Sample records for challenges facing modern

  1. District of Columbia: D.C. Public Schools' Modernization Program Faces Major Challenges. Testimony before the Subcommittee on the District of Columbia, Committee on Appropriations, House of Representatives.

    ERIC Educational Resources Information Center

    Cooper, David E.

    This Congressional testimony focuses on the challenges faced by the District of Columbia in modernizing its public schools. Specifically, it addresses: (1) increases in the cost of modernizing the schools; (2) delays in completing the schools; (3) quality inspection problems; and (4) concerns about managing asbestos hazards. The testimony…

  2. A New Rootedness? Education in the Technological Age

    ERIC Educational Resources Information Center

    Glendinning, Simon

    2018-01-01

    This paper explores the challenges facing educators in a time when modern technology, and especially modern social technology, has an increasingly powerful hold on our lives. The educational challenge does not primarily concern questions concerning the use of technology in the classroom, or as part of the learning environment, but a changeover in…

  3. Modernization of Management: Social and Socio-Cultural Aspects

    ERIC Educational Resources Information Center

    Vinogradova, Marina V.; Babakaev, Sergy V.; Larionova, Anna A.; Kobyak, Marina V.; Layko, Mikhail Y.

    2016-01-01

    The relevance of the topic is determined by the new challenges faced by the Russian state in modern conditions that have a significant impact on public administration, which entails the need for its comprehensive modernization. In this regard, this article is aimed at the disclosure of social and socio-cultural aspects of the modernization of…

  4. Education as an intergenerational process of human learning, teaching, and development.

    PubMed

    Cole, Michael

    2010-11-01

    In this article I argue that the future of psychological research on educational processes would benefit from an interdisciplinary approach that enables psychologists to locate their objects of study within the cultural, social, and historical contexts of their research. To make this argument, I begin by examining anthropological accounts of the characteristics of education in small, face-to-face, preindustrial societies. I then turn to a sample of contemporary psychoeducational research that seeks to implement major, qualitative changes in modern educational practices by transforming them to have the properties of education in those self-same face-to-face societies. Next I examine the challenges faced by these modern approaches and briefly describe a multi-institutional, multidisciplinary system of education that responds to these challenges while offering a model for educating psychology students in a multigenerational system of activities with potential widespread benefits. PsycINFO Database Record (c) 2010 APA, all rights reserved.

  5. The Challenge of Modern Church-Public Relations.

    ERIC Educational Resources Information Center

    Reagen, Michael V., Ed.; Chertow, Doris S., Ed.

    Papers presented at the Institute on Modern Religious Communication Dilemmas, held at Syracuse University's Continuing Education Center for the Public Service in November 1971, are provided. The focus of the institute was the dilemmas facing modern church-public relations practitioners. The papers reproduced in this book provide a descriptive…

  6. Childhood and Citizenship: A Conversation across Modernity

    ERIC Educational Resources Information Center

    Dunne, Joseph

    2006-01-01

    This paper analyses the problematic nature of citizenship as a modern achievement faced with the challenge of vindicating ancient ideals in what is increasingly considered to be a "postmodern" world. It offers a parallel analysis of childhood as a characteristically modern construct whose reality in children's life-worlds is threatened…

  7. Madrasa Education in South Asia and Southeast Asia: Current Issues and Debates

    ERIC Educational Resources Information Center

    Park, Jaddon; Niyozov, Sarfaroz

    2008-01-01

    Madaris (plural of madrasa) face a multitude of challenges in preparing students for life in rapidly modernising societies and emerging globalised knowledge economies. The complexity of the role and tasks of madaris, which are caught in the interface of modernity and tradition, the challenges they face, and the strategies they develop to address…

  8. Introducing Decision Making under Uncertainty and Strategic Considerations in Engineering Design

    ERIC Educational Resources Information Center

    Kosmopoulou, Georgia; Jog, Chintamani; Freeman, Margaret; Papavassiliou, Dimitrios V.

    2010-01-01

    Chemical Engineering graduates will face challenges at the workplace that even their peers who graduated a few years ago were not expected to face. One such major challenge is the management and operation of companies and plants under conditions of uncertainty and the need to make decisions in competitive situations. Modern developments in…

  9. Credible Leadership: Exploring Differences in Perception of the Credibility of the Senior Student Affairs Officer among CIC College Presidents and Their Senior Leadership Teams

    ERIC Educational Resources Information Center

    Powers, Wendy A.

    2014-01-01

    Modern higher education institutions face tremendous challenges, including dwindling financial resources, waning public support, demands for greater accountability, and daunting student needs and expectations. Campus presidents simply cannot face these challenges as isolated or solitary leaders. High functioning, inclusive, collaborative, and…

  10. Exploring Leadership within the Modern Organization: Understanding the Dynamics of Effective Leadership of a Virtual, Multigenerational Workforce

    ERIC Educational Resources Information Center

    Schultz, Roger W.

    2010-01-01

    This study examined a relatively new but growing set of leadership challenges that the leader of the modern organization faces more frequently due to the dynamics of the workplace. The new challenges involve leading a workforce virtually, in that more frequently workers are physically dispersed away from the leader and fellow workers. The second…

  11. Innovative work behavior of managers: Implications regarding stressful challenges of modernized public- and private-sector organizations

    PubMed Central

    Mukherjee, Sudeshna Basu; Ray, Anjali

    2009-01-01

    Background: The present study was firstly aimed to find out the nature of stressful life events arising out of the innovative challenges in modernized organizations; and secondly, it tried to identify the relationship between innovative work behavior of managers and the levels of stress arising out of stressful events in modernized organizations (public and private) in West Bengal. Materials and Methods: Data was collected from a sample of 200 managers, by using 3 tools (General Information Schedule, Life Event Inventory and Innovative Work Behavior Scale) through a face-to-face interview. Responses were subjected to both quantitative and qualitative analyses. The data was statistically treated for ‘t’ and ANOVA. Results: Data highlighted the fact that the qualitative profile of stressful events in the lives of managers expressed specificity in terms of their organizational type (public- and private-sector modernized organizations), and levels of stress from stressful life events were significantly higher among the modernized private-sector managers than those among public-sector managers. The prevalence of innovative work behavior was moderately higher among managers of private-sector modernized organizations than their counterparts in public-sector organizations. The trends of innovative work behavior of the managers indicated much variability due to interaction of their level of perceived stressful challenges for innovation and the global forces of change that have unleashed dynamic, systematic and higher expectation level from them. PMID:21180486

  12. Innovative work behavior of managers: Implications regarding stressful challenges of modernized public- and private-sector organizations.

    PubMed

    Mukherjee, Sudeshna Basu; Ray, Anjali

    2009-07-01

    The present study was firstly aimed to find out the nature of stressful life events arising out of the innovative challenges in modernized organizations; and secondly, it tried to identify the relationship between innovative work behavior of managers and the levels of stress arising out of stressful events in modernized organizations (public and private) in West Bengal. Data was collected from a sample of 200 managers, by using 3 tools (General Information Schedule, Life Event Inventory and Innovative Work Behavior Scale) through a face-to-face interview. Responses were subjected to both quantitative and qualitative analyses. The data was statistically treated for 't' and ANOVA. Data highlighted the fact that the qualitative profile of stressful events in the lives of managers expressed specificity in terms of their organizational type (public- and private-sector modernized organizations), and levels of stress from stressful life events were significantly higher among the modernized private-sector managers than those among public-sector managers. The prevalence of innovative work behavior was moderately higher among managers of private-sector modernized organizations than their counterparts in public-sector organizations. The trends of innovative work behavior of the managers indicated much variability due to interaction of their level of perceived stressful challenges for innovation and the global forces of change that have unleashed dynamic, systematic and higher expectation level from them.

  13. Modernization of the Cassini Ground System

    NASA Technical Reports Server (NTRS)

    Razo, Gus; Fujii, Tammy J.

    2014-01-01

    The Cassini Spacecraft and its ground system have been operational for over 16 years. Modernization presents several challenges due to the personnel, processes, and tools already invested and embedded into the current ground system structure. Every mission's ground system has its own unique complexities and challenges, involving various organizational units. As any mission from its inception to its execution, schedules are always tight. This forces GDS engineers to implement a working ground system that is not necessarily fully optimized. Ground system challenges increase as technology evolves and cyber threats become more sophisticated. Cassini's main challenges were due to its ground system existing before many security requirements were levied on the multi-mission tools and networks. This caused a domino effect on Cassini GDS tools that relied on outdated technological features. In the aerospace industry reliable and established technology is preferred over innovative yet less proven technology. Loss of data for a spacecraft mission can be catastrophic; therefore, there is a reluctance to make changes and updates to the ground system. Nevertheless, all missions and associated teams face the need to modernize their processes and tools. Systems development methods from well-known system analysis and design principles can be applied to many missions' ground systems. Modernization should always be considered, but should be done in such a way that it does not affect flexibility nor interfere with established practices. Cassini has accomplished a secure and efficient ground data system through periodic updates. The obstacles faced while performing the modernization of the Cassini ground system will be outlined, as well as the advantages and challenges that were encountered.

  14. Should pediatric neurosurgeons still manage neurotrauma today?

    PubMed

    Peter, Jonathan C

    2010-02-01

    Neurotrauma remains a major global burden of injury, especially for young patients, and will consequently always be a condition that pediatric neurosurgeons are called upon to treat. However, the face of modern neurotrauma management is changing, presenting important challenges to today's pediatric neurosurgeons. This article summarizes some of the issues in neurotrauma facing clinicians whose responsibility it is to treat these children. It is up to the individual neurosurgeon to familiarize him- or herself with the emerging literature on the modern management of pediatric neurotrauma.

  15. Facing the Knowledge Society: Mexico's Public Universities

    ERIC Educational Resources Information Center

    Varela-Petito, Gonzalo

    2010-01-01

    Public higher education in Mexico faces major challenges vis-a-vis its position within the modern knowledge society, sparking concern among educational authorities. In the second half of the 20th century Mexican universities ceased to be selective, elitist schools, becoming, instead, massive institutions that reflect social and intellectual…

  16. A Study of the Use of Pairwise Comparison in the Context of Social Online Moderation

    ERIC Educational Resources Information Center

    Tarricone, Pina; Newhouse, C. Paul

    2016-01-01

    Traditional moderation of student assessments is often carried out with groups of teachers working face-to-face in a specified location making judgements concerning the quality of representations of achievement. This traditional model has relied little on modern information communications technologies and has been logistically challenging. We…

  17. The Chinese Family in Transition: Implications for Education and Society in Modern Taiwan.

    ERIC Educational Resources Information Center

    Smith, Douglas C.

    This paper investigates the challenges facing the modern Chinese family in Taiwan. An understanding of how culture and family life interact in other cultures may be useful in helping to understand such interactions in one's own society. Confucianism and family stability have been two enduring features of the protracted civilizations of China. In…

  18. The Bachelor of Arts: Slipping into the Twilight or Facing a New Dawn?

    ERIC Educational Resources Information Center

    Gannaway, Deanne

    2015-01-01

    Undergraduate students have historically engaged with the humanities and social sciences through the Bachelor of Arts (BA) degree programme. Recent experiences suggest that the relevance and the value of the degree to the modern world is now being challenged: populist press questions the value of the humanities to the modern knowledge economy;…

  19. Facing the Globalisation Challenge in the Realm of English Language Teaching.

    ERIC Educational Resources Information Center

    Sifakis, Nicos C.; Sougari, Areti-Maria

    2003-01-01

    Addresses the challenge of globalization with respect to English language teaching and particularly teaching English to speakers of foreign languages. Argues that some of the primary issues involved concern the increasing role of technology and communication in modern societies and the looming conflict between local communities and the…

  20. The Young Military Child: Our Modern Telemachus

    ERIC Educational Resources Information Center

    Cozza, Stephen J.; Lieberman, Alicia F.

    2007-01-01

    For thousands of years military children have been faced with many challenges that result from the combat deployment of their parents. These challenges are likely to be particularly burdensome to infants, toddlers, and preschoolers because of their emotional and cognitive immaturity, their reliance on magical thinking, and their dependence upon…

  1. Listen to the Urgent Sound of Drums: Major Challenges in African Higher Education

    ERIC Educational Resources Information Center

    Visser, Herman

    2008-01-01

    African higher education is currently facing tremendous challenges. The pressure and demand for access is huge. This is understandable against the background of traditionally low participation, low success and throughput rates, declining financial contributions from governments and donors, and critical pressures for efficiency, modernization,…

  2. A Working Model of a New American University

    ERIC Educational Resources Information Center

    Crow, Michael M.; Loui, Kimberly

    2006-01-01

    American universities confront unique challenges as they move into the twenty-first century. These include rapid population growth, demographic and economic changes on both global and regional levels, and the numerous local challenges that face today's communities. Modern universities must engage, and in turn be engaged by, their communities in…

  3. Collision induced unfolding of isolated proteins in the gas phase: past, present, and future.

    PubMed

    Dixit, Sugyan M; Polasky, Daniel A; Ruotolo, Brandon T

    2018-02-01

    Rapidly characterizing the three-dimensional structures of proteins and the multimeric machines they form remains one of the great challenges facing modern biological and medical sciences. Ion mobility-mass spectrometry based techniques are playing an expanding role in characterizing these functional complexes, especially in drug discovery and development workflows. Despite this expansion, ion mobility-mass spectrometry faces many challenges, especially in the context of detecting small differences in protein tertiary structure that bear functional consequences. Collision induced unfolding is an ion mobility-mass spectrometry method that enables the rapid differentiation of subtly-different protein isoforms based on their unfolding patterns and stabilities. In this review, we summarize the modern implementation of such gas-phase unfolding experiments and provide an overview of recent developments in both methods and applications. Copyright © 2017 Elsevier Ltd. All rights reserved.

  4. Introducing Risk Analysis and Calculation of Profitability under Uncertainty in Engineering Design

    ERIC Educational Resources Information Center

    Kosmopoulou, Georgia; Freeman, Margaret; Papavassiliou, Dimitrios V.

    2011-01-01

    A major challenge that chemical engineering graduates face at the modern workplace is the management and operation of plants under conditions of uncertainty. Developments in the fields of industrial organization and microeconomics offer tools to address this challenge with rather well developed concepts, such as decision theory and financial risk…

  5. Challenges Faced by Key Stakeholders Using Educational Online Technologies in Blended Tertiary Environments

    ERIC Educational Resources Information Center

    Tuapawa, Kimberley

    2016-01-01

    Traditional learning spaces have evolved into dynamic blended tertiary environments (BTEs), providing a modern means through which tertiary education institutes (TEIs) can augment delivery to meet stakeholder needs. Despite the significant demand for web-enabled learning, there are obstacles concerning the use of EOTs, which challenge the…

  6. Meeting the challenges of case management with remote patient monitoring technology.

    PubMed

    Cherry, J C; Colliflower, S J; Tsiperfal, A

    2000-01-01

    The article presents an overview of some of the current trends in health care and the challenges faced by nurse case managers who are providing disease management services. It discusses some of the emerging technologies available today for innovative case management. In particular, this article describes a program run by a healthcare system in Sacramento, California that uses an Internet-based technology to enhance their nurse case management model. The article demonstrates how the Health Hero platform enables interactive communication between nurse case managers and their patients, thereby meeting some of the challenges the nurse case managers are faced with in the modern disease-management world.

  7. Meeting the Challenge of IS Curriculum Modernization: A Guide to Overhaul, Integration, and Continuous Improvement

    ERIC Educational Resources Information Center

    McGann, Sean T.; Frost, Raymond D.; Matta, Vic; Huang, Wayne

    2007-01-01

    Information Systems (IS) departments are facing challenging times as enrollments decline and the field evolves, thus necessitating large-scale curriculum changes. Our experience shows that many IS departments are in such a predicament as they have not evolved content quickly enough to keep it relevant, they do a poor job coordinating curriculum…

  8. Universities on the Market: Academic Capitalism as a Challenge and a Window of Opportunity

    ERIC Educational Resources Information Center

    Demin, M. R.

    2017-01-01

    The modern university and the academic profession itself are facing new challenges: First, the increasing complexity of labor markets and globalization are undermining the structure of the academic profession, and secondly, the rise in cost of university research calls into question the autonomy of the university. The internationalization of the…

  9. Technological Innovation of Higher Education in New Zealand: A Wicked Problem?

    ERIC Educational Resources Information Center

    Marshall, Stephen

    2016-01-01

    New Zealand, like many countries, faces the challenge of building and sustaining an educated population. Particular challenges are posed by the need to educate an increasing proportion of the population to higher levels in order to support the growth of a modern skills and knowledge economy, as opposed to an economy built on low-cost labour and…

  10. Ask the experts: automation: part I.

    PubMed

    Allinson, John L; Blick, Kenneth E; Cohen, Lucinda; Higton, David; Li, Ming

    2013-08-01

    Bioanalysis invited a selection of leading researchers to express their views on automation in the bioanalytical laboratory. The topics discussed include the challenges that the modern bioanalyst faces when integrating automation into existing drug-development processes, the impact of automation and how they envision the modern bioanalytical laboratory changing in the near future. Their enlightening responses provide a valuable insight into the impact of automation and the future of the constantly evolving bioanalytical laboratory.

  11. Temporal and Dose-response Pathway Analysis for Predicting Chronic Chemical Toxicity

    EPA Science Inventory

    Current challenges facing chemical risk assessment are the time and resources required to meet the data standards necessary for a published assessment and the incorporation of modern biological information. The integration of toxicogenomics into the risk assessment paradigm may ...

  12. US EPA CSO CAPSTONE REPORT: THE CSO PROBLEM

    EPA Science Inventory

    The history of combined sewer systems (CSS) and combined sewer overflows (CSOs) in the US provides unique insights into the complex challenge faced in reducing and eliminating their adverse environmental effects. The evolution of the "modern" CSS shows how early urban drainag sys...

  13. The changing face of hemostasis testing in modern laboratories: consolidation, automation, and beyond.

    PubMed

    Lippi, Giuseppe; Plebani, Mario; Favaloro, Emmanuel J

    2015-04-01

    The reality of laboratory diagnostics as a whole, and hemostasis testing in particular, is evolving under new paradigms of efficiency. The driving forces of health care and laboratory diagnostics in the third millennium are mainly represented by macro- and microeconomics. In a world with limited resources, shattered by an unprecedented economic crisis, laboratory diagnostics is undergoing a substantial reorganization, with emergence of new models under the imperative of terms, such as bedside testing, consolidation, and networking. The paradigms under which these changes are being developed include a variety of environment, preanalytical, technological, professional, and health-care aspects. The maintenance of continued quality is indeed the major challenge to be faced in the foreseeable future. In fact, some challenges prepotently emerge during a consolidation process, which basically involve delayed testing, centrifugation, transportation, and stability of the specimens, as well as the potential mismatch of sample matrix. This article is aimed to provide an overview of the current economic scenario of laboratory diagnostics and discuss the changing face of hemostasis testing in modern laboratories, providing a synthetic overview about potential drawbacks of actualized solutions. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

  14. Intercity passenger rail : Amtrak faces challenges in improving its financial condition : statement of Phyllis F. Scheinberg

    DOT National Transportation Integrated Search

    1999-10-28

    The Rail Passenger Service Act of 1970 created Amtrak as the nation's intercity passenger railroad. The act, as amended, gave Amtrak a number of goals, including providing modern, efficient intercity passenger rail service; giving Americans an altern...

  15. Enthusiasm and the Effective Modern Academic

    ERIC Educational Resources Information Center

    Freudenberg, Brett; Samarkovski, Lisa

    2014-01-01

    Academics today face an array of challenges to their enthusiasm, including teaching students from diverse backgrounds with wavering levels of engagement with their studies. Furthermore, reform to the tertiary education sector has seen the corporatisation of universities with management increasingly measuring academic outcomes in respect of both…

  16. Human Factors Guidance for Control Room and Digital Human-System Interface Design and Modification, Guidelines for Planning, Specification, Design, Licensing, Implementation, Training, Operation and Maintenance

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    R. Fink, D. Hill, J. O'Hara

    2004-11-30

    Nuclear plant operators face a significant challenge designing and modifying control rooms. This report provides guidance on planning, designing, implementing and operating modernized control rooms and digital human-system interfaces.

  17. Measuring Distance Learning Performance with Data Envelopment Analysis

    ERIC Educational Resources Information Center

    Xiaoming, Yang; Shieh, Chich-Jen; Wu, Wu-Chung

    2014-01-01

    In the modern society with changeable information technology learning and applications, students could acquire information application knowledge, which is not worse than those taught by teachers in classrooms, through the Internet, distance conference, and e-learning. Traditional instruction therefore is facing great challenges. When measuring the…

  18. Apprenticeships in England: What Next?

    ERIC Educational Resources Information Center

    Hogarth, Terence; Gambin, Lynn; Hasluck, Chris

    2012-01-01

    This paper examines recent development in Apprenticeship training in England. Since the introduction of Modern Apprenticeships in the mid-1990s this form of training has been subject to much analysis and reform. This paper summarises the current situation and highlights some of the challenges and opportunities which face Apprenticeship over the…

  19. Intercultural Communication and the New American Campus

    ERIC Educational Resources Information Center

    Bennett, Janet M.; Salonen, Riikka

    2007-01-01

    Modern educators face new challenges both in teaching about culture, and in teaching across cultures. While culture is often addressed in the "content" of the curriculum, it is less frequently incorporated into the "process" of teaching and learning. In short, cultural knowledge does not equal intercultural competence. Being global citizens…

  20. Financial management in leading health care systems.

    PubMed

    Smith, D G; Wheeler, J R; Rivenson, H L; Reiter, K L

    2000-01-01

    To understand better the financial management practices and strategies of modern health care organizations, we conducted interviews with chief financial officers (CFOs) of several leading health care systems. In this introduction, we present an overview of the project and summary responses on corporate financial structures and strategic challenges facing CFOs.

  1. Overcoming Adversity: Resilience Development Strategies for Educational Leaders

    ERIC Educational Resources Information Center

    Farmer, Tod Allen

    2010-01-01

    School leadership has never been easy. However, some experts like Garcia (2005) wrote that current school leaders are facing a variety of difficulties that make sustaining school reform efforts exceedingly difficult. Collectively, these modern day challenges have the capacity to form the perfect storm. School leaders need effective strategies to…

  2. 'To die with dignity': an update on Palliative Care.

    PubMed

    Brennan, Frank

    2017-08-01

    Significant developments have occurred in the discipline of palliative care in the modern era. This paper shall explore those developments, challenge some widely held misconceptions about the role and daily practice of the discipline, highlight the growing recognition of the role of palliative care in non-malignant diseases, briefly discuss innovations in symptom management and reflect on the underlying principles, maturation and challenges faced by the discipline. © 2017 Royal Australasian College of Physicians.

  3. Major Challenges for the Modern Chemistry in Particular and Science in General.

    PubMed

    Uskokovíc, Vuk

    2010-11-01

    In the past few hundred years, science has exerted an enormous influence on the way the world appears to human observers. Despite phenomenal accomplishments of science, science nowadays faces numerous challenges that threaten its continued success. As scientific inventions become embedded within human societies, the challenges are further multiplied. In this critical review, some of the critical challenges for the field of modern chemistry are discussed, including: (a) interlinking theoretical knowledge and experimental approaches; (b) implementing the principles of sustainability at the roots of the chemical design; (c) defining science from a philosophical perspective that acknowledges both pragmatic and realistic aspects thereof; (d) instigating interdisciplinary research; (e) learning to recognize and appreciate the aesthetic aspects of scientific knowledge and methodology, and promote truly inspiring education in chemistry. In the conclusion, I recapitulate that the evolution of human knowledge inherently depends upon our ability to adopt creative problem-solving attitudes, and that challenges will always be present within the scope of scientific interests.

  4. Major Challenges for the Modern Chemistry in Particular and Science in General

    PubMed Central

    Uskokovíc, Vuk

    2013-01-01

    In the past few hundred years, science has exerted an enormous influence on the way the world appears to human observers. Despite phenomenal accomplishments of science, science nowadays faces numerous challenges that threaten its continued success. As scientific inventions become embedded within human societies, the challenges are further multiplied. In this critical review, some of the critical challenges for the field of modern chemistry are discussed, including: (a) interlinking theoretical knowledge and experimental approaches; (b) implementing the principles of sustainability at the roots of the chemical design; (c) defining science from a philosophical perspective that acknowledges both pragmatic and realistic aspects thereof; (d) instigating interdisciplinary research; (e) learning to recognize and appreciate the aesthetic aspects of scientific knowledge and methodology, and promote truly inspiring education in chemistry. In the conclusion, I recapitulate that the evolution of human knowledge inherently depends upon our ability to adopt creative problem-solving attitudes, and that challenges will always be present within the scope of scientific interests. PMID:24465151

  5. Effects of Positive Behavior Interventions and Supports on Middle School Student Achievement

    ERIC Educational Resources Information Center

    Knowles, Chad Allen

    2014-01-01

    Today's teachers face more frequent and more severe challenges than perhaps any generation of teachers that have come before them. Administrators attempt to support teaching in an environment of ever-increasing accountability and dwindling financial resources with new and innovative strategies. One such strategy employed by modern educators has…

  6. Learning to See with Different Eyes: A Nietzschean Challenge to Multicultural Dialogue

    ERIC Educational Resources Information Center

    Yacek, Douglas W.

    2014-01-01

    Empathy is a necessity in our multicultural world. Modern democratic societies are home to communities with the most diverse religious, political, and moral convictions, and these convictions often directly, even perilously, contradict one another. Educational theorists differ on how empathy can be taught in the face of these contradictions. Does…

  7. Elite Education and the State in France: Durable Ties and New Challenges

    ERIC Educational Resources Information Center

    van Zanten, Agnès; Maxwell, Claire

    2015-01-01

    Employing a Weberian understanding of the centrality of a strong bureaucracy in the modern nation-state, this article examines the relationship between the state and elite education in France. Through a historical analysis and an examination of two current issues facing education--widening participation and pressures to internationalise--we…

  8. A Guided Inquiry on Hubble Plots and the Big Bang

    ERIC Educational Resources Information Center

    Forringer, Ted

    2014-01-01

    In our science for non-science majors course "21st Century Physics," we investigate modern "Hubble plots" (plots of velocity versus distance for deep space objects) in order to discuss the Big Bang, dark matter, and dark energy. There are two potential challenges that our students face when encountering these topics for the…

  9. The Human Face as a Dynamic Tool for Social Communication.

    PubMed

    Jack, Rachael E; Schyns, Philippe G

    2015-07-20

    As a highly social species, humans frequently exchange social information to support almost all facets of life. One of the richest and most powerful tools in social communication is the face, from which observers can quickly and easily make a number of inferences - about identity, gender, sex, age, race, ethnicity, sexual orientation, physical health, attractiveness, emotional state, personality traits, pain or physical pleasure, deception, and even social status. With the advent of the digital economy, increasing globalization and cultural integration, understanding precisely which face information supports social communication and which produces misunderstanding is central to the evolving needs of modern society (for example, in the design of socially interactive digital avatars and companion robots). Doing so is challenging, however, because the face can be thought of as comprising a high-dimensional, dynamic information space, and this impacts cognitive science and neuroimaging, and their broader applications in the digital economy. New opportunities to address this challenge are arising from the development of new methods and technologies, coupled with the emergence of a modern scientific culture that embraces cross-disciplinary approaches. Here, we briefly review one such approach that combines state-of-the-art computer graphics, psychophysics and vision science, cultural psychology and social cognition, and highlight the main knowledge advances it has generated. In the light of current developments, we provide a vision of the future directions in the field of human facial communication within and across cultures. Copyright © 2015 Elsevier Ltd. All rights reserved.

  10. Challenges in Modern Anti-Doping Analytical Science.

    PubMed

    Ayotte, Christiane; Miller, John; Thevis, Mario

    2017-01-01

    The challenges facing modern anti-doping analytical science are increasingly complex given the expansion of target drug substances, as the pharmaceutical industry introduces more novel therapeutic compounds and the internet offers designer drugs to improve performance. The technical challenges are manifold, including, for example, the need for advanced instrumentation for greater speed of analyses and increased sensitivity, specific techniques capable of distinguishing between endogenous and exogenous metabolites, or biological assays for the detection of peptide hormones or their markers, all of which require an important investment from the laboratories and recruitment of highly specialized scientific personnel. The consequences of introducing sophisticated and complex analytical procedures may result in the future in a change in the strategy applied by the Word Anti-Doping Agency in relation to the introduction and performance of new techniques by the network of accredited anti-doping laboratories. © 2017 S. Karger AG, Basel.

  11. Modern Natural Products Drug Discovery and its Relevance to Biodiversity Conservation†

    PubMed Central

    Kingston, David G. I.

    2010-01-01

    Natural products continue to provide a diverse and unique source of bioactive lead compounds for drug discovery, but maintaining their continued eminence as source compounds is challenging in the face of the changing face of the pharmaceutical industry and the changing nature of biodiversity prospecting brought about by the Convention of Biodiversity. This review provides an overview of some of these challenges, and suggests ways in which they can be addressed so that natural products research can remain a viable and productive route to drug discovery. Results from International Cooperative Biodiversity Groups (ICBGs) working in Madagascar, Panama, and Suriname are used as examples of what can be achieved when biodiversity conservation is linked to drug discovery. PMID:21138324

  12. Academic Expectations and Well-Being from School to Work during the Economic Downturn

    ERIC Educational Resources Information Center

    Salmela-Aro, Katariina

    2012-01-01

    Educational transitions and the transition from school to working life present substantial challenges for youth in modern societies. In addition to the drastic changes taking place in their personal lives as they navigate the educational ladder and the transition to work life, young adults today face profound changes in society as well. In…

  13. Humanities: The Unexpected Success Story of the Twenty-First Century

    ERIC Educational Resources Information Center

    Davis, Virginia

    2012-01-01

    Humanities within universities faced challenges in the latter half of the twentieth century as their value in the modern world was questioned. This paper argues that there is strong potential for the humanities to thrive in the twenty-first century university sector. It outlines some of the managerial implications necessary to ensure that this…

  14. Aeronautical Engineering and Aerospace Engineering: A Learner-Centered Teaching Perspective in Higher Education

    ERIC Educational Resources Information Center

    Gohardani, Omid; Gohardani, Amir S.; Dokter, Erin; Macario, Kyla

    2014-01-01

    Teaching in the 21st century requires a modern teaching practice coherent with the evolutions of the Information Age. Interestingly, teaching practices have stretched beyond an art form and into the realm of science. Following these scientific trails, one can argue that one of the greatest challenges educators currently face is to maintain student…

  15. Feedback on Second Language Pronunciation: A Case Study of EAP Teachers' Beliefs and Practices

    ERIC Educational Resources Information Center

    Baker, Amanda; Burri, Michael

    2016-01-01

    In the modern English language classroom, teachers are often faced with the challenging task of supporting students to achieve comprehensible pronunciation, but many teachers limit or neglect giving students feedback on their pronunciation for a variety of reasons. This paper examines the case of five experienced English for Academic Purposes…

  16. An Innovative Plant Genomics and Gene Annotation Program for High School, Community College, and University Faculty

    ERIC Educational Resources Information Center

    Hacisalihoglu, Gokhan; Hilgert, Uwe; Nash, E. Bruce; Micklos, David A.

    2008-01-01

    Today's biology educators face the challenge of training their students in modern molecular biology techniques including genomics and bioinformatics. The Dolan DNA Learning Center (DNALC) of Cold Spring Harbor Laboratory has developed and disseminated a bench- and computer-based plant genomics curriculum for biology faculty. In 2007, a five-day…

  17. Travelling Teens: A Parents' Guide to Family Relocation

    ERIC Educational Resources Information Center

    Linke, Pam

    2005-01-01

    Moving house is becoming a more common aspect of modern life; but this does not make it any easier to cope with the many issues that arise--from the everyday practicalities, to the social and emotional challenges involved. Families who are required to relocate face the potentially difficult task of settling each family member into the new…

  18. Together, Not Alone: Positive Peer Culture in a German School

    ERIC Educational Resources Information Center

    Opp, Gunther; Unger, Nicola; Teichmann, Jana

    2007-01-01

    The many sea-changes in German culture have given rise to a growing population of children and youth at risk. This article describes the creation of a Positive Peer Culture in a special school for students with emotional and behavioural problems. The authors review challenges facing youth in modern Germany, the implementation of the PPC program,…

  19. Surviving the deepening downturn

    Treesearch

    Urs Buehlmann; Matt Bumgardner; Al Schuler; Jeff Crissey

    2009-01-01

    With the housing crisis having spread to the entire economy, woodworking companies face challenges to position themselves for future opportunities for profits and growth. What is the industry doing to sustain itself? As a follow-up to last year's survey, an exclusive study by Virginia Tech, the U.S. Forest Service and Modern Woodworking took an updated look at the...

  20. The importance of context in the evolution of health promotion.

    PubMed

    Sparks, Michael

    2013-06-01

    The world has changed dramatically since the Ottawa Charter was developed in 1986. Contemporary health promotion responses continue to evolve and become more sophisticated in response to the multiple challenges created by an ever-changing world. This commentary discusses some of the challenges facing health promotion professionals today and some of the responses that are being developed to address them. The importance of contextual considerations for both the worker and the work of health promotion are emphasised. The author then suggests ways that organisations and individuals can meet modern-day health promotion challenges through specific courses of action.

  1. A Values Base for the Norwegian Kindergarten: Common Ground across Cultural Affiliations?

    ERIC Educational Resources Information Center

    Hovdelien, Olav

    2013-01-01

    One of the major challenges facing modern-day secular states is the issue of social integration. The issue discussed in this article is how it is possible to arrive at unifying values in a multicultural society that is characterised by secularisation and disintegration of the Christian hegemony of former times on the one hand and by the emergence…

  2. Keynote: Going to University--Blended Strategies for Learning and Teaching in a Modern Tertiary Context

    ERIC Educational Resources Information Center

    Forbes, Dianne

    2016-01-01

    This think piece is a follow-up to a keynote delivered at the biennial DEANZ Conference, at the University of Waikato in Hamilton, New Zealand, in April 2016. It explores the University of Waikato's Mixed Media Pathway. Dianne Forbes ponders her own experiences as a tertiary student, considers some of the changes and challenges facing universities…

  3. "Was Isaac Sacrificed in the End?" Reading Midrash in Elementary School

    ERIC Educational Resources Information Center

    Sigel, Deena

    2009-01-01

    The Torah teacher faces a dilemma of how to teach complex, ancient, sacred texts to modern children. How can she convey the relationship between rabbinic commentary and Scripture? This article recounts the story--and the challenges--of one midrash mini-course that I taught an American class as part of a wider research project. The aim of the…

  4. Cars and Kinetic Energy--Some Simple Physics with Real-World Relevance

    ERIC Educational Resources Information Center

    Parthasarathy, Raghuveer

    2012-01-01

    Understanding energy usage is crucial to understanding modern civilization, as well as many of the challenges it faces. Energy-related issues also offer real-world examples of important physical concepts, and as such have been the focus of several articles in "The Physics Teacher" in the past few decades (e.g., Refs. 1-5, noted further below).…

  5. Research on the Direction of China's Energy Development and Coping Strategies Based on the Trend of World Energy Development

    NASA Astrophysics Data System (ADS)

    Zhang, Lixin; Tao, Ye; Jiang, Yan; Ma, Ju

    2018-06-01

    To realize the modernization of the national economy, it is necessary to develop energy science and technology for China,which is third largest countries in the world.The rapid development of science and technology has promoted the continuous transformation of the global energy industry. By analyzing the trend of energy development in the world today, this paper discusses the challenges that the global energy development facing and the situation and tasks faced by China's energy sustainable development, and looks forward to China's strategies to cope with the development of the world's energy.

  6. Driving and flying with epilepsy.

    PubMed

    Drazkowski, Joseph F

    2007-07-01

    Transportation issues in industrialized nations play an important role in the lives of most citizens. The acts of flying and driving, especially in the United States, intersect with many peoples' lives on almost a daily basis. Although some larger cities have modern and efficient public transportation systems, many do not, thus placing considerable responsibility on the individual to manage their own transportation needs. A person with epilepsy faces considerable challenges when it comes to transportation. Defining these challenges and understanding how to deal with the person with epilepsy and transportation issues is the focus of this article.

  7. New Challenges, New Mindsets, New Disciplines: Transforming the SEA into a Modern Performance Organization. Solutions. Issue No. 1

    ERIC Educational Resources Information Center

    Gross, Betheny; Jochim, Ashley; Nafziger, Dean

    2013-01-01

    State education agencies (SEAs) are under fire and face new expectations from all sides. The federal government, state legislatures and governors, and citizens themselves are calling upon the SEA to do "more"--more to improve outcomes for students, more to close the achievement gap, and more to meet the diverse instructional needs of students.…

  8. Seven Rules on Having a Happy Marriage along with Work

    ERIC Educational Resources Information Center

    Maatta, Kaarina; Uusiautti, Satu

    2012-01-01

    In modern society, men and women want to have a successful marriage and a career. However, people are faced with new demands at work and home, and therefore, finding a balance between work and family life is a real challenge. In this article, the data consist of stories written by Finns who have been married for more than 10 years (N = 342 married…

  9. Improving Peer Learning for Students' Academic Performance: The Case of Second Year Rural Development and Agricultural Extension Students, College of Agriculture, Wolaita Sodo University

    ERIC Educational Resources Information Center

    Gebeyehu, Bogale; Regasa, Guta

    2016-01-01

    Modern universities are facing challenges due to the increasing number of young people attending higher education. The sheer number of students raises the question of how to organize teaching-learning activities that allow the students to become active learners and engaged participants in academic discussions within their disciplines rather than…

  10. Experiences from the implementation of a biosafety system in Slovenia.

    PubMed

    Milavec, Mojca; Racman, Darja Stanic

    2007-09-01

    The development and implementation of an effective national biosafety system is important for several key reasons: to ensure safe access to products of modern biotechnology, to build public confidence, to encourage the growth of domestic modern biotechnology, and to comply with international standards and agreements. There is no single best approach in the development and implementation of a national biosafety system and each country is faced with unique challenges. Slovenia is a small country and a new EU Member State. However, it has developed and implemented an efficient national biosafety system. The key elements of this system are administrative procedure, risk assessment, enforcement, and public participation and information.

  11. Marine data management: from early explorers to e-infrastructures (Ian McHarg Medal Lecture)

    NASA Astrophysics Data System (ADS)

    Glaves, Helen

    2016-04-01

    Ocean observations have been made for as long as Man has been exploring the seas. Early Phoenician and Viking explorers developed extensive knowledge of currents, tides and weather patterns that they shared directly with their peers. Eighteenth century log books from whaling ships and the voyages of explorers, such as Captain Cook, documented sea conditions and weather patterns, and it is these records that are used today to extend oceanographic records back to a time before systematic observing of the ocean began. This historical information is now being used to address the grand challenges being faced by Society in the 21st century in ways that the 18th century seafarers could never have imagined. Systematic ocean observation and the science of modern oceanography began in the late 19th century with the voyages of HMS Challenger. Since these early scientific cruises ocean observation has become more and more sophisticated. Increasingly diverse types of equipment mounted on different types of platforms are generating huge amounts of data delivered in a variety of formats and conforming to a range of standards and best practice. It is this heterogeneity of marine data that has presented one of the greatest challenges for the modern researcher. As marine research becomes increasingly international, cross-disciplinary and multiscale, it presents new and more complex challenges for data stewardship. Increasingly large volumes of interoperable data are needed to address fundamental questions such as the assessment of Man's impact on the marine environment or the sustainable exploitation of available marine resources whilst maintaining the good environmental status of the ocean. This presentation will provide a brief overview of the acquisition and sharing of information about the marine environment from the earliest explorers to the modern day. It will look at some of the challenges faced by today's marine researcher seeking to make use of multidisciplinary and sometimes unfamiliar data, the data manager responsible for its stewardship, and the thousands of organisations and institutions around the world tasked with providing access to the vast volumes of data needed to support this increasingly global approach to marine research.

  12. Suburban wildlife: Lessons, challenges, and opportunities

    USGS Publications Warehouse

    DeStefano, S.; Deblinger, R.D.; Miller, C.

    2005-01-01

    The United States, as well as most developed and many developing nations worldwide, is becoming increasingly urban and suburban.Although urban, suburban, and commercial development account for less than one percent to just over 20% of land use among states, 50-90% of the residents of those states can be classified as urban or suburban dwellers. The population of the U.S. as a whole has risen from being > 95% rural in the 1790s to about 80% urban-suburban today. With these changes in land use and demographic patterns come changes in values and attitudes; many urbanites and suburbanites view wildlife and nature differently than rural residents. These are among the challenges faced by wildlife biologists and natural resource managers in a rapidly urbanizing world. In 2003, we convened a symposium to discuss issues related to suburban wildlife. The papers presented in this special issue of Urban Ecosystems address the lessons learned from the early and recently rapidly expanding literature, the challenges we face today, and the opportunities that can help deal with what is one of the biggest challenges to conservation in a modernizing world. ?? 2005 Springer Science + Business Media, Inc.

  13. Revisiting Modernization Theory in Sub-Saharan Africa: The Relationship Between Industrialization and Democratization

    DTIC Science & Technology

    2012-06-01

    per capita and gross domestic product. Literacy is a function of educational opportunity and quality such that people may communicate and acquire...Private capitalists do, however, face the challenges of a largely agricultural and/or informal labor force with lower education, skills and literacy rates... information is estimated to average 1 hour per response, including the time for reviewing instruction , searching existing data sources, gathering and

  14. The rationale for fundamental research in space biology - Introduction and background

    NASA Technical Reports Server (NTRS)

    Halstead, T. W.; Krauss, R. W.

    1992-01-01

    An overview is presented of the concept and development of SSF and the unique opportunities offered by SSF to take advantage of the greater space, the increased power, and especially the long duration of the station for a cascade of innovative experiments in fundamental science. It is emphasized that this space environment will provide new dimensions for approaching some of the most challenging problems still facing modern biology.

  15. If Sport's the Solution Then What's the Problem? The Social Significance of Sport in the Moral Governing of "Good" and "Healthy" Citizens in Sweden, 1922-1998

    ERIC Educational Resources Information Center

    Österlind, Malin; Wright, Jan

    2014-01-01

    All over the westernised world, sport has been promoted as a "solution" to many of the social "problems" and challenges that face modern societies. This study draw on Foucault's concept of governmentality to examine the ways in which Swedish Government Official Reports on sport, from 1922 to 1998, define social problems and…

  16. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Germain, Shawn

    Nuclear Power Plant (NPP) refueling outages create some of the most challenging activities the utilities face in both tracking and coordinating thousands of activities in a short period of time. Other challenges, including nuclear safety concerns arising from atypical system configurations and resource allocation issues, can create delays and schedule overruns, driving up outage costs. Today the majority of the outage communication is done using processes that do not take advantage of advances in modern technologies that enable enhanced communication, collaboration and information sharing. Some of the common practices include: runners that deliver paper-based requests for approval, radios, telephones, desktopmore » computers, daily schedule printouts, and static whiteboards that are used to display information. Many gains have been made to reduce the challenges facing outage coordinators; however; new opportunities can be realized by utilizing modern technological advancements in communication and information tools that can enhance the collective situational awareness of plant personnel leading to improved decision-making. Ongoing research as part of the Light Water Reactor Sustainability Program (LWRS) has been targeting NPP outage improvement. As part of this research, various applications of collaborative software have been demonstrated through pilot project utility partnerships. Collaboration software can be utilized as part of the larger concept of Computer-Supported Cooperative Work (CSCW). Collaborative software can be used for emergent issue resolution, Outage Control Center (OCC) displays, and schedule monitoring. Use of collaboration software enables outage staff and subject matter experts (SMEs) to view and update critical outage information from any location on site or off.« less

  17. An abridged photographic history of organ transplantation.

    PubMed

    Marino, Ignazio R; Cirillo, Claudia

    2014-03-01

    Organ transplantation is one of the most remarkable therapeutic advances in modern medicine; it started as an experiment and has become a life-saving practice. We briefly describe the major milestones of this multidisciplinary clinical science, the challenges that it still faces, and we consider the crucial contribution that its example could set for other medical fields. A review of the literature was conducted and a selection of images was made to complete a brief history of organ transplantation, with a particular focus on liver transplantation. The largest problem affecting organ transplantation today is the shortage of organs. Attention should be given to preserving the peculiar high ethical value that characterizes the very nature of organ transplantation. Methods successfully adopted by organ transplantation during the past 60 years can inspire promising fields, such as stem cell research, and provide useful tools to face the ethical challenges posed by scientific discoveries.

  18. Uncertainty in macroeconomic policy-making: art or science?

    PubMed

    Aikman, David; Barrett, Philip; Kapadia, Sujit; King, Mervyn; Proudman, James; Taylor, Tim; de Weymarn, Iain; Yates, Tony

    2011-12-13

    Uncertainty is pervasive in economic policy-making. Modern economies share similarities with other complex systems in their unpredictability. But economic systems also differ from those in the natural sciences because outcomes are affected by the state of beliefs of the systems' participants. The dynamics of beliefs and how they interact with economic outcomes can be rich and unpredictable. This paper relates these ideas to the recent crisis, which has reminded us that we need a financial system that is resilient in the face of the unpredictable and extreme. It also highlights how such uncertainty puts a premium on sound communication strategies by policy-makers. This creates challenges in informing others about the uncertainties in the economy, and how policy is set in the face of those uncertainties. We show how the Bank of England tries to deal with some of these challenges in its communications about monetary policy.

  19. Modeling crowdsourcing as collective problem solving

    NASA Astrophysics Data System (ADS)

    Guazzini, Andrea; Vilone, Daniele; Donati, Camillo; Nardi, Annalisa; Levnajić, Zoran

    2015-11-01

    Crowdsourcing is a process of accumulating the ideas, thoughts or information from many independent participants, with aim to find the best solution for a given challenge. Modern information technologies allow for massive number of subjects to be involved in a more or less spontaneous way. Still, the full potentials of crowdsourcing are yet to be reached. We introduce a modeling framework through which we study the effectiveness of crowdsourcing in relation to the level of collectivism in facing the problem. Our findings reveal an intricate relationship between the number of participants and the difficulty of the problem, indicating the optimal size of the crowdsourced group. We discuss our results in the context of modern utilization of crowdsourcing.

  20. Constructing a philosophy of chiropractic: evolving worldviews and postmodern core().

    PubMed

    Senzon, Simon A

    2011-12-01

    The purpose of this article is to explore the postmodern, postrational, and postconventional core of DD Palmer's self-sense and philosophy. DD Palmer's self and philosophy can be viewed as a reaction to the self of modernity and its challenges of a fracture between mind and body, spirit, and nature. It is argued that Palmer's solution to these vexing problems facing the modern self was to use postrational and postconventional logic to overcome the dualisms. His philosophy resonates with similar postrational approaches, most notably, the German idealist Schelling. It is argued that Palmer was one of the first postrational individuals in America and that chiropractic was an attempt at the first postrational health profession.

  1. The Social Functions of Iranian Education: An Historical Survey Related to the Current Political Crisis. 1979 World Education Monograph Series, Number Two.

    ERIC Educational Resources Information Center

    Woolman, David C.

    Although the Shah of Iran should be admired for his efforts to use education to deal with formidable social challenges, his goal of producing a modern state in a single generation was unrealistic. Entrenched traditional values and unpredicted economic changes such as the need in 1977 to slow down Iran's rate of growth in the face of runaway…

  2. Information Technology: Department of Veterans Affairs Faces Ongoing Management Challenges

    DTIC Science & Technology

    2011-05-11

    developing joint IT capabilities for the James A. Lovell Federal Health Care Center ( FHCC ) in North Chicago, Illinois. The FHCC is to be the first VA/DOD...solutions, and department officials did not determine whether the IT capabilities developed for the FHCC could or would be implemented at other VA...DOD’s decision to focus on developing VLER, modernizing their separate electronic health record systems, and developing IT capabilities for FHCC

  3. Ontogeny of the maxilla in Neanderthals and their ancestors

    PubMed Central

    Lacruz, Rodrigo S.; Bromage, Timothy G.; O'Higgins, Paul; Arsuaga, Juan-Luis; Stringer, Chris; Godinho, Ricardo Miguel; Warshaw, Johanna; Martínez, Ignacio; Gracia-Tellez, Ana; de Castro, José María Bermúdez; Carbonell, Eudald

    2015-01-01

    Neanderthals had large and projecting (prognathic) faces similar to those of their putative ancestors from Sima de los Huesos (SH) and different from the retracted modern human face. When such differences arose during development and the morphogenetic modifications involved are unknown. We show that maxillary growth remodelling (bone formation and resorption) of the Devil's Tower (Gibraltar 2) and La Quina 18 Neanderthals and four SH hominins, all sub-adults, show extensive bone deposition, whereas in modern humans extensive osteoclastic bone resorption is found in the same regions. This morphogenetic difference is evident by ∼5 years of age. Modern human faces are distinct from those of the Neanderthal and SH fossils in part because their postnatal growth processes differ markedly. The growth remodelling identified in these fossil hominins is shared with Australopithecus and early Homo but not with modern humans suggesting that the modern human face is developmentally derived. PMID:26639346

  4. Ontogeny of the maxilla in Neanderthals and their ancestors.

    PubMed

    Lacruz, Rodrigo S; Bromage, Timothy G; O'Higgins, Paul; Arsuaga, Juan-Luis; Stringer, Chris; Godinho, Ricardo Miguel; Warshaw, Johanna; Martínez, Ignacio; Gracia-Tellez, Ana; de Castro, José María Bermúdez; Carbonell, Eudald

    2015-12-07

    Neanderthals had large and projecting (prognathic) faces similar to those of their putative ancestors from Sima de los Huesos (SH) and different from the retracted modern human face. When such differences arose during development and the morphogenetic modifications involved are unknown. We show that maxillary growth remodelling (bone formation and resorption) of the Devil's Tower (Gibraltar 2) and La Quina 18 Neanderthals and four SH hominins, all sub-adults, show extensive bone deposition, whereas in modern humans extensive osteoclastic bone resorption is found in the same regions. This morphogenetic difference is evident by ∼5 years of age. Modern human faces are distinct from those of the Neanderthal and SH fossils in part because their postnatal growth processes differ markedly. The growth remodelling identified in these fossil hominins is shared with Australopithecus and early Homo but not with modern humans suggesting that the modern human face is developmentally derived.

  5. Supporting research sites in resource-limited settings: Challenges in implementing IT infrastructure

    PubMed Central

    Whalen, Christopher; Donnell, Deborah; Tartakovsky, Michael

    2014-01-01

    As Information and Communication Technology infrastructure becomes more reliable, new methods of Electronic Data Capture (EDC), datamarts/Data warehouses, and mobile computing provide platforms for rapid coordination of international research projects and multisite studies. However, despite the increasing availability of internet connectivity and communication systems in remote regions of the world, there are still significant obstacles. Sites with poor infrastructure face serious challenges participating in modern clinical and basic research, particularly that relying on EDC and internet communication technologies. This report discusses our experiences in supporting research in resource-limited settings (RLS). We describe examples of the practical and ethical/regulatory challenges raised by use of these newer technologies for data collection in multisite clinical studies. PMID:24321986

  6. Supporting research sites in resource-limited settings: challenges in implementing information technology infrastructure.

    PubMed

    Whalen, Christopher J; Donnell, Deborah; Tartakovsky, Michael

    2014-01-01

    As information and communication technology infrastructure becomes more reliable, new methods of electronic data capture, data marts/data warehouses, and mobile computing provide platforms for rapid coordination of international research projects and multisite studies. However, despite the increasing availability of Internet connectivity and communication systems in remote regions of the world, there are still significant obstacles. Sites with poor infrastructure face serious challenges participating in modern clinical and basic research, particularly that relying on electronic data capture and Internet communication technologies. This report discusses our experiences in supporting research in resource-limited settings. We describe examples of the practical and ethical/regulatory challenges raised by the use of these newer technologies for data collection in multisite clinical studies.

  7. Establishing conversation spaces in hastily formed networks: the worst fire in modern Swedish history.

    PubMed

    Lundberg, Jonas; Törnqvist, Eva K; Nadjm-Tehrani, Simin

    2014-10-01

    In presenting examples from the most extensive and demanding fire in modern Swedish history, this paper describes challenges facing hastily formed networks in exceptional situations. Two concepts that have been used in the analysis of the socio-technical systems that make up a response are conversation space and sensemaking. This paper argues that a framework designed to promote understanding of the sensemaking process must take into consideration the time and the location at which an individual is engaged in an event. In hastily formed networks, location is partly mediated through physical systems that form conversation spaces of players and their interaction practices. This paper identifies and discusses four challenges to the formation of shared conversation spaces. It is based on the case study of the 2006 Bodträskfors forest fire in Sweden and draws on the experiences of organised volunteers and firefighters who participated in a hastily formed network created to combat the fire. © 2014 The Author(s). Disasters © Overseas Development Institute, 2014.

  8. Constructing a philosophy of chiropractic: evolving worldviews and postmodern core☆

    PubMed Central

    Senzon, Simon A.

    2011-01-01

    Objective The purpose of this article is to explore the postmodern, postrational, and postconventional core of DD Palmer's self-sense and philosophy. Discussion DD Palmer's self and philosophy can be viewed as a reaction to the self of modernity and its challenges of a fracture between mind and body, spirit, and nature. It is argued that Palmer's solution to these vexing problems facing the modern self was to use postrational and postconventional logic to overcome the dualisms. His philosophy resonates with similar postrational approaches, most notably, the German idealist Schelling. Conclusion It is argued that Palmer was one of the first postrational individuals in America and that chiropractic was an attempt at the first postrational health profession. PMID:22693480

  9. Future challenges for vection research: definitions, functional significance, measures, and neural bases

    PubMed Central

    Palmisano, Stephen; Allison, Robert S.; Schira, Mark M.; Barry, Robert J.

    2015-01-01

    This paper discusses four major challenges facing modern vection research. Challenge 1 (Defining Vection) outlines the different ways that vection has been defined in the literature and discusses their theoretical and experimental ramifications. The term vection is most often used to refer to visual illusions of self-motion induced in stationary observers (by moving, or simulating the motion of, the surrounding environment). However, vection is increasingly being used to also refer to non-visual illusions of self-motion, visually mediated self-motion perceptions, and even general subjective experiences (i.e., “feelings”) of self-motion. The common thread in all of these definitions is the conscious subjective experience of self-motion. Thus, Challenge 2 (Significance of Vection) tackles the crucial issue of whether such conscious experiences actually serve functional roles during self-motion (e.g., in terms of controlling or guiding the self-motion). After more than 100 years of vection research there has been surprisingly little investigation into its functional significance. Challenge 3 (Vection Measures) discusses the difficulties with existing subjective self-report measures of vection (particularly in the context of contemporary research), and proposes several more objective measures of vection based on recent empirical findings. Finally, Challenge 4 (Neural Basis) reviews the recent neuroimaging literature examining the neural basis of vection and discusses the hurdles still facing these investigations. PMID:25774143

  10. A perspective on the future public health: an integrative and ecological framework.

    PubMed

    Hanlon, Phil; Carlisle, Sandra; Hannah, Margaret; Lyon, Andrew; Reilly, David

    2012-11-01

    Modernity has brought health and social benefits to many societies, not least through the insights of science and technology. Yet, modernity has also been associated with a number of cultural characteristics, such as materialism, individualism, consumerism and an addiction to continuing economic growth, that seem potentially harmful to health and well-being and inimical to social equity. There is an emerging body of evidence that suggests that, in the affluent world, some of our most intractable contemporary health problems are, in fact, the product of modernity. This suggests that the tools of modernity (its science and its technology) are ill suited to finding solutions. This poses a problem for public health, as this discipline is itself a product of modernity and thus appears ill equipped to deal with the conditions and challenges of a rapidly changing and unstable world, one where the very sustainability of human society is now in question. This paper argues that a new paradigm for the future public health is needed. It presents an integrative, ecological framework as a starting point from which public health might grasp the opportunities for change inherent in the 'modern' threats we face. It suggests a number of features that will need to underpin such a paradigm shift in thinking and practice. However, as this paper is written from the perspective of an affluent, developed society (albeit from a perspective that is explicitly critical of the goals, trends and values that seem to characterise such societies), other voices from other places need to be heard. We hope that others will want to engage with our arguments and suggestions, whether to challenge and refute these, or to further their development.

  11. Lighting: a driver of the sustainable revolution

    NASA Astrophysics Data System (ADS)

    Verhaar, Harry

    2018-04-01

    Some of the most important things in life are taken for granted, and nowhere is this truer than with light. In this article, we will look at some important milestones marking light's path from human evolution to sustainable revolution, challenges facing the modern lighting industry as well as the world we live in, and what the future promises. In a sense, a new revolution is at hand. It would be hard to overestimate the fundamental importance of light as it shapes virtually everything we sense and experience.

  12. Face Values: The Use of Sensitive Error Correction to Address Adolescents' "Face" Issues in the Modern Languages Classroom

    ERIC Educational Resources Information Center

    Crichton, Hazel; Templeton, Brian; Valdera, Francisco

    2017-01-01

    Anxiety about "performing" in a foreign language in front of classmates may inhibit learners' contributions in the modern languages class through fear of embarrassment over possible error production. The issue of "face", perceived social standing in the eyes of others, presents a sensitive matter for young adolescents…

  13. An insight into burns in a developing country: a Sri Lankan experience.

    PubMed

    Lau, Y S

    2006-10-01

    Burn injuries represent a diverse and varied challenge to medical and paramedical staff. The management of burns and their sequelae in a well-equipped, modern burns unit remains demanding despite advances in surgical techniques and development of tissue-engineered biomaterials; in a developing country, these difficulties are amplified many times. Sri Lanka has a high incidence of burn-related injuries annually due to a combination of adverse social, economic and cultural factors. The management of burn injuries remains a formidable public health problem. The epidemiology of burns, challenges faced in their management and effective strategies specific to Sri Lanka, such as the Safe Bottle Lamp campaign, are highlighted in this paper.

  14. We really need to talk: adapting FDA processes to rapid change.

    PubMed

    Lykken, Sara

    2013-01-01

    The rapidly evolving realm of modern commerce strains traditional regulatory paradigms. This paper traces the historical evolution of FDA crisis-response regulation and provides examples of ways in which the definitions and procedures resulting from that past continue to be challenged by new products as market entrants, some in good faith and others not, take actions that create disconnects between actual product and marketing controls and those that consumers might expect. The paper then explores some of the techniques used by other federal agencies that have faced similar challenges in environments characterized by rapid innovation, and draws from this analysis suggestions for improvement of the FDA's warning letter system.

  15. Divorcing Strain Classification from Species Names.

    PubMed

    Baltrus, David A

    2016-06-01

    Confusion about strain classification and nomenclature permeates modern microbiology. Although taxonomists have traditionally acted as gatekeepers of order, the numbers of, and speed at which, new strains are identified has outpaced the opportunity for professional classification for many lineages. Furthermore, the growth of bioinformatics and database-fueled investigations have placed metadata curation in the hands of researchers with little taxonomic experience. Here I describe practical challenges facing modern microbial taxonomy, provide an overview of complexities of classification for environmentally ubiquitous taxa like Pseudomonas syringae, and emphasize that classification can be independent of nomenclature. A move toward implementation of relational classification schemes based on inherent properties of whole genomes could provide sorely needed continuity in how strains are referenced across manuscripts and data sets. Copyright © 2016 Elsevier Ltd. All rights reserved.

  16. Trust, nostalgia and narrative accounts of blood banking in England in the 21st century.

    PubMed

    Wynne Busby, Helen

    2010-07-01

    Historically, cultural accounts and descriptions of blood banking in Britain have been associated with notions of altruism, national solidarity and imagined community. While these ideals have continued to be influential, the business of procuring and supplying blood has become increasingly complex. Drawing on interview data with donors in one blood centre in England, this article reports that these donors tend not to acknowledge the complex dynamics of production and exchange in modern blood systems. This, it is argued, is congruent with nostalgic narratives in both popular and official accounts of blood services, which tend to bracket these important changes. A shift to a more open institutional narrative about modern blood services is advocated, as blood services face current and future challenges.

  17. The leadership principles of Dr. Martin Luther King, Jr. and their relevance to surgery.

    PubMed

    Brunicardi, F Charles; Cotton, Ronald T; Cole, George W; Martinez, George

    2007-01-01

    In order to face the challenges in healthcare this century, it is essential that surgeons understand modern leadership principles. One of the greatest leaders in history was Dr. Martin Luther King, Jr., who provides a shining example of level-5 leadership for us to study. The study of leadership principles of great leaders can provide us with practical methods of conflict resolution as well as inspiration to keep us engaged and focused. As leaders of the medical community, we face numerous challenges, including discovering and implementing new treatments for disease, providing care for the indigent, overcoming educational challenges such as incorporating the ACGME Core Competencies into our surgical training and promoting diversity in education. Achieving these goals is often hindered by the environment in which we labor-nearly 50 million are uninsured, the rising cost of medical care is currently at 16% of the GNP, and reimbursement rates are falling-which makes the practice of surgery a significant challenge. Effective leadership will be paramount in achieving these goals. In this editorial, which summarizes a presentation given to the Surgical Section of the annual National Medical Association meeting, five important leadership principles that are important for surgeons have been selected and related to the outstanding leadership of Dr. Martin Luther King, Jr.

  18. Foundational Report Series. Advanced Distribution management Systems for Grid Modernization (Importance of DMS for Distribution Grid Modernization)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wang, Jianhui

    2015-09-01

    Grid modernization is transforming the operation and management of electric distribution systems from manual, paper-driven business processes to electronic, computer-assisted decisionmaking. At the center of this business transformation is the distribution management system (DMS), which provides a foundation from which optimal levels of performance can be achieved in an increasingly complex business and operating environment. Electric distribution utilities are facing many new challenges that are dramatically increasing the complexity of operating and managing the electric distribution system: growing customer expectations for service reliability and power quality, pressure to achieve better efficiency and utilization of existing distribution system assets, and reductionmore » of greenhouse gas emissions by accommodating high penetration levels of distributed generating resources powered by renewable energy sources (wind, solar, etc.). Recent “storm of the century” events in the northeastern United States and the lengthy power outages and customer hardships that followed have greatly elevated the need to make power delivery systems more resilient to major storm events and to provide a more effective electric utility response during such regional power grid emergencies. Despite these newly emerging challenges for electric distribution system operators, only a small percentage of electric utilities have actually implemented a DMS. This paper discusses reasons why a DMS is needed and why the DMS may emerge as a mission-critical system that will soon be considered essential as electric utilities roll out their grid modernization strategies.« less

  19. Deep learning and face recognition: the state of the art

    NASA Astrophysics Data System (ADS)

    Balaban, Stephen

    2015-05-01

    Deep Neural Networks (DNNs) have established themselves as a dominant technique in machine learning. DNNs have been top performers on a wide variety of tasks including image classification, speech recognition, and face recognition.1-3 Convolutional neural networks (CNNs) have been used in nearly all of the top performing methods on the Labeled Faces in the Wild (LFW) dataset.3-6 In this talk and accompanying paper, I attempt to provide a review and summary of the deep learning techniques used in the state-of-the-art. In addition, I highlight the need for both larger and more challenging public datasets to benchmark these systems. Despite the ability of DNNs and autoencoders to perform unsupervised feature learning, modern facial recognition pipelines still require domain specific engineering in the form of re-alignment. For example, in Facebook's recent DeepFace paper, a 3D "frontalization" step lies at the beginning of the pipeline. This step creates a 3D face model for the incoming image and then uses a series of affine transformations of the fiducial points to "frontalize" the image. This step enables the DeepFace system to use a neural network architecture with locally connected layers without weight sharing as opposed to standard convolutional layers.6 Deep learning techniques combined with large datasets have allowed research groups to surpass human level performance on the LFW dataset.3, 5 The high accuracy (99.63% for FaceNet at the time of publishing) and utilization of outside data (hundreds of millions of images in the case of Google's FaceNet) suggest that current face verification benchmarks such as LFW may not be challenging enough, nor provide enough data, for current techniques.3, 5 There exist a variety of organizations with mobile photo sharing applications that would be capable of releasing a very large scale and highly diverse dataset of facial images captured on mobile devices. Such an "ImageNet for Face Recognition" would likely receive a warm welcome from researchers and practitioners alike.

  20. Bioreactor Engineering of Stem Cell Environments

    PubMed Central

    Tandon, Nina; Marolt, Darja; Cimetta, Elisa; Vunjak-Novakovic, Gordana

    2013-01-01

    Stem cells hold promise to revolutionize modern medicine by development of new therapies, disease models and drug screening systems. Standard cell culture systems have limited biological relevance because they do not recapitulate the complex 3-dimensional interactions and biophysical cues that characterize the in vivo environment. In this review, we discuss the current advances in engineering stem cell environments using novel biomaterials and bioreactor technologies. We also reflect on the challenges the field is currently facing with regard to translation of stem cell based therapies into the clinic. PMID:23531529

  1. Experiences of Families Transmitting Values in a Rapidly Changing Society: Implications for Family Therapists.

    PubMed

    Akyil, Yudum; Prouty, Anne; Blanchard, Amy; Lyness, Kevin

    2016-06-01

    Intergenerational value transmission affects parent-child relationships and necessitates constant negotiation in families. Families with adolescents from rapidly changing societies face unique challenges in balancing the traditional collectivistic family values that promote harmony with emerging values that promote autonomy. Using modern Turkey as an example of such a culture, the authors examine the transmission process in families that hold more traditional and collectivistic values than their adolescent children. Special consideration is given to generational and cultural differences in the autonomy and relatedness dimensions. © 2015 Family Process Institute.

  2. [The problems of antihypertensive balneotherapy].

    PubMed

    Vladimirskiĭ, E V; Fil'tsagina, T N

    2013-01-01

    This review is devoted to the challenging problems of balneotherapeutics, such as the mechanisms of antihypertensive balneotherapy and its optimization. The experience of the authors with the practical application of chloride - sodium, iodine - bromide, and hydrogen sulfide mineral baths is analysed in comparison with the literature data. The role, dosage regimen, and duration of balneotherapeutic treatment as well as the effectiveness of its combination with medicamental therapy are considered. The authors hope that the discussion of these issues will be conducive to the solution of problems currently facing modern antihypertensive balneotherapy.

  3. Multidisciplinary lung cancer meetings: improving the practice of radiation oncology and facing future challenges.

    PubMed

    Campbell, Belinda A; Ball, David; Mornex, Françoise

    2015-02-01

    Clinical guidelines widely recognize the importance of multidisciplinary meetings (MDM) in the optimal care of lung cancer patients. The published literature suggest that dedicated Lung Cancer MDM lead to increased treatment utilization rates and improved survival outcomes for patients with lung cancer. For radiation oncologists, Lung Cancer MDM have been proven to support evidence-based practice and improve the utilization of radiotherapy. Lung Cancer MDM also allow for education and promotion of specialty radiotherapy services. The fast pace of modern medicine is also presenting new challenges for the multidisciplinary lung cancer team, and technological advances are likely to lead to new changes in the structure of traditional Lung Cancer MDM. © 2015 Asian Pacific Society of Respirology.

  4. Philosophy in medical education: a means of protecting mental health.

    PubMed

    Keller, Eric J

    2014-08-01

    This study sought to identify and examine less commonly discussed challenges to positive mental health faced by medical students, residents, and physicians with hopes of improving current efforts to protect the mental health of these groups. Additionally, this work aimed to suggest an innovative means of preventing poor mental health during medical education. Literature on medical student, resident, and physician mental health was carefully reviewed and a number of psychiatrists who treat physician-patients were interviewed. The culture of medicine, medical training, common physician psychology and identity, and conflicting professional expectations all seem to contribute to poor mental health among medical students, residents, and physicians. Many current efforts may be more successful by better addressing the negative effects of these characteristics of modern medicine. Programs aimed at promoting healthy mental lifestyles during medical education should continue to be developed and supported to mitigate the deleterious effects of the challenging environment of modern medicine. To improve these efforts, educators may consider incorporating philosophical discussions on meaning and fulfillment in life between medical students and faculty. Through medical school faculty members sharing and living out their own healthy outlooks on life, students may emulate these habits and the culture of medicine may become less challenging for positive mental health.

  5. Lifestyle modification in the management of the metabolic syndrome: achievements and challenges

    PubMed Central

    Grave, Riccardo Dalle; Calugi, Simona; Centis, Elena; Marzocchi, Rebecca; Ghoch, Marwan El; Marchesini, Giulio

    2010-01-01

    Lifestyle modification based on behavior therapy is the most important and effective strategy to manage the metabolic syndrome. Modern lifestyle modification therapy combines specific recommendations on diet and exercise with behavioral and cognitive strategies. The intervention may be delivered face-to-face or in groups, or in groups combined with individual sessions. The main challenge of treatment is helping patients maintain healthy behavior changes in the long term. In the last few years, several strategies have been evaluated to improve the long-term effect of lifestyle modification. Promising results have been achieved by combining lifestyle modification with pharmacotherapy, using meals replacement, setting higher physical activity goals, and long-term care. The key role of cognitive processes in the success/failure of weight loss and maintenance suggests that new cognitive procedures and strategies should be included in the traditional lifestyle modification interventions, in order to help patients build a mind-set favoring long-term lifestyle changes. These new strategies raise optimistic expectations for an effective treatment of metabolic syndrome with lifestyle modifications, provided public health programs to change the environment where patients live support them. PMID:21437107

  6. Infrastructure and the Virtual Observatory

    NASA Astrophysics Data System (ADS)

    Dowler, P.; Gaudet, S.; Schade, D.

    2011-07-01

    The modern data center is faced with architectural and software engineering challenges that grow along with the challenges facing observatories: massive data flow, distributed computing environments, and distributed teams collaborating on large and small projects. By using VO standards as key components of the infrastructure, projects can take advantage of a decade of intellectual investment by the IVOA community. By their nature, these standards are proven and tested designs that already exist. Adopting VO standards saves considerable design effort, allows projects to take advantage of open-source software and test suites to speed development, and enables the use of third party tools that understand the VO protocols. The evolving CADC architecture now makes heavy use of VO standards. We show examples of how these standards may be used directly, coupled with non-VO standards, or extended with custom capabilities to solve real problems and provide value to our users. In the end, we use VO services as major parts of the core infrastructure to reduce cost rather than as an extra layer with additional cost and we can deliver more general purpose and robust services to our user community.

  7. The leadership principles of Dr. Martin Luther King, Jr. and their relevance to surgery.

    PubMed Central

    Brunicardi, F. Charles; Cotton, Ronald T.; Cole, George W.; Martinez, George

    2007-01-01

    In order to face the challenges in healthcare this century, it is essential that surgeons understand modern leadership principles. One of the greatest leaders in history was Dr. Martin Luther King, Jr., who provides a shining example of level-5 leadership for us to study. The study of leadership principles of great leaders can provide us with practical methods of conflict resolution as well as inspiration to keep us engaged and focused. As leaders of the medical community, we face numerous challenges, including discovering and implementing new treatments for disease, providing care for the indigent, overcoming educational challenges such as incorporating the ACGME Core Competencies into our surgical training and promoting diversity in education. Achieving these goals is often hindered by the environment in which we labor-nearly 50 million are uninsured, the rising cost of medical care is currently at 16% of the GNP, and reimbursement rates are falling-which makes the practice of surgery a significant challenge. Effective leadership will be paramount in achieving these goals. In this editorial, which summarizes a presentation given to the Surgical Section of the annual National Medical Association meeting, five important leadership principles that are important for surgeons have been selected and related to the outstanding leadership of Dr. Martin Luther King, Jr. Images Figure 1 Figure 2 Figure 3 Figure 4 Figure 5 Figure 6 PMID:17304963

  8. Entrepreneurship within General Aviation

    NASA Technical Reports Server (NTRS)

    Ullmann, Brian M.

    1995-01-01

    Many modern economic theories place great importance upon entrepreneurship in the economy. Some see the entrepreneur as the individual who bears risk of operating a business in the face of uncertainty about future conditions and who is rewarded through profits and losses. The 20th century economist Joseph Schumpter saw the entrepreneur as the medium by which advancing technology is incorporated into society as businesses seek competitive advantages through more efficient product development processes. Due to the importance that capitalistic systems place upon entrepreneurship, it has become a well studied subject with many texts to discuss how entrepreneurs can succeed in modern society. Many entrepreneuring and business management courses go so far as to discuss the characteristic phases and prominent challenges that fledgling companies face in their efforts to bring a new product into a competitive market. However, even with all of these aids, start-up companies fail at an enormous rate. Indeed, the odds of shepherding a new company through the travails of becoming a well established company (as measured by the ability to reach Initial Public Offering (IPO)) have been estimated to be six in 1,000,000. Each niche industry has characteristic challenges which act as barriers to entry for new products into that industry. Thus, the applicability of broad generalizations is subject to limitations within niche markets. This paper will discuss entrepreneurship as it relates to general aviation. The goals of this paper will be to: introduce general aviation; discuss the details of marrying entrepreneurship with general aviation; and present a sample business plan which would characterize a possible entrepreneurial venture.

  9. The fundamental managerial challenges in the role of a contemporary district nurse: A discussion.

    PubMed

    McComiskey, Florence

    2017-10-02

    This article examines some of the fundamental challenges facing the district nurse in delivery of the managerial aspects of her role in contemporary practice. It discusses the personal attributes that are essential for this role to ensure safe, effective and compassionate leadership and management. The communication skills and ethos underpinning collaborative multidiscilplinary team work and person-centred care are discussed. Issues that compromise positive and productive team working are identified, and strategies dealing with conflict and also change management are debated. These factors are interrelated with the everyday demands of caseload management, the development of educational needs to meet the demands of increased complexity in care needs, and the place of technology in modern health care. It is evidenced that sustained organisational support for this role is more important than ever, due to increasing demand and decreasing capacity. Potential solutions to these challenges are offered to assist the contemporary district nurse.

  10. 3D and 4D Bioprinting of the Myocardium: Current Approaches, Challenges, and Future Prospects

    PubMed Central

    Ong, Chin Siang; Nam, Lucy; Ong, Kingsfield; Krishnan, Aravind; Huang, Chen Yu; Fukunishi, Takuma

    2018-01-01

    3D and 4D bioprinting of the heart are exciting notions in the modern era. However, myocardial bioprinting has proven to be challenging. This review outlines the methods, materials, cell types, issues, challenges, and future prospects in myocardial bioprinting. Advances in 3D bioprinting technology have significantly improved the manufacturing process. While scaffolds have traditionally been utilized, 3D bioprinters, which do not require scaffolds, are increasingly being employed. Improved understanding of the cardiac cellular composition and multiple strategies to tackle the issues of vascularization and viability had led to progress in this field. In vivo studies utilizing small animal models have been promising. 4D bioprinting is a new concept that has potential to advance the field of 3D bioprinting further by incorporating the fourth dimension of time. Clinical translation will require multidisciplinary collaboration to tackle the pertinent issues facing this field. PMID:29850546

  11. Technologies for Interactive Learning and Assessment Content Development

    ERIC Educational Resources Information Center

    Gusev, Marjan; Ristov, Sasko; Armenski, Goce

    2016-01-01

    Recent technology trends evolved the student assessment from traditional ones ("pen-and-paper" and "face-to-face") to modern e-Assessment system. These modern approaches allow the teachers to conduct and evaluate an exam with huge number of students in a short period of time. Even more important, both the teacher and the…

  12. Raising the social yield of research: challenge facing biotechnology.

    PubMed

    Grimaud, J A

    2001-12-01

    The biological revolution is the latest in a series of scientific revolutions that have ushered in a new era in physics, chemistry, industry, and composite materials. The latest instruments of life - bioengineering for and by the living - challenge mankind with a number of fundamental questions, while offering an unprecedented series of opportunities. Alternative biotechnologies, biological agriculture for the environment, genomics applied to preventive medicine, genetic engineering are just a few of the benefits mankind may reap from bioengineering. Modern society demands more knowledge, and it is up to public authorities to invest in outreach programs to make public the latest scientific activities and findings. In the case of biotechnologies, it is particularly true that the product of research is not complete until its benefits are returned to society.

  13. A review of smart homes- present state and future challenges.

    PubMed

    Chan, Marie; Estève, Daniel; Escriba, Christophe; Campo, Eric

    2008-07-01

    In the era of information technology, the elderly and disabled can be monitored with numerous intelligent devices. Sensors can be implanted into their home for continuous mobility assistance and non-obtrusive disease prevention. Modern sensor-embedded houses, or smart houses, cannot only assist people with reduced physical functions but help resolve the social isolation they face. They are capable of providing assistance without limiting or disturbing the resident's daily routine, giving him or her greater comfort, pleasure, and well-being. This article presents an international selection of leading smart home projects, as well as the associated technologies of wearable/implantable monitoring systems and assistive robotics. The latter are often designed as components of the larger smart home environment. The paper will conclude by discussing future challenges of the domain.

  14. AIRE-Linux

    NASA Astrophysics Data System (ADS)

    Zhou, Jianfeng; Xu, Benda; Peng, Chuan; Yang, Yang; Huo, Zhuoxi

    2015-08-01

    AIRE-Linux is a dedicated Linux system for astronomers. Modern astronomy faces two big challenges: massive observed raw data which covers the whole electromagnetic spectrum, and overmuch professional data processing skill which exceeds personal or even a small team's abilities. AIRE-Linux, which is a specially designed Linux and will be distributed to users by Virtual Machine (VM) images in Open Virtualization Format (OVF), is to help astronomers confront the challenges. Most astronomical software packages, such as IRAF, MIDAS, CASA, Heasoft etc., will be integrated into AIRE-Linux. It is easy for astronomers to configure and customize the system and use what they just need. When incorporated into cloud computing platforms, AIRE-Linux will be able to handle data intensive and computing consuming tasks for astronomers. Currently, a Beta version of AIRE-Linux is ready for download and testing.

  15. Sensor Technologies for Intelligent Transportation Systems

    PubMed Central

    Guerrero-Ibáñez, Juan; Zeadally, Sherali

    2018-01-01

    Modern society faces serious problems with transportation systems, including but not limited to traffic congestion, safety, and pollution. Information communication technologies have gained increasing attention and importance in modern transportation systems. Automotive manufacturers are developing in-vehicle sensors and their applications in different areas including safety, traffic management, and infotainment. Government institutions are implementing roadside infrastructures such as cameras and sensors to collect data about environmental and traffic conditions. By seamlessly integrating vehicles and sensing devices, their sensing and communication capabilities can be leveraged to achieve smart and intelligent transportation systems. We discuss how sensor technology can be integrated with the transportation infrastructure to achieve a sustainable Intelligent Transportation System (ITS) and how safety, traffic control and infotainment applications can benefit from multiple sensors deployed in different elements of an ITS. Finally, we discuss some of the challenges that need to be addressed to enable a fully operational and cooperative ITS environment. PMID:29659524

  16. Sensor Technologies for Intelligent Transportation Systems.

    PubMed

    Guerrero-Ibáñez, Juan; Zeadally, Sherali; Contreras-Castillo, Juan

    2018-04-16

    Modern society faces serious problems with transportation systems, including but not limited to traffic congestion, safety, and pollution. Information communication technologies have gained increasing attention and importance in modern transportation systems. Automotive manufacturers are developing in-vehicle sensors and their applications in different areas including safety, traffic management, and infotainment. Government institutions are implementing roadside infrastructures such as cameras and sensors to collect data about environmental and traffic conditions. By seamlessly integrating vehicles and sensing devices, their sensing and communication capabilities can be leveraged to achieve smart and intelligent transportation systems. We discuss how sensor technology can be integrated with the transportation infrastructure to achieve a sustainable Intelligent Transportation System (ITS) and how safety, traffic control and infotainment applications can benefit from multiple sensors deployed in different elements of an ITS. Finally, we discuss some of the challenges that need to be addressed to enable a fully operational and cooperative ITS environment.

  17. [Quo vadis, modern intensive care medicine? Outdated considerations regarding risks and side effects].

    PubMed

    Duttge, G

    2016-04-01

    Modern intensive care medicine is faced with large challenges which are not solely caused by medical-technical progress, but above all by the demographic and value-related changes of society and its citizens. Thereby, three central problem areas are of particular interest: the fragile effectiveness of a patient's right to self-determination at the end of life, the uncertainties regarding the demarcation of futility, and the question of the influence of economic considerations (rationing) in view of the different levels for the allocation of duties and execution of duties. This article contains the revised version of the lecture from June 18, 2015 on the occasion of the 47th annual joint conference of DGIIN (Deutschen Gesellschaft für Internistische Intensivmedizin und Notfallmedizin) and ÖGIAIN (Österreichischen Gesellschaft für Internistische und Allgemeine Intensivmedizin und Notfallmedizin) on the general subject: "quality and humanity".

  18. Modern Languages and Distance Education: Thirteen Days in the Cloud

    ERIC Educational Resources Information Center

    Dona, Elfe; Stover, Sheri; Broughton, Nancy

    2014-01-01

    This research study documents the journey of two modern language faculty (Spanish and German) from their original beliefs that teaching foreign languages can only be conducted in a face-to-face format to their eventual development of an online class using Web 2.0 technologies to encourage their students' active skills of reading and speaking in…

  19. Bioreactor engineering of stem cell environments.

    PubMed

    Tandon, Nina; Marolt, Darja; Cimetta, Elisa; Vunjak-Novakovic, Gordana

    2013-11-15

    Stem cells hold promise to revolutionize modern medicine by the development of new therapies, disease models and drug screening systems. Standard cell culture systems have limited biological relevance because they do not recapitulate the complex 3-dimensional interactions and biophysical cues that characterize the in vivo environment. In this review, we discuss the current advances in engineering stem cell environments using novel biomaterials and bioreactor technologies. We also reflect on the challenges the field is currently facing with regard to the translation of stem cell based therapies into the clinic. Copyright © 2013 Elsevier Inc. All rights reserved.

  20. The Evolving Surgeon Image.

    PubMed

    Logghe, Heather J; Rouse, Tyler; Beekley, Alec; Aggarwal, Rajesh

    2018-05-01

    The stereotype of the abrasive, technically gifted white male surgeon is ubiquitous among members of the public and the medical profession. Yet modern surgeons are far more diverse and socially adept than the stereotype suggests. While the stereotype is largely a relic of days gone by, it continues to influence patients' expectations and surgeons' interactions with their clinical colleagues. The #ILookLikeASurgeon movement and subsequent #NYerORCoverChallenge demonstrate the changing face of surgery and the roles of social media in resisting the social and cultural force of long-standing stereotypes. © 2018 American Medical Association. All Rights Reserved.

  1. Managing the professional nurse. Part I. The organizational theories.

    PubMed

    McClure, M L

    1984-02-01

    How do employment organizations outside the hospital field deal with issues such as staff productivity, motivation, burnout, and high turnover? In Part I of this two-part article, the author presents an overview of modern management theory and practice, drawn from the literature on organizational behavior. She shows how nursing administrators can use this scholarly foundation to better understand the organizing principles and problems of their departments. In Part II (to be published in March 1984), the author applies these classic and relevant theories to the specific challenges that face the manager of professional nurses.

  2. Engineering innovation to reduce wind power COE

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ammerman, Curtt Nelson

    There are enough wind resources in the US to provide 10 times the electric power we currently use, however wind power only accounts for 2% of our total electricity production. One of the main limitations to wind use is cost. Wind power currently costs 5-to-8 cents per kilowatt-hour, which is more than twice the cost of electricity generated by burning coal. Our Intelligent Wind Turbine LDRD Project is applying LANL's leading-edge engineering expertise in modeling and simulation, experimental validation, and advanced sensing technologies to challenges faced in the design and operation of modern wind turbines.

  3. The redefinition of failure to thrive from a case study perspective.

    PubMed

    Locklin, Maryanne

    2005-01-01

    Explaining failure to thrive (FTT) in dichotomous terms--organic versus non-organic --no longer applies in the context of modern pediatric nursing. FTT has turned out to be much more multifaceted. One infant's story illustrates the complexities and long-term ramifications of a pediatric feeding disorder and the challenges faced by health care professionals and families in their care. The story illustrates how physiologic, sensorimotor, and behavioral issues can all impact a child's inability to gain weight as expected. With greater understanding, pediatric nurses can appreciate their role as members of a multidisciplinary pediatric feeding disorder team.

  4. Medical entomology--back to the future?

    PubMed

    Reisen, William K

    2014-12-01

    Some of problems and challenges facing Medical/Veterinary Entomology are presented from my perspective, focusing on the current millennium. Topics include anthropogenic environmental changes created by population growth, administrative problems hindering science's response to these changes, and some of the scientific discoveries potentially providing solutions. As the title implies, many recent research discoveries have yet to be translated into major changes in control approaches for the major vectorborne public health problems, thereby providing an interesting mix of modern surveillance technology used to track problems and direct historical intervention solutions. Copyright © 2013 Elsevier B.V. All rights reserved.

  5. Finding our way together on the journey to zero.

    PubMed

    Hilliard, Mary Anne

    2012-01-01

    Remember that classic scene from The Wizard of Oz when Dorothy's house is being hurled into the sky and her world and worries are rotating around her in a great tornado? Ever feel that way at work? To be sure, the modern risk manager and safety professional are facing new challenges and expectations: value-based services, mandatory reporting, pay for performance, new compliance standards, and so on. Sometimes it's disorienting, perhaps similar to how Dorothy must have felt when she realized she was not in Kansas anymore. © 2012 American Society for Healthcare Risk Management of the American Hospital Association.

  6. Logistic regression trees for initial selection of interesting loci in case-control studies

    PubMed Central

    Nickolov, Radoslav Z; Milanov, Valentin B

    2007-01-01

    Modern genetic epidemiology faces the challenge of dealing with hundreds of thousands of genetic markers. The selection of a small initial subset of interesting markers for further investigation can greatly facilitate genetic studies. In this contribution we suggest the use of a logistic regression tree algorithm known as logistic tree with unbiased selection. Using the simulated data provided for Genetic Analysis Workshop 15, we show how this algorithm, with incorporation of multifactor dimensionality reduction method, can reduce an initial large pool of markers to a small set that includes the interesting markers with high probability. PMID:18466557

  7. Integrated Aeroservoelastic Optimization: Status and Direction

    NASA Technical Reports Server (NTRS)

    Livne, Eli

    1999-01-01

    The interactions of lightweight flexible airframe structures, steady and unsteady aerodynamics, and wide-bandwidth active controls on modern airplanes lead to considerable multidisciplinary design challenges. More than 25 years of mathematical and numerical methods' development, numerous basic research studies, simulations and wind-tunnel tests of simple models, wind-tunnel tests of complex models of real airplanes, as well as flight tests of actively controlled airplanes, have all contributed to the accumulation of a substantial body of knowledge in the area of aeroservoelasticity. A number of analysis codes, with the capabilities to model real airplane systems under the assumptions of linearity, have been developed. Many tests have been conducted, and results were correlated with analytical predictions. A selective sample of references covering aeroservoelastic testing programs from the 1960s to the early 1980s, as well as more recent wind-tunnel test programs of real or realistic configurations, are included in the References section of this paper. An examination of references 20-29 will reveal that in the course of development (or later modification), of almost every modern airplane with a high authority active control system, there arose a need to face aeroservoelastic problems and aeroservoelastic design challenges.

  8. [The green rural economy: challenges to research and to public health policies posed by agricultural modernization].

    PubMed

    Rigotto, Raquel Maria; Carneiro, Fernando Ferreira; Marinho, Alice Maria Correia Pequeno; Rocha, Mayara Melo; Ferreira, Marcelo José Monteiro; Pessoa, Vanira Matos; Teixeira, Ana Cláudia de Araújo; da Silva, Maria de Lourdes Vicente; Braga, Lara de Queiroz Viana; Teixeira, Maiana Maia

    2012-06-01

    In this paper, we ask ourselves who should, can and has the will to promote health in the rural zone today. The fields of science and public policy were chosen as our primary focus of dialogue conducted from the perspective of the right to health and a healthy environment. Seven lessons emerged: (1) in addition to the surveillance of isolated chemical risks, the relation between agrochemicals and health should be investigated in the context of conservative agricultural modernization; (2) it is mandatory and urgent to discover the health problems related to the use of agrochemicals; (3) the State has been successful in its support of agribusiness, but highly inefficient at enforcing policies to safeguard social rights; (4) sectors of society linked to rural organizations have played an important role in the public policies combating agrochemicals and protecting health; (5) studies must help deconstruct the myths surrounding the Green Revolution model; (6) we are faced with the challenge of contributing to the construction of an emerging scientific paradigm founded on an ethical-political commitment to the most vulnerable social elements; (7) rural communities are creating agro-ecological alternatives for life in semiarid areas.

  9. Strength training for the warfighter.

    PubMed

    Kraemer, William J; Szivak, Tunde K

    2012-07-01

    Optimizing strength training for the warfighter is challenged by past training philosophies that no longer serve the modern warfighter facing the "anaerobic battlefield." Training approaches for integration of strength with other needed physical capabilities have been shown to require a periodization model that has the flexibility for changes and is able to adapt to ever-changing circumstances affecting the quality of workouts. Additionally, sequencing of workouts to limit over-reaching and development of overtraining syndromes that end in loss of duty time and injury are paramount to long-term success. Allowing adequate time for rest and recovery and recognizing the negative influences of extreme exercise programs and excessive endurance training will be vital in moving physical training programs into a more modern perspective as used by elite strength-power anaerobic athletes in sports today. Because the warfighter is an elite athlete, it is time that training approaches that are scientifically based are updated within the military to match the functional demands of modern warfare and are given greater credence and value at the command levels. A needs analysis, development of periodized training modules, and individualization of programs are needed to optimize the strength of the modern warfighter. We now have the knowledge, professional coaches and nonprofit organization certifications with continuing education units, and modern training technology to allow this to happen. Ultimately, it only takes command decisions and implementation to make this possible.

  10. Teaching medical ethics to meet the realities of a changing health care system.

    PubMed

    Millstone, Michael

    2014-06-01

    The changing context of medical practice--bureaucratic, political, or economic--demands that doctors have the knowledge and skills to face these new realities. Such changes impose obstacles on doctors delivering ethical care to vulnerable patient populations. Modern medical ethics education requires a focus upon the knowledge and skills necessary to close the gap between the theory and practice of ethical care. Physicians and doctors-in-training must learn to be morally sensitive to ethical dilemmas on the wards, learn how to make professionally grounded decisions with their patients and other medical providers, and develop the leadership, dedication, and courage to fulfill ethical values in the face of disincentives and bureaucratic challenges. A new core focus of medical ethics education must turn to learning how to put ethics into practice by teaching physicians to realistically negotiate the new institutional maze of 21st-century medicine.

  11. Toleration and the Design of Norms.

    PubMed

    Floridi, Luciano

    2015-10-01

    One of the pressing challenges we face today-in a post-Westphalian order (emergence of the state as the modern, political information agent) and post-Bretton Woods world (emergence of non-state multiagent systems or MASs as "hyperhistorical" players in the global economy and politics)-is how to design the right kind of MAS that can take full advantage of the socio-economic and political progress made so far, while dealing successfully with the new global challenges that are undermining the best legacy of that very progress. This is the topic of the article. In it, I argue that (i) in order to design the right kind of MAS, we need to design the right kind of norms that constitute them; (ii) in order to design the right kind of constitutive norms, we need to identify and adopt the right kind of principles of normative design; (iii) toleration is one of those principles; (iv) unfortunately, its role as a foundation for the design of norms has been undermined by the "paradox of toleration"; (v) however, the paradox can be solved; (vi) so toleration can be re-instated as the right kind of foundational principle for the design of the right kind of norms that can constitute the right kind of MAS that can operate across cultures, societies and states, to help us to tackle the new global challenges facing us.

  12. Patient monitoring in mobile health: opportunities and challenges.

    PubMed

    Mohammadzadeh, Niloofar; Safdari, Reza

    2014-01-01

    In most countries chronic diseases lead to high health care costs and reduced productivity of people in society. The best way to reduce costs of health sector and increase the empowerment of people is prevention of chronic diseases and appropriate health activities management through monitoring of patients. To enjoy the full benefits of E-health, making use of methods and modern technologies is very important. This literature review articles were searched with keywords like Patient monitoring, Mobile Health, and Chronic Disease in Science Direct, Google Scholar and Pub Med databases without regard to the year of publications. Applying remote medical diagnosis and monitoring system based on mobile health systems can help significantly to reduce health care costs, correct performance management particularly in chronic disease management. Also some challenges are in patient monitoring in general and specific aspects like threats to confidentiality and privacy, technology acceptance in general and lack of system interoperability with electronic health records and other IT tools, decrease in face to face communication between doctor and patient, sudden interruptions of telecommunication networks, and device and sensor type in specific aspect. It is obvious identifying the opportunities and challenges of mobile technology and reducing barriers, strengthening the positive points will have a significant role in the appropriate planning and promoting the achievements of the health care systems based on mobile and helps to design a roadmap for improvement of mobile health.

  13. Challenges and Perspectives for Tertiary Level Hospitals in Bolivia: The case of Santa Cruz de La Sierra Department.

    PubMed

    Medici, André

    2015-01-01

    Current legislation transferred public tertiary hospitals in Bolivia from the Municipalities to the Regional Level. However, the Regional Governments are experiencing technical and financial constraints to reform infrastructure, modernize equipment and introduce reforms to allow better governance, management and sustainability of these hospitals. This articles summarizes the recent experience of the Government of Santa Cruz de la Sierra in Bolivia where five tertiary hospitals and blood bank (most of them in precarious working conditions) has been transferred in 2012 from the Municipal Government of Santa Cruz (the capital) to the Regional Government of Santa Cruz. To face the challenges, the Regional Government of Santa Cruz implement several improvements, such as contract new clinical and administrative personal, increases hospital budgetary autonomy, outsource hospitals' auxiliary services, take measures to eliminate waiting lists and make several new investments to modernize and equip the hospitals. The World Bank was contracted to evaluated the future financial sustainability of these investments and to advice the Government to propose changes to increase the hospitals' management performance. The article describes the remaining challenges in these hospitals and the proposals from the World Bank Study. In the area of quality of care, the main challenge is to improve client satisfaction and continuous outcomes monitoring and evaluation according quality standards. In the area of financing, the challenge is how to assure the sustainability of these hospitals with the current level of health financing and the insufficient financial transfers from the National Government. In the area of Governance, reforms to streamline and simplify internal processes need to be introduced in order to establish mechanisms to increase transparency and accountability, allowing the hospital to have a good administration and adequate participation of the main actors in the guidance of the institution.

  14. Vertebrate land invasions-past, present, and future: an introduction to the symposium.

    PubMed

    Ashley-Ross, Miriam A; Hsieh, S Tonia; Gibb, Alice C; Blob, Richard W

    2013-08-01

    The transition from aquatic to terrestrial habitats was a seminal event in vertebrate evolution because it precipitated a sudden radiation of species as new land animals diversified in response to novel physical and biological conditions. However, the first stages of this environmental transition presented numerous challenges to ancestrally aquatic organisms, and necessitated changes in the morphological and physiological mechanisms that underlie most life processes, among them movement, feeding, respiration, and reproduction. How did solutions to these functional challenges evolve? One approach to this question is to examine modern vertebrate species that face analogous demands; just as the first tetrapods lived at the margins of bodies of water and likely moved between water and land regularly, many extant fishes and amphibians use their body systems in both aquatic and terrestrial habitats on a daily basis. Thus, studies of amphibious vertebrates elucidate the functional demands of two very different habitats and clarify our understanding of the initial evolutionary challenges of moving onto land. A complementary approach is to use studies of the fossil record and comparative development to gain new perspectives on form and function of modern amphibious and non-amphibious vertebrate taxa. Based on the synthetic approaches presented in the symposium, it is clear that our understanding of aquatic-to-terrestrial transitions is greatly improved by the reciprocal integration of paleontological and neontological perspectives. In addition, common themes and new insights that emerged from this symposium point to the value of innovative approaches, new model species, and cutting-edge research techniques to elucidate the functional challenges and evolutionary changes associated with vertebrates' invasion of the land.

  15. Developing IT Infrastructure for Rural Hospitals: A Case Study of Benefits and Challenges of Hospital-to-Hospital Partnerships.

    PubMed

    Reddy, Madhu C; Purao, Sandeep; Kelly, Mary

    2008-01-01

    This article presents a study identifying benefits and challenges of a novel hospital-to-hospital information technology (IT) outsourcing partnership (HHP). The partnership is an innovative response to the problem that many smaller, rural hospitals face: to modernize their IT infrastructure in spite of a severe shortage of resources. The investigators studied three rural hospitals that outsourced their IT infrastructure, through an HHP, to a larger, more technologically advanced hospital in the region. The study design was based on purposive sampling and interviews of senior managers from the four hospitals. The results highlight the HHP's benefits and challenges from both the rural hospitals' and vendor hospital's perspectives. The HHP was considered a success: a key outcome was that it has improved the rural hospitals' IT infrastructure at an affordable cost. The investigators discuss key elements for creating a successful HHP and offer preliminary answers to the question of what it takes for an HHP to be successful.

  16. Developing IT Infrastructure for Rural Hospitals: A Case Study of Benefits and Challenges of Hospital-to-Hospital Partnerships

    PubMed Central

    Reddy, Madhu C.; Purao, Sandeep; Kelly, Mary

    2008-01-01

    This article presents a study identifying benefits and challenges of a novel hospital-to-hospital information technology (IT) outsourcing partnership (HHP). The partnership is an innovative response to the problem that many smaller, rural hospitals face: to modernize their IT infrastructure in spite of a severe shortage of resources. The investigators studied three rural hospitals that outsourced their IT infrastructure, through an HHP, to a larger, more technologically advanced hospital in the region. The study design was based on purposive sampling and interviews of senior managers from the four hospitals. The results highlight the HHP's benefits and challenges from both the rural hospitals' and vendor hospital's perspectives. The HHP was considered a success: a key outcome was that it has improved the rural hospitals' IT infrastructure at an affordable cost. The investigators discuss key elements for creating a successful HHP and offer preliminary answers to the question of what it takes for an HHP to be successful. PMID:18436901

  17. On the Performance of an Algebraic MultigridSolver on Multicore Clusters

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Baker, A H; Schulz, M; Yang, U M

    2010-04-29

    Algebraic multigrid (AMG) solvers have proven to be extremely efficient on distributed-memory architectures. However, when executed on modern multicore cluster architectures, we face new challenges that can significantly harm AMG's performance. We discuss our experiences on such an architecture and present a set of techniques that help users to overcome the associated problems, including thread and process pinning and correct memory associations. We have implemented most of the techniques in a MultiCore SUPport library (MCSup), which helps to map OpenMP applications to multicore machines. We present results using both an MPI-only and a hybrid MPI/OpenMP model.

  18. Documenting the Physical Universe:Preserving the Record of SLAC from 1962 to 2005

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Deken, Jean Marie; /SLAC

    2006-03-10

    Since 1905, Albert Einstein's ''miraculous year'', modern physics has advanced explosively. In 2005, the World Year of Physics, a session at the SAA Annual meeting discusses three institutional initiatives--Einstein's collected papers, an international geophysical program, and a research laboratory--to examine how physics and physicists are documented and how that documentation is being collected, preserved, and used. This paper provides a brief introduction to the research laboratory (SLAC), discusses the origins of the SLAC Archives and History Office, its present-day operations, and the present and future challenges it faces in attempting to preserve an accurate historical record of SLAC's activities.

  19. ARPA-E: Innovating Today. Transforming Tomorrow.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rohlfing, Eric; Brown, Kristen; Gerbi, Jennifer

    Innovation and entrepreneurism are integral parts of America’s national fiber and driving forces behind many of the technologies that define our modern lives. It’s this entrepreneurial spirit – in conjunction with world-class institutions and talent – that enable the United States to develop advanced energy technologies that can solve the many challenges we face. Featuring remarks from multiple ARPA-E staff, this video explores how ARPA-E leverages our nation’s resources to help nurture and grow America’s energy innovation community. The video also incorporates footage shot onsite with several ARPA-E awardees who are innovating solutions to transform tomorrow’s energy future.

  20. Social Dynamic of Yogyakarta Citizens in Facing the Uncertainty of Traditional Value and Modernity: The Integrated Value of Social Study

    ERIC Educational Resources Information Center

    Sridiyatmiko, Gunawan

    2016-01-01

    The principal issue of this study is "how does the society dynamic of Yogyakarta in facing the polemic of traditional, modernity, and social study values which can be developed in social study learning at school? The general aim of this study is to find how the society dynamic phenomenon which happened in Yogyakarta mainly in Kraton, Kauman,…

  1. The next generation of command post computing

    NASA Astrophysics Data System (ADS)

    Arnold, Ross D.; Lieb, Aaron J.; Samuel, Jason M.; Burger, Mitchell A.

    2015-05-01

    The future of command post computing demands an innovative new solution to address a variety of challenging operational needs. The Command Post of the Future is the Army's primary command and control decision support system, providing situational awareness and collaborative tools for tactical decision making, planning, and execution management from Corps to Company level. However, as the U.S. Army moves towards a lightweight, fully networked battalion, disconnected operations, thin client architecture and mobile computing become increasingly essential. The Command Post of the Future is not designed to support these challenges in the coming decade. Therefore, research into a hybrid blend of technologies is in progress to address these issues. This research focuses on a new command and control system utilizing the rich collaboration framework afforded by Command Post of the Future coupled with a new user interface consisting of a variety of innovative workspace designs. This new system is called Tactical Applications. This paper details a brief history of command post computing, presents the challenges facing the modern Army, and explores the concepts under consideration for Tactical Applications that meet these challenges in a variety of innovative ways.

  2. Changing societies and four tasks of schooling: Challenges for strongly differentiated educational systems

    NASA Astrophysics Data System (ADS)

    van de Werfhorst, Herman G.

    2014-05-01

    Changing labour markets, increased calls for selection and excellence, and increased diversity and individualisation have repercussions on how educational systems can prepare youth for work, optimise knowledge production, achieve equality of opportunity, and socialise students into active civic engagement. This paper discusses four central tasks of schooling and examines to what extent societal developments challenge education policy to deliver on the tasks at hand. Particular attention is given to the challenges Europe's strongly diversified educational systems are currently facing. Both the Netherlands and Germany, for example, have been offering vocationally-oriented pathways alongside traditional academic higher education for some time. But today's ongoing changes in job descriptions, mainly due to ever-accelerating technological developments, are causing a risk of skills obsolescence which can only be avoided by continuous upskilling and/or reskilling of a sufficiently flexible workforce. Overcoming differences of intelligence as well as differences of diverse socioeconomic, ethnic and linguistic backgrounds by way of education is another challenge, as is fostering "soft" skills and political awareness. This paper investigates the effectiveness of current education systems in preparing citizens for a functioning modern society.

  3. The Role of NOAA's National Data Centers in the Earth and Space Science Infrastructure

    NASA Astrophysics Data System (ADS)

    Fox, C. G.

    2008-12-01

    NOAA's National Data Centers (NNDC) provide access to long-term archives of environmental data from NOAA and other sources. The NNDCs face significant challenges in the volume and complexity of modern data sets. Data volume challenges are being addressed using more capable data archive systems such as the Comprehensive Large Array-Data Stewardship System (CLASS). Challenges in assuring data quality and stewardship are in many ways more challenging. In the past, scientists at the Data Centers could provide reasonable stewardship of data sets in their area of expertise. As staff levels have decreased and data complexity has increased, Data Centers depend on their data providers and user communities to provide high-quality metadata, feedback on data problems and improvements. This relationship requires strong partnerships between the NNDCs and academic, commercial, and international partners, as well as advanced data management and access tools that conform to established international standards when available. The NNDCs are looking to geospatial databases, interactive mapping, web services, and other Application Program Interface approaches to help preserve NNDC data and information and to make it easily available to the scientific community.

  4. Quality assurance of herbal raw materials in supply chain: challenges and opportunities.

    PubMed

    Govindaraghavan, Suresh

    2008-01-01

    The herbal medicine industry is presently adopting modern scientific tools to substantiate the guarantee of efficacy that, in the past, rested only on anecdotal evidence derived from traditional knowledge systems. This is particularly true for the processes of identification of herbal raw materials adopting modern tools for phytochemical fingerprinting. The successful adaptation of available technologies and practices depends on an understanding of the phytochemical complexity and variability innate in biological material. It challenges the "mainstream medicinal mindset" that "tend(s) to reject …. therapies for which mechanisms of action do not fit within Newtonian, biochemical orientation" (Dumoff, 2003). The herbal medicinal industry is independently evolving its own rigid quality assurance and control systems using Good Manufacturing Practice (GMP) and Good Laboratory Practice (GLP) guidelines, but it faces unique difficulties. These include lack of Good Agricultural and Collection Practice (GACP), lack of transparency in the raw material supply chain so as to preclude the use of unsafe practices, problems in the authentication of herbal raw materials, and a general lack of understanding of the need to reduce phytochemical variability in these materials. This paper explores these difficulties and outlines strategies to overcome them, but these strategies will require coordinated international government regulations to be fully effective.

  5. [Changing economic environment of hospitals: management challenges of the 1990s].

    PubMed

    Rotstein, Z; Noy, S; Goldman, B; Shani, M

    1990-12-16

    The modern hospital is an organization which is influenced by the external environment in which it functions. A major relevant area is the economic environment. In recent years the western world has been facing the challenge of rising costs of health care and an increase in their proportion to the gross national product of most countries. Consequently, hospitals as major providers of health care are under pressure from governments and health insurance companies to cut costs and to "produce" more efficiently. Since hospitals worldwide are finding it hard and painful to function in the new environment in which attitudes to hospitals are changing, a potential managerial-economic crisis may be the next phase. How can the hospital adapt to these changes? First, by adopting managerial attitudes and the tools of the business sector. These include: the strategic planning process, hospital operative autonomy, creating medical-economic responsibility centers as departments, cost-accounting for medical procedures, and case-mix budgeting. Management information systems are necessary during the transition. The hospital information system should include functions at the operative level, such as outpatient visits, and admissions and discharges of patients; and also clinical, diagnostic and laboratory procedures related to the patient case-mix. The second level is a management information system which includes salaries of personnel, case-mix budgeting with variance analysis, prices of procedures and epidemiological data. The authors believe that only the managerial approach combining medical and economic disciplines can meet the challenges of the changing modern economic environment.

  6. Eye Carduino: A Car Control System using Eye Movements

    NASA Astrophysics Data System (ADS)

    Kumar, Arjun; Nagaraj, Disha; Louzardo, Joel; Hegde, Rajeshwari

    2011-12-01

    Modern automotive systems are rapidly becoming highly of transportation, but can be a web integrated media centre. This paper explains the implementation of a vehicle control defined and characterized by embedded electronics and software. With new technologies, the vehicle industry is facing new opportunities and also new challenges. Electronics have improved the performance of vehicles and at the same time, new more complex applications are introduced. Examples of high level applications include adaptive cruise control and electronic stability programs (ESP). Further, a modern vehicle does not have to be merely a means using only eye movements. The EyeWriter's native hardware and software work to return the co-ordinates of where the user is looking. These co-ordinates are then used to control the car. A centre-point is defined on the screen. The higher on the screen the user's gaze is, the faster the car will accelerate. Braking is done by looking below centre. Steering is done by looking left and right on the screen.

  7. A Data-Centric Strategy for Modern Biobanking.

    PubMed

    Quinlan, Philip R; Gardner, Stephen; Groves, Martin; Emes, Richard; Garibaldi, Jonathan

    2015-01-01

    Biobanking has been in existence for many decades and over that time has developed significantly. Biobanking originated from a need to collect, store and make available biological samples for a range of research purposes. It has changed as the understanding of biological processes has increased and new sample handling techniques have been developed to ensure samples were fit-for-purpose.As a result of these developments, modern biobanking is now facing two substantial new challenges. Firstly, new research methods such as next generation sequencing can generate datasets that are at an infinitely greater scale and resolution than previous methods. Secondly, as the understanding of diseases increases researchers require a far richer data set about the donors from which the sample originate.To retain a sample-centric strategy in a research environment that is increasingly dictated by data will place a biobank at a significant disadvantage and even result in the samples collected going unused. As a result biobanking is required to change strategic focus from a sample dominated perspective to a data-centric strategy.

  8. Fourth International Conference: Modern Vaccines/Adjuvants Formulation--Impact on Future Development: May 15-17 2013, CHUV, Lausanne, Switzerland.

    PubMed

    Tupin, Emmanuel

    2013-09-01

    On the 15-17th of May 2013, about 120 scientists, postdoctoral fellows and professors representing renowned academic institutes and senior scientists and executives from small biotechs, contract research organizations (CROs) and Big Pharma companies, gathered at the Centre Hospitalier Universitaire Vaudois (CHUV) in Lausanne, Switzerland for the 4th international conference on Modern Vaccines and Adjuvants Formulation. Despite this relative small number, the speakers and attendees covered together a very broad field of expertise. Indeed, experts in microbiology, immunology, biochemistry, formulation, virus and nanoparticle characterization, vaccine production, quality control as well as regulatory professionals attended the conference and were able to present their works and discuss new developments within the field of vaccine and adjuvant development, characterization and approval process. This broad diversity was a highpoint of the conference and allowed for a stimulating environment and underlined the complexity of the challenges that the field currently faces in order to develop better or completely new vaccines and adjuvants.

  9. Sports Education Facing Globalizing Capitalism

    ERIC Educational Resources Information Center

    Gur-Ze'ev, Ilan

    2005-01-01

    From its very beginning sports activity became--already within the framework of the modern nation-building project, establishing national ethos, and constituting effective colonization of the Other--a central element of the effort of the modern system to create, represent, and consume the modern body and soul and to create the healthy-conquering…

  10. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Widergren, Steven E.; Knight, Mark R.; Melton, Ronald B.

    The Interoperability Strategic Vision whitepaper aims to promote a common understanding of the meaning and characteristics of interoperability and to provide a strategy to advance the state of interoperability as applied to integration challenges facing grid modernization. This includes addressing the quality of integrating devices and systems and the discipline to improve the process of successfully integrating these components as business models and information technology improve over time. The strategic vision for interoperability described in this document applies throughout the electric energy generation, delivery, and end-use supply chain. Its scope includes interactive technologies and business processes from bulk energy levelsmore » to lower voltage level equipment and the millions of appliances that are becoming equipped with processing power and communication interfaces. A transformational aspect of a vision for interoperability in the future electric system is the coordinated operation of intelligent devices and systems at the edges of grid infrastructure. This challenge offers an example for addressing interoperability concerns throughout the electric system.« less

  11. Lessons learned: mobile device encryption in the academic medical center.

    PubMed

    Kusche, Kristopher P

    2009-01-01

    The academic medical center is faced with the unique challenge of meeting the multi-faceted needs of both a modern healthcare organization and an academic institution, The need for security to protect patient information must be balanced by the academic freedoms expected in the college setting. The Albany Medical Center, consisting of the Albany Medical College and the Albany Medical Center Hospital, was challenged with implementing a solution that would preserve the availability, integrity and confidentiality of business, patient and research data stored on mobile devices. To solve this problem, Albany Medical Center implemented a mobile encryption suite across the enterprise. Such an implementation comes with complexities, from performance across multiple generations of computers and operating systems, to diversity of application use mode and end user adoption, all of which requires thoughtful policy and standards creation, understanding of regulations, and a willingness and ability to work through such diverse needs.

  12. Mathematical support for surveying measurements in order to obtain the draft tube three-dimensional model

    NASA Astrophysics Data System (ADS)

    Gridan, Maria-Roberta; Herban, Sorin; Grecea, Oana

    2017-07-01

    Nowadays, the engineering companies and contractors are facing challenges never experienced before. They are being charged with - and being held liable for - the health of the structures they create and maintain. To surmount these challenges, engineers need to be able to measure structural movements up to millimetre level accuracy. Accurate and timely information on the status of a structure is highly valuable to engineers. It enables them to compare the real world behaviour of a structure against the design and theoretical models. When empowered by such data, engineers can effectively and cost efficiently measure and maintain the health of vital infrastructure. This paper presents the interpretation of the draft tube topographical measurements in order to obtain its 3D model. Based on the documents made available by the beneficiary and the data obtained in situ, the modernization conclusions were presented.

  13. 48 CFR 1480.903 - Award in the face of challenge.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false Award in the face of challenge. 1480.903 Section 1480.903 Federal Acquisition Regulations System DEPARTMENT OF THE INTERIOR... Award in the face of challenge. (a) Award of a contract in the face of challenge may be made on the...

  14. 48 CFR 1480.903 - Award in the face of challenge.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 5 2013-10-01 2013-10-01 false Award in the face of challenge. 1480.903 Section 1480.903 Federal Acquisition Regulations System DEPARTMENT OF THE INTERIOR... Award in the face of challenge. (a) Award of a contract in the face of challenge may be made on the...

  15. Gendered Obstacles Faced by Historical Women in Physics and Astronomy

    NASA Astrophysics Data System (ADS)

    Jones, Kristen M.

    2007-12-01

    A gender gap still exists in modern science; this is especially evident in the fields of physics and astronomy. The cause of such a gap is the center of debate. Is this discrepancy the result of inherent ability or socialization? Most studies have focused on modern issues and how women are socialized today. The role of historical gender perspectives and social opinions in creating the field of modern science and any discrepancies within it has not yet been explored in depth. This project investigates the obstacles faced by historical women in physics and astronomy that stem from the officialized gender biases that accompanied the establishment of modern science. Such obstacles are both formal and informal. Four women were chosen to span the three hundred year period between the standardization of the field and the modern day: Laura Bassi, Mary Somerville, Lise Meitner, and Jocelyn Bell Burnell. The investigation reveals that formal obstacles significantly decreased over the time period, while informal obstacles eroded more gradually. Obstacles also reflected historical events such as the World Wars and the Enlightenment. Trends in obstacles faced by four prominent women physicists indicate that education, finances, support networks, and social opinion played a large role in determining success in the field. The applicability to modern day physics issues and the gender gap is discussed. Many thanks to the Pathways Scholars Program and the Ronald E. McNair Post-Baccalaureate Achievement Program for funding for this project.

  16. A Case Study in Flight Computer Software Redesign

    NASA Astrophysics Data System (ADS)

    Shimoni, R.; Ben-Zur, Y.

    2004-06-01

    Historically many real-time systems were developed using technologies that are now obsolete. There is a need for upgrading these systems. A good development process is essential to achieve a well-designed software product. We, at MLM, a subsidary of Israel Aircraft Industries, faced a similar situation in the Flight Mission Computer (Main Airborne Computer-MAC) of the SHAVIT launcher. It was necessary to upgrade the computer hardware and we decided to update the software as well. During the last two years, we have designed and implemented and new version of the MAC software, to be run on a new and stronger target platform. We undertook to create a new version of the MAC program using modern software development techniques. The process included Object-Oriented design using a CASE tool suitable for embedded real-time systems. We have partially implemented the ROPES development process. In this article we present the difficulties and challenges we faced in the software development process.

  17. Inhaling Democracy: Cigarette Advertising and Health Education in Post-war West Germany, 1950s–1975

    PubMed Central

    Elliot, Rosemary

    2015-01-01

    In the late 1960s and early 1970s, the West German government was faced with the challenge of addressing a damaging health behaviour, smoking, in the context of an emerging late modern democracy, when the precedent for addressing that behaviour was set in the Nazi past. This paper details the two-pronged approach which the government took: seeking restrictions on cigarette advertising, whilst educating young people to adopt positive health behaviours in the face of pressure to smoke. This approach can be understood in the social and economic context of the time: an economic commitment to the social market economy worked against restrictions on the sale of cigarettes; whilst concerns about past authoritarian structures prompted the health authorities to seek novel ways of addressing smoking, emphasising choice. In a nuanced way, post-war anti-smoking strategies were a response to West Germany's National Socialist past, but more importantly, a signal of an increasingly international outlook. PMID:26217071

  18. David Mechanic: Professional Zombie Hunter.

    PubMed

    Hafferty, Frederic W; Tilburt, Jon

    2016-08-01

    Within the fields of medicine and sociology, the descriptor "profession" (along with its brethren: profession, professionalization, and professionalism) has had a rich etymological history, with terms taking on different meanings at different times-sometimes trespassing into shibboleth and jargon. This etymological journey has co-evolved with the career of David Mechanic to whom this issue of the Journal of Health Politics, Policy and Law is devoted. We exploit a provocative metaphor applied to Mechanic's work on the challenges facing medicine as a profession as a playful exegesis on what we call "profession" to excavate an ensconced and encrusted domain of health jargon operating at the tensive interface of society and modern medical work. Copyright © 2016 by Duke University Press.

  19. [Modern aspects of organization of medical support for the Armed Forces].

    PubMed

    Stavila, A G; Krasavin, K D; Levchenko, V N; Lemeshko, A L; Roenko, A S

    2015-09-01

    The challenges that medical service of the Armed Forces of the Russian Federation faces cannot be solved without a new qualitative approach to military and medical support. In order to create a complete organizational system of the medical support, consisting of united process of material flow management and management of accompanying elements, the. structure of the medical support and its equipment must correspond to performed tasks. The article describes a set of activities that are performed in the system of military-medical support and offers some promising approaches, which are supposed to solve assigned tasks imposed upon the center of pharmacy and medical technology and its interaction with superior body control, maintainable and third party organizations.

  20. Managing the climate commons at the nexus of ecology, behaviour and economics

    NASA Astrophysics Data System (ADS)

    Tavoni, Alessandro; Levin, Simon

    2014-12-01

    Sustainably managing coupled ecological-economic systems requires not only an understanding of the environmental factors that affect them, but also knowledge of the interactions and feedback cycles that operate between resource dynamics and activities attributable to human intervention. The socioeconomic dynamics, in turn, call for an investigation of the behavioural drivers behind human action. We argue that a multidisciplinary approach is needed in order to tackle the increasingly pressing and intertwined environmental challenges faced by modern societies. Academic contributions to climate change policy have been constrained by methodological and terminological differences, so we discuss how programmes aimed at cross-disciplinary education and involvement in governance may help to unlock scholars' potential to propose new solutions.

  1. Leadership in Undergraduate Medical Education: Training Future Physician Leaders.

    PubMed

    Clyne, Brian; Rapoza, Brenda; George, Paul

    2015-09-01

    To confront the challenges facing modern health care, experts and organizations are calling for an increase in physician leadership capabilities. In response to this need, physician leadership programs are proliferating, targeting all levels of experience at all levels of training. Many academic medical centers, major universities, and specialty societies now sponsor physician leadership training programs. To meet this need, The Warren Alpert Medical School of Brown University, as part of its Primary Care-Population Medicine (PC-PM) Program, designed a four-year integrated curriculum, Leadership in Health Care, to engage with leadership topics starting early in the preclinical stages of training. This paper describes the design and implementation of this leadership curriculum for PC-PM students.

  2. Active Learning in a Large General Physics Classroom.

    NASA Astrophysics Data System (ADS)

    Trousil, Rebecca

    2008-04-01

    In 2004, we launched a new calculus-based, introductory physics sequence at Washington University. Designed as an alternative to our traditional lecture-based sequence, the primary objectives for this new course were to actively engage students in the learning process, to significantly strengthen students' conceptual reasoning skills, to help students develop higher level quantitative problem solving skills necessary for analyzing ``real world'' problems, and to integrate modern physics into the curriculum. This talk will describe our approach, using The Six Ideas That Shaped Physics text by Thomas Moore, to creating an active learning environment in large classes as well as share our perspective on key elements for success and challenges that we face in the large class environment.

  3. Evolutionary psychology in the modern world: applications, perspectives, and strategies.

    PubMed

    Roberts, S Craig; van Vugt, Mark; Dunbar, Robin I M

    2012-12-20

    An evolutionary approach is a powerful framework which can bring new perspectives on any aspect of human behavior, to inform and complement those from other disciplines, from psychology and anthropology to economics and politics. Here we argue that insights from evolutionary psychology may be increasingly applied to address practical issues and help alleviate social problems. We outline the promise of this endeavor, and some of the challenges it faces. In doing so, we draw parallels between an applied evolutionary psychology and recent developments in Darwinian medicine, which similarly has the potential to complement conventional approaches. Finally, we describe some promising new directions which are developed in the associated papers accompanying this article.

  4. From Online Student to Online Instructor: Assistive Strategies

    ERIC Educational Resources Information Center

    McKnight, Jodi

    2012-01-01

    With the influx of online learning opportunities, online students and instructors are faced with a variety of challenges. Online students face the same challenges as do face-to-face learners, but by facing them in an online context, the interpretations of those challenges can lead to the success or failure of their overall educational experience.…

  5. Modernization and development: impact on health care decision-making in Uganda.

    PubMed

    Singh, Debra Anne Kaur; Earnest, Jaya; Lample, May

    2015-01-01

    Uganda has faced numerous challenges over the past 50 years from overcoming political conflict and civil unrest, to rapid population growth, to combating the HIV epidemic and ever-growing health needs. Women in Uganda have had a major role to play in the health of families and communities. The researchers' purpose in this study, undertaken in rural Uganda, was to a) identify a people-centered definition of development, b) compare it to the process of modernization, and c) investigate how these processes have changed the role women play in decision-making, in areas directly and indirectly related to their health and that of their families. Twenty-two men and women participated in focus group discussion and completed questionnaires. Based on our analysis of discussions it appears that both modernization and development have impacted health positively and negatively. Key themes distilled from interviews included that modernization has led to the breakdown of families; increased maternal responsibility for children; diminished land and economic resources; and an erosion of cultural values and practices that had previously provided stability for the society. In terms of development, women play an increasing role in decision-making processes in the household and are gaining increasing respect for their expertise in a number of areas, notably health care. We propose a movement of grassroots discourse on modernization. Development, and its effect on health, is necessary if the positive aspects of Ugandan culture and those of similar emerging societies are not to be lost (International Covenant on Economic, Social and Cultural Rights, 1966).

  6. Policies, economic incentives and the adoption of modern irrigation technology in China

    NASA Astrophysics Data System (ADS)

    Cremades, R.; Wang, J.; Morris, J.

    2015-07-01

    The challenges China faces in terms of water availability in the agricultural sector are exacerbated by the sector's low irrigation efficiency. To increase irrigation efficiency, promoting modern irrigation technology has been emphasized by policy makers in the country. The overall goal of this paper is to understand the effect of governmental support and economic incentives on the adoption of modern irrigation technology in China, with a focus on household-based irrigation technology and community-based irrigation technology. Based on a unique data set collected at household and village levels from seven provinces, the results indicated that household-based irrigation technology has become noticeable in almost every Chinese village. In contrast, only about half of Chinese villages have adopted community-based irrigation technology. Despite the relatively high adoption level of household-based irrigation technology at the village level, its actual adoption in crop sown areas was not high, even lower for community-based irrigation technology. The econometric analysis results revealed that governmental support instruments like subsidies and extension services policies have played an important role in promoting the adoption of modern irrigation technology. Strikingly, the present irrigation pricing policy has played a significant but contradictory role in promoting the adoption of different types of modern irrigation technology. Irrigation pricing showed a positive impact on household-based irrigation technology, and a negative impact on community-based irrigation technology, possibly related to the substitution effect that is, the higher rate of adoption of household-based irrigation technology leads to lower incentives for investment in community-based irrigation technology. The paper finally concludes and discusses some policy implications.

  7. Introducing modern technology to promote transparency in health services.

    PubMed

    Islam, Mohammad Shafiqul

    2015-01-01

    Quantitative indicators show that Bangladeshi maternal and child healthcare is progressing satisfactorily. However, healthcare quality is still inadequate. It is hypothesised that modern technology enhances healthcare quality. Therefore, the purpose of this paper is to investigate how modern technology such as electronic record keeping and the internet can contribute to enhancing Bangladeshi healthcare quality. This study also explores how socio-economic and political factors affect the healthcare quality. This paper is based on a qualitative case study involving 68 in-depth interviews with healthcare professionals, elected representatives, local informants and five focus group discussions with healthcare service users to understand technology's effect on health service quality. The study has been conducted in one rural and one urban service organisations to understand how various factors contribute differently to healthcare quality. The findings show that modern technology, such as the internet and electronic devices for record keeping, contribute significantly to enhancing health service transparency, which in turn leads to quality health and family planning services. The findings also show that information and communication technology (ICT) is an effective mechanism for reducing corruption and promoting transparency. However, resource constraints impact adversely on the introduction of technology, which leads to less transparent healthcare. Progress in education and general socio-economic conditions makes it suitable to enhance ICT usage, which could lead to healthcare transparency, but political and bureaucratic factors pose a major challenge to ensure transparency. This paper can be a useful guide for promoting governance and healthcare quality in developing countries including Bangladesh. It analyses the ICT challenges that healthcare staff face when promoting transparent healthcare. This paper provides a deeper understanding of transparency and healthcare quality in an ICT context using empirical data, which has not been explored in Bangladesh. This critical thinking is useful for policy makers and healthcare practitioners for promoting health service quality.

  8. Engineering Background: Modern Formats and Challenges of Conceptual Engineering

    NASA Astrophysics Data System (ADS)

    Khamidullina, A. F.; Kuzmina, M. A.; Khusnutdinova, E. M.; Konakhina, I. A.

    2017-09-01

    This paper describes the analysis of problems and development perspectives of engineering education in our and other countries. Special attention is given to modern formats of education that motivate creative efforts of engineers-to-be as well as issues of conceptual engineering taking the challenges of modernity into account.

  9. Globalisation, Post-Modernity and the State: Comparative Education Facing the Third Millennium.

    ERIC Educational Resources Information Center

    Welch, Anthony R.

    2001-01-01

    Globalization and post-modernity are linked to changes in the nature of late capitalism and crises in the modern state. Neither offers much in practice to the much needed renewal of democracy, including in education. Indeed, both arguably contribute to a trend towards individualism, and a retreat from democratic engagement and visions of the…

  10. Introduction to the Minireview Series on Modern Technologies for In-cell Biochemistry.

    PubMed

    Lutsenko, Svetlana

    2016-02-19

    The last decade has seen enormous progress in the exploration and understanding of the behavior of molecules in their natural cellular environments at increasingly high spatial and temporal resolution. Advances in microscopy and the development of new fluorescent reagents as well as genetic editing techniques have enabled quantitative analysis of protein interactions, intracellular trafficking, metabolic changes, and signaling. Modern biochemistry now faces new and exciting challenges. Can traditionally "in vitro" experiments, e.g. analysis of protein folding and conformational transitions, be done in cells? Can the structure and behavior of endogenous and/or non-tagged recombinant proteins be analyzed and altered within the cell or in cellular compartments? How can molecules and their actions be studied mechanistically in tissues and organs? Is personalized cellular biochemistry a reality? This thematic series summarizes recent studies that illustrate some first steps toward successfully answering these modern biochemical questions. The first minireview focuses on utilization of three-dimensional primary enteroids and organoids for mechanistic studies of intestinal biology with molecular resolution. The second minireview describes application of single chain antibodies (nanobodies) for monitoring and regulating protein dynamics in vitro and in cells. The third minireview highlights advances in using NMR spectroscopy for analysis of protein folding and assembly in cells. © 2016 by The American Society for Biochemistry and Molecular Biology, Inc.

  11. MO-DE-BRA-05: EUTEMPE-RX: Combining E-Learning and Face-To-Face Training to Build Expert Knowledge, Skills and Competences for Medical Physicists in Diagnostic and Interventional Radiology

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bosmans, H; Van Peteghem, N; Creten, S

    Purpose: In 2013, the EURATOM authorities of the European Commission decided to support the Horizon2020 project submission ‘EUTEMPE-RX’ that aimed for a new set of course modules to train medical physicists in diagnostic and interventional radiology to expert level with small group deep learning. Each module would consist of 2 phases: an e-learning and a face-to-face phase, each phase requiring typically 40h of participant time. Methods: The European Federation (EFOMP) and 13 European partners, all of them selected for their excellent scientific and/or educational skills, led the 12 course modules. A quality manual ensured the quality of course content andmore » organization. Educational workshops familiarized the teachers with e-learning techniques and methods for assessment. Content was set in accordance with the EC document RP174 that lists learning outcomes in terms of knowledge, skills and competences (KSCs) for different specialties and levels of medical physics. Surveys for stake holder satisfaction were prepared. Results: Today the course modules are being realized. The modules cover most of the KSCs in RP174 document. Teachers have challenged the participants with unique tasks: case studies in medical physics leadership, Monte Carlo simulation of a complete x-ray imaging chain, development of a task specific QA protocol, compilation of optimization plans, simulation tasks with anthropomorphic breast models, etc. Participants undertook practical sessions in modern hospitals and visited a synchrotron facility, a calibration lab, screening organizations, etc. Feedback form quality surveys was very positive and constructive. A sustainability plan has been worked out. Conclusion: The modules have enabled the participants to develop their KSCs and cope with challenges in medical physics. The sustainability plan will be implemented to continue the unique combined e-learning and face to face training at high level training in diagnostic and interventional radiology also beyond Europe. The EUTEMPE-RX project is funded by the Horizon2020 - EURATOM program of the European Commission.« less

  12. Data Visualization Challenges and Opportunities in User-Oriented Application Development

    NASA Astrophysics Data System (ADS)

    Pilone, D.; Quinn, P.; Mitchell, A. E.; Baynes, K.; Shum, D.

    2015-12-01

    This talk introduces the audience to some of the very real challenges associated with visualizing data from disparate data sources as encountered during the development of real world applications. In addition to the fundamental challenges of dealing with the data and imagery, this talk discusses usability problems encountered while trying to provide interactive and user-friendly visualization tools. At the end of this talk the audience will be aware of some of the pitfalls of data visualization along with tools and techniques to help mitigate them. There are many sources of variable resolution visualizations of science data available to application developers including NASA's Global Imagery Browse Services (GIBS), however integrating and leveraging visualizations in modern applications faces a number of challenges, including: - Varying visualized Earth "tile sizes" resulting in challenges merging disparate sources - Multiple visualization frameworks and toolkits with varying strengths and weaknesses - Global composite imagery vs. imagery matching EOSDIS granule distribution - Challenges visualizing geographically overlapping data with different temporal bounds - User interaction with overlapping or collocated data - Complex data boundaries and shapes combined with multi-orbit data and polar projections - Discovering the availability of visualizations and the specific parameters, color palettes, and configurations used to produce them In addition to discussing the challenges and approaches involved in visualizing disparate data, we will discuss solutions and components we'll be making available as open source to encourage reuse and accelerate application development.

  13. The future of breast cancer systemic therapy: the next 10 years.

    PubMed

    Telli, Melinda L; Sledge, George W

    2015-02-01

    Over the past 50 years, substantial progress has been made in the systemic treatment of early-stage and advanced breast cancer. The use of chemotherapy in the adjuvant and metastatic settings has demonstrated proven efficacy and it has been clearly demonstrated that targeting the estrogen receptor and human growth factor receptor 2 (HER2) is efficacious in early and advanced disease. Despite these advances, vexing clinical challenges remain particularly related to the treatment of triple-negative breast cancer (TNBC; estrogen receptor [ER]-negative, progesterone receptor [PR]-negative, and HER2-negative) where little progress has been made therapeutically in more than a decade. While recurrences of hormone-responsive breast cancer are overall less common, late relapses after cessation of endocrine therapy are a more frequent occurrence in modern times and reflect the problem of underlying tumor dormancy that as yet has not been overcome. Multiple molecular tools are now available to interrogate the biology of breast cancer, though exactly how to make this information meaningful in the clinic has proven challenging, and molecularly driven clinical trials have faced feasibility challenges. In parallel, focus has expanded from tumor to host with the ability to ascertain underlying germline alterations, such as inherited BRCA1 and BRCA2 mutations, which may be responsible for breast cancer carcinogenesis and, importantly, may have implications for treatment. These clinical advances in germline genetics, made possible by both scientific investigation as well as the courts, still face challenges related to increasing encounters with variants of unknown significance and difficulty in predicting risks associated with less well-characterized inherited cancer predisposition syndromes. In this paper, we attempt to predict the next 10 years of breast cancer, in particular focusing on how the past serves as prologue to the future in this disease.

  14. Blood donation practices, motivations and beliefs in Montreal's Black communities: the modern gift under a new light.

    PubMed

    Tran, Nathalie Y L; Charbonneau, Johanne; Valderrama-Benitez, Valeria

    2013-01-01

    Through the conceptual lens of the archaic and modern gift, this study aims to examine perceived limitations and facilitators to increasing blood donations within Black communities in Montreal, Canada. The overall objective is to support blood agencies, such as Héma-Québec, in understanding the challenges and opportunities they face in promoting blood donation among Black communities in pluralistic societies. Thirty-three semi-structured qualitative interviews were conducted with donors and leaders of ethnocultural groups in Montreal: of these, 6 were Héma-Québec employees; 3 were Caribbean blood drive organizers; 14 were leaders of African, Caribbean or Black multiethnic churches and community groups; and finally, 10 were donors, including 2 African, 4 French-speaking Haitian and 4 English-speaking Caribbean. The existence of multiple Black communities in Montreal reflects the various facilitators and obstacles facing Héma-Québec. Caribbean and African communities have their own experiences with regard to blood donation as well as different relationships with the broader Quebec society, both of which have great impact on how they perceive the cause. Questions of trust, of giving to the family and to the community, as well as perceived social exclusion appear to be fundamental issues for our informants. The current participation of groups interested in bettering the lives of those affected by sickle cell anaemia combined with the fact that leaders felt more comfortable donating to someone close to the community suggests that the promotion of blood donation through this angle would be well received. Trust issues, perceived discrimination and social exclusion have structural and historical roots that can only be partly overcome with long-term efforts to increase awareness, develop collaborative partnerships and increase institutional efforts to adapt to the challenges of blood donation from Black citizens.

  15. Significant Problems in FITS Limit Its Use in Modern Astronomical Research

    NASA Astrophysics Data System (ADS)

    Thomas, B.; Jenness, T.; Economou, F.; Greenfield, P.; Hirst, P.; Berry, D. S.; Bray, E. M.; Gray, N.; Muna, D.; Turner, J.; de Val-Borro, M.; Santander-Vela, J.; Shupe, D.; Good, J.; Berriman, G. B.

    2014-05-01

    The Flexible Image Transport System (FITS) standard has been a great boon to astronomy, allowing observatories, scientists, and the public to exchange astronomical information easily. The FITS standard is, however, showing its age. Developed in the late 1970s the FITS authors made a number of implementation choices for the format that, while common at the time, are now seen to limit its utility with modern data. The authors of the FITS standard could not appreciate the challenges which we would be facing today in astronomical computing. Difficulties we now face include, but are not limited to, having to address the need to handle an expanded range of specialized data product types (data models), being more conducive to the networked exchange and storage of data, handling very large datasets and the need to capture significantly more complex and data relationships. There are members of the community today who find some (or all) of these limitations unworkable, and have decided to move ahead with storing data in other formats. This reaction should be taken as a wakeup call to the FITS community to make changes in the FITS standard, or to see its usage fall. In this paper we detail some selected important problems which exist within the FITS standard today. It is not our intention to prescribe specific remedies to these issues; rather, we hope to call attention of the FITS and greater astronomical computing communities to these issues in the hopes that it will spur action to address them.

  16. "Make Your Own Way There": An Agenda for Young People in the Modern Labour Market.

    ERIC Educational Resources Information Center

    Spierings, John

    The problems facing young people in Australia's current labor market and the effectiveness of Australia's educational system in preparing young people for the labor market were examined. Particular attention was paid to the following issues: the reshaping of work in the modern labor market; skill development in the modern labor market; the impact…

  17. The three modern faces of mercury.

    PubMed Central

    Clarkson, Thomas W

    2002-01-01

    The three modern "faces" of mercury are our perceptions of risk from the exposure of billions of people to methyl mercury in fish, mercury vapor from amalgam tooth fillings, and ethyl mercury in the form of thimerosal added as an antiseptic to widely used vaccines. In this article I review human exposure to and the toxicology of each of these three species of mercury. Mechanisms of action are discussed where possible. Key gaps in our current knowledge are identified from the points of view both of risk assessment and of mechanisms of action. PMID:11834460

  18. Constructing a philosophy of chiropractic: evolving worldviews and modern foundation().

    PubMed

    Senzon, Simon A

    2011-12-01

    The purpose of this article is to trace the foundations of DD Palmer's sense of self and philosophy of chiropractic to its sources in modern Western philosophy as well as current metatheories about modernity. DD Palmer's sense of self was indicative of a modern self. A modern self is characterized as a self that developed after the Western Enlightenment and must come to terms with the insights of modernity such as Cartesian dualism, Spinoza's substance, Rousseau's expressivism, and Kant's critiques. It is argued that Palmer's philosophy can be viewed as part of the this tradition alongside his involvement in the 19th century American metaphysical religious culture, which was itself a response to these challenges of the modern self of modernity. Palmer's development of chiropractic and its philosophy was a reaction to the challenges and promises of modernity.

  19. How to manage future groundwater resource of China under climate change and urbanization: An optimal stage investment design from modern portfolio theory.

    PubMed

    Hua, Shanshan; Liang, Jie; Zeng, Guangming; Xu, Min; Zhang, Chang; Yuan, Yujie; Li, Xiaodong; Li, Ping; Liu, Jiayu; Huang, Lu

    2015-11-15

    Groundwater management in China has been facing challenges from both climate change and urbanization and is considered as a national priority nowadays. However, unprecedented uncertainty exists in future scenarios making it difficult to formulate management planning paradigms. In this paper, we apply modern portfolio theory (MPT) to formulate an optimal stage investment of groundwater contamination remediation in China. This approach generates optimal weights of investment to each stage of the groundwater management and helps maximize expected return while minimizing overall risk in the future. We find that the efficient frontier of investment displays an upward-sloping shape in risk-return space. The expected value of groundwater vulnerability index increases from 0.6118 to 0.6230 following with the risk of uncertainty increased from 0.0118 to 0.0297. If management investment is constrained not to exceed certain total cost until 2050 year, the efficient frontier could help decision makers make the most appropriate choice on the trade-off between risk and return. Copyright © 2015 Elsevier Ltd. All rights reserved.

  20. Identification of high-level functional/system requirements for future civil transports

    NASA Technical Reports Server (NTRS)

    Swink, Jay R.; Goins, Richard T.

    1992-01-01

    In order to accommodate the rapid growth in commercial aviation throughout the remainder of this century, the Federal Aviation Administration (FAA) is faced with a formidable challenge to upgrade and/or modernize the National Airspace System (NAS) without compromising safety or efficiency. A recurring theme in both the Aviation System Capital Investment Plan (CIP), which has replaced the NAS Plan, and the new FAA Plan for Research, Engineering, and Development (RE&D) rely on the application of new technologies and a greater use of automation. Identifying the high-level functional and system impacts of such modernization efforts on future civil transport operational requirements, particularly in terms of cockpit functionality and information transfer, was the primary objective of this project. The FAA planning documents for the NAS of the 2005 era and beyond were surveyed; major aircraft functional capabilities and system components required for such an operating environment were identified. A hierarchical structured analysis of the information processing and flows emanating from such functional/system components were conducted and the results documented in graphical form depicting the relationships between functions and systems.

  1. The deep human prehistory of global tropical forests and its relevance for modern conservation.

    PubMed

    Roberts, Patrick; Hunt, Chris; Arroyo-Kalin, Manuel; Evans, Damian; Boivin, Nicole

    2017-08-03

    Significant human impacts on tropical forests have been considered the preserve of recent societies, linked to large-scale deforestation, extensive and intensive agriculture, resource mining, livestock grazing and urban settlement. Cumulative archaeological evidence now demonstrates, however, that Homo sapiens has actively manipulated tropical forest ecologies for at least 45,000 years. It is clear that these millennia of impacts need to be taken into account when studying and conserving tropical forest ecosystems today. Nevertheless, archaeology has so far provided only limited practical insight into contemporary human-tropical forest interactions. Here, we review significant archaeological evidence for the impacts of past hunter-gatherers, agriculturalists and urban settlements on global tropical forests. We compare the challenges faced, as well as the solutions adopted, by these groups with those confronting present-day societies, which also rely on tropical forests for a variety of ecosystem services. We emphasize archaeology's importance not only in promoting natural and cultural heritage in tropical forests, but also in taking an active role to inform modern conservation and policy-making.

  2. Assessment of Institutional and Personnel-Related Challenges Facing Educational Programme for the Mentally Challenged Persons at Kaimosi Special School, Kenya

    ERIC Educational Resources Information Center

    Mmbwanga, Daniel M.; Matemba, Collins K.; Bota, Kennedy N.

    2015-01-01

    The mentally challenged child (MC) can achieve a lot if the right environment and curriculum are designed for him/her. However, the realization of the desirable outcomes faces many challenges. The objective of the study was to examine institutional and personnel-related challenges facing education programs for the MC persons at Kaimosi Special…

  3. Communicating science in social settings.

    PubMed

    Scheufele, Dietram A

    2013-08-20

    This essay examines the societal dynamics surrounding modern science. It first discusses a number of challenges facing any effort to communicate science in social environments: lay publics with varying levels of preparedness for fully understanding new scientific breakthroughs; the deterioration of traditional media infrastructures; and an increasingly complex set of emerging technologies that are surrounded by a host of ethical, legal, and social considerations. Based on this overview, I discuss four areas in which empirical social science helps clarify intuitive but sometimes faulty assumptions about the social-level mechanisms of science communication and outline an agenda for bench and social scientists--driven by current social-scientific research in the field of science communication--to guide more effective communication efforts at the societal level in the future.

  4. Surrogacy in modern obstetric practice.

    PubMed

    Burrell, Celia; Edozien, Leroy C

    2014-10-01

    Surrogacy is rising in profile and prevalence, which means that perinatal care providers face an increasing likelihood of encountering a case in their clinical practice. Rapidly expanding scientific knowledge (for example, fetal programming) and technological advances (for example, prenatal screening and diagnosis) pose challenges in the management of the surrogate mother; in particular, they could exacerbate conflict between the interests of the baby, the surrogate mother, and the intending parent(s). Navigating these often-tranquil-but-sometimes-stormy waters is facilitated if perinatal care providers are aware of the relevant ethical, legal, and service delivery issues. This paper describes the ethical and legal context of surrogacy, and outlines key clinical practice issues in management of the surrogate mother. Copyright © 2014 Elsevier Ltd. All rights reserved.

  5. [Fifty years of psychiatry at the interface between psyche and soma: a SWOT analysis].

    PubMed

    van Houdenhove, B; Luyten, P

    2008-01-01

    During the past 50 years the border area between psychiatry and somatic medicine has undergone remarkable changes. Theories have become better-founded, both psychologically and neurobiologically, research has become more sophisticated, and liaison-psychiatrists and health psychiatrist/behavioural medicine psychologists have played an increasingly active role in this domain. At the beginning of the 21st century modern psychosomatic medicine is facing new challenges; these include how to create a workable diagnostic classification system, how to instruct and educate both health professionals and lay-persons to an adequate level, how to utilize innovative research paradigms without having recourse to reductionism and how to implement in medical practice treatments that are geared to the needs of the individual patient.

  6. Communicating science in social settings

    PubMed Central

    Scheufele, Dietram A.

    2013-01-01

    This essay examines the societal dynamics surrounding modern science. It first discusses a number of challenges facing any effort to communicate science in social environments: lay publics with varying levels of preparedness for fully understanding new scientific breakthroughs; the deterioration of traditional media infrastructures; and an increasingly complex set of emerging technologies that are surrounded by a host of ethical, legal, and social considerations. Based on this overview, I discuss four areas in which empirical social science helps clarify intuitive but sometimes faulty assumptions about the social-level mechanisms of science communication and outline an agenda for bench and social scientists—driven by current social-scientific research in the field of science communication—to guide more effective communication efforts at the societal level in the future. PMID:23940341

  7. 21 cm cosmology in the 21st century.

    PubMed

    Pritchard, Jonathan R; Loeb, Abraham

    2012-08-01

    Imaging the Universe during the first hundreds of millions of years remains one of the exciting challenges facing modern cosmology. Observations of the redshifted 21 cm line of atomic hydrogen offer the potential of opening a new window into this epoch. This will transform our understanding of the formation of the first stars and galaxies and of the thermal history of the Universe. A new generation of radio telescopes is being constructed for this purpose with the first results starting to trickle in. In this review, we detail the physics that governs the 21 cm signal and describe what might be learnt from upcoming observations. We also generalize our discussion to intensity mapping of other atomic and molecular lines.

  8. Cars and Kinetic Energy -- Some Simple Physics with Real-World Relevance

    NASA Astrophysics Data System (ADS)

    Parthasarathy, Raghuveer

    2012-10-01

    Understanding energy usage is crucial to understanding modern civilization, as well as many of the challenges it faces. Energy-related issues also offer real-world examples of important physical concepts, and as such have been the focus of several articles in The Physics Teacher in the past few decades (e.g., Refs. 1-5, noted further below). Here, I illustrate how a basic understanding of kinetic energy—a topic encountered early in any introductory physics course—enables significant insights into the nature of automobile transportation. Specifically, we can accurately predict how much power the average driver in the United States uses, and explain what determines this, without needing to consider any aspects of mechanical engineering or engine design.

  9. Interdisciplinary challenges in the study of power grid resilience and stability and their relation to extreme weather events

    NASA Astrophysics Data System (ADS)

    Heitzig, J.; Fujiwara, N.; Aihara, K.; Kurths, J.

    2014-10-01

    This topical issue collects contributions to the interdisciplinary study of power grid stability in face of increasing volatility of energy production and consumption due to increasing renewable energy infeed and changing climatic conditions. The individual papers focus on different aspects of this field and bring together modern achievements from various disciplines, in particular complex systems science, nonlinear data analysis, control theory, electrical engineering, and climatology. Main topics considered here are prediction and volatility of renewable infeed, modelling and theoretical analysis of power grid topology, dynamics and stability, relationships between stability and complex network topology, and improvements via topological changes or control. Impacts for the design of smart power grids are discussed in detail.

  10. Capital investment strategies in health care systems.

    PubMed

    Reiter, K L; Smith, D G; Wheeler, J R; Rivenson, H L

    2000-01-01

    Capital investment decisions are among the most important decisions made by firms. They determine the firm's capacity for providing services and commit the firm's cash for an extended period of time. Interviews with chief financial officers of leading health care systems reveal capital investment strategies that generally follow the recommendations of modern finance theory. Still, there is substantial variation in capital budgeting techniques, methods of risk adjustment, and the importance of qualitative considerations in investment decision making. There is also variation in delegation of investment decision making to operating units and methods of performance evaluation. Health care systems face the same challenges as other organizations in developing and implementing capital investment strategies that use consistent methods for evaluation of projects that have inconsistent aims and outcomes.

  11. An engineering design approach to systems biology.

    PubMed

    Janes, Kevin A; Chandran, Preethi L; Ford, Roseanne M; Lazzara, Matthew J; Papin, Jason A; Peirce, Shayn M; Saucerman, Jeffrey J; Lauffenburger, Douglas A

    2017-07-17

    Measuring and modeling the integrated behavior of biomolecular-cellular networks is central to systems biology. Over several decades, systems biology has been shaped by quantitative biologists, physicists, mathematicians, and engineers in different ways. However, the basic and applied versions of systems biology are not typically distinguished, which blurs the separate aspirations of the field and its potential for real-world impact. Here, we articulate an engineering approach to systems biology, which applies educational philosophy, engineering design, and predictive models to solve contemporary problems in an age of biomedical Big Data. A concerted effort to train systems bioengineers will provide a versatile workforce capable of tackling the diverse challenges faced by the biotechnological and pharmaceutical sectors in a modern, information-dense economy.

  12. Returning migrant characteristics and labor market demand in Greece.

    PubMed

    Petras, E M; Kousis, M

    1988-01-01

    Immigrants who repatriate bring with them modern work skills which many observers in labor exporting regions describe as a great contribution to the mother country. Using data from 2 samples of Greek repatriates as well as projections of industrial labor force demands in Greece for the 1980s, this article challenges this concept. The authors find that the uneven regional development and stunted industrial growth which pushed these workers abroad are also responsible for the narrowly limited employment options which they face once they repatriate. For the urban repatriate, the market is limited to unemployment, the urban informal sector and scattered jobs, while for the rural repatriate, small-scale agriculture, multiple job holdings and unemployment are the only viable options.

  13. Near Real Time Integration of Satellite and Radar Data for Probabilistic Nearcasting of Severe Weather

    NASA Astrophysics Data System (ADS)

    Pilone, D.; Quinn, P.; Mitchell, A. E.; Baynes, K.; Shum, D.

    2014-12-01

    This talk introduces the audience to some of the very real challenges associated with visualizing data from disparate data sources as encountered during the development of real world applications. In addition to the fundamental challenges of dealing with the data and imagery, this talk discusses usability problems encountered while trying to provide interactive and user-friendly visualization tools. At the end of this talk the audience will be aware of some of the pitfalls of data visualization along with tools and techniques to help mitigate them. There are many sources of variable resolution visualizations of science data available to application developers including NASA's Global Imagery Browse Services (GIBS), however integrating and leveraging visualizations in modern applications faces a number of challenges, including: - Varying visualized Earth "tile sizes" resulting in challenges merging disparate sources - Multiple visualization frameworks and toolkits with varying strengths and weaknesses - Global composite imagery vs. imagery matching EOSDIS granule distribution - Challenges visualizing geographically overlapping data with different temporal bounds - User interaction with overlapping or collocated data - Complex data boundaries and shapes combined with multi-orbit data and polar projections - Discovering the availability of visualizations and the specific parameters, color palettes, and configurations used to produce them In addition to discussing the challenges and approaches involved in visualizing disparate data, we will discuss solutions and components we'll be making available as open source to encourage reuse and accelerate application development.

  14. The Evolution of Teleophthalmology Programs in the United Kingdom: Beyond Diabetic Retinopathy Screening.

    PubMed

    Sim, Dawn A; Mitry, Danny; Alexander, Philip; Mapani, Adam; Goverdhan, Srini; Aslam, Tariq; Tufail, Adnan; Egan, Catherine A; Keane, Pearse A

    2016-02-01

    Modern ophthalmic practice in the United Kingdom is faced by the challenges of an aging population, increasing prevalence of systemic pathologies with ophthalmic manifestations, and emergent treatments that are revolutionary but dependent on timely monitoring and diagnosis. This represents a huge strain not only on diagnostic services but also outpatient management and surveillance capacity. There is an urgent need for newer means of managing this surge in demand and the socioeconomic burden it places on the health care system. Concurrently, there have been exponential increases in computing power, expansions in the strength and ubiquity of communications technologies, and developments in imaging capabilities. Advances in imaging have been not only in terms of resolution, but also in terms of anatomical coverage, allowing new inferences to be made. In spite of this, image analysis techniques are still currently superseded by expert ophthalmologist interpretation. Teleophthalmology is therefore currently perfectly placed to face this urgent and immediate challenge of provision of optimal and expert care to remote and multiple patients over widespread geographical areas. This article reviews teleophthalmology programs currently deployed in the United Kingdom, focusing on diabetic eye care but also discussing glaucoma, emergency eye care, and other retinal diseases. We examined current programs and levels of evidence for their utility, and explored the relationships between screening, teleophthalmology, disease detection, and monitoring before discussing aspects of health economics pertinent to diabetic eye care. The use of teleophthalmology presents an immense opportunity to manage the steadily increasing demand for eye care, but challenges remain in the delivery of practical, viable, and clinically proven solutions. © 2016 Diabetes Technology Society.

  15. The Evolution of Teleophthalmology Programs in the United Kingdom

    PubMed Central

    Sim, Dawn A.; Mitry, Danny; Alexander, Philip; Mapani, Adam; Goverdhan, Srini; Aslam, Tariq; Tufail, Adnan; Egan, Catherine A.; Keane, Pearse A.

    2016-01-01

    Modern ophthalmic practice in the United Kingdom is faced by the challenges of an aging population, increasing prevalence of systemic pathologies with ophthalmic manifestations, and emergent treatments that are revolutionary but dependent on timely monitoring and diagnosis. This represents a huge strain not only on diagnostic services but also outpatient management and surveillance capacity. There is an urgent need for newer means of managing this surge in demand and the socioeconomic burden it places on the health care system. Concurrently, there have been exponential increases in computing power, expansions in the strength and ubiquity of communications technologies, and developments in imaging capabilities. Advances in imaging have been not only in terms of resolution, but also in terms of anatomical coverage, allowing new inferences to be made. In spite of this, image analysis techniques are still currently superseded by expert ophthalmologist interpretation. Teleophthalmology is therefore currently perfectly placed to face this urgent and immediate challenge of provision of optimal and expert care to remote and multiple patients over widespread geographical areas. This article reviews teleophthalmology programs currently deployed in the United Kingdom, focusing on diabetic eye care but also discussing glaucoma, emergency eye care, and other retinal diseases. We examined current programs and levels of evidence for their utility, and explored the relationships between screening, teleophthalmology, disease detection, and monitoring before discussing aspects of health economics pertinent to diabetic eye care. The use of teleophthalmology presents an immense opportunity to manage the steadily increasing demand for eye care, but challenges remain in the delivery of practical, viable, and clinically proven solutions. PMID:26830492

  16. Knowledge and technology transfer to improve the municipal solid waste management system of Durango City, Mexico.

    PubMed

    Valencia-Vázquez, Roberto; Pérez-López, Maria E; Vicencio-de-la-Rosa, María G; Martínez-Prado, María A; Rubio-Hernández, Rubén

    2014-09-01

    As society evolves its welfare level increases, and as a consequence the amount of municipal solid waste increases, imposing great challenges to municipal authorities. In developed countries, municipalities have established integrated management schemes to handle, treat, and dispose of municipal solid waste in an economical and environmentally sound manner. Municipalities of developing and transition countries are not exempted from the challenges involving municipal solid waste handling, but their task is not easy to accomplish since they face budget deficits, lack of knowledge, and deficiencies in infrastructure and equipment. In the northern territory of Mexico, the municipality of Durango is facing the challenge of increased volumes of waste with a lack of adequate facilities and infrastructure. This article analyses the evolution of the municipal solid waste management of Durango city, which includes actions such as proper facilities construction, equipment acquisition, and the implementation of social programmes. The World Bank, offering courses to municipal managers on landfill operation and waste management, promoted the process of knowledge and technology transfer. Thereafter, municipal authorities attended regional and some international workshops on waste management. In addition they followed suggestions of international contractors and equipment dealers with the intention to improve the situation of the waste management of the city. After a 15-year period, transfer of knowledge and technology resulted in a modern municipal solid waste management system in Durango municipality. The actual system did not reach the standard levels of an integrated waste management system, nevertheless, a functional evaluation shows clear indications that municipality actions have put them on the right pathway. © The Author(s) 2014.

  17. Understanding Leadership in Schools Facing Challenging Circumstances: A Chilean Case Study

    ERIC Educational Resources Information Center

    Ahumada, Luis; Galdames, Sergio; Clarke, Simon

    2016-01-01

    During the last 10 years, research into schools facing challenging circumstances has attracted the attention of researchers around the world. The aim of this study was to understand the challenges that school leaders face as they per form their work, the nature of the context in which these challenges arise, the strategies school leaders adopt to…

  18. Transition in Modern Languages from Primary to Secondary School: The Challenge of Change

    ERIC Educational Resources Information Center

    Chambers, Gary

    2014-01-01

    This article reports on in-depth interviews conducted with 12 teachers of modern languages in relation to how they dealt with the challenge of transition from primary to secondary school, with special reference to modern foreign languages. Findings suggest that only one of the 12 secondary schools was well placed to facilitate a smooth transition,…

  19. The Enduring Challenge of Determining Pneumonia Etiology in Children: Considerations for Future Research Priorities

    PubMed Central

    Hammitt, Laura L.; Murdoch, David R.; O’Brien, Katherine L.; Scott, J. Anthony G.

    2017-01-01

    Abstract Pneumonia kills more children each year worldwide than any other disease. Nonetheless, accurately determining the causes of childhood pneumonia has remained elusive. Over the past century, the focus of pneumonia etiology research has shifted from studies of lung aspirates and postmortem specimens intent on identifying pneumococcal disease to studies of multiple specimen types distant from the lung that are tested for multiple pathogens. Some major challenges facing modern pneumonia etiology studies include the use of nonspecific and variable case definitions, poor access to pathologic lung tissue and to specimens from fatal cases, poor diagnostic accuracy of assays (especially when testing nonpulmonary specimens), and the interpretation of results when multiple pathogens are detected in a given individual. The future of childhood pneumonia etiology research will likely require integrating data from complementary approaches, including applications of advanced molecular diagnostics and vaccine probe studies, as well as a renewed emphasis on lung aspirates from radiologically confirmed pneumonia and postmortem examinations. PMID:28575369

  20. Upgrading Laccase Production and Biochemical Properties: Strategies and Challenges.

    PubMed

    Bertrand, Brandt; Martínez-Morales, Fernando; Trejo-Hernández, María R

    2017-07-01

    Improving laccases continues to be crucial in novel biotechnological developments and industrial applications, where they are concerned. This review breaks down and explores the potential of the strategies (conventional and modern) that can be used for laccase enhancement (increased production and upgraded biochemical properties such as stability and catalytic efficiency). The challenges faced with these approaches are briefly discussed. We also shed light on how these strategies merge and give rise to new options and advances in this field of work. Additionally, this article seeks to serve as a guide for students and academic researchers interested in laccases. This document not only gives basic information on laccases, but also provides updated information on the state of the art of various technologies that are used in this line of investigation. It also gives the readers an idea of the areas extensively studied and the areas where there is still much left to be done. © 2017 American Institute of Chemical Engineers Biotechnol. Prog., 33:1015-1034, 2017. © 2017 American Institute of Chemical Engineers.

  1. Peripheral nerve regeneration with conduits: use of vein tubes

    PubMed Central

    Sabongi, Rodrigo Guerra; Fernandes, Marcela; dos Santos, João Baptista Gomes

    2015-01-01

    Treatment of peripheral nerve injuries remains a challenge to modern medicine due to the complexity of the neurobiological nerve regenerating process. There is a greater challenge when the transected nerve ends are not amenable to primary end-to-end tensionless neurorraphy. When facing a segmental nerve defect, great effort has been made to develop an alternative to the autologous nerve graft in order to circumvent morbidity at donor site, such as neuroma formation, scarring and permanent loss of function. Tubolization techniques have been developed to bridge nerve gaps and have been extensively studied in numerous experimental and clinical trials. The use of a conduit intends to act as a vehicle for moderation and modulation of the cellular and molecular ambience for nerve regeneration. Among several conduits, vein tubes were validated for clinical application with improving outcomes over the years. This article aims to address the investigation and treatment of segmental nerve injury and draw the current panorama on the use of vein tubes as an autogenous nerve conduit. PMID:26170802

  2. Peripheral nerve regeneration with conduits: use of vein tubes.

    PubMed

    Sabongi, Rodrigo Guerra; Fernandes, Marcela; Dos Santos, João Baptista Gomes

    2015-04-01

    Treatment of peripheral nerve injuries remains a challenge to modern medicine due to the complexity of the neurobiological nerve regenerating process. There is a greater challenge when the transected nerve ends are not amenable to primary end-to-end tensionless neurorraphy. When facing a segmental nerve defect, great effort has been made to develop an alternative to the autologous nerve graft in order to circumvent morbidity at donor site, such as neuroma formation, scarring and permanent loss of function. Tubolization techniques have been developed to bridge nerve gaps and have been extensively studied in numerous experimental and clinical trials. The use of a conduit intends to act as a vehicle for moderation and modulation of the cellular and molecular ambience for nerve regeneration. Among several conduits, vein tubes were validated for clinical application with improving outcomes over the years. This article aims to address the investigation and treatment of segmental nerve injury and draw the current panorama on the use of vein tubes as an autogenous nerve conduit.

  3. Multilevel water governance and problems of scale: setting the stage for a broader debate.

    PubMed

    Moss, Timothy; Newig, Jens

    2010-07-01

    Environmental governance and management are facing a multiplicity of challenges related to spatial scales and multiple levels of governance. Water management is a field particularly sensitive to issues of scale because the hydrological system with its different scalar levels from small catchments to large river basins plays such a prominent role. It thus exemplifies fundamental issues and dilemmas of scale in modern environmental management and governance. In this introductory article to an Environmental Management special feature on "Multilevel Water Governance: Coping with Problems of Scale," we delineate our understanding of problems of scale and the dimensions of scalar politics that are central to water resource management. We provide an overview of the contributions to this special feature, concluding with a discussion of how scalar research can usefully challenge conventional wisdom on water resource management. We hope that this discussion of water governance stimulates a broader debate and inquiry relating to the scalar dimensions of environmental governance and management in general.

  4. Progress in Multi-Disciplinary Data Life Cycle Management

    NASA Astrophysics Data System (ADS)

    Jung, C.; Gasthuber, M.; Giesler, A.; Hardt, M.; Meyer, J.; Prabhune, A.; Rigoll, F.; Schwarz, K.; Streit, A.

    2015-12-01

    Modern science is most often driven by data. Improvements in state-of-the-art technologies and methods in many scientific disciplines lead not only to increasing data rates, but also to the need to improve or even completely overhaul their data life cycle management. Communities usually face two kinds of challenges: generic ones like federated authorization and authentication infrastructures and data preservation, and ones that are specific to their community and their respective data life cycle. In practice, the specific requirements often hinder the use of generic tools and methods. The German Helmholtz Association project ’’Large-Scale Data Management and Analysis” (LSDMA) addresses both challenges: its five Data Life Cycle Labs (DLCLs) closely collaborate with communities in joint research and development to optimize the communities data life cycle management, while its Data Services Integration Team (DSIT) provides generic data tools and services. We present most recent developments and results from the DLCLs covering communities ranging from heavy ion physics and photon science to high-throughput microscopy, and from DSIT.

  5. Performance Analysis, Design Considerations, and Applications of Extreme-Scale In Situ Infrastructures

    DOE PAGES

    Ayachit, Utkarsh; Bauer, Andrew; Duque, Earl P. N.; ...

    2016-11-01

    A key trend facing extreme-scale computational science is the widening gap between computational and I/O rates, and the challenge that follows is how to best gain insight from simulation data when it is increasingly impractical to save it to persistent storage for subsequent visual exploration and analysis. One approach to this challenge is centered around the idea of in situ processing, where visualization and analysis processing is performed while data is still resident in memory. Our paper examines several key design and performance issues related to the idea of in situ processing at extreme scale on modern platforms: Scalability, overhead,more » performance measurement and analysis, comparison and contrast with a traditional post hoc approach, and interfacing with simulation codes. We illustrate these principles in practice with studies, conducted on large-scale HPC platforms, that include a miniapplication and multiple science application codes, one of which demonstrates in situ methods in use at greater than 1M-way concurrency.« less

  6. Information technology and its role in anaesthesia training and continuing medical education.

    PubMed

    Chu, Larry F; Erlendson, Matthew J; Sun, John S; Clemenson, Anna M; Martin, Paul; Eng, Reuben L

    2012-03-01

    Today's educators are faced with substantial challenges in the use of information technology for anaesthesia training and continuing medical education. Millennial learners have uniquely different learning styles than previous generations of students. These preferences distinctly incorporate the use of digital information technologies and social technologies to support learning. To be effective teachers, modern educators must be familiar with these new information technologies and understand how to use them for medical education. Examples of new information technologies include learning management systems, lecture capture, social media (YouTube, Flickr), social networking (Facebook), Web 2.0, multimedia (video learning triggers and point-of-view video) and mobile computing applications. The information technology challenges for educators in the twenty-first century include: (a) understanding how technology shapes the learning preferences of today's anaesthesia residents, (b) distinguishing between the function and properties of new learning technologies and (c) properly using these learning technologies to enhance the anaesthesia curriculum. Copyright © 2012 Elsevier Ltd. All rights reserved.

  7. Constructing a philosophy of chiropractic: evolving worldviews and modern foundation☆

    PubMed Central

    Senzon, Simon A.

    2011-01-01

    Objective The purpose of this article is to trace the foundations of DD Palmer's sense of self and philosophy of chiropractic to its sources in modern Western philosophy as well as current metatheories about modernity. Discussion DD Palmer's sense of self was indicative of a modern self. A modern self is characterized as a self that developed after the Western Enlightenment and must come to terms with the insights of modernity such as Cartesian dualism, Spinoza's substance, Rousseau's expressivism, and Kant's critiques. It is argued that Palmer's philosophy can be viewed as part of the this tradition alongside his involvement in the 19th century American metaphysical religious culture, which was itself a response to these challenges of the modern self of modernity. Conclusion Palmer's development of chiropractic and its philosophy was a reaction to the challenges and promises of modernity. PMID:22693479

  8. Challenges Facing a Deaf Family Member Concerning a Loved One’s Dying

    PubMed Central

    Kehl, Karen A.; Gartner, Constance M.

    2010-01-01

    Individuals who are Deaf face challenges both similar and unique from those faced by hearing individuals when a family member is dying. This study was guided by the question “What are the challenges faced by a Deaf family member when a loved one is dying?” Methods - This qualitative study is guided by critical theory and an interpretive perspective. Robert, a college-educated older adult who has been Deaf from birth was interviewed in American Sign Language using a death history format. Results – There are challenges for Deaf family members that affect communication with both the dying person and health care professionals. Patient-family communication issues included physical challenges and financial challenges. Lack of cultural competence concerning the Deaf community created challenges communicating with professionals. Decision-making was also a challenge. Conclusions These findings provide a framework for future research concerning the needs of Deaf individuals facing the end of life and provide guidance for clinicians. PMID:19910395

  9. Menstrual Hygiene, Management, and Waste Disposal: Practices and Challenges Faced by Girls/Women of Developing Countries

    PubMed Central

    Kaur, Rajanbir; Kaur, Kanwaljit

    2018-01-01

    Menstruation and menstrual practices still face many social, cultural, and religious restrictions which are a big barrier in the path of menstrual hygiene management. In many parts of the country especially in rural areas girls are not prepared and aware about menstruation so they face many difficulties and challenges at home, schools, and work places. While reviewing literature, we found that little, inaccurate, or incomplete knowledge about menstruation is a great hindrance in the path of personal and menstrual hygiene management. Girls and women have very less or no knowledge about reproductive tract infections caused due to ignorance of personal hygiene during menstruation time. In rural areas, women do not have access to sanitary products or they know very little about the types and method of using them or are unable to afford such products due to high cost. So, they mostly rely on reusable cloth pads which they wash and use again. Needs and requirements of the adolescent girls and women are ignored despite the fact that there are major developments in the area of water and sanitation. Women manage menstruation differently when they are at home or outside; at homes, they dispose of menstrual products in domestic wastes and in public toilets and they flush them in the toilets without knowing the consequences of choking. So, there should be a need to educate and make them aware about the environmental pollution and health hazards associated with them. Implementation of modern techniques like incineration can help to reduce the waste. Also, awareness should be created to emphasize the use of reusable sanitary products or the natural sanitary products made from materials like banana fibre, bamboo fibre, sea sponges, water hyacinth, and so on. PMID:29675047

  10. Menstrual Hygiene, Management, and Waste Disposal: Practices and Challenges Faced by Girls/Women of Developing Countries.

    PubMed

    Kaur, Rajanbir; Kaur, Kanwaljit; Kaur, Rajinder

    2018-01-01

    Menstruation and menstrual practices still face many social, cultural, and religious restrictions which are a big barrier in the path of menstrual hygiene management. In many parts of the country especially in rural areas girls are not prepared and aware about menstruation so they face many difficulties and challenges at home, schools, and work places. While reviewing literature, we found that little, inaccurate, or incomplete knowledge about menstruation is a great hindrance in the path of personal and menstrual hygiene management. Girls and women have very less or no knowledge about reproductive tract infections caused due to ignorance of personal hygiene during menstruation time. In rural areas, women do not have access to sanitary products or they know very little about the types and method of using them or are unable to afford such products due to high cost. So, they mostly rely on reusable cloth pads which they wash and use again. Needs and requirements of the adolescent girls and women are ignored despite the fact that there are major developments in the area of water and sanitation. Women manage menstruation differently when they are at home or outside; at homes, they dispose of menstrual products in domestic wastes and in public toilets and they flush them in the toilets without knowing the consequences of choking. So, there should be a need to educate and make them aware about the environmental pollution and health hazards associated with them. Implementation of modern techniques like incineration can help to reduce the waste. Also, awareness should be created to emphasize the use of reusable sanitary products or the natural sanitary products made from materials like banana fibre, bamboo fibre, sea sponges, water hyacinth, and so on.

  11. A high-power versatile wireless power transfer for biomedical implants.

    PubMed

    Jiang, Hao; Zhang, Jun Min; Liou, Shy Shenq; Fechter, Richard; Hirose, Shinjiro; Harrison, Michael; Roy, Shuvo

    2010-01-01

    Implantable biomedical actuators are highly desired in modern medicine. However, how to power up these biomedical implants remains a challenge since most of them need more than several hundreds mW of power. The air-core based radio-frequency transformer (two face-to-face inductive coils) has been the only non-toxic and non-invasive power source for implants for the last three decades [1]. For various technical constraints, the maximum delivered power is limited by this approach. The highest delivered power reported is 275 mW over 1 cm distance [2]. Also, the delivered power is highly vulnerable to the coils' geometrical arrangement and the electrical property of the medium around them. In this paper, a novel rotating-magnets based wireless power transfer that can deliver ∼10 W over 1 cm is demonstrated. The delivered power is significantly higher than the existing start-of-art. Further, the new method is versatile since there is no need to have the impedance matching networks that are highly susceptible to the operating frequency, the coil arrangement and the environment.

  12. Homeland Security. Management Challenges Facing Federal Leadership

    DTIC Science & Technology

    2002-12-01

    Security Management Challenges Facing Federal Leadership 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT...including attention to management practices and key success factors. HOMELAND SECURITY Management Challenges Facing Federal Leadership www.gao.gov/cgi...significant management and coordination challenges if it is to provide this leadership and be successful in preventing and responding to any future

  13. Romanticism and schizophrenia. Second part: The intimacy hypothesis.

    PubMed

    López-Ibor, Juan J; López-Ibor, María I

    2014-01-01

    In the first part of this article we have analyzed the evidence supporting the recency hypothesis of schizophrenia and also what we can call the intimate nature of the disease. In this part we highlight the role of certain cultural aspects that have been ignored up to now, aspects that are associated with deep changes in the Weltanschauung and systems of beliefs on human nature brought up by the late Modernism, specifically by Romanticism. The description of the main characteristics of Romanticism, starting with the “discovery of intimacy”, leads to the conclusion that the characteristic alteration of subjectivity and ipseity of the disease appears to be a vulnerability factor when somebody has to face the new challenges raise Romanticism. The consideration of Hölderlin’s literary achievements and the deep psychological drama prevailing in them, makes explicit how the late modern human being finds in Romanticism the source of creativity and personal development but also the threat of his or her own destruction. Finally we link our hypothesis with recent genetic perspectives that consider sets of diseases associated to the same gene or genes (diseasome). In any case the process of associating the traits of Late Modernism and Romanticism with the core features of schizophrenia allows to consider the amalgamation of insanity with society, both at a general level an in what concerns individual patients, paving the way for novel therapeutic strategies.

  14. Isotopic and genetic insights into the persistence of the northern fur seal (Callorhinus ursinus) (Invited)

    NASA Astrophysics Data System (ADS)

    Koch, P. L.; Hadly, E. A.; Pinsky, M. L.; Newsome, S. D.

    2010-12-01

    What factors allow some species to survive in the face of climate change, disease, or anthropogenic disturbance? How do species shift their geographic distributions in the face of such challenges? These pressing questions in ecology and conservation biology are difficult to answer when looking solely at modern populations or the recent historical record. We explore these questions through analysis of DNA and the isotopic composition of modern and ancient northern fur seals (NFS, Callorhinus ursinus). The NFS is an eared seal (otariid) that ranges along the north Pacific, where it breeds on offshore islands; by far the largest modern rookeries are on the Pribilof Islands in the Bering Sea. The species shows a high degree of philopatry, and females feed while nursing, wean pups at 4 months, and spend the rest of the year foraging far offshore further south. Archaelogical study reveals that Holocene NFS had numerous breeding colonies from the Channel Islands to the Aleutians. Temperate latitude colonies collapsed in the late Holocene in response to hunting pressures and perhaps, environmental change. The species has recolonized parts of its former range since the 1960s. Despite facing similar threats, other marine mammals have failed to rebound (e.g., Guadalupe fur seals) or have exceptionally low genetic diversity indicating recent and prolonged bottlenecks (e.g., northern elephant seals). Isotopic analyses of sub-fossil growth series indicate that extirpated mid-latitude colonies weaned much later (≥12 months), like all other otariid species that breed at temperate latitudes. As a result, females were tied to rookery sites year-round and had a much-reduced migratory range relative to modern NFS females breeding in the Bering Sea, a result also supported by isotopic analyses. Serial coalescent simulations of ancient and modern DNA reveals that exceptionally high migration rates and Arctic refugia provided resilience to NFS. These traits allowed the species to maintain high levels of genetic diversity even as it lost breeding colonies across its geographic range. Thus the behavioral differences suggested by isotopic analysis result from phenotypic plasticity rather than local adaptation, providing further survival strategies for the species. The detailed paleontological record available for northern fur seals offers an excellent opportunity to examine the genetic and behavioral diversity of a species within and among populations through time. We conclude that general species traits (panmixia, behavioral plasticity, broad geographic range, a secure refuge) can provide long-term resilience to overexploitation, climate change, and other stressors. For example, similar traits may have allowed southern elephant seals to colonize the Antarctic mainland during the middle Holocene, only to collapse back to sub-Antarctic islands with the onset of icy conditions in the latest Holocene. Overall, such knowledge will help to predict future ecosystem changes and to identify species that are most likely to benefit from management interventions such as assisted migration and translocation.

  15. Learning from FITS: Limitations in use in modern astronomical research

    NASA Astrophysics Data System (ADS)

    Thomas, B.; Jenness, T.; Economou, F.; Greenfield, P.; Hirst, P.; Berry, D. S.; Bray, E.; Gray, N.; Muna, D.; Turner, J.; de Val-Borro, M.; Santander-Vela, J.; Shupe, D.; Good, J.; Berriman, G. B.; Kitaeff, S.; Fay, J.; Laurino, O.; Alexov, A.; Landry, W.; Masters, J.; Brazier, A.; Schaaf, R.; Edwards, K.; Redman, R. O.; Marsh, T. R.; Streicher, O.; Norris, P.; Pascual, S.; Davie, M.; Droettboom, M.; Robitaille, T.; Campana, R.; Hagen, A.; Hartogh, P.; Klaes, D.; Craig, M. W.; Homeier, D.

    2015-09-01

    The Flexible Image Transport System (FITS) standard has been a great boon to astronomy, allowing observatories, scientists and the public to exchange astronomical information easily. The FITS standard, however, is showing its age. Developed in the late 1970s, the FITS authors made a number of implementation choices that, while common at the time, are now seen to limit its utility with modern data. The authors of the FITS standard could not anticipate the challenges which we are facing today in astronomical computing. Difficulties we now face include, but are not limited to, addressing the need to handle an expanded range of specialized data product types (data models), being more conducive to the networked exchange and storage of data, handling very large datasets, and capturing significantly more complex metadata and data relationships. There are members of the community today who find some or all of these limitations unworkable, and have decided to move ahead with storing data in other formats. If this fragmentation continues, we risk abandoning the advantages of broad interoperability, and ready archivability, that the FITS format provides for astronomy. In this paper we detail some selected important problems which exist within the FITS standard today. These problems may provide insight into deeper underlying issues which reside in the format and we provide a discussion of some lessons learned. It is not our intention here to prescribe specific remedies to these issues; rather, it is to call attention of the FITS and greater astronomical computing communities to these problems in the hope that it will spur action to address them.

  16. E-Mentoring the Online Doctoral Student from the Dissertation Prospectus through Dissertation Completion

    ERIC Educational Resources Information Center

    Black, Ronald

    2017-01-01

    Faculty who mentor online doctoral candidates face many of the same challenges and opportunities as those mentoring doctoral candidates in traditional, face-to-face modalities. The main difference is that E-Mentoring is based on interacting in the online space rather than interacting face-to-face, which may present challenges for both the…

  17. The role of symbolic capital in stakeholder disputes: decision-making concerning intractable wastes.

    PubMed

    Benn, Suzanne; Jones, Richard

    2009-04-01

    This paper examines almost 30 years of disputation concerning the disposal of the world's largest stockpile of the toxic organochlorine, hexachlorbenzene. It describes the study of a chemicals company in its attempt to manage the disposal of the toxic waste in a collaborative fashion with government, environmentalists and the local community. The study describes the new processes and structures specifically designed to address the decision-making and the issues of stakeholder perception and identity construction which have influenced the outcomes. Decision-making in such disputes is often theorized from the perspective of the emergence of highly individualized and reflexive risk communities and changing modes and expectations of corporate responsibility as a result of detraditionalization. We argue that the stakeholder interaction in this study reflects competing discourses in which corporate actors prioritize the building and maintaining of identity and symbolic capital rather than an active collaboration to solve the ongoing issue of the waste. As well, issues of access to expert knowledge highlight the relationship between conditions of uncertainty, technoscientific expertise and identity. The events of the study highlight the challenges faced by contemporary technoscientific corporations such as chemicals companies as they must deliver on requirements of transparency and openness, while maintaining technoscientific capacity and strong internal identity. We conclude that the study demonstrates the co-existence of social processes of individualization and detraditionalization with quasi-traditions which maintain authority, thus challenging the radical distinctions made in the literature between modernity and late or reflexive modernity.

  18. Turtles: Freshwater

    USGS Publications Warehouse

    Gibbons, J. Whitfield; Lovich, Jeffrey E.; Bowden, R.M.

    2017-01-01

    With their iconic shells, turtles are morphologically distinct in being the only extant or extinct vertebrate animals to have their shoulders and hips inside their rib cages. By the time an asteroid hit the earth 65.5 million years ago, causing the extinction of dinosaurs, turtles were already an ancient lineage that was 70% through their evolutionary history to date. The remarkable evolutionary success of turtles over 220 million years is due to a combination of both conservative and effective life history traits and an essentially unchanging morphology that withstood the test of time. However, the life history traits of many species make them particularly susceptible to overharvest and habitat destruction in the modern world, and a majority of the world’s species face serious conservation challenges with several extinctions documented in modern times. The global plight of turtles is underscored by the fact that the percentage of imperiled species exceeds that of even the critically endangered primates.Freshwater turtles, with over 260 recognized species, have become a focus on a worldwide scale for many conservation issues. This article is a synthesis of a diverse body of information on the general biology of freshwater turtles, with particular emphasis on the extensive research on ecology, life history, and behavior that has been accomplished in the last half century. Much of the research has been applicable to the aforementioned conservation challenges. The studies presented include a combination of laboratory and field experiments and observational studies on this intriguing group of animals.

  19. Mastering the broadband challenge: next-generation SONET in a packet world

    NASA Astrophysics Data System (ADS)

    Farhi, Eyal

    2001-10-01

    The continuing liberalization of the world's telecommunications markets and the progressive convergence of voice, data, video and Internet communication are prompting telecommunication service providers to both expand and enhance their service capabilities. As bandwidth-hungry applications proliferate, and the demand for data and data services grows, the requirement for broadband communications appears to be insatiable. To provide the expected level of service in this environment of rapidly increasing demand, telcos and service providers must invest in an expanded network. However, to remain competitive and profitable, they must also continue to leverage their existing infrastructure investment. This paper will examine the current challenges network operators are facing today with the deployment of broadband technologies as they strive to maintain existing infrastructure investments while providing new services to their customers and developing added value network operations. This paper will explore various broadband technologies (optical/wireless) that operate on the primary SDH/SONET standards, their topologies and inherent benefits, which provide operators with solutions to the broadband challenge. New customer demands, such as high-speed Data transmissions (increased Internet use), coupled with operators' continuous need for network optimization, have thrown a wrench into daily operations. Therefore, the need to modernize existing networks has become paramount.

  20. Symposium on "The challenge of translating nutrition research into public health nutrition". Session 4: Challenges facing the food industry in innovating for health. Regulatory challenges and opportunities for food innovation.

    PubMed

    Binns, Nino

    2009-02-01

    The primary role of the extensive and complex modern food legislation is to protect the consumer. Providing a framework for industry and enabling free trade are secondary aims. In the EU the 2006 Regulation on nutrition and health claims made on foods was adopted in December 2006. This Regulation defines detailed lists of permitted claims with precise conditions, requires foods making claims to meet specific nutrient profiles and requires the submission of a dossier for approval of new health claims. Nutrient profiles and an initial list of existing health claims will not be agreed until January 2009 and January 2010 respectively. The uncertainty about profiles and the initial list of claims as well as the prescriptive nature of the Regulation will have a major impact, some negative but some positive, on food innovation. Worldwide legislation on nutrition and health claims continues to develop. The current paper also provides an outline of some other key pieces of European legislation that affect food innovation. However, currently, all this legislation remains in development and up-to-date information can be sought from the reference material provided.

  1. Shams 1 - Design and operational experiences of the 100MW - 540°C CSP plant in Abu Dhabi

    NASA Astrophysics Data System (ADS)

    Alobaidli, Abdulaziz; Sanz, Borja; Behnke, Klaus; Witt, Thomas; Viereck, Detlef; Schwarz, Mark André

    2017-06-01

    SHAMS 1 ("Shams" means "Sun" in Arabic) Concentrated Solar Power plant is a very successful example of a modern plant, which combines the known configuration of a parabolic trough technology with the well-established power generation technologies operated at 540°C live steam temperature while respecting the specific requirement of the daily starts and shutdowns. In addition to the high live steam temperature challenge and being located in the middle of the desert approx. 120 km south west of the city of Abu Dhabi, the plant has to face, the plant has to fact several atmospheric challenges like the high dust concentration, wind storms, and high ambient temperature. This paper, written jointly by Shams Power Company - the project and operating company and MAN Diesel & Turbo - the steam turbine original manufacturer, describes the challenges in optimizing the design of the steam turbine to fulfill the requirement of fast start up while operating the plant on daily transient pattern for minimum 30 years. It also addresses the several atmospheric challenges and how the project and operating company has overcame them. Finally, the paper gives a snap shot on the operational experience and record of the plant showing that despite the very challenging environment, the budgeted target has been exceeded in the first two years of operation.

  2. But I Don't Understand You: One Faculty's Observations of the Challenges Facing International Healthcare Students

    ERIC Educational Resources Information Center

    DuBose, Cheryl O.

    2017-01-01

    International students face many challenges when pursuing a degree in higher education. Communication and cultural differences are typically cited as the most challenging aspects of any study abroad program. Students attempting to complete a healthcare program face sometimes insurmountable issues, as communication, cultural differences, and…

  3. The Sisters of Mercy in the Crimean War: Lessons for Catholic health care

    PubMed Central

    Paradis, Mary Raphael; Hart, Edith Mary; O’Brien, Mary Judith

    2017-01-01

    In 1856, an appeal went out to nurses in both England and Ireland, and especially to religious nurses, to care for the troops fighting in the Crimean War. The Sisters of Mercy, founded in 1831 by Venerable Catherine McAuley, answered that call. This article describes the enormous challenges the Sisters faced in that mission, which was a test of their nursing skills, flexibility, organizational ability, and their spirit of mercy. The challenges they faced professionally and as religious Sisters, the manner in which they faced those challenges, and their spiritual lives as religious women shaped their ability to give comprehensive care. Some applications are made to the challenges which religious communities and organizations working in health care face in our country at this time. Summary: This article describes the challenges faced by a group of Sisters of Mercy from England and Ireland who volunteered to serve as nurses in the Crimean War from 1856 to 1858. Applications are made to challenges which are faced by religious communities and organizations in the current secular healthcare environment. PMID:28392597

  4. The Sisters of Mercy in the Crimean War: Lessons for Catholic health care.

    PubMed

    Paradis, Mary Raphael; Hart, Edith Mary; O'Brien, Mary Judith

    2017-02-01

    In 1856, an appeal went out to nurses in both England and Ireland, and especially to religious nurses, to care for the troops fighting in the Crimean War. The Sisters of Mercy, founded in 1831 by Venerable Catherine McAuley, answered that call. This article describes the enormous challenges the Sisters faced in that mission, which was a test of their nursing skills, flexibility, organizational ability, and their spirit of mercy. The challenges they faced professionally and as religious Sisters, the manner in which they faced those challenges, and their spiritual lives as religious women shaped their ability to give comprehensive care. Some applications are made to the challenges which religious communities and organizations working in health care face in our country at this time. Summary: This article describes the challenges faced by a group of Sisters of Mercy from England and Ireland who volunteered to serve as nurses in the Crimean War from 1856 to 1858. Applications are made to challenges which are faced by religious communities and organizations in the current secular healthcare environment.

  5. Challenges in Teaching Modern Manufacturing Technologies

    ERIC Educational Resources Information Center

    Ngaile, Gracious; Wang, Jyhwen; Gau, Jenn-Terng

    2015-01-01

    Teaching of manufacturing courses for undergraduate engineering students has become a challenge due to industrial globalisation coupled with influx of new innovations, technologies, customer-driven products. This paper discusses development of a modern manufacturing course taught concurrently in three institutions where students collaborate in…

  6. 77 FR 73112 - Agency Information Collection Activities: Proposed Request and Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-07

    ... respondents give during a personal interview. The respondents are individuals, State and local governments... conducts this legally mandated information collection in field offices via personal contact (face-to-face or telephone interview) using the automated Modernized SSI Claim System (MSSICS). The respondents are...

  7. Pesticides reduce regional biodiversity of stream invertebrates

    PubMed Central

    Beketov, Mikhail A.; Kefford, Ben J.; Schäfer, Ralf B.; Liess, Matthias

    2013-01-01

    The biodiversity crisis is one of the greatest challenges facing humanity, but our understanding of the drivers remains limited. Thus, after decades of studies and regulation efforts, it remains unknown whether to what degree and at what concentrations modern agricultural pesticides cause regional-scale species losses. We analyzed the effects of pesticides on the regional taxa richness of stream invertebrates in Europe (Germany and France) and Australia (southern Victoria). Pesticides caused statistically significant effects on both the species and family richness in both regions, with losses in taxa up to 42% of the recorded taxonomic pools. Furthermore, the effects in Europe were detected at concentrations that current legislation considers environmentally protective. Thus, the current ecological risk assessment of pesticides falls short of protecting biodiversity, and new approaches linking ecology and ecotoxicology are needed. PMID:23776226

  8. Craniofacial embryology and postnatal development of relevant parts of the upper respiratory system.

    PubMed

    Halewyck, S; Louryan, S; Van Der Veken, P; Gordts, F

    2012-01-01

    To compare historical and current knowledge relating to the development of the paranasal sinuses, the nose and face, the Eustachian tube and temporal bones, particularly with respect to chronic inflammation during childhood. Traditional literature data, mainly emanating from text books, were supplemented with information based on a non-structured PubMed search covering the last two decades. Historical knowledge has most often been confirmed, sometimes supplemented and only rarely challenged by present-day studies. Recent studies focus mainly on the clinical application of modern imaging techniques. Interest in the development of relevant parts of the upper respiratory system remains as lively as ever. Imaging techniques with low or absent radiation exposure may give rise to a novel field of research, especially with respect to paediatric rhinosinusitis.

  9. Modern Techniques in Acoustical Signal and Image Processing

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Candy, J V

    2002-04-04

    Acoustical signal processing problems can lead to some complex and intricate techniques to extract the desired information from noisy, sometimes inadequate, measurements. The challenge is to formulate a meaningful strategy that is aimed at performing the processing required even in the face of uncertainties. This strategy can be as simple as a transformation of the measured data to another domain for analysis or as complex as embedding a full-scale propagation model into the processor. The aims of both approaches are the same--to extract the desired information and reject the extraneous, that is, develop a signal processing scheme to achieve thismore » goal. In this paper, we briefly discuss this underlying philosophy from a ''bottom-up'' approach enabling the problem to dictate the solution rather than visa-versa.« less

  10. A Route Towards Sustainability Through Engineered Polymeric Interfaces

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Reeja-Jayan, B; Kovacik, P; Yang, R

    2014-05-30

    Chemical vapor deposition (CVD) of polymer films represent the marriage of two of the most important technological innovations of the modern age. CVD as a mature technology for growing inorganic thin films is already a workhorse technology of the microfabrication industry and easily scalable from bench to plant. The low cost, mechanical flexibility, and varied functionality offered by polymer thin films make them attractive for both macro and micro scale applications. This review article focuses on two energy and resource efficient CVD polymerization methods, initiated Chemical Vapor Deposition (iCVD) and oxidative Chemical Vapor Deposition (oCVD). These solvent-free, substrate independent techniquesmore » engineer multi-scale, multi-functional and conformal polymer thin film surfaces and interfaces for applications that can address the main sustainability challenges faced by the world today.« less

  11. Agroforestry: a refuge for tropical biodiversity?

    PubMed

    Bhagwat, Shonil A; Willis, Katherine J; Birks, H John B; Whittaker, Robert J

    2008-05-01

    As rates of deforestation continue to rise in many parts of the tropics, the international conservation community is faced with the challenge of finding approaches which can reduce deforestation and provide rural livelihoods in addition to conserving biodiversity. Much of modern-day conservation is motivated by a desire to conserve 'pristine nature' in protected areas, while there is growing recognition of the long-term human involvement in forest dynamics and of the importance of conservation outside protected areas. Agroforestry -- intentional management of shade trees with agricultural crops -- has the potential for providing habitats outside formally protected land, connecting nature reserves and alleviating resource-use pressure on conservation areas. Here we examine the role of agroforestry systems in maintaining species diversity and conclude that these systems can play an important role in biodiversity conservation in human-dominated landscapes.

  12. Chinese ethnic meat products: Continuity and development.

    PubMed

    Zeng, Weicai; Wen, Wenting; Deng, Yue; Tian, Yuanyuan; Sun, Honghu; Sun, Qun

    2016-10-01

    With their distinctive sensory characterizations and unique processing technologies, Chinese ethnic meat products possess great potential for development and continuity in modern China's meat industry. Due to the greater demand for meat products and higher quality and safety concerns in economically fast growing China, the development and continuity of ethnic meat products face its own unique challenges. In this review, the classification of typical ethnic products and their characteristics, and the research progress on their quality and processing technologies are discussed. The application of innovative and green technologies to improve the safety and quality of ethnic meat products for greater industrialization and sustainable development is highlighted. Furthermore, the strategy for promoting the production of Chinese ethnic meat products during the next five years is presented. Copyright © 2016 Elsevier Ltd. All rights reserved.

  13. Framework for Architecture Trade Study Using MBSE and Performance Simulation

    NASA Technical Reports Server (NTRS)

    Ryan, Jessica; Sarkani, Shahram; Mazzuchim, Thomas

    2012-01-01

    Increasing complexity in modern systems as well as cost and schedule constraints require a new paradigm of system engineering to fulfill stakeholder needs. Challenges facing efficient trade studies include poor tool interoperability, lack of simulation coordination (design parameters) and requirements flowdown. A recent trend toward Model Based System Engineering (MBSE) includes flexible architecture definition, program documentation, requirements traceability and system engineering reuse. As a new domain MBSE still lacks governing standards and commonly accepted frameworks. This paper proposes a framework for efficient architecture definition using MBSE in conjunction with Domain Specific simulation to evaluate trade studies. A general framework is provided followed with a specific example including a method for designing a trade study, defining candidate architectures, planning simulations to fulfill requirements and finally a weighted decision analysis to optimize system objectives.

  14. Personalized Comments on Challenges and Opportunities in Kidney Disease Therapeutics: The Glom-NExT Symposium.

    PubMed

    Greka, Anna; Gibson, Deb; Mundel, Peter; Demetri, George; Hildebrandt, Friedhelm; Pollak, Martin; Florez, Jose

    2016-11-01

    In the face of ever-increasing incidence and prevalence of kidney disease worldwide, the unmet need for new treatments is unprecedented. Precision medicine is defined as the use of modern technologies to identify mechanisms of diseases in individual patients, and thus deploy treatment using tailored, targeted approaches, in the hopes of avoiding unnecessary toxicities and complications. Is there a place for kidney disease therapeutics in this space? If so, what is required to make significant progress toward precision nephrology? To answer these critical questions, we present a series of personalized comments corresponding to the responses offered to these very questions during the Inaugural Glom-NExT Symposium held at Harvard Medical School on October 23, 2014, a national meeting focused exclusively on kidney disease therapeutics. Copyright © 2016.

  15. Contribution of Crop Models to Adaptation in Wheat.

    PubMed

    Chenu, Karine; Porter, John Roy; Martre, Pierre; Basso, Bruno; Chapman, Scott Cameron; Ewert, Frank; Bindi, Marco; Asseng, Senthold

    2017-06-01

    With world population growing quickly, agriculture needs to produce more with fewer inputs while being environmentally friendly. In a context of changing environments, crop models are useful tools to simulate crop yields. Wheat (Triticum spp.) crop models have been evolving since the 1960s to translate processes related to crop growth and development into mathematical equations. These have been used over decades for agronomic purposes, and have more recently incorporated advances in the modeling of environmental footprints, biotic constraints, trait and gene effects, climate change impact, and the upscaling of global change impacts. This review outlines the potential and limitations of modern wheat crop models in assisting agronomists, breeders, and policymakers to address the current and future challenges facing agriculture. Copyright © 2017 Elsevier Ltd. All rights reserved.

  16. Community in Online Higher Education: Challenges and Opportunities

    ERIC Educational Resources Information Center

    Arasaratnam-Smith, Lily A.; Northcote, Maria

    2017-01-01

    Exploring the challenges and opportunities associated with the concepts of community and communication in online higher education, this paper reconsiders the intention to replicate face-to-face learning and teaching strategies in online learning environments. Rather than beginning with the assumption that face-to-face education is the prototype…

  17. Amicicide: The Problem of Friendly Fire in Modern War

    DTIC Science & Technology

    1982-12-01

    episodes of the Korean War was the stubborn, defense of the British 29th Brigade along the Imjin River north of Seoul in April 1951.67 Faced by a...antiaircraft fire over Paestum beach in Italy. Amicicide: The Problem of Friendly Fire in Modern War by Lieutenant Colonel Charles R. Shrader, U.S...Data Shrader, Charles R. Amicieide: the problem of friendly fire in modern war . (Research survey/Combat Studies Institute, U.S. Army Command and

  18. Classic Conversational Norms in Modern Computer-Mediated Collaboration

    ERIC Educational Resources Information Center

    Oeberst, Aileen; Moskaliuk, Johannes

    2016-01-01

    This paper examines whether conversational norms that have been observed for face-to-face communication also hold in the context of a specific type of computer-mediated communication: collaboration (such as in Wikipedia). Specifically, we tested adherence to Grice's (1975) maxim of relation--the implicit demand to contribute information that is…

  19. Strategy and Finance in Higher Education. Surviving the '90s.

    ERIC Educational Resources Information Center

    Massy, William F., Ed.; Meyerson, Joel W., Ed.

    This book provides a new look at educational management in the face of mounting financial pressures. The demands for accountability that today's university administrators must face require them to apply the sophistication of modern business and institutional management while preserving the expensive and often difficult-to-measure contributions of…

  20. Researching for Public Speaking Classes: Requiring Various Media.

    ERIC Educational Resources Information Center

    Greenberg, Cindy A.

    This paper presents steps for incorporating research into a community college public speaking class curriculum. It outlines, from an historical perspective, the different techniques and tools of research, including face-to-face contact, the printing press, modern machinery, and computers. It suggests discussing research surveys and taking students…

  1. Constructing an Affective Tutoring System for Designing Course Learning and Evaluation

    ERIC Educational Resources Information Center

    Wang, Cheng-Hung; Lin, Hao-Chiang Koong

    2018-01-01

    Computers and the Internet are indispensable in modern life. Increasingly useful digital environments and technological developments have reshaped models of knowledge acquisition. Studies on the development of online learning have yielded valuable insights. In the design of online teaching systems that can replicate face-to-face teaching,…

  2. Kassiopeia: a modern, extensible C++ particle tracking package

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Furse, Daniel; Groh, Stefan; Trost, Nikolaus

    The Kassiopeia particle tracking framework is an object-oriented software package using modern C++ techniques, written originally to meet the needs of the KATRIN collaboration. Kassiopeia features a new algorithmic paradigm for particle tracking simulations which targets experiments containing complex geometries and electromagnetic fields, with high priority put on calculation efficiency, customizability, extensibility, and ease-of-use for novice programmers. To solve Kassiopeia's target physics problem the software is capable of simulating particle trajectories governed by arbitrarily complex differential equations of motion, continuous physics processes that may in part be modeled as terms perturbing that equation of motion, stochastic processes that occur inmore » flight such as bulk scattering and decay, and stochastic surface processes occurring at interfaces, including transmission and reflection effects. This entire set of computations takes place against the backdrop of a rich geometry package which serves a variety of roles, including initialization of electromagnetic field simulations and the support of state-dependent algorithm-swapping and behavioral changes as a particle's state evolves. Thanks to the very general approach taken by Kassiopeia it can be used by other experiments facing similar challenges when calculating particle trajectories in electromagnetic fields. It is publicly available at https://github.com/KATRIN-Experiment/Kassiopeia.« less

  3. Agriculture, health, and wealth convergence: bridging traditional food systems and modern agribusiness solutions.

    PubMed

    Dubé, Laurette; Webb, Patrick; Arora, Narendra K; Pingali, Prabhu

    2014-12-01

    The causes of many vexing challenges facing 21st-century society are at the nexus of systems involved in agriculture, health and wealth production, consumption, and distribution. Using food as a test bed, and on the basis of emerging roadmaps that set achievable objectives over a 1- to 3-year horizon, we introduce this special feature with convergence thinking and practice at its core. Specifically, we discuss academic papers structured around four themes: (1) evidence for a need for convergence and underlying mechanisms at the individual and societal levels; (2) strategy for mainstreaming convergence as a driver of business engagement and innovation; (3) convergence in policy and governance; (4) convergence in metrics and methods. Academic papers under each theme are accompanied by a roadmap paper reporting on the current status of concrete transformative convergence-building projects associated with that theme. We believe that the insights provided by these papers have the potential to enable all actors throughout society to singly and collectively work to build supply and demand for nutritious food, in both traditional and modern food systems, while placing the burdens of malnutrition and ill health on their core strategic agendas. © 2014 New York Academy of Sciences.

  4. Site Sustainability Plan with FY2015 Performance Data

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nichols, Teresa A.; Lapsa, Melissa Voss; Hudey, Bryce D.

    Oak Ridge National Laboratory (ORNL) is both the largest science and energy laboratory in the US Department of Energy (DOE) complex and one of the oldest national laboratories still operating at its original site. ORNL implemented an aggressive modernization program in 2000, providing modern, energy-efficient facilities that help to support the growth of important national scientific missions while faced with the unique and challenging opportunity to integrate sustainability into legacy assets. ORNL is committed to leveraging the outcomes of DOE-sponsored research programs to maximize the efficient use of energy and natural resources across a diverse campus. ORNL leadership in conjunctionmore » with the Sustainable Campus Initiative (SCI) maintains a commitment to the integration of technical innovations into new and existing facilities, systems, and processes with a comprehensive approach to achieving DOE directives and the new Executive Order 13693. Energy efficiency, greenhouse gas reductions, climate change resiliency, and other pursuits toward integrated sustainability factor in all we do. ORNL continues to pursue and deploy innovative solutions and initiatives to advance regional, national, and worldwide sustainability and continues to transform its culture and engage employees in supporting sustainability at work, at home, and in the community.« less

  5. Role conflicts of physicians and their family members: rules but no rulebook

    PubMed Central

    Chen, Frederick M; Feudtner, Chris; Rhodes, Lorna A; Green, Larry A

    2001-01-01

    Objectives To elucidate the difficulties physicians have when a family member becomes ill and to elicit their underlying causes. Design Using a key informant technique, we solicited chairs of family medicine departments for their experiences with the health care provided to seriously ill family members. We then conducted in-depth, semistructured telephone interviews that were then transcribed, coded, and labeled for themes. Subjects 8 senior family physicians whose parents had experienced a serious illness within the past 5 years. All of the subjects reflected on experiences stemming from their fathers' illness. Results These physicians faced competing expectations: at an internal level, those of their ideal role in their family and their ideal professional identity; and at an external level, those originating from other family members and from other physicians. Reconciling these conflicting expectations was made more difficult by what they deemed to be suboptimal circumstances of the modern health care system. Conclusions Conflicting rules of appropriate conduct, compounded by the inadequacies of modern health care, make the role of physician-family member especially challenging. The medical profession needs a clearer, more trenchant understanding of this role. PMID:11577049

  6. Kassiopeia: a modern, extensible C++ particle tracking package

    DOE PAGES

    Furse, Daniel; Groh, Stefan; Trost, Nikolaus; ...

    2017-05-16

    The Kassiopeia particle tracking framework is an object-oriented software package using modern C++ techniques, written originally to meet the needs of the KATRIN collaboration. Kassiopeia features a new algorithmic paradigm for particle tracking simulations which targets experiments containing complex geometries and electromagnetic fields, with high priority put on calculation efficiency, customizability, extensibility, and ease-of-use for novice programmers. To solve Kassiopeia's target physics problem the software is capable of simulating particle trajectories governed by arbitrarily complex differential equations of motion, continuous physics processes that may in part be modeled as terms perturbing that equation of motion, stochastic processes that occur inmore » flight such as bulk scattering and decay, and stochastic surface processes occurring at interfaces, including transmission and reflection effects. This entire set of computations takes place against the backdrop of a rich geometry package which serves a variety of roles, including initialization of electromagnetic field simulations and the support of state-dependent algorithm-swapping and behavioral changes as a particle's state evolves. Thanks to the very general approach taken by Kassiopeia it can be used by other experiments facing similar challenges when calculating particle trajectories in electromagnetic fields. It is publicly available at https://github.com/KATRIN-Experiment/Kassiopeia.« less

  7. Kassiopeia: a modern, extensible C++ particle tracking package

    NASA Astrophysics Data System (ADS)

    Furse, Daniel; Groh, Stefan; Trost, Nikolaus; Babutzka, Martin; Barrett, John P.; Behrens, Jan; Buzinsky, Nicholas; Corona, Thomas; Enomoto, Sanshiro; Erhard, Moritz; Formaggio, Joseph A.; Glück, Ferenc; Harms, Fabian; Heizmann, Florian; Hilk, Daniel; Käfer, Wolfgang; Kleesiek, Marco; Leiber, Benjamin; Mertens, Susanne; Oblath, Noah S.; Renschler, Pascal; Schwarz, Johannes; Slocum, Penny L.; Wandkowsky, Nancy; Wierman, Kevin; Zacher, Michael

    2017-05-01

    The Kassiopeia particle tracking framework is an object-oriented software package using modern C++ techniques, written originally to meet the needs of the KATRIN collaboration. Kassiopeia features a new algorithmic paradigm for particle tracking simulations which targets experiments containing complex geometries and electromagnetic fields, with high priority put on calculation efficiency, customizability, extensibility, and ease-of-use for novice programmers. To solve Kassiopeia's target physics problem the software is capable of simulating particle trajectories governed by arbitrarily complex differential equations of motion, continuous physics processes that may in part be modeled as terms perturbing that equation of motion, stochastic processes that occur in flight such as bulk scattering and decay, and stochastic surface processes occurring at interfaces, including transmission and reflection effects. This entire set of computations takes place against the backdrop of a rich geometry package which serves a variety of roles, including initialization of electromagnetic field simulations and the support of state-dependent algorithm-swapping and behavioral changes as a particle’s state evolves. Thanks to the very general approach taken by Kassiopeia it can be used by other experiments facing similar challenges when calculating particle trajectories in electromagnetic fields. It is publicly available at https://github.com/KATRIN-Experiment/Kassiopeia.

  8. Challenges of Virtual School Leadership

    ERIC Educational Resources Information Center

    Richardson, Jayson W.; LaFrance, Jason; Beck, Dennis

    2015-01-01

    The purpose of this case study was to examine challenges faced by virtual school leaders in the United States. Through semistructured interviews, the researchers explored challenges faced by eighteen leaders of fully online or blended online programs. Analysis revealed six main challenges: funding, staff, accountability, time, parents, and…

  9. Challenges Faced by Female-Students in Engineering-Education

    ERIC Educational Resources Information Center

    Madara, Diana Starovoytova; Cherotich, Sharon

    2016-01-01

    Gender-related challenges in learning technical courses are universal phenomenon. These challenges could restrain female students from achieving their fullest potential. The main focus of this study, therefore, is to examine self-recognized challenges faced by undergraduate female students in pursuing engineering at the School of Engineering…

  10. The Jinn and the Computer. Consumption and Identity in Arabic Children's Magazines

    ERIC Educational Resources Information Center

    Peterson, Mark Allen

    2005-01-01

    One of the fundamental problems facing middle-class Egyptian parents is the problem of how to ensure that their children are simultaneously modern and Egyptian. Arabic children's magazines offer a window into the processes by which consumption links childhood and modernity in the social imaginations of children and their parents as they construct…

  11. The Culture Integration in The Context of National Art Schools--Prioritized Direction of Development of the Modern Humanities

    ERIC Educational Resources Information Center

    Melekhova, Ksenia Alexandrovna; Lichman, Yelena Yurievna

    2016-01-01

    The modern picture of the world is experiencing a permanent transformation, adapting to the influence of various globalization factors, the dominance of information technology, dynamic development of a material environment, etc. In these circumstances, the society faces a problem of a technocratic knowledge domination without attention to…

  12. 17 CFR 230.420 - Legibility of prospectus.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... size, type size and font, bold-face type, italics and red ink, by presenting all required information... data included therein shall be in roman type at least as large and as legible as 10-point modern type... rule 482 (17 CFR 230.482) may be in roman type at least as large and as legible as 8-point modern type...

  13. Challenges Faced by Maine School Districts in Providing High Quality Public Education. Research Brief

    ERIC Educational Resources Information Center

    Silvernail, David L.; Linet, Sarah R.

    2014-01-01

    The goal of this study was to: (1) identify challenges faced by Maine school districts in providing high quality public education; (2) describe the magnitude of the challenges; and (3) identify areas where school districts were experiencing some success in meeting these challenges. The School Districts Challenge Survey was distributed online to…

  14. The Life Review in Five Short Stories about Characters Facing Death.

    ERIC Educational Resources Information Center

    Nicholl, Grier

    1985-01-01

    Uses five modern short stories about people facing death to illustrate and connect various observations of and theories about the dying process developed by Elisabeth Kubler-Ross and Robert N. Butler. In response to the imminence of their deaths, the characters survey their past, attempting to reintegrate their life's experiences. (JAC)

  15. Predictors of Student Performance in a Blended-Learning Environment: An Empirical Investigation

    ERIC Educational Resources Information Center

    Umek, Lan; Tomaževic, Nina; Aristovnik, Aleksander; Keržic, Damijana

    2017-01-01

    Modern technologies radically simplify the availability of the latest scientific literature and offer new possibilities for sharing knowledge. Yet, most higher education institutions still rely on traditional face-to-face teaching and use e-courses "only" to supplement it. Such a combination of teaching methods is known as blended…

  16. A Guided Inquiry on Hubble Plots and the Big Bang

    NASA Astrophysics Data System (ADS)

    Forringer, Ted

    2014-04-01

    In our science for non-science majors course "21st Century Physics," we investigate modern "Hubble plots" (plots of velocity versus distance for deep space objects) in order to discuss the Big Bang, dark matter, and dark energy. There are two potential challenges that our students face when encountering these topics for the first time. The first challenge is in understanding and interpreting Hubble plots. The second is that some of our students have religious or cultural objections to the concept of a "Big Bang" or a universe that is billions of years old. This paper presents a guided inquiry exercise that was created with the goal of introducing students to Hubble plots and giving them the opportunity to discover for themselves why we believe our universe started with an explosion billions of years ago. The exercise is designed to be completed before the topics are discussed in the classroom. We did the exercise during a one hour and 45 minute "lab" time and it was done in groups of three or four students, but it would also work as an individual take-home assignment.

  17. The Enduring Challenge of Determining Pneumonia Etiology in Children: Considerations for Future Research Priorities.

    PubMed

    Feikin, Daniel R; Hammitt, Laura L; Murdoch, David R; O'Brien, Katherine L; Scott, J Anthony G

    2017-06-15

    Pneumonia kills more children each year worldwide than any other disease. Nonetheless, accurately determining the causes of childhood pneumonia has remained elusive. Over the past century, the focus of pneumonia etiology research has shifted from studies of lung aspirates and postmortem specimens intent on identifying pneumococcal disease to studies of multiple specimen types distant from the lung that are tested for multiple pathogens. Some major challenges facing modern pneumonia etiology studies include the use of nonspecific and variable case definitions, poor access to pathologic lung tissue and to specimens from fatal cases, poor diagnostic accuracy of assays (especially when testing nonpulmonary specimens), and the interpretation of results when multiple pathogens are detected in a given individual. The future of childhood pneumonia etiology research will likely require integrating data from complementary approaches, including applications of advanced molecular diagnostics and vaccine probe studies, as well as a renewed emphasis on lung aspirates from radiologically confirmed pneumonia and postmortem examinations. © The Author 2017. Published by Oxford University Press for the Infectious Diseases Society of America.

  18. Balanced diets in food systems: emerging trends and challenges for human health.

    PubMed

    Sammugam, Lakhsmi; Pasupuleti, Visweswara Rao

    2018-04-25

    Processed foods, generally known as modified raw foods produced by innovative processing technologies alters the food constituents such natural enzymes, fatty acids, micronutrients, macronutrients and vitamins. In contrast to fresh and unprocessed foods, processed foods are guaranteed to be safer, imperishable, long lasting and consist high level of nutrients bioactivity. Currently, the evolution in food processing technologies is necessary to face food security and safety, nutrition demand, its availability and also other global challenges in the food system. In this scenario, this review consists of information on two food processing technologies, which effects on processed foods before and after processing and the impact of food products on human health. It is also very well established that understanding the type and structure of foods to be processed can assist food processing industries towards advancement of novel food products. In connection with this fact, the present article also discusses the emerging trends and possible modifications in food processing technologies with the combination of conventional and modern techniques to get the suitable nutritional and safety qualities in food.

  19. Standards for Radiation Effects Testing: Ensuring Scientific Rigor in the Face of Budget Realities and Modern Device Challenges

    NASA Technical Reports Server (NTRS)

    Lauenstein, J M.

    2015-01-01

    An overview is presented of the space radiation environment and its effects on electrical, electronic, and electromechanical parts. Relevant test standards and guidelines are listed. Test standards and guidelines are necessary to ensure best practices, minimize and bound systematic and random errors, and to ensure comparable results from different testers and vendors. Test standards are by their nature static but exist in a dynamic environment of advancing technology and radiation effects research. New technologies, failure mechanisms, and advancement in our understanding of known failure mechanisms drive the revision or development of test standards. Changes to standards must be weighed against their impact on cost and existing part qualifications. There must be consensus on new best practices. The complexity of some new technologies exceeds the scope of existing test standards and may require development of a guideline specific to the technology. Examples are given to illuminate the value and limitations of key radiation test standards as well as the challenges in keeping these standards up to date.

  20. Strategic planning in diagnostic imaging: meeting the challenge.

    PubMed

    Lexa, Frank J

    2008-02-01

    The 21st century has raised new and significant challenges to the practice of diagnostic imaging. Radiologists will have to navigate a difficult path as they face threats from disruptive technologies, adverse demographic changes, pressures to limit reimbursement both from the public and from the private sectors, increased domestic and crossborder competition, and many others. Success in these trying times will require greater attention to strategic planning if we are to thrive and survive in radiology. Strategic planning and tactical implementation methodologies were reviewed, from Sun Tzu to the present day, for applicability to the needs of modern radiology groups. A framework for developing and implementing strategic plans was constructed to assist radiology leaders and groups in considering the spectrum of tasks, from gathering intelligence, to developing scenarios, to implementing and evaluating tactical plans. Strategy and tactics are too important to be ignored or left to others. They need to be core activities for all radiology leaders. Frameworks can be used to help in providing structure and rigour to strategic planning efforts at the department and group level.

  1. The challenge of cardiac modeling--interaction and integration.

    PubMed

    Sideman, Samuel

    2006-10-01

    The goal of clinical cardiology is to obtain an integrated picture of the interacting parameters of muscle and vessel mechanics, blood circulation and myocardial perfusion, oxygen consumption and energy metabolism, and electrical activation and heart rate, thus relating to the true physiological and pathophysiological characteristics of the heart. Scientific insight into the cardiac physiology and performance is achieved by utilizing life sciences, for example, molecular biology, genetics and related intra- and intercellular phenomena, as well as the exact sciences, for example, mathematics, computer science, and related imaging and visualization techniques. The tools to achieve these goals are based on the intimate interactions between engineering science and medicine and the developments of modern, medically oriented technology. Most significant is the beneficiary effect of the globalization of science, the Internet, and the unprecedented international interaction and scientific cooperation in facing difficult multidisciplined challenges. This meeting aims to explore some important interactions in the cardiac system and relate to the integration of spatial and temporal interacting system parameters, so as to gain better insight into the structure and function of the cardiac system, thus leading to better therapeutic modalities.

  2. Delayed fertility transition among indigenous women in the Ecuadorian Amazon.

    PubMed

    Davis, Jason; Bilsborrow, Richard; Gray, Clark

    2015-03-01

    Communities indigenous to the Amazon are among the few remaining worldwide still practicing near-natural fertility, without the use of modern contraceptives. Given the large proportion of women desiring no more births, information on the challenges women there face in limiting fertility would be useful. Samples of women of reproductive age from five indigenous ethnic groups in the Northern Ecuadorian Amazon were surveyed in 2001 and 2012. Cross-sectional and longitudinal analyses examined married women's desire for another child at both times and modern contraceptive use in 2012, as well as determinants of a change in women's desire to have more children and of the number of children born during the study period. In 2001, 48% of married women desired another child, 2% used a modern contraceptive and 50% had an unmet need for limiting; in 2012, the proportions were 40%, 19% and 47%, respectively. The total fertility rate was 7.9 births per woman in 2001 and 7.0 births per woman in 2012. Characteristics associated with wanting another child in 2001 and 2012 included parity (odds ratios, 0.6 and 0.4, respectively) and experience of a child death (2.0 each); characteristics associated with contraceptive use in 2012 included desire for another child, experience of a child death and presence of a community health worker (0.3-0.5). Number of children born was positively associated, and the square of the term negatively associated, with no longer wanting more children in 2012 among women who wanted more in 2001 (2.1 and 0.9, respectively). Indigenous women in the Northern Ecuadorian Amazon appear to be making the transition to lower fertility. Insufficient access to credible information about the safety and efficacy of modern contraceptives, however, may slow the transition.

  3. The 'special obligations' of the modern Hippocratic Oath for 21st century medicine.

    PubMed

    Holmboe, Eric; Bernabeo, Elizabeth

    2014-01-01

    Profound advances and discoveries in medicine have markedly improved the lives of many over the 50 years since the modern Hippocratic Oath was written. Regrettably, these advances were and continue to be implemented suboptimally and inequitably across the globe. 'Special obligations to all my fellow humans' is an important theme of the modern Oath. From this perspective, we reflect on the special obligations of the medical profession, and examine how these obligations have changed over the past 50 years. We draw from perspectives of the social contract, professionalism, quality improvement, patient safety and a group of 31 international colleagues involved in medical education as we examine these obligations for individual doctors, health care institutions and medical education systems. The perspectives of the 31 clinician-educators helped us to situate the meaning of the theme of 'special obligations' in the context of challenges facing medical education and health care in the 21st century. Improving the quality of care and patient safety, and reducing health care disparities are now paramount as 'special obligations' for doctors, health care systems and medical education organisations, and require us to work collectively and collaboratively in an increasingly interconnected world. In our view, traditions such as the Hippocratic Oath will be worthy of public support only when the medical profession demonstrates in meaningful and transparent ways that it is meeting its social and civic obligations to make the world, not just health care, a better place. © 2013 John Wiley & Sons Ltd.

  4. A study of the information seeking behaviour of hospital pharmacists: empirical evidence from Greece.

    PubMed

    Kostagiolas, Petros A; Aggelopoulou, Vasiliki A; Niakas, Dimitris

    2011-12-01

    Hospital pharmacists need access to high-quality information in order to constantly update their knowledge and improve their skills. In their modern role, they are expected to address three types of challenges: scientific, organizational and administrative, thus having an increased need for adequate information and library services. This study investigates the information-seeking behaviour of public hospital pharmacists providing evidence from Greece that could be used to encourage the development of effective information hospital services and study the links between the information seeking behaviour of hospital pharmacists and their modern scientific and professional role. An empirical research was conducted between January and February 2010 with the development and distribution of a structured questionnaire. The questionnaire was filled in and returned by 88 public hospital pharmacists from a total of 286 working in all Greek public hospitals, providing a response rate of 31%. The hospital pharmacists in Greece are in search of scientific information and, more particularly, pharmaceutical information (e.g., drug indications, storage, dosage and prices). The Internet and the National Organization of Medicines are their main information sources, while the lack of time and organized information are the main obstacles they have to face when seeking information. The modern professional role of hospital pharmacists as invaluable contributors to efficient and safer healthcare services may be further supported through the development of specialized libraries and information services within Greek public hospitals. © 2011 The authors. Health Information and Libraries Journal © 2011 Health Libraries Group.

  5. What Factors Contribute to Intimate Partner Violence Against Women in Urban, Conflict-Affected Settings? Qualitative Findings from Abidjan, Côte d'Ivoire.

    PubMed

    Cardoso, L F; Gupta, J; Shuman, S; Cole, H; Kpebo, D; Falb, K L

    2016-04-01

    Rapid urbanization is a key driver of the unique set of health risks facing urban populations. One of the most critical health hazards facing urban women is intimate partner violence (IPV). In post-conflict urban areas, women may face an even greater risk of IPV. Yet, few studies have examined the IPV experiences of urban-dwelling, conflict-affected women, including those who have been internally displaced. This study qualitatively examined the social and structural characteristics of the urban environment that contributed to the IPV experiences of women residing in post-conflict Abidjan, Côte d'Ivoire. Ten focus groups were conducted with men and women, both internally displaced (IDPs) and non-displaced. Lack of support networks, changing gender roles, and tensions between traditional gender norms and those of the "modern" city were reported as key contributors to IPV. Urban poverty and with it unemployment, food insecurity, and housing instability also played a role. Finally, IDPs faced heightened vulnerability to IPV as a result of displacement and discrimination. The relationship between economic strains and IPV are similar to other conflict-affected settings, but Abidjan's urban environment presented other unique characteristics contributing to IPV. Understanding these factors is crucial to designing appropriate services for women and for implementing IPV reduction interventions in urban areas. Strengthening formal and informal mechanisms for help-seeking, utilizing multi-modal interventions that address economic stress and challenge inequitable gender norms, as well as tailoring programs specifically for IDPs, are some considerations for IPV program planning focused on conflict-affected women in urban areas.

  6. TMR tape drive for a 15 TB cartridge

    NASA Astrophysics Data System (ADS)

    Biskeborn, Robert G.; Fontana, Robert E.; Lo, Calvin S.; Czarnecki, W. Stanley; Liang, Jason; Iben, Icko E. T.; Decad, Gary M.; Hipolito, Venus A.

    2018-05-01

    This paper highlights the development of tunnel magnetoresistive (TMR) sensors for magnetic tape recording applications. This has led to the introduction of a tape drives supporting a 15 TB native tape cartridge, currently the highest capacity available. Underscoring this development is the fact that the TMR sensors must run in continual contact with the tape media. This is contrasted with modern hard disk drive (hdd) sensors, which fly above the disk platters. Various challenges encountered in developing and deploying TMR are presented. In addition, advances to the write transducer are also discussed. Lastly, the authors show that future density scaling for tape recording, unlike that for hdd, is not facing limits imposed by photolithography or superparamagnetic physics, suggesting that cartridge capacity improvements of 4 to 6x will be achieved in the next 4 to 8 years.

  7. The teaching of medical ethics to medical students.

    PubMed Central

    Glick, S M

    1994-01-01

    Teaching medical ethics to medical students in a pluralistic society is a challenging task. Teachers of ethics have obligations not just to teach the subject matter but to help create an academic environment in which well motivated students have reinforcement of their inherent good qualities. Emphasis should be placed on the ethical aspects of daily medical practice and not just on the dramatic dilemmas raised by modern technology. Interdisciplinary teaching should be encouraged and teaching should span the entire duration of medical studies. Attention should be paid particularly to ethical problems faced by the students themselves, preferably at the time when the problems are most on the students' minds. A high level of academic demands, including critical examination of students' progress is recommended. Finally, personal humility on the part of teachers can help set a good example for students to follow. PMID:7861430

  8. Rapid Bacterial Detection via an All-Electronic CMOS Biosensor

    PubMed Central

    Nikkhoo, Nasim; Cumby, Nichole; Gulak, P. Glenn; Maxwell, Karen L.

    2016-01-01

    The timely and accurate diagnosis of infectious diseases is one of the greatest challenges currently facing modern medicine. The development of innovative techniques for the rapid and accurate identification of bacterial pathogens in point-of-care facilities using low-cost, portable instruments is essential. We have developed a novel all-electronic biosensor that is able to identify bacteria in less than ten minutes. This technology exploits bacteriocins, protein toxins naturally produced by bacteria, as the selective biological detection element. The bacteriocins are integrated with an array of potassium-selective sensors in Complementary Metal Oxide Semiconductor technology to provide an inexpensive bacterial biosensor. An electronic platform connects the CMOS sensor to a computer for processing and real-time visualization. We have used this technology to successfully identify both Gram-positive and Gram-negative bacteria commonly found in human infections. PMID:27618185

  9. Challenges Facing Teachers New to Working in Schools Overseas

    ERIC Educational Resources Information Center

    Halicioglu, Margaret L.

    2015-01-01

    This article considers the potential challenges facing teachers moving abroad for the first time, both professional challenges in their school and personal challenges in their private life. It suggests that such teachers embarking on a professional adventure overseas would benefit from careful consideration of the kind of school they will thrive…

  10. An Exploration of Challenges Facing Division III Athletic Directors

    ERIC Educational Resources Information Center

    Engbers, Jeffrey L.

    2011-01-01

    The purpose of this study was to establish a basic understanding of the challenges associated with directing athletic programs at NCAA Division III Institutions. Specifically, this study identified the frequency, intensity, and time allocated to common challenges facing the position of the NCAA Division III AD. The challenges were examined using…

  11. The Challenges Facing School Governing Bodies in England: A "Perfect Storm"?

    ERIC Educational Resources Information Center

    James, Chris; Brammer, Steve; Connolly, Michael; Spicer, David Eddy; James, Jane; Jones, Jeff

    2013-01-01

    The governing bodies of publicly funded schools in England are currently facing a number of substantive challenges of various kinds. Many of the challenges are long-standing, while others relate to the current context for governing wrought by recent education policy developments initiated by central government. A number of the challenges are…

  12. Regulation of ion homeostasis in plants: current approaches and future challenges.

    PubMed

    Rouached, Hatem; Secco, David; Arpat, Bulak A

    2010-05-01

    The dependency of plants on essential macro- and micro-elements to complete their life cycle serves as a major entry point of these elements into the global food web. However, plants often face depletion of one or more essential elements limiting their growth. Thus, in modern agriculture, improving plant mineral nutrition has gained fundamental importance in order to address the issue of sustainable food resources for the growing world population. Heavy fertilization of soil was, for long time, chosen as a strategy to cope with the deficiency of these elements. Yet, this strategy is neither economically nor ecologically conceivable at long-term. As an alternative, genetic and breeding approaches that provide plants new characteristics enabling them to grow in nutrient-depleted soils, has become a major focal interest. The research emphasis so far has been on elucidating the molecular physiology of individual nutritive elements. However, in practice, application of such knowledge is hindered by complex cross-talks, which are emerging in the face of new data, between these elements. Developing integrative approaches, combining genetic, comparative genomics and 'omics' platforms, is crucial to untangle the interconnected signaling networks regulating ion homeostasis in plants.

  13. Richard Dadd: the patient, the artist, and the "face of madness".

    PubMed

    Huddleston, Samuel; Russell, G A

    2015-01-01

    Richard Dadd (1817-1886) was a well-known Victorian artist who murdered his father, compelled by the delusion that a demonic force possessed his father's body. He was one of the first to bypass execution by reason of insanity and spent the remainder of his life in the Bethlem and Broadmoor asylums. Dadd is rare both as a patient and an artist because he left behind nearly a 40-year record of artwork and journals, which constitute a unique medical and psychiatric resource at a time when the ideas on the relationship of facial expression and madness were changing. Sir Charles Bell's (1774-1842) widely accepted views that the "face of madness" is bestial and anatomically distinctive were being challenged by such physicians as Sir Alexander Morison (1779-1866), who was also Dadd's own "alienist" (i.e., psychiatrist). The purpose of this article is to explore the nature and extent of the influence of Bell and Morison on Dadd, which has not been brought out in the existing studies. By a comparative analysis, it will be shown that Dadd may have conveyed a different view in his works that foreshadows subsequent developments that are closer to a modern understanding.

  14. Modernizing "San Antonio Independent School District v. Rodriguez": How Evolving Supreme Court Jurisprudence Changes the Face of Education Finance Litigation

    ERIC Educational Resources Information Center

    Saleh, Matthew

    2011-01-01

    This article aims to "modernize" the current legal debate over inequitable public school funding at the state and local level. The 1973 Supreme Court case of "San Antonio Independent School District v. Rodriguez" established precedent, allowing for property-tax based education funding programs at the state-level--a major source…

  15. Leadership and the emergency department.

    PubMed

    LaSalle, Gar

    2004-02-01

    Emergency medicine, as the nation's health care system's safety net, is facing ever increasing demands on its resources and infrastructure. Classic and modern theories of leadership, which include broader based models that in corporate team responsibilities, should be studied by anyone wearing the mantle of leadership in emergency medicine, and the Realpolitik of the modern hospital must be accommodated if leadership efforts are to succeed.

  16. Face-space: A unifying concept in face recognition research.

    PubMed

    Valentine, Tim; Lewis, Michael B; Hills, Peter J

    2016-10-01

    The concept of a multidimensional psychological space, in which faces can be represented according to their perceived properties, is fundamental to the modern theorist in face processing. Yet the idea was not clearly expressed until 1991. The background that led to the development of face-space is explained, and its continuing influence on theories of face processing is discussed. Research that has explored the properties of the face-space and sought to understand caricature, including facial adaptation paradigms, is reviewed. Face-space as a theoretical framework for understanding the effect of ethnicity and the development of face recognition is evaluated. Finally, two applications of face-space in the forensic setting are discussed. From initially being presented as a model to explain distinctiveness, inversion, and the effect of ethnicity, face-space has become a central pillar in many aspects of face processing. It is currently being developed to help us understand adaptation effects with faces. While being in principle a simple concept, face-space has shaped, and continues to shape, our understanding of face perception.

  17. An Interdisciplinary Evaluation of Transactive Memory in Distributed Cyber Teams

    ERIC Educational Resources Information Center

    Mancuso, Vincent Francis

    2012-01-01

    In the modern workplace, collaboration is no longer only a face-to-face process. When working together, it is common for teams to rely on technology and operate across geographic, temporal and cultural boundaries. Most research, when looking at distributed teams, takes a uni-disciplinary perspective and fails to address the entire problem space.…

  18. How Long Has This Been Going On? "Harpers Bazaar,""Funny Face," and the Construction of the Modernist Woman.

    ERIC Educational Resources Information Center

    Sellers, Susan

    1995-01-01

    Uses the Hollywood musical "Funny Face" as a departure for rethinking the incorporation of modern European design in the context of postwar American consumer culture. Discusses ways women understood the fashion magazine and, consequently, modernists form language, as a purveyor of fantasy, cultural capital, and a restrictive,…

  19. [Nursing stance in the face of Jinn possession in Mayotte].

    PubMed

    Gillard-Berthod, Claire

    2013-01-01

    Caregivers and nursing students practising in Mayotte can find themselves in a difficult position when faced with patients believing themselves to be possessed by spirits called Jinn. Through a multidisciplinary roundtable, different perspectives and practices can be shared leading to a more enlightened treatment of patients which respects their beliefs, blending traditional and modern medicine.

  20. English in Class and on the Go: Multimodal U-Learning

    ERIC Educational Resources Information Center

    García-Sánchez, Soraya

    2012-01-01

    This article aims to analyse different ubiquitous learning (u-Learning) platforms used when learning English as a Foreign Language (EFL) as part of the Modern Languages Degree at the Universidad de Las Palmas de Gran Canaria (ULPGC). The combination of face-to-face lessons with multimedia content and digital mediated learning allows today's native…

  1. An Empirical Evaluation of Critical Factors Influencing Learner Satisfaction in Blended Learning: A Pilot Study

    ERIC Educational Resources Information Center

    Chen, Won Sun; Yao, Adrian Yong Tat

    2016-01-01

    Blended learning, a convergence of e-learning approach and face-to-face learning, has been regarded as a new paradigm in modern education. The degree of learners' satisfaction with blended learning played a crucial role in evaluating the effectiveness of blended learning adoption. Therefore, this study examined the primary factors affecting…

  2. Research and Discovery Science and the Future of Dental Education and Practice.

    PubMed

    Polverini, Peter J; Krebsbach, Paul H

    2017-09-01

    Dental graduates of 2040 will face new and complex challenges. If they are to meet these challenges, dental schools must develop a research and discovery mission that will equip graduates with the new knowledge required to function in a modern health care environment. The dental practitioner of 2040 will place greater emphasis on risk assessment, disease prevention, and health maintenance; and the emerging discipline of precision medicine and systems biology will revolutionize disease diagnosis and reveal new targeted therapies. The dental graduate of 2040 will be expected to function effectively in a collaborative, learning health care system and to understand the impact of health care policy on local, national, and global communities. Emerging scientific fields such as big data analytics, stem cell biology, tissue engineering, and advanced biomimetics will impact dental practice. Despite all the warning signs indicating how the changing scientific and heath care landscape will dramatically alter dental education and dental practice, dental schools have yet to reconsider their research and educational priorities and clinical practice objectives. Until dental schools and the practicing community come to grips with these challenges, this persistent attitude of complacency will likely be at the dental profession's peril. This article was written as part of the project "Advancing Dental Education in the 21 st Century."

  3. The Borderlands and climate change: Chapter 10 in United States-Mexican Borderlands: Facing tomorrow's challenges through USGS science

    USGS Publications Warehouse

    Fitzpatrick, Joan; Gray, Floyd; Dubiel, Russell; Langman, Jeff; Moring, J. Bruce; Norman, Laura M.; Page, William R.; Parcher, Jean W.

    2013-01-01

    The prediction of global climate change in response to both natural forces and human activity is one of the defining issues of our times. The unprecedented observational capacity of modern earth-orbiting satellites coupled with the development of robust computational representations (models) of the Earth’s weather and climate systems afford us the opportunity to observe and investigate how these systems work now, how they have worked in the past, and how they will work in the future when forced in specific ways. In the most recent report on global climate change by the Intergovernmental Panel on Climate Change (IPCC; Solomon and others, 2007), analyses using multiple climate models support recent observations that the Earth’s climate is changing in response to a combination of natural and human-induced causes. These changes will be significant in the United States–Mexican border region, where the process of climate change affects all of the Borderlands challenge themes discussed in the preceding chapters. The dual possibilities of both significantly-changed climate and increasing variability in climate make it challenging to take full measure of the potential effects because the Borderlands already experience a high degree of interannual variability and climatological extremes.

  4. Challenges of teacher-based clinical evaluation from nursing students' point of view: Qualitative content analysis.

    PubMed

    Sadeghi, Tabandeh; Seyed Bagheri, Seyed Hamid

    2017-01-01

    Clinical evaluation is very important in the educational system of nursing. One of the most common methods of clinical evaluation is evaluation by the teacher, but the challenges that students would face in this evaluation method, have not been mentioned. Thus, this study aimed to explore the experiences and views of nursing students about the challenges of teacher-based clinical evaluation. This study was a descriptive qualitative study with a qualitative content analysis approach. Data were gathered through semi-structured focused group sessions with undergraduate nursing students who were passing their 8 th semester at Rafsanjan University of Medical Sciences. Date were analyzed using Graneheim and Lundman's proposed method. Data collection and analysis were concurrent. According to the findings, "factitious evaluation" was the main theme of study that consisted of three categories: "Personal preferences," "unfairness" and "shirking responsibility." These categories are explained using quotes derived from the data. According to the results of this study, teacher-based clinical evaluation would lead to factitious evaluation. Thus, changing this approach of evaluation toward modern methods of evaluation is suggested. The finding can help nursing instructors to get a better understanding of the nursing students' point of view toward this evaluation approach and as a result could be planning for changing of this approach.

  5. On-chip single photon filtering and multiplexing in hybrid quantum photonic circuits.

    PubMed

    Elshaari, Ali W; Zadeh, Iman Esmaeil; Fognini, Andreas; Reimer, Michael E; Dalacu, Dan; Poole, Philip J; Zwiller, Val; Jöns, Klaus D

    2017-08-30

    Quantum light plays a pivotal role in modern science and future photonic applications. Since the advent of integrated quantum nanophotonics different material platforms based on III-V nanostructures-, colour centers-, and nonlinear waveguides as on-chip light sources have been investigated. Each platform has unique advantages and limitations; however, all implementations face major challenges with filtering of individual quantum states, scalable integration, deterministic multiplexing of selected quantum emitters, and on-chip excitation suppression. Here we overcome all of these challenges with a hybrid and scalable approach, where single III-V quantum emitters are positioned and deterministically integrated in a complementary metal-oxide-semiconductor-compatible photonic circuit. We demonstrate reconfigurable on-chip single-photon filtering and wavelength division multiplexing with a foot print one million times smaller than similar table-top approaches, while offering excitation suppression of more than 95 dB and efficient routing of single photons over a bandwidth of 40 nm. Our work marks an important step to harvest quantum optical technologies' full potential.Combining different integration platforms on the same chip is currently one of the main challenges for quantum technologies. Here, Elshaari et al. show III-V Quantum Dots embedded in nanowires operating in a CMOS compatible circuit, with controlled on-chip filtering and tunable routing.

  6. Integrated, Multidisciplinary and Technology-Enhanced Science Education: The Next Frontier

    PubMed Central

    Dinov, Ivo D.

    2011-01-01

    Contemporary science education at all levels presents several critical pedagogical and social challenges to educators and learners alike. Among these challenges are the widening Intergenerational Information Technology (IIT) divide and the need for a comprehensive and balanced multidisciplinary training. In the past few years, it has become clear that one significant hurdle impedes the efforts to integrate information technology in the classroom – the Intergenerational IT divide. The IIT gap reflects a different growing misalignment between providers and recipients of the science and technology educational content in terms of the expected vs. supplied, needed vs. perceived and contextual vs. abstract specialized learning. The common K-12 teacher or college instructor is much less familiar with, and slower to adapt to, the new ether of communication and novel IT resources. The transfer and blending of data, research challenges and methodologies between diverse areas of science is also critical in motivating wider spectra of students, demonstrating cross-disciplinary methodological concepts and synergies, as well as for engaging students in research projects. This article discusses the problems faced by modern science educators and suggests some methods and vision for coping with the increasing IIT divide and the social need to train “complete” and broadly educated citizens. PMID:21552453

  7. Challenges of International Students in a Japanese University: Ethnographic Perspectives

    ERIC Educational Resources Information Center

    Lee, Ju Seong

    2017-01-01

    The author investigates what challenges four international students (Vietnamese, Filipino, Brazilian, and Chinese) faced and how they coped with these dilemmas in a Japanese language program during the first semester in 2014. Multiple apparatuses (e.g., field notes, face-to-face oral interviews, focal group conversations, and semi-structured…

  8. Muslims in America: Identity, Diversity and the Challenge of Understanding. 2001 Carnegie Challenge.

    ERIC Educational Resources Information Center

    Afridi, Sam

    This paper discusses challenges and opportunities facing Muslims in the United States, where between 5 to 8 million Muslims live (the fastest growing religion in the country). American Muslims face many challenges, and the public has little understanding of the teachings and practice of Islam. Muslims are prone to negative stereotypes, ethnic…

  9. 'Everyone has a secret they keep close to their hearts': challenges faced by adolescents living with HIV infection at the Kenyan coast.

    PubMed

    Abubakar, Amina; Van de Vijver, Fons J R; Fischer, Ronald; Hassan, Amin S; K Gona, Joseph; Dzombo, Judith Tumaini; Bomu, Grace; Katana, Khamis; Newton, Charles R

    2016-02-29

    The upsurge in the uptake of antiretroviral therapy (ART) has led to a significant increase in the survival of vertically acquired HIV infected children, many of whom are currently living into adolescence and early adulthood. However little if anything is known of the lived experiences and the challenges faced by HIV positive adolescents in the African context. We set out to investigate psychosocial challenges faced by HIV infected adolescents on the Kenyan coast. A total of 44 participants (12 HIV-infected adolescents, 7 HIV uninfected adolescents, and 25 key informants) took part in this qualitative study, using individually administered in-depth interviews. A framework approach was used to analyze the data using NVIVO software. We observed that the challenges faced by adolescents in rural Kenya could be placed into six major themes: poverty, poor mental and physical health, the lack of a school system that is responsive to their needs, challenges in how to disclose to peers and family members, high levels of stigma in its various forms, and challenges of medical adherence leading to the need for close monitoring. In this African community, vertically acquired HIV-infected adolescents face a complex set of social, economic and medical challenges. Our study points to the urgent need to develop multisectorial intervention support programmes to fully address these challenges.

  10. Army Communicator. Volume 32, Number 3, Summer 2007

    DTIC Science & Technology

    2007-01-01

    goal of bringing people from across the Army together to talk about the issues and challenges they are experiencing in the field and try to work out...actually facing the challenges . Each work- shop had a mediator who collected information on issues being faced and suggested solutions to these problems...these possible items that Signal Center actions may be put forth to bring about resolutions to the challenges facing the warfighter in the field. “I

  11. Indicators of young women's modern contraceptive use in Burkina Faso and Mali from Demographic and Health Survey data.

    PubMed

    O'Regan, Amy; Thompson, Gretchen

    2017-01-01

    High total fertility rates in Burkina Faso and Mali are leading to population growth beyond the agricultural and fiscal means of its citizens. Providing access to affordable family planning methods is a key step in driving the demographic transition where fertility and mortality rates decline. Furthermore, both nations face significant challenges as climate change is projected to disproportionately impact the western Sahel region undermining environmental, social and economic stability within the region. This analysis was included in formative research to inform family planning programming. The aim of this study was to examine possible indicators of long acting and permanent contraceptive method (LAPM) and short-term method (STM) use for young women in Burkina Faso and Mali. Secondary data analysis was conducted using the three most recent Demographic and Health Survey (DHS) datasets for Burkina Faso (1998, 2003, 2010) and Mali (2001, 2006, 2012). Women ages 15-24, at risk for unwanted pregnancy were included in these analyses. Summary descriptive statistics across all time points are reported and multinomial logistic regression was used with the most recent data to determine potential indicators of different types of modern contraceptive methods. In Burkina Faso in 2010, 24% of women ages 15-24 were using modern contraceptives. Only 2.9% reported using LAPMs in 2010, an increase from 0.3% in 1998. In Mali, modern contraceptive use increased more recently, rising from 9.4% in 2001 to 10.2% in 2006 to 15.3% in 2012. LAPM use also increased from 0.3% in 2001 to 4.1% in 2012. Significant indicators of LAPM contraceptive use in both countries included educational attainment, ideal family size, home ownership and husband's desire for more children. Young women in Burkina Faso and Mali are increasingly using modern contraceptives for family planning; however, the LAPM contraceptive prevalence rate remains low. Our analysis indicates that social norms around ideal family size for both men and women continue to drive young women's choices around family planning and impede use of LAPMs. To increase modern contraceptive use and curb fertility rates, local governments and development organizations should focus on women's empowerment and include male partners.

  12. Exploring the challenges faced by polytechnic students

    NASA Astrophysics Data System (ADS)

    Matore, Mohd Effendi @ Ewan Mohd; Khairani, Ahmad Zamri

    2015-02-01

    This study aims to identify other challenges besides those already faced by students, in seven polytechnics in Malaysia as a continuation to the previous research that had identified 52 main challenges faced by students using the Rasch Model. The explorative study focuses on the challenges that are not included in the Mooney Problem Checklist (MPCL). A total of 121 polytechnic students submitted 183 written responses through the open questions provided. Two hundred fifty two students had responded from a students' perspective on the dichotomous questions regarding their view on the challenges faced. The data was analysed qualitatively using the NVivo 8.0. The findings showed that students from Politeknik Seberang Perai (PSP) gave the highest response, which was 56 (30.6%) and Politeknik Metro Kuala Lumpur (PMKL) had the lowest response of 2 (1.09%). Five dominant challenges were identified, which were the English language (32, 17.5%), learning (14, 7.7%), vehicles (13, 7.1%), information technology and communication (ICT) (13, 7.1%), and peers (11, 6.0%). This article, however, focus on three apparent challenges, namely, English language, vehicles, as well as computer and ICT, as the challenges of learning and peers had been analysed in the previous MPCL. The challenge of English language that had been raised was regarding the weakness in commanding the aspects of speech and fluency. The computer and ICT challenge covered the weakness in mastering ICT and computers, as well as computer breakdowns and low-performance computers. The challenge of vehicles emphasized the unavailability of vehicles to attend lectures and go elsewhere, lack of transportation service in the polytechnic and not having a valid driving license. These challenges are very relevant and need to be discussed in an effort to prepare polytechnics in facing the transformational process of polytechnics.

  13. Neural synchronization during face-to-face communication.

    PubMed

    Jiang, Jing; Dai, Bohan; Peng, Danling; Zhu, Chaozhe; Liu, Li; Lu, Chunming

    2012-11-07

    Although the human brain may have evolutionarily adapted to face-to-face communication, other modes of communication, e.g., telephone and e-mail, increasingly dominate our modern daily life. This study examined the neural difference between face-to-face communication and other types of communication by simultaneously measuring two brains using a hyperscanning approach. The results showed a significant increase in the neural synchronization in the left inferior frontal cortex during a face-to-face dialog between partners but none during a back-to-back dialog, a face-to-face monologue, or a back-to-back monologue. Moreover, the neural synchronization between partners during the face-to-face dialog resulted primarily from the direct interactions between the partners, including multimodal sensory information integration and turn-taking behavior. The communicating behavior during the face-to-face dialog could be predicted accurately based on the neural synchronization level. These results suggest that face-to-face communication, particularly dialog, has special neural features that other types of communication do not have and that the neural synchronization between partners may underlie successful face-to-face communication.

  14. Challenges and Changes Faced by Rural Superintendents

    ERIC Educational Resources Information Center

    Lamkin, Marcia L.

    2006-01-01

    This research study was designed to build grounded theory about the challenges faced by rural superintendents. Participating rural superintendents identified five areas that presented a challenge but that also applied to superintendents in other settings: school law, finance, personnel, government mandates, and district or board policies. Further,…

  15. Finding a Trans-Affirmative Provider: Challenges Faced by Trans and Gender Diverse Psychologists and Psychology Trainees.

    PubMed

    Dickey, Lore M; Singh, Anneliese A

    2017-08-01

    This article explores some of the challenges faced by trans and gender diverse (TGD) individuals who not only are attempting to access trans-affirmative care, but who are also members of the very profession from which they are seeking services. The authors explore challenges related to finding supervision, accessing care for assessment services, and finding a provider for personal counseling. With each example, the authors unpack the challenges and also address the implications for training for all involved. Based on these challenges that TGD psychologists and trainees face in attempting to access care, the authors provide recommendations related to trans-affirmative training for psychologists. © 2017 Wiley Periodicals, Inc.

  16. The Invisible Army

    PubMed Central

    2017-01-01

    ABSTRACT The “invisible army” of clinical microbiologists is facing major changes and challenges. The rate of change in both the science and technology is accelerating with no end in sight, putting pressure on our army to learn and adapt as never before. Health care funding in the United States is undergoing dramatic change which will require a new set of assumptions about how clinical microbiology is practiced here. A major challenge facing the discipline is the replacement of a generation of clinical microbiologists. In my opinion, it is incumbent on us in the invisible army to continue to work with the American Society for Microbiology (ASM) in meeting the future challenges faced by our discipline. In this commentary, I will first discuss some recent history of clinical microbiology within ASM and then some current challenges we face. PMID:28659316

  17. Children at Risk: Global Views on Challenges Facing Children

    ERIC Educational Resources Information Center

    Neugebauer, Roger

    2011-01-01

    Members of the World Forum community were invited to respond to the question: "What is the most urgent challenge facing young children in your country?" Here are some of their responses. Jamils Richard Achunji Anguaseh mentions that in Cameroon, young children face lots of insecurity, both from health hazards and poor parenting practices. There…

  18. Forest in My Neighborhood: An Exercise Using Aerial Photos to Engage Students in Forest Ecology & Land Use History

    ERIC Educational Resources Information Center

    Matlack, Glenn R.; McEwan, Ryan W.

    2008-01-01

    Human activity has profoundly altered the deciduous forest of the eastern United States. Modern forest is a patchwork of stands of varying ages, sizes, and shapes reflecting a complex history of land use. Much modern forest is nestled in and around human communities, and faces the threat of imminent clearance for residential and commercial…

  19. Taming the Data Deluge to Unravel the Mysteries of the Universe

    NASA Astrophysics Data System (ADS)

    Johnston-Hollitt, M.

    2017-04-01

    Modern Astrophysics is one of the most data intensive research fields in the world and is driving many of the required innovations in the "big data" space. Foremost in astronomy in terms of data generation is radio astronomy, and in the last decade an increase in global interest and investment in the field had led to a large number of new or upgraded facilities which are each currently generating petabytes of data per annum. The peak of this so-called 'radio renaissance' will be the Square Kilometre Array (SKA) - a global observatory designed to uncover the mysteries of the Universe. The SKA will create the highest resolution, fastest frame rate movie of the evolving Universe ever and in doing so will generate 160 terrabytes of data a second, or close to 5 zettabytes of data per annum. Furthermore, due to the extreme faintness of extraterrestrial radio signals, the telescope elements for the SKA must be located in radio quite parts of the world with very low population density. Thus the project aims to build the most data intensive scientific experiment ever, in some of the most remote places on Earth. Generating and serving scientific data products of this scale to a global community of researchers from remote locations is just the first of the "big data" challenges the project faces. Coordination of a global network of tiered data resources will be required along with software tools to exploit the vast sea of results generated. In fact, to fully realize the enormous scientific potential of this project, we will need not only better data distribution and coordination mechanisms, but also improved algorithms, artificial intelligence and ontologies to extract knowledge in an automated way at a scale not yet attempted in science. In this keynote I will present an overview of the SKA project, outline the "big data" challenges the project faces and discuss some of the approaches we are taking to tame the astronomical data deluge we face.

  20. Challenges in the management of community pharmacies in Malaysia

    PubMed Central

    2017-01-01

    Background: The provision of professional pharmacy services by community pharmacists continues to be limited, particularly in low and middle income countries. It was postulated that multiple management challenges faced by community pharmacists contribute to this situation. Objective: The primary aim of the research was to determine the challenges faced in the management of community pharmacies in Sarawak (the largest state in Malaysia), and practical strategies to cope and overcome the challenges. Methods: Semi-structured interviews were carried out with community pharmacists practising in Sarawak. Purposive and snowball sampling were employed to ensure a diverse group of informants. The interviews were audio-recorded and transcribed verbatim, with the resultant data analysed using thematic analysis. Data collection, coding, interpretation were carried out iteratively until theoretical saturation. Results: Twenty respondents from different demographic characteristics were recruited. Six major themes were identified. Management challenges faced by community pharmacists traverse five major domains: market competition, legislative issues, customers’ knowledge and expectations, macroeconomic impacts and operational challenges. Most of these challenges require government intervention to be resolved. In the meantime, improving customer service and expanding the range of professional services were seen as the most viable strategies to cope with existing challenges. The main concern is that current legislative and economic landscape may hinder these strategies. Enactment of dispensing separation and more protective measures against market competition were suggested to alleviate the challenges faced. Conclusion: Numerous management challenges faced by community pharmacists that distract them from delivering professional pharmacy services have been highlighted. Urgent affirmative actions by the government are warranted in supporting community pharmacists to realise and maximise their potentials. PMID:28690697

  1. The modern library: lost and found.

    PubMed Central

    Lindberg, D A

    1996-01-01

    The modern library, a term that was heard frequently in the mid-twentieth century, has fallen into disuse. The over-promotion of computers and all that their enthusiasts promised probably hastened its demise. Today, networking is transforming how libraries provide--and users seek--information. Although the Internet is the natural environment for the health sciences librarian, it is going through growing pains as we face issues of censorship and standards. Today's "modern librarian" must not only be adept at using the Internet but must become familiar with digital information in all its forms--images, full text, and factual data banks. Most important, to stay "modern," today's librarians must embark on a program of lifelong learning that will enable them to make optimum use of the advantages offered by modern technology. PMID:8938334

  2. Recommender System and Web 2.0 Tools to Enhance a Blended Learning Model

    ERIC Educational Resources Information Center

    Hoic-Bozic, Natasa; Dlab, Martina Holenko; Mornar, Vedran

    2016-01-01

    Blended learning models that combine face-to-face and online learning are of great importance in modern higher education. However, their development should be in line with the recent changes in e-learning that emphasize a student-centered approach and use tools available on the Web to support the learning process. This paper presents research on…

  3. Modern Media and Instructional Technology in Vocational Education: Some Experiences of the Diffusion of New Technology in the Adult Education Institutions.

    ERIC Educational Resources Information Center

    Maki-Komsi, Saija; Ropo, Eero

    A study investigated teachers' experiences of educational and cultural change in adult education institutions. The initial assumption of the study was that the institutional shift from traditional teacher-dominated, face-to-face teaching to networked teamwork that emphasizes students' independence is not only a methodological or technological…

  4. Challenges When Introducing Electronic Exam

    ERIC Educational Resources Information Center

    Kuikka, Matti; Kitola, Markus; Laakso, Mikko-Jussi

    2014-01-01

    Time pressures often necessitate the use of more efficient exam tools, such as electronic exams (e-exams), instead of traditional paper exams. However, teachers may face challenges when introducing e-exams in a higher education context. This paper describes what kinds of challenges teachers may face when introducing e-exams, based on experiences…

  5. Bridging the Gap: The Challenges of Employing Entrepreneurial Processes within University Settings

    ERIC Educational Resources Information Center

    Wardale, Dorothy; Lord, Linley

    2016-01-01

    In Australia and elsewhere, universities face increasing pressure to improve research output and quality, particularly through partnerships with industry. This raises interesting challenges for academic staff with considerable industry experience who are "new" to academe. Some of these challenges were faced by the authors who have been…

  6. Confronting Unsuccessful Practices: Repositioning Teacher Identities in English Education

    ERIC Educational Resources Information Center

    Vetter, Amy; Hartman, Shana V.; Reynolds, Jeanie M.

    2016-01-01

    Teacher education programs attempt to prepare preservice teachers for the various challenges faced in the classroom. One particular challenge new teachers face is how to handle unsuccessful practices. This paper argues that confronting ineffective practices require that teachers respond to complex and dynamic challenges, making change difficult…

  7. Challenges Faced by Project Competition Participants and Recommended Solutions

    ERIC Educational Resources Information Center

    Demirel, Turgay; Baydas, Ozlem; Yilmaz, Rabia M.; Goktas, Yuksel

    2013-01-01

    The numbers of project competitions and interest in this kind of competition have been steadily increasing in Turkey. Accordingly, it is important to determine what challenges teachers and students may face while preparing themselves for project competitions, so that recommendations may be made to overcome these challenges. This study investigated…

  8. Human feeding biomechanics: performance, variation, and functional constraints

    PubMed Central

    Dechow, Paul C.; Wang, Qian; Gharpure, Poorva H.; Baab, Karen L.; Smith, Amanda L.; Weber, Gerhard W.; Grosse, Ian R.; Ross, Callum F.; Richmond, Brian G.; Wright, Barth W.; Byron, Craig; Wroe, Stephen; Strait, David S.

    2016-01-01

    The evolution of the modern human (Homo sapiens) cranium is characterized by a reduction in the size of the feeding system, including reductions in the size of the facial skeleton, postcanine teeth, and the muscles involved in biting and chewing. The conventional view hypothesizes that gracilization of the human feeding system is related to a shift toward eating foods that were less mechanically challenging to consume and/or foods that were processed using tools before being ingested. This hypothesis predicts that human feeding systems should not be well-configured to produce forceful bites and that the cranium should be structurally weak. An alternate hypothesis, based on the observation that humans have mechanically efficient jaw adductors, states that the modern human face is adapted to generate and withstand high biting forces. We used finite element analysis (FEA) to test two opposing mechanical hypotheses: that compared to our closest living relative, chimpanzees (Pan troglodytes), the modern human craniofacial skeleton is (1) less well configured, or (2) better configured to generate and withstand high magnitude bite forces. We considered intraspecific variation in our examination of human feeding biomechanics by examining a sample of geographically diverse crania that differed notably in shape. We found that our biomechanical models of human crania had broadly similar mechanical behavior despite their shape variation and were, on average, less structurally stiff than the crania of chimpanzees during unilateral biting when loaded with physiologically-scaled muscle loads. Our results also show that modern humans are efficient producers of bite force, consistent with previous analyses. However, highly tensile reaction forces were generated at the working (biting) side jaw joint during unilateral molar bites in which the chewing muscles were recruited with bilateral symmetry. In life, such a configuration would have increased the risk of joint dislocation and constrained the maximum recruitment levels of the masticatory muscles on the balancing (non-biting) side of the head. Our results do not necessarily conflict with the hypothesis that anterior tooth (incisors, canines, premolars) biting could have been selectively important in humans, although the reduced size of the premolars in humans has been shown to increase the risk of tooth crown fracture. We interpret our results to suggest that human craniofacial evolution was probably not driven by selection for high magnitude unilateral biting, and that increased masticatory muscle efficiency in humans is likely to be a secondary byproduct of selection for some function unrelated to forceful biting behaviors. These results are consistent with the hypothesis that a shift to softer foods and/or the innovation of pre-oral food processing techniques relaxed selective pressures maintaining craniofacial features that favor forceful biting and chewing behaviors, leading to the characteristically small and gracile faces of modern humans. PMID:27547550

  9. Virtual Academic Community: Online Education Instructors' Social Presence in Association with Freshman Composition Students' Critical Thinking and Argumentation

    ERIC Educational Resources Information Center

    Paquette, Paige Fuller

    2009-01-01

    There is much literature addressing challenges face-to-face freshman composition instructors encounter in developing college courses that foster critical thinking skills crucial to developing written argument. Composition instructors may face challenges in teaching students that writing is a means of making meaning, there are many different…

  10. The Challenges of Adopting the Learning Organisation Philosophy in a Singapore School

    ERIC Educational Resources Information Center

    Retna, Kala S.; Tee, Ng Pak

    2006-01-01

    Purpose: To report on a case study that examines how the Learning Organisation (LO) concept can be applied in a Singapore school and the challenges that the school faces in the process. Design/methodology/approach: A qualitative research inquiry was adopted using ethnographic methods. Data includes in-depth face-to-face interviews, observation of…

  11. Challenges Faced by Undergraduate Military Students at American Public University System

    ERIC Educational Resources Information Center

    Machuca, Ana; Torres, Karin; Morris, Pamela; Whitley, William

    2014-01-01

    This paper will summarize some of challenges faced by military students enrolled in an associate and bachelors online program at American Public University System (APUS). The survey results on which the study is based exposed the following problems faced by military personnel: 48.7% had difficulties working around military obligations, 33.3%…

  12. Craft, money and mercy: an apothecary's self-portrait in sixteenth-century Bologna.

    PubMed

    Di Gennaro Splendore, Barbara

    2017-04-01

    The apothecary occupied a liminal position in early modern society between profit and healing. Finding ways to distance their public image from trade was a common problem for apothecaries across Europe. This article uses the case of a Bolognese apothecary, Filippo Pastarino, to address the question of how early modern apothecaries chose to represent themselves to political authorities and to the wider public. 'Mercy', alongside 'craft', was a pillar of apothecaries' social identity. By contrast, no matter how central financial transactions ('money') were to their activity, apothecaries did not want to be perceived as merchants. Thus, the assistance and advice apothecaries provided to patients and customers resulted as central aspects of their social role. In this context, Bolognese apothecaries aimed to defend their current status, which had been challenged by naturalist Ulysses Aldrovandi, city authorities and local monasteries. However, Pastarino's claims can also be seen as antecedents to the self-legitimizing strategy that seventeenth-century artisans deployed when faced with the need to enhance their new status as natural philosophers. The present study attributes a name, a date of birth and a shop to Filippo Pastarino, revising previous interpretations. More broadly, by focusing on how these artisans defended their position in the city it enriches our understanding of the self-representation of apothecaries.

  13. Osteometric sorting of skeletal elements from a sample of modern Colombians: a pilot study.

    PubMed

    Rodríguez, Juan Manuel Guerrero; Hackman, Lucina; Martínez, Wendy; Medina, César Sanabria

    2016-03-01

    The Colombian armed conflict has been catalogued not only as the longest civil war in the western hemisphere, but also as having one of the highest indexes of missing persons. Among the several challenges faced by forensic practitioners in Colombia, the commingling of human remains has been recognised as one of the most difficult to approach. The method of osteometric sorting described by Byrd and Adams and Byrd (2008) has proven relevant as a powerful tool to aid in the reassociation process of skeletal structures. The aim of this research was to evaluate the three osteometric sorting models developed by Byrd (2008) (paired elements, articulating bone portions and other bone portions) in a sample of modern Colombian individuals. A set of 39 linear measurements was recorded from a sample of 100 individuals (47 females and 53 males aged between 20 and 74 and 18 and 77 years, respectively), which was used to create a reference sample database. A different subset of eight individuals (five females aged between 23 and 48 years, and three males aged between 27 and 43 years) was employed to randomly create six small-scale commingled assemblages for the purposes of testing the osteometric sorting models. Results demonstrate that this method has significant potential for use in the Colombian forensic context.

  14. Strategies for target identification of antimicrobial natural products.

    PubMed

    Farha, Maya A; Brown, Eric D

    2016-05-04

    Covering: 2000 to 2015Despite a pervasive decline in natural product research at many pharmaceutical companies over the last two decades, natural products have undeniably been a prolific and unsurpassed source for new lead antibacterial compounds. Due to their inherent complexity, natural extracts face several hurdles in high-throughout discovery programs, including target identification. Target identification and validation is a crucial process for advancing hits through the discovery pipeline, but has remained a major bottleneck. In the case of natural products, extremely low yields and limited compound supply further impede the process. Here, we review the wealth of target identification strategies that have been proposed and implemented for the characterization of novel antibacterials. Traditionally, these have included genomic and biochemical-based approaches, which, in recent years, have been improved with modern-day technology and better honed for natural product discovery. Further, we discuss the more recent innovative approaches for uncovering the target of new antibacterial natural products, which have resulted from modern advances in chemical biology tools. Finally, we present unique screening platforms implemented to streamline the process of target identification. The different innovative methods to respond to the challenge of characterizing the mode of action for antibacterial natural products have cumulatively built useful frameworks that may advocate a renovated interest in natural product drug discovery programs.

  15. Applying the Rasch Model to Measure Acculturation Challenges Faced by Saudi Female Students in the United States

    ERIC Educational Resources Information Center

    Hakami, Samah Mohammed

    2012-01-01

    The purpose of this study was to explore the major acculturation challenges faced by Saudi female students who study in the U.S. and to develop a scale to measure potential acculturation challenges. The construction of the scale was based on a table of specification that included nine domains of possible acculturation challenges: (a)…

  16. Use of Foodomics for Control of Food Processing and Assessing of Food Safety.

    PubMed

    Josić, D; Peršurić, Ž; Rešetar, D; Martinović, T; Saftić, L; Kraljević Pavelić, S

    Food chain, food safety, and food-processing sectors face new challenges due to globalization of food chain and changes in the modern consumer preferences. In addition, gradually increasing microbial resistance, changes in climate, and human errors in food handling remain a pending barrier for the efficient global food safety management. Consequently, a need for development, validation, and implementation of rapid, sensitive, and accurate methods for assessment of food safety often termed as foodomics methods is required. Even though, the growing role of these high-throughput foodomic methods based on genomic, transcriptomic, proteomic, and metabolomic techniques has yet to be completely acknowledged by the regulatory agencies and bodies. The sensitivity and accuracy of these methods are superior to previously used standard analytical procedures and new methods are suitable to address a number of novel requirements posed by the food production sector and global food market. © 2017 Elsevier Inc. All rights reserved.

  17. [Research progress of genetic engineering on medicinal plants].

    PubMed

    Teng, Zhong-qiu; Shen, Ye

    2015-02-01

    The application of genetic engineering technology in modern agriculture shows its outstanding role in dealing with food shortage. Traditional medicinal plant cultivation and collection have also faced with challenges, such as lack of resources, deterioration of environment, germplasm of recession and a series of problems. Genetic engineering can be used to improve the disease resistance, insect resistance, herbicides resistant ability of medicinal plant, also can improve the medicinal plant yield and increase the content of active substances in medicinal plants. Thus, the potent biotechnology can play an important role in protection and large area planting of medicinal plants. In the development of medicinal plant genetic engineering, the safety of transgenic medicinal plants should also be paid attention to. A set of scientific safety evaluation and judgment standard which is suitable for transgenic medicinal plants should be established based on the recognition of the particularity of medicinal plants.

  18. Prospects of application of additive technologies for increasing the efficiency of impeller machines

    NASA Astrophysics Data System (ADS)

    Belova, O. V.; Borisov, Yu. A.

    2017-08-01

    Impeller machine is a device in which the flow path carries out the supply (or retraction) of mechanical energy to the flow of a working fluid passing through the machine. To increase the efficiency of impeller machines, it is necessary to use design modern technologies, namely the use of numerical methods for conducting research in the field of gas dynamics, as well as additive manufacturing (AM) for the of both prototypes and production model. AM technologies are deservedly rightly called revolutionary because they give unique possibility for manufacturing products, creating perfect forms, both light and durable. The designers face the challenge of developing a new design methodology, since AM allows the use of the concept of "Complexity For Free". The "Complexity For Free" conception is based on: complexity of the form; hierarchical complexity; complexity of the material; functional complexity. The new technical items design method according to a functional principle is also investigated.

  19. Disease prevention--should we target obesity or sedentary lifestyle?

    PubMed

    Charansonney, Olivier L; Després, Jean-Pierre

    2010-08-01

    Obesity is a major health challenge facing the modern world. Some evidence points to obesity itself as the main driver of premature mortality. We propose that this view is oversimplified. For example, high levels of physical activity and cardiorespiratory fitness are associated with lower mortality, even in those who are overweight or obese. To address this issue, we combine epidemiological and physiological evidence in a new paradigm that integrates excess calorie intake, sedentary behavior, and a maladaptive response to stress. Human physiology is optimized to allow large distances to be covered on foot every day in order to find enough food to sustain brain metabolism. Furthermore, when the body is immobilized by an injury, it triggers efficient life-saving metabolic and inflammatory responses. Both these critical adaptations are, however, confounded by a sedentary lifestyle. The implications of these issues for clinical trial design and epidemiologic data analysis are discussed in this article.

  20. Studying the Past for the Future: Managing Modern Biodiversity from Historic and Prehistoric Data

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Foster, Professor Thomas; Olsen, Lisa M; Dale, Virginia H

    Management of biodiversity and anthropogenic effects on the environment are some of the most difficult challenges facing humans today. In this paper, we describe how archaeological, historical, and ecological data can be combined to identify metrics of ecological change. Archaeological surveys, historic witness tree data, analysis of ancient pollen, and recent satellite imagery are combined to create indicators of change that are useable by modem environmental managers at Fort Benning Military Reservation in Georgia and Alabama in the United States. Archaeological data were collected at 30 meter intervals, historic vegetation data were collected from early nineteenth century survey maps, andmore » ancient pollen and charcoal were collected from soil cores in lakes. We show how data sets collected with disparate goals from anthropology and ecology can be applied to make policy decisions about environmental management.« less

  1. Work process and task-based design of intelligent assistance systems in German textile industry

    NASA Astrophysics Data System (ADS)

    Löhrer, M.; Ziesen, N.; Altepost, A.; Saggiomo, M.; Gloy, Y. S.

    2017-10-01

    The mid-sized embossed German textile industry must face social challenges e.g. demographic change or technical changing processes. Interaction with intelligent systems (on machines) and increasing automation changes processes, working structures and employees’ tasks on all levels. Work contents are getting more complex, resulting in the necessity for diversified and enhanced competencies. Mobile devices like tablets or smartphones are increasingly finding their way into the workplace. Employees who grew up with new forms of media have certain advantages regarding the usage of modern technologies compared to older employees. Therefore, it is necessary to design new systems which help to adapt the competencies of both younger and older employees to new automated production processes in the digital work environment. The key to successful integration of technical assistance systems is user-orientated design and development that includes concepts for competency development under consideration of, e.g., ethical and legal aspects.

  2. An analysis of the development and application of plant protection UAV based on advanced materials

    NASA Astrophysics Data System (ADS)

    Huang, Yuan-hui; Wei, Neng; Quan, Zhi-cheng; Huang, Yu-rong

    2018-06-01

    The development and application of a number of advanced materials plant protection unmanned aerial vehicle (UAV) is an important part of the comprehensive production of agricultural modernization. The paper is taken as an example of Guangxi No. 1 agricultural service aviation science and Technology Co., Ltd. This paper introduces the internal and external environment of the research and development of the plant protection UAV for the advanced materials of the company. The external environment focuses on the role of the plant protection UAV on the development of the agricultural mechanization; the internal environment focuses on the advantages of the UAV in technology research, market promotion and application, which is imperative. Finally, according to the background of the whole industry, we put forward some suggestions for the developing opportunities and challenges faced by plant protection UAV, hoping to proving some ideas for operators, experts and scholars engaged in agricultural industry.

  3. Nature or Artifice? Grafting in Early Modern Surgery and Agronomy.

    PubMed

    Savoia, Paolo

    2017-01-01

    In 1597, Gaspare Tagliacozzi published a famous two-volume book on “plastic surgery.” The reconstructive technique he described was based on grafting skin taken from the arm onto the mutilated parts of the patient's damaged face – especially noses. This paper focuses on techniques of grafting, the “culture of grafting,” and the relationships between surgery and plant sciences in the sixteenth century. By describing the fascination with grafting in surgery, natural history, gardening, and agronomy the paper argues that grafting techniques were subject to delicate issues: to what extent it was morally acceptable to deceive the eye with artificial entities? and what was the status of the product of a surgical procedure that challenged the traditional natural/artificial distinction? Finally, this paper shows how in the seventeenth century grafting survived the crisis of Galenism by discussing the role it played in teratology and in controversies on the uses the new mechanistic anatomy.

  4. “He Must Die or Go Mad in This Place”:

    PubMed Central

    Cox, Catherine; Marland, Hilary

    2018-01-01

    summary The relationship between prisons and mental illness has preoccupied prison administrators, physicians, and reformers from the establishment of the modern prison service in the nineteenth century to the current day. Here we take the case of Pentonville Model Prison, established in 1842 with the aim of reforming convicts through religious exhortation, rigorous discipline and training, and the imposition of separate confinement in its most extreme form. Our article demonstrates how following the introduction of separate confinement, the prison chaplains rather than the medical officers took a lead role in managing the minds of convicts. However, instead of reforming and improving prisoners’ minds, Pentonville became associated with high rates of mental disorder, challenging the institution’s regime and reputation. We explore the role of chaplains, doctors, and other prison officers in debating, disputing, and managing cases of mental breakdown and the dismantling of separate confinement in the face of mounting criticism. PMID:29681551

  5. Fashion sketch design by interactive genetic algorithms

    NASA Astrophysics Data System (ADS)

    Mok, P. Y.; Wang, X. X.; Xu, J.; Kwok, Y. L.

    2012-11-01

    Computer aided design is vitally important for the modern industry, particularly for the creative industry. Fashion industry faced intensive challenges to shorten the product development process. In this paper, a methodology is proposed for sketch design based on interactive genetic algorithms. The sketch design system consists of a sketch design model, a database and a multi-stage sketch design engine. First, a sketch design model is developed based on the knowledge of fashion design to describe fashion product characteristics by using parameters. Second, a database is built based on the proposed sketch design model to define general style elements. Third, a multi-stage sketch design engine is used to construct the design. Moreover, an interactive genetic algorithm (IGA) is used to accelerate the sketch design process. The experimental results have demonstrated that the proposed method is effective in helping laypersons achieve satisfied fashion design sketches.

  6. The Anatomy of Teleneurosurgery in China

    PubMed Central

    Gao, Xiaohong

    2011-01-01

    With its huge population and vast territory, China faces a great challenge in providing modern advanced health care services to all parts of the country. The advances of information communication technologies (ICTs) and the advent of internet have revolutionised the means in the delivery of healthcare via telemedicine to remote and underserved populations, which to a certain extent has been very well exploited in China, especially where 70% peasants residing in the rural areas. This paper reviews the latest development in telemedicine infrastructure in China with the focus on the development of teleneurosurgery, drawing from the results gained from a 3-year networking project between Europe and China on telemedicine (TIME, 2005–2007) funded by European Commission under Asia ICT programme, with an aim to shape up envisages of future medical care in China. Comparison with its counterparts in Europe is also addressed. PMID:21941536

  7. Fuzzy Entropy Method for Quantifying Supply Chain Networks Complexity

    NASA Astrophysics Data System (ADS)

    Zhang, Jihui; Xu, Junqin

    Supply chain is a special kind of complex network. Its complexity and uncertainty makes it very difficult to control and manage. Supply chains are faced with a rising complexity of products, structures, and processes. Because of the strong link between a supply chain’s complexity and its efficiency the supply chain complexity management becomes a major challenge of today’s business management. The aim of this paper is to quantify the complexity and organization level of an industrial network working towards the development of a ‘Supply Chain Network Analysis’ (SCNA). By measuring flows of goods and interaction costs between different sectors of activity within the supply chain borders, a network of flows is built and successively investigated by network analysis. The result of this study shows that our approach can provide an interesting conceptual perspective in which the modern supply network can be framed, and that network analysis can handle these issues in practice.

  8. Key aspects of the Novartis compound collection enhancement project for the compilation of a comprehensive chemogenomics drug discovery screening collection.

    PubMed

    Jacoby, Edgar; Schuffenhauer, Ansgar; Popov, Maxim; Azzaoui, Kamal; Havill, Benjamin; Schopfer, Ulrich; Engeloch, Caroline; Stanek, Jaroslav; Acklin, Pierre; Rigollier, Pascal; Stoll, Friederike; Koch, Guido; Meier, Peter; Orain, David; Giger, Rudolph; Hinrichs, Jürgen; Malagu, Karine; Zimmermann, Jürg; Roth, Hans-Joerg

    2005-01-01

    The NIBR (Novartis Institutes for BioMedical Research) compound collection enrichment and enhancement project integrates corporate internal combinatorial compound synthesis and external compound acquisition activities in order to build up a comprehensive screening collection for a modern drug discovery organization. The main purpose of the screening collection is to supply the Novartis drug discovery pipeline with hit-to-lead compounds for today's and the future's portfolio of drug discovery programs, and to provide tool compounds for the chemogenomics investigation of novel biological pathways and circuits. As such, it integrates designed focused and diversity-based compound sets from the synthetic and natural paradigms able to cope with druggable and currently deemed undruggable targets and molecular interaction modes. Herein, we will summarize together with new trends published in the literature, scientific challenges faced and key approaches taken at NIBR to match the chemical and biological spaces.

  9. The orthodontic-periodontic interrelationship in integrated treatment challenges: a systematic review.

    PubMed

    Gkantidis, N; Christou, P; Topouzelis, N

    2010-05-01

    Orthodontic treatment aims at providing an acceptable functional and aesthetic occlusion with appropriate tooth movements. These movements are strongly related to interactions of teeth with their supportive periodontal tissues. In recent years, because of the increased number of adult patients seeking orthodontic treatment, orthodontists frequently face patients with periodontal problems. Aesthetic considerations, like uneven gingival margins or functional problems resulting from inflammatory periodontal diseases should be considered in orthodontic treatment planning. Furthermore, in cases with severe periodontitis, orthodontics may improve the possibilities of saving and restoring a deteriorated dentition. In modern clinical practice, the contribution of the orthodontist, the periodontist and the general dentist is essential for optimized treatment outcomes. The purpose of this systematic review is to highlight the relationship between orthodontics and periodontics in clinical practice and to improve the level of cooperation between dental practitioners. Potentials and limitations that derive from the interdisciplinary approach of complex orthodontic-periodontal clinical problems are discussed.

  10. Institutional Support | Grid Modernization | NREL

    Science.gov Websites

    the challenges posed by grid modernization. Photo of two people standing in front of a display showing results from a grid study. The demand for objective technical assistance and information on grid related to grid modernization and increasing deployment of distributed energy and renewable resources. As

  11. Challenges for Novice School Leaders: Facing Today's Issues in School Administration

    ERIC Educational Resources Information Center

    Beam, Andrea P.; Claxton, Russell L.; Smith, Samuel J.

    2016-01-01

    Challenges for novice school leaders evolve as information is managed differently and as societal and regulatory expectations change. This study addresses unique challenges faced by practicing school administrators (n = 159) during their first three years in a school leadership position. It focuses on their perceptions, how perceptions of present…

  12. Leading Schools Facing Challenging Circumstances: Some Insights from Western Australia

    ERIC Educational Resources Information Center

    Gillett, Jonathan; Clarke, Simon; O'Donoghue, Tom

    2016-01-01

    This paper examines leadership strategies that are most likely to engender success in schools that may be defined as facing challenging circumstances. First, it presents an overview of the relevant literature in order to illustrate distinctive challenges that tend to be encountered in these environments, as well as strategies that are adopted for…

  13. The Value of Conceptual Models in Coping with Complexity and Interdisciplinarity in Environmental Sciences Education

    ERIC Educational Resources Information Center

    Fortuin, Karen P. J.; van Koppen, C. S. A.; Leemans, Rik

    2011-01-01

    Conceptual models are useful for facing the challenges of environmental sciences curriculum and course developers and students. These challenges are inherent to the interdisciplinary and problem-oriented character of environmental sciences curricula. In this article, we review the merits of conceptual models in facing these challenges. These…

  14. CAEP Challenges for a Mid-South U.S. College Teacher Education Program

    ERIC Educational Resources Information Center

    Moffett, David W.

    2016-01-01

    What are the challenges faced by a mid-south liberal arts college teacher education program, in its attempt to successfully meet the new Council for the Accreditation of Educator Preparation (CAEP) accreditation requirements? The Investigator studied the Educator Program Provider (EPP) during academic year 2015-2016. The challenges faced by the…

  15. Challenges of Attending E-Learning Studies in Nigeria

    ERIC Educational Resources Information Center

    Bugi, Stephan Z.

    2012-01-01

    This study set out to find out what challenges the E-leaner faces in the Nigerian environment. Survey research design was used to obtain the opinion of 200 randomly selected E-learners in Kaduna metropolis. Their responses revealed that the most prominent challenges they face are, Inadequate Power supply, Internet connectivity problems, Efficacy…

  16. Challenges and Instructional Approaches Impacting the Literacy Performance of English Language Learners

    ERIC Educational Resources Information Center

    Markham, Paul L.; Gordon, Karen E.

    2007-01-01

    For English Language Learners (ELLs), the process of becoming literate in English is daunting. Not only are these students faced with the same literacy challenges faced by native English-speaking students, but they are also challenged with extensive diversity issues relating to substantial differences in linguistic, cultural, and academic…

  17. The Evolutionary Paradox of Tooth Wear: Simply Destruction or Inevitable Adaptation?

    PubMed Central

    Benazzi, Stefano; Nguyen, Huynh Nhu; Schulz, Dieter; Grosse, Ian R.; Gruppioni, Giorgio; Hublin, Jean-Jacques; Kullmer, Ottmar

    2013-01-01

    Over the last century, humans from industrialized societies have witnessed a radical increase in some dental diseases. A severe problem concerns the loss of dental materials (enamel and dentine) at the buccal cervical region of the tooth. This “modern-day” pathology, called non-carious cervical lesions (NCCLs), is ubiquitous and worldwide spread, but is very sporadic in modern humans from pre-industrialized societies. Scholars believe that several factors are involved, but the real dynamics behind this pathology are far from being understood. Here we use an engineering approach, finite element analysis (FEA), to suggest that the lack of dental wear, characteristic of industrialized societies, might be a major factor leading to NCCLs. Occlusal loads were applied to high resolution finite element models of lower second premolars (P2) to demonstrate that slightly worn P2s envisage high tensile stresses in the buccal cervical region, but when worn down artificially in the laboratory the pattern of stress distribution changes and the tensile stresses decrease, matching the results obtained in naturally worn P2s. In the modern industrialized world, individuals at advanced ages show very moderate dental wear when compared to past societies, and teeth are exposed to high tensile stresses at the buccal cervical region for decades longer. This is the most likely mechanism explaining enamel loss in the cervical region, and may favor the activity of other disruptive processes such as biocorrosion. Because of the lack of dental abrasion, our masticatory apparatus faces new challenges that can only be understood in an evolutionary perspective. PMID:23638020

  18. Young persons with visual impairment: challenges of participation.

    PubMed

    Salminen, Anna-Liisa; Karhula, Maarit E

    2014-07-01

    To describe the challenges to activity and participation faced by young people with visual impairment within the framework of the International Classification of Functioning (ICF). 14 young persons (aged 16-22 years) with visual impairment and their parents (n = 22) participated in the study. The Canadian Occupational Performance Measure (COPM) was used to describe challenges of participation as perceived by the young persons themselves. Individual interviews with the young persons and their parents were used to investigate in more depth the challenges the young persons face with regard to participation. Young persons with visual impairment face challenges to participation most frequently with regard to mobility, domestic life, interpersonal interaction and relationships, major life areas, and leisure activities. The environment in which they live has a central role as a barrier or facilitator of participation. The challenges related to activities and participation that young persons with visual impairment face are diverse. It is important that these challenges are assessed individually and with the help of subjective measures. Serving as a broad framework for classifying the data, the ICF proved to be a useful tool, but used strictly at category level it may limit the coding of data and narrow interpretation.

  19. Becoming a nurse faculty leader: facing challenges through reflecting, persevering and relating in new ways.

    PubMed

    Horton-Deutsch, Sara; Young, Patricia K; Nelson, Kristine A

    2010-05-01

    The aim of the present study was to explore the experience of becoming a nurse faculty leader. In a recent interpretation of 23 interviews conducted with nurse faculty leaders from across the United States about their experiences of becoming a leader three themes were identified: being thrust into leadership, taking risks and facing challenges. This interpretive phenomenological study further explicates three aspects of how nurse educators faced challenges in becoming and serving as a leader. Facing challenges meant reflecting, persevering through difficulties and learning to relate to others in new ways. Exemplars of participant experiences are provided for concreteness, to assist readers in determining how findings resonate with their own experience and how they can actualize this resonance in their own leadership practice. In the present study, reflecting, persevering through difficulties and learning to relate with others in a new way was how leaders faced challenges. Leadership development opportunities that facilitate self-exploration, caring and thoughtful interactions with others and values clarification serve as the foundation for becoming a nurse faculty leader who is, in turn, able to build leadership capacity in other individuals and organizations.

  20. Development and application of modern agricultural biotechnology in Botswana: The potentials, opportunities and challenges

    PubMed Central

    Batlang, Utlwang; Tsurupe, Gorata; Segwagwe, Amogelang; Obopile, Motshwari

    2014-01-01

    In Botswana, approximately 40% of the population live in rural areas and derive most of their livelihood from agriculture by keeping livestock and practising arable farming. Due to the nature of their farming practises livestock and crops are exposed to diseases and environmental stresses. These challenges offer opportunities for application of biotechnology to develop adaptable materials to the country's environment. On the other hand, the perceived risk of genetically modified organisms (GMOs) has dimmed the promise of the technology for its application in agriculture. This calls for a holistic approach to the application of biotechnology to address issues of biosafety of GMOs. We have therefore assessed the potentials, challenges and opportunities to apply biotechnology with specific emphasis on agriculture, taking cognisance of requirement for its research, development and application in research and teaching institutions. In order to achieve this, resource availability, infrastructure, human and laboratory requirements were analyzed. The analysis revealed that the country has the capacity to carry out research in biotechnology in the development and production of genetically modified crops for food and fodder crops. These will include gene discovery, genetic transformation and development of systems to comply with the world regulatory framework on biosafety. In view of the challenges facing the country in agriculture, first generation biotech crops could be released for production. Novel GM products for development may include disease diagnosis kits, animal disease vaccines, and nutrient use efficiency, drought, and pest and disease resistant food and fodder crops. PMID:25437237

  1. Development and application of modern agricultural biotechnology in Botswana: the potentials, opportunities and challenges.

    PubMed

    Batlang, Utlwang; Tsurupe, Gorata; Segwagwe, Amogelang; Obopile, Motshwari

    2014-07-03

    In Botswana, approximately 40% of the population live in rural areas and derive most of their livelihood from agriculture by keeping livestock and practising arable farming. Due to the nature of their farming practises livestock and crops are exposed to diseases and environmental stresses. These challenges offer opportunities for application of biotechnology to develop adaptable materials to the country's environment. On the other hand, the perceived risk of genetically modified organisms (GMOs) has dimmed the promise of the technology for its application in agriculture. This calls for a holistic approach to the application of biotechnology to address issues of biosafety of GMOs. We have therefore assessed the potentials, challenges and opportunities to apply biotechnology with specific emphasis on agriculture, taking cognisance of requirement for its research, development and application in research and teaching institutions. In order to achieve this, resource availability, infrastructure, human and laboratory requirements were analyzed. The analysis revealed that the country has the capacity to carry out research in biotechnology in the development and production of genetically modified crops for food and fodder crops. These will include gene discovery, genetic transformation and development of systems to comply with the world regulatory framework on biosafety. In view of the challenges facing the country in agriculture, first generation biotech crops could be released for production. Novel GM products for development may include disease diagnosis kits, animal disease vaccines, and nutrient use efficiency, drought, and pest and disease resistant food and fodder crops.

  2. Focusing a Transition: Challenges Facing the New Administration

    DTIC Science & Technology

    2016-09-01

    FOCUSING A TRANSITION Challenges Facing the New Administration A Report by the Defense Business Board 2016 This report, DBB Report FY16-5, is a ...Facing the New Administration A Report by the Defense Business Board 5 Table of Contents INTRODUCTION...While reviewing the budget, the team should develop a list of items to propose for immediate termination. The Board offers the following

  3. Nursing education development in China (1887-1949): influences on contemporary nursing.

    PubMed

    Yan, Z; Li, J An; McDonald, T

    2014-09-01

    On 8 May 2013, the Chinese Nursing Association joined the International Council of Nurses. It is hoped that by sharing the history of nursing in China, scholars globally can incorporate into current thinking the challenges that Chinese nurses have faced in pursuing educational development and professional acknowledgement. To review the history of nurse education in China between 1887 and 1949 and summarize events marking its development; and to provide historical references for considering contemporary nurse education and discipline development in China. Content analysis using bibliometric and historical research methods on available documentation sources. Milestone events were listed and their historical significance analysed. Nurse education development during this period was affected by three major influences: (1) international nursing collaboration and involvement with Chinese nursing in China and abroad, (2) the determination of leaders to develop nursing as a unique and ethical profession, and (3) the pressure of war and civilian need on the focus of nursing development in China. The development of nurse education in China occurred within an environment of social change, war and international collaboration. Throughout the Modern China period (1887-1949), nursing leadership has guided the growth of nurse education to be responsive to individual and community needs as well as ensuring nurse accountability for conduct and nursing practice. Contemporary Chinese nursing and education owes much to those throughout the Modern China period, who laid the foundations that support the current position and status of nursing. The study displays the benefits and challenges of participation in policy and forums that help nurse scholars and practitioners understand the development of nurse education in China. © 2014 International Council of Nurses.

  4. Defense Infrastructure: Challenges Increase Risks for Providing Timely Infrastructure Support for Army Installations Expecting Substantial Personnel Growth

    DTIC Science & Technology

    2007-09-01

    Office Why GAO Did This Study Highlights Accountability Integrity Reliability September 2007 DEFENSE INFRASTRUCTURE Challenges Increase Risks for...authority to conduct evaluations on his own initiative. It addresses (1) the challenges and associated risks the Army faces in providing for timely...but it faces several complex implementation challenges that risk late provision of needed infrastructure to adequately support incoming personnel

  5. A qualitative exploration of the major challenges facing pharmacovigilance in Saudi Arabia.

    PubMed

    Aljadhey, Hisham; Mahmoud, Mansour A; Alshammari, Thamir M; Al-Dhaeefi, Mohammed; Le Louet, Herve; Perez-Gutthann, Susana; Pitts, Peter J

    2015-09-01

    To explore the challenges facing pharmacovigilance in Saudi Arabia and formulate recommendations to improve it from the perspective of healthcare professionals in Saudi Arabia. This was a qualitative study of 4 focus group discussions with pharmacists, physicians, and academicians held under the auspices of the King Saud University School of Pharmacy and the Center for Medicine in the Public Interest, Riyadh, Saudi Arabia. A total of 29 eligible healthcare professionals were invited to participate in the discussion. The predefined themes of the study were the current practice and major challenges facing pharmacovigilance in regulatory bodies, hospitals, the community, and academia, as well as recommendations to improve pharmacovigilance practice.  Of the 29 participants invited, 27 attended the discussion. Challenges facing regulatory bodies included complicated adverse drug reactions (ADR) reporting forms, lack of feedback on ADRs submitted to the Saudi Food and Drug Authority, lack of decisions from the local authority to withdraw medications, and lack of data on pharmacovigilance. The challenges to pharmacovigilance in hospitals included the lack of knowledge of the significance of ADR reporting, workload, blaming culture, and lack of collaboration between regulatory bodies and hospitals. However, challenges facing pharmaceutical industries included the lack of drug manufacturers in Saudi Arabia and lack of interest in pharmacovigilance. Recommendations to improve pharmacovigilance included the need for communication, stronger regulatory requirements, the need for research, the need for unified ADRs reporting, and continuous education and training.  The study has identified the challenges facing pharmacovigilance in Saudi Arabia and made certain recommendations to overcome them. These recommendations might be helpful for regulatory bodies to enhance spontaneous reporting and promote pharmacovigilance.

  6. Health Economics at the Crossroads of Centuries – From the Past to the Future

    PubMed Central

    Jakovljevic, Mihajlo (Michael); Ogura, Seiritsu

    2016-01-01

    Health economics, as an interdisciplinary science, has experienced exceptionally bold evolution through the past eight decades. Generations of committed scholars have built up huge body of knowledge and developed a set of methodological tools to assist health-care authorities with resource allocation process. Following its conception at the US National Bureau of Economic Research and Ivy League US Universities, this science has spread across the Globe. It has adapted to a myriad of local conditions and needs of the national health systems with diverse historical legacies, medical services provision, and financing patterns. Challenge of financial sustainability facing modern day health systems remains primarily attributable to population aging, prosperity diseases, large scale migrations, rapid urbanization, and technological innovation in medicine. Despite promising developments in developing countries with emerging BRICS markets on the lead, rising out-of-pocket health spending continues to threaten affordability of medical care. Universal health coverage extension will likely remain serious challenge even for some of the most advanced OECD nations. These complex circumstances create strong drivers for inevitable further development of health economics. We believe that this interdisciplinary health science shall leave long-lasting blue print to be visible for decades to come. PMID:27376055

  7. Wireless sensors and sensor networks for homeland security applications.

    PubMed

    Potyrailo, Radislav A; Nagraj, Nandini; Surman, Cheryl; Boudries, Hacene; Lai, Hanh; Slocik, Joseph M; Kelley-Loughnane, Nancy; Naik, Rajesh R

    2012-11-01

    New sensor technologies for homeland security applications must meet the key requirements of sensitivity to detect agents below risk levels, selectivity to provide minimal false-alarm rates, and response speed to operate in high throughput environments, such as airports, sea ports, and other public places. Chemical detection using existing sensor systems is facing a major challenge of selectivity. In this review, we provide a brief summary of chemical threats of homeland security importance; focus in detail on modern concepts in chemical sensing; examine the origins of the most significant unmet needs in existing chemical sensors; and, analyze opportunities, specific requirements, and challenges for wireless chemical sensors and wireless sensor networks (WSNs). We further review a new approach for selective chemical sensing that involves the combination of a sensing material that has different response mechanisms to different species of interest, with a transducer that has a multi-variable signal-transduction ability. This new selective chemical-sensing approach was realized using an attractive ubiquitous platform of battery-free passive radio-frequency identification (RFID) tags adapted for chemical sensing. We illustrate the performance of RFID sensors developed in measurements of toxic industrial materials, humidity-independent detection of toxic vapors, and detection of chemical-agent simulants, explosives, and strong oxidizers.

  8. Marshall Team Recreates Goddard Rocket

    NASA Technical Reports Server (NTRS)

    2003-01-01

    In honor of the Centernial of Flight celebration and commissioned by the American Institute of Aeronautics and Astronautics (AIAA), a team of engineers from Marshall Space Flight Center (MSFC) built a replica of the first liquid-fueled rocket. The original rocket, designed and built by rocket engineering pioneer Robert H. Goddard in 1926, opened the door to modern rocketry. Goddard's rocket reached an altitude of 41 feet while its flight lasted only 2.5 seconds. The Marshall design team's plan was to stay as close as possible to an authentic reconstruction of Goddard's rocket. The same propellants were used - liquid oxygen and gasoline - as available during Goddard's initial testing and firing. The team also tried to construct the replica using the original materials and design to the greatest extent possible. By purposely using less advanced techniques and materials than many that are available today, the team encountered numerous technical challenges in testing the functional hardware. There were no original blueprints or drawings, only photographs and notes. However, this faithful adherence to historical accuracy has also allowed the team to experience many of the same challenges Goddard faced 77 years ago, and more fully appreciate the genius of this extraordinary man. The replica will undergo ground tests at MSFC this summer.

  9. Around Marshall

    NASA Image and Video Library

    2003-07-01

    In honor of the Centernial of Flight celebration and commissioned by the American Institute of Aeronautics and Astronautics (AIAA), a team of engineers from Marshall Space Flight Center (MSFC) built a replica of the first liquid-fueled rocket. The original rocket, designed and built by rocket engineering pioneer Robert H. Goddard in 1926, opened the door to modern rocketry. Goddard's rocket reached an altitude of 41 feet while its flight lasted only 2.5 seconds. The Marshall design team's plan was to stay as close as possible to an authentic reconstruction of Goddard's rocket. The same propellants were used - liquid oxygen and gasoline - as available during Goddard's initial testing and firing. The team also tried to construct the replica using the original materials and design to the greatest extent possible. By purposely using less advanced techniques and materials than many that are available today, the team encountered numerous technical challenges in testing the functional hardware. There were no original blueprints or drawings, only photographs and notes. However, this faithful adherence to historical accuracy has also allowed the team to experience many of the same challenges Goddard faced 77 years ago, and more fully appreciate the genius of this extraordinary man. The replica will undergo ground tests at MSFC this summer.

  10. Health Economics at the Crossroads of Centuries - From the Past to the Future.

    PubMed

    Jakovljevic, Mihajlo Michael; Ogura, Seiritsu

    2016-01-01

    Health economics, as an interdisciplinary science, has experienced exceptionally bold evolution through the past eight decades. Generations of committed scholars have built up huge body of knowledge and developed a set of methodological tools to assist health-care authorities with resource allocation process. Following its conception at the US National Bureau of Economic Research and Ivy League US Universities, this science has spread across the Globe. It has adapted to a myriad of local conditions and needs of the national health systems with diverse historical legacies, medical services provision, and financing patterns. Challenge of financial sustainability facing modern day health systems remains primarily attributable to population aging, prosperity diseases, large scale migrations, rapid urbanization, and technological innovation in medicine. Despite promising developments in developing countries with emerging BRICS markets on the lead, rising out-of-pocket health spending continues to threaten affordability of medical care. Universal health coverage extension will likely remain serious challenge even for some of the most advanced OECD nations. These complex circumstances create strong drivers for inevitable further development of health economics. We believe that this interdisciplinary health science shall leave long-lasting blue print to be visible for decades to come.

  11. Minimal intervention dentistry: part 1. Strategies for addressing the new caries challenge in older patients.

    PubMed

    Chalmers, Jane M

    2006-06-01

    The aging of the population combined with increased retention of natural teeth into old age means that clinicians now face a new caries challenge in older dentate patients. An increase in the onset of dental caries is evident among patients who may not have had high levels of caries in the past and who may have undergone extensive restorative procedures during their lifetimes. Minimal intervention dentistry (MID), a modern evidence-based approach to caries management in dentate patients, uses the medical model, whereby disease is controlled by the "oral physician" and an affiliated dental team. The main components of a geriatric approach to MID are assessment of the risk of disease, with a focus on early detection and prevention; external and internal remineralization; use of a range of restorations, dental materials and equipment; and surgical intervention only when required and only after disease has been controlled. This first in a series of 2 articles describes and illustrates oral disease management in geriatric MID, which involves the assessment and management of a diverse range of primary and modifying factors, integrated with an evaluation of the plaque-biofilm interface and the resultant dynamic oral disease process.

  12. Paving the road ahead for CD19 CAR T-cell therapy.

    PubMed

    Nellan, Anandani; Lee, Daniel W

    2015-11-01

    Modern immunotherapies, most notably in the form of anti-CD19 chimeric antigen receptor (CAR) T cells, have produced significant clinical responses in otherwise refractory pre-B-cell acute lymphoblastic leukemia patients. Several groups have simultaneously reported robust response rates in children and adults alike. These early studies indicate an impending shift in paradigm for the treatment of acute lymphoblastic leukemia. Incorporating CD19 CAR T-cell therapy into upfront or salvage regimens has its challenges and opportunities. Most CD19 CAR T-cell products in trial today are excellent at inducing minimal residual disease negative remissions, and most responding patients experience cytokine release syndrome and/or neurotoxicity. The challenges facing the CAR community involve how best to minimize the severity of cytokine release syndrome and neurotoxicity while maximizing antitumor efficacy, determining what role this therapy will play for the prophylaxis and treatment of central nervous system leukemia, and its implications on subsequent hematopoietic stem cell transplant given the emergence of CD19-negative relapses. CD19 CAR T-cell therapy is a powerful new tool in the oncologist's arsenal. How it is incorporated into standard practice and how it will shift survival curves are the exciting questions that are waiting to be answered.

  13. Finding Erich Jantsch's Five Crucial Innovations: A Study of Four Small Colleges

    ERIC Educational Resources Information Center

    MacVie, Leah

    2017-01-01

    Institutions of higher education have faced many challenges over the last few decades. Though many large institutions have the resources needed to respond to these challenges, small institutions have had to be innovative in the ways in which they are adapting. There are similarities between the external challenges that institutions face today and…

  14. The Challenges Faced by Chinese Higher Education as It Expands in Scale

    ERIC Educational Resources Information Center

    Xiaohao, Ding

    2004-01-01

    This article reports the challenges faced by Chinese higher education as it expands in scale. The scale of China's higher education has seen unprecedented expansion in recent years. This article explores the new opportunities and challenges that such expansion brings to China's higher education. The author states that, aside from the many…

  15. Reflecting on the Challenges of Applied Theatre in Kenya

    ERIC Educational Resources Information Center

    Okuto, Maxwel; Smith, Bobby

    2017-01-01

    In this article the authors draw on their own experience and research in applied theatre in Kenya in order to reflect on challenges currently facing practitioners working in the country. In order to outline the range of challenges faced by practitioners, issues related to the wider landscapes of government and politics in Kenya are explored,…

  16. Special Education in Rural Schools: Why Less Takes More

    ERIC Educational Resources Information Center

    Bouck, Emily C.; Albaugh, Diane; Bouck, Mary K.

    2005-01-01

    Everyone can understand the challenges teachers face in organizing and supervising field trips, challenges that are even greater when the students have special needs and live in poverty. But how daunting, the authors ask, are the challenges these students face every day? Very few people who have never tried it are truly aware of all the…

  17. International Graduate Students' Academic Writing Practices in Malaysia: Challenges and Solutions

    ERIC Educational Resources Information Center

    Singh, Manjet Kaur Mehar

    2015-01-01

    This article focuses on the challenges faced by non-native English speaking international graduate students in their academic writing practices while they studied at a university in Malaysia as well as the solutions they employed when faced with the challenges. Academic Literacies Questionnaire was used to collect data. Based on 131 participants,…

  18. A Content Analysis Concerning the Studies on Challenges Faced by Novice Teachers

    ERIC Educational Resources Information Center

    Kozikoglu, Ishak

    2017-01-01

    The purpose of this research is to analyze the studies concerning challenges faced by novice teachers in terms of various aspects and compare challenges according to location of the studies conducted in Turkey and abroad. A total of 30 research studies were included in detailed analysis. This is a descriptive study based on qualitative research…

  19. Mentoring Matters: The Challenge for Teacher Education

    ERIC Educational Resources Information Center

    McCann, Thomas M.; Ed.; Johannessen, Larry, Ed.

    2009-01-01

    Beginning teachers face many challenges and difficulties; as a result, one-third will leave the profession in the first three years and nearly half will be gone within their first five years in the profession. The challenge facing university teacher education programs is to fix the hole in the bottom of the bucket and find strategic new ways to…

  20. Radiation Testing, Characterization and Qualification Challenges for Modern Microelectronics and Photonics Devices and Technologies

    NASA Technical Reports Server (NTRS)

    LaBel, Kenneth A.; Cohn, Lewis M.

    2008-01-01

    At an earlier conference we discussed a selection of the challenges for radiation testing of modern semiconductor devices focusing on state-of-the-art CMOS technologies. In this presentation, we extend this discussion focusing on the following areas: (1) Device packaging, (2) Evolving physical single even upset mechanisms, (3) Device complexity, and (4) the goal of understanding the limitations and interpretation of radiation testing results.

  1. Defining the challenges of the Modern Analytical Laboratory (CPSA USA 2014): the risks and reality of personalized healthcare.

    PubMed

    Weng, Naidong; Needham, Shane; Lee, Mike

    2015-01-01

    The 17th Annual Symposium on Clinical and Pharmaceutical Solutions through Analysis (CPSA) 29 September-2 October 2014, was held at the Sheraton Bucks County Hotel, Langhorne, PA, USA. The CPSA USA 2014 brought the various analytical fields defining the challenges of the modern analytical laboratory. Ongoing discussions focused on the future application of bioanalysis and other disciplines to support investigational new drugs (INDs) and new drug application (NDA) submissions, clinical diagnostics and pathology laboratory personnel that support patient sample analysis, and the clinical researchers that provide insights into new biomarkers within the context of the modern laboratory and personalized medicine.

  2. Modernizing Evolutionary Anthropology : Introduction to the Special Issue.

    PubMed

    Mattison, Siobhán M; Sear, Rebecca

    2016-12-01

    Evolutionary anthropology has traditionally focused on the study of small-scale, largely self-sufficient societies. The increasing rarity of these societies underscores the importance of such research yet also suggests the need to understand the processes by which such societies are being lost-what we call "modernization"-and the effects of these processes on human behavior and biology. In this article, we discuss recent efforts by evolutionary anthropologists to incorporate modernization into their research and the challenges and rewards that follow. Advantages include that these studies allow for explicit testing of hypotheses that explore how behavior and biology change in conjunction with changes in social, economic, and ecological factors. In addition, modernization often provides a source of "natural experiments" since it may proceed in a piecemeal fashion through a population. Challenges arise, however, in association with reduced variability in fitness proxies such as fertility, and with the increasing use of relatively novel methodologies in evolutionary anthropology, such as the analysis of secondary data. Confronting these challenges will require careful consideration but will lead to an improved understanding of humanity. We conclude that the study of modernization offers the prospect of developing a richer evolutionary anthropology, by encompassing ultimate and proximate explanations for behavior expressed across the full range of human societies.

  3. New Ethical Challenges within Environmental and Sustainability Education: A Response

    ERIC Educational Resources Information Center

    Todd, Sharon

    2016-01-01

    One of the major points to grow out of the four papers presented in this issue is how to think of education in relation to the various challenges facing the biosphere, facing the future of human and other than human life forms, and facing the sheer difficulties of planning what to do about them. The differences in the role of education, of course,…

  4. Learning about light and optics in on-line general education classes using at-home experimentation

    NASA Astrophysics Data System (ADS)

    Millspaw, Jacob; Wang, Gang; Masters, Mark F.

    2014-07-01

    College students are facing a constantly evolving educational system. Some still see mostly the traditional face to face lecture type classes where as others may never set foot on campus thanks to distance learning programs. In between they may enroll in a mix of face-to-face, two-way broadcasted interactive courses, streaming lecture courses, hybrid face-to-face/ on-line courses and the ominous MOOC! A large number of these non-traditional courses are general education courses and play an important role in developing non-science majors' understanding of science in general, and of physics in particular. We have been keeping pace with theses modern modes of instruction by offering several on-line courses such as Physics for Computer Graphics and Animation and Light and Color. These courses cover basic concepts in light, color and optics.

  5. Performance and accountability : challenges facing the Department of Transportation

    DOT National Transportation Integrated Search

    2001-02-14

    For surface transportation safety, DOT continues to face challenges in improving the safety of highways and pipelines. While the Department of Transportation appears to be making progress on some initiatives to reduce the number of large truck crashe...

  6. Toward a Social Psychophysics of Face Communication.

    PubMed

    Jack, Rachael E; Schyns, Philippe G

    2017-01-03

    As a highly social species, humans are equipped with a powerful tool for social communication-the face. Although seemingly simple, the human face can elicit multiple social perceptions due to the rich variations of its movements, morphology, and complexion. Consequently, identifying precisely what face information elicits different social perceptions is a complex empirical challenge that has largely remained beyond the reach of traditional methods. In the past decade, the emerging field of social psychophysics has developed new methods to address this challenge, with the potential to transfer psychophysical laws of social perception to the digital economy via avatars and social robots. At this exciting juncture, it is timely to review these new methodological developments. In this article, we introduce and review the foundational methodological developments of social psychophysics, present work done in the past decade that has advanced understanding of the face as a tool for social communication, and discuss the major challenges that lie ahead.

  7. Conversion of HSPF Legacy Model to a Platform-Independent, Open-Source Language

    NASA Astrophysics Data System (ADS)

    Heaphy, R. T.; Burke, M. P.; Love, J. T.

    2015-12-01

    Since its initial development over 30 years ago, the Hydrologic Simulation Program - FORTAN (HSPF) model has been used worldwide to support water quality planning and management. In the United States, HSPF receives widespread endorsement as a regulatory tool at all levels of government and is a core component of the EPA's Better Assessment Science Integrating Point and Nonpoint Sources (BASINS) system, which was developed to support nationwide Total Maximum Daily Load (TMDL) analysis. However, the model's legacy code and data management systems have limitations in their ability to integrate with modern software, hardware, and leverage parallel computing, which have left voids in optimization, pre-, and post-processing tools. Advances in technology and our scientific understanding of environmental processes that have occurred over the last 30 years mandate that upgrades be made to HSPF to allow it to evolve and continue to be a premiere tool for water resource planners. This work aims to mitigate the challenges currently facing HSPF through two primary tasks: (1) convert code to a modern widely accepted, open-source, high-performance computing (hpc) code; and (2) convert model input and output files to modern widely accepted, open-source, data model, library, and binary file format. Python was chosen as the new language for the code conversion. It is an interpreted, object-oriented, hpc code with dynamic semantics that has become one of the most popular open-source languages. While python code execution can be slow compared to compiled, statically typed programming languages, such as C and FORTRAN, the integration of Numba (a just-in-time specializing compiler) has allowed this challenge to be overcome. For the legacy model data management conversion, HDF5 was chosen to store the model input and output. The code conversion for HSPF's hydrologic and hydraulic modules has been completed. The converted code has been tested against HSPF's suite of "test" runs and shown good agreement and similar execution times while using the Numba compiler. Continued verification of the accuracy of the converted code against more complex legacy applications and improvement upon execution times by incorporating an intelligent network change detection tool is currently underway, and preliminary results will be presented.

  8. Flow and Grit by Design: Exploring Gamification in Facilitating Adherence to Swallowing Therapy.

    PubMed

    Constantinescu, Gabriela; Rieger, Jana; Mummery, Kerry; Hodgetts, William

    2017-11-08

    Delivery of swallowing therapy is faced with challenges regarding access to in-clinic services and adherence to prescribed home programs. Mobile health (mHealth) technologies are being developed at a rapid pace to address these difficulties. Whereas some benefits to using these modern tools for therapy are obvious (e.g., electronic reminders), other advantages are not as well understood. One example is the potential for mHealth devices and apps to enhance adherence to treatment regimens. This article introduces a number of psychological concepts that relate to adherence and that can be leveraged by mHealth. Elements that contribute to flow (optimal experience) during an activity and those that reinforce grit (perseverance to achieve a long-term goal) can be used to engage patients in their own rehabilitation. The experience of flow can be targeted by presenting the rehabilitation exercise as an optimally challenging game, one that offers a match between challenge and ability. Grit can be supported by reinforcing routine and by varying the therapy experience using different games. A combination of hardware and software design approaches have the potential to transform uninteresting and repetitive activities, such as those that make up swallowing therapy regimens, into engaging ones. The field of gamification, however, is still developing, and gamified mHealth apps will need to withstand scientific testing of their claims and demonstrate effectiveness in all phases of outcome research.

  9. Quantitative analysis of glycerophospholipids by LC-MS: acquisition, data handling, and interpretation

    PubMed Central

    Myers, David S.; Ivanova, Pavlina T.; Milne, Stephen B.; Brown, H. Alex

    2012-01-01

    As technology expands what it is possible to accurately measure, so too the challenges faced by modern mass spectrometry applications expand. A high level of accuracy in lipid quantitation across thousands of chemical species simultaneously is demanded. While relative changes in lipid amounts with varying conditions may provide initial insights or point to novel targets, there are many questions that require determination of lipid analyte absolute quantitation. Glycerophospholipids present a significant challenge in this regard, given the headgroup diversity, large number of possible acyl chain combinations, and vast range of ionization efficiency of species. Lipidomic output is being used more often not just for profiling of the masses of species, but also for highly-targeted flux-based measurements which put additional burdens on the quantitation pipeline. These first two challenges bring into sharp focus the need for a robust lipidomics workflow including deisotoping, differentiation from background noise, use of multiple internal standards per lipid class, and the use of a scriptable environment in order to create maximum user flexibility and maintain metadata on the parameters of the data analysis as it occurs. As lipidomics technology develops and delivers more output on a larger number of analytes, so must the sophistication of statistical post-processing also continue to advance. High-dimensional data analysis methods involving clustering, lipid pathway analysis, and false discovery rate limitation are becoming standard practices in a maturing field. PMID:21683157

  10. Inference of ecological and social drivers of human brain-size evolution.

    PubMed

    González-Forero, Mauricio; Gardner, Andy

    2018-05-01

    The human brain is unusually large. It has tripled in size from Australopithecines to modern humans 1 and has become almost six times larger than expected for a placental mammal of human size 2 . Brains incur high metabolic costs 3 and accordingly a long-standing question is why the large human brain has evolved 4 . The leading hypotheses propose benefits of improved cognition for overcoming ecological 5-7 , social 8-10 or cultural 11-14 challenges. However, these hypotheses are typically assessed using correlative analyses, and establishing causes for brain-size evolution remains difficult 15,16 . Here we introduce a metabolic approach that enables causal assessment of social hypotheses for brain-size evolution. Our approach yields quantitative predictions for brain and body size from formalized social hypotheses given empirical estimates of the metabolic costs of the brain. Our model predicts the evolution of adult Homo sapiens-sized brains and bodies when individuals face a combination of 60% ecological, 30% cooperative and 10% between-group competitive challenges, and suggests that between-individual competition has been unimportant for driving human brain-size evolution. Moreover, our model indicates that brain expansion in Homo was driven by ecological rather than social challenges, and was perhaps strongly promoted by culture. Our metabolic approach thus enables causal assessments that refine, refute and unify hypotheses of brain-size evolution.

  11. LARP Long Quadrupole: A "Long" Step Toward an LHC

    ScienceCinema

    Giorgio Ambrosio

    2017-12-09

    The beginning of the development of Nb3Sn magnets for particle accelerators goes back to the 1960’s. But only very recently has this development begun to face the challenges of fabricating Nb3Sn magnets which can meet the requirements of modern particle accelerators. LARP (the LHC Accelerator Research Program) is leading this effort focusing on long models of the Interaction Region quadrupoles for a possible luminosity upgrade of the Large Hadron Collider. A major milestone in this development is to test, by the end of 2009, 4m-long quadrupole models, which will be the first Nb3Sn accelerator-type magnets approaching the length of real accelerator magnets. The Long Quadrupoles (LQ) are “Proof-of-Principle” magnets which are to demonstrate that Nb3Sn technology is sufficiently mature for use in high energy particle accelerators. Their design is based on the LARP Technological Quadrupole (TQ) models, under development at FNAL and LBNL, which have design gradients higher than 200 T/m and an aperture of 90 mm. Several challenges must be addressed for the successful fabrication of long Nb3Sn coils and magnets. These challenges and the solutions adopted will be presented together with the main features of the LQ magnets. Several R&D lines are participating to this effort and their contributions will be also presented.

  12. Pose-Invariant Face Recognition via RGB-D Images.

    PubMed

    Sang, Gaoli; Li, Jing; Zhao, Qijun

    2016-01-01

    Three-dimensional (3D) face models can intrinsically handle large pose face recognition problem. In this paper, we propose a novel pose-invariant face recognition method via RGB-D images. By employing depth, our method is able to handle self-occlusion and deformation, both of which are challenging problems in two-dimensional (2D) face recognition. Texture images in the gallery can be rendered to the same view as the probe via depth. Meanwhile, depth is also used for similarity measure via frontalization and symmetric filling. Finally, both texture and depth contribute to the final identity estimation. Experiments on Bosphorus, CurtinFaces, Eurecom, and Kiwi databases demonstrate that the additional depth information has improved the performance of face recognition with large pose variations and under even more challenging conditions.

  13. Facilitating the High School-to-College Transition for Students with Psychiatric Disabilities: Information and Strategies for School Counselors

    ERIC Educational Resources Information Center

    Fier, Sara M.; Brzezinski, Lynda G.

    2010-01-01

    The transition from high school to college is challenging for many students. In addition to the typical challenges faced by students starting college, students with previously diagnosed psychiatric disabilities have illness-related challenges to face as they transition to college. This article provides information on the current state of concerns…

  14. College Students with High-Functioning Autism Spectrum Disorder: Best Practices for Successful Transition to the World of Work

    ERIC Educational Resources Information Center

    Dipeolu, Abiola O.; Storlie, Cassandra; Johnson, Carol

    2015-01-01

    The transition from college to work is a challenging time for students with autism spectrum disorder. College counselors who understand the challenges students face adjusting to the world of work can position themselves to be change agents for this population. This article illuminates the challenges facing these students to help close the…

  15. Challenges Faced by Pre-Service Chemistry Teachers Teaching in a Laboratory and Their Solution Proposals

    ERIC Educational Resources Information Center

    Yalcin-Celik, Ayse; Kadayifci, Hakki; Uner, Sinem; Turan-Oluk, Nurcan

    2017-01-01

    This study examines the challenges faced by pre-service chemistry teachers teaching in a laboratory and their proposed solutions to these challenges. The study was conducted in a 13-week-long methodology course. Written statements from participants and observations from researchers were used as data sources. From these data, it was found that the…

  16. Investigation of the Challenges, Mentoring Needs, and Support for Business and Marketing Teachers

    ERIC Educational Resources Information Center

    Yohon, Teresa

    2005-01-01

    The purpose of this study was to determine the challenges that new business/marketing teachers face as well as the current support structures available to them and to determine experienced business/marketing teachers perceptions of the challenges faced by new teachers as well as the types of support that they were willing to provide to new…

  17. Challenges Faced by a Faith-Based School in a Rural, Predominantly Secular Setting: Implications

    ERIC Educational Resources Information Center

    Evangelinou-Yiannakis, Angela

    2016-01-01

    A new, independent Catholic school in rural Australia has had to face significant challenges in relation to its distinct Catholic ethos and curriculum. The challenges have included resistance from parents of the School with regard to the weekly time allocation for Religious Education, the nature of the faith-based curriculum, and the way in which…

  18. Challenges for nurses who work in community mental health centres in the West Bank, Palestine.

    PubMed

    Marie, Mohammad; Hannigan, Ben; Jones, Aled

    2017-01-01

    Nurses in Palestine (occupied Palestinian territory) work in a significantly challenging environment. The mental health care system is underdeveloped and under-resourced. For example, the total number of nurses who work in community mental health centres in the West Bank is seventeen, clearly insufficient in a total population of approximately three million. This research explored daily challenges that Palestinian community mental health nurses (CMHNs) face within and outside their demanding workplaces. An interpretive qualitative design was chosen. Face-to-face interviews were completed with fifteen participants. Thirty-two hours of observations of the day-to-day working environment and workplace routines were conducted in two communities' mental health centres. Written documents relating to practical job-related policies were also collected from various workplaces. Thematic analysis was used across all data sources resulting in four main themes, which describe the challenges faced by CMHNs. These themes consist of the context of unrest, stigma, lack of resources, and organisational or mental health system challenges. The study concludes with a better understanding of challenges in nursing which draws on wider cultural contexts and resilience. The outcomes from this study can be used to decrease the challenges for health professionals and enhance the mental health care system in Palestine.

  19. 2007 Combat Vehicles Conference - Today’s Challenges: Fighting, Sustaining, Modernizing and Transforming

    DTIC Science & Technology

    2007-10-24

    Programs) 1 . FCS MULE .wmv format 2. FCS NLOS Crate Of Fire .wmv format 3. FCS Robotic Convoy .wmv format 4. FCS...included in these sessions will be two “back by popular demand” highlights from previous conferences: 1 ) an update on combat operations in iraq from...15 am - 11:30 am general session general sessiOn - sessiOn 1 : “today’s challenges: fighting, sustaining, modernizing and transforming

  20. Systems Engineering Building Advances Power Grid Research

    ScienceCinema

    Virden, Jud; Huang, Henry; Skare, Paul; Dagle, Jeff; Imhoff, Carl; Stoustrup, Jakob; Melton, Ron; Stiles, Dennis; Pratt, Rob

    2018-01-16

    Researchers and industry are now better equipped to tackle the nation’s most pressing energy challenges through PNNL’s new Systems Engineering Building – including challenges in grid modernization, buildings efficiency and renewable energy integration. This lab links real-time grid data, software platforms, specialized laboratories and advanced computing resources for the design and demonstration of new tools to modernize the grid and increase buildings energy efficiency.

  1. Contextual view including south (rear) of building 925, exercise in ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Contextual view including south (rear) of building 925, exercise in foreground, and modern buildings in background. Facing northwest. - Travis Air Force Base, Building No. 925, W Street, Fairfield, Solano County, CA

  2. You're the Business--A Custom-Made Business Challenge for Modern Languages Students

    ERIC Educational Resources Information Center

    Penet, Jean-Christophe

    2016-01-01

    Modern Languages (ML) students often express concerns about their perceived lack of commercial awareness, worrying that this will put them at a disadvantage, compared with business graduates for instance, when applying for jobs. To try and change this perception, Newcastle University's School of Modern Languages (SML) teamed up with the Careers…

  3. The Sacred or the Profane: The Challenge of Modern Dance in Religious Educational Settings

    ERIC Educational Resources Information Center

    Clement, Karen

    2008-01-01

    The article addresses the utilization of modern dance compositional approaches in the development of sacred dance works. A brief history of sacred dance in the Western Church is traced as a foundation for students' stereotypical approaches to dance and religion. Also examined is the 20th Century modern dance choreographers' practice of…

  4. Innovative Teaching Practice: Traditional and Alternative Methods (Challenges and Implications)

    ERIC Educational Resources Information Center

    Nurutdinova, Aida R.; Perchatkina, Veronika G.; Zinatullina, Liliya M.; Zubkova, Guzel I.; Galeeva, Farida T.

    2016-01-01

    The relevance of the present issue is caused be the strong need in alternative methods of learning foreign language and the need in language training and retraining for the modern professionals. The aim of the article is to identify the basic techniques and skills in using various modern techniques in the context of modern educational tasks. The…

  5. Delayed Fertility Transition among Indigenous Women: A Case Study in the Ecuadoran Amazon

    PubMed Central

    Davis, Jason; Gray, Clark; Bilsborrow, Richard

    2015-01-01

    CONTEXT Communities indigenous to the Amazon are among the few remaining worldwide still practicing near natural fertility, without the use of modern contraceptives. Given the large proportion of women desiring no more births, information on the challenges women there face in limiting fertility would be useful. METHODS Samples of women of reproductive age from five indigenous ethnic groups in the Northern Ecuadorian Amazon were surveyed in 2001 and 2012. Cross-sectional and longitudinal analyses examined married women’s desire for another child at both times and modern contraceptive use in 2012, as well as determinants of a change in women’s desire to have more children and of the number of children born during the study period. RESULTS In 2001, 48% of married women desired another child, 2% used a modern contraceptive and 50% had an unmet need for limiting; in 2012, the proportions were 40%, 19% and 47%, respectively. The total fertility rate was 7.9 in 2001 and 7.0 in 2012. Characteristics associated with wanting another child in 2001 and 2012 included parity (odds ratios, 0.6 and 0.4, respectively) and experience of a child death (2.0 each); characteristics associated with contraceptive use in 2012 included desire for another child, experience of a child death and presence of a community health worker (0.3–0.5). Number of children born was positively associated, and the square of the term negatively associated, with no longer wanting more children in 2012 among women who wanted more in 2001 (odds ratios, 2.1 and 0.9, respectively). CONCLUSIONS Indigenous women in the Northern Ecuadorian Amazon appear to be transitioning to lower fertility. Insufficient access to credible information about the safety and efficacy of modern contraceptives, however, may slow the transition. International Perspectives on Sexual and Reproductive Health, 2015, 41(1):TK. PMID:25856232

  6. A paradigm shift to enable more cost-effective space science telescope missions in the upcoming decades

    NASA Astrophysics Data System (ADS)

    Matthews, Gary; Havey, Keith, Jr.; Egerman, Robert

    2010-07-01

    Modern astronomy currently is dealing with an exciting but challenging dichotomy. On one hand, there has been and will continue to be countless advances in scientific discovery, but on the other the astronomical community is faced with what unfortunately is considered by many to be an insurmountable budgetary impasse for the foreseeable future. The National Academy of Sciences' Astro2010: Decadal Survey has been faced with the difficult challenge of prioritizing sciences and missions for the upcoming decade while still allowing room for new, yet to be discovered opportunities to receive funding. To this end, we propose the consideration of a paradigm shift to the astronomical community that may enable more cost efficient space-based telescope missions to be funded and still provide a high science return per dollar invested. The proposed paradigm shift has several aspects that make it worthy of consideration: 1) Telescopes would leverage existing Commercial Remote Sensing Satellite (CRSS) Architectures such as the 1.1m NextView systems developed by ITT, GeoEye-1, and WorldView-2, or the 0.7m IKONOS system (or perhaps other proprietary systems); 2) By using large EELV class fairings, multiple telescopes with different science missions could be flown on a single spacecraft bus sharing common features such as communications and telemetry (current Earth Science missions in early development phases are considering this approach); 3) Multiple smaller observatories (with multiple spacecraft) could be flown in a single launch vehicle for instances where the different science payloads had incompatible requirements; and 4) by leveraging CRSS architectures, vendors could supply telescopes at a fixed price. Here we discuss the implications and risks that the proposed paradigm shift would carry.

  7. A novel organizational model to face the challenge of multimorbid elderly patients in an internal medicine setting: a case study from Parma Hospital, Italy.

    PubMed

    Meschi, Tiziana; Ticinesi, Andrea; Prati, Beatrice; Montali, Arianna; Ventura, Antonio; Nouvenne, Antonio; Borghi, Loris

    2016-08-01

    Continuous increase of elderly patients with multimorbidity and Emergency Department (ED) overcrowding are great challenges for modern medicine. Traditional hospital organizations are often too rigid to solve them without consistently rising healthcare costs. In this paper we present a new organizational model achieved at Internal Medicine and Critical Subacute Care Unit of Parma University Hospital, Italy, a 106-bed internal medicine area organized by intensity of care and specifically dedicated to such patients. The unit is partitioned into smaller wards, each with a specific intensity level of care, including a rapid-turnover ward (mean length of stay <4 days) admitting acutely ill patients from the ED, a subacute care ward for chronic critically ill subjects and a nurse-managed ward for stable patients who have socio-economic trouble preventing discharge. A very-rapid-turnover ("come'n'go") ward has also been instituted to manage sudden ED overflows. Continuity, effectiveness, safety and appropriateness of care are guaranteed by an innovative figure called "flow manager," with skilled clinical experience and managerial attitude, and by elaboration of an early personalized discharge plan anticipating every patient's needs according to lean methodology principles. In 2012-2014, this organizational model, compared with other peer units of the hospital and of other teaching hospitals of the region, showed a better performance, efficacy and effectiveness indexes calculated on Regional Hospital Discharge Records database system, allowing a capacity to face a massive (+22 %) rise in medical admissions from the ED. Further studies are needed to validate this model from a patient outcome point of view.

  8. Federal Aviation Administration : challenges in modernizing the agency

    DOT National Transportation Integrated Search

    2000-02-01

    FAA's efforts to implement initiatives in five key areas-air traffic control modernization, procurement and personnel reform, aviation safety, aviation and computer security, and financial management-have met with limited success. For example, FAA ha...

  9. Examining the Roles of the Facilitator in Online and Face-to-Face PD Contexts

    ERIC Educational Resources Information Center

    Park, Gina; Johnson, Heather; Vath, Richard; Kubitskey, Beth; Fishman, Barry

    2013-01-01

    Online teacher professional development has become an alternative to face-to-face professional development. Such a shift from face-to-face to online professional development, however, brings new challenges for professional development facilitators, whose roles are crucial in orchestrating teacher learning. This paper is motivated by the need to…

  10. Assessing the impact of Hurricanes Irene and Sandy on the morphology and modern sediment thickness on the inner continental shelf offshore of Fire Island, New York

    USGS Publications Warehouse

    Schwab, William C.; Baldwin, Wayne E.; Denny, Jane F.

    2016-01-15

    This report documents the changes in seabed morphology and modern sediment thickness detected on the inner continental shelf offshore of Fire Island, New York, before and after Hurricanes Irene and Sandy made landfall. Comparison of acoustic backscatter imagery, seismic-reflection profiles, and bathymetry collected in 2011 and in 2014 show that sedimentary structures and depositional patterns moved alongshore to the southwest in water depths up to 30 meters during the 3-year period. The measured lateral offset distances range between about 1 and 450 meters with a mean of 20 meters. The mean distances computed indicate that change tended to decrease with increasing water depth. Comparison of isopach maps of modern sediment thickness show that a series of shoreface-attached sand ridges, which are the dominant sedimentary structures offshore of Fire Island, migrated toward the southwest because of erosion of the ridge crests and northeast-facing flanks as well as deposition on the southwest-facing flanks and in troughs between individual ridges. Statistics computed suggest that the modern sediment volume across the about 81 square kilometers of common sea floor mapped in both surveys decreased by 2.8 million cubic meters, which is a mean change of –0.03 meters, which is smaller than the resolution limit of the mapping systems used.

  11. Challenges and strategies for coping with scleroderma: implications for a scleroderma-specific self-management program.

    PubMed

    Milette, Katherine; Thombs, Brett D; Maiorino, Kristina; Nielson, Warren R; Körner, Annett; Peláez, Sandra

    2018-05-09

    The purpose of this study was to explore challenges faced by patients with systemic sclerosis, also called scleroderma, in coping with their disease and the strategies they used to face those challenges. Five focus groups were held with scleroderma patients (4 groups, n = 34) and health care professionals who have experience treating scleroderma (1 group, n = 8). Participants' discussions were recorded, transcribed and analyzed using thematic analysis. Participants reported challenges accessing information (e.g., knowledgeable specialists), dealing with negative emotions (e.g., stress due to misunderstandings with loved ones), and accessing resources (e.g., helpful products or devices). Strategies for overcoming challenges were also discussed (e.g., advocating for own needs). When faced with significant challenges while coping with scleroderma, patients develop strategies to manage better and improve their quality of life. To help them cope, patients would benefit from easier access to supportive interventions, including tailored scleroderma self-management programs. Although the challenges experienced by patients with scleroderma are unique, findings from this study might help better understand patients' perspectives regarding coping and disease management for other chronic diseases as well. Implications for Rehabilitation People living with rare diseases, including the rare autoimmune disease scleroderma, face unique challenges and often do not have access to disease-specific educational or other support resources. People with scleroderma report that they face challenges in accessing information, including knowledgeable healthcare providers; managing difficult social interactions and negative emotions; and accessing resources. Strategies employed by scleroderma patients to overcome these challenges include seeking connections to other people with scleroderma or scleroderma patient organizations, actively seeking out local resources, and learning to communicate and advocate more effectively. Rehabilitation professionals can support people with scleroderma by providing them with information on connecting with scleroderma patient organizations or by facilitating local patient support networks.

  12. Challenges newly-arrived migrant women in Montreal face when needing maternity care: Health care professionals' perspectives.

    PubMed

    Peláez, Sandra; Hendricks, Kristin N; Merry, Lisa A; Gagnon, Anita J

    2017-01-25

    People who leave their country of origin, or the country of habitual residence, to establish themselves permanently in another country are usually referred to as migrants. Over half of all births in Montreal, Canada are to migrant women. To understand healthcare professionals' attitudes towards migrants that could influence their delivery of care, our objective was to explore their perspectives of challenges newly-arrived migrant women from non-Western countries face when needing maternity care. In this qualitative multiple case study, we conducted face-to-face interviews with 63 health care professionals from four teaching hospitals in Montreal, known for providing maternity care to a high volume of migrant women. Interviews were transcribed and thematically analysed. Physicians, nurses, social workers, and therapists participated; 90% were female; and 17% were themselves migrants from non-Western countries. According to participants, newly-arrived migrant women face challenges at two levels: (a) direct care (e.g., understanding Canadian health care professionals' expectations, communicating effectively with health care professionals), and (b) organizational (e.g., access to appropriate health care). Challenges women face are strongly influenced by the migrant woman's background as well as social position (e.g., general education, health literacy, socio-cultural integration) and by how health care professionals balance women's needs with perceived requirement to adhere to standard procedures and regulations. Health care professionals across institutions agreed that maternity care-related challenges faced by newly-arrived migrant women often are complex in that they are simultaneously driven by conflicting values: those based on migrant women's sociocultural backgrounds versus those related to the implementation of Canadian guidelines for maternity care in which consideration of migrant women's particular needs are not priority.

  13. Scotland: Education, Curriculum and Learning. the Strengths, Challenges and Solutions in Lifelong Learning. IBE Working Papers on Curriculum Issues No. 13

    ERIC Educational Resources Information Center

    Armstrong, Alan

    2014-01-01

    This paper brings together the main strengths and challenges currently facing Scottish education and outlines approaches to the ways forward. Knowledge about how to improve education systems has grown rapidly over the last two decades. One key challenge facing Scotland, and no doubt many other countries, is in ensuring a smooth "learner…

  14. Threat Control through Arms Control. Report to Congress 1994

    DTIC Science & Technology

    1994-07-13

    reduction, chemical weapons’ elimination, or any of the other growing arms control and nonproliferation challenges America faces, ACDA is an essential...nuclear missile reduction, chemical weapons elimination, or any of. the other growing arms control and nonproliferation challenges America faces... challenging . Nonprolif eration agreements are our first line of defense against the creation of a far more unstable and hazardous world than we have ever

  15. School Supplies on a Budget

    ERIC Educational Resources Information Center

    Dyrli, Kurt O.

    2008-01-01

    This article reports on the challenge that parents, teachers, and district administrators face in continuing to provide essential school supplies to their students despite budget cuts. At the Verona Area (Wisconsin) School District, administrators, teachers, and parents have recently faced this common challenge. Increasingly dependent on funding…

  16. Challenges and Concerns Faced by Doctoral Candidates Seeking Academic Positions.

    ERIC Educational Resources Information Center

    Porter, Dion; Donnell, Chandra; Buck, Tina; Edwards, Yolanda

    A panel discussion offered suggestions and recommendations for faculty and institutions of rehabilitation counseling education on more effective recruitment methods. Strategies were also considered for potential faculty members. Candidates seeking academic positions in rehabilitation counseling education face many challenges. Location of program;…

  17. Lessons Learned From Developing a Sustainable Arsenic-Safe Water Program in West Bengal, India Over a Period of Eight Years

    NASA Astrophysics Data System (ADS)

    Smith, M. M.; Liaw, J.; Hira, A.; Guha, P.; Pal, S. S.; Hore, T.; Smith, A. H.

    2010-12-01

    Arsenic is a carcinogen, and causes many cancers and noncancer diseases. Recent findings have shown that exposure to arsenic in drinking water as a child or before birth can cause illness and death even as an adult. In the West Bengal region of India, more than six million people are drinking crystal clear but arsenic-contaminated water from tubewells. Project Well, a non-profit organization based in California, has provided safe drinking water to villages in West Bengal since 2001 through modern modified dugwells, currently numbering 163. Along the way, Project Well has faced the challenge of persuading people to stop consuming good-tasting, arsenic-laced water and instead drink chlorinated water, which is safe but may have the smell of chlorine. Additionally, West Bengal receives abundant annual rainfall, and hence it is difficult to convince people to pay for treated water. From its inception, the Project Well program was set up with a tracking system to assess the efficacy of the modern dugwells, which has helped identify where technical improvements were needed. Continuous interaction with community-based user groups has also helped overcome many constraints and make the program sustainable. Project Well monitoring records from August 2010 show that out of 163 modern dugwells, 48 percent were being used, providing water for 2948 villagers; 23 percent were closed; 6 percent were dry (11 districts of West Bengal were in a drought); 6 percent required maintenance; and 7 percent were not used. Arsenic concentrations in the modern dugwells were measured every year during peak season when the water table was low and the median arsenic concentration of operational dugwells over the eight years between 2002 and 2010 was 15 ppb (the permissible limit in India is 50 ppb). Each year, about 6 to 10 percent of the dugwells have arsenic levels above 50 ppb during the summer season, when the water level is low. Bacterial counts, i.e., total coliform and fecal coliform, are also measured in newly constructed modern dugwells. Theoline, a chlorine-based disinfectant, is applied weekly at a dose of 4 ounces per 100 gallons of water. There have been no reports of diarrheal diseases related to these modern dugwell water. Some dugwell sites have been very successful, with more than 100 users, and Project Well is now expanding to other districts.

  18. Biogeoscience from a Metallomic and Proteomic Perspective

    NASA Astrophysics Data System (ADS)

    Anbar, A. D.; Shock, E.

    2004-12-01

    In the wake of the genomics revolution, life scientists are expanding their focus from the genome to the "proteome" - the assemblage of all proteins in a cell - and the "metallome" - the distribution of inorganic species in a cell. The proteome and metallome are tightly connected because proteins and protein products are intimately involved in the transport and homeostasis of inorganic elements, and because many enzymes depend on inorganic elements for catalytic activity. Together, they are at the heart of metabolic function. Unlike the relatively static genome, the proteome and metallome are extremely dynamic, changing rapidly in response to environmental cues. They are substantially more complex than the genome; for example, in humans, some 30,000 genes code for approximately 500,000 proteins. Metaphorically, the proteome and metallome constitute the complex, dynamic "language" by which the genome and the environment communicate. Therefore biogeochemists, like life scientists, are moving beyond a strictly genomic perspective. Research guided by proteomic and metallomic perspectives and methodologies should provide new insights into the connections between life and the inorganic Earth in modern environments, and the evolution of these connections through time. For example, biogeochemical research in modern environments, such as Yellowstone hot springs, is hindered by the gap between genomic determinations of metabolic potential in ecosystems and geochemical characterizations of the energetic boundary conditions faced by these ecosystems; genomics tells us "who is there" and geochemistry tells us "what they might be doing", but neither genomics nor geochemistry easily provide quantitative information about which metabolisms are actually active or a framework for understanding why ecosystems do not fully exploit the energy available in their surroundings. Such questions are fundamentally kinetic rather than thermodynamic and therefore demand that we characterize and understand the proteins and inorganic elements used by organisms to catalyze reactions and capture energy from their surroundings. Similar challenges are faced when attempting to map the evolutionary relationships inferred from phylogenetic analyses of genomes to ecological histories determined by geochemists and paleobiologists - for example, ongoing efforts to understand the evolutionary history of eukaryotes and metazoa - because the driving forces for the evolution and ecological radiation of organisms lie at the intersection of metabolism and environment, and hence in the gap between genomes and geochemistry. Future progress in understanding the biogeochemistry of modern and ancient environments will be spurred by integrating proteomic and metallomic methods and perspectives.

  19. Thesis: Do we face a third revolution in human history? If so, how will public health respond?

    PubMed

    Hanlon, Phil; Carlisle, Sandra

    2008-12-01

    A range of evidence suggests that the dominant culture associated with the economic systems of 'modern' societies has become a major source of pressure on global resources and may precipitate a third revolution in human history, with major implications for health and well-being. This paper aims to consider whether there are historical analogies with contemporary circumstances which might help us make connections between past and present predicaments in the human condition; to highlight the underpinnings of such predicaments in the politico-economic and cultural systems found in 'modern' societies; to outline questions prompted by this analysis, and stimulate greater debate around the issues raised. We draw on evidence and arguments condensed from complex research and theorizing from multiple disciplines. Contemporary evidence suggests that global depletion of a key energy resource (oil), increasing environmental degradation and imminent climate change can be linked to human socio-economic and cultural systems which are now out of balance with their environment. Those systems are associated with Western-type societies, where political philosophies of neo-liberalism, together with cultural values of individualism, materialism and consumerism, support an increasingly globalized capitalist economic system. Evidence points to a decline of psychological and social well-being in such societies. We need to work out how to prevent/ameliorate the harms likely to flow from climate change and rising oil costs. Public health professionals face the challenge of preventing adverse health consequences likely to result from continued adherence to the have-it-all mindset prevailing in contemporary Western societies. Equally, we need to seek out the potential health dividends that could be realized in terms of reduced obesity, improved well-being and greater social equity, while not under-estimating the likelihood of profound resistance, from many sectors of society, to unwanted but inevitable change.

  20. Herbal traditional Chinese medicine and its evidence base in gastrointestinal disorders

    PubMed Central

    Teschke, Rolf; Wolff, Albrecht; Frenzel, Christian; Eickhoff, Axel; Schulze, Johannes

    2015-01-01

    Herbal traditional Chinese medicine (TCM) is used to treat several ailments, but its efficiency is poorly documented and hence debated, as opposed to modern medicine commonly providing effective therapies. The aim of this review article is to present a practical reference guide on the role of herbal TCM in managing gastrointestinal disorders, supported by systematic reviews and evidence based trials. A literature search using herbal TCM combined with terms for gastrointestinal disorders in PubMed and the Cochrane database identified publications of herbal TCM trials. Results were analyzed for study type, inclusion criteria, and outcome parameters. Quality of placebo controlled, randomized, double-blind clinical trials was poor, mostly neglecting stringent evidence based diagnostic and therapeutic criteria. Accordingly, appropriate Cochrane reviews and meta-analyses were limited and failed to support valid, clinically relevant evidence based efficiency of herbal TCM in gastrointestinal diseases, including gastroesophageal reflux disease, gastric or duodenal ulcer, dyspepsia, irritable bowel syndrome, ulcerative colitis, and Crohn’s disease. In conclusion, the use of herbal TCM to treat various diseases has an interesting philosophical background with a long history, but it received increasing skepticism due to the lack of evidence based efficiency as shown by high quality trials; this has now been summarized for gastrointestinal disorders, with TCM not recommended for most gastrointestinal diseases. Future studies should focus on placebo controlled, randomized, double-blind clinical trials, herbal product quality and standard criteria for diagnosis, treatment, outcome, and assessment of adverse herb reactions. This approach will provide figures of risk/benefit profiles that hopefully are positive for at least some treatment modalities of herbal TCM. Proponents of modern herbal TCM best face these promising challenges of pragmatic modern medicine by bridging the gap between the two medicinal cultures. PMID:25914456

  1. Herbal traditional Chinese medicine and its evidence base in gastrointestinal disorders.

    PubMed

    Teschke, Rolf; Wolff, Albrecht; Frenzel, Christian; Eickhoff, Axel; Schulze, Johannes

    2015-04-21

    Herbal traditional Chinese medicine (TCM) is used to treat several ailments, but its efficiency is poorly documented and hence debated, as opposed to modern medicine commonly providing effective therapies. The aim of this review article is to present a practical reference guide on the role of herbal TCM in managing gastrointestinal disorders, supported by systematic reviews and evidence based trials. A literature search using herbal TCM combined with terms for gastrointestinal disorders in PubMed and the Cochrane database identified publications of herbal TCM trials. Results were analyzed for study type, inclusion criteria, and outcome parameters. Quality of placebo controlled, randomized, double-blind clinical trials was poor, mostly neglecting stringent evidence based diagnostic and therapeutic criteria. Accordingly, appropriate Cochrane reviews and meta-analyses were limited and failed to support valid, clinically relevant evidence based efficiency of herbal TCM in gastrointestinal diseases, including gastroesophageal reflux disease, gastric or duodenal ulcer, dyspepsia, irritable bowel syndrome, ulcerative colitis, and Crohn's disease. In conclusion, the use of herbal TCM to treat various diseases has an interesting philosophical background with a long history, but it received increasing skepticism due to the lack of evidence based efficiency as shown by high quality trials; this has now been summarized for gastrointestinal disorders, with TCM not recommended for most gastrointestinal diseases. Future studies should focus on placebo controlled, randomized, double-blind clinical trials, herbal product quality and standard criteria for diagnosis, treatment, outcome, and assessment of adverse herb reactions. This approach will provide figures of risk/benefit profiles that hopefully are positive for at least some treatment modalities of herbal TCM. Proponents of modern herbal TCM best face these promising challenges of pragmatic modern medicine by bridging the gap between the two medicinal cultures.

  2. Using International Classification of Functioning, Disability and Health to understand challenges in community reintegration of injured veterans.

    PubMed

    Resnik, Linda J; Allen, Susan M

    2007-01-01

    This pilot study used the framework of the World Health Organization's International Classification of Functioning, Disability and Health (ICF) to understand the challenges faced by Operation Enduring Freedom (OEF) and Operation Iraqi Freedom (OIF) veterans as they reintegrate into the community. We conducted semistructured interviews with 14 injured veterans, 12 caregivers, and 14 clinicians. We used ICF taxonomy to code data and identify issues. We identified challenges in the following ICF domains: learning and applying knowledge; general tasks and demands; communication; mobility; self-care; domestic life; interpersonal interactions, major life areas; and community, social, and civic life. We found many similarities between the challenges faced by veterans with and without polytraumatic injuries, although veterans with polytraumatic injuries faced challenges of greater magnitude. Identifying community reintegration challenges early and promoting reintegration are important mandates for the Department of Veterans Affairs. The findings of this study are useful in understanding the needs of OEF/OIF veterans.

  3. Ethical challenges facing veterinary professionals in Ireland: results from Policy Delphi with vignette methodology

    PubMed Central

    Magalhães-Sant'Ana, M.; More, S. J.; Morton, D. B.; Hanlon, A.

    2016-01-01

    Ethics is key to the integrity of the veterinary profession. Despite its importance, there is a lack of applied research on the range of ethical challenges faced by veterinarians. A three round Policy Delphi with vignette methodology was used to record the diversity of views on ethical challenges faced by veterinary professionals in Ireland. Forty experts, comprising veterinary practitioners, inspectors and nurses, accepted to participate. In round 1, twenty vignettes describing a variety of ethically challenging veterinary scenarios were ranked in terms of ethical acceptability, reputational risk and perceived standards of practice. Round 2 aimed at characterising challenges where future policy development or professional guidance was deemed to be needed. In round 3, possible solutions to key challenges were explored. Results suggest that current rules and regulations are insufficient to ensure best veterinary practices and that a collective approach is needed to harness workable solutions for the identified ethical challenges. Challenges pertaining mostly to the food chain seem to require enforcement measures whereas softer measures that promote professional discretion were preferred to address challenges dealing with veterinary clinical services. These findings can support veterinary representative bodies, advisory committees and regulatory authorities in their decision making, policy and regulation. PMID:27613779

  4. Examining the Challenging Hindrances facing in the Construction Projects: South India’s Perspective

    NASA Astrophysics Data System (ADS)

    Subramanyam, K.; Haridharan, M. K.

    2017-07-01

    Developing countries like India require a huge infrastructure to facilitate needs of the people. Construction industry provides several opportunities to the individuals. Construction manager work is to supervise and organize the construction activities in construction projects. Now a day construction manager facing challenges. This paper aimed to study the challenges facing by the construction manager in the perception of construction professionals. 39 variables were taken from the literature review which found to be severe impact on construction managers’ performance. Construction manager, project manager and site engineers are the respondents for this survey. Using SPSS, regression analysis was done and recognized significant challenges. These challenges were classified into 5 domains. In management challenges, resource availability and allocation, risks and uncertainties existing in the project onsite, top management support and cost constraints are the most significant variables. In skills requirement of a construction manager challenges, technical skills required to learn and adapt new technology in the project, decision making and planning according to the situation in site are the most significant variables. In performance challenges, implementation of tasks according to the plan is the important variable whereas in onsite challenges, manage project risks, develop project policies and procedures are the most important.

  5. Ethical challenges facing veterinary professionals in Ireland: results from Policy Delphi with vignette methodology.

    PubMed

    Magalhães-Sant'Ana, M; More, S J; Morton, D B; Hanlon, A

    2016-10-29

    Ethics is key to the integrity of the veterinary profession. Despite its importance, there is a lack of applied research on the range of ethical challenges faced by veterinarians. A three round Policy Delphi with vignette methodology was used to record the diversity of views on ethical challenges faced by veterinary professionals in Ireland. Forty experts, comprising veterinary practitioners, inspectors and nurses, accepted to participate. In round 1, twenty vignettes describing a variety of ethically challenging veterinary scenarios were ranked in terms of ethical acceptability, reputational risk and perceived standards of practice. Round 2 aimed at characterising challenges where future policy development or professional guidance was deemed to be needed. In round 3, possible solutions to key challenges were explored. Results suggest that current rules and regulations are insufficient to ensure best veterinary practices and that a collective approach is needed to harness workable solutions for the identified ethical challenges. Challenges pertaining mostly to the food chain seem to require enforcement measures whereas softer measures that promote professional discretion were preferred to address challenges dealing with veterinary clinical services. These findings can support veterinary representative bodies, advisory committees and regulatory authorities in their decision making, policy and regulation. British Veterinary Association.

  6. Challenges facing developers of CAD/CAM models that seek to predict human working postures

    NASA Astrophysics Data System (ADS)

    Wiker, Steven F.

    2005-11-01

    This paper outlines the need for development of human posture prediction models for Computer Aided Design (CAD) and Computer Aided Manufacturing (CAM) design applications in product, facility and work design. Challenges facing developers of posture prediction algorithms are presented and discussed.

  7. Challenges Facing Early Childhood Programs Worldwide

    ERIC Educational Resources Information Center

    Neugebauer, Roger

    2008-01-01

    In this article, the author presents the challenges faced by early childhood education in 29 countries, according to the World Forum National Representatives and Global Leaders for Young Children. The countries represented in these responses include: Azerbaijan, Bangladesh, Bolivia, Brazil, Canada, Denmark, Egypt, Fiji, India, Iran, Iraq, Japan,…

  8. Exploring Biotechnology Using Case-Based Multimedia

    ERIC Educational Resources Information Center

    Bergland, Mark; Lundeberg, Mary; Klyczek, Karen; Sweet, Jennifer; Emmons, Jean; Martin, Christine; Marsh, Katherine; Werner, Joy; Jarvis-Uetz, Michelle

    2006-01-01

    Today, teachers face more challenges than ever, and biology teachers face a special challenge. As technology continues to expand, biology teachers have a responsibility to keep students informed of technological and scientific advances. Biology teachers must also address ethical issues associated with these advances. In this paper, the authors…

  9. Molecular Tumor Boards: Ethical Issues in the New Era of Data Medicine.

    PubMed

    Stoeklé, Henri-Corto; Mamzer-Bruneel, Marie-France; Frouart, Charles-Henry; Le Tourneau, Christophe; Laurent-Puig, Pierre; Vogt, Guillaume; Hervé, Christian

    2018-02-01

    The practice and development of modern medicine requires large amounts of data, particularly in the domain of cancer. The future of personalized medicine lies neither with "genomic medicine" nor with "precision medicine", but with "data medicine" (DM) (big data, data mining). The establishment of this DM has required far-reaching changes, to establish four essential elements connecting patients and doctors: biobanks, databases, bioinformatic platforms and genomic platforms. The "transformation" of scientific research areas, such as genetics, bioinformatics and biostatistics, into clinical specialties has generated a new vision of care. Molecular tumor boards (MTB) are one response to these changes and are now providing better access to next-generation sequencing (NGS) and new cancer treatments to patients with inoperable or metastatic cancers, and those for whom the usual treatment has failed. However, MTB face a crucial ethical challenge: maintaining and improving the trust of patients, clinicians, researchers and industry in academic medical centers supported by private or public funding rather than providing genetic data directly to private companies. We believe that, in this era of DM, appropriate modern digital communication networks will be required to maintain this trust and to improve the organization and effectiveness of the system. There is, therefore, a need to reconsider the form and content of informed consent (IC) documents at all academic medical centers and to introduce dynamic and electronic informed consent (e-IC).

  10. Biological mode of action of a nitrophenolates-based biostimulant: case study

    PubMed Central

    Przybysz, Arkadiusz; Gawrońska, Helena; Gajc-Wolska, Janina

    2014-01-01

    The challenges facing modern plant production involve (i) responding to the demand for food and resources of plant origin from the world's rapidly growing population, (ii) coping with the negative impact of stressful conditions mainly due to anthropopressure, and (iii) meeting consumers' new requirements and preferences for food that is high in nutritive value, natural, and free from harmful chemical additives. Despite employing the most modern plant cultivation technologies and the progress that has been made in breeding programs, the genetically-determined crop potential is still far from being fully exploited. Consequently yield and quality are often reduced, making production less, both profitable and attractive. There is an increasing desire to reduce the chemical input in agriculture and there has been a change toward integrated plant management and sustainable, environmentally-friendly systems. Biostimulants are a category of relatively new products of diverse formulations that positively affect a plant's vital processes and whose impact is usually more evident under stressful conditions. In this paper, information is provided on the mode of action of a nitrophenolates-based biostimulant, Atonik, in model species and economically important crops grown under both field and controlled conditions in a growth chamber. The effects of Atonik on plant morphology, physiology, biochemistry (crops and model plant) and yield and yield parameters (crops) is demonstrated. Effects of other biostimulants on studied in this work processes/parameters are also presented in discussion. PMID:25566287

  11. Biological mode of action of a nitrophenolates-based biostimulant: case study.

    PubMed

    Przybysz, Arkadiusz; Gawrońska, Helena; Gajc-Wolska, Janina

    2014-01-01

    The challenges facing modern plant production involve (i) responding to the demand for food and resources of plant origin from the world's rapidly growing population, (ii) coping with the negative impact of stressful conditions mainly due to anthropopressure, and (iii) meeting consumers' new requirements and preferences for food that is high in nutritive value, natural, and free from harmful chemical additives. Despite employing the most modern plant cultivation technologies and the progress that has been made in breeding programs, the genetically-determined crop potential is still far from being fully exploited. Consequently yield and quality are often reduced, making production less, both profitable and attractive. There is an increasing desire to reduce the chemical input in agriculture and there has been a change toward integrated plant management and sustainable, environmentally-friendly systems. Biostimulants are a category of relatively new products of diverse formulations that positively affect a plant's vital processes and whose impact is usually more evident under stressful conditions. In this paper, information is provided on the mode of action of a nitrophenolates-based biostimulant, Atonik, in model species and economically important crops grown under both field and controlled conditions in a growth chamber. The effects of Atonik on plant morphology, physiology, biochemistry (crops and model plant) and yield and yield parameters (crops) is demonstrated. Effects of other biostimulants on studied in this work processes/parameters are also presented in discussion.

  12. Development of Critical Thinking Skills through Writing Tasks: Challenges Facing Maritime English Students at Aqaba College, AlBalqa Applied University, Jordan

    ERIC Educational Resources Information Center

    Alidmat, Ali Odeh Hammoud; Ayassrah, Mohamed Ayed

    2017-01-01

    Teaching English for Special Purposes (ESP) in a context where English is taught as a Foreign Language (EFL) is no easy task. There is in fact extensive research reporting on challenges facing both teacher and student in the Foreign Language classroom where language skills must be learnt outside their usual context. Even more challenging is…

  13. Exploring strategies to overcome extra-organisational challenges faced by community pharmacies in Sarawak, Malaysia.

    PubMed

    Kho, Boon Phiaw; Hassali, Mohamed Azmi; Lim, Ching Jou; Saleem, Fahad

    2018-03-15

    The aims of this research were to determine extra-organisational challenges (e.g. market competition, governing policies) faced by community pharmacies in Sarawak, the coping strategies employed to deal with these challenges and explore potential legislative changes that can attenuate the intensity of these challenges. Survey questionnaires (n = 184) were posted to all eligible community pharmacies in Sarawak, Malaysia. The questionnaire included sections on participants' demographic data, extra-organisational challenges faced, coping strategies employed and proposals to improve community pharmacy legislations. Items were constructed based on the findings of a prior qualitative research supplemented with relevant literature about these issues. High levels of homogeneity in responses were recorded on various extra-organisational challenges faced, particularly those economy-oriented. Strategic changes to counter these challenges were focused on pricing and product stocked, rather than services provision. Highly rated strategies included increasing discounts for customers (n = 54; 68%) and finding cheaper suppliers (n = 70; 88%). Legislative changes proposed that might increase their share of the pharmaceutical market were strongly supported by respondents, particularly about making it compulsory for general practitioners to provide patients the option to have their medicines dispensed in community pharmacies (n = 72; 90%). Current legislative conditions and Malaysian consumer mindset may have constrained the strategic choices of community pharmacies to deal with the strong extra-organisational challenges. A long-term multipronged approach to address these issues and increased involvement of community pharmacists themselves in this agenda are required to influence practice change. © 2018 Royal Pharmaceutical Society.

  14. COOP+ project: Promoting the cooperation of international Research Infrastructures to address global environmental challenges.

    NASA Astrophysics Data System (ADS)

    Bonet-García, F.; Järvi, L.; Asmi, A.; Suárez-Muñoz, M.

    2016-12-01

    Humanity must face enormous environmental challenges including biodiversity decline, climate change, ocean acidification, sea level rise and overpopulation. The research infrastructures (RIs) created in the last decades worldwide cover a wide range of spatial and thematic scales and collect information about the functioning of Earth ecosystems. However, we need to go one step forward: understand and simulate the functioning of the Earth as a complex system in a global change scenario. Cooperation among international RIs as well as multidisciplinary work are mandatory to achieve this challenging objective. COOP+ (EU Horizon 2020 project) aims to strengthen the links and coordination of European environmental RIs with their international counterparts. COOP+ will create cooperation threads among international research infrastructures using environmental Global Challenges (GCs) as thematic guidelines. These GCs are polyhedral and sometimes wicked problems that threaten the sustainability of our modern societies from a social and environmental perspective. This contribution describes how COOP+ uses GCs as guidelines to foster cooperation among RIs. First we have created an open survey to collect ideas about GCs within the different scientific communities. We present the structure of this survey as well as the preliminary information that it contains. The survey will be accepting responses during the project life (September 2018). We also describe the structure of a template that will be used to collaboratively characterize some selected GCs under the point of view of RIs. The main idea is to assess how RIs can be useful to address global environmental problems. We encourage all scientists related to RIs communities to participate in this process.

  15. Earthquake hazards in the Alaska transportation corridors

    DOT National Transportation Integrated Search

    1983-03-01

    Based on observations made by modern seismographic networks since 1967, and taking into consideration historical records of large Alaskan earthquakes in the past, it is judged that the hazards faced by transportation corridors in different areas of t...

  16. A Clash of Military Traditions: Meritocracy, Modernization, and Neo-Traditional Challenges to the United States of America’s Foreign Internal Defense (FID) Policy

    DTIC Science & Technology

    2009-12-01

    THEORIES OF FID........................................4 C. FID IN ACTION AND THE NEO-TRADITIONAL CHALLENGE.......10 D. SUMMARY...examination of the still very limited research that focuses explicitly on FID, while also discussing related 2 works on the theory and practice of nation...building and state-building. This is followed by a more detailed evaluation of some of the key theories of modernization, development, and state

  17. Multi-Institution Research Centers: Planning and Management Challenges

    ERIC Educational Resources Information Center

    Spooner, Catherine; Lavey, Lisa; Mukuka, Chilandu; Eames-Brown, Rosslyn

    2016-01-01

    Funding multi-institution centers of research excellence (CREs) has become a common means of supporting collaborative partnerships to address specific research topics. However, there is little guidance for those planning or managing a multi-institution CRE, which faces specific challenges not faced by single-institution research centers. We…

  18. Internationalising Teacher Education for a "Glocal" Curriculum: South Koreans Learning to Teach Hong Kong Liberal Studies

    ERIC Educational Resources Information Center

    Jackson, Liz; Han, Ana Yoon Jin

    2016-01-01

    Internationalisation in education facilitates student and teacher mobility. Though Hong Kong has embraced internationalisation in education, international university students can face challenges related to cultural difference. In teacher education, these challenges can be amplified, as student-teachers face expectations to teach schoolchildren…

  19. Anger and Globalization among Young People in India

    ERIC Educational Resources Information Center

    Suchday, Sonia

    2015-01-01

    This article addresses the challenges faced by youth in developing countries. Using India as an example of a fast-globalizing country, this article highlights the experience and challenges faced by adolescents and emerging adults as they search for their interpersonal and professional identities. The difficulties of defining identity in the…

  20. The Challenges Facing Catholic Education in France Today

    ERIC Educational Resources Information Center

    Moog, François

    2016-01-01

    The effects of secularisation on society demand a rethinking of the identity and mission of Catholic schools in France. In 2013, the French bishops published a new directory which offers new approaches, described here, based on the three challenges facing Catholic education in France: linking social responsibility and evangelisation, setting up…

  1. An Inventory and Use Analysis of Information Systems on Small Farms in Pennsylvania

    ERIC Educational Resources Information Center

    Adams, Jean S.

    2007-01-01

    Across the United States, today's farm operators face continuing challenges from global competition, increasing production costs, changing technology, increased regulations, scarce resources, and lower profit margins. To face these challenges, farm operators need to gather and utilize information allowing them to make informed decisions. Several…

  2. Anatomy Education Faces Challenges in Pakistan

    ERIC Educational Resources Information Center

    Memon, Ismail K.

    2009-01-01

    Anatomy education in Pakistan is facing many of the same challenges as in other parts of the world. Roughly, a decade ago, all medical and dental colleges in Pakistan emphasized anatomy as a core basic discipline within a traditional medical science curriculum. Now institutions are adopting problem based learning (PBL) teaching philosophies, and…

  3. Many Faces Have I.

    ERIC Educational Resources Information Center

    Zilliox, Joseph T.; Lowery, Shannon G.

    1997-01-01

    Describes an extended investigation of polygons and polyhedra which was conducted in response to a challenge posed in Focus, a newsletter from the Mathematical Association of America (MAA). Students were challenged to construct a polyhedron with faces that measure more than 13 inches to a side. Outlines the process, including the questions posed…

  4. Women Superintendents in Illinois: Gender Barriers and Challenges

    ERIC Educational Resources Information Center

    VanTuyle, Vicki; Watkins, Sandra G.

    2009-01-01

    Women face unique challenges as superintendents. This study determined barriers women face as superintendents and elicited reasons why these women would consider leaving the superintendent's position. Thirty-nine PreK-12 women superintendents in Illinois participated in a web-based survey in January 2008. Survey items included information…

  5. Plural Societies and the Possibility of Shared Citizenship

    ERIC Educational Resources Information Center

    Merry, Michael S.

    2012-01-01

    As civilization pushes headlong into the twenty-first century, increasingly stringent demands for citizenship issue forth from governments around the world faced with a formidable assortment of challenges. Faced with these challenges, states are exploring ways to elicit civic attachments from their heterogeneous populations, but doing so is…

  6. Challenges Facing Principals in the First Year at Their Schools

    ERIC Educational Resources Information Center

    Bayar, Adem

    2016-01-01

    The aim of this study is to identify key challenges of practice that principals face. In line with this purpose, the researcher has employed a qualitative research methodology, interviewing principals working in Amasya district, over and above doing document analysis to collect detailed information concerning leadership and administration…

  7. Perspectives on Urban Geography in Advanced Placement® Human Geography

    ERIC Educational Resources Information Center

    Benton-Short, Lisa; Monk, Liliana

    2016-01-01

    "Perspectives on Urban Geography" constitutes a major part of the AP Human Geography course outline. In this article, urban core revitalization and rising suburban poverty are considered as two challenges facing cities in developed countries; and industrialization and the growth of megacities as two challenges facing cities in developing…

  8. Homeless Children: Meeting the Educational Challenges. ERIC Digest.

    ERIC Educational Resources Information Center

    Goins, Brad; Cesarone, Bernard

    Difficulties faced by homeless children include depression, low self-esteem, lack of sleep and nutrition, and feelings of shame and embarrassment. Challenges faced by schools in providing education to homeless children include: (1) keeping children in one school despite frequent family moves; (2) ensuring that children's health records are…

  9. The Big Picture and Specifics of College General Education

    ERIC Educational Resources Information Center

    Gan, Yang

    2018-01-01

    In recent years, general education has developed considerably in Chinese universities, but it still faces many challenges and problems. Among the various negative factors, four problems may be the greatest challenges currently faced by Chinese university general education and ordinary undergraduate education: (1) In the era of massified higher…

  10. Autism and Reading: Teaching a Sudanese Refugee Boy

    ERIC Educational Resources Information Center

    Walker-Dalhouse, Doris; Dalhouse, A. Derick

    2015-01-01

    Refugee families in the United States face numerous challenges in becoming acculturated. School-age children of refugees face the additional challenges of acquiring academic language and meeting school expectations for behavior and social interactions while attempting to navigate the school curriculum. This case study examines the school and home…

  11. Part I. Synthesis and Characterization of Donor-Pi-Acceptor Compounds with Pentadienyl-Bridged Indoline and Tetrahydroquinoline Donors and Aldehyde and Thiobarbituric Acid Acceptors Part II. Longitudinal Study Comparing Online versus Face-to-Face Course Delivery in Introductory Chemistry

    ERIC Educational Resources Information Center

    Greco, Patrick F.

    2012-01-01

    Part I. The design and development of organic second-order nonlinear optical (NLO) materials have attracted much interest due to their applications in optoelectronic devices and modern communications technology. Donor-pi-acceptor compounds, D-(CH=CH)[subscript n]-A, often exhibit hyperpolarizability that results in laser frequency doubling (second…

  12. Missed Opportunities for Science Learning: Unacknowledged Unscientific Arguments in Asynchronous Online and Face-to-Face Discussions

    NASA Astrophysics Data System (ADS)

    Callis-Duehl, Kristine; Idsardi, Robert; Humphrey, Eve A.; Gougis, Rebekka Darner

    2018-02-01

    We explored the scientific argumentation that occurs among university biology students during an argumentation task implemented in two environments: face-to-face in a classroom and online in an asynchronous discussion. We observed 10 student groups, each composed of three students. Our analysis focused on how students respond to their peers' unscientific arguments, which we define as assertions, hypotheses, propositions, or explanations that are inaccurate or incomplete from a scientific perspective. Unscientific arguments provide opportunities for productive dissent, scientific argumentation, and conceptual development of scientifically desirable conceptions. We found that students did not respond to the majority of unscientific arguments in both environments. Challenges to unscientific arguments were expressed as a question or through explanation, although the latter was more common online than face-to-face. Students demonstrated significantly more epistemic distancing in the face-to-face environment than the online environment. We discuss the differences in discourse observed in both environments and teaching implications. We also provide direction for future research seeking to address the challenges of engaging students in productive scientific argumentation in both face-to-face and online environments.

  13. Music or Musics? An Important Matter at Hand

    ERIC Educational Resources Information Center

    Goble, J. Scott

    2015-01-01

    Philosophers of music education presently find themselves suspended between modernism's universalist convictions and post-modernism's cultural relativist insights. In "Music Matters: A New Philosophy of Music Education" (1995), David Elliott challenged longstanding conceptions of "music education as aesthetic education" to…

  14. Voicing the Challenges Faced by an Innovative Teacher Community

    ERIC Educational Resources Information Center

    Moate, Josephine

    2011-01-01

    This research draws on sociocultural theories of learning and activity theory to explore the challenges faced by an innovative community of teachers in Central Finland. The aim of the teacher community was to develop a stream of foreign-language (FL)-mediated teaching and learning in the locality from kindergarten to upper secondary level. To…

  15. Oral Academic Discourse Socialisation: Challenges Faced by International Undergraduate Students in a Malaysian Public University

    ERIC Educational Resources Information Center

    Mahfoodh, Omer Hassan Ali

    2014-01-01

    This paper reports a qualitative study which examines the challenges faced by six international undergraduate students in their socialisation of oral academic discourse in a Malaysian public university. Data were collected employing interviews. Students' presentations were also collected. Semi-structured interviews were transcribed verbatim and…

  16. Connecting Pre-Service Teachers with Contemporary Mathematics Practices: Selecting and Sequencing Students' Work Samples

    ERIC Educational Resources Information Center

    Livy, Sharyn; Muir, Tracey; Downton, Ann

    2017-01-01

    One of the challenges facing teacher educators is providing our pre-service teachers (PSTs) with authentic experiences that cross the boundaries between Initial Teacher Education (ITE) and the classroom. An additional challenge facing the mathematics teacher educator, is addressing and deepening PSTs' mathematical content knowledge (MCK), which…

  17. Information Technology Challenges Facing the Strategic Leaders of Homeland Security in the 21st Century

    DTIC Science & Technology

    2004-05-03

    A special thanks to all of these folks (Glenn Starnes, Lee Gutierrez, Bill Rapp, Joel Hillison, Carlos Gomez, Steve Fraunfelter, Janie Hopkins, Dave ...DiClemente, Joe Nunez, John Bonin , and Steve Nerheim). viii INFORMATION TECHNOLOGY CHALLENGES FACING THE STRATEGIC LEADERS OF HOMELAND SECURITY IN THE 21ST

  18. Strategies for the Challenges Facing Women in Higher Education Administration.

    ERIC Educational Resources Information Center

    Rehnke, Mary Ann

    Women administrators in higher education must deal not only with the usual challenges facing administrators (decision-making, resolving conflict, and advancing professionally), but also with the effects of sex stereotyping. Women are not seen as decision-makers, nor as conflict-resolvers, and are often viewed as supporting personnel rather than…

  19. Tenured Women Counselor Educators at Research Universities: Navigating Multiple Roles and Personal Well-Being

    ERIC Educational Resources Information Center

    Rosenberg, Melissa A.

    2013-01-01

    Women in academia navigate multiple professional and personal roles, and may face unique challenges to integrate their intellectual, emotional, physical, and spiritual selves. The narrative of constraint underscores the disadvantages, challenges, and inequities that women who are mothers and academics face in their lives. This lack of privilege…

  20. Integration and Career Challenges of Newcomer Youth in Newfoundland in Canada

    ERIC Educational Resources Information Center

    Li, Xuemei; Que, Hua

    2016-01-01

    Faced with a labor shortage and low profile of diversity, the province of Newfoundland and Labrador in Canada has been making an effort to attract and retain newcomers. Guided by Bronfenbrenner's (1979) ecological systems theory, this qualitative study investigates the challenges faced by newcomer youth, including permanent residents coming as…

  1. "Accounting Education at a Crossroad in 2010" and "Challenges Facing Accounting Education in Australia"

    ERIC Educational Resources Information Center

    de Lange, Paul; Watty, Kim

    2011-01-01

    Of the various reports released in 2010, two purport to examine the state of accounting education in Australia. These are "Accounting Education at a Crossroad in 2010" and "Challenges Facing Accounting Education in Australia". Both were released as collaborations of the leading academic organisation, the Accounting and Finance…

  2. A Business Intelligence Framework for Sustainability Information Management in Higher Education

    ERIC Educational Resources Information Center

    Scholtz, Brenda; Calitz, Andre; Haupt, Ross

    2018-01-01

    Purpose: Higher education institutions (HEIs) face a number of challenges in effectively managing and reporting on sustainability information, such as siloes of data and a limited distribution of information. Business intelligence (BI) can assist in addressing the challenges faced by organisations. The purpose of this study was to propose a BI…

  3. Active Learning: Engaging Students to Maximize Learning in an Online Course

    ERIC Educational Resources Information Center

    Khan, Arshia; Egbue, Ona; Palkie, Brooke; Madden, Janna

    2017-01-01

    Student engagement is key to successful teaching and learning, irrespective of the content and format of the content delivery mechanism. However, engaging students presents a particular challenge in online learning environments. Unlike face-to-face courses, online courses present a unique challenge as the only social presence between the faculty…

  4. Can Free-Range Students Save Some Schools? A Case Study on a Hybrid Classroom

    ERIC Educational Resources Information Center

    White, Christopher Francis

    2013-01-01

    In the face of budgetary constraints, new marketplace competition, digital innovation and an emerging generation of students with new demands and new needs, higher education in America is challenged as never before. This paper reviews the various challenges facing traditional non-profit educational institutions, considers the potential of an…

  5. Calculus Challenges: An Active Learning Approach

    ERIC Educational Resources Information Center

    Crawford, Pam; Moseley, Daniel; Nancarrow, Mike; Ward, Erika

    2018-01-01

    One of the greatest challenges facing students new to calculus is the ability to persevere in the face of failure. Whether the student is choosing an integration technique or a series test, calculus is often the first course in mathematics where the path to the solution is not prescribed in an algorithmic way. At Jacksonville University we…

  6. Challenges Faced by Institutions of Higher Education in Migrating to Distance Learning.

    ERIC Educational Resources Information Center

    Broskoske, Stephen L.; Harvey, Francis A.

    This paper presents the results of a research study conducted in fall 1999 to examine the challenges facing higher educational institutions in migrating to distance learning. The study consisted of five case studies conducted at higher educational institutions in Pennsylvania. At each institution the researchers interviewed the president and other…

  7. The Complexity of Substantive Reform: A Call for Interdependence among Key Stakeholders.

    ERIC Educational Resources Information Center

    Young, Michelle D.; Petersen, George J.; Short, Paula M.

    The field of educational leadership faces serious challenges in the 21st century, such as the shortage of principals and superintendents, the growing demands for leadership positions, and the struggle for adequate resources. This paper explores the challenges facing this field from the position of university educational leadership preparation. The…

  8. Meeting the Needs of Children and Families: Opportunities and Challenges for School Psychology Training Programs.

    ERIC Educational Resources Information Center

    Curtis, Michael J.; Batsche, George M.

    1991-01-01

    Notes that graduate training programs face challenges, as well as opportunities, in fulfillment of their responsibilities to prepare school psychologists for entry into professional practice. Examines nature and origins of potential changes facing school psychology and discusses adequacy of current training programs. Discusses future implications…

  9. Community Violence Exposure of Southeast Asian American Adolescents

    ERIC Educational Resources Information Center

    Ho, Joyce

    2008-01-01

    Southeast Asian adolescents in the United States face the daily challenge of adjusting to the American culture and their culture of origin. However, little is known about how the patterns of their bicultural adjustment influence psychological symptoms, especially when faced with other challenges such as community violence and negative life events.…

  10. Preserving Guam's Culture with Culturally Responsive Children's Stories

    ERIC Educational Resources Information Center

    Jackson, Marilyn Malloy; Heath, Melissa Allen

    2017-01-01

    Regardless of where schools are located, teachers face the challenge of teaching and mentoring children, not only in academic achievement but in social emotional development. When faced with challenges, young children are especially vulnerable because they lack the life experience and developmental maturity to adequately cope. Relying on the lead…

  11. New Challenges Facing Universities in the Internet-Driven Global Environment

    ERIC Educational Resources Information Center

    Rajasingham, Lalita

    2011-01-01

    This paper explores some new challenges facing universities in a global multimediated Internet-based environment, as they seek alternative paradigms and options to remain true to their core business. At a time of rapid technological change, and contested, complex concepts associated with globalisation, knowledge is becoming a primary factor of…

  12. Curricular Integration and Measurement of Cultural Competence Development in a Group of Physical Therapy Students

    ERIC Educational Resources Information Center

    Palombaro, Kerstin M.; Dole, Robin L.; Black, Jill D.

    2015-01-01

    Introduction and Background: The link between cultural competence and effective physical therapy encounters is established. Physical therapist educational programs face the challenge of fostering the cultural competence of students in effective and meaningful ways within the curriculum. They also face the challenge of measuring the development of…

  13. Career Development with Transgender College Students: Implications for Career and Employment Counselors

    ERIC Educational Resources Information Center

    Scott, David A.; Belke, Stephanie L.; Barfield, Hannah G.

    2011-01-01

    The number of transgender college students continues to increase every year. These students face unique challenges that many college and university career centers are not prepared to handle. This article describes some of the challenges facing transgender students and college career centers. A professional development design is proposed to assist…

  14. Quality Assurance Challenges and Opportunities Faced by Private Universities in Zimbabwe

    ERIC Educational Resources Information Center

    Garwe, Evelyn Chiyevo

    2014-01-01

    The study sought to provide an understanding of the quality assurance challenges and opportunities faced by private universities in Zimbabwe. The study analyzed the factors determining provision of quality higher education in private universities and the resultant effects of failing to achieve the minimum acceptable standards. The author employed…

  15. Challenges and Opportunities Facing Technology Education in Taiwan

    ERIC Educational Resources Information Center

    Lee, Lung-Sheng Steven

    2009-01-01

    The technology education in Taiwan is prescribed in the national curriculum and provided to all students in grades 1-12. However, it faces the following challenges: (1) Lack of worthy image, (2) Inadequate teachers in elementary schools, (3) Deficient teaching vitality in secondary schools, and (4) Diluted technology teacher education programs. In…

  16. Challenges Faced by Teachers Implementing Socio-Scientific Issues as Core Elements in Their Classroom Practices

    ERIC Educational Resources Information Center

    Bossér, Ulrika; Lundin, Mattias; Lindahl, Mats; Linder, Cedric

    2015-01-01

    Teachers may face considerable challenges when implementing socio-scientific issues (SSI) in their classroom practices, such as incorporating student-centred teaching practices and exploring knowledge and values in the context of socioscientific issues. This year-long study explores teachers' reflections on the process of developing their…

  17. Challenges Facing Women Academic Leadership in Secondary Schools of Irbid Educational Area

    ERIC Educational Resources Information Center

    Al-Jaradat, Mahmoud Khaled Mohammad

    2014-01-01

    This study aimed at identifying the challenges facing women academic leadership in secondary schools of Irbid Educational Area. A random sample of 187 female leaders were chosen. They responded to a 49-item questionnaire prepared by the researcher. The items were distributed into four domains: organizational, personal, social and physical…

  18. Executive Leadership: Another Lever in the System?

    ERIC Educational Resources Information Center

    Harris, Alma; Brown, David; Abbott, Ian

    2006-01-01

    The leadership challenges facing most head teachers can at times be daunting but for those leading schools in difficulty, the challenges are acute. This article draws upon the personal experience of an executive leader in a school facing difficult circumstances. It will firstly, outline and analyse this model of leadership and secondly, look at…

  19. TQM in a Multi-Campus Public University.

    ERIC Educational Resources Information Center

    Zargar, Ali M.

    Running a university is fast becoming more challenging than managing a large corporation, in part due to greater quality demands by more groups in the face of shrinking resources and budget cuts. This paper argues against universities conducting business as usual in the face of societal change and increasingly greater challenges, and presents…

  20. Information Assurance and Forensic Readiness

    NASA Astrophysics Data System (ADS)

    Pangalos, Georgios; Katos, Vasilios

    Egalitarianism and justice are amongst the core attributes of a democratic regime and should be also secured in an e-democratic setting. As such, the rise of computer related offenses pose a threat to the fundamental aspects of e-democracy and e-governance. Digital forensics are a key component for protecting and enabling the underlying (e-)democratic values and therefore forensic readiness should be considered in an e-democratic setting. This position paper commences from the observation that the density of compliance and potential litigation activities is monotonically increasing in modern organizations, as rules, legislative regulations and policies are being constantly added to the corporate environment. Forensic practices seem to be departing from the niche of law enforcement and are becoming a business function and infrastructural component, posing new challenges to the security professionals. Having no a priori knowledge on whether a security related event or corporate policy violation will lead to litigation, we advocate that computer forensics need to be applied to all investigatory, monitoring and auditing activities. This would result into an inflation of the responsibilities of the Information Security Officer. After exploring some commonalities and differences between IS audit and computer forensics, we present a list of strategic challenges the organization and, in effect, the IS security and audit practitioner will face.

  1. An ICT-Based Diabetes Management System Tested for Health Care Delivery in the African Context.

    PubMed

    Takenga, Claude; Berndt, Rolf-Dietrich; Musongya, Olivier; Kitero, Joël; Katoke, Remi; Molo, Kakule; Kazingufu, Basile; Meni, Malikwisha; Vikandy, Mambo; Takenga, Henri

    2014-01-01

    The demand for new healthcare services is growing rapidly. Improving accessibility of the African population to diabetes care seems to be a big challenge in most countries where the number of care centers and medical staff is reduced. Information and communication technologies (ICT) have great potential to address some of these challenges faced by several countries in providing accessible, cost-effective, and high-quality health care services. This paper presents the Mobil Diab system which is a telemedical approach proposed for the management of long-term diseases. The system applies modern mobile and web technologies which overcome geographical barriers, and increase access to health care services. The idea of the system is to involve patients in the therapy process and motivate them for an active participation. For validation of the system in African context, a trial was conducted in the Democratic Republic of Congo. 40 Subjects with diabetes divided randomly into control and intervention groups were included in the test. Results show that Mobil Diab is suitable for African countries and presents a number of benefits for the population and public health care system. It improves clinical management and delivery of diabetes care services by enhancing access, quality, motivation, reassurance, efficiency, and cost-effectiveness.

  2. ‘Plue plun’ male, ‘kath klei’ female: gender differences in suicidal behavior as expressed by young people in Cambodia

    PubMed Central

    Jegannathan, Bhoomikumar; Dahlblom, Kjerstin; Kullgren, Gunnar

    2013-01-01

    Few studies from low- and middle-income countries use qualitative methodology to explore suicidal behavior among young people. In Cambodia, young people face the challenge of rapidly changing times and are vulnerable for suicidal behavior as revealed by research in transitional economies. This study seeks to gain a deeper understanding of the suicidal phenomena from a gender, psychosocial and cultural perspective. Six focus-group discussions were conducted among boys and girls, aged 15–19 years, in two secondary schools in a suburban area close to Phnom Penh, the capital city. The data was analyzed using thematic analysis approach. The participants highlighted the gender difference in suicidal behavior by describing the suicide-prone, acting-out male as ‘plue plun’, while suicide-prone females were described as caught in constricted, tunneled-thinking behavior, expressed as ‘kath klei’. Parental attitude and family environment were also pointed out as the chief causes of discontent and there was a strong wish on the part of young people to find space for modern values within the traditional family. The young people's awareness of their challenges in everyday life suggests that school-based programs to prevent suicidal behavior ought to be gender-sensitive and peer-focused. PMID:24999370

  3. An ICT-Based Diabetes Management System Tested for Health Care Delivery in the African Context

    PubMed Central

    Takenga, Claude; Berndt, Rolf-Dietrich; Musongya, Olivier; Kitero, Joël; Katoke, Remi; Molo, Kakule; Kazingufu, Basile; Meni, Malikwisha; Vikandy, Mambo; Takenga, Henri

    2014-01-01

    The demand for new healthcare services is growing rapidly. Improving accessibility of the African population to diabetes care seems to be a big challenge in most countries where the number of care centers and medical staff is reduced. Information and communication technologies (ICT) have great potential to address some of these challenges faced by several countries in providing accessible, cost-effective, and high-quality health care services. This paper presents the Mobil Diab system which is a telemedical approach proposed for the management of long-term diseases. The system applies modern mobile and web technologies which overcome geographical barriers, and increase access to health care services. The idea of the system is to involve patients in the therapy process and motivate them for an active participation. For validation of the system in African context, a trial was conducted in the Democratic Republic of Congo. 40 Subjects with diabetes divided randomly into control and intervention groups were included in the test. Results show that Mobil Diab is suitable for African countries and presents a number of benefits for the population and public health care system. It improves clinical management and delivery of diabetes care services by enhancing access, quality, motivation, reassurance, efficiency, and cost-effectiveness. PMID:25136358

  4. Developing Traditional Chinese Medicine in the Era of Evidence-Based Medicine: Current Evidences and Challenges

    PubMed Central

    Fung, Foon Yin; Linn, Yeh Ching

    2015-01-01

    Evidence-based medicine (EBM), by integrating individual clinical expertise with the best available clinical evidence from systematic research, has in recent years been established as the standard of modern medical practice for greater treatment efficacy and safety. Traditional Chinese Medicine (TCM), on the other hand, evolved as a system of medical practice from ancient China more than 2000 years ago based on empirical knowledge as well as theories and concepts which are yet to be mapped by scientific equivalents. Despite the expanding TCM usage and the recognition of its therapeutic benefits worldwide, the lack of robust evidence from the EBM perspective is hindering acceptance of TCM by the Western medicine community and its integration into mainstream healthcare. For TCM to become an integral component of the healthcare system so that its benefits can be rationally harnessed in the best interests of patients, it is essential for TCM to demonstrate its efficacy and safety by high-level evidence in accordance with EBM, though much debate remains on the validity and feasibility of applying the EBM model on this traditional practice. This review aims to discuss the current status of research in TCM, explore the evidences available on its efficacy and safety, and highlight the issues and challenges faced in applying EBM to TCM. PMID:25949261

  5. Challenges in healthcare delivery in an economic downturn, in the Republic of Ireland.

    PubMed

    Carney, Marie

    2010-07-01

    The purpose of the present study was to discuss some of effects of the downturn in the Irish economy and to demonstrate that in the face of economic difficulties innovation in health care is still occurring. Staff that are managing and delivering healthcare need to know the challenges facing them and have an awareness of the importance of maintaining interest in innovative practice in turbulent times. Information obtained from several sources including government papers, the nursing regulatory board and quality authority documents and current best practice articles. Information was evaluated based on the study's aim. Issues emerging were that current challenges facing Irish health care delivery relate mainly to economic, clinical management, education and information technology factors and further reductions in the cost base of health care delivery remains focused on value for money. In the face of the economic downturn Ireland is achieving health targets and is now sitting in 13th place on the European health index, down from number 28 in 2008. This improvement in position has resulted from several new innovative work practices. As a result of cost reduction measures in place nurse managers will face greater challenges than ever before in meeting the objectives of the healthcare transformation programme.

  6. Body Size as a Driver of Scavenging in Theropod Dinosaurs.

    PubMed

    Kane, Adam; Healy, Kevin; Ruxton, Graeme D; Jackson, Andrew L

    2016-06-01

    Theropod dinosaurs dominated Earth's terrestrial ecosystem as a diverse group of predators for more than 160 million years, yet little is known about their foraging ecology. Maintaining a balanced energy budget presented a major challenge for therapods, which ranged from the chicken-sized Microraptor up to the whale-sized Giganotosaurus, in the face of intense competition and the demands of ontogenetic growth. Facultative scavenging, a behavior present in almost all modern predators, may have been important in supplementing energetically expensive lifestyles. By using agent-based models based on the allometric relationship between size and foraging behaviors, we show that theropods between 27 and 1,044 kg would have gained a significant energetic advantage over individuals at both the small and large extremes of theropod body mass through their scavenging efficiency. These results were robust to rate of competition, primary productivity, and detection distance. Our models demonstrate the potential importance of facultative scavenging in theropods and the role of body size in defining its prevalence in Mesozoic terrestrial systems.

  7. The Public Health Community Platform, Electronic Case Reporting, and the Digital Bridge.

    PubMed

    Cooney, Mary Ann; Iademarco, Michael F; Huang, Monica; MacKenzie, William R; Davidson, Arthur J

    At the intersection of new technology advancements, ever-changing health policy, and fiscal constraints, public health agencies seek to leverage modern technical innovations and benefit from a more comprehensive and cooperative approach to transforming public health, health care, and other data into action. State health agencies recognized a way to advance population health was to integrate public health with clinical health data through electronic infectious disease case reporting. The Public Health Community Platform (PHCP) concept of bidirectional data flow and knowledge management became the foundation to build a cloud-based system connecting electronic health records to public health data for a select initial set of notifiable conditions. With challenges faced and lessons learned, significant progress was made and the PHCP grew into the Digital Bridge, a national governance model for systems change, bringing together software vendors, public health, and health care. As the model and technology advance together, opportunities to advance future connectivity solutions for both health care and public health will emerge.

  8. Eco-driving: behavioural pattern change in Polish passenger vehicle drivers

    NASA Astrophysics Data System (ADS)

    Czechowski, Piotr Oskar; Oniszczuk-Jastrząbek, Aneta; Czuba, Tomasz

    2018-01-01

    In Poland, as in the rest of Europe, air quality depends primarily on emissions from municipal, domestic and road transport sources. The problems of appropriate air quality are especially important within urban areas due to numerous sources of emissions being concentrated in relatively small spaces in both large cities and small/medium-sized towns. Due to the steadily increasing share of urban population in the overall number of population, the issue of providing clean air will over the years become a more significant problem for human health, and therefore a stronger incentive to intensify research. The key challenge faced by a modern society is, therefore, to limit harmful substance emissions in order to minimise the contribution of transport to pollution and health hazards. Increasingly stringent emission standards are being imposed on car manufacturers; on the other hand, scant regard is paid to the issue of drivers, i.e. how they can help reduce emissions and protect their life and health by applying eco-driving rules.

  9. [Does the emergence of antibiotic resistance announce the return of the dark ages?].

    PubMed

    Elhani, Dalèle

    2011-01-01

    Antibiotic revolution changed the course of modern medicine, by decreasing mortality due to bacterial infections. However, bacteria have developed several ways of resistance against all antibiotics used. In view of the rise of resistance and of its dissemination to different bacterial families, new effective antibiotics are scare and the return in the pre-antibiotic era seems to be a reality for some parts of the world. This review revises the worrying phenomenon of antibiotic resistance focusing on some examples of "superbugs", which represent a daily challenge for the medical profession, such as methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus, extended spectrum ß-lactamae-producing Enterobacteriaceae as well as carbapenem-resistant Pseudomonas aeruginosa. Facing the emergence of the multiresistant strains, the priority is obviously to control the spread of these microorganisms. It is only through the prudent use of antimicrobial drugs and the introduction of new and effective antibiotics that the antibiotic resistance will be slowed down and that we continue to treat bacterial infections.

  10. Multi-Time Step Service Restoration for Advanced Distribution Systems and Microgrids

    DOE PAGES

    Chen, Bo; Chen, Chen; Wang, Jianhui; ...

    2017-07-07

    Modern power systems are facing increased risk of disasters that can cause extended outages. The presence of remote control switches (RCSs), distributed generators (DGs), and energy storage systems (ESS) provides both challenges and opportunities for developing post-fault service restoration methodologies. Inter-temporal constraints of DGs, ESS, and loads under cold load pickup (CLPU) conditions impose extra complexity on problem formulation and solution. In this paper, a multi-time step service restoration methodology is proposed to optimally generate a sequence of control actions for controllable switches, ESSs, and dispatchable DGs to assist the system operator with decision making. The restoration sequence is determinedmore » to minimize the unserved customers by energizing the system step by step without violating operational constraints at each time step. The proposed methodology is formulated as a mixed-integer linear programming (MILP) model and can adapt to various operation conditions. Furthermore, the proposed method is validated through several case studies that are performed on modified IEEE 13-node and IEEE 123-node test feeders.« less

  11. The Holocaust and medical ethics: the voices of the victims.

    PubMed

    Jotkowitz, A

    2008-12-01

    Fifty-nine years ago, Dr Leo Alexander published his now famous report on medicine under the Nazis. In his report he describes the two major crimes of German physicians. The participation of physicians in euthanasia and genocide and the horrible experiments performed on concentration camp prisoners in the name of science. In response to this gross violation of human rights by physicians, the Nuremberg military tribunal, which investigated and prosecuted the perpetrators of the Nazi war crimes, established ten principles of ethical conduct in medical research in 1949. Foremost among them was the need for voluntary consent of the human subject and that the experiment be conducted to avoid all unnecessary physical and mental suffering. Notwithstanding all these important efforts and impressive achievements in understanding the ethical failings of Nazi physicians, the bioethical community has almost completely ignored the moral challenges facing the victims of the atrocities. These dilemmas and their responses have continued relevance for modern medicine.

  12. Cooperation between medicine and sociology in head and neck oncology.

    PubMed

    Babin, Emmanuel; Grandazzi, Guillaume

    2014-05-01

    Twenty-first-century medicine is facing many challenges--knowledge and command of technical advances, research development, team management, knowledge transmission, and adaptation to economic constraints--without neglecting "human" aspects, via transformed carer-patient relationships, social change, and so on. The "modern" physicians know that simply treating disease is no longer enough. One of their essential missions lies in offering the individual patient overall care, which implies acknowledging the latter as an individual within a family, social, and professional environment. Indeed, medical practice requires pluridimensional knowledge of the patients' experience of their disease. Yet the contribution sociology can offer to health care remains largely unknown to many physicians, and medical training includes only limited instruction in the human sciences. On the basis of a few observations taken from sociological research, we would like to demonstrate how, in head and neck oncology, interdisciplinary collaboration between medicine and sociology can prove propitious to improving patient care and attention to their close relations.

  13. Discovering modes of action for therapeutic compounds using a genome-wide screen of yeast heterozygotes.

    PubMed

    Lum, Pek Yee; Armour, Christopher D; Stepaniants, Sergey B; Cavet, Guy; Wolf, Maria K; Butler, J Scott; Hinshaw, Jerald C; Garnier, Philippe; Prestwich, Glenn D; Leonardson, Amy; Garrett-Engele, Philip; Rush, Christopher M; Bard, Martin; Schimmack, Greg; Phillips, John W; Roberts, Christopher J; Shoemaker, Daniel D

    2004-01-09

    Modern medicine faces the challenge of developing safer and more effective therapies to treat human diseases. Many drugs currently in use were discovered without knowledge of their underlying molecular mechanisms. Understanding their biological targets and modes of action will be essential to design improved second-generation compounds. Here, we describe the use of a genome-wide pool of tagged heterozygotes to assess the cellular effects of 78 compounds in Saccharomyces cerevisiae. Specifically, lanosterol synthase in the sterol biosynthetic pathway was identified as a target of the antianginal drug molsidomine, which may explain its cholesterol-lowering effects. Further, the rRNA processing exosome was identified as a potential target of the cell growth inhibitor 5-fluorouracil. This genome-wide screen validated previously characterized targets or helped identify potentially new modes of action for over half of the compounds tested, providing proof of this principle for analyzing the modes of action of clinically relevant compounds.

  14. The history of stress hyperglycaemia.

    PubMed

    Balasanthiran, A; Shotliff, K

    2015-01-01

    Stress hyperglycaemia, is a common phenomenon, frequently associated with adverse outcomes in a number of prevalent conditions including myocardial infarction and stroke. Knowledge on stress hyperglycaemia evolved in tandem with knowledge relating to homeostasis, stress and disease and involved some of the world's most eminent thinkers. Despite this, it still remains under-recognised. This paper illustrates significant points in the history of stress hyperglycaemia, from antiquity through to the present day, as well as the challenges faced in translating research into clinical benefit for patients. Profiles of significant protagonists including Claude Bernard, Walter Cannon and Hans Seyle are presented, as well their roles in the emergence of modern-day terminology and pathophysiological models. Major themes such as 'fight or flight' and homeostasis are central to this discussion. Closer to the present day, the role of stress hyperglycaemia in a number of common medical conditions is explored in more detail. Contention around evidence for treatment and the future risk of diabetes mellitus are also discussed.

  15. New scientific challenges - the possibilities of using selenium in poultry nutrition and impact on meat quality

    NASA Astrophysics Data System (ADS)

    Marković, R.; Glišić, M.; Bošković, M.; Baltić, M. Ž.

    2017-09-01

    Physiological stress is one of many concerns facing modern broiler production. In conditions when birds are exposed to stress, supplementation of selenium, which is a crucial glutathione peroxidase enzymatic cofactor, increases the antioxidant capacity of the animals and decreases the harmful effects of free radicals. Dietary selenium improves production performance and health of animals, and positively affects the immune system, the quality, selenium content and fatty acid composition of meat and eggs. There are several different forms of selenium, the most common dietary supplements being an inorganic form (sodium selenite) and anorganic form (selenomethionine). However, in recent years, new forms of selenium, such as a 2-hydroxy-4-methylselenobutanoic acid (HMSeBA) and nanoselenium, which have more bioavailability, bioefficacy, and low toxicity have been designed. In this short comparative overview discusses the effects of inorganic, organic and nanoforms of selenium on production results, glutathione peroxidase activity, meat quality and level of toxicity in poultry.

  16. Pose estimation of industrial objects towards robot operation

    NASA Astrophysics Data System (ADS)

    Niu, Jie; Zhou, Fuqiang; Tan, Haishu; Cao, Yu

    2017-10-01

    With the advantages of wide range, non-contact and high flexibility, the visual estimation technology of target pose has been widely applied in modern industry, robot guidance and other engineering practices. However, due to the influence of complicated industrial environment, outside interference factors, lack of object characteristics, restrictions of camera and other limitations, the visual estimation technology of target pose is still faced with many challenges. Focusing on the above problems, a pose estimation method of the industrial objects is developed based on 3D models of targets. By matching the extracted shape characteristics of objects with the priori 3D model database of targets, the method realizes the recognition of target. Thus a pose estimation of objects can be determined based on the monocular vision measuring model. The experimental results show that this method can be implemented to estimate the position of rigid objects based on poor images information, and provides guiding basis for the operation of the industrial robot.

  17. Measurement Issues in Health Disparities Research

    PubMed Central

    Ramírez, Mildred; Ford, Marvella E; Stewart, Anita L; A Teresi, Jeanne

    2005-01-01

    Background Racial and ethnic disparities in health and health care have been documented; the elimination of such disparities is currently part of a national agenda. In order to meet this national objective, it is necessary that measures identify accurately the true prevalence of the construct of interest across diverse groups. Measurement error might lead to biased results, e.g., estimates of prevalence, magnitude of risks, and differences in mean scores. Addressing measurement issues in the assessment of health status may contribute to a better understanding of health issues in cross-cultural research. Objective To provide a brief overview of issues regarding measurement in diverse populations. Findings Approaches used to assess the magnitude and nature of bias in measures when applied to diverse groups include qualitative analyses, classic psychometric studies, as well as more modern psychometric methods. These approaches should be applied sequentially, and/or iteratively during the development of measures. Conclusions Investigators performing comparative studies face the challenge of addressing measurement equivalence, crucial for obtaining accurate results in cross-cultural comparisons. PMID:16179000

  18. The application of exergy to human-designed systems

    NASA Astrophysics Data System (ADS)

    Hamilton, P.

    2012-12-01

    Exergy is the portion of the total energy of a system that is available for conversion to useful work. Exergy takes into account both the quantity and quality of energy. Heat is the inevitable product of using any form of high-quality energy such as electricity. Modern commercial buildings and industrial facilities use large amounts of electricity and so produce huge amounts of heat. This heat energy typically is treated as a waste product and discharged to the environment and then high-quality energy sources are consumed to satisfy low-quality energy heating and cooling needs. Tens of thousands of buildings and even whole communities could meet much of their heating and cooling needs through the capture and reuse of heat energy. Yet the application of exergy principles often faces resistance because it challenges conventions about how we design, construct and operate human-engineered systems. This session will review several exergy case studies and conclude with an audience discussion of how exergy principles may be both applied and highlighted in formal and informal education settings.

  19. Neolithic dairy farming at the extreme of agriculture in northern Europe

    PubMed Central

    Cramp, Lucy J. E.; Evershed, Richard P.; Lavento, Mika; Halinen, Petri; Mannermaa, Kristiina; Oinonen, Markku; Kettunen, Johannes; Perola, Markus; Onkamo, Päivi; Heyd, Volker

    2014-01-01

    The conventional ‘Neolithic package’ comprised animals and plants originally domesticated in the Near East. As farming spread on a generally northwest trajectory across Europe, early pastoralists would have been faced with the challenge of making farming viable in regions in which the organisms were poorly adapted to providing optimal yields or even surviving. Hence, it has long been debated whether Neolithic economies were ever established at the modern limits of agriculture. Here, we examine food residues in pottery, testing a hypothesis that Neolithic farming was practiced beyond the 60th parallel north. Our findings, based on diagnostic biomarker lipids and δ13C values of preserved fatty acids, reveal a transition at ca 2500 BC from the exploitation of aquatic organisms to processing of ruminant products, specifically milk, confirming farming was practiced at high latitudes. Combining this with genetic, environmental and archaeological information, we demonstrate the origins of dairying probably accompanied an incoming, genetically distinct, population successfully establishing this new subsistence ‘package’. PMID:25080345

  20. Genetic technologies and ethics.

    PubMed

    Ardekani, Ali M

    2009-01-01

    In the past decade, the human genome has been completely sequenced and the knowledge from it has begun to influence the fields of biological and social sciences in fundamental ways. Identification of about 25000 genes in the human genome is expected to create great benefits in diagnosis and treatment of diseases in the coming years. However, Genetic technologies have also created many interesting and difficult ethical issues which can affect the human societies now and in the future. Application of genetic technologies in the areas of stem cells, cloning, gene therapy, genetic manipulation, gene selection, sex selection and preimplantation diagnosis has created a great potential for the human race to influence and change human life on earth as we know it today. Therefore, it is important for leaders of societies in the modern world to pay attention to the advances in genetic technologies and prepare themselves and those institutions under their command to face the challenges which these new technologies induce in the areas of ethics, law and social policies.

  1. Designing the modern pump: engineering aspects of continuous subcutaneous insulin infusion software.

    PubMed

    Welsh, John B; Vargas, Steven; Williams, Gary; Moberg, Sheldon

    2010-06-01

    Insulin delivery systems attracted the efforts of biological, mechanical, electrical, and software engineers well before they were commercially viable. The introduction of the first commercial insulin pump in 1983 represents an enduring milestone in the history of diabetes management. Since then, pumps have become much more than motorized syringes and have assumed a central role in diabetes management by housing data on insulin delivery and glucose readings, assisting in bolus estimation, and interfacing smoothly with humans and compatible devices. Ensuring the integrity of the embedded software that controls these devices is critical to patient safety and regulatory compliance. As pumps and related devices evolve, software engineers will face challenges and opportunities in designing pumps that are safe, reliable, and feature-rich. The pumps and related systems must also satisfy end users, healthcare providers, and regulatory authorities. In particular, pumps that are combined with glucose sensors and appropriate algorithms will provide the basis for increasingly safe and precise automated insulin delivery-essential steps to developing a fully closed-loop system.

  2. Red, White and Black: Colors of Beauty, Tints of Health and Cosmetic Materials in Early Modern English Art Writing.

    PubMed

    Sammern, Romana

    2015-01-01

    Alongside Richard Haydocke's translation of Giovanni Paolo Lomazzo's treatise on painting (1598), the article examines concepts of color concerning cosmetics, painting and complexion as they relate to aesthetics, artistic and medical practice in the sixteenth and seventeenth centuries. Beginning with white and red as ideal colors of beauty in Agnolo Firenzuola's Discourse on the beauty of women (1541), the essay places color in relation to major issues in art, medicine and empiricism by discussing beauty as a quality of humoral theory and its colors as visual results of physiological processes. Challenging the relation of art and nature, gender and production, Lomazzo's account of complexion and Haydocke's additions on cosmetic practices and face-painting provide key passages that shed light on the relation of cosmetics colors, art writing and artistic practices at the convergence of the body, art and medicine in the context of the emerging English virtuosi around 1600.

  3. Readiness Assessment Towards Smart Manufacturing System for Tuna Processing Industry in Indonesia

    NASA Astrophysics Data System (ADS)

    Anggrahini, D.; Kurniati, N.; Karningsih, P. D.; Parenreng, S. M.; Syahroni, N.

    2018-04-01

    Marine product processing is one of the top priority clusters in the national development. Tuna, as a kind of deep ocean fishes, has the highest number of production that significantly increased throughout the years. Indonesia government encourages tuna processing industry, which are mostly dominated by small to medium enterprises, to grow continuously. Nowadays, manufacturers are facing substantial challenges in adopting modern system and technology that will lead a significant improvement through the internet of things (IoT). A smart factory transform integrated manufacturing process, in a high speed processing to respond customer needs. It has some positive impacts, such as increasing productivity, reducing set up time, shortening marketing and other support activities, hence the process is being more flexible and efficient. To implement smart manufacturing system, factories should know the readiness at any level of them, technology capability and strategy appropriateness. This exploratory study aims to identify the criterias, and develop an assessment tools to measure the level towards smart factory.

  4. Multi-Time Step Service Restoration for Advanced Distribution Systems and Microgrids

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Chen, Bo; Chen, Chen; Wang, Jianhui

    Modern power systems are facing increased risk of disasters that can cause extended outages. The presence of remote control switches (RCSs), distributed generators (DGs), and energy storage systems (ESS) provides both challenges and opportunities for developing post-fault service restoration methodologies. Inter-temporal constraints of DGs, ESS, and loads under cold load pickup (CLPU) conditions impose extra complexity on problem formulation and solution. In this paper, a multi-time step service restoration methodology is proposed to optimally generate a sequence of control actions for controllable switches, ESSs, and dispatchable DGs to assist the system operator with decision making. The restoration sequence is determinedmore » to minimize the unserved customers by energizing the system step by step without violating operational constraints at each time step. The proposed methodology is formulated as a mixed-integer linear programming (MILP) model and can adapt to various operation conditions. Furthermore, the proposed method is validated through several case studies that are performed on modified IEEE 13-node and IEEE 123-node test feeders.« less

  5. Web-Based vs. Face-to-Face MBA Classes: A Comparative Assessment Study

    ERIC Educational Resources Information Center

    Brownstein, Barry; Brownstein, Deborah; Gerlowski, Daniel A.

    2008-01-01

    The challenges of online learning include ensuring that the learning outcomes are at least as robust as in the face-to-face sections of the same course. At the University of Baltimore, both online sections and face-to-face sections of core MBA courses are offered. Once admitted to the MBA, students are free to enroll in any combination of…

  6. Using obsidian transfer distances to explore social network maintenance in late Pleistocene hunter-gatherers.

    PubMed

    Pearce, Eiluned; Moutsiou, Theodora

    2014-12-01

    Social behaviour is notoriously difficult to study archaeologically and it is unclear how large the networks of prehistoric humans were, or how they remained connected. Maintaining social cohesion was crucial for early humans because social networks facilitate cooperation and are imperative for survival and reproduction. Recent hunter-gatherer social organisation typically comprises a number of nested layers, ranging from the nuclear family through to the ~1500-strong ethnolinguistic tribe. Here we compare maximum obsidian transfer distances from the late Pleistocene with ethnographic data on the size of the geographic areas associated with each of these social grouping layers in recent hunter-gatherers. The closest match between the two is taken to indicate the maximum social layer within which contact could be sustained by Pleistocene hominins. Within both the (sub)tropical African and Subarctic biomes, the maximum obsidian transfer distances for Pleistocene modern humans (~200km and ~400km respectively) correspond to the geographic ranges of the outermost tribal layer in recent hunter-gatherers. This suggests that modern humans could potentially sustain the cohesion of their entire tribe at all latitudes, even though networks are more dispersed nearer the poles. Neanderthal obsidian transfer distances (300km) indicate that although Neanderthal home ranges are larger than those of low latitude hominins, Neanderthals travelled shorter distances than modern humans living at the same high latitudes. We argue that, like modern humans, Neanderthals could have maintained tribal cohesion, but that their tribes were substantially smaller than those of contemporary modern humans living in similar environments. The greater time taken to traverse the larger modern human tribal ranges may have limited the frequency of their face-to-face interactions and thus necessitated additional mechanisms to ensure network connectivity, such as the exchange of symbolic artefacts including ornaments and figurines. Such cultural supports may not have been required to the same extent by the Neanderthals due to their smaller tribes and home ranges.

  7. Using obsidian transfer distances to explore social network maintenance in late Pleistocene hunter-gatherers

    PubMed Central

    Pearce, Eiluned; Moutsiou, Theodora

    2014-01-01

    Social behaviour is notoriously difficult to study archaeologically and it is unclear how large the networks of prehistoric humans were, or how they remained connected. Maintaining social cohesion was crucial for early humans because social networks facilitate cooperation and are imperative for survival and reproduction. Recent hunter-gatherer social organisation typically comprises a number of nested layers, ranging from the nuclear family through to the ~1500-strong ethnolinguistic tribe. Here we compare maximum obsidian transfer distances from the late Pleistocene with ethnographic data on the size of the geographic areas associated with each of these social grouping layers in recent hunter-gatherers. The closest match between the two is taken to indicate the maximum social layer within which contact could be sustained by Pleistocene hominins. Within both the (sub)tropical African and Subarctic biomes, the maximum obsidian transfer distances for Pleistocene modern humans (~200km and ~400km respectively) correspond to the geographic ranges of the outermost tribal layer in recent hunter-gatherers. This suggests that modern humans could potentially sustain the cohesion of their entire tribe at all latitudes, even though networks are more dispersed nearer the poles. Neanderthal obsidian transfer distances (300km) indicate that although Neanderthal home ranges are larger than those of low latitude hominins, Neanderthals travelled shorter distances than modern humans living at the same high latitudes. We argue that, like modern humans, Neanderthals could have maintained tribal cohesion, but that their tribes were substantially smaller than those of contemporary modern humans living in similar environments. The greater time taken to traverse the larger modern human tribal ranges may have limited the frequency of their face-to-face interactions and thus necessitated additional mechanisms to ensure network connectivity, such as the exchange of symbolic artefacts including ornaments and figurines. Such cultural supports may not have been required to the same extent by the Neanderthals due to their smaller tribes and home ranges. PMID:25214705

  8. Developmental Idealism and Cultural Models of the Family in Malawi

    PubMed Central

    Pierotti, Rachael S.; Young-DeMarco, Linda; Watkins, Susan

    2014-01-01

    This paper examines the extent to which developmental idealism has been disseminated in Malawi. Developmental idealism is a set of beliefs and values about development and the relationships between development and family structures and behavior. Developmental idealism states that attributes of societies and families defined as modern are better than attributes defined as traditional, that modern societies help produce modern families, that modern families facilitate the achievement of modern societies, and that the future will bring family change in the direction of modernity. Previous research has demonstrated that knowledge of developmental idealism is widespread in many places around the world, but provides little systematic data about it in sub-Saharan Africa or how knowledge of it is associated with certain demographic characteristics in that region. In this paper, we address this issue by examining whether ordinary people in two settings in Malawi, a sub-Saharan African country, have received and understood messages that are intended to associate development with certain types of family forms and family behaviors. We then examine associations between demographic characteristics and developmental idealism to investigate possible mechanisms linking global discourse about development to the grassroots. We analyze data collected in face-to-face surveys from two samples of Malawian men in 2009 and 2010, one rural, the other in a low-to-medium income neighborhood of a city. Our analysis of these survey data shows considerable evidence that many developmental idealism beliefs have been spread in that country and that education has positive effects on beliefs in the association between development and family attributes. We also find higher levels of developmental idealism awareness in the urban sample than we do in the rural sample, but once dissimilarities in education and wealth between the two samples are controlled, awareness levels no longer differed between urban and rural respondents. We explore how these beliefs intersect with longstanding local values and beliefs in Malawi. PMID:25197155

  9. The Challenge of Access in Indian Higher Education.

    ERIC Educational Resources Information Center

    Chitnis, Suma

    2000-01-01

    With an ancient tradition of educational exclusion, modern India has set democratic goals for educational access and quality, though discrimination still challenges public policy goals. Highlights: Buddhism's ancient challenges to exclusion; early declines of education; missionary education; colonial higher education; distance from the lives of…

  10. Panel Discussion

    NASA Astrophysics Data System (ADS)

    Langer, James

    1997-03-01

    Panelists: Arthur Bienenstock, Stanford University Cherry Ann Murray, Lucent Technologies Venkatesh Narayanamurti, University of California-Santa Barbara Paul Peercy, SEMI-SEMATECH Robert Richardson, Cornell University James Roberto, Oak Ridge National Laboratory The Board on Physics and Astronomy is undertaking a series of reassessments of all branches of physics as the foundation of a new physics survey. As part of this project, a Committee on Condensed Matter and Materials Physics has been established under the leadership of Venkatesh Narayanamurti of the University of California-Santa Barbara. The committee has been working since June on a study that will include an illustrative recounting of major recent achievements; identification of new opportunities and challenges facing the field; and articulation-for leaders in government, industry, universities, and the public at large-of the important roles played by the field in modern society. An especially urgent issue is how to maintain the intellectual vitality of condensed matter and materials physics, and its contributions to the well-being of the United States, in an era of limited resources. The forum will feature a panel of materials researchers who are members of the Committee on Condensed Matter and Materials Physics. They will give a brief report on the status of the study and engage in a dialogue with the audience about issues facing the condensed matter and materials physics community. Broad community input is vital to the success of the study. Please come and make your voice heard!

  11. A successful experience of the Iranian blood transfusion organization in improving accessibility and affordability of plasma derived medicine.

    PubMed

    Chegini, Azita; Torab, Seyed Ardeshir; Pourfatollah, Ali Akbar

    2017-02-01

    Plasma is the liquid part of blood. It is estimated 21.6 million liters of plasma collect from Whole blood annually. From these plasma, 4.2 million liters transfuse, 8.1 million liters fractionate, 9.3 million liters waste. Nowadays, blood products and PDM (plasma derived medicine) consider as essential medicine in modern health care and transfusion medicine. Iranian blood transfusion organization as a non-profit organization was established in 1974 in order to centralize all blood transfusion activities from donor recruitment to distribution of blood components to hospitals. Iran is the only country in EMR region with the rate of 20-29.9 blood donations per 1000 population and reached 100% voluntary non-remunerated blood donation in 2007. RBCs and platelets demand are much more than FFPs so the IBTO was faced the surplus plasma that could cause surplus plasma wastage. Simultaneously, hospitals need more plasma derived medicine especially albumin, IVIG, factor VIII, factor IX. IBTO was faced the challenges such as Fractionators selection, Plasma volume shipment, Contract duration, Product profile, Multiple External audits, Cold chain maintenance, Transporting plasma across international borders, NAT test. To overcome plasma wastage and storage of PDM. IBTO involved toll manufacturing in 2005 and not only prevents plasma wastage but also save MOH (ministry of health) budget. Copyright © 2016. Published by Elsevier Ltd.

  12. Using artificial neural network and satellite data to predict rice yield in Bangladesh

    NASA Astrophysics Data System (ADS)

    Akhand, Kawsar; Nizamuddin, Mohammad; Roytman, Leonid; Kogan, Felix; Goldberg, Mitch

    2015-09-01

    Rice production in Bangladesh is a crucial part of the national economy and providing about 70 percent of an average citizen's total calorie intake. The demand for rice is constantly rising as the new populations are added in every year in Bangladesh. Due to the increase in population, the cultivation land decreases. In addition, Bangladesh is faced with production constraints such as drought, flooding, salinity, lack of irrigation facilities and lack of modern technology. To maintain self sufficiency in rice, Bangladesh will have to continue to expand rice production by increasing yield at a rate that is at least equal to the population growth until the demand of rice has stabilized. Accurate rice yield prediction is one of the most important challenges in managing supply and demand of rice as well as decision making processes. Artificial Neural Network (ANN) is used to construct a model to predict Aus rice yield in Bangladesh. Advanced Very High Resolution Radiometer (AVHRR)-based remote sensing satellite data vegetation health (VH) indices (Vegetation Condition Index (VCI) and Temperature Condition Index (TCI) are used as input variables and official statistics of Aus rice yield is used as target variable for ANN prediction model. The result obtained with ANN method is encouraging and the error of prediction is less than 10%. Therefore, prediction can play an important role in planning and storing of sufficient rice to face in any future uncertainty.

  13. Engineering Students: Enhancing Employability Skills through PBL

    NASA Astrophysics Data System (ADS)

    H, Othman; Mat Daud K., A.; U, Ewon; Salleh B, Mohd; Omar N., H.; Baser J, Abd; Ismail M., E.; A, Sulaiman

    2017-05-01

    As a developing country, Malaysia faces challenging tasks to develop her economy just like many other countries. Nowadays, change involves many aspects like the economy from agriculture to manufacturing, technology from modern to more advanced ones; mindset from traditional to advanced and so on. Previous studies show that one of the major issues facing local graduates is the lack of employability skills. This problem concerns not only the government but undergraduates and institutions alike. From the pedagogical aspect, one of the more effective ways to improve this is through instructional delivery and in this case the use of Problem-based Learning (PBL). The need to adopt PBL should involved applied subjects undertaken by engineering students. Studies have shown that the use of PBL has been proven to make learning more attractive and effective. In this research, we studied the effectiveness of PBL towards enhancing employability skills among engineering undergraduates. This study adopted a combination of qualitative and quantitative approaches. Data was collected using documents analysis. Student samples comprised manufacturing engineering undergraduates from public institutions of higher learning in Malaysia. The results show that student’s employability skills can be enhanced using PBL. In addition, students become more competitive towards making them more relevance with the needs of the industry with regard to employability skills. In conclusion, PBL is a very effective catalyst towards raising the employability skills among engineering undergraduates and should be adopted in all engineering education.

  14. Financial inequality and gender in older people.

    PubMed

    Vlachantoni, Athina

    2012-06-01

    Gender inequalities in the financial resources in later life result from the combined effect of women's atypical life courses, which include interrupted employment records and periods of care provision, and the fact that pension systems have generally been slow in mitigating 'diversions' from continuous and full-time working lives. Gender differentials in financial resources can often result in a greater likelihood of facing poverty for older women compared to older men, and such risk can be experienced for longer periods for women, as a result of their higher life expectancy on average. For example, across the EU-27, 16% of men compared to 23% of women aged 65 and over faced a poverty risk, and at age 65, men can expect to live another 17 years on average, while women another 21 years. Although modern pension systems are increasingly recognising the diversity of women's patterns of paid and unpaid work, for example by accounting for periods of childcare in the calculation of the state pension, research continues to show a 'penalty' for women who have spent significant periods of their life providing care to children or dependent adults in and outside the household. Reducing such penalty is particularly important as population ageing and an increasing demand for formal and informal care are likely to present challenges with critical policy implications for societies and individuals alike. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

  15. Game Face

    ERIC Educational Resources Information Center

    Weiner, Jill

    2005-01-01

    In this article, the author discusses "Game Face: Life Lessons Across the Curriculum", a teaching kit that challenges assumptions and builds confidence. Game Face, which is derived from a book and art exhibition, "Game Face: What Does a Female Athlete Look Like?", uses layered and powerful images of women and girls participating in sports to teach…

  16. Relativity, quantum physics and philosophy in the upper secondary curriculum: challenges, opportunities and proposed approaches

    NASA Astrophysics Data System (ADS)

    Henriksen, Ellen K.; Bungum, Berit; Angell, Carl; Tellefsen, Cathrine W.; Frågåt, Thomas; Vetleseter Bøe, Maria

    2014-11-01

    In this article, we discuss how quantum physics and relativity can be taught in upper secondary school, in ways that promote conceptual understanding and philosophical reflections. We present the ReleQuant project, in which web-based teaching modules have been developed. The modules address competence aims in the Norwegian national curriculum for physics (final year of upper secondary education), which is unique in that it includes general relativity, entangled photons and the epistemological consequences of modern physics. These topics, with their high demands on students’ understanding of abstract and counter-intuitive concepts and principles, are challenging for teachers to teach and for students to learn. However, they also provide opportunities to present modern physics in innovative ways that students may find motivating and relevant both in terms of modern technological applications and in terms of contributions to students’ intellectual development. Beginning with these challenges and opportunities, we briefly present previous research and theoretical perspectives with relevance to student learning and motivation in modern physics. Based on this, we outline the ReleQuant teaching approach, where students use written and oral language and a collaborative exploration of animations and simulations as part of their learning process. Finally, we present some of the first experiences from classroom tests of the quantum physics modules.

  17. Joint sparse learning for 3-D facial expression generation.

    PubMed

    Song, Mingli; Tao, Dacheng; Sun, Shengpeng; Chen, Chun; Bu, Jiajun

    2013-08-01

    3-D facial expression generation, including synthesis and retargeting, has received intensive attentions in recent years, because it is important to produce realistic 3-D faces with specific expressions in modern film production and computer games. In this paper, we present joint sparse learning (JSL) to learn mapping functions and their respective inverses to model the relationship between the high-dimensional 3-D faces (of different expressions and identities) and their corresponding low-dimensional representations. Based on JSL, we can effectively and efficiently generate various expressions of a 3-D face by either synthesizing or retargeting. Furthermore, JSL is able to restore 3-D faces with holes by learning a mapping function between incomplete and intact data. Experimental results on a wide range of 3-D faces demonstrate the effectiveness of the proposed approach by comparing with representative ones in terms of quality, time cost, and robustness.

  18. The Auto

    ERIC Educational Resources Information Center

    Novick, Sheldon

    1976-01-01

    The basic automobile design has persisted for fifty years with innovations only in production and marketing. Complex interrelationships among steel, oil, rubber, road building, and automobile industries perpetuate the "modern Model T's." Efforts to alter design to meet safety and environmental standards face tremendous resistance from a…

  19. African Women in the Visual Arts.

    ERIC Educational Resources Information Center

    Aronson, Lisa

    1991-01-01

    Explores recent studies in anthropology, art history, and archeology on African women's art from a feminist theoretical perspective. Relates women's arts to several sociological and economic factors and suggests new avenues of exploration, especially in the face of urbanization and modernization. (CJS)

  20. Thermal-to-visible face recognition using partial least squares.

    PubMed

    Hu, Shuowen; Choi, Jonghyun; Chan, Alex L; Schwartz, William Robson

    2015-03-01

    Although visible face recognition has been an active area of research for several decades, cross-modal face recognition has only been explored by the biometrics community relatively recently. Thermal-to-visible face recognition is one of the most difficult cross-modal face recognition challenges, because of the difference in phenomenology between the thermal and visible imaging modalities. We address the cross-modal recognition problem using a partial least squares (PLS) regression-based approach consisting of preprocessing, feature extraction, and PLS model building. The preprocessing and feature extraction stages are designed to reduce the modality gap between the thermal and visible facial signatures, and facilitate the subsequent one-vs-all PLS-based model building. We incorporate multi-modal information into the PLS model building stage to enhance cross-modal recognition. The performance of the proposed recognition algorithm is evaluated on three challenging datasets containing visible and thermal imagery acquired under different experimental scenarios: time-lapse, physical tasks, mental tasks, and subject-to-camera range. These scenarios represent difficult challenges relevant to real-world applications. We demonstrate that the proposed method performs robustly for the examined scenarios.

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