MWPC prototyping and performance test for the STAR inner TPC upgrade

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shen, Fuwang; Wang, Shuai; Kong, Fangang

A new prototype of STAR inner Time Projection Chamber (iTPC) MWPC sector has been fabricated and tested in an X-ray test system. The wire chamber built at Shandong University has a wire tension precision better than 6% and wire pitch precision better than 10 μm. The gas gain uniformity and energy resolution are measured to be better than 1% (RMS) and 20% (FWHM), respectively, using an 55Fe X-ray source. The iTPC upgrade project is to replace all 24 STAR TPC inner sectors as a crucial detector upgrade for the RHIC beam energy scan phase II program. Furthermore, the test resultsmore » show that the constructed iTPC prototype meets all project requirements.« less

The GlueX central drift chamber: Design and performance

DOE Office of Scientific and Technical Information (OSTI.GOV)

Van Haarlem, Y; Barbosa, F; Dey, B

2010-10-01

Tests and studies concerning the design and performance of the GlueX Central Drift Chamber (CDC) are presented. A full-scale prototype was built to test and steer the mechanical and electronic design. Small scale prototypes were constructed to test for sagging and to do timing and resolution studies of the detector. These studies were used to choose the gas mixture and to program a Monte Carlo simulation that can predict the detector response in an external magnetic field. Particle identification and charge division possibilities were also investigated.

Polarity effects and apparent ion recombination in microionization chambers

DOE Office of Scientific and Technical Information (OSTI.GOV)

Miller, Jessica R., E-mail: miller@humonc.wisc.edu; Hooten, Brian D.; Micka, John A.

Purpose: Microchambers demonstrate anomalous voltage-dependent polarity effects. Existing polarity and ion recombination correction factors do not account for these effects. As a result, many commercial microchamber models do not meet the specification of a reference-class ionization chamber as defined by the American Association of Physicists in Medicine. The purpose of this investigation is to determine the cause of these voltage-dependent polarity effects. Methods: A series of microchamber prototypes were produced to isolate the source of the voltage-dependent polarity effects. Parameters including ionization-chamber collecting-volume size, stem and cable irradiation, chamber assembly, contaminants, high-Z materials, and individual chamber components were investigated. Measurementsmore » were performed with electrodes coated with graphite to isolate electrode conductivity. Chamber response was measured as the potential bias of the guard electrode was altered with respect to the collecting electrode, through the integration of additional power supplies. Ionization chamber models were also simulated using COMSOL Multiphysics software to investigate the effect of a potential difference between electrodes on electric field lines and collecting volume definition. Results: Investigations with microchamber prototypes demonstrated that the significant source of the voltage-dependent polarity effects was a potential difference between the guard and collecting electrodes of the chambers. The voltage-dependent polarity effects for each prototype were primarily isolated to either the guard or collecting electrode. Polarity effects were reduced by coating the isolated electrode with a conductive layer of graphite. Polarity effects were increased by introducing a potential difference between the electrodes. COMSOL simulations further demonstrated that for a given potential difference between electrodes, the collecting volume of the chamber changed as the applied voltage was altered, producing voltage-dependent polarity effects in the chamber response. Ionization chamber measurements and COMSOL simulations demonstrated an inverse relationship between the chamber collecting volume size and the severity of voltage-dependent polarity effects on chamber response. The effect of a given potential difference on chamber polarity effects was roughly ten times greater for microchambers as compared to Farmer-type chambers. Stem and cable irradiations, chamber assembly, contaminants, and high-Z materials were not found to be a significant source of the voltage-dependent polarity effects. Conclusions: A potential difference between the guard and collecting electrodes was found to be the primary source of the voltage-dependent polarity effects demonstrated by microchambers. For a given potential difference between electrodes, the relative change in the collecting volume is smaller for larger-volume chambers, illustrating why these polarity effects are not seen in larger-volume chambers with similar guard and collecting electrode designs. Thus, for small-volume chambers, it is necessary to reduce the potential difference between the guard and collecting electrodes in order to reduce polarity effects for reference dosimetry measurements.« less

A Front-End Electronics Prototype Based on Gigabit Ethernet for the ATLAS Small-Strip Thin Gap Chamber

NASA Astrophysics Data System (ADS)

Hu, Kun; Lu, Houbing; Wang, Xu; Li, Feng; Wang, Xinxin; Geng, Tianru; Yang, Hang; Liu, Shengquan; Han, Liang; Jin, Ge

2017-06-01

A front-end electronics prototype for the ATLAS small-strip Thin Gap Chamber (sTGC) based on gigabit Ethernet has been developed. The prototype is designed to read out signals of pads, wires, and strips of the sTGC detector. The prototype includes two VMM2 chips developed to read out the signals of the sTGC, a Xilinx Kintex-7 field-programmable gate array (FPGA) used for the VMM2 configuration and the events storage, and a gigabit Ethernet transceiver PHY chip for interfacing with a computer. The VMM2 chip is designed for the readout of the Micromegas detector and sTGC detector, which is composed of 64 linear front-end channels. Each channel integrates a charge-sensitive amplifier, a shaper, several analog-to-digital converters, and other digital functions. For a bunch-crossing interval of 25 ns, events are continuously read out by the FPGA and forwarded to the computer. The interface between the computer and the prototype has been measured to reach an error-free rate of 900 Mb/s, therefore making a very effective use of the available bandwidth. Additionally, the computer can control several prototypes of this kind simultaneously via the Ethernet interface. At present, the prototype will be used for the sTGC performance test. The features of the prototype are described in detail.

Joint measurement of the atmospheric muon flux through the Puy de Dôme volcano with plastic scintillators and Resistive Plate Chambers detectors

NASA Astrophysics Data System (ADS)

Ambrosino, F.; Anastasio, A.; Bross, A.; Béné, S.; Boivin, P.; Bonechi, L.; Cârloganu, C.; Ciaranfi, R.; Cimmino, L.; Combaret, Ch.; D'Alessandro, R.; Durand, S.; Fehr, F.; Français, V.; Garufi, F.; Gailler, L.; Labazuy, Ph.; Laktineh, I.; Lénat, J.-F.; Masone, V.; Miallier, D.; Mirabito, L.; Morel, L.; Mori, N.; Niess, V.; Noli, P.; Pla-Dalmau, A.; Portal, A.; Rubinov, P.; Saracino, G.; Scarlini, E.; Strolin, P.; Vulpescu, B.

2015-11-01

The muographic imaging of volcanoes relies on the measured transmittance of the atmospheric muon flux through the target. An important bias affecting the result comes from background contamination mimicking a higher transmittance. The MU-RAY and TOMUVOL collaborations measured independently in 2013 the atmospheric muon flux transmitted through the Puy de Dôme volcano using their early prototype detectors, based on plastic scintillators and on Glass Resistive Plate Chambers, respectively. These detectors had three (MU-RAY) or four (TOMUVOL) detection layers of 1 m2 each, tens (MU-RAY) or hundreds (TOMUVOL) of nanosecond time resolution, a few millimeter position resolution, an energy threshold of few hundreds MeV, and no particle identification capabilities. The prototypes were deployed about 1.3 km away from the summit, where they measured, behind rock depths larger than 1000 m, remnant fluxes of 1.83±0.50(syst)±0.07(stat) m-2 d-1 deg-2 (MU-RAY) and 1.95±0.16(syst)±0.05(stat) m-2 d-1 deg-2 (TOMUVOL), that roughly correspond to the expected flux of high-energy atmospheric muons crossing 600 meters water equivalent (mwe) at 18° elevation. This implies that imaging depths larger than 500 mwe from 1 km away using such prototype detectors suffer from an overwhelming background. These measurements confirm that a new generation of detectors with higher momentum threshold, time-of-flight measurement, and/or particle identification is needed. The MU-RAY and TOMUVOL collaborations expect shortly to operate improved detectors, suitable for a robust muographic imaging of kilometer-scale volcanoes.

Joint measurement of the atmospheric muon flux through the Puy de Dome volcano with plastic scintillators and Resistive Plate Chambers detectors

DOE PAGES

Ambrosino, F.; Anastasio, A.; Bross, A.; ...

2015-11-14

The muographic imaging of volcanoes relies on the measured transmittance of the atmospheric muon flux through the target. An important bias affecting the result comes from background contamination mimicking a higher transmittance. The MU-RAY and TOMUVOL collaborations measured independently in 2013 the atmospheric muon flux transmitted through the Puy de Dôme volcano using their early prototype detectors, based on plastic scintillators and on Glass Resistive Plate Chambers, respectively. These detectors had three (MU-RAY) or four (TOMUVOL) detection layers of 1 m 2 each, tens (MU-RAY) or hundreds (TOMUVOL) of nanosecond time resolution, a few millimeter position resolution, an energy thresholdmore » of few hundreds MeV, and no particle identification capabilities. The prototypes were deployed about 1.3 km away from the summit, where they measured, behind rock depths larger than 1000 m, remnant fluxes of 1.83±0.50(syst)±0.07(stat) m –2 d –1 deg –2 (MU-RAY) and 1.95±0.16(syst)±0.05(stat) m –2 d –1 deg –2 (TOMUVOL), that roughly correspond to the expected flux of high-energy atmospheric muons crossing 600 meters water equivalent (mwe) at 18° elevation. This implies that imaging depths larger than 500 mwe from 1 km away using such prototype detectors suffer from an overwhelming background. These measurements confirm that a new generation of detectors with higher momentum threshold, time-of-flight measurement, and/or particle identification is needed. As a result, the MU-RAY and TOMUVOL collaborations expect shortly to operate improved detectors, suitable for a robust muographic imaging of kilometer-scale volcanoes.« less

Joint measurement of the atmospheric muon flux through the Puy de Dome volcano with plastic scintillators and Resistive Plate Chambers detectors

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ambrosino, F.; Anastasio, A.; Bross, A.

The muographic imaging of volcanoes relies on the measured transmittance of the atmospheric muon flux through the target. An important bias affecting the result comes from background contamination mimicking a higher transmittance. The MU-RAY and TOMUVOL collaborations measured independently in 2013 the atmospheric muon flux transmitted through the Puy de Dôme volcano using their early prototype detectors, based on plastic scintillators and on Glass Resistive Plate Chambers, respectively. These detectors had three (MU-RAY) or four (TOMUVOL) detection layers of 1 m 2 each, tens (MU-RAY) or hundreds (TOMUVOL) of nanosecond time resolution, a few millimeter position resolution, an energy thresholdmore » of few hundreds MeV, and no particle identification capabilities. The prototypes were deployed about 1.3 km away from the summit, where they measured, behind rock depths larger than 1000 m, remnant fluxes of 1.83±0.50(syst)±0.07(stat) m –2 d –1 deg –2 (MU-RAY) and 1.95±0.16(syst)±0.05(stat) m –2 d –1 deg –2 (TOMUVOL), that roughly correspond to the expected flux of high-energy atmospheric muons crossing 600 meters water equivalent (mwe) at 18° elevation. This implies that imaging depths larger than 500 mwe from 1 km away using such prototype detectors suffer from an overwhelming background. These measurements confirm that a new generation of detectors with higher momentum threshold, time-of-flight measurement, and/or particle identification is needed. As a result, the MU-RAY and TOMUVOL collaborations expect shortly to operate improved detectors, suitable for a robust muographic imaging of kilometer-scale volcanoes.« less

INTERIOR VIEW SHOWING PROTOTYPE BEGUN APRIL 1988 METHOD OF CUTTING ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

INTERIOR VIEW SHOWING PROTOTYPE BEGUN APRIL 1988 METHOD OF CUTTING GLASS, "PERFECT TIN? MACHINE." MANUFACTURED IN DALLAS, TEXAS AND USED FOR CUTTING GLASS WITH A FINISHED EDGE. - Chambers-McKee Window Glass Company, Cutting House, Clay Avenue Extension, Jeannette, Westmoreland County, PA

Environmental qualification testing of the prototype pool boiling experiment

NASA Technical Reports Server (NTRS)

Sexton, J. Andrew

1992-01-01

The prototype Pool Boiling Experiment (PBE) flew on the STS-47 mission in September 1992. This report describes the purpose of the experiment and the environmental qualification testing program that was used to prove the integrity of the prototype hardware. Component and box level vibration and thermal cycling tests were performed to give an early level of confidence in the hardware designs. At the system level, vibration, thermal extreme soaks, and thermal vacuum cycling tests were performed to qualify the complete design for the expected shuttle environment. The system level vibration testing included three axis sine sweeps and random inputs. The system level hot and cold soak tests demonstrated the hardware's capability to operate over a wide range of temperatures and gave the project team a wider latitude in determining which shuttle thermal altitudes were compatible with the experiment. The system level thermal vacuum cycling tests demonstrated the hardware's capability to operate in a convection free environment. A unique environmental chamber was designed and fabricated by the PBE team and allowed most of the environmental testing to be performed within the project's laboratory. The completion of the test program gave the project team high confidence in the hardware's ability to function as designed during flight.

Design of a prototype tri-electrode ion-chamber for megavoltage X-ray imaging

NASA Astrophysics Data System (ADS)

Samant, Sanjiv S.; Gopal, Arun; Jain, Jinesh; Xia, Junyi; DiBianca, Frank A.

2007-04-01

High-energy (megavoltage) X-ray imaging is widely used in industry (e.g., aerospace, construction, material sciences) as well as in health care (radiation therapy). One of the fundamental problems with megavoltage imaging is poor contrast and spatial resolution in the detected images due to the dominance of Compton scattering at megavoltage X-ray energies. Therefore, although megavoltage X-rays can be used to image highly attenuating objects that cannot be imaged at kilovoltage energies, the former does not provide the high image quality that is associated with the latter. A high contrast and spatial resolution detector for high-energy X-ray fields called the kinestatic charge detector (KCD) is presented here. The KCD is a tri-electrode ion-chamber based on highly pressurized noble gas. The KCD operates in conjunction with a strip-collimated X-ray beam (for high scatter rejection) to scan across the imaging field. Its thick detector design and unique operating principle provides enhanced charge signal integration for high quality imaging (quantum efficiency ˜50%) despite the unfavorable implications of high-energy X-ray interactions on image quality. The proposed design for a large-field prototype KCD includes a cylindrical pressure chamber along with 576 signal-collecting electrodes capable of resolving at 2 mm -1. The collecting electrodes are routed out of the chamber through the flat end-cap, thereby optimizing the mechanical strength of the chamber. This article highlights the simplified design of the chamber using minimal components for simple assembly. In addition, fundamental imaging measurements and estimates of ion recombination that were performed on a proof-of-principle test chamber are presented. The imaging performance of the prototype KCD was found to be an order-of-magnitude greater than commercial phosphor screen based flat-panel systems, demonstrating the potential for high-quality megavoltage imaging for a variety of industrial applications.

Development of a High Resolution Liquid Xenon Imaging Telescope for Medium Energy Gamma Ray Astrophysics

NASA Technical Reports Server (NTRS)

Aprile, Elena

1992-01-01

In the third year of the research project, we have (1) tested a 3.5 liter prototype of the Liquid Xenon Time Projection Chamber, (2) used a prototype having a 4.4 cm drift gap to study the charge and energy resolution response of the 3.5 liter chamber, (3) obtained an energy resolution as good as that previously measured by us using chambers with drift gaps of the order of millimeters, (4) observed the induction signals produced by MeV gamma rays, (4) used the 20 hybrid charge sensitive preamplifiers for a nondestructive readout of the electron image on the induction wires, (5) performed extensive Monte Carlo simulations to obtain results on efficiency, background rejection capability, and source flux sensitivity, and (6) developed a reconstruction algorithm for events with multiple interaction points.

Evaluation of the physiological protective efficiency of a new prototype disposable passenger oxygen mask.

DOT National Transportation Integrated Search

1966-04-01

A prototype of a new design disposable passenger mask applicable for emergency use in jet transports at altitudes to 40,000 feet was evaluated. Six subjects instrumented to obtain a variety of physiological information were exposed to a chamber fligh...

Cryogenic and radiation-hard asic for interfacing large format NIR/SWIR detector arrays

NASA Astrophysics Data System (ADS)

Gao, Peng; Dupont, Benoit; Dierickx, Bart; Müller, Eric; Verbruggen, Geert; Gielis, Stijn; Valvekens, Ramses

2017-11-01

For scientific and earth observation space missions, weight and power consumption is usually a critical factor. In order to obtain better vehicle integration, efficiency and controllability for large format NIR/SWIR detector arrays, a prototype ASIC is designed. It performs multiple detector array interfacing, power regulation and data acquisition operations inside the cryogenic chambers. Both operation commands and imaging data are communicated via the SpaceWire interface which will significantly reduce the number of wire goes in and out the cryogenic chamber. This "ASIC" prototype is realized in 0.18um CMOS technology and is designed for radiation hardness.

KiwiSpec: The Design and Performance of a High Resolution Echelle Spectrograph for Astronomy

NASA Astrophysics Data System (ADS)

Gibson, Steven Ross

This document describes the design, analysis, construction and testing of KiwiSpec, a fibre-fed, high resolution astronomical spectrograph of an asymmetric white pupil design. The instrument employs an R4, 31.6 groove mm-1 échelle grating for primary dispersion and a 725 lines mm-1 volume phase holographic (VPH) based grism for cross-dispersion. Two versions of the prototype were designed and constructed: an 'in-air' prototype, and a prototype featuring a vacuum chamber (to increase the stability of the instrument). The KiwiSpec optical design is introduced, as well as a description of the theory behind a cross-dispersed échelle spectrograph. The results of tolerancing the optical design are reported for alignment, optical fabrication, and optical surface quality groups of parameters. The optical windows of an iodine cell are also toleranced. The opto-mechanical mounts of both prototypes are described in detail, as is the design of the vacuum chamber system. Given the goal of 1 m/s radial velocity stability, analyses were undertaken to determine the allowable amount of movement of the vacuum windows, and to determine the allowable changes in temperature and pressure within and outside of the vacuum chamber. The spectral efficiency of the instrument was estimated through a predictive model; this was calculated for the as-built instrument and also for an instrument with ideal, high-efficiency coatings. Measurements of the spectral efficiency of various components of the instrument are reported, as well as a description of the measurement system developed to test the efficiency of VPH gratings. On-sky efficiency measurements from use of KiwiSpec on the 1-m McLellan telescope at Mt John University Observatory are reported. Two possible exposure meter locations are explored via an efficiency model, and also through the measurement of the zero-order reflectivity of the échelle grating. Various stability aspects of the design are investigated. These include the stability of the optical mounts with temperature changes, and also the effect of the expansion and contraction of the supporting optical tables. As well, the stability of the in-air prototype was determined through measurement of the movement of thorium-argon emission lines within spectra as the temperature, atmospheric pressure and relative humidity (naturally) varied. Current and planned testing for determining the stability of the vacuum chamber prototype is discussed.

Deployment and testing of a second prototype expandable surgical chamber in microgravity

NASA Technical Reports Server (NTRS)

Markham, Sanford M.; Rock, John A.

1991-01-01

During microgravity exposure, two separate expandable surgical chambers were tested. Both chambers had been modified to fit the microgravity work station without extending over the sides of the table. Both chambers were attached to a portable laminar flow generator which served two purposes: to keep the chambers expanded during use; and to provide an operative area environment free of contamination. During the tests, the chambers were placed on various parts of a total body moulage to simulate management of several types of trauma. The tests consisted of cleansing contusions, debridement of burns, and suturing of lacerations. Also, indigo carmine dye was deliberately injected into the chamber during the tests to determine the ease of cleansing the chamber walls after contamination by escaping fluids. Upon completion of the tests, the expandable surgical chambers were deflated, folded, and placed in a flattened state back into their original containers for storage and later disposal. Results are briefly discussed.

A New Electrospray Aerosol Generator with High Particle Transmission Efficiency

PubMed Central

Fu, Huijing; Patel, Anand C.; Holtzman, Michael J.; Chen, Da-Ren

2012-01-01

A new single-capillary electrospray (ES) aerosol generator has been developed for monodisperse particle production with maximal transmission efficiency. The new generator consists of both a spray chamber in a point-to-orifice-plate configuration and a charge reduction chamber that can hold up to 4 Nuclespot ionizers (Model P-2042, NRD Inc.). The 2 chambers are partitioned by an orifice plate. To optimize the particle transmission efficiency of the prototype, a systematic study was performed on the generator by varying the system setup and operation. Two key dimensions of the generator setup, the orifice diameter and the distance from the capillary tip to the orifice plate, were varied. Fluorescence analysis was applied to characterize the loss of ES-generated particles at different locations of the prototype. It was found that particle loss in the generator could be reduced by either increasing the orifice diameter or decreasing the distance between the capillary tip and the orifice plate. Increasing either the total radioactivity of the ionizers or the flowrate of the particle carrier gas also further decreased the particle loss in the system. The maximum particle transmission efficiency of 88.0% was obtained with the spray chamber fully opened to the charge reduction chamber, the capillary tip at the same level as the orifice plate, and 4 bipolar ionizers installed. PMID:22829715

The STREON Recirculation Chamber: An Advanced Tool to Quantify Stream Ecosystem Metabolism in the Benthic Zone

NASA Astrophysics Data System (ADS)

Brock, J. T.; Utz, R.; McLaughlin, B.

2013-12-01

The STReam Experimental Observatory Network is a large-scale experimental effort that will investigate the effects of eutrophication and loss of large consumers in stream ecosystems. STREON represents the first experimental effort undertaken and supported by the National Ecological Observatory Network (NEON).Two treatments will be applied at 10 NEON sites and maintained for 10 years in the STREON program: the addition of nitrate and phosphate to enrich concentrations by five times ambient levels and electrical fields that exclude top consumers (i.e., fish or invertebrates) of the food web from the surface of buried sediment baskets. Following a 3-5 week period, the sediment baskets will be extracted and incubated in closed, recirculating metabolic chambers to measure rates of respiration, photosynthesis, and nutrient uptake. All STREON-generated data will be open access and available on the NEON web portal. The recirculation chamber represents a critical infrastructural component of STREON. Although researchers have applied such chambers for metabolic and nutrient uptake measurements in the past, the scope of STREON demands a novel design that addresses multiple processes often neglected by earlier models. The STREON recirculation chamber must be capable of: 1) incorporating hyporheic exchange into the flow field to ensure measurements of respiration include the activity of subsurface biota, 2) operating consistently with heterogeneous sediments from sand to cobble, 3) minimizing heat exchange from the motor and external environment, 4) delivering a reproducible uniform flow field over the surface of the sediment basket, and 5) efficient assembly/disassembly with minimal use of tools. The chamber also required a means of accommodating an optical dissolved oxygen probe and a means to inject/extract water. A prototype STREON chamber has been designed and thoroughly tested. The flow field within the chamber has been mapped using particle imaging velocimetry (PIV) under various velocity settings. The extent of exchange with the sediment was assessed by means of a saline tracer injection and adjustment using flow-regulating components was explored. Performance under a broad range of temperatures (1 to 30 °C) was assessed. Finally, a novel heat-exchange mechanism meant to minimize warming during operations was evaluated. All prototype assessments demonstrate the applicability of the STREON chamber under a broad range of conditions. Though the STREON recirculation chamber has been designed to satisfy the specific needs of the STREON program, the open-access nature of the NEON network should facilitate scope expansion in the coming decades. The STREON recirculation chamber design and all prototype testing data will be accessible to facilitate chamber use elsewhere. The large number of chamber assemblies required for STREON operations should facilitate the acquisition of units by researchers working outside of the NEON network. Furthermore, the current scope of STREON includes the use of the chambers only once annually, thus a valuable tool for stream ecosystem measurements will be readily available at STREON sites for potential use by researchers interested in such measurements.

Ultra-low mass drift chambers

NASA Astrophysics Data System (ADS)

Assiro, R.; Cappelli, L.; Cascella, M.; De Lorenzis, L.; Grancagnolo, F.; Ignatov, F.; L'Erario, A.; Maffezzoli, A.; Miccoli, A.; Onorato, G.; Perillo, M.; Piacentino, G.; Rella, S.; Rossetti, F.; Spedicato, M.; Tassielli, G.; Zavarise, G.

2013-08-01

We present a novel low mass drift chamber concept, developed in order to fulfill the stringent requirements imposed by the experiments for extremely rare processes, which require high resolutions (order of 100-200 keV/c) for particle momenta in a range (50-100 MeV/c) totally dominated by the multiple scattering contribution. We describe a geometry optimization procedure and a new wiring strategy with a feed-through-less wire anchoring system developed and tested on a drift chamber prototype under completion at INFN-Lecce .

Beam tracking with micromegas & wire chambers in secondary electron detection configuration

NASA Astrophysics Data System (ADS)

Voštinar, M.; Fernández, B.; Pancin, J.; Alvarez, M. A. G.; Chaminade, T.; Damoy, S.; Doré, D.; Drouart, A.; Druillole, F.; Frémont, G.; Kebbiri, M.; Materna, T.; Monmarthe, E.; Panebianco, S.; Papaevangelou, T.; Riallot, M.; Savajols, H.; Spitaels, C.

2013-12-01

The focal plane of S3 (Super Separator Spectrometer), a new experimental area of SPIRAL2 at GANIL, will be used for identification of nuclei, and requires the reconstruction of their trajectories and velocities by the Time Of Flight (TOF) method. Classical tracking detectors used in-beam would generate a lot of angular and energy straggling due to their thickness. One solution is the use of a SED (Secondary Electron Detection), which consists of a thin emissive foil in beam coupled to a low pressure gaseous detector out of the beam, for the detection of secondary electrons ejected from the foil. Moreover, this type of detector can be used for classical beam tracking at low energies, or for example at NFS (GANIL) for the FALSTAFF experiment for the reconstruction of fission fragments trajectories. Several low pressure gaseous detectors such as wire chambers and Micromegas have been constructed and tested since 2008. High counting rate capabilities and good time resolution obtained in previous tests motivated the construction of a new real-size 2D prototype wire chamber and a 2D bulk Micromegas at low pressure. For the first time, spatial resolution of the Micromegas at low pressure (below 20 mbar) in the SED configuration was measured. Different tests have been performed in order to characterize time and spatial properties of both prototypes, giving spatial resolution in the horizontal (X) direction of 0.90(0.02) mm FWHM for the real size prototype and 0.72(0.08) mm FWHM for Micromegas, and a time resolution of ~ 110(25) ps for the real size prototype.

Isothermal Dendritic Growth Experiment - Science, engineering, and hardware development for USMP space flights

NASA Technical Reports Server (NTRS)

Glicksman, M. E.; Hahn, R. C.; Koss, M. B.; Tirmizi, S. H.; Selleck, M. E.; Velosa, A.; Winsa, E.

1991-01-01

The Isothermal Dendritic Growth Experiment (IDGE) has been designed to provide microgravity data on dendritic growth for a critical test of theory. This paper updates progress on constructing a crystal growth chamber suitable for space flight. The IDGE chamber is constructed from glass and stainless steel and is hermetically sealed by electron beam welds and glass-metal seals. Initial tests of the chambers sample's melting point plateau show that the new chamber design is capable of preserving the 99.9995 percent purity of succinonitrile. Dendrite growth can be initiated in the center of the IDGE chamber by means of thermo-electric coolers and a capillary injector tube (stinger). The new IDGE chamber is ready for fully integrated tests with the prototype IDGE engineering hardware at NASA's Lewis Research Center.

A Smart Cage With Uniform Wireless Power Distribution in 3D for Enabling Long-Term Experiments With Freely Moving Animals.

PubMed

Mirbozorgi, S Abdollah; Bahrami, Hadi; Sawan, Mohamad; Gosselin, Benoit

2016-04-01

This paper presents a novel experimental chamber with uniform wireless power distribution in 3D for enabling long-term biomedical experiments with small freely moving animal subjects. The implemented power transmission chamber prototype is based on arrays of parallel resonators and multicoil inductive links, to form a novel and highly efficient wireless power transmission system. The power transmitter unit includes several identical resonators enclosed in a scalable array of overlapping square coils which are connected in parallel to provide uniform power distribution along x and y. Moreover, the proposed chamber uses two arrays of primary resonators, facing each other, and connected in parallel to achieve uniform power distribution along the z axis. Each surface includes 9 overlapped coils connected in parallel and implemented into two layers of FR4 printed circuit board. The chamber features a natural power localization mechanism, which simplifies its implementation and ease its operation by avoiding the need for active detection and control mechanisms. A single power surface based on the proposed approach can provide a power transfer efficiency (PTE) of 69% and a power delivered to the load (PDL) of 120 mW, for a separation distance of 4 cm, whereas the complete chamber prototype provides a uniform PTE of 59% and a PDL of 100 mW in 3D, everywhere inside the chamber with a size of 27×27×16 cm(3).

High resolution muon tracking with resistive plate chambers

NASA Astrophysics Data System (ADS)

Baesso, P.; Cussans, D.; Davies, J.; Glaysher, P.; Thomay, C.; Vassallo, C.; Velthuis, J.; Quillin, S.; Robertson, S.; Steer, C.

2012-11-01

Following their introduction in the physics community in the early '80s the use of Resistive Plate Chambers (RPCs) as charged particles detectors has constantly increased. Low cost per unit area, good time resolution and easy of operation are some of the features that contributed to such large adoption and that make RPCs interesting for several applications not necessarily related to physics. We built a prototype detector to track cosmic muons and exploit the information provided by estimating the multiple coulomb scattering angle to determine the type of materials they traversed. Simulations show that the technique could be used to inspect a cargo container in a time of the order of minutes. The detector we built consists of six planes, each one providing X-Y readout over a 50 cm × 50 cm area. The readout scheme we adopted, based on multiplexing chips used in high energy physics, allowed us to use a limited amount of electronic output channels while still obtaining a spatial resolution lower than 1 mm. An overview of the detector and of the analysis performed on the data is provided.

Status and operation of the Linac4 ion source prototypes

NASA Astrophysics Data System (ADS)

Lettry, J.; Aguglia, D.; Andersson, P.; Bertolo, S.; Butterworth, A.; Coutron, Y.; Dallocchio, A.; Chaudet, E.; Gil-Flores, J.; Guida, R.; Hansen, J.; Hatayama, A.; Koszar, I.; Mahner, E.; Mastrostefano, C.; Mathot, S.; Mattei, S.; Midttun, Ø.; Moyret, P.; Nisbet, D.; Nishida, K.; O'Neil, M.; Ohta, M.; Paoluzzi, M.; Pasquino, C.; Pereira, H.; Rochez, J.; Sanchez Alvarez, J.; Sanchez Arias, J.; Scrivens, R.; Shibata, T.; Steyaert, D.; Thaus, N.; Yamamoto, T.

2014-02-01

CERN's Linac4 45 kV H- ion sources prototypes are installed at a dedicated ion source test stand and in the Linac4 tunnel. The operation of the pulsed hydrogen injection, RF sustained plasma, and pulsed high voltages are described. The first experimental results of two prototypes relying on 2 MHz RF-plasma heating are presented. The plasma is ignited via capacitive coupling, and sustained by inductive coupling. The light emitted from the plasma is collected by viewports pointing to the plasma chamber wall in the middle of the RF solenoid and to the plasma chamber axis. Preliminary measurements of optical emission spectroscopy and photometry of the plasma have been performed. The design of a cesiated ion source is presented. The volume source has produced a 45 keV H- beam of 16-22 mA which has successfully been used for the commissioning of the Low Energy Beam Transport (LEBT), Radio Frequency Quadrupole (RFQ) accelerator, and chopper of Linac4.

Advanced Materials and Manufacturing for Low-Cost, High-Performance Liquid Rocket Combustion Chambers

NASA Technical Reports Server (NTRS)

Williams, Brian E.; Arrieta, Victor M.

2013-01-01

A document describes the low-cost manufacturing of C103 niobium alloy combustion chambers, and the use of a high-temperature, oxidation-resistant coating that is superior to the standard silicide coating. The manufacturing process involved low-temperature spray deposition of C103 on removable plastic mandrels produced by rapid prototyping. Thin, vapor-deposited platinum-indium coatings were shown to substantially improve oxidation resistance relative to the standard silicide coating. Development of different low-cost plastic thrust chamber mandrel materials and prototyping processes (selective laser sintering and stereolithography) yielded mandrels with good dimensional accuracy (within a couple of mils) for this stage of development. The feasibility of using the kinetic metallization cold-spray process for fabrication of free-standing C1O3 thrusters on removable plastic mandrels was also demonstrated. The ambient and elevated temperature mechanical properties of the material were shown to be reasonably good relative to conventionally processed C103, but the greatest potential benefit is that coldsprayed chambers require minimal post-process machining, resulting in substantially lower machining and material costs. The platinum-iridium coating was shown to provide greatly increased oxidation resistance over the silicide when evaluated through oxyacetylene torch testing to as high as 300 F (= 150 C). The iridium component minimizes reaction with the niobium alloy chamber at high temperatures, and provides the high-temperature oxidation resistance needed at the throat.

Isothermal dendritic growth experiment: Science, engineering, and hardware development for USMP space flights

NASA Astrophysics Data System (ADS)

Glicksman, M. E.; Hahn, R. C.; Koss, M. B.; Tirmizi, S. H.; Selleck, M. E.; Velosa, A.; Winsa, E.

The Isothermal Dendritic Growth Experiment (IDGE) has been designed to provide microgravity data on dendritic growth for a critical test of theory. This paper updates our progress on constructing a crystal growth chamber suitable for space flight. The IDGE chamber is constructed from glass and stainless steel and is hermetically sealed by electron beam welds and glass-metal seals. Initial tests of the chambers sample's melting point plateau show that the new chamber design is capable of preserving the 99.9995 pct purity of succinonitrile (SCN). One can initiate dendrite growth in the center of the IDGE chamber by means of thermo-electric coolers and a capillary injector tube (stinger). The new IDGE chamber is ready for fully integrated tests with the prototype IDGE engineering hardware at NASA's Lewis Research Center.

Investigation of gaseous propellant combustion and associated injector/chamber design guidelines

NASA Technical Reports Server (NTRS)

Calhoon, D. F.; Ito, J. I.; Kors, D. L.

1973-01-01

Injector design criteria are provided for gaseous hydrogen-gaseous oxygen propellants. Design equations and procedures are presented which will allow an injector-chamber designer to a priori estimate of the performance, compatibility and stability characteristics of prototype injectors. The effects of chamber length, element geometry, thrust per element, mixture ratio, impingement angle, and element spacing were evaluated for four element concepts and their derivatives. The data from this series of tests were reduced to a single valued mixing function that describes the mixing potential of the various elements. Performance, heat transfer and stability data were generated for various mixture ratios, propellant temperatures, chamber pressures, contraction ratios, and chamber lengths. Applications of the models resulted in the design of procedures, whereby the performance and chamber heat flux can be calculated directly, and the injector stability estimated in conjunction with existing models.

Development of secondary chamber for tar cracking-improvement of wood pyrolysis performance in pre-vacuum chamber

NASA Astrophysics Data System (ADS)

Siahaan, S.; Homma, H.; Homma, H.

2018-02-01

Energy crisis and global warming, in other words, climate change are critical topics discussed in various parts of the world. Global warming primarily result from too much emission of carbon dioxide (CO2) in the atmosphere. To mitigate global warming, or climate change and improve electrification in rural areas, wood pyrolysis technology is developed in a laboratory scale, of which gases are directly applicable to the gas engine generator. Our laboratory has developed a prototype of wood pyrolysis plant with a pre-vacuum chamber. However, tar yield was around 40 wt% of feedstock. This research aims to reduce tar yield by secondary tar cracking. For the secondary tar cracking, a secondary pre-vacuum chamber is installed after primary pre-vacuum chamber. Gases generated in the primary pre-vacuum chamber are lead into the secondary chamber that is heated up to 1000 K. This paper reports performance of the secondary chamber for secondary tar cracking in homogeneous mode and heterogeneous mode with char.

The Other Shoe: An Early Operant Conditioning Chamber for Pigeons.

PubMed

Sakagami, Takayuki; Lattal, Kennon A

2016-05-01

We describe an early operant conditioning chamber fabricated by Harvard University instrument maker Ralph Gerbrands and shipped to Japan in 1952 in response to a request of Professor B. F. Skinner by Japanese psychologists. It is a rare example, perhaps the earliest still physically existing, of such a chamber for use with pigeons. Although the overall structure and many of the components are similar to contemporary pigeon chambers, several differences are noted and contrasted to evolutionary changes in this most important laboratory tool in the experimental analysis of behavior. The chamber also is testimony to the early internationalization of behavior analysis.

Cathode readout with stripped resistive drift tubes

NASA Astrophysics Data System (ADS)

Bychkov, V. N.; Kekelidze, G. D.; Novikov, E. A.; Peshekhonov, V. D.; Shafranov, M. D.; Zhiltsov, V. E.

1995-12-01

A straw tube drift chamber prototype has been constructed and tested. The straw tube material is mylar film covered with a carbon layer with a resistivity of 0.5, 30 and 70 kΩ/□. Both the anode wire and the cathode strip signals were detected to study the behaviour of the chamber in the presence of X-ray ionization. The construction and the results of the study are presented.

Micro Ion Mobility Sensor for In Situ Monitoring of Contaminated Groundwater

DTIC Science & Technology

2012-01-01

volts per ampere V/cm volts per centimeter VC voltage compensation Vd drift velocity VOC volatile organic compounds Technical...experience in field test. 1.3 RESULTS Lab testing showed that a prototype sensor is capable of uniquely identifying 32 volatile organic compounds (VOC...3) water-loop, (4) water-to-vapor chamber, (5) permanent collector , (6) second-stage carrier gas inlet, (7) vapor-to-vapor chamber, (8) permanent

An architecture for rapid prototyping of control schemes for artificial ventricles.

PubMed

Ficola, Antonio; Pagnottelli, Stefano; Valigi, Paolo; Zoppitelli, Maurizio

2004-01-01

This paper presents an experimental system aimed at rapid prototyping of feedback control schemes for ventricular assist devices, and artificial ventricles in general. The system comprises a classical mock circulatory system, an actuated bellow-based ventricle chamber, and a software architecture for control schemes implementation and experimental data acquisition, visualization and storing. Several experiments have been carried out, showing good performance of ventricular pressure tracking control schemes.

Final Report for DUSEL R&D: BetaCage: A Screener of Ultra-Low-Level Radioactive Surface Contamination

DOE Office of Scientific and Technical Information (OSTI.GOV)

Golwala, Sunil R.

2013-12-20

The eventual full-size, radiopure BetaCage will be a low-background, atmospheric-pressure neon drift chamber with unprecedented sensitivity to emitters of low-energy electrons and alpha particles. We expect that the prototype BetaCage already developed will be an excellent screener of alpha particles. Both the prototype and final BetaCage will provide new infrastructure for rare-event science.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lill, R.; Sereno, N.; Yang, B.

The Advanced Photon Source (APS) is currently in the preliminary design phase for the multi-bend achromat (MBA) lattice upgrade. Beam stability is critical for the MBA and will require long term drift defined as beam mo-tion over a seven-day timescale to be no more than 1 mi-cron at the insertion device locations and beam angle change no more than 0.25 micro-radian. Mechanical stabil-ity of beam position monitor (BPM) pickup electrodes mounted on insertion device vacuum chambers place a fun-damental limitation on long-term beam stability for inser-tion device beamlines. We present the design and imple-mentation of prototype mechanical motion system (MMS)more » instrumentation for quantifying this type of motion specif-ically in the APS accelerator tunnel and experiment hall floor under normal operating conditions. The MMS pres-ently provides critical position information on the vacuum chamber and BPM support systems. Initial results of the R&D prototype systems have demonstrated that the cham-ber movements far exceed the long-term drift tolerance specified for the APS Upgrade MBA storage ring.« less

Short-time-scale left ventricular systolic dynamics. Evidence for a common mechanism in both left ventricular chamber and heart muscle mechanics.

PubMed

Campbell, K B; Shroff, S G; Kirkpatrick, R D

1991-06-01

Based on the premise that short-time-scale, small-amplitude pressure/volume/outflow behavior of the left ventricular chamber was dominated by dynamic processes originating in cardiac myofilaments, a prototype model was built to predict pressure responses to volume perturbations. In the model, chamber pressure was taken to be the product of the number of generators in a pressure-bearing state and their average volumetric distortion, as in the muscle theory of A.F. Huxley, in which force was equal to the number of attached crossbridges and their average lineal distortion. Further, as in the muscle theory, pressure generators were assumed to cycle between two states, the pressure-bearing state and the non-pressure-bearing state. Experiments were performed in the isolated ferret heart, where variable volume decrements (0.01-0.12 ml) were removed at two commanded flow rates (flow clamps, -7 and -14 ml/sec). Pressure responses to volume removals were analyzed. Although the prototype model accounted for most features of the pressure responses, subtle but systematic discrepancies were observed. The presence or absence of flow and the magnitude of flow affected estimates of model parameters. However, estimates of parameters did not differ when the model was fitted to flow clamps with similar magnitudes of flows but different volume changes. Thus, prototype model inadequacies were attributed to misrepresentations of flow-related effects but not of volume-related effects. Based on these discrepancies, an improved model was built that added to the simple two-state cycling scheme, a pathway to a third state. This path was followed only in response to volume change. The improved model eliminated the deficiencies of the prototype model and was adequate in accounting for all observations. Since the template for the improved model was taken from the cycling crossbridge theory of muscle contraction, it was concluded that, in spite of the complexities of geometry, architecture, and regional heterogeneity of function and structure, crossbridge mechanisms dominated the short-time-scale dynamics of left ventricular chamber behavior.

Regeneratively cooled rocket engine for space storable propellants

NASA Technical Reports Server (NTRS)

Wagner, W. R.

1973-01-01

Analysis, design, fabrication, and test efforts were performed for the existing OF2/B2H6 regeneratively cooled lK (4448 N) thrust chamber to illustrate simultaneous B2H6 fuel and OF2 oxidizer cooling and to provide results for a gaseous propellant condition injected into the combustion chamber. Data derived from performance, thermal and flow measurements confirmed predictions derived from previous test work and from concurrent analytical study. Development data derived from the experimental study were indicated to be sufficient to develop a preflight thrust chamber demonstrator prototype for future space mission objectives.

A Transonic and Surpersonic Investigation of Jet Exhaust Plume Effects on the Afterbody and Base Pressures of a Body of Revolution

NASA Technical Reports Server (NTRS)

Andrews, C. D.; Cooper, C. E., Jr.

1974-01-01

An experimental aerodynamic investigation was conducted to provide data for studies to determine the criteria for simulating rocket engine plume induced aerodynamic effects in the wind tunnel using a simulated gaseous plume. Model surface and base pressure data were obtained in the presence of both a simulated and a prototype gaseous plume for a matrix of plume properties to enable investigators to determine the parameters that correlate the simulated and prototype plume-induced data. The test program was conducted in the Marshall Space Flight Center's 14 x 14-inch trisonic wind tunnel using two models, the first being a strut mounted cone-ogive-cylinder model with a fineness ratio of 9. Model exterior pressures, model plenum chamber and nozzle performance data were obtained at Mach numbers of 0.9, 1.2, 1.46, and 3.48. The exhaust plume was generated by using air as the simulant gas, or Freon-14 (CF4) as the prototype gas, over a chamber pressure range from 0 to 2,000 psia and a total temperature range from 50 to 600 F.

Design and performance of a custom ASIC digitizer for wire chamber readout in 65 nm CMOS technology

NASA Astrophysics Data System (ADS)

Lee, M. J.; Brown, D. N.; Chang, J. K.; Ding, D.; Gnani, D.; Grace, C. R.; Jones, J. A.; Kolomensky, Y. G.; von der Lippe, H.; Mcvittie, P. J.; Stettler, M. W.; Walder, J.-P.

2015-06-01

We present the design and performance of a prototype ASIC digitizer for integrated wire chamber readout, implemented in 65 nm commercial CMOS technology. Each channel of the 4-channel prototype is composed of two 16-bit Time-to-Digital Converters (TDCs), one 8-bit Analog-to-Digital Converter (ADC), a front-end preamplifier and shaper, plus digital and analog buffers that support a variety of digitization chains. The prototype has a multiplexed digital backend that executes a state machine, distributes control and timing signals, and buffers data for serial output. Laboratory bench tests measure the absolute TDC resolution between 74 ps and 480 ps, growing with the absolute delay, and a relative time resolution of 19 ps. Resolution outliers due to cross-talk between clock signals and supply or reference voltages are seen. After calibration, the ADC displays good linearity and noise performance, with an effective number of bits of 6.9. Under normal operating conditions the circuit consumes 32 mW per channel. Potential design improvements to address the resolution drift and tails are discussed.

Cathode readout with stripped resistive drift tubes

NASA Astrophysics Data System (ADS)

Bychkov, V. N.; Kekelidze, G. D.; Novikov, E. A.; Peshekhonov, V. D.; Shafranov, M. D.; Zhiltsov, V. E.

1994-11-01

A straw tube drift chamber prototype has been constructed and tested. The straw tube material is mylar film covered with carbon layer of resistivity 0.5, 30 and 70 k Ohm/sq. The gas mixture used was Ar/CH4. Both the anode wire and cathode signals were detected in order to study the behaviour of the chamber in the presence of X-ray ionization. The construction and the results of the study are presented.

A new pressure chamber to study the biosynthetic response of articular cartilage to mechanical loading.

PubMed

Steinmeyer, J; Torzilli, P A; Burton-Wurster, N; Lust, G

1993-01-01

A prototype chamber was used to apply a precise cyclic or static load on articular cartilage explants under sterile conditions. A variable pressure, pneumatic controller was constructed to power the chamber's air cylinder, capable of applying, with a porous load platen, loads of up to 10 MPa at cycles ranging from 0 to 10 Hz. Pig articular cartilage explants were maintained successfully in this chamber for 2 days under cyclic mechanical loading of 0.5 Hz, 0.5 MPa. Explants remained sterile, viable and metabolically active. Cartilage responded to this load with a decreased synthesis of fibronectin and a small but statistically significant elevation in proteoglycan content. Similar but less extensive effects on fibronectin synthesis were observed with the small static load (0.016 MPa) inherent in the design of the chamber.

SAMPA Chip: the New 32 Channels ASIC for the ALICE TPC and MCH Upgrades

NASA Astrophysics Data System (ADS)

Adolfsson, J.; Ayala Pabon, A.; Bregant, M.; Britton, C.; Brulin, G.; Carvalho, D.; Chambert, V.; Chinellato, D.; Espagnon, B.; Hernandez Herrera, H. D.; Ljubicic, T.; Mahmood, S. M.; Mjörnmark, U.; Moraes, D.; Munhoz, M. G.; Noël, G.; Oskarsson, A.; Osterman, L.; Pilyar, A.; Read, K.; Ruette, A.; Russo, P.; Sanches, B. C. S.; Severo, L.; Silvermyr, D.; Suire, C.; Tambave, G. J.; Tun-Lanoë, K. M. M.; van Noije, W.; Velure, A.; Vereschagin, S.; Wanlin, E.; Weber, T. O.; Zaporozhets, S.

2017-04-01

This paper presents the test results of the second prototype of SAMPA, the ASIC designed for the upgrade of read-out front end electronics of the ALICE Time Projection Chamber (TPC) and Muon Chamber (MCH). SAMPA is made in a 130 nm CMOS technology with 1.25 V nominal voltage supply and provides 32 channels, with selectable input polarity, and three possible combinations of shaping time and sensitivity. Each channel consists of a Charge Sensitive Amplifier, a semi-Gaussian shaper and a 10-bit ADC; a Digital Signal Processor provides digital filtering and compression capability. In the second prototype run both full chip and single test blocks were fabricated, allowing block characterization and full system behaviour studies. Experimental results are here presented showing agreement with requirements for both the blocks and the full chip.

A novel enhanced diffusion sampler for collecting gaseous pollutants without air agitation.

PubMed

Pan, Xuelian; Zhuo, Shaojie; Zhong, Qirui; Chen, Yuanchen; Du, Wei; Cheng, Hefa; Wang, Xilong; Zeng, Eddy Y; Xing, Baoshan; Tao, Shu

2018-03-06

A novel enhanced diffusion sampler for collecting gaseous phase polycyclic aromatic hydrocarbons (PAHs) without air agitation is proposed. The diffusion of target compounds into a sampling chamber is facilitated by continuously purging through a closed-loop flow to create a large concentration difference between the ambient air and the air in the sampling chamber. A glass-fiber filter-based prototype was developed. It was demonstrated that the device could collect gaseous PAHs at a much higher rate (1.6 ± 1.4 L/min) than regular passive samplers, while the ambient air is not agitated. The prototype was also tested in both the laboratory and field for characterizing the concentration gradients over a short distance from the soil surface. The sampler has potential to be applied in other similar situations to characterize the concentration profiles of other chemicals.

Search for α-Cluster Structure in Exotic Nuclei with the Prototype Active-Target Time-Projection Chamber

NASA Astrophysics Data System (ADS)

Fritsch, A.; Ayyad, Y.; Bazin, D.; Beceiro-Novo, S.; Bradt, J.; Carpenter, L.; Cortesi, M.; Mittig, W.; Suzuki, D.; Ahn, T.; Kolata, J. J.; Becchetti, F. D.; Howard, A. M.

2016-03-01

Some exotic nuclei appear to exhibit α-cluster structure. While various theoretical models currently describe such clustering, more experimental data are needed to constrain model predictions. The Prototype Active-Target Time-Projection Chamber (PAT-TPC) has low-energy thresholds for charged-particle decay and a high luminosity due to its thick gaseous active target volume, making it well-suited to search for low-energy α-cluster reactions. Radioactive-ion beams produced by the TwinSol facility at the University of Notre Dame were delivered to the PAT-TPC to study nuclei including 14C and 14O via α-resonant scattering. Differential cross sections and excitation functions were measured. Preliminary results from our recent experiments will be presented. This work is supported by the U.S. National Science Foundation.

Warm/cold cloud processes

NASA Technical Reports Server (NTRS)

Davis, M. H.

1981-01-01

Final development of a gravimetric test for performance evaluation of a precision saturator is described. The design and development of a prototype droplet levitation chamber is discussed. Technical assistance to the MSFC Airborne Laser Doppler Program is reported.

Plasma chamber testing of advanced photovoltaic solar array coupons

NASA Technical Reports Server (NTRS)

Hillard, G. Barry

1994-01-01

The solar array module plasma interactions experiment is a space shuttle experiment designed to investigate and quantify the high voltage plasma interactions. One of the objectives of the experiment is to test the performance of the Advanced Photovoltaic Solar Array (APSA). The material properties of array blanket are also studied as electric insulators for APSA arrays in high voltage conditions. Three twelve cell prototype coupons of silicon cells were constructed and tested in a space simulation chamber.

Wire Chambers and Cherenkov Detectors at Fermilab Test Beam Facility

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tame Narvaez, Karla

2017-01-01

Fermilab Test Beam Facility (FTBF) is dedicated to helping scientists test their prototypes. For this, FTBF has instrumentation that is very useful for the users. However, before a user can test a detector, it is necessary to ensure the facility has the characteristics they need. During this summer, we studied beam properties by collecting Cherenkov and wire chamber data. Analyzed data will be used for updating the general information that FTBF posts on a web page.

Integration of the ATLAS FE-I4 Pixel Chip in the Mini Time Projection Chamber

NASA Astrophysics Data System (ADS)

Lopez-Thibodeaux, Mayra; Garcia-Sciveres, Maurice; Kadyk, John; Oliver-Mallory, Kelsey

2013-04-01

This project deals with development of readout for a Time Projection Chamber (TPC) prototype. This is a type of detector proposed for direct detection of dark matter (WIMPS) with direction information. The TPC is a gaseous charged particle tracking detector composed of a field cage and a gas avalanche detector. The latter is made of two Gas Electron Multipliers in series, illuminating a pixel readout integrated circuit, which measures the distribution in position and time of the output charge. We are testing the TPC prototype, filled with ArCO2 gas, using a Fe-55 x-ray source and cosmic rays. The present prototype uses an FE-I3 chip for readout. This chip was developed about 10 years ago and is presently in use within the ATLAS pixel detector at the LHC. The aim of this work is to upgrade the TPC prototype to use an FE-I4 chip. The FE-I4 has an active area of 336 mm^2 and 26880 pixels, over nine times the number of pixels in the FE-I3 chip, and an active area about six times as much. The FE-I4 chip represents the state of the art of pixel detector readout, and is presently being used to build an upgrade of the ATLAS pixel detector.

Young inflorescence-bearing shoots with roots of Tradescantia clone BNL 4430 cultivated in nutrient solution circulating systems: an alternative to potted plants and cuttings for mutagenicity tests.

PubMed

Shima, N; Xiao, L Z; Sakuramoto, F; Ichikawa, S

1997-12-12

The use of young inflorescence-bearing shoots with roots of Tradescantia clone BNL 4430 cultivated in a nutrient solution circulating (NSC) growth chamber was tested and developed as an alternative method for using Tradescantia plants in mutagenicity testings. The NSC growth chamber was designed for our requirements, based on trial cultivations of the shoots with roots in its smaller-sized prototype. The nutrient solution used was a 1/2500 Hyponex solution. The characteristics of this clone, i.e., many new shoots constantly emerging from the basal nodes one after another and its short height favorable for early flowering, made it possible to prepare many young inflorescence-bearing shoots with roots at one time. A simplified NSC cultivation system could also be developed at a lower cost, and by using it together with the NSC growth chamber, recycling of untreated materials was established for supplying steadily enough amounts of young inflorescence-bearing shoots with roots for mutagenicity testings. Compared with traditional methods of using potted plants or cuttings, the new method exhibited more stable flower production, better stamen-hair growth and a significantly lower spontaneous (background) mutation frequency, and could produce more inflorescences per space. The use of such young inflorescence-bearing shoots with roots was therefore judged to be satisfactory to serve as a new mutagenicity test system alternating with potted plants and cuttings.

Characterization of HIRF Susceptibility Threshold for a Prototype Implementation of an Onboard Data Network

NASA Technical Reports Server (NTRS)

Torres-Pomales, Wilfredo

2012-01-01

An experiment was conducted to characterize the effects of HIRF-induced upsets on a prototype onboard data network. The experiment was conducted at the NASA Langley Research Center s High Intensity Radiation Field Laboratory and used a generic distributed system prototyping platform to realize the data network. This report presents the results of the hardware susceptibility threshold characterization which examined the dependence of measured susceptibility on factors like the frequency and modulation of the radiation, layout of the physical nodes and position of the nodes in the test chamber. The report also includes lessons learned during the development and execution of the experiment.

Surface plasma source with saddle antenna radio frequency plasma generator.

PubMed

Dudnikov, V; Johnson, R P; Murray, S; Pennisi, T; Piller, C; Santana, M; Stockli, M; Welton, R

2012-02-01

A prototype RF H(-) surface plasma source (SPS) with saddle (SA) RF antenna is developed which will provide better power efficiency for high pulsed and average current, higher brightness with longer lifetime and higher reliability. Several versions of new plasma generators with small AlN discharge chambers and different antennas and magnetic field configurations were tested in the plasma source test stand. A prototype SA SPS was installed in the Spallation Neutron Source (SNS) ion source test stand with a larger, normal-sized SNS AlN chamber that achieved unanalyzed peak currents of up to 67 mA with an apparent efficiency up to 1.6 mA∕kW. Control experiments with H(-) beam produced by SNS SPS with internal and external antennas were conducted. A new version of the RF triggering plasma gun has been designed. A saddle antenna SPS with water cooling is fabricated for high duty factor testing.

MWPC prototyping and testing for STAR inner TPC upgrade

NASA Astrophysics Data System (ADS)

Shen, F.; Wang, S.; Yang, C.; Xu, Q.

2017-06-01

STAR experiment at the Relativistic Heavy Ion Collider (RHIC) is upgrading the inner sectors of the Time Projection Chamber (iTPC). The iTPC upgrade project will increase the segmentation on the inner pad plane from 13 to 40 pad rows and renew the inner sector wire chambers. The upgrade will expand the TPC's acceptance from |η|<=1.0 to |η|<=1.5. Furthermore, the detector will have better acceptance for tracks with low momentum, as well as better resolution in both momentum and dE/dx for tracks of all momenta. The enhanced measurement capabilities of STAR-iTPC upgrade are crucial to the physics program of the Phase II of Beam Energy Scan (BES-II) at RHIC during 2019-2020, in particular the QCD phase transition study. In this proceedings, I will discuss the iTPC MWPC module fabrication and testing results from the first full size iTPC MWPC pre-prototype made at Shandong University.

Photon Detector System Timing Performance in the DUNE 35-ton Prototype Liquid Argon Time Projection Chamber

DOE Office of Scientific and Technical Information (OSTI.GOV)

Adams, D.L.; et al.

The 35-ton prototype for the Deep Underground Neutrino Experiment far detector was a single-phase liquid argon time projection chamber with an integrated photon detector system, all situated inside a membrane cryostat. The detector took cosmic-ray data for six weeks during the period of February 1, 2016 to March 12, 2016. The performance of the photon detection system was checked with these data. An installed photon detector was demonstrated to measure the arrival times of cosmic-ray muons with a resolution better than 32 ns, limited by the timing of the trigger system. A measurement of the timing resolution using closely-spaced calibration pulses yielded a resolution of 15 ns for pulses at a level of 6 photo-electrons. Scintillation light from cosmic-ray muons was observed to be attenuated with increasing distance with a characteristic length ofmore » $$155 \\pm 28$$ cm.« less

Search for α -Cluster Structure in Exotic Nuclei with the Prototype Active-Target Time-Projection Chamber

NASA Astrophysics Data System (ADS)

Fritsch, A.; Ayyad, Y.; Bazin, D.; Beceiro-Novo, S.; Bradt, J.; Carpenter, L.; Cortesi, M.; Mittig, W.; Suzuki, D.; Ahn, T.; Kolata, J. J.; Howard, A. M.; Becchetti, F. D.; Wolff, M.

Some exotic nuclei appear to exhibit α -cluster structure, which may impact nucleosynthesis reaction rates. While various theoretical models currently describe such clustering, more experimental data are needed to constrain model predictions. The Prototype Active-Target Time-Projection Chamber (PAT-TPC) has low-energy thresholds for charged-particle decay and a high detection efficiency due to its thick gaseous active target volume, making it well-suited to search for low-energy α -cluster reactions. Radioactive-ion beams produced by the TwinSol facility at the University of Notre Dame were delivered to the PAT-TPC to study 14C via α -resonant scattering. Differential cross sections and excitation functions were measured and show evidence of three-body exit channels. Additional data were measured with an updated Micromegas detector more sensitive to three-body decay. Preliminary results are presented.

A GEM-TPC in twin configuration for the Super-FRS tracking of heavy ions at FAIR

NASA Astrophysics Data System (ADS)

García, F.; Grahn, T.; Hoffmann, J.; Jokinen, A.; Kaya, C.; Kunkel, J.; Rinta-Antila, S.; Risch, H.; Rusanov, I.; Schmidt, C. J.; Simon, H.; Simons, C.; Turpeinen, R.; Voss, B.; Äystö, J.; Winkler, M.

2018-03-01

The GEM-TPC described herein will be part of the standard beam-diagnostics equipment of the Super-FRS. This chamber will provide tracking information for particle identification at rates up to 1 MHz on an event-by-event basis. The key requirements of operation for these chambers are: close to 100% tracking efficiency under conditions of high counting rate, spatial resolution below 1 mm and a superb large dynamic range covering projectiles from Z = 1 up to Z = 92. The current prototype consists of two GEM-TPCs inside a single vessel, which are operating independently and have electrical drift fields in opposite directions. The twin configuration is done by flipping one of the GEM-TPCs on the middle plane with respect to the second one. In order to put this development in context, the evolution of previous prototypes will be described and its performances discussed. Finally, this chamber was tested at the University of Jyväskylä accelerator with proton projectiles and at GSI with Uranium, Xenon, fragments and Carbon beams. The results obtained have shown a position resolution between 120 to 300 μm at moderate counting rate under conditions of full tracking efficiency.

Angular resolution of stacked resistive plate chambers

DOE Office of Scientific and Technical Information (OSTI.GOV)

Samuel, Deepak; Onikeri, Pratibha B.; Murgod, Lakshmi P., E-mail: deepaksamuel@cuk.ac.in, E-mail: pratibhaonikeri@gmail.com, E-mail: lakshmipmurgod@gmail.com

We present here detailed derivations of mathematical expressions for the accuracy in the arrival direction of particles estimated using a set of stacked resistive plate chambers (RPCs). The expressions are validated against experimental results using data collected from the prototype detectors (without magnet) of the upcoming India-based Neutrino Observatory (INO). We also present a theoretical estimate of angular resolution of such a setup. In principle, these expressions can be used for any other detector with an architecture similar to that of RPCs.

Rapid prototype fabrication processes for high-performance thrust cells

NASA Technical Reports Server (NTRS)

Hunt, K.; Chwiedor, T.; Diab, J.; Williams, R.

1994-01-01

The Thrust Cell Technologies Program (Air Force Phillips Laboratory Contract No. F04611-92-C-0050) is currently being performed by Rocketdyne to demonstrate advanced materials and fabrication technologies which can be utilized to produce low-cost, high-performance thrust cells for launch and space transportation rocket engines. Under Phase 2 of the Thrust Cell Technologies Program (TCTP), rapid prototyping and investment casting techniques are being employed to fabricate a 12,000-lbf thrust class combustion chamber for delivery and hot-fire testing at Phillips Lab. The integrated process of investment casting directly from rapid prototype patterns dramatically reduces design-to-delivery cycle time, and greatly enhances design flexibility over conventionally processed cast or machined parts.

High-frequency monopole sound source for anechoic chamber qualification

NASA Astrophysics Data System (ADS)

Saussus, Patrick; Cunefare, Kenneth A.

2003-04-01

Anechoic chamber qualification procedures require the use of an omnidirectional monopole sound source. Required characteristics for these monopole sources are explicitly listed in ISO 3745. Building a high-frequency monopole source that meets these characteristics has proved difficult due to the size limitations imposed by small wavelengths at high frequency. A prototype design developed for use in hemianechoic chambers employs telescoping tubes, which act as an inverse horn. This same design can be used in anechoic chambers, with minor adaptations. A series of gradually decreasing brass telescoping tubes is attached to the throat of a well-insulated high-frequency compression driver. Therefore, all of the sound emitted from the driver travels through the horn and exits through an opening of approximately 2.5 mm. Directivity test data show that this design meets all of the requirements set forth by ISO 3745.

A Nano-Thin Film-Based Prototype QCM Sensor Array for Monitoring Human Breath and Respiratory Patterns.

PubMed

Selyanchyn, Roman; Wakamatsu, Shunichi; Hayashi, Kenshi; Lee, Seung-Woo

2015-07-31

Quartz crystal microbalance (QCM) sensor array was developed for multi-purpose human respiration assessment. The sensor system was designed to provide feedback for human respiration. Thorough optimization of measurement conditions: air flow, temperature in the QCM chamber, frequency measurement rate, and electrode position regarding to the gas flow-was performed. As shown, acquisition of respiratory parameters (rate and respiratory pattern) could be achieved even with a single electrode used in the system. The prototype system contains eight available QCM channels that can be potentially used for selective responses to certain breath chemicals. At present, the prototype machine is ready for the assessment of respiratory functions in larger populations in order to gain statistical validation. To the best of our knowledge, the developed prototype is the only respiratory assessment system based on surface modified QCM sensors.

A drift chamber tracking system for muon scattering tomography applications

NASA Astrophysics Data System (ADS)

Burns, J.; Quillin, S.; Stapleton, M.; Steer, C.; Snow, S.

2015-10-01

Muon scattering tomography (MST) allows the identification of shielded high atomic number (high-Z) materials by measuring the scattering angle of cosmic ray muons passing through an inspection region. Cosmic ray muons scatter to a greater degree due to multiple Coulomb scattering in high-Z materials than low-Z materials, which can be measured as the angular difference between the incoming and outgoing trajectories of each muon. Measurements of trajectory are achieved by placing position sensitive particle tracking detectors above and below the inspection volume. By localising scattering information, the point at which a series of muons scatter can be used to reconstruct an image, differentiating high, medium and low density objects. MST is particularly useful for differentiating between materials of varying density in volumes that are difficult to inspect visually or by other means. This paper will outline the experimental work undertaken to develop a prototype MST system based on drift chamber technology. The planar drift chambers used in this prototype measure the longitudinal interaction position of an ionising particle from the time taken for elections, liberated in the argon (92.5%), carbon dioxide (5%), methane (2.5%) gas mixture, to reach a central anode wire. Such a system could be used to enhance the detection of shielded radiological material hidden within regular shipping cargo.

Experimental evaluation of a 600 lbf spacecraft rocket engine.

NASA Technical Reports Server (NTRS)

Hoehn, F. W.

1972-01-01

Experimental results are presented for a long-duration-capability (1000-sec), space-storable, bipropellant liquid rocket motor burning fluorine/hydrazine or FLOX/monomethylhydrazine. The interrelationship between injected mixture ratio and the per cent film cooling on vacuum specific impulse performance and chamber heat transfer is given. Experimental sea level measurements are used to predict space vacuum performance based upon simplified JANNAF reference procedures. Dynamic combustion stability is demonstrated over a wide range of operating conditions. Analytical results of char penetration, erosion, and ablative wall temperature distributions are presented for prototype chamber designs.

Hollow Fiber Spacesuit Water Membrane Evaporator Development and Testing for Advanced Spacesuits

NASA Technical Reports Server (NTRS)

Bue, Grant C.; Trevino, Luis A.; Tsioulos, Gus; Settles, Joseph; Colunga, Aaron; Vogel, Matthew; Vonau, Walt

2010-01-01

The spacesuit water membrane evaporator (SWME) is being developed to perform the thermal control function for advanced spacesuits to take advantage of recent advances in micropore membrane technology in providing a robust heat-rejection device that is potentially less sensitive to contamination than is the sublimator. Principles of a sheet membrane SWME design were demonstrated using a prototypic test article that was tested in a vacuum chamber at JSC in July 1999. The Membrana Celgard X50-215 microporous hollow fiber (HoFi) membrane was selected after recent contamination tests as the most suitable candidate among commercial alternatives for HoFi SWME prototype development. A design that grouped the fiber layers into stacks, which were separated by small spaces and packaged into a cylindrical shape, was developed into a full-scale prototype consisting 14,300 tube bundled into 30 stacks, each of which are formed into a chevron shape and separated by spacers and organized into three sectors of ten nested stacks. Vacuum chamber testing has been performed characterize heat rejection as a function of inlet water temperature and water vapor backpressure and to show contamination resistance to the constituents expected to be found in potable water produced by the distillation processes. Other tests showed the tolerance to freezing and suitability to reject heat in a Mars pressure environment.

Assembly techniques for ultra-low mass drift chambers

NASA Astrophysics Data System (ADS)

Assiro, R.; Cascella, M.; Grancagnolo, F.; L'Erario, A.; Miccoli, A.; Rella, S.; Spedicato, M.; Tassielli, G.

2014-03-01

We presents a novel technique for the fast assembly of next generation ultra low mass drift chambers offering space point resolution of the order of 100 μm and high tolerance to pile-up. The chamber design has been developed keeping in mind the requirements for the search of rare processes: high resolutions (order of 100-200 KeV/c) for particles momenta in a range (50-100 MeV/c) totally dominated by the multiple scattering contribution (e.g., muon and kaon decay experiment such as MEG at PSI and Mu2e and ORKA at Fermilab). We describe a novel wiring strategy enabling the semiautomatic wiring of a complete layer with a high degree of control over wire tension and position. We also present feed-through-less wire anchoring system. These techniques have been already implemented at INFN-Lecce in the construction of a prototype drift chamber to be soon tested with cosmic rays and particle beams.

A High Resolution Liquid Xenon Imaging Telescope for 0.3-10 MeV Gamma Ray Astrophysics: Construction and Initial Balloon Flights

NASA Technical Reports Server (NTRS)

Aprile, Elena

1993-01-01

The results achieved with a 3.5 liter liquid xenon time projection chamber (LXe-TPC) prototype during the first year include: the efficiency of detecting the primary scintillation light for event triggering has been measured to be higher than 85%; the charge response has been measured to be stable to within 0.1% for a period of time of about 30 hours; the electron lifetime has been measured to be in excess of 1.3 ms; the energy resolution has been measured to be consistent with previous results obtained with small volume chambers; X-Y gamma ray imaging has been demonstrated with a nondestructive orthogonal wires readout; Monte Carlo simulation results on detection efficiency, expected background count rate at balloon altitude, background reduction algorithms, telescope response to point-like and diffuse sources, and polarization sensitivity calculations; and work on a 10 liter LXe-TPC prototype and gas purification/recovery system.

Prototype Aerogel Insulation for Melamine-Foam Substitute: Critical Space Station Express Rack Technology

NASA Technical Reports Server (NTRS)

Noever, David A.; Sibille, Laurent; Smith, David; Cronise, Raymond

1998-01-01

There is a current lack of environmentally acceptable foams to insulate Long-Duration Human Spaceflight Missions, including the experimental Express Rack for the Space Station. A recent 60-day manned test in a sealed chamber at Johnson Space Center (JSC) was nearly aborted, because of persistently high formaldehyde concentrations in the chamber. Subsequent investigation showed that the source was melamine foam (used extensively for acoustic insulation). The thermal and acoustic potential for melamine-foam substitutes is evaluated for scale-up to a silica-based foam and aerogel, which is environmentally benign for long duration space flight. These features will be discussed in reference to an aerogel prototype to: 1) assemble material strength data for various formulated aerogels, both silica and organic carbon aerogels; 2) assemble the aerogel into panels of mylar/vacuum-encapsulated rigid boards which can be molded in various shapes and rigidities; and 3) describe a process for space applications for formaldehyde-free, long duration thermal and acoustic insulators.

Filtration of Carbon Particulate Emissions from a Plasma Pyrolysis Assembly

NASA Technical Reports Server (NTRS)

Agui, Juan H.; Green, Robert; Vijayakumar, R.; Berger, Gordon; Greenwood, Zach; Abney, Morgan; Peterson, Elspeth

2016-01-01

NASA is investigating plasma pyrolysis as a candidate technology that will enable the recovery of hydrogen from the methane produced by the ISS Sabatier Reactor. The Plasma Pyrolysis Assembly (PPA) is the current prototype of this technology which converts the methane product from the Carbon Dioxide Reduction Assembly (CRA) to acetylene and hydrogen with 90% or greater conversion efficiency. A small amount of solid carbon particulates are generated as a side product and must be filtered before the acetylene is removed and the hydrogen-rich gas stream is recycled back to the CRA. We discuss developmental work on several options for filtering out the carbon particulate emissions from the PPA exit gas stream. The filtration technologies and concepts investigated range from fibrous media to monolithic ceramic and sintered metal media. This paper describes the different developed filter prototypes and characterizes their performance from integrated testing at the Environmental Chamber (E-Chamber) at MSFC. In addition, characterization data on the generated carbon particulates, that help to define filter requirements, are also presented.

First Results from the DUNE 35-ton Prototype using Cosmics

NASA Astrophysics Data System (ADS)

Insler, Jonathan; DUNE Collaboration

2016-03-01

The 35-ton prototype for the Deep Underground Neutrino Experiment (DUNE) Far Detector is a single-phase liquid argon time projection chamber (LAr-TPC) integrated detector that will take cosmics data for a two month run beginning in February 2016. The 35-ton prototype will characterize DUNE's Far Detector technology performance and provide a sample of real data for DUNE reconstruction algorithms. The 35-ton prototype has two drift volumes of lengths 2.23 m and 0.23 m on either side of its anode plane assembly (APA) and makes use of wire planes with wrapped wires and a photon detection system (PDS) utilizing photon detection panels read out by silicon photomultipliers (SiPMs). Data from the 35-ton LAr detector are expected to provide rich information on scintillation light and charged particle tracks. We present a preliminary analysis of cosmics data taken with the 35-ton detector with a focus on stopping muons.

A Nano-Thin Film-Based Prototype QCM Sensor Array for Monitoring Human Breath and Respiratory Patterns

PubMed Central

Selyanchyn, Roman; Wakamatsu, Shunichi; Hayashi, Kenshi; Lee, Seung-Woo

2015-01-01

Quartz crystal microbalance (QCM) sensor array was developed for multi-purpose human respiration assessment. The sensor system was designed to provide feedback for human respiration. Thorough optimization of measurement conditions: air flow, temperature in the QCM chamber, frequency measurement rate, and electrode position regarding to the gas flow—was performed. As shown, acquisition of respiratory parameters (rate and respiratory pattern) could be achieved even with a single electrode used in the system. The prototype system contains eight available QCM channels that can be potentially used for selective responses to certain breath chemicals. At present, the prototype machine is ready for the assessment of respiratory functions in larger populations in order to gain statistical validation. To the best of our knowledge, the developed prototype is the only respiratory assessment system based on surface modified QCM sensors. PMID:26263994

Sequential Notch activation regulates ventricular chamber development

PubMed Central

D'Amato, Gaetano; Luxán, Guillermo; del Monte-Nieto, Gonzalo; Martínez-Poveda, Beatriz; Torroja, Carlos; Walter, Wencke; Bochter, Matthew S.; Benedito, Rui; Cole, Susan; Martinez, Fernando; Hadjantonakis, Anna-Katerina; Uemura, Akiyoshi; Jiménez-Borreguero, Luis J.; de la Pompa, José Luis

2016-01-01

Ventricular chambers are essential for the rhythmic contraction and relaxation occurring in every heartbeat throughout life. Congenital abnormalities in ventricular chamber formation cause severe human heart defects. How the early trabecular meshwork of myocardial fibres forms and subsequently develops into mature chambers is poorly understood. We show that Notch signalling first connects chamber endocardium and myocardium to sustain trabeculation, and later coordinates ventricular patterning and compaction with coronary vessel development to generate the mature chamber, through a temporal sequence of ligand signalling determined by the glycosyltransferase manic fringe (MFng). Early endocardial expression of MFng promotes Dll4–Notch1 signalling, which induces trabeculation in the developing ventricle. Ventricular maturation and compaction require MFng and Dll4 downregulation in the endocardium, which allows myocardial Jag1 and Jag2 signalling to Notch1 in this tissue. Perturbation of this signalling equilibrium severely disrupts heart chamber formation. Our results open a new research avenue into the pathogenesis of cardiomyopathies. PMID:26641715

Ultrasonic corona sensor study

NASA Technical Reports Server (NTRS)

Harrold, R. T.

1976-01-01

The overall objective of this program is to determine the feasibility of using ultrasonic (above 20 kHz) corona detection techniques to detect low order (non-arcing) coronas in varying degrees of vacuum within large high vacuum test chambers, and to design, fabricate, and deliver a prototype ultrasonic corona sensor.

77 FR 65405 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-26

... Munoz Rivera St., Aguas Buenas, 12000934 Florida Municipality De Luxe Florida, (Early Prototypes for... Corporation, (Early Prototypes for Manufacturing Plants in Puerto Rico, 1948-1958 MPS) PR 992, KM 0.3...

Utilization of natural and supplemental biofuels for harvesting energy from marine sediments

NASA Astrophysics Data System (ADS)

Nielsen, Mark E.

A benthic microbial fuel cell (BMFC) is an electrochemical device that generates current from the redox gradient at the sediment-water interface. Early prototypes had anodes buried in anoxic sediments and cathodes in overlying water. The BMFCs described in this dissertation are based on a chamber design that enables the use of high surface-area fiber electrodes and facilitates enhanced mass transport to the anode. Results from Yaquina Bay, OR, show that mass transport resistance accounted for at least 93% of the total internal resistance for a particular BMFC configuration. Power output was increased 18-fold by mechanically induced fluid transport through the anode chamber. At a cold seep in Monterey Canyon, CA, naturally driven advection resulted in a five-fold increase in power from a BMFC with low-pressure check valves relative to an identical BMFC with high-pressure check valves. Enhanced transport coincided with a change in the microbial community on the anode from one dominated by epsilonproteobacteria to one with relatively even representation from deltaproteobacteria, epsilonproteobacteria, firmicutes and flavobacterium/cytophaga/bacterioides. Laboratory experiments investigated the effect of adding supplemental carbon sources to anode chambers. Repeated lactate injections appeared to stimulate sulfate reduction resulting in short term power gains but did not apparently shift the process responsible for baseline current. When a specific inhibitor of sulfate reduction was added, lactate-supplemented and unsupplemented BMFCs performed similarly. BMFCs have been proposed as power sources for monitoring systems in remote locations. Practical implementation of this technology is governed by three conditions: (1) low-voltage current must be stepped up to meet the requirements of off-the-shelf electronic devices, (2) modest power production and variable power demands require integrated energy storage, and (3) BMFCs should be operated at the most efficient potential for energy production. A combination power converter/potentiostat/rechargeable battery system was described based on these considerations and tested with a chambered BMFC in Yaquina Bay, OR. The BMFC provided intermittent power to an acoustic receiver, and results highlight the need to increase power, make design improvements to better seal the chamber to the sediment and increase the capacity for energy storage.

Development of a Hybrid Gas Detector/Phoswich for Hard X-Ray Astronomy

NASA Technical Reports Server (NTRS)

Pimperl, M. M.; Ramsey, B. D.; Austin, R. A.; Minamitani, T.; Weisskopf, M. C.; Grindlay, J. E.; Lum, K. S. K.; Manandhar, R. P.

1994-01-01

A hybrid detector is under development for use as a balloon-borne instrument in hard x-ray astronomy. The detector provides broad band coverage by coupling an optical avalanche chamber to a phoswich. The optical avalanche chamber yields superior instrument response at low energies while the scintillator takes over at the higher energies where the gas becomes transparent: at 25 keV, the addition of the gas chamber improves the energy resolution by a factor of 2.5 and the spatial resolution by a factor of 10 as compared to the stand-alone response of the phoswich. A half-scale prototype instrument is being constructed for test purposes and to help resolve a number of design questions involving the coupling of the two components.

Phase 1 Development Testing of the Advanced Manufacturing Demonstrator Engine

NASA Technical Reports Server (NTRS)

Case, Nicholas L.; Eddleman, David E.; Calvert, Marty R.; Bullard, David B.; Martin, Michael A.; Wall, Thomas R.

2016-01-01

The Additive Manufacturing Development Breadboard Engine (BBE) is a pressure-fed liquid oxygen/pump-fed liquid hydrogen (LOX/LH2) expander cycle engine that was built and operated by NASA at Marshall Space Flight Center's East Test Area. The breadboard engine was conceived as a technology demonstrator for the additive manufacturing technologies for an advanced upper stage prototype engine. The components tested on the breadboard engine included an ablative chamber, injector, main fuel valve, turbine bypass valve, a main oxidizer valve, a mixer and the fuel turbopump. All parts minus the ablative chamber were additively manufactured. The BBE was successfully hot fire tested seven times. Data collected from the test series will be used for follow on demonstration tests with a liquid oxygen turbopump and a regeneratively cooled chamber and nozzle.

Semi-active engine mount design using auxiliary magneto-rheological fluid compliance chamber

NASA Astrophysics Data System (ADS)

Mansour, H.; Arzanpour, S.; Golnaraghi, M. F.; Parameswaran, A. M.

2011-03-01

Engine mounts are used in the automotive industry to isolate engine and chassis by reducing the noise and vibration imposed from one to the other. This paper describes modelling, simulation and design of a semi-active engine mount that is designed specifically to address the complicated vibration pattern of variable displacement engines (VDE). The ideal isolation for VDE requires the stiffness to be switchable upon cylinder activation/deactivation operating modes. In order to have a modular design, the same hydraulic engine mount components are maintained and a novel auxiliary magneto-rheological (MR) fluid chamber is developed and retrofitted inside the pumping chamber. The new compliance chamber is a controllable pressure regulator, which can effectively alter the dynamic performance of the mount. Switching between different modes happens by turning the electrical current to the MR chamber magnetic coil on and off. A model has been developed for the passive hydraulic mount and then it is extended to include the MR auxiliary chamber as well. A proof-of-concept prototype of the design has been fabricated which validates the mathematical model. The results demonstrate unique capability of the developed semi-active mount to be used for VDE application.

Clinical prototype of a plastic water-equivalent scintillating fiber dosimeter array for QA applications.

PubMed

Lacroix, Fréderic; Archambault, Louis; Gingras, Luc; Guillot, Mathieu; Beddar, A Sam; Beaulieu, Luc

2008-08-01

A clinical prototype of a scintillating fiber dosimeter array for quality assurance applications is presented. The array consists of a linear array of 29 plastic scintillation detectors embedded in a water-equivalent plastic sheet coupled to optical fibers used to guide optical photons to a charge coupled device (CCD) camera. The CCD is packaged in a light-tight, radiation-shielded housing designed for convenient transport. A custom designed connector is used to ensure reproducible mechanical positioning of the optical fibers relative to the CCD. Profile and depth dose characterization measurements are presented and show that the prototype provides excellent dose measurement reproducibility (+/-0.8%) in-field and good accuracy (+/-1.6% maximum deviation) relative to the dose measured with an IC10 ionization chamber.

Acceptance testing of the prototype electrometer for the SAMPIE flight experiment

NASA Technical Reports Server (NTRS)

Hillard, G. Barry

1992-01-01

The Solar Array Module Plasma Interaction Experiment (SAMPIE) has two key instruments at the heart of its data acquisition capability. One of these, the electrometer, is designed to measure both ion and electron current from most of the samples included in the experiment. The accuracy requirement, specified by the project's Principal Investigator, is for agreement within 10 percent with a calibrated laboratory instrument. Plasma chamber testing was performed to assess the capabilities of the prototype design. Agreement was determined to be within 2 percent for electron collection and within 3 percent for ion collection.

Small Unix data acquisition system

NASA Astrophysics Data System (ADS)

Engberg, D.; Glanzman, T.

1994-02-01

A R&D program has been established to investigate the use of Unix in the various aspects of experimental computation. Earlier R&D work investigated the basic real-time aspects of the IBMRS/6000 workstation running AIX, which claims to be a real-time operating system. The next step in this R&D is the construction of prototype data acquisition system which attempts to exercise many of the features needed in the final on-line system in a realistic situation. For this project, we have combined efforts with a team studying the use of novel cell designs and gas mixtures in a new prototype drift chamber.

The Design and Testing of the LSSIF Advanced Thermal Control System

NASA Technical Reports Server (NTRS)

Henson, Robert A.; Keller, John R.

1995-01-01

The Life Support Systems Integration Facility (LSSIF) provides a platform to design and evaluate advanced manned space systems at NASA Johnson Space Center (JSC). The LSSIF Early Human Testing Initiative requires the integration of such subsystems to enable human occupancy of the 6 meter chamber for a 90 day closed volume test. The Advanced Thermal Control System (TCS) is an important component of the integrated system by supplying coolant to the subsystems within the chamber, such as the Air Revitalization System. The TCS incorporates an advanced high efficiency, heat pump to reject waste heat from the chamber to an external sink or 'lift' temperature that emulates a Lunar environment. The heat pump is the High Lift Heat Pump, developed by Foster-Miller, Inc., and is the main test article of the TCS. The heat pump prototype utilizes a non-CFC refrigerant in a design where the thermal requirements exceed existing terrestrial technology. These operating requirements provide a unique opportunity to design and test an advanced integrated thermal system and the associated controls. The design, control, and systems integration of the heat pump and the TCS also have terrestrial technology application. This paper addresses the design of the TCS and the heat pump, along with the control scheme to fully test the heat pump. Design approaches utilized in the LSSIF TCS are promoted for implementation in terrestrial thermal systems. The results of the preliminary thermal and fluid analyses used to develop the control of the thermal systems will also be discussed. The paper includes objectives for the 90 day human test and the test setup. Finally, conclusions will be drawn and recommendations for Earth design application are submitted.

Space Suit Portable Life Support System (PLSS) 2.0 Unmanned Vacuum Environment Testing

NASA Technical Reports Server (NTRS)

Watts, Carly; Vogel, Matthew

2016-01-01

For the first time in more than 30 years, an advanced space suit Portable Life Support System (PLSS) design was operated inside a vacuum chamber representative of the flight operating environment. The test article, PLSS 2.0, was the second system-level integrated prototype of the advanced PLSS design, following the PLSS 1.0 Breadboard that was developed and tested throughout 2011. Whereas PLSS 1.0 included five technology development components with the balance the system simulated using commercial-off-the-shelf items, PLSS 2.0 featured first generation or later prototypes for all components less instrumentation, tubing and fittings. Developed throughout 2012, PLSS 2.0 was the first attempt to package the system into a flight-like representative volume. PLSS 2.0 testing included an extensive functional evaluation known as Pre-Installation Acceptance (PIA) testing, Human-in-the-Loop testing in which the PLSS 2.0 prototype was integrated via umbilicals to a manned prototype space suit for 19 two-hour simulated EVAs, and unmanned vacuum environment testing. Unmanned vacuum environment testing took place from 1/9/15-7/9/15 with PLSS 2.0 located inside a vacuum chamber. Test sequences included performance mapping of several components, carbon dioxide removal evaluations at simulated intravehicular activity (IVA) conditions, a regulator pressure schedule assessment, and culminated with 25 simulated extravehicular activities (EVAs). During the unmanned vacuum environment test series, PLSS 2.0 accumulated 378 hours of integrated testing including 291 hours of operation in a vacuum environment and 199 hours of simulated EVA time. The PLSS prototype performed nominally throughout the test series, with two notable exceptions including a pump failure and a Spacesuit Water Membrane Evaporator (SWME) leak, for which post-test failure investigations were performed. In addition to generating an extensive database of PLSS 2.0 performance data, achievements included requirements and operational concepts verification, as well as demonstration of vehicular interfaces, consumables sizing and recharge, and water quality control.

High vacuum tip-enhanced Raman spectroscope based on a scanning tunneling microscope.

PubMed

Fang, Yurui; Zhang, Zhenglong; Sun, Mengtao

2016-03-01

In this paper, we present the construction of a high-vacuum tip-enhanced Raman spectroscopy (HV-TERS) system that allows in situ sample preparation and measurement. A detailed description of the prototype instrument is presented with experimental validation of its use and novel ex situ experimental results using the HV-TERS system. The HV-TERS system includes three chambers held under a 10(-7) Pa vacuum. The three chambers are an analysis chamber, a sample preparation chamber, and a fast loading chamber. The analysis chamber is the core chamber and contains a scanning tunneling microscope (STM) and a Raman detector coupled with a 50 × 0.5 numerical aperture objective. The sample preparation chamber is used to produce single-crystalline metal and sub-monolayer molecular films by molecular beam epitaxy. The fast loading chamber allows ex situ preparation of samples for HV-TERS analysis. Atomic resolution can be achieved by the STM on highly ordered pyrolytic graphite. We demonstrate the measurement of localized temperature using the Stokes and anti-Stokes TERS signals from a monolayer of 1,2-benzenedithiol on a gold film using a gold tip. Additionally, plasmonic catalysis can be monitored label-free at the nanoscale using our device. Moreover, the HV-TERS experiments show simultaneously activated infrared and Raman vibrational modes, Fermi resonance, and some other non-linear effects that are not observed in atmospheric TERS experiments. The high spatial and spectral resolution and pure environment of high vacuum are beneficial for basic surface studies.

Friction Stir Welding of GR-Cop 84 for Combustion Chamber Liners

NASA Technical Reports Server (NTRS)

Russell, Carolyn K.; Carter, Robert; Ellis, David L.; Goudy, Richard

2004-01-01

GRCop-84 is a copper-chromium-niobium alloy developed by the Glenn Research Center for liquid rocket engine combustion chamber liners. GRCop-84 exhibits superior properties over conventional copper-base alloys in a liquid hydrogen-oxygen operating environment. The Next Generation Launch Technology program has funded a program to demonstrate scale-up production capabilities of GR-Cop 84 to levels suitable for main combustion chamber production for the prototype rocket engine. This paper describes a novel method of manufacturing the main combustion chamber liner. The process consists of several steps: extrude the GR-Cop 84 powder into billets, roll the billets into plates, bump form the plates into cylinder halves and friction stir weld the halves into a cylinder. The cylinder is then metal spun formed to near net liner dimensions followed by finish machining to the final configuration. This paper describes the friction stir weld process development including tooling and non-destructive inspection techniques, culminating in the successful production of a liner preform completed through spin forming.

Implementation of Autonomous Control Technology for Plant Growth Chambers

NASA Technical Reports Server (NTRS)

Costello, Thomas A.; Sager, John C.; Krumins, Valdis; Wheeler, Raymond M.

2002-01-01

The Kennedy Space Center has significant infrastructure for research using controlled environment plant growth chambers. Such research supports development of bioregenerative life support technology for long-term space missions. Most of the existing chambers in Hangar L and Little L will be moved to the new Space Experiment Research and Processing Laboratory (SERPL) in the summer of 2003. The impending move has created an opportunity to update the control system technologies to allow for greater flexibility, less labor for set-up and maintenance, better diagnostics, better reliability and easier data retrieval. Part of these improvements can be realized using hardware which communicates through an ethernet connection to a central computer for supervisory control but can be operated independently of the computer during routine run-time. Both the hardware and software functionality of an envisioned system were tested on a prototype plant growth chamber (CEC-4) in Hangar L. Based upon these tests, recommendations for hardware and software selection and system design for implementation in SERPL are included.

Improved Materials for Composite and Adhesive Joints.

DTIC Science & Technology

1984-07-01

Instron or Satec environmental chambers. Development work was initiated on a prototype iso- dynamic extensometer and calibration fixture for the testing of...63 PL I ES > 0.0 0.0 1 2 + 90.0 90.0 1 X 45.0 45.0 1 -45.0 1 -E -0 04 0. 20.02 -0.03- HOFFMAN CRITERIR

Design and fabrication of prototype 6×6 cm 2 microchannel plate photodetector with bialkali photocathode for fast timing applications

DOE Office of Scientific and Technical Information (OSTI.GOV)

Xie, Junqi; Byrum, Karen; Demarteau, Marcel

Planar microchannel plate-based photodetector with bialkali photocathode is capable of fast and accurate time and position resolutions. A new 6 cm x 6 cm photodetector production facility was designed and built at Argonne National Laboratory. Small form-factor MCP-based photodetectors completely constructed of glass were designed and prototypes were successfully fabricated. Knudsen effusion cells were incorporated in the photocathode growth chamber to achieve uniform and high quantum efficiency hotocathodes. The thin film uniformity distribution was simulated and measured for an antimony film deposition, showing uniformity of better than 10%. Several prototype devices with bialkali photocathodes have been fabricated with the describedmore » system and their characteristics were evaluated in the large signal (multi-PE) limit. A typical prototype device exhibits time-of-flight resolution of ~ 27 psec and differential time resolution of ~ 9 psec, corresponding to spatial resolution of ~ 0.65 mm.« less

RaPToRS Sample Delivery System

NASA Astrophysics Data System (ADS)

Henchen, Robert; Shibata, Kye; Krieger, Michael; Pogozelski, Edward; Padalino, Stephen; Glebov, Vladimir; Sangster, Craig

2010-11-01

At various labs (NIF, LLE, NRL), activated material samples are used to measure reaction properties. The Rapid Pneumatic Transport of Radioactive Samples (RaPToRS) system quickly and safely moves these radioactive samples through a closed PVC tube via airflow. The carrier travels from the reaction chamber to the control and analysis station, pneumatically braking at the outlet. A reversible multiplexer routes samples from various locations near the shot chamber to the analysis station. Also, the multiplexer allows users to remotely load unactivated samples without manually approaching the reaction chamber. All elements of the system (pneumatic drivers, flow control valves, optical position sensors, multiplexers, Geiger counters, and release gates at the analysis station) can be controlled manually or automatically using a custom LabVIEW interface. A prototype is currently operating at NRL in Washington DC. Prospective facilities for Raptors systems include LLE and NIF.

Testing reflective insulation for improvement of buildings energy efficiency

NASA Astrophysics Data System (ADS)

Vrachopoulos, Michalis Gr.; Koukou, Maria K.; Stavlas, Dimitris G.; Stamatopoulos, Vasilis N.; Gonidis, Achilleas F.; Kravvaritis, Eleftherios D.

2012-03-01

Reflective insulation stands as an alternative to common building materials used to reduce a building's heating and cooling loads. In this work, an experimental prototype chamber facility has been designed and constructed at the campus of the Technological Educational Institution of Halkida, located in an area of climatic zone B in Greece, aiming to the evaluation of reflective insulation's performance. Reflective insulation is a part of the test room wall construction, specifically, heat insulation material of the vertical wall construction all directions (North, South, East, West), and temperature and water proofing element of the roof. Measurements were obtained for both winter and summer periods. Results indicate that the existence of reflective insulation during summer period averts the overheating at the interior of the experimental chamber, while during winter the heat is retained in the chamber.

An Apparatus to Deliver Mannitol Powder for Bronchial Provocation in Children Under Six Years Old.

PubMed

Tang, Patricia; Leung, Sharon S Y; Hor, Eleanor; Ruzycki, Conor A; Carrigy, Nicholas B; Finlay, Warren H; Brannan, John D; Devadason, Sunalene; Anderson, Sandra D; Sly, Peter D; Samnick, Kevin; Chan, Hak-Kim

2015-12-01

Currently bronchial provocation testing (BPT) using mannitol powder cannot be performed in children under 6 years. A primary reason is it is challenging for children at this age to generate a consistent inspiratory effort to inhale mannitol efficiently from a dry powder inhaler. A prototype system, which does not require any inhalation training from the pediatric subject, is reported here. It uses an external source of compressed air to disperse mannitol powder into a commercial holding chamber. Then the subject uses tidal breathing to inhale the aerosol. The setup consists of a commercially available powder disperser and Volumatic™ holding chamber. Taguchi experimental design was used to identify the effect of dispersion parameters (flow rate of compressed air, time compressed air is applied, mass of powder, and the time between dispersion and inhalation) on the fine particle dose (FPD). The prototype was tested in vitro using a USP throat connected to a next generation impactor. The aerosols from the holding chamber were drawn at 10 L/min. A scaling factor for estimating the provoking dose to induce a 15% reduction in forced expiratory volume in 1 second (FEV1) (PD15) was calculated using anatomical dimensions of the human respiratory tract at various ages combined with known dosing values from the adult BPT. Consistent and doubling FPDs were successfully generated based on the Taguchi experimental design. The FPD was reliable over a range of 0.8 (±0.09) mg to 14 (±0.94) mg. The calculated PD15 for children aged 1-6 years ranged from 7.1-30 mg. The FPDs generated from the proposed set up are lower than the calculated PD15 and therefore are not expected to cause sudden bronchoconstriction. A prototype aerosol delivery system has been developed that is consistently able to deliver doubling doses suitable for bronchial provocation testing in young children.

The LUX prototype detector: Heat exchanger development

DOE PAGES

Akerib, D. S.; Bai, X.; Bedikian, S.; ...

2013-01-24

The LUX (large underground xenon) detector is a two-phase xenon time projection chamber (TPC) designed to search for WIMP–nucleon dark matter interactions. As with all noble element detectors, continuous purification of the detector medium is essential to produce a large (> 1 ms) electron lifetime; this is necessary for efficient measurement of the electron signal which in turn is essential for achieving robust discrimination of signal from background events. Here, we describe the development of a novel purification system deployed in a prototype detector. The results from the operation of this prototype indicated heat exchange with an efficiency above 94%more » up to a flow rate of 42 slpm, allowing for an electron drift length greater than 1 m to be achieved in approximately 2 days and sustained for the duration of the testing period.« less

Novel Cyclotron-Based Radiometal Production

DOE Office of Scientific and Technical Information (OSTI.GOV)

DeGrado, Timothy R.

2013-10-31

Accomplishments: (1) Construction of prototype solution target for radiometal production; (2) Testing of prototype target for production of following isotopes: a. Zr-89. Investigation of Zr-89 production from Y-89 nitrate solution. i. Defined problems of gas evolution and salt precipitation. ii. Solved problem of precipitation by addition of nitric acid. iii. Solved gas evolution problem with addition of backpressure regulator and constant degassing of target during irradiations. iv. Investigated effects of Y-89 nitrate concentration and beam current. v. Published abstracts at SNM and ISRS meetings; (3) Design of 2nd generation radiometal solution target. a. Included reflux chamber and smaller target volumemore » to conserve precious target materials. b. Included aluminum for prototype and tantalum for working model. c. Included greater varicosities for improved heat transfer; and, (4) Construction of 2nd generation radiometal solution target started.« less

Cryogenic and radiation hard ASIC design for large format NIR/SWIR detector

NASA Astrophysics Data System (ADS)

Gao, Peng; Dupont, Benoit; Dierickx, Bart; Müller, Eric; Verbruggen, Geert; Gielis, Stijn; Valvekens, Ramses

2014-10-01

An ASIC is developed to control and data quantization for large format NIR/SWIR detector arrays. Both cryogenic and space radiation environment issue are considered during the design. Therefore it can be integrated in the cryogenic chamber, which reduces significantly the vast amount of long wires going in and out the cryogenic chamber, i.e. benefits EMI and noise concerns, as well as the power consumption of cooling system and interfacing circuits. In this paper, we will describe the development of this prototype ASIC for image sensor driving and signal processing as well as the testing in both room and cryogenic temperature.

Methods for study of cardiovascular adaptation of small laboratory animals during exposure to altered gravity. [hypothermia for cardiovascular control and cancer therapy

NASA Technical Reports Server (NTRS)

Popovic, V.

1973-01-01

Several new techniques are reported for studying cardiovascular circulation in small laboratory animals kept in metabolic chambers. Chronical cannulation, miniaturized membrane type heart-lung machines, a prototype walking chamber, and a fluorocarbon immersion method to simulate weightlessness are outlined. Differential hypothermia work on rat cancers provides localized embedding of radionuclides and other chemotherapeutical agents in tumors and increases at the same time blood circulation through the warmed tumor as compared to the rest of the cold body. Some successful clinical applications of combined chemotherapy and differential hypothermia in skin cancer, mammary tumors, and brain gliomas are described.

Fiber optic lighting system for plant production

NASA Astrophysics Data System (ADS)

St. George, Dennis R.; Feddes, John J. R.

1991-02-01

Dennis St. George John Feddes (Dept. of Agricultural Engineering University of Alberta Edmonton AB Canada T6G 2Hl) A prototype light collection and transmission device was developed and evaluated for the potential of irradiating plants grown in an opague growth chamber. Results indicated that the device transmitted light with a photon flux of 130 1amol/s/m2 (4000-7000 nm) to the bottom of the growth chamber when direct solar radiation was 800 W/m2 (300-2500 nm) outside. The overall collection and transmission efficiency for photosynthetically active radiation is 19. 2. A growth trial with plants indicated that artificial lighting is required during cloudy periods. 1.

Effect of a chamber orchestra on direct sound and early reflections for performers on stage: A boundary element method study.

PubMed

Panton, Lilyan; Holloway, Damien; Cabrera, Densil

2017-04-01

Early reflections are known to be important to musicians performing on stage, but acoustic measurements are usually made on empty stages. This work investigates how a chamber orchestra setup on stage affects early reflections from the stage enclosure. A boundary element method (BEM) model of a chamber orchestra is validated against full scale measurements with seated and standing subjects in an anechoic chamber and against auditorium measurements, demonstrating that the BEM simulation gives realistic results. Using the validated BEM model, an investigation of how a chamber orchestra attenuates and scatters both the direct sound and the first-order reflections is presented for two different sized "shoe-box" stage enclosures. The first-order reflections from the stage are investigated individually: at and above the 250 Hz band, horizontal reflections from stage walls are attenuated to varying degrees, while the ceiling reflection is relatively unaffected. Considering the overall effect of the chamber orchestra on the direct sound and first-order reflections, differences of 2-5 dB occur in the 1000 Hz octave band when the ceiling reflection is excluded (slightly reduced when including the unobstructed ceiling reflection). A tilted side wall case showed the orchestra has a reduced effect with a small elevation of the lateral reflections.

Designing an Active Target Test Projection Chamber

NASA Astrophysics Data System (ADS)

Koci, James; Tan Ahn Collaboration, Dr.; Nicolas Dixneuf Collaboration

2015-10-01

The development of instrumentation in nuclear physics is crucial for advancing our ability to measure the properties of exotic nuclei. One limitation of the use of exotic nuclei in experiment is their very low production intensities. Recently, detectors, called active-target dectectors, have been developed to address this issue. Active-target detectors use a gas medium to image charged-particle tracks that are emitted in nuclear reactions. Last semester, I designed a vacuum chamber to be used in developing Micro-Pattern Gas detectors that will upgrade the capabilities of an active-target detector called the Prototype AT-TPC. With the exterior of the chamber complete, I have now been using an electric field modeling program, Garfield, developed by CERN to design a field cage to be placed within the vacuum chamber. The field cage will be a box-like apparatus consisting of two parallel metal plates connected with a resistor chain and attached to wires wrapped between them. The cage will provide a uniform electric field within the chamber to drift electrons from nuclear reactions down to the detector in the bottom of the chamber. These signals are then amplified by a proportional counter, and the data is sent to a computer. For the long term, we would like to incorporate a Micro-Pattern Gas Detectors in the interior of the chamber and eventually use the AT-TPC to examine various nuclei. Dr. Ahn is my advising professor.

Numerical analysis of the transient flow in a scroll refrigeration compressor

NASA Astrophysics Data System (ADS)

Sun, Shuaihui; Wu, Kai; Guo, Pengcheng; Luo, Xingqi

2017-08-01

In the present paper, the CFD technology is adopted to simulate the working process of a scroll refrigeration compressor with R22 as working fluid. The structural grids in the scroll compressor were updated continually during the solving process to cope with the movement boundaries of the fluid domain. The radial meshing clearance was 0.008 mm which was the same with that in the real prototype. The pressure, velocity and temperature distribution in chambers of compressor were computed. Also, the transient mass flux diagrams were calculated out. The results indicated that the pressure was asymmetrical in the two symmetrical suction chambers, because the suction port and passage were not absolutely symmetrical. The gradient of temperature was great in each working chamber due to leakage flow. Velocity vector distribution was asymmetrical in each pair of working chamber owing to the movement of orbiting scroll; the flow was complicated in the central working chamber. The movement of the orbiting scroll had different influence on the vortexes formation in each pair of compression chamber. The inlet and outlet mass flux fluctuated with the crank angle obviously. Because of the ‘cut-off’ of the refrigeration fluid in the suction chamber when the crank angle was larger than 220°, the inlet mass flux decreased remarkably. Finally, some useful advices were given to improve the performance of the scroll refrigeration compressor.

Hot section viewing system

NASA Technical Reports Server (NTRS)

Morey, W. W.

1983-01-01

The objective of the hot section viewing program is to develop a prototype optical system for viewing the interior of a gas turbine combustor during high temperature, high pressure operation in order to produce a visual record of some causes of premature hot section failures. The program began by identifying and analyzing system designs that would provide clearest images while being able to survive the hostile environment inside the combustion chamber. Different illumination methods and computer techniques for image enhancement and analysis were examined during a preliminary test phase. In the final phase of the program the prototype system was designed and fabricated and is currently being tested on a high pressure combustor rig.

Commercial Absorption Heat Pump Water Heater: Beta Prototype Evaluation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Geoghegan, Patrick; Ally, Moonis; Sharma, Vishaldeep

2016-10-14

The Beta version of the Commercial Absorption Heat Pump (CAHP) water heater was evaluated in the environmental chambers at Oak Ridge National Laboratory. Ambient air conditions ranged from 17 to 75 oF and inlet water temperatures ranged from 100 to 120oF in order to capture trends in performance. The unit was operated under full fire (100%) and partial fire (55%). The unit was found to perform at 90% of the project goal at the design conditions of 47oF ambient and 100oF water temperatures. The trends across the full range of environmental conditions were as expected for ambient air temperatures abovemore » 32oF. Below this temperature and for the full fire condition, frost accumulated on the evaporator coil. In future work a defrost strategy will be enabled, the unit will be thoroughly cleaned of an oil contamination and the rectifier will be reconfigured in order to meet the design goals and have a field test unit ready in early 2017.« less

Novice designers’ use of prototypes in engineering design

PubMed Central

Deininger, Michael; Daly, Shanna R.; Sienko, Kathleen H.; Lee, Jennifer C.

2017-01-01

Prototypes are essential tools in product design processes, but are often underutilized by novice designers. To help novice designers use prototypes more effectively, we must first determine how they currently use prototypes. In this paper, we describe how novice designers conceptualized prototypes and reported using them throughout a design project, and compare reported prototyping use to prototyping best practices. We found that some of the reported prototyping practices by novice designers, such as using inexpensive prototypes early and using prototypes to define user requirements, occurred infrequently and lacked intentionality. Participants’ initial descriptions of prototypes were less sophisticated than how they later described using them and only upon prompted reflection did participants recognize more specific benefits of using prototypes. PMID:29398740

High vacuum tip-enhanced Raman spectroscope based on a scanning tunneling microscope

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fang, Yurui; Bionanophotonics, Department of Applied Physics, Chalmers University of Technology, Göteborg, SE 41296; Zhang, Zhenglong

2016-03-15

In this paper, we present the construction of a high-vacuum tip-enhanced Raman spectroscopy (HV-TERS) system that allows in situ sample preparation and measurement. A detailed description of the prototype instrument is presented with experimental validation of its use and novel ex situ experimental results using the HV-TERS system. The HV-TERS system includes three chambers held under a 10{sup −7} Pa vacuum. The three chambers are an analysis chamber, a sample preparation chamber, and a fast loading chamber. The analysis chamber is the core chamber and contains a scanning tunneling microscope (STM) and a Raman detector coupled with a 50 ×more » 0.5 numerical aperture objective. The sample preparation chamber is used to produce single-crystalline metal and sub-monolayer molecular films by molecular beam epitaxy. The fast loading chamber allows ex situ preparation of samples for HV-TERS analysis. Atomic resolution can be achieved by the STM on highly ordered pyrolytic graphite. We demonstrate the measurement of localized temperature using the Stokes and anti-Stokes TERS signals from a monolayer of 1,2-benzenedithiol on a gold film using a gold tip. Additionally, plasmonic catalysis can be monitored label-free at the nanoscale using our device. Moreover, the HV-TERS experiments show simultaneously activated infrared and Raman vibrational modes, Fermi resonance, and some other non-linear effects that are not observed in atmospheric TERS experiments. The high spatial and spectral resolution and pure environment of high vacuum are beneficial for basic surface studies.« less

Design of prototype charged particle fog dispersal unit

NASA Technical Reports Server (NTRS)

Collins, F. G.; Frost, W.; Kessel, P.

1981-01-01

The unit was designed to be easily modified so that certain features that influence the output current and particle size distribution could be examined. An experimental program was designed to measure the performance of the unit. The program described includes measurements in a fog chamber and in the field. Features of the nozzle and estimated nozzle characteristics are presented.

Design and development of a prototype wet oxidation system for the reclamation of water and the disposition of waste residues onboard space vehicles

NASA Technical Reports Server (NTRS)

Jagow, R. B.

1972-01-01

Laboratory investigations to define optimum process conditions for oxidation of fecal/urine slurries were conducted in a one-liter batch reactor. The results of these tests formed the basis for the design, fabrication, and testing of an initial prototype system, including a 100-hour design verification test. Areas of further development were identified during this test. Development of a high pressure slurry pump, materials corrosion studies, oxygen supply trade studies, comparison of salt removal water recovery devices, ammonia removal investigation, development of a solids grinder, reactor design studies and bearing life tests, and development of shutoff valves and a back pressure regulator were undertaken. The development work has progressed to the point where a prototype system suitable for manned chamber testing can be fabricated and tested with a high degree of confidence of success.

Construction of the DHCAL

NASA Astrophysics Data System (ADS)

Francis, Kurt; CALICE Collaboration

Particle Flow Algorithms (PFAs) have been proposed as a method of improving the jet energy resolution of future colliding beam detectors. PFAs require calorimeters with high granularity to enable three-dimensional imaging of events. The Calorimeter for the Linear Collider Collaboration (CALICE) is developing and testing prototypes of such highly segmented calorimeters. In this context, a large prototype of a Digital Hadron Calorimeter (DHCAL) was developed and constructed by a group led by Argonne National Laboratory. The DHCAL consists of 52 layers, instrumented with Resistive Plate Chambers (RPCs) and interleaved with steel absorber plates. The RPCs are read out by 1 x 1 cm2 pads with a 1-bit resolution (digital readout). The DHCAL prototype has approximately 480,000 readout channels. This talk reports on the design, construction and commissioning of the DHCAL. The DHCAL was installed at the Fermilab Test Beam Facility in fall 2010 and data was collected through the summer 2011.

The scanning cryomacroscope - A device prototype for the study of cryopreservation

NASA Astrophysics Data System (ADS)

Feig, Justin S. G.; Rabin, Yoed

2014-07-01

A new cryomacroscope prototype-a visualization device for the in situ analysis of cryopreserved biological samples-is presented in the current study. In order to visualize samples larger than the field of view of the optical setup, a scanning mechanism is integrated into the system, which represents a key improvement over previous cryomacroscope prototypes. Another key feature of the new design is in its compatibility with available top-loading controlled-rate cooling chambers, which eliminates the need for a dedicated cooling mechanism. The objective for the current development is to create means to generate a single digital movie of an experimental investigation, with all relevant data overlaid. The visualization capabilities of the scanning cryomacroscope are demonstrated in the current study on the cryoprotective agent dimethyl sulfoxide and the cryoprotective cocktail DP6. Demonstrated effects include glass formation, various regimes of crystallization, thermal contraction, and fracture formation.

Assessing the add value of ensemble forecast in a drought early warning

NASA Astrophysics Data System (ADS)

Calmanti, Sandro; Bosi, Lorenzo; Fernandez, Jesus; De Felice, Matteo

2015-04-01

The EU-FP7 project EUPORIAS is developing a prototype climate service to enhance the existing food security drought early warning system in Ethiopia. The Livelihoods, Early Assessment and Protection (LEAP) system is the Government of Ethiopia's national food security early warning system, established with the support of WFP and the World Bank in 2008. LEAP was designed to increase the predictability and timeliness of response to drought-related food crises in Ethiopia. It combines early warning with contingency planning and contingency funding, to allow the government, WFP and other partners to provide early assistance in anticipation of an impending catastrophes. Currently, LEAP uses satellite based rainfall estimates to monitor drought conditions and to compute needs. The main aim of the prototype is to use seasonal hindcast data to assess the added value of using ensemble climate rainfall forecasts to estimate the cost of assistance of population hit by major droughts. We outline the decision making process that is informed by the prototype climate service, and we discuss the analysis of the expected and skill of the available rainfall forecast data over Ethiopia. One critical outcome of this analysis is the strong dependence of the expected skill on the observational estimate assumed as reference. A preliminary evaluation of the full prototype products (drought indices and needs estimated) using hindcasts data will also be presented.

Testing fireproof materials in a combustion chamber

NASA Astrophysics Data System (ADS)

Kulhavy, Petr; Martinec, Tomas; Novak, Ondrej; Petru, Michal; Srb, Pavel

This article deals with a prototype concept, real experiment and numerical simulation of a combustion chamber, designed for testing fire resistance some new insulating composite materials. This concept of a device used for testing various materials, providing possibility of monitoring temperatures during controlled gas combustion. As a fuel for the combustion process propane butane mixture has been used and also several kinds of burners with various conditions of inlet air (forced, free) and fuel flows were tested. The tested samples were layered sandwich materials based on various materials or foams, used as fillers in fire shutters. The temperature distribution was measured by using thermocouples. A simulation of whole concept of experimental chamber has been carried out as the non-premixed combustion process in the commercial final volume sw Pyrosim. The result was to design chamber with a construction suitable, according to the international standards, achieve the required values (temperature in time). Model of the combustion based on a stoichiometric defined mixture of gas and the tested layered samples showed good conformity with experimental results - i.e. thermal distribution inside and heat release rate that has gone through the sample.

Development of in-vessel components of the microfission chamber for ITER.

PubMed

Ishikawa, M; Kondoh, T; Ookawa, K; Fujita, K; Yamauchi, M; Hayakawa, A; Nishitani, T; Kusama, Y

2010-10-01

Microfission chambers (MFCs) will measure the total neutron source strength in ITER. The MFCs will be installed behind blanket modules in the vacuum vessel (VV). Triaxial mineral insulated (MI) cables will carry signals from the MFCs. The joint connecting triaxial MI cables in the VV must be considered because the MFCs and the MI cables will be installed separately at different times. Vacuum tight triaxial connector of the MI cable has been designed and a prototype has been constructed. Performance tests indicate that the connector can be applied to the ITER environment. A small bending-radius test of the MI cable indicates no observed damage at a curvature radius of 100 mm.

Recent Results on Gridpix Detectors:. AN Integrated Micromegas Grid and a Micromegas Ageing Test

NASA Astrophysics Data System (ADS)

Chefdeville, M.; Aarts, A.; van der Graaf, H.; van der Putten, S.

2006-04-01

A new gas-filled detector combining a Micromegas with a CMOS pixel chip has been recently tested. A procedure to integrate the Micromegas grid onto silicon wafers (‘wafer post processing’) has been developed. We aim to eventually integrate the grid on top of wafers of CMOS pixel chips. The first part of this contribution describes an application in vertex detection (GOSSIP). Then tests of the first detector prototype of a grid integrated on a bare silicon wafer are shown. Finally an ageing test of a Micromegas chamber is presented. After verifying the chambers' proportionality at a very high dose rates, the device was irradiated until ageing became apparent.

Development of in-vessel components of the microfission chamber for ITER1

PubMed Central

Ishikawa, M.; Kondoh, T.; Ookawa, K.; Fujita, K.; Yamauchi, M.; Hayakawa, A.; Nishitani, T.; Kusama, Y.

2010-01-01

Microfission chambers (MFCs) will measure the total neutron source strength in ITER. The MFCs will be installed behind blanket modules in the vacuum vessel (VV). Triaxial mineral insulated (MI) cables will carry signals from the MFCs. The joint connecting triaxial MI cables in the VV must be considered because the MFCs and the MI cables will be installed separately at different times. Vacuum tight triaxial connector of the MI cable has been designed and a prototype has been constructed. Performance tests indicate that the connector can be applied to the ITER environment. A small bending-radius test of the MI cable indicates no observed damage at a curvature radius of 100 mm. PMID:21033834

Performance of timing Resistive Plate Chambers with protons from 200 to 800 MeV

NASA Astrophysics Data System (ADS)

Machado, J.; Adamczewski-Musch, J.; Blanco, A.; Boretzky, K.; Cabanelas, P.; Cartegni, L.; Ferreira Marques, R.; Fonte, P.; Fruehauf, J.; Galaviz, D.; Heil, M.; Henriques, A.; . Ickert, G.; Körper, D.; Lopes, L.; Palka, M.; Pereira, A.; Rossi, D.; Simon, H.; Teubig, P.; Traxler, M.; Velho, P.; Altstadt, S.; Atar, L.; Aumann, T.; Bemmerer, D.; Caesar, C.; Charpy, A.; Elekes, Z.; Fiori, E.; Gasparic, I.; Gerbig, J.; Göbel, K.; Heftrich, T.; Heine, M.; Heinz, A.; Holl, M.; Ignatov, A.; Isaak, J.; Johansson, H.; Kelic-Heil, A.; Lederer, C.; Lindberg, S.; Löher, B.; Marganiec, J.; Martensson, M.; Nilsson, T.; Panin, V.; Paschalis, S.; Petri, M.; Plag, R.; Pohl, M.; Rastrepina, G.; Reifarth, R.; Reinhardt, T. P.; Röder, M.; Savran, D.; Scheit, H.; Schrock, P.; Silva, J.; Stach, D.; Strannerdahl, F.; Thies, R.; Wagner, A.; Wamers, F.; Weigand, M.

2015-01-01

A prototype composed of four resistive plate chamber layers has been exposed to quasi-monoenergetic protons produced from a deuteron beam of varying energy (200 to 800 AMeV) in experiment S406 at GSI, Darmstadt, Germany. The aim of the experiment is to characterize the response of the prototype to protons in this energy range, which deposit from 1.75 to 6 times more energy than minimum ionizing particles. Each layer, with an active area of about 2000 × 500 mm2, is made of modules containing the active gaps, all in multigap construction. Each gap is defined by 0.3 mm nylon mono-filaments positioned between 2.85 mm thick float glass electrodes. The modules are operated in avalanche mode with a non-flammable gas mixture composed of 90% C2H2F4 and 10% SF6. The signals are readout by a pick-up electrode formed by 15 copper strips (per layer), spaced at a pitch of 30 mm, connected at both sides to timing front end electronics. Results show an uniform efficiency close to 100% along with a timing resolution of around 60 ps on the entire 2000 × 500 mm2 area.

Directional Dark Matter Detector Prototype (Time Projection Chamber)

NASA Astrophysics Data System (ADS)

Oliver-Mallory, Kelsey; Garcia-Sciveres, Maurice; Kadyk, John; Lopex-Thibodeaux, Mayra

2013-04-01

The time projection chamber is a mature technology that has emerged as a promising candidate for the directional detection of the WIMP particle. In order to utilize this technology in WIMP detection, the operational parameters must be chosen in the non-ideal regime. A prototype WIMP detector with a 10cm field cage, double GEM amplification, and ATLAS FEI3 pixel chip readout was constructed for the purpose of investigating effects of varying gas pressure in different gas mixtures. The rms radii of ionization clusters of photoelectrons caused by X-rays from a Fe-55 source were measured for several gas pressures between 760torr and 99torr in Ar(70)/ CO2(30), CF4, He(80)/Isobutane(20), and He(80)/CF4(20) mixtures. Average radii were determined from distributions of the data for each gas mixture and pressure, and revealed a negative correlation between pressure and radius in Ar(70)/CO2(30) and He(80)/Isobutane(20) mixtures. Investigation of the pressure-radius measurements are in progress using distributions of photoelectron and auger electron practical ranges (Univ. of Pisa) and diffusion, using the Garfield Monte Carlo program.

AGATE: A High Energy Gamma-Ray Telescope Using Drift Chambers

NASA Astrophysics Data System (ADS)

Mukherjee, R.; Dingus, B. L.; Esposito, J. A.; Bertsch, D. L.; Cuddapah, R.; Fichtel, C. E.; Hartman, R. C.; Hunter, S. D.; Thompson, D. J.

1996-01-01

The exciting results from the highly successful Energetic Gamma-Ray Experiment Telescope (EGRET) instrument on the Compton Gamma-Ray Observatory (CGRO) has contributed significantly to increasing our understanding of high energy gamma-ray astronomy. A follow-on mission to EGRET is needed to continue these scientific advances as well as to address the several new scientific questions raised by EGRET. Here we describe the work being done on the development of the Advanced Gamma-Ray Astronomy Telescope Experiment (AGATE), visualized as the successor to EGRET. In order to achieve the scientific goals, AGATE will have higher sensitivity than EGRET in the energy range 30 MeV to 30 GeV, larger effective area, better angular resolution, and an extended low and high energy range. In its design, AGATE will follow the tradition of the earlier gamma-ray telescopes, SAS-2, COS B, and EGRET, and will have the same four basic components of an anticoincidence system, directional coincidence system, track imaging, and energy measurement systems. However, due to its much larger size, AGATE will use drift chambers as its track imaging system rather than the spark chambers used by EGRET. Drift chambers are an obvious choice as they have less deadtime per event, better spatial resolution, and are relatively easy and inexpensive to build. Drift chambers have low power requirements, so that many layers of drift chambers can be included. To test the feasibility of using drift chambers, we have constructed a prototype instrument consisting of a stack of sixteen 1/2m × 1/2m drift chambers and have measured the spatial resolution using atmospheric muons. The results on the drift chamber performance in the laboratory are presented here.

Development of a micro-mechanical valve in a novel glaucoma implant.

PubMed

Siewert, Stefan; Schultze, Christine; Schmidt, Wolfram; Hinze, Ulf; Chichkov, Boris; Wree, Andreas; Sternberg, Katrin; Allemann, Reto; Guthoff, Rudolf; Schmitz, Klaus-Peter

2012-10-01

This paper describes methods for design, manufacturing and characterization of a micro-mechanical valve for a novel glaucoma implant. The implant is designed to drain aqueous humour from the anterior chamber of the eye into the suprachoroidal space in case of an elevated intraocular pressure (IOP). In contrast to any existing glaucoma drainage device (GDD), the valve mechanism is located in the anterior chamber and there, surrounded by aqueous humour, immune to fibrosis induced failure. For the prevention of hypotony the micro-mechanical valve is designed to open if the physiological pressure difference between the anterior chamber and the suprachoroidal space in the range of 0.8 mmHg to 3.7 mmHg is exceeded. In particular the work includes: (i) manufacturing and morphological characterization of polymer tubing, (ii) mechanical material testing as basis for (iii) the design of micro-mechanical valves using finite element analysis (FEA), (iv) manufacturing of microstent prototypes including micro-mechanical valves by femtosecond laser micromachining and (v) the experimental fluid-mechanical characterization of the manufactured microstent prototypes with regard to valve opening pressure. The considered materials polyurethane (PUR) and silicone (SIL) exhibit low elastic modulus and high extensibility. The unique valve design enables a low opening pressure of micro-mechanical valves. An ideal valve design for PUR and SIL with an experimentally determined opening pressure of 2 mmHg and 3.7 mmHg is identified. The presented valve approach is suitable for the inhibition of hypotony as a major limitation of today's GDD and will potentially improve the minimally invasive treatment of glaucoma.

SU-G-BRB-12: Polarity Effects in Small Volume Ionization Chambers in Small Fields

DOE Office of Scientific and Technical Information (OSTI.GOV)

Arora, V; Parsai, E; Mathew, D

2016-06-15

Purpose: Dosimetric quantities such as the polarity correction factor (Ppol) are important parameters for determining the absorbed dose and can influence the choice of dosimeter. Ppol has been shown to depend on beam energy, chamber design, and field size. This study is to investigate the field size and detector orientation dependence of Ppol in small fields for several commercially available micro-chambers. Methods: We evaluate the Exradin A26, Exradin A16, PTW 31014, PTW 31016, and two prototype IBA CC-01 micro-chambers in both horizontal and vertical orientations. Measurements were taken at 10cm depth and 100cm SSD in a Wellhofer BluePhantom2. Measurements weremore » made at square fields of 0.6, 0.8, 1.0, 1.2, 1.4, 2.0, 2.4, 3.0, and 5.0 cm on each side using 6MV with both ± 300VDC biases. PPol was evaluated as described in TG-51, reported using −300VDC bias for Mraw. Ratios of PPol measured in the clinical field to the reference field are presented. Results: A field size dependence of Ppol was observed for all chambers, with increased variations when mounted vertically. The maximum variation observed in PPol over all chambers mounted horizontally was <1%, and occurred at different field sizes for different chambers. Vertically mounted chambers demonstrated variations as large as 3.2%, always at the smallest field sizes. Conclusion: Large variations in Ppol were observed for vertically mounted chambers compared to horizontal mountings. Horizontal mountings demonstrated a complicated relationship between polarity variation and field size, probably relating to differing details in each chambers construction. Vertically mounted chambers consistently demonstrated the largest PPol variations for the smallest field sizes. Measurements obtained with a horizontal mounting appear to not need significant polarity corrections for relative measurements, while those obtained using a vertical mounting should be corrected for variations in PPol.« less

House hold unit for the treatment of fluoride, iron, arsenic and microorganism contaminated drinking water.

PubMed

Dhadge, Vijaykumar L; Medhi, Chitta Ranjan; Changmai, Murchana; Purkait, Mihir Kumar

2018-05-01

A first of its kind hybrid electrocoagulation-filtration prototype unit was fabricated for the removal of fluoride, iron, arsenic and microorganisms contaminated drinking water. The unit comprised of 3 chambers, chamber A consisting of an inlet for the water to be treated and an outlet for the treated water along with one block of aluminum electrodes. Chamber B consisted of ceramic membrane filtration assembly at the bottom over a metallic support which filters the flocs so produced in chamber A and chamber C consisting of space to collect the treated water. Operating parameters were maintained as current density of 625 A m -2 and an electrode distance of 0.005 m. Contaminated drinking water containing mixture of fluoride (10 mg L -1 ), iron (25 mg L -1 ), arsenic (200 μg L -1 ) and microorganisms (35 CFU ml -1 ) was used for the experiment. A removal of 98.74%, 95.65%, 93.2% and 100% were obtained for iron, arsenic, fluoride and microorganisms, respectively. The apparatus and method made it possible to efficiently treat contaminated drinking water to produce drinkable water as per WHO specification. By-products obtained from the electrocoagulation bath were analyzed using SEM, EDX and XRD and explained. Copyright © 2018 Elsevier Ltd. All rights reserved.

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

The ATLAS collaboration at LHC has chosen the Micromegas (Micro Mesh Gaseous Structure) technology along with the small-strip Thin Gap Chambers (sTGC) for the high luminosity upgrade of the inner muon station in the high-rapidity region, the so called New Small Wheel (NSW). It employs eight layers of Micromegas detectors and eight layers of sTGC. The NSW project requires fully efficient Micromegas chambers with spatial resolution down to 100 μm in the precision coordinate for momentum reconstruction, and at mm level in the azimuthal (second) coordinate, over a total active area of 1200 m{sup 2}, with a rate capability upmore » to about 15 kHz/cm{sup 2} and operation in a moderate magnetic field up to B = 0.4 T. The required tracking capability is provided by the intrinsic space resolution combined with a mechanical precision at the level of 30 μm along the precision coordinate. Together with the precise tracking capability the Micromegas chambers should provide a trigger signal. Several tests have been performed on small (10x10 cm{sup 2}) and large (1 x 1 m{sup 2}) size single gap chambers prototypes using high energy hadron beams at CERN, low and intermediate energy (0.5-5 GeV) electron beams at Frascati and DESY, neutron beams at Demokritos (Athens) and Garching (Munich) and cosmic rays. More recently two quadruplets with dimensions 1.2 x 0.5 m{sup 2} and the same configuration and structure foreseen for the NSW upgrade have been built at CERN and tested with high energy pions/muons beam. Results obtained in the most recent tests, in different configurations and operating conditions, in dependence with the magnetic field, will be presented, along with a comparison between different read-out electronics, either based on the APV25 chips, or based on a new digital front-end ASIC developed in its second version (VMM2) as a new prototype of the final chip that will be employed in the NSW upgrade. (authors)« less

The Plant Research Unit: An International Space Station Habitat

NASA Technical Reports Server (NTRS)

Morrow, Robert; Reiss-Bubenheim, Debra; Schaefer, Ronald L.

2003-01-01

The Plant Research Unit (PRU) is one of six life science habitats being developed as part of the Space Station Biological Research Program. The PRU is designed for experiments in microgravity and will utilize the ISS Centrifuge Facility to provide gravity levels between microgravity and 29. The PRU will provide and control all aspects of a plant s needs in a nearly closed system. In other words, the shoot and root environments will not be open to the astronaut s environment except for experiment maintenance such as planting, harvesting and plant sampling. This also means that all lighting, temperature and humidity control, "watering," and air filtering and cleaning .must be done within strict limitations of volume, weight, power, and crew time while at the same time providing a very high level of reliability and a service life in excess of 10 years. The PRU will contain two plant chambers 31.5 cm tall, each with independent control of temperature, humidity, light level and photoperiod, CO2 level, nutrient and water delivery, and video and data acquisition. The PRU is currently in the preliminary design phase and a number of subsystem components have been prototyped for testing, including the temperature and humidity control systems, the plant chambers, the LED lighting system, the atmospheric control system and a variety of nutrient delivery systems. The LED prototype provides independent feedback control of 5 separate spectral bands and variable output between 0 and 1000 micro-mol sq m/sec. The water and nutrient delivery system (WNDS) prototypes have been used to test particulate based, thin film, and gel-based WNDS configurations.

Temporal integration of soil N2O fluxes: validation of IPNOA station automatic chamber prototype.

PubMed

Laville, P; Bosco, S; Volpi, I; Virgili, G; Neri, S; Continanza, D; Bonari, E

2017-09-04

The assessment of nitrous oxide (N 2 O) fluxes from agricultural soil surfaces still poses a major challenge to the scientific community. The evaluations of integrated soil fluxes of N 2 O are difficult owing to their lower emissions when compared with CO 2 . These emissions are also sporadic as environmental conditions act as a limiting factor. A station prototype was developed to integrate annual N 2 O and CO 2 emissions using an automatic chamber technique and infrared spectrometers within the LIFE project (IPNOA: LIFE11 ENV/IT/00032). It was installed from June 2014 to October 2015 in an experimental maize field in Tuscany. The detection limits for the fluxes were evaluated up to 1.6 ng N-N 2 O m 2  s -1 and 0.3 μg C-CO 2  m 2  s -1 . A cross-comparison carried out in September 2015 with the "mobile IPNOA prototype"; a high-sensibility transportable instrument already validated provided evidence of very similar values and highlighted flux assessment limitations according to the gas analyzers used. The permanent monitoring device showed that temporal distribution of N 2 O fluxes can be very large and discontinuous over short periods of less than 10 days and that N 2 O fluxes were below the detection limit of the instrumentation during approximately 70% of the measurement time. The N 2 O emission factors were estimated to 1.9% in 2014 and 1.7% in 2015, within the range of IPCC assessments.

A Prototype HTML Training System for Graphic Communication Majors

ERIC Educational Resources Information Center

Runquist, Roger L.

2010-01-01

This design research demonstrates a prototype content management system capable of training graphic communication students in the creation of basic HTML web pages. The prototype serve as a method of helping students learn basic HTML structure and commands earlier in their academic careers. Exposure to the concepts of web page creation early in…

Influence of the configuration of the magnetic filter field on the discharge structure in the RF driven negative ion source prototype for fusion

NASA Astrophysics Data System (ADS)

Lishev, S.; Schiesko, L.; Wünderlich, D.; Fantz, U.

2017-08-01

The study provides results for the influence of the filter field topology on the plasma parameters in the RF prototype negative ion source for ITER NBI. A previously developed 2D fluid plasma model of the prototype source was extended towards accounting for the particles and energy losses along the magnetic field lines and the presence of a magnetic field in the driver which is the case at the BATMAN and ELISE test-beds. The effect of the magnetic field in the driver is shown for the magnetic field configuration of the prototype source (i.e. a magnetic field produced by an external magnet frame) by comparison of plasma parameters without and with the magnetic field in the driver and for different axial positions of the filter. Since the ELISE-like magnetic field (i.e. a magnetic field produced by a current flowing through the plasma grid) is a new feature planned to be installed at the BATMAN test-bed, its effect on the discharge structure was studied for different strengths of the magnetic field. The obtained results show for both configurations of the magnetic filter the same main features in the patterns of the plasma parameters in the expansion chamber: a strong axial drop of the electron temperature and the formation of a groove accompanied with accumulation of electrons in front of the plasma grid. The presence of a magnetic field in the driver has a local impact on the plasma parameters: the formation of a second groove of the electron temperature in the case of BATMAN (due to the reversed direction of the filter field in the driver) and a strong asymmetry of the electron density. Accounting for the additional losses in the third dimension suppresses the drifts across the magnetic field and, thus, the variations of the electron density in the expansion chamber are less pronounced.

A portable life support system for use in mines

NASA Technical Reports Server (NTRS)

Zeller, S. S.

1972-01-01

The portable life support system described in this paper represents a potential increase in the probability of survival for miners who are trapped underground by a fire or explosion. The habitability and life support capability of the prototype shelter have proved excellent. Development of survival chamber life support systems for wide use in coal mines is definitely within the capabilities of current technology.

Small-strip Thin Gap Chambers for the muon spectrometer upgrade of the ATLAS experiment

NASA Astrophysics Data System (ADS)

Perez Codina, E.; ATLAS Muon Collaboration

2016-07-01

The ATLAS muon system upgrade to be installed during the LHC long shutdown in 2018/19, the so-called New Small Wheel (NSW), is designed to cope with the increased instantaneous luminosity in LHC Run 3. The small-strip Thin Gap Chambers (sTGC) will provide the NSW with a fast trigger and high precision tracking. The construction protocol has been validated by test beam experiments on a full-size prototype sTGC detector, showing the performance requirements are met. The intrinsic spatial resolution for a single layer has been found to be about 45 μm for a perpendicular incident angle, and the transition region between pads has been measured to be about 4 mm.

Z-2 Prototype Space Suit Development

NASA Technical Reports Server (NTRS)

Ross, Amy; Rhodes, Richard; Graziosi, David; Jones, Bobby; Lee, Ryan; Haque, Bazle Z.; Gillespie, John W., Jr.

2014-01-01

NASA's Z-2 prototype space suit is the highest fidelity pressure garment from both hardware and systems design perspectives since the Space Shuttle Extravehicular Mobility Unit (EMU) was developed in the late 1970's. Upon completion the Z-2 will be tested in the 11 foot human-rated vacuum chamber and the Neutral Buoyancy Laboratory (NBL) at the NASA Johnson Space Center to assess the design and to determine applicability of the configuration to micro-, low- (asteroid), and planetary- (surface) gravity missions. This paper discusses the 'firsts' that the Z-2 represents. For example, the Z-2 sizes to the smallest suit scye bearing plane distance for at least the last 25 years and is being designed with the most intensive use of human models with the suit model.

A new passive radon-thoron discriminative measurement system.

PubMed

Sciocchetti, G; Sciocchetti, A; Giovannoli, P; DeFelice, P; Cardellini, F; Cotellessa, G; Pagliari, M

2010-10-01

A new passive radon-thoron discriminative measurement system has been developed for monitoring radon and thoron individually. It consists of a 'couple' of passive integrating devices with a CR39 nuclear track detector (NTD). The experimental prototype is based on the application of a new concept of NTD instrument developed at ENEA, named Alpha-PREM, acronym of piston radon exposure meter, which allows controlling the detector exposure with a patented sampling technique (Int. Eu. Pat. and US Pat.). The 'twin diffusion chambers system' was based on two A-PREM devices consisting of the standard device, named NTD-Rn, and a modified version, named NTD-Rn/Tn, which was set up to improve thoron sampling efficiency of the diffusion chamber, without changing the geometry and the start/stop function of the NTD-Rn device. Coupling devices fitted on each device allowed getting a system, which works as a double-chamber structure when deployed at the monitoring position. In this paper both technical and physical aspects are considered.

Timing and charge measurement of single gap resistive plate chamber detectors for INO-ICAL experiment

NASA Astrophysics Data System (ADS)

Gaur, Ankit; Kumar, Ashok; Naimuddin, Md.

2018-01-01

The recently approved India-based Neutrino Observatory will use the world's largest magnet to study atmospheric muon neutrinos. The 50 kiloton Iron Calorimeter consists of iron alternating with single-gap resistive plate chambers. A uniform magnetic field of ∼1.5 T is produced in the iron using toroidal-shaped copper coils. Muon neutrinos interact with the iron target to produce charged muons, which are detected by the resistive plate chambers, and tracked using orthogonal pick up strips. Timing information for each layer is used to discriminate between upward and downward traveling muons. The design of the readout electronics for the detector depends critically on an accurate model of the charge induced by the muons, and the dependence on bias voltages. In this paper, we present timing and charge response measurements using prototype detectors under different operating conditions. We also report the effect of varying gas mixture, particularly SF6, on the timing response.

Design of a New Superconducting Magnet System for High Strength Minimum-B Fields for ECRIS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Xie, D. Z.; Benitez, J. Y.; Hodgkinson, A.

A novel Mixed Axial and Radial field System (MARS) seeks to enhance the B fields inside the plasma chamber within the limits of a given conductor, thereby making it possible to raise the operating fields for Electron Cyclotron Resonance Ion Sources (ECRISs). The MARS concept consists of a hexagonally shaped closed-loop coil and a set of auxiliary solenoids. The application of MARS will be combined with a hexagonal plasma chamber to maximize the use of the radial fields at the chamber inner surfaces. Calculations using Opera's TOSCA-3D solver have shown that MARS can potentially generate up to 50% higher fieldsmore » and use of only about one half of the same superconducting wire, as compared with existing magnet designs in ECRISs. A MARS magnet system built with Nb 3 Sn coils could generate a high strength minimum-B field of maxima of ≥ 10 T on axis and ~6 T radially in an ECRIS plasma chamber. Following successful development, the MARS magnet system will be the best magnet scheme for the next generation of ECRISs. This paper will present the MARS concept, magnet design, prototyping a copper closed-loop coil, and discussions.« less

Design of a New Superconducting Magnet System for High Strength Minimum-B Fields for ECRIS

DOE PAGES

Xie, D. Z.; Benitez, J. Y.; Hodgkinson, A.; ...

2016-06-01

A novel Mixed Axial and Radial field System (MARS) seeks to enhance the B fields inside the plasma chamber within the limits of a given conductor, thereby making it possible to raise the operating fields for Electron Cyclotron Resonance Ion Sources (ECRISs). The MARS concept consists of a hexagonally shaped closed-loop coil and a set of auxiliary solenoids. The application of MARS will be combined with a hexagonal plasma chamber to maximize the use of the radial fields at the chamber inner surfaces. Calculations using Opera's TOSCA-3D solver have shown that MARS can potentially generate up to 50% higher fieldsmore » and use of only about one half of the same superconducting wire, as compared with existing magnet designs in ECRISs. A MARS magnet system built with Nb 3 Sn coils could generate a high strength minimum-B field of maxima of ≥ 10 T on axis and ~6 T radially in an ECRIS plasma chamber. Following successful development, the MARS magnet system will be the best magnet scheme for the next generation of ECRISs. This paper will present the MARS concept, magnet design, prototyping a copper closed-loop coil, and discussions.« less

PhoneSat: Ground Testing of a Phone-Based Prototype Bus

NASA Technical Reports Server (NTRS)

Felix, Carmen; Howard, Benjamin; Reyes, Matthew; Snarskiy, Fedor; Hickman, Ryan; Boshuizen, Christopher; Marshall, William

2010-01-01

Most of the key capabilities that are requisite of a satellite bus are housed in today's smart phones. PhoneSat refers to an initiative to build a ground-based prototype vehicle that could all the basic functionality of a satellite, including attitude control, using a smart Phone as its central hardware. All components used were also low cost Commercial off the Shelf (COTS). In summer 2009, an initial prototype was created using the LEGO Mindstorm toolkit demonstrating simple attitude control. Here we report on a follow up initiative to design, build and test a vehicle based on the Google s smart phone Nexus One. The report includes results from initial thermal-vacuum chamber tests and low altitude sub-orbital rocket flights which show that, at least for short durations, the Nexus One phone is able to withstand key aspects of the space environment without failure. We compare the sensor data from the Phone's accelerometers and magnetometers with that of an external microelectronic inertial measurement unit.

Thermal stress imposed by prototype bilayer and current ground crew chemical defense ensembles: a limited laboratory comparison. Final report, 30 June 1986-1 January 1987

DOE Office of Scientific and Technical Information (OSTI.GOV)

Krock, L.P.; Navalta, R.; Myhre, L.G.

An open bilayer ground-crew chemical defense ensemble (CDE) was proposed to reduce the thermal burden during vapor-only exposure periods. This study compared the thermal-stress profile of the proposed ensemble to that produced by the currently employed closed CDE. Four subjects, alternating ensembles on separate days, walked on a treadmill in an environmental chamber at 5.3 km/h (3.3 mph) and 2% grade (an energy expenditure of 350 kcal/h) for alternating work/rest to achieve significant recovery. Mean total sweat production was lower (1.38 vs. 2.50 liters) and percent sweat evaporation greater (65.7% vs. 30.0%) in the prototype ensemble than in the CDE.more » The prototype ensemble provided greater heat dissipation and allowed more-efficient sweat evaporation which had the double benefit of reducing heat storage and limiting dehydration.« less

Results from the NEXT Protogypes

DOE PAGES

Oliveira, C A.B.

2013-10-04

NEXT-100 is an electroluminescent high pressure Time Projection Chamber currently under construction. It will search for the neutrino-less double beta decay in 136Xe at the Canfranc Underground Laboratory. NEXT-100 aims to achieve nearly intrinsic energy resolution and to highly suppress background events by taking advantage of the unique properties of xenon in the gaseous phase as the detection medium. In order to prove the principle of operation and to study which are the best operational conditions, two prototypes were constructed: NEXT-DEMO and NEXT-DBDM. In this study we present the latest results from both prototypes. We report the improvement in termsmore » of light collection (~ 3x) achieved by coating the walls of NEXT-DEMO with tetraphenyl butadiene (TPB), the outstanding energy resolution of 1% (Full Width Half Maximum) from NEXT-DBDM as well as the tracking capabilities of this prototype (2.1 mm RMS error for point-like depositions) achieved by using a square array of 8 x 8 SiPMs.« less

Early Human Testing Initiative Phase 1 Regenerative Life Support Systems

NASA Image and Video Library

1995-08-08

Early Human Testing (EHT) Initiative Phase 1 Regenerative Life Support Systems Laboratory (RLSSL). Nigel Packham activities in the Variable Pressure Growth Chamber which he lived inside for 15 days. A crowd of well-wishers outside the test chamber, at the console are John Lewis, Ed Mohr and Marybeth Edeen (15577). Packham exiting the chamber (15578-81). Packham is the focus of television cameras and reporters (15582-3). Don Henninger interviewed by reporters (15584). Packham is presented with a jacket after his stay in the chamber (15585). Packham inside the wheat growth chamber checking the condition of the plants (15586-7, 15597). Packham exercising on a recumbant bicycle (15588, 15592). Packham, through the window into the growth chamber, displays a handful of wheat plants to console monitor Dan Barta (15589-90). Group portrait of the team conducting the Early Human Testing Initiative Phase 1 Regenerative Life Support Systems test and include, front row, from left: Jeff Dominick and Don Overton and back row, from left, unidentified member, Marybeth Edeen, Nigel Packham, John Lewis, Ed Mohr, Dan Barta and Tim Monk (15591). Harry Halford prepares to send a package through the airlock to Packham (15593). Packham displays a handful of wheat plants (15594). Packham fixes himself a bowl of cereal (15595) and retrieves a carton of milk from the refrigerator (15596). Packham retrieves a package from the airlock (15598). Packham packs up trash in plastic bag (15599-600) and sends it back through the airlock (15601). Packham gets a cup of water (15602) and heats it in the microwave (15603).

Web-based Tsunami Early Warning System with instant Tsunami Propagation Calculations in the GPU Cloud

NASA Astrophysics Data System (ADS)

Hammitzsch, M.; Spazier, J.; Reißland, S.

2014-12-01

Usually, tsunami early warning and mitigation systems (TWS or TEWS) are based on several software components deployed in a client-server based infrastructure. The vast majority of systems importantly include desktop-based clients with a graphical user interface (GUI) for the operators in early warning centers. However, in times of cloud computing and ubiquitous computing the use of concepts and paradigms, introduced by continuously evolving approaches in information and communications technology (ICT), have to be considered even for early warning systems (EWS). Based on the experiences and the knowledge gained in three research projects - 'German Indonesian Tsunami Early Warning System' (GITEWS), 'Distant Early Warning System' (DEWS), and 'Collaborative, Complex, and Critical Decision-Support in Evolving Crises' (TRIDEC) - new technologies are exploited to implement a cloud-based and web-based prototype to open up new prospects for EWS. This prototype, named 'TRIDEC Cloud', merges several complementary external and in-house cloud-based services into one platform for automated background computation with graphics processing units (GPU), for web-mapping of hazard specific geospatial data, and for serving relevant functionality to handle, share, and communicate threat specific information in a collaborative and distributed environment. The prototype in its current version addresses tsunami early warning and mitigation. The integration of GPU accelerated tsunami simulation computations have been an integral part of this prototype to foster early warning with on-demand tsunami predictions based on actual source parameters. However, the platform is meant for researchers around the world to make use of the cloud-based GPU computation to analyze other types of geohazards and natural hazards and react upon the computed situation picture with a web-based GUI in a web browser at remote sites. The current website is an early alpha version for demonstration purposes to give the concept a whirl and to shape science's future. Further functionality, improvements and possible profound changes have to implemented successively based on the users' evolving needs.

Multimedia Instruction in Foreign Language Classrooms: Effects on the Acquisition of the French Perfective and Imperfective Distinction

ERIC Educational Resources Information Center

Izquierdo, Jesús

2014-01-01

This study examined multimedia instruction (MI) effects on the development of the French prototypical and non-prototypical past forms among Hispanophone learners. During 4 weeks of classroom instruction, participants were exposed to MI in one of 4 conditions: learners at early stages of past-tense development received MI including prototypical (n…

Enhanced Deposition by Electrostatic Field-Assistance Aggravating Diesel Exhaust Aerosol Toxicity for Human Lung Cells.

PubMed

Stoehr, Linda C; Madl, Pierre; Boyles, Matthew S P; Zauner, Roland; Wimmer, Monika; Wiegand, Harald; Andosch, Ancuela; Kasper, Gerhard; Pesch, Markus; Lütz-Meindl, Ursula; Himly, Martin; Duschl, Albert

2015-07-21

Air pollution is associated with increased risk of cardiovascular and pulmonary diseases, but conventional air quality monitoring gives no information about biological consequences. Exposing human lung cells at the air-liquid interface (ALI) to ambient aerosol could help identify acute biological responses. This study investigated electrode-assisted deposition of diesel exhaust aerosol (DEA) on human lung epithelial cells (A549) in a prototype exposure chamber. A549 cells were exposed to DEA at the ALI and under submerged conditions in different electrostatic fields (EFs) and were assessed for cell viability, membrane integrity, and IL-8 secretion. Qualitative differences of the DEA and its deposition under different EFs were characterized using scanning mobility particle sizer (SMPS) measurements, transmission electron microscopy (TEM), and electron energy loss spectroscopy (EELS). Upon exposure to DEA only, cell viability decreased and membrane impairment increased for cells at the ALI; submerged cells were unaffected. These responses were enhanced upon application of an EF, as was DEA deposition. No adverse effects were observed for filtered DEA or air only, confirming particle-induced responses. The prototype exposure chamber proved suitable for testing DEA-induced biological responses of cells at the ALI using electrode-assisted deposition and may be useful for analysis of other air pollutants.

Performance of a resistive plate chamber equipped with a new prototype of amplified front-end electronics in the ALICE detector

NASA Astrophysics Data System (ADS)

Marchisone, Massimiliano

2017-09-01

ALICE is the LHC experiment dedicated to the study of heavy-ion collisions. At forward rapidity a muon spectrometer detects muons from low mass mesons, quarkonia (c\\bar{c} and b\\bar{b} mesons), open heavy-flavor hadrons (D and B mesons) as well as from weak bosons. A muon selection based on transverse momentum is made by a trigger system composed of 72 Resistive Plate Chambers (RPCs). For the LHC Run 1 and the ongoing Run 2 the RPCs have been equipped with a non-amplified Front-End Electronics (FEE) called ADULT. However, in view of an increase in luminosity expected for Run 3 (foreseen to start in 2021) the possibility to use an amplified FEE has been explored in order to improve the counting rate limitation and to prevent the aging of the detector by reducing the charge per hit. A prototype of this new electronics (FEERIC) has been developed and tested first with cosmic rays before equipping one RPC in the ALICE cavern with it. In this proceeding the most important performance indicators (such as efficiency, dark current, dark rate, cluster size, total charge and charge per hit) of the RPC equipped with this new FEE will be reviewed and compared to the others read out with ADULT.

Performance of a resistive plate chamber equipped with a new prototype of amplified front-end electronics

NASA Astrophysics Data System (ADS)

Marchisone, Massimiliano

2016-06-01

ALICE is the LHC experiment dedicated to the study of heavy-ion collisions. At forward rapidity a muon spectrometer detects muons from low mass mesons, quarkonia, open heavy-flavor hadrons as well as weak bosons. A muon selection based on transverse momentum is made by a trigger system composed of 72 resistive plate chambers (RPCs). For the LHC Run 1 and the ongoing Run 2 the RPCs have been equipped with a non-amplified FEE called ADULT. However, in view of an increase in luminosity expected for Run 3 (2021-2023) the possibility to use an amplified FEE has been explored in order to improve the counting rate limitation and to prevent the aging of the detector, by reducing the charge per hit. A prototype of this new electronics (FEERIC) has been developed and tested first with cosmic rays before equipping one RPC in the ALICE cavern with it. In this paper the most important performance indicators— efficiency, dark current, dark rate, cluster size and total charge —of an RPC equipped with this new FEE will be reviewed and compared to the others read out with ADULT, in pp collisions at √s=5 and 13 TeV and in Pb-Pb collisions at √sNN=5 TeV.

Performance of a large size triple GEM detector at high particle rate for the CBM Experiment at FAIR

NASA Astrophysics Data System (ADS)

Adak, Rama Prasad; Kumar, Ajit; Dubey, Anand Kumar; Chattopadhyay, Subhasis; Das, Supriya; Raha, Sibaji; Samanta, Subhasis; Saini, Jogender

2017-02-01

In CBM Experiment at FAIR, dimuons will be detected by a Muon Chamber (MUCH) consisting of segmented absorbers of varying widths and tracking chambers sandwiched between the absorber-pairs. In this fixed target heavy-ion collision experiment, operating at highest interaction rate of 10 MHz for Au+Au collision, the inner region of the 1st detector will face a particle rate of 1 MHz/cm2. To operate at such a high particle density, GEM technology based detectors have been selected for the first two stations of MUCH. We have reported earlier the performance of several small-size GEM detector prototypes built at VECC for use in MUCH. In this work, we report on a large GEM prototype tested with proton beam of momentum 2.36 GeV/c at COSY-Jülich Germany. The detector was read out using nXYTER operated in self-triggering mode. An efficiency higher than 96% at ΔVGEM = 375.2 V was achieved. The variation of efficiency with the rate of incoming protons has been found to vary within 2% when tested up to a maximum rate of 2.8 MHz/cm2. The gain was found to be stable at high particle rate with a maximum variation of ∼9%.

Dual chamber stent prevents organ malperfusion in a model of donation after cardiac death.

PubMed

Tillman, Bryan W; Chun, Youngjae; Cho, Sung Kwon; Chen, Yanfei; Liang, Nathan; Maul, Timothy; Demetris, Anthony; Gu, Xinzhu; Wagner, William R; Tevar, Amit D

2016-10-01

The paradigm for donation after cardiac death subjects donor organs to ischemic injury. A dual-chamber organ perfusion stent would maintain organ perfusion without affecting natural cardiac death. A center lumen allows uninterrupted cardiac blood flow, while an external chamber delivers oxygenated blood to the visceral vessels. A prototype organ perfusion stent was constructed from commercial stents. In a porcine model, the organ perfusion stent was deployed, followed by a simulated agonal period. Oxygenated blood perfused the external stent chamber. Organ perfusion was compared between controls (n = 3) and organ perfusion stent (n = 6). Finally, a custom, nitinol, dual chamber organ perfusion stent was fabricated using a retrievable "petal and stem" design. Endovascular organ perfusion stent deployment achieved visceral isolation without adverse impact on cardiac parameters. Visceral oxygen delivery was 4.8-fold greater compared with controls. During the agonal period, organs in organ perfusion stent-treated animals appeared well perfused in contrast with the malperfused controls. A custom nitinol and polyurethane organ perfusion stent was recaptured easily with simple sheath advancement. An organ perfusion stent maintained organ perfusion during the agonal phase in a porcine model of donation after cardiac death organ donation without adversely affecting cardiac function. Ultimately, the custom retrievable design of this study may help resolve the critical shortage of donor organs for transplant. Copyright © 2016 Elsevier Inc. All rights reserved.

Micropatterned Protective Membranes Inhibit Lens Epithelial Cell Migration in Posterior Capsule Opacification Model

PubMed Central

Magin, Chelsea M.; May, Rhea M.; Drinker, Michael C.; Cuevas, Kevin H.; Brennan, Anthony B.; Reddy, Shravanthi T.

2015-01-01

Purpose To evaluate the ability of Sharklet (SK) micropatterns to inhibit lens epithelial cell (LEC) migration. Sharklet Technologies, Inc. (STI) and InSight Innovations, LLC have proposed to develop a Sharklet-patterned protective membrane (PM) to be implanted in combination with a posterior chamber intraocular lens (IOL) to inhibit cellular migration across the posterior capsule, and thereby reduce rates of posterior capsular opacification (PCO). Methods A variety of STI micropatterns were evaluated versus smooth (SM) controls in a modified scratch wound assay for the ability to reduce or inhibit LEC migration. The best performing topography was selected, translated to a radial design, and applied to PM prototypes. The PM prototypes were tested in an in vitro PCO model for reduction of cell migration behind an IOL versus unpatterned prototypes and IOLs with no PM. In both assays, cell migration was analyzed with fluorescent microscopy. Results All SK micropatterns significantly reduced LEC migration compared with SM controls. Micropatterns that protruded from the surface reduced migration more than recessed features. The best performing micropattern reduced LEC coverage by 80%, P = 0.0001 (ANOVA, Tukey Test). Micropatterned PMs reduced LEC migration in a PCO model by 50%, P = 0.0005 (ANOVA, Tukey Test) compared with both IOLs with no PM and IOLs with SM PMs. Conclusions Collectively, in vitro results indicate the implantation of micropatterned PMs in combination with posterior chamber IOLs could significantly reduce rates of clinically relevant PCO. This innovative technology is a globally accessible solution to high PCO rates. Translational Relevance A novel IOL incorporating the SK micropattern in a membrane design surrounding the optic may help increase the success of cataract surgery by reducing secondary cataract, or PCO. PMID:25883876

A PC based fault diagnosis expert system

NASA Technical Reports Server (NTRS)

Marsh, Christopher A.

1990-01-01

The Integrated Status Assessment (ISA) prototype expert system performs system level fault diagnosis using rules and models created by the user. The ISA evolved from concepts to a stand-alone demonstration prototype using OPS5 on a LISP Machine. The LISP based prototype was rewritten in C and the C Language Integrated Production System (CLIPS) to run on a Personal Computer (PC) and a graphics workstation. The ISA prototype has been used to demonstrate fault diagnosis functions of Space Station Freedom's Operation Management System (OMS). This paper describes the development of the ISA prototype from early concepts to the current PC/workstation version used today and describes future areas of development for the prototype.

ALLTEM Multi-Axis Electromagnetic Induction System Demonstration and Validation

DTIC Science & Technology

2012-08-01

threshold T-high higher threshold TMGS Tensor Magnetic Gradiometer System TOI target of interest Tx ALLTEM transmitter USGS U.S. Geological...the Tensor Magnetic Gradiometer System ( TMGS ) and two prototype EMI instruments, the Very Early Time-domain ElectroMagnetic (VETEM) system and the...project one prototype magnetic system, the TMGS , and two prototype EMI instruments, VETEM and the High Frequency Sounder, were evaluated. Subsequent

A novel application of Fiber Bragg Grating (FBG) sensors in MPGD

NASA Astrophysics Data System (ADS)

Abbaneo, D.; Abbas, M.; Abbrescia, M.; Abi Akl, M.; Aboamer, O.; Acosta, D.; Ahmad, A.; Ahmed, W.; Aleksandrov, A.; Altieri, P.; Asawatangtrakuldee, C.; Aspell, P.; Assran, Y.; Awan, I.; Bally, S.; Ban, Y.; Banerjee, S.; Barashko, V.; Barria, P.; Bencze, G.; Beni, N.; Benussi, L.; Bhopatkar, V.; Bianco, S.; Bos, J.; Bouhali, O.; Braghieri, A.; Braibant, S.; Buontempo, S.; Calabria, C.; Caponero, M.; Caputo, C.; Cassese, F.; Castaneda, A.; Cauwenbergh, S.; Cavallo, F. R.; Celik, A.; Choi, M.; Choi, S.; Christiansen, J.; Cimmino, A.; Colafranceschi, S.; Colaleo, A.; Conde Garcia, A.; Czellar, S.; Dabrowski, M. M.; De Lentdecker, G.; De Oliveira, R.; de Robertis, G.; Dildick, S.; Dorney, B.; Endroczi, G.; Errico, F.; Fenyvesi, A.; Ferrini, M.; Ferry, S.; Furic, I.; Giacomelli, P.; Gilmore, J.; Golovtsov, V.; Guiducci, L.; Guilloux, F.; Gutierrez, A.; Hadjiiska, R. M.; Hauser, J.; Hoepfner, K.; Hohlmann, M.; Hoorani, H.; Iaydjiev, P.; Jeng, Y. G.; Kamon, T.; Karchin, P.; Korytov, A.; Krutelyov, S.; Kumar, A.; Kim, H.; Lalli, A.; Lee, J.; Lenzi, T.; Litov, L.; Loddo, F.; Madorsky, A.; Maerschalk, T.; Maggi, M.; Magnani, A.; Mal, P. K.; Mandal, K.; Marchioro, A.; Marinov, A.; Majumdar, N.; Merlin, J. A.; Mitselmakher, G.; Mohanty, A. K.; Mohapatra, A.; Molnar, J.; Muhammad, S.; Mukhopadhyay, S.; Naimuddin, M.; Nuzzo, S.; Oliveri, E.; Pant, L. M.; Paolucci, P.; Park, I.; Passamonti, L.; Passeggio, G.; Pavlov, B.; Philipps, B.; Piccolo, D.; Pierluigi, D.; Postema, H.; Primavera, F.; Puig Baranac, A.; Radi, A.; Radogna, R.; Raffone, G.; Ranieri, A.; Rashevski, G.; Riccardi, C.; Rodozov, M.; Rodrigues, A.; Ropelewski, L.; RoyChowdhury, S.; Russo, A.; Ryu, G.; Ryu, M. S.; Safonov, A.; Salva, S.; Saviano, G.; Sharma, A.; Sharma, A.; Sharma, R.; Shah, A. H.; Shopova, M.; Sturdy, J.; Sultanov, G.; Swain, S. K.; Szillasi, Z.; Talvitie, J.; Tatarinov, A.; Tuuva, T.; Tytgat, M.; Valente, M.; Vai, I.; Van Stenis, M.; Venditti, R.; Verhagen, E.; Verwilligen, P.; Vitulo, P.; Volkov, S.; Vorobyev, A.; Wang, D.; Wang, M.; Yang, U.; Yang, Y.; Yonamine, R.; Zaganidis, N.; Zenoni, F.; Zhang, A.

2018-02-01

We present a novel application of Fiber Bragg Grating (FBG) sensors in the construction and characterisation of Micro Pattern Gaseous Detector (MPGD), with particular attention to the realisation of the largest triple (Gas electron Multiplier) GEM chambers so far operated, the GE1/1 chambers of the CMS experiment at LHC. The GE1/1 CMS project consists of 144 GEM chambers of about 0.5 m2 active area each, employing three GEM foils per chamber, to be installed in the forward region of the CMS endcap during the long shutdown of LHC in 2108-2019. The large active area of each GE1/1 chamber consists of GEM foils that are mechanically stretched in order to secure their flatness and the consequent uniform performance of the GE1/1 chamber across its whole active surface. So far FBGs have been used in high energy physics mainly as high precision positioning and re-positioning sensors and as low cost, easy to mount, low space consuming temperature sensors. FBGs are also commonly used for very precise strain measurements in material studies. In this work we present a novel use of FBGs as flatness and mechanical tensioning sensors applied to the wide GEM foils of the GE1/1 chambers. A network of FBG sensors have been used to determine the optimal mechanical tension applied and to characterise the mechanical tension that should be applied to the foils. We discuss the results of the test done on a full-sized GE1/1 final prototype, the studies done to fully characterise the GEM material, how this information was used to define a standard assembly procedure and possible future developments.

Optical Sensors Based on Single Arm Thin Film Waveguide Interferometer

NASA Technical Reports Server (NTRS)

Sarkisov, Sergey S.

1997-01-01

All the goals of the research effort for the first year were met by the accomplishments. Additional efforts were done to speed up the process of development and construction of the experimental gas chamber which will be completed by the end of 1997. This chamber incorporates vacuum sealed multimode optical fiber lines which connect the sensor to the remote light source and signal processing equipment. This optical fiber line is a prototype of actual optical communication links connecting real sensors to a control unit within an aircraft or spacecraft. An important problem which we are planning to focus on during the second year is coupling of optical fiber line to the sensor. Currently this problem is solved using focusing optics and prism couplers. More reliable solutions are planned to be investigated.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wang, Xu; Shen, Fuwang; Wang, Shuai

The STAR experiment at RHIC is planning to upgrade the Time Projection Chamber which lies at the heart of the detector. We have designed an instrument to measure the tension of the wires in the multi-wire proportional chambers (MWPCs) which will be used in the TPC upgrade. The wire tension measurement system causes the wires to vibrate and then it measures the fundamental frequency of the oscillation via a laser based optical platform. The platform can scan the entire wire plane, automatically, in a single run and obtain the wire tension on each wire with high precision. In this paper,more » the details about the measurement method and the system setup will be described. In addition, the test results for a prototype MWPC to be used in the STAR-iTPC upgrade will be presented.« less

Rocket thrust chamber thermal barrier coatings

NASA Technical Reports Server (NTRS)

Quentmeyer, R. J.

1985-01-01

Subscale rocket thrust chamber tests were conducted to evaluate the effectiveness and durability of thin yttria stabilized zirconium oxide coatings applied to the thrust chamber hot-gas side wall. The fabrication consisted of arc plasma spraying the ceramic coating and bond coat onto a mandrell and then electrodepositing the copper thrust chamber wall around the coating. Chambers were fabricated with coatings .008, and .005 and .003 inches thick. The chambers were thermally cycled at a chamber pressure of 600 psia using oxygen-hydrogen as propellants and liquid hydrogen as the coolant. The thicker coatings tended to delaminate, early in the cyclic testing, down to a uniform sublayer which remained well adhered during the remaining cycles. Two chambers with .003 inch coatings were subjected to 1500 thermal cycles with no coating loss in the throat region, which represents a tenfold increase in life over identical chambers having no coatings. An analysis is presented which shows that the heat lost to the coolant due to the coating, in a rocket thrust chamber design having a coating only in the throat region, can be recovered by adding only one inch to the combustion chamber length.

Design, construction and commissioning of the Digital Hadron Calorimeter—DHCAL

NASA Astrophysics Data System (ADS)

Adams, C.; Bambaugh, A.; Bilki, B.; Butler, J.; Corriveau, F.; Cundiff, T.; Drake, G.; Francis, K.; Furst, B.; Guarino, V.; Haberichter, B.; Hazen, E.; Hoff, J.; Holm, S.; Kreps, A.; DeLurgio, P.; Matijas, Z.; Dal Monte, L.; Mucia, N.; Norbeck, E.; Northacker, D.; Onel, Y.; Pollack, B.; Repond, J.; Schlereth, J.; Skrzecz, F.; Smith, J. R.; Trojand, D.; Underwood, D.; Velasco, M.; Walendziak, J.; Wood, K.; Wu, S.; Xia, L.; Zhang, Q.; Zhao, A.

2016-07-01

A novel hadron calorimeter is being developed for future lepton colliding beam detectors. The calorimeter is optimized for the application of Particle Flow Algorithms (PFAs) to the measurement of hadronic jets and features a very finely segmented readout with 1 × 1 cm2 cells. The active media of the calorimeter are Resistive Plate Chambers (RPCs) with a digital, i.e. one-bit, readout. To first order the energy of incident particles in this calorimeter is reconstructed as being proportional to the number of pads with a signal over a given threshold. A large-scale prototype calorimeter with approximately 500,000 readout channels has been built and underwent extensive testing in the Fermilab and CERN test beams. This paper reports on the design, construction, and commissioning of this prototype calorimeter.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lee, Li -Chen; Lu, Jie; Weck, Marcus

In shell cross-linked micelles (SCMs) containing acid sites in the shell and base sites in the core are prepared from amphiphilic poly(2-oxazoline) triblock copolymers. These materials are utilized as two-chamber nanoreactors for a prototypical acid-base bifunctional tandem deacetalization-nitroaldol reaction. Furthermore, the acid and base sites are localized in different regions of the micelle, allowing the two steps in the reaction sequence to largely proceed in separate compartments, akin to the compartmentalization that occurs in biological systems.

Early Synthetic Prototyping: The Use of Video After-Action Reports for Harvesting Useful Feedback In Early Design

DTIC Science & Technology

2016-06-01

and material developers use an online game to crowdsource ideas from online players in order to increase viable synthetic prototypes. In entertainment... games , players often create videos of their game play to share with other players to demonstrate how to complete a segment of a game . This thesis...explores similar self-recorded videos of ESP game play and determines if they provide useful data to capability and material developers that can

[Changes of structures of anterior chamber angle in rabbit chronic high intraocular pressure model].

PubMed

Lei, Xun-wen; Wei, Ping; Li, Xiao-lin; Yang, Kan; Lei, Jian-zhen

2009-10-01

To observe the anterior chamber angle changes occurred in compound Carbomer-induced chronic high intraocular pressure (IOP) model in rabbit eyes. It was an experimental study. Thirty two rabbits were randomly divided into eight groups. Compound Carbomer (0.3%, 0.3 ml) was injected into the left anterior chamber. A group of rabbits were randomly killed after 1, 2, 3, 4, 6, 8, 10 and 12 weeks. The anterior chamber of the rabbit eye specimens was observed. IOP increased slowly following the application of the drug, high IOP lasted for 3 months. The drug-induced changes of anterior chamber angle consisted of early inflammatory response and late fibrous changes. Inflammatory response occurred in early stage and reduced or disappeared after 3 weeks. Fibrous degeneration and adhesion obstruction occurred in the anterior chamber angle after 4 weeks. Under the electron microscope, the trabecular was expanded and deformed, with hyperplasia of collagen and elastic fibers. Endothelial cells were separated from the trabecular, and showed the morphology of lymphocytes, with the function similar to the macrophages. Phagocytized Carbomer particles were transported through the vacuoles of Schlemm's canal endothelial cells. Large vacuoles gradually reduced. Excessive Carbomer particles were accumulated in the endothelial cells and obstructed the Schlemm's canal. This induced the fibrous proliferation and the destruction of anterior chamber angle structures. The obstruction of aqueous humor outflow induced by compound Carbomer in rabbit high IOP model is caused mainly by the changes in trabecular endothelial cells.

Suitport Feasibility - Development and Test of a Suitport and Space Suit for Human Pressurized Space Suit Donning Tests

NASA Technical Reports Server (NTRS)

Boyle, Robert M.; Mitchell, Kathryn; Allton, Charles; Ju, Hsing

2011-01-01

The suitport concept has been recently implemented as part of the small pressurized lunar rover (Currently the Space Exploration vehicle, or SEV) and the Multi-Mission Space Exploration Vehicle (MMSEV) concept demonstrator vehicle. Suitport replaces or augments the traditional airlock function of a spacecraft by providing a bulkhead opening, capture mechanism, and sealing system to allow ingress and egress of a spacesuit while the spacesuit remains outside of the pressurized volume of the spacecraft. This presents significant new opportunities to EVA exploration in both microgravity and surface environments. The suitport concept will enable three main improvements in EVA by providing reductions in: pre-EVA time from hours to less than thirty minutes; airlock consumables; contamination returned to the cabin with the EVA crewmember. To date, the first generation suitport has been tested with mockup suits on the rover cabins and pressurized on a bench top engineering unit. The work on the rover cabin has helped define the operational concepts and timelines, and has demonstrated the potential of suitport to save significant amounts of crew time before and after EVAs. The work with the engineering unit has successfully demonstrated the pressurizable seal concept including the ability to seal after the introduction and removal of contamination to the sealing surfaces. Using this experience, a second generation suitport was designed. This second generation suitport has been tested with a spacesuit prototype using the pressure differentials of the spacecraft. This test will be performed using the JSC B32 Chamber B, a human rated vacuum chamber. This test will include human rated suitports, the suitport compatible prototype suit, and chamber modifications. This test will bring these three elements together in the first ever pressurized donning of a rear entry suit through a suitport. This paper presents design of a human rated second generation suitport, modifications to the JSC human rated chamber B to accept a suitport, and a compatible space suit to support pressurized human donning of the pressurized suit through a suitport. Design challenges and solutions and compromises required to develop the system are presented. Initial human testing results are presented.

SU-F-J-147: Magnetic Field Dose Response Considerations for a Linac Monitor Chamber

DOE Office of Scientific and Technical Information (OSTI.GOV)

Reynolds, M; Fallone, B

Purpose: The impact of magnetic fields on the readings of a linac monitor chamber have not yet been investigated. Herein we examine the total dose response as well as any deviations in the beam parameters of flatness and symmetry when a Varian monitor chamber is irradiated within an applied magnetic field. This work has direct application to the development of Linac-MR systems worldwide. Methods: A Varian monitor chamber was modeled in the Monte Carlo code PENELOPE and irradiated in the presence of a magnetic field with a phase space generated from a model of a Linac-MR prototype system. The magneticmore » field strength was stepped from 0 to 3.0T in both parallel and perpendicular directions with respect to the normal surface of the phase space. Dose to each of the four regions in the monitor chamber were scored separately for every magnetic field adaptation to evaluate the effect of the magnetic field on flatness and symmetry. Results: When the magnetic field is perpendicular to the phase space normal we see a change in dose response with a maximal deviation (10–25% depending on the chamber region) near 0.75T. In the direction of electron deflection we expectedly see opposite responses in chamber regions leading to a measured asymmetry. With a magnetic field parallel to the phase space normal we see no measured asymmetries, however there is a monotonic rise in dose response leveling off at about +12% near 2.5T. Conclusion: Attention must be given to correct for the strength and direction of the magnetic field at the location of the linac monitor chamber in hybrid Linac-MR devices. Elsewise the dose sampled by these chambers may not represent the actual dose expected at isocentre; additionally there may be a need to correct for the symmetry of the beam recorded by the monitor chamber. Fallone is a co-founder and CEO of MagnetTx Oncology Solutions (under discussions to license Alberta bi-planar linac MR for commercialization).« less

Software Prototyping

PubMed Central

Del Fiol, Guilherme; Hanseler, Haley; Crouch, Barbara Insley; Cummins, Mollie R.

2016-01-01

Summary Background Health information exchange (HIE) between Poison Control Centers (PCCs) and Emergency Departments (EDs) could improve care of poisoned patients. However, PCC information systems are not designed to facilitate HIE with EDs; therefore, we are developing specialized software to support HIE within the normal workflow of the PCC using user-centered design and rapid prototyping. Objective To describe the design of an HIE dashboard and the refinement of user requirements through rapid prototyping. Methods Using previously elicited user requirements, we designed low-fidelity sketches of designs on paper with iterative refinement. Next, we designed an interactive high-fidelity prototype and conducted scenario-based usability tests with end users. Users were asked to think aloud while accomplishing tasks related to a case vignette. After testing, the users provided feedback and evaluated the prototype using the System Usability Scale (SUS). Results Survey results from three users provided useful feedback that was then incorporated into the design. After achieving a stable design, we used the prototype itself as the specification for development of the actual software. Benefits of prototyping included having 1) subject-matter experts heavily involved with the design; 2) flexibility to make rapid changes, 3) the ability to minimize software development efforts early in the design stage; 4) rapid finalization of requirements; 5) early visualization of designs; 6) and a powerful vehicle for communication of the design to the programmers. Challenges included 1) time and effort to develop the prototypes and case scenarios; 2) no simulation of system performance; 3) not having all proposed functionality available in the final product; and 4) missing needed data elements in the PCC information system. PMID:27081404

Performance of timing resistive plate chambers with relativistic neutrons from 300 to 1500 MeV

NASA Astrophysics Data System (ADS)

Blanco, A.; Adamczewski-Musch, J.; Boretzky, K.; Cabanelas, P.; Cartegni, L.; Ferreira Marques, R.; Fonte, P.; Fruehauf, J.; Galaviz, D.; Heil, M.; Henriques, A.; Ickert, G.; Körper, D.; Lopes, L.; Palka, M.; Pereira, A.; Rossi, D.; Simon, H.; Teubig, P.; Traxler, M.; Velho, P.; Altstadt, S.; Atar, L.; Aumann, T.; Bemmerer, D.; Caesar, C.; Charpy, A.; Elekes, Z.; Fiori, E.; Gasparic, I.; Gerbig, J.; Göbel, K.; Heftrich, T.; Heine, M.; Heinz, A.; Holl, M.; Ignatov, A.; Isaak, J.; Johansson, H.; Kelic-Heil, A.; Lederer, C.; Lindberg, S.; Löher, B.; Machado, J.; Marganiec, J.; Martensson, M.; Nilsson, T.; Panin, V.; Paschalis, S.; Petri, M.; Plag, R.; Pohl, M.; Rastrepina, G.; Reifarth, R.; Reinhardt, T. P.; Röder, M.; Savran, D.; Scheit, H.; Schrock, P.; Silva, J.; Stach, D.; Strannerdahl, F.; Thies, R.; Wagner, A.; Wamers, F.; Weigand, M.

2015-02-01

A prototype composed of four resistive plate chamber layers has been exposed to quasi-monoenergetic neutrons produced from a deuteron beam of varying energy (300 to 1500 AMeV) in experiment S406 at GSI, Darmstad, Germany. Each layer, with an active area of about 2000 × 500 mm2, is made of modules containing the active gaps, all in multigap construction. Each gap is defined by 0.3 mm nylon mono-filaments positioned between 2.85 mm thick float glass electrodes. The modules are operated in avalanche mode with a non-flammable gas mixture composed of 90% C2H2F4 and 10% SF6. The signals are readout by a pick-up electrode formed by 15 copper strips (per layer), spaced at a pitch of 30 mm, connected at both sides to timing front end electronics. Measurements of the time of flight jitter of neutrons, in the mentioned energy range, point to a contribution of the resistive plate chamber in the order of 150 ps, independent of the neutron energy.

Studies of beam plasma interactions in a space simulation chamber using prototype Space Shuttle instruments

NASA Technical Reports Server (NTRS)

Banks, P. M.; Raitt, W. J.; Denig, W. F.

1982-01-01

In March, 1981, electron beam experiments were conducted in a large space simulation chamber using equipment destined to be flown aboard NASA's Office of Space Science-1 pallet (OSS-1). Two major flight experiments were involved. They include the Vehicle Charging and Potential (VCAP) experiment and the Plasma Diagnostics Package (PDP). Apparatus connected with VCAP included a Fast Pulse Electron Gun (FPEG), and a Charge and Current Probe (CCP). A preliminary view is provided of the results obtained when the electron emissions were held steady over relatively long periods of time such that steady state conditions could be obtained with respect to the electron beam interaction with the neutral gases and plasma of the vacuum chamber. Of particular interest was the plasma instability feature known as the Beam Plasma Discharge. For the present experiments the FPEG was used in a dc mode with a range of currents of 2 to 80 mA at a beam energy of 970 eV. Attention is given to the emissions of VLF and HF noise associated with the dc beam.

Fusion technologies for Laser Inertial Fusion Energy (LIFE)

NASA Astrophysics Data System (ADS)

Kramer, K. J.; Latkowski, J. F.; Abbott, R. P.; Anklam, T. P.; Dunne, A. M.; El-Dasher, B. S.; Flowers, D. L.; Fluss, M. J.; Lafuente, A.; Loosmore, G. A.; Morris, K. R.; Moses, E.; Reyes, S.

2013-11-01

The Laser Inertial Fusion-based Energy (LIFE) engine design builds upon on going progress at the National Ignition Facility (NIF) and offers a near-term pathway to commercial fusion. Fusion technologies that are critical to success are reflected in the design of the first wall, blanket and tritium separation subsystems. The present work describes the LIFE engine-related components and technologies. LIFE utilizes a thermally robust indirect-drive target and a chamber fill gas. Coolant selection and a large chamber solid-angle coverage provide ample tritium breeding margin and high blanket gain. Target material selection eliminates the need for aggressive chamber clearing, while enabling recycling. Demonstrated tritium separation and storage technologies limit the site tritium inventory to attractive levels. These key technologies, along with the maintenance and advanced materials qualification program have been integrated into the LIFE delivery plan. This describes the development of components and subsystems, through prototyping and integration into a First Of A Kind power plant. This work performed under the auspices of the U.S. Department of Energy by Lawrence Livermore National Laboratory under Contract DE-AC52-07NA27344.

Integrated aeroelastic vibrator for fluid mixing in open microwells

NASA Astrophysics Data System (ADS)

Xia, H. M.; Jin, X.; Zhang, Y. Y.; Wu, J. W.; Zhang, J.; Wang, Z. P.

2018-01-01

Fluid mixing in micro-wells/chambers is required in a variety of biological and biochemical processes. However, mixing fluids of small volumes is usually difficult due to increased viscous effects. In this study, we propose a new method for mixing enhancement in microliter-scale open wells. A thin elastic diaphragm is used to seal the bottom of the mixing microwell, underneath which an air chamber connects an aeroelastic vibrator. Driven by an air flow, the vibrator produces self-excited vibrations and causes pressure oscillations in the air chamber. Then the elastic diaphragm is actuated to mix the fluids in the microwell. Two designs that respectively have one single well and 2  ×  2 wells were prototyped. Testing results show that for liquids with a volume ranging from 10-60 µl and viscosity ranging from 1-5 cP, complete mixing can be obtained within 5-20 s. Furthermore, the device is operable with an air micropump, and hence facilitating the miniaturization and integration of lab-on-a-chip and microbioreactor systems.

Technology Development of a Fiber Optic-Coupled Laser Ignition System for Multi-Combustor Rocket Engines

NASA Technical Reports Server (NTRS)

Trinh, Huu P.; Early, Jim; Osborne, Robin; Thomas, Matthew E.; Bossard, John A.

2002-01-01

This paper addresses the progress of technology development of a laser ignition system at NASA Marshall Space Flight Center (MSFC). The first two years of the project focus on comprehensive assessments and evaluations of a novel dual-pulse laser concept, flight- qualified laser system, and the technology required to integrate the laser ignition system to a rocket chamber. With collaborations of the Department of Energy/Los Alamos National Laboratory (LANL) and CFD Research Corporation (CFDRC), MSFC has conducted 26 hot fire ignition tests with lab-scale laser systems. These tests demonstrate the concept feasibility of dual-pulse laser ignition to initiate gaseous oxygen (GOX)/liquid kerosene (RP-1) combustion in a rocket chamber. Presently, a fiber optic- coupled miniaturized laser ignition prototype is being implemented at the rocket chamber test rig for future testing. Future work is guided by a technology road map that outlines the work required for maturing a laser ignition system. This road map defines activities for the next six years, with the goal of developing a flight-ready laser ignition system.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Biewer, Theodore M.; Marcus, Chris; Klepper, C Christopher

The divertor-specific ITER Diagnostic Residual Gas Analyzer (DRGA) will provide essential information relating to DT fusion plasma performance. This includes pulse-resolving measurements of the fuel isotopic mix reaching the pumping ducts, as well as the concentration of the helium generated as the ash of the fusion reaction. In the present baseline design, the cluster of sensors attached to this diagnostic's differentially pumped analysis chamber assembly includes a radiation compatible version of a commercial quadrupole mass spectrometer, as well as an optical gas analyzer using a plasma-based light excitation source. This paper reports on a laboratory study intended to validate themore » performance of this sensor cluster, with emphasis on the detection limit of the isotopic measurement. This validation study was carried out in a laboratory set-up that closely prototyped the analysis chamber assembly configuration of the baseline design. This includes an ITER-specific placement of the optical gas measurement downstream from the first turbine of the chamber's turbo-molecular pump to provide sufficient light emission while preserving the gas dynamics conditions that allow for \\textasciitilde 1 s response time from the sensor cluster [1].« less

Prototype Development and Evaluation of Self-Cleaning Concentrated Solar Power Collectors

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mazumder, Malay K.; Horenstein, Mark N.; Joglekar, Nitin R.

The feasibility of integrating and retrofitting transparent electrodynamic screens (EDS) on the front surfaces of solar collectors was established as a means to provide active self-cleaning properties for parabolic trough and heliostat reflectors, solar panels, and Fresnel lenses. Prototype EDS-integrated solar collectors, including second-surface glass mirrors, metallized Acrylic-film mirrors, and dielectric mirrors, were produced and tested in environmental test chambers for removing the dust layer deposited on the front surface of the mirrors. The evaluation of the prototype EDS-integrated mirrors was conducted using dust and environmental conditions that simulate the field conditions of the Mojave Desert. Test results showed thatmore » the specular reflectivity of the mirrors could be maintained at over 90% over a wide range of dust loadings ranging from 0 to 10 g/m 2, with particle diameter varying from 1 to 50 μm. The measurement of specular reflectivity (SR) was performed using a D&S Reflectometer at wavelength 660 nm. A non-contact reflectometer was designed and constructed for rapid measurement of specular reflectivity at the same wavelength. The use of this new noncontact instrument allowed us to measure SR before and after EDS activation. Several EDS prototypes were constructed and evaluated with different electrode configurations, electrode materials, and encapsulating dielectric materials.« less

Prototype Combined Heater/Thermoelectric Power Generator for Remote Applications

NASA Astrophysics Data System (ADS)

Champier, D.; Favarel, C.; Bédécarrats, J. P.; Kousksou, T.; Rozis, J. F.

2013-07-01

This study presents a prototype thermoelectric generator (TEG) developed for remote applications in villages that are not connected to the electrical power grid. For ecological and economic reasons, there is growing interest in harvesting waste heat from biomass stoves to produce some electricity. Because regular maintenance is not required, TEGs are an attractive choice for small-scale power generation in inaccessible areas. The prototype developed in our laboratory is especially designed to be implemented in stoves that are also used for domestic hot water heating. The aim of this system is to provide a few watts to householders, so they have the ability to charge cellular phones and radios, and to get some light at night. A complete prototype TEG using commercial (bismuth telluride) thermoelectric modules has been built, including system integration with an electric DC/DC converter. The DC/DC converter has a maximum power point tracker (MPPT) driven by an MC9SO8 microcontroller, which optimizes the electrical energy stored in a valve-regulated lead-acid battery. Physical models were used to study the behavior of the thermoelectric system and to optimize the performance of the MPPT. Experiments using a hot gas generator to simulate the exhaust of the combustion chamber of a stove are used to evaluate the system. Additionally, potential uses of such generators are presented.

Developing IEC prototypes for adolescents. IEC workshop.

PubMed

1997-01-01

Participants of the IEC Workshop for the Production of OHP Material on Reproductive Health for Adolescents and Young Adults held November 25-30 in Japan developed innovative, visually appealing overhead projector (OHP) transparencies to serve as prototype information, education, and communication (IEC) materials for the Asian Region. The materials cover a wide range of topics from early marriage to unwanted pregnancy. This paper briefly describes the prototypes. One group focused upon early marriage, an issue of considerable importance to the health and welfare of young women in countries such as Bhutan, India, and Nepal. Participants from China, Laos, Malaysia, and Thailand focused upon the issue of gender equality, while a third group developed OHP material to teach a range of issues related to young people's sexual and reproductive health. Finally, the fourth group, drawn from Indonesia, the Philippines, and Vietnam, focused upon the topic of menstruation with a prototype targeted to boys and girls aged 9-14 years. Boys were included to foster their understanding of menstruation as a natural phenomenon.

A novel system for organ and tissues preservation: the refrigerating hyperbaric chamber.

PubMed

Guimarães, F A G; Taha, M O; Simões, M J; Moino, C A A; Santos, I V; Amador, J C; Santos, R A; Queiroz, R B; Amaro, R R; Jesus, M A S

2006-01-01

This study was designed to investigate the feasibility of building a simple and inexpensive device to preserve organs or tissues in hyperbaric and hypothermic conditions. The device was built on a 40-cm wide, 28-cm long, and 23-cm deep stainless steel chassis. The pressure vessel was built by a 7.8-cm bore stainless steel cylinder put inside another 12-cm cylinder welded together and closed by a steel plate on the top and bottom. The inferior plate was welded, and the superior one was fixed by manual clasp nut. The cooling system is made up of air compressor, condenser, expansion area, and cooling worm that is located between the cylinders. The temperature-controlling device is a computer processor contained in an integrated-circuit chip, with a on-off system to maintain the chamber temperature between 2 degrees to 4 degrees C. The compression of the chamber is performed by lateral coupling with the oxygen cylinder and is maintained at 5.5 absolute atmospheres and controlled by air pressure gauge. The maximal work pressure was evaluated by spreadsheet. Temperature or pressure changes were evaluated by 12- and 24-hour assays. The maximal work pressure permitted was 6.5 absolute atmospheres. Thus, the container was free from danger. The temperature inside the chamber was kept between 2 degrees and 4 degrees C. The production costs of the prototype was US$1000. The manufacture of the refrigerating hyperbaric chamber is viable, simple, and inexpensive.

Cosmic Ray Inspection and Passive Tomography for SNM Detection

DOE Office of Scientific and Technical Information (OSTI.GOV)

Armitage, John; Oakham, Gerald; Bryman, Douglas

2009-12-02

The Cosmic Ray Inspection and Passive Tomography (CRIPT) project has recently started investigating the detection of illicit Special Nuclear Material in cargo using cosmic ray muon tomography and complementary neutron detectors. We are currently performing simulation studies to help with the design of small scale prototypes. Based on the prototype tests and refined simulations, we will determine whether the muon tracking system for the full scale prototype will be based on drift chambers or extruded scintillator trackers. An analysis of the operations of the Port of Montreal has determined how long muon scan times should take if all or amore » subset of the cargo is to be screened. As long as the throughput of the muon system(s) is equal to the rate at which containers are unloaded from ships, the impact on port operations would not be great if a muon scanning stage were required for all cargo. We also show preliminary simulation results indicating that excellent separation between Al, Fe and Pb is possible under ideal conditions. The discrimination power is reduced but still significant when realistic momentum resolution measurements are considered.« less

Cosmic Ray Inspection and Passive Tomography for SNM Detection

NASA Astrophysics Data System (ADS)

Armitage, John; Bryman, Douglas; Cousins, Thomas; Gallant, Grant; Jason, Andrew; Jonkmans, Guy; Noël, Scott; Oakham, Gerald; Stocki, Trevor J.; Waller, David

2009-12-01

The Cosmic Ray Inspection and Passive Tomography (CRIPT) project has recently started investigating the detection of illicit Special Nuclear Material in cargo using cosmic ray muon tomography and complementary neutron detectors. We are currently performing simulation studies to help with the design of small scale prototypes. Based on the prototype tests and refined simulations, we will determine whether the muon tracking system for the full scale prototype will be based on drift chambers or extruded scintillator trackers. An analysis of the operations of the Port of Montreal has determined how long muon scan times should take if all or a subset of the cargo is to be screened. As long as the throughput of the muon system(s) is equal to the rate at which containers are unloaded from ships, the impact on port operations would not be great if a muon scanning stage were required for all cargo. We also show preliminary simulation results indicating that excellent separation between Al, Fe and Pb is possible under ideal conditions. The discrimination power is reduced but still significant when realistic momentum resolution measurements are considered.

Design Considerations for Gun Propellant Climatic Storage Chambers.

DTIC Science & Technology

1982-11-01

Schematic diagram of thermal element 5 4. Prototype Lhermal element 6 5. Power control circuit diagram 7 6. Power control module 7 7. Temperature...plates. Each plate is powered through a triac and temperature control circuit as shown in figure 5. Figure 6 is a photograph of an assembled power control...SHEATER PLATES Figure 5. Power control circuit diagram 4 f Figure 6. Power control module WSR.L-0295-TR -8- Figure 7. Temperature control module 9 -WSRL

Development of a Pulsed Combustion Actuator For High-Speed Flow Control

NASA Technical Reports Server (NTRS)

Cutler, Andrew D.; Beck, B. Terry; Wilkes, Jennifer A.; Drummond, J. Philip; Alderfer, David W.; Danehy, Paul M.

2005-01-01

This paper describes the flow within a prototype actuator, energized by pulsed combustion or detonations, that provides a pulsed jet suitable for flow control in high-speed applications. A high-speed valve, capable of delivering a pulsed stream of reactants a mixture of H2 and air at rates of up to 1500 pulses per second, has been constructed. The reactants burn in a resonant chamber, and the products exit the device as a pulsed jet. High frequency pressure transducers have been used to monitor the pressure fluctuations in the device at various reactant injection frequencies, including both resonant and off-resonant conditions. The combustion chamber has been constructed with windows, and the flow inside it has been visualized using Planar Laser-Induced Fluorescence (PLIF). The pulsed jet at the exit of the device has been observed using schlieren.

Space shuttle orbital maneuvering engine platelet injector program

NASA Technical Reports Server (NTRS)

1975-01-01

A platelet-face injector for the fully reusable orbit maneuvering system OMS on the space shuttle was evaluated as a means of obtaining additional design margin and low cost. Performance, heat transfer, and combustion stability were evaluated over the anticipated range of OMS operating conditions. The effects of acoustic cavity configuration on combustion stability, including cavity depth, open area, inlet contour, and other parameters, were investigated using sea level bomb tests. Prototype injector and chamber behavior was evaluated for a variety of conditions; these tests examined the effects of film cooling, helium saturated propellants, chamber length, inlet conditions, and operating point, on performance, heat transfer and engine transient behavior. Helium bubble ingestion into both propellant circuits was investigated, as was chugging at low pressure operation, and hot and cold engine restart with and without a purge.

Gas mixture studies for streamer operated Resistive Plate Chambers

NASA Astrophysics Data System (ADS)

Paoloni, A.; Longhin, A.; Mengucci, A.; Pupilli, F.; Ventura, M.

2016-06-01

Resistive Plate Chambers operated in streamer mode are interesting detectors in neutrino and astro-particle physics applications (like OPERA and ARGO experiments). Such experiments are typically characterized by large area apparatuses with no stringent requirements on detector aging and rate capabilities. In this paper, results of cosmic ray tests performed on a RPC prototype using different gas mixtures are presented, the principal aim being the optimization of the TetraFluoroPropene concentration in Argon-based mixtures. The introduction of TetraFluoroPropene, besides its low Global Warming Power, is helpful because it simplifies safety requirements allowing to remove also isobutane from the mixture. Results obtained with mixtures containing SF6, CF4, CO2, N2 and He are also shown, presented both in terms of detectors properties (efficiency, multiple-streamer probability and time resolution) and in terms of streamer characteristics.

A Compact and Low Cost Electronic Nose for Aroma Detection

PubMed Central

Macías, Miguel Macías; Agudo, J. Enrique; Manso, Antonio García; Orellana, Carlos Javier García; Velasco, Horacio Manuel González; Caballero, Ramón Gallardo

2013-01-01

This article explains the development of a prototype of a portable and a very low-cost electronic nose based on an mbed microcontroller. Mbeds are a series of ARM microcontroller development boards designed for fast, flexible and rapid prototyping. The electronic nose is comprised of an mbed, an LCD display, two small pumps, two electro-valves and a sensor chamber with four TGS Figaro gas sensors. The performance of the electronic nose has been tested by measuring the ethanol content of wine synthetic matrices and special attention has been paid to the reproducibility and repeatability of the measurements taken on different days. Results show that the electronic nose with a neural network classifier is able to discriminate wine samples with 10, 12 and 14% V/V alcohol content with a classification error of less than 1%. PMID:23698265

A small Unix-based data acquisition system

DOE Office of Scientific and Technical Information (OSTI.GOV)

Engberg, D.; Glanzman, T.

1994-02-01

The proposed SLAC B Factory detector plans to use Unix-based machines for all aspects of computing, including real-time data acquisition and experimental control. A R and D program has been established to investigate the use of Unix in the various aspects of experimental computation. Earlier R and D work investigated the basic real-time aspects of the IBM RS/6000 workstation running AIX, which claims to be a real-time operating system. The next step in this R and D is the construction of a prototype data acquisition system which attempts to exercise many of the features needed in the final on-line systemmore » in a realistic situation. For this project, the authors have combined efforts with a team studying the use of novel cell designs and gas mixtures in a new prototype drift chamber.« less

National Ignition Facility Project: An Update

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hogan, W J; Moses, E; Warner, B

2000-12-07

The National Ignition Facility (NIF) consists of 192 forty-centimeter-square laser beams and a 10-m-diameter target chamber. Physical construction began in 1997. The Laser and Target Area Building and the Optics Assembly Building were the first major construction activities, and despite several unforeseen obstacles, the buildings are now 92% complete and have been done on time and within cost. Prototype component development and testing has proceeded in parallel. Optics vendors have installed full-scale production lines and have done prototype production runs. The assembly and integration of the beampath infrastructure has been reconsidered and a new approach has been developed. This papermore » will discuss the status of the NIF project and the plans for completion. It will also include summary information on Laser MegaJoule (LMJ) provided by M. Andre, LMJ Project Director.« less

The National Ignition Facility Project: An Update

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hogan, W.J.; Moses, E.; Warner, B.

2000-12-07

The National Ignition Facility (NIT) consists of 192 forty-centimeter-square laser beams and a 10-m-diameter target chamber. Physical construction began in 1997. The Laser and Target Area Building and the Optics Assembly Building were the first major construction activities, and despite several unforeseen obstacles, the buildings are now 92% complete and have been done on time and within cost. Prototype component development and testing has proceeded in parallel. Optics vendors have installed full-scale production lines and have done prototype production runs. The assembly and integration of the beam path infrastructure has been reconsidered and a new approach has been developed. Thismore » paper will discuss the status of the NIF project and the plans for completion. It will also include summary information on Laser MegaJoule (LMJ) provided by M. Andre, LMJ Project Director.« less

Development of a liquid xenon time projection chamber for the XENON dark matter search

NASA Astrophysics Data System (ADS)

Ni, Kaixuan

This thesis describes the research conducted for the XENON dark matter direct detection experiment. The tiny energy and small cross-section, from the interaction of dark matter particle on the target, requires a low threshold and sufficient background rejection capability of the detector. The XENON experiment uses dual phase technology to detect scintillation and ionization simultaneously from an event in liquid xenon (LXe). The distinct ratio, between scintillation and ionization, for nuclear recoil and electron recoil events provides excellent background rejection potential. The XENON detector is designed to have 3D position sensitivity down to mm scale, which provides additional event information for background rejection. Started in 2002, the XENON project made steady progress in the R&D phase during the past few years. Those include developing sensitive photon detectors in LXe, improving the energy resolution and LXe purity for detecting very low energy events. Two major quantities related to the dark matter detection, the scintillation efficiency and ionization yield of nuclear recoils in LXe, have been established. A prototype dual phase detector (XENON3) has been built and tested extensively in above ground laboratory. The 3D position sensitivity, as well as the background discrimination potential demonstrated from the XENON3 prototype, allows the construction of a 10 kg scale detector (XENON10), to be deployed underground in early 2006. With 99.5% electron recoil rejection efficiency and 16 keVr nuclear recoil energy threshold, XENON10 will be able to probe the WIMP-nucleon cross-section down to 2 x 10-44 cm2 in the supersymmetry parameter space, after one month operation in the Gran Sasso underground laboratory.

Sintering of Lunar and Simulant Glass

NASA Technical Reports Server (NTRS)

Cooper, Bonnie L.

2007-01-01

Most oxygen-extraction techniques are temperature-dependent, with higher temperatures resulting in higher oxygen yield. An example is hydrogen reduction, in which the optimum process temperature is 1050 C. However, glass-rich lunar soil begins to show the effects of sintering at temperatures of 900 C or lower. Sintering welds particles together due to viscous relaxation of the glass in the sample. One approach to avoid problems related to sintering, such as difficulty in removing waste material from the reactor, is to keep the soil in motion. One of several methods being studied to accomplish this is fluidized-bed processing techniques, in which the grains are kept in motion by the action of flowing reductant gas. The spent material can be removed from the chamber while still fluidized, or the fluidizing motion can continue until the material has cooled below approx. 500 C. Until end-to-end prototypes are built that can remove the heated soil, the most practical option is to keep the bed fluidized while cooling the waste material. As ISRU technology advances, another option will become valuable, which is to intentionally sinter the material to a great enough extent that it becomes a brick. The free iron in lunar soil is magnetic, and ferromagnetic bricks can be manipulated by robotic systems using electromagnetic end effectors. Finally, if an electromagnetic field is applied to the soil while the brick is being formed, the brick itself will become a magnet. This property can be used to create self-aligning bricks or other building materials that do not require fasteners. Although sintering creates a challenge for early lunar surface systems, knowledge gained during prototype development will be valuable for the advanced lunar outpost.

Software Prototyping: A Case Report of Refining User Requirements for a Health Information Exchange Dashboard.

PubMed

Nelson, Scott D; Del Fiol, Guilherme; Hanseler, Haley; Crouch, Barbara Insley; Cummins, Mollie R

2016-01-01

Health information exchange (HIE) between Poison Control Centers (PCCs) and Emergency Departments (EDs) could improve care of poisoned patients. However, PCC information systems are not designed to facilitate HIE with EDs; therefore, we are developing specialized software to support HIE within the normal workflow of the PCC using user-centered design and rapid prototyping. To describe the design of an HIE dashboard and the refinement of user requirements through rapid prototyping. Using previously elicited user requirements, we designed low-fidelity sketches of designs on paper with iterative refinement. Next, we designed an interactive high-fidelity prototype and conducted scenario-based usability tests with end users. Users were asked to think aloud while accomplishing tasks related to a case vignette. After testing, the users provided feedback and evaluated the prototype using the System Usability Scale (SUS). Survey results from three users provided useful feedback that was then incorporated into the design. After achieving a stable design, we used the prototype itself as the specification for development of the actual software. Benefits of prototyping included having 1) subject-matter experts heavily involved with the design; 2) flexibility to make rapid changes, 3) the ability to minimize software development efforts early in the design stage; 4) rapid finalization of requirements; 5) early visualization of designs; 6) and a powerful vehicle for communication of the design to the programmers. Challenges included 1) time and effort to develop the prototypes and case scenarios; 2) no simulation of system performance; 3) not having all proposed functionality available in the final product; and 4) missing needed data elements in the PCC information system.

EPDM Based Double Slope Triangular Enclosure Solar Collector: A Novel Approach

PubMed Central

Qureshi, Shafiq R.; Khan, Waqar A.

2014-01-01

Solar heating is one of the important utilities of solar energy both in domestic and industrial sectors. Evacuated tube heaters are a commonly used technology for domestic water heating. However, increasing cost of copper and nickel has resulted in huge initial cost for these types of heaters. Utilizing solar energy more economically for domestic use requires new concept which has low initial and operating costs together with ease of maintainability. As domestic heating requires only nominal heating temperature to the range of 60–90°C, therefore replacing nickel coated copper pipes with any cheap alternate can drastically reduce the cost of solar heater. We have proposed a new concept which utilizes double slope triangular chamber with EPDM based synthetic rubber pipes. This has reduced the initial and operating costs substantially. A detailed analytical study was carried out to design a novel solar heater. On the basis of analytical design, a prototype was manufactured. Results obtained from the experiments were found to be in good agreement with the analytical study. A maximum error of 10% was recorded at noon. However, results show that error is less than 5% in early and late hours. PMID:24688407

EPDM based double slope triangular enclosure solar collector: a novel approach.

PubMed

Qureshi, Shafiq R; Khan, Waqar A; Sarwar, Waqas

2014-01-01

Solar heating is one of the important utilities of solar energy both in domestic and industrial sectors. Evacuated tube heaters are a commonly used technology for domestic water heating. However, increasing cost of copper and nickel has resulted in huge initial cost for these types of heaters. Utilizing solar energy more economically for domestic use requires new concept which has low initial and operating costs together with ease of maintainability. As domestic heating requires only nominal heating temperature to the range of 60-90 °C, therefore replacing nickel coated copper pipes with any cheap alternate can drastically reduce the cost of solar heater. We have proposed a new concept which utilizes double slope triangular chamber with EPDM based synthetic rubber pipes. This has reduced the initial and operating costs substantially. A detailed analytical study was carried out to design a novel solar heater. On the basis of analytical design, a prototype was manufactured. Results obtained from the experiments were found to be in good agreement with the analytical study. A maximum error of 10% was recorded at noon. However, results show that error is less than 5% in early and late hours.

Acid–base bifunctional shell cross-linked micelle nanoreactor for one-pot tandem reaction

DOE PAGES

Lee, Li -Chen; Lu, Jie; Weck, Marcus; ...

2015-12-29

In shell cross-linked micelles (SCMs) containing acid sites in the shell and base sites in the core are prepared from amphiphilic poly(2-oxazoline) triblock copolymers. These materials are utilized as two-chamber nanoreactors for a prototypical acid-base bifunctional tandem deacetalization-nitroaldol reaction. Furthermore, the acid and base sites are localized in different regions of the micelle, allowing the two steps in the reaction sequence to largely proceed in separate compartments, akin to the compartmentalization that occurs in biological systems.

Advanced Plant Habitat

NASA Image and Video Library

2016-11-17

A test unit, or prototype, of NASA's Advanced Plant Habitat (APH) was delivered to the Space Station Processing Facility at the agency's Kennedy Space Center in Florida. The APH is the largest plant chamber built for the agency. The unit is being prepared for engineering development tests to see how the science will integrate with the various systems of the plant habitat. It will have 180 sensors and four times the light output of Veggie. The APH will be delivered to the International Space Station in March 2017.

Advanced Plant Habitat

NASA Image and Video Library

2016-11-17

A test unit, or prototype, of NASA's Advanced Plant Habitat (APH) was delivered to the Space Station Processing Facility at the agency's Kennedy Space Center in Florida. The APH is the largest plant chamber built for the agency. The base of the APH is being prepared for engineering development tests to see how the science will integrate with the various systems of the plant habitat. It will have 180 sensors and four times the light output of Veggie. The APH will be delivered to the International Space Station in March 2017.

WE-F-16A-02: Design, Fabrication, and Validation of a 3D-Printed Proton Filter for Range Spreading

DOE Office of Scientific and Technical Information (OSTI.GOV)

Remmes, N; Courneyea, L; Corner, S

2014-06-15

Purpose: To design, fabricate and test a 3D-printed filter for proton range spreading in scanned proton beams. The narrow Bragg peak in lower-energy synchrotron-based scanned proton beams can result in longer treatment times for shallow targets due to energy switching time and plan quality degradation due to minimum monitor unit limitations. A filter with variable thicknesses patterned on the same scale as the beam's lateral spot size will widen the Bragg peak. Methods: The filter consists of pyramids dimensioned to have a Gaussian distribution in thickness. The pyramids are 2.5mm wide at the base, 0.6 mm wide at the peak,more » 5mm tall, and are repeated in a 2.5mm pseudo-hexagonal lattice. Monte Carlo simulations of the filter in a proton beam were run using TOPAS to assess the change in depth profiles and lateral beam profiles. The prototypes were constrained to a 2.5cm diameter disk to allow for micro-CT imaging of promising prototypes. Three different 3D printers were tested. Depth-doses with and without the prototype filter were then measured in a ~70MeV proton beam using a multilayer ion chamber. Results: The simulation results were consistent with design expectations. Prototypes printed on one printer were clearly unacceptable on visual inspection. Prototypes on a second printer looked acceptable, but the micro-CT image showed unacceptable voids within the pyramids. Prototypes from the third printer appeared acceptable visually and on micro-CT imaging. Depth dose scans using the prototype from the third printer were consistent with simulation results. Bragg peak width increased by about 3x. Conclusions: A prototype 3D printer pyramid filter for range spreading was successfully designed, fabricated and tested. The filter has greater design flexibility and lower prototyping and production costs compared to traditional ridge filters. Printer and material selection played a large role in the successful development of the filter.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Averyanov, A. V.; Bajajin, A. G.; Chepurnov, V. F.

The time-projection chamber (TPC) is the main tracking detector in the MPD/NICA. The information on charge-particle tracks in the TPC is registered by the MWPG with cathode pad readout. The frontend electronics (FEE) are developed with use of modern technologies such as application specific integrated circuits (ASIC), field-programmable gate arrays (FPGA), and data transfer to a concentrator via a fast optical interface. The main parameters of the FEE are as follows: total number of channels, ∼95 000; data stream from the whole TPC, 5 GB/s; low power consumption, less than 100 mW/ch; signal to noise ratio (S/N), 30; equivalent noisemore » charge (ENC), <1000e{sup –} (C{sub in} = 10–20 pF); and zero suppression (pad signal rejection ∼90%). The article presents the status of the readout chamber construction and the data acquisition system. The results of testing FEE prototypes are presented.« less

Ionization imaging—A new method to search for 0- ν ββ decay

NASA Astrophysics Data System (ADS)

Chinowski, W.; Goldschmidt, A.; Nygren, D.; Bernstein, A.; Heffner, M.; Millaud, J.

2007-10-01

We present a new method to search for 0- ν ββ decay in 136Xe, the Ionization Imaging Chamber. This concept is based on 3-D track reconstruction by detection of ionization, without avalanche gain, in a novel time projection chamber (TPC) geometry. The rejection efficiency of external charged particle backgrounds is optimized by the realization of a maximal, fully active, closed, and ex post facto variable fiducial surface. Event localization within the fiducial volume and detailed event reconstruction mitigate external neutral particle backgrounds; larger detectors offer higher rejection efficiencies. Energy resolution at the Q-value of 2.5 MeV is expected to be better than 1% FWHM, reducing the potential impact of allowed 2- ν ββ decays. Scaling from ˜25 kg prototype to 1000+ kg target mass is graceful. A new possible methodology for the identification of the daughter barium nucleus is also described.

Demonstrator Detection System for the Active Target and Time Projection Chamber (ACTAR TPC) project

NASA Astrophysics Data System (ADS)

Roger, T.; Pancin, J.; Grinyer, G. F.; Mauss, B.; Laffoley, A. T.; Rosier, P.; Alvarez-Pol, H.; Babo, M.; Blank, B.; Caamaño, M.; Ceruti, S.; Daemen, J.; Damoy, S.; Duclos, B.; Fernández-Domínguez, B.; Flavigny, F.; Giovinazzo, J.; Goigoux, T.; Henares, J. L.; Konczykowski, P.; Marchi, T.; Lebertre, G.; Lecesne, N.; Legeard, L.; Maugeais, C.; Minier, G.; Osmond, B.; Pedroza, J. L.; Pibernat, J.; Poleshchuk, O.; Pollacco, E. C.; Raabe, R.; Raine, B.; Renzi, F.; Saillant, F.; Sénécal, P.; Sizun, P.; Suzuki, D.; Swartz, J. A.; Wouters, C.; Wittwer, G.; Yang, J. C.

2018-07-01

The design, realization and operation of a prototype or "demonstrator" version of an active target and time projection chamber (ACTAR TPC) for experiments in nuclear physics is presented in detail. The heart of the detection system features a MICROMEGAS gas amplifier coupled to a high-density pixelated pad plane with square pad sizes of 2 × 2 mm2. The detector has been thoroughly tested with several different gas mixtures over a wide range of pressures and using a variety of sources of ionizing radiation including laser light, an α-particle source and heavy-ion beams of 24Mg and 58Ni accelerated to energies of 4.0 MeV/u. Results from these tests and characterization of the detector response over a wide range of operating conditions will be described. These developments have served as the basis for the design of a larger detection system that is presently under construction.

An instrument employing electronic counters and an emulsion chamber for studying heavy cosmic ray interactions (JACEE-3)

NASA Technical Reports Server (NTRS)

Austin, R. W.; Meegan, C. A.; Parnell, T. A.; Selig, W. J.; Watts, J. W.; Burnett, T. H.; Iwai, J.; Lord, J. J.; Strauscz, S.; Wilkes, R. J.;

Secondary gamma-ray production in a coded aperture mask

NASA Technical Reports Server (NTRS)

Owens, A.; Frye, G. M., Jr.; Hall, C. J.; Jenkins, T. L.; Pendleton, G. N.; Carter, J. N.; Ramsden, D.; Agrinier, B.; Bonfand, E.; Gouiffes, C.

1985-01-01

The application of the coded aperture mask to high energy gamma-ray astronomy will provide the capability of locating a cosmic gamma-ray point source with a precision of a few arc-minutes above 20 MeV. Recent tests using a mask in conjunction with drift chamber detectors have shown that the expected point spread function is achieved over an acceptance cone of 25 deg. A telescope employing this technique differs from a conventional telescope only in that the presence of the mask modifies the radiation field in the vicinity of the detection plane. In addition to reducing the primary photon flux incident on the detector by absorption in the mask elements, the mask will also be a secondary radiator of gamma-rays. The various background components in a CAMTRAC (Coded Aperture Mask Track Chamber) telescope are considered. Monte-Carlo calculations are compared with recent measurements obtained using a prototype instrument in a tagged photon beam line.

Design and implementation of wire tension measurement system for MWPCs used in the STAR iTPC upgrade

DOE PAGES

Wang, Xu; Shen, Fuwang; Wang, Shuai; ...

2017-04-06

The STAR experiment at RHIC is planning to upgrade the Time Projection Chamber which lies at the heart of the detector. We have designed an instrument to measure the tension of the wires in the multi-wire proportional chambers (MWPCs) which will be used in the TPC upgrade. The wire tension measurement system causes the wires to vibrate and then it measures the fundamental frequency of the oscillation via a laser based optical platform. The platform can scan the entire wire plane, automatically, in a single run and obtain the wire tension on each wire with high precision. In this paper,more » the details about the measurement method and the system setup will be described. In addition, the test results for a prototype MWPC to be used in the STAR-iTPC upgrade will be presented.« less

Design and implementation of wire tension measurement system for MWPCs used in the STAR iTPC upgrade

NASA Astrophysics Data System (ADS)

Wang, Xu; Shen, Fuwang; Wang, Shuai; Feng, Cunfeng; Li, Changyu; Lu, Peng; Thomas, Jim; Xu, Qinghua; Zhu, Chengguang

2017-07-01

The STAR experiment at RHIC is planning to upgrade the Time Projection Chamber which lies at the heart of the detector. We have designed an instrument to measure the tension of the wires in the multi-wire proportional chambers (MWPCs) which will be used in the TPC upgrade. The wire tension measurement system causes the wires to vibrate and then it measures the fundamental frequency of the oscillation via a laser based optical platform. The platform can scan the entire wire plane, automatically, in a single run and obtain the wire tension on each wire with high precision. In this paper, the details about the measurement method and the system setup will be described. In addition, the test results for a prototype MWPC to be used in the STAR-iTPC upgrade will be presented.

Study of a micro chamber quadrupole mass spectrometer

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wang Jinchan; Zhang Xiaobing; Mao Fuming

The design of a micro chamber quadrupole mass spectrometer (MCQMS) having a small total volume of only 20 cm{sup 3}, including Faraday cup ion detector and ion source, is described. This MCQMS can resist a vacuum baking temperature of 400-500 deg. C. The quadrupole elements with a hyperbolic surface are made of a ceramic material and coated with a thin metal layer. The quadrupole mass filter has a field radius of 3 mm and a length of 100 mm. Prototypes of this new MCQMS can detect a minimum partial pressure of 10{sup -8} Pa, have a peak width of {delta}M=1more » at 10% peak height from mass number 1 to 60, and show an excellent long-term stability. The new MCQMS is intended to be used in residual gas analyses of electron devices during a mutual pumping and baking process.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Thuillier, T.; Lamy, T.; Latrasse, L.

A-PHOENIX is a new compact hybrid electron cyclotron resonance ion source using a large permanent magnet hexapole (1.92 T at the magnet surface) and high temperature superconducting Solenoids (3 T) to make min-vertical bar B vertical bar structure suitable for 28 GHz cw operation. The final assembly of the source was achieved at the end of June 2007. The first plasma of A-PHOENIX at 18 GHz was done on the 16th of August, 2007. The technological specificities of A-PHOENIX are presented. The large hexapole built is presented and experimental magnetic measurements show that it is nominal with respect to simulation.more » A fake plasma chamber prototype including thin iron inserts showed that the predicted radial magnetic confinement can be fulfilled up to 2.15 T at the plasma chamber wall. Scheduled planning of experiments until the end of 2008 is presented.« less

Imaging open-path Fourier transform infrared spectrometer for 3D cloud profiling

NASA Astrophysics Data System (ADS)

Rentz Dupuis, Julia; Mansur, David J.; Vaillancourt, Robert; Carlson, David; Evans, Thomas; Schundler, Elizabeth; Todd, Lori; Mottus, Kathleen

2010-04-01

OPTRA has developed an imaging open-path Fourier transform infrared (I-OP-FTIR) spectrometer for 3D profiling of chemical and biological agent simulant plumes released into test ranges and chambers. An array of I-OP-FTIR instruments positioned around the perimeter of the test site, in concert with advanced spectroscopic algorithms, enables real time tomographic reconstruction of the plume. The approach is intended as a referee measurement for test ranges and chambers. This Small Business Technology Transfer (STTR) effort combines the instrumentation and spectroscopic capabilities of OPTRA, Inc. with the computed tomographic expertise of the University of North Carolina, Chapel Hill. In this paper, we summarize the design and build and detail system characterization and test of a prototype I-OP-FTIR instrument. System characterization includes radiometric performance and spectral resolution. Results from a series of tomographic reconstructions of sulfur hexafluoride plumes in a laboratory setting are also presented.

Design, fabrication and delivery of a prototype saturator for ACPL

NASA Technical Reports Server (NTRS)

Keyser, G.; Rogers, C. F.; Squires, P.

1979-01-01

The design configuration and performance characteristics of a saturator developed to provide ground-based simulation for some of the experiments for ACPL-1 first flights of Spacelab are described, some difficulties encountered with the apparatus are discussed, and recommendations concerning testing of this type of instrument are presented. The saturators provide a means of accurately fixing the water vapor mixing ratio of an aerosol sample. Dew point temperatures from almost freezing to ambient room temperatures can be attained with high precision. The instruments can accommodate aerosol flow rates approaching 1000 cc/s. Provisions were made to inject aerosols upstream of these saturators, although downstream injection can be accomplished as well. A device of this type will be used in the ACPL-1 to condition various aerosols delivered concurrently to a CFD, expansion chamber, and static diffusion chamber used in zero gravity cloud-forming experiments. The saturator was designed to meet the requirements projected for the flight instrument.

Navigation lock for Bonneville Dam, Columbia River, Oregon. Volume II. Appendix A. Pressures during lock operations. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Stockstill, R.L.; George, J.F.

1996-09-01

Tests were conducted on two different 1:25-scale models of the New Bonneville Lock located on the Columbia River in Oregon. The lock models were built to study the filling and emptying systems, which consisted of designs utilizing bottom longitudinal floor culverts. The first design studied, defined as the H-H pattern system, consisted of four longitudinal flood culverts in each end of the lock chamber. The second system studied had two longitudinal floor culverts in each end of the lock chamber and was defined as the H pattern system. In the H-H pattern system, the filling culverts, which were located undermore » the lock chamber floor, connected to a crossover culvert with a horizontal splitter wall dividing the flow to upstream and downstream splitter manifolds were equal divisions led into four longitudinal flood culverts in each end of the lock chamber. With the type 6 (recommended) design and a 1-min valve opening time, the lock chamber filled in 8.7 min and emptied in 12.1 min. Due to differences in friction losses, the prototype can be expected to fill and empty about 20 percent faster than the model (7.0 min and 9.7 min, respectively). Modifications involving installing a slope in the lower sill and a v-notch design in the high sill were significant factors that resulted in fast filling and emptying times, low hawser forces, and only minor movement with various tow arrangements for different operating scenarios.« less

Applying Early Systems Engineering: Injecting Knowledge into the Capability Development Process

DTIC Science & Technology

2012-10-01

involves early use of systems engi- neering and technical analyses to supplement the existing operational analysis techniques currently used in...complexity, and costs of systems now being developed require tight coupling between operational requirements stated in the CDD, system requirements...Fleischer » Keywords: Capability Development, Competitive Prototyping, Knowledge Points, Early Systems Engineering Applying Early Systems

Apparatus and Method for Low-Temperature Training of Shape Memory Alloys

NASA Technical Reports Server (NTRS)

Swanger, A. M.; Fesmire, J. E.; Trigwell, S.; Gibson, T. L.; Williams, M. K.; Benafan, O.

2015-01-01

An apparatus and method for the low-temperature thermo-mechanical training of shape memory alloys (SMA) has been developed. The experimental SMA materials are being evaluated as prototypes for applicability in novel thermal management systems for future cryogenic applications. Alloys providing two-way actuation at cryogenic temperatures are the chief target. The mechanical training regimen was focused on the controlled movement of rectangular strips, with S-bend configurations, at temperatures as low as 30 K. The custom holding fixture included temperature sensors and a low heat-leak linear actuator with a magnetic coupling. The fixture was mounted to a Gifford-McMahon cryocooler providing up to 25 W of cooling power at 20 K and housed within a custom vacuum chamber. Operations included both training cycles and verification of shape memory movement. The system design and operation are discussed. Results of the training for select prototype alloys are presented.

An RF-only ion-funnel for extraction from high-pressure gases

DOE PAGES

Brunner, T.; Fudenberg, D.; Varentsov, V.; ...

2015-01-27

An RF ion-funnel technique has been developed to extract ions from a high-pressure (10 bar) noble-gas environment into a vacuum (10 -6 mbar). Detailed simulations have been performed and a prototype has been developed for the purpose of extracting 136Ba ions from Xe gas with high efficiency. With this prototype, ions have been extracted for the first time from high-pressure xenon gas and argon gas. Systematic studies have been carried out and compared to simulations. This demonstration of extraction of ions, with mass comparable to that of the gas generating the high-pressure, has applications to Ba tagging from a Xe-gasmore » time-projection chamber for double-beta decay, as well as to the general problem of recovering trace amounts of an ionized element in a heavy (m > 40 u) carrier gas.« less

Z-2 Prototype Space Suit Development

NASA Technical Reports Server (NTRS)

Ross, Amy; Rhodes, Richard; Graziosi, David; Jones, Bobby; Lee, Ryan; Haque, Bazle Z.; Gillespie, John W., Jr.

2014-01-01

NASA's Z-2 prototype space suit is the highest fidelity pressure garment from both hardware and systems design perspectives since the Shuttle Extravehicular Mobility Unit (EMU) was developed in the late 1970's. Upon completion it will be tested in the 11' humanrated vacuum chamber and the Neutral Buoyancy Laboratory (NBL) at the NASA Johnson Space Center to assess the design and to determine applicability of the configuration to micro-, low- (asteroid), and planetary- (surface) gravity missions. This paper discusses the 'firsts' the Z-2 represents. For example, the Z-2 sizes to the smallest suit scye bearing plane distance for at least the last 25 years and is being designed with the most intensive use of human models with the suit model. The paper also provides a discussion of significant Z-2 configuration features, and how these components evolved from proposal concepts to final designs.

Z-2 Prototype Space Suit Development

NASA Technical Reports Server (NTRS)

Ross, Amy; Rhodes, Richard; Graziosi, David

2014-01-01

NASA's Z-2 prototype space suit is the highest fidelity pressure garment from both hardware and systems design perspectives since the Shuttle Extravehicular Mobility Unit (EMU) was developed in the late 1970's. Upon completion it will be tested in the 11' human-rated vacuum chamber and the Neutral Buoyancy Laboratory (NBL) at the NASA Johnson Space Center to assess the design and to determine applicability of the configuration to micro-, low- (asteroid), and planetary- (surface) gravity missions. This paper discusses the 'firsts' the Z-2 represents. For example, the Z-2 sizes to the smallest suit scye bearing plane distance for at least the last 25 years and is being designed with the most intensive use of human models with the suit model. The paper also provides a discussion of significant Z-2 configuration features, and how these components evolved from proposal concepts to final designs.

Semi-autonomous inline water analyzer: design of a common light detector for bacterial, phage, and immunological biosensors.

PubMed

Descamps, Elodie C T; Meunier, Damien; Brutesco, Catherine; Prévéral, Sandra; Franche, Nathalie; Bazin, Ingrid; Miclot, Bertrand; Larosa, Philippe; Escoffier, Camille; Fantino, Jean-Raphael; Garcia, Daniel; Ansaldi, Mireille; Rodrigue, Agnès; Pignol, David; Cholat, Pierre; Ginet, Nicolas

2017-01-01

The use of biosensors as sensitive and rapid alert systems is a promising perspective to monitor accidental or intentional environmental pollution, but their implementation in the field is limited by the lack of adapted inline water monitoring devices. We describe here the design and initial qualification of an analyzer prototype able to accommodate three types of biosensors based on entirely different methodologies (immunological, whole-cell, and bacteriophage biosensors), but whose responses rely on the emission of light. We developed a custom light detector and a reaction chamber compatible with the specificities of the three systems and resulting in statutory detection limits. The water analyzer prototype resulting from the COMBITOX project can be situated at level 4 on the Technology Readiness Level (TRL) scale and this technical advance paves the way to the use of biosensors on-site.

Apparatus and method for low-temperature training of shape memory alloys

NASA Astrophysics Data System (ADS)

Swanger, A. M.; Fesmire, J. E.; Trigwell, S.; Gibson, T. L.; Williams, M. K.; Benafan, O.

2015-12-01

An apparatus and method for the low-temperature thermo-mechanical training of shape memory alloys (SMA) has been developed. The experimental SMA materials are being evaluated as prototypes for applicability in novel thermal management systems for future cryogenic applications. Alloys providing two-way actuation at cryogenic temperatures are the chief target. The mechanical training regimen was focused on the controlled movement of rectangular strips, with S-bend configurations, at temperatures as low as 30 K. The custom holding fixture included temperature sensors and a low heat-leak linear actuator with a magnetic coupling. The fixture was mounted to a Gifford-McMahon cryocooler providing up to 25 W of cooling power at 20 K and housed within a custom vacuum chamber. Operations included both training cycles and verification of shape memory movement. The system design and operation are discussed. Results of the training for select prototype alloys are presented.

Realization of an omnidirectional source of sound using parametric loudspeakers.

PubMed

Sayin, Umut; Artís, Pere; Guasch, Oriol

2013-09-01

Parametric loudspeakers are often used in beam forming applications where a high directivity is required. Withal, in this paper it is proposed to use such devices to build an omnidirectional source of sound. An initial prototype, the omnidirectional parametric loudspeaker (OPL), consisting of a sphere with hundreds of ultrasonic transducers placed on it has been constructed. The OPL emits audible sound thanks to the parametric acoustic array phenomenon, and the close proximity and the large number of transducers results in the generation of a highly omnidirectional sound field. Comparisons with conventional dodecahedron loudspeakers have been made in terms of directivity, frequency response, and in applications such as the generation of diffuse acoustic fields in reverberant chambers. The OPL prototype has performed better than the conventional loudspeaker especially for frequencies higher than 500 Hz, its main drawback being the difficulty to generate intense pressure levels at low frequencies.

Anterior chamber paracentesis to improve diagnosis and treatment of infectious uveitis in South Africa.

PubMed

Schaftenaar, Erik; Lecuona, Karin; Baarsma, Seerp; Meenken, Christina; Verjans, Georges; McIntyre, James; Peters, Remco

2015-09-22

Infectious uveitis is a significant cause of blindness in South Africa, especially among HIV-infected individuals. The visual outcome of uveitis depends on early clinical and laboratory diagnosis to guide therapeutic intervention. Analyses of aqueous humor, obtained by anterior chamber paracentesis, directs the differential diagnosis in infectious uveitis. However, although safe and potentially cost-effective, diagnostic anterior chamber paracentesis is not common practice in ophthalmic care across Africa. We seek to draw attention to this important procedure that could improve the diagnosis and prognosis of infectious uveitis.

Earthquake early Warning ShakeAlert system: West coast wide production prototype

USGS Publications Warehouse

Kohler, Monica D.; Cochran, Elizabeth S.; Given, Douglas; Guiwits, Stephen; Neuhauser, Doug; Hensen, Ivan; Hartog, Renate; Bodin, Paul; Kress, Victor; Thompson, Stephen; Felizardo, Claude; Brody, Jeff; Bhadha, Rayo; Schwarz, Stan

2017-01-01

Earthquake early warning (EEW) is an application of seismological science that can give people, as well as mechanical and electrical systems, up to tens of seconds to take protective actions before peak earthquake shaking arrives at a location. Since 2006, the U.S. Geological Survey has been working in collaboration with several partners to develop EEW for the United States. The goal is to create and operate an EEW system, called ShakeAlert, for the highest risk areas of the United States, starting with the West Coast states of California, Oregon, and Washington. In early 2016, the Production Prototype v.1.0 was established for California; then, in early 2017, v.1.2 was established for the West Coast, with earthquake notifications being distributed to a group of beta users in California, Oregon, and Washington. The new ShakeAlert Production Prototype was an outgrowth from an earlier demonstration EEW system that began sending test notifications to selected users in California in January 2012. ShakeAlert leverages the considerable physical, technical, and organizational earthquake monitoring infrastructure of the Advanced National Seismic System, a nationwide federation of cooperating seismic networks. When fully implemented, the ShakeAlert system may reduce damage and injury caused by large earthquakes, improve the nation’s resilience, and speed recovery.

Laboratory-based validation of the baseline sensors of the ITER diagnostic residual gas analyzer

NASA Astrophysics Data System (ADS)

Klepper, C. C.; Biewer, T. M.; Marcus, C.; Andrew, P.; Gardner, W. L.; Graves, V. B.; Hughes, S.

2017-10-01

The divertor-specific ITER Diagnostic Residual Gas Analyzer (DRGA) will provide essential information relating to DT fusion plasma performance. This includes pulse-resolving measurements of the fuel isotopic mix reaching the pumping ducts, as well as the concentration of the helium generated as the ash of the fusion reaction. In the present baseline design, the cluster of sensors attached to this diagnostic's differentially pumped analysis chamber assembly includes a radiation compatible version of a commercial quadrupole mass spectrometer, as well as an optical gas analyzer using a plasma-based light excitation source. This paper reports on a laboratory study intended to validate the performance of this sensor cluster, with emphasis on the detection limit of the isotopic measurement. This validation study was carried out in a laboratory set-up that closely prototyped the analysis chamber assembly configuration of the baseline design. This includes an ITER-specific placement of the optical gas measurement downstream from the first turbine of the chamber's turbo-molecular pump to provide sufficient light emission while preserving the gas dynamics conditions that allow for \\textasciitilde 1 s response time from the sensor cluster [1].

Radiation effects on active camera electronics in the target chamber at the National Ignition Facility

NASA Astrophysics Data System (ADS)

Dayton, M.; Datte, P.; Carpenter, A.; Eckart, M.; Manuel, A.; Khater, H.; Hargrove, D.; Bell, P.

2017-08-01

The National Ignition Facility's (NIF) harsh radiation environment can cause electronics to malfunction during high-yield DT shots. Until now there has been little experience fielding electronic-based cameras in the target chamber under these conditions; hence, the performance of electronic components in NIF's radiation environment was unknown. It is possible to purchase radiation tolerant devices, however, they are usually qualified for radiation environments different to NIF, such as space flight or nuclear reactors. This paper presents the results from a series of online experiments that used two different prototype camera systems built from non-radiation hardened components and one commercially available camera that permanently failed at relatively low total integrated dose. The custom design built in Livermore endured a 5 × 1015 neutron shot without upset, while the other custom design upset at 2 × 1014 neutrons. These results agreed with offline testing done with a flash x-ray source and a 14 MeV neutron source, which suggested a methodology for developing and qualifying electronic systems for NIF. Further work will likely lead to the use of embedded electronic systems in the target chamber during high-yield shots.

In Vitro Capture of Small Ferrous Particles with a Magnetic Filtration Device Designed for Intravascular Use with Intraarterial Chemotherapy: Proof-of-Concept Study.

PubMed

Mabray, Marc C; Lillaney, Prasheel; Sze, Chia-Hung; Losey, Aaron D; Yang, Jeffrey; Kondapavulur, Sravani; Liu, Derek; Saeed, Maythem; Patel, Anand; Cooke, Daniel; Jun, Young-Wook; El-Sayed, Ivan; Wilson, Mark; Hetts, Steven W

2016-03-01

To establish that a magnetic device designed for intravascular use can bind small iron particles in physiologic flow models. Uncoated iron oxide particles 50-100 nm and 1-5 µm in size were tested in a water flow chamber over a period of 10 minutes without a magnet (ie, control) and with large and small prototype magnets. These same particles and 1-µm carboxylic acid-coated iron oxide beads were likewise tested in a serum flow chamber model without a magnet (ie, control) and with the small prototype magnet. Particles were successfully captured from solution. Particle concentrations in solution decreased in all experiments (P < .05 vs matched control runs). At 10 minutes, concentrations were 98% (50-100-nm particles in water with a large magnet), 97% (50-100-nm particles in water with a small magnet), 99% (1-5-µm particles in water with a large magnet), 99% (1-5-µm particles in water with a small magnet), 95% (50-100-nm particles in serum with a small magnet), 92% (1-5-µm particles in serum with a small magnet), and 75% (1-µm coated beads in serum with a small magnet) lower compared with matched control runs. This study demonstrates the concept of magnetic capture of small iron oxide particles in physiologic flow models by using a small wire-mounted magnetic filter designed for intravascular use. Copyright © 2016 SIR. Published by Elsevier Inc. All rights reserved.

Relative effect of temperature and pH on diel cycling of dissolved trace elements in prickly pear creek, Montana

USGS Publications Warehouse

Jones, Clain A.; Nimick, D.A.; McCleskey, R. Blaine

2004-01-01

Diel (24 hr) cycles in dissolved metal and As concentrations have been documented in many northern Rocky Mountain streams in the U.S.A. The cause(s) of the cycles are unknown, although temperature- and pH-dependent sorption reactions have been cited as likely causes. A light/dark experiment was conducted to isolate temperature and pH as variables affecting diel metal cycles in Prickly Pear Creek, Montana. Light and dark chambers containing sediment and a strand of macrophyte were placed in the stream to simulate instream temperature oscillations. Photosynthesis-induced pH changes were allowed to proceed in the light chambers while photosynthesis was prevented in the dark chambers. Water samples were collected periodically for 22 hr in late July 2001 from all chambers and the stream. In the stream, dissolved Zn concentrations increased by 300% from late afternoon to early morning, while dissolved As concentrations exhibited the opposite pattern, increasing 33% between early morning and late afternoon. Zn and As concentrations in the light chambers showed similar, though less pronounced, diel variations. Conversely, Zn and As concentrations in the dark chambers had no obvious diel variation, indicating that light, or light-induced reactions, caused the variation. Temperature oscillations were nearly identical between light and dark chambers, strongly suggesting that temperature was not controlling the diel variations. As expected, pH was negatively correlated (P < 0.01) with dissolved Zn concentrations and positively correlated with dissolved As concentrations in both the light and dark chambers. From these experiments, photosynthesis-induced pH changes were determined to be the major cause of the diel dissolved Zn and As cycles in Prickly Pear Creek. Further research is necessary in other streams to verify that this finding is consistent among streams having large differences in trace-element concentrations and mineralogy of channel substrate. ?? 2004 Kluwer Academic Publishers.

Clinical trials of the prototype Rutherford Appleton Laboratory MWPC positron camera at the Royal Marsden Hospital

NASA Astrophysics Data System (ADS)

Flower, M. A.; Ott, R. J.; Webb, S.; Leach, M. O.; Marsden, P. K.; Clack, R.; Khan, O.; Batty, V.; McCready, V. R.; Bateman, J. E.

1988-06-01

Two clinical trials of the prototype RAL multiwire proportional chamber (MWPC) positron camera were carried out prior to the development of a clinical system with large-area detectors. During the first clinical trial, the patient studies included skeletal imaging using 18F, imaging of brain glucose metabolism using 18F FDG, bone marrow imaging using 52Fe citrate and thyroid imaging with Na 124I. Longitudinal tomograms were produced from the limited-angle data acquisition from the static detectors. During the second clinical trial, transaxial, coronal and sagittal images were produced from the multiview data acquisition. A more detailed thyroid study was performed in which the volume of the functioning thyroid tissue was obtained from the 3D PET image and this volume was used in estimating the radiation dose achieved during radioiodine therapy of patients with thyrotoxicosis. Despite the small field of view of the prototype camera, and the use of smaller than usual amounts of activity administered, the PET images were in most cases comparable with, and in a few cases visually better than, the equivalent planar view using a state-of-the-art gamma camera with a large field of view and routine radiopharmaceuticals.

Bioregenerative system components for microgravity

NASA Technical Reports Server (NTRS)

Nevill, Gale E., Jr.; Hessel, Michael I., Jr.

1992-01-01

The goal of the class was to design, fabricate, and test prototype designs that were independent, yet applicable to a Closed Loop Life Support System. The three prototypes chosen were in the areas of agar plant growth, regnerative filtration, and microgravity food preparation. The plant growth group designed a prototype agar medium growth system that incorporates nutrient solution replenishment and post-harvest refurbishment. In addition, the unit emphasizes material containment and minimization of open interfaces. The second project was a filter used in microgravity that has the capability to clean itself. The filters are perforated plates which slide through a duct and are cleaned outside of the flow with a vacuum system. The air in the duct is prevented from flowing outside of the duct by a network of sliding seals. The food preparation group developed a device which dispenses and mixes ingredients and then cooks the mixture in microgravity. The dry ingredients are dispensed from a canister by a ratchet-operated piston. The wet ingredients are dispensed from plastic bags through tubing attached to a syringe. Once inside the mixing chamber, the ingredients are mixed using a collapsible whisk and then pushed into the cooking device.

System development and early biological tests in NASA's biomass production chamber

NASA Technical Reports Server (NTRS)

Wheeler, R. M.; Mackowiak, C. L.; Dreschel, T. W.; Sager, J. C.; Prince, R. P.; Knott, W. M.; Hinkle, C. R.; Strayer, R. F.

1990-01-01

The Biomass Production Chamber at Kennedy Space Center was constructed to conduct large scale plant growth studies for NASA's CELSS program. Over the past four years, physical systems and computer control software have been continually upgraded and the degree of atmospheric leakage from the chamber has decreased from about 40 to 5 percent of the total volume per day. Early tests conducted with a limited degree of closure showed that total crop (wheat) growth from the best trays was within 80 percent of reported optimal yields for similar light levels. Yields from subsequent tests under more tightly closed conditions have not been as good--up to only 65 percent of optimal yields. Yields appear to have decreased with increasing closure, yet potential problems exist in cultural techniques and further studies are warranted. With the ability to tightly seal the chamber, quantitative data were gathered on CO2 and water exchange rates. Results showed that stand photosynthesis and transpiration reached a peak near 25 days after planting, soon after full vegetative ground cover was established. In the final phase of testing when atmospheric closure was the highest, ethylene gas levels in the chamber rose from about 10 to nearly 120 ppb. Evidence suggests that the ethylene originated from the wheat plants themselves and may have caused an epinastic rolling of the leaves, but no apparent detrimental effects on whole plant function.

Suitport Feasibility: Development and Test of a Suitport and Space Suit for Human Pressurized Space Suit Donning Tests

NASA Technical Reports Server (NTRS)

Boyle, Robert M.; Mitchell, Kathryn; Allton, Charles; Ju, Hsing

2012-01-01

The suitport concept has been recently implemented as part of the small pressurized lunar rover (Currently the Space Exploration vehicle, or SEV) and the Multi-Mission Space Exploration Vehicle (MMSEV) concept demonstrator vehicle. Suitport replaces or augments the traditional airlock function of a spacecraft by providing a bulkhead opening, capture mechanism, and sealing system to allow ingress and egress of a space suit while the space suit remains outside of the pressurized volume of the spacecraft. This presents significant new opportunities to EVA exploration in both microgravity and surface environments. The suitport concept will enable three main improvements in EVA by providing reductions in: pre-EVA time from hours to less than thirty minutes; airlock consumables; contamination returned to the cabin with the EVA crewmember. To date, the first generation suitport has been tested with mockup suits on the rover cabins and pressurized on a bench top engineering unit. The work on the rover cabin has helped define the operational concepts and timelines, and has demonstrated the potential of suitport to save significant amounts of crew time before and after EVAs. The work with the engineering unit has successfully demonstrated the pressurizable seal concept including the ability to seal after the introduction and removal of contamination to the sealing surfaces. Using this experience, a second generation suitport was designed. This second generation suitport has been tested with a space suit prototype on the second generation MMSEV cabin, and testing is planned using the pressure differentials of the spacecraft. Pressurized testing will be performed using the JSC B32 Chamber B, a human rated vacuum chamber. This test will include human rated suitports, a suitport compatible prototype suit, and chamber modifications. This test will bring these three elements together in the first ever pressurized donning of a rear entry suit through a suitport. This paper presents the design of a human rated second generation suitport, the design of a suit capable of supporting pressurized human donning through a suitport, ambient pressure testing of the suit with the suitport, and modifications to the JSC human rated chamber B to accept a suitport. Design challenges and solutions, as well as compromises required to develop the system, are presented. Initial human testing results are presented.

Evaluation and Characterization Study of Dual Pulse Laser-Induced Spark (DPLIS) for Rocket Engine Ignition System Application

NASA Technical Reports Server (NTRS)

Osborne, Robin; Wehrmeyer, Joseph; Trinh, Huu; Early, James

2003-01-01

This paper addresses the progress of technology development of a laser ignition system at NASA Marshall Space Flight Center (MSFC). Laser ignition has been used at MSFC in recent test series to successfully ignite RP1/GOX propellants in a subscale rocket chamber, and other past studies by NASA GRC have demonstrated the use of laser ignition for rocket engines. Despite the progress made in the study of this ignition method, the logistics of depositing laser sparks inside a rocket chamber have prohibited its use. However, recent advances in laser designs, the use of fiber optics, and studies of multi-pulse laser formats3 have renewed the interest of rocket designers in this state-of the-art technology which offers the potential elimination of torch igniter systems and their associated mechanical parts, as well as toxic hypergolic ignition systems. In support of this interest to develop an alternative ignition system that meets the risk-reduction demands of Next Generation Launch Technology (NGLT), characterization studies of a dual pulse laser format for laser-induced spark ignition are underway at MSFC. Results obtained at MSFC indicate that a dual pulse format can produce plasmas that absorb the laser energy as efficiently as a single pulse format, yet provide a longer plasma lifetime. In an experiments with lean H2/air propellants, the dual pulse laser format, containing the same total energy of a single laser pulse, produced a spark that was superior in its ability to provide sustained ignition of fuel-lean H2/air propellants. The results from these experiments are being used to optimize a dual pulse laser format for future subscale rocket chamber tests. Besides the ignition enhancement, the dual pulse technique provides a practical way to distribute and deliver laser light to the combustion chamber, an important consideration given the limitation of peak power that can be delivered through optical fibers. With this knowledge, scientists and engineers at Los Alamos National Laboratory and CFD Research Corporation have designed and fabricated a miniaturized, first-generation optical prototype of a laser ignition system that could be the basis for a laser ignition system for rocket applications. This prototype will be tested at MSFC in future subscale rocket ignition tests.

Operational test of the prototype peewee yarder.

Treesearch

Charles N. Mann; Ronald W. Mifflin

1979-01-01

An operational test of a small, prototype running skyline yarder was conducted early in 1978. Test results indicate that this yarder concept promises a low cost, high performance system for harvesting small logs where skyline methods are indicated. Timber harvest by thinning took place on 12 uphill and 2 downhill skyline roads, and clearcut harvesting was performed on...

Power Teaching Prototype: New Paradigm Education at Edward Waters College. Occasional Paper #7

ERIC Educational Resources Information Center

Fluellen, Jerry Ellsworth, Jr.

2009-01-01

Since, its early development in our nation's capital, the Power Teaching Prototype (PTP) has evolved to connect three factors likely to characterize 21st Century teaching and learning. Teaching for understanding requires a clear method of designing instruction and a simple, yet powerful, way of delivering. For the design of instruction, Harvard…

Studies of Implicit Prototype Extraction in Patients with Mild Cognitive Impairment and Early Alzheimer's Disease

ERIC Educational Resources Information Center

Nosofsky, Robert M.; Denton, Stephen E.; Zaki, Safa R.; Murphy-Knudsen, Anne F.; Unverzagt, Frederick W.

2012-01-01

Studies of incidental category learning support the hypothesis of an implicit prototype-extraction system that is distinct from explicit memory (Smith, 2008). In those studies, patients with explicit-memory impairments due to damage to the medial-temporal lobe performed normally in implicit categorization tasks (Bozoki, Grossman, & Smith, 2006;…

Evidence of the preferential use of disease prototypes over case exemplars among early year one medical students prior to and following diagnostic training.

PubMed

Papa, Frank J; Li, Feiming

2015-12-01

Two core dual processing theory (DPT) System I constructs (Exemplars and Prototypes) were used to: 1) formulate a training exercise designed to improve diagnostic performance in year one medical students, and 2) explore whether any observed performance improvements were associated with preferential use of exemplars or prototypes. With IRB approval, 117 year one medical students participated in an acute chest pain diagnostic training exercise. A pre- and post-training test containing the same 27 case vignettes was used to determine if the subjects' diagnostic performance improved via training in both exemplars and prototypes. Exemplar and Prototype theory was also used to generate a unique typicality estimate for each case vignette. Because these estimates produce different performance predictions, differences in the subjects' observed performance would make it possible to infer whether subjects were preferentially using Exemplars or Prototypes. Pre- vs. post-training comparison revealed a significant performance improvement; t=14.04, p<0.001, Cohen's d=1.32. Pre-training, paired t-testing demonstrated that performance against the most typical vignettes>mid typical vignettes: t=4.94, p<0.001; and mid typical>least typical: t=5.16, p<0.001. Post-training, paired t-testing again demonstrated that performance against the most typical vignettes>mid typical: t=2.94, p<0.01; and mid typical>least typical: t=6.64, p<0.001. These findings are more consistent with the performance predictions generated via Prototype theory than Exemplar theory. DPT is useful in designing and evaluating the utility of new approaches to diagnostic training, and, investigating the cognitive factors driving diagnostic capabilities among early medical students.

Remodeling of the Infection Chamber before Infection Thread Formation Reveals a Two-Step Mechanism for Rhizobial Entry into the Host Legume Root Hair1

PubMed Central

Teillet, Alice; Chabaud, Mireille; Ivanov, Sergey; Genre, Andrea; Limpens, Erik; de Carvalho-Niebel, Fernanda; Barker, David G.

2015-01-01

In many legumes, root entry of symbiotic nitrogen-fixing rhizobia occurs via host-constructed tubular tip-growing structures known as infection threads (ITs). Here, we have used a confocal microscopy live-tissue imaging approach to investigate early stages of IT formation in Medicago truncatula root hairs (RHs) expressing fluorescent protein fusion reporters. This has revealed that ITs only initiate 10 to 20 h after the completion of RH curling, by which time major modifications have occurred within the so-called infection chamber, the site of bacterial entrapment. These include the accumulation of exocytosis (M. truncatula Vesicle-Associated Membrane Protein721e)- and cell wall (M. truncatula EARLY NODULIN11)-associated markers, concomitant with radial expansion of the chamber. Significantly, the infection-defective M. truncatula nodule inception-1 mutant is unable to create a functional infection chamber. This underlines the importance of the NIN-dependent phase of host cell wall remodeling that accompanies bacterial proliferation and precedes IT formation, and leads us to propose a two-step model for rhizobial infection initiation in legume RHs. PMID:25659382

Earthquake Advisory Services: A prototype development project

NASA Astrophysics Data System (ADS)

Lagorio, H. J.; Levin, H.

1980-10-01

Development of the prototype Earthquake Advisory Service (EAS) is reported. The EAS is designed to provide direct technical assistance and written materials to advise people who wish to make informed decisions about earthquake hazard reduction in their residences. It is intended also to be adapted to local conditions by community-based agencies. The EAS prototype involved the testing of early assumptions about program implementation, establishment of a systematic methodology review process, and a review of published information pertinent to the project. Operational procedures of the program and the process leading to implementation guidelines are described.

Plant growth chamber M design

NASA Technical Reports Server (NTRS)

Prince, R. P.; Knott, W. M.

1986-01-01

Crop production is just one of the many processes involved in establishing long term survival of man in space. The benefits of integrating higher plants into the overall plan was recognized early by NASA through the Closed Ecological Life Support System (CELSS) program. The first step is to design, construct, and operate a sealed (gas, liquid, and solid) plant growth chamber. A 3.6 m diameter by 6.7 m high closed cylinder (previously used as a hypobaric vessel during the Mercury program) is being modified for this purpose. The chamber is mounted on legs with the central axis vertical. Entrance to the chamber is through an airlock. This chamber will be devoted entirely to higher plant experimentation. Any waste treatment, food processing or product storage studies will be carried on outside of this chamber. Its primary purpose is to provide input and output data on solids, liquids, and gases for single crop species and multiple species production using different nutrient delivery systems.

Studies of Implicit Prototype Extraction In Patients with Mild Cognitive Impairment and Early Alzheimer’s Disease

PubMed Central

Nosofsky, Robert M.; Denton, Stephen E.; Zaki, Safa R.; Murphy-Knudsen, Anne F.; Unverzagt, Frederick W.

2013-01-01

Studies of incidental category learning support the hypothesis of an implicit prototype-extraction system which is distinct from explicit memory (Smith, 2008). In those studies, patients with explicit-memory impairments due to damage to the medial-temporal lobe performed normally in implicit categorization tasks (Bozoki, Grossman, & Smith, 2006; Knowlton & Squire, 1993). However, alternative interpretations are that: i) even people with impairments to a single memory system have sufficient resources to succeed on the particular categorization tasks that have been tested (Nosofsky & Zaki, 1998; Zaki & Nosofsky, 2001); and ii) working memory can be used at time of test to learn the categories (Palmeri & Flanery, 1999). In the present experiments, patients with amnestic mild cognitive impairment or early Alzheimer’s disease were tested in prototype-extraction tasks to examine these possibilities. In a categorization task involving discrete-feature stimuli, the majority of subjects relied on memories for exceedingly few features, even when the task structure strongly encouraged reliance on broad-based prototypes. In a dot-pattern categorization task, even the memory-impaired patients were able to use working memory at time of test to extract the category structure (at least for the stimulus set used in past work). We argue that the results weaken the past case made in favor of a separate system of implicit-prototype extraction. PMID:22746953

Test plan for 32-bit microcomputers for the Water Resources Division; Chapter A, Test plan for acquisition of prototype 32-bit microcomputers

USGS Publications Warehouse

Hutchison, N.E.; Harbaugh, A.W.; Holloway, R.A.; Merk, C.F.

1987-01-01

The Water Resources Division (WRD) of the U.S. Geological Survey is evaluating 32-bit microcomputers to determine how they can complement, and perhaps later replace, the existing network of minicomputers. The WRD is also designing a National Water Information System (NWIS) that will combine and integrate the existing National Water Data Storage and Retrieval System (WATSTORE), National Water Data Exchange (NAWDEX), and components of several other existing systems. The procedures and testing done in a market evaluation of 32-bit microcomputers are documented. The results of the testing are documented in the NWIS Project Office. The market evaluation was done to identify commercially available hardware and software that could be used for implementing early NWIS prototypes to determine the applicability of 32-bit microcomputers for data base and general computing applications. Three microcomputers will be used for these prototype studies. The results of the prototype studies will be used to compile requirements for a Request for Procurement (RFP) for hardware and software to meet the WRD 's needs in the early 1990's. The identification of qualified vendors to provide the prototype hardware and software included reviewing industry literature, and making telephone calls and personal visits to prospective vendors. Those vendors that appeared to meet general requirements were required to run benchmark tests. (Author 's abstract)

Coral Reef Early Warning System (CREWS) RPC Experiment

NASA Technical Reports Server (NTRS)

Estep, Leland; Spruce, Joseph P.; Hall, Callie

2007-01-01

This viewgraph document reviews the background, objectives, methodology, validation, and present status of the Coral Reef Early Warning System (CREWS) Rapid Prototyping Capability (RPC) experiment. The potential NASA contribution to CREWS Decision Support Tool (DST) centers on remotely sensed imagery products.

Review of the development of small- and medium-capacity gas turbines at the Motoren- und Turbinen Union

NASA Technical Reports Server (NTRS)

Heilmann, W.

1985-01-01

Small- and medium-capacity gas turbines under development for turboprop aircraft and helicopter, as well as for armored and commercial vehicle propulsion, are discussed. Design problems related to axial turbines, ceramic components, regenerative gas turbines, and the optimal expansion ratios for turbines with capacities from 250 to greater than 800 kW are considered; in addition, combustion chamber technology is mentioned. Prototype gas turbines with capacities of 500 to 600 kW or 800 to 1800 kW are described.

Behavioral, psychiatric, and sociological problems of long-duration space missions

NASA Technical Reports Server (NTRS)

Kanas, N. A.; Fedderson, W. E.

1971-01-01

A literature search was conducted in an effort to isolate the problems that might be expected on long-duration space missions. Primary sources of the search include short-term space flights, submarine tours, Antarctic expeditions, isolation-chamber tests, space-flight simulators, and hypodynamia studies. Various stressors are discussed including weightlessness and low sensory input; circadian rhythms (including sleep); confinement, isolation, and monotony; and purely psychiatric and sociological considerations. Important aspects of crew selection are also mentioned. An attempt is made to discuss these factors with regard to a prototype mission to Mars.

Gypsum-wallboard formaldehyde-sorption model

DOE Office of Scientific and Technical Information (OSTI.GOV)

Silberstein, S.

1989-11-01

Gypsum wallboard was shown to absorb formaldehyde in a prototype house and in a measuring chamber, as reported previously by researchers at Oak Ridge National Laboratory (ORNL). Also as reported previously, formaldehyde concentrations attained equilibrium in two phases in response to a change in the air exchange rate or to the removal of the formaldehyde source. A rapid initial phase was followed by a slow phase lasting several days. A formaldehyde sorption model that accounts for the biphasic concentration pattern is presented here. Experiments for testing the predictability of the model are proposed.

Advanced Plant Habitat

NASA Image and Video Library

2016-11-17

A test unit, or prototype, of NASA's Advanced Plant Habitat (APH) was delivered to the Space Station Processing Facility at the agency's Kennedy Space Center in Florida. The APH is the largest plant chamber built for the agency. Oscar Monje, a scientist on the Engineering Services Contract, prepares the base of the APH for engineering development tests to see how the science will integrate with the various systems of the plant habitat. The APH will have about 180 sensors and fourt times the light output of Veggie. The APH will be delivered to the International Space Station in March 2017.

Advanced Plant Habitat (APH)

NASA Image and Video Library

2017-03-16

A test unit, or prototype, of NASA's Advanced Plant Habitat (APH) with its first initial grow test in the Space Station Processing Facility at the agency's Kennedy Space Center in Florida. The taller plants pictured are dwarf wheat and the smaller plants are Arabidopsis. Developed by NASA and ORBITEC of Madison, Wisconsin, the APH is the largest plant chamber built for the agency. It is a fully automated plant growth facility that will be used to conduct bioscience research on the International Space Station. The APH will be delivered to the space station aboard future Commercial Resupply Services missions.

Advanced Plant Habitat

NASA Image and Video Library

2016-11-17

A test unit, or prototype, of NASA's Advanced Plant Habitat (APH) was delivered to the Space Station Processing Facility at the agency's Kennedy Space Center in Florida. Inside a laboratory, Engineering Services Contract engineers set up test parameters on computers. From left, are Glenn Washington, ESC quality engineer; Claton Grosse, ESC mechanical engineer; and Jeff Richards, ESC project scientist. The APH is the largest plant chamber built for the agency. It will have 180 sensors and four times the light output of Veggie. The APH will be delivered to the International Space Station in March 2017.

Addendum to `numerical modeling of an enhanced very early time electromagnetic (VETEM) prototype system'

USGS Publications Warehouse

Cui, T.J.; Chew, W.C.; Aydiner, A.A.; Wright, D.L.; Smith, D.V.; Abraham, J.D.

2000-01-01

Two numerical models to simulate an enhanced very early time electromagnetic (VETEM) prototype system that is used for buried-object detection and environmental problems are presented. In the first model, the transmitting and receiving loop antennas accurately analyzed using the method of moments (MoM), and then conjugate gradient (CG) methods with the fast Fourier transform (FFT) are utilized to investigate the scattering from buried conducting plates. In the second model, two magnetic dipoles are used to replace the transmitter and receiver. Both the theory and formulation are correct and the simulation results for the primary magnetic field and the reflected magnetic field are accurate.

On the Prototyping of an ICT-Enhanced Toilet System for Assisting Older Persons Living Independently and Safely at Home.

PubMed

Panek, Paul; Fazekas, Gabor; Lüftenegger, Theresa; Mayer, Peter; Pilissy, Tamas; Raffaelli, Matteo; Rist, Atilla; Rosenthal, Ramona; Savanovic, Arso; Sobjak, Anna; Sonntag, Franziska; Toth, Andras; Unger, Birgit

2017-01-01

Standard toilets often do not meet the needs of a significant number of older persons and persons with disabilities. The EU funded iToilet project aims at design and development of a new type of ICT enhanced modular toilet system which shall be able to support autonomy, dignity and safety of older persons living at home. Methodologically the project started with gathering user requirements by means of questionnaires, interviews and focus group discussion involving a total of 74 persons, thereof 41 subjects with movement disorders (primary users), 21 caregivers (secondary users) and 12 healthcare managers (tertiary users). Most important wishes were bilateral removable handrails, height and tilt adjustment, emergency detection, simplicity. In parallel to the ongoing technical development participatory design activities have been carried out at user test sites in order to continuously involve users into the design process and to allow quick feedback with regards to early prototype parts. The project currently is working on the finalization of the first prototype ready to enter the lab trial stage in spring 2017. The experiences will be used for redesigning a prototype 2 which is planned to be tested in real life settings early 2018.

Performance studies of resistive Micromegas chambers for the upgrade of the ATLAS Muon Spectrometer

NASA Astrophysics Data System (ADS)

Ntekas, Konstantinos

2018-02-01

The ATLAS collaboration at LHC has endorsed the resistive Micromegas technology (MM), along with the small-strip Thin Gap Chambers (sTGC), for the high luminosity upgrade of the first muon station in the high-rapidity region, the so called New Small Wheel (NSW) project. The NSW requires fully efficient MM chambers, up to a particle rate of ˜ 15 kHz/cm2, with spatial resolution better than 100 μm independent of the track incidence angle and the magnetic field (B ≤ 0.3 T). Along with the precise tracking the MM should be able to provide a trigger signal, complementary to the sTGC, thus a decent timing resolution is required. Several tests have been performed on small (10 × 10 cm2) MM chambers using medium (10 GeV/c) and high (150 GeV/c) momentum hadron beams at CERN. Results on the efficiency and position resolution measured during these tests are presented demonstrating the excellent characteristics of the MM that fulfil the NSW requirements. Exploiting the ability of the MM to work as a Time Projection Chamber a novel method, called the μTPC, has been developed for the case of inclined tracks, allowing for a precise segment reconstruction using a single detection plane. A detailed description of the method along with thorough studies towards refining the method's performance are shown. Finally, during 2014 the first MM quadruplet (MMSW) following the NSW design scheme, comprising four detection planes in a stereo readout configuration, has been realised at CERN. Test-beam results of this prototype are discussed and compared to theoretical expectations.

SU-E-I-107: Suitability of Various Radiation Detectors Used in Radiation Therapy for X-Ray Dosimetry in Computed Tomography.

PubMed

Liebmann, M; Poppe, B; von Boetticher, H

2012-06-01

Assessment of suitability for X-ray dosimetry in computed tomography of various ionization chambers, diodes and two-dimensional detector arrays primarily used in radiation therapy. An Oldelft X-ray simulation unit was used to irradiate PTW 60008, 60012 dosimetry diodes, PTW 23332, 31013, 31010, 31006 axial symmetrical ionization chambers, PTW 23343, 34001 plane parallel ionization chambers and PTW Starcheck and 2D-Array seven29 as well as a prototype Farmer chamber with a copper wall. Peak potential was varied from 50 kV up to 125 kV and beam qualities were quantified through half-value-layer measurements. Energy response was investigated free in air as well as in 2 cm depth in a solid water phantom and refers to a manufacturer calibrated PTW 60004 diode for kV-dosimetry. The thimble ionization chambers PTW 31010, 31013, the uncapsuled diode PTW 60012 and the PTW 2D-Array seven29 exhibit an energy response deviation in the investigated energy region of approximately 10% or lower thus proving good usability in X-ray dosimetry if higher spatial resolution is needed or rotational irradiations occur. It could be shown that in radiation therapy routinely used detectors are usable in a much lower energy region. The rotational symmetry is of advantage in computed tomography dosimetry and enables dose profile as well as point dose measurements in a suitable phantom for estimation of organ doses. Additional the PTW 2D-Array seven29 can give a quick overview of radiation fields in non-rotating tasks. © 2012 American Association of Physicists in Medicine.

Paper prototypes for the detection of stereotype violations in (medical) device operation - are they good enough?

PubMed

Hallbeck, M Susan; Koneczny, Sonja; Smith, Justine

2009-01-01

Controls for most technologies, including medical devices, are becoming increasingly complex, difficult to intuitively understand and don't necessarily follow population stereotypes. The resulting delays and errors are unacceptable when seconds can mean the difference between life and death. In this study participants were asked to "control" a system using a paper prototype (color photographs of controls) and then with a higher fidelity prototype of the same physical controls to determine performance differences among ethnicities and genders. No ethnic nor gender differences were found, and the comparison of paper versus higher fidelity prototypes also showed no significant differences. Thus, paper prototypes can be employed as an early device design usability tool to illustrate stereotype violations long before the first physical prototype. This will not only save money in the development and design processes, but also makes sure that even the most complex devices are intuitively understandable and operable for their basic functions.

The Biology and Ecology of the Emerald Ash Borer, Agrilus planipennis, in China

PubMed Central

Wang, Xiao-Yi; Yang, Zhong-Qi; Gould, Juli R.; Zhang, Yi-Nan; Liu, Gui-Jun; Liu, EnShan

2010-01-01

The biology, ecology, and life cycle of the emerald ash borer, Agrilus planipennis Fairmaire (Coleoptera: Buprestidae), were studied using regular inspection in the forest and observations in the laboratory. Results indicated that A. planipennis are mostly univoltine in Tianjin, China. They overwintered individually as mature larvae in shallow chambers excavated in the outer sapwood. In late July, some full-grown larvae began to build overwintering chambers, and all larvae entered the sapwood for dormancy by early November. A. planipennis pupated in the overwintering chamber from early April to mid May the following year, and the average pupal duration was about 20 days. In late April, some newly eclosed adults could be found in the pupal cells, but they had not yet emerged from the tree. Adults began to emerge in early May, with peak flight occurring in mid May. The average longevity of adults was about 21 days and the adult stage lasted through early July. The adults fed on ash foliage as a source of nutrition. Mating was usually conducted and completed on the leaf or trunk surfaces of ash trees. Oviposition began in mid May and eggs hatched on average in 15.7 days. The first instar larvae appeared in early June. The larval stage lasted about 300 days to complete an entire generation. The emerald ash borer had four larval instars on velvet ash, Fraxinus velutina (Scrophulariales: Oleaceae). The major natural control factors of A. planipennis were also investigated, and preliminary suggestions for its integrated management are proposed. PMID:20879922

The biology and ecology of the emerald ash borer, Agrilus planipennis, in China.

PubMed

Wang, Xiao-Yi; Yang, Zhong-Qi; Gould, Juli R; Zhang, Yi-Nan; Liu, Gui-Jun; Liu, En-shan

2010-01-01

The biology, ecology, and life cycle of the emerald ash borer, Agrilus planipennis Fairmaire (Coleoptera: Buprestidae), were studied using regular inspection in the forest and observations in the laboratory. Results indicated that A. planipennis are mostly univoltine in Tianjin, China. They overwintered individually as mature larvae in shallow chambers excavated in the outer sapwood. In late July, some full-grown larvae began to build overwintering chambers, and all larvae entered the sapwood for dormancy by early November. A. planipennis pupated in the overwintering chamber from early April to mid May the following year, and the average pupal duration was about 20 days. In late April, some newly eclosed adults could be found in the pupal cells, but they had not yet emerged from the tree. Adults began to emerge in early May, with peak flight occurring in mid May. The average longevity of adults was about 21 days and the adult stage lasted through early July. The adults fed on ash foliage as a source of nutrition. Mating was usually conducted and completed on the leaf or trunk surfaces of ash trees. Oviposition began in mid May and eggs hatched on average in 15.7 days. The first instar larvae appeared in early June. The larval stage lasted about 300 days to complete an entire generation. The emerald ash borer had four larval instars on velvet ash, Fraxinus velutina (Scrophulariales: Oleaceae). The major natural control factors of A. planipennis were also investigated, and preliminary suggestions for its integrated management are proposed.

A new environment for multiple spacecraft power subsystem mission operations

NASA Technical Reports Server (NTRS)

Bahrami, K. A.

1990-01-01

The engineering analysis subsystem environment (EASE) is being developed to enable fewer controllers to monitor and control power and other spacecraft engineering subsystems. The EASE prototype has been developed to support simultaneous real-time monitoring of several spacecraft engineering subsystems. It is being designed to assist with offline analysis of telemetry data to determine trends, and to help formulate uplink commands to the spacecraft. An early version of the EASE prototype has been installed in the JPL Space Flight Operations Facility for online testing. The EASE prototype is installed in the Galileo Mission Support Area. The underlying concept, development, and testing of the EASE prototype and how it will aid in the ground operations of spacecraft power subsystems are discussed.

Microflora inside closed modules with plant growth facility

NASA Astrophysics Data System (ADS)

Zyablova, Natalya V.; Berkovich, Yuliy A.; Shanturin, Nikolai; Deshevaya, Elena; Smolyanina, Svetlana O.

Currently, plant growth facility (PGF) is included in the LSS in many scenarios of Martian expedition. A number of investigators assume growing of crops can accelerate microflora re-production in closed ecological system. To estimate experimentally the change of density of microbiological community in the isolated module, Chinese cabbage Brassica hinensis L., cv. Vesnyanka, has been grown in the closed climatic chambers in volume 0.07 m3, 3 m3 and 250 m3 under continuous illumination in the range of values of temperature and relative humidity of air 23 -270 and 30 -60%, respectively. There were no differences in growth and develop-ment of plants grown during 30 days on the test-beds in the laboratory room (control) and in the closed chamber by 0.07 m3 volume (test). The microbiological analysis of root zone has revealed the presence of exclusively saprophytic species -the typical representatives of the soil microbiota. Then the plants were growing during 45 days in the prototype of the conveyor space PGF "Phytocycle LED" placed inside the chamber of 3 m3 volume. Every 3 days 50 -60 cm3 of liquid imitator of air condensate (IAC) from inhabited module had been injected to the chamber to simulate air pollution. The content of colony-forming units of the micromycetes in the air of the chamber, on the inner surfaces of the climate chamber, internal and external surfaces of the PGF and the leaves did not exceed the permissible values. When the PGF has been installed during 14 days inside the inhabited module with volume of 250 m3, the representatives of saprophytic and conditioned-pathogenic species of micromycetes (Trichethe-cium rozeum, Trichoderma sp., Fuzarrium sp., Mucor sp., Penicillium sp.) have been found out exclusively on the open surfaces of artificial soil and water-saturated porous passage. The obtained data shows that PGF inside closed modules can assure microbiological safety when all wet surfaces are isolated from the gas environment.

An online proton beam monitor for cancer therapy based on ionization chambers with micro pattern readout

NASA Astrophysics Data System (ADS)

Basile, E.; Carloni, A.; Castelluccio, D. M.; Cisbani, E.; Colilli, S.; De Angelis, G.; Fratoni, R.; Frullani, S.; Giuliani, F.; Gricia, M.; Lucentini, M.; Santavenere, F.; Vacca, G.

2012-03-01

A unique compact LINAC accelerator for proton therapy is under development in Italy within the TOP-IMPLART project. The proton beam will reach the kinetic energy of 230 MeV, it will have a widely variable current intensity (0.1-10 μA, with average up to 3.5 nA) associated with a high pulse repetition frequency (1-3.5 μs long pulses at 10-100 Hz). The TOP-IMPLART system will provide a fully active 3+1D dose delivery, that is longitudinal (energy modulation), transverse active spot scanning, and current intensity modulation. These accelerator features will permit a highly conformational dose distribution, which therefore requires an effective, online, beam monitor system with wide dynamic range, good sensitivity, adequate spatial resolution and rapid response. In order to fulfill these requisites a new device is under development for the monitoring of the beam intensity profile, its centroid and direction; it is based on transmission, segmented, ionization chambers with typical active area of 100 × 100 mm2. Micro pattern x/y pad like design has been used for the readout plane in order to maximize the field uniformity, reduce the chamber thickness and obtain both beam coordinates on a single chamber. The chamber prototype operates in ionization region to minimize saturation and discharge effects. Simulations (based on FLUKA) have been carried on to study the perturbation of the chamber on the beam parameters and the effects on the delivered dose (on a water phantom). The charge collected in each channel is integrated by dedicated auto-ranging readout electronics: an original scheme has been developed in order to have an input dynamic range greater than 104 with sensitivity better than 3%. This is achieved by a dynamical adjustment of the integrating capacitance to the signal intensity.

Sexual dimorphism of the internal mandibular chamber in Fayum Pliohyracidae (Mammalia)

USGS Publications Warehouse

de Blieux, D.D.; Baumrind, M.R.; Simons, E.L.; Chatrath, P.S.; Meyer, G.E.; Attia, Y.S.

2006-01-01

An internal mandibular fenestra and chamber are found in many fossil hyracoids. The internal mandibular fenestra is located on the lingual surface of the mandibular corpus and opens into a chamber within the mandible. The mandibular chamber is maximally developed in late Eocene Thyrohyrax meyeri and early Oligocene Thyrohyrax domorictus from the Fayum Province of Egypt. The function of this chamber is unknown as it is not found in extant hyraxes, nor is it known to occur in any other mammal. In Thyrohyrax, this feature appears to be sexually dimorphic because it is confined to roughly one half of the specimens that otherwise cannot be separated by dental characteristics or measurements. It has been suggested that the chamber is found in females based on the presumed distribution of this character in other fossil hyracoids. Fossils from Fayum Quarry L-41, preserving the sexually dimorphic anterior dentition, show that, in Thyrohyrax meyeri and Thyrohyrax domorictus, the internal mandibular chamber is found in males. In Thyrohyrax litholagus, an internal mandibular fenestra and inflated mandibular chamber occurs in males whereas females show the variable presence of an internal mandibular fossa or fenestra but lack an expanded chamber. Other genera show differing patterns of sexual variation in which some Fayum hyracoids have an internal mandibular fenestra in both sexes but with the greatest development of the mandibular chamber occurring in males. We review functions proposed for the internal mandibular chamber and suggest that it housed a laryngeal air sac that may have had a vocal function by acting as a resonating chamber. ?? 2006 by the Society of Vertebrate Paleontology.

Improving the accuracy of ionization chamber dosimetry in small megavoltage x-ray fields

NASA Astrophysics Data System (ADS)

McNiven, Andrea L.

The dosimetry of small x-ray fields is difficult, but important, in many radiation therapy delivery methods. The accuracy of ion chambers for small field applications, however, is limited due to the relatively large size of the chamber with respect to the field size, leading to partial volume effects, lateral electronic disequilibrium and calibration difficulties. The goal of this dissertation was to investigate the use of ionization chambers for the purpose of dosimetry in small megavoltage photon beams with the aim of improving clinical dose measurements in stereotactic radiotherapy and helical tomotherapy. A new method for the direct determination of the sensitive volume of small-volume ion chambers using micro computed tomography (muCT) was investigated using four nominally identical small-volume (0.56 cm3) cylindrical ion chambers. Agreement between their measured relative volume and ionization measurements (within 2%) demonstrated the feasibility of volume determination through muCT. Cavity-gas calibration coefficients were also determined, demonstrating the promise for accurate ion chamber calibration based partially on muCT. The accuracy of relative dose factor measurements in 6MV stereotactic x-ray fields (5 to 40mm diameter) was investigated using a set of prototype plane-parallel ionization chambers (diameters of 2, 4, 10 and 20mm). Chamber and field size specific correction factors ( CSFQ ), that account for perturbation of the secondary electron fluence, were calculated using Monte Carlo simulation methods (BEAM/EGSnrc simulations). These correction factors (e.g. CSFQ = 1.76 (2mm chamber, 5mm field) allow for accurate relative dose factor (RDF) measurement when applied to ionization readings, under conditions of electronic disequilibrium. With respect to the dosimetry of helical tomotherapy, a novel application of the ion chambers was developed to characterize the fan beam size and effective dose rate. Characterization was based on an adaptation of the computed tomography dose index (CTDI), a concept normally used in diagnostic radiology. This involved experimental determination of the fan beam thickness using the ion chambers to acquire fan beam profiles and extrapolation to a 'zero-size' detector. In conclusion, improvements have been made in the accuracy of small field dosimetry measurements in stereotactic radiotherapy and helical tomotherapy. This was completed through introduction of an original technique involving micro-CT imaging for sensitive volume determination and potentially ion chamber calibration coefficients, the use of appropriate Monte Carlo derived correction factors for RDF measurement, and the exploitation of the partial volume effect for helical tomotherapy fan beam dosimetry. With improved dosimetry for a wide range of challenging small x-ray field situations, it is expected that the patient's radiation safety will be maintained, and that clinical trials will adopt calibration protocols specialized for modern radiotherapy with small fields or beamlets. Keywords. radiation therapy, ionization chambers, small field dosimetry, stereotactic radiotherapy, helical tomotherapy, micro-CT.

Designing a Mobile Health Application Prototype for the Management of Interstitial Cystitis/Painful Bladder Syndrome.

PubMed

Griffith, Janessa

2017-01-01

The design of an early mobile health application (app) prototype to manage interstitial cystitis/painful bladder syndrome, a chronic condition characterized by recurrent pain/discomfort in the bladder and pelvic floor, is described. The purpose of this app prototype is to help people who have IC/PBS manage and learn what triggers their symptoms. Another aim of this research was to provide an example of how sex and gender could be included into the design of a health information system. Based on a literature search of common symptoms and challenges faced by people living with IC/PBS, the researcher created an app prototype design including many features: resources for relaxation, mental health, intimacy, pregnancy, and daily life; reminders for appointments, and medication; logs for diet, activity, sleep, pain, menstruation; and a link to a public washroom locator. This prototype will later undergo usability and content evaluation.

Influencing Gameplay in Support of Early Synthetic Prototyping Studies

DTIC Science & Technology

2016-06-01

Synthetic Prototyping, acquisition, video games, crowdsourcing, Engineering Resilient Systems, science and technology, game environment 15. NUMBER OF...even though he did not play video games for entertainment, he would find time to participate in ESP (Vogt, Megiveron, & Smith, 2015). Meckler’s...reward used in video games: 1) score systems, 2) experience points, 3) item granting, 4) collectible resources, 5) achievement systems, 6) feedback

Environmental qualification testing of payload G-534, the Pool Boiling Experiment

NASA Technical Reports Server (NTRS)

Sexton, J. Andrew

1992-01-01

Payload G-534, the prototype Pool Boiling Experiment (PBE), is scheduled to fly on the STS-47 mission in September 1992. This paper describes the purpose of the experiment and the environmental qualification testing program that was used to prove the integrity of the hardware. Component and box level vibration and thermal cycling tests were performed to give an early level of confidence in the hardware designs. At the system level, vibration, thermal extreme soaks, and thermal vacuum cycling tests were performed to qualify the complete design for the expected shuttle environment. The system level vibration testing included three axis sine sweeps and random inputs. The system level hot and cold soak tests demonstrated the hardware's capability to operate over a wide range of temperatures and gave wider latitude in determining which shuttle thermal attitudes were compatible with the experiment. The system level thermal vacuum cycling tests demonstrated the hardware's capability to operate in a convection free environment. A unique environmental chamber was designed and fabricated by the PBE team and allowed most of the environmental testing to be performed within the hardware build laboratory. The completion of the test program gave the project team high confidence in the hardware's ability to function as designed during flight.

Pressure increases, the formation of chromite seams, and the development of the ultramafic series in the Stillwater Complex, Montana

USGS Publications Warehouse

Lipin, B.R.

1993-01-01

This paper explores the hypothesis that chromate seams in the Stillwater Complex formed in response to periodic increases in total pressure in the chamber. Total pressure increased because of the positive ??V of nucleation of CO2 bubbles in the melt and their subsequent rise through the magma chamber, during which the bubbles increased in volume by a factor of 4-6. By analogy with the pressure changes in the summit chambers of Kilauea and Krafla volcanoes, the maximum variation was 0.2-0.25 kbar, or 5-10% of the total pressure in the Stillwater chamber. An evaluation of the likelihood of fountaining and mixing of a new, primitive liquid that entered the chamber with the somewhat more evolved liquid already in the chamber is based upon calculations using observed and inferred velocities and flow rates of basaltic magmas moving through volcanic fissures. The calculations indicate that hot, dense magma would have oozed, rather than fountained into the chamber, and early mixing of the new and residual magmas that could have resulted in chromite crystallizing alone did not take place. -from Author

Detection of congenital heart defects throughout pregnancy; impact of first trimester ultrasound screening for cardiac abnormalities.

PubMed

Eleftheriades, Makarios; Tsapakis, Elsa; Sotiriadis, Alexandros; Manolakos, Emmanouil; Hassiakos, Demetrios; Botsis, Demetrios

2012-12-01

To evaluate prospectively the efficacy to screen for congenital heart defects (CHD) during the first trimester nuchal translucency (NT) ultrasound examination by assessing the four chambers' view of fetal heart. Pregnancies that were examined prospectively by ultrasound in the first trimester (11th-14th week), the second (19th-24th week) and third trimester were included in the study. 3774 fetuses were examined and fetal heart was assessed during the NT scan by examining the four chambers view. Detailed echocardiography was performed during the anomaly and growth scans. Diagnosis of congenital heart defects (CHD) was further confirmed by a fetal cardiologist. The four chambers view was obtained in 99.52% of the cases. CHD were diagnosed in 29 fetuses (0.77%). Thirteen cases (44.8%) were detected during the 11-13 weeks' scan, 14 cases (48.3%) during the anomaly scan, 1 CHD (3.5%) during the third trimester scan and 1 case (3.5%) postpartum. Assessment of the four chambers of fetal heart early in pregnancy was feasible and allowed the detection of 45% of CHD. Additional parameters of fetal cardiac anatomy during the NT scan may further improve the detection rate providing pregnancy management information early in the first trimester.

Development of the gravid Aedes trap for the capture of adult female container-exploiting mosquitoes (Diptera: Culicidae).

PubMed

Eiras, Alvaro E; Buhagiar, Tamara S; Ritchie, Scott A

2014-01-01

Monitoring dengue vector control by sampling adult Aedes aegypti (L.) recently has been used to replace both larval and pupal surveys. We have developed and evaluated the Gravid Aedes Trap (GAT) through a sequential behavioral study. The GAT does not require electricity to function, and trapped mosquitoes are identified easily during trap inspections. The GAT concept relies on visual and olfactory cues to lure gravid Ae. aegypti and an insecticide to kill trapped mosquitoes. Gravid mosquitoes are lured to a black bucket base containing oviposition attractant (infusion) and are trapped in a translucent chamber impregnated with a pyrethroid insecticide where they are killed within 3-15 min. In semifield observations, the GAT captured a significantly higher proportion of gravid mosquitoes than the double sticky ovitrap. We also demonstrated that the visual cues of the prototype GAT-LgBF (large black base bucket with a black funnel at the top of the translucent chamber) captured a significantly higher proportion of gravid mosquitoes than the other prototypes. The visual contrast created by the addition of a white lid to the top of the black funnel significantly increased the number of captured gravid mosquitoes when compared with the GAT-LgBF in semifield trials. We conclude that the GAT is more efficient in recapturing gravid Ae. aegypti when compared with sticky ovitraps. The GAT is an effective, practical, low cost, and easily transportable trap, features that are essential in large-scale monitoring programs, particularly in areas where funding is limited.

In Vitro Capture of Small Ferrous Particles with a Magnetic Filtration Device Designed for Intravascular Use with Intraarterial Chemotherapy: Proof-of-Concept Study

PubMed Central

Mabray, Marc C.; Lillaney, Prasheel; Sze, Chia-Hung; Losey, Aaron D.; Yang, Jeffrey; Kondapavulur, Sravani; Liu, Derek; Saeed, Maythem; Patel, Anand; Cooke, Daniel; Jun, Young-Wook; El-Sayed, Ivan; Wilson, Mark; Hetts, Steven W.

2015-01-01

Purpose To establish that a magnetic device designed for intravascular use can bind small iron particles in physiologic flow models. Materials and Methods Uncoated iron oxide particles 50–100 nm and 1–5 μm in size were tested in a water flow chamber over a period of 10 minutes without a magnet (ie, control) and with large and small prototype magnets. These same particles and 1-μm carboxylic acid–coated iron oxide beads were likewise tested in a serum flow chamber model without a magnet (ie, control) and with the small prototype magnet. Results Particles were successfully captured from solution. Particle concentrations in solution decreased in all experiments (P < .05 vs matched control runs). At 10 minutes, concentrations were 98% (50–100-nm particles in water with a large magnet), 97% (50–100-nm particles in water with a small magnet), 99% (1–5-μm particles in water with a large magnet), 99% (1–5-μm particles in water with a small magnet), 95% (50–100-nm particles in serum with a small magnet), 92% (1–5-μm particles in serum with a small magnet), and 75% (1-μm coated beads in serum with a small magnet) lower compared with matched control runs. Conclusions This study demonstrates the concept of magnetic capture of small iron oxide particles in physiologic flow models by using a small wire-mounted magnetic filter designed for intravascular use. PMID:26706187

A Regeneratively Cooled Thrust Chamber For The Fastrac Engine

NASA Technical Reports Server (NTRS)

Brown, Kendall K.; Sparks, Dave; Woodcock, Gordon

2000-01-01

Abstract This paper presents the development of a low-cost, regeneratively-cooled thrust chamber for the Fastrac engine. The chamber was fabricated using hydraformed copper tubing to form the coolant jacket and wrapped with a fiber reinforced polymer composite Material to form a structural jacket. The thrust chamber design and fabrication approach was based upon Space America. Inc.'s 12,000 lb regeneratively-cooled LOX/kerosene rocket engine. Fabrication of regeneratively cooled thrust chambers by tubewall construction dates back to the early US ballistic missile programs. The most significant innovations in this design was the development of a low-cost process for fabrication from copper tubing (nickel alloy was the usual practice) and use of graphite composite overwrap as the pressure containment, which yields an easily fabricated, lightweight pressure jacket around the copper tubes A regeneratively-cooled reusable thrust chamber can benefit the Fastrac engine program by allowing more efficient (cost and scheduler testing). A proof-of-concept test article has been fabricated and will he tested at Marshall Space Flight Center in the late Summer or Fall of 2000.

Ignition characterization of LOX/hydrocarbon propellants

NASA Technical Reports Server (NTRS)

Lawver, B. R.; Rousar, D. C.; Wong, K. Y.

1985-01-01

The results of an evaluation of the ignition characteristics of the gaseous oxygen (Gox)/Ethanol propellant combination are presented. Ignition characterization was accomplished through the analysis, design, fabrication and testing of a spark initiated torch igniter and prototype 620 lbF thruster/igniter assembly. The igniter was tested over a chamber pressure range of 74 to 197 psia and mixture ratio range of 0.778 to 3.29. Cold (-92 to -165 F) and ambient (44 to 80 F) propellant temperatures were used. Spark igniter ignition limits and thruster steady state and pulse mode, performance, cooling and stability data are presented. Spark igniter ignition limits are presented in terms of cold flow pressure, ignition chamber diameter and mixture ratio. Thruster performance is presented in terms of vacuum specific impulse versus engine mixture ratio. Gox/Ethanol propellants were shown to be ignitable over a wide range of mixture ratios. Cold propellants were shown to have a minor effect on igniter ignition limits. Thruster pulse mode capability was demonstrated with multiple pulses of 0.08 sec duration and less.

Development of 10B-Based 3He Replacement Neutron Detectors

NASA Astrophysics Data System (ADS)

King, Michael J.; Gozani, Tsahi; Hilliard, Donald B.

2011-12-01

Radiation portal monitors (RPM) are currently deployed at United States border crossings to passively inspect vehicles and persons for any emission of neutrons and/or gamma rays, which may indicate the presence of unshielded nuclear materials. The RPM module contains an organic scintillator with 3He proportional counters to detect gamma rays and thermalized neutrons, respectively. The supply of 3He is rapidly dwindling, requiring alternative detectors to provide the same function and performance. Our alternative approach is one consisting of a thinly-coated 10B flat-panel ionization chamber neutron detector that can be deployed as a direct drop-in replacement for current RPM 3He detectors. The uniqueness of our approach in providing a large-area detector is in the simplicity of construction, scalability of the unit cell detector, ease of adaptability to a variety of applications and low cost. Currently, Rapiscan Laboratories and Helicon Thin Film Systems have designed and developed an operational 100 cm2 multi-layer prototype 10BB-based ionization chamber.

Testing of multigap Resistive Plate Chambers for Electron Ion Collider Detector Development

NASA Astrophysics Data System (ADS)

Hamilton, Hannah; Phenix Collaboration

2015-10-01

Despite decades of research on the subject, some details of the spin structure of the nucleon continues to be unknown. To improve our knowledge of the nucleon spin structure, the construction of a new collider is needed. This is one of the primary goals of the proposed Electron Ion Collider (EIC). Planned EIC spectrometers will require good particle identification. This can be provided by time of flight (TOF) detectors with excellent timing resolutions of 10 ps. A potential TOF detector that could meet this requirement is a glass multigap resistive plate chamber (mRPC). These mRPCs can provide excellent timing resolution at a low cost. The current glass mRPC prototypes have a total of twenty 0.1 mm thick gas gaps. In order to test the feasibility of this design, a cosmic test stand was assembled. This stand used the coincidence of scintillators as a trigger, and contains fast electronics. The construction, the method of testing, and the test results of the mRPCs will be presented.

A cylindrical tripleGEM detector for the BESIII experiment: Measurement of the performance in a magnetic field and project status

NASA Astrophysics Data System (ADS)

Farinelli, R.; BESIII CGEM Group

2017-01-01

A new cylindrical GEM detector is under development to upgrade the tracking system of the BESIII experiment at the IHEP in Beijing. The new detector will replace the current inner drift chamber of the experiment in order to increase significantly the spatial resolution along the beam direction (σ_z ˜ 300 μ m) and to grant the performance of momentum resolution (σ_{p_t}/p_t ˜ 0.5% at 1GeV) and spatial resolution (σ_{xy} ˜ 130 μ m). A cylindrical prototype with the final detector dimensions has been built and the assembly procedure has been successfully validated. Moreover the performance of a 10 × 10 cm ^2 planar GEM has been studied inside a magnetic field by means of a beam test at CERN. The data have been analyzed using two different readout mode: the charge centroid (CC) and the micro time projection chamber ( μ TPC) method.

A pixelated charge readout for Liquid Argon Time Projection Chambers

NASA Astrophysics Data System (ADS)

Asaadi, J.; Auger, M.; Ereditato, A.; Goeldi, D.; Hänni, R.; Kose, U.; Kreslo, I.; Lorca, D.; Luethi, M.; von Rohr, C. Rudolf; Sinclair, J.; Stocker, F.; Tognina, C.; Weber, M.

2018-02-01

Liquid Argon Time Projection Chambers (LArTPCs) are ideally suited to perform long-baseline neutrino experiments aiming to measure CP violation in the lepton sector, and determine the ordering of the three neutrino mass eigenstates. LArTPCs have used projective wire readouts for charge detection since their conception in 1977. However, wire readouts are notoriously fragile and therefore a limiting factor in the design of any large mass detectors. Furthermore, a wire readout also introduces intrinsic ambiguities in event reconstruction. Within the ArgonCube concept—the liquid argon component of the DUNE near detector—we are developing a pixelated charge readout for LArTPCs. Pixelated charge readout systems represent the single largest advancement in the sensitivity of LArTPCs. They are mechanically robust and provide direct 3D readout, serving to minimise reconstruction ambiguities, enabling more advanced triggers, further reducing event pile-up and improving background rejection. This article presents first results from a pixelated LArTPC prototype built and operated in Bern.

Multipole gas thruster design. Ph.D. Thesis

NASA Technical Reports Server (NTRS)

Isaacson, G. C.

1977-01-01

The development of a low field strength multipole thruster operating on both argon and xenon is described. Experimental results were obtained with a 15-cm diameter multipole thruster and are presented for a wide range of discharge-chamber configurations. Minimum discharge losses were 300-350 eV/ion for argon and 200-250 eV/ion for xenon. Ion beam flatness parameters in the plane of the accelerator grid ranged from 0.85 to 0.93 for both propellants. Thruster performance is correlated for a range of ion chamber sizes and operating conditions as well as propellant type and accelerator system open area. A 30-cm diameter ion source designed and built using the procedure and theory presented here-in is shown capable of low discharge losses and flat ion-beam profiles without optimization. This indicates that by using the low field strength multipole design, as well as general performance correlation information provided herein, it should be possible to rapidly translate initial performance specifications into easily fabricated, high performance prototypes.

Lifetime Estimation of a Time Projection Chamber X-ray Polarimeter

NASA Technical Reports Server (NTRS)

Hill, Joanne E.; Black, J. Kevin; Brieda, Lubos; Dickens, Patsy L.; deGarcia, Kristina Montt; Hawk, Douglas L.; Hayato, Asami; Jahoda, Keith; Mohammed, Jelila

2013-01-01

The Gravity and Extreme Magnetism Small Explorer (GEMS) X-ray polarimeter Instrument (XPI) was designed to measure the polarization of 23 sources over the course of its 9 month mission. The XPI design consists of two telescopes each with a polarimeter assembly at the focus of a grazing incidence mirror. To make sensitive polarization measurements the GEMS Polarimeter Assembly (PA) employed a gas detection system based on a Time Projection Chamber (TPC) technique. Gas detectors are inherently at risk of degraded performance arising from contamination from outgassing of internal detector components or due to loss of gas. This paper describes the design and the materials used to build a prototype of the flight polarimeter with the required GEMS lifetime. We report the results from outgassing measurements of the polarimeter subassemblies and assemblies, enclosure seal tests, life tests, and performance tests that demonstrate that the GEMS lifetime is achievable. Finally we report performance measurements and the lifetime enhancement from the use of a getter.

Resistive Plate Chambers as thermal neutron detectors

NASA Astrophysics Data System (ADS)

Abbrescia, M.; Mongelli, T.; Paticchio, V.; Ranieri, A.; Trentadue, R.

2003-09-01

We present a construction procedure suitable to make Resistive Plate Chambers detectors sensitive also to thermal neutrons. This procedure, consisting in coating the inner surface of one of the RPC Bakelite electrodes with a mixture of linseed oil and Gd203, is very simple, cheap, and suitable to be employed for industrial, medical or de-mining applications. Here the results of extensive tests aimed to asset the performance of two prototypes of Gd-RPCs are shown. While the detection efficiency to thermal neutrons for a standard not Gd-coated RPC results to be about 0.1%, Gd-RPCs reach, in stand-alone, absolute efficiencies of about 10%, and, when two of these detectors are coupled together, more than 15%. In addition RPCs have excellent time resolution and good imaging performance. This new type, position sensitive gas detector can be operated at atmospheric pressure, is light-weighted, has low γ-ray sensitivity, and is easy to build and handle even when large areas are to be covered.

An ion source for radiofrequency-pulsed glow discharge time-of-flight mass spectrometry

NASA Astrophysics Data System (ADS)

González Gago, C.; Lobo, L.; Pisonero, J.; Bordel, N.; Pereiro, R.; Sanz-Medel, A.

2012-10-01

A Grimm-type glow discharge (GD) has been designed and constructed as an ion source for pulsed radiofrequency GD spectrometry when coupled to an orthogonal time of flight mass spectrometer. Pulse shapes of argon species and analytes were studied as a function of the discharge conditions using a new in-house ion source (UNIOVI GD) and results have been compared with a previous design (PROTOTYPE GD). Different behavior and shapes of the pulse profiles have been observed for the two sources evaluated, particularly for the plasma gas ionic species detected. In the more analytically relevant region (afterglow), signals for 40Ar+ with this new design were negligible, while maximum intensity was reached earlier in time for 41(ArH)+ than when using the PROTOTYPE GD. Moreover, while maximum 40Ar+ signals measured along the pulse period were similar in both sources, 41(ArH)+ and 80(Ar2)+ signals tend to be noticeable higher using the PROTOTYPE chamber. The UNIOVI GD design was shown to be adequate for sensitive direct analysis of solid samples, offering linear calibration graphs and good crater shapes. Limits of detection (LODs) are in the same order of magnitude for both sources, although the UNIOVI source provides slightly better LODs for those analytes with masses slightly higher than 41(ArH)+.

MIXS on BepiColombo and its DEPFET based focal plane instrumentation

NASA Astrophysics Data System (ADS)

Treis, J.; Andricek, L.; Aschauer, F.; Heinzinger, K.; Herrmann, S.; Hilchenbach, M.; Lauf, T.; Lechner, P.; Lutz, G.; Majewski, P.; Porro, M.; Richter, R. H.; Schaller, G.; Schnecke, M.; Schopper, F.; Soltau, H.; Stefanescu, A.; Strüder, L.; de Vita, G.

2010-12-01

Focal plane instrumentation based on DEPFET Macropixel devices, being a combination of the Detector-Amplifier structure DEPFET with a silicon drift chamber (SDD), has been proposed for the MIXS (Mercury Imaging X-ray Spectrometer) instrument on ESA's Mercury exploration mission BepiColombo. MIXS images X-ray fluorescent radiation from the Mercury surface with a lightweight X-ray mirror system on the focal plane detector to measure the spatially resolved element abundance in Mercury's crust. The sensor needs to have an energy resolution better than 200 eV FWHM at 1 keV and is required to cover an energy range from 0.5 to 10 keV, for a pixel size of 300×300μm2. Main challenges for the instrument are radiation damage and the difficult thermal environment in the mercury orbit. The production of the first batch of flight devices has been finished at the MPI semiconductor laboratory. Prototype modules have been assembled to verify the electrical properties of the devices; selected results are presented here. The prototype devices, Macropixel prototypes for the SIMBOL-X focal plane, are electrically fully compatible, but have a pixel size of 0.5×0.5 mm2. Excellent homogeneity and near Fano-limited energy resolution at high readout speeds have been observed on these devices.

Study of a Large Prototype TPC for the ILC using Micro-Pattern Gas Detectors

NASA Astrophysics Data System (ADS)

Münnich, A.; LCTPC Collaboration

2016-04-01

In the last decade, R&D for detectors for the future International Linear Collider (ILC) has been performed by the community. The International Large Detector (ILD) is one of two detector concepts at the ILC. Its tracking system consists of a Si vertex detector, forward tracking disks and a large volume Time Projection Chamber (TPC). Within the LCTPC collaboration, a Large Prototype (LP) TPC has been built as a demonstrator. Its endplate is able to house up to seven identical modules with Micro-Pattern Gas Detectors (MPGD) amplification. Recently, the LP has been equipped with resistive anode Micromegas (MM) or Gas Electron Multiplier (GEM) modules. Both the MM and GEM technologies have been studied with an electron beam up to 6 GeV in a 1 Tesla solenoid magnet. After introducing the current R&D status, recent results will be presented including field distortions, ion gating and spatial resolution as well as future plans of the LCTPC R&D.

Analog front-end design of the STS/MUCH-XYTER2—full size prototype ASIC for the CBM experiment

NASA Astrophysics Data System (ADS)

Kleczek, Rafal

2017-01-01

The design of the analog front-end of the STS/MUCH-XYTER2 ASIC, a full-size prototype chip for the Silicon Tracking System (STS, based on double-sided silicon strip sensors) and Muon Chamber (MUCH, based on gas sensors) detectors is presented. The ASIC contains 128 charge processing channels, each built of a charge sensitive amplifier, a polarity selection circuit and two pulse shaping amplifiers forming two parallel signal paths. The first path is used for timing measurement with a fast discriminator. The second path allows low-noise amplitude measurement with a 5-bit continuous-time flash ADC. Different operating conditions and constraints posed by two target detectors' applications require front-end electronics flexibility to meet extended system-wise requirements. The presented circuit implements switchable shaper peaking time, gain switching and trimming, input amplifier pulsed reset circuit, fail-safe measures. The power consumption is scalable (for the STS and the MUCH modes), but limited to 10 mW/channel.

Designing a Low-Cost Multifunctional Infant Incubator.

PubMed

Tran, Kevin; Gibson, Aaron; Wong, Don; Tilahun, Dagmawi; Selock, Nicholas; Good, Theresa; Ram, Geetha; Tolosa, Leah; Tolosa, Michael; Kostov, Yordan; Woo, Hyung Chul; Frizzell, Michael; Fulda, Victor; Gopinath, Ramya; Prasad, J Shashidhara; Sudarshan, Hanumappa; Venkatesan, Arunkumar; Kumar, V Sashi; Shylaja, N; Rao, Govind

2014-06-01

Every year, an unacceptably large number of infant deaths occur in developing nations, with premature birth and asphyxia being two of the leading causes. A well-regulated thermal environment is critical for neonatal survival. Advanced incubators currently exist, but they are far too expensive to meet the needs of developing nations. We are developing a thermodynamically advanced low-cost incubator suitable for operation in a low-resource environment. Our design features three innovations: (1) a disposable baby chamber to reduce infant mortality due to nosocomial infections, (2) a passive cooling mechanism using low-cost heat pipes and evaporative cooling from locally found clay pots, and (3) insulated panels and a thermal bank consisting of water that effectively preserve and store heat. We developed a prototype incubator and visited and presented our design to our partnership hospital site in Mysore, India. After obtaining feedback, we have determined realistic, nontrivial design requirements and constraints in order to develop a new prototype incubator for clinical trials in hospitals in India. © 2014 Society for Laboratory Automation and Screening.

MICROROC: MICRO-mesh gaseous structure Read-Out Chip

NASA Astrophysics Data System (ADS)

Adloff, C.; Blaha, J.; Chefdeville, M.; Dalmaz, A.; Drancourt, C.; Dulucq, F.; Espargilière, A.; Gaglione, R.; Geffroy, N.; Jacquemier, J.; Karyotakis, Y.; Martin-Chassard, G.; Prast, J.; Seguin-Moreau, N.; de La Taille, Ch; Vouters, G.

2012-01-01

MICRO MEsh GAseous Structure (MICROMEGAS) and Gas Electron Multipliers (GEM) detectors are two candidates for the active medium of a Digital Hadronic CALorimeter (DHCAL) as part of a high energy physics experiment at a future linear collider (ILC/CLIC). Physics requirements lead to a highly granular hadronic calorimeter with up to thirty million channels with probably only hit information (digital readout calorimeter). To validate the concept of digital hadronic calorimetry with such small cell size, the construction and test of a cubic meter technological prototype, made of 40 planes of one square meter each, is necessary. This technological prototype would contain about 400 000 electronic channels, thus requiring the development of front-end ASIC. Based on the experience gained with previous ASIC that were mounted on detectors and tested in particle beams, a new ASIC called MICROROC has been developped. This paper summarizes the caracterisation campaign that was conducted on this new chip as well as its integration into a large area Micromegas chamber of one square meter.

Evaluating probabilistic dengue risk forecasts from a prototype early warning system for Brazil.

PubMed

Lowe, Rachel; Coelho, Caio As; Barcellos, Christovam; Carvalho, Marilia Sá; Catão, Rafael De Castro; Coelho, Giovanini E; Ramalho, Walter Massa; Bailey, Trevor C; Stephenson, David B; Rodó, Xavier

2016-02-24

Recently, a prototype dengue early warning system was developed to produce probabilistic forecasts of dengue risk three months ahead of the 2014 World Cup in Brazil. Here, we evaluate the categorical dengue forecasts across all microregions in Brazil, using dengue cases reported in June 2014 to validate the model. We also compare the forecast model framework to a null model, based on seasonal averages of previously observed dengue incidence. When considering the ability of the two models to predict high dengue risk across Brazil, the forecast model produced more hits and fewer missed events than the null model, with a hit rate of 57% for the forecast model compared to 33% for the null model. This early warning model framework may be useful to public health services, not only ahead of mass gatherings, but also before the peak dengue season each year, to control potentially explosive dengue epidemics.

Development of a novel digestion chamber for human and porcine islet isolation.

PubMed

Gray, D W R; Sudhakaran, N; Titus, T T; McShane, P; Johnson, P

2004-05-01

The current technique of human pancreas digestion for islet isolation relies on selective distribution of collagenase delivered via the pancreatic duct to produce digestion and removal of peri-acinar fibrous tissue. However, the collagenase has relatively little effect on the interlobular fibrous tissue, which must therefore be broken down by mechanical means within the digestion chamber so as to release the contained acini and islets. The current way of achieving this in the Ricordi chamber is to place five or six stainless steel balls within the chamber and shake vigorously. The shaking presumably breaks down the interlobular fibrous tissue by a combination of shear force induced by the movement of tissue through the shaking process, assisted by numerous blows from the steel balls. Intuitively, one would expect some islets would be destroyed rather than released by such a battering. In an attempt to improve the efficiency of islet isolation we have designed a new digestion/filtration chamber that consists of a glass cylinder, sealed with Teflon plates holding in mesh filters at each end, secured in place by a central threaded tie-rod and external knurled nuts. A ring-shaped piston within the cylinder can be pushed up and down the travel by two rods passing out through sealed ports in the Teflon disk at one end and connected to an external handle. The handle is used to gently push the piston up and down the travel of the cylinder, which pushes the fluid and tissue through the central lumen of the ring-piston. A series of hooks attached to the central tie-rod catch the fibrous strands of the passing tissue; the shearing forces produced cause disruption by a process thought to be similar to teasing the tissue apart with fine forceps. A series of initial experiments with human pancreas showed the prototype to be too large, causing temperature control problems, and a redesigned smaller chamber was produced, maintaining the crucial design features. Experience processing five human pancreata has now demonstrated that in three of five pancreata the new chamber produced a good yield (>200,000 I.E.) of remarkably well separated and intact islets, the entire dispersion process being under 1 hour. However, in two isolations the collagenase digestion was poor, with few free islets. A copy of the new chamber (reserved for porcine work only) has been produced, as well as a copy of the Ricordi chamber. We have confirmed that the new chamber can isolate porcine islets in large numbers (>5000 islets/g pancreas [n = 2], but note that pig islets are small). These preliminary studies are sufficiently encouraging to justify further direct comparison with the Ricordi chamber for the purpose of animal and human islet isolation.

Sex and the Self: The Impact of Early Sexual Onset on the Self-Concept and Subsequent Risky Behavior of African American Adolescents

ERIC Educational Resources Information Center

Houlihan, Amy E.; Gibbons, Frederick X.; Gerrard, Meg; Yeh, Hsiu-Chen; Reimer, Rachel A.; Murry, Velma M.

2008-01-01

A 5-year longitudinal study of African American adolescents, aged 10 to 12 at Time 1, used the prototype/willingness (prototype) model to examine the (social) cognitive effects of the onset of sexual behavior on self-concept. Structural equation modeling (SEM) showed that becoming sexually active was related to favorable changes in adolescents'…

Development and functionality of a handheld computer program to improve fruit and vegetable intake among low-income youth

PubMed Central

Nollen, Nicole L.; Hutcheson, Tresza; Carlson, Susan; Rapoff, Michael; Goggin, Kathy; Mayfield, Carlene; Ellerbeck, Edward

2013-01-01

Mobile technologies hold promise for improving diet and physical activity, but little attention is given to creating programs that adolescents like and will use. This study developed a personal digital assistant (PDA) program to promote increased intake of fruits and vegetables (FV) in predominately low-income, ethnic minority girls. This study used a three-phase community-engaged process, including (i) engagement of a Student Advisory Board (SAB) to determine comfort with PDAs; (ii) early testing of Prototype I and rapid re-design by the SAB and (iii) feasibility testing of Prototype II in a new sample of girls. Phase 1 results showed that girls were comfortable with the PDA. Testing of Prototype I in Phase 2 showed that acceptability was mixed, with girls responding to 47.3% of the prompts. Girls wanted more reminders, accountability in monitoring FV, help in meeting daily goals and free music downloads based on program use. The PDA was reprogrammed and testing of Prototype II in Phase 3 demonstrated marked improvement in use (78.3%), increases in FV intake (1.8 ± 2.6 daily servings) and good overall satisfaction. Findings suggest that mobile technology designed with the early input of youth is a promising way to improve adolescent health behaviors. PMID:22949499

Early warning system for aftershocks

USGS Publications Warehouse

Bakun, W.H.; Fischer, F.G.; Jensen, E.G.; VanSchaack, J.

1994-01-01

A prototype early warning system to provide San Francisco and Oakland, California a few tens-of-seconds warning of incoming strong ground shaking from already-occurred M ≧ 3.7 aftershocks of the magnitude 7.1 17 October 1989 Loma Prieta earthquake was operational on 28 October 1989. The prototype system consisted of four components: ground motion sensors in the epicentral area, a central receiver, a radio repeater, and radio receivers. One of the radio receivers was deployed at the California Department of Transportation (CALTRANS) headquarters at the damaged Cypress Street section of the I-880 freeway in Oakland, California on 28 October 1989 and provided about 20 sec of warning before shaking from the M 4.5 Loma Prieta aftershock that occurred on 2 November 1989 at 0550 UTC. In its first 6 months of operation, the system generated triggers for all 12 M > 3.7 aftershocks for which trigger documentation is preserved, did not trigger on any M ≦ 3.6 aftershocks, and produced one false trigger as a result of a now-corrected single point of failure design flaw. Because the prototype system demonstrated that potentially useful warnings of strong shaking from aftershocks are feasible, the USGS has completed a portable early warning system for aftershocks that can be deployed anywhere.

Myocardial Tbx20 regulates early atrioventricular canal formation and endocardial epithelial-mesenchymal transition via Bmp2

PubMed Central

Cai, Xiaoqiang; Nomura-Kitabayashi, Aya; Cai, Weibin; Yan, Jianyun; Christoffels, Vincent M.; Cai, Chen-Leng

2011-01-01

During early embryogenesis, the formation of the cardiac atrioventricular canal (AVC) facilitates the transition of the heart from a linear tube into a chambered organ. However, the genetic pathways underlying this developmental process are poorly understood. The T-box transcription factor Tbx20 is expressed predominantly in the AVC of early heart tube. It was shown that Tbx20 activates Nmyc1 and suppresses Tbx2 expression to promote proliferation and specification of the atrial and ventricular chambers, yet it is not known if Tbx20 is involved in early AVC development. Here, we report that mice lacking Tbx20 in the AVC myocardium fail to form the AVC constriction, and the endocardial epithelial-mesenchymal transition (EMT) is severely perturbed. Tbx20 maintains expression of a variety of genes, including Bmp2, Tbx3 and Hand1 in the AVC myocardium. Intriguingly, we found Bmp2 downstream genes involved in the EMT initiation are also downregulated. In addition, re-expression of Bmp2 in the AVC myocardium substantially rescues the EMT defects resulting from the lack of Tbx20, suggesting Bmp2 is one of the key downstream targets of Tbx20 in AVC development. Our data support a complex signaling network with Tbx20 suppressing Tbx2 in the AVC myocardium but also indirectly promoting Tbx2 expression through Bmp2. The spatiotemporal expression of Tbx2 in the AVC appears to be balanced between these two opposing signals. Overall, our study provides genetic evidence that Tbx20 has essential roles in regulating AVC development that coordinate early cardiac chamber formation. PMID:21983003

Myocardial Tbx20 regulates early atrioventricular canal formation and endocardial epithelial-mesenchymal transition via Bmp2.

PubMed

Cai, Xiaoqiang; Nomura-Kitabayashi, Aya; Cai, Weibin; Yan, Jianyun; Christoffels, Vincent M; Cai, Chen-Leng

2011-12-15

During early embryogenesis, the formation of the cardiac atrioventricular canal (AVC) facilitates the transition of the heart from a linear tube into a chambered organ. However, the genetic pathways underlying this developmental process are poorly understood. The T-box transcription factor Tbx20 is expressed predominantly in the AVC of early heart tube. It was shown that Tbx20 activates Nmyc1 and suppresses Tbx2 expression to promote proliferation and specification of the atrial and ventricular chambers, yet it is not known if Tbx20 is involved in early AVC development. Here, we report that mice lacking Tbx20 in the AVC myocardium fail to form the AVC constriction, and the endocardial epithelial-mesenchymal transition (EMT) is severely perturbed. Tbx20 maintains expression of a variety of genes, including Bmp2, Tbx3 and Hand1 in the AVC myocardium. Intriguingly, we found Bmp2 downstream genes involved in the EMT initiation are also downregulated. In addition, re-expression of Bmp2 in the AVC myocardium substantially rescues the EMT defects resulting from the lack of Tbx20, suggesting Bmp2 is one of the key downstream targets of Tbx20 in AVC development. Our data support a complex signaling network with Tbx20 suppressing Tbx2 in the AVC myocardium but also indirectly promoting Tbx2 expression through Bmp2. The spatiotemporal expression of Tbx2 in the AVC appears to be balanced between these two opposing signals. Overall, our study provides genetic evidence that Tbx20 has essential roles in regulating AVC development that coordinate early cardiac chamber formation. Copyright © 2011 Elsevier Inc. All rights reserved.

Recent Infrasound Calibration Activity at Los Alamos

NASA Astrophysics Data System (ADS)

Whitaker, R. W.; Marcillo, O. E.

2014-12-01

Absolute infrasound sensor calibration is necessary for estimating source sizes from measured waveforms. This can be an important function in treaty monitoring. The Los Alamos infrasound calibration chamber is capable of absolute calibration. Early in 2014 the Los Alamos infrasound calibration chamber resumed operations in its new location after an unplanned move two years earlier. The chamber has two sources of calibration signals. The first is the original mechanical piston, and the second is a CLD Dynamics Model 316 electro-mechanical unit that can be digitally controlled and provide a richer set of calibration options. During 2008-2010 a number of upgrades were incorporated for improved operation and recording. In this poster we give an overview of recent chamber work on sensor calibrations, calibration with the CLD unit, some measurements with different porous hoses and work with impulse sources.

SU-E-T-571: Newly Emerging Integrated Transmission Detector Systems Provide Online Quality Assurance of External Beam Radiation Therapy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hoffman, D; Chung, E; Hess, C

2015-06-15

Purpose: Two newly emerging transmission detectors positioned upstream from the patient have been evaluated for online quality assurance of external beam radiotherapy. The prototype for the Integral Quality Monitor (IQM), developed by iRT Systems GmbH (Koblenz, Germany) is a large-area ion chamber mounted on the linac accessory tray to monitor photon fluence, energy, beam shape, and gantry position during treatment. The ion chamber utilizes a thickness gradient which records variable response dependent on beam position. The prototype of Delta4 Discover™, developed by ScandiDos (Uppsala, Sweden) is a linac accessory tray mounted 4040 diode array that measures photon fluence during patientmore » treatment. Both systems are employable for patient specific QA prior to treatment delivery. Methods: Our institution evaluated the reproducibility of measurements using various beam types, including VMAT treatment plans with both the IQM ion chamber and the Delta4 Discover diode array. Additionally, the IQM’s effect on photon fluence, dose response, simulated beam error detection, and the accuracy of the integrated barometer, thermometer, and inclinometer were characterized. The evaluated photon beam errors are based on the annual tolerances specified in AAPM TG-142. Results: Repeated VMAT treatments were measured with 0.16% reproducibility by the IQM and 0.55% reproducibility by the Delta4 Discover. The IQM attenuated 6, 10, and 15 MV photon beams by 5.43±0.02%, 4.60±0.02%, and 4.21±0.03% respectively. Photon beam profiles were affected <1.5% in the non-penumbra regions. The IQM’s ion chamber’s dose response was linear and the thermometer, barometer, and inclinometer agreed with other calibrated devices. The device detected variations in monitor units delivered (1%), field position (3mm), single MLC leaf positions (13mm), and photon energy. Conclusion: We have characterized two new transmissions detector systems designed to provide in-vivo like measurements upstream from the patient. Both systems demonstrate substantial utility for online treatment verification and QA of photon external beam radiotherapy.« less

Seamless transitions from early prototypes to mature operational software - A technology that enables the process for planning and scheduling applications

NASA Technical Reports Server (NTRS)

Hornstein, Rhoda S.; Wunderlich, Dana A.; Willoughby, John K.

1992-01-01

New and innovative software technology is presented that provides a cost effective bridge for smoothly transitioning prototype software, in the field of planning and scheduling, into an operational environment. Specifically, this technology mixes the flexibility and human design efficiency of dynamic data typing with the rigor and run-time efficiencies of static data typing. This new technology provides a very valuable tool for conducting the extensive, up-front system prototyping that leads to specifying the correct system and producing a reliable, efficient version that will be operationally effective and will be accepted by the intended users.

Superstrong Adjustable Permanent Magnet for a Linear Collider Final Focus

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mihara, T.

A superstrong permanent magnet quadrupole (PMQ) is one of the candidates for the final focus lens for the linear collider because of its compactness and low power consumption. The first fabricated prototype of our PMQ achieved a 300T/m superstrong field gradient with a 100mm overall magnet radius and a 7mm bore radius, but a drawback is its fixed strength. Therefore, a second prototype of PMQ, whose strength is adjustable, was fabricated. Its strength adjustability is based on the ''double ring structure'', rotating subdivided magnet slices separately. This second prototype is being tested. Some of the early results are presented.

Exhaust Plume Measurements of the VASIMR VX-200

NASA Astrophysics Data System (ADS)

Longmier, Benjamin; Bering, Edgar, III; Squire, Jared; Glover, Tim; Chang-Diaz, Franklin; Brukardt, Michael

2008-11-01

Recent progress is discussed in the development of an advanced RF electric propulsion concept: the Variable Specific Impulse Magnetoplasma Rocket (VASIMR) VX-200 engine, a 200 kW flight-technology prototype. Results from high power Helicon only and Helicon with ICRH experiments are performed on the VX-200 using argon plasma. Recent measurements of axial plasma density and potential profiles, magnetic field-line shaping, charge exchange, and force measurements taken in the plume of the VX-200 exhaust are made within a new 125 cubic meter cryo-pumped vacuum chamber and are presented in the context of RF plasma thruster physics.

Polymer-based microfluidic chips for isothermal amplification of nucleic acids

NASA Astrophysics Data System (ADS)

Posmitnaya, Y. S.; Rudnitskaya, G. E.; Tupik, A. N.; Lukashenko, T. A.; Bukatin, A. C.; Evstrapov, A. A.

2017-11-01

Creation of low-cost compact devices based on microfluidic platforms for biological and medical research depends on the degree of development and enhancement of prototyping technologies. Two designs of polymer and hybrid microfluidic devices fabricated by soft lithography and intended for isothermal amplification and polymerase chain reaction are presented in this paper. The digital helicase-dependent isothermal amplification was tested in the device containing a droplet generator. Polymerase chain reaction was carried out in the hybrid microfluidic device having ten reaction chambers. A synthesized cDNA fragment of GAPDH housekeeping gene was used as a target.

Front-end electronics for the LZ experiment

NASA Astrophysics Data System (ADS)

Morad, James; LZ Collaboration

2016-03-01

LZ is a second generation direct dark matter detection experiment with 5.6 tonnes of liquid xenon active target, which will be instrumented as a two-phase time projection chamber (TPC). The peripheral xenon outside the active TPC (``skin'') will also be instrumented. In addition, there will be a liquid scintillator based outer veto surrounding the main cryostat. All of these systems will be read out using photomultiplier tubes. I will present the designs for front-end electronics for all these systems, which have been optimized for shaping times, gains, and low noise. Preliminary results from prototype boards will also be presented.

Instrumentation development for the EUVE. [Extreme Ultraviolet Explorer Satellite

NASA Technical Reports Server (NTRS)

Finley, D.

1980-01-01

The prototype mirror was successfully replated with a thick layer of nickel and diamond turned again. Optimization of the sensitivity of the instruments was studied with emphasis on the filter material, and on the available telemetry. The JHU Preliminary Project Definition Document was critically analyzed. Further studies of the electron cloud distribution produced by a channel plate were performed, and a wedge and strip anode with 17 quartets per inch was shown to image with better than 0.5% linearity. Half the microchannel plates being used in the lifetest completed initial processing and are in the lifetest vacuum chamber.

Testing of materials for passive thermal control of space suits

NASA Technical Reports Server (NTRS)

Squire, Bernadette

1988-01-01

An effort is underway to determine the coating material of choice for the AX-5 prototype hard space suit. Samples of 6061 aluminum have been coated with one of 10 selected metal coatings, and subjected to corrosion, abrasion, and thermal testing. Changes in reflectance after exposure are documented. Plated gold exhibited minimal degradation of optical properties. A computer model is used in evaluating coating thermal performance in the EVA environment. The model is verified with an experiment designed to measure the heat transfer characteristics of coated space suit parts in a thermal vacuum chamber. Details of this experiment are presented.

Construction and performance of the sTGC and MicroMegas chambers for ATLAS NSW upgrade

NASA Astrophysics Data System (ADS)

Sekhniaidze, G.

2017-03-01

The innermost stations of the current ATLAS muon end-cap system, the Small Wheels, must be upgraded in 2019 to retain their good precision tracking and trigger capabilities in the high background environment expected with the upcoming luminosity increase of the LHC. The New Small Wheels (NSW) will employ two chamber technologies: eight layers of MicroMegas (MM) arranged in two quadruplets, sandwiched between two quadruplets of small-strip Thin Gap Chambers (sTGC) for a total of about 2400 m2 of detection planes. All quadruplets have trapezoidal shapes with surface areas between 1 and 3 m2. Both MM and sTGC systems will independently provide trigger and tracking capabilities. The readout boards are industrially produced for both technologies and an accurate quality control is needed. In order to achieve a 15% transverse momentum resolution for 1 TeV muons, in addition to an excellent intrinsic resolution (010 μm), the mechanical precision of each plane of the assembled modules must be as good as 30 μm along the precision coordinate and 80 μm perpendicular to the chamber. In 2016 the milestone to build the first module-0 prototypes for both technologies has been reached. The construction procedure of the module-0 detectors will be reviewed, along with the results of the quality control checks performed during construction. The module-0 have been measured and subjected to a thorough validation. Results obtained with high-energy particle beams, with cosmic rays and with X-rays will be presented.

Performance of the CELSS Antarctic Analog Project (CAAP) crop production system.

PubMed

Bubenheim, D L; Schlick, G; Wilson, D; Bates, M

2003-01-01

Regenerative life support systems potentially offer a level of self-sufficiency and a decrease in logistics and associated costs in support of space exploration and habitation missions. Current state-of-the-art in plant-based, regenerative life support requires resources in excess of allocation proposed for candidate mission scenarios. Feasibility thresholds have been identified for candidate exploration missions. The goal of this paper is to review recent advances in performance achieved in the CELSS Antarctic Analog Project (CAAP) in light of the likely resource constraints. A prototype CAAP crop production chamber has been constructed and operated at the Ames Research Center. The chamber includes a number of unique hardware and software components focused on attempts to increase production efficiency, increase energy efficiency, and control the flow of energy and mass through the system. Both single crop, batch production and continuous cultivation of mixed crops production studies have been completed. The crop productivity as well as engineering performance of the chamber are described. For each scenario, energy required and partitioned for lighting, cooling, pumping, fans, etc. is quantified. Crop production and the resulting lighting efficiency and energy conversion efficiencies are presented. In the mixed-crop scenario, with 27 different crops under cultivation, 17 m2 of crop area provided a mean of 515 g edible biomass per day (85% of the approximate 620 g required for one person). Enhanced engineering and crop production performance achieved with the CAAP chamber, compared with current state-of-the-art, places plant-based life support systems at the threshold of feasibility. c2002 Published by Elsevier Science Ltd on behalf of COSPAR.

Performance of the CELSS Antarctic Analog Project (CAAP) crop production system

NASA Astrophysics Data System (ADS)

Bubenheim, D. L.; Schlick, G.; Wilson, D.; Bates, M.

Regenerative life support systems potentially offer a level of self-sufficiency and a decrease in logistics and associated costs in support of space exploration and habitation missions. Current state-of-the-art in plant-based, regenerative life support requires resources in excess of allocation proposed for candidate mission scenarios. Feasibility thresholds have been identified for candidate exploration missions. The goal of this paper is to review recent advances in performance achieved in the CELSS Antarctic Analog Project (CAAP) in light of the likely resource constraints. A prototype CAAP crop production chamber has been constructed and operated at the Ames Research Center. The chamber includes a number of unique hardware and software components focused on attempts to increase production efficiency, increase energy efficiency, and control the flow of energy and mass through the system. Both single crop, batch production and continuous cultivation of mixed crops production studies have been completed. The crop productivity as well as engineering performance of the chamber are described. For each scenario, energy required and partitioned for lighting, cooling, pumping, fans, etc. is quantified. Crop production and the resulting lighting efficiency and energy conversion efficiencies are presented. In the mixed-crop scenario, with 27 different crops under cultivation, 17 m2 of crop area provided a mean of 515g edible biomass per day (85% of the approximate 620 g required for one person). Enhanced engineering and crop production performance achieved with the CAAP chamber, compared with current state-of-the-art, places plant-based life support systems at the threshold of feasibility.

Design of Refractory Metal Heat Pipe Life Test Environment Chamber, Cooling System, and Radio Frequency Heating System

NASA Technical Reports Server (NTRS)

Martin, J. J.; Bragg-Sitton, S. M.; Reid, R. S.; Stewart, E. T.; Davis, J. D.

2011-01-01

A series of 16 Mo-44.5%Re alloy/sodium heat pipes will be experimentally tested to examine heat pipe aging. To support this evaluation, an environmental test chamber and a number of auxiliary subsystems are required. These subsystems include radio frequency (RF) power supplies/inductive coils, recirculation water coolant loops, and chamber gas conditioning. The heat pipes will be grouped, based on like power and gas mixture requirements, into three clusters of five units each, configured in a pentagonal arrangement. The highest powered heat pipe will be tested separately. Test chamber atmospheric purity is targeted at <0.3 ppb oxygen at an approximate operating pressure of 76 torr (.1.5 psia), maintained by active purification (oxygen level is comparable to a 10(exp -6) torr environment). Treated water will be used in two independent cooling circuits to remove .85 kW. One circuit will service the RF hardware while the other will maintain the heat pipe calorimetry. Initial procedures for the startup and operation of support systems have been identified. Each of these subsystems is outfitted with a variety of instrumentation, integrated with distributed real-time controllers and computers. A local area network provides communication between all devices. This data and control network continuously monitors the health of the test hardware, providing warning indicators followed by automatic shutdown should potentially damaging conditions develop. During hardware construction, a number of checkout tests.many making use of stainless steel prototype heat pipes that are already fabricated.will be required to verify operation.

Performance of the CELSS Antarctic Analog Project (CAAP) crop production system

NASA Technical Reports Server (NTRS)

Bubenheim, D. L.; Schlick, G.; Wilson, D.; Bates, M.

2003-01-01

Regenerative life support systems potentially offer a level of self-sufficiency and a decrease in logistics and associated costs in support of space exploration and habitation missions. Current state-of-the-art in plant-based, regenerative life support requires resources in excess of allocation proposed for candidate mission scenarios. Feasibility thresholds have been identified for candidate exploration missions. The goal of this paper is to review recent advances in performance achieved in the CELSS Antarctic Analog Project (CAAP) in light of the likely resource constraints. A prototype CAAP crop production chamber has been constructed and operated at the Ames Research Center. The chamber includes a number of unique hardware and software components focused on attempts to increase production efficiency, increase energy efficiency, and control the flow of energy and mass through the system. Both single crop, batch production and continuous cultivation of mixed crops production studies have been completed. The crop productivity as well as engineering performance of the chamber are described. For each scenario, energy required and partitioned for lighting, cooling, pumping, fans, etc. is quantified. Crop production and the resulting lighting efficiency and energy conversion efficiencies are presented. In the mixed-crop scenario, with 27 different crops under cultivation, 17 m2 of crop area provided a mean of 515 g edible biomass per day (85% of the approximate 620 g required for one person). Enhanced engineering and crop production performance achieved with the CAAP chamber, compared with current state-of-the-art, places plant-based life support systems at the threshold of feasibility. c2002 Published by Elsevier Science Ltd on behalf of COSPAR.

SU-D-19A-01: Can Farmer-Type Ionization Chambers Be Used to Improve the Accuracy of Low-Energy Electron Beam Reference Dosimetry?

DOE Office of Scientific and Technical Information (OSTI.GOV)

Muir, B R; McEwen, M R

2014-06-01

Purpose: To investigate the use of cylindrical Farmer-type ionization chambers to improve the accuracy of low-energy electron beam calibration. Historically, these chamber types have not been used in beams with incident energies less than 10 MeV (R{sub 5} {sub 0} < 4.3 cm) because early investigations suggested large (up to 5 %) fluence perturbation factors in these beams, implying that a significant component of uncertainty would be introduced if used for calibration. More recently, the assumptions used to determine perturbation corrections for cylindrical chambers have been questioned. Methods: Measurements are made with cylindrical chambers in Elekta Precise 4, 8 andmore » 18 MeV electron beams. Several chamber types are investigated that employ graphite walls and aluminum electrodes with very similar specifications (NE2571, NE2505/3, FC65-G). Depth-ionization scans are measured in water in the 8 and 18 MeV beams. To reduce uncertainty from chamber positioning, measurements in the 4 MeV beam are made at the reference depth in Virtual Water™. The variability of perturbation factors is quantified by comparing normalized response of various chambers. Results: Normalized ion chamber response varies by less than 0.7 % for similar chambers at average electron energies corresponding to that at the reference depth from 4 or 6 MeV beams. Similarly, normalized measurements made with similar chambers at the reference depth in the 4 MeV beam vary by less than 0.4 %. Absorbed dose calibration coefficients derived from these results are stable within 0.1 % on average over a period of 6 years. Conclusion: These results indicate that the uncertainty associated with differences in fluence perturbations for cylindrical chambers with similar specifications is only 0.2 %. The excellent long-term stability of these chambers in both photon and electron beams suggests that these chambers might offer the best performance for all reference dosimetry applications.« less

Surveyor Atlas-Centaur Shroud Venting Structural Test in the Space Power Chambers

NASA Image and Video Library

1967-06-21

Setup of a Surveyor/Atlas/Centaur shroud in the Space Power Chambers for a leak test at the National Aeronautics and Space Administration (NASA) Lewis Research Center. Centaur was a 15,000-pound thrust second-stage rocket designed for the military in 1957 and 1958 by General Dynamics. It was the first major rocket to use the liquid hydrogen technology developed by Lewis in the 1950s. The Centaur Program suffered numerous problems before being transferred to Lewis in 1962. Several test facilities at Lewis’ main campus and Plum Brook Station were built or modified specifically for Centaur, including the Space Power Chambers. In 1961, NASA Lewis management decided to convert its Altitude Wind Tunnel into two large test chambers and later renamed it the Space Power Chambers. The conversion, which took over 2 years, included the removal of the tunnel’s internal components and insertion of bulkheads to seal off the new chambers. The larger chamber, seen here, could simulate altitudes of 100,000 feet. It was used for Centaur shroud separation and propellant management studies until the early 1970s. The leak test in this photograph was likely an attempt to verify that the shroud’s honeycomb shell did not seep any of its internal air when the chamber was evacuated to pressures similar to those found in the upper atmosphere.

Motor-Life-Skills of Toddlers--A Comparative Study of Norwegian and British Boys and Girls Applying the Early Years Movement Skills Checklist

ERIC Educational Resources Information Center

Moser, Thomas; Reikerås, Elin

2016-01-01

This article discusses motor-life-skills in a sample (n?=?1083) of 33 months (2.9-year-old) children in Norwegian early childhood education and care institutions (ECEC-institutions) and to compare the findings with the results from a similar British sample. The Early Years Movement Skills Checklist (EYMSC) (Chambers and Sugden 2006) was applied.…

Full-Scale Hollow Fiber Spacesuit Water Membrane Evaporator Prototype Development and Testing for Advanced Spacesuits

NASA Technical Reports Server (NTRS)

Bue, Grant; Trevino, Luis; Tsioulos, Gus; Mitchell, Keith; Dillon, Paul; Weaver, Gregg

2009-01-01

The spacesuit water membrane evaporator (SWME) is being developed to perform the thermal control function for advanced spacesuits to take advantage of recent advances in micropore membrane technology in providing a robust heat-rejection device that is potentially less sensitive to contamination than is the sublimator. Principles of a sheet membrane SWME design were demonstrated using a prototypic test article that was tested in a vacuum chamber at JSC in July 1999. The Membrana Celgard X50-215 microporous hollow fiber (HoFi) membrane was selected after recent contamination tests as the superior candidate among commercial alternatives for HoFi SWME prototype development. Although a number of design variants were considered, one that grouped the fiber layers into stacks, which were separated by small spaces and packaged into a cylindrical shape, was deemed best for further development. An analysis of test data showed that eight layer stacks of the HoFi sheets that had good exposure on each side of the stack would evaporate water with high efficiency. A design that has 15,000 tubes, with 18 cm of exposed tubes between headers has been built and tested that meets the size, weight, and performance requirements of the SWME. This full-scale prototype consists of 30 stacks, each of which are formed into a chevron shape and separated by spacers and organized into three sectors of ten nested stacks. Testing has been performed to show contamination resistance to the constituents expected to be found in potable water produced by the distillation processes. Other tests showed the sensitivity to surfactants.

Development of a 12-Thrust Chamber Kerosene /Oxygen Primary Rocket Sub-System for an Early (1964) Air-Augmented Rocket Ground-Test System

NASA Technical Reports Server (NTRS)

Pryor, D.; Hyde, E. H.; Escher, W. J. D.

1999-01-01

Airbreathing/Rocket combined-cycle, and specifically rocket-based combined- cycle (RBCC), propulsion systems, typically employ an internal engine flow-path installed primary rocket subsystem. To achieve acceptably short mixing lengths in effecting the "air augmentation" process, a large rocket-exhaust/air interfacial mixing surface is needed. This leads, in some engine design concepts, to a "cluster" of small rocket units, suitably arrayed in the flowpath. To support an early (1964) subscale ground-test of a specific RBCC concept, such a 12-rocket cluster was developed by NASA's Marshall Space Flight Center (MSFC). The small primary rockets used in the cluster assembly were modified versions of an existing small kerosene/oxygen water-cooled rocket engine unit routinely tested at MSFC. Following individual thrust-chamber tests and overall subsystem qualification testing, the cluster assembly was installed at the U. S. Air Force's Arnold Engineering Development Center (AEDC) for RBCC systems testing. (The results of the special air-augmented rocket testing are not covered here.) While this project was eventually successfully completed, a number of hardware integration problems were met, leading to catastrophic thrust chamber failures. The principal "lessons learned" in conducting this early primary rocket subsystem experimental effort are documented here as a basic knowledge-base contribution for the benefit of today's RBCC research and development community.

The Stranger within: Luxembourg's Early School System as a European Prototype of Nationally Legitimized International Blends (ca. 1794-1844)

ERIC Educational Resources Information Center

Thyssen, Geert

2013-01-01

This comparative analysis of Luxembourg's early school (law) system reveals the extent to which European school systems reflect "national-cultural idiosyncrasies" apart from "structural isomorphism". It first examines the legal soil into which the Luxembourg school system was implanted. Legislative pendular swings, reflecting…

The decline of venture capital investment in early-stage life sciences poses a challenge to continued innovation.

PubMed

Fleming, Jonathan J

2015-02-01

A key element required for translating new knowledge into effective therapies is early-stage venture capital that finances the work needed to identify a lead molecule or medical device prototype and to develop it to the proof-of-concept stage. This early investment is distinguished by great uncertainty over whether the molecule or prototype is safe and effective, the stability of the regulatory standards to which clinical trials are designed, and the likelihood that large follow-on investments for commercial development can be secured. Regulatory and reimbursement policies have a profound impact on the amount of capital and the types of life science projects that investors pursue. In this article I analyze several recent trends in early-stage venture capital funding, describe how these trends are influenced by regulatory and reimbursement policies, and discuss the role of policy makers in bringing new treatments to market. Policy makers can foster renewed private investment into critically needed early-stage products by increasing Small Business Innovation Research (SBIR) funding and public support for clinical trials in targeted areas of interest; creating regulatory pathways to enable early testing of experimental compounds in limited populations; and offering economic incentives for investors and developers in designated therapeutic areas. Project HOPE—The People-to-People Health Foundation, Inc.

The effects of sleep deprivation on dissociable prototype learning systems.

PubMed

Maddox, W Todd; Glass, Brian D; Zeithamova, Dagmar; Savarie, Zachary R; Bowen, Christopher; Matthews, Michael D; Schnyer, David M

2011-03-01

The cognitive neural underpinnings of prototype learning are becoming clear. Evidence points to 2 different neural systems, depending on the learning parameters. A/not-A (AN) prototype learning is mediated by posterior brain regions that are involved in early perceptual learning, whereas A/B (AB) is mediated by frontal and medial temporal lobe regions. To investigate the effects of sleep deprivation on AN and AB prototype learning and to use established prototype models to provide insights into the cognitive-processing locus of sleep-deprivation deficits. Participants performed an AN and an AB prototype learning task twice, separated by a 24-hour period, with or without sleep between testing sessions. Eighteen West Point cadets participated in the sleep-deprivation group, and 17 West Point cadets participated in a control group. Sleep deprivation led to an AN, but not an AB, performance deficit. Prototype model analyses indicated that the AN deficit was due to changes in attentional focus and a decrease in confidence that is reflected in an increased bias to respond non-A. The findings suggest that AN, but not AB, prototype learning is affected by sleep deprivation. Prototype model analyses support the notion that the effect of sleep deprivation on AN is consistent with lapses in attentional focus that are more detrimental to AN than to AB. This finding adds to a growing body of work that suggests that different performance changes associated with sleep deprivation can be attributed to a common mechanism of changes in simple attention and vigilance.

Rapid prototyping and stereolithography in dentistry

PubMed Central

Nayar, Sanjna; Bhuminathan, S.; Bhat, Wasim Manzoor

2015-01-01

The word rapid prototyping (RP) was first used in mechanical engineering field in the early 1980s to describe the act of producing a prototype, a unique product, the first product, or a reference model. In the past, prototypes were handmade by sculpting or casting, and their fabrication demanded a long time. Any and every prototype should undergo evaluation, correction of defects, and approval before the beginning of its mass or large scale production. Prototypes may also be used for specific or restricted purposes, in which case they are usually called a preseries model. With the development of information technology, three-dimensional models can be devised and built based on virtual prototypes. Computers can now be used to create accurately detailed projects that can be assessed from different perspectives in a process known as computer aided design (CAD). To materialize virtual objects using CAD, a computer aided manufacture (CAM) process has been developed. To transform a virtual file into a real object, CAM operates using a machine connected to a computer, similar to a printer or peripheral device. In 1987, Brix and Lambrecht used, for the first time, a prototype in health care. It was a three-dimensional model manufactured using a computer numerical control device, a type of machine that was the predecessor of RP. In 1991, human anatomy models produced with a technology called stereolithography were first used in a maxillofacial surgery clinic in Viena. PMID:26015715

Rapid prototyping and stereolithography in dentistry.

PubMed

Nayar, Sanjna; Bhuminathan, S; Bhat, Wasim Manzoor

2015-04-01

The word rapid prototyping (RP) was first used in mechanical engineering field in the early 1980s to describe the act of producing a prototype, a unique product, the first product, or a reference model. In the past, prototypes were handmade by sculpting or casting, and their fabrication demanded a long time. Any and every prototype should undergo evaluation, correction of defects, and approval before the beginning of its mass or large scale production. Prototypes may also be used for specific or restricted purposes, in which case they are usually called a preseries model. With the development of information technology, three-dimensional models can be devised and built based on virtual prototypes. Computers can now be used to create accurately detailed projects that can be assessed from different perspectives in a process known as computer aided design (CAD). To materialize virtual objects using CAD, a computer aided manufacture (CAM) process has been developed. To transform a virtual file into a real object, CAM operates using a machine connected to a computer, similar to a printer or peripheral device. In 1987, Brix and Lambrecht used, for the first time, a prototype in health care. It was a three-dimensional model manufactured using a computer numerical control device, a type of machine that was the predecessor of RP. In 1991, human anatomy models produced with a technology called stereolithography were first used in a maxillofacial surgery clinic in Viena.

Smart structure with elastomeric contact surface for prosthetic fingertip sensitivity development

NASA Astrophysics Data System (ADS)

Gu, Chunxin; Liu, Weiting; Yu, Ping; Cheng, Xiaoying; Fu, Xin

2017-09-01

Current flexible/compliant tactile sensors suffer from low sensitivity and high hysteresis introduced by the essential viscosity characteristic of soft material, either used as compliant sensing element or as flexible coverage. To overcome these disadvantages, this paper focuses on developing a tactile sensor with a smart hybrid structure to obtain comprehensive properties in terms of size, compliance, robustness and pressure sensing ability so as to meet the requirements of limited space applications such as prosthetic fingertips. Employing micro-fabricated tiny silicon-based pressure die as the sensing element, it is easy to have both small size and good mechanical performance. To protect it from potential damage and maintain the compliant surface, a rigid base and a soft layer form a sealed chamber and encapsulate the fixed die together with fluid. The fluid serves as highly efficient pressure propagation media of mechanical stimulus from the compliant skin to the pressure die without any hazard impacting the vulnerable connecting wires. To understand the pressure transmission mechanism, a simplified and concise analytic model of a spring system is proposed. Using easy fabrication technologies, a prototype of a 3 × 3 sensor array with total dimensions of 14 mm × 14 mm × 6.5 mm was developed. Based on the quasi-linear relationship between fluid volume and pressure, finite element modeling was developed to analyze the chamber deformation and pressure output of the sensor cell. Experimental tests of the sensor prototype were implemented. The results showed that the sensor cell had good sensing performance with sensitivity of 19.9 mV N-1, linearity of 0.998, repeatability error of 3.41%, and hysteresis error of 3.34%. The force sensing range was from 5 mN to 1.6 N.

Exploring School-Employer Partnerships to Expand Career Development and Early Work Experiences for Youth with Disabilities

ERIC Educational Resources Information Center

Carter, Erik W.; Trainor, Audrey A.; Cakiroglu, Orhan; Cole, Odessa; Swedeen, Beth; Ditchman, Nicole; Owens, Laura

2009-01-01

Although career development and early work experiences are associated with improved postschool employment outcomes for youth with disabilities, transition personnel report having few natural community partners to support and enhance these experiences. We surveyed 135 chambers of commerce and other employer networks to examine (a) whether and how…

Neural Network Classifies Teleoperation Data

NASA Technical Reports Server (NTRS)

Fiorini, Paolo; Giancaspro, Antonio; Losito, Sergio; Pasquariello, Guido

1994-01-01

Prototype artificial neural network, implemented in software, identifies phases of telemanipulator tasks in real time by analyzing feedback signals from force sensors on manipulator hand. Prototype is early, subsystem-level product of continuing effort to develop automated system that assists in training and supervising human control operator: provides symbolic feedback (e.g., warnings of impending collisions or evaluations of performance) to operator in real time during successive executions of same task. Also simplifies transition between teleoperation and autonomous modes of telerobotic system.

The Living Heart Project: A robust and integrative simulator for human heart function.

PubMed

Baillargeon, Brian; Rebelo, Nuno; Fox, David D; Taylor, Robert L; Kuhl, Ellen

2014-11-01

The heart is not only our most vital, but also our most complex organ: Precisely controlled by the interplay of electrical and mechanical fields, it consists of four chambers and four valves, which act in concert to regulate its filling, ejection, and overall pump function. While numerous computational models exist to study either the electrical or the mechanical response of its individual chambers, the integrative electro-mechanical response of the whole heart remains poorly understood. Here we present a proof-of-concept simulator for a four-chamber human heart model created from computer topography and magnetic resonance images. We illustrate the governing equations of excitation-contraction coupling and discretize them using a single, unified finite element environment. To illustrate the basic features of our model, we visualize the electrical potential and the mechanical deformation across the human heart throughout its cardiac cycle. To compare our simulation against common metrics of cardiac function, we extract the pressure-volume relationship and show that it agrees well with clinical observations. Our prototype model allows us to explore and understand the key features, physics, and technologies to create an integrative, predictive model of the living human heart. Ultimately, our simulator will open opportunities to probe landscapes of clinical parameters, and guide device design and treatment planning in cardiac diseases such as stenosis, regurgitation, or prolapse of the aortic, pulmonary, tricuspid, or mitral valve.

Status of the R&D activities for the upgrade of the ALICE TPC

NASA Astrophysics Data System (ADS)

Deisting, Alexander

2018-02-01

After the Long Shutdown 2 (LS2) the LHC will provide lead-lead collisions at interaction rates as high as 50 kHz. In order to cope with such conditions the ALICE Time Projection Chamber (TPC) needs to be upgraded. After the upgrade the TPC will run in a continuous mode, without any degradation of the momentum and dE/dx resolution compared to the performance of the present TPC. Since readout by multi-wire proportional chambers is no longer feasible with these requirements, new technologies have to be employed. In the new readout chambers the electron amplification is provided by a stack of four Gas ElectronMultiplier (GEM) foils. Here foils with a standard hole pitch of 140 μm as well as large pitch foils (280 μm) are used. Their high voltage settings and orientation have been optimised to provide an energy resolution of σE/E ≤ 12% at the photopeak of 55Fe. At the same settings the Ion BackFlow into the drift volume is less than 1% of the effective number of ions produced during gas amplification and the primary ionisations. This is necessary to prevent the accumulation of space charge, which eventually will distort the field in the drift volume. To ensure stable operation at the high loads during LHC run 3 the chambers have to be robust against discharges, too. With the selected configuration in a quadruple GEMstack the discharge probability is kept at the level of 10-12 discharges per incoming hadron. An overview of the ALICE TPC upgrade activities will be given in these proceedings and the optimised settings foreseen for the GEM stacks of the future readout chambers are introduced. Furthermore the outcome of two beam time campaigns at SPS and PS (at CERN) in the end of 2014 is shown. At this campaigns the stability against discharges and the dE/dx performance of a full size readout chamber prototype was tested. In addition it is reported on charging-up studies of 4GEM stacks and on tests of electromagnetic sagging of large GEM foils.

A Prototype Combination TPC Cherenkov Detector with GEM Readout for Tracking and Particle Identification and its Potential Use at an Electron Ion Collider

NASA Astrophysics Data System (ADS)

Woody, Craig; Azmoun, Babak; Majka, Richard; Phipps, Michael; Purschke, Martin; Smirnov, Nikolai

2018-02-01

A prototype detector is being developed which combines the functions of a Time Projection Chamber for charged particle tracking and a Cherenkov detector for particle identification. The TPC consists of a 10×10×10 cm3 drift volume where the charge is drifted to a 10×10 cm2 triple GEM detector. The charge is measured on a readout plane consisting of 2×10 mm2 chevron pads which provide a spatial resolution ˜ 100 μm per point in the chevron direction along with dE/dx information. The Cherenkov portion of the detector consists of a second 10×10 cm2 triple GEM with a photosensitive CsI photocathode on the top layer. This detector measures Cherenkov light produced in the drift gas of the TPC by high velocity particles which are above threshold. CF4 or CF4 mixtures will be used as the drift gas which are highly transparent to UV light and can provide excellent efficiency for detecting Cherenkov photons. The drift gas is also used as the operating gas for both GEM detectors. The prototype detector has been constructed and is currently being tested in the lab with sources and cosmic rays, and additional tests are planned in the future to study the detector in a test beam.

Assessment of an approach to printed polymer lenses

NASA Astrophysics Data System (ADS)

Marasco, Peter L.; Foote, Bob

2017-05-01

Additive manufacturing is proving its relevancy across a wide spectrum of development, prototyping and manufacturing in the US. However, there is a desire to move the capability beyond modeling and structural components. The use of additive manufacturing techniques to fabricate low-cost optics and optical systems is highly desirable in a number of markets. But processes and techniques for successfully printing an optic are currently very new. This paper discusses early advances in printing optics suitable for commercial and military applications. Data from and analysis of early prototype lenses fabricated using one possible technique will be included and discussed. The potential for additive manufacturing of optics to open the design space for complex optics and reduce development time, lowering cost and speeding up time to market, will also be discussed.

Evaluating probabilistic dengue risk forecasts from a prototype early warning system for Brazil

PubMed Central

Lowe, Rachel; Coelho, Caio AS; Barcellos, Christovam; Carvalho, Marilia Sá; Catão, Rafael De Castro; Coelho, Giovanini E; Ramalho, Walter Massa; Bailey, Trevor C; Stephenson, David B; Rodó, Xavier

2016-01-01

Recently, a prototype dengue early warning system was developed to produce probabilistic forecasts of dengue risk three months ahead of the 2014 World Cup in Brazil. Here, we evaluate the categorical dengue forecasts across all microregions in Brazil, using dengue cases reported in June 2014 to validate the model. We also compare the forecast model framework to a null model, based on seasonal averages of previously observed dengue incidence. When considering the ability of the two models to predict high dengue risk across Brazil, the forecast model produced more hits and fewer missed events than the null model, with a hit rate of 57% for the forecast model compared to 33% for the null model. This early warning model framework may be useful to public health services, not only ahead of mass gatherings, but also before the peak dengue season each year, to control potentially explosive dengue epidemics. DOI: http://dx.doi.org/10.7554/eLife.11285.001 PMID:26910315

Maturation, Peer Context, and Indigenous Girls' Early-Onset Substance Use

ERIC Educational Resources Information Center

Walls, Melissa L.; Whitbeck, Les B.

2011-01-01

This article examines a biosocial model of the impact of puberty on indigenous girls' early-onset substance use by considering the potential mediating role of peer context (i.e., mixed-sex peer groups and substance use prototypes) on the puberty and substance use relationship. Data include responses from 360 girls of a common indigenous cultural…

Development and clinical evaluation of an ionization chamber array with 3.5 mm pixel pitch for quality assurance in advanced radiotherapy techniques.

PubMed

Togno, M; Wilkens, J J; Menichelli, D; Oechsner, M; Perez-Andujar, A; Morin, O

2016-05-01

To characterize a new air vented ionization chamber technology, suitable to build detector arrays with small pixel pitch and independence of sensitivity on dose per pulse. The prototype under test is a linear array of air vented ionization chambers, consisting of 80 pixels with 3.5 mm pixel pitch distance and a sensitive volume of about 4 mm(3). The detector has been characterized with (60)Co radiation and MV x rays from different linear accelerators (with flattened and unflattened beam qualities). Sensitivity dependence on dose per pulse has been evaluated under MV x rays by changing both the source to detector distance and the beam quality. Bias voltage has been varied in order to evaluate the charge collection efficiency in the most critical conditions. Relative dose profiles have been measured for both flattened and unflattened distributions with different field sizes. The reference detectors were a commercial array of ionization chambers and an amorphous silicon flat panel in direct conversion configuration. Profiles of dose distribution have been measured also with intensity modulated radiation therapy (IMRT), stereotactic radiosurgery (SRS), and volumetric modulated arc therapy (VMAT) patient plans. Comparison has been done with a commercial diode array and with Gafchromic EBT3 films. Repeatability and stability under continuous gamma irradiation are within 0.3%, in spite of low active volume and sensitivity (∼200 pC/Gy). Deviation from linearity is in the range [0.3%, -0.9%] for a dose of at least 20 cGy, while a worsening of linearity is observed below 10 cGy. Charge collection efficiency with 2.67 mGy/pulse is higher than 99%, leading to a ±0.9% sensitivity change in the range 0.09-2.67 mGy/pulse (covering all flattened and unflattened beam qualities). Tissue to phantom ratios show an agreement within 0.6% with the reference detector up to 34 cm depth. For field sizes in the range 2 × 2 to 15 × 15 cm(2), the output factors are in agreement with a thimble chamber within 2%, while with 25 × 25 cm(2) field size, an underestimation of 4.0% was found. Agreement of field and penumbra width measurements with the flat panel is of the order of 1 mm down to 1 × 1 cm(2) field size. Flatness and symmetry values measured with the 1D array and the reference detectors are comparable, and differences are always smaller than 1%. Angular dependence of the detector, when compared to measurements taken with a cylindrical chamber in the same phantom, is as large as 16%. This includes inhomogeneity and asymmetry of the design, which during plan verification are accounted for by the treatment planning system (TPS). The detector is capable to reproduce the dose distributions of IMRT and VMAT plans with a maximum deviation from TPS of 3.0% in the target region. In the case of VMAT and SRS plans, an average (maximum) deviation of the order of 1% (4%) from films has been measured. The investigated technology appears to be useful both for Linac QA and patient plan verification, especially in treatments with steep dose gradients and nonuniform dose rates such as VMAT and SRS. Major limitations of the present prototype are the linearity at low dose, which can be solved by optimizing the readout electronics, and the underestimation of output factors with large field sizes. The latter problem is presently not completely understood and will require further investigations.

ARADISH - Development of a Standardized Plant Growth Chamber for Experiments in Gravitational Biology Using Ground Based Facilities

NASA Astrophysics Data System (ADS)

Schüler, Oliver; Krause, Lars; Görög, Mark; Hauslage, Jens; Kesseler, Leona; Böhmer, Maik; Hemmersbach, Ruth

2016-06-01

Plant development strongly relies on environmental conditions. Growth of plants in Biological Life Support Systems (BLSS), which are a necessity to allow human survival during long-term space exploration missions, poses a particular problem for plant growth, as in addition to the traditional environmental factors, microgravity (or reduced gravity such as on Moon or Mars) and limited gas exchange hamper plant growth. Studying the effects of reduced gravity on plants requires real or simulated microgravity experiments under highly standardized conditions, in order to avoid the influence of other environmental factors. Analysis of a large number of biological replicates, which is necessary for the detection of subtle phenotypical differences, can so far only be achieved in Ground Based Facilities (GBF). Besides different experimental conditions, the usage of a variety of different plant growth chambers was a major factor that led to a lack of reproducibility and comparability in previous studies. We have developed a flexible and customizable plant growth chamber, called ARAbidopsis DISH (ARADISH), which allows plant growth from seed to seedling, being realized in a hydroponic system or on Agar. By developing a special holder, the ARADISH can be used for experiments with Arabidopsis thaliana or a plant with a similar habitus on common GBF hardware, including 2D clinostats and Random Positioning Machines (RPM). The ARADISH growth chamber has a controlled illumination system of red and blue light emitting diodes (LED), which allows the user to apply defined light conditions. As a proof of concept we tested a prototype in a proteomic experiment in which plants were exposed to simulated microgravity or a 90° stimulus. We optimized the design and performed viability tests after several days of growth in the hardware that underline the utility of ARADISH in microgravity research.

Characterizing Microbe-Environment Interactions Through Experimental Evolution: The Autonomous Adaptive Directed Evolution Chamber

NASA Astrophysics Data System (ADS)

Ibanez, C. R.; Blaich, J.; Owyang, S.; Storrs, A.; Moffet, A.; Wong, N.; Zhou, J.; Gentry, D.

2015-12-01

We are developing a laboratory system for studying micro- to meso-scale interactions between microorganisms and their physicochemical environments. The Autonomous Adaptive Directed Evolution Chamber (AADEC) cultures microorganisms in controlled,small-scale geochemical environments. It observes corresponding microbial interactions to these environments and has the ability to adjust thermal, chemical, and other parameters in real time in response to these interactions. In addition to the sensed data, the system allows the generation of time-resolved ecological, genomic, etc. samples on the order of microbial generations. The AADEC currently houses cultures in liquid media and controls UVC radiation, heat exposure, and nutrient supply. In a proof-of-concept experimental evolution application, it can increase UVC radiation resistance of Escherichia coli cultures by iteratively exposing them to UVC and allowing the surviving cells to regrow. A baseline characterization generated a million fold resistance increase. This demonstration uses a single-well growth chamber prototype, but it was limited by scalability. We have expanded upon this system by implementing a microwell plate compatible fluidics system and sensor housing. This microwell plate system increases the diversity of microbial interactions seen in response to the geochemical environments generated by the system, allowing greater control over individual cultures' environments and detection of rarer events. The custom microfluidic card matches the footprint of a standard microwell plate. This card enables controllable fluid flow between wells and introduces multiple separate exposure and sensor chambers, increasing the variety of sensors compatible with the system. This gives the device control over scale and the interconnectedness of environments within the system. The increased controllability of the multiwell system provides a platform for implementing machine learning algorithms that will autonomously adjust geochemical environmental parameters.

Principle design and actuation of a dual chamber electromagnetic micropump with coaxial cantilever valves.

PubMed

Zordan, Enrico; Amirouche, Farid; Zhou, Yu

2010-02-01

This paper deals with the design and characterization of an electromagnetic actuation micropump with superimposed dual chambers. An integral part of microfluidic system includes micropumps which have become a critical design focus and have the potential to alter treatment and drug delivery requirements to patients. In this paper, conceptual design of variable geometrical nozzle/diffuser elements, coaxial cantilever valve, is proposed. It takes advantages of cantilever fluctuating valves with preset geometry to optimize and control fluid flow. The integration of this conceptual valve into a dual chamber micropump has increased the flow rate when compared to a single chamber micropump. This technique also allows for the fluid flow to be actively controlled by adjusting the movement of the intermediate membrane and the cantilever valves due to their fast response and large deflection properties when subjected to an electromagnetic field. To ensure reliability and performance of both the membrane and electromagnets, finite element method was used to perform the stress-strain analysis and optimize the membrane structure and electromagnet configuration. The frequency-dependent flow rates and backpressure are investigated for different frequencies by varying the applied currents from 1A to 1.75A. The current micropump design exhibits a backpressure of 58 mmH(2)O and has a water flow rate that reaches maximum at 1.985 ml/s under a 1.75A current with a resonance frequency of 45 Hz. This proposed micropump while at its initial prototype stage can satisfy the requirements of wide flow rate drug delivery applications. Its controllability and process design are attractive for high volume fabrication and low cost.

Testing a Regenerative Carbon Dioxide and Moisture Removal Technology

NASA Technical Reports Server (NTRS)

Barta, Daniel J.; Button, Amy; Sweterlitsch, Jeffrey J.; Curley, Suzanne

2010-01-01

The National Aeronautics and Space Administration supported the development of a new vacuum-desorbed regenerative carbon dioxide and humidity control technology for use in short duration human spacecraft. The technology was baselined for use in the Orion Crew Exploration Vehicle s Environmental Control and Life Support System (ECLSS). Termed the Carbon Dioxide And Moisture Removal Amine Swing-bed (CAMRAS), the unit was developed by Hamilton Sundstrand and has undergone extensive testing at Johnson Space Center. The tests were performed to evaluate performance characteristics under range of operating conditions and human loads expected in future spacecraft applications, as part of maturation to increase its readiness for flight. Early tests, conducted at nominal atmospheric pressure, used human metabolic simulators to generate loads, with later tests making us of human test subjects. During these tests many different test cases were performed, involving from 1 to 6 test subjects, with different activity profiles (sleep, nominal and exercise). These tests were conducted within the airlock portion of a human rated test chamber sized to simulate the Orion cabin free air volume. More recently, a test was completed that integrated the CAMRAS with a simulated suit loop using prototype umbilicals and was conducted at reduced atmospheric pressure and elevated oxygen levels. This paper will describe the facilities and procedures used to conduct these and future tests, and provide a summary of findings.

Development of a natural gas stratified charge rotary engine

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sierens, R.; Verdonck, W.

A water model has been used to determine the positions of separate inlet ports for a natural gas, stratified charge rotary engine. The flow inside the combustion chamber (mainly during the induction period) has been registered by a film camera. From these tests the best locations of the inlet ports have been obtained, a prototype of this engine has been built by Audi NSU and tested in the laboratories of the university of Gent. The results of these tests, for different stratification configurations, are given. These results are comparable with the best results obtained by Audi NSU for a homogeneousmore » natural gas rotary engine.« less

A T0/Trigger detector for the External Target Experiment at CSR

NASA Astrophysics Data System (ADS)

Hu, D.; Shao, M.; Sun, Y.; Li, C.; Chen, H.; Tang, Z.; Zhang, Y.; Zhou, J.; Zeng, H.; Zhao, X.; You, W.; Song, G.; Deng, P.; Lu, J.; Zhao, L.

2017-06-01

A new T0/Trigger detector based on multi-gap resistive plate chamber (MRPC) technology has been constructed and tested for the external target experiment (ETE) at HIRFL-CSR. It measures the multiplicity and timing information of particles produced in heavy-ion collisions at the target region, providing necessary event collision time (T0) and collision centrality with high precision. Monte-Carlo simulation shows a time resolution of several tens of picosecond can be achieved at central collisions. The experimental tests have been performed for this prototype detector at the CSR-ETE. The preliminary results are shown to demonstrate the performance of the T0/Trigger detector.

Rapid prototyping of versatile atom chips for atom interferometry applications.

NASA Astrophysics Data System (ADS)

Kasch, Brian; Squires, Matthew; Olson, Spencer; Kroese, Bethany; Imhof, Eric; Kohn, Rudolph; Stuhl, Benjamin; Schramm, Stacy; Stickney, James

2016-05-01

We present recent advances in the manipulation of ultracold atoms with ex-vacuo atom chips (i.e. atom chips that are not inside to the UHV chamber). Details will be presented of an experimental system that allows direct bonded copper (DBC) atom chips to be removed and replaced in minutes, requiring minimal re-optimization of parameters. This system has been used to create Bose-Einstein condensates, as well as magnetic waveguides with precisely tunable axial parameters, allowing double wells, pure harmonic confinement, and modified harmonic traps. We investigate the effects of higher order magnetic field contributions to the waveguide, and the implications for confined atom interferometry.

Wide-range structurally optimized channel for monitoring the certified power of small-core reactors

NASA Astrophysics Data System (ADS)

Koshelev, A. S.; Kovshov, K. N.; Ovchinnikov, M. A.; Pikulina, G. N.; Sokolov, A. B.

2016-12-01

The results of tests of a prototype version of a channel for monitoring the certified power of small-core reactors performed at the BR-K1 reactor at the All-Russian Scientific Research Institute of Experimental Physics are reported. An SNM-11 counter and commercial KNK-4 and KNK-3 compensated ion chambers were used as neutron detectors in the tested channel, and certified NCMM and CCMM measurement modules controlled by a PC with specialized software were used as measuring instruments. The specifics of metrological assurance of calibration of the channel in the framework of reactor power monitoring are discussed.

A review of Curtiss-Wright rotary engine developments with respect to general aviation potential

NASA Technical Reports Server (NTRS)

Jones, C.

1979-01-01

Aviation related rotary (Wankel-type) engine tests, possible growth directions and relevant developments at Curtiss-Wright have been reviewed. Automotive rotary engines including stratified charge are described and flight test results of rotary aircraft engines are presented. The current 300 HP engine prototype shows basic durability and competitive performance potential. Recent parallel developments have separately confirmed the geometric advantages of the rotary engine for direct injected unthrottled stratified charge. Specific fuel consumption equal to or better than pre- or swirl-chamber diesels, low emission and multi-fuel capability have been shown by rig tests of similar rotary engine.

NASA KSC Intern Final Paper

NASA Technical Reports Server (NTRS)

Colton, Andrew

2012-01-01

I am finishing up my internship with the Application & Simulation group at NASA Kennedy Space Center (KSC). During this internship I was working with the Plant Habitat development team. The Plant Habitat provides a large enclosed, environmentally controlled chamber designed to support commercial and fundamental plant research onboard the International Space Station (ISS). The work that I did was for the prototype of the Graphical User Interface (GUI) display. This display is used by the scientists to monitor the system health, start new experiment configurations, and get real-time information about the experiment as its being run. This display is developed using the Qt Framework Integrated Development Environment (IDE) and the programming language C++.

Wide-range structurally optimized channel for monitoring the certified power of small-core reactors

DOE Office of Scientific and Technical Information (OSTI.GOV)

Koshelev, A. S., E-mail: alexsander.coshelev@yandex.ru; Kovshov, K. N.; Ovchinnikov, M. A.

The results of tests of a prototype version of a channel for monitoring the certified power of small-core reactors performed at the BR-K1 reactor at the All-Russian Scientific Research Institute of Experimental Physics are reported. An SNM-11 counter and commercial KNK-4 and KNK-3 compensated ion chambers were used as neutron detectors in the tested channel, and certified NCMM and CCMM measurement modules controlled by a PC with specialized software were used as measuring instruments. The specifics of metrological assurance of calibration of the channel in the framework of reactor power monitoring are discussed.

Development of a high-resolution liquid xenon detector for gamma-ray astrophysics

NASA Astrophysics Data System (ADS)

Mukherjee, Reshmi

It has been shown here that liquid xenon is one of the most promising detector media for future gamma-ray detectors, owing to an excellent combination of physical properties. The feasibility of the construction of a high resolution liquid xenon detector as a gamma-ray detector for astrophysics has been demonstrated. Up to 3.5 liters of liquid xenon has been successfully purified and using both small and large volume prototypes, the charge and the energy resolution response of such detectors to gamma-rays, internal conversion electrons and alpha particles have been measured. The best energy resolution measured was 4.5 percent FWHM at 1 MeV. Cosmic ray tracks have been imaged using a 2-dimensional liquid xenon multiwire imaging chamber. The spatial resolution along the direction of the drifting electrons was 180 microns rms. Experiments have been performed to study the scintillation light in liquid xenon, as the prompt scintillation signal in the liquid is an electron-ion pair in liquid krypton was measured for the first time with a pulsed ionization chamber to be 18.4 plus or minus 0.3 eV.

Additive manufacturing of magnetic shielding and ultra-high vacuum flange for cold atom sensors.

PubMed

Vovrosh, Jamie; Voulazeris, Georgios; Petrov, Plamen G; Zou, Ji; Gaber, Youssef; Benn, Laura; Woolger, David; Attallah, Moataz M; Boyer, Vincent; Bongs, Kai; Holynski, Michael

2018-01-31

Recent advances in the understanding and control of quantum technologies, such as those based on cold atoms, have resulted in devices with extraordinary metrological performance. To realise this potential outside of a lab environment the size, weight and power consumption need to be reduced. Here we demonstrate the use of laser powder bed fusion, an additive manufacturing technique, as a production technique relevant to the manufacture of quantum sensors. As a demonstration we have constructed two key components using additive manufacturing, namely magnetic shielding and vacuum chambers. The initial prototypes for magnetic shields show shielding factors within a factor of 3 of conventional approaches. The vacuum demonstrator device shows that 3D-printed titanium structures are suitable for use as vacuum chambers, with the test system reaching base pressures of 5 ± 0.5 × 10 -10 mbar. These demonstrations show considerable promise for the use of additive manufacturing for cold atom based quantum technologies, in future enabling improved integrated structures, allowing for the reduction in size, weight and assembly complexity.

Achieving and documenting closure in plant growth facilities

NASA Technical Reports Server (NTRS)

Knott, W. M.; Sager, John C.; Wheeler, Ray

1992-01-01

As NASA proceeds with its effort to develop a Controlled Ecological Life Support System (CELSS) that will provide life support to crews during long duration space missions, it must address the question of facility and system closure. The concept of closure as it pertains to CELSS and engineering specifications, construction problems and monitoring procedures used in the development and operation of a closed plant growth facility for the CELSS program are described. A plant growth facility is one of several modules required for a CELSS. A prototype of this module at Kennedy Space Center is the large (7m tall x 3.5m diameter) Biomass Production Chamber (BPC), the central facility of the CELSS Breadboard Project. The BPC is atmospherically sealed to a leak rate of approximately 5 percent of its total volume per 24 hours. This paper will discuss the requirements for atmospheric closure in the facility, present CO2 and trace gas data from initial tests of the BPC with and without plants, and describe how the chamber was sealed atmospherically. Implications that research conducted in this type of facility will have for the CELSS program are discussed.

A targeted ferritin-microplasmin based thrombolytic nanocage selectively dissolves blood clots.

PubMed

Seo, Junyoung; Al-Hilal, Taslim A; Jee, Jun-Goo; Kim, Yong-Lim; Kim, Ha-Jeong; Lee, Byung-Heon; Kim, Soyoun; Kim, In-San

2018-04-01

The use of thrombolytic therapies is limited by an increased risk of systemic hemorrhage due to lysis of hemostatic clots. We sought to develop a plasmin-based thrombolytic nanocage that efficiently dissolves the clot without causing systemic fibrinolysis or disrupting hemostatic clots. Here, we generated a double chambered short-length ferritin (sFt) construct that has an N-terminal region fused to multivalent clot targeting peptides (CLT: CNAGESSKNC) and a C-terminal end fused to a microplasmin (μPn); CLT recognizes fibrin-fibronectin complexes in clots, μPn efficiently dissolves clots, and the assembly of double chambered sFt (CLT-sFt-μPn) into nanocage structure protects the activated-μPn from its circulating inhibitors. Importantly, activated CLT-sFt-μPn thrombolytic nanocage showed a prolonged circulatory life over activated-μPn and efficiently lysed the preexisting clots in both arterial and venous thromboses models. Thus, CLT-sFt-μPn thrombolytic nanocage platform represents the prototype of a targeted clot-busting agent with high efficacy and safety over existing thrombolytic therapies. Copyright © 2018 Elsevier Inc. All rights reserved.

Mechanically activated artificial cell by using microfluidics

NASA Astrophysics Data System (ADS)

Ho, Kenneth K. Y.; Lee, Lap Man; Liu, Allen P.

2016-09-01

All living organisms sense mechanical forces. Engineering mechanosensitive artificial cell through bottom-up in vitro reconstitution offers a way to understand how mixtures of macromolecules assemble and organize into a complex system that responds to forces. We use stable double emulsion droplets (aqueous/oil/aqueous) to prototype mechanosensitive artificial cells. In order to demonstrate mechanosensation in artificial cells, we develop a novel microfluidic device that is capable of trapping double emulsions into designated chambers, followed by compression and aspiration in a parallel manner. The microfluidic device is fabricated using multilayer soft lithography technology, and consists of a control layer and a deformable flow channel. Deflections of the PDMS membrane above the main microfluidic flow channels and trapping chamber array are independently regulated pneumatically by two sets of integrated microfluidic valves. We successfully compress and aspirate the double emulsions, which result in transient increase and permanent decrease in oil thickness, respectively. Finally, we demonstrate the influx of calcium ions as a response of our mechanically activated artificial cell through thinning of oil. The development of a microfluidic device to mechanically activate artificial cells creates new opportunities in force-activated synthetic biology.

Twin-Screw Extruder and Pellet Accelerator Integration Developments for ITER

DOE Office of Scientific and Technical Information (OSTI.GOV)

Meitner, Steven J; Baylor, Larry R; Combs, Stephen Kirk

The ITER pellet injection system consisting of a twinscrew frozen hydrogen isotope extruder, coupled to a combination solenoid actuated pellet cutter and pneumatic pellet accelerator, is under development at the Oak Ridge National Laboratory. A prototype extruder has been built to produce a continuous solid deuterium extrusion and will be integrated with a secondary section, where pellets are cut, chambered, and launched with a single-stage pneumatic accelerator into the plasma through a guide tube. This integrated pellet injection system is designed to provide 5 mm fueling pellets, injected at a rate up to 10 Hz, or 3 mm edge localizedmore » mode (ELM) triggering pellets, injected at higher rates up to 20 Hz. The pellet cutter, chamber mechanism, and the solenoid operated pneumatic valve for the accelerator are optimized to provide pellet velocities between 200-300 m/s to ensure high pellet survivability while traversing the inner wall fueling guide tubes, and outer wall ELMpacing guide tubes. This paper outlines the current twin-screwextruder design, pellet accelerator design, and the integrationrequired for both fueling and ELM pacing pellets.« less

Performance of a Drift Chamber Candidate for a Cosmic Muon Tomography System

NASA Astrophysics Data System (ADS)

Anghel, V.; Armitage, J.; Botte, J.; Boudjemline, K.; Bueno, J.; Bryman, D.; Charles, E.; Cousins, T.; Drouin, P.-L.; Erlandson, A.; Gallant, G.; Jewett, C.; Jonkmans, G.; Liu, Z.; Noel, S.; Oakham, G.; Stocki, T. J.; Thompson, M.; Waller, D.

2011-12-01

In the last decade, many groups around the world have been exploring different ways to probe transport containers which may contain illicit Special Nuclear Materials such as uranium. The muon tomography technique has been proposed as a cost effective system with an acceptable accuracy. A group of Canadian institutions (see above), funded by Defence Research and Development Canada, is testing different technologies to track the cosmic muons. One candidate is the single wire Drift Chamber. With the capability of a 2D impact position measurement, two detectors will be placed above and two below the object to be probed. In order to achieve a good 3D image quality of the cargo content, a good angular resolution is required. The simulation showed that 1mrad was required implying the spatial resolution of the trackers must be in the range of 1 to 2 mm for 1 m separation. A tracking system using three prototypes has been built and tested. The spatial resolution obtained is 1.7 mm perpendicular to the wire and 3 mm along the wire.

Deep Space 1 Ion Engine

NASA Image and Video Library

2002-12-21

This image of a xenon ion engine prototype, photographed through a port of the vacuum chamber where it was being tested at NASA's Jet Propulsion Laboratory, shows the faint blue glow of charged atoms being emitted from the engine. The engine is now in an ongoing extended- life test, in a vacuum test chamber at JPL, and has run for almost 500 days (12,000 hours) and is scheduled to complete nearly 625 days (15,000 hours) by the end of 2001. A similar engine powers the New Millennium Program's flagship mission, Deep Space 1, which uses the ion engine in a trip through the solar system. The engine, weighing 17.6 pounds (8 kilograms), is 15.7 inches (40 centimeters) in diameter and 15.7 inches long. The actual thrust comes from accelerating and expelling positively charged xenon atoms, or ions. While the ions are fired in great numbers out the thruster at more than 110,000 kilometers (68,000 miles) per hour, their mass is so low that the engine produces a gentle thrust of only 90 millinewtons (20-thousandths of a pound). http://photojournal.jpl.nasa.gov/catalog/PIA04238

Comparison of the performance of different instruments in the stray neutron field around the CERN Proton Synchrotron.

PubMed

Aza, Eleni; Caresana, Marco; Cassell, Christopher; Colombo, Valeria; Damjanovic, Sanja; Gilardoni, Simone; Manessi, Giacomo Paolo; Pangallo, Michel; Perrin, Daniel; Silari, Marco

2014-10-01

This paper discusses an intercomparison campaign carried out in several locations around the CERN Proton Synchrotron. The locations were selected in order to perform the measurements in different stray field conditions. Various neutron detectors were employed: ionisation chambers, conventional and extended range rem counters, both commercial and prototype ones, including a novel instrument called LUPIN, specifically conceived to work in pulsed fields. The attention was focused on the potential differences in the instrument readings due to dead-time losses that are expected to affect most commercial units. The results show that the ionisation chambers and LUPIN agree well with the expected H*(10) values, as derived from FLUKA simulations, showing no relevant underestimations even in strongly pulsed fields. On the contrary, the dead-time losses of the other rem counters induced an underestimation in pulsed fields that was more important for instruments characterised by a higher dead time. © The Author 2013. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Detection of occult pericardial hemorrhage early after open-heart surgery using technetium-99m red blood cell radionuclide ventriculography

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bateman, T.M.; Czer, L.S.; Gray, R.J.

1984-11-01

Pericardial or mediastinal hemorrhage requiring reoperation occurs in 2% to 5% of patients, usually early (0 to 48 hours), after open-heart surgery. This hemorrhage may be occult, and resulting cardiac tamponade may easily be misinterpreted as ventricular dysfunction, common early postoperatively. In such cases, appropriate and timely intervention may not occur. Of 50 patients evaluated by technetium-99m red blood cell gated equilibrium radionuclide ventriculography (RNV) because of early postoperative cardiogenic shock of uncertain etiology, 17 had unique scintigraphic images suggestive of intrathoracic hemorrhage. Of these 17, 5 had a generalized halo of abnormal radioactivity surrounding small hyperdynamic right and leftmore » ventricles, 11 had localized regions of intense blood pool activity outside the cardiac chambers (two with compression of single chambers), and one demonstrated marked radionuclide activity in the right hemithorax (2000 ml of blood at reoperation). Twelve patients had exploratory reoperation for control of hemorrhage as a direct result of the scintigraphic findings, three were successfully treated with fresh frozen plasma and platelet infusions along with medical interventions to optimize cardiac performance, and two patients died in cardiogenic shock (presumed tamponade) without reoperation. In the 12 reoperated patients, all were confirmed to have active pericardial bleeding. Scintigraphic localization of abnormal blood pools within the pericardium corresponded to the sites at which active bleeding was witnessed at reoperation. The abnormal bleeding was etiologically related to the tamponade state, with marked improvement in hemodynamics after reoperation. Nine additional patients were reoperated for presumed tamponade after RNV revealed an exaggerated halo of photon deficiency surrounding the cardiac chambers.« less

Optimized Vibration Chamber for Landslide Sensory and Alarm System

NASA Astrophysics Data System (ADS)

Ismail, Eliza Sabira Binti; Hadi Habaebi, Mohamed; Daoud, Jamal I.; Rafiqul Islam, Md

2017-11-01

Landslide is one of natural hazard that is not unfamiliar disaster in Malaysia. Malaysia has experienced this disaster many times since 1969. This natural hazard has become a major research concern for Malaysian government when many people were injured badly and even had been killed. Many previous research works published in the open literature aimed at designing a system that could detect landslide in early stage before the landslide becomes catastrophic. This paper presents the early works on a major work-in-progress landslide early warning system for Malaysian environment. The aim of this system is to develop the most efficiently reliable cost-effective system in which slight earth movements are monitored continuously. The challenge this work aims at is to work with a low budget system that produces efficient performance. Hence, the material used is off-the-shelf. Early design optimization results of the vibration sensor used is quite promising detecting the slightest faint tremors, which are amplified using the best vibration chamber available. It is shown that the choice of proper pipe length and diameter dimensions in combination to a gravel to exaggerate the produced higher sensitivity level noise of 5 dB.

On the manufacturing of a gas turbine engine part through metal spinning process

NASA Astrophysics Data System (ADS)

Hassanin, A. El; Astarita, A.; Scherillo, F.; Velotti, C.; Squillace, A.; Liguori, A.

2018-05-01

Metal spinning processes represents an interesting alternative to traditional sheet metal forming processes in several industrial contexts, such as automotive and aerospace. In this work, the production of a combustion chamber liner top prototype using AISI 304L stainless steel is proposed, in order to evaluate the process feasibility for the required part geometry. The prototypes production was carried out using a two-stage semiautomatic spinning process. The effects in terms of wall thickness reduction were investigated. Using optical microscopy and Scanning Electron Microscopy (SEM) techniques, the microstructural behavior of the metal subjected to the forming process was investigated, while for an evaluation of the influence on the mechanical properties Vickers micro-indentation tests were performed. The main result of the process, as observed from all the investigation techniques adopted, is the formation of strain induced martensite due to the severe plastic deformation and cold reduction of the material, ranging in this case from 30% to 50%. In some areas of the part section, some rips indicating an excessive tensile stress were also detected.

Double-Acting Sleeve Muscle Actuator for Bio-Robotic Systems.

PubMed

Zheng, Hao; Shen, Xiangrong

2013-11-25

This paper presents a new type of muscle-like actuator, namely double-acting (DA) sleeve muscle actuator, which is suitable for the actuation of biologically-inspired and biomedical robotic systems, especially those serving human-assistance purposes (prostheses, orthoses, etc .). Developed based on the traditional pneumatic muscle actuator, the new DA sleeve muscle incorporates a unique insert at the center. With the insert occupying the central portion of the internal volume, this new actuator enjoys multiple advantages relative to the traditional pneumatic muscle, including a consistent increase of force capacity over the entire range of motion, and a significant decrease of energy consumption in operation. Furthermore, the insert encompasses an additional chamber, which generates an extension force when pressurized. As such, this new actuator provides a unique bi-directional actuation capability, and, thus, has a potential to significantly simplify the design of a muscle actuator-powered robotic system. To demonstrate this new actuator concept, a prototype has been designed and fabricated, and experiments conducted on this prototype demonstrated the enhanced force capacity and the unique bi-directional actuation capability.

Theoretical and experimental studies of a magnetically actuated valveless micropump

NASA Astrophysics Data System (ADS)

Ashouri, Majid; Behshad Shafii, Mohammad; Moosavi, Ali

2017-01-01

This paper presents the prototype design, fabrication, and characterization of a magnetically actuated micropump. The pump body consists of three nozzle/diffuser elements and two pumping chambers connected to the ends of a flat-wall pumping cylinder. A cylindrical permanent magnet placed inside the pumping cylinder acts as a piston which reciprocates by using an external magnetic actuator driven by a motor. The magnetic piston is covered by a ferrofluid to provide self-sealing capability. A prototype composed of three bonded layers of polymethyl-methacrylate (PMMA) has been fabricated. Water has been successfully pumped at pressures of up to 750 Pa and flow rates of up to 700 µl min-1 while working at the piston actuation frequency of 4 and 5 Hz, respectively. 3D numerical simulations are also carried out to study the performance of the pump. The best experimental and numerical volumetric efficiency of the pump are about 7 and 8%, respectively, at the piston speed of 0.03 m s-1. The contactless external actuation feature of the design enables integration of the pump with other PMMA-based microfluidic systems with low cost and disposability.

Advanced radiator concepts utilizing honeycomb panel heat pipes

NASA Technical Reports Server (NTRS)

Fleischman, G. L.; Peck, S. J.; Tanzer, H. J.

1987-01-01

The feasibility of fabricating and processing moderate temperature range vapor chamber type heat pipes in a low mass honeycomb panel configuration for highly efficient radiator fins for potential use on the space station was investigated. A variety of honeycomb panel facesheet and core-ribbon wick concepts were evaluated within constraints dictated by existing manufacturing technology and equipment. Concepts evaluated include type of material, material and panel thickness, wick type and manufacturability, liquid and vapor communication among honeycomb cells, and liquid flow return from condenser to evaporator facesheet areas. A thin-wall all-welded stainless steel design with methanol as the working fluid was the initial prototype unit. It was found that an aluminum panel could not be fabricated in the same manner as a stainless steel panel due to diffusion bonding and resistance welding considerations. Therefore, a formed and welded design was developed. The prototype consists of ten panels welded together into a large panel 122 by 24 by 0.15 in., with a heat rejection capability of 1000 watts and a fin efficiency of essentially 1.0.

The Effects of Sleep Deprivation on Dissociable Prototype Learning Systems

PubMed Central

Maddox, W. Todd; Glass, Brian D.; Zeithamova, Dagmar; Savarie, Zachary R.; Bowen, Christopher; Matthews, Michael D.; Schnyer, David M.

2011-01-01

Background: The cognitive neural underpinnings of prototype learning are becoming clear. Evidence points to 2 different neural systems, depending on the learning parameters. A/not-A (AN) prototype learning is mediated by posterior brain regions that are involved in early perceptual learning, whereas A/B (AB) is mediated by frontal and medial temporal lobe regions. Study Objectives: To investigate the effects of sleep deprivation on AN and AB prototype learning and to use established prototype models to provide insights into the cognitive-processing locus of sleep-deprivation deficits. Design: Participants performed an AN and an AB prototype learning task twice, separated by a 24-hour period, with or without sleep between testing sessions. Participants: Eighteen West Point cadets participated in the sleep-deprivation group, and 17 West Point cadets participated in a control group. Measurements and Results: Sleep deprivation led to an AN, but not an AB, performance deficit. Prototype model analyses indicated that the AN deficit was due to changes in attentional focus and a decrease in confidence that is reflected in an increased bias to respond non-A. Conclusions: The findings suggest that AN, but not AB, prototype learning is affected by sleep deprivation. Prototype model analyses support the notion that the effect of sleep deprivation on AN is consistent with lapses in attentional focus that are more detrimental to AN than to AB. This finding adds to a growing body of work that suggests that different performance changes associated with sleep deprivation can be attributed to a common mechanism of changes in simple attention and vigilance. Citation: Maddox WT; Glass BD; Zeithamova D; Savarie ZR; Bowen C; Matthews MD; Schnyer DM. The effects of sleep deprivation on dissociable prototype learning systems. SLEEP 2011;34(3):253-260. PMID:21358842

EVA Suit R and D for Performance Optimization

NASA Technical Reports Server (NTRS)

Cowley, Matthew S.; Harvill, Lauren; Benson, Elizabeth; Rajulu, Sudhakar

2014-01-01

Designing a planetary suit is very complex and often requires difficult trade-offs between performance, cost, mass, and system complexity. To verify that new suit designs meet requirements, full prototypes must be built and tested with human subjects. However, numerous design iterations will occur before the hardware meets those requirements. Traditional draw-prototype-test paradigms for R&D are prohibitively expensive with today's shrinking Government budgets. Personnel at NASA are developing modern simulation techniques which focus on human-centric designs by creating virtual prototype simulations and fully adjustable physical prototypes of suit hardware. During the R&D design phase, these easily modifiable representations of an EVA suit's hard components will allow designers to think creatively and exhaust design possibilities before they build and test working prototypes with human subjects. It allows scientists to comprehensively benchmark current suit capabilities and limitations for existing suit sizes and sizes that do not exist. This is extremely advantageous and enables comprehensive design down-selections to be made early in the design process, enables the use of human performance as design criteria, and enables designs to target specific populations

Early Rockets

NASA Image and Video Library

2004-04-15

This photograph is of the engine for the Redstone rocket. The Redstone ballistic missile was a high-accuracy, liquid-propelled, surface-to-surface missile developed by the Army Ballistic Missile Agency, Redstone Arsenal, in Huntsville, Alabama, under the direction of Dr. von Braun. The Redstone engine was a modified and improved version of the Air Force's Navaho cruise missile engine of the late forties. The A-series, as this would be known, utilized a cylindrical combustion chamber as compared with the bulky, spherical V-2 chamber. By 1951, the Army was moving rapidly toward the design of the Redstone missile, and the production was begun in 1952. Redstone rockets became the "reliable workhorse" for America's early space program. As an example of its versatility, the Redstone was utilized in the booster for Explorer 1, the first American satellite, with no major changes to the engine or missile.

Early Rockets

NASA Image and Video Library

2004-04-15

The image depicts Redstone missile being erected. The Redstone ballistic missile was a high-accuracy, liquid-propelled, surface-to-surface missile developed by Army Ballistic Missile Agency, Redstone Arsenal, in Huntsville, Alabama, under the direction of Dr. von Braun. The Redstone engine was a modified and improved version of the Air Force's Navaho cruise missile engine of the late forties. The A-series, as this would be known, utilized a cylindrical combustion chamber as compared with the bulky, spherical V-2 chamber. By 1951, the Army was moving rapidly toward the design of the Redstone missile, and the production was begun in 1952. Redstone rockets became the "reliable workhorse" for America's early space program. As an example of the versatility, Redstone was utilized in the booster for Explorer 1, the first American satellite, with no major changes to the engine or missile

Recent Progress on the Stretched Lens Array (SLA)

NASA Technical Reports Server (NTRS)

O'Neill, Markl; McDanal, A. J.; Piszczor, Michael; George, Patrick; Eskenazi, Michael; Botke, Matthew; Edwards, David; Hoppe, David; Brandhorst, Henry

2005-01-01

At the last Space Photovoltaic Research and Technology Conference, SPRAT XVII, held during the fateful week of 9/11/01, our team presented a paper on the early developments related to the new Stretched Lens Array (SLA), including its evolution from the successful SCARLET array on the NASA/JPL Deep Space 1 spacecraft. Within the past two years, the SLA team has made significant progress in the SLA technology, including the successful fabrication and testing of a complete four-panel prototype solar array wing (Fig. 1). The prototype wing verified the mechanical and structural design of the rigid-panel SLA approach, including multiple successful demonstrations of automatic wing deployment. One panel in the prototype wing included four fully functional photovoltaic receivers, employing triple-junction solar cells.

Decreased fertility in mice exposed to environmental air pollution in the city of Sao Paulo.

PubMed

Mohallem, Soraya Vecci; de Araújo Lobo, Débora Jã; Pesquero, Célia Regina; Assunção, João Vicente; de Andre, Paulo Afonso; Saldiva, Paulo Hilário Nascimento; Dolhnikoff, Marisa

2005-06-01

It has largely been shown that air pollution can affect human health. Effects on human fertility have been shown mainly in males by a decrease in semen quality. Few studies have focused on the environmental effects on female fertility. The aim of the present study was to analyze the effects of air pollution in the city of Sao Paulo on mouse female fertility. Four groups of female Balb/c mice were placed in two chambers 10 days (newborn) or 10 weeks (adults) after birth. Mice were maintained in the chambers 24 h a day, 7 days a week, for 4 months. The first chamber received air that had passed through an air filter (clean chamber) and the second received ambient air (polluted chamber). We measured PM10 and NO2 inside both chambers. Mice belonging to the adult groups were bred to male mice after living for 3 months inside the chambers. The newborn groups mated after reaching reproductive age (12 weeks). After 19 days of pregnancy the numbers of live-born pups, reabsorptions, fetal deaths, corpora lutea, and implantation failures were determined. PM10 and NO2 concentrations in the clean chamber were 50% and 77.5% lower than in the polluted chamber, respectively. Differences in fertility parameters between groups were observed only in animals exposed to air pollution at an early age (10 days after birth). We observed a higher number of live-born pups per animal in the clean chamber than per animal from the polluted chamber (median=6.0 and 4.0, respectively; P=0.037). There was a higher incidence of implantation failures in the polluted group than in the clean group (median=3.5 and 2.0, respectively; P=0.048). There were no significant differences in the other reproductive parameters between groups. These results support the concept that female reproductive health represents a target of air pollutants.

To Create Space on Earth: The Space Environment Simulation Laboratory and Project Apollo

NASA Technical Reports Server (NTRS)

Walters, Lori C.

2003-01-01

Few undertakings in the history of humanity can compare to the great technological achievement known as Project Apollo. Among those who witnessed Armstrong#s flickering television image were thousands of people who had directly contributed to this historic moment. Amongst those in this vast anonymous cadre were the personnel of the Space Environment Simulation Laboratory (SESL) at the Manned Spacecraft Center (MSC) in Houston, Texas. SESL houses two large thermal-vacuum chambers with solar simulation capabilities. At a time when NASA engineers had a limited understanding of the effects of extremes of space on hardware and crews, SESL was designed to literally create the conditions of space on Earth. With interior dimensions of 90 feet in height and a 55-foot diameter, Chamber A dwarfed the Apollo command/service module (CSM) it was constructed to test. The chamber#s vacuum pumping capacity of 1 x 10(exp -6) torr can simulate an altitude greater than 130 miles above the Earth. A "lunar plane" capable of rotating a 150,000-pound test vehicle 180 deg replicates the revolution of a craft in space. To reproduce the temperature extremes of space, interior chamber walls cool to -280F as two banks of carbon arc modules simulate the unfiltered solar light/heat of the Sun. With capabilities similar to that of Chamber A, early Chamber B tests included the Gemini modular maneuvering unit, Apollo EVA mobility unit and the lunar module. Since Gemini astronaut Charles Bassett first ventured into the chamber in 1966, Chamber B has assisted astronauts in testing hardware and preparing them for work in the harsh extremes of space.

Clinical Profile and Early Complications after Single and Dual Chamber Permanent Pacemaker Implantation at Manmohan Cardiothoracic Vascular and Transplant Centre, Kathmandu, Nepal.

PubMed

Khanal, J; Poudyal, R R; Devkota, S; Thapa, S; Dhungana, R R

2015-01-01

Permanent pacemaker implantation is a minimally invasive surgical procedure in the management of patients with cardiac problems. However, complications during and after implantation are not uncommon. There is lack of evidences in rate of complications with the selection of pacemakers in Nepal. Therefore, this study was performed to compare the frequency of implantation and complication rate between single chamber and dual chamber pacemaker. The present study is based on all consecutive pacemaker implantations in a single centre between April 2014 and May 2015. A total of 116 patients were categorized into two cohorts according to the type of pacemaker implanted- single chamber or dual chamber. All patients had regular 2-weeks follow-up intervals with standardized documentation of all relevant patient data till 6-week after implantation. Data were presented as means ± standard deviation (SD) for continuous variables and as proportions for categorical variables. Comparison of continuous variables between the groups was made with independent Student's t-test. For discrete variables distribution between groups were compared with Chi-square test. The mean age (±SD) of total population at implant was 64.08 (± 15.09) years. Dual chamber units were implanted in 44 (37.93%) of patients, single chamber in 72 (62.06%). Only 14 women (31.81%) received dual chamber compared with 42 women (58.33%) who received single chamber (Chi-square=18, DF=1, P = 0.0084). Complete atrioventricular block was the commonest (56.03%) indication for permanent pacemaker insertion followed by sick sinus syndrome (33.62%), symptomatic high-grade AV block (11.20%). Hypertension (dual chamber 21.55%, single chamber 40.51%) was the most common comorbidity in both cohorts. Complications occurred in 11 (9.48%) patients. More proportion of complication occurred in single chamber group (9 patients, 12.50%) than in dual chamber (2 patients, 4.54%). Complications occurring in dual chamber group include pocket hematoma 1 patient (2.27%) and arrhythmia in 1 patient (2.27%). Similarly, complications occurring in single chamber include RV perforation in two patients (2.77%) and one each (1.38%) had pocket hematoma, pneumothorax, infection, swelling at pocket site, arrhythmia in the form of NSVT, leads displacement, DVT and mortality. Women were more likely to receive single chamber systems than men. More proportion of complication occurred in single chamber group than in dual chamber. Future prospective studies on larger number of patients are needed to confirm and support our findings.

Patient-specific core decompression surgery for early-stage ischemic necrosis of the femoral head

PubMed Central

Wang, Wei; Hu, Wei; Yang, Pei; Dang, Xiao Qian; Li, Xiao Hui; Wang, Kun Zheng

2017-01-01

Introduction Core decompression is an efficient treatment for early stage ischemic necrosis of the femoral head. In conventional procedures, the pre-operative X-ray only shows one plane of the ischemic area, which often results in inaccurate drilling. This paper introduces a new method that uses computer-assisted technology and rapid prototyping to enhance drilling accuracy during core decompression surgeries and presents a validation study of cadaveric tests. Methods Twelve cadaveric human femurs were used to simulate early-stage ischemic necrosis. The core decompression target at the anterolateral femoral head was simulated using an embedded glass ball (target). Three positioning Kirschner wires were drilled into the top and bottom of the large rotor. The specimen was then subjected to computed tomography (CT). A CT image of the specimen was imported into the Mimics software to construct a three-dimensional model including the target. The best core decompression channel was then designed using the 3D model. A navigational template for the specimen was designed using the Pro/E software and manufactured by rapid prototyping technology to guide the drilling channel. The specimen-specific navigation template was installed on the specimen using positioning Kirschner wires. Drilling was performed using a guide needle through the guiding hole on the templates. The distance between the end point of the guide needle and the target was measured to validate the patient-specific surgical accuracy. Results The average distance between the tip of the guide needle drilled through the guiding template and the target was 1.92±0.071 mm. Conclusions Core decompression using a computer-rapid prototyping template is a reliable and accurate technique that could provide a new method of precision decompression for early-stage ischemic necrosis. PMID:28464029

Patient-specific core decompression surgery for early-stage ischemic necrosis of the femoral head.

PubMed

Wang, Wei; Hu, Wei; Yang, Pei; Dang, Xiao Qian; Li, Xiao Hui; Wang, Kun Zheng

2017-01-01

Core decompression is an efficient treatment for early stage ischemic necrosis of the femoral head. In conventional procedures, the pre-operative X-ray only shows one plane of the ischemic area, which often results in inaccurate drilling. This paper introduces a new method that uses computer-assisted technology and rapid prototyping to enhance drilling accuracy during core decompression surgeries and presents a validation study of cadaveric tests. Twelve cadaveric human femurs were used to simulate early-stage ischemic necrosis. The core decompression target at the anterolateral femoral head was simulated using an embedded glass ball (target). Three positioning Kirschner wires were drilled into the top and bottom of the large rotor. The specimen was then subjected to computed tomography (CT). A CT image of the specimen was imported into the Mimics software to construct a three-dimensional model including the target. The best core decompression channel was then designed using the 3D model. A navigational template for the specimen was designed using the Pro/E software and manufactured by rapid prototyping technology to guide the drilling channel. The specimen-specific navigation template was installed on the specimen using positioning Kirschner wires. Drilling was performed using a guide needle through the guiding hole on the templates. The distance between the end point of the guide needle and the target was measured to validate the patient-specific surgical accuracy. The average distance between the tip of the guide needle drilled through the guiding template and the target was 1.92±0.071 mm. Core decompression using a computer-rapid prototyping template is a reliable and accurate technique that could provide a new method of precision decompression for early-stage ischemic necrosis.

The Sr, Nd and O isotopic studies of the 1991 1995 eruption at Unzen, Japan

NASA Astrophysics Data System (ADS)

Chen, Chang-Hwa; Nakada, Setsuya; Shieh, Yuch-Ning; DePaolo, Donald J.

1999-04-01

The magma generation at Unzen volcano may be considered as the product of crustal material mixed with mantle magma accompanied by fractional crystallization (AFC). The magma in the Unzen volcano is estimated to consist of about 50-80% of residual magma ( F) and about 30-70% assimilated crustal material ( A) relative to the original magma. Concerning the 1991-1995 eruption, it is estimated that the magma formed as the result of mixing of about 50-60% crustal material and about 55-65% of residual magma. An alternative magma eruption model for the 1991-1995 eruption is proposed here. In the early stage, the isotopic characteristics of 1991 eruption are defined by AFC process in the deeper magma chamber. Later, the magma ascended through the conduit and quiescently stayed for a long time in a shallow reservoir before eruption. The minerals continuously crystallized as phenocrysts especially at the chilled top and outer margin in the shallow chamber. The crystallized phenocryst mush was reworked into the central part of the magma chamber by means of magma convection and rapid magma ascent. Therefore, the reaction between phenocrysts and melt occurs only in internal chemical disequilibrium in the magma chamber. In contrast, the isotopic compositions of the original magma shall be little influenced by the above processes throughout its eruptive history. The 1991-1995 eruptive rocks of the Unzen volcano show their characteristics in Sr and Nd isotopic values independent of their two previous eruptions. However, the isotopic values of early eruptive product could represent the original magma value. This result also supports the previous work of Chen et al. (1993) [Chen, C.H., DePaolo, D.J., Nakada, S., Shieh, Y.N., 1993. Relationship between eruption volume and neodymium isotopic composition at Unzen volcano. Nature 362, 831-834], that suggested the ɛNd of early or precursory eruptive products could be a qualitative indicator of the maximum size of a continuing or impending eruption.

Anatomy and ontogeny of a novel hemodynamic organ in zebrafish.

PubMed

Binelli, Erica A; Luna, Alejandra N; LeClair, Elizabeth E

2014-12-01

The zebrafish maxillary barbel can protract and retract in response to stimuli, and appears connected to a prominent blood sinus on the lateral aspect of the maxillary bone. However, the mechanism of barbel movement is not described. Using whole-mount phalloidin staining of the sinus region, we observed long filamentous actin cables, suggesting highly organized vascular smooth muscle cells, surrounding an endothelial chamber. Although the chamber is variably filled by erythrocytes in vivo, cardiac injection of fluorescent dextrans shows that it consistently contains plasma. Full-thickness confocal imaging of dextran-injected adults containing EGFP(+) endothelial cells revealed a vascular complex with three compartments, here named the distal bulb, central chamber, and accessory chamber. The early ontogeny of all three compartments was confirmed in a whole-mount series of Tg(fli1a:EGFP) juveniles. In wild type adults, the fine structure of each chamber was studied using paraffin- and plastic-section histochemistry and transmission electron microscopy. The distal bulb and central chamber have smooth muscle coats with luminally-elongated septa, forming semi-detached blood-filled lacunae. The central chamber walls and septa are extensively innervated by small, unmyelinated axons, as confirmed by immunohistochemical detection of acetylated tubulin, a component of axonal cytoplasm. The accessory chamber appears neither innervated nor muscularized, but is an endothelial cul-de-sac with a thickened elastic adventitia, suggesting an extensible fluid reservoir. We propose that we have identified a new organ in zebrafish, the maxillary barbel blood sinus, whose neurovascular specializations may contribute to zebrafish sensory biology and appendage control. © 2014 Wiley Periodicals, Inc.

Atlas-Centaur Orbiting Astronomical Observatory Shroud Test

NASA Image and Video Library

1968-04-21

Researchers at the National Aeronautics and Space Administration (NASA) Lewis Research Center conducted a series of shroud jettison tests for the second Orbiting Astronomical Observatory (OAO-2) in the Space Power Chambers during April 1968. The Orbiting Astronomical Observatory satellites were designed by Goddard Space Flight Center to study and retrieve ultraviolet data on stars and galaxies which earthbound and atmospheric telescopes could not view due to ozone absorption. The shroud jettison system was tested in the Space Power Chambers. In 1961, NASA Lewis management decided to convert its Altitude Wind Tunnel into two large test chambers and later renamed it the Space Power Chambers. The conversion, which took over two years, included removing the tunnel’s internal components and inserting bulkheads to seal off the new chambers. The larger chamber, seen here, could simulate altitudes of 100,000 feet. These chambers were used for a variety of tests on the Centaur second-stage rocket until the early 1970s. The first OAO mission in 1965 failed due to problems with the satellite. OAO-2 would be launched on an Atlas/Centaur with a modified Agena shroud. The new shroud was 18 feet longer than the normal Centaur payload shrouds. This new piece of hardware was successfully qualified during three tests at 90,000 feet altitude in the Space Power Chambers in April 1968. For the first time, x-rays were used to verify the payload clearance once the shroud was sealed. OAO-2 was launched on December 7, 1968 and proved to be an extremely successful mission.

Chamber and eddy covariance comparisons of alternate wetting and drying and continuous flood irrigation in mid-South rice

NASA Astrophysics Data System (ADS)

Reba, M. L.; Fong, B.; Adviento-Borbe, A.; Runkle, B.

2016-12-01

The subtropical humid mid-south region produces nearly 75% of US rice. Rice cultivation contributes higher amounts of GHG emissions (CO2, CH4, and N2O) due to flooded field conditions. Accurate measurements of gas fluxes are important to regional and global climate models. A comparison between eddy covariance and static vented flux chamber measurement techniques is presented. These measurements were collected in two NE Arkansas commercial rice fields in 2015 and 2016 production seasons under two irrigation treatments: Alternate Wetting and Drying (AWD) and continuous flood (CF) irrigation. AWD can reduce GHG emissions and water use compared to CF by introducing aerobic conditions that reduce methanogen activity and drained conditions decrease water loss due to seepage or evapotranspiration. N2O was measured only with vented chambers, while CO2 and CH4 were measured with both techniques. In the vented flux chamber technique, headspace gas sampling occurred at least once a week every 20 minutes for one hour of chamber closure. Gas Chromatograph equipped with ECD and FID were used to analyze gas concentrations. Eddy covariance used high frequency measurements wind and concentration measurements to determine fluxes. Chamber measurements were found to be more sensitive during seedling and early vegetative growth while eddy covariance was more sensitive after canopy closure during mid-vegetative to reproductive growth. Unlike eddy covariance which measured net CO2 exchange, flux chamber method measured only CO2 ecosystem respiration because flux measurements occurred using an opaque chamber material.

Epithelial rotation promotes the global alignment of contractile actin bundles during Drosophila egg chamber elongation

PubMed Central

Cetera, Maureen; Ramirez-San Juan, Guillermina R.; Oakes, Patrick W.; Lewellyn, Lindsay; Fairchild, Michael J.; Tanentzapf, Guy; Gardel, Margaret L.; Horne-Badovinac, Sally

2014-01-01

Tissues use numerous mechanisms to change shape during development. The Drosophila egg chamber is an organ-like structure that elongates to form an elliptical egg. During elongation the follicular epithelial cells undergo a collective migration that causes the egg chamber to rotate within its surrounding basement membrane. Rotation coincides with the formation of a “molecular corset”, in which actin bundles in the epithelium and fibrils in the basement membrane are all aligned perpendicular to the elongation axis. Here we show that rotation plays a critical role in building the actin-based component of the corset. Rotation begins shortly after egg chamber formation and requires lamellipodial protrusions at each follicle cell’s leading edge. During early stages, rotation is necessary for tissue-level actin bundle alignment, but it becomes dispensable after the basement membrane is polarized. This work highlights how collective cell migration can be used to build a polarized tissue organization for organ morphogenesis. PMID:25413675

Design and installation of a Prototype Geohazard Monitoring System near Machu Picchu, Peru

NASA Astrophysics Data System (ADS)

Bulmer, M. H.; Farquhar, T.

2010-09-01

The town of Machu Picchu, Peru, serves the >700 000 tourists visiting Machu Picchu annually. It has grown threefold in population in the past two decades. Due to the limited low-lying ground, construction is occurring on the unstable valley slopes. Slopes range from <10° on the valley floor to >70° in the surrounding mountains. The town has grown on a delta formed at the confluence of the Alcamayo, Aguas Calientes and Vilcanota Rivers. Geohazards in and around the town of particular concern are 1) large rocks falling onto the town and/or the rail line, 2) flash flooding by any one of its three rivers, and 3) mudflows and landslides. A prototype early warning system that could monitor weather, river flow and slope stability was installed along the Aguas Calientes River in 2009. This has a distributed modular construction allowing components to be installed, maintained, salvaged, and repaired by local technicians. A diverse set of candidate power, communication and sensor technologies was evaluated. Most of the technologies had never been deployed in similar terrain, altitude or weather. The successful deployment of the prototype proved that it is technically feasible to develop early warning capacity in the town.

Automated Test Case Generation for an Autopilot Requirement Prototype

NASA Technical Reports Server (NTRS)

Giannakopoulou, Dimitra; Rungta, Neha; Feary, Michael

2011-01-01

Designing safety-critical automation with robust human interaction is a difficult task that is susceptible to a number of known Human-Automation Interaction (HAI) vulnerabilities. It is therefore essential to develop automated tools that provide support both in the design and rapid evaluation of such automation. The Automation Design and Evaluation Prototyping Toolset (ADEPT) enables the rapid development of an executable specification for automation behavior and user interaction. ADEPT supports a number of analysis capabilities, thus enabling the detection of HAI vulnerabilities early in the design process, when modifications are less costly. In this paper, we advocate the introduction of a new capability to model-based prototyping tools such as ADEPT. The new capability is based on symbolic execution that allows us to automatically generate quality test suites based on the system design. Symbolic execution is used to generate both user input and test oracles user input drives the testing of the system implementation, and test oracles ensure that the system behaves as designed. We present early results in the context of a component in the Autopilot system modeled in ADEPT, and discuss the challenges of test case generation in the HAI domain.

Corneal toxicity after Ozurdex(®) migration into anterior chamber.

PubMed

Bernal, L; Estévez, B

2016-06-01

To describe a case of corneal toxicity after migration of a dexamethasone implant into the anterior chamber. A 62-year-old man with aphakia and a history of vitrectomy received a dexamethasone implant for a refractory Irvine-Gass syndrome. Thirty days later, the implant migrated into the anterior chamber causing endothelial contact with secondary corneal oedema that justified the removal of the implant without resolution of the oedema. Clinical tolerability to dislocated implant is poor in cases with pre-existing corneal oedema, and because of this, it must be removed early. In cases of aphakia and vitrectomy, the increased risk of Ozurdex(®) dislocation justifies performing a prior endothelial count. Copyright © 2016 Sociedad Española de Oftalmología. Published by Elsevier España, S.L.U. All rights reserved.

Teen motherhood and pregnancy prototypes: the role of social context in changing young African American mothers' risk images and contraceptive expectations.

PubMed

Barr, Ashley B; Simons, Ronald L; Simons, Leslie Gordon; Gibbons, Frederick X; Gerrard, Meg

2013-12-01

Despite the declining rate of teen pregnancies in the United States, academic and public health experts have expressed concern over the still relatively high rate of rapid repeat pregnancies among adolescents, particularly among minority youth. Using a sample of over 300 African American female adolescents, the current study used insights from the prototype/willingness model of adolescent risk behavior to explore this risk. More specifically, it assessed the relationship between entry into unwed motherhood during mid-to-late adolescence and changes in prototypes of unmarried pregnant teens. Further, it explored the extent to which these changing prototypes accounted for young mothers' later contraceptive expectations. We tested the possibility that social images were affected not only by personal experience (the birth of a child) but also by the family and community context in which this experience took place. The findings show that the early entrance into teen motherhood was associated with a shift toward more favorable prototypes of unwed pregnant teens, but that this was only the case for young mothers in disadvantaged contexts. Given this, prototype changes helped to explain the link between teen motherhood and contraceptive expectations only for those in disadvantaged contexts. We discuss these findings in terms of their practical and theoretical implications.

A review method for UML requirements analysis model employing system-side prototyping.

PubMed

Ogata, Shinpei; Matsuura, Saeko

2013-12-01

User interface prototyping is an effective method for users to validate the requirements defined by analysts at an early stage of a software development. However, a user interface prototype system offers weak support for the analysts to verify the consistency of the specifications about internal aspects of a system such as business logic. As the result, the inconsistency causes a lot of rework costs because the inconsistency often makes the developers impossible to actualize the system based on the specifications. For verifying such consistency, functional prototyping is an effective method for the analysts, but it needs a lot of costs and more detailed specifications. In this paper, we propose a review method so that analysts can verify the consistency among several different kinds of diagrams in UML efficiently by employing system-side prototyping without the detailed model. The system-side prototype system does not have any functions to achieve business logic, but visualizes the results of the integration among the diagrams in UML as Web pages. The usefulness of our proposal was evaluated by applying our proposal into a development of Library Management System (LMS) for a laboratory. This development was conducted by a group. As the result, our proposal was useful for discovering the serious inconsistency caused by the misunderstanding among the members of the group.

The efficacy of bromfenac ophthalmic solution 0.07% dosed once daily in achieving zero-to-trace anterior chamber cell severity following cataract surgery

PubMed Central

Silverstein, Steven M; Jackson, Mitchell A; Goldberg, Damien F; Muñoz, Mauricio

2014-01-01

Purpose To evaluate the efficacy of bromfenac ophthalmic solution 0.07% dosed once daily in achieving zero-to-trace (0–5 cells) anterior chamber cells, following cataract surgery with posterior chamber intraocular lens implantation. Methods The study designed employed two Phase III, double-masked, placebo-controlled, multicenter clinical trials of 440 subjects, randomized to either bromfenac ophthalmic solution 0.07% (n=222) or placebo (n=218). Subjects self-dosed once daily, beginning 1 day before undergoing cataract surgery with intraocular lens implantation (day –1) and again on the day of surgery (day 0) and for 14 days postoperatively. Follow-up was on days 1, 3, 8, and 15. The outcome measures included the percentage of subjects with zero-to-trace anterior chamber cells at each visit, as determined by the percentage of subjects with ≤5 anterior chamber cells, overall anterior chamber cell grades, and summed ocular inflammation score (SOIS) (combined anterior chamber cell and flare scores). Results The proportion of subjects with zero-to-trace anterior chamber cells was significantly higher in the bromfenac 0.07% group compared with the placebo group as early as day 3 (P=0.0007), continued at day 8 (P<0.0001), and through day 15 (P<0.0001). At day 15, 80.2% of subjects in the bromfenac 0.07% group achieved zero-to-trace anterior chamber cells compared with 47.2% of subjects who did so in the placebo group. The overall anterior chamber cell scores were significantly lower in the bromfenac 0.07% group compared with the placebo group at days 3, 8, and 15 (P<0.0001 at each visit). The SOIS were also significantly lower in the bromfenac group compared with the placebo group at days 3, 8, and 15 (P<0.0001 at each visit). Conclusion Bromfenac ophthalmic solution 0.07%, dosed once daily was clinically effective in achieving zero-to-trace anterior chamber cell severity after cataract surgery and was superior to placebo in all anterior chamber cell severity and inflammation outcome measures. PMID:24876763

Pressure increases, the for­mation of chromite seams, and the development of the ultramafic series in the Stillwater Complex, Montana

USGS Publications Warehouse

Lipin, Bruce R.

1993-01-01

This paper explores the hypothesis that chromite seams in the Stillwater Complex formed in response to periodic increases in total pressure in the chamber. Total pressure increased because of the positive δV of nucleation of CO2 bubbles in the melt and their subsequent rise through the magma chamber, during which the bubbles increased in volume by a factor of 4–6. By analogy with the pressure changes in the summit chambers of Kilauea and Krafla volcanoes, the maximum variation was 0⋅2–0⋅25 kbar, or 5–10% of the total pressure in the Stillwater chamber. An evaluation of the likelihood of fountaining and mixing of a new, primitive liquid that entered the chamber with the somewhat more evolved liquid already in the chamber is based upon calculations using observed and inferred velocities and flow rates of basaltic magmas moving through volcanic fissures. The calculations indicate that hot, dense magma would have oozed, rather than fountained into the chamber, and early mixing of the new and residual magmas that could have resulted in chromite crystallizing alone did not take place.Mixing was an important process in the Stillwater magma chamber, however. After the new magma in the chamber underwent ˜5% fractional crystallization, its composition, temperature, and density approached those of the overlying liquid in the chamber and the liquids then mixed. If this process occurred many times over the course of the development of the Ultramafic series, a thick column of magma with orthopyroxene on its liquidus would have been the result. Thus, the sequence of multiple injections, fractionation, and mixing with previously fractionated magma could have been the mechanism that produced the thick bronzite cumulate layer (the Bronzitite zone) above the cyclic units.

Early Rockets

NASA Image and Video Library

1958-05-15

Redstone missile No. 1002 on the launch pad at Cape Canaveral, Florida, on May 16, 1958. The Redstone ballistic missile was a high-accuracy, liquid-propelled, surface-to-surface missile developed by the Army Ballistic Missile Agency, Redstone Arsenal, in Huntsville, Alabama, under the direction of Dr. von Braun. The Redstone engine was a modified and improved version of the Air Force's Navaho cruise missile engine of the late forties. The A-series, as this would be known, utilized a cylindrical combustion chamber as compared with the bulky, spherical V-2 chamber. By 1951, the Army was moving rapidly toward the design of the Redstone missile, and production was begun in 1952. Redstone rockets became the "reliable workhorse" for America's early space program. As an example of the versatility, Redstone was utilized in the booster for Explorer 1, the first American satellite, with no major changes to the engine or missile

User engineering: A new look at system engineering

NASA Technical Reports Server (NTRS)

Mclaughlin, Larry L.

1987-01-01

User Engineering is a new System Engineering perspective responsible for defining and maintaining the user view of the system. Its elements are a process to guide the project and customer, a multidisciplinary team including hard and soft sciences, rapid prototyping tools to build user interfaces quickly and modify them frequently at low cost, and a prototyping center for involving users and designers in an iterative way. The main consideration is reducing the risk that the end user will not or cannot effectively use the system. The process begins with user analysis to produce cognitive and work style models, and task analysis to produce user work functions and scenarios. These become major drivers of the human computer interface design which is presented and reviewed as an interactive prototype by users. Feedback is rapid and productive, and user effectiveness can be measured and observed before the system is built and fielded. Requirements are derived via the prototype and baselined early to serve as an input to the architecture and software design.

Commutated automatic gain control system

NASA Technical Reports Server (NTRS)

Yost, S. R.

1982-01-01

The commutated automatic gain control (AGC) system was designed and built for the prototype Loran-C receiver is discussed. The current version of the prototype receiver, the Mini L-80, was tested initially in 1980. The receiver uses a super jolt microcomputer to control a memory aided phase loop (MAPLL). The microcomputer also controls the input/output, latitude/longitude conversion, and the recently added AGC system. The AGC control adjusts the level of each station signal, such that the early portion of each envelope rise is about at the same amplitude in the receiver envelope detector.

Digital pulse-shape analysis with a TRACE early silicon prototype

NASA Astrophysics Data System (ADS)

Mengoni, D.; Dueñas, J. A.; Assié, M.; Boiano, C.; John, P. R.; Aliaga, R. J.; Beaumel, D.; Capra, S.; Gadea, A.; Gonzáles, V.; Gottardo, A.; Grassi, L.; Herrero-Bosch, V.; Houdy, T.; Martel, I.; Parkar, V. V.; Perez-Vidal, R.; Pullia, A.; Sanchis, E.; Triossi, A.; Valiente Dobón, J. J.

2014-11-01

A highly segmented silicon-pad detector prototype has been tested to explore the performance of the digital pulse shape analysis in the discrimination of the particles reaching the silicon detector. For the first time a 200 μm thin silicon detector, grown using an ordinary floating zone technique, has been shown to exhibit a level discrimination thanks to the fine segmentation. Light-charged particles down to few MeV have been separated, including their punch-through. A coaxial HPGe detector in time coincidence has further confirmed the quality of the particle discrimination.

In-beam test of the RPC architecture foreseen to be used for the CBM-TOF inner wall

NASA Astrophysics Data System (ADS)

Petriş, M.; Bartoş, D.; Petrovici, M.; Rădulescu, L.; Simion, V.; Deppner, I.; Herrmann, N.; Simon, C.; Frühauf, J.; Kiš, M.; Loizeau, P.-A.

2018-05-01

The Time Of Flight (TOF) subsystem is one of the main detectors of the CBM experiment. The TOF wall in conjunction with Silicon Tracking System (STS) is foreseen to identify charged hadrons, i.e. pions, kaons and protons, with a full azimuthal coverage at 2.50 - 250 polar angles. A system time resolution of at least 80 ps, including all contributions, such as electronics jitter and the resolution of the time reference system, is required. Such a performance should be maintained up to a counting rate larger than 30 kHz/cm2 at the most inner region of TOF wall. Our R&D activity has been focused on the development of two-dimensional position sensitive Multi-gap Resistive Plate Counter (MRPC) prototypes for the forward region of the CBM-TOF subdetector, the most demanding zone in terms of granularity and counting rate. The in-beam tests using secondary particles produced in 30 GeV/u Pb ion collisions on a Pb target at SPS - CERN aimed to test the performance of these prototypes in conditions similar to the ones expected at SIS100 at FAIR. The performance of the prototypes is studied in conditions of exposure of the whole active area of the chamber to high multiplicity of reaction products. The results show that this type of MRPC fulfill the challenging requirements of the CBM-TOF wall. Therefore, such an architecture is recommended as basic solution for CBM-TOF inner zone.

Recent developments in PET detector technology

PubMed Central

Lewellen, Tom K

2010-01-01

Positron emission tomography (PET) is a tool for metabolic imaging that has been utilized since the earliest days of nuclear medicine. A key component of such imaging systems is the detector modules—an area of research and development with a long, rich history. Development of detectors for PET has often seen the migration of technologies, originally developed for high energy physics experiments, into prototype PET detectors. Of the many areas explored, some detector designs go on to be incorporated into prototype scanner systems and a few of these may go on to be seen in commercial scanners. There has been a steady, often very diverse development of prototype detectors, and the pace has accelerated with the increased use of PET in clinical studies (currently driven by PET/CT scanners) and the rapid proliferation of pre-clinical PET scanners for academic and commercial research applications. Most of these efforts are focused on scintillator-based detectors, although various alternatives continue to be considered. For example, wire chambers have been investigated many times over the years and more recently various solid-state devices have appeared in PET detector designs for very high spatial resolution applications. But even with scintillators, there have been a wide variety of designs and solutions investigated as developers search for solutions that offer very high spatial resolution, fast timing, high sensitivity and are yet cost effective. In this review, we will explore some of the recent developments in the quest for better PET detector technology. PMID:18695301

Innexin2 gap junctions in somatic support cells are required for cyst formation and for egg chamber formation in Drosophila.

PubMed

Mukai, Masanori; Kato, Hirotaka; Hira, Seiji; Nakamura, Katsuhiro; Kita, Hiroaki; Kobayashi, Satoru

2011-01-01

Germ cells require intimate associations with surrounding somatic cells during gametogenesis. During oogenesis, gap junctions mediate communication between germ cells and somatic support cells. However, the molecular mechanisms by which gap junctions regulate the developmental processes during oogenesis are poorly understood. We have identified a female sterile allele of innexin2 (inx2), which encodes a gap junction protein in Drosophila. In females bearing this inx2 allele, cyst formation and egg chamber formation are impaired. In wild-type germaria, Inx2 is strongly expressed in escort cells and follicle cells, both of which make close contact with germline cells. We show that inx2 function in germarial somatic cells is required for the survival of early germ cells and promotes cyst formation, probably downstream of EGFR pathway, and that inx2 function in follicle cells promotes egg chamber formation through the regulation of DE-cadherin and Bazooka (Baz) at the boundary between germ cells and follicle cells. Furthermore, genetic experiments demonstrate that inx2 interacts with the zero population growth (zpg) gene, which encodes a germline-specific gap junction protein. These results indicate a multifunctional role for Inx2 gap junctions in somatic support cells in the regulation of early germ cell survival, cyst formation and egg chamber formation. Inx2 gap junctions may mediate the transfer of nutrients and signal molecules between germ cells and somatic support cells, as well as play a role in the regulation of cell adhesion. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

A generic testbed for the design of plasma spectrometer control software with application to the THOR-CSW solar wind instrument

NASA Astrophysics Data System (ADS)

De Keyser, Johan; Lavraud, Benoit; Neefs, Eddy; Berkenbosch, Sophie; Beeckman, Bram; Maggiolo, Romain; Gamby, Emmanuel; Fedorov, Andrei; Baruah, Rituparna; Wong, King-Wah; Amoros, Carine; Mathon, Romain; Génot, Vincent; Marcucci, Federica; Brienza, Daniele

2017-04-01

Modern plasma spectrometers require intelligent software that is able to exploit their capabilities to the fullest. While the low-level control of the instrument and basic tasks such as performing the basic measurement, temperature control, and production of housekeeping data are to be done by software that is executed on an FPGA and/or processor inside the instrument, higher level tasks such as control of measurement sequences, on-board moment calculation, beam tracking decisions, and data compression, may be performed by the instrument or in the payload data processing unit. Such design decisions, as well as an assessment of the workload on the different processing components, require early prototyping. We have developed a generic simulation testbed for the design of plasma spectrometer control software that allows an early evaluation of the level of resources that is needed at each level. Early prototyping can pinpoint bottlenecks in the design allowing timely remediation. We have applied this tool to the THOR Cold Solar Wind (CSW) plasma spectrometer. Some examples illustrating the usefulness of the tool are given.

The importance of speckle tracking echocardiography in the early detection of left ventricular dysfunction in patients with polycystic ovary syndrome.

PubMed

Demirelli, Selami; Degirmenci, Husnu; Ermis, Emrah; Inci, Sinan; Nar, Gokay; Ayhan, Mehmet Emin; Fırtına, Serdar; Hamur, Hikmet; Durmaz, Senay Arikan

2015-10-19

Polycystic ovary syndrome (PCOS) is characterized by hormonal and metabolic abnormalities and is thought to increase a risk for cardiovascular diseases. In this study we use speckle tracking echocardiography (STE) to evaluate left ventricular (LV) dysfunction in the early period of the disease. We enrolled 31 patients with PCOS and 32 healthy volunteers as a control group. The participants' ages ranged between 18 and 40 years. PCOS was diagnosed according to the Rotterdam criteria. LV strain (LS) and strain rate (SR) were evaluated using apical two-chamber (2C), three-chamber (3C), and four-chamber (4C) imaging. Global LS and SR were calculated as average of three apical views. The waist-to-hip ratio, homeostasis model assessment-insulin resistance (HOMA-IR), and fasting insulin and triglyceride levels were higher in the PCOS group than in the controls (p=0.001, p=0.001, p=0.001, and p=0.005, respectively). In the PCOS group, the mitral A wave, deceleration time (DT), and isovolumetric relaxation time (IVRT) were significantly higher than in the controls (all p<0.05). The LV global longitudinal strain (GLS) and global longitudinal SR systolic (GLSRS) were significantly lower in the PCOS patient group (both p= 0.001). There were strong negative correlations between GLS and both fasting insulin (r=-0.64) and DT (r=-0.62) (both p<0.05). The study demonstrated that PCOS patients had decreased LV function using STE. Therefore, STE imaging appears to be useful for the early detection of subclinical LV dysfunction in patients with PCOS.

A One-Piece Lunar Regolith Bag Garage Prototype

NASA Technical Reports Server (NTRS)

Smithers, G. A.; Nehls, M. K.; Hovater, M. A.; Evans, S. W.; Miller, J. S.; Broughton, R. M., Jr.; Beale, D.; Kilinc-Balci, F.

2007-01-01

Shelter structures on the moon, even in early phases of exploration, should incorporate lunar materials as much as possible. This Technical Memorandum details the design and construction of a prototype for a one-piece regolith bag unpressurized garage concept and a materials testing program to investigate six candidate fabrics to learn how they might perform in the lunar environment. The conceptualization was that a lightweight fabric form be launched from Earth and landed on the lunar surface to be robotically filled with raw lunar regolith. Regolith bag fabric candidates included: Vectran(TM), Nextel(TM), Gore PTFE Fabric(TM), Zylon(TM), Twaron(TM), and Nomex(TM). Tensile (including post radiation exposure), fold, abrasion, and hypervelocity impact testing were performed under ambient conditions, and also performed under cold and elevated temperatures. In some cases, Johnson Space Center lunar simulant (JSC-1) was used in conjunction with testing. A series of preliminary structures was constructed during final prototype design based on the principles of the classic masonry arch. The prototype was constructed of Kevlar(TM) and filled with vermiculite. The structure is free-standing, but has not yet been load tested. Future plans would be to construct higher fidelity prototypes and to conduct appropriate tests of the structure.

Pulsed fusion space propulsion: Computational Magneto-Hydro Dynamics of a multi-coil parabolic reaction chamber

NASA Astrophysics Data System (ADS)

Romanelli, Gherardo; Mignone, Andrea; Cervone, Angelo

2017-10-01

Pulsed fusion propulsion might finally revolutionise manned space exploration by providing an affordable and relatively fast access to interplanetary destinations. However, such systems are still in an early development phase and one of the key areas requiring further investigations is the operation of the magnetic nozzle, the device meant to exploit the fusion energy and generate thrust. One of the last pulsed fusion magnetic nozzle design is the so called multi-coil parabolic reaction chamber: the reaction is thereby ignited at the focus of an open parabolic chamber, enclosed by a series of coaxial superconducting coils that apply a magnetic field. The field, beside confining the reaction and preventing any contact between hot fusion plasma and chamber structure, is also meant to reflect the explosion and push plasma out of the rocket. Reflection is attained thanks to electric currents induced in conductive skin layers that cover each of the coils, the change of plasma axial momentum generates thrust in reaction. This working principle has yet to be extensively verified and computational Magneto-Hydro Dynamics (MHD) is a viable option to achieve that. This work is one of the first detailed ideal-MHD analysis of a multi-coil parabolic reaction chamber of this kind and has been completed employing PLUTO, a freely distributed computational code developed at the Physics Department of the University of Turin. The results are thus a preliminary verification of the chamber's performance. Nonetheless, plasma leakage through the chamber structure has been highlighted. Therefore, further investigations are required to validate the chamber design. Implementing a more accurate physical model (e.g. Hall-MHD or relativistic-MHD) is thus mandatory, and PLUTO shows the capabilities to achieve that.

Inside storm window

NASA Astrophysics Data System (ADS)

Kaplan, J. I.

1980-11-01

The work effort to design, build, install, and evaluate an inside storm window (ISW) is presented. The ISW, made of two separated layers of mylar (like a thermopane window) which, when not in use can be rolled up in a shade, is described. The work effort included: development of a prototype model; the development of production facilities to turn out a small number (50) of ISW's; the production of the windows; the installation of the windows into buildings; the building of a test chamber to determine the R value of the ISW and the subsequent determination of the R value; and a survey to determine how the residents of the homes in which ISW's were installed felt about the windows.

A Refrigerated Web Camera for Photogrammetric Video Measurement inside Biomass Boilers and Combustion Analysis

PubMed Central

Porteiro, Jacobo; Riveiro, Belén; Granada, Enrique; Armesto, Julia; Eguía, Pablo; Collazo, Joaquín

2011-01-01

This paper describes a prototype instrumentation system for photogrammetric measuring of bed and ash layers, as well as for flying particle detection and pursuit using a single device (CCD) web camera. The system was designed to obtain images of the combustion process in the interior of a domestic boiler. It includes a cooling system, needed because of the high temperatures in the combustion chamber of the boiler. The cooling system was designed using CFD simulations to ensure effectiveness. This method allows more complete and real-time monitoring of the combustion process taking place inside a boiler. The information gained from this system may facilitate the optimisation of boiler processes. PMID:22319349

Large Area Coverage of a TPC Endcap with GridPix Detectors

NASA Astrophysics Data System (ADS)

Kaminski, Jochen

2018-02-01

The Large Prototype TPC at DESY, Hamburg, was built by the LCTPC collaboration as a testbed for new readout technologies of Time Projection Chambers. Up to seven modules of about 400 cm2 each can be placed in the endcap. Three of these modules were equipped with a total of 160 GridPix detectors. This is a combination of a highly pixelated readout ASIC and a Micromegas built on top. GridPix detectors have a very high efficiency of detecting primary electrons, which leads to excellent spatial and energy resolutions. For the first time a large number of GridPix detectors has been operated and long segments of tracks have been recorded with excellent precision.

Fabrication and assembly of a superconducting undulator for the advanced photon source

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hasse, Quentin; Fuerst, J. D.; Ivanyushenkov, Y.

2014-01-29

A prototype superconducting undulator magnet (SCU0) has been built at the Advanced Photon Source (APS) of Argonne National Laboratory (ANL) and has successfully completed both cryogenic performance and magnetic measurement test programs. The SCU0 closed loop, zero-boil-off cryogenic system incorporates high temperature superconducting (HTS) current leads, cryocoolers, a LHe reservoir supplying dual magnetic cores, and an integrated cooled beam chamber. This system presented numerous challenges in the design, fabrication, and assembly of the device. Aspects of this R and D relating to both the cryogenic and overall assembly of the device are presented here. The SCU0 magnet has been installedmore » in the APS storage ring.« less

Hormonal regulation of wheat growth during hydroponic culture

NASA Technical Reports Server (NTRS)

Wetherell, Donald

1988-01-01

Hormonal control of root growth has been explored as one means to alleviate the crowding of plant root systems experienced in prototype hydroponic biomass production chambers being developed by the CELSS Breadboard Project. Four plant hormones, or their chemical analogs, which have been reported to selectively inhibit root growth, were tested by adding them to the nutrient solutions on day 10 of a 25 day growth test using spring wheat in hydroponic cultures. Growth and morphological changes is both shoot and root systems were evaluated. In no case was it possible to inhibit root growth without a comparable inhibition of shoot growth. It was concluded that this approach is unlikely to prove useful for wheat.

A refrigerated web camera for photogrammetric video measurement inside biomass boilers and combustion analysis.

PubMed

Porteiro, Jacobo; Riveiro, Belén; Granada, Enrique; Armesto, Julia; Eguía, Pablo; Collazo, Joaquín

2011-01-01

This paper describes a prototype instrumentation system for photogrammetric measuring of bed and ash layers, as well as for flying particle detection and pursuit using a single device (CCD) web camera. The system was designed to obtain images of the combustion process in the interior of a domestic boiler. It includes a cooling system, needed because of the high temperatures in the combustion chamber of the boiler. The cooling system was designed using CFD simulations to ensure effectiveness. This method allows more complete and real-time monitoring of the combustion process taking place inside a boiler. The information gained from this system may facilitate the optimisation of boiler processes.

Electromagnetic stirring in a microbioreactor with non-conventional chamber morphology and implementation of multiplexed mixing.

PubMed

Tan, Christabel Kl; Davies, Matthew J; McCluskey, Daniel K; Munro, Ian R; Nweke, Mauryn C; Tracey, Mark C; Szita, Nicolas

2015-10-01

Microbioreactors have emerged as novel tools for early bioprocess development. Mixing lies at the heart of bioreactor operation (at all scales). The successful implementation of micro-stirring methods is thus central to the further advancement of microbioreactor technology. The aim of this study was to develop a micro-stirring method that aids robust microbioreactor operation and facilitates cost-effective parallelization. A microbioreactor was developed with a novel micro-stirring method involving the movement of a magnetic bead by sequenced activation of a ring of electromagnets. The micro-stirring method offers flexibility in chamber designs, and mixing is demonstrated in cylindrical, diamond and triangular shaped reactor chambers. Mixing was analyzed for different electromagnet on/off sequences; mixing times of 4.5 s, 2.9 s, and 2.5 s were achieved for cylindrical, diamond and triangular shaped chambers, respectively. Ease of micro-bubble free priming, a typical challenge of cylindrical shaped microbioreactor chambers, was obtained with a diamond-shaped chamber. Consistent mixing behavior was observed between the constituent reactors in a duplex system. A novel stirring method using electromagnetic actuation offering rapid mixing and easy integration with microbioreactors was characterized. The design flexibility gained enables fabrication of chambers suitable for microfluidic operation, and a duplex demonstrator highlights potential for cost-effective parallelization. Combined with a previously published cassette-like fabrication of microbioreactors, these advances will facilitate the development of robust and parallelized microbioreactors. © 2015 The Authors. Journal of Chemical Technology & Biotechnology published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.

A cylindrical salad growth facility with a light-emitting diodes unit as a component for biological life support system for space crews

NASA Astrophysics Data System (ADS)

Erokhin, A. N.; Berkovich, Yu. A.; Smolianina, S. O.; Krivobok, N. M.; Agureev, A. N.; Kalandarov, S. K.

2006-01-01

Efficiency of salad production under light-emitting diodes was tested with a prototype space plant growth facility "Phytocycle SD" with a 10-step crop conveyer. The system has a plant chamber in the form of a spiral cylinder. The planting unit inside the chamber is built of 10 root modules which provide a co-axial planting cylinder that rotates relative to the leaf chamber. Twelve panels of the lighting unit on the internal surfaces of the spiral cylinder carry 438 red (660 nm) and 88 blue (470 nm) light-emitting diodes producing average PPF equal 360 μmol m -2 s -1 4 cm below the light source, and 3 panels producing PPF equal 190 μmol m -2 s -1 at the initial steps of the plant conveyer. The system requires 0.44 kW and provides a plant chamber volume of 0.19 m 3, with 0.86 m 2 illuminated crop area. Productive efficiency of the facility was studied in a series of laboratory experiments with celery cabbage ( Brassica pekinensis) ( Lour) ( Rupr.) grown in the conveyer with a one-step period of 3 days. The crop grew in a fiber ion-exchange mineral-rich soil BIONA V3 under the 24-h light. Maximal productivity of the ripe (30-day-old) plants reached 700 g of the fresh edible biomass from one root module. There was a 30% greater biomass production and 3-5 times greater specific productivity per unit of expenditure of consumable resources over plants grown in a flat planting. This improved production was due to the extension of illuminated crop area for the final conveyor steps and concentration of photon flux toward center axis of cylindrical growth chamber. Biomass contents of ascorbic acid and carotene gathered from one root module per day ranged from 250 to 300 mg and 30 to 40 mg respectively. With this productivity, celery cabbage raised in "Phytocycle SD" potentially can satisfy the daily demands in vitamin C, vitamin A for a crew of three. Wider nutritional needs can be satisfied by planting mixed salad crops.

Simulated NASA Satellite Data Products for the NOAA Integrated Coral Reef Observation Network/Coral Reef Early Warning System

NASA Technical Reports Server (NTRS)

Estep, Leland; Spruce, Joseph P.

2007-01-01

This RPC (Rapid Prototyping Capability) experiment will demonstrate the use of VIIRS (Visible/Infrared Imager/Radiometer Suite) and LDCM (Landsat Data Continuity Mission) sensor data as significant input to the NOAA (National Oceanic and Atmospheric Administration) ICON/ CREWS (Integrated Coral Reef Observation System/Coral Reef Early Warning System). The project affects the Coastal Management Program Element of the Applied Sciences Program.

Long-Term Growth of Moss in Microfluidic Devices Enables Subcellular Studies in Development.

PubMed

Bascom, Carlisle S; Wu, Shu-Zon; Nelson, Katherine; Oakey, John; Bezanilla, Magdalena

2016-09-01

Key developmental processes that occur on the subcellular and cellular level or occur in occluded tissues are difficult to access, let alone image and analyze. Recently, culturing living samples within polydimethylsiloxane (PDMS) microfluidic devices has facilitated the study of hard-to-reach developmental events. Here, we show that an early diverging land plant, Physcomitrella patens, can be continuously cultured within PDMS microfluidic chambers. Because the PDMS chambers are bonded to a coverslip, it is possible to image P. patens development at high resolution over long time periods. Using PDMS chambers, we report that wild-type protonemal tissue grows at the same rate as previously reported for growth on solid medium. Using long-term imaging, we highlight key developmental events, demonstrate compatibility with high-resolution confocal microscopy, and obtain growth rates for a slow-growing mutant. By coupling the powerful genetic tools available to P. patens with long-term growth and imaging provided by PDMS microfluidic chambers, we demonstrate the capability to study cellular and subcellular developmental events in plants directly and in real time. © 2016 American Society of Plant Biologists. All rights reserved.

Development of a compact 30 T magnetic field system for OMEGA

NASA Astrophysics Data System (ADS)

Fiksel, G.; Backhus, R.; McNally, P.; Viges, E.; Villalta, M.; Jacobs-Perkins, D.; Betti, R.

2017-10-01

Aiming at conducting studies of magnetized high-energy density plasmas in a high magnetic field, we are developing a compact system capable of creating a pulsed magnetic field of about 30T in a volume of several cubic centimeters. The system prototype will be tested at the University of Michigan and will be adopted afterwards for use at the OMEGA facility of the Laboratory for Laser Energetics (LLE) of the University of Rochester, NY. The system consists of a pulsed power supply situated outside of the Omega vacuum chamber and a magnetic coil inserted into the chamber with a diagnostic inserter. The power supply is based on a 50 μF/20kV storage capacitor and is capable of driving a pulse of current of up to 50kA through the coil. The power supply is connected with the coil via a low-inductive chain of power cables and a strip transmission line. The system electrical, magnetic, and thermal analysis will be presented along with the results of initial testing. This work is supported in part through a DOE-OFES award DE-SC0016258 and a University of Michigan research Grant U051442.

A micro-machined piezoelectric flexural-mode hydrophone with air backing: a hydrostatic pressure-balancing mechanism for integrity preservation.

PubMed

Choi, Sungjoon; Lee, Haksue; Moon, Wonkyu

2010-09-01

Although an air-backed thin plate is an effective sound receiver structure, it is easily damaged via pressure unbalance caused by external hydrostatic pressure. To overcome this difficulty, a simple pressure-balancing module is proposed. Despite its small size and relative simplicity, with proper design and operation, micro-channel structure provides a solution to the pressure-balancing problem. If the channel size is sufficiently small, the gas-liquid interface may move back and forth without breach by the hydrostatic pressure since the surface tension can retain the interface surface continuously. One input port of the device is opened to an intermediate liquid, while the other port is connected to the air-backing chamber. As the hydrostatic pressure increases, the liquid in the micro-channel compresses the air, and the pressure in the backing chamber is then equalized to match the external hydrostatic pressure. To validate the performance of the proposed mechanism, a micro-channel prototype is designed and integrated with the piezoelectric micro-machined flexural sensor developed in our previous work. The working principle of the mechanism is experimentally verified. In addition, the effect of hydrostatic pressure on receiving sensitivity is evaluated and compared with predicted behavior.

Accuracy of a new partial coherence interferometry analyser for biometric measurements.

PubMed

Holzer, M P; Mamusa, M; Auffarth, G U

2009-06-01

Precise biometry is an essential preoperative measurement for refractive surgery as well as cataract surgery. A new device based on partial coherence interferometry technology was tested and evaluated for accuracy of measurements. In a prospective study 200 eyes of 100 healthy phakic volunteers were examined with a functional prototype of the new ALLEGRO BioGraph (Wavelight AG)/LENSTAR LS 900 (Haag Streit AG) biometer and with the IOLMaster V.5 (Carl Zeiss Meditec AG). As recommended by the manufacturers, repeated measurements were performed with both devices and the results compared using Spearman correlation calculations (WinSTAT). Spearman correlation showed high correlations for axial length and keratometry measurements between the two devices tested. Anterior chamber depth, however, had a lower correlation between the two biometry devices. In addition, the mean values of the anterior chamber depth differed (IOLMaster 3.48 (SD 0.42) mm versus BioGraph/LENSTAR 3.64 (SD 0.26) mm); however, this difference was not statistically different (p>0.05, t test). The new biometer provided results that correlated very well with those of the IOLMaster. The ALLEGRO BioGraph/LENSTAR LS 900 is a precise device containing additional features that will be helpful tools for any cataract or refractive surgeon.

The Growth of Protein Crystals Using McDUCK

NASA Technical Reports Server (NTRS)

Ewing, Felicia; Wilson, Lori; Nadarajah, Arunan; Pusey, Marc

1998-01-01

Most of the current microgravity crystal growth hardware is optimized to produce crystals within the limited time available on orbit. This often results in the actual nucleation and growth process being rushed or the system not coming to equilibrium within the limited time available. Longer duration hardware exists, but one cannot readily pick out crystals grown early versus those which nucleated and grew more slowly. We have devised a long duration apparatus, the Multi-chamber Dialysis Unit for Crystallization Kinetics, or McDUCK. This apparatus-is a series of protein chambers, stacked upon a precipitant reservoir chamber. All chambers are separated by a dialysis membrane, which serves to pass small molecules while retaining the protein. The volume of the Precipitant chamber is equal to the sum of the volumes of the protein chamber. In operation, the appropriate chambers are filled with precipitant solution or protein solution, and the McDUCK is placed standing upright, with the precipitant chamber on the bottom. The precipitant diffuses upwards over time, with the time to reach equilibration a function of the diffusivity of the precipitant and the overall length of the diffusion pathway. Typical equilibration times are approximately 2-4 months, and one can readily separate rapid from slow nucleation and growth crystals. An advantage on Earth is that the vertical precipitant concentration gradient dominates that of the solute, thus dampening out solute density gradient driven convective flows. However, large Earth-grown crystals have so far tended to be more two dimensional. Preliminary X-ray diffraction analysis of lysozyme crystals grown in McDUCK have indicated that the best, and largest, come from the middle chambers, suggesting that there is an optimal growth rate. Further, the improvements in diffraction resolution have been better signal to noise ratios in the low resolution data, not an increase in resolution overall. Due to the persistently large crystals grown we are currently proposing McDUCK for the growth of macromolecule crystals for use in neutron diffraction studies.

Early road location : the key to discovering historic resources?.

DOT National Transportation Integrated Search

1980-01-01

The paper describes a unique methodology used in surveying and documenting architecture along eighteenth century road systems in Virginia which could be used as a prototype in other areas. In the method described the historian geographer, and archite...

Self-Organization in High-Density Bacterial Colonies: Efficient Crowd Control

PubMed Central

Campbell, Kyle; Melke, Pontus; Williams, Joshua W; Jedynak, Bruno; Stevens, Ann M; Groisman, Alex; Levchenko, Andre

2007-01-01

Colonies of bacterial cells can display complex collective dynamics, frequently culminating in the formation of biofilms and other ordered super-structures. Recent studies suggest that to cope with local environmental challenges, bacterial cells can actively seek out small chambers or cavities and assemble there, engaging in quorum sensing behavior. By using a novel microfluidic device, we showed that within chambers of distinct shapes and sizes allowing continuous cell escape, bacterial colonies can gradually self-organize. The directions of orientation of cells, their growth, and collective motion are mutually correlated and dictated by the chamber walls and locations of chamber exits. The ultimate highly organized steady state is conducive to a more-organized escape of cells from the chambers and increased access of nutrients into and evacuation of waste out of the colonies. Using a computational model, we suggest that the lengths of the cells might be optimized to maximize self-organization while minimizing the potential for stampede-like exit blockage. The self-organization described here may be crucial for the early stage of the organization of high-density bacterial colonies populating small, physically confined growth niches. It suggests that this phenomenon can play a critical role in bacterial biofilm initiation and development of other complex multicellular bacterial super-structures, including those implicated in infectious diseases. PMID:18044986

Preliminary Results on New Prototypes of Precision Rh-0.5at%Fe Resistance Thermometers of Chinese Production

NASA Astrophysics Data System (ADS)

Pavese, F.; Szmyrka-Grzebyk, A.; Lipinski, L.; Manuszkiewicz, H.; Qiu, Ping; Zhang, Jin Tao; Lin, Peng; Li, Xing Wei

2008-02-01

Given the practical impossibility of obtaining new precision Rh-0.5at%Fe resistance thermometers in recent years, the possible re-starting of the production of such thermometers in Yunnan (China) was explored by Istituto Nazionale di Ricerca Metrologica (INRIM). Ten prototypes of the new production were made available in early 2006. The paper reports the preliminary data from the testing performed to date on these prototypes at National Institute of Metrology (NIM) and Instytut Niskich Temperatur i Badan Strukturalnych (INTiBS). Although a problem with the alloy composition was detected, the reproducibility results on thermal cycling are very encouraging. Resistance-temperature ( R- T) characteristics below 30 K, though not identical with those of similar thermometers formerly available from Tinsley and VNIIFTRI, are still suitable for accurate metrology.

Prototype test article verification of the Space Station Freedom active thermal control system microgravity performance

NASA Technical Reports Server (NTRS)

Chen, I. Y.; Ungar, E. K.; Lee, D. Y.; Beckstrom, P. S.

1993-01-01

To verify the on-orbit operation of the Space Station Freedom (SSF) two-phase external Active Thermal Control System (ATCS), a test and verification program will be performed prior to flight. The first system level test of the ATCS is the Prototype Test Article (PTA) test that will be performed in early 1994. All ATCS loops will be represented by prototypical components and the line sizes and lengths will be representative of the flight system. In this paper, the SSF ATCS and a portion of its verification process are described. The PTA design and the analytical methods that were used to quantify the gravity effects on PTA operation are detailed. Finally, the gravity effects are listed, and the applicability of the 1-g PTA test results to the validation of on-orbit ATCS operation is discussed.

Simulation in a dynamic prototyping environment: Petri nets or rules?

NASA Technical Reports Server (NTRS)

Moore, Loretta A.; Price, Shannon W.; Hale, Joseph P.

1994-01-01

An evaluation of a prototyped user interface is best supported by a simulation of the system. A simulation allows for dynamic evaluation of the interface rather than just a static evaluation of the screen's appearance. This allows potential users to evaluate both the look (in terms of the screen layout, color, objects, etc.) and feel (in terms of operations and actions which need to be performed) of a system's interface. Because of the need to provide dynamic evaluation of an interface, there must be support for producing active simulations. The high-fidelity training simulators are normally delivered too late to be effectively used in prototyping the displays. Therefore, it is important to build a low fidelity simulator, so that the iterative cycle of refining the human computer interface based upon a user's interactions can proceed early in software development.

The use of an automated flight test management system in the development of a rapid-prototyping flight research facility

NASA Technical Reports Server (NTRS)

Duke, Eugene L.; Hewett, Marle D.; Brumbaugh, Randal W.; Tartt, David M.; Antoniewicz, Robert F.; Agarwal, Arvind K.

1988-01-01

An automated flight test management system (ATMS) and its use to develop a rapid-prototyping flight research facility for artificial intelligence (AI) based flight systems concepts are described. The ATMS provides a flight test engineer with a set of tools that assist in flight planning and simulation. This system will be capable of controlling an aircraft during the flight test by performing closed-loop guidance functions, range management, and maneuver-quality monitoring. The rapid-prototyping flight research facility is being developed at the Dryden Flight Research Facility of the NASA Ames Research Center (Ames-Dryden) to provide early flight assessment of emerging AI technology. The facility is being developed as one element of the aircraft automation program which focuses on the qualification and validation of embedded real-time AI-based systems.

Integration of the Reconfigurable Self-Healing eDNA Architecture in an Embedded System

NASA Technical Reports Server (NTRS)

Boesen, Michael Reibel; Keymeulen, Didier; Madsen, Jan; Lu, Thomas; Chao, Tien-Hsin

2011-01-01

In this work we describe the first real world case study for the self-healing eDNA (electronic DNA) architecture by implementing the control and data processing of a Fourier Transform Spectrometer (FTS) on an eDNA prototype. For this purpose the eDNA prototype has been ported from a Xilinx Virtex 5 FPGA to an embedded system consisting of a PowerPC and a Xilinx Virtex 5 FPGA. The FTS instrument features a novel liquid crystal waveguide, which consequently eliminates all moving parts from the instrument. The addition of the eDNA architecture to do the control and data processing has resulted in a highly fault-tolerant FTS instrument. The case study has shown that the early stage prototype of the autonomous self-healing eDNA architecture is expensive in terms of execution time.

Simulation in a dynamic prototyping environment: Petri nets or rules?

NASA Technical Reports Server (NTRS)

Moore, Loretta A.; Price, Shannon; Hale, Joseph P.

1994-01-01

An evaluation of a prototyped user interface is best supported by a simulation of the system. A simulation allows for dynamic evaluation of the interface rather than just a static evaluation of the screen's appearance. This allows potential users to evaluate both the look (in terms of the screen layout, color, objects, etc.) and feel (in terms of operations and actions which need to be performed) of a system's interface. Because of the need to provide dynamic evaluation of an interface, there must be support for producing active simulations. The high-fidelity training simulators are delivered too late to be effectively used in prototyping the displays. Therefore, it is important to build a low fidelity simulator, so that the iterative cycle of refining the human computer interface based upon a user's interactions can proceed early in software development.

RED Alert – Early warning or detection of global re-emerging infectious disease (RED)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Deshpande, Alina

This is the PDF of a presentation for a webinar given by Los Alamos National Laboratory (LANL) on the early warning or detection of global re-emerging infectious disease (RED). First, there is an overview of LANL biosurveillance tools. Then, information is given about RED Alert. Next, a demonstration is given of a component prototype. RED Alert is an analysis tool that can provide early warning or detection of the re-emergence of an infectious disease at the global level, but through a local lens.

No Heat Spray Drying Technology

DOE Office of Scientific and Technical Information (OSTI.GOV)

Beetz, Charles

No Heat Spray Drying Technology. ZoomEssence has developed our Zooming™ spray drying technology that atomizes liquids to powders at ambient temperature. The process of drying a liquid into a powder form has been traditionally achieved by mixing a heated gas with an atomized (sprayed) fluid within a vessel (drying chamber) causing the solvent to evaporate. The predominant spray drying process in use today employs air heated up to 400° Fahrenheit to dry an atomized liquid into a powder. Exposing sensitive, volatile liquid ingredients to high temperature causes molecular degradation that negatively impacts solubility, stability and profile of the powder. Inmore » short, heat is detrimental to many liquid ingredients. The completed award focused on several areas in order to advance the prototype dryer to a commercial scale integrated pilot system. Prior to the award, ZoomEssence had developed a prototype ‘no-heat’ dryer that firmly established the feasibility of the Zooming™ process. The award focused on three primary areas to improve the technology: (1) improved ability to formulate emulsions for specific flavor groups and improved understanding of the relationship of emulsion properties to final dry particle properties, (2) a new production atomizer, and (3) a dryer controls system.« less

(abstract) A Miniature, High-Sensitivity, Electron-Tunneling Accelerometer

NASA Technical Reports Server (NTRS)

Gabrielson, Thomas B.; Rockstad, Howard K.; Tang, Tony K.

1994-01-01

A prototype low-noise accelerometer has been fabricated with an electron-tunneling transducer. By measuring the tunneling current between an electrode on the proof mass and a feedback-controlled monitor electrode, very small accelerations can be detected with high responsivity. This particular prototype (10x10x1.5 mm) was designed for underwater acoustic measurement from a few hertz to 1 kHz. The measured responsivity below the fundamental device resonance at 100 Hz is roughly 1500 volts per m/s(sup 2) with a measured noise spectral density of 10(sup -6) m/s(sup 2) per root hertz or less between 30 and 300 Hz. The noise floor is controlled primarily by 1/f noise in the tunneling current although the noise floor reaches the theoretical molecular-agitation limit at 100 hertz. The responsivity and directivity of the device were measured in a standard gradient-hydrophone calibrator; the noise floor was determined in a vacuum-ionization chamber assembled from commercial off-the-shelf components; and the detailed dynamics of the proof-mass motion were examined using a heterodyne laser interferometer that was scanned across the surface and synchronously detected with respect to the excitation.

A hybrid electronically scanned pressure module for cryogenic environments

NASA Technical Reports Server (NTRS)

Chapman, J. J.; Hopson, P., Jr.; Kruse, N.

1995-01-01

Pressure is one of the most important parameters measured when testing models in wind tunnels. For models tested in the cryogenic environment of the National Transonic Facility at NASA Langley Research Center, the technique of utilizing commercially available multichannel pressure modules inside the models is difficult due to the small internal volume of the models and the requirement of keeping the pressure transducer modules within an acceptable temperature range well above the -173 degrees C tunnel temperature. A prototype multichannel pressure transducer module has been designed and fabricated with stable, repeatable sensors and materials optimized for reliable performance in the cryogenic environment. The module has 16 single crystal silicon piezoresistive pressure sensors electrostatically bonded to a metalized Pyrex substrate for sensing the wind tunnel model pressures. An integral temperature sensor mounted on each silicon micromachined pressure sensor senses real-time temperature fluctuations to within 0.1 degrees C to correct for thermally induced non-random sensor drift. The data presented here are from a prototype sensor module tested in the 0.3 M cryogenic tunnel and thermal equilibrium conditions in an environmental chamber which approximates the thermal environment (-173 degrees C to +60 degrees C) of the National Transonic Facility.

Back-end and interface implementation of the STS-XYTER2 prototype ASIC for the CBM experiment

NASA Astrophysics Data System (ADS)

Kasinski, K.; Szczygiel, R.; Zabolotny, W.

2016-11-01

Each front-end readout ASIC for the High-Energy Physics experiments requires robust and effective hit data streaming and control mechanism. A new STS-XYTER2 full-size prototype chip for the Silicon Tracking System and Muon Chamber detectors in the Compressed Baryonic Matter experiment at Facility for Antiproton and Ion Research (FAIR, Germany) is a 128-channel time and amplitude measuring solution for silicon microstrip and gas detectors. It operates at 250 kHit/s/channel hit rate, each hit producing 27 bits of information (5-bit amplitude, 14-bit timestamp, position and diagnostics data). The chip back-end implements fast front-end channel read-out, timestamp-wise hit sorting, and data streaming via a scalable interface implementing the dedicated protocol (STS-HCTSP) for chip control and hit transfer with data bandwidth from 9.7 MHit/s up to 47 MHit/s. It also includes multiple options for link diagnostics, failure detection, and throttling features. The back-end is designed to operate with the data acquisition architecture based on the CERN GBTx transceivers. This paper presents the details of the back-end and interface design and its implementation in the UMC 180 nm CMOS process.

Testing of the Geoscience Laser Altimeter System (GLAS) Prototype Loop Heat Pipe

NASA Technical Reports Server (NTRS)

Douglas, Donya; Ku, Jentung; Kaya, Tarik

1998-01-01

This paper describes the testing of the prototype loop heat pipe (LHP) for the Geoscience Laser Altimeter System (GLAS). The primary objective of the test program was to verify the loop's heat transport and temperature control capabilities under conditions pertinent to GLAS applications. Specifically, the LHP had to demonstrate a heat transport capability of 100 W, with the operating temperature maintained within +/-2K while the condenser sink was subjected to a temperature change between 273K and 283K. Test results showed that this loop heat pipe was more than capable of transporting the required heat load and that the operating temperature could be maintained within +/-2K. However, this particular integrated evaporator-compensation chamber design resulted in an exchange of energy between the two that affected the overall operation of the system. One effect was the high temperature the LHP was required to reach before nucleation would begin due to inability to control liquid distribution during ground testing. Another effect was that the loop had a low power start-up limitation of approximately 25 W. These Issues may be a concern for other applications, although it is not expected that they will cause problems for GLAS under micro-gravity conditions.

Performance of a Micro-Strip Gas Chamber for event wise, high rate thermal neutron detection with accurate 2D position determination

NASA Astrophysics Data System (ADS)

Mindur, B.; Alimov, S.; Fiutowski, T.; Schulz, C.; Wilpert, T.

2014-12-01

A two-dimensional (2D) position sensitive detector for neutron scattering applications based on low-pressure gas amplification and micro-strip technology was built and tested with an innovative readout electronics and data acquisition system. This detector contains a thin solid neutron converter and was developed for time- and thus wavelength-resolved neutron detection in single-event counting mode, which improves the image contrast in comparison with integrating detectors. The prototype detector of a Micro-Strip Gas Chamber (MSGC) was built with a solid natGd/CsI thermal neutron converter for spatial resolutions of about 100 μm and counting rates up to 107 neutrons/s. For attaining very high spatial resolutions and counting rates via micro-strip readout with centre-of-gravity evaluation of the signal amplitude distributions, a fast, channel-wise, self-triggering ASIC was developed. The front-end chips (MSGCROCs), which are very first signal processing components, are read out into powerful ADC-FPGA boards for on-line data processing and thereafter via Gigabit Ethernet link into the data receiving PC. The workstation PC is controlled by a modular, high performance dedicated software suite. Such a fast and accurate system is crucial for efficient radiography/tomography, diffraction or imaging applications based on high flux thermal neutron beam. In this paper a brief description of the detector concept with its operation principles, readout electronics requirements and design together with the signals processing stages performed in hardware and software are presented. In more detail the neutron test beam conditions and measurement results are reported. The focus of this paper is on the system integration, two dimensional spatial resolution, the time resolution of the readout system and the imaging capabilities of the overall setup. The detection efficiency of the detector prototype is estimated as well.

The current status of fluoride salt cooled high temperature reactor (FHR) technology and its overlap with HIF target chamber concepts

NASA Astrophysics Data System (ADS)

Scarlat, Raluca O.; Peterson, Per F.

2014-01-01

The fluoride salt cooled high temperature reactor (FHR) is a class of fission reactor designs that use liquid fluoride salt coolant, TRISO coated particle fuel, and graphite moderator. Heavy ion fusion (HIF) can likewise make use of liquid fluoride salts, to create thick or thin liquid layers to protect structures in the target chamber from ablation by target X-rays and damage from fusion neutron irradiation. This presentation summarizes ongoing work in support of design development and safety analysis of FHR systems. Development work for fluoride salt systems with application to both FHR and HIF includes thermal-hydraulic modeling and experimentation, salt chemistry control, tritium management, salt corrosion of metallic alloys, and development of major components (e.g., pumps, heat exchangers) and gas-Brayton cycle power conversion systems. In support of FHR development, a thermal-hydraulic experimental test bay for separate effects (SETs) and integral effect tests (IETs) was built at UC Berkeley, and a second IET facility is under design. The experiments investigate heat transfer and fluid dynamics and they make use of oils as simulant fluids at reduced scale, temperature, and power of the prototypical salt-cooled system. With direct application to HIF, vortex tube flow was investigated in scaled experiments with mineral oil. Liquid jets response to impulse loading was likewise studied using water as a simulant fluid. A set of four workshops engaging industry and national laboratory experts were completed in 2012, with the goal of developing a technology pathway to the design and licensing of a commercial FHR. The pathway will include experimental and modeling efforts at universities and national laboratories, requirements for a component test facility for reliability testing of fluoride salt equipment at prototypical conditions, requirements for an FHR test reactor, and development of a pre-conceptual design for a commercial reactor.

TH-C-19A-01: Analytic Design Method to Make a 2D Planar, Segmented Ion Chamber Water-Equivalent for Proton Dose Measurements

DOE Office of Scientific and Technical Information (OSTI.GOV)

Harris, W; Hollebeek, R; Teo, B

2014-06-15

Purpose: Quality Assurance (QA) measurements of proton therapy fields must accurately measure steep longitudinal dose gradients as well as characterize the dose distribution laterally. Currently, available devices for two-dimensional field measurements perturb the dose distribution such that routine QA measurements performed at multiple depths require multiple field deliveries and are time consuming. Methods: A design procedure for a two-dimensional detector array is introduced whereby the proton energy loss and scatter are adjusted so that the downstream dose distribution is maintained to be equivalent to that which would occur in uniform water. Starting with the design for an existing, functional two-dimensionalmore » segmented ion chamber prototype, a compensating material is introduced downstream of the detector to simultaneously equate the energy loss and lateral scatter in the detector assembly to the values in water. An analytic formalism and procedure is demonstrated to calculate the properties of the compensating material in the general case of multiple layers of arbitrary material. The resulting design is validated with Monte Carlo simulations. Results: With respect to the specific prototype design considered, the results indicate that a graphite compensating layer of the proper dimensions can yield proton beam range perturbation less than 0.1mm and beam sigma perturbation less than 2% across the energy range of therapeutic proton beams. Conclusion: We have shown that, for a 2D gas-filled detector array, a graphite-compensating layer can balance the energy loss and multiple Coulomb scattering relative to uniform water. We have demonstrated an analytic formalism and procedure to determine a compensating material in the general case of multiple layers of arbitrary material. This work was supported by the US Army Medical Research and Materiel Command under Contract Agreement No. DAMD17-W81XWH-04-2-0022. Opinions, interpretations, conclusions and recommendations are those of the author and are not necessarily endorsed by the US Army.« less

Simulation of Mini-Magnetospheric Plasma Propulsion (M2P2) Interacting with an External Plasma Wind

NASA Technical Reports Server (NTRS)

Winglee, R. M.; Euripides, P.; Ziemba, T.; Slough, J.; Giersch, L.

2003-01-01

Substantial progress has been made over the last year in the development of the laboratory Mini-Magnetospheric Plasma Propulsion (M2P2) prototype. The laboratory testing has shown that that the plasma can be produced at high neutral gas efficiency, at high temperatures (a few tens of eV) with excellent confinement up to the point where chamber wall interactions dominate the physics. This paper investigates the performance of the prototype as it is opposed by an external plasma acting as a surrogate for the solar wind. The experiments were performed in 5ft diameter by 6ft long vacuum chamber at the University of Washington. The solar wind source comprised of a 33 kWe arc jet attached to a 200 kWe inductively generated plasma source. The dual plasma sources allow the interaction to be studied for different power levels, shot duration and production method. It is shown that plasma from the solar wind source (SWS) is able to penetrate the field of the M2P2 magnetic when no plasma is present. With operation of the M2P2 plasma source at only 1.5 kWe, the penetration of the SWS even at the highest power of operation at 200 kWe is stopped. This deflection is shown to be greatly enhanced over that produced by the magnet alone. In addition it is shown that with the presence of the SWS, M2P2 is able to produce enhanced magnetized plasma production out to at least 10 magnet radii where the field strength is only marginally greater than the terrestrial field. The results are consistent with the initial predictions that kWe M2P2 systems would be able to deflect several hundred kWe plasma winds to produce enhanced propulsion for a spacecraft.

Vehicle-Level Oxygen/Methane Propulsion System Hotfire Testing at Thermal Vacuum Conditions

NASA Technical Reports Server (NTRS)

Morehead, Robert L.; Melcher, J. C.; Atwell, Matthew J.; Hurlbert, Eric A.; Desai, Pooja; Werlink, Rudy

2017-01-01

A prototype integrated liquid oxygen/liquid methane propulsion system was hot-fire tested at a variety of simulated altitude and thermal conditions in the NASA Glenn Research Center Plum Brook Station In-Space Propulsion Thermal Vacuum Chamber (formerly B2). This test campaign served two purposes: 1) Characterize the performance of the Plum Brook facility in vacuum accumulator mode and 2) Collect the unique data set of an integrated LOX/Methane propulsion system operating in high altitude and thermal vacuum environments (a first). Data from this propulsion system prototype could inform the design of future spacecraft in-space propulsion systems, including landers. The test vehicle for this campaign was the Integrated Cryogenic Propulsion Test Article (ICPTA), which was constructed for this project using assets from the former Morpheus Project rebuilt and outfitted with additional new hardware. The ICPTA utilizes one 2,800 lbf main engine, two 28 lbf and two 7 lbf reaction control engines mounted in two pods, four 48-inch propellant tanks (two each for liquid oxygen and liquid methane), and a cold helium system for propellant tank pressurization. Several hundred sensors on the ICPTA and many more in the test cell collected data to characterize the operation of the vehicle and facility. Multiple notable experiments were performed during this test campaign, many for the first time, including pressure-fed cryogenic reaction control system characterization over a wide range of conditions, coil-on-plug ignition system demonstration at the vehicle level, integrated main engine/RCS operation, and a non-intrusive propellant mass gauging system. The test data includes water-hammer and thermal heat leak data critical to validating models for use in future vehicle design activities. This successful test campaign demonstrated the performance of the updated Plum Brook In-Space Propulsion thermal vacuum chamber and incrementally advanced the state of LOX/Methane propulsion technology through numerous system-level and subsystem experiments.

[Taylor and Hill, Incorporated's JSC Cryo Chamber A

NASA Technical Reports Server (NTRS)

Morales, Rito

2008-01-01

NASA commissioned construction of an environmental simulation test chamber which was completed in 1964 at Johnson Space Center (JSC) in Houston, Texas. The facility, Chamber A, was invaluable for testing spacecraft and satellites before deployment to space. By testing spacecraft in an environment similar to the one they would be functioning in, potential problems could be addressed before launch. A new addition to NASA's observatory inventory is called the James Webb Space Telescope (JWST), after a former Administrator of NASA. The new telescope will have 7 times the mirror area of the Hubble, with a target destination approximately one million miles from earth. Scheduled for launch in 2013, the JWST will allow scientists the ability to see, for the first time, the first galaxies that formed in the early Universe. Pre-launch testing of JWST must be performed in environments that approximate its final target space environment as closely as possible.

Engine combustion control via fuel reactivity stratification

DOEpatents

Reitz, Rolf Deneys; Hanson, Reed M.; Splitter, Derek A.; Kokjohn, Sage L.

2015-07-14

A compression ignition engine uses two or more fuel charges having two or more reactivities to control the timing and duration of combustion. In a preferred implementation, a lower-reactivity fuel charge is injected or otherwise introduced into the combustion chamber, preferably sufficiently early that it becomes at least substantially homogeneously dispersed within the chamber before a subsequent injection is made. One or more subsequent injections of higher-reactivity fuel charges are then made, and these preferably distribute the higher-reactivity matter within the lower-reactivity chamber space such that combustion begins in the higher-reactivity regions, and with the lower-reactivity regions following thereafter. By appropriately choosing the reactivities of the charges, their relative amounts, and their timing, combustion can be tailored to achieve optimal power output (and thus fuel efficiency), at controlled temperatures (and thus controlled NOx), and with controlled equivalence ratios (and thus controlled soot).

Engine combustion control via fuel reactivity stratification

DOEpatents

Reitz, Rolf Deneys; Hanson, Reed M.; Splitter, Derek A.; Kokjohn, Sage L.

2016-06-28

A compression ignition engine uses two or more fuel charges having two or more reactivities to control the timing and duration of combustion. In a preferred implementation, a lower-reactivity fuel charge is injected or otherwise introduced into the combustion chamber, preferably sufficiently early that it becomes at least substantially homogeneously dispersed within the chamber before a subsequent injection is made. One or more subsequent injections of higher-reactivity fuel charges are then made, and these preferably distribute the higher-reactivity matter within the lower-reactivity chamber space such that combustion begins in the higher-reactivity regions, and with the lower-reactivity regions following thereafter. By appropriately choosing the reactivities of the charges, their relative amounts, and their timing, combustion can be tailored to achieve optimal power output (and thus fuel efficiency), at controlled temperatures (and thus controlled NOx), and with controlled equivalence ratios (and thus controlled soot).

Engine combustion control via fuel reactivity stratification

DOEpatents

Reitz, Rolf Deneys; Hanson, Reed M; Splitter, Derek A; Kokjohn, Sage L

2013-12-31

A compression ignition engine uses two or more fuel charges having two or more reactivities to control the timing and duration of combustion. In a preferred implementation, a lower-reactivity fuel charge is injected or otherwise introduced into the combustion chamber, preferably sufficiently early that it becomes at least substantially homogeneously dispersed within the chamber before a subsequent injection is made. One or more subsequent injections of higher-reactivity fuel charges are then made, and these preferably distribute the higher-reactivity matter within the lower-reactivity chamber space such that combustion begins in the higher-reactivity regions, and with the lower-reactivity regions following thereafter. By appropriately choose the reactivities of the charges, their relative amounts, and their timing, combustion can be tailored to achieve optimal power output (and thus fuel efficiency), at controlled temperatures (and thus controlled NOx), and with controlled equivalence ratios (and thus controlled soot).

Late glaucoma after interstitial keratitis.

PubMed

Grant, W M

1975-01-01

In a systematic study of 45 patients who had syphilitic interstitial keratitis early in life and, many years later, were discovered to have glaucoma, there was evidence of two different but equally common mechanisms. In one group of patients, a deep-chamber type of glaucoma was superimposed on old inflammatory changes, was characteristically refractory to medical treatment, but did well with filtering surgery. The other group of patients had reversible angle-closure glaucoma associated with anatomically small anterior segments, and typically responded well to iridectomy. The late, refractory, deep-chamber type of glaucoma may involve endothelialization and formation of glass membrane in the angle, as seen in one excised eye. Occurrence of the shallow-chamber, reversible angle-closure type of glaucoma after interstitial keratitis may be coincidental, since no other evidence supports the idea that small anterior segments might be particularly prevalent among patients who have had congenital syphilis or interstitial keratitis.

Decomposition of blackberry and broomsedge bluestem as influenced by ozone

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kim, J.S.; Chappelka, A.H.; Miller-Goodman, M.S.

Many researchers have reported on individual plant responses to O{sub 3}, but few have investigated the effects of this pollutant on ecosystem function. This investigation examined the influence of O{sub 3} on short-term (Phase 1) litter decomposition of blackberry (Rubus cuneifolus Pursh.) and broomsedge bluestem (Andropogon virginicus L.), two plant species native to early successional forest communities in the southern US. Mixed blackberry/broomsedge litter (1:1) collected from plants exposed to different levels of O{sub 3} for one growing season was placed in open-top chambers and exposed to different O{sub 3} levels of treatments for 24 weeks. Litter also was incubatedmore » in microcosms in the laboratory t 25 or 30 C to determine the effects of climate change on O{sub 3}-treated litter. Initial C and N concentrations of the collected foliage did not differ significantly among treatments for either species. Blackberry litter had approximately twice as much N as broomsedge, and when collected from 2X O{sub 3} chambers, had significantly greater permanganate lignin than the other treatments. Initial permanganate lignin concentration of blackberry, over all O{sub 3} treatments, correlated significantly with remaining mass of the litter mixture after 24 wk exposure. Litter decomposed more slowly in the 2X chambers than in the other treatment chambers, regardless of litter source. Elevated O{sub 3}-exposed litter (2X) decomposed the slowest regardless of treatment applied. There were significant temperature and time effects observed with litter decomposition: litter incubated at 30 C decomposed faster than at 25 C. The data suggest O{sub 3} may influence substrate quality and microbial activity, thus reducing the rate of litter decomposition in early successional forest communities.« less

Modification of Experimental Protocols for a Space Shuttle Flight and Applications for the Analysis of Cytoskeletal Structures During Fertilization, Cell Division , and Development in Sea Urchin Embryos

NASA Technical Reports Server (NTRS)

Chakrabarti, Amitabha; Stoecker, Andrew; Schatten, Heide

1995-01-01

To explore the role of microgravity on cytoskeletal organization and skeletal calcium deposition during fertilization, cell division, and early development, the sea urchin was chosen as a model developmental system. Methods were developed to employ light, immunofluorescence, and electron microscopy on cultures being prepared for flight on the Space Shuttle. For analysis of microfilaments, microtubules, centrosomes, and calcium-requiring events, our standard laboratory protocols had to be modified substantially for experimentation on the Space Shuttle. All manipulations were carried out in a closed culture chamber containing 35 ml artificial sea water as a culture fluid. Unfertilized eggs stored for 24 hours in these chambers were fertilized with sperm diluted in sea water and fixed with concentrated fixatives for final fixation in formaldehyde, taxol, EGTA, and MgCl2(exp -6)H2O for 1 cell to 16 cell stages to preserve cytoskeletal structures for simultaneous analysis with light, immunofluorescence, and electron microscopy, and 1.5 percent glutaraldehyde and 0.4 percent formaldehyde for blastula and plueus stages. The fixed samples wre maintained in chambers without degradation for up to two weeks after which the specimens were processed and analyzed with routine methods. Since complex manipulations are not possible in the closed chambers, the fertilization coat was removed from fixation using 0.5 percent freshly prepared sodium thioglycolate solution at pH 10.0 which provided reliable immunofluorescence staining for microtubules. Sperm/egg fusion, mitosis, cytokinesis, and calcium deposition during spicule formatin in early embryogenesis were found to be without artificial alterations when compared to cells fixed fresh and processed with conventional methods.

Ancient DNA analysis might suggest external origin of individuals from chamber graves placed in medieval cemetery in Pień, Central Poland.

PubMed

Płoszaj, Tomasz; Jędrychowska-Dańska, Krystyna; Zamerska, Alicja; Drozd-Lipińska, Alicja; Poliński, Dariusz; Janowski, Andrzej; Witas, Henryk

2017-12-01

The participation of immigrants during early days in Poland of Piast's dynasty is a debated issue among archaeologists and anthropologists alike. Such hypotheses were formulated on the basis of, amongst others, the discovery of early medieval chamber graves characterized by construction features typical of the Scandinavian culture area. Archaeological and anthropological studies to date have not provided an unequivocal answer as to whether the individuals interred in those graves were autochthons who adopted a different burial rite, or perhaps immigrants from foreign lands. To characterize the gene pool of this population we analyzed the C/T allele of the nuclear gene LCT-13910 as well as fragments of the mitochondrial genome from individuals buried in very richly furnished chamber graves at the medieval cemetery in Pień. The obtained results for the nuclear allele and mtDNA do not corroborate the Scandinavian origin of the analyzed population. Moreover, we did not find haplogroup I, which is the one typical of populations that historically inhabited the north of Europe; and the frequency of the LCT-13910 T allele was similar to that of past and present Polish populations. On the other hand, we identified the atypical haplogroup C5c1, which suggests Asian origin of the studied individuals and confirms our previous reports concerning ancient human migrations from Asia to the territory of present-day Poland. While our findings do not conclusively disprove a Scandinavian lineage of the studied population, they certainly shed some new light on the origin of the individuals buried in chamber graves, which may be very different from the one initially proposed by archaeologists.

Analysis of the kinestatic charge detection system as a high detective quantum efficiency electronic portal imaging device.

PubMed

Samant, Sanjiv S; Gopal, Arun

2006-09-01

Megavoltage x-ray imaging suffers from reduced image quality due to low differential x-ray attenuation and large Compton scatter compared with kilovoltage imaging. Notwithstanding this, electronic portal imaging devices (EPIDs) are now widely used in portal verification in radiotherapy as they offer significant advantages over film, including immediate digital imaging and superior contrast range. However video-camera-based EPIDs (VEPIDs) are limited by problems of low light collection efficiency and significant light scatter, leading to reduced contrast and spatial resolution. Indirect and direct detection-based flat-panel EPIDs have been developed to overcome these limitations. While flat-panel image quality has been reported to exceed that achieved with portal film, these systems have detective quantum efficiency (DQE) limited by the thin detection medium and are sensitive to radiation damage to peripheral read-out electronics. An alternative technology for high-quality portal imaging is presented here: kinesatic charge detection (KCD). The KCD is a scanning tri-electrode ion-chamber containing high-pressure noble gas (xenon at 100 atm) used in conjunction with a strip-collimated photon beam. The chamber is scanned across the patient, and an external electric field is used to regulate the cation drift velocity. By matching the scanning velocity with that of the cation (i.e., ion) drift velocity, the cations remain static in the object frame of reference, allowing temporal integration of the signal. The KCD offers several advantages as a portal imaging system. It has a thick detector geometry with an active detection depth of 6.1 cm, compared to the sub-millimeter thickness of the phosphor layer in conventional phosphor screens, leading to an order of magnitude advantage in quantum efficiency (>0.3). The unique principle of and the use of the scanning strip-collimated x-ray beam provide further integration of charges in time, reduced scatter, and a significantly reduced imaging dose, enhancing the imaging signal-to-noise ratio (SNR) and leading to high DQE. While thick detectors usually suffer from reduced spatial resolution, the KCD provides good spatial resolution due to high gas pressure that limits the spread of scattered electrons, and a strip-collimated beam that significantly reduces the inclusion of scatter in the imaging signal. A 10 cm wide small-field-of-view (SFOV) prototype of the KCD is presented with a complete analysis of its imaging performance. Measurements of modulation transfer function (MTF), noise power spectrum (NPS), and DQE were in good agreement with Monte Carlo simulations. Imaging signal loss from recombination within the KCD chamber was measured at different gas pressures, ion drift velocities, and strip-collimation widths. Image quality for the prototype KCD was also observed with anthropomorphic phantom imaging in comparison with various commercial and research portal imaging systems, including VEPID, flat-panel imager, and conventional and high contrast film systems. KCD-based imaging provided very good contrast and good spatial resolution at very low imaging dose (0.1 cGy per image). For the prototype KCD, measurements yielded DQE(0)=0.19 and DQE(1 cy/mm)=0.004.

Albemarle County roads, 1725-1816.

DOT National Transportation Integrated Search

1981-01-01

This publication is the result of an effort to write a history of the early road system of Albemarle County which could be used as a prototype for similar histories of other areas. This has involved research in such primary sources as court records, ...

SU-E-T-259: Development of a Primary Standard for LDR Brachytherapy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shen, H; McEwen, M

Purpose: The National Research Council initiated a program in 2012 to develop a primary standard to calibrate I-125 and Pd-103 sources used for LDR brachytherapy and disseminate this through calibration services to Canadian users. This will simplify procedures as Canadian cancer centres currently have to ship instruments to the US. Methods: The standard is based on a commercial version of the wide-angle free air chamber (WAFAC) pioneered by NIST. Significant enhancements were implemented to improve signal-to-noise and measurement reproducibility and eliminate electric field effects. Validation of this ionization chamber was then carried out in a low-energy X -ray beam (∼more » 31 keV) where the dose rate had been previously established using the existing NRC primary standard free-air chamber. As a final component of this initial testing, measurements were made with a set of I-125 seeds (with air kerma strength traceable to NIST). Results: Excellent agreement of the two NRC free-air chambers was obtained within the combined standard uncertainty of 0.5 %. However, it was found that the WAFAC response is very sensitive to the beam geometry (distance from the source, diameter of the beam-defining aperture, etc) and Monte Carlo calculations, carried out to evaluate these geometry corrections, have confirmed the experimental results. The results for the seed measurements indicated a precision of better than 1 % is achievable for a reasonable acquisition time and the air kerma strength agreed with the manufacturer (NIST-traceable) value within 2 %. Conclusion: The prototype primary standard for LDR brachytherapy has met accuracy target of 3 % for the determination of air kerma strength. Work is ongoing to refine operation of the device and develop the calibration protocol for clinical users, with an anticipated launch of a calibration service in late 2015.« less

Association between left atrial phasic conduit function and early atrial fibrillation recurrence in patients undergoing electrical cardioversion.

PubMed

Degiovanni, Anna; Boggio, Enrico; Prenna, Eleonora; Sartori, Chiara; De Vecchi, Federica; Marino, Paolo N

2018-04-01

Diastolic dysfunction promotes atrial fibrillation (AF) inducing left atrial (LA) remodeling, with chamber dilation and fibrosis. Predominance of LA phasic conduit (LAC) function should reflect not only chamber alterations but also underlying left ventricular (LV) filling impairment. Thus, LAC was tested as possible predictor of early AF relapse after electrical cardioversion (EC). 96 consecutive patients, who underwent EC for persistent non-valvular AF, were prospectively enrolled. Immediately after successful EC (3 h ± 15 min), an echocardiographic apical four-chamber view was acquired with transmitral velocities, annular tissue Doppler and simultaneous LV and LA three-dimensional full-volume datasets. Then, from LA-LV volumetric curves we computed LAC as: [(LV maximum - LV minimum) - (LA maximum - LA minimum) volume], expressed as % LV stroke volume. LA pump, immediately post-EC, was assumed and verified as being negligible. Sinus rhythm persistence at 1 month was checked with ECG-Holter monitoring. At 1 month 62 patients were in sinus rhythm and 34 in AF. AF patients presented pre-EC higher E/é values (p = 0.012), no major LA volume differences (p = NS), but a stiffer LV cavity (p = 0.012) for a comparable LV capacitance (p = 0.461). Conduit contributed more (p < 0.001) to LV stroke volume in AF subpopulation. Multiple regression revealed LAC as the most significant AF predictor (p = 0.013), even after correction for biometric characteristics and pharmacotherapy (p = 0.008). Our data suggest that LAC larger contribution to LV filling soon after EC reflects LA-LV stiffening, which skews atrioventricular interaction leading to AF perpetuation and makes conduit dominance a powerful predictor of early AF recurrence.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Togno, M., E-mail: michele.togno@iba-group.com; Department of Radiation Oncology, Technische Universität München, Klinikum rechts der Isar, Munich 81675; IBA Dosimetry GmbH, Schwarzenbruck 90592

Purpose: To characterize a new air vented ionization chamber technology, suitable to build detector arrays with small pixel pitch and independence of sensitivity on dose per pulse. Methods: The prototype under test is a linear array of air vented ionization chambers, consisting of 80 pixels with 3.5 mm pixel pitch distance and a sensitive volume of about 4 mm{sup 3}. The detector has been characterized with {sup 60}Co radiation and MV x rays from different linear accelerators (with flattened and unflattened beam qualities). Sensitivity dependence on dose per pulse has been evaluated under MV x rays by changing both themore » source to detector distance and the beam quality. Bias voltage has been varied in order to evaluate the charge collection efficiency in the most critical conditions. Relative dose profiles have been measured for both flattened and unflattened distributions with different field sizes. The reference detectors were a commercial array of ionization chambers and an amorphous silicon flat panel in direct conversion configuration. Profiles of dose distribution have been measured also with intensity modulated radiation therapy (IMRT), stereotactic radiosurgery (SRS), and volumetric modulated arc therapy (VMAT) patient plans. Comparison has been done with a commercial diode array and with Gafchromic EBT3 films. Results: Repeatability and stability under continuous gamma irradiation are within 0.3%, in spite of low active volume and sensitivity (∼200 pC/Gy). Deviation from linearity is in the range [0.3%, −0.9%] for a dose of at least 20 cGy, while a worsening of linearity is observed below 10 cGy. Charge collection efficiency with 2.67 mGy/pulse is higher than 99%, leading to a ±0.9% sensitivity change in the range 0.09–2.67 mGy/pulse (covering all flattened and unflattened beam qualities). Tissue to phantom ratios show an agreement within 0.6% with the reference detector up to 34 cm depth. For field sizes in the range 2 × 2 to 15 × 15 cm{sup 2}, the output factors are in agreement with a thimble chamber within 2%, while with 25 × 25 cm{sup 2} field size, an underestimation of 4.0% was found. Agreement of field and penumbra width measurements with the flat panel is of the order of 1 mm down to 1 × 1 cm{sup 2} field size. Flatness and symmetry values measured with the 1D array and the reference detectors are comparable, and differences are always smaller than 1%. Angular dependence of the detector, when compared to measurements taken with a cylindrical chamber in the same phantom, is as large as 16%. This includes inhomogeneity and asymmetry of the design, which during plan verification are accounted for by the treatment planning system (TPS). The detector is capable to reproduce the dose distributions of IMRT and VMAT plans with a maximum deviation from TPS of 3.0% in the target region. In the case of VMAT and SRS plans, an average (maximum) deviation of the order of 1% (4%) from films has been measured. Conclusions: The investigated technology appears to be useful both for Linac QA and patient plan verification, especially in treatments with steep dose gradients and nonuniform dose rates such as VMAT and SRS. Major limitations of the present prototype are the linearity at low dose, which can be solved by optimizing the readout electronics, and the underestimation of output factors with large field sizes. The latter problem is presently not completely understood and will require further investigations.« less

Compression under a mechanical counter pressure space suit glove

NASA Technical Reports Server (NTRS)

Waldie, James M A.; Tanaka, Kunihiko; Tourbier, Dietmar; Webb, Paul; Jarvis, Christine W.; Hargens, Alan R.

2002-01-01

Background: Current gas-pressurized space suits are bulky stiff shells severely limiting astronaut function and capability. A mechanical counter pressure (MCP) space suit in the form of a tight elastic garment could dramatically improve extravehicular activity (EVA) dexterity, but also be advantageous in safety, cost, mass and volume. The purpose of this study was to verify that a prototype MCP glove exerts the design compression of 200 mmHg, a pressure similar to the current NASA EVA suit. Methods: Seven male subjects donned a pressure measurement array and MCP glove on the right hand, which was placed into a partial vacuum chamber. Average compression was recorded on the palm, the bottom of the middle finger, the top of the middle finger and the dorsum of the hand at pressures of 760 (ambient), 660 and 580 mmHg. The vacuum chamber was used to simulate the pressure difference between the low breathing pressure of the current NASA space suits (approximately 200 mmHg) and an unprotected hand in space. Results: At ambient conditions, the MCP glove compressed the dorsum of the hand at 203.5 +/- 22.7 mmHg, the bottom of the middle finger at 179.4 +/- 16.0 mmHg, and the top of the middle finger at 183.8 +/- 22.6 mmHg. The palm compression was significantly lower (59.6 +/- 18.8 mmHg, p<0.001). There was no significant change in glove compression with the chamber pressure reductions. Conclusions: The MCP glove compressed the dorsum of the hand and middle finger at the design pressure.

Compression under a mechanical counter pressure space suit glove.

PubMed

Waldie, James M A; Tanaka, Kunihiko; Tourbier, Dietmar; Webb, Paul; Jarvis, Christine W; Hargens, Alan R

2002-12-01

Current gas-pressurized space suits are bulky stiff shells severely limiting astronaut function and capability. A mechanical counter pressure (MCP) space suit in the form of a tight elastic garment could dramatically improve extravehicular activity (EVA) dexterity, but also be advantageous in safety, cost, mass and volume. The purpose of this study was to verify that a prototype MCP glove exerts the design compression of 200 mmHg, a pressure similar to the current NASA EVA suit. Seven male subjects donned a pressure measurement array and MCP glove on the right hand, which was placed into a partial vacuum chamber. Average compression was recorded on the palm, the bottom of the middle finger, the top of the middle finger and the dorsum of the hand at pressures of 760 (ambient), 660 and 580 mmHg. The vacuum chamber was used to simulate the pressure difference between the low breathing pressure of the current NASA space suits (approximately 200 mmHg) and an unprotected hand in space. At ambient conditions, the MCP glove compressed the dorsum of the hand at 203.5 +/- 22.7 mmHg, the bottom of the middle finger at 179.4 +/- 16.0 mmHg, and the top of the middle finger at 183.8 +/- 22.6 mmHg. The palm compression was significantly lower (59.6 +/- 18.8 mmHg, p<0.001). There was no significant change in glove compression with the chamber pressure reductions. The MCP glove compressed the dorsum of the hand and middle finger at the design pressure.

Development of a GNSS-Enhanced Tsunami Early Warning System

NASA Astrophysics Data System (ADS)

Bawden, G. W.; Melbourne, T. I.; Bock, Y.; Song, Y. T.; Komjathy, A.

2015-12-01

The past decade has witnessed a terrible loss of life and economic disruption caused by large earthquakes and resultant tsunamis impacting coastal communities and infrastructure across the Indo-Pacific region. NASA has funded the early development of a prototype real-time Global Navigation Satellite System (RT-GNSS) based rapid earthquake and tsunami early warning (GNSS-TEW) system that may be used to enhance seismic tsunami early warning systems for large earthquakes. This prototype GNSS-TEW system geodetically estimates fault parameters (earthquake magnitude, location, strike, dip, and slip magnitude/direction on a gridded fault plane both along strike and at depth) and tsunami source parameters (seafloor displacement, tsunami energy scale, and 3D tsunami initials) within minutes after the mainshock based on dynamic numerical inversions/regressions of the real-time measured displacements within a spatially distributed real-time GNSS network(s) spanning the epicentral region. It is also possible to measure fluctuations in the ionosphere's total electron content (TEC) in the RT-GNSS data caused by the pressure wave from the tsunami. This TEC approach can detect if a tsunami has been triggered by an earthquake, track its waves as they propagate through the oceanic basins, and provide upwards of 45 minutes early warning. These combined real-time geodetic approaches will very quickly address a number of important questions in the immediate minutes following a major earthquake: How big was the earthquake and what are its fault parameters? Could the earthquake have produced a tsunami and was a tsunami generated?

Biomechanics of Early Cardiac Development

PubMed Central

Goenezen, Sevan; Rennie, Monique Y.

2012-01-01

Biomechanics affect early cardiac development, from looping to the development of chambers and valves. Hemodynamic forces are essential for proper cardiac development, and their disruption leads to congenital heart defects. A wealth of information already exists on early cardiac adaptations to hemodynamic loading, and new technologies, including high resolution imaging modalities and computational modeling, are enabling a more thorough understanding of relationships between hemodynamics and cardiac development. Imaging and modeling approaches, used in combination with biological data on cell behavior and adaptation, are paving the road for new discoveries on links between biomechanics and biology and their effect on cardiac development and fetal programming. PMID:22760547

Estimating millet production for famine early warning: An application of crop simulation modelling using satellite and ground-based data in Burkina Faso

USGS Publications Warehouse

Thornton, P. K.; Bowen, W. T.; Ravelo, A.C.; Wilkens, P. W.; Farmer, G.; Brock, J.; Brink, J. E.

1997-01-01

Early warning of impending poor crop harvests in highly variable environments can allow policy makers the time they need to take appropriate action to ameliorate the effects of regional food shortages on vulnerable rural and urban populations. Crop production estimates for the current season can be obtained using crop simulation models and remotely sensed estimates of rainfall in real time, embedded in a geographic information system that allows simple analysis of simulation results. A prototype yield estimation system was developed for the thirty provinces of Burkina Faso. It is based on CERES-Millet, a crop simulation model of the growth and development of millet (Pennisetum spp.). The prototype was used to estimate millet production in contrasting seasons and to derive production anomaly estimates for the 1986 season. Provincial yields simulated halfway through the growing season were generally within 15% of their final (end-of-season) values. Although more work is required to produce an operational early warning system of reasonable credibility, the methodology has considerable potential for providing timely estimates of regional production of the major food crops in countries of sub-Saharan Africa.

Prototype early warning system for heart disease detection using Android Application.

PubMed

Zennifa, Fadilla; Fitrilina; Kamil, Husnil; Iramina, Keiji

2014-01-01

Heart Disease affects approximately 70 million people worldwide where most people do not even know the symptoms. This research examines the prototype of early warning system for heart disease by android application. It aims to facilitate users to early detect heart disease which can be used independently. To build the application in android phone, variable centered intelligence rule system (VCIRS) as decision makers and pulse sensor - Arduino as heart rate detector were applied in this study. Moreover, in Arduino, the heart rate will become an input for symptoms in Android Application. The output of this system is the conclusion statement of users diagnosed with either coronary heart disease, hypertension heart disease, rheumatic heart disease or do not get any kind of heart disease. The result of diagnosis followed by analysis of the value of usage variable rate (VUR) rule usage rate (RUR) and node usage rate (NUR) that shows the value of the rule that will increase when the symptoms frequently appear. This application was compared with the medical analysis from 35 cases of heart disease and it showed concordance between diagnosis from android application and expert diagnosis of the doctors.

PET with the HIDAC camera?

NASA Astrophysics Data System (ADS)

Townsend, D. W.

1988-06-01

In 1982 the first prototype high density avalanche chamber (HIDAC) positron camera became operational in the Division of Nuclear Medicine of Geneva University Hospital. The camera consisted of dual 20 cm × 20 cm HIDAC detectors mounted on a rotating gantry. In 1984, these detectors were replaced by 30 cm × 30 cm detectors with improved performance and reliability. Since then, the larger detectors have undergone clinical evaluation. This article discusses certain aspects of the evaluation program and the conclusions that can be drawn from the results. The potential of the HIDAC camera for quantitative positron emission tomography (PET) is critically examined, and its performance compared with a state-of-the-art, commercial ring camera. Guidelines for the design of a future HIDAC camera are suggested.

Production and characterization of large-area sputtered selective solar absorber coatings

NASA Astrophysics Data System (ADS)

Graf, Wolfgang; Koehl, Michael; Wittwer, Volker

1992-11-01

Most of the commercially available selective solar absorber coatings are produced by electroplating. Often the reproducibility or the durability of their optical properties is not very satisfying. Good reproducibility can be achieved by sputtering, the technique for the production of low-(epsilon) coatings for windows. The suitability of this kind of deposition technique for flat-plate solar absorber coatings based on the principle of ceramic/metal composites was investigated for different material combinations, and prototype collectors were manufactured. The optical characterization of the coatings is based on spectral measurements of the near-normal/hemispherical and the angle-dependent reflectance in the wavelength-range 0.38 micrometers - 17 micrometers . The durability assessment was carried out by temperature tests in ovens and climatic chambers.

Dynamic cell culture system: a new cell cultivation instrument for biological experiments in space

NASA Technical Reports Server (NTRS)

Gmunder, F. K.; Nordau, C. G.; Tschopp, A.; Huber, B.; Cogoli, A.

1988-01-01

The prototype of a miniaturized cell cultivation instrument for animal cell culture experiments aboard Spacelab is presented (Dynamic cell culture system: DCCS). The cell chamber is completely filled and has a working volume of 200 microliters. Medium exchange is achieved with a self-powered osmotic pump (flowrate 1 microliter h-1). The reservoir volume of culture medium is 230 microliters. The system is neither mechanically stirred nor equipped with sensors. Hamster kidney (Hak) cells growing on Cytodex 3 microcarriers were used to test the biological performance of the DCCS. Growth characteristics in the DCCS, as judged by maximal cell density, glucose consumption, lactic acid secretion and pH, were similar to those in cell culture tubes.

The Role of Habitability Studies in Space Facility and Vehicle Design

NASA Technical Reports Server (NTRS)

Adams, Constance M.

1999-01-01

This document is a viewgraph presentation which reviews the role of the space architect in designing a space vehicle with habitability as a chief concern. Habitability is composed of the qualities of the environment or system which support the crew in working and living. All the impacts from habitability are interdependent; i.e., impacts to well-being can impact performance, safety or efficiency. After reviewing the issues relating to habitability the presentation discusses the application of these issues in two case studies. The first studies the Bio-Plex Hab chamber which includes designs of the living and working areas. The second case study is the ISS-TransHab which is being studied as a prototype for Mars transit.

A fluid model simulation of a simplified plasma limiter based on spectral-element time-domain method

DOE Office of Scientific and Technical Information (OSTI.GOV)

Qian, Cheng; Ding, Dazhi, E-mail: dzding@njust.edu.cn; Fan, Zhenhong

2015-03-15

A simplified plasma limiter prototype is proposed and the fluid model coupled with Maxwell's equations is established to describe the operating mechanism of plasma limiter. A three-dimensional (3-D) simplified sandwich structure plasma limiter model is analyzed with the spectral-element time-domain (SETD) method. The field breakdown threshold of air and argon at different frequency is predicted and compared with the experimental data and there is a good agreement between them for gas microwave breakdown discharge problems. Numerical results demonstrate that the two-layer plasma limiter (plasma-slab-plasma) has better protective characteristics than a one-layer plasma limiter (slab-plasma-slab) with the same length of gasmore » chamber.« less

Icebreaker-3 Drill Integration and Testing at Two Mars-Analog Sites

NASA Technical Reports Server (NTRS)

Glass, B.; Bergman, D.; Yaggi, B.; Dave, A.; Zacny, K.

2016-01-01

A decade of evolutionary development of integrated automated drilling and sample handling at analog sites and in test chambers has made it possible to go 1 meter through hard rocks and ice layers on Mars. The latest Icebreaker-3 drill has been field tested in 2014 at the Haughton Crater Marsanalog site in the Arctic and in 2015 with a Mars lander mockup in Rio Tinto, Spain, (with sample transfer arm and with a prototype life-detection instrument). Tests in Rio Tinto in 2015 successfully demonstrated that the drill sample (cuttings) was handed-off from the drill to the sample transfer arm and thence to the on-deck instrument inlet where it was taken in and analyzed ("dirt-to-data").

J-PET: A New Technology for the Whole-body PET Imaging

NASA Astrophysics Data System (ADS)

Niedźwiecki, S.; Białas, P.; Curceanu, C.; Czerwiński, E.; Dulski, K.; Gajos, A.; Głowacz, B.; Gorgol, M.; Hiesmayr, B. C.; Jasińska, B.; Kapłon, Ł.; Kisielewska-Kamińska, D.; Korcyl, G.; Kowalski, P.; Kozik, T.; Krawczyk, N.; Krzemień, W.; Kubicz, E.; Mohammed, M.; Pawlik-Niedźwiecka, M.; Pałka, M.; Raczyński, L.; Rudy, Z.; Sharma, N. G.; Sharma, S.; Shopa, R. Y.; Silarski, M.; Skurzok, M.; Wieczorek, A.; Wiślicki, W.; Zgardzińska, B.; Zieliński, M.; Moskal, P.

The Jagiellonian Positron Emission Tomograph (J-PET) is the first PET built from plastic scintillators. J-PET prototype consists of 192 detection modules arranged axially in three layers forming a cylindrical diagnostic chamber with the inner diameter of 85 cm and the axial field-of-view of 50 cm. An axial arrangement of long strips of plastic scintillators, their small light attenuation, superior timing properties, and relative ease of the increase of the axial field-of-view opens promising perspectives for the cost effective construction of the whole-body PET scanner, as well as construction of MR and CT compatible PET inserts. Present status of the development of the J-PET tomograph will be presented and discussed.

KSC-2012-4238

NASA Image and Video Library

2012-08-03

CAPE CANAVERAL, Fla. – Inside the Space Life Sciences Laboratory, or SLSL, at NASA’s Kennedy Space Center in Florida, radish plants are being harvested in a plant growth chamber. The plants were grown under red and blue LED lights. The plant experiment at Kennedy is part of the Advanced Exploration Systems, or AES, program in NASA’s Human Exploration and Operations Mission Directorate. This plant experiment studies the effects of different types of lighting on plants such as radishes and leaf lettuce. Results of these studies will help provide information on how to grow food sources for deep space exploration missions. AES projects pioneer new approaches for rapidly developing prototype systems, demonstrating key capabilities and validating operational concepts for future human missions beyond Earth orbit. Photo credit: NASA/Frank Ochoa-Gonzales

KSC-2012-4241

NASA Image and Video Library

2012-08-03

CAPE CANAVERAL, Fla. – Inside the Space Life Sciences Laboratory, or SLSL, at NASA’s Kennedy Space Center in Florida, radish plants were harvested from a plant growth chamber. The plants were grown under red and blue LED lights. The plant experiment at Kennedy is part of the Advanced Exploration Systems, or AES, program in NASA’s Human Exploration and Operations Mission Directorate. This plant experiment studies the effects of different types of lighting on plants such as radishes and leaf lettuce. Results of these studies will help provide information on how to grow food sources for deep space exploration missions. AES projects pioneer new approaches for rapidly developing prototype systems, demonstrating key capabilities and validating operational concepts for future human missions beyond Earth orbit. Photo credit: NASA/Frank Ochoa-Gonzales

Hickam Air Force Base Fuel Cell Vehicles : Early Implementation Experience

DOT National Transportation Integrated Search

2008-07-01

This report describes operations at Alameda-Contra Costa Transit District (AC Transit) for three prototype fuel cell buses and six diesel buses operating from the same location. This is the third evaluation report for this site, and it describes new ...

Assessment of a drowsy driver warning system for heavy-vehicle drivers : final report

DOT National Transportation Integrated Search

2009-04-01

Drowsiness has a globally negative impact on performance, slowing reaction time, decreasing situational awareness, and impairing judgment. A field operational test of an early prototype Drowsy Driver Warning System was conducted as a result of 12 yea...

Feasibility of an orbital simulator of stratospheric photochemistry

NASA Technical Reports Server (NTRS)

Matloff, G. L.; Hoffert, M. I.

1978-01-01

It is proposed that a stratospheric photochemistry simulator could be created in sun-synchronous orbit, so that diffusion and photochemistry could be decoupled and uncertainties in photochemical reaction rates could be substantially reduced. The proposed test chamber is described, and it is suggested that the technology of superpressure balloons seems to be the best short-term solution to the construction of the proposed facility. Both unreinforced polyester films and gelatin films are considered as candidate chamber coatings. It is noted that the experiments can be performed early in the space-manufacturing era and that at least three dedicated Shuttle launches will be required to establish the proposed facility.

Daniel Chambers Macreight FRCP, FLS (1799-1856), a little-known, innovative Irish botanist.

PubMed

Nelson, E Charles

2009-01-01

Biographical information is provided for Daniel Chambers Macreight. He worked in Augustin-Pyramus de Candolle's herbarium at Geneva during the early 1830s, and later in the decade was prominent in medico-botanical circles in London. Macreight retired in 1840, due to ill-health, and moved to Jersey in the Channel Islands where he died. In 1837, he published an innovative "Manual of the British flora" which covered both native and cultivated plants. This flora contained two novel features: dichotomous keys were provided to assist students to identify plants, and the category subspecies was employed for taxa within the genera "Rosa," "Rubus" and "Salix."

The Effect of Jetting Parameters on the Performance of Droplet Formation for Ink-Jet Rapid Prototyping

NASA Technical Reports Server (NTRS)

Helmer, Wayne

1998-01-01

Heinzl et al. (1985) reports that experiments in ink-jets to produce drawings or signals occurred as early as 1930. Various companies such as IBM and Pitney-Bowes have conducted extensive studies on these devices for many years. Many such reports are available in such journals as the IBM Journal of Research and Development. While numerous articles have been published on the jetting characteristics of ink and water, the literature is rather limited on fluids such as waxes (Gao & Sonin 1994) or non-water based fluids (Passow, et al. 1993). This present study extends the knowledge base to determine the performance of molten waxes in "ink-jet" type printers for rapid prototyping. The purpose of this research was to qualitatively and quantitatively study the droplet formation of a drop-on-demand ink-jet type nozzle system for rapid prototyping.

Mechanisms of Family Impact on African American Adolescents’ HIV-Related Behavior

PubMed Central

Kogan, Steven M.; Brody, Gene H.; Gibbons, Frederick X.; Chen, Yi-fu; Grange, Christina M.; Simons, Ronald L.; Gerrard, Meg; Cutrona, Carolyn E.

2010-01-01

A longitudinal model that tested mediating pathways between protective family processes and HIV-related behavior was evaluated with 195 African American youth. Three waves of data were collected when the youth were 13, 15, and 19 years old. Evidence of mediation and temporal priority were assessed for three constructs: academic engagement, evaluations of prototypical risk-taking peers, and affiliations with risk-promoting peers. Structural equation modeling indicated that protective family processes assessed during early adolescence were associated with HIV-related behavior during emerging adulthood and that academic engagement, evaluations of prototypical risk-taking peers, and affiliations with risk-promoting peers accounted for this association. Evidence of a specific pathway emerged: protective family processes → academic engagement negative → evaluations of prototypical risk-taking peers→ affiliations with risk-promoting peers→ HIV-related behavior. Academic engagement also was a direct predictor of HIV-related risk behavior. PMID:21643492

SU-F-T-256: 4D IMRT Planning Using An Early Prototype GPU-Enabled Eclipse Workstation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hagan, A; Modiri, A; Sawant, A

Purpose: True 4D IMRT planning, based on simultaneous spatiotemporal optimization has been shown to significantly improve plan quality in lung radiotherapy. However, the high computational complexity associated with such planning represents a significant barrier to widespread clinical deployment. We introduce an early prototype GPU-enabled Eclipse workstation for inverse planning. To our knowledge, this is the first GPUintegrated Eclipse system demonstrating the potential for clinical translation of GPU computing on a major commercially-available TPS. Methods: The prototype system comprised of four NVIDIA Tesla K80 GPUs, with a maximum processing capability of 8.5 Tflops per K80 card. The system architecture consisted ofmore » three key modules: (i) a GPU-based inverse planning module using a highly-parallelizable, swarm intelligence-based global optimization algorithm, (ii) a GPU-based open-source b-spline deformable image registration module, Elastix, and (iii) a CUDA-based data management module. For evaluation, aperture fluence weights in an IMRT plan were optimized over 9 beams,166 apertures and 10 respiratory phases (14940 variables) for a lung cancer case (GTV = 95 cc, right lower lobe, 15 mm cranio-caudal motion). Sensitivity of the planning time and memory expense to parameter variations was quantified. Results: GPU-based inverse planning was significantly accelerated compared to its CPU counterpart (36 vs 488 min, for 10 phases, 10 search agents and 10 iterations). The optimized IMRT plan significantly improved OAR sparing compared to the original internal target volume (ITV)-based clinical plan, while maintaining prescribed tumor coverage. The dose-sparing improvements were: Esophagus Dmax 50%, Heart Dmax 42% and Spinal cord Dmax 25%. Conclusion: Our early prototype system demonstrates that through massive parallelization, computationally intense tasks such as 4D treatment planning can be accomplished in clinically feasible timeframes. With further optimization, such systems are expected to enable the eventual clinical translation of higher-dimensional and complex treatment planning strategies to significantly improve plan quality. This work was partially supported through research funding from National Institutes of Health (R01CA169102) and Varian Medical Systems, Palo Alto, CA, USA.« less

Biological Applications and Effects of Optical Masers

DTIC Science & Technology

1988-02-19

LANDOLT RING SYSTEM 8-10 8. EARLY STUDIES ON SOLAR RADIATION AS A RETINAL HAZARD 10-15 9. RETINAL LIGHT TOXICITY AS A FUNCTION OF WAVE’.ENGTH 15-16 10...providing a simulated solor spectrum and 10 nm bandwidths throughout the near ultraviolet, visible and near infrared spectrum. This early ocular...do not present an ocular hazard at the levels used by the MILES prototype system or in fiber optic communication systems . By 1966 enough burn

The use of the intraooperative ozone - theraphy as prophylaxis of infections in surgery of locomotor system with special regard to total hip plasty - a preliminary study.

PubMed

Białoszewski, Dariusz

2003-12-30

Background. Ozone therapy - i.e. the treatment of patients by a mixture of oxygen and ozone - has been used for many years as a method ancillary to basic treatment, especially in those cases in which traditional treatment methods do not give satisfactory results. As it is widely known, ozone has antiseptic properties, specially on bacteria, ozone therapy has been used as a method of safeguarding tissues intraoperatively against infection with pathogenic hospital bacteria.
Material and methods. The investigation was carried out in the Chair and Department of Orthopedics and Traumatology of the Locomotor System at the Medical University in Warsaw. For investigative procedures a prototype of apparatus for intraoperative ozone therapy was built and own method of administration of ozone was devised. The Bioethics Commission of the Medical University in Warsaw agreed to the proposed procedures. From 3rd June to November 2003 this technique was administered to 83 patients who underwent total hip plasty with and without cement. The control group contained 80 patients who underwent similar procedures in 2003 without ozone therapy prophylaxis.
Results. No negative influence of the technique was observed during operative procedure. No adverse effects were observed in patients i.e.: wound inflammation, increase of postoperative pain, latency to early rehabilitation and elongation of hospital stay. In the observed group no septic complications were noted.
The evaluated prototype received a sympathetic reaction from the surgeons and middle medical staff. Troubleshooting of the prototype was minor and mainly due to misuse of the prototype.
After preliminary investigation we can state that the prototype is safe to the patients and user-friendly to the medical staff.
In the control group of 80 hip plasty two early septic complications were observed. The observation time of both groups was 4.6 months mean.
Conclusions. The usefulness of the proposed technique of ozone therapy in prophylaxis of early septic complications after elective orthopedic reconstructive surgery in which long tissue exposition and use of implants takes place still needs further clinical investigation.
Complex evaluation of the above mentioned technique and therapeutic efficacy of the proposed apparatus must have long term results, which is possible after minimum 12 months from the finish of each surgical procedure. This is especially true to the evaluation of patients who underwent joint realloplasty, in whom routinely taken biomaterial in the initiate procedure contained pathogens (without any clinical signs of infection).

Early Silurian Foraminifera from Gondwana - an early origin of the multichambered globothalamids?

NASA Astrophysics Data System (ADS)

Kaminski, Michael

2017-04-01

Early Silurian foraminifera until now have been regarded to consist of simple single-chambered monothalamids and two-chambered tubothalamids with an agglutinated wall. Although pseudo-multichambered agglutinated foraminifera first appeared in the mid-Ordovician (Kaminski et al. 2009), the origin of true multichambered forms was not believed to have taken place until the early or middle Devonian at the earliest (Holcová, 2002). New discoveries from the Lower Silurian Qusaiba Shale Member in Saudi Arabia point to an earlier origin of the multichambered globothalamid Foraminifera than the currently accepted estimate of 350 Ma (Pawlowski et al. 2003). The agglutinated foraminiferal genera Ammobaculites and Sculptobaculites have been recovered from dark graptolite-bearing claystones of Telychian age, from the transitional facies between the Qusaiba and Sharawa Members of the Qasim Formation at the type locality near Qusaiba town, Saudi Arabia. The multichambered lituolids occur as rare components in a foraminiferal assemblage consisting mostly of monothalamids. This new finding revises our understanding of the early evolution of the multichambered globothalamid foraminifera. The fossil record now shows that the globothalamids were already present in Gondwana by 435 m.y. Holcová, K. 2002. Silurian and Devonian foraminifers and other acid-resistant microfossils from the Barrandian area. Acta Musei Nationalis Pragae, Series B, Historia Naturalis, 58 (3-4), 83-140. Kaminski, M.A., Henderson, A.S., Cetean, C.G. & Waskowska-Oliwa, A. 2009. A new family of agglutinated foraminifera: the Ammolagenidae n.fam., and the evolution of multichambered tests. Micropaleontology, 55 (5), 487-494. Pawlowski, J., Holzmann, M., Berney, C., Fahrni, J.F., Gooday, Aj., Cedhagen, T., Habura, A., & Bowser, SS. 2003. The evolution of early Foraminifera. Proceedings of the National Academy of Sciences, 100 (20), 11494-11498

Meteor Impact Model in the new Space Power Chambers

NASA Image and Video Library

1962-09-21

S-65 Meteor Impact Model set up in the former Altitude Wind Tunnel at the National Aeronautics and Space Administration (NASA) Lewis Research Center just days after the September 12, 1962 rededication of the facility as the Space Power Chamber. Although larger test chambers would later be constructed, the rapid conversion of the wind tunnel into two space tanks allowed the facility to play a vital role in the early years of the space program. The eastern section of the tunnel, seen here became a vacuum chamber capable of simulating 100 miles altitude. This space tank was envisioned for the study of small satellites like this one. The transfer of the Centaur Program to Lewis one month late, however, permanently changed this mission. NASA was undertaking an in depth study at the time on the effect of micrometeoroids on satellites. Large space radiators were particularly vulnerable to damage from the small particles of space debris. In order to determine the hazard from meteoroids researchers had to define the flux rate relative to the mass and the velocity distribution because the greater the mass or the velocity of a meteoroid the greater the damage.

Fabrication of High Thermal Conductivity NARloy-Z-Diamond Composite Combustion Chamber Liner for Advanced Rocket Engines

NASA Technical Reports Server (NTRS)

Bhat, Biliyar N.; Greene, Sandra E.; Singh, Jogender

2016-01-01

This paper describes the process development for fabricating a high thermal conductivity NARloy-Z-Diamond composite (NARloy-Z-D) combustion chamber liner for application in advanced rocket engines. The fabrication process is challenging and this paper presents some details of these challenges and approaches used to address them. Prior research conducted at NASA-MSFC and Penn State had shown that NARloy-Z-40%D composite material has significantly higher thermal conductivity than the state of the art NARloy-Z alloy. Furthermore, NARloy-Z-40 %D is much lighter than NARloy-Z. These attributes help to improve the performance of the advanced rocket engines. Increased thermal conductivity will directly translate into increased turbopump power, increased chamber pressure for improved thrust and specific impulse. Early work on NARloy-Z-D composites used the Field Assisted Sintering Technology (FAST, Ref. 1, 2) for fabricating discs. NARloy-Z-D composites containing 10, 20 and 40vol% of high thermal conductivity diamond powder were investigated. Thermal conductivity (TC) data. TC increased with increasing diamond content and showed 50% improvement over pure copper at 40vol% diamond. This composition was selected for fabricating the combustion chamber liner using the FAST technique.

DDD versus VVIR pacing in patients, ages 70 and over, with complete heart block.

PubMed

Ouali, Sana; Neffeti, Elyes; Ghoul, Karima; Hammas, Sami; Kacem, Slim; Gribaa, Rim; Remedi, Fahmi; Boughzela, Essia

2010-05-01

Dual-chamber pacing is believed to have an advantage over single-chamber ventricular pacing. The aim of the study was to determine whether elderly patients with implanted pacemaker for complete atrioventricular block gain significant benefit from dual-chamber (DDD) compared with single-chamber ventricular demand (VVIR). The study was designed as a double-blind randomized two-period crossover study-each pacing mode was maintained for 3 months. Thirty patients (eight men, mean age 76.5 +/- 4.3 years) with implanted PM were submitted to a standard protocol, which included an interview, functional class assessment, quality of life (QoL) questionnaires, 6-minute walk test, and transthoracic echocardiographic examinations. QoL was measured by the SF-36. All these parameters were obtained on DDD mode pacing and VVIR mode pacing. Paired data were compared. QoL was significantly different between the two groups and showed the best values in DDD. Overall, no patient preferred VVIR mode, 18 preferred DDD mode, and 12 expressed no preference. No differences in mean walking distances were observed between patients with single-chamber and dual-chamber pacing. VVI pacing elicited marked decrease in left ventricle ejection fraction and significant enlargement of the left atrium. DDD pacing resulted in significant increase of the peak systolic velocities in lateral mitral annulus and septal mitral annulus. Early diastolic velocities on both sides of mitral annulus did not change. In active elderly patients with complete heart block, DDD pacing is associated with improved quality of life and systolic ventricular function compared with VVI pacing.

Modernized Approach for Generating Reproducible Heterogeneity Using Transmitted-Light for Flow Visualization Experiments

NASA Astrophysics Data System (ADS)

Jones, A. A.; Holt, R. M.

2017-12-01

Image capturing in flow experiments has been used for fluid mechanics research since the early 1970s. Interactions of fluid flow between the vadose zone and permanent water table are of great interest because this zone is responsible for all recharge waters, pollutant transport and irrigation efficiency for agriculture. Griffith, et al. (2011) developed an approach where constructed reproducible "geologically realistic" sand configurations are deposited in sandfilled experimental chambers for light-transmitted flow visualization experiments. This method creates reproducible, reverse graded, layered (stratified) thin-slab sand chambers for point source experiments visualizing multiphase flow through porous media. Reverse-graded stratification of sand chambers mimic many naturally occurring sedimentary deposits. Sandfilled chambers use light as nonintrusive tools for measuring water saturation in two-dimensions (2-D). Homogeneous and heterogeneous sand configurations can be produced to visualize the complex physics of the unsaturated zone. The experimental procedure developed by Griffith, et al. (2011) was designed using now outdated and obsolete equipment. We have modernized this approach with new Parker Deadel linear actuator and programed projects/code for multiple configurations. We have also updated the Roper CCD software and image processing software with the latest in industry standards. Modernization of transmitted-light source, robotic equipment, redesigned experimental chambers, and newly developed analytical procedures have greatly reduced time and cost per experiment. We have verified the ability of the new equipment to generate reproducible heterogeneous sand-filled chambers and demonstrated the functionality of the new equipment and procedures by reproducing several gravity-driven fingering experiments conducted by Griffith (2008).

Experimental Whole-Ecosystem Warming Alters Vegetation Phenology in a Boreal Spruce Bog: Initial Results from the SPRUCE Experiment

NASA Astrophysics Data System (ADS)

Richardson, A. D.

2016-12-01

Phenology is one of the most robust indicators of the biological impacts of global change. However, the response of phenology to future environmental conditions still remains highly uncertain because of the challenges associated with conducting realistic manipulative experiments. At the SPRUCE (Spruce and Peatland Responses Under Climatic and Environmental Change) experiment in the north-central United States, experimental temperature (0 to +9°C above ambient) and CO2 (ambient and elevated) treatments are being applied to mature, and intact, Picea mariana-Sphagnum spp. bog communities in their native habitat through the use of ten large (approximately 12 m wide, 10 m high) open-topped enclosures. We are tracking vegetation green-up and senescence in these chambers using repeat digital photography. Within each chamber, images are recorded every 30 minutes and uploaded to PhenoCam (http://phenocam.sr.unh.edu), where processed to yield quantitative measures of canopy color. These data are complemented by on-the-ground phenological data collected by human observers. Air warming treatments at SPRUCE began in August 2015. We observed a delay in senescence during autumn 2015 (2-5 days per degree of warming) and an advance in onset during spring 2016 (1-4 days per degree of warming). These patterns are robust across species and methods of phenological observation (i.e. camera-based vs. human observer). And, our results show very little evidence for photoperiod acting as a constraint on the response to warming. Early spring onset and consequent loss of frost hardiness in the warmest chambers proved disadvantageous when a brief period of extreme cold (to -12°C in the control chambers, to -3°C in the +9°C chambers) followed a month of generally mild weather. Foliage mortality for both Larix and Picea was immediate and severe, although both species subsequently re-flushed. These results give support for the hypothesis that warming may enhance the likelihood of spring frost damage. The SPRUCE experiment will run through 2025. We anticipate that different results may be obtained for autumn in future years, if early spring onset enhances evapotranspiration to a degree sufficient to cause drought conditions by late summer.

Effect of headspace mixing in static chambers and sampling protocol on calculated CH4 fluxes from soils

NASA Astrophysics Data System (ADS)

Juszczak, R.; Pihlatie, M.; Christiansen, J. R.; Giebels, M.; Schreiber, P.; Aaltonen, H.; Korhonen, J.; Rasilo, T.; Chojnicki, B. H.; Urbaniak, M.

2009-04-01

Closed static chambers are often used for greenhouse gas flux measurements from soils. The type of chamber, chamber handling and sampling protocol can influence the measurements. In most cases the calculated fluxes are suspected to be underestimated mainly because of reduction of gas diffusion from the soil to chamber headspace due to changed trace gas concentration gradient. Thus, fans are often applied to obtain better mixing of the air inside the chamber headspace and in turn reduce the negative effect of decreased concentration gradient. The open question is, however, to which extent the fluxes are changed by fans and whether they still remain underestimated or may even be overestimated? On the other hand, different sampling protocols are used assuming that they do not affect the flux measurements. To test different types of static chambers and different sampling procedures applied for measurement of greenhouse gas (CH4 and N2O) fluxes a chamber calibration campaign was organized at Hyytiälä Forestry Field Station in Southern Finland during August-October 2008. The main aim of the campaign was to quantitatively assess the uncertaintities and errors related to static chamber measurements. During this campaign static chambers were tested for 5 different CH4 and N2O flux levels with 3 different soil conditions (moisture and porosity) in a calibration tank described by Pumpanen et al. (2004). Among the different experiments, several special tests were carried out with the closed static chambers. Here, results of two special tests are presented to document whether 1) the air mixing inside the chamber headspace, 2) different sampling procedures influence the CH4 fluxes, and 3) how different calculation methods lead to varying results. Two static chambers of different volumes (65.5 and 195 liters) but with the same circular shape and surface area were connected to a LOS GATOS fats methane analyzer. The CH4 concentration inside the chamber headspace was monitored continuously with 1Hz frequency. Additionally, two different manual samplings procedures were tested and gas samples from chamber headspace were taken for gas chromatograph (GC) and analysed in two different laboratories. Gas concentrations in the calibration tank were monitored with a GC and an automatic gas analyzer (INNOVA). The preliminary results showed that air mixing inside the chamber headspace, the way of chamber handling and sampling procedures could have pronounced influence on the trace gas concentration detection inside a chamber, and as a consequence the calculated chamber fluxes. The moment of chamber enclosure can lead to a rapid increase in CH4 concentration due to a pressure effect in the chambers without a vent tube. Thus, it is essential to critically estimate the time of the first sampling so that it is early enough after chamber enclosure, but not disturbed by the initial chamber handling. It was also observed that manual sampling of gas can change the CH4 concentration in the chamber headspace. When mixing the chamber headspace air by a syringe, the subsequent gas sampling in the syringe may affect the diffusion of gas between the soil and the chamber headspace, and hence affect the calculated fluxes. It was observed that mixing the chamber headspace with a fan instead of syringes, reduced this effect during the chamber enclosure. Overall, fluxes measured with chamber equipped with a fan always gave higher fluxes (up to 40%) as compared to fluxes measured from chambers without a fan. Results of our experiment lead to the assumption that these differences were generally larger the higher the chamber was, the less porous the soil was, and the higher the fluxes were. We conclude from our experiment that static chambers used for greenhouse gas flux measurements should be equipped with at least one fan and a vent tube to increase mixing and reduce pressure propagation in the chamber-soil system, and that special attention should be paid to the handling of the chamber and to the timing of the gas sampling. References: Pumpanen, J., Kolari, P., Ilvesniemi, H., Minkkinen, K., Vesala, T., Niinistö, S., Lohila, A., Larmola, T., Morero, M., Pihlatie, M., Janssens, I., Curiel Yuste, J., Grünzweig, J. M., Reth, S., Subke, J.-A., Savage, K., Kutsch, W., Østreng, G., Ziegler, W., Anthoni, P., Lindroth, A. & Hari, P. 2004. Comparison of different chamber techniques for measuring soil CO2 efflux. Agricultural and Forest Meteorology 123, 159-176.

IMPACT OF O3 ON LEAF CONSTRUCTION COST AND CARBON ISOTOPE DISCRIMINATION

EPA Science Inventory

Plant response to ozone (O3) is controlled by the interactive balance between avoidance and intolerance processes. ush bean (Phaseolus vulgaris L.) plants were exposed to O3 in open-top field-exposure chambers in early and late season studies at Corvallis, Oregon. lants were grow...

9 CFR 313.5 - Chemical; carbon dioxide.

Code of Federal Regulations, 2010 CFR

2010-01-01

... accordance with this section so as to produce surgical anesthesia in the animals before they are shackled... accomplish the anesthesia quickly and calmly, with a minimum of excitement and discomfort to the animals. In... the anesthesia chamber is essential since the induction, or early phase, of anesthesia is less violent...

9 CFR 313.5 - Chemical; carbon dioxide.

Code of Federal Regulations, 2011 CFR

2011-01-01

... accordance with this section so as to produce surgical anesthesia in the animals before they are shackled... accomplish the anesthesia quickly and calmly, with a minimum of excitement and discomfort to the animals. In... the anesthesia chamber is essential since the induction, or early phase, of anesthesia is less violent...

A New In Vitro Model of Breast Cancer Metastasis to Bone

DTIC Science & Technology

2009-04-01

videomicroscopy [11, 12] have revealed that early stage, pre-angiogenic interactions between the cancer cells and the bone environment are crucial regulators of...1995) Steps in tumor metastasis: new concepts from intravital videomicroscopy . Cancer Metastasis Rev 14:279–301. doi:10.1007/BF00690599 12. Chambers AF

A New In Vitro Model of Breast Cancer Metastasis to Bone

DTIC Science & Technology

2008-04-01

intravital videomicroscopy [11, 12] have revealed that early stage, pre-angiogenic interactions between the cancer cells and the bone environment are...Chambers AF, MacDonald IC, Schmidt EE, et al. (1995) Steps in tumor metastasis: New concepts from intravital videomicroscopy . 279 - 301 13. Steeg PS

Oxygen isotope study of the Long Valley magma system, California: isotope thermometry and convection in large silicic magma bodies

NASA Astrophysics Data System (ADS)

Bindeman, Ilya; Valley, John

2002-07-01

Products of voluminous pyroclastic eruptions with eruptive draw-down of several kilometers provide a snap-shot view of batholith-scale magma chambers, and quench pre-eruptive isotopic fractionations (i.e., temperatures) between minerals. We report analyses of oxygen isotope ratio in individual quartz phenocrysts and concentrates of magnetite, pyroxene, and zircon from individual pumice clasts of ignimbrite and fall units of caldera-forming 0.76 Ma Bishop Tuff (BT), pre-caldera Glass Mountain (2.1-0.78 Ma), and post-caldera rhyolites (0.65-0.04 Ma) to characterize the long-lived, batholith-scale magma chamber beneath Long Valley Caldera in California. Values of δ18O show a subtle 1‰ decrease from the oldest Glass Mountain lavas to the youngest post-caldera rhyolites. Older Glass Mountain lavas exhibit larger ( 1‰) variability of δ18O(quartz). The youngest domes of Glass Mountain are similar to BT in δ18O(quartz) values and reflect convective homogenization during formation of BT magma chamber surrounded by extremely heterogeneous country rocks (ranging from 2 to +29‰). Oxygen isotope thermometry of BT confirms a temperature gradient between "Late" (815 °C) and "Early" (715 °C) BT. The δ18O(quartz) values of "Early" and "Late" BT are +8.33 and 8.21‰, consistent with a constant δ18O(melt)=7.8+/-0.1‰ and 100 °C temperature difference. Zircon-melt saturation equilibria gives a similar temperature range. Values of δ18O(quartz) for different stratigraphic units of BT, and in pumice clasts ranging in pre-eruptive depths from 6 to 11 km (based on melt inclusions), and document vertical and lateral homogeneity of δ18O(melt). Worldwide, five other large-volume rhyolites, Lava Creek, Lower Bandelier, Fish Canyon, Cerro Galan, and Toba, exhibit equal δ18O(melt) values of earlier and later erupted portions in each of the these climactic caldera-forming eruptions. We interpret the large-scale δ18O homogeneity of BT and other large magma chambers as evidence of their longevity (>105 years) and convection. However, remaining isotopic zoning in some quartz phenocrysts, trace element gradients in feldspars, and quartz and zircon crystal size distributions are more consistent with far shorter timescales (102-104 years). We propose a sidewall-crystallization model that promotes convective homogenization, roofward accumulation of more evolved and stagnant, volatile-rich liquid, and develops compositional and temperature gradients in pre-climactic magma chamber. Crystal + melt + gas bubbles mush near chamber walls of variable δ18O gets periodically remobilized in response to chamber refill by new hotter magmas. One such episode of chamber refill by high-Ti, Sr, Ba, Zr, and volatile-richer magma happened 103-104 years prior to the 0.76-Ma caldera collapse that caused magma mixing at the base, mush thawing near the roof and walls, and downward settling of phenocrysts into this hybrid melt.

Designing a Digital Instructional Management System To Optimize Early Education.

ERIC Educational Resources Information Center

Mooij, Ton

2002-01-01

Discusses digital instructional management systems (DIMSs) and describes a pilot study conducted in two Dutch kindergartens with a prototype DIMS that included individualization and optimization, that is matching curriculum with learner characteristics. Topics include learning processes for children at risk; and future plans. (LRW)

Information Retrieval (SPIRES) and Library Automation (BALLOTS) at Stanford University.

ERIC Educational Resources Information Center

Ferguson, Douglas, Ed.

At Stanford University, two major projects have been involved jointly in library automation and information retrieval since 1968: BALLOTS (Bibliographic Automation of Large Library Operations) and SPIRES (Stanford Physics Information Retrieval System). In early 1969, two prototype applications were activated using the jointly developed systems…

Adaptation of the Estuarine Fish, Fundulus heterclitus (Atlantic Killifish) to Polychlorinated Biphenyls (PCBs)

EPA Science Inventory

To characterize intra-specific variation in sensitivity to highly toxic pollutants in the non-migratory estuarine Atlantic killifish (Fundulus heteroclitus), we compared early life stage responses to the prototypical dioxin-like compound, 3,3’4,4’,5 hexachlorobiphenyl (PCB126). ...

Ultra-Wideband Time-Difference-of-Arrival High Resolution 3D Proximity Tracking System

NASA Technical Reports Server (NTRS)

Ni, Jianjun; Arndt, Dickey; Ngo, Phong; Phan, Chau; Dekome, Kent; Dusl, John

2010-01-01

This paper describes a research and development effort for a prototype ultra-wideband (UWB) tracking system that is currently under development at NASA Johnson Space Center (JSC). The system is being studied for use in tracking of lunar./Mars rovers and astronauts during early exploration missions when satellite navigation systems are not available. U IATB impulse radio (UWB-IR) technology is exploited in the design and implementation of the prototype location and tracking system. A three-dimensional (3D) proximity tracking prototype design using commercially available UWB products is proposed to implement the Time-Difference- Of-Arrival (TDOA) tracking methodology in this research effort. The TDOA tracking algorithm is utilized for location estimation in the prototype system, not only to exploit the precise time resolution possible with UWB signals, but also to eliminate the need for synchronization between the transmitter and the receiver. Simulations show that the TDOA algorithm can achieve the fine tracking resolution with low noise TDOA estimates for close-in tracking. Field tests demonstrated that this prototype UWB TDOA High Resolution 3D Proximity Tracking System is feasible for providing positioning-awareness information in a 3D space to a robotic control system. This 3D tracking system is developed for a robotic control system in a facility called "Moonyard" at Honeywell Defense & System in Arizona under a Space Act Agreement.

A user-centred design process of new cold-protective clothing for offshore petroleum workers operating in the Barents Sea

PubMed Central

NAESGAARD, Ole Petter; STORHOLMEN, Tore Christian Bjørsvik; WIGGEN, Øystein Nordrum; REITAN, Jarl

2017-01-01

Petroleum operations in the Barents Sea require personal protective clothing (PPC) to ensure the safety and performance of the workers. This paper describes the accomplishment of a user-centred design process of new PPC for offshore workers operating in this area. The user-centred design process was accomplished by mixed-methods. Insights into user needs and context of use were established by group interviews and on-the-job observations during a field-trip. The design was developed based on these insights, and refined by user feedback and participatory design. The new PPC was evaluated via field-tests and cold climate chamber tests. The insight into user needs and context of use provided useful input to the design process and contributed to tailored solutions. Providing users with clothing prototypes facilitated participatory design and iterations of design refinement. The group interviews following the final field test showed consensus of enhanced user satisfaction compared to PPC in current use. The final cold chamber test indicated that the new PPC provides sufficient thermal protection during the 60 min of simulated work in a wind-chill temperature of −25°C. Conclusion: Accomplishing a user-centred design process contributed to new PPC with enhanced user satisfaction and included relevant functional solutions. PMID:29046494

A user-centred design process of new cold-protective clothing for offshore petroleum workers operating in the Barents Sea.

PubMed

Naesgaard, Ole Petter; Storholmen, Tore Christian Bjørsvik; Wiggen, Øystein Nordrum; Reitan, Jarl

2017-12-07

Petroleum operations in the Barents Sea require personal protective clothing (PPC) to ensure the safety and performance of the workers. This paper describes the accomplishment of a user-centred design process of new PPC for offshore workers operating in this area. The user-centred design process was accomplished by mixed-methods. Insights into user needs and context of use were established by group interviews and on-the-job observations during a field-trip. The design was developed based on these insights, and refined by user feedback and participatory design. The new PPC was evaluated via field-tests and cold climate chamber tests. The insight into user needs and context of use provided useful input to the design process and contributed to tailored solutions. Providing users with clothing prototypes facilitated participatory design and iterations of design refinement. The group interviews following the final field test showed consensus of enhanced user satisfaction compared to PPC in current use. The final cold chamber test indicated that the new PPC provides sufficient thermal protection during the 60 min of simulated work in a wind-chill temperature of -25°C. Accomplishing a user-centred design process contributed to new PPC with enhanced user satisfaction and included relevant functional solutions.

Analysis of high mass resolution PTR-TOF mass spectra from 1,3,5-trimethylbenzene (TMB) environmental chamber experiments

NASA Astrophysics Data System (ADS)

Müller, M.; Graus, M.; Wisthaler, A.; Hansel, A.; Metzger, A.; Dommen, J.; Baltensperger, U.

2011-09-01

A series of 1,3,5-trimethylbenzene (TMB) photo-oxidation experiments was performed in the 27-m3 Paul Scherrer Institute environmental chamber under various NOx conditions. A University of Innsbruck prototype high resolution Proton Transfer Reaction Time-of-Flight Mass Spectrometer (PTR-TOF) was used for measurements of gas and particulate phase organics. The gas phase mass spectrum displayed ~200 ion signals during the TMB photo-oxidation experiments. Molecular formulas CNmHnNoOp were determined and ion signals were separated and grouped according to their C, O and N numbers. This allowed to determine the time evolution of the O:C ratio and of the average carbon oxidation state OSC of the reaction mixture. Both quantities were compared with master chemical mechanism (MCMv3.1) simulations. The O:C ratio in the particle phase was about twice the O:C ratio in the gas phase. Average carbon oxidation states of secondary organic aerosol (SOA) samples OSCSOA were in the range of -0.34 to -0.31, in agreement with expected average carbon oxidation states of fresh SOA (OSC = -0.5 - 0).

Analysis of high mass resolution PTR-TOF mass spectra from 1,3,5-trimethylbenzene (TMB) environmental chamber experiments

NASA Astrophysics Data System (ADS)

Müller, M.; Graus, M.; Wisthaler, A.; Hansel, A.; Metzger, A.; Dommen, J.; Baltensperger, U.

2012-01-01

A series of 1,3,5-trimethylbenzene (TMB) photo-oxidation experiments was performed in the 27-m3 Paul Scherrer Institute environmental chamber under various NOx conditions. A University of Innsbruck prototype high resolution Proton Transfer Reaction Time-of-Flight Mass Spectrometer (PTR-TOF) was used for measurements of gas and particulate phase organics. The gas phase mass spectrum displayed ~200 ion signals during the TMB photo-oxidation experiments. Molecular formulas CmHnNoOp were determined and ion signals were separated and grouped according to their C, O and N numbers. This allowed to determine the time evolution of the O:C ratio and of the average carbon oxidation state OSC of the reaction mixture. Both quantities were compared with master chemical mechanism (MCMv3.1) simulations. The O:C ratio in the particle phase was about twice the O:C ratio in the gas phase. Average carbon oxidation states of secondary organic aerosol (SOA) samples OSCSOA were in the range of -0.34 to -0.31, in agreement with expected average carbon oxidation states of fresh SOA (OSC = -0.5-0).

Design and efficacy of a single-use bioreactor for heart valve tissue engineering.

PubMed

Converse, Gabriel L; Buse, Eric E; Neill, Kari R; McFall, Christopher R; Lewis, Holley N; VeDepo, Mitchell C; Quinn, Rachael W; Hopkins, Richard A

2017-02-01

Heart valve tissue engineering offers the promise of improved treatments for congenital heart disorders; however, widespread clinical availability of a tissue engineered heart valve (TEHV) has been hindered by scientific and regulatory concerns, including the lack of a disposable, bioreactor system for nondestructive valve seeding and mechanical conditioning. Here we report the design for manufacture and the production of full scale, functional prototypes of such a system. To evaluate the efficacy of this bioreactor as a tool for seeding, ovine aortic valves were decellularized and subjected to seeding with human mesenchymal stem cells (hMSC). The effects of pulsatile conditioning using cyclic waveforms tuned to various negative and positive chamber pressures were evaluated, with respect to the seeding of cells on the decellularized leaflet and the infiltration of seeded cells into the interstitium of the leaflet. Infiltration of hMSCs into the aortic valve leaflet was observed following 72 h of conditioning under negative chamber pressure. Additional conditioning under positive pressure improved cellular infiltration, while retaining gene expression within the MSC-valve interstitial cell phenotype lineage. This protocol resulted in a subsurface pilot population of cells, not full tissue recellularization. © 2015 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 105B: 249-259, 2017. © 2015 Wiley Periodicals, Inc.

Prototype Development of an Implantable Compliance Chamber for a Total Artificial Heart.

PubMed

Schmitz, Stephanie; Unthan, Kristin; Sedlaczek, Marc; Wald, Felix; Finocchiaro, Thomas; Spiliopoulos, Sotirios; Koerfer, Reiner; Steinseifer, Ulrich

2017-02-01

At our institute a total artificial heart is being developed. It is directly actuated by a linear drive in between two ventricles, which comprise membranes to separate the drive and blood flow. A compliance chamber (CC) is needed to reduce pressure peaks in the ventricles and to increase the pump capacity. Therefore, the movement of the membrane is supported by applying a negative pressure to the air volume inside the drive unit. This study presents the development of the implantable CC which is connected to the drive unit of the total artificial hearts (TAH). The anatomical fit of the CC is optimized by analyzing CT data and adapting the outer shape to ensure a proper fit. The pressure peaks are reduced by the additional volume and the flexible membrane of the CC. The validation measurements of change in pressure peaks and flow are performed using the complete TAH system connected to a custom mock circulation loop. Using the CC, the pressure peaks could be damped below 5 mm Hg in the operational range. The flow output was increased by up to 14.8% on the systemic side and 18.2% on the pulmonary side. The described implantable device can be used for upcoming chronic animal trials. © 2016 International Center for Artificial Organs and Transplantation and Wiley Periodicals, Inc.

NiAl Coatings Investigated for Use in Reusable Launch Vehicles

NASA Technical Reports Server (NTRS)

Raj, Sai V.; Ghosn, Louis J.; Barrett, Charles A.

2003-01-01

As part of its major investment in the area of advanced space transportation, NASA is developing new technologies for use in the second- and third-generation designs of reusable launch vehicles. Among the prototype rocket engines being considered for these launch vehicles are those designed to use liquid hydrogen as the fuel and liquid oxygen as the oxidizer. Advanced copper alloys, such as copper-chromium-niobium (Cu-8(at.%)Cr- 4(at.%)Nb, also referred to as GRCop-84), which was invented at the NASA Glenn Research Center, are being considered for use as liner materials in the combustion chambers and nozzle ramps of these engines. However, previous experience has shown that, in rocket engines using liquid hydrogen and liquid oxygen, copper alloys are subject to a process called blanching, where the material undergoes environmental attack under the action of the combustion gases. In addition, the copper alloy liners undergo thermomechanical fatigue, which often results in an initially square cooling channel deforming into a dog-house shape. Clearly, there is an urgent need to develop new coatings to protect copper liners from environmental attack inside rocket chambers and to lower the temperature of the liners to reduce the probability of deformation and failure by thermomechanical fatigue.

Using three-dimensional rapid prototyping in the design and development of orthopaedic screws in standardised pull-out tests.

PubMed

Leslie, Laura Jane; Connolly, Ashley; Swadener, John G; Junaid, Sarah; Theivendran, Kanthan; Deshmukh, Subodh C

2018-06-01

The majority of orthopaedic screws are designed, tested and manufactured by existing orthopaedics companies and are predominantly developed with healthy bone in mind. The timescales and costs involved in the development of a new screw design, for example, for osteoporotic bone, are high. In this study, standard wood screws were used to analyse the concept of using three-dimensional printing, or rapid prototyping, as a viable stage of development in the design of a new bone screw. Six wood screws were reverse engineered and printed in polymeric material using stereolithography. Three of the designs were also printed in Ti6Al4V using direct metal laser sintering; however, these were not of sufficient quality to test further. Both the original metal screws (metal) and polymeric rapid prototyping screws were then tested using standard pull-out tests from low-density polyurethane blocks (Sawbones). Results showed the highest pull-out strengths for screws with the longest thread length and the smallest inner diameter. Of the six screw designs tested, five showed no more than a 17% variance between the metal and rapid prototyping results. A similar pattern of results was shown between the screw designs for both the metal and rapid prototyping screws in five of the six cases. While not producing fully comparable pull-out results to orthopaedic screws, the results from this study do provide evidence of the potential usefulness and cost-effectiveness of rapid prototyping in the early stages of design and testing of orthopaedic screws.

Serum of Blood Separation by Means of Dynamic Electrochromatography in a Centrifugal and Electromagnetic Gradient.

PubMed

Jan Dyszkiewicz, Andrzej

2014-01-01

The paper presents the dynamic association of several gradients of separation with electrophoresis and the laboratory implementation of a prototype device for dynamic electrochromatography in a centrifugal and electromagnetic gradient (DECGOE), based on patent PL171643. The object of the study was to compare the separation capacity and repeatability of the location of edge parameters (xx(1), yy(1), d) of the contours of a proteinogram fraction for conventional electrophoresis (EF), radial SR-DECGOE separation and three variants of radial-transverse SR-SPM, SR-SPE, SRSPRRM distribution as well as the reproducibility of the following prototype parameters: PV(1), PV(2), PV(3)[V] potentials, PV(3)[F] frequency, ω(1) and ω(2) rotational speed, MC mixer chamber buffer [pH] and volume[ml], and B [T] magnetic induction. Human blood serum was used in the study, 50 samples for each separation type. The highest rate of fraction formation was registered for the SR-SPRRM (8,07/s) variant. The percentage values of standard deviations for the edge parameters of proteinograms were the lowest for conventional electrophoresis (EF), slightly higher for radial distribution SR, while among the radial-transverse separations, the highest accuracy was obtained for the SR-SPRRM variant.

High speed superconducting flywheel system for energy storage

NASA Astrophysics Data System (ADS)

Bornemann, H. J.; Urban, C.; Boegler, P.; Ritter, T.; Zaitsev, O.; Weber, K.; Rietschel, H.

1994-12-01

A prototype of a flywheel system with auto stable high temperature superconducting bearings was built and tested. The bearings offered good vertical and lateral stability. A metallic flywheel disk, ø 190 mm x 30 mm, was safely rotated at speeds up to 15000 rpm. The disk was driven by a 3 phase synchronous homopolar motor/generator. Maximum energy capacity was 3.8 Wh, maximum power was 1.5 KW. The dynamic behavior of the prototype was tested, characterized and evaluated with respect to axial and lateral stiffness, decay torques (bearing drag), vibrational modes and critical speeds. The bearings supports a maximum weight of 65 N at zero gap, axial and lateral stiffness at 1 mm gap were 440 N/cm and 130 N/cm, respectively. Spin down experiments were performed to investigate the energy efficiency of the system. The decay rate was found to depend upon background pressure in the vacuum chamber and upon the gap width in the bearing. At a background pressure of 5x10 -4 Torr, the coefficient of friction (drag-to-lift ratio) was measured to be 0.000009 at low speeds for 6 mm gap width in the bearing. Our results indicate that further refinement of this technology will allow operation of higly efficient superconducting flywheels in the kWh range.

D Modelling and Rapid Prototyping for Cardiovascular Surgical Planning - Two Case Studies

NASA Astrophysics Data System (ADS)

Nocerino, E.; Remondino, F.; Uccheddu, F.; Gallo, M.; Gerosa, G.

2016-06-01

In the last years, cardiovascular diagnosis, surgical planning and intervention have taken advantages from 3D modelling and rapid prototyping techniques. The starting data for the whole process is represented by medical imagery, in particular, but not exclusively, computed tomography (CT) or multi-slice CT (MCT) and magnetic resonance imaging (MRI). On the medical imagery, regions of interest, i.e. heart chambers, valves, aorta, coronary vessels, etc., are segmented and converted into 3D models, which can be finally converted in physical replicas through 3D printing procedure. In this work, an overview on modern approaches for automatic and semiautomatic segmentation of medical imagery for 3D surface model generation is provided. The issue of accuracy check of surface models is also addressed, together with the critical aspects of converting digital models into physical replicas through 3D printing techniques. A patient-specific 3D modelling and printing procedure (Figure 1), for surgical planning in case of complex heart diseases was developed. The procedure was applied to two case studies, for which MCT scans of the chest are available. In the article, a detailed description on the implemented patient-specific modelling procedure is provided, along with a general discussion on the potentiality and future developments of personalized 3D modelling and printing for surgical planning and surgeons practice.

Design and Fabrication of a Composite Morphing Radiator Panel Using High Conductivity Fibers

NASA Technical Reports Server (NTRS)

Wescott, Matthew T.; McQuien, J. Scott; Bertagne, Christopher L.; Whitcomb, John D.; Hart, Darren J.; Erickson, Lisa R.

2017-01-01

Upcoming crewed space missions will involve large internal and external heat loads and require advanced thermal control systems to maintain a desired internal environment temperature. Radiators with at least 12:1 turndown ratios (the ratio between the maximum and minimum heat rejection rates) will be needed. However, current technologies are only able to achieve turndown ratios of approximately 3:1. A morphing radiator capable of altering shape could significantly increase turndown capabilities. Shape memory alloys offer qualities that may be well suited for this endeavor; their temperature-dependent phase changes could offer radiators the ability to passively control heat rejection. In 2015, a morphing radiator prototype was constructed and tested in a thermal vacuum environment, where it successfully demonstrated the morphing behavior and variable heat rejection. Newer composite prototypes have since been designed and manufactured using two distinct types of SMA materials. These models underwent temperature cycling tests in a thermal vacuum chamber and a series of fatigue tests to characterize the lifespan of these designs. The focus of this paper is to present the design approach and testing of the morphing composite facesheet. The discussion includes: an overall description of the project background, definition of performance requirements, composite materials selection, use of analytic and numerical design tools, facesheet fabrication, and finally fatigue testing with accompanying results.

Online measurement of fluence and position for protontherapy beams

NASA Astrophysics Data System (ADS)

Benati, C.; Boriano, A.; Bourhaleb, F.; Cirio, R.; Cirrone, G. A. P.; Cornelius, I.; Cuttone, G.; Donetti, M.; Garelli, E.; Giordanengo, S.; Guérin, L.; La Rosa, A.; Luparia, A.; Marchetto, F.; Martin, F.; Meyroneinc, S.; Peroni, C.; Pittà, G.; Raffaele, L.; Sabini, M. G.; Valastro, L.

2004-09-01

Tumour therapy with proton beams has been used for several decades in many centres with very good results in terms of local control and overall survival. Typical pathologies treated with this technique are located in head and neck, eye, prostate and in general at big depths or close to critical organs. The Experimental Physics Department of the University of Turin and the local Section of INFN, in collaboration with INFN Laboratori Nazionali del Sud Catania and Centre de Protontherapie de Orsay Paris, have developed detector systems that allow the measurement of beam position and fluence, obtained in real time during beam delivery. The centre in Catania (CATANA: Centro di AdroTerapia ed Applicazioni Nucleari Avanzate) has been treating patients with eye pathologies since spring 2002 using a superconducting cyclotron accelerating protons up to 62 MeV.This kind of treatments need high-resolution monitor systems and for this reason we have developed a 256-strip segmented ionisation chamber, each strip being 400 μm wide, with a total sensitive area 13×13 cm2. The Centre de Protontherapie de Orsay (CPO) has been operational since 1991 and features a synchrocyclotron used for eye and head and neck tumours with proton beams up to 200 MeV. The monitor system has to work on a large surface and for this purpose we have designed a pixel-segmented ionisation chamber, each pixel being 5×5 mm2, for a total active area of 16×16 cm2. The results obtained with two prototypes of the pixel and strip chambers demonstrate that the detectors allow the measurement of fluence and centre of gravity as requested by clinical specifications.

Cryogenic Hydrogen Fuel for Controlled Inertial Confinement Fusion (Cryogenic Target Factory Concept Based on FST-Layering Method)

NASA Astrophysics Data System (ADS)

Aleksandrova, I. V.; Koresheva, E. R.; Koshelev, I. E.; Krokhin, O. N.; Nikitenko, A. I.; Osipov, I. E.

2017-12-01

A central element of a power plant based on inertial confinement fusion (ICF) is a target with cryogenic hydrogen fuel that should be delivered to the center of a reactor chamber with a high accuracy and repetition rate. Therefore, a cryogenic target factory (CTF) is an integral part of any ICF reactor. A promising way to solve this problem consists in the FST layering method developed at the Lebedev Physical Institute (LPI). This method (rapid fuel layering inside moving free-standing targets) is unique, having no analogs in the world. The further development of FST-layering technologies is implemented in the scope of the LPI program for the creation of a modular CTF and commercialization of the obtained results. In this report, we discuss our concept of CTF (CTF-LPI) that exhibits the following distinctive features: using a FST-layering technology for the elaboration of an in-line production of cryogenic targets, using an effect of quantum levitation of high-temperature superconductors (HTSCs) in magnetic field for noncontacting manipulation, transport, and positioning of the free-standing cryogenic targets, as well as in using a Fourier holography technique for an on-line characterization and tracking of the targets flying into the reactor chamber. The results of original experimental and theoretical investigations performed at LPI indicate that the existing and developing target fabrication capabilities and technologies can be applied to ICF target production. The unique scientific, engineering, and technological base developed in Russia at LPI allows one to make a CTFLPI prototype for mass production of targets and delivery thereof at the required velocity into the ICF reactor chamber.

Volatiles Evolved from Soybean Products Intended for Use in Long Duration Space Missions

NASA Technical Reports Server (NTRS)

Vodovotz, Yael; Bourland, Charles T.

1999-01-01

Soybeans have been baselined to be grown in a habitat (Advanced Life Support Systems Integration Test Bed, ALSSITB) intended for evaluating advanced life support systems developed for long duration missions to the Moon or Mars. The ALSSITB is being constructed at NASA-Johnson Space Center and is composed of 5 chambers (4.6 m x 11.3 m each) and an airlock joined by an interconnecting tunnel (3.7 m x 19.2 m). Processed soy products such as soy milk and soy bread are planned to be incorporated into a nutritionally sound, plant-based food system. Since all consumables will be recycled and reused, volatile compounds evolved during the manufacturing of these food products need to be quantified to assess their impact on this closed loop system. Soy milk was made in a prototype machine and bread in a commercial bread baking machine. These machines were each placed in a tightly closed chamber and, at the completion of the process, air volatiles were identified and quantified by GC/MS. For soy milk, ethanol, acetaldehyde, methanol, hexanal, propanal and acetone and for soybread, acetaldehyde, ethanol, N-propanol and ethyl acetate were detected in significant quantities. The crew members will spend an average of 180 days in the ALSSITB and it was estimated that 138 batches of soy milk will be processed in the tunnel and 130 loaves of soybread would be baked in the habitat chamber during their stay. The aforementioned volatiles would surpass the 180 day Spacecraft Maximum Allowable Concentrations (SMACs) if no means of scrubbing are adapted which would lead to toxic levels of these compounds. Therefore, sufficient means for eliminating the contribution of volatiles evolved from food processing and preparation equipment needs to be provided in the ALSSITB.

Suitport Feasibility - Human Pressurized Space Suit Donning Tests with the Marman Clamp and Pneumatic Flipper Suitport Concepts

NASA Technical Reports Server (NTRS)

Boyle, Robert M.; Rodriggs, Liana; Allton, Charles; Jennings, Mallory; Aitchision, Lindsay

2013-01-01

The suitport concept has been recently implemented as part of the small pressurized lunar rover (Currently the Space Exploration vehicle, or SEV) and the Multi-Mission Space Exploration Vehicle (MMSEV) concept demonstrator vehicle. Suitport replaces or augments the traditional airlock function of a spacecraft by providing a bulkhead opening, capture mechanism, and sealing system to allow ingress and egress of a space suit while the space suit remains outside of the pressurized volume of the spacecraft. This presents significant new opportunities to EVA exploration in both microgravity and surface environments. The suitport concept will enable three main improvements in EVA by providing reductions in: pre-EVA time from hours to less than thirty minutes; airlock consumables; contamination returned to the cabin with the EVA crewmember. Two second generation suitports were designed and tested. The previously reported second generation Marman Clamp suitport and a newer concept, the Pneumatic Flipper Suitport. These second generation suitports demonstrated human donning and doffing of the Z1 spacesuit with an 8.3 psi pressure differential across the spacesuit. Testing was performed using the JSC B32 Chamber B, a human rated vacuum chamber. The test included human rated suitports, the suitport compatible prototype suit, and chamber modifications. This test brought these three elements together in the first ever pressurized donning of a rear entry suit through a suitport. This paper presents the results of the testing, including unexpected difficulties with doffing, and engineering solutions implemented to ease the difficulties. A review of suitport functions, including a discussion of the need to doff a pressurized suit in earth gravity, is included. Recommendations for future design and testing are documented.

Suitport Feasibility - Human Pressurized Space Suit Donning Tests with the Marmon Clamp and Pneumatic Flipper Suitport Concepts

NASA Technical Reports Server (NTRS)

Boyle, Robert M.; Rodriggs, Liana; Alton, Charles; Jennings, Mallory; Aitchison, Lindsay

2012-01-01

The suitport concept has been recently implemented as part of the small pressurized lunar rover (Currently the Space Exploration vehicle, or SEV) and the Multi-Mission Space Exploration Vehicle (MMSEV) concept demonstrator vehicle. Suitport replaces or augments the traditional airlock function of a spacecraft by providing a bulkhead opening, capture mechanism, and sealing system to allow ingress and egress of a space suit while the space suit remains outside of the pressurized volume of the spacecraft. This presents significant new opportunities to EVA exploration in both microgravity and surface environments. The suitport concept will enable three main improvements in EVA by providing reductions in: pre-EVA time from hours to less than thirty minutes; airlock consumables; contamination returned to the cabin with the EVA crewmember. Two second generation suitports were designed and tested. The previously reported second generation Marman Clamp suitport and a newer concept, the Pneumatic Flipper Suitport. These second generation suitports demonstrated human donning and doffing of the Z1 spacesuit with an 8.3 psi pressure differential across the spacesuit. Testing was performed using the JSC B32 Chamber B, a human rated vacuum chamber. The test included human rated suitports, the suitport compatible prototype suit, and chamber modifications. This test brought these three elements together in the first ever pressurized donning of a rear entry suit through a suitport. This paper presents the results of the testing, including unexpected difficulties with doffing, and engineering solutions implemented to ease the difficulties. A review of suitport functions, including a discussion of the need to doff a pressurized suit in earth gravity, is included. Recommendations for future design and testing are documented.

Chamber evaluation of a portable GC with tunable retention and microsensor-array detection for indoor air quality monitoring.

PubMed

Lu, Chia Jung; Jin, Chunguang; Zellers, Edward T

2006-02-01

The evaluation of a novel prototype instrument designed for on-site determinations of VOC mixtures found in indoor working environments is described. The instrument contains a miniature multi-stage preconcentrator, a dual-column separation module with pressure-tunable retention capabilities, and an integrated array of three polymer-coated surface acoustic wave sensors. It was challenged with dynamic test-atmospheres of a set of 15 common indoor air contaminants at parts-per-billion concentrations within a stainless-steel chamber under a range of conditions. Vapours were reliably identified at a known level of confidence by combining column retention times with sensor-array response patterns and applying a multivariate statistical test of pattern fidelity for the chromatographically resolved vapours. Estimates of vapour concentrations fell within 7% on average of those determined by EPA Method TO-17, and limits of detection ranged from 0.2 to 28 ppb at 25 degrees C for 1 L samples collected and analyzed in <12 min. No significant humidity effects were observed (0-90% RH). Increasing the chamber temperature from 25 to 30 degrees C reduced the retention times of the more volatile analytes which, in turn, demanded alterations in the scheduling of column-junction-point pressure (flow) modulations performed during the analysis. Reductions in sensor sensitivities with increasing temperature were predictable and similar among the sensors in the array such that most response patterns were not altered significantly. Short-term fluctuations in concentration were accurately tracked by the instrument. Results indicate that this type of instrument could provide routine, semi-autonomous, near-real-time, multi-vapour monitoring in support of efforts to assess air quality in office environments.

Performance of the CELSS Antarctic Analog Project (CAAP) Crop Production System

NASA Technical Reports Server (NTRS)

Bubenheim, David L.; Flynn, Michael T.; Bates, Maynard; Schlick, Greg; Kliss, Mark (Technical Monitor)

1998-01-01

Regenerative life support systems potentially offer a level of self-sufficiency and a concomitant decrease in logistics and associated costs in support of space exploration and habitation missions. Current state-of-the-art in plant based, regenerative life support requires resources in excess of resource allocations proposed for candidate mission scenarios. Feasibility thresholds have been identified for candidate exploration missions. The goal of this paper is to review recent advances in performance achieved in the CELSS Antarctic Analog Project (CAAP) in light of likely resource constraints. A prototype CAAP crop production chamber has been constructed and operated at the Ames Research Center. The chamber includes a number of unique hardware and software components focused on attempts to increase production efficiency, increase energy efficiency, and control the flow of energy and mass through the system to achieve enhanced performance efficiency. Both single crop, batch production, and continuous cultivation of mixed crops Product ion scenarios have been completed. The crop productivity as well as engineering performance of the chamber will be described. For each scenario, energy required and partitioned for lighting, cooling, pumps, fans, etc. is quantified. Crop production and the resulting lighting efficiency and energy conversion efficiencies are presented. In the mixed-crop scenario, with up to 25 different crops under cultivation, 17 sq m of crop area provided a mean of 515 g edible biomass per day (83% of the approximately 620 g required for one person). Lighting efficiency (moles on photons kWh-1) approached 4 and the conversion efficiency of light energy to biomass was greatly enhanced compared with conventional growing systems. Engineering and biological performance achieved place plant-based life support systems at the threshold of feasibility.

Quantification of wind flow in the European Mars Simulation Wind Tunnel Facility

NASA Astrophysics Data System (ADS)

Holstein-Rathlou, C.; Merrison, J. P.; Iversen, J. J.; Nornberg, P.

2012-04-01

We present the European Mars Simulation Wind Tunnel facility, a unique prototype facility capable of simulating a wide range of environmental conditions, such as those which can be found at the surface of Earth or Mars. The chamber complements several other large-scale simulation facilities at Aarhus University, Denmark. The facility consists of a 50 m3 environmental chamber capable of operating at low pressure (0.02 - 1000 mbar) and cryogenic temperatures (-130 °C up to +60 °C). This chamber houses a re-circulating wind tunnel capable of generating wind speeds up to 25 m/s and has a dust injection system that can produce suspended particulates (aerosols). It employs a unique LED based optical illumination system (solar simulator) and an advanced network based control system. Laser based optoelectronic instrumentation is used to quantify and monitor wind flow, dust suspension and deposition. This involves a commercial Laser Doppler Anemometer (LDA) and a Particle Dynamics Analysis receiver (PDA), which are small laser based instruments specifically designed for measuring wind speed and sizes of particles situated in a wind flow. Wind flow calibrations will be performed with the LDA system and presented. Pressure and temperature calibrations will follow in order to enable the facility to be used for the testing, development, calibration and comparison of e.g. meteorological sensors under a wide range of environmental conditions as well as multi-disciplinary scientific studies. The wind tunnel is accessible to international collaborators and space agencies for instrument testing, calibration and qualification. It has been financed by the European Space Agency (ESA) as well as the Aarhus University Science Faculty and the Villum Kann Rasmussen Foundation.

Research and Development on a Public Attitude Instrument for Stuttering

ERIC Educational Resources Information Center

St. Louis, Kenneth O.

2012-01-01

This paper summarizes research associated with the development of the "Public Opinion Survey of Human Attributes-Stuttering" ("POSHA-S"), a survey instrument designed to provide a worldwide standard measure of public attitudes toward stuttering. Pilot studies with early experimental prototypes of the "POSHA-S" are summarized that relate to…

Timing and tracking for the Crystal Barrel detector

NASA Astrophysics Data System (ADS)

Beck, Reinhard; Brinkmann, Kai; Novotny, Rainer

2017-01-01

The aim of the project D.3 is the upgrade of several detector components used in the CBELSA/TAPS experiment at ELSA. The readout of the Crystal Barrel Calorimeter will be extended by a timing branch in order to gain trigger capability for the detector, which will allow to measure completely neutral final states in photoproduction reactions (see projects A.1 and C.5). Additionally, the readout of the inner crystals of the TAPS detector, which covers the forward opening of the Crystal Barrel Calorimeter, will be modified to be capable of high event rates due to the intensity upgrade of ELSA. Furthermore, a full-scale prototype Time Projection Chamber (TPC) has been built to be used as a new central tracker for the CBELSA/TAPS experiment at ELSA and the FOPI experiment at GSI.

Development of the GEM-TPC X-ray Polarimeter with the Scalable Readout System

NASA Astrophysics Data System (ADS)

Kitaguchi, Takao; Hayato, Asami; Iwakiri, Wataru; Takeuchi, Yoko; Kubota, Megu; Nishida, Kazuki; Enoto, Teruaki; Tamagawa, Toru

2018-02-01

We have developed a gaseous Time Projection Chamber (TPC) containing a single-layered foil of a gas electron multiplier (GEM) to open up a new window on cosmic X-ray polarimetry in the 2-10 keV band. The micro-pattern TPC polarimeter in combination with the Scalable Readout System produced by the RD51 collaboration has been built as an engineering model to optimize detector parameters and improve polarimeter sensitivity. The polarimeter was characterized with unpolarized X-rays from an X-ray generator in a laboratory and polarized X-rays on the BL32B2 beamline at the SPring-8 synchrotron radiation facility. Preliminary results show that the polarimeter has a comparable modulation factor to a prototype of the flight one.

Brightness measurement of an electron impact gas ion source for proton beam writing applications

DOE Office of Scientific and Technical Information (OSTI.GOV)

Liu, N.; Santhana Raman, P.; Department of Electrical and Computer Engineering, National University of Singapore, Singapore 117583

We are developing a high brightness nano-aperture electron impact gas ion source, which can create ion beams from a miniature ionization chamber with relatively small virtual source sizes, typically around 100 nm. A prototype source of this kind was designed and successively micro-fabricated using integrated circuit technology. Experiments to measure source brightness were performed inside a field emission scanning electron microscope. The total output current was measured to be between 200 and 300 pA. The highest estimated reduced brightness was found to be comparable to the injecting focused electron beam reduced brightness. This translates into an ion reduced brightness thatmore » is significantly better than that of conventional radio frequency ion sources, currently used in single-ended MeV accelerators.« less

Brightness measurement of an electron impact gas ion source for proton beam writing applications.

PubMed

Liu, N; Xu, X; Pang, R; Raman, P Santhana; Khursheed, A; van Kan, J A

2016-02-01

We are developing a high brightness nano-aperture electron impact gas ion source, which can create ion beams from a miniature ionization chamber with relatively small virtual source sizes, typically around 100 nm. A prototype source of this kind was designed and successively micro-fabricated using integrated circuit technology. Experiments to measure source brightness were performed inside a field emission scanning electron microscope. The total output current was measured to be between 200 and 300 pA. The highest estimated reduced brightness was found to be comparable to the injecting focused electron beam reduced brightness. This translates into an ion reduced brightness that is significantly better than that of conventional radio frequency ion sources, currently used in single-ended MeV accelerators.

A Study on the Rural Residence in the Northern Area of Zhejiang Province from the Perspective of Green Living Environment

NASA Astrophysics Data System (ADS)

Wang, J.; Gao, W. J.; Wang, C.

2018-05-01

At present, owing to the rapid development of rural construction, it lacks corresponding theories and practices and damages to the features of rural area, ignoring the geography, suitability and green living environment factors. The research selects rural residence as the object, defining “courtyard” as the basic unit for rural residence. It utilizes the principle of topology as the expanding media, by the method of principle of cellular structure and green living environment design strategy. The essay establishes the design and construction system of “rural basic unit”, combining functions and structures, prototype menu, chamber space and compound interface, from the perspective of green living environment. It aims to guide rural construction and protect the ruralliving environment.

DarkSide search for dark matter

NASA Astrophysics Data System (ADS)

Alexander, T.; Alton, D.; Arisaka, K.; Back, H. O.; Beltrame, P.; Benziger, J.; Bonfini, G.; Brigatti, A.; Brodsky, J.; Bussino, S.; Cadonati, L.; Calaprice, F.; Candela, A.; Cao, H.; Cavalcante, P.; Chepurnov, A.; Chidzik, S.; Cocco, A. G.; Condon, C.; D'Angelo, D.; Davini, S.; De Vincenzi, M.; De Haas, E.; Derbin, A.; Di Pietro, G.; Dratchnev, I.; Durben, D.; Empl, A.; Etenko, A.; Fan, A.; Fiorillo, G.; Franco, D.; Fomenko, K.; Forster, G.; Gabriele, F.; Galbiati, C.; Gazzana, S.; Ghiano, C.; Goretti, A.; Grandi, L.; Gromov, M.; Guan, M.; Guo, C.; Guray, G.; Hungerford, E. V.; Ianni, Al; Ianni, An; Joliet, C.; Kayunov, A.; Keeter, K.; Kendziora, C.; Kidner, S.; Klemmer, R.; Kobychev, V.; Koh, G.; Komor, M.; Korablev, D.; Korga, G.; Li, P.; Loer, B.; Lombardi, P.; Love, C.; Ludhova, L.; Luitz, S.; Lukyanchenko, L.; Lund, A.; Lung, K.; Ma, Y.; Machulin, I.; Mari, S.; Maricic, J.; Martoff, C. J.; Meregaglia, A.; Meroni, E.; Meyers, P.; Mohayai, T.; Montanari, D.; Montuschi, M.; Monzani, M. E.; Mosteiro, P.; Mount, B.; Muratova, V.; Nelson, A.; Nemtzow, A.; Nurakhov, N.; Orsini, M.; Ortica, F.; Pallavicini, M.; Pantic, E.; Parmeggiano, S.; Parsells, R.; Pelliccia, N.; Perasso, L.; Perasso, S.; Perfetto, F.; Pinsky, L.; Pocar, A.; Pordes, S.; Randle, K.; Ranucci, G.; Razeto, A.; Romani, A.; Rossi, B.; Rossi, N.; Rountree, S. D.; Saggese, P.; Saldanha, R.; Salvo, C.; Sands, W.; Seigar, M.; Semenov, D.; Shields, E.; Skorokhvatov, M.; Smirnov, O.; Sotnikov, A.; Sukhotin, S.; Suvarov, Y.; Tartaglia, R.; Tatarowicz, J.; Testera, G.; Thompson, J.; Tonazzo, A.; Unzhakov, E.; Vogelaar, R. B.; Wang, H.; Westerdale, S.; Wojcik, M.; Wright, A.; Xu, J.; Yang, C.; Zavatarelli, S.; Zehfus, M.; Zhong, W.; Zuzel, G.

2013-11-01

The DarkSide staged program utilizes a two-phase time projection chamber (TPC) with liquid argon as the target material for the scattering of dark matter particles. Efficient background reduction is achieved using low radioactivity underground argon as well as several experimental handles such as pulse shape, ratio of ionization over scintillation signal, 3D event reconstruction, and active neutron and muon vetos. The DarkSide-10 prototype detector has proven high scintillation light yield, which is a particularly important parameter as it sets the energy threshold for the pulse shape discrimination technique. The DarkSide-50 detector system, currently in commissioning phase at the Gran Sasso Underground Laboratory, will reach a sensitivity to dark matter spin-independent scattering cross section of 10-45 cm2 within 3 years of operation.

Fabricating microfluidic valve master molds in SU-8 photoresist

NASA Astrophysics Data System (ADS)

Dy, Aaron J.; Cosmanescu, Alin; Sluka, James; Glazier, James A.; Stupack, Dwayne; Amarie, Dragos

2014-05-01

Multilayer soft lithography has become a powerful tool in analytical chemistry, biochemistry, material and life sciences, and medical research. Complex fluidic micro-circuits require reliable components that integrate easily into microchips. We introduce two novel approaches to master mold fabrication for constructing in-line micro-valves using SU-8. Our fabrication techniques enable robust and versatile integration of many lab-on-a-chip functions including filters, mixers, pumps, stream focusing and cell-culture chambers, with in-line valves. SU-8 created more robust valve master molds than the conventional positive photoresists used in multilayer soft lithography, but maintained the advantages of biocompatibility and rapid prototyping. As an example, we used valve master molds made of SU-8 to fabricate PDMS chips capable of precisely controlling beads or cells in solution.

Testing of fuel/oxidizer-rich, high-pressure preburners

NASA Technical Reports Server (NTRS)

Lawver, B. R.

1982-01-01

Results of an evaluation of high pressure combustion of fuel rich and oxidizer rich LOX/RP-1 propellants using 4.0 inch diameter prototype preburner injectors and chambers are presented. Testing covered a pressure range from 8.9 to 17.5 MN/square meters (1292 to 2540 psia). Fuel rich mixture ratios ranged from 0.238 to 0.367; oxidizer rich mixture ratios ranged from 27.2 to 47.5. Performance, gas temperature uniformity, and stability data for two fuel rich and two ozidizer rich preburner injectors are presented for a conventional like-on-like (LOL) design and a platelet design injector. Kinetically limited combustion is shown by the excellent agreement of measured fuel rich gas composition and C performance data with kinetic model predictions. The oxidizer rich test results support previous equilibrium combustion predictions.

KSC-2012-4242

NASA Image and Video Library

2012-08-03

CAPE CANAVERAL, Fla. – Inside the Space Life Sciences Laboratory, or SLSL, at NASA’s Kennedy Space Center in Florida, red leaf lettuce plants were harvested from a plant growth chamber. The plants were grown under red and blue LED lights. The plant experiment at Kennedy is part of the Advanced Exploration Systems, or AES, program in NASA’s Human Exploration and Operations Mission Directorate. This plant experiment studies the effects of different types of lighting on plants such as radishes and leaf lettuce. Results of these studies will help provide information on how to grow food sources for deep space exploration missions. AES projects pioneer new approaches for rapidly developing prototype systems, demonstrating key capabilities and validating operational concepts for future human missions beyond Earth orbit. Photo credit: NASA/Frank Ochoa-Gonzales

Effects of a modified through-mask drinking system (MDS) on fluid intake during exercise in chemical protective gear. Report for January-May 1989

DOE Office of Scientific and Technical Information (OSTI.GOV)

Szlyk, P.C.; Sils, I.V.; Tharion, W.J.

This study was designed to evaluate the effects of a modified through-mask drinking system (MDS) on voluntary fluid consumption. Eighteen male volunteers walked on a treadmill (4.02 km/hr, 0 deg. grade, 50 min/hr for 6 hr) in a climatic chamber (dry bulb=32.6 deg C, wet bulb=17.5 deg C, 20.4% relative humidity, and windspeed=8.05 km/hr, producing a WBGT of 22.1 deg C). Subjects wore chemical protective gear (trousers, jacket, boots, gloves, and M17A1 protective mask) and were randomly assigned one of two through-mask and were randomly assigned one of two through-mask drinking systems: CS (n=9), the current gravity fed system ormore » MDS (n=9), a prototype hand-pump drinking system. Because decontamination of the mask and drinking connections was performed prior to drinking, the overall use of the CS was rated significantly more difficult during both work and rest than the MDS. Failure to decontaminate connections prior to drinking was noted early in the trial in 2 soldiers using the CS suggesting an increase risk of accidental contamination associated with this system. Drinking with the MDS had no measurable adverse effect on hydration status of the test subjects: water intake rate, 0.36 L/hr (CS) and 0.42 L/hr (MDS); sweat rate, 0.63 L/hr (CS) and 0.67 L/hr (MDS); body weight loss, 0.32 %/hr (CS) and 0.31 %/hr (MDS).« less

Characterisation of a neutron diffraction detector prototype based on the Trench-MWPC technology

NASA Astrophysics Data System (ADS)

Buffet, J. C.; Clergeau, J. F.; Cuccaro, S.; Guérard, B.; Mandaroux, N.; Marchal, J.; Pentenero, J.; Platz, M.; Van Esch, P.

2017-12-01

The Trench Multi-Wire-Proportional-Chamber is a new type of MWPC which has been designed to fulfill the requirements of the 2D curved neutron detector under development for the XtremeD neutron diffractometer, under construction at ILL. In this design, anode wires are mounted orthogonally to a stack of metallic cathode plates which are insulated from each other by ceramic spacers. A row of teeth is spark-eroded along the edge of the cathode plates so that anode wires appear to be stretched along trenches machined across a segmented cathode plane. This design was tested on a prototype detector module mounted in a vessel filled with a mixture of 3He-Ar-CO2 at 7 bar. The detector configuration as well as measurements performed on this prototype at ILL neutron test beam line are presented. Results show that the Trench-MWPC design provides uniform amplification gain across the detection area despite the absence of the top cathode wires used to balance the electric field in standard Cathode-Anode-Cathode MWPC configurations. The presence of cathode trench side-walls surrounding anode wires minimises the spread of neutron-induced charge across electrodes, allowing for detector operation at reduced amplification gain without compromising the signal to noise per electrode. Pulse-height spectra acquired under various neutron flux conditions demonstrated that the Trench-MWPC design minimises space-charge effects, thanks to its low amplification gain combined with the fast collection of ions by cathode trench side-walls surrounding anode wires. Measurements also showed that this space-charge effect reduction results in a high local count-rate of ~100 kHz at 10% count loss when irradiating the detector with a small 5 mm × 5 mm neutron beam.

The Automated Dynamic Directed Evolution Chamber: A Tool for Studying Extremophile-Environment Interactions in Real Time

NASA Astrophysics Data System (ADS)

Wong, N.; Grace, J. M.; Liang, J.; Owyang, S.; Storrs, A.; Zhou, J.; Rothschild, L. J.; Gentry, D.

2014-12-01

Life acclimated to harsh conditions is frequently difficult to study using normal lab techniques and conventional equipment. Simplified studies using in-lab 'simulated' extreme environments, such as UV bulbs or cold blocks, are manually intensive, error-prone, and lose many complexities of the microbe/environment interaction. We have built a prototype instrument to address this dilemma by allowing automated iterations of microbial cultures to be subject to combinations of modular environmental pressures such as heat, radiation, and chemical exposure. The presence of multiple sensors allows the state of the culture and internal environment to be continuously monitored and adjusted in response.Our first prototype showed successful iterations of microbial growth and thermal exposure. Our second prototype, presented here, performs an demonstration of repeated exposure of Escherichia coli to ultraviolet radiation, a well-established procedure. As the E. coli becomes more resistant to ultraviolet radiation, the device detects their increased survival and growth and increases the dosage accordingly. Calibration data for the instrument was generated by performing the same proof-of-concept exposure experiment, at a smaller scale, by hand. Current performance data indicates that our finalized instrument will have the ability to run hundreds of iterations with multiple selection pressures. The automated sensing and adaptive exposure that the device provides will inform the challenges of managing and culturing life tailored to uncommon environmental stresses. We have designed this device to be flexible, extensible, low-cost and easy to reproduce. We hope that it enter wide use as a tool for conducting scalable studies of the interaction between extremophiles and multiple environmental stresses, and potentially for generating artificial extremophiles as analogues for life we might find in extreme environments here on Earth or elsewhere.