Sample records for changing flow rate

  1. Impacts of changing hydrology on permanent gully growth: experimental results

    NASA Astrophysics Data System (ADS)

    Day, Stephanie S.; Gran, Karen B.; Paola, Chris

    2018-06-01

    Permanent gullies grow through head cut propagation in response to overland flow coupled with incision and widening in the channel bottom leading to hillslope failures. Altered hydrology can impact the rate at which permanent gullies grow by changing head cut propagation, channel incision, and channel widening rates. Using a set of small physical experiments, we tested how changing overland flow rates and flow volumes alter the total volume of erosion and resulting gully morphology. Permanent gullies were modeled as both detachment-limited and transport-limited systems, using two different substrates with varying cohesion. In both cases, the erosion rate varied linearly with water discharge, such that the volume of sediment eroded was a function not of flow rate, but of total water volume. This implies that efforts to reduce peak flow rates alone without addressing flow volumes entering gully systems may not reduce erosion. The documented response in these experiments is not typical when compared to larger preexisting channels where higher flow rates result in greater erosion through nonlinear relationships between water discharge and sediment discharge. Permanent gullies do not respond like preexisting channels because channel slope remains a free parameter and can adjust relatively quickly in response to changing flows.

  2. Effect of flow rate on environmental variables and phytoplankton dynamics: results from field enclosures

    NASA Astrophysics Data System (ADS)

    Zhang, Haiping; Chen, Ruihong; Li, Feipeng; Chen, Ling

    2015-03-01

    To investigate the effects of flow rate on phytoplankton dynamics and related environment variables, a set of enclosure experiments with different flow rates were conducted in an artificial lake. We monitored nutrients, temperature, dissolved oxygen, pH, conductivity, turbidity, chlorophyll- a and phytoplankton levels. The lower biomass in all flowing enclosures showed that flow rate significantly inhibited the growth of phytoplankton. A critical flow rate occurred near 0.06 m/s, which was the lowest relative inhibitory rate. Changes in flow conditions affected algal competition for light, resulting in a dramatic shift in phytoplankton composition, from blue-green algae in still waters to green algae in flowing conditions. These findings indicate that critical flow rate can be useful in developing methods to reduce algal bloom occurrence. However, flow rate significantly enhanced the inter-relationships among environmental variables, in particular by inducing higher water turbidity and vegetative reproduction of periphyton ( Spirogyra). These changes were accompanied by a decrease in underwater light intensity, which consequently inhibited the photosynthetic intensity of phytoplankton. These results warn that a universal critical flow rate might not exist, because the effect of flow rate on phytoplankton is interlinked with many other environmental variables.

  3. Body position and activity, but not heart rate, affect pump flows in patients with continuous-flow left ventricular assist devices.

    PubMed

    Muthiah, Kavitha; Gupta, Sunil; Otton, James; Robson, Desiree; Walker, Robyn; Tay, Andre; Macdonald, Peter; Keogh, Anne; Kotlyar, Eugene; Granger, Emily; Dhital, Kumud; Spratt, Phillip; Jansz, Paul; Hayward, Christopher S

    2014-08-01

    The aim of this study was to determine the contribution of pre-load and heart rate to pump flow in patients implanted with continuous-flow left ventricular assist devices (cfLVADs). Although it is known that cfLVAD pump flow increases with exercise, it is unclear if this increment is driven by increased heart rate, augmented intrinsic ventricular contraction, or enhanced venous return. Two studies were performed in patients implanted with the HeartWare HVAD. In 11 patients, paced heart rate was increased to approximately 40 beats/min above baseline and then down to approximately 30 beats/min below baseline pacing rate (in pacemaker-dependent patients). Ten patients underwent tilt-table testing at 30°, 60°, and 80° passive head-up tilt for 3 min and then for a further 3 min after ankle flexion exercise. This regimen was repeated at 20° passive head-down tilt. Pump parameters, noninvasive hemodynamics, and 2-dimensional echocardiographic measures were recorded. Heart rate alteration by pacing did not affect LVAD flows or LV dimensions. LVAD pump flow decreased from baseline 4.9 ± 0.6 l/min to approximately 4.5 ± 0.5 l/min at each level of head-up tilt (p < 0.0001 analysis of variance). With active ankle flexion, LVAD flow returned to baseline. There was no significant change in flow with a 20° head-down tilt with or without ankle flexion exercise. There were no suction events. Centrifugal cfLVAD flows are not significantly affected by changes in heart rate, but they change significantly with body position and passive filling. Previously demonstrated exercise-induced changes in pump flows may be related to altered loading conditions, rather than changes in heart rate. Copyright © 2014 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.

  4. Functional Changes of Diaphragm Type Shunt Valves Induced by Pressure Pulsation

    NASA Astrophysics Data System (ADS)

    Lee, Chong-Sun; Suh, Chang-Min; Ra, Young-Shin

    Shunt valves used to treat patients with hydrocephalus were tested to investigate influence of pressure pulsation on their flow control characteristics. Our focus was on flow dynamic and functional changes of the small and thin diaphragms in the valves that serve as the main flow control mechanism and are made from silicone elastomer. Firstly, pressure-flow control curves were compared under pulsed and steady flow (without pulsation) conditions. Secondly, functional changes of the valves were tested after a long-term continuous pulsation with a peristaltic pump. Thirdly, flushing procedures selectively conducted by neurosurgeons were simulated with a fingertip pressed on the dome of the valves. As 20cc/hr of flow rate was adjusted at a constant pressure, application of 40mmH2O of pressure pulse increased flow rate through shunt valves more than 60%. As a 90cm length silicone catheter was connected to the valve outlet, increase in the flow rate was substantially reduced to 17.5%. Pressure-flow control characteristics of some valves showed significant changes after twenty-eight days of pressure pulsation at 1.0 Hz under 50.0cc/hr of flow rate. Flushing simulation resulted in temporary decrease in the pressure level. It took three hours to fully recover the normal pressure-flow control characteristics after the flushing. Our results suggest that shunt valves with a thin elastic diaphragm as the main flow control mechanism are sensitive to intracranial pressure pulsation or pressure spikes enough to change their pressure-flow control characteristics.

  5. Improved analysis of transient temperature data from permanent down-hole gauges (PDGs)

    NASA Astrophysics Data System (ADS)

    Zhang, Yiqun; Zheng, Shiyi; Wang, Qi

    2017-08-01

    With the installation of permanent down-hole gauges (PDGs) during oil field development, large volumes of high resolution and continuous down-hole information are obtainable. The interpretation of these real-time temperature and pressure data can optimize well performance, provide information about the reservoir and continuously calibrate the reservoir model. Although the dynamic temperature data have been interpreted in practice to predict flow profiling and provide characteristic information of the reservoir, almost all of the approaches rely on established non-isothermal models which depend on thermodynamic parameters. Another problem comes from the temperature transient analysis (TTA), which is underutilized compared with pressure transient analysis (PTA). In this study, several model-independent methods of TTA were performed. The entire set of PDG data consists of many flow events. By utilizing the wavelet transform, the exact points of flow-rate changes can be located. The flow regime changes, for example, from early time linear flow to later time pseudo-radial flow, among every transient period with constant flow-rate. For the early time region (ETR) that is caused by flow-rate change operations, the TTA, along with the PTA can greatly reduce the uncertainties in flow regime diagnosis. Then, the temperature variations during ETR were examined to infer the true reservoir temperature history, and the relationships between the wavelet detailed coefficients and the flow-rate changes were analysed. For the scenarios with constant reservoir-well parameters, the detailed flow-rate history can be generated by calculating the coefficient of relationship in advance. For later times, the flow regime changes to pseudo-radial flow. An analytical solution was introduced to describe the sand-face temperature. The formation parameters, such as permeability and skin factor, were estimated with the previously calculated flow-rate. It is necessary to analyse temperature variation to overcome data limitation problems when information from other down-hole tools (e.g. expensive but unstable flow meters) is insufficient. This study shows the success in wellbore storage regime diagnosis, flow-rate history reconstruction, and formation parameters estimation using transient temperature data.

  6. The Relationship between High Flow Nasal Cannula Flow Rate and Effort of Breathing in Children.

    PubMed

    Weiler, Thomas; Kamerkar, Asavari; Hotz, Justin; Ross, Patrick A; Newth, Christopher J L; Khemani, Robinder G

    2017-10-01

    To use an objective metric of effort of breathing to determine optimal high flow nasal cannula (HFNC) flow rates in children <3 years of age. Single-center prospective trial in a 24-bed pediatric intensive care unit of children <3 years of age on HFNC. We measured the percent change in pressure∙rate product (PRP) (an objective measure of effort of breathing) as a function of weight-indexed flow rates of 0.5, 1.0, 1.5, and 2.0 L/kg/minute. For a subgroup of patients, 2 different HFNC delivery systems (Fisher & Paykel [Auckland, New Zealand] and Vapotherm [Exeter, New Hampshire]) were compared. Twenty-one patients (49 titration episodes) were studied. The most common diagnoses were bronchiolitis and pneumonia. Overall, there was a significant difference in the percent change in PRP from baseline (of 0.5 L/kg/minute) with increasing flow rates for the entire cohort (P < .001) with largest change at 2.0 L/kg/min (-21%). Subgroup analyses showed no significant difference in percent change in PRP from baseline when comparing the 2 different HFNC delivery systems (P = .12). Patients ≤8 kg experienced a larger percent change in PRP as HFNC flow rates were increased (P = .001) than patients >8 kg. The optimal HFNC flow rate to reduce effort of breathing in infants and young children is approximately 1.5-2.0 L/kg/minute with more benefit seen in children ≤8 kg. Copyright © 2017 Elsevier Inc. All rights reserved.

  7. The dependency of expiratory airway collapse on pump system and flow rate in liquid ventilated rabbits.

    PubMed

    Meinhardt, J P; Ashton, B A; Annich, G M; Quintel, M; Hirschl, R B

    2003-05-30

    To evaluate the influence of pump system and flow pattern on expiratory airway collapse (EAC) in total perfluorocarbon ventilation. - Prospective, controlled, randomized animal trial for determination of (1) post-mortem changes by repeated expiration procedures (EP) with a constant flow piston pump (PP) before and after sacrifice (n = 8 rabbits), (2) differences between pump systems by subjecting animals to both PP and roller pump (RP) circuits for expiration (n = 16 rabbits). EP were performed using a servo-controlled shut-off at airway pressures < 25 cm H subset 2O randomly with either pump at different flows. - Expired volumes before and after sacrifice were not significantly different. PP and RP revealed identical mean flows, while significantly more liquid was drained using PP (p<0.05). Increasing differences towards higher flow rates indicated profound flow pulsatility in RP. - (1) post-mortem changes in expired volumes are not significant, (2) EAC is related to flow rate and pump system; (3) relationship between expiratory flow rate and drainable liquid volume is linear inverse; (4) PP provides higher drainage than RP. - Expiratory airway collapse is related to flow rate and pump system, post mortem changes in expirable volumes are not significant. Relationship between expiratory flow rate and drainable liquid volume is linear inverse, piston pump expiration provides higher drainage volumes than roller pump expiration.

  8. Scram signal generator

    DOEpatents

    Johanson, Edward W.; Simms, Richard

    1981-01-01

    A scram signal generating circuit for nuclear reactor installations monitors a flow signal representing the flow rate of the liquid sodium coolant which is circulated through the reactor, and initiates reactor shutdown for a rapid variation in the flow signal, indicative of fuel motion. The scram signal generating circuit includes a long-term drift compensation circuit which processes the flow signal and generates an output signal representing the flow rate of the coolant. The output signal remains substantially unchanged for small variations in the flow signal, attributable to long term drift in the flow rate, but a rapid change in the flow signal, indicative of a fast flow variation, causes a corresponding change in the output signal. A comparator circuit compares the output signal with a reference signal, representing a given percentage of the steady state flow rate of the coolant, and generates a scram signal to initiate reactor shutdown when the output signal equals the reference signal.

  9. Scram signal generator

    DOEpatents

    Johanson, E.W.; Simms, R.

    A scram signal generating circuit for nuclear reactor installations monitors a flow signal representing the flow rate of the liquid sodium coolant which is circulated through the reactor, and initiates reactor shutdown for a rapid variation in the flow signal, indicative of fuel motion. The scram signal generating circuit includes a long-term drift compensation circuit which processes the flow signal and generates an output signal representing the flow rate of the coolant. The output signal remains substantially unchanged for small variations in the flow signal, attributable to long term drift in the flow rate, but a rapid change in the flow signal, indicative of a fast flow variation, causes a corresponding change in the output signal. A comparator circuit compares the output signal with a reference signal, representing a given percentage of the steady state flow rate of the coolant, and generates a scram signal to initiate reactor shutdown when the output signal equals the reference signal.

  10. An investigation of the basic physics of irrigation in urology and the role of automated pump irrigation in cystoscopy.

    PubMed

    Chang, Dwayne; Manecksha, Rustom P; Syrrakos, Konstantinos; Lawrentschuk, Nathan

    2012-01-01

    To investigate the effects of height, external pressure, and bladder fullness on the flow rate in continuous, non-continuous cystoscopy and the automated irrigation fluid pumping system (AIFPS). Each experiment had two 2-litre 0.9% saline bags connected to a continuous, non-continuous cystoscope or AIFPS via irrigation tubing. Other equipment included height-adjustable drip poles, uroflowmetry devices, and model bladders. In Experiment 1, saline bags were elevated to measure the increment in flow rate. In Experiment 2, saline bags were placed under external pressures to evaluate the effect on flow rate. In Experiment 3, flow rate changes in response to variable bladder fullness were measured. Elevating saline bags caused an increase in flow rates, however the increment slowed down beyond a height of 80 cm. Increase in external pressure on saline bags elevated flow rates, but inconsistently. A fuller bladder led to a decrease in flow rates. In all experiments, the AIFPS posted consistent flow rates. Traditional irrigation systems were susceptible to changes in height of irrigation solution, external pressure application, and bladder fullness thus creating inconsistent flow rates. The AIFPS produced consistent flow rates and was not affected by any of the factors investigated in the study.

  11. Control of Advanced Reactor-Coupled Heat Exchanger System: Incorporation of Reactor Dynamics in System Response to Load Disturbances

    DOE PAGES

    Skavdahl, Isaac; Utgikar, Vivek; Christensen, Richard; ...

    2016-05-24

    We present an alternative control schemes for an Advanced High Temperature Reactor system consisting of a reactor, an intermediate heat exchanger, and a secondary heat exchanger (SHX) in this paper. One scheme is designed to control the cold outlet temperature of the SHX (T co) and the hot outlet temperature of the intermediate heat exchanger (T ho2) by manipulating the hot-side flow rates of the heat exchangers (F h/F h2) responding to the flow rate and temperature disturbances. The flow rate disturbances typically require a larger manipulation of the flow rates than temperature disturbances. An alternate strategy examines the controlmore » of the cold outlet temperature of the SHX (T co) only, since this temperature provides the driving force for energy production in the power conversion unit or the process application. The control can be achieved by three options: (1) flow rate manipulation; (2) reactor power manipulation; or (3) a combination of the two. The first option has a quicker response but requires a large flow rate change. The second option is the slowest but does not involve any change in the flow rates of streams. The final option appears preferable as it has an intermediate response time and requires only a minimal flow rate change.« less

  12. The effect of prolapse repair on urinary flow rates and the relationship to changes in the ultrasound appearance of the bladder neck.

    PubMed

    Duckett, Jonathan; Chakani, Dorothy

    2013-12-01

    To assess whether specific changes in bladder neck morphology, caused by an anterior repair operation, are associated with resolution of overactive bladder and improved urinary flow rates. Sixty-four women with urgency documented on the urgency perception scale (UPS) underwent an anterior repair. Their preoperative flow studies were compared to those 8 weeks postoperatively. Flow rates were compared in those women who reported improved or cured urgency to those who reported no effect. Resolution of urgency was correlated with the change in bladder neck angulation (posterior urethrovesical angle-PUA). 55% (35/64) women reported no urgency after the anterior repair. A further 19% (12/64) were improved and 26% (17/64) were no better. Patients who were cured or improved showed a significant increase in their flow rates after surgery (mean flow=15 before and 17.6 ml/s after) (Mann-Whitney p=0.04). There was a significant change (increase in the PUA angle/straightening of the angle between the bladder and urethra) from a mean value of 123 degrees (SD 49.3) preoperatively to a mean value of 146.8 (SD 29.2) post operatively (p<0.001). Despite an increase in PUA, this was not correlated with an increase in the maximum flow rate centile (p=0.45, r=0.10). An anterior repair results in increased maximum urinary flow rates but this does not correlate to changes in the appearance of the bladder neck. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

  13. Facial skin blood flow responses during exposures to emotionally charged movies.

    PubMed

    Matsukawa, Kanji; Endo, Kana; Ishii, Kei; Ito, Momoka; Liang, Nan

    2018-03-01

    The changes in regional facial skin blood flow and vascular conductance have been assessed for the first time with noninvasive two-dimensional laser speckle flowmetry during audiovisually elicited emotional challenges for 2 min (comedy, landscape, and horror movie) in 12 subjects. Limb skin blood flow and vascular conductance and systemic cardiovascular variables were simultaneously measured. The extents of pleasantness and consciousness for each emotional stimulus were estimated by the subjective rating from -5 (the most unpleasant; the most unconscious) to +5 (the most pleasant; the most conscious). Facial skin blood flow and vascular conductance, especially in the lips, decreased during viewing of comedy and horror movies, whereas they did not change during viewing of a landscape movie. The decreases in facial skin blood flow and vascular conductance were the greatest with the comedy movie. The changes in lip, cheek, and chin skin blood flow negatively correlated (P < 0.05) with the subjective ratings of pleasantness and consciousness. The changes in lip skin vascular conductance negatively correlated (P < 0.05) with the subjective rating of pleasantness, while the changes in infraorbital, subnasal, and chin skin vascular conductance negatively correlated (P < 0.05) with the subjective rating of consciousness. However, none of the changes in limb skin blood flow and vascular conductance and systemic hemodynamics correlated with the subjective ratings. The mental arithmetic task did not alter facial and limb skin blood flows, although the task influenced systemic cardiovascular variables. These findings suggest that the more emotional status becomes pleasant or conscious, the more neurally mediated vasoconstriction may occur in facial skin blood vessels.

  14. Redistribution of blood within the body is important for thermoregulation in an ectothermic vertebrate (Crocodylus porosus).

    PubMed

    Seebacher, Frank; Franklin, Craig E

    2007-11-01

    Changes in blood flow are a principal mechanism of thermoregulation in vertebrates. Changes in heart rate will alter blood flow, although multiple demands for limited cardiac output may compromise effective thermoregulation. We tested the hypothesis that regional differences in blood flow during heating and cooling can occur independently from changes in heart rate. We measured heart rate and blood pressure concurrently with blood flow in the crocodile, Crocodylus porosus. We measured changes in blood flow by laser Doppler flowmetry, and by injecting coloured microspheres. All measurements were made under different heat loads, with and without blocking cholinergic and beta-adrenergic receptors (autonomic blockade). Heart rates were significantly faster during heating than cooling in the control animals, but not when autonomic receptors were blocked. There were no significant differences in blood flow distribution between the control and autonomic blockade treatments. In both treatments, blood flow was directed to the dorsal skin and muscle and away from the tail and duodenum during heating. When the heat source was switched off, there was a redistribution of blood from the dorsal surface to the duodenum. Blood flow to the leg skin and muscle, and to the liver did not change significantly with thermal state. Blood pressure was significantly higher during the autonomic blockade than during the control. Thermal time constants of heating and cooling were unaffected by the blockade of autonomic receptors. We concluded that animals partially compensated for a lack of differential heart rates during heating and cooling by redistributing blood within the body, and by increasing blood pressure to increase flow. Hence, measures of heart rate alone are insufficient to assess physiological thermoregulation in reptiles.

  15. Augmentative effect of pulsatility on the wall shear stress in tube flow.

    PubMed

    Nakata, M; Tatsumi, E; Tsukiya, T; Taenaka, Y; Nishimura, T; Nishinaka, T; Takano, H; Masuzawa, T; Ohba, K

    1999-08-01

    Wall shear stress (WSS) has been considered to play an important role in the physiological and metabolic functions of the vascular endothelial cells. We investigated the effects of the pulse rate and the maximum flow rate on the WSS to clarify the influence of pulsatility. Water was perfused in a 1/2 inch transparent straight cylinder with a nonpulsatile centrifugal pump and a pulsatile pneumatic ventricular assist device (VAD). In nonpulsatile flow (NF), the flow rate was changed 1 to 6 L/min by 1 L/min increments to obtain standard values of WSS at each flow rate. In pulsatile flow (PF), the pulse rate was controlled at 40, 60, and 80 bpm, and the maximum flow rate was varied from 3.3 to 12.0 L/min while the mean flow rate was kept at 3 L/min. The WSS was estimated from the velocity profile at measuring points using the laser illuminated fluorescence method. In NF, the WSS was 12.0 dyne/cm2 at 3 L/min and 33.0 dyne/cm2 at 6 L/min. In PF, the pulse rate change with the same mean, and the maximum flow rate did not affect WSS. On the other hand, the increase in the maximum flow rate at the constant mean flow rate of 3 L/min augmented the mean WSS from 13.1 to 32.9 dyne/cm2. We concluded that the maximum flow rate exerted a substantial augmentative effect on WSS, and the maximum flow rate was a dominant factor of pulsatility in this effect.

  16. A pilot study of change in cerebral activity during personality rating by questionnaire and personal computer.

    PubMed

    Sato, Emi; Matsuda, Kouhei

    2018-06-11

    The purpose of this study was to examine cerebral blood flow in the frontal cortex area during personality self-rating tasks. Our two hypotheses were (1) cerebral blood flow varies based on personality rating condition and (2) cerebral blood flow varies based on the personality traits. This experiment measured cerebral blood flow under 3 personal computer rating conditions and 2 questionnaire conditions. Comparing the rating conditions, the results of the t-test indicated that cerebral blood flow was higher in the questionnaire condition than it was in the personal computer condition. With respect to the Big Five, the result of the correlation coefficient, that is, cerebral blood flow during a personality rating task, changed according to the trait for agreeableness. The results of the analysis of the 5-cluster on individual differences indicated that certain personality traits were related to the factors that increased or decreased cerebral blood flow. An analysis of variance indicated that openness to experience and Behavioural Activation System-drive was significant given that participants with high intellectual curiosity were motivated in this experiment, thus, their cerebral blood flow may have increased. The significance of this experiment was that by employing certain performance measures we could examine differences in physical changes based on personality traits. © 2018 International Union of Psychological Science.

  17. Air Change Rates and Interzonal Flows in Residences, and the Need for Multi-Zone Models for Exposure and Health Analysis

    EPA Science Inventory

    Air change rates (ACRs) and interzonal flows are key determinants of indoor air quality (IAQ) and building energy use. This paper characterizes ACRs and interzonal flows in 126 houses, and evaluates effects of these parameters on IAQ. ACRs measured using weeklong tracer measureme...

  18. Heat transfer in a microvascular network: the effect of heart rate on heating and cooling in reptiles (Pogona barbata and Varanus varius).

    PubMed

    Seebacher, F

    2000-03-21

    Thermally-induced changes in heart rate and blood flow in reptiles are believed to be of selective advantage by allowing animal to exert some control over rates of heating and cooling. This notion has become one of the principal paradigms in reptilian thermal physiology. However, the functional significance of changes in heart rate is unclear, because the effect of heart rate and blood flow on total animal heat transfer is not known. I used heat transfer theory to determine the importance of heat transfer by blood flow relative to conduction. I validated theoretical predictions by comparing them with field data from two species of lizard, bearded dragons (Pogona barbata) and lace monitors (Varanus varius). Heart rates measured in free-ranging lizards in the field were significantly higher during heating than during cooling, and heart rates decreased with body mass. Convective heat transfer by blood flow increased with heart rate. Rates of heat transfer by both blood flow and conduction decreased with mass, but the mass scaling exponents were different. Hence, rate of conductive heat transfer decreased more rapidly with increasing mass than did heat transfer by blood flow, so that the relative importance of blood flow in total animal heat transfer increased with mass. The functional significance of changes in heart rate and, hence, rates of heat transfer, in response to heating and cooling in lizards was quantified. For example, by increasing heart rate when entering a heating environment in the morning, and decreasing heart rate when the environment cools in the evening a Pogona can spend up to 44 min longer per day with body temperature within its preferred range. It was concluded that changes in heart rate in response to heating and cooling confer a selective advantage at least on reptiles of mass similar to that of the study animals (0. 21-5.6 kg). Copyright 2000 Academic Press.

  19. Characteristics of an aerosol photometer while automatically controlling chamber dilution-air flow rate.

    PubMed

    O'Shaughnessy, P T; Hemenway, D R

    2000-10-01

    Trials were conducted to determine those factors that affect the accuracy of a direct-reading aerosol photometer when automatically controlling airflow rate within an exposure chamber to regulate airborne dust concentrations. Photometer response was affected by a shift in the aerosol size distribution caused by changes in chamber flow rate. In addition to a dilution effect, flow rate also determined the relative amount of aerosol lost to sedimentation within the chamber. Additional calculations were added to a computer control algorithm to compensate for these effects when attempting to automatically regulate flow based on a proportional-integral-derivative (PID) feedback control algorithm. A comparison between PID-controlled trials and those performed with a constant generator output rate and dilution-air flow rate demonstrated that there was no significant decrease in photometer accuracy despite the many changes in flow rate produced when using PID control. Likewise, the PID-controlled trials produced chamber aerosol concentrations within 1% of a desired level.

  20. Syringe Pump Performance Maintained with IV Filter Use During Low Flow Rate Delivery for Pediatric Patients.

    PubMed

    Chau, Destiny F; Vasilopoulos, Terrie; Schoepf, Miriam; Zhang, Christina; Fahy, Brenda G

    2016-09-01

    Complex surgical and critically ill pediatric patients rely on syringe infusion pumps for precise delivery of IV medications. Low flow rates and in-line IV filter use may affect drug delivery. To determine the effects of an in-line filter to remove air and/or contaminants on syringe pump performance at low flow rates, we compared the measured rates with the programmed flow rates with and without in-line IV filters. Standardized IV infusion assemblies with and without IV filters (filter and control groups) attached to a 10-mL syringe were primed and then loaded onto a syringe pump and connected to a 16-gauge, 16-cm single-lumen catheter. The catheter was suspended in a normal saline fluid column to simulate the back pressure from central venous circulation. The delivered infusate was measured by gravimetric methods at predetermined time intervals, and flow rate was calculated. Experimental trials for initial programmed rates of 1.0, 0.8, 0.6, and 0.4 mL/h were performed in control and filter groups. For each trial, the flow rate was changed to double the initial flow rate and was then returned to the initial flow rate to analyze pump performance for titration of rates often required during medication administration. These conditions (initial rate, doubling of initial rate, and return to initial rate) were analyzed separately for steady-state flow rate and time to steady state, whereas their average was used for percent deviation analysis. Differences between control and filter groups were assessed using Student t tests with adjustment for multiplicity (using n = 3 replications per group). Mean time from 0 to initial flow (startup delay) was <1 minute in both groups with no statistical difference between groups (P = 1.0). The average time to reach steady-state flow after infusion startup or rate changes was not statistically different between the groups (range, 0.8-5.5 minutes), for any flow rate or part of the trial (initial rate, doubling of initial rate, and return to initial rate), although the study was underpowered to detect small time differences. Overall, the mean steady-state flow rate for each trial was below the programmed flow rate with negative mean percent deviations for each trial. In the 1.0-mL/h initial rate trial, the steady-state flow rate attained was lower in the filter than the control group for the initial rate (P = 0.04) and doubling of initial rate (P = 0.04) with a trend during the return to initial rate (P = 0.06), although this same effect was not observed when doubling the initial rate trials of 0.8 or 0.6 mL/h or any other rate trials compared with the control group. With low flow rates used in complex surgical and pediatric critically ill patients, the addition of IV filters did not confer statistically significant changes in startup delay, flow variability, or time to reach steady-state flow of medications administered by syringe infusion pumps. The overall flow rate was lower than programmed flow rate with or without a filter.

  1. Hydraulic characteristics of the New River in the New River Gorge National River, West Virginia

    USGS Publications Warehouse

    Wiley, J.B.; Appel, David H.

    1989-01-01

    Traveltime, dispersion, water-surface and streambed profiles, and cross-section data were collected for use in application of flow and solute-transport models to the New River in the New River Gorge National River, West Virginia. Dye clouds subjected to increasing and decreasing flow rates (unsteady flow) showed that increasing flows shorten the cloud and decreasing flows lengthen the cloud. After the flow rate was changed and the flow was again steady, traveltime and dispersion characteristics were determined by the new rate of flow. Seven stage/streamflow relations identified the general changes of stream geometry throughout the study reach. Channel cross sections were estimated for model input. Low water and streambed profiles were developed from surveyed water surface elevations and water depths. (USGS)

  2. The vortex as a clock

    NASA Astrophysics Data System (ADS)

    Breidenthal, Robert

    2003-11-01

    Using heuristic arguments, the fundamental effect of acceleration on dissipation in self-similar turbulence is explored. If the ratio of the next vortex rotation period to the last one is always constant, a flow is temporally self-similar. This implies that the vortex rotation period is a linear function of time. For ordinary, unforced turbulence, the period increases linearly in time. However, by imposing an external e-folding time scale on the flow that decreases linearly in time, the dissipation rate is changed from that of the corresponding unforced flow. The dissipation rate depends on the time rate of change of the rotation period as well as the dimensions of the dynamic quantity controlling the flow. For almost all canonical laboratory flows, acceleration reduces the dissipation and entrainment rates. An example is the exponential jet, where the flame length increases by about 20conventional jet. An exception is Rayleigh-Taylor flow, where acceleration increases the dissipation rate.

  3. Effect of Flow Rate Controller on Liquid Steel Flow in Continuous Casting Mold using Numerical Modeling

    NASA Astrophysics Data System (ADS)

    Gursoy, Kadir Ali; Yavuz, Mehmet Metin

    2014-11-01

    In continuous casting operation of steel, the flow through tundish to the mold can be controlled by different flow rate control systems including stopper rod and slide-gate. Ladle changes in continuous casting machines result in liquid steel level changes in tundishes. During this transient event of production, the flow rate controller opening is increased to reduce the pressure drop across the opening which helps to keep the mass flow rate at the desired level for the reduced liquid steel level in tundish. In the present study, computational fluid dynamic (CFD) models are developed to investigate the effect of flow rate controller on mold flow structure, and particularly to understand the effect of flow controller opening on meniscus flow. First, a detailed validation of the CFD models is conducted using available experimental data and the performances of different turbulence models are compared. Then, the constant throughput casting operations for different flow rate controller openings are simulated to quantify the opening effect on meniscus region. The results indicate that the meniscus velocities are significantly affected by the flow rate controller and its opening level. The steady state operations, specified as constant throughput casting, do not provide the same mold flow if the controller opening is altered. Thus, for quality and castability purposes, adjusting the flow controller opening to obtain the fixed mold flow structure is proposed. Supported by Middle East Technical University (METU) BAP (Scientific Research Projects) Coordination.

  4. Bypass valve and coolant flow controls for optimum temperatures in waste heat recovery systems

    DOEpatents

    Meisner, Gregory P

    2013-10-08

    Implementing an optimized waste heat recovery system includes calculating a temperature and a rate of change in temperature of a heat exchanger of a waste heat recovery system, and predicting a temperature and a rate of change in temperature of a material flowing through a channel of the waste heat recovery system. Upon determining the rate of change in the temperature of the material is predicted to be higher than the rate of change in the temperature of the heat exchanger, the optimized waste heat recovery system calculates a valve position and timing for the channel that is configurable for achieving a rate of material flow that is determined to produce and maintain a defined threshold temperature of the heat exchanger, and actuates the valve according to the calculated valve position and calculated timing.

  5. Effects of atmospheric pressure conditions on flow rate of an elastomeric infusion pump.

    PubMed

    Wang, Jong; Moeller, Anna; Ding, Yuanpang Samuel

    2012-04-01

    The effects of pressure conditions, both hyperbaric and hypobaric, on the flow rate of an elastomeric infusion pump were investigated. The altered pressure conditions were tested with the restrictor outlet at two different conditions: (1) at the same pressure condition as the Infusor elastomeric balloon and (2) with the outlet exposed to ambient conditions. Five different pressure conditions were tested. These included ambient pressure (98-101 kilopascals [kPa]) and test pressures controlled to be 10 or 20 kPa below or 75 or 150 kPa above the ambient pressure. A theoretical calculation based on the principles of fluid mechanics was also used to predict the pump's flow rate at various ambient conditions. The conditions in which the Infusor elastomeric pump and restrictor outlet were at the same pressure gave rise to average flow rates within the ±10% tolerance of the calculated target flow rate of 11 mL/hr. The flow rate of the Infusor pump decreased when the pressure conditions changed from hypobaric to ambient. The flow rate increased when the pressure conditions changed from hyperbaric to ambient. The flow rate of the Infusor elastomeric pump was not affected when the balloon reservoir and restrictor outlet were at the same pressure. The flow rate varied from 58.54% to 377.04% of the labeled flow rate when the pressure applied to the reservoir varied from 20 kPa below to 150 kPa above the pressure applied to the restrictor outlet, respectively. The maximum difference between observed flow rates and those calculated by applying fluid mechanics was 4.9%.

  6. Space-based detection of wetlands' surface water level changes from L-band SAR interferometry

    USGS Publications Warehouse

    Wdowinski, S.; Kim, S.-W.; Amelung, F.; Dixon, T.H.; Miralles-Wilhelm, F.; Sonenshein, R.

    2008-01-01

    Interferometric processing of JERS-1 L-band Synthetic Aperture Radar (SAR) data acquired over south Florida during 1993-1996 reveals detectable surface changes in the Everglades wetlands. Although our study is limited to south Florida it has implication for other large-scale wetlands, because south Florida wetlands have diverse vegetation types and both managed and natural flow environments. Our analysis reveals that interferometric coherence level is sensitive to wetland vegetation type and to the interferogram time span. Interferograms with time spans less than six months maintain phase observations for all wetland types, allowing characterization of water level changes in different wetland environments. The most noticeable changes occur between the managed and the natural flow wetlands. In the managed wetlands, fringes are organized, follow patterns related to some of the managed water control structures and have high fringe-rate. In the natural flow areas, fringes are irregular and have a low fringe-rate. The high fringe rate in managed areas reflects dynamic water topography caused by high flow rate due to gate operation. Although this organized fringe pattern is not characteristic of most large-scale wetlands, the high level of water level change enables accurate estimation of the wetland InSAR technique, which lies in the range of 5-10??cm. The irregular and low rate fringe pattern in the natural flow area reflects uninterrupted flow that diffuses water efficiently and evenly. Most of the interferograms in the natural flow area show an elongated fringe located along the transitional zone between salt- and fresh-water wetlands, reflecting water level changes due to ocean tides. ?? 2007 Elsevier Inc. All rights reserved.

  7. Permeability, porosity, and mineral surface area changes in basalt cores induced by reactive transport of CO2-rich brine

    NASA Astrophysics Data System (ADS)

    Luhmann, Andrew J.; Tutolo, Benjamin M.; Bagley, Brian C.; Mildner, David F. R.; Seyfried, William E.; Saar, Martin O.

    2017-03-01

    Four reactive flow-through laboratory experiments (two each at 0.1 mL/min and 0.01 mL/min flow rates) at 150°C and 150 bar (15 MPa) are conducted on intact basalt cores to assess changes in porosity, permeability, and surface area caused by CO2-rich fluid-rock interaction. Permeability decreases slightly during the lower flow rate experiments and increases during the higher flow rate experiments. At the higher flow rate, core permeability increases by more than one order of magnitude in one experiment and less than a factor of two in the other due to differences in preexisting flow path structure. X-ray computed tomography (XRCT) scans of pre- and post-experiment cores identify both mineral dissolution and secondary mineralization, with a net decrease in XRCT porosity of ˜0.7%-0.8% for the larger pores in all four cores. (Ultra) small-angle neutron scattering ((U)SANS) data sets indicate an increase in both (U)SANS porosity and specific surface area (SSA) over the ˜1 nm to 10 µm scale range in post-experiment basalt samples, with differences due to flow rate and reaction time. Net porosity increases from summing porosity changes from XRCT and (U)SANS analyses are consistent with core mass decreases. (U)SANS data suggest an overall preservation of the pore structure with no change in mineral surface roughness from reaction, and the pore structure is unique in comparison to previously published basalt analyses. Together, these data sets illustrate changes in physical parameters that arise due to fluid-basalt interaction in relatively low pH environments with elevated CO2 concentration, with significant implications for flow, transport, and reaction through geologic formations.

  8. Apparatus and method for acoustic monitoring of steam quality and flow

    DOEpatents

    Sinha, Dipen N.; Pantea, Cristian

    2016-09-13

    An apparatus and method for noninvasively monitoring steam quality and flow and in pipes or conduits bearing flowing steam, are described. By measuring the acoustic vibrations generated in steam-carrying conduits by the flowing steam either by direct contact with the pipe or remotely thereto, converting the measured acoustic vibrations into a frequency spectrum characteristic of the natural resonance vibrations of the pipe, and monitoring the amplitude and/or the frequency of one or more chosen resonance frequencies, changes in the steam quality in the pipe are determined. The steam flow rate and the steam quality are inversely related, and changes in the steam flow rate are calculated from changes in the steam quality once suitable calibration curves are obtained.

  9. Influence of Reduced Mass Flow Rate and Chamber Backpressure on Swirl Injector Fluid Mechanics

    NASA Technical Reports Server (NTRS)

    Kenny, R Jeremy; Hulka, James R.

    2008-01-01

    Industry interest in variable-thrust liquid rocket engines places a demand on engine injector technology to operate over a wide range of liquid mass flow rates and chamber backpressures. One injection technology of current interest for variable thrust applications is an injector design with swirled fluids. Current swirl injector design methodologies do not take into account how swirl injector design parameters respond to elevated chamber backpressures at less than design mass flow rates. The current work was created to improve state-of-the-art swirl injector design methods in this area. The specific objective was to study the effects of elevated chamber backpressure and off-design mass flow rates on swirl injector fluid mechanics. Using a backpressure chamber with optical access, water was flowed through a swirl injector at various combinations of chamber backpressure and mass flow rates. The film thickness profile down the swirl injector nozzle section was measured through a transparent nozzle section of the injector. High speed video showed measurable increases in the film thickness profile with application of chamber backpressure and mass flow rates less than design. At prescribed combinations of chamber backpressure and injected mass flow rate, a discrete change in the film thickness profile was observed. Measured injector discharge coefficient values showed different trends with increasing chamber backpressure at low mass flow rates as opposed to near-design mass flow rates. Downstream spray angles showed classic changes in morphology as the mass flow rate was decreased below the design value. Increasing chamber backpressure decreased the spray angle at any injection mass flow rate. Experimental measurements and discussion of these results are reported in this paper.

  10. Effect of hole geometry and Electric-Discharge Machining (EDM) on airflow rates through small diameter holes in turbine blade material

    NASA Technical Reports Server (NTRS)

    Hippensteele, S. A.; Cochran, R. P.

    1980-01-01

    The effects of two design parameters, electrode diameter and hole angle, and two machine parameters, electrode current and current-on time, on air flow rates through small-diameter (0.257 to 0.462 mm) electric-discharge-machined holes were measured. The holes were machined individually in rows of 14 each through 1.6 mm thick IN-100 strips. The data showed linear increase in air flow rate with increases in electrode cross sectional area and current-on time and little change with changes in hole angle and electrode current. The average flow-rate deviation (from the mean flow rate for a given row) decreased linearly with electrode diameter and increased with hole angle. Burn time and finished hole diameter were also measured.

  11. Electrical conduction disturbance effects on dynamic changes of functional mitral regurgitation.

    PubMed

    Fukuda, Shota; Grimm, Richard; Song, Jong-Min; Kihara, Takashi; Daimon, Masao; Agler, Deborah A; Wilkoff, Bruce L; Natale, Andrea; Thomas, James D; Shiota, Takahiro

    2005-12-20

    The aim of this study was to investigate the relationship between dynamics of functional mitral regurgitation (MR) and the degree of electrical conduction disturbance, and to evaluate the impact of cardiac resynchronization therapy (CRT) on MR severity and its phasic pattern. Mechanisms of phasic changes of functional MR, which may be determined by annulus dilation and tethering of the leaflet, remain unclear. Transthoracic two-dimensional echocardiography was performed in 60 patients with functional MR. A biventricular pacemaker was implanted in 19 patients. The mitral annulus area (MAA) and the tenting area (TA) were measured from apical views. The MR volume and fraction were assessed by the quantitative pulsed Doppler method. Instantaneous regurgitation flow rate was measured by proximal flow convergence method. A dynamic change in MR flow rate was evaluated by frame-by-frame analysis throughout systole. A phasic pattern with two peaks at early- and late-systole and decrease in mid-systole was noticed in 57 patients. The early-systolic peak of MR was larger than the late-systolic peak (128.4 +/- 64.3 ml/s vs. 73.9 +/- 55.1 ml/s, p < 0.001). The ratio of flow rate at these two peaks correlated with QRS duration (r = 0.55, p < 0.001). Early-systolic flow rate reduced after CRT (143.9 +/- 60.8 ml/s to 90.7 +/- 54.1 ml/s, p < 0.05), but late-systolic flow rate did not (61.5 +/- 55.0 ml/s to 51.2 +/- 40.9 ml/s, p = NS). A similar pattern was observed for TA, whereas MAA did not change after CRT. Biphasic pattern was found in functional MR, and the ratio of flow rate at two peaks correlated with QRS duration. The CRT decreased regurgitation flow volume by reducing early-systolic MR but not late-systolic MR, resulting in the change in phasic pattern of functional MR.

  12. Interaction of the renin-angiotensin system and the renal nerves in the regulation of rat kidney function.

    PubMed Central

    Handa, R K; Johns, E J

    1985-01-01

    Stimulation of the renal sympathetic nerves in pentobarbitone anaesthetized rats achieved a 13% reduction in renal blood flow, did not change glomerular filtration rate, but reduced urine flow by 37%, absolute sodium excretion by 37%, and fractional sodium excretion by 34%. Following inhibition of converting enzyme with captopril (0.38 mmol kg-1 h-1), similar nerve stimulation reduced both renal blood flow and glomerular filtration rate by 16%, and although urine flow and absolute sodium excretion fell by 32 and 31%, respectively, the 18% fall in fractional sodium excretion was significantly less than that observed in the absence of captopril. Renal nerve stimulation at low levels, which did not change either renal blood flow or glomerular filtration rate, reduced urine flow, and absolute and fractional sodium excretions by 25, 26 and 23%, respectively. In animals receiving captopril at 0.38 mmol kg-1 h-1, low-level nerve stimulation caused small increases in glomerular filtration rate of 7% and urine flow of 12%, but did not change either absolute or fractional sodium excretions. At one-fifth the dose of captopril (0.076 mmol kg-1 h-1), low-level nerve stimulation did not change renal haemodynamics but decreased urine flow, and absolute and fractional sodium excretions by 10, 10 and 8%, respectively. These results showed that angiotensin II production was necessary for regulation of glomerular filtration rate in the face of modest neurally induced reductions in renal blood flow and was compatible with an intra-renal site of action of angiotensin II preferentially at the efferent arteriole. They also demonstrated that in the rat the action of the renal nerves to decrease sodium excretion was dependent on angiotensin II. PMID:3005558

  13. Method of controlling temperature of a thermoelectric generator in an exhaust system

    DOEpatents

    Prior, Gregory P; Reynolds, Michael G; Cowgill, Joshua D

    2013-05-21

    A method of controlling the temperature of a thermoelectric generator (TEG) in an exhaust system of an engine is provided. The method includes determining the temperature of the heated side of the TEG, determining exhaust gas flow rate through the TEG, and determining the exhaust gas temperature through the TEG. A rate of change in temperature of the heated side of the TEG is predicted based on the determined temperature, the determined exhaust gas flow rate, and the determined exhaust gas temperature through the TEG. Using the predicted rate of change of temperature of the heated side, exhaust gas flow rate through the TEG is calculated that will result in a maximum temperature of the heated side of the TEG less than a predetermined critical temperature given the predicted rate of change in temperature of the heated side of the TEG. A corresponding apparatus is provided.

  14. [The value of the thermocouple in the measurement of the gastric mucosal blood-flow. The influence of the occlusion of the celiac artery and prostaglandin E1 on the gastric mucosal blood flow. An experimental study in animals (author's transl)].

    PubMed

    Koch, H; Demling, L

    1976-02-27

    The study has been carried out to ensure the positive evidence of the measurement of the gastric mucosal blood-flow with the aid of the thermocouple (heat-clearance technique). The experiments have shown that the suction pressure of 600 mm mercury column which was used to fix the Thermocouple to the mucosa was indispensable in order to assess the blood-flow in the entire depth of the mucosa. Changes in the mucosal blood-flow are measuured at the same rate in all quadrants of the gastric corpus. The measuring of the blood-flow of a well circumscribed area of the mucosa is therefore representative for the entire corpus. Vasopressin led to a significant reduction of the gastric mucosal blood-flow measured with heat-clearance as well aminopyrine-clearance. There was a linear correlation between the results of both methods. Vasopressin selectively reduces the blood-flow of the gastric mucosa but not of the submucosa, the muscular layer and the serosa. Therefore it seems to be probable that changes in mucosal blood-flow selectively can be measured with the aid of the thermocouple. After previous stimulation with pentagastrin neither mucosal blood-flow nor acid secretion of the stomach were influenced by the occlusion of the celiac artery by 25 %. The occlusion of the celiac artery by 50 % reduced significantly the pentagastrin-stimulated gastric mucosal blood-flow whereas the acid secretion was not influenced. Prostaglandin E1 at a dose rate of 2 mug/kg-h increased significantly arterial and mucosal blood-flow as well as acid secretion of the stomach. In comparison PGE1 administered at a dose rate of 4 mug/kg-h reduced significantly gastric mucosal blood-flow and gastric secretion. PGE1 at a dose rate of 8 mug/kg-h did not produce any significant changes in blood-flow and secretion. The results suggested that the changes of gastric secretion observed with PGE1 were the consequence of primary changes in the gastric mucosal blood-flow.

  15. Deleterious Thermal Effects due to Randomized Flow Paths in Pebble Bed, and Particle Bed Style Reactors

    NASA Technical Reports Server (NTRS)

    Moran, Robert P.

    2013-01-01

    Reactor fuel rod surface area that is perpendicular to coolant flow direction (+S) i.e. perpendicular to the P creates areas of coolant stagnation leading to increased coolant temperatures resulting in localized changes in fluid properties. Changes in coolant fluid properties caused by minor increases in temperature lead to localized reductions in coolant mass flow rates leading to localized thermal instabilities. Reductions in coolant mass flow rates result in further increases in local temperatures exacerbating changes to coolant fluid properties leading to localized thermal runaway. Unchecked localized thermal runaway leads to localized fuel melting. Reactor designs with randomized flow paths are vulnerable to localized thermal instabilities, localized thermal runaway, and localized fuel melting.

  16. Pigtail catheters used for percutaneous fluid drainage: comparison of performance characteristics.

    PubMed

    Macha, Douglas B; Thomas, John; Nelson, Rendon C

    2006-03-01

    To compare the performance characteristics of various single-lumen all-purpose pigtail drainage catheters. The following parameters were compared: flow rates between catheters of the same size, whether changing the fluid viscosity has any effect on catheter comparisons, the effect on flow of leaving an open three-way stopcock in the drainage pathway, the tendency of the catheters to kink, and catheter patency after kinking, as measured according to flow. All-purpose 8.0-, 8.3-, and 8.5-F (collectively referred to as 8-F); 10.0-, 10.2-, and 10.3-F (collectively referred to as 10-F); and 12.0-F pigtail drainage catheters from three manufacturers were evaluated. Data were compared by using two-tailed t tests after normal distributions were confirmed. P < .05 was considered to represent a significant difference. At comparison of the 8-F catheters, the C.R. Bard catheters demonstrated better flow rates than the Cook and Boston Scientific devices. Among the 10-F catheters, there were no significant differences in the flow rates of fluid with viscosity equivalent to that of water between the C.R. Bard and Boston Scientific catheters; however, both these catheter types demonstrated significantly (P < .05) better flow rates than the Cook devices. Among the 12-F catheters, the C.R. Bard catheters demonstrated significantly (P < .05) better flow rates than the other two catheter types. Changing the fluid viscosity caused no changes in comparison results. In all catheter groups, the presence of a stopcock significantly (P < .05) impaired flow. None of the evaluated catheters demonstrated a clear advantage in terms of patency or susceptibility to kinking. At comparison of the in vitro performances of catheters from different manufacturers, the C.R. Bard 8.0-F and Cook 10.2-F catheters had comparable flow rates, and flow rates through the C.R. Bard and Boston Scientific 10.0-F catheters were comparable to flow rates through the Cook and Boston Scientific 12.0-F catheters. Varying viscosity had no effect on comparisons of catheter flow rates; however, a stopcock between the vacuum source and the catheter was noted to impair flow rates in all brands and sizes of evaluated catheters. Copyright RSNA, 2006.

  17. Flow, affect and visual creativity.

    PubMed

    Cseh, Genevieve M; Phillips, Louise H; Pearson, David G

    2015-01-01

    Flow (being in the zone) is purported to have positive consequences in terms of affect and performance; however, there is no empirical evidence about these links in visual creativity. Positive affect often--but inconsistently--facilitates creativity, and both may be linked to experiencing flow. This study aimed to determine relationships between these variables within visual creativity. Participants performed the creative mental synthesis task to simulate the creative process. Affect change (pre- vs. post-task) and flow were measured via questionnaires. The creativity of synthesis drawings was rated objectively and subjectively by judges. Findings empirically demonstrate that flow is related to affect improvement during visual creativity. Affect change was linked to productivity and self-rated creativity, but no other objective or subjective performance measures. Flow was unrelated to all external performance measures but was highly correlated with self-rated creativity; flow may therefore motivate perseverance towards eventual excellence rather than provide direct cognitive enhancement.

  18. Measurement of cerebral blood flow rate and its relationship with brain function using optical coherence tomography

    NASA Astrophysics Data System (ADS)

    Liu, Jian; Wang, Yi; Zhao, Yuqian; Dou, Shidan; Ma, Yushu; Ma, Zhenhe

    2016-03-01

    Activity of brain neurons will lead to changes in local blood flow rate (BFR). Thus, it is important to measure the local BFR of cerebral cortex on research of neuron activity in vivo, such as rehabilitation evaluation after stroke, etc. Currently, laser Doppler flowmetry is commonly used for blood flow measurement, however, relatively low resolution limits its application. Optical coherence tomography (OCT) is a powerful noninvasive 3D imaging modality with high temporal and spatial resolutions. Furthermore, OCT can provide flow distribution image by calculating Doppler frequency shift which makes it possible for blood flow rate measurement. In this paper, we applied OCT to measure the blood flow rate of the primary motor cortex in rats. The animal was immobilized and anesthetized with isoflurane, an incision was made along the sagittal suture, and bone was exposed. A skull window was opened on the primary motor cortex. Then, blood flow rate changes in the primary motor cortex were monitored by our homemade spectral domain OCT with a stimulation of the passive movement of the front legs. Finally, we established the relationship between blood flow rate and the test design. The aim is to demonstrate the potential of OCT in the evaluation of cerebral cortex function.

  19. Permafrost thaw in a nested groundwater-flow system

    USGS Publications Warehouse

    McKenzie, Jeffery M.; Voss, Clifford I.

    2013-01-01

    Groundwater flow in cold regions containing permafrost accelerates climate-warming-driven thaw and changes thaw patterns. Simulation analyses of groundwater flow and heat transport with freeze/thaw in typical cold-regions terrain with nested flow indicate that early thaw rate is particularly enhanced by flow, the time when adverse environmental impacts of climate-warming-induced permafrost loss may be severest. For the slowest climate-warming rate predicted by the Intergovernmental Panel on Climate Change (IPCC), once significant groundwater flow begins, thick permafrost layers can vanish in several hundred years, but survive over 1,000 years where flow is minimal. Large-scale thaw depends mostly on the balance of heat advection and conduction in the supra-permafrost zone. Surface-water bodies underlain by open taliks allow slow sub-permafrost flow, with lesser influence on regional thaw. Advection dominance over conduction depends on permeability and topography. Groundwater flow around permafrost and flow through permafrost impact thaw differently; the latter enhances early thaw rate. Air-temperature seasonality also increases early thaw. Hydrogeologic heterogeneity and topography strongly affect thaw rates/patterns. Permafrost controls the groundwater/surface-water-geomorphology system; hence, prediction and mitigation of impacts of thaw on ecology, chemical exports and infrastructure require improved hydrogeology/permafrost characterization and understanding

  20. Aquia Aquifer Dissolved Cl- and 36Cl/Cl: Implications for Flow Velocities

    NASA Astrophysics Data System (ADS)

    Purdy, Caroline Bascom; Helz, George R.; Mignerey, Alice C.; Kubik, Peter W.; Elmore, David; Sharma, Pankaj; Hemmick, Thomas

    1996-05-01

    The Aquia aquifer (southern Maryland) contains a remarkably smooth Cl- profile (0.46-3.23 ppm) along its flow path. This is interpreted as a record of historic changes in the deposition of Cl- in this region. Those changes have been influenced by the rise and fall of sea level, which has altered the distance of the recharge region from the coastline by ˜200 km. The 36Cl concentration along the flow path is not as smooth as the Cl- profile. Historic variations in cosmogenic production, atmospheric transport, precipitation, and evapotranspiration all might have influenced 36Cl concentrations. A general similarity between the 36Cl and Cl- profiles suggests that changes in precipitation and evapotranspiration rates, which influence both tracers similarly, are particularly important. To reconcile 14C, 36Cl, and hydrologic data, we propose a two-tier model for flow in the Aquia. Shallower portions of the aquifer (<60 m) were subjected to hydraulic gradients and flow rates approximately 5 times larger during the Pleistocene than modern, prepumping rates. At greater depths, flow rates were much slower and less variable; water in this region may be old enough to record some 36Cl decay.

  1. Erosion and deposition on a debris-flow fan

    NASA Astrophysics Data System (ADS)

    Densmore, A. L.; Schuerch, P.; Rosser, N. J.; McArdell, B. W.

    2011-12-01

    The ability of a debris flow to entrain or deposit sediment controls the downstream evolution of flow volume, and ultimately dictates both the geomorphic impact of the flow and the potential hazard that it represents. Our understanding of the patterns of, and controls on, such flow volume changes remains extremely limited, however, partly due to a poor mechanistic grasp of the interactions between debris flows and their bed and banks. In addition, we lack a good understanding of the cumulative long-term effects of sequences of flows in a single catchment-fan system. Here we begin to address these issues by using repeated terrestrial laser scanning (TLS) to characterize the detailed surface change associated with the passage of multiple debris flows on the Illgraben fan, Switzerland. We calculate surface elevation change along a 300 m study reach, and from this derive the downfan rate of flow volume change, or lag rate; for comparison, we also derive the spatially-averaged lag rate over the entire ~2 km length of the fan. Lag rates are broadly comparable over both length scales, indicating that flow behavior does not vary significantly across the fan for most flows, but importantly we find that flow volume at the fan head is a poor predictor of volume at the fan toe. The sign and magnitude of bed elevation change scale with local flow depth; at flow depths < 2 m, erosion and deposition are approximately equally likely, but erosion becomes increasingly dominant for flow depths > 2 m. On the Illgraben fan, this depth corresponds to a basal shear stress of 3-4 kPa. Because flow depth is in part a function of channel cross-sectional topography, which varies strongly both within and between flows, this result indicates that erosion and deposition are likely to be highly dynamic. The dependence of flow volume change on both the channel topography and the flow history may thus complicate efforts to predict debris-flow inundation areas by simple flow routing. We then apply a 2d numerical model of debris-flow fan evolution to explore the key controls on debris-flow routing and topographic development over sequences of multiple flows. We find that fan topographic roughness plays an important role in both channel development and fan surface stability. We also find that, while first-order fan shape is largely insensitive to the input flow sequence, second-order variables such as the pattern of surface exposure ages and the distribution of channel characteristics hold more promise as robust recorders of past flow conditions. Further work is needed to understand the degree to which the TLS-derived (and Illgraben-specific) relationship between bed elevation change and flow depth can be applied in different settings, and to elucidate the role played by coarse debris in controlling patterns of erosion and deposition.

  2. A longitudinal analysis of salivary flow in control subjects and older adults with type 2 diabetes.

    PubMed

    Chávez, E M; Borrell, L N; Taylor, G W; Ship, J A

    2001-02-01

    Many diabetics complain of xerostomia, a condition that can affect oral health, nutritional status, and diet selection. This study's purposes were (1) to investigate the effect on salivary flow of type 2 diabetes and change in glycemic control in a group of older adults over time and (2) to compare flow rates with subjective complaints of xerostomia. A total of 39 older adults, 24 with type 2 diabetes and 15 who were nondiabetic (controls), aged 54-90 years, participated in a 1-year follow-up study. Diabetic status was determined by means of glycosylated hemoglobin (HbA1c) levels and 2-hour glucose tolerance tests. Poor glycemic control was defined as HbA1c > 9%. Unstimulated whole, unstimulated parotid, and stimulated parotid saliva flow rates were measured for all subjects by a single examiner at baseline and 1 year later. Each subject completed a standardized xerostomia questionnaire at every visit. Age, sex, and duration of diabetes did not adversely affect salivary flow rates. Subjects with poorly controlled diabetes had significantly lower stimulated parotid saliva flow rates at both visits. There were no significant changes in flow rates over time on the basis of diabetic status or glycemic control. Subjects with diabetes reported significantly more complaints of thirst but not of xerostomia at 1 year. These results suggest that older adults with poorly controlled diabetes may have impaired salivary flow in comparison with subjects with better controlled diabetes and nondiabetic subjects, yet they may not have concomitant xerostomic complaints. There were no significant changes in salivary flow rates or glycemic control over the 1-year period.

  3. Change regularity of water quality parameters in leakage flow conditions and their relationship with iron release.

    PubMed

    Liu, Jingqing; Shentu, Huabin; Chen, Huanyu; Ye, Ping; Xu, Bing; Zhang, Yifu; Bastani, Hamid; Peng, Hongxi; Chen, Lei; Zhang, Tuqiao

    2017-11-01

    The long-term stagnation in metal water supply pipes, usually caused by intermittent consumption patterns, will cause significant iron release and water quality deterioration, especially at the terminus of pipelines. Another common phenomenon at the terminus of pipelines is leakage, which is considered helpful by allowing seepage of low-quality drinking water resulting from long-term stagnation. In this study, the effect of laminar flow on alleviating water quality deterioration under different leakage conditions was investigated, and the potential thresholds of the flow rate, which can affect the iron release process, were discussed. Based on a galvanized pipe and ductile cast iron pipe pilot platform, which was established at the terminus of pipelines, this research was carried out by setting a series of leakage rate gradients to analyze the influence of different leakage flow rates on iron release, as well as the relationship with chemical and biological parameters. The results showed that the water quality parameters were obviously influenced by the change in flow velocity. Water quality was gradually improved with an increase in flow velocity, but its change regularity reflected a diversity under different flow rates (p < 0.05). The iron release was remarkably correlated to the redox potential, dissolved oxygen, pH, iron-oxidized bacteria and sulfate-reducing bacteria. The cumulative total iron release (r = 0.587, p < 0.05) and total iron release rate (r = 0.71, p < 0.022) were significantly influenced by the changes in flow velocity. In short, they tended first to increase and then to decrease with an increasing flow velocity with the threshold as approximately 40% of the critical laminar flow velocity (1.16 × 10 -3  m/s). For the pipes at the terminus of the drinking water distribution system, when the bulk water was at the critical laminar flow velocity, the concentration of total iron, the quantity and rate of total iron release remain relatively in an ideal and safe situation. Copyright © 2017. Published by Elsevier Ltd.

  4. Effects of Change in Tongue Pressure and Salivary Flow Rate on Swallow Efficiency Following Chemoradiation Treatment for Head and Neck Cancer

    PubMed Central

    Rogus-Pulia, Nicole M.; Larson, Charles; Mittal, Bharat B; Pierce, Marge; Zecker, Steven; Kennelty, Korey; Kind, Amy; Connor, Nadine P.

    2016-01-01

    Purpose Patients treated with chemoradiation for head and neck cancer frequently develop dysphagia. Tissue damage to the oral tongue causing weakness and decreases in saliva production may contribute to dysphagia. Yet, effects of these variables on swallowing-related measures are unclear. The purpose of this study was (1) to determine effects of chemoradiation on tongue pressures, as a surrogate for strength, and salivary flow rates and (2) to elucidate relationships among tongue pressures, saliva production, and swallowing efficiency by bolus type. Methods and Materials 21 patients with head and neck cancer treated with chemoradiation were assessed before and after treatment and matched with 21 healthy control participants who did not receive chemoradiation. Each participant was given a questionnaire to rate dysphagia symptoms. Videofluoroscopic evaluation of swallowing was used to determine swallowing efficiency; the Saxon test measured salivary flow rate; and the Iowa Oral Performance Instrument (IOPI) was used for oral tongue maximum and endurance measures. Results Results revealed significantly lower tongue endurance measures for patients post-treatment as compared to controls (p=.012). Salivary flow rates also were lower compared to pre-treatment (p=.000) and controls (p=.000). Simple linear regression analyses showed that change in salivary flow rate was predictive of change in swallow efficiency measures from pre- to post-treatment for 1mL thin liquid (p=.017), 3mL nectar-thick liquid (p=.026), and 3mL standard barium pudding (p=.011) boluses. Conclusions Based on these findings, it appears that chemoradiation treatment affects tongue endurance and salivary flow rate and these changes may impact swallow efficiency. These factors should be considered when planning treatment for dysphagia. PMID:27492408

  5. Minimum viewing angle for visually guided ground speed control in bumblebees.

    PubMed

    Baird, Emily; Kornfeldt, Torill; Dacke, Marie

    2010-05-01

    To control flight, flying insects extract information from the pattern of visual motion generated during flight, known as optic flow. To regulate their ground speed, insects such as honeybees and Drosophila hold the rate of optic flow in the axial direction (front-to-back) constant. A consequence of this strategy is that its performance varies with the minimum viewing angle (the deviation from the frontal direction of the longitudinal axis of the insect) at which changes in axial optic flow are detected. The greater this angle, the later changes in the rate of optic flow, caused by changes in the density of the environment, will be detected. The aim of the present study is to examine the mechanisms of ground speed control in bumblebees and to identify the extent of the visual range over which optic flow for ground speed control is measured. Bumblebees were trained to fly through an experimental tunnel consisting of parallel vertical walls. Flights were recorded when (1) the distance between the tunnel walls was either 15 or 30 cm, (2) the visual texture on the tunnel walls provided either strong or weak optic flow cues and (3) the distance between the walls changed abruptly halfway along the tunnel's length. The results reveal that bumblebees regulate ground speed using optic flow cues and that changes in the rate of optic flow are detected at a minimum viewing angle of 23-30 deg., with a visual field that extends to approximately 155 deg. By measuring optic flow over a visual field that has a low minimum viewing angle, bumblebees are able to detect and respond to changes in the proximity of the environment well before they are encountered.

  6. Spontaneous and Flow-Driven Interfacial Phase Change: Dynamics of Microemulsion Formation at the Pore Scale.

    PubMed

    Tagavifar, Mohsen; Xu, Ke; Jang, Sung Hyun; Balhoff, Matthew T; Pope, Gary A

    2017-11-14

    The dynamic behavior of microemulsion-forming water-oil-amphiphiles mixtures is investigated in a 2.5D micromodel. The equilibrium phase behavior of such mixtures is well-understood in terms of macroscopic phase transitions. However, what is less understood and where experimental data are lacking is the coupling between the phase change and the bulk flow. Herein, we study the flow of an aqueous surfactant solution-oil mixture in porous media and analyze the dependence of phase formation and spatial phase configurations on the bulk flow rate. We find that a microemulsion forms instantaneously as a boundary layer at the initial surface of contact between the surfactant solution and oil. The boundary layer is temporally continuous because of the imposed convection. In addition to the imposed flow, we observe spontaneous pulsed Marangoni flows that drag the microemulsion and surfactant solution into the oil stream, forming large (macro)emulsion droplets. The formation of the microemulsion phase at the interface distinguishes the situation from that of the more common Marangoni flow with only two phases present. Additionally, an emulsion forms via liquid-liquid nucleation or the Ouzo effect (i.e., spontaneous emulsification) at low flow rates and via mechanical mixing at high flow rates. With regard to multiphase flow, contrary to the common belief that the microemulsion is the wetting liquid, we observe that the minor oil phase wets the solid surface. We show that a layered flow pattern is formed because of the out-of-equilibrium phase behavior at high volumetric flow rates (order of 2 m/day) where advection is much faster than the diffusive interfacial mass transfer and transverse mixing, which promote equilibrium behavior. At lower flow rates (order of 30 cm/day), however, the dynamic and equilibrium phase behaviors are well-correlated. These results clearly show that the phase change influences the macroscale flow behavior.

  7. Microprocessor-Based Valved Controller

    NASA Technical Reports Server (NTRS)

    Norman, Arnold M., Jr.

    1987-01-01

    New controller simpler, more precise, and lighter than predecessors. Mass-flow controller compensates for changing supply pressure and temperature such as occurs when gas-supply tank becomes depleted. By periodically updating calculation of mass-flow rate, controller determines correct new position for valve and keeps mass-flow rate nearly constant.

  8. Reservoir response to thermal and high-pressure well stimulation efforts at Raft River, Idaho

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Plummer, Mitchell; Bradford, Jacob; Moore, Joseph

    An injection stimulation test begun at the Raft River geothermal reservoir in June, 2013 has produced a wealth of data describing well and reservoir response via high-resolution temperature logging and distributed temperature sensing, seismic monitoring, periodic borehole televiewer logging, periodic stepped flow rate tests and tracer injections before and after stimulation efforts. One of the primary measures of response to the stimulation is the relationship between fluid pressure and flow rate, short-term during forced flow rate changes and the long-term change in injectivity. In this paper we examine that hydraulic response using standard pumping test analysis methods, largely because pressuremore » response to the stimulation was not detected, or measurable, in other wells. Analysis of stepped rate flow tests supports the inference from other data that a large fracture, with a radial extent of one to several meters, intersects the well in the target reservoir, suggests that the flow regime is radial to a distance of only several meters and demonstrates that the pressure build-up cone reaches an effective constant head at that distance. The well’s longer term hydraulic response demonstrated continually increasing injectivity but at a dramatically faster rate later from ~2 years out and continuing to the present. The net change in injectivity is significantly greater than observed in other longterm injectivity monitoring studies, with an approximately 150–fold increase occurring over ~2.5 years. While gradually increasing injectivity is a likely consequence of slow migration of a cooling front, and consequent dilation of fractures, the steady, ongoing, rate of increase is contrary to what would be expected in a radial or linear flow regime, where the cooling front would slow with time. As a result, occasional step-like changes in injectivity, immediately following high-flow rate tests suggest that hydro shearing during high-pressure testing altered the near-well permeability structure.« less

  9. Evaluation of the effect of reactant gases mass flow rates on power density in a polymer electrolyte membrane fuel cell

    NASA Astrophysics Data System (ADS)

    Kahveci, E. E.; Taymaz, I.

    2018-03-01

    In this study it was experimentally investigated the effect of mass flow rates of reactant gases which is one of the most important operational parameters of polymer electrolyte membrane (PEM) fuel cell on power density. The channel type is serpentine and single PEM fuel cell has an active area of 25 cm2. Design-Expert 8.0 (trial version) was used with four variables to investigate the effect of variables on the response using. Cell temperature, hydrogen mass flow rate, oxygen mass flow rate and humidification temperature were selected as independent variables. In addition, the power density was used as response to determine the combined effects of these variables. It was kept constant cell and humidification temperatures while changing mass flow rates of reactant gases. From the results an increase occurred in power density with increasing the hydrogen flow rates. But oxygen flow rate does not have a significant effect on power density within determined mass flow rates.

  10. Simulation of the effects of seasonally varying pumping on intraborehole flow and the vulnerability of public-supply wells to contamination

    USGS Publications Warehouse

    Yager, Richard M.; Heywood, Charles E.

    2014-01-01

    Public-supply wells with long screens in alluvial aquifers can produce waters of differing quality from different depths. Seasonal changes in quality are linked to seasonal changes in pumping rates that influence the distribution of flow into the well screens under pumping conditions and the magnitude and direction of intraborehole flow within the wells under ambient conditions. Groundwater flow and transport simulations with MODFLOW and MT3DMS were developed to quantify the effects of changes in average seasonal pumping rates on intraborehole flow and water quality at two long-screened, public-supply wells, in Albuquerque, New Mexico and Modesto, California, where widespread pumping has altered groundwater flow patterns. Simulation results indicate that both wells produce water requiring additional treatment to maintain potable quality in winter when groundwater withdrawals are reduced because less water is derived from parts of the aquifer that contain water requiring less treatment. Simulation results indicate that the water quality at both wells could be improved by increasing average winter-pumping rates to induce more lateral flow from parts of the aquifer that contain better quality water. Arsenic-bearing water produced by the Albuquerque well could be reduced from 55% to 45% by doubling average winter-pumping rate, while nitrate- and uranium-bearing water produced by the Modesto well could be reduced from 95% to 65% by nearly tripling the average winter-pumping rate. Higher average winter-pumping rates would also reduce the volume of intraborehole flow within both wells and prevent the exchange of poor quality water between shallow and deep parts of both aquifers.

  11. Effects of oral health care on salivary flow rate in patients with type 2 diabetes: preliminary study.

    PubMed

    Ibayashi, Haruhisa; Nishiyama, Tomohiro; Tanaka, Masayuki; Pham, Truong-Minh; Yano, Junko; Sakai, Kazuyo; Kobayashi, Atsushi; Yakura, Naonori; Matsuda, Shinya

    2009-07-01

    The purpose of this study is to evaluate the effects of the authors' oral health care program on the stimulated whole salivary flow rate and buffer capacity before and after a 6-month intervention. The authors conducted the intervention study among 25 participants with diabetes. The salivary flow rate and buffer capacity were evaluated before and after this intervention. Overall, the results showed a significant increase in salivary flow rate and no significant change in buffer capacity. Also, it was likely that salivary flow rate significantly increased among patients with more than 20 remaining teeth and patients with well-controlled diabetes. The findings suggest that this program for type 2 diabetes led to an increase in the stimulated whole salivary flow rate.

  12. Noninvasive characterization of a flowing multiphase fluid using ultrasonic interferometry

    DOEpatents

    Sinha, Dipen N.

    2003-11-11

    An apparatus for noninvasively monitoring the flow and/or the composition of a flowing liquid using ultrasound is described. The position of the resonance peaks for a fluid excited by a swept-frequency ultrasonic signal have been found to change frequency both in response to a change in composition and in response to a change in the flow velocity thereof. Additionally, the distance between successive resonance peaks does not change as a function of flow, but rather in response to a change in composition. Thus, a measurement of both parameters (resonance position and resonance spacing), once calibrated, permits the simultaneous determination of flow rate and composition using the apparatus and method of the present invention.

  13. Non-Invasive Characterization Of A Flowing Multi-Phase Fluid Using Ultrasonic Interferometry

    DOEpatents

    Sinha, Dipen N.

    2005-11-01

    An apparatus for noninvasively monitoring the flow and/or the composition of a flowing liquid using ultrasound is described. The position of the resonance peaks for a fluid excited by a swept-frequency ultrasonic signal have been found to change frequency both in response to a change in composition and in response to a change in the flow velocity thereof. Additionally, the distance between successive resonance peaks does not change as a function of flow, but rather in response to a change in composition. Thus, a measurement of both parameters (resonance position and resonance spacing), once calibrated, permits the simultaneous determination of flow rate and composition using the apparatus and method of the present invention.

  14. Noninvasive Characterization Of A Flowing Multiphase Fluid Using Ultrasonic Interferometry

    DOEpatents

    Sinha, Dipen N.

    2005-05-10

    An apparatus for noninvasively monitoring the flow and/or the composition of a flowing liquid using ultrasound is described. The position of the resonance peaks for a fluid excited by a swept-frequency ultrasonic signal have been found to change frequency both in response to a change in composition and in response to a change in the flow velocity thereof. Additionally, the distance between successive resonance peaks does not change as a function of flow, but rather in response to a change in composition. Thus, a measurement of both parameters (resonance position and resonance spacing), once calibrated, permits the simultaneous determination of flow rate and composition using the apparatus and method of the present invention.

  15. Noninvasive characterization of a flowing multiphase fluid using ultrasonic interferometry

    DOEpatents

    Sinha, Dipen N [Los Alamos, NM

    2007-06-12

    An apparatus for noninvasively monitoring the flow and/or the composition of a flowing liquid using ultrasound is described. The position of the resonance peaks for a fluid excited by a swept-frequency ultrasonic signal have been found to change frequency both in response to a change in composition and in response to a change in the flow velocity thereof. Additionally, the distance between successive resonance peaks does not change as a function of flow, but rather in response to a change in composition. Thus, a measurement of both parameters (resonance position and resonance spacing), once calibrated, permits the simultaneous determination of flow rate and composition using the apparatus and method of the present invention.

  16. Combined Effects of Flow Diverting Strategies and Parent Artery Curvature on Aneurysmal Hemodynamics: A CFD Study

    PubMed Central

    Yu, Ying; Lv, Nan; Wang, Shengzhang; Karmonik, Christof; Liu, Jian-Min; Huang, Qinghai

    2015-01-01

    Purpose Flow diverters (FD) are increasingly being considered for treating large or giant wide-neck aneurysms. Clinical outcome is highly variable and depends on the type of aneurysm, the flow diverting device and treatment strategies. The objective of this study was to analyze the effect of different flow diverting strategies together with parent artery curvature variations on altering intra-aneurysmal hemodynamics. Methods Four ideal intracranial aneurysm models with different parent artery curvature were constructed. Computational fluid dynamics (CFD) simulations of the hemodynamics before and after applying five types of flow diverting strategies (single FD, single FD with 5% and 10% packing density of coils, two FDs with 25% and 50% overlapping rate) were performed. Changes in pressure, wall shear stress (WSS), relative residence time (RRT), inflow velocity and inflow volume rate were calculated and compared. Results Each flow diverting strategy resulted in enhancement of RRT and reduction of normalized mean WSS, inflow volume rate and inflow velocity in various levels. Among them, 50% overlapped FD induced most effective hemodynamic changes in RRT and inflow volume rate. The mean pressure only slightly decreased after treatment. Regardless of the kind of implantation of FD, the mean pressure, inflow volume rate and inflow velocity increased and the RRT decreased as the curvature of the parent artery increased. Conclusions Of all flow diverting strategies, overlapping FDs induced most favorable hemodynamic changes. Hemodynamics alterations post treatment were substantially influenced by parent artery curvature. Our results indicate the need of an individualized flow diverting strategy that is tailored for a specific aneurysm. PMID:26398847

  17. Numerical Studies of a Supersonic Fluidic Diverter Actuator for Flow Control

    NASA Technical Reports Server (NTRS)

    Gokoglu, Suleyman A.; Kuczmarski, Maria A.; Culley, Dennis e.; Raghu, Surya

    2010-01-01

    The analysis of the internal flow structure and performance of a specific fluidic diverter actuator, previously studied by time-dependent numerical computations for subsonic flow, is extended to include operation with supersonic actuator exit velocities. The understanding will aid in the development of fluidic diverters with minimum pressure losses and advanced designs of flow control actuators. The self-induced oscillatory behavior of the flow is successfully predicted and the calculated oscillation frequencies with respect to flow rate have excellent agreement with our experimental measurements. The oscillation frequency increases with Mach number, but its dependence on flow rate changes from subsonic to transonic to supersonic regimes. The delay time for the initiation of oscillations depends on the flow rate and the acoustic speed in the gaseous medium for subsonic flow, but is unaffected by the flow rate for supersonic conditions

  18. Growth rate of a penny-shaped crack in hydraulic fracturing of rocks

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Abe, H.; Keer, L.M.; Mura, T.

    1976-01-01

    The deformation and growth of a crack, fractured hydraulically, is investigated when fluid is injected from an inlet into the crack at a constant flow rate. The total flow rate at the inlet is divided as follows: flow rate extracted from an outlet hole; fluid loss rate from the crack surface; and total fluid mass change in the crack. Two cases are considered: (1) inlet flow rate is initially greater than the sum of the outlet flow and fluid loss rates; and (2) the reverse holds true. Ranges are shown for which the crack attains stationary states for given inletmore » flow rate and outlet pressure. For these two cases reasonable outlet flow rates are obtained when the outlet pressure is less than or equal to the difference between the tectonic stress and the fluid head at the inlet. Results are expected to be of use in considerations of heat extraction from hot, dry rock.« less

  19. Field Assessment of A Variable-rate Aerial Application System

    USDA-ARS?s Scientific Manuscript database

    Several experiments were conducted to evaluate the system response of a variable-rate aerial application controller to changing flow rates. The research is collaboration between the USDA, ARS, APTRU and Houma Avionics, USA, manufacturer of a widely used flow controller designed for agricultural airc...

  20. Urine flow is a novel hemodynamic monitoring tool for the detection of hypovolemia.

    PubMed

    Shamir, Micha Y; Kaplan, Leonid; Marans, Rachel S; Willner, Dafna; Klein, Yoram

    2011-03-01

    Noticeable changes in vital signs indicating hypovolemia occur only after 15% of the blood volume is lost. More sensitive variables (e.g., cardiac output, systolic pressure variation and its Δdown component) are invasive and difficult to obtain in the early phase of bleeding. Lately, a new technology for continuous optical measurements of minute-to-minute urine flow rates has become available. We performed a preliminary evaluation to determine whether urine flow can act as an early and sensitive warning of hypovolemia. Eleven patients (ASA physical status I-II) undergoing posterior spine fusion surgery were studied prospectively. Study variables included heart rate, blood pressure (systolic and diastolic), systolic pressure variation and Δdown, minute urinary flow, hemoglobin, blood and urinary sodium, and creatinine in the blood and urine. Urine flow rate was measured using URINFO 2000™ (FlowSense Medical, Misgav, Israel). After recording baseline variables, 10 mL/kg of the patient's blood was shed and a second set of variables was recorded. Subsequently, hypovolemia was reversed by infusing colloid solution (hetastarch 6%) followed by recording a third set of variables. These 3 observations were then compared. An average of 614 ± 143 mL (mean ± SD) of blood was shed. During phlebotomy, the mean urine flow rate decreased from 5.7 ± 8 mL/min to 1.07 ± 2.5 mL/min. Systolic blood pressure and hemoglobin also decreased. Δdown increased. After rehydration, urine flow, blood pressure, and Δdown values returned to baseline. The hemoglobin concentration decreased whereas other variables did not change significantly. Urine flow rate is a dynamic variable that seems to be a reliable indicator of changes in blood volume. These results justify further investigation.

  1. Effects of milk flow on the physiological and behavioural responses to feeding in an infant with hypoplastic left heart syndrome.

    PubMed

    Pados, Britt F; Thoyre, Suzanne M; Estrem, Hayley H; Park, Jinhee; Knafl, George J; Nix, Brant

    2017-01-01

    Infants with hypoplastic left heart syndrome often experience difficulty with oral feeding, which contributes to growth failure, morbidity, and mortality. In response to feeding difficulty, clinicians often change the bottle nipple, and thus milk flow rate. Slow-flow nipples have been found to reduce the stress of feeding in other fragile infants, but no research has evaluated the responses of infants with hypoplastic left heart syndrome to alterations in milk flow. The purpose of this study was to evaluate the physiological and behavioural responses of an infant with hypoplastic left heart syndrome to bottle feeding with either a slow-flow (Dr. Brown's Preemie) or a standard-flow (Dr. Brown's Level 2) nipple. A single infant was studied for three feedings: two slow-flow and one standard-flow. Oral feeding, whether with a slow-flow or a standard-flow nipple, was distressing for this infant. During slow-flow feeding, she experienced more coughing events, whereas during standard-flow she experienced more gagging. Disengagement and compelling disorganisation were most common during feeding 3, that is slow-flow, which occurred 2 days after surgical placement of a gastrostomy tube. Clinically significant changes in heart rate, oxygen saturation, and respiratory rate were seen during all feedings. Heart rate was higher during standard-flow and respiratory rate was higher during slow-flow. Further research is needed to examine the responses of infants with hypoplastic left heart syndrome to oral feeding and to identify strategies that will support these fragile infants as they learn to feed. Future research should evaluate an even slower-flow nipple along with additional supportive feeding strategies.

  2. System analysis of the dynamic response of the coronary circulation to a sudden change in heart rate.

    PubMed

    Dankelman, J; Stassen, H G; Spaan, J A

    1990-03-01

    In this study the response of driving pressure/flow ration on an abrupt change in heart rate was analysed. The difference between the response obtained with constant pressure and constant flow perfusion was also studied. The responses show a fast initial reversed phase followed by a slow phase caused by regulation. To test whether the initial phase could be the result of mechanical changes in the coronary circulation, a model for regulation was extended by the addition of four different mechanical models originating from the literature. These extended models were able to explain the fast initial phase. However, the mechanical model consisting of an intramyocardial compliance (C = 0.08 ml mm Hg-1 100 g-1) with a variable venous resistance, and the model consisting of a waterfall and a small compliance (C = 0.007 ml mm Hg-1 100g-1) both explained these responses best. The analysis showed that there is no direct relationship between rate of change of vascular tone and rate of change of pressure/flow ratio. However, on the basis of the two extended models, it can be predicted that the half-time for the response of regulation to be complete is about 9s with constant pressure perfusion and 15 s with constant flow perfusion.

  3. Automatic tracer-dilution method used for stage-discharge ratings and streamflow hydrographs on small Iowa streams

    USGS Publications Warehouse

    Soenksen, P.J.

    1990-01-01

    Tracer-dilution discharge measurements were made during 14 flow periods at six stations from 1986 through 1988 water years. Ratings were developed at three stations with the aid of these measurements. A loop rating was identified at one station during rapidly-changing flow conditions. Incomplete mixing and dye loss to sediment apparently were problems at some stations. Stage hydrographs were recorded for 38 flows at seven stations. Limited data on background fluorescence during high flows were also obtained.

  4. The effect of changing the contact surface area between pleural liquid and pleura on the turnover of pleural liquid.

    PubMed

    Nakamura, T; Hara, H; Ijima, F; Arai, T; Kira, S

    1984-03-01

    To study the dynamics of pleural liquid, 250 ml of saline labeled with markers were injected into the pleural cavity of anesthetized dogs. For 3 h, liquid volume and concentration of these markers were measured. In a control group of dogs, the turnover rate of pleural liquid was 19.6 +/- 5.6 ml/min and lymphatic flow was 0.58 +/- 0.07 ml/min. In a group of pneumonectomized dogs, the turnover rate and lymphatic flow fell to about one fourth of those in the control group. When the left pulmonary artery was occluded, the turnover rate was halved, but lymphatic flow was not significantly different from that in the control group. These results suggest that the turnover rate of pleural liquid is dependent on the area of contact between pleural liquid and pleura and on the blood flow of the pleura. In addition, it appears that changes in pleural liquid volume are dependent on lymphatic flow.

  5. Influence of Dai-kenchu-to (DKT) on human portal blood flow.

    PubMed

    Ogasawara, Takashi; Morine, Yuji; Ikemoto, Tetsuya; Imura, Satoru; Fujii, Masahiko; Soejima, Yuji; Shimada, Mitsuo

    2008-01-01

    Dai-kenchu-to (DKT) is known as an herbal medicine used for postoperative ileus. However, no report exists about the effect of DKT on portal blood flow. The aim of this study is to clarify the influence of DKT on portal blood flow. To healthy volunteers (Healthy; n = 6), cirrhotic patients (Cirrhosis; n = 7) and liver-transplant patients (LTx; n = 3), DKT (2.5g) with 100mL of warm water was orally administrated in the DKT group, and only warm water was administrated in the control group. The portal blood flow rate (M-VEL: cm/sec.) and portal blood flow (Flow volume: mL/min.) was measured each time after administration using an ultrasonic Doppler method. Furthermore, the arterial blood pressure and heart rate was measured at the same time points. In the DKT group, a significant increase of M-VEL (120%) and flow volume (150%) 30 minutes after administration was observed in both Healthy and Cirrhosis in comparison with the control group. In LTx, there was also a significant increase of flow volume (128%) 30 minutes after administration. However, there was no change in average blood pressure and heart rate in all groups. DKT increases portal blood flow in early phase after oral administration without any significant changes in the blood pressure and heart rate.

  6. Effect of beta-adrenergic blockade with timolol on myocardial blood flow during exercise after myocardial infarction in the dog.

    PubMed

    Herzog, C A; Aeppli, D P; Bache, R J

    1984-12-01

    The effect of beta-adrenergic blockade with timolol (40 micrograms/kg) on myocardial blood flow during rest and graded treadmill exercise was assessed in 12 chronically instrumented dogs 10 to 14 days after myocardial infarction was produced by acute left circumflex coronary artery occlusion. During exercise at comparable external work loads, the heart rate-systolic blood pressure product was significantly decreased after timilol, with concomitant reductions of myocardial blood flow in normal, border and central ischemic areas (p less than 0.001) and increases in subendocardial/subepicardial blood flow ratios (p less than 0.05). In addition to the blunted chronotropic response to exercise, timolol exerted an effect on myocardial blood flow that was not explained by changes in heart rate or blood pressure. At comparable rate-pressure products during exercise, total myocardial blood flow was 24% lower after timolol (p less than 0.02) and flow was redistributed from subepicardium to subendocardium in all myocardial regions. Thus, timolol altered myocardial blood flow during exercise by two separate mechanisms: a negative chronotropic effect, and a significant selective reduction of subepicardial perfusion independent of changes in heart rate or blood pressure with transmural redistribution of flow toward the subendocardium.

  7. Numerical analysis of the effect of side holes of a double J stent on flow rate and pattern.

    PubMed

    Kim, Kyung-Wuk; Choi, Young Ho; Lee, Seung Bae; Baba, Yasutaka; Kim, Hyoung-Ho; Suh, Sang-Ho

    2015-01-01

    A double J stent has been used widely these days for patients with a ureteral stenosis or with renal stones and lithotripsy. The stent has multiple side holes in the shaft, which supply detours for urine flow. Even though medical companies produce various forms of double J stents that have different numbers and positions of side holes in the stent, the function of side holes in fluid dynamics has not been studied well. Here, the flow rate and pattern around the side holes of a double J stent were evaluated in curved models of a stented ureter based on the human anatomy and straight models for comparison. The total flow rate was higher in the stent with a greater number of side holes. The inflow and outflow to the stent through the side holes in the curved ureter was more active than in the straight ureter, which means the flow through side holes exists even in the ureter without ureteral stenosis or occlusion and even in the straight ureter. When the diameter of the ureter changed, the in-stent flow rate in the ureter did not change and the extraluminal flow rate was higher in the ureter with a greater diameter.

  8. Experimental process investigation of a latent heat energy storage system with a staggered heat exchanger with different phase change materials for solar thermal energy storage applications

    NASA Astrophysics Data System (ADS)

    Tsolakoglou, Nikolas P.; Koukou, Maria K.; Vrachopoulos, Michalis Gr.; Tachos, Nikolaos; Lymberis, Kostas; Stathopoulos, Vassilis

    2017-11-01

    This work investigates melting and solidification processes of four different Phase Change Materials (PCM) used as latent heat thermal storage system. The experimental rig was consisted of an insulated tank, filled with the under investigation PCM, a staggered heat exchanger to supply or extract heat from the PCM cavity and a water pump to circulate Heat Transfer Fluid (HTF). Both charging (melting) and discharging (solidification) processes were conducted for two different HTF flow rates. The main scope of this work was to develop a first approach and to investigate the behaviour of PCM under various load conditions (different HTF flow rates). Results show that different HTF flow rates affect melting and solidification time periods; in both processes time was reduced while HTF flow rate was increased but in differentways due to the transition from conduction to convection heat transfer mechanisms.

  9. Elements of an improved model of debris-flow motion

    USGS Publications Warehouse

    Iverson, R.M.

    2009-01-01

    A new depth-averaged model of debris-flow motion describes simultaneous evolution of flow velocity and depth, solid and fluid volume fractions, and pore-fluid pressure. Non-hydrostatic pore-fluid pressure is produced by dilatancy, a state-dependent property that links the depth-averaged shear rate and volumetric strain rate of the granular phase. Pore-pressure changes caused by shearing allow the model to exhibit rate-dependent flow resistance, despite the fact that the basal shear traction involves only rate-independent Coulomb friction. An analytical solution of simplified model equations shows that the onset of downslope motion can be accelerated or retarded by pore-pressure change, contingent on whether dilatancy is positive or negative. A different analytical solution shows that such effects will likely be muted if downslope motion continues long enough, because dilatancy then evolves toward zero, and volume fractions and pore pressure concurrently evolve toward steady states. ?? 2009 American Institute of Physics.

  10. Deposition of TiOxNy Thin Films with Various Nitrogen Flow Rate:. Growth Behavior and Structural Properties

    NASA Astrophysics Data System (ADS)

    Cho, S.-J.; Jung, C.-K.; Bae, I.-S.; Song, Y.-H.; Boo, J.-H.

    2011-06-01

    We have deposited TiOxNy thin films on Si(100) substrates at 500 °C using RF PECVD system. Titanium iso-propoxide was used as precursor with different nitrogen flow rate to control oxygen and nitrogen contents in the films. Changes of chemical states of constituent elements in the deposited films were examined by XPS analysis. The data showed that with increasing nitrogen flow rate, the total amounts of nitrogen and titanium were increased while that of oxygen was decreased, resulting in a binding energy shift toward high energy side. The characteristics of film growth orientation and structure as well as morphology change behavior were also analyzed by XRD, TED, FT-IR, TEM, and SEM. Deposition at higher nitrogen flow rate results in finer clusters with a nanograin size and more effective photocatalytic TiOxNy thin films with hydrophilic surface.

  11. A Comparative study between MPC and PI controller to control vacuum distillation unit for producing LVGO, MVGO, and HVGO

    NASA Astrophysics Data System (ADS)

    Wahid, A.; Prasetyo, A. P.

    2018-03-01

    This study describes the selection of controllers in the vacuum distillation unit (VDU) between a model predictive control (MPC) and a proportional-integral (PI) controller by comparing the integral square error (ISE) values. Design of VDU in this simulation is based on modified Metso Automation Inc. scheme. Controlled variables in this study are feed flow rate, feed temperature, top stage pressure, condenser level, bottom stage temperature, LVGO (light vacuum gas oil), MVGO (medium vacuum gas oil), and HVGO (heavy vacuum gas oil) flow rate. As a result, control performance improvements occurred as using MPC compared to PI controllers, when testing a set-point change, of feed flow rate control, feed temperature, top-stage pressure, bottom-stage temperature and flow rate of LVGO, MVGO, and HVGO, respectively, 36%, 6%, 92%, 53%, 90%, 96% and 88%. Only on condenser level control PI performs much better than the MPC. So PI controller is used for level condenser control. While for the test of disturbance rejection, by changing feed flow rate by 10%, there is improvement of control performance using MPC compared to PI controller on feed temperature control, top-stage pressure, bottom-stage temperature and flow rate LVGO, MVGO and HVGO 0.3%, 0.7%, 14%, 2.7%, 10.6% and 4.3%, respectively.

  12. High quantum yield ZnO quantum dots synthesizing via an ultrasonication microreactor method.

    PubMed

    Yang, Weimin; Yang, Huafang; Ding, Wenhao; Zhang, Bing; Zhang, Le; Wang, Lixi; Yu, Mingxun; Zhang, Qitu

    2016-11-01

    Green emission ZnO quantum dots were synthesized by an ultrasonic microreactor. Ultrasonic radiation brought bubbles through ultrasonic cavitation. These bubbles built microreactor inside the microreactor. The photoluminescence properties of ZnO quantum dots synthesized with different flow rate, ultrasonic power and temperature were discussed. Flow rate, ultrasonic power and temperature would influence the type and quantity of defects in ZnO quantum dots. The sizes of ZnO quantum dots would be controlled by those conditions as well. Flow rate affected the reaction time. With the increasing of flow rate, the sizes of ZnO quantum dots decreased and the quantum yields first increased then decreased. Ultrasonic power changed the ultrasonic cavitation intensity, which affected the reaction energy and the separation of the solution. With the increasing of ultrasonic power, sizes of ZnO quantum dots first decreased then increased, while the quantum yields kept increasing. The effect of ultrasonic temperature on the photoluminescence properties of ZnO quantum dots was influenced by the flow rate. Different flow rate related to opposite changing trend. Moreover, the quantum yields of ZnO QDs synthesized by ultrasonic microreactor could reach 64.7%, which is higher than those synthesized only under ultrasonic radiation or only by microreactor. Copyright © 2016 Elsevier B.V. All rights reserved.

  13. Dynamic change in mitral regurgitant orifice area: comparison of color Doppler echocardiographic and electromagnetic flowmeter-based methods in a chronic animal model.

    PubMed

    Shiota, T; Jones, M; Teien, D E; Yamada, I; Passafini, A; Ge, S; Sahn, D J

    1995-08-01

    The aim of the present study was to investigate dynamic changes in the mitral regurgitant orifice using electromagnetic flow probes and flowmeters and the color Doppler flow convergence method. Methods for determining mitral regurgitant orifice areas have been described using flow convergence imaging with a hemispheric isovelocity surface assumption. However, the shape of flow convergence isovelocity surfaces depends on many factors that change during regurgitation. In seven sheep with surgically created mitral regurgitation, 18 hemodynamic states were studied. The aliasing distances of flow convergence were measured at 10 sequential points using two ranges of aliasing velocities (0.20 to 0.32 and 0.56 to 0.72 m/s), and instantaneous flow rates were calculated using the hemispheric assumption. Instantaneous regurgitant areas were determined from the regurgitant flow rates obtained from both electromagnetic flowmeters and flow convergence divided by the corresponding continuous wave velocities. The regurgitant orifice sizes obtained using the electromagnetic flow method usually increased to maximal size in early to midsystole and then decreased in late systole. Patterns of dynamic changes in orifice area obtained by flow convergence were not the same as those delineated by the electromagnetic flow method. Time-averaged regurgitant orifice areas obtained by flow convergence using lower aliasing velocities overestimated the areas obtained by the electromagnetic flow method ([mean +/- SD] 0.27 +/- 0.14 vs. 0.12 +/- 0.06 cm2, p < 0.001), whereas flow convergence, using higher aliasing velocities, estimated the reference areas more reliably (0.15 +/- 0.06 cm2). The electromagnetic flow method studies uniformly demonstrated dynamic change in mitral regurgitant orifice area and suggested limitations of the flow convergence method.

  14. Investigation of Blade Angle of an Open Cross-Flow Runner

    NASA Astrophysics Data System (ADS)

    Katayama, Yusuke; Iio, Shouichiro; Veerapun, Salisa; Uchiyama, Tomomi

    2015-04-01

    The aim of this study was to develop a nano-hydraulic turbine utilizing drop structure in irrigation channels or industrial waterways. This study was focused on an open-type cross-flow turbine without any attached equipment for cost reduction and easy maintenance. In this study, the authors used an artificial indoor waterfall as lab model. Test runner which is a simple structure of 20 circular arc-shaped blades sandwiched by two circular plates was used The optimum inlet blade angle and the relationship between the power performance and the flow rate approaching theoretically and experimentally were investigated. As a result, the optimum inlet blade angle due to the flow rate was changed. Additionally, allocation rate of power output in 1st stage and 2nd stage is changed by the blade inlet angle.

  15. Dynamic Characteristics of The DSI-Type Constant-Flow Valves

    NASA Astrophysics Data System (ADS)

    Kang, Yuan; Hu, Sheng-Yan; Chou, Hsien-Chin; Lee, Hsing-Han

    Constant flow valves have been presented in industrial applications or academic studies, which compensate recess pressures of a hydrostatic bearing to resist load fluctuating. The flow rate of constant-flow valves can be constant in spite of the pressure changes in recesses, however the design parameters must be specified. This paper analyzes the dynamic responses of DSI-type constant-flow valves that is designed as double pistons on both ends of a spool with single feedback of working pressure and regulating restriction at inlet. In this study the static analysis presents the specific relationships among design parameters for constant flow rate and the dynamic analyses give the variations around the constant flow rate as the working pressure fluctuates.

  16. Enhancement of heat transfer rate on phase change materials with thermocapillary flows

    NASA Astrophysics Data System (ADS)

    Madruga, Santiago; Mendoza, Carolina

    2017-04-01

    We carry out simulations of the melting process on the phase change material n-octadecane in squared geometries in the presence of natural convection and including thermocapillary effects. We show how the introduction of thermocapillary effects enhances the heat transfer rate, being the effect especially relevant for small Bond numbers. Thus induction of Marangoni flows results in a useful mechanism to enhance the typical slow heat transfer rate of paraffin waxes in applications of energy storage or passive control management.

  17. Debris flow-induced topographic changes: effects of recurrent debris flow initiation.

    PubMed

    Chen, Chien-Yuan; Wang, Qun

    2017-08-12

    Chushui Creek in Shengmu Village, Nantou County, Taiwan, was analyzed for recurrent debris flow using numerical modeling and geographic information system (GIS) spatial analysis. The two-dimensional water flood and mudflow simulation program FLO-2D were used to simulate debris flow induced by rainfall during typhoon Herb in 1996 and Mindulle in 2004. Changes in topographic characteristics after the debris flows were simulated for the initiation of hydrological characteristics, magnitude, and affected area. Changes in topographic characteristics included those in elevation, slope, aspect, stream power index (SPI), topographic wetness index (TWI), and hypsometric curve integral (HI), all of which were analyzed using GIS spatial analysis. The results show that the SPI and peak discharge in the basin increased after a recurrence of debris flow. The TWI was higher in 2003 than in 2004 and indicated higher potential of landslide initiation when the slope of the basin was steeper. The HI revealed that the basin was in its mature stage and was shifting toward the old stage. Numerical simulation demonstrated that the parameters' mean depth, maximum depth, affected area, mean flow rate, maximum flow rate, and peak flow discharge were increased after recurrent debris flow, and peak discharge occurred quickly.

  18. Milk Flow Rates from bottle nipples used after hospital discharge.

    PubMed

    Pados, Britt Frisk; Park, Jinhee; Thoyre, Suzanne M; Estrem, Hayley; Nix, W Brant

    To test the milk flow rates and variability in flow rates of bottle nipples used after hospital discharge. Twenty-six nipple types that represented 15 common brands as well as variety in price per nipple and store location sold (e.g., Babies R' Us, Walmart, Dollar Store) were chosen for testing. Ten of each nipple type (n = 260 total) were tested by measuring the amount of infant formula expressed in 1 minute using a breast pump. Mean milk flow rate (mL/min) and coefficient of variation (CV) were calculated. Flow rates of nipples within brand were compared statistically. Milk flow rates varied from 1.68 mL/min for the Avent Natural Newborn Flow to 85.34 mL/min for the Dr. Brown's Standard Y-cut. Variability between nipple types also varied widely, from .03 for the Dr. Brown's Standard Level 3 to .37 for MAM Nipple 1 Slow Flow. The extreme range of milk flow rates found may be significant for medically fragile infants being discharged home who are continuing to develop oral feeding skills. The name of the nipple does not provide clear information about the flow rate to guide parents in decision making. Variability in flow rates within nipples of the same type may complicate oral feeding for the medically fragile infant who may not be able to adapt easily to change in flow rates. Both flow rate and variability should be considered when guiding parents to a nipple choice.

  19. Impact of Climate Change and Human Intervention on River Flow Regimes

    NASA Astrophysics Data System (ADS)

    Singh, Rajendra; Mittal, Neha; Mishra, Ashok

    2017-04-01

    Climate change and human interventions like dam construction bring freshwater ecosystem under stress by changing flow regime. It is important to analyse their impact at a regional scale along with changes in the extremes of temperature and precipitation which further modify the flow regime components such as magnitude, timing, frequency, duration, and rate of change of flow. In this study, the Kangsabati river is chosen to analyse the hydrological alterations in its flow regime caused by dam, climate change and their combined impact using Soil and Water Assessment Tool (SWAT) and the Indicators of Hydrologic Alteration (IHA) program based on the Range of Variability Approach (RVA). Results show that flow variability is significantly reduced due to dam construction with high flows getting absorbed and pre-monsoon low flows being augmented by the reservoir. Climate change alone reduces the high peaks whereas a combination of dam and climate change significantly reduces variability by affecting both high and low flows, thereby further disrupting the functioning of riverine ecosystems. Analysis shows that in the Kangsabati basin, influence of dam is greater than that of the climate change, thereby emphasising the significance of direct human intervention. Keywords: Climate change, human impact, flow regime, Kangsabati river, SWAT, IHA, RVA.

  20. Flow Cell Design for Effective Biosensing

    PubMed Central

    Pike, Douglas J.; Kapur, Nikil; Millner, Paul A.; Stewart, Douglas I.

    2013-01-01

    The efficiency of three different biosensor flow cells is reported. All three flow cells featured a central channel that expands in the vicinity of the sensing element to provide the same diameter active region, but the rate of channel expansion and contraction varied between the designs. For each cell the rate at which the analyte concentration in the sensor chamber responds to a change in the influent analyte concentration was determined numerically using a finite element model and experimentally using a flow-fluorescence technique. Reduced flow cell efficiency with increasing flow rates was observed for all three designs and was related to the increased importance of diffusion relative to advection, with efficiency being limited by the development of regions of recirculating flow (eddies). However, the onset of eddy development occurred at higher flow rates for the design with the most gradual channel expansion, producing a considerably more efficient flow cell across the range of flow rates considered in this study. It is recommended that biosensor flow cells be designed to minimize the tendency towards, and be operated under conditions that prevent the development of flow recirculation. PMID:23344373

  1. PIV measurements in a compact return diffuser under multi-conditions

    NASA Astrophysics Data System (ADS)

    Zhou, L.; Lu, W. G.; Shi, W. D.

    2013-12-01

    Due to the complex three-dimensional geometries of impellers and diffusers, their design is a delicate and difficult task. Slight change could lead to significant changes in hydraulic performance and internal flow structure. Conversely, the grasp of the pump's internal flow pattern could benefit from pump design improvement. The internal flow fields in a compact return diffuser have been investigated experimentally under multi-conditions. A special Particle Image Velocimetry (PIV) test rig is designed, and the two-dimensional PIV measurements are successfully conducted in the diffuser mid-plane to capture the complex flow patterns. The analysis of the obtained results has been focused on the flow structure in diffuser, especially under part-load conditions. The vortex and recirculation flow patterns in diffuser are captured and analysed accordingly. Strong flow separation and back flow appeared at the part-load flow rates. Under the design and over-load conditions, the flow fields in diffuser are uniform, and the flow separation and back flow appear at the part-load flow rates, strong back flow is captured at one diffuser passage under 0.2Qdes.

  2. Computer code for predicting coolant flow and heat transfer in turbomachinery

    NASA Technical Reports Server (NTRS)

    Meitner, Peter L.

    1990-01-01

    A computer code was developed to analyze any turbomachinery coolant flow path geometry that consist of a single flow passage with a unique inlet and exit. Flow can be bled off for tip-cap impingement cooling, and a flow bypass can be specified in which coolant flow is taken off at one point in the flow channel and reintroduced at a point farther downstream in the same channel. The user may either choose the coolant flow rate or let the program determine the flow rate from specified inlet and exit conditions. The computer code integrates the 1-D momentum and energy equations along a defined flow path and calculates the coolant's flow rate, temperature, pressure, and velocity and the heat transfer coefficients along the passage. The equations account for area change, mass addition or subtraction, pumping, friction, and heat transfer.

  3. Granular flow through an aperture: influence of the packing fraction.

    PubMed

    Aguirre, M A; De Schant, R; Géminard, J-C

    2014-07-01

    For the last 50 years, the flow of a granular material through an aperture has been intensely studied in gravity-driven vertical systems (e.g., silos and hoppers). Nevertheless, in many industrial applications, grains are horizontally transported at constant velocity, lying on conveyor belts or floating on the surface of flowing liquids. Unlike fluid flows, that are controlled by the pressure, granular flow is not sensitive to the local pressure but rather to the local velocity of the grains at the outlet. We can also expect the flow rate to depend on the local density of the grains. Indeed, vertical systems are packed in dense configurations by gravity, but, in contrast, in horizontal systems the density can take a large range of values, potentially very small, which may significantly alter the flow rate. In the present article, we study, for different initial packing fractions, the discharge through an orifice of monodisperse grains driven at constant velocity by a horizontal conveyor belt. We report how, during the discharge, the packing fraction is modified by the presence of the outlet, and we analyze how changes in the packing fraction induce variations in the flow rate. We observe that variations of packing fraction do not affect the velocity of the grains at the outlet, and, therefore, we establish that flow-rate variations are directly related to changes in the packing fraction.

  4. Granular flow through an aperture: Influence of the packing fraction

    NASA Astrophysics Data System (ADS)

    Aguirre, M. A.; De Schant, R.; Géminard, J.-C.

    2014-07-01

    For the last 50 years, the flow of a granular material through an aperture has been intensely studied in gravity-driven vertical systems (e.g., silos and hoppers). Nevertheless, in many industrial applications, grains are horizontally transported at constant velocity, lying on conveyor belts or floating on the surface of flowing liquids. Unlike fluid flows, that are controlled by the pressure, granular flow is not sensitive to the local pressure but rather to the local velocity of the grains at the outlet. We can also expect the flow rate to depend on the local density of the grains. Indeed, vertical systems are packed in dense configurations by gravity, but, in contrast, in horizontal systems the density can take a large range of values, potentially very small, which may significantly alter the flow rate. In the present article, we study, for different initial packing fractions, the discharge through an orifice of monodisperse grains driven at constant velocity by a horizontal conveyor belt. We report how, during the discharge, the packing fraction is modified by the presence of the outlet, and we analyze how changes in the packing fraction induce variations in the flow rate. We observe that variations of packing fraction do not affect the velocity of the grains at the outlet, and, therefore, we establish that flow-rate variations are directly related to changes in the packing fraction.

  5. Transition of basaltic lava from pahoehoe to aa, Kilauea Volcano, Hawaii: Field observations and key factors

    USGS Publications Warehouse

    Peterson, Donald W.; Tilling, Robert I.

    1980-01-01

    Nearly all Hawaiian basaltic lava erupts as pahoehoe, and some changes to aa during flowage and cooling; factors governing the transition involve certain critical relations between viscosity and rate of shear strain. If the lava slows, cools, and stops in direct response to concomitant increase in viscosity before these critical relations are reached, it remains pahoehoe. But, if flow mechanics (flow rate, flow dimensions, slope, momentum, etc.) impel the lava to continue to move and deform even after it has become highly viscous, the critical relations may be reached and the lava changes to aa.Typical modes of transition from pahoehoe to aa include: (1) spontaneous formation of relatively stiff clots in parts of the flowing lava where shear rate is highest; these clots grow into discrete, rough, sticky masses to which the remaining fluid lava incrementally adheres; (2) fragmentation and immersion of solid or semi-solid surface crusts of pahoehoe by roiling movements of the flow, forming cores of discrete, tacky masses; (3) sudden renewed movement of lava stored and cooled within surface reservoirs to form clots. The masses, fragments, and clots in these transition modes are characterized by spinose, granulated surfaces; as flow movement continues, the masses and fragments aggregate, fracture, and grind together, completing the transition to aa.Observations show that the critical relation between viscosity and rate of shear strain is inverse: if viscosity is low, a high rate of shear is required to begin the transition to aa; conversely, if viscosity is high, a much lower rate of shear will induce the transition. These relations can be demonstrated qualitatively with simple graphs, which can be used to examine the flow history of any selected finite lava element by tracing the path represented by its changing viscosity and shear rate. A broad, diffuse “transition threshold zone” in these graphs portrays the inverse critical relation between viscosity and shear rate; the transition to aa is represented by the path of the lava element crossing this zone.Moving lava flows can be regarded as natural viscometers, by which shear stress and rate of shear strain at selected points can be determined and viscosity can be computed. By making such determinations under a wide range of conditions on pahoehoe, aa, and transitional flow types, the critical relations that control the pahoehoe-aa transition can be quantified.

  6. Does an Open Recirculation Line Affect the Flow Rate and Pressure in a Neonatal Extracorporeal Life Support Circuit With a Centrifugal or Roller Pump?

    PubMed

    Wang, Shigang; Spencer, Shannon B; Woitas, Karl; Glass, Kristen; Kunselman, Allen R; Ündar, Akif

    2017-01-01

    The objective of this study is to evaluate the impact of an open or closed recirculation line on flow rate, circuit pressure, and hemodynamic energy transmission in simulated neonatal extracorporeal life support (ECLS) systems. The two neonatal ECLS circuits consisted of a Maquet HL20 roller pump (RP group) or a RotaFlow centrifugal pump (CP group), Quadrox-iD Pediatric oxygenator, and Biomedicus arterial and venous cannulae (8 Fr and 10 Fr) primed with lactated Ringer's solution and packed red blood cells (hematocrit 35%). Trials were conducted at flow rates ranging from 200 to 600 mL/min (200 mL/min increments) with a closed or open recirculation line at 36°C. Real-time pressure and flow data were recorded using a custom-based data acquisition system. In the RP group, the preoxygenator flow did not change when the recirculation line was open while the prearterial cannula flow decreased by 15.7-20.0% (P < 0.01). Circuit pressure, total circuit pressure drop, and hemodynamic energy delivered to patients also decreased (P < 0.01). In the CP group, the prearterial cannula flow did not change while preoxygenator flow increased by 13.6-18.8% (P < 0.01). Circuit pressure drop and hemodynamic energy transmission remained the same. The results showed that the shunt of an open recirculation line could decrease perfusion flow in patients in the ECLS circuit using a roller pump, but did not change perfusion flow in the circuit using a centrifugal pump. An additional flow sensor is needed to monitor perfusion flow in patients if any shunts exist in the ECLS circuit. © 2016 International Center for Artificial Organs and Transplantation and Wiley Periodicals, Inc.

  7. 40 CFR 1065.650 - Emission calculations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... from a changing flow rate or a constant flow rate (including discrete-mode steady-state testing), as...·hr e NOx = 64.975/25.783 e NOx = 2.520 g/(kW·hr) (2) For discrete-mode steady-state testing, you may... method not be used if there are any work flow paths described in § 1065.210 that cross the system...

  8. Milk flow rates from bottle nipples used after hospital discharge

    PubMed Central

    Pados, Britt Frisk; Park, Jinhee; Thoyre, Suzanne M.; Estrem, Hayley; Nix, W. Brant

    2016-01-01

    Purpose To test the milk flow rates and variability in flow rates of bottle nipples used after hospital discharge. Study Design and Methods Twenty-six nipple types that represented 15 common brands as well as variety in price per nipple and store location sold (e.g., Babies R’ Us, Walmart, Dollar Store) were chosen for testing. Ten of each nipple type (n=260 total) were tested by measuring the amount of infant formula expressed in one minute using a breast pump. Mean milk flow rate (mL/min) and coefficient of variation (CV) were calculated. Flow rates of nipples within brand were compared statistically. Results Milk flow rates varied from 1.68 mL/min for the Avent Natural Newborn Flow to 85.34 mL/min for the Dr. Brown’s Standard Y-cut. Variability between nipple types also varied widely, from .03 for the Dr. Brown’s Standard Level 3 to .37 for MAM Nipple 1 Slow Flow. Clinical Implications The extreme range of milk flow rates found may be significant for medically fragile infants being discharged home who are continuing to develop oral feeding skills. The name of the nipple does not provide clear information about the flow rate to guide parents in decision-making. Variability in flow rates within nipples of the same type may complicate oral feeding for the medically fragile infant who may not be able to adapt easily to change in flow rates. Both flow rate and variability should be considered when guiding parents to a nipple choice. PMID:27008466

  9. Use of a parallel path nebulizer for capillary-based microseparation techniques coupled with an inductively coupled plasma mass spectrometer for speciation measurements

    NASA Astrophysics Data System (ADS)

    Yanes, Enrique G.; Miller-Ihli, Nancy J.

    2004-06-01

    A low flow, parallel path Mira Mist CE nebulizer designed for capillary electrophoresis (CE) was evaluated as a function of make-up solution flow rate, composition, and concentration, as well as the nebulizer gas flow rate. This research was conducted in support of a project related to the separation and quantification of cobalamin (vitamin B-12) species using microseparation techniques combined with inductively coupled plasma mass spectrometry (ICP-MS) detection. As such, Co signals were monitored during the nebulizer characterization process. Transient effects in the ICP were studied to evaluate the suitability of using gradients for microseparations and the benefit of using methanol for the make-up solution was demonstrated. Co signal response changed significantly as a function of changing methanol concentrations of the make-up solution and maximum signal enhancement was seen at 20% methanol with a 15 μl/min flow rate. Evaluation of the effect of changing the nebulizer gas flow rates showed that argon flows from 0.8 to 1.2 l/min were equally effective. The Mira Mist CE parallel path nebulizer was then evaluated for interfacing capillary microseparation techniques including capillary electrophoresis (CE) and micro high performance liquid chromatography (μHPLC) to inductively coupled plasma mass spectrometry (ICP-MS). A mixture of four cobalamin species standards (cyanocobalamin, hydroxocobalamin, methylcobalamin, and 5' deoxyadenosylcobalamin) and the corrinoid analogue cobinamide dicyanide were successfully separated using both CE-ICP-MS and μHPLC-ICP-MS using the parallel path nebulizer with a make-up solution containing 20% methanol with a flow rate of 15 μl/min.

  10. Fluctuations of wormlike micelle fluids in capillary flow

    NASA Astrophysics Data System (ADS)

    Salipante, Paul; Meek, Stephen; Hudson, Steven; Polymers; Complex Fluids Group Team

    2017-11-01

    We investigate the effect of entrance geometry on the flow stability of wormlike micelles solutions in capillary flow. These solutions exhibit strong shear thinning behavior resulting from micelle breakage and have been observed to undergo large flow rate fluctuations. We investigate these fluctuations using simultaneous measurements of flow rate and pressure drop across a capillary, and we adjust entrance geometry. With a tapered constriction, we observe large persistent fluctuations above a critical flow rate, characterized by rapid decreases in the pressure drop with corresponding increase in flow rate followed by a period of recovery where pressure increases and flow rate decreases. Flow field observations in the tapered entrance show large flow circulations. An abrupt contraction produces smaller transient fluidized jets forming upstream of the constriction and the magnitude of the fluctuations are significantly diminished. The effect of fluid properties is studied by comparing the magnitude and timescales of the fluctuations for surfactant systems with different relaxation times. The onset of fluctuations is compared to a criterion for the onset of elastic instabilities and the magnitude is compared to estimates for changes in channel resistance. NIST on a Chip.

  11. Flowfield analysis for successive oblique shock wave-turbulent boundary layer interactions

    NASA Technical Reports Server (NTRS)

    Sun, C. C.; Childs, M. E.

    1976-01-01

    A computation procedure is described for predicting the flowfields which develop when successive interactions between oblique shock waves and a turbulent boundary layer occur. Such interactions may occur, for example, in engine inlets for supersonic aircraft. Computations are carried out for axisymmetric internal flows at M 3.82 and 2.82. The effect of boundary layer bleed is considered for the M 2.82 flow. A control volume analysis is used to predict changes in the flow field across the interactions. Two bleed flow models have been considered. A turbulent boundary layer program is used to compute changes in the boundary layer between the interactions. The results given are for flows with two shock wave interactions and for bleed at the second interaction site. In principle the method described may be extended to account for additional interactions. The predicted results are compared with measured results and are shown to be in good agreement when the bleed flow rate is low (on the order of 3% of the boundary layer mass flow), or when there is no bleed. As the bleed flow rate is increased, differences between the predicted and measured results become larger. Shortcomings of the bleed flow models at higher bleed flow rates are discussed.

  12. Performance analysis of axial flow pump on gap changing between impeller and guide vane

    NASA Astrophysics Data System (ADS)

    Wang, W. J.; Liang, Q. H.; Wang, Y.; Yang, Y.; Yin, G.; Shi, X. X.

    2013-12-01

    In order to study the influence on gap changing of the static and dynamic components in axial flow pump, the axial flow pump model (TJ04-ZL-06) that used in the eastern of south-to-north water diversion project was selected. Steady turbulence field with different gaps was simulated by standard κ-ε turbulence model and double-time stepping methods. Information on the pressure distribution and velocity distribution of impeller surfaces were obtained. Then, calculated results were compared with the test results and analyzed. The results show that the performance of pump is not sensitive with the axial gap width under design conditions and the large flow rate condition. With increasing gap width, it will be improved in low flow rate condition. The attack angle of impeller inlet in small flow rate condition become small and the flow separation phenomenon can be observed in this condition. The axial velocity distribution of impeller outlet is nonlinear and to increase the axial gap is to improve the flow pattern near the hub effectively. The trend of calculating results is identical with test. It will play a guiding role to the axial pump operation and design in south-to-north water diversion project.

  13. Improving Bedload Transport Predictions by Incorporating Hysteresis

    NASA Astrophysics Data System (ADS)

    Crowe Curran, J.; Gaeuman, D.

    2015-12-01

    The importance of unsteady flow on sediment transport rates has long been recognized. However, the majority of sediment transport models were developed under steady flow conditions that did not account for changing bed morphologies and sediment transport during flood events. More recent research has used laboratory data and field data to quantify the influence of hysteresis on bedload transport and adjust transport models. In this research, these new methods are combined to improve further the accuracy of bedload transport rate quantification and prediction. The first approach defined reference shear stresses for hydrograph rising and falling limbs, and used these values to predict total and fractional transport rates during a hydrograph. From this research, a parameter for improving transport predictions during unsteady flows was developed. The second approach applied a maximum likelihood procedure to fit a bedload rating curve to measurements from a number of different coarse bed rivers. Parameters defining the rating curve were optimized for values that maximized the conditional probability of producing the measured bedload transport rate. Bedload sample magnitude was fit to a gamma distribution, and the probability of collecting N particles in a sampler during a given time step was described with a Poisson probability density function. Both approaches improved estimates of total transport during large flow events when compared to existing methods and transport models. Recognizing and accounting for the changes in transport parameters over time frames on the order of a flood or flood sequence influences the choice of method for parameter calculation in sediment transport calculations. Those methods that more tightly link the changing flow rate and bed mobility have the potential to improve bedload transport rates.

  14. Effect of grain port length-diameter ratio on combustion performance in hybrid rocket motors

    NASA Astrophysics Data System (ADS)

    Cai, Guobiao; Zhang, Yuanjun; Tian, Hui; Wang, Pengfei; Yu, Nanjia

    2016-11-01

    The objectives of this study are to develop a more accurate regression rate considering the oxidizer mass flow and the fuel grain geometry configuration with numerical and experimental investigations in polyethylene (PE)/90% hydrogen peroxide (HP) hybrid rocket. Firstly, a 2-D axisymmetric CFD model with turbulence, chemistry reaction, solid-gas coupling is built to investigate the combustion chamber internal flow structure. Then a more accurate regression formula is proposed and the combustion efficiency changing with the length-diameter ratio is studied. A series experiments are conducted in various oxidizer mass flow to analyze combustion performance including the regression rate and combustion efficiency. The regression rates are measured by the fuel mass reducing and diameter changing. A new regression rate formula considering the fuel grain configuration is proposed in this paper. The combustion efficiency increases with the length-diameter ratio changing. To improve the performance of a hybrid rocket motor, the port length-diameter ratio is suggested 10-12 in the paper.

  15. Micromixer-based time-resolved NMR: applications to ubiquitin protein conformation.

    PubMed

    Kakuta, Masaya; Jayawickrama, Dimuthu A; Wolters, Andrew M; Manz, Andreas; Sweedler, Jonathan V

    2003-02-15

    Time-resolved NMR spectroscopy is used to studychanges in protein conformation based on the elapsed time after a change in the solvent composition of a protein solution. The use of a micromixer and a continuous-flow method is described where the contents of two capillary flows are mixed rapidly, and then the NMR spectra of the combined flow are recorded at precise time points. The distance after mixing the two fluids and flow rates define the solvent-protein interaction time; this method allows the measurement of NMR spectra at precise mixing time points independent of spectral acquisition time. Integration of a micromixer and a microcoil NMR probe enables low-microliter volumes to be used without losing significant sensitivity in the NMR measurement. Ubiquitin, the model compound, changes its conformation from native to A-state at low pH and in 40% or higher methanol/water solvents. Proton NMR resonances of the His-68 and the Tyr-59 of ubiquitin are used to probe the conformational changes. Mixing ubiquitin and methanol solutions under low pH at microliter per minute flow rates yields both native and A-states. As the flow rate decreases, yielding longer reaction times, the population of the A-state increases. The micromixer-NMR system can probe reaction kinetics on a time scale of seconds.

  16. Aerodynamic and Acoustic Effects of Abrupt Frequency Changes in Excised Larynges

    ERIC Educational Resources Information Center

    Alipour, Fariborz; Finnegan, Eileen M.; Scherer, Ronald C.

    2009-01-01

    Purpose: To determine the aerodynamic and acoustic effects due to a sudden change from chest to falsetto register or vice versa. It was hypothesized that the continuous change in subglottal pressure and flow rate alone (pressure-flow sweep [PFS]) can trigger a mode change in the canine larynx. Method: Ten canine larynges were each mounted over a…

  17. Gingival blood flow measurement with a non-contact laser flowmeter.

    PubMed

    Matsuki, M; Xu, Y B; Nagasawa, T

    2001-07-01

    A non-contact laser flowmeter was used to measure the changing of the gingival blood flow. Five university students with healthy oral condition were selected in this study. The blood flow measurement on the extensor digitorum (above the head of third metacarpal), with the changing of distance and angle between the probe and the tissue was used as a pre-study experiment. Blood flow rate was determined in the labial gingiva (2 mm above the cervical line) of upper central incisor using a stent fixing the probe at a 3-mm distance from the tissue. A basal level of gingival blood flow was taken two times each day for 5 days. The effects of water of different temperatures on the gingival blood flow are discussed. With the changing of distance, the blood flow rate became smaller, but there was no significant effect from the angle. The reproducibility was acceptable through the 5-day measurement. After stimulating with warm and body temperature water, the blood flow first increased significantly and then went back to the basal line (faster with the body temperature water). With cold water, different reactions between the subjects were observed.

  18. Potential effects of timber harvest and water management on streamflow dynamics and sediment transport

    Treesearch

    C. A. Troendle; W. K. Olsen

    1994-01-01

    The sustainability of aquatic and riparian ecological systems is strongly tied to the dynamics of the streamflow regime. Timber harvest can influence the flow regime by increasing total flow, altering peak discharge rate, and changing the duration of flows of differing frequency of occurrence. These changes in the energy and sediment transporting capability of the...

  19. Critical phenomenon of granular flow on a conveyor belt.

    PubMed

    De-Song, Bao; Xun-Sheng, Zhang; Guang-Lei, Xu; Zheng-Quan, Pan; Xiao-Wei, Tang; Kun-Quan, Lu

    2003-06-01

    The relationship between the granular wafer movement on a two-dimensional conveyor belt and the size of the exit together with the velocity of the conveyor belt has been studied in the experiment. The result shows that there is a critical speed v(c) for the granular flow when the exit width d is fixed (where d=R/D, D being the diameter of a granular wafers). When vv(c), the flow rate Q is described as Q=Crho(v)(beta)(d-k)(3/2). These are the effects of the interaction among the granular wafers and the change of the states of the granular flow due to the changing of the speed or the exit width d.

  20. Different elution modes and field programming in gravitational field-flow fractionation. III. Field programming by flow-rate gradient generated by a programmable pump.

    PubMed

    Plocková, J; Chmelík, J

    2001-05-25

    Gravitational field-flow fractionation (GFFF) utilizes the Earth's gravitational field as an external force that causes the settlement of particles towards the channel accumulation wall. Hydrodynamic lift forces oppose this action by elevating particles away from the channel accumulation wall. These two counteracting forces enable modulation of the resulting force field acting on particles in GFFF. In this work, force-field programming based on modulating the magnitude of hydrodynamic lift forces was implemented via changes of flow-rate, which was accomplished by a programmable pump. Several flow-rate gradients (step gradients, linear gradients, parabolic, and combined gradients) were tested and evaluated as tools for optimization of the separation of a silica gel particle mixture. The influence of increasing amount of sample injected on the peak resolution under flow-rate gradient conditions was also investigated. This is the first time that flow-rate gradients have been implemented for programming of the resulting force field acting on particles in GFFF.

  1. Optical spectral sweep comb liquid flow rate sensor.

    PubMed

    Shen, Changyu; Lian, Xiaokang; Kavungal, Vishnu; Zhong, Chuan; Liu, Dejun; Semenova, Yuliya; Farrell, Gerald; Albert, Jacques; Donegan, John F

    2018-02-15

    In microfluidic chip applications, the flow rate plays an important role. Here we propose a simple liquid flow rate sensor by using a tilted fiber Bragg grating (TFBG) as the sensing element. As the water flows in the vicinity of the TFBG along the fiber axis direction, the TFBG's spectrum changes due to its contact with water. By comparing the time-swept spectra of the TFBG in water to that of the TFBG with water flowing over it, a spectral sweep comb was formed, and the flow rate can be detected by selecting a suitable sweeping frequency. The proposed sensor has a high Q-value of over 17,000 for the lower rate and a large detectable range from 0.0058 mm/s to 3.2 mm/s. And the calculated corresponding lower detectable flow rate of 0.03 nL/s is 3 orders magnitude better than that of the current fiber flowmeter. Meanwhile, the proposed sensor has the temperature self-compensation function for the variation of the external temperature. We believe that this simple configuration will open a research direction of the TFBG-deriving theory and configuration for lower flow rate measurements for microfluidic chip applications.

  2. A novel compact heat exchanger using gap flow mechanism.

    PubMed

    Liang, J S; Zhang, Y; Wang, D Z; Luo, T P; Ren, T Q

    2015-02-01

    A novel, compact gap-flow heat exchanger (GFHE) using heat-transfer fluid (HTF) was developed in this paper. The detail design of the GFHE coaxial structure which forms the annular gap passage for HTF is presented. Computational fluid dynamics simulations were introduced into the design to determine the impacts of the gap width and the HTF flow rate on the GFHE performance. A comparative study on the GFHE heating rate, with the gap widths ranged from 0.1 to 1.0 mm and the HTF flow rates ranged from 100 to 500 ml/min, was carried out. Results show that a narrower gap passage and a higher HTF flow rate can yield a higher average heating rate in GFHE. However, considering the compromise between the GFHE heating rate and the HTF pressure drop along the gap, a 0.4 mm gap width is preferred. A testing loop was also set up to experimentally evaluate the GFHE capability. The testing results show that, by using 0.4 mm gap width and 500 ml/min HTF flow rate, the maximum heating rate in the working chamber of the as-made GFHE can reach 18 °C/min, and the average temperature change rates in the heating and cooling processes of the thermal cycle test were recorded as 6.5 and 5.4 °C/min, respectively. These temperature change rates can well satisfy the standard of IEC 60068-2-14:2009 and show that the GFHE developed in this work has sufficient heat exchange capacity and can be used as an ideal compact heat exchanger in small volume desktop thermal fatigue test apparatus.

  3. 40 CFR 146.23 - Operating, monitoring, and reporting requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... pressure, flow rate, and cumulative volume at least with the following frequencies: (i) Weekly for produced..., flow rate and cumulative volume at reasonable intervals no greater than 30 days. (3) A demonstration of..., and any major changes in characteristics or sources of injected fluid. Previously submitted...

  4. Choked flow of fluid nitrogen with emphasis on the thermodynamic critical region

    NASA Technical Reports Server (NTRS)

    Hendricks, R. C.; Simoneau, R. J.; Ehlers, R. C.

    1972-01-01

    Experimental measurements of critical flow rate and pressure ratio for nitrogen flowing through a nozzle are presented. Data for selected stagnation isotherms from 87.5 to 234 K with pressures to 9.3 MN/m2 are compared to an equilibrium model with real fluid properties and also a nonequilibrium model. Critical flow pressure ratio along an isotherm tends to peak while the flow rate indicates an inflection. The point is closely associated with the transposed critical temperature and represents a change in the fluid structure.

  5. Streamflow sensitivity to water storage changes across Europe

    NASA Astrophysics Data System (ADS)

    Berghuijs, Wouter R.; Hartmann, Andreas; Woods, Ross A.

    2016-03-01

    Terrestrial water storage is the primary source of river flow. We introduce storage sensitivity of streamflow (ɛS), which for a given flow rate indicates the relative change in streamflow per change in catchment water storage. ɛS can be directly derived from streamflow observations. Analysis of 725 catchments in Europe reveals that ɛS is high in, e.g., parts of Spain, England, Germany, and Denmark, whereas flow regimes in parts of the Alps are more resilient (that is, less sensitive) to storage changes. A regional comparison of ɛS with observations indicates that ɛS is significantly correlated with variability of low (R2 = 0.41), median (R2 = 0.27), and high flow conditions (R2 = 0.35). Streamflow sensitivity provides new guidance for a changing hydrosphere where groundwater abstraction and climatic changes are altering water storage and flow regimes.

  6. Effects of water flow regulation on ecosystem functioning in a Mediterranean river network assessed by wood decomposition.

    PubMed

    Abril, Meritxell; Muñoz, Isabel; Casas-Ruiz, Joan P; Gómez-Gener, Lluís; Barceló, Milagros; Oliva, Francesc; Menéndez, Margarita

    2015-06-01

    Mediterranean rivers are extensively modified by flow regulation practises along their courses. An important part of the river impoundment in this area is related to the presence of small dams constructed mainly for water abstraction purposes. These projects drastically modified the ecosystem morphology, transforming lotic into lentic reaches and increasing their alternation along the river. Hydro-morphologial differences between these reaches indicate that flow regulation can trigger important changes in the ecosystem functioning. Decomposition of organic matter is an integrative process and this complexity makes it a good indicator of changes in the ecosystem. The aim of this study was to assess the effect caused by flow regulation on ecosystem functioning at the river network scale, using wood decomposition as a functional indicator. We studied the mass loss from wood sticks during three months in different lotic and lentic reaches located along a Mediterranean river basin, in both winter and summer. Additionally, we identified the environmental factors affecting decomposition rates along the river orders. The results revealed differences in decomposition rates between sites in both seasons that were principally related to the differences between stream orders. The rates were mainly related to temperature, nutrient concentrations (NO2(-), NO3(2-)) and water residence time. High-order streams with higher temperature and nutrient concentrations exhibited higher decomposition rates compared with low-order streams. The effect of the flow regulation on the decomposition rates only appeared to be significant in high orders, especially in winter, when the hydrological characteristics of lotic and lentic habitats widely varied. Lotic reaches with lower water residence time exhibited greater decomposition rates compared with lentic reaches probably due to more physical abrasion and differences in the microbial assemblages. Overall, our study revealed that in high orders the reduction of flow caused by flow regulation affects the wood decomposition indicating changes in ecosystem functioning. Copyright © 2015 Elsevier B.V. All rights reserved.

  7. Selective Use of Optical Variables to Control Forward Speed

    NASA Technical Reports Server (NTRS)

    Johnson, Walter W.; Awe, Cynthia A.; Hart, Sandra G. (Technical Monitor)

    1994-01-01

    Previous work on the perception and control of simulated vehicle speed has examined the contributions of optical flow rate (angular visual speed) and texture, or edge rate (frequency of passing terrain objects or markings) on the perception and control of forward speed. However, these studies have not examined the ability to selectively use edge rate or flow rate. The two studies reported here show that subjects found it very difficult to arbitrarily direct attention to one or the other of these variables; but that the ability to selectively use these variables is linked to the visual contextual information about the relative validity (linkage with speed) of the two variables. The selectivity also resulted in different velocity adaptation levels for events in which flow rate and edge rate specified forward speed. Finally, the role of visual context in directing attention was further buttressed by the finding that the incorrect perception of changes in ground texture density tended to be coupled with incorrect perceptions of changes in forward speed.

  8. Prefrontal oxygenation correlates to the responses in facial skin blood flows during exposure to pleasantly charged movie.

    PubMed

    Matsukawa, Kanji; Endo, Kana; Asahara, Ryota; Yoshikawa, Miho; Kusunoki, Shinya; Ishida, Tomoko

    2017-11-01

    Our laboratory reported that facial skin blood flow may serve as a sensitive tool to assess an emotional status. Cerebral neural correlates during emotional interventions should be sought in relation to the changes in facial skin blood flow. To test the hypothesis that prefrontal activity has positive relation to the changes in facial skin blood flow during emotionally charged stimulation, we examined the dynamic changes in prefrontal oxygenation (with near-infrared spectroscopy) and facial skin blood flows (with two-dimensional laser speckle and Doppler flowmetry) during emotionally charged audiovisual challenges for 2 min (by viewing comedy, landscape, and horror movie) in 14 subjects. Hand skin blood flow and systemic hemodynamics were simultaneously measured. The extents of pleasantness and consciousness for each emotional stimulus were estimated by subjective rating from -5 (the most unpleasant; the most unconscious) to +5 (the most pleasant; the most conscious). Positively charged emotional stimulation (comedy) simultaneously decreased ( P  <   0.05) prefrontal oxygenation and facial skin blood flow, whereas negatively charged (horror) or neutral (landscape) emotional stimulation did not alter or slightly decreased them. Any of hand skin blood flow and systemic cardiovascular variables did not change significantly during positively charged emotional stimulation. The changes in prefrontal oxygenation had a highly positive correlation with the changes in facial skin blood flow without altering perfusion pressure, and they were inversely correlated with the subjective rating of pleasantness. The reduction in prefrontal oxygenation during positively charged emotional stimulation suggests a decrease in prefrontal neural activity, which may in turn elicit neurally mediated vasoconstriction of facial skin blood vessels. © 2017 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of The Physiological Society and the American Physiological Society.

  9. Development of Design Review Procedures for Army Air Pollution Abatement Projects. Volume II. Appendices.

    DTIC Science & Technology

    1980-07-01

    flow rate wet based on %02 (ACFMWX) RAO RGWO2 (Ts + 460 ) 29.92 2 2 x 530 (Pb + Ps/13.6) OPTION TWO 25. Percent oxygen in flue gas as calculated from...Flow Characteristics of Gas Stream A-29 A.3.5.1 Flow Rate A-29 A.3.5.2 Variations in Flow Rate A-30 A.3.5.3 Changes in Properties A-30 A.3.5.4 Control ...Size and Concentration B-3 B.l.l.2 Electrical Conditions B-5 B.1.1.3 Reentrainment of Dust B-7 B.l.l.4 Gas Flow Uniformity B-7 B.1.2 Flue Gas

  10. Electro-osmotically driven liquid delivery method and apparatus

    DOEpatents

    Rakestraw, David J.; Anex, Deon S.; Yan, Chao; Dadoo, Rajeev; Zare, Richard N.

    1999-01-01

    Method and apparatus for controlling precisely the composition and delivery of liquid at sub-.mu.L/min flow rate. One embodiment of such a delivery system is an electro-osmotically driven gradient flow delivery system that generates dynamic gradient flows with sub-.mu.L/min flow rates by merging a plurality of electro-osmotic flows. These flows are delivered by a plurality of delivery arms attached to a mixing connector, where they mix and then flow into a receiving means, preferably a column. Each inlet of the plurality of delivery arms is placed in a corresponding solution reservoir. A plurality of independent programmable high-voltage power supplies is used to apply a voltage program to each of the plurality of solution reservoirs to regulate the electro-osmotic flow in each delivery arm. The electro-osmotic flow rates in the delivery arms are changed with time according to each voltage program to deliver the required gradient profile to the column.

  11. Evaluation of Application Accuracy and Performance of a Hydraulically Operated Variable-Rate Aerial Application System

    USDA-ARS?s Scientific Manuscript database

    An aerial variable-rate application system consisting of a DGPS-based guidance system, automatic flow controller, and hydraulically controlled pump/valve was evaluated for response time to rapidly changing flow requirements and accuracy of application. Spray deposition position error was evaluated ...

  12. Surface-acoustic-wave (SAW) flow sensor

    NASA Astrophysics Data System (ADS)

    Joshi, Shrinivas G.

    1991-03-01

    The use of a surface-acoustic-wave (SAW) device to measure the rate of gas flow is described. A SAW oscillator heated to a suitable temperature above ambient is placed in the path of a flowing gas. Convective cooling caused by the gas flow results in a change in the oscillator frequency. A 73-MHz oscillator fabricated on 128 deg rotated Y-cut lithium niobate substrate and heated to 55 C above ambient shows a frequency variation greater than 142 kHz for flow-rate variation from 0 to 1000 cu cm/min. The output of the sensor can be calibrated to provide a measurement of volume flow rate, pressure differential across channel ports, or mass flow rate. High sensitivity, wide dynamic range, and direct digital output are among the attractive features of this sensor. Theoretical expressions for the sensitivity and response time of the sensor are derived. It is shown that by using ultrasonic Lamb waves propagating in thin membranes, a flow sensor with faster response than a SAW sensor can be realized.

  13. Surface-acoustic-wave (SAW) flow sensor.

    PubMed

    Joshi, S G

    1991-01-01

    The use of a surface-acoustic-wave (SAW) device to measure the rate of gas flow is described. A SAW oscillator heated to a suitable temperature above ambient is placed in the path of a flowing gas. Convective cooling caused by the gas flow results in a change in the oscillator frequency. A 73-MHz oscillator fabricated on 128 degrees rotated Y-cut lithium niobate substrate and heated to 55 degrees C above ambient shows a frequency variation greater than 142 kHz for flow-rate variation from 0 to 1000 cm(3)/min. The output of the sensor can be calibrated to provide a measurement of volume flow rate, pressure differential across channel ports, or mass flow rate. High sensitivity, wide dynamic range, and direct digital output are among the attractive features of this sensor. Theoretical expressions for the sensitivity and response time of the sensor are derived. It is shown that by using ultrasonic Lamb waves, propagating in thin membranes, a flow sensor with faster response than a SAW sensor can be realized.

  14. Characteristics of Evaporator with a Lipuid-Vapor Separator

    NASA Astrophysics Data System (ADS)

    Ikeguchi, Masaki; Tanaka, Naoki; Yumikura, Tsuneo

    Flow pattern of refrigerant in a heat exchanger tube changes depending on vapor quality, tube diameter, refrigerant flow rate and refrigerant properties. High flow rate causes mist flow where the quality is from 0.8 to 1.0. 1n this flow pattern, the liquid film detaches from the tube wall so that the heat flow is intervened. The heat transfer coefficient generally increases with the flow rate. But the pressure drop of refrigerant flow simultaneously increases and the region of the mist flow enlarges. In order to reduce the pressure drop and suppress the mist flow, we have developped a small liquid-vapor separator that removes the vapor from the evaporating refrigerant flow. This separator is equipped in the middle of the evaporator where the flow pattern is annular. The experiments to evaluate the effect of this separator were carried out and the following conclutions were obtained. (1) Average heat transfer coefficient increases by 30-60 %. (2) Pressure drop reduces by 20-30 %. (3) Cooling Capacity increases by 2-9 %.

  15. Dual Rate Adaptive Control for an Industrial Heat Supply Process Using Signal Compensation Approach

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Chai, Tianyou; Jia, Yao; Wang, Hong

    The industrial heat supply process (HSP) is a highly nonlinear cascaded process which uses a steam valve opening as its control input, the steam flow-rate as its inner loop output and the supply water temperature as its outer loop output. The relationship between the heat exchange rate and the model parameters, such as steam density, entropy, and fouling correction factor and heat exchange efficiency are unknown and nonlinear. Moreover, these model parameters vary in line with steam pressure, ambient temperature and the residuals caused by the quality variations of the circulation water. When the steam pressure and the ambient temperaturemore » are of high values and are subjected to frequent external random disturbances, the supply water temperature and the steam flow-rate would interact with each other and fluctuate a lot. This is also true when the process exhibits unknown characteristic variations of the process dynamics caused by the unexpected changes of the heat exchange residuals. As a result, it is difficult to control the supply water temperature and the rates of changes of steam flow-rate well inside their targeted ranges. In this paper, a novel compensation signal based dual rate adaptive controller is developed by representing the unknown variations of dynamics as unmodeled dynamics. In the proposed controller design, such a compensation signal is constructed and added onto the control signal obtained from the linear deterministic model based feedback control design. Such a compensation signal aims at eliminating the unmodeled dynamics and the rate of changes of the currently sample unmodeled dynamics. A successful industrial application is carried out, where it has been shown that both the supply water temperature and the rate of the changes of the steam flow-rate can be controlled well inside their targeted ranges when the process is subjected to unknown variations of its dynamics.« less

  16. Pump tank divider plate for sump suction sodium pumps

    DOEpatents

    George, John A.; Nixon, Donald R.

    1977-01-01

    A circular plate extends across the diameter of "sump suction" pump, with a close clearance between the edge of the plate and the wall of the pump tank. The plate is located above the pump impeller, inlet and outlet flow nozzles but below the sodium free surface and effectively divides the pump tank into two separate chambers. On change of pump speed, the close fitting flow restriction plate limits the rate of flow into or out of the upper chamber, thereby minimizing the rate of level change in the tank and permitting time for the pump cover gas pressure to be varied to maintain an essentially constant level.

  17. Field study and simulation of diurnal temperature effects on infiltration and variably saturated flow beneath an ephemeral stream

    USGS Publications Warehouse

    Dudek Ronan, Anne; Prudic, David E.; Thodal, Carl E.; Constantz, Jim

    1998-01-01

    Two experiments were performed to investigate flow beneath an ephemeral stream and to estimate streambed infiltration rates. Discharge and stream-area measurements were used to determine infiltration rates. Stream and subsurface temperatures were used to interpret subsurface flow through variably saturated sediments beneath the stream. Spatial variations in subsurface temperatures suggest that flow beneath the streambed is dependent on the orientation of the stream in the canyon and the layering of the sediments. Streamflow and infiltration rates vary diurnally: Streamflow is lowest in late afternoon when stream temperature is greatest and highest in early morning when stream temperature is least. The lower afternoon Streamflow is attributed to increased infiltration rates; evapotranspiration is insufficient to account for the decreased Streamflow. The increased infiltration rates are attributed to viscosity effects on hydraulic conductivity from increased stream temperatures. The first set of field data was used to calibrate a two-dimensional variably saturated flow model that includes heat transport. The model was calibrated to (1) temperature fluctuations in the subsurface and (2) infiltration rates determined from measured Streamflow losses. The second set of field data was to evaluate the ability to predict infiltration rates on the basis of temperature measurements alone. Results indicate that the variably saturated subsurface flow depends on downcanyon layering of the sediments. They also support the field observations in indicating that diurnal changes in infiltration can be explained by temperature dependence of hydraulic conductivity. Over the range of temperatures and flows monitored, diurnal stream temperature changes can be used to estimate streambed infiltration rates. It is often impractical to maintain equipment for determining infiltration rates by traditional means; however, once a model is calibrated using both infiltration and temperature data, only relatively inexpensive temperature monitoring can later yield infiltration rates that are within the correct order of magnitude.

  18. Identification of Carbon loss in the production of pilot-scale Carbon nanotube using gauze reactor

    NASA Astrophysics Data System (ADS)

    Wulan, P. P. D. K.; Purwanto, W. W.; Yeni, N.; Lestari, Y. D.

    2018-03-01

    Carbon loss more than 65% was the major obstacles in the Carbon Nanotube (CNT) production using gauze pilot scale reactor. The results showed that the initial carbon loss calculation is 27.64%. The calculation of carbon loss, then, takes place with various corrections parameters of: product flow rate error measurement, feed flow rate changes, gas product composition by Gas Chromatography Flame Ionization Detector (GC FID), and the carbon particulate by glass fiber filters. Error of product flow rate due to the measurement with bubble soap gives calculation error of carbon loss for about ± 4.14%. Changes in the feed flow rate due to CNT growth in the reactor reduce carbon loss by 4.97%. The detection of secondary hydrocarbon with GC FID during CNT production process reduces carbon loss by 5.14%. Particulates carried by product stream are very few and merely correct the carbon loss about 0.05%. Taking all the factors into account, the amount of carbon loss within this study is (17.21 ± 4.14)%. Assuming that 4.14% of carbon loss is due to the error measurement of product flow rate, the amount of carbon loss is 13.07%. It means that more than 57% of carbon loss within this study is identified.

  19. Groundwater Flow Through a Constructed Treatment Wetland

    DTIC Science & Technology

    2002-03-01

    sediments or has the water found preferential flow paths? (2) Does the behavior of groundwater flow change with varying loading rates or environmental...surface of the wetland. Water flows through a subsurface flow wetland in a similar fashion as groundwater flows through an aquifer. The concept is...circuiting of the wetland media. Groundwater Flow Various physical properties influence the flow of water through soil. In wetlands, the type of soil

  20. Growth rate of plasma-synthesized vertically aligned carbon nanofibers

    NASA Astrophysics Data System (ADS)

    Merkulov, Vladimir I.; Melechko, A. V.; Guillorn, M. A.; Lowndes, D. H.; Simpson, M. L.

    2002-08-01

    Vertically aligned carbon nanofibers (VACNFs) were synthesized by direct-current plasma enhanced chemical vapor deposition using acetylene and ammonia as the gas source. The mechanisms responsible for changing the nanofiber growth rate were studied and phenomenological models are proposed. The feedstock for VACNF growth is suggested to consist mainly of radicals formed in the plasma and not the unexcited acetylene gas molecules. The growth rate is shown to increase dramatically by changing the radical transport mechanism from diffusive to forced flow, which was accomplished by increasing the gas flow in the direction perpendicular to the substrate.

  1. Influences of exit and stair conditions on human evacuation in a dormitory

    NASA Astrophysics Data System (ADS)

    Lei, Wenjun; Li, Angui; Gao, Ran; Wang, Xiaowei

    2012-12-01

    Evacuation processes of students are investigated by experiment and simulation. The experiment is performed for students evacuating from a dormitory with an exit and stairs. FDS+Evac is proposed to simulate the exit and stair dynamics of occupant evacuation. Concerning the exit and stair widths, we put forward some useful standpoints. Good agreement is achieved between the predicted results and experimental results. With the increase of exit width, a significant stratification phenomenon will be found in flow rate. Stratification phenomenon is that two different stable flow rates will emerge during the evacuation. And the flow rate curve looks like a ladder. The larger the exit width, the earlier the stratification phenomenon appears. When exit width is more than 2.0 m, the flow rate of each exit width is divided into two stable stages, and the evacuation times show almost no change. The judgment that the existence of stairs causes flow stratification is reasonable. By changing the width of the stairs, we proved that judgment. The smaller the width of BC, the earlier the stratification appears. We found that scenario 5 is the most adverse circumstance. Those results are helpful in performance-based design of buildings.

  2. Unraveling the relationship between arterial flow and intra-aneurysmal hemodynamics.

    PubMed

    Morales, Hernán G; Bonnefous, Odile

    2015-02-26

    Arterial flow rate affects intra-aneurysmal hemodynamics but it is not clear how their relationship is. This uncertainty hinders the comparison among studies, including clinical evaluations, like a pre- and post-treatment status, since arterial flow rates may differ at each time acquisition. The purposes of this work are as follows: (1) To study how intra-aneurysmal hemodynamics changes within the full physiological range of arterial flow rates. (2) To provide characteristic curves of intra-aneurysmal velocity, wall shear stress (WSS) and pressure as functions of the arterial flow rate. Fifteen image-based aneurysm models were studied using computational fluid dynamics (CFD) simulations. The full range of physiological arterial flow rates reported in the literature was covered by 11 pulsatile simulations. For each aneurysm, the spatiotemporal-averaged blood flow velocity, WSS and pressure were calculated. Spatiotemporal-averaged velocity inside the aneurysm linearly increases as a function of the mean arterial flow (minimum R(2)>0.963). Spatiotemporal-averaged WSS and pressure at the aneurysm wall can be represented by quadratic functions of the arterial flow rate (minimum R(2)>0.996). Quantitative characterizations of spatiotemporal-averaged velocity, WSS and pressure inside cerebral aneurysms can be obtained with respect to the arterial flow rate. These characteristic curves provide more information of the relationship between arterial flow and aneurysm hemodynamics since the full range of arterial flow rates is considered. Having these curves, it is possible to compare experimental studies and clinical evaluations when different flow conditions are used. Copyright © 2015 Elsevier Ltd. All rights reserved.

  3. Hemodynamics of a functional centrifugal-flow total artificial heart with functional atrial contraction in goats.

    PubMed

    Shiga, Takuya; Shiraishi, Yasuyuki; Sano, Kyosuke; Taira, Yasunori; Tsuboko, Yusuke; Yamada, Akihiro; Miura, Hidekazu; Katahira, Shintaro; Akiyama, Masatoshi; Saiki, Yoshikatsu; Yambe, Tomoyuki

    2016-03-01

    Implantation of a total artificial heart (TAH) is one of the therapeutic options for the treatment of patients with end-stage biventricular heart failure. There is no report on the hemodynamics of the functional centrifugal-flow TAH with functional atrial contraction (fCFTAH). We evaluated the effects of pulsatile flow by atrial contraction in acute animal models. The goats received fCFTAH that we created from two centrifugal-flow ventricular assist devices. Some hemodynamic parameters maintained acceptable levels: heart rate 115.5 ± 26.3 bpm, aortic pressure 83.5 ± 10.1 mmHg, left atrial pressure 18.0 ± 5.9 mmHg, pulmonary pressure 28.5 ± 9.7 mmHg, right atrial pressure 13.6 ± 5.2 mmHg, pump flow 4.0 ± 1.1 L/min (left) 3.9 ± 1.1 L/min (right), and cardiac index 2.13 ± 0.14 L/min/m(2). fCFTAH with atrial contraction was able to maintain the TAH circulation by forming a pulsatile flow in acute animal experiments. Taking the left and right flow rate balance using the low internal pressure loss of the VAD pumps may be easier than by other pumps having considerable internal pressure loss. We showed that the remnant atrial contraction effected the flow rate change of the centrifugal pump, and the atrial contraction waves reflected the heart rate. These results indicate that remnant atria had the possibility to preserve autonomic function in fCFTAH. We may control fCFTAH by reflecting the autonomic function, which is estimated with the flow rate change of the centrifugal pump.

  4. 40 CFR 721.91 - Computation of estimated surface water concentrations: Instructions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... shall be computed for each site using the stream flow rate appropriate for the site according to... computing the equation, the number of kilograms released, and receiving stream flow. (a) Number of kilograms... chemical changes and/or changes in location, temperature, pressure, physical state, or similar...

  5. Effects of seawater flow rate and evaporation temperature on performance of Sherbet type ice making machine

    NASA Astrophysics Data System (ADS)

    Son, C. H.; Yoon, J. I.; Choi, K. H.; Lee, H. K.; Lee, K. S.; Moon, C. G.; Seol, S. H.

    2018-01-01

    This study analyzes performance of the sherbet type ice making machine using seawater with respect to seawater volumetric flow rate, evaporation temperature, cooling water inlet and seawater inlet temperature as variables. Cooling water inlet and seawater inlet temperature are set considering average temperature of South Korea and the equator regions. Volumetric flow rate of seawater range is 0.75-1.75 LPM in this experiment. The results obtained from the experiment are as follows. As the seawater volumetric flow rate increases, or seawater inlet temperature increases, evaporation capacity tends to increase. At the point of seawater inlet temperature of 27°C and volumetric flow rate of 1.0LPM, evaporation capacity is over 2kW. On the other hand, results of COP change tendency are different from that of evaporation capacity. It appears to increase until volumetric flow rate of 1.0LPM, and decrease gradually from volumetric flow rate of 1.5LPM. This is due to the increase of compressor work to keep the evaporation pressure in accordance with the temperature of heat source. As the evaporation temperature decreases from -8 to -15°C, the evaporation capacity increases, but the COP decreases.

  6. Flow rate-pressure drop relation for deformable shallow microfluidic channels

    NASA Astrophysics Data System (ADS)

    Christov, Ivan C.; Cognet, Vincent; Shidhore, Tanmay C.; Stone, Howard A.

    2018-04-01

    Laminar flow in devices fabricated from soft materials causes deformation of the passage geometry, which affects the flow rate--pressure drop relation. For a given pressure drop, in channels with narrow rectangular cross-section, the flow rate varies as the cube of the channel height, so deformation can produce significant quantitative effects, including nonlinear dependence on the pressure drop [{Gervais, T., El-Ali, J., G\\"unther, A. \\& Jensen, K.\\ F.}\\ 2006 Flow-induced deformation of shallow microfluidic channels.\\ \\textit{Lab Chip} \\textbf{6}, 500--507]. Gervais et. al. proposed a successful model of the deformation-induced change in the flow rate by heuristically coupling a Hookean elastic response with the lubrication approximation for Stokes flow. However, their model contains a fitting parameter that must be found for each channel shape by performing an experiment. We present a perturbation approach for the flow rate--pressure drop relation in a shallow deformable microchannel using the theory of isotropic quasi-static plate bending and the Stokes equations under a lubrication approximation (specifically, the ratio of the channel's height to its width and of the channel's height to its length are both assumed small). Our result contains no free parameters and confirms Gervais et. al.'s observation that the flow rate is a quartic polynomial of the pressure drop. The derived flow rate--pressure drop relation compares favorably with experimental measurements.

  7. Modelling the growth Rate of Algal in sediment-laden flow

    NASA Astrophysics Data System (ADS)

    Li, H.

    2017-12-01

    Phytoplankton plays an important role as a primary producer in aquatic ecosystems. Fluid dynamics can affect the growth of algae in a number of ways and can be divided into two categories. On the one hand the advection and diffusion processes may disrupt the vertical migration of phytoplankton. On the other hand hydrodynamic effects of sediment suspension which can affect algal growth, by releasing nutrients and reducing light intensity. Natural water generally contains sediment. Therefore, when the flow enters the lake, it will cause a change in the phytoplankton community at the junction. Few people have studied the effects of sediment-laden flows to algal growth rates. In this project, Baiyangdian was chosen as the key research area to study the effect of sediment-laden flow on the growth rate of algae. And we conducted a microcosmic experiment in the laboratory to simulate the effect of sediment-laden flow on the growth rate of algae, and constructed a numerical model for the growth rate of algae in sediment-laden flow.

  8. Phase change paint tests on Rockwell orbiter/tank and orbiter alone configurations (OH3A/OH3B)

    NASA Technical Reports Server (NTRS)

    Quan, M.; Craig, C.

    1974-01-01

    Wind tunnel tests were conducted on scale models of the space shuttle orbiter and external tank. The tests were designed to determine the basic heating rate and interference effects on the orbiter-tank configuration and to analyze the effectiveness of the thermal protective system on the reentry vehicle. The phase change paint techniques were used to determine areodynamic heating rates. Oil flow and schlieren photographs were used for flow visualization.

  9. Investigation of the effect of wall friction on the flow rate in 2D and 3D Granular Flow

    NASA Astrophysics Data System (ADS)

    Carballo-Ramirez, Brenda; Pleau, Mollie; Easwar, Nalini; Birwa, Sumit; Shah, Neil; Tewari, Shubha

    We have measured the mass flow rate of spherical steel spheres under gravity in vertical, straight-walled 2 and 3-dimensional hoppers, where the flow velocity is controlled by the opening size. Our measurements focus on the role of friction and its placement along the walls of the hopper. In the 2D case, an increase in the coefficient of static friction from μ = 0.2 to 0.6 is seen to decrease the flow rate significantly. We have changed the placement of frictional boundaries/regions from the front and back walls of the 2D hopper to the side walls and floor to investigate the relative importance of the different regions in determining the flow rate. Fits to the Beverloo equation show significant departure from the expected exponent of 1.5 in the case of 2D flow. In contrast, 3D flow rates do not show much dependence on wall friction and its placement. We compare the experimental data to numerical simulations of gravity driven hopper granular flow with varying frictional walls constructed using LAMMPS*. *http://lammps.sandia.gov Supported by NSF MRSEC DMR 0820506.

  10. Association between chewing-stimulated salivary flow under the effects of atropine and mixing ability assessed using a color-changeable chewing gum.

    PubMed

    Kubota, Chieko; Kanazawa, Manabu; Hama, Yohei; Komagamine, Yuriko; Minakuchi, Shunsuke

    2017-10-01

    To assess the time course of chewing-stimulated salivary flow after oral atropine administration, and determine the association between chewing-stimulated salivary flow and mixing ability using color-changeable chewing gum in dentate adults. Ten healthy dentate adults were administered 1mg oral atropine to induce mouth dryness. The subjects' chewing-stimulated salivary flow was assessed using the Saxon test. They were then asked to rinse their mouth with tap water for 15s, and to chew on color-changeable chewing gum for 60s at a constant rate of 60 cycles per min. This procedure was performed before, and at 10-min intervals for up to 120min after the atropine administration. The experiment was repeated after 1 week. Steel's test was used to compare the chewing-stimulated salivary flow rates at each time point after atropine administration with the baseline value. The effect of the stimulated salivary flow rates on the degree of color change was analyzed using linear mixed effects models, with the stimulated salivary flow rates as fixed factors and subjects as the random factor. Chewing-stimulated salivary flow showed a significant decrease from 50 to 120min after oral atropine administration (P<0.05) and the amount of chewing-stimulated salivary flow had a significant effect on the color change of the color-changeable chewing gum (P<0.001). We observed a decrease in stimulated salivary flow after orally administering 1mg atropine, and a positive association between mixing ability using color-changeable chewing gum and chewing-stimulated salivary flow in dentate subjects. Copyright © 2017 Japan Prosthodontic Society. Published by Elsevier Ltd. All rights reserved.

  11. Premixed Edge-Flames in Spatially-Varying Straining Flows

    NASA Technical Reports Server (NTRS)

    Liu, Jian-Bang; Ronney, Paul D.

    1999-01-01

    Flames subject to temporally and spatially uniform hydrodynamic strain are frequently used to model the local interactions of flame fronts with turbulent flow fields (Williams, 1985; Peters, 1986; Bradley, 1992). The applicability of laminar flamelet models in strongly turbulent flows have been questioned recently (Shay and Ronney, 1998) because in turbulent flows the strain rate (sigma) changes at rates comparable to sigma itself and the scale over which the flame front curvature and sigma changes is comparable to the curvature scale itself. Therefore quasi-static, local models of turbulent strain and curvature effects on laminar flamelets may not be accurate under conditions where the strain and curvature effects are most significant. The purpose of this study is to examine flames in spatially-varying strain and compare their properties to those of uniformly strained flames.

  12. Balancing tissue perfusion demands: cardiovascular dynamics of Cancer magister during exposure to low salinity and hypoxia.

    PubMed

    McGaw, Iain J; McMahon, Brian R

    2003-01-01

    Decapod crustaceans inhabit aquatic environments that are frequently subjected to changes in salinity and oxygen content. The physiological responses of decapod crustaceans to either salinity or hypoxia are well documented; however, there are many fewer reports on the physiological responses during exposure to these parameters in combination. We investigated the effects of simultaneous and sequential combinations of low salinity and hypoxia on the cardiovascular physiology of the Dungeness crab, Cancer magister. Heart rate, as well as haemolymph flow rates through the anterolateral, hepatic, sternal and posterior arteries were measured using a pulsed-Doppler flowmeter. Summation of flows allowed calculation of cardiac output and division of this by heart rate yielded stroke volume. When hypoxia and low salinity were encountered simultaneously, the observed changes in cardiac properties tended to be a mix of both factors. Hypoxia caused a bradycardia, whereas exposure to low salinity was associated with a tachycardia. However, the hypoxic conditions had the dominant effect on heart rate. Although hypoxia caused an increase in stroke volume of the heart, the low salinity had a more pronounced effect, causing an overall decrease in stroke volume. The patterns of haemolymph flow through the arterial system also varied when hypoxia and low salinity were offered together. The resulting responses were a mix of those resulting from exposure to either parameter alone. When low salinity and hypoxia were offered sequentially, the parameter experienced first tended to have the dominant effect on cardiac function and haemolymph flows. Low salinity exposure was associated with an increase in heart rate, a decrease in stroke volume and cardiac output, and a concomitant decrease in haemolymph flow rates. Subsequent exposure to hypoxic conditions caused a slight decrease in rate, but other cardiovascular variables were largely unaffected. In contrast, when low salinity followed acclimation to hypoxic conditions, apart from an increased heart rate, there were no other cardiovascular changes associated with the low salinity episode. The implications of these changes in cardiovascular dynamics are discussed in relation to physiological mechanisms and the ecology of decapod crustaceans, in hypoxic or low salinity environments. Copyright 2003, Wiley-Liss, Inc.

  13. Combined Flow Abstraction and Climate Change Impacts on an Aggrading Alpine River

    NASA Astrophysics Data System (ADS)

    Bakker, M.; Costa, A.; Silva, T. A.; Stutenbecker, L.; Girardclos, S.; Loizeau, J.-L.; Molnar, P.; Schlunegger, F.; Lane, S. N.

    2018-01-01

    Recent climatic warming and associated glacial retreat may have a large impact on sediment release and transfer in Alpine river basins. Concurrently, the sediment transport capacity of many European Alpine streams is affected by hydropower exploitation, notably where flow is abstracted but the sediment supply downstream is maintained. Here, we investigate the combined effects of climate change and flow abstraction on morphodynamics and sediment transfer in the Borgne River, Switzerland. From photogrammetrically derived historical Digital Elevation Models (DEMs), we find considerable net aggradation of the braided river bed (up to 5 m) since the onset of flow abstraction in 1963. Reaches responded through bed level steepening which was strongest in the upper most reach. Widespread aggradation however did not commence until the onset of glacier retreat in the late 1980s and the dry and warm years of the early 1990s. Upstream flow intake data shows that this aggradation coincided with an increase in sediment supply, although aggradation accounts for no more than 25% of supplied material. The remainder was transferred through the studied reaches. Estimations of bed load transport capacity indicate that flow abstraction reduces transport capacity by 1-2 orders of magnitude. While residual transport rates vary with morphological evolution, they are in the same order of magnitude as the sediment supply rates, which is why significant transport remains. However, the reduction in transport capacity makes the system more sensitive to short-term (annual) changes in climate-driven hydrological variability and climate-induced changes in intake management and sediment delivery rates.

  14. Construction and geometric stability of physiological flow rate wall-less stenosis phantoms.

    PubMed

    Ramnarine, K V; Anderson, T; Hoskins, P R

    2001-02-01

    Wall-less flow phantoms are preferred for ultrasound (US) because tissue-mimicking material (TMM) with good acoustical properties can be made and cast to form anatomical models. The construction and geometrical stability of wall-less TMM flow phantoms is described using a novel method of sealing to prevent leakage of the blood-mimicking fluid (BMF). Wall-less stenosis flow models were constructed using a robust agar-based TMM and sealed using reticulated foam at the inlet and outlet tubes. There was no BMF leakage at the highest flow rate of 2.8 L/min in 0%, 35% and 57% diameter reduction stenoses models. Failure of the 75% stenosis model, due to TMM fracture, occurred at maximum flow rate of 2 L/min (mean velocity 10 m/s within the stenosis). No change of stenosis geometry was measured over 4 days. The construction is simple and effective and extends the possibility for high flow rate studies using robust TMM wall-less phantoms.

  15. Real-time measurement of flow rate in microfluidic devices using a cantilever-based optofluidic sensor.

    PubMed

    Cheri, Mohammad Sadegh; Latifi, Hamid; Sadeghi, Jalal; Moghaddam, Mohammadreza Salehi; Shahraki, Hamidreza; Hajghassem, Hasan

    2014-01-21

    Real-time and accurate measurement of flow rate is an important reqirement in lab on a chip (LOC) and micro total analysis system (μTAS) applications. In this paper, we present an experimental and numerical investigation of a cantilever-based optofluidic flow sensor for this purpose. Two sensors with thin and thick cantilevers were fabricated by engraving a 2D pattern of cantilever/base on two polymethylmethacrylate (PMMA) slabs using a CO2 laser system and then casting a 2D pattern with polydimethylsiloxane (PDMS). The basic working principle of the sensor is the fringe shift of the Fabry-Pérot (FP) spectrum due to a changing flow rate. A Finite Element Method (FEM) is used to solve the three dimensional (3D) Navier-Stokes and structural deformation equations to simulate the pressure distribution, velocity and cantilever deflection results of the flow in the channel. The experimental results show that the thin and thick cantilevers have a minimum detectable flow change of 1.3 and 4 (μL min(-1)) respectively. In addition, a comparison of the numerical and experimental deflection of the cantilever has been done to obtain the effective Young's modulus of the thin and thick PDMS cantilevers.

  16. Effect of argon ion activity on the properties of Y 2O 3 thin films deposited by low pressure PACVD

    NASA Astrophysics Data System (ADS)

    Barve, S. A.; Jagannath; Deo, M. N.; Kishore, R.; Biswas, A.; Gantayet, L. M.; Patil, D. S.

    2010-10-01

    Yttrium oxide thin films are deposited by microwave electron cyclotron resonance (ECR) plasma assisted metal organic chemical vapour deposition process using an indegeneously developed Y(thd) 3 {(2,2,6,6-tetramethyl-3,5-heptanedionate)yttrium} precursor. Depositions were carried out at two different argon gas flow rates keeping precursor and oxygen gas flow rate constant. The deposited coatings are characterized by X-ray photoelectron spectroscopy (XPS), glancing angle X-ray diffraction (GIXRD) and infrared spectroscopy. Optical properties of the films are studied by spectroscopic ellipsometry. Hardness and elastic modulus of the films are measured by load depth sensing nanoindentation technique. Stability of the film and its adhesion with the substrate is inferred from the nanoscratch test. It is shown here that, the change in the argon gas flow rates changes the ionization of the gas in the microwave ECR plasma and imposes a drastic change in the characteristics like composition, structure as well as mechanical properties of the deposited film.

  17. Paper to Electronic Questionnaires: Effects on Structured Questionnaire Forms

    NASA Technical Reports Server (NTRS)

    Trujillo, Anna C.

    2009-01-01

    With the use of computers, paper questionnaires are being replaced by electronic questionnaires. The formats of traditional paper questionnaires have been found to effect a subject's rating. Consequently, the transition from paper to electronic format can subtly change results. The research presented begins to determine how electronic questionnaire formats change subjective ratings. For formats where subjects used a flow chart to arrive at their rating, starting at the worst and middle ratings of the flow charts were the most accurate but subjects took slightly more time to arrive at their answers. Except for the electronic paper format, starting at the worst rating was the most preferred. The paper and electronic paper versions had the worst accuracy. Therefore, for flowchart type of questionnaires, flowcharts should start at the worst rating and work their way up to better ratings.

  18. Evidence for enhanced debris flow activity in the Northern Calcareous Alps since the 1980s (Plansee, Austria)

    NASA Astrophysics Data System (ADS)

    Dietrich, Andreas; Krautblatter, Michael

    2016-04-01

    From 1950 to 2011 almost 80.000 people lost their lives through the occurrence of debris flow events (Dowling and Santi, 2014). Debris flows occur in all alpine regions due to intensive rainstorms and mobilisable loose debris. Due to their susceptible lithology, the Northern Calcareous Alps are affected by a double digit number of major hazard events per year. Some authors hypothesised a relation between an increasing frequency of heavy rainstorms and an increasing occurrence of landslides in general (Beniston and Douglas, 1996) and debris flows in special (Pelfini and Santilli, 2008), but yet there is only limited evidence. The Plansee catchment in the Ammergauer Alps consists of intensely jointed Upper Triassic Hauptdolomit lithology and therefore shows extreme debris flow activity. To investigate this activity in the last decades, the temporal and spatial development of eight active debris flow fans is examined with GIS and field mapping. The annual rates since the late 1940s are inferred accurately by using aerial photos from 1947, 1952, 1971, 1979, 1987, 2000 and 2010. These rates are compared to the mean Holocene/Lateglacial debris flow volume derived from the most prominent cone. The contact with the underlying till is revealed by electrical resistivity tomography (ERT). It shows that the mean annual debris flow volume has increased there by a factor of 10 from 1947-1952 (0.23 ± 0.07 10³m³/yr) to 1987-2000 (2.41 ± 0.66 10³m³/yr). A similar trend can be seen on all eight fans: mean post-1980 rates exceed pre-1980 rates by a factor of more than three. This increasing debris flow activity coincides with an enhanced rainstorm (def. 35 mm/d) frequency recorded at the nearest meteorological station. Since 1921 the frequency of heavy rainstorms has increased there on average by 10% per decade. Recent debris flow rates are also 2-3 times higher compared to mean Holocene/Lateglacial rates. Furthermore, we state a strong correlation between the non-vegetated catchment area and the annual debris flow volume. This might indicate a decadal positive feedback between enhanced rainstorm frequency and the occurrence of debris flows. The study contributes to a better understanding of the sensitivity of alpine catchments to heavy rainfall events in the context of climate change. Beniston, M., Douglas, G.F., 1996. Impacts of climate change on mountain regions. In: Watson, R.T., Zinyowera, M.C., Moss, R.H., Dokken, D.J. (Eds.), Climate Change 1995. Impacts, Adaptations and Mitigation of Climate Change: Scientific-Technical Analysis. Cambridge Univ. Press, Cambridge, pp. 191-213. Dowling, C.A., Santi, P.M., 2014. Debris flows and their toll on human life: a global analysis of debris-flow fatalities from 1950 to 2011. Nat. Hazards 71, 203-227. doi: 10.1007/s11069-013-0907-4 Pelfini, M., Santilli, M., 2008. Frequency of debris flows and their relation with precipitation: A case study in the Central Alps, Italy. Geomorphology 101, 721-730. doi:10.1016/j.geomorph.2008.04.002

  19. Dynamic flow modeling of riverine amphibian habitat with application to regulated flow management

    Treesearch

    S. Yarnell; A. Lind; J. Mount

    2012-01-01

    In regulated rivers, relicensing of hydropower projects can provide an opportunity to change flow regimes and reduce negative effects on sensitive aquatic biota. The volume of flow, timing and ramping rate of spring spills, and magnitude of aseasonal pulsed flows have potentially negative effects on the early life stages of amphibians, such as the Foothill yellow-...

  20. Phasic changes in human right coronary blood flow before and after repair of aortic insufficiency.

    PubMed

    Folts, J D; Rowe, G G; Kahn, D R; Young, W P

    1979-02-01

    We have shown previously that acute aortic insufficiency in chronically instrumented dogs reverses the normally high ratio of diastolic to systolic coronary blood flow. Phasic blood flow in the dominant right coronary artery was measured directly with an electromagnetic flow meter during surgery in eight patients with severe aortic insufficiency before and after relacement of the aortic valve. Before the insufficiency was eliminated, right coronary flow average 116 +/- 37 ml./minute and the diastolic to systolic flow ratio was 0.88 +/- 17. Mean arterial blood pressure averaged 106 +/- 17 mm. Hg, heart rate 84 +/- 19 beats/minute, and mean diastolic pressure averaged 67 +/- 10 mm. Hg. After the aortic valve was replaced with an average heart rate of 90 +/- 15 and mean blood pressure of 103 +/- 13 mm. Hg, the average right coronary blood flow increased to 180 +/- 40 ml./minute with a D/S ratio of 2.18 +/- 0.8. In all cases the right coronary blood flow increased after the aortic insufficiency was eliminated surgically. Right coronary flow probably increased because of the improved diastolic perfusion pressure and the change from predominantly systolic to diastolic coronary flow.

  1. Control of skin blood flow, sweating, and heart rate - Role of skin vs. core temperature

    NASA Technical Reports Server (NTRS)

    Wyss, C. R.; Brengelmann, G. L.; Johnson, J. M.; Rowell, L. B.; Niederberger, M.

    1974-01-01

    A study was conducted to generate quantitative expressions for the influence of core temperature, skin temperature, and the rate of change of skin temperature on sweat rate, skin blood flow, and heart rate. A second goal of the study was to determine whether the use of esophageal temperature rather than the right atrial temperature as a measure of core temperature would lead to different conclusions about the control of measured effector variables.

  2. Schlieren flow visualization of helium atmospheric plasma jet and influence of the gas flow rate and applied voltage frequency

    NASA Astrophysics Data System (ADS)

    Borghei, S. M.; Vaziri, N.; Alibabaei, S.

    2018-03-01

    We used schlieren photography to visualize the influence of gas flow rates of 1, 2.5, 5, 10 L/min and of the applied voltage frequency on a helium atmospheric plasma jet induced at the nozzle of a capillary tube. The expansion of the gas in the surrounding medium (air) was analyzed in the two different modes – plasma on/plasma off. Changes in the above parameters affect the gas flow regime and the hydrodynamics of the jet.

  3. Flow of sand and a variable mass Atwood machine

    NASA Astrophysics Data System (ADS)

    Flores, José; Solovey, Guillermo; Gil, Salvador

    2003-07-01

    We discuss a simple and inexpensive apparatus that lets us measure the instantaneous flow rate of granular media, such as sand, in real time. The measurements allow us to elucidate the phenomenological laws that govern the flow of granular media through an aperture. We use this apparatus to construct a variable mass system and study the motion of an Atwood machine with one weight changing in time in a controlled manner. The study illustrates Newton's second law for variable mass systems and lets us investigate the dependence of the flow rate on acceleration.

  4. Maple sap uptake, exudation, and pressure changes correlated with freezing exotherms and thawing endotherms.

    PubMed

    Tyree, M T

    1983-10-01

    Sap flow rates and sap pressure changes were measured in dormant sugar maple trees (Acer saccharum Marsh.). In the forest, sap flow rates and pressure changes were measured from tap holes drilled into tree trunks in mature trees and sap flow rates were measured from the base of excised branches. Excised branches were also brought into the laboratory where air temperature could be carefully controlled in a refrigerated box and sap flow rates and sap pressures were measured from the cut base of the branches.Under both forest and laboratory conditions, sap uptake occurred as the wood temperature declined but much more rapid sap uptake correlated with the onset of the freezing exotherm. When sap pressures were measured under conditions of negligible volume displacement, the sap pressure rapidly fell to -60 to -80 kilopascals at the start of the freezing exotherm. The volume of water uptake and the rate of uptake depended on the rate of freezing. A slow freezing rate correlated with a large volume of water uptake, a fast freezing rate induced a smaller volume of water uptake. The volume of water uptake ranged from 0.02 to 0.055 grams water per gram dry weight of sapwood. The volume of water exuded after thawing was usually less than the volume of uptake so that after several freezing and thawing cycles the sapwood water content increased from 0.7 to 0.8 grams water per gram dry weight.These results are discussed in terms of a physical model of the mechanism of maple sap uptake and exudation first proposed by P. E. R. O'Malley. The proposed mechanism of sap uptake is by vapor distillation in air filled wood fiber lumina during the freezing of minor branches. Gravity and pressurized air bubbles (compressed during freezing) cause sap flow from the canopy down the tree after the thaw.

  5. Maple Sap Uptake, Exudation, and Pressure Changes Correlated with Freezing Exotherms and Thawing Endotherms 1

    PubMed Central

    Tyree, Melvin T.

    1983-01-01

    Sap flow rates and sap pressure changes were measured in dormant sugar maple trees (Acer saccharum Marsh.). In the forest, sap flow rates and pressure changes were measured from tap holes drilled into tree trunks in mature trees and sap flow rates were measured from the base of excised branches. Excised branches were also brought into the laboratory where air temperature could be carefully controlled in a refrigerated box and sap flow rates and sap pressures were measured from the cut base of the branches. Under both forest and laboratory conditions, sap uptake occurred as the wood temperature declined but much more rapid sap uptake correlated with the onset of the freezing exotherm. When sap pressures were measured under conditions of negligible volume displacement, the sap pressure rapidly fell to −60 to −80 kilopascals at the start of the freezing exotherm. The volume of water uptake and the rate of uptake depended on the rate of freezing. A slow freezing rate correlated with a large volume of water uptake, a fast freezing rate induced a smaller volume of water uptake. The volume of water uptake ranged from 0.02 to 0.055 grams water per gram dry weight of sapwood. The volume of water exuded after thawing was usually less than the volume of uptake so that after several freezing and thawing cycles the sapwood water content increased from 0.7 to 0.8 grams water per gram dry weight. These results are discussed in terms of a physical model of the mechanism of maple sap uptake and exudation first proposed by P. E. R. O'Malley. The proposed mechanism of sap uptake is by vapor distillation in air filled wood fiber lumina during the freezing of minor branches. Gravity and pressurized air bubbles (compressed during freezing) cause sap flow from the canopy down the tree after the thaw. PMID:16663208

  6. Considerations in Managing the Fill Rate of the Grand Ethiopian Renaissance Dam Reservoir Using a System Dynamics Approach.

    NASA Technical Reports Server (NTRS)

    Keith, Bruce; Ford, David N.; Horton, Radley M.

    2016-01-01

    The purpose of this study is to evaluate simulated fill rate scenarios for the Grand Ethiopian Renaissance Dam while taking into account plausible climate change outcomes for the Nile River Basin. The region lacks a comprehensive equitable water resource management strategy, which creates regional security concerns and future possible conflicts. We employ climate estimates from 33 general circulation models within a system dynamics model as a step in moving toward a feasible regional water resource management strategy. We find that annual reservoir fill rates of 8-15% are capable of building hydroelectric capacity in Ethiopia while concurrently ensuring a minimum level of stream flow disruption into Egypt before 2039. Insofar as climate change estimates suggest a modest average increase in stream flow into the Aswan, climate changes through 2039 are unlikely to affect the fill rate policies. However, larger fill rates will have a more detrimental effect on stream flow into the Aswan, particularly beyond a policy of 15%. While this study demonstrates that a technical solution for reservoir fill rates is feasible, the corresponding policy challenge is political. Implementation of water resource management strategies in the Nile River Basin specifically and Africa generally will necessitate a national and regional willingness to cooperate.

  7. Topographic Effects on Geologic Mass Movements

    NASA Technical Reports Server (NTRS)

    Baloga, Stephen M.; Frey, Herbert (Technical Monitor)

    2000-01-01

    This report describes research directed toward understanding the response of volcanic lahars and lava flows to changes in the topography along the path of the flow. We have used a variety of steady-state and time-dependent models of lahars and lava flows to calculate the changes in flow dynamics due to variable topography. These models are based on first-order partial differential equations for the local conservation of volume. A global volume conservation requirement is also imposed to determine the extent of the flow as a function of time and the advance rate. Simulated DEMs have been used in this report.

  8. Analysis of the dynamics of renal vascular resistance and urine flow rate in the cat following electrical stimulation of the renal nerves.

    PubMed

    Celler, B G; Stella, A; Golin, R; Zanchetti, A

    1996-08-01

    In ten sino aortic denervated, vagotomized and aneasthetized cats, renal efferent nerves were stimulated for 30 s with trains of constant current pulses at frequencies in the range 5-30 Hz. The arterial pressure, heart rate, urine flow rate (electronic drop counter) and renal blood flow (electromagnetic technique) were recorded. Subsequent computer processing gave the true means of renal artery pressure (MRAP) and renal blood flow (MRBF) and hence the renal vascular resistance (MRVR), over each cardiac cycle. Recovery of MRVR after the end of stimulation exhibited two distinct time constants. The fast component had a time constant of 2.03 +/- 0.26 s and represented 60.2 +/- 1.71% of the recovery. The time constant of the slower component was 14.1 +/- 1.9 s and represented 36.0 +/- 1.6% of the recovery. The relationship between MRVR and stimulus frequency was sigmoidal with maximum sensitivity at stimulus frequencies of 12.6 +/- 0.76 Hz. Changes in urine flow rate, in contrast, followed a hyperbolic function with maximum response sensitivity occurring at very low stimulus frequencies. Changes in urine flow rate were 50% complete at stimulus frequencies of 5 Hz. Identification of two distinct components in the relaxation phase of renal vascular resistance leads to a reasonable hypothesis that 60% of total renal vascular resistance may lie proximal to the glomerulus, whereas 36% may be accounted for by the efferent arterioles.

  9. [Effects of different irrigations on the water physiological characteristics of Haloxylon ammodendron in Taklimakan Desert hinterland].

    PubMed

    Xie, Ting-ting; Zhang, Xi-ming; Liang, Shao-min; Shan, Li-shan; Yang, Xiao-lin; Hua, Yong-hui

    2008-04-01

    By using heat-balance stem flow gauge and press chamber, the water physiological characteristics of Haloxylon ammodendron under different irrigations in Taklimakan Desert hinterland were measured and analyzed. The results indicated that the diurnal variation curve of H. ammodendron stem sap flow varied with irrigations. When irrigated 35 and 24.5 kg x plant(-1) once time, the diurnal variation of stem sap flow changed in single peak curve and the variation extent was higher; while irrigated 14 kg x plant(-1) once time, the diurnal variation changed in two-peak curve and the variation extent was small. With the decrease of irrigations, the average daily sap flow rate and the daily water consumption of H. ammodendron decreased gradually, the dawn and postmeridian water potential also had a gradual decrease, and the correlations of stem sap flow with total radiation, air temperature, relative humidity, and wind speed enhanced. Under different irrigations, the correlation between stem sap flow rate and total radiation was always the best.

  10. Comparative study of laminar and turbulent flow model with different operating parameters for radio frequency-inductively coupled plasma torch working at 3  MHz frequency at atmospheric pressure

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Punjabi, Sangeeta B., E-mail: p.sangeeta@gmail.com; Department of Physics, University of Mumbai, Kalina, Santacruz; Sahasrabudhe, S. N.

    2014-01-15

    This paper provides 2D comparative study of results obtained using laminar and turbulent flow model for RF (radio frequency) Inductively Coupled Plasma (ICP) torch. The study was done for the RF-ICP torch operating at 50 kW DC power and 3 MHz frequency located at BARC. The numerical modeling for this RF-ICP torch is done using ANSYS software with the developed User Defined Function. A comparative study is done between laminar and turbulent flow model to investigate how temperature and flow fields change when using different operating conditions such as (a) swirl and no swirl velocity for sheath gas flow rate, (b) variationmore » in sheath gas flow rate, and (c) variation in plasma gas flow rate. These studies will be useful for different material processing applications.« less

  11. Skeletal muscle contractions uncoupled from gravitational loading directly increase cortical bone blood flow rates in vivo.

    PubMed

    Caulkins, Carrie; Ebramzadeh, Edward; Winet, Howard

    2009-05-01

    The direct and indirect effects of muscle contraction on bone microcirculation and fluid flow are neither well documented nor explained. However, skeletal muscle contractions may affect the acquisition and maintenance of bone via stimulation of bone circulatory and interstitial fluid flow parameters. The purposes of this study were to assess the effects of transcutaneous electrical neuromuscular stimulation (TENS)-induced muscle contractions on cortical bone blood flow and bone mineral content, and to demonstrate that alterations in blood flow could occur independently of mechanical loading and systemic circulatory mechanisms. Bone chamber implants were used in a rabbit model to observe real-time blood flow rates and TENS-induced muscle contractions. Video recording of fluorescent microspheres injected into the blood circulation was used to calculate changes in cortical blood flow rates. TENS-induced repetitive muscle contractions uncoupled from mechanical loading instantaneously increased cortical microcirculatory flow, directly increased bone blood flow rates by 130%, and significantly increased bone mineral content over 7 weeks. Heart rates and blood pressure did not significantly increase due to TENS treatment. Our findings suggest that muscle contraction therapies have potential clinical applications for improving blood flow to cortical bone in the appendicular skeleton. Copyright 2008 Orthopaedic Research Society

  12. Fluid flow characteristics during polymer flooding

    NASA Astrophysics Data System (ADS)

    Yao, S. L.; Dou, H. E.; Wu, M.; Zhang, H. J.

    2018-05-01

    At present the main problems of polymer flooding is the high injection pressure which could not guarantee the later injection. In this paper the analyses of polymer’s physical properties and its solution’s variable movement characteristics in porous media reveal the inevitable trend of decrease in injection capacity and liquid production due to the increase of fluid viscosity and flow rate with more flow resistance. The injection rate makes the primary contribution to the active viscosity of the polymer solution in porous media. The higher injection rate, the greater shearing degradation and the more the viscosity loss. Besides the quantitative variation, the rate also changes qualitatively as that the injection rate demonstrates composite change of injection intensity and density. Due to the different adjustment function of the polymer solution on its injection profile, there should be different adjustment model of rates in such stages. Here in combination of the on-site recognitions, several conclusions and recommendations are made based on the study of the injection pattern adjustment during polymer flooding to improve the pressure distribution system, which would be a meaningful reference for extensive polymer flooding in the petroleum industry.

  13. Steep Gravel Bedload Rating Curves Obtained From Bedload Traps Shift Effective Discharge to Flows Much Higher Than "Bankfull"

    NASA Astrophysics Data System (ADS)

    Bunte, K.; Swingle, K. W.; Abt, S. R.; Cenderelli, D.

    2012-12-01

    Effective discharge (Qeff) is defined as the flow at which the product of flow frequency and bedload transport rates obtains its maximum. Qeff is often reported to correspond with bankfull flow (Qbf), where Qeff approximates the 1.5 year recurrence interval flow (Q1.5). Because it transports the majority of all bedload, Qeff is considered a design flow for stream restoration and flow management. This study investigates the relationship between Qeff and Q1.5 for gravel bedload in high elevation Rocky Mountain streams. Both the flow frequency distribution (FQ = a × Qbin-b) where Qbin is the flow class, and the bedload transport rating curve (QB = c × Qd) can be described by power functions. The product FQ × QB = (a × c × Q(-b + d)) is positive if d + -b >0, and negative if d + -b <0. FQ × QB can only attain a maximum (=Qeff) if either FQ or QB exhibit an inflection point. In snowmelt regimes, low flows prevail for much of the year, while high flows are limited to a few days, and extreme floods are rare. In log-log plotting scale, this distribution causes the longterm flow frequency function FQ to steepen in the vicinity of Q1.5. If the bedload rating curve exponent is small, e.g., = 3 as is typical of Helley-Smith bedload samples, d + -b shifts from >0 to <0, causing FQ × QB to peak, and Qeff to be around Q1.5. For measurements thought to be more representative of actual gravel transport obtained using bedload traps and similar devices, large rating curve exponents d of 6 - 16 are typical. In this case, d + -b remains >0, and FQ × QB reaches its maximum near the largest flow on record (Qeff,BT = Qmax). Expression of FQ by negative exponential functions FQ = k × e(Qbin×-m) smooths the product function FQ × QB that displays its maximum as a gentle hump rather than a sharp peak, but without drastically altering Qeff. However, a smooth function FQ × QB allows Qeff to react to small changes in rating curve exponents d. As d increases from <1 to >10, Qeff increases from Qmin to Qmax. The S-shaped relationship of Qeff vs. d shows that changes in d between about 4 and 8 exert the largest influence on Qeff. Not only FQ, but also QB may change its steepness. QB may flatten during floods as flows overtop banks. Many high elevation Rocky Mountain streams are entrenched due to floodplain buildup (overbank deposition and beaver activity) and downcutting. Preliminary flow modeling suggests that bank overtopping starts when Q1.5 >150%, and flows are fully out-of-bank past 200-250% Q1.5. A flattening of the bedload rating curve shifts Qeff from Qmax to within 150-250% Q1.5. Study results suggest that Qeff likely occurs within 150-250% Q1.5, and the often-quoted similarity of Qeff and Qbf (assuming Qbf = Q1.5) does not hold for the study streams, but is rather an artifact of using a Helley-Smith sampler that produces low rating curve exponents near 3. This finding calls into question the utility of Q1.5 or "bankfull flow" as a morphological design flow in high elevation Rocky Mountain streams.

  14. Electro-osmotically driven liquid delivery method and apparatus

    DOEpatents

    Rakestraw, D.J.; Anex, D.S.; Yan, C.; Dadoo, R.; Zare, R.N.

    1999-08-24

    Method and apparatus are disclosed for controlling precisely the composition and delivery of liquid at sub-{micro}L/min flow rate. One embodiment of such a delivery system is an electro-osmotically driven gradient flow delivery system that generates dynamic gradient flows with sub-{micro}L/min flow rates by merging a plurality of electro-osmotic flows. These flows are delivered by a plurality of delivery arms attached to a mixing connector, where they mix and then flow into a receiving means, preferably a column. Each inlet of the plurality of delivery arms is placed in a corresponding solution reservoir. A plurality of independent programmable high-voltage power supplies is used to apply a voltage program to each of the plurality of solution reservoirs to regulate the electro-osmotic flow in each delivery arm. The electro-osmotic flow rates in the delivery arms are changed with time according to each voltage program to deliver the required gradient profile to the column. 4 figs.

  15. Flow and evaporation in single micrometer and nanometer scale pipes

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Velasco, A. E.; Yang, C.; Siwy, Z. S.

    2014-07-21

    We report measurements of pressure driven flow of fluids entering vacuum through a single pipe of micrometer or nanometer scale diameter. Nanopores were fabricated by etching a single ion track in polymer or mica foils. A calibrated mass spectrometer was used to measure the flow rates of nitrogen and helium through pipes with diameter ranging from 10 μm to 31 nm. The flow of gaseous and liquid nitrogen was studied near 77 K, while the flow of helium was studied from the lambda point (2.18 K) to above the critical point (5.2 K). Flow rates were controlled by changing the pressure drop across the pipemore » in the range 0–31 atm. When the pressure in the pipe reached the saturated vapor pressure, an abrupt flow transition was observed. A simple viscous flow model is used to determine the position of the liquid/vapor interface in the pipe. The observed mass flow rates are consistent with no slip boundary conditions.« less

  16. The Progress in the Novel Pediatric Rotary Blood Pump Sputnik Development.

    PubMed

    Telyshev, Dmitry; Denisov, Maxim; Pugovkin, Alexander; Selishchev, Sergey; Nesterenko, Igor

    2018-04-01

    In this work, the study results of an implantable pediatric rotary blood pump (PRBP) are presented. They show the results of the numerical simulation of fluid flow rates in the pump. The determination method of the backflows and stagnation regions is represented. The operating points corresponding to fluid flow rates of 1, 3, and 5 L/min for 75-80 mm Hg pressure head are investigated. The study results have shown that use of the pump in the 1 L/min operating point can potentially lead to the appearance of backflows and stagnation regions. In the case of using pumps in fluid flow rates ranging from 3 to 5 L/min, the number of stagnation regions decreases and the fluid flow rate changes marginally. Using the pump in this flow rate range is considered judicious. The study shows an increase in shear stress with an increase in fluid flow rates, while there is no increase in shear stress above the critical condition of 150 Pa (which does not allow us to reliably speak about the increased risk of blood cell damage). The aim of this work was to design, prototype, and study interaction of the Sputnik PRBP with the cardiovascular system. A three-dimensional model of Sputnik PRBP was designed with the following geometrical specifications: flow unit length of 51.5 mm, flow unit diameter of 10 mm, and spacing between the rotor and housing of 0.1 mm. Computational fluid dynamics studies were used to calculate head pressure-flow rate (H-Q) curves at rotor speeds ranging from 10 000 to 14 000 rpm (R 2  = 0.866 between numerical simulation and experiment) and comparing flow patterns at various points of the flow rate operating range (1, 3, and 5 L/min) for operating pressures ranging from 75 to 80 mm Hg. It is noted that when fluid flow rate changes from 1 L/min to 3 L/min, significant changes are observed in the distribution of zero flow zones. At the inlet and outlet of the pump, when going to the operating point of 3 L/min, zones of stagnation become minuscule. The shear stress distribution was calculated along the pump volume. The volume in which shear stress exceed 150 Pa is less than 0.38% of the total pump volume at flow rates of 1, 3, and 5 L/min. In this study, a mock circulatory system (MCS) allowing simulation of physiological cardiovascular characteristics was used to investigate the interaction of the Sputnik PRBP with the cardiovascular system. MCS allows reproducing the Frank-Starling autoregulation mechanism of the heart. PRBP behavior was tested in the speed range of 6 000 to 15 000 rpm. Decreased contractility can be expressed in a stroke volume decrease approximately from 18 to 4 mL and ventricle systolic pressure decrease approximately from 92 to 20 mm Hg. The left ventricle becomes fully supported at a pump speed of 10 000 rpm. At a pump speed of 14 000 rpm, the left ventricle goes into a suction state in which fluid almost does not accumulate in the ventricle and only passes through it to the pump. The proposed PRBP showed potential for improved clinical outcomes in pediatric patients with a body surface area greater than 0.6 m 2 and weight greater than 12 kg. © 2018 International Center for Artificial Organs and Transplantation and Wiley Periodicals, Inc.

  17. Effects of variations in flow characteristics through W.P. Franklin Lock and Dam on downstream water quality in the Caloosahatchee River Estuary and in McIntyre Creek in the J.N. “Ding” Darling National Wildlife Refuge, southern Florida, 2010–13

    USGS Publications Warehouse

    Booth, Amanda C.; Soderqvist, Lars E.; Knight, Travis M.

    2016-05-17

    The U.S. Geological Survey studied water-quality trends at the mouth of McIntyre Creek, an entry point to the J.N. “Ding” Darling National Wildlife Refuge, to investigate correlations between flow rates and volumes through the W.P. Franklin Lock and Dam and water-quality constituents inside the refuge from March 2010 to December 2013. Outflow from Lake Okeechobee, and flows from Franklin Lock, tributaries to the Caloosahatchee River Estuary, and the Cape Coral canal system were examined to determine the sources and quantity of water to the study area. Salinity, temperature, dissolved-oxygen concentration, pH, turbidity, and chromophoric dissolved organic matter fluorescence (FDOM) were measured during moving-boat surveys and at a fixed location in McIntyre Creek. Chlorophyll fluorescence was also recorded in McIntyre Creek. Water-quality surveys were completed on 20 dates between 2011 and 2014 using moving-boat surveys.Franklin Lock contributed the majority of flow to the Caloosahatchee River. Between 2010 and 2013, the monthly mean flow rate at Franklin Lock ranged from 29 cubic feet per second in May 2011 to 10,650 cubic feet per second in August 2013. Instantaneous near-surface salinity in McIntyre Creek ranged from 12.9 parts per thousand on September 26, 2013, to 37.9 parts per thousand on June 27, 2011. Salinity in McIntyre Creek decreased with increasing flow rate through Franklin Lock. Flow rates through Franklin Lock explained 61 percent of the variation in salinity in McIntyre Creek. Salinity data from moving-boat surveys also indicate that an increase in flow rate at Franklin Lock decreases salinity in the Caloosahatchee River Estuary, and a reduction or elimination in flow increases salinity. The FDOM in McIntyre Creek was positively correlated with flow at Franklin Lock, and 54 percent of the variation in FDOM can be attributed to the flow rate through Franklin Lock. Data from moving-boat surveys indicate that FDOM increases when flow volume from Franklin Lock increases. The highest FDOM recorded during a survey was at Billy’s Creek. Chlorophyll fluorescence was positively correlated with flow at Franklin Lock, with 23 percent of the variation explained by the flow rate at Franklin Lock. An increase in flow rate at Franklin Lock resulted in a decrease in pH (21 percent of variation explained by flow rates). Data from the pH surveys indicate an increase in pH with distance from Franklin Lock. Turbidity and dissolved oxygen near the surface in McIntyre Creek were not correlated with flow rate at Franklin Lock. Moving-boat surveys did not document a change in turbidity or dissolved oxygen with a change in distance from the Franklin Lock. Correlations between Franklin Lock flow rate and water quality in McIntyre Creek indicate that releases at Franklin Lock affect water quality in the Caloosahatchee River Estuary and Ding Darling Refuge.

  18. Quantification aspects of constant pressure (ultra) high pressure liquid chromatography using mass-sensitive detectors with a nebulizing interface.

    PubMed

    Verstraeten, M; Broeckhoven, K; Lynen, F; Choikhet, K; Landt, K; Dittmann, M; Witt, K; Sandra, P; Desmet, G

    2013-01-25

    The present contribution investigates the quantitation aspects of mass-sensitive detectors with nebulizing interface (ESI-MSD, ELSD, CAD) in the constant pressure gradient elution mode. In this operation mode, the pressure is controlled and maintained at a set value and the liquid flow rate will vary according to the inverse mobile phase viscosity. As the pressure is continuously kept at the allowable maximum during the entire gradient run, the average liquid flow rate is higher compared to that in the conventional constant flow rate operation mode, thus shortening the analysis time. The following three mass-sensitive detectors were investigated: mass spectrometry detector (MS), evaporative light scattering detector (ELSD) and charged aerosol detector (CAD) and a wide variety of samples (phenones, polyaromatic hydrocarbons, wine, cocoa butter) has been considered. It was found that the nebulizing efficiency of the LC-interfaces of the three detectors under consideration changes with the increasing liquid flow rate. For the MS, the increasing flow rate leads to a lower peak area whereas for the ELSD the peak area increases compared to the constant flow rate mode. The peak area obtained with a CAD is rather insensitive to the liquid flow rate. The reproducibility of the peak area remains similar in both modes, although variation in system permeability compromises the 'long-term' reproducibility. This problem can however be overcome by running a flow rate program with an optimized flow rate and composition profile obtained from the constant pressure mode. In this case, the quantification remains reproducibile, despite any occuring variations of the system permeability. Furthermore, the same fragmentation pattern (MS) has been found in the constant pressure mode compared to the customary constant flow rate mode. Copyright © 2012 Elsevier B.V. All rights reserved.

  19. Extraction of long-chain fatty acids in isolated rat heart during acute low-flow ischemia.

    PubMed

    Richter, W S; Fischer, S; Ernst, N; Munz, D L

    2001-07-01

    Although beta-oxidation of fatty acids is suppressed rapidly during ischemia, the behavior of fatty acid extraction at different flow rates is incompletely understood. This study assessed the relationship between flow and extraction of (123)I-iodophenylpentadecanoic acid (IPPA) in the isolated heart model, especially at low flow. Isolated hearts from male Wistar rats (n = 15) were subjected to retrograde perfusion with constant flow (Krebs Henseleit solution containing 10 mmol/L glucose). A latex balloon in the left ventricle allowed isovolumetric contractions and ventricular pressure measurements. The extraction of (123)I-IPPA was assessed with the indicator dilution technique and (99m)Tc-albumin as the intravascular reference. The flow was either increased from the control flow (8 mL/min) until 300% or reduced until 10%. (123)I-IPPA extraction was measured three times before and 10 min after flow alteration. The tracer uptake was estimated from the product of net extraction and flow. The mean (123)I-IPPA extraction at the control flow (third measurement) was 51.6% +/- 2.8%. Between flow rates of approximately 25% and 300%, (123)I-IPPA extraction increased exponentially at decreasing flow rates. At flow rates < or =25% of the control flow, (123)I-IPPA extraction was exponentially higher than predicted. (123)I-IPPA uptake and flow changed largely in parallel. During low flow, the rate-pressure product showed the expected decline (perfusion-contraction matching). The extraction of (123)I-IPPA is preserved and slightly increased (relative to flow) during acute low-flow ischemia.

  20. Bone microvascular flow differs from skin microvascular flow in response to head-down tilt.

    PubMed

    Howden, Michelle; Siamwala, Jamila H; Hargens, Alan R

    2017-10-01

    Loss of hydrostatic pressures in microgravity may alter skin and bone microvascular flows in the lower extremities and potentially reduce wound healing and bone fracture repair. The purpose of this study was to determine the rate at which skin and bone microvascular flows respond to head-down tilt (HDT). We hypothesized that microvascular flows in tibial bone and overlying skin would increase at different rates during HDT. Tibial bone and skin microvascular flows were measured simultaneously using photoplethysmography (PPG) in a total of 17 subjects during sitting (control posture), supine, 6° HDT, 15° HDT, and 30° HDT postures in random order. With greater angles of HDT, bone microvascular flow increased significantly, but skin microvascular flow did not change. Tibial bone microvascular flow increased from the sitting control posture (0.77 ± 0.41 V) to supine (1.95 ± 1.01 V, P = 0.001) and from supine posture to 15° HDT (3.74 ± 2.43 V, P = 0.004) and 30° HDT (3.91 ± 2.68 V, P = 0.006). Skin microvascular flow increased from sitting (0.703 ± 0.75 V) to supine (2.19 ± 1.72 V, P = 0.02) but did not change from supine posture to HDT ( P = 1.0). We show for the first time that microcirculatory flows in skin and bone of the leg respond to simulated microgravity at different rates. These altered levels of blood perfusion may affect rates of wound and bone fracture healing in spaceflight. NEW & NOTEWORTHY Our data show that bone microvascular flow increases more than cutaneous blood flow with greater degrees of head-down tilt. A higher level of perfusion in bone may give insight into the bone mineral density loss in lower extremities of astronauts and why similar tissue degradation is not observed in the skin of the same areas. Copyright © 2017 the American Physiological Society.

  1. Gas-Liquid Flow in Pipelines

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Thomas J. Hanratty

    A research program was carried out at the University of Illinois in which develops a scientific approach to gas-liquid flows that explains their macroscopic behavior in terms of small scale interactions. For simplicity, fully-developed flows in horizontal and near-horizontal pipes. The difficulty in dealing with these flows is that the phases can assume a variety of configurations. The specific goal was to develop a scientific understanding of transitions from one flow regime to another and a quantitative understanding of how the phases distribute for a give regime. These basic understandings are used to predict macroscopic quantities of interest, such asmore » frictional pressure drop, liquid hold-up, entrainment in annular flow and frequency of slugging in slug flows. A number of scientific issues are addressed. Examples are the rate of atomization of a liquid film, the rate of deposition of drops, the behavior of particles in a turbulent field, the generation and growth of interfacial waves. The use of drag-reducing polymers that change macroscopic behavior by changing small scale interactions was explored.« less

  2. Using high-resolution satellite radar to measure lava flow morphology, rheology, effusion rate and subsidence at El Reventador Volcano, Ecuador.

    NASA Astrophysics Data System (ADS)

    Biggs, J.; Arnold, D. W. D.; Mothes, P. A.; Anderson, K. R.; Albino, F.; Wadge, G.; Vallejo Vargas, S.; Ebmeier, S. K.

    2017-12-01

    There are relatively few studies of active lava flows of an andesitic rather than basaltic composition. The flow field at El Reventador volcano, Ecuador is a good example, but observations are hampered by persistent cloud cover. We use high resolution satellite radar from Radarsat-2 and TanDEM-X to map the dimensions of 43 lava flows extruded between 9 Feb 2012 and 24 Aug 2016. Flow height is measured using the width of radar shadow cast by steep sided features, or the difference in radar phase between two sensors separated in space. The cumulative volume of erupted material was 44.8M m3 dense rock equivalent with an average rate of 0.31 ± 0.02 m3s-1, similar to the long term average. The flows were mostly emplaced over durations shorter than the satellite repeat interval of 24 days and ranged in length from 0.3 to 1.7 km. We use the dimensions of the levees to estimate the flow yield strengths and compare measurements of diversions around barriers with observations from laboratory experiments. The rate of effusion, flow length and flow volume all decrease with time, and simple physics-based models can be equally well fit by a closed reservoir depressurising during the eruption with no magma recharge, or an open reservoir with a time-constant magma recharge rate of up to 0.35 ± 0.01 m3s-1. We propose that the conduit acts as magma capacitor and individual flows are volume-limited. Emplaced flows are subsiding at rates proportional to lava thickness that decay with time following a square-root relationship. Radar observations, such as those presented here, could be used to map and measure properties of evolving lava flow fields at other remote or difficult to monitor volcanoes. Physics-based models can be run into the future, but a sudden increase in flow length in 2017 seen by Sentinel illustrates that changes in magma supply can cause rapid changes in behavior, which remain challenging to forecast.

  3. Observation of the L-H confinement bifurcation triggered by a turbulence-driven shear flow in a tokamak plasma.

    PubMed

    Yan, Z; McKee, G R; Fonck, R; Gohil, P; Groebner, R J; Osborne, T H

    2014-03-28

    Comprehensive 2D turbulence and eddy flow velocity measurements on DIII-D demonstrate a rapidly increasing turbulence-driven shear flow that develops ∼100  μs prior to the low-confinement (L mode) to high-confinement (H mode) transition and appears to trigger it. These changes are localized to a narrow layer 1-2 cm inside the magnetic boundary. Increasing heating power increases the Reynolds stress, the energy transfer from turbulence to the poloidal flow, and the edge flow shearing rate that then exceeds the decorrelation rate, suppressing turbulence and triggering the transition.

  4. Vasopressin-induced changes in splanchnic blood flow and hepatic and portal venous pressures in liver resection.

    PubMed

    Bown, L Sand; Ricksten, S-E; Houltz, E; Einarsson, H; Söndergaard, S; Rizell, M; Lundin, S

    2016-05-01

    To minimize blood loss during hepatic surgery, various methods are used to reduce pressure and flow within the hepato-splanchnic circulation. In this study, the effect of low- to moderate doses of vasopressin, a potent splanchnic vasoconstrictor, on changes in portal and hepatic venous pressures and splanchnic and hepato-splanchnic blood flows were assessed in elective liver resection surgery. Twelve patients were studied. Cardiac output (CO), stroke volume (SV), mean arterial (MAP), central venous (CVP), portal venous (PVP) and hepatic venous pressures (HVP) were measured, intraoperatively, at baseline and during vasopressin infusion at two infusion rates (2.4 and 4.8 U/h). From arterial and venous blood gases, the portal (splanchnic) and hepato-splanchnic blood flow changes were calculated, using Fick's equation. CO, SV, MAP and CVP increased slightly, but significantly, while systemic vascular resistance and heart rate remained unchanged at the highest infusion rate of vasopressin. PVP was not affected by vasopressin, while HVP increased slightly. Vasopressin infusion at 2.4 and 4.8 U/h reduced portal blood flow (-26% and -37%, respectively) and to a lesser extent hepato-splanchnic blood flow (-9% and -14%, respectively). The arterial-portal vein lactate gradient was not significantly affected by vasopressin. Postoperative serum creatinine was not affected by vasopressin. Short-term low to moderate infusion rates of vasopressin induced a splanchnic vasoconstriction without metabolic signs of splanchnic hypoperfusion or subsequent renal impairment. Vasopressin caused a centralization of blood volume and increased cardiac output. Vasopressin does not lower portal or hepatic venous pressures in this clinical setting. © 2016 The Acta Anaesthesiologica Scandinavica Foundation. Published by John Wiley & Sons Ltd.

  5. The role of varying flow on channel morphology: a flume experiment

    NASA Astrophysics Data System (ADS)

    Hempel, L. A.; Grant, G.; Eaton, B. C.; Hassan, M. A.; Lewis, S.

    2017-12-01

    Numerous studies have explored how alluvial channels develop under different sediment and flow conditions, yet we still know very little about how channels adjust and respond to changing flow conditions. One reason for this oversight is the long-held idea that channels with complex flow regimes are adjusted to a single, channel-forming discharge. But growing evidence shows that channel form reflects time-dependent processes occuring over multiple flows. To better understand how stream channels adjust to a range of flows, and identify the timescales associated with those adjustments, we conducted a series of hydrograph experiments in a freely-adjustable flume that developed a self-formed, meander pattern with pool-riffle morphology. Hydrographs had different shapes, magnitudes, and durations, but the total sediment volume fed under equilibrium conditions was kept constant among experiments. We found that hydrograph shape controlled channel morphology, the rate of channel development, and degree of regularity in the pool-riffle pattern. Hydrographs with slowly rising rates of rise and fall produced channels that were equivalent in size to channels generated from constant flow experiments, and had regularly spaced pool-riffle and meander patterns, while hydrographs with fast rates of rise and fall produced undersized channels with a chaotic bed structure and pool-riffle pattern. The latter suggests that during quickly rising hydrographs, the flow rate increases faster than the channel capacity and planform pattern adjusts. We confirmed these observations by comparing the timescales associated with pool-riffle and planform curvature development, which were identified under simple, constant flow conditions, to the total duration of the hydrograph. Hydrographs with step durations equal to or longer than the channel adjustment time produced channels with a more regular pool-riffle patterns compared to channels with step durations shorter than the adjustment time. This work points to the importance of the hydrograph as a fundamental control on channel adjustment and offers the prospect of better understanding of how changes in the flow regime, either through climate, land use, or dams, translate into morphodynamic changes.

  6. Seven-Day Low Streamflows in the United States, 1940-2014

    EPA Pesticide Factsheets

    This map shows percentage changes in the minimum annual rate of water carried by rivers and streams across the country, based on the long-term rate of change from 1940 to 2014. Minimum streamflow is based on the consecutive seven-day period with the lowest average flow during a given year. Blue triangles represent an increase in low stream flow volumes, and brown triangles represent a decrease. Streamflow data were collected by the U.S. Geological Survey. For more information: www.epa.gov/climatechange/science/indicators

  7. Analysis of antigen-induced changes in pulmonary mechanics in sensitized inbred rats.

    PubMed

    Holroyde, M C; Smith, S Y; Holme, G

    1982-05-01

    An inbred line of rats was derived which develop marked and consistent dyspnea following sensitization and then exposure to aerosolized antigen. This pulmonary response was investigated in detail by determining forced pulmonary mechanics to derive respiratory rate, peak expiratory flow rate (PEFR), forced vital capacity (FVC), forced expiratory volume in 0.1 s (FEV0.1), and maximal midexpiratory flow rate (MMFR). Challenging anesthetized rats for 5 min with an aerosol of 3% egg albumin produced minimal change in respiratory rate, a 20% fall in PEFR, a 50% fall in FVC, and a 30% decrease in FEV0.1 and MMFR. The response could be inhibited or reversed by salbutamol (0.5 mg/kg, i.v.) and aminophylline (25 mg/kg, i.v.) administered either before or after challenge. The pulmonary changes are consistent with antigen-induced asthma in the rats. The response shows similarities to human asthma and may provide a relevant experimental model.

  8. Erosion of water-based fracturing fluid containing particles in a sudden contraction of horizontal pipe

    NASA Astrophysics Data System (ADS)

    Cheng, Jiarui; Cao, Yinping; Dou, Yihua; Li, Zhen

    2017-10-01

    A lab experiment was carried out to study the effects of pipe flow rate, particle concentration and pipe inner diameter ratio on proppant erosion of the reducing wall in hydraulic fracturing. The results show that the erosion rate and erosion distribution are different not only in radial direction but also in circumferential direction of the sample. The upper part of sample always has a minimum erosion rate and erosion area. Besides, the erosion rate of reducing wall is most affected by fluid flow velocity, and the erosion area is most sensitive to the change in the diameter ratio. Meanwhile, the erosion rate of reducing wall in crosslinked fracturing fluid is mainly determined by the fluid flowing state due to the high viscosity of the liquid. In general, the increase in flow velocity and diameter ratio not only cause the expansion of erosion-affected flow region in sudden contraction section, but also lead to more particles impact the wall.

  9. Simulation of the effects of ground-water withdrawals and recharge on ground-water flow in Cape Cod, Martha's Vineyard, and Nantucket Island basins, Massachusetts

    USGS Publications Warehouse

    Masterson, John P.; Barlow, Paul M.

    1994-01-01

    The effects of changing patterns of ground-water pumping and aquifer recharge on the surface-water and ground-water hydrologic systems were determined for the Cape Cod, Martha's Vineyard, and Nantucket Island Basins. Three-dimensional, transient, ground-water-flow modelS that simulate both freshwater and saltwater flow were developed for the f1ow cells of Cape Cod which currently have large-capacity public-supply wells. Only the freshwater-flow system was simulated for the Cape Cod flow cells where public-water supply demands are satisfied by small-capacity domestic wells. Two- dimensional, finite-difference, change models were developed for Martha's Vineyard and Nantucket Island to determine the projected drawdowns in response to projected in-season pumping rates for 180 days of no aquifer recharge. Results of the simulations indicate very little change in the position of the freshwater-saltwater interface from predevelopment flow conditions to projected ground-water pumping and recharge rates for Cape Cod in the year 2020. Results of change model simulations for Martha's Vineyard and Nantucket Island indicate that the greatest impact in response to projected in-season ground-water pumping occurs at the pumping centers and the magnitude of the drawdowns are minimal with respect to the total thickness of the aquifers.

  10. Decomposing the effect of crime on population changes.

    PubMed

    Foote, Andrew

    2015-04-01

    This article estimates the effect of crime on migration rates for counties in U.S. metropolitan areas and makes three contributions to the literature. First, I use administrative data on migration flows between counties, which gives me more precise estimates of population changes than data used in previous studies. Second, I am able to decompose net population changes into gross migration flows in order to identify how individuals respond to crime rate changes. Finally, I include county-level trends so that my identification comes from shocks away from the trend. I find effects that are one-fiftieth the size of the most prominent estimate in the literature; and although the long-run effects are somewhat larger, they are still only approximately one-twentieth as large. I also find that responses to crime rates differ by subgroups, and that increases in crime cause white households to leave the county, with effects almost 10 times as large as for black households.

  11. Geochemistry of manganese, iron, uranium, lead-210 and major ions in the Susquehanna River

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lewis, D.M.

    1976-01-01

    The change in water composition accompanying a change in discharge of large streams and the Susquehanna River results from the change in the proportions of the total flow composed of type waters of constant composition. This change in the flow proportions is due to the different hydrologic responses to precipitation inputs of basins underlain by different single rock types. The in-river precipitation of mine-drainage-injected Mn and Fe was studied at a pH of approximately 7. For Mn the removal from solution appears to be first order. The rate constant is 10/sup 3/ times greater than the extrapolated autocatalytic rate constantmore » of previous laboratory experiments. The study of the removal of Fe from solution yields a first order rate constant consistent with previous laboratory experiments. Lead-210 was used as a natural tracer to study the fate of trace metals.« less

  12. Fluid Mechanics of Wing Adaptation for Separation Control

    NASA Technical Reports Server (NTRS)

    Chandrasekhara, M. S.; Wilder, M. C.; Carr, L. W.; Davis, Sanford S. (Technical Monitor)

    1997-01-01

    The unsteady fluid mechanics associated with use of a dynamically deforming leading edge airfoil for achieving compressible flow separation control has been experimentally studied. Changing the leading edge curvature at rapid rates dramatically alters the flow vorticity dynamics which is responsible for the many effects observed in the flow.

  13. Separation Dynamics of Controlled Internal Flow in an Adverse Pressure Gradient

    NASA Astrophysics Data System (ADS)

    Peterson, C. J.; Vukasinovic, B.; Glezer, A.

    2017-11-01

    The effects of fluidic actuation on the dynamic evolution of aggressive internal flow separation is investigated at speeds up to M = 0.4 within a constant-width diffuser branching off of a primary flow duct. It is shown that a spanwise array of fluidic actuators upstream of the separation actively controls the flow constriction (and losses) within the diffuser and consequently the local pressure gradient at its entrance. The effectiveness of the actuation, as may be measured by the increased flow rate that is diverted through the diffuser, scales with its flow rate coefficient. In the presence of actuation (0.7% mass fraction), the mass flow rate in the primary duct increases by 10% while the fraction of the diverted mass flow rate in the diffuser increases by more than 45%. The flow dynamics near separation in the absence and presence of actuation are characterized using high speed particle image velocimetry and analyzed using proper orthogonal and spectral decompositions. In particular, the spectral contents of the incipient boundary layer separation are compared in the absence and presence of actuation with emphasis on the changes in local dynamics near separation as the characteristic cross stream scale of the boundary layer increases with separation delay.

  14. Progress in fuel systems to meet new fuel economy and emissions standards

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    1995-12-31

    This publication includes information describing the latest developments within the automotive industry on fuel system hardware and control strategies. Contents include: Slow heating process of a heated pintle-type gasoline fuel injector; Mixture preparation measurements; Study of fuel flow rate change in injector for methanol fueled S.I. engine; Flow and structural analysis for fuel pressure regulator performance; A new method to analyze fuel behavior in a spark ignition engine; Throttle body at engine idle -- tolerance effect on flow rate; and more.

  15. Cerebral blood velocity and other cardiovascular responses to 2 days of head-down tilt

    NASA Technical Reports Server (NTRS)

    Frey, Mary A. B.; Mader, Thomas H.; Bagian, James P.; Charles, John B.; Meehan, Richard T.

    1993-01-01

    Spaceflight induces a cephalad redistribution of fluid volume and blood flow within the human body, and space motion sickness, which is a problem during the first few days of space flight, could be related to these changes in fluid status and in blood flow of the cerebrum and vestibular system. To evaluate possible changes in cerebral blood flow during simulated weightlessness, we measured blood velocity in the middle cerebral artery (MCA) along with retinal vascular diameters, intraocular pressure, impedance cardiography, and sphygmomanometry on nine men (26.2 +/- 6.6 yr) morning and evening for 2 days during continuous 10 deg head-down tilt (HDT). When subjects went from seated to head-down bed rest, their heart rate and retinal diameters decreased, and intraocular pressures increased. After 48 h of HDT, blood flow velocity in the MCA was decreased and thoracic impedance was increased, indicating less fluid in the thorax. Percent changes in blood flow velocities in the MCA after 48 h of HDT were inversely correlated with percent changes in retinal vascular diameters. Blood flow velocities in the MCA were inversely correlated (intersubject) with arterial pressures and retinal vascular diameters. Heart rate, stroke volume, cardiac output, systolic arterial pressure, and at times pulse pressure and blood flow velocities in the MCA were greater in the evening. Total peripheral resistance was higher in the morning. Although cerebral blood velocity is reduced after subjects are head down for 2 days, the inverse relationship with retinal vessel diameters, which have control analogous to that of cerebral vessels, indicates cerebral blood flow is not reduced.

  16. Recent Advances in Synthesis and Characterization of SWCNTs Produced by Laser Oven Process

    NASA Technical Reports Server (NTRS)

    Aepalli, Sivaram

    2004-01-01

    Results from the parametric study of the two-laser oven process indicated possible improvements with flow conditions and laser characteristics. Higher flow rates, lower operating pressures coupled with changes in flow tube material are found to improve the nanotube yields. The collected nanotube material is analyzed using a combination of characterization techniques including SEM, TEM, TGA, Raman and UV-VIS-NIR to estimate the purity of the samples. In-situ diagnostics of the laser oven process is now extended to include the surface temperature of the target material. Spectral emission from the target surface is compared with black body type emission to estimate the temperature. The surface temperature seemed to correlate well with the ablation rate as well as the quality of the SWCNTs. Recent changes in improving the production rate by rastering the target and using cw laser will be presented.

  17. Recent Advances in Synthesis and Characterization of SWCNTs produced by laser oven process

    NASA Technical Reports Server (NTRS)

    Arepalli, Sivaram

    2004-01-01

    Results from the parametric study of the two-laser oven process indicated possible improvements with flow conditions and laser characteristics (ref. 1). Higher flow rates, lower operating pressures coupled with changes in flow tube material are found to improve the nanotube yields. The collected nanotube material is analyzed using a combination of characterization techniques including SEM, TEM, TGA, Raman and UV-VIS-NIR to estimate the purity of the samples. Insitu diagnostics of the laser oven process is now extended to include the surface temperature of the target material. Spectral emission from the target surface is compared with black body type emission to estimate the temperature. The surface temperature seemed to correlate well with the ablation rate as well as the quality of the SWCNTs. Recent changes in improving the production rate by rastering the target and using cw laser will be presented.

  18. Flow experience and the mobilization of attentional resources.

    PubMed

    de Sampaio Barros, Marcelo Felipe; Araújo-Moreira, Fernando M; Trevelin, Luis Carlos; Radel, Rémi

    2018-05-07

    The present study attempts to better identify the neurophysiological changes occurring during flow experience and how this can be related to the mobilization of attentional resources. Self-reports of flow (using a flow feelings scale) and attention (using thought probes), autonomic activity (heart rate, heart rate variability, and breathing rate), and cerebral oxygenation (using near-infrared spectroscopy) in two regions of the frontoparietal attention network (right lateral frontal cortex and right inferior parietal lobe) were measured during the practice of two simple video games (Tetris and Pong) played at different difficulty conditions (easy, optimal, hard, or self-selected). Our results indicated that an optimal level of difficulty, compared with an easy or hard level of difficulty led to greater flow feelings and a higher concentration of oxygenated hemoglobin in the regions of the frontoparietal network. The self-selected, named autonomy condition did not lead to more flow feelings than the optimal condition; however, the autonomy condition led to greater sympathetic activity (reduced heart rate variability and greater breathing rate) and higher activation of the frontoparietal regions. Our study suggests that flow feelings are highly connected to the mobilization of attentional resources, and all the more in a condition that promotes individuals' choice and autonomy.

  19. Space Vehicle Valve System

    NASA Technical Reports Server (NTRS)

    Kelley, Anthony R. (Inventor); Lindner, Jeffrey L. (Inventor)

    2014-01-01

    The present invention is a space vehicle valve system which controls the internal pressure of a space vehicle and the flow rate of purged gases at a given internal pressure and aperture site. A plurality of quasi-unique variable dimension peaked valve structures cover the purge apertures on a space vehicle. Interchangeable sheet guards configured to cover valve apertures on the peaked valve structure contain a pressure-activated surface on the inner surface. Sheet guards move outwardly from the peaked valve structure when in structural contact with a purge gas stream flowing through the apertures on the space vehicle. Changing the properties of the sheet guards changes the response of the sheet guards at a given internal pressure, providing control of the flow rate at a given aperture site.

  20. The subtype of alpha-adrenoceptor involved in the neural control of renal tubular sodium reabsorption in the rabbit.

    PubMed Central

    Hesse, I F; Johns, E J

    1984-01-01

    A study was undertaken in pentobarbitone anaesthetized rabbits, undergoing a saline diuresis, to determine the subtype of alpha-adrenoceptor mediating renal tubular sodium reabsorption. Stimulation of the renal nerves at low rates, to cause an 11% fall in renal blood flow, did not change glomerular filtration rate but significantly reduced urine flow rate, and absolute and fractional sodium excretions by approximately 40%. These responses were reproducible in different groups of animals and with time. Renal nerve stimulation during an intra-renal arterial infusion of prazosin, to block alpha 1-adrenoceptors, had no effect on the renal haemodynamic response but completely abolished the reductions in urine flow rate, and absolute and fractional sodium excretion. During intra-renal arterial infusion of yohimbine, to block renal alpha 2-adrenoceptors, stimulation of the renal nerves to cause similar renal haemodynamic changes resulted in significantly larger reductions in urine flow rate, and absolute and fractional sodium excretion of about 52-58%. These results indicate that in the rabbit alpha 1-adrenoceptors are present on the renal tubules, which mediate the increase in sodium reabsorption caused by renal nerve stimulation. They further suggest the presence of presynaptic alpha 2-adrenoceptors on those nerves innervating the renal tubules. PMID:6086915

  1. Mixing efficiency inside micro-droplets coalesced by two components in cross-structure

    NASA Astrophysics Data System (ADS)

    Ren, Yanlin; Liu, Zhaomiao; Pang, Yan

    2017-11-01

    The mixing of micro-droplets is used in analytical chemistry, medicine production and material synthesis owing to its advantages including the encapsulation and narrow time residence distribution. In this work, droplets are coalesced by two dispersed phase with different flow rates, generated in cross-structure and mixed in planar serpentine structure. The mixing efficiency of micro-droplets under control characters including the width of entrance and the flow rate of dispersed phases have been investigated by experiments and numerical simulations. The UDS (user-defined scalar) as dimensionless concentration of the solution is adopted in simulation, and is used to calculate the concentration and the mixing effect. By changing the flow rates and the entrances` width, the changing rules of the mixing characters have been obtained. The asymmetry distributions of components make rapid mixing process in half part of each droplet when travel through a straight channel. Increasing of the ratio of entrance width result into larger droplet and weaken the chaotic mixing effect. Meanwhile, the coalesced mechanism can be performed by ranging the ratio of flow rates, the ranges are also determined by the widths of entrances. The authors gratefully acknowledge the support of National Natural Science Foundation of China (Grant No. 11572013).

  2. Final Report for research on The Glucose 6-Phosphate Shunt Around the Calvin-Benson Cycle

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sharkey, Thomas D.

    In this research, photosynthetic carbon metabolism was studied to identify mechanisms by which plants store energy from sunlight as carbon compounds, especially sugars. Conditions were identified in which carbon appeared to flow backwards from outside the photosynthetic compartment (chloroplast) back into it. A specific gene product was manipulated to make the flow bigger or smaller. Preventing the flow (by eliminating the gene) had little effect on plant growth but increasing the flow, by overexpressing the gene, caused the plants to become extremely sensitive to changes in light. Plants with the gene overexpressed had high rates of cyclic electron flow, themore » photosynthetic electron transport pathway that occurs when plants need more of the energy molecule ATP. These and other observations led us to conclude that a metabolic pathway that is normally turned off because it is counter-productive during photosynthesis, in fact occurs at about 10% of the rate of normal photosynthesis. This creates an inefficiency but may stabilize photosynthesis allowing it to cope with the very large and rapid changes that leaves experience such as the hundred-fold changes in light intensity that can occur in seconds on a partly cloudy day. We also concluded that the back flow of carbon into chloroplasts could be important at high rates of photosynthesis allowing increased rates of starch synthesis. Starch synthesis allows plants to store sugars during the day for use at night. At high rates of photosynthesis starch synthesis becomes very important to protect against end-product inhibition of photosynthesis. This research identified two metabolic pathways that extend the primary carbon fixation pathway called the Calvin-Benson cycle. These pathway extensions are now called the cytosolic bypass and the glucose 6-phosphate shunt. This improvement in our understanding of carbon metabolism of photosynthesis will guide efforts to increase photosynthesis to increase production of food, fuel, and fiber.« less

  3. Air-flow regulation system for a coal gasifier

    DOEpatents

    Fasching, George E.

    1984-01-01

    An improved air-flow regulator for a fixed-bed coal gasifier is provided which allows close air-flow regulation from a compressor source even though the pressure variations are too rapid for a single primary control loop to respond. The improved system includes a primary controller to control a valve in the main (large) air supply line to regulate large slow changes in flow. A secondary controller is used to control a smaller, faster acting valve in a secondary (small) air supply line parallel to the main line valve to regulate rapid cyclic deviations in air flow. A low-pass filter with a time constant of from 20 to 50 seconds couples the output of the secondary controller to the input of the primary controller so that the primary controller only responds to slow changes in the air-flow rate, the faster, cyclic deviations in flow rate sensed and corrected by the secondary controller loop do not reach the primary controller due to the high frequency rejection provided by the filter. This control arrangement provides at least a factor of 5 improvement in air-flow regulation for a coal gasifier in which air is supplied by a reciprocating compressor through a surge tank.

  4. Development and Characterization a Single-Active-Chamber Piezoelectric Membrane Pump with Multiple Passive Check Valves.

    PubMed

    Zhang, Ronghui; You, Feng; Lv, Zhihan; He, Zhaocheng; Wang, Haiwei; Huang, Ling

    2016-12-12

    In order to prevent the backward flow of piezoelectric pumps, this paper presents a single-active-chamber piezoelectric membrane pump with multiple passive check valves. Under the condition of a fixed total number of passive check valves, by means of changing the inlet valves and outlet valves' configuration, the pumping characteristics in terms of flow rate and backpressure are experimentally investigated. Like the maximum flow rate and backpressure, the testing results show that the optimal frequencies are significantly affected by changes in the number inlet valves and outlet valves. The variation ratios of the maximum flow rate and the maximum backpressure are up to 66% and less than 20%, respectively. Furthermore, the piezoelectric pump generally demonstrates very similar flow rate and backpressure characteristics when the number of inlet valves in one kind of configuration is the same as that of outlet valves in another configuration. The comparison indicates that the backflow from the pumping chamber to inlet is basically the same as the backflow from the outlet to the pumping chamber. No matter whether the number of inlet valves or the number of outlet valves is increased, the backflow can be effectively reduced. In addition, the backpressure fluctuation can be significantly suppressed with an increase of either inlet valves or outlet valves. It also means that the pump can prevent the backflow more effectively at the cost of power consumption. The pump is very suitable for conditions where more accurate flow rates are needed and wear and fatigue of check valves often occur.

  5. On the wind production from hot accretion flows with different accretion rates

    NASA Astrophysics Data System (ADS)

    Bu, De-Fu; Gan, Zhao-Ming

    2018-02-01

    We perform two-dimensional simulations to study how the wind strength changes with accretion rate. We take into account bremsstrahlung, synchrotron radiation and the Comptonization. We find that when the accretion rate is low, radiative cooling is not important, and the accretion flow is hot. For the hot accretion flow, wind is very strong. The mass flux of wind can be ˜ 50 per cent of the mass inflow rate. When the accretion rate increases to a value at which radiative cooling rate is roughly equal to or slightly larger than viscous heating rate, cold clumps can form around the equatorial plane. In this case, the gas pressure gradient force is small and wind is very weak. Our results may be useful for the sub-grid model of active galactic nuclear feedback study.

  6. Spiral blood flow in aorta-renal bifurcation models.

    PubMed

    Javadzadegan, Ashkan; Simmons, Anne; Barber, Tracie

    2016-01-01

    The presence of a spiral arterial blood flow pattern in humans has been widely accepted. It is believed that this spiral component of the blood flow alters arterial haemodynamics in both positive and negative ways. The purpose of this study was to determine the effect of spiral flow on haemodynamic changes in aorta-renal bifurcations. In this regard, a computational fluid dynamics analysis of pulsatile blood flow was performed in two idealised models of aorta-renal bifurcations with and without flow diverter. The results show that the spirality effect causes a substantial variation in blood velocity distribution, while causing only slight changes in fluid shear stress patterns. The dominant observed effect of spiral flow is on turbulent kinetic energy and flow recirculation zones. As spiral flow intensity increases, the rate of turbulent kinetic energy production decreases, reducing the region of potential damage to red blood cells and endothelial cells. Furthermore, the recirculation zones which form on the cranial sides of the aorta and renal artery shrink in size in the presence of spirality effect; this may lower the rate of atherosclerosis development and progression in the aorta-renal bifurcation. These results indicate that the spiral nature of blood flow has atheroprotective effects in renal arteries and should be taken into consideration in analyses of the aorta and renal arteries.

  7. Anatomic and physiologic changes of the aging kidney.

    PubMed

    Karam, Zeina; Tuazon, Jennifer

    2013-08-01

    Aging is associated with structural and functional changes in the kidney. Structural changes include glomerulosclerosis, thickening of the basement membrane, increase in mesangial matrix, tubulointerstitial fibrosis and arteriosclerosis. Glomerular filtration rate is maintained until the fourth decade of life, after which it declines. Parallel reductions in renal blood flow occur with redistribution of blood flow from the cortex to the medulla. Other functional changes include an increase in glomerular basement permeability and decreased ability to dilute or concentrate urine. Copyright © 2013 Elsevier Inc. All rights reserved.

  8. Criteria for choosing an intravenous infusion line intended for multidrug infusion in anaesthesia and intensive care units.

    PubMed

    Maiguy-Foinard, Aurélie; Genay, Stéphanie; Lannoy, Damien; Barthélémy, Christine; Lebuffe, Gilles; Debaene, Bertrand; Odou, Pascal; Décaudin, Bertrand

    2017-02-01

    The aims are to identify critical parameters influencing the drug mass flow rate of infusion delivery to patients during multidrug infusion and to discuss their clinical relevance. A review of literature was conducted in January 2016 using Medline, Google Scholar, ScienceDirect, Web of Science and Scopus online databases. References relating to the accuracy of fluid delivery via gravity-flow intravenous (IV) infusion systems and positive displacement pumps, components of IV administration sets, causes of flow rate variability, potential complications due to flow rate variability, IV therapies especially at low flow rates and drug compatibilities were considered relevant. Several parameters impact the delivery of drugs and fluids by IV infusion. Among them are the components of infusion systems that particularly influence the flow rate of medications and fluids being delivered. By their conception, they may generate significant start-up delays and flow rate variability. Performing multidrug infusion requires taking into account two main points: the common dead volume of drugs delivered simultaneously with potential consequences on the accuracy and amount of drug delivery and the prevention of drug incompatibilities and their clinical effects. To prevent the potentially serious effects of flow rate variability on patients, clinicians should receive instruction on the fluid dynamics of an IV administration set and so be able to take steps to minimise flow rate changes during IV therapy. Copyright © 2016 Société française d’anesthésie et de réanimation (Sfar). Published by Elsevier Masson SAS. All rights reserved.

  9. Effect of the carrier gas flow rate on the microstructure evolution and the generation of the charged nanoparticles during silicon chemical vapor deposition.

    PubMed

    Youn, Woong-Kyu; Kim, Chan-Soo; Hwang, Nong-Moon

    2013-10-01

    The generation of charged nanoparticles in the gas phase has been continually reported in many chemical vapor deposition processes. Charged silicon nanoparticles in the gas phase were measured using a differential mobility analyzer connected to an atmospheric-pressure chemical vapor deposition reactor at various nitrogen carrier gas flow rates (300-1000 standard cubic centimeter per minute) under typical conditions for silicon deposition at the reactor temperature of 900 degrees C. The carrier gas flow rate affected not only the growth behavior of nanostructures but also the number concentration and size distribution of both negatively and positively charged nanoparticles. As the carrier gas flow rate decreased, the growth behavior changed from films to nanowires, which grew without catalytic metal nanoparticles on a quartz substrate.

  10. Understanding which parameters control shallow ascent of silicic effusive magma

    NASA Astrophysics Data System (ADS)

    Thomas, Mark E.; Neuberg, Jurgen W.

    2014-11-01

    The estimation of the magma ascent rate is key to predicting volcanic activity and relies on the understanding of how strongly the ascent rate is controlled by different magmatic parameters. Linking potential changes of such parameters to monitoring data is an essential step to be able to use these data as a predictive tool. We present the results of a suite of conduit flow models Soufrière that assess the influence of individual model parameters such as the magmatic water content, temperature or bulk magma composition on the magma flow in the conduit during an extrusive dome eruption. By systematically varying these parameters we assess their relative importance to changes in ascent rate. We show that variability in the rate of low frequency seismicity, assumed to correlate directly with the rate of magma movement, can be used as an indicator for changes in ascent rate and, therefore, eruptive activity. The results indicate that conduit diameter and excess pressure in the magma chamber are amongst the dominant controlling variables, but the single most important parameter is the volatile content (assumed as only water). Modeling this parameter in the range of reported values causes changes in the calculated ascent velocities of up to 800%.

  11. Evaluating the Controls on Magma Ascent Rates Through Numerical Modelling

    NASA Astrophysics Data System (ADS)

    Thomas, M. E.; Neuberg, J. W.

    2015-12-01

    The estimation of the magma ascent rate is a key factor in predicting styles of volcanic activity and relies on the understanding of how strongly the ascent rate is controlled by different magmatic parameters. The ability to link potential changes in such parameters to monitoring data is an essential step to be able to use these data as a predictive tool. We present the results of a suite of conduit flow models that assess the influence of individual model parameters such as the magmatic water content, temperature or bulk magma composition on the magma flow in the conduit during an extrusive dome eruption. By systematically varying these parameters we assess their relative importance to changes in ascent rate. The results indicate that potential changes to conduit geometry and excess pressure in the magma chamber are amongst the dominant controlling variables that effect ascent rate, but the single most important parameter is the volatile content (assumed in this case as only water). Modelling this parameter across a range of reported values causes changes in the calculated ascent velocities of up to 800%, triggering fluctuations in ascent rates that span the potential threshold between effusive and explosive eruptions.

  12. Electric-field-induced flow-aligning state in a nematic liquid crystal.

    PubMed

    Fatriansyah, Jaka Fajar; Orihara, Hiroshi

    2015-04-01

    The response of shear stress to a weak ac electric field as a probe is measured in a nematic liquid crystal under shear flow and dc electric fields. Two states with different responses are clearly observed when the dc electric field is changed at a constant shear rate: the flow aligning and non-flow aligning states. The director lies in the shear plane in the flow aligning state and out of the plane in the non-flow aligning state. Through application of dc electric field, the non-flow aligning state can be changed to the flow aligning state. In the transition from the flow aligning state to the non-flow aligning state, it is found that the response increases and the relaxation time becomes longer. Here, the experimental results in the flow aligning state are discussed on the basis of the Ericksen-Leslie theory.

  13. Elements of an improved model of debris‐flow motion

    USGS Publications Warehouse

    Iverson, Richard M.

    2009-01-01

    A new depth‐averaged model of debris‐flow motion describes simultaneous evolution of flow velocity and depth, solid and fluid volume fractions, and pore‐fluid pressure. Non‐hydrostatic pore‐fluid pressure is produced by dilatancy, a state‐dependent property that links the depth‐averaged shear rate and volumetric strain rate of the granular phase. Pore‐pressure changes caused by shearing allow the model to exhibit rate‐dependent flow resistance, despite the fact that the basal shear traction involves only rate‐independent Coulomb friction. An analytical solution of simplified model equations shows that the onset of downslope motion can be accelerated or retarded by pore‐pressure change, contingent on whether dilatancy is positive or negative. A different analytical solution shows that such effects will likely be muted if downslope motion continues long enough, because dilatancy then evolves toward zero, and volume fractions and pore pressure concurrently evolve toward steady states.

  14. Changes in Bedform Shape at the Transition Between Upper Plane-Bed and Sheet-Flow Bedload Transport Regimes

    NASA Astrophysics Data System (ADS)

    Hernandez Moreira, R. R.; Huffman, B.; Vautin, D.; Viparelli, E.

    2015-12-01

    The interactions between flow hydrodynamics and bedform characteristics at the transition between upper plane-bed bedload transport regime and sheet-flow have not yet been thoroughly described and still remain poorly understood. The present study focuses on the experimental study of this transition in open channel mode. The experiments were performed in the hydraulic laboratory of the Department of Civil and Environmental Engineering of the University of South Carolina in a sediment-feed flume, 9-m long by 19-cm wide with uniform material sediment of geometric mean grain size diameter of 1.11 mm. Sediment feed rates ranged between 0.5 kg/min and 20 kg/min with two different flow rates of 20 l/s and 30 l/s. We recorded periodic measurements of water surface and bed elevation to estimate the global flow parameters, e.g. mean flow velocity and bed shear stress, and to determine when the flow and the sediment transport reached conditions of mobile bed equilibrium. We define mobile bed equilibrium as a condition in which the mean bed elevation does not change in time. At equilibrium, measurements of bed elevation fluctuations were taken with an ultrasonic transducer system at six discrete locations. In the runs with low and medium feed rates, i.e. smaller than ~12 kg/min, the long wavelength and small amplitude bedforms typical of the upper plane bed regime, which were observed in previous experimental work, formed and migrated downstream. In particular, with increasing feed rates, the amplitude of the bedforms decreases and their geometry changes, from well-defined triangular shapes, to rounded shapes to flat bed with very small amplitude, long wavelength undulations. The decrease in amplitude corresponds to a decrease in form drag and an increase in the thickness of the bedload layer. The ultrasonic measurements are analyzed to statistically describe the observed transition in terms of probability distribution functions of the bed elevation fluctuations.

  15. The fabrication and visible-near-infrared optical modulation of vanadium dioxide/silicon dioxide composite photonic crystal structure

    NASA Astrophysics Data System (ADS)

    Liang, Jiran; Li, Peng; Song, Xiaolong; Zhou, Liwei

    2017-12-01

    We demonstrated a visible and near-infrared light tunable photonic nanostructure, which is composed of vanadium dioxide (VO2) thin film and silicon dioxide (SiO2) ordered nanosphere arrays. The vanadium films were sputtered on two-dimensional (2D) SiO2 sphere arrays. VO2 thin films were prepared by rapid thermal annealing (RTA) method with different oxygen flow rates. The close-packed VO2 shell formed a continuous surface, the composition of VO2 films in the structure changed when the oxygen flow rates increased. The 2D VO2/SiO2 composite photonic crystal structure exhibited transmittance trough tunability and near-infrared (NIR) transmittance modulation. When the oxygen flow rate increased from 3 slpm to 4 slpm, the largest transmittance trough can be regulated from 904 to 929 nm at low temperature, the transmittance troughs also appear blue shift when the VO2 phase changes from insulator to metal. The composite nanostructure based on VO2 films showed visible transmittance tunability, which would provide insights into the glass color changing in smart windows.

  16. Damage Propagation Modeling for Aircraft Engine Prognostics

    NASA Technical Reports Server (NTRS)

    Saxena, Abhinav; Goebel, Kai; Simon, Don; Eklund, Neil

    2008-01-01

    This paper describes how damage propagation can be modeled within the modules of aircraft gas turbine engines. To that end, response surfaces of all sensors are generated via a thermo-dynamical simulation model for the engine as a function of variations of flow and efficiency of the modules of interest. An exponential rate of change for flow and efficiency loss was imposed for each data set, starting at a randomly chosen initial deterioration set point. The rate of change of the flow and efficiency denotes an otherwise unspecified fault with increasingly worsening effect. The rates of change of the faults were constrained to an upper threshold but were otherwise chosen randomly. Damage propagation was allowed to continue until a failure criterion was reached. A health index was defined as the minimum of several superimposed operational margins at any given time instant and the failure criterion is reached when health index reaches zero. Output of the model was the time series (cycles) of sensed measurements typically available from aircraft gas turbine engines. The data generated were used as challenge data for the Prognostics and Health Management (PHM) data competition at PHM 08.

  17. Fabrication and evaluation of a graphene oxide-based cantilever-type flow-meter for subsonic gas flow rate measurement

    NASA Astrophysics Data System (ADS)

    Hamdollahi, Hassan; Rahbar-Shahrouzi, Javad

    2018-05-01

    In this paper, a cantilever-type flow meter was fabricated to measure the rate of air flow in turbulent subsonic regimes such as purged gases. In the fabrication process, a piezoresistive material was coated on an interdigitated electric board as a substrate. The piezoresistive layer was a blend of latex as the polymeric matrix and graphene oxide as the sensing nanomaterial agent, which was reduced by solvothermal reduction method. The piezoresistive blend was dip-coated on a substrate with dotted pattern and was then reduced at 240 °C for 1 h in every coating step. When an air flow passed over the surface of the cantilever beam, the beam was bent in the downward direction, resulting in small variations in the resistance of the piezoresistive layer and a change in the bending angle of the cantilever which were measured simultaneously. The air flow rate was acquired via calibrating electrical resistance changes by Arduino and Wheatstone bridge circuit. The blending angle of the substrate caused by the interaction between the airflow and the cantilever and recorded by the camera and image processing was ultimately compared with the simulation results. The flow meter accuracy as a percentage of full scale (% FS) was calculated to be  ±5.8%, and mean deviation was equal to 2.1 (% FS) with the appropriate response time of 0.70 s at the air flow range of 100‑240 m s‑1. Highlights • A cantilever-type flow meter was fabricated to measure the high-speed air flow rate. • The sensitive piezoresistive material was composed of GO and latex. • The dip-coating method was used to deposit the piezoresistive layer on the fiberglass substrate. • The impact of effective parameters on the performance of the flow meter was investigated. • A simulation study was performed and the results were compared with the experimental data.

  18. Acute and chronic changes in brain activity with deep brain stimulation for refractory depression.

    PubMed

    Conen, Silke; Matthews, Julian C; Patel, Nikunj K; Anton-Rodriguez, José; Talbot, Peter S

    2018-04-01

    Deep brain stimulation is a potential option for patients with treatment-refractory depression. Deep brain stimulation benefits have been reported when targeting either the subgenual cingulate or ventral anterior capsule/nucleus accumbens. However, not all patients respond and optimum stimulation-site is uncertain. We compared deep brain stimulation of the subgenual cingulate and ventral anterior capsule/nucleus accumbens separately and combined in the same seven treatment-refractory depression patients, and investigated regional cerebral blood flow changes associated with acute and chronic deep brain stimulation. Deep brain stimulation-response was defined as reduction in Montgomery-Asberg Depression Rating Scale score from baseline of ≥50%, and remission as a Montgomery-Asberg Depression Rating Scale score ≤8. Changes in regional cerebral blood flow were assessed using [ 15 O]water positron emission tomography. Remitters had higher relative regional cerebral blood flow in the prefrontal cortex at baseline and all subsequent time-points compared to non-remitters and non-responders, with prefrontal cortex regional cerebral blood flow generally increasing with chronic deep brain stimulation. These effects were consistent regardless of stimulation-site. Overall, no significant regional cerebral blood flow changes were apparent when deep brain stimulation was acutely interrupted. Deep brain stimulation improved treatment-refractory depression severity in the majority of patients, with consistent changes in local and distant brain regions regardless of target stimulation. Remission of depression was reached in patients with higher baseline prefrontal regional cerebral blood flow. Because of the small sample size these results are preliminary and further evaluation is necessary to determine whether prefrontal cortex regional cerebral blood flow could be a predictive biomarker of treatment response.

  19. Changes in blood flow due to stented parent artery expansion in an intracranial aneurysm.

    PubMed

    Mori, Futoshi; Ohta, Makoto; Matsuzawa, Teruo

    2015-01-01

    Stent placement is thought to obstruct the inflow of blood to an aneurysm. However, we introduced parent artery expansion and demonstrated that this may reduce the blood flow by the stent. In our previous study using idealized shapes, the results showed that flow reduction was greater than 22.2%, even if the expansion rate was only 6%. Furthermore, the parent artery expansion is predominantly caused by the effect of flow reduction as compared to that of flow reduction due to the obstruction of flow under stent placement. However, a realistic shape is complex and the blood flow also becomes complex flow. It is not understood whether the results of flow in the idealized shape are reflective of flow from a realistic 3D model. Therefore, we examined the effect of parent artery expansion using a realistic model. The aim is to clarify the effects of parent artery expansion on inflow rate, wall shear stress, and oscillatory shear index. We used a patient-specific geometry of a human internal carotid artery with an aneurysm. The geometry of parent artery expansion due to oversized stent constructed based on the voronoi diagram. We performed calculations in the unsteady-state situations using constructed models. The complexity of the flow in the aneurysm decreases in case of expanded parent artery. The inflow rate decreases by 33.6% immediately after parent artery expansion alone without a stent. The effect of the parent artery expansion on flow reduction is larger than that of the obstruction flow by stent placement. In addition, wall shear stress and oscillatory shear index on the aneurysm wall decrease by change in blood flow due to the parent artery expansion. The effects of the parent artery expansion in a realistic aneurysm model with different stent lengths were evaluated on the basis of a numerical simulation. Although the flow was complex, the parent artery expansion with stent reduces the inflow to the aneurysm and wall shear stress and oscillatory shear index on the aneurysm. Therefore, we suggest that changes in the blood flow because of the parent artery expansion may be identified and, sometimes, is more effective than the obstruction flow due to the stent placement.

  20. Opposed-flow Flame Spread Over Solid Fuels in Microgravity: the Effect of Confined Spaces

    NASA Astrophysics Data System (ADS)

    Wang, Shuangfeng; Hu, Jun; Xiao, Yuan; Ren, Tan; Zhu, Feng

    2015-09-01

    Effects of confined spaces on flame spread over thin solid fuels in a low-speed opposing flow is investigated by combined use of microgravity experiments and computations. The flame behaviors are observed to depend strongly on the height of the flow tunnel. In particular, a non-monotonic trend of flame spread rate versus tunnel height is found, with the fastest flame occurring in the 3 cm high tunnel. The flame length and the total heat release rate from the flame also change with tunnel height, and a faster flame has a larger length and a higher heat release rate. The computation analyses indicate that a confined space modifies the flow around the spreading flame. The confinement restricts the thermal expansion and accelerates the flow in the streamwise direction. Above the flame, the flow deflects back from the tunnel wall. This inward flow pushes the flame towards the fuel surface, and increases oxygen transport into the flame. Such a flow modification explains the variations of flame spread rate and flame length with tunnel height. The present results suggest that the confinement effects on flame behavior in microgravity should be accounted to assess accurately the spacecraft fire hazard.

  1. Transient response of sap flow to wind speed.

    PubMed

    Chu, Chia R; Hsieh, Cheng-I; Wu, Shen-Yuang; Phillips, Nathan G

    2009-01-01

    Transient responses of sap flow to step changes in wind speed were experimentally investigated in a wind tunnel. A Granier-type sap flow sensor was calibrated and tested in a cylindrical tube for analysis of its transient time response. Then the sensor was used to measure the transient response of a well-watered Pachira macrocarpa plant to wind speed variations. The transient response of sap flow was described using the resistance-capacitance model. The steady sap flow rate increased as the wind speed increased at low wind speeds. Once the wind speed exceeded 8.0 m s(-1), the steady sap flow rate did not increase further. The transpiration rate, measured gravimetrically, showed a similar trend. The response of nocturnal sap flow to wind speed variation was also measured and compared with the results in the daytime. Under the same wind speed, the steady sap flow rate was smaller than that in the daytime, indicating differences between diurnal and nocturnal hydraulic function, and incomplete stomatal closure at night. In addition, it was found that the temporal response of the Granier sensor is fast enough to resolve the transient behaviour of water flux in plant tissue.

  2. Mass transfer in thin films under counter-current gas: experiments and numerical study

    NASA Astrophysics Data System (ADS)

    Lucquiaud, Mathieu; Lavalle, Gianluca; Schmidt, Patrick; Ausner, Ilja; Wehrli, Marc; O Naraigh, Lennon; Valluri, Prashant

    2016-11-01

    Mass transfer in liquid-gas stratified flows is strongly affected by the waviness of the interface. For reactive flows, the chemical reactions occurring at the liquid-gas interface also influence the mass transfer rate. This is encountered in several technological applications, such as absorption units for carbon capture. We investigate the absorption rate of carbon dioxide in a liquid solution. The experimental set-up consists of a vertical channel where a falling film is sheared by a counter-current gas flow. We measure the absorption occurring at different flow conditions, by changing the liquid solution, the liquid flow rate and the gas composition. With the aim to support the experimental results with numerical simulations, we implement in our level-set flow solver a novel module for mass transfer taking into account a variant of the ghost-fluid formalism. We firstly validate the pure mass transfer case with and without hydrodynamics by comparing the species concentration in the bulk flow to the analytical solution. In a final stage, we analyse the absorption rate in reactive flows, and try to reproduce the experimental results by means of numerical simulations to explore the active role of the waves at the interface.

  3. Performance of a new carbon dioxide absorbent, Yabashi lime® as compared to conventional carbon dioxide absorbent during sevoflurane anesthesia in dogs.

    PubMed

    Kondoh, Kei; Atiba, Ayman; Nagase, Kiyoshi; Ogawa, Shizuko; Miwa, Takashi; Katsumata, Teruya; Ueno, Hiroshi; Uzuka, Yuji

    2015-08-01

    In the present study, we compare a new carbon dioxide (CO2) absorbent, Yabashi lime(®) with a conventional CO2 absorbent, Sodasorb(®) as a control CO2 absorbent for Compound A (CA) and Carbon monoxide (CO) productions. Four dogs were anesthetized with sevoflurane. Each dog was anesthetized with four preparations, Yabashi lime(®) with high or low-flow rate of oxygen and control CO2 absorbent with high or low-flow rate. CA and CO concentrations in the anesthetic circuit, canister temperature and carbooxyhemoglobin (COHb) concentration in the blood were measured. Yabashi lime(®) did not produce CA. Control CO2 absorbent generated CA, and its concentration was significantly higher in low-flow rate than a high-flow rate. CO was generated only in low-flow rate groups, but there was no significance between Yabashi lime(®) groups and control CO2 absorbent groups. However, the CO concentration in the circuit could not be detected (≤5ppm), and no change was found in COHb level. Canister temperature was significantly higher in low-flow rate groups than high-flow rate groups. Furthermore, in low-flow rate groups, the lower layer of canister temperature in control CO2 absorbent group was significantly higher than Yabashi lime(®) group. CA and CO productions are thought to be related to the composition of CO2 absorbent, flow rate and canister temperature. Though CO concentration is equal, it might be safer to use Yabashi lime(®) with sevoflurane anesthesia in dogs than conventional CO2 absorbent at the point of CA production.

  4. Gas Exchange Models for a Flexible Insect Tracheal System.

    PubMed

    Simelane, S M; Abelman, S; Duncan, F D

    2016-06-01

    In this paper two models for movement of respiratory gases in the insect trachea are presented. One model considers the tracheal system as a single flexible compartment while the other model considers the trachea as a single flexible compartment with gas exchange. This work represents an extension of Ben-Tal's work on compartmental gas exchange in human lungs and is applied to the insect tracheal system. The purpose of the work is to study nonlinear phenomena seen in the insect respiratory system. It is assumed that the flow inside the trachea is laminar, and that the air inside the chamber behaves as an ideal gas. Further, with the isothermal assumption, the expressions for the tracheal partial pressures of oxygen and carbon dioxide, rate of volume change, and the rates of change of oxygen concentration and carbon dioxide concentration are derived. The effects of some flow parameters such as diffusion capacities, reaction rates and air concentrations on net flow are studied. Numerical simulations of the tracheal flow characteristics are performed. The models developed provide a mathematical framework to further investigate gas exchange in insects.

  5. Numerical prediction of micro-channel LD heat sink operated with antifreeze based on CFD method

    NASA Astrophysics Data System (ADS)

    Liu, Gang; Liu, Yang; Wang, Chao; Wang, Wentao; Wang, Gang; Tang, Xiaojun

    2014-12-01

    To theoretically study the feasibility of antifreeze coolants applied as cooling fluids for high power LD heat sink, detailed Computational Fluid Dynamics (CFD) analysis of liquid cooled micro-channels heat sinks is presented. The performance operated with antifreeze coolant (ethylene glycol aqueous solution) compared with pure water are numerical calculated for the heat sinks with the same micro-channels structures. The maximum thermal resistance, total pressure loss (flow resistance), thermal resistance vs. flow-rate, and pressure loss vs. flow-rate etc. characteristics are numerical calculated. The results indicate that the type and temperature of coolants plays an important role on the performance of heat sinks. The whole thermal resistance and pressure loss of heat sinks increase significantly with antifreeze coolants compared with pure water mainly due to its relatively lower thermal conductivity and higher fluid viscosity. The thermal resistance and pressure loss are functions of the flow rate and operation temperature. Increasing of the coolant flow rate can reduce the thermal resistance of heat sinks; meanwhile increase the pressure loss significantly. The thermal resistance tends to a limit with increasing flow rate, while the pressure loss tends to increase exponentially with increasing flow rate. Low operation temperature chiefly increases the pressure loss rather than thermal resistance due to the remarkable increasing of fluid viscosity. The actual working point of the cooling circulation system can be determined on the basis of the pressure drop vs. flow rate curve for the micro-channel heat sink and that for the circulation system. In the same system, if the type or/and temperature of the coolant is changed, the working point is accordingly influenced, that is, working flow rate and pressure is changed simultaneously, due to which the heat sink performance is influenced. According to the numerical simulation results, if ethylene glycol aqueous solution is applied instead of pure water as the coolant under the same or a higher working temperature, the available output of optical power will decrease due to the worse heat sink performance; if applied under a lower working temperature(0 °C, -20 °C), although the heat sink performance become worse, however the temperature difference of heat transfer rises more significantly, the available output of optical power will increase on the contrary.

  6. Method of measuring the mass flow rate of a substance entering a cocurrent fluid stream

    DOEpatents

    Cochran, Jr., Henry D.

    1978-04-11

    This invention relates to an improved method of monitoring the mass flow rate of a substance entering a cocurrent fluid stream. The method very basically consists of heating equal sections of the fluid stream above and below the point of entry of the substance to be monitored, and measuring and comparing the resulting change in temperature of the sections. Advantage is taken of the difference in thermal characteristics of the fluid and the substance to be measured to correlate temperature differences in the sections above and below the substance feed point for providing an indication of the mass flow rate of the substance.

  7. Analyses of Magnetic Resonance Imaging of Cerebrospinal Fluid Dynamics Pre and Post Short and Long-Duration Space Flights

    NASA Technical Reports Server (NTRS)

    Alperin, Noam; Barr, Yael; Lee, Sang H.; Mason,Sara; Bagci, Ahmet M.

    2015-01-01

    Preliminary results are based on analyses of data from 17 crewmembers. The initial analysis compares pre to post-flight changes in total cerebral blood flow (CBF) and craniospinal CSF flow volume. Total CBF is obtained by summation of the mean flow rates through the 4 blood vessels supplying the brain (right and left internal carotid and vertebral arteries). Volumetric flow rates were obtained using an automated lumen segmentation technique shown to have 3-4-fold improved reproducibility and accuracy over manual lumen segmentation (6). Two cohorts, 5 short-duration and 8 long-duration crewmembers, who were scanned within 3 to 8 days post landing were included (4 short-duration crewmembers with MRI scans occurring beyond 10 days post flight were excluded). The VIIP Clinical Practice Guideline (CPG) classification is being used initially as a measure for VIIP syndrome severity. Median CPG scores of the short and long-duration cohorts were similar, 2. Mean preflight total CBF for the short and long-duration cohorts were similar, 863+/-144 and 747+/-119 mL/min, respectively. Percentage CBF changes for all short duration crewmembers were 11% or lower, within the range of normal physiological fluctuations in healthy individuals. In contrast, in 4 of the 8 long-duration crewmembers, the change in CBF exceeded the range of normal physiological fluctuation. In 3 of the 4 subjects an increase in CBF was measured. Large pre to post-flight changes in the craniospinal CSF flow volume were found in 6 of the 8 long-duration crewmembers. Box-Whisker plots of the CPG and the percent CBF and CSF flow changes for the two cohorts are shown in Figure 4. Examples of CSF flow waveforms for a short and two long-duration (CPG 0 and 3) are shown in Figure 5. Changes in CBF and CSF flow dynamics larger than normal physiological fluctuations were observed in the long-duration crewmembers. Changes in CSF flow were more pronounced than changes in CBF. Decreased CSF flow dynamics were observed in a subject with VIIP signs. Study limitations include a slightly longer landing-to-MRI scan period for the short-duration cohort and limited sensitivity of the subjective discrete ordinal CPG scale. This limitation can be overcome by using imaging based parametric measures of VIIP severity such as globe deformation measures.

  8. Hydrological and biogeochemical response of the Mediterranean Sea to freshwater flow changes for the end of the 21st century.

    PubMed

    Macias, Diego; Stips, Adolf; Garcia-Gorriz, Elisa; Dosio, Alessandro

    2018-01-01

    We evaluate the changes on the hydrological (temperature and salinity) and biogeochemical (phytoplankton biomass) characteristics of the Mediterranean Sea induced by freshwater flow modifications under two different scenarios for the end of the 21st century. An ensemble of four regional climate model realizations using different global circulation models at the boundary and different emission scenarios are used to force a single ocean model for the Mediterranean Sea. Freshwater flow is modified according to the simulated changes in the precipitation rates for the different rivers' catchment regions. To isolate the effect resulting from a change in freshwater flow, model results are evaluated against a 'baseline' simulation realized assuming a constant inflow equivalent to climatologic values. Our model results indicate that sea surface salinity could be significantly altered by freshwater flow modification in specific regions and that the affected area and the sign of the anomaly are highly dependent on the used climate model and emission scenario. Sea surface temperature and phytoplankton biomass, on the contrary, show no coherent spatial pattern but a rather widespread scattered response. We found in open-water regions a significant negative relationship between sea surface temperature anomalies and phytoplankton biomass anomalies. This indicates that freshwater flow modification could alter the vertical stability of the water column throughout the Mediterranean Sea, by changing the strength of vertical mixing and consequently upper water fertilization. In coastal regions, however, the correlation between sea temperature anomalies and phytoplankton biomass is positive, indicating a larger importance of the physiological control of growth rates by temperature.

  9. Cerebral blood flow response to changes in arterial carbon dioxide tension during hypothermic cardiopulmonary bypass in children

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kern, F.H.; Ungerleider, R.M.; Quill, T.J.

    1991-04-01

    We examined the relationship of changes in partial pressure of carbon dioxide on cerebral blood flow responsiveness in 20 pediatric patients undergoing hypothermic cardiopulmonary bypass. Cerebral blood flow was measured during steady-state hypothermic cardiopulmonary bypass with the use of xenon 133 clearance methodology at two different arterial carbon dioxide tensions. During these measurements there was no significant change in mean arterial pressure, nasopharyngeal temperature, pump flow rate, or hematocrit value. Cerebral blood flow was found to be significantly greater at higher arterial carbon dioxide tensions (p less than 0.01), so that for every millimeter of mercury rise in arterial carbonmore » dioxide tension there was a 1.2 ml.100 gm-1.min-1 increase in cerebral blood flow. Two factors, deep hypothermia (18 degrees to 22 degrees C) and reduced age (less than 1 year), diminished the effect carbon dioxide had on cerebral blood flow responsiveness but did not eliminate it. We conclude that cerebral blood flow remains responsive to changes in arterial carbon dioxide tension during hypothermic cardiopulmonary bypass in infants and children; that is, increasing arterial carbon dioxide tension will independently increase cerebral blood flow.« less

  10. Bone tissue engineering: the role of interstitial fluid flow

    NASA Technical Reports Server (NTRS)

    Hillsley, M. V.; Frangos, J. A.

    1994-01-01

    It is well established that vascularization is required for effective bone healing. This implies that blood flow and interstitial fluid (ISF) flow are required for healing and maintenance of bone. The fact that changes in bone blood flow and ISF flow are associated with changes in bone remodeling and formation support this theory. ISF flow in bone results from transcortical pressure gradients produced by vascular and hydrostatic pressure, and mechanical loading. Conditions observed to alter flow rates include increases in venous pressure in hypertension, fluid shifts occurring in bedrest and microgravity, increases in vascularization during the injury-healing response, and mechanical compression and bending of bone during exercise. These conditions also induce changes in bone remodeling. Previously, we hypothesized that interstitial fluid flow in bone, and in particular fluid shear stress, serves to mediate signal transduction in mechanical loading- and injury-induced remodeling. In addition, we proposed that a lack or decrease of ISF flow results in the bone loss observed in disuse and microgravity. The purpose of this article is to review ISF flow in bone and its role in osteogenesis.

  11. Avoid cruising on the uroflowmeter: evaluation of cruising artifact on spinning disc flowmeters in an experimental setup.

    PubMed

    Addla, Sanjai Kumar; Marri, Rajender Reddy; Daayana, Sai Lakshmi; Irwin, Paul

    2010-09-01

    The aim of our study was to access the variability of maximum flow rate (Q(max)), average flow rate (Q(av)) and flow pattern while varying the point of impact of flow on the flowmeter. Water was delivered through a motorised tube holder in a standardised experimental set up. Flow was directed in 4 different directions on the funnel; 1) Periphery, 2) Base, 3) Centre and, 4) in a cruising motion from the periphery of the funnel to the centre and back again. The variation in the Q(max), Q(av) and the flow pattern were studied at 4 different flow rates. The variables recorded when the flow was directed at the centre of the funnel was taken as baseline. There was a significant difference in the Q(max) and Q(av)when the point of impact was at the periphery or in a cruising motion compared to the centre. The difference was more marked with cruising motion with a characteristic flow pattern. The maximum percentage difference in Q(av) was 4.1%, whereas the difference in Q(max) was higher at 16.6% on comparing crusing motion with the values from the centre. We have demonstrated a significant variation in Q(max), Q(av) and flow pattern with change in the point of impact on the flowmeter. Though the changes in Q(av) were statistically significant, the alteration in the recorded Q(max) values was more striking. Our study emphasizes the importance of combining Q(av) and flow pattern along with Q(max) in interpretation of results of uroflowmetry. © 2010 Wiley-Liss, Inc.

  12. Aerodynamic control of NASP-type vehicles through Vortex manipulation. Volume 1: Static water tunnel tests

    NASA Technical Reports Server (NTRS)

    Suarez, Carlos J.; Ng, T. Terry; Ong, Lih-Yenn; Malcolm, Gerald N.

    1993-01-01

    Water tunnel tests were conducted on a NASP-type configuration to evaluate different pneumatic Forebody Vortex Control (FVC) methods. Flow visualization and yawing moment measurements were performed at angles of attack from 0 deg to 30 deg. The pneumatic techniques tested included jet and slot blowing. In general, blowing can be used efficiently to manipulate the forebody vortices at angles of attack greater than 20 deg. These vortices are naturally symmetric up to alpha = 25 deg and asymmetric between 25 deg and 30 deg angle of attack. Results indicate that tangential aft jet blowing is the most promising method for this configuration. Aft jet blowing produces a yawing moment towards the blowing side and the trends with blowing rate are well behaved. The size of the nozzle is not the dominant factor in the blowing process; the change in the blowing 'momentum,' i.e., the product of the mass flow rate and the velocity of the jet, appears to be the important parameter in the water tunnel (incompressible and unchoked flow at the nozzle exit). Forward jet blowing is very unpredictable and sensitive to mass flow rate changes. Slot blowing (with the exception of very low blowing rates) acts as a flow 'separator'; it promotes early separation on the blow side, producing a yawing moment toward the non-blowing side for the C(sub mu) range investigated.

  13. Longitudinal flow of endolymph measured by distribution of tetraethylammonium and choline in scala media.

    PubMed

    Syková, E; Syka, J; Johnstone, B M; Yates, G K

    1987-01-01

    Longitudinal endolymph flow rate in the guinea pig cochlea was measured by determining the rate of migration of extrinsic ions, tetraethylammonium chloride (TEA) or choline, with a potassium sensitive ion-selective microelectrode (ISM). Low concentrations of iontophoretically injected TEA were detected with the ISM at various distances from the injection electrode. The results were variable when the ISM was used to record spread of TEA from turn II to turn I and vice versa. However, consistent data were obtained when the TEA spread was measured at different electrode separations (0.2, 0.5, 0.7 mm) within turn II. Electrode locations were systematically exchanged without changing their distance, i.e. the ISM electrode was placed basally or apically with respect to the TEA electrode. Comparison of data with a model, which combines the bulk diffusion of TEA and the flow of endolymph, is consistent with a rate of endolymph flow in turn II of about 0.2 mm/min, apex to base. A similar value was also obtained with the iontophoretic injection of choline. The endolymph flow rate may be different in turn I as indicated by measurements of compound action potential (CAP) changes. However, the results of experiments when TEA spread is measured at large distances must be interpreted cautiously because TEA may enter cellular walls of the cochlear duct and alternative routes of transport may be involved.

  14. The effect of vacuum devices on penile hemodynamics

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Katz, P.G.; Haden, H.T.; Mulligan, T.

    1990-01-01

    External vacuum devices are being used increasingly for the management of erectile dysfunction. There is limited information regarding the effect of vacuum devices on penile blood flow and potential for ischemic penile injury. The penile xenon washout rate was measured before and after application of 2 vacuum systems in 15 subjects. Compared to flaccid state measurements the xenon washout rate did not change significantly with the Synergist Erection System but it was significantly reduced with the Osbon ErecAid System. However, the degree and duration of decrease in penile blood flow that may result in ischemic changes are unknown.

  15. Receptor-mediated binding of IgE-sensitized rat basophilic leukemia cells to antigen-coated substrates under hydrodynamic flow.

    PubMed Central

    Tempelman, L A; Hammer, D A

    1994-01-01

    The physiological function of many cells is dependent on their ability to adhere via receptors to ligand-coated surfaces under fluid flow. We have developed a model experimental system to measure cell adhesion as a function of cell and surface chemistry and fluid flow. Using a parallel-plate flow chamber, we measured the binding of rat basophilic leukemia cells preincubated with anti-dinitrophenol IgE antibody to polyacrylamide gels covalently derivatized with 2,4-dinitrophenol. The rat basophilic leukemia cells' binding behavior is binary: cells are either adherent or continue to travel at their hydrodynamic velocity, and the transition between these two states is abrupt. The spatial location of adherent cells shows cells can adhere many cell diameters down the length of the gel, suggesting that adhesion is a probabilistic process. The majority of experiments were performed in the excess ligand limit in which adhesion depends strongly on the number of receptors but weakly on ligand density. Only 5-fold changes in IgE surface density or in shear rate were necessary to change adhesion from complete to indistinguishable from negative control. Adhesion showed a hyperbolic dependence on shear rate. By performing experiments with two IgE-antigen configurations in which the kinetic rates of receptor-ligand binding are different, we demonstrate that the forward rate of reaction of the receptor-ligand pair is more important than its thermodynamic affinity in the regulation of binding under hydrodynamic flow. In fact, adhesion increases with increasing receptor-ligand reaction rate or decreasing shear rate, and scales with a single dimensionless parameter which compares the relative rates of reaction to fluid shear. Images FIGURE 2 FIGURE 3 FIGURE 6 FIGURE 8 FIGURE 10 PMID:8038394

  16. Stopped-flow studies of changes in fluorescence of 8-anilino-1-naphthalene sulfonic acid caused by magnesium and salt binding to yeast enolase.

    PubMed

    Brewer, J M

    1976-12-11

    Stopped-flow studies of magnesium and salt (potassium chloride and acetate) effects on yeast enolase were carried out by following 8-anilino-1-naphthalenesulfonic acid fluorescence changes. The fluorescence changes appear to be largely caused by subunit association and dissociation, though there is evidence in some reactions for large changes in fluorescence occurring within the dead time of the stopped-flow measurements. These data are combined with measurements of initial enzyme activity after incubation in various solvents with or without magnesium to obtain subunit association and dissociation rates. From these, it is concluded that magnesium and the salts act by directly changing the affinities of the subunits for each other, apparently by producing a rapid change in protein conformation.

  17. Remagnetization of lava flows spanning the last geomagnetic reversal

    NASA Astrophysics Data System (ADS)

    Vella, Jérôme; Carlut, Julie; Valet, Jean-Pierre; Goff, Maxime Le; Soler, Vicente; Lopes, Fernando

    2017-08-01

    Large directional changes of remanent magnetization within lava flows that cooled during geomagnetic reversals have been reported in several studies. A geomagnetic scenario implies extremely rapid geomagnetic changes of several degrees per day, thus difficult to reconcile with the rate of the earth's core liquid motions. So far, no complete rock magnetic model provides a clear explanation. We revisited lava flows sandwiched between an underlying reverse and an overlying normal polarity flow marking the last reversal in three distinct volcanic sequences of the La Palma Island (Canary archipelago, Spain) that are characterized by a gradual evolution of the direction of their remanent magnetization from bottom to top. Cleaning efficiency of thermal demagnetization was not improved by very rapid heating and cooling rates as well as by continuous demagnetization using a Triaxe magnetometer. We did not observe partial self-reversals and minor changes in magnetic grain sizes are not related to the within-flow directional changes. Microscopic observations indicate poor exsolution, which suggests post-cooling thermochemical remagnetization processes. This scenario is strongly reinforced by laboratory experiments that show large resistance to thermal demagnetization when thermoremanence was acquired over a long time period. We speculate that in the present situation exsolution was reactivated during in field reheating and yielded formation of new magnetite, yet magnetic domain state rearrangements could also play a role. Initial reheating when the overlying flow took place, albeit moderate (less than 200-300 °C), was enough to produce overlying components with significantly higher unblocking temperatures.

  18. Solute transport with time-variable flow paths during upward and downward flux in a heterogeneous unsaturated porous medium

    NASA Astrophysics Data System (ADS)

    Cremer, Clemens; Neuweiler, Insa; Bechtold, Michel; Vanderborght, Jan

    2014-05-01

    To acquire knowledge of solute transport through the unsaturated zone in the shallow subsurface is decisive to assess groundwater quality, nutrient cycling or to plan remediation strategies. The shallow subsurface is characterized by structural heterogeneity and strongly influenced by atmospheric conditions. This leads to changing flow directions, strong temporal changes in saturation and heterogeneous water fluxes during infiltration and evaporation events. Recent studies (e.g. Lehmann and Or, 2009; Bechtold et al.,2011) demonstrated the importance of lateral flow and solute transport during evaporation conditions (upward flux). The heterogeneous structure in these studies was constructed using two types of sand with strong material contrasts and arranged in parallel with a vertical orientation. Lateral transport and redistribution of solute from coarse to fine media was observed deeper in the soil column and from fine to coarse close to the soil surface. However, if boundary conditions are reversed due to precipitation, the flow field is not necessarily reversed in the same manner, resulting in entirely different transport patterns for downward and upward flow. Therefore, considering net-flow rates alone is misleading when describing transport under those conditions. In this contribution we analyze transport of a solute in the shallow subsurface to assess effects resulting from the temporal change of heterogeneous soil structures due to dynamic flow conditions. Two-dimensional numerical simulations of unsaturated flow and transport are conducted using a coupled finite volume and random walk particle tracking algorithm to quantify solute transport and leaching rates. Following previous studies (Lehmann and Or, 2009; Bechtold et al., 2011), the chosen domain is composed of two materials, coarse and fine sand, arranged in parallel with a vertical orientation. Hence, one sharp interface of strong material heterogeneity is induced. During evaporation both sands are assumed to stay under liquid-flow dominated evaporation conditions ("stage 1"). Simulations considering dynamic (infiltration-evaporation) and steady (solely infiltration) boundary conditions are carried out. The influence of dynamic boundary conditions (intensity and duration of precipitation and evaporation events) is examined in a multitude of simulations. If flow rates smaller than the saturated hydraulic conductivity of both materials are chosen to be applied as boundary condition, simulation results indicate that the flow field within the domain is exactly reversed. However, if applied flow rates exceed the saturated hydraulic conductivity of one material, the flow field is not just reversed, but different flow paths during downward and upward flow are observed. Results show the tendency of faster solute leaching under dynamic boundary conditions compared to steady infiltration conditions with the same net-infiltration rate. We use a double domain transport method as an upscaled model to reproduce vertically averaged concentration profiles with net flux only and compare the model parameters for information about flow dynamics and soil heterogeneity.

  19. Pulse waveform analysis on temporal changes in ocular blood flow due to caffeine intake: a comparative study between habitual and non-habitual groups.

    PubMed

    Ismail, Aishah; Bhatti, Mehwish S; Faye, Ibrahima; Lu, Cheng Kai; Laude, Augustinus; Tang, Tong Boon

    2018-06-06

    To evaluate and compare the temporal changes in pulse waveform parameters of ocular blood flow (OBF) between non-habitual and habitual groups due to caffeine intake. This study was conducted on 19 healthy subjects (non-habitual 8; habitual 11), non-smoking and between 21 and 30 years of age. Using laser speckle flowgraphy (LSFG), three areas of optical nerve head were analyzed which are vessel, tissue, and overall, each with ten pulse waveform parameters, namely mean blur rate (MBR), fluctuation, skew, blowout score (BOS), blowout time (BOT), rising rate, falling rate, flow acceleration index (FAI), acceleration time index (ATI), and resistive index (RI). Two-way mixed ANOVA was used to determine the difference between every two groups where p < 0.05 is considered significant. There were significant differences between the two groups in several ocular pulse waveform parameters, namely MBR (overall, vessel, tissue), BOT (overall), rising rate (overall), and falling rate (vessel), all with p < 0.05. In addition, the ocular pulse waveform parameters, i.e., MBR (overall), skew (tissue), and BOT (tissue) showed significant temporal changes within the non-habitual group, but not within the habitual group. The temporal changes in parameters MBR (vessel, tissue), skew (overall, vessel), BOT (overall, vessel), rising rate (overall), falling rate (overall, vessel), and FAI (tissue) were significant for both groups (habitual and non-habitual) in response to caffeine intake. The experiment results demonstrated caffeine does modulate OBF significantly and response differently in non-habitual and habitual groups. Among all ten parameters, MBR and BOT were identified as the suitable biomarkers to differentiate between the two groups.

  20. Determining Coolant Flow Rate Distribution In The Fuel-Modified TRIGA Plate Reactor

    NASA Astrophysics Data System (ADS)

    Puji Hastuti, Endiah; Widodo, Surip; Darwis Isnaini, M.; Geni Rina, S.; Syaiful, B.

    2018-02-01

    TRIGA 2000 reactor in Bandung is planned to have the fuel element replaced, from cylindrical uranium and zirconium-hydride (U-ZrH) alloy to U3Si2-Al plate type of low enriched uranium of 19.75% with uranium density of 2.96 gU/cm3, while the reactor power is maintained at 2 MW. This change is planned to anticipate the discontinuity of TRIGA fuel element production. The selection of this plate-type fuel element is supported by the fact that such fuel type has been produced in Indonesia and used in MPR-30 safely since 2000. The core configuration of plate-type-fuelled TRIGA reactor requires coolant flow rate through each fuel element channel in order to meet its safety function. This paper is aimed to describe the results of coolant flow rate distribution in the TRIGA core that meets the safety function at normal operation condition, physical test, shutdown, and at initial event of loss of coolant flow due power supply interruption. The design analysis to determine coolant flow rate in this paper employs CAUDVAP and COOLODN computation code. The designed coolant flow rate that meets the safety criteria of departure from nucleate boiling ratio (DNBR), onset of flow instability ratio (OFIR), and ΔΤ onset of nucleate boiling (ONB), indicates that the minimum flow rate required to cool the plate-type fuelled TRIGA core at 2 MW is 80 kg/s. Therefore, it can be concluded that the operating limitation condition (OLC) for the minimum flow rate is 80 kg/s; the 72 kg/s is to cool the active core; while the minimum flow rate for coolant flow rate drop is limited to 68 kg/s with the coolant inlet temperature 35°C. This thermohydraulic design also provides cooling for 4 positions irradiation position (IP) utilization and 1 central irradiation position (CIP) with end fitting inner diameter (ID) of 10 mm and 20 mm, respectively.

  1. Human red blood cell behavior under homogeneous extensional flow in a hyperbolic-shaped microchannel.

    PubMed

    Yaginuma, T; Oliveira, M S N; Lima, R; Ishikawa, T; Yamaguchi, T

    2013-01-01

    It is well known that certain pathological conditions result in a decrease of red blood cells (RBCs) deformability and subsequently can significantly alter the blood flow in microcirculation, which may block capillaries and cause ischemia in the tissues. Microfluidic systems able to obtain reliable quantitative measurements of RBC deformability hold the key to understand and diagnose RBC related diseases. In this work, a microfluidic system composed of a microchannel with a hyperbolic-shaped contraction followed by a sudden expansion is presented. We provide a detailed quantitative description of the degree of deformation of human RBCs under a controlled homogeneous extensional flow field. We measured the deformation index (DI) as well as the velocity of the RBCs travelling along the centerline of the channel for four different flow rates and analyze the impact of the particle Reynolds number. The results show that human RBC deformation tends to reach a plateau value in the region of constant extensional rate, the value of which depends on the extension rate. Additionally, we observe that the presence of a sudden expansion downstream of the hyperbolic contraction modifies the spatial distribution of cells and substantially increases the cell free layer (CFL) downstream of the expansion plane similarly to what is seen in other expansion flows. Beyond a certain value of flow rate, there is only a weak effect of inlet flow rates on the enhancement of the downstream CFL. These in vitro experiments show the potential of using microfluidic systems with hyperbolic-shaped microchannels both for the separation of the RBCs from plasma and to assess changes in RBC deformability in physiological and pathological situations for clinical purposes. However, the selection of the geometry and the identification of the most suitable region to evaluate the changes on the RBC deformability under extensional flows are crucial if microfluidics is to be used as an in vitro clinical methodology to detect circulatory diseases.

  2. Human red blood cell behavior under homogeneous extensional flow in a hyperbolic-shaped microchannel

    PubMed Central

    Yaginuma, T.; Oliveira, M. S. N.; Lima, R.; Ishikawa, T.; Yamaguchi, T.

    2013-01-01

    It is well known that certain pathological conditions result in a decrease of red blood cells (RBCs) deformability and subsequently can significantly alter the blood flow in microcirculation, which may block capillaries and cause ischemia in the tissues. Microfluidic systems able to obtain reliable quantitative measurements of RBC deformability hold the key to understand and diagnose RBC related diseases. In this work, a microfluidic system composed of a microchannel with a hyperbolic-shaped contraction followed by a sudden expansion is presented. We provide a detailed quantitative description of the degree of deformation of human RBCs under a controlled homogeneous extensional flow field. We measured the deformation index (DI) as well as the velocity of the RBCs travelling along the centerline of the channel for four different flow rates and analyze the impact of the particle Reynolds number. The results show that human RBC deformation tends to reach a plateau value in the region of constant extensional rate, the value of which depends on the extension rate. Additionally, we observe that the presence of a sudden expansion downstream of the hyperbolic contraction modifies the spatial distribution of cells and substantially increases the cell free layer (CFL) downstream of the expansion plane similarly to what is seen in other expansion flows. Beyond a certain value of flow rate, there is only a weak effect of inlet flow rates on the enhancement of the downstream CFL. These in vitro experiments show the potential of using microfluidic systems with hyperbolic-shaped microchannels both for the separation of the RBCs from plasma and to assess changes in RBC deformability in physiological and pathological situations for clinical purposes. However, the selection of the geometry and the identification of the most suitable region to evaluate the changes on the RBC deformability under extensional flows are crucial if microfluidics is to be used as an in vitro clinical methodology to detect circulatory diseases. PMID:24404073

  3. Flow rate calibration to determine cell-derived microparticles and homogeneity of blood components.

    PubMed

    Noulsri, Egarit; Lerdwana, Surada; Kittisares, Kulvara; Palasuwan, Attakorn; Palasuwan, Duangdao

    2017-08-01

    Cell-derived microparticles (MPs) are currently of great interest to screening transfusion donors and blood components. However, the current approach to counting MPs is not affordable for routine laboratory use due to its high cost. The current study aimed to investigate the potential use of flow-rate calibration for counting MPs in whole blood, packed red blood cells (PRBCs), and platelet concentrates (PCs). The accuracy of flow-rate calibration was investigated by comparing the platelet counts of an automated counter and a flow-rate calibrator. The concentration of MPs and their origins in whole blood (n=100), PRBCs (n=100), and PCs (n=92) were determined using a FACSCalibur. The MPs' fold-changes were calculated to assess the homogeneity of the blood components. Comparing the platelet counts conducted by automated counting and flow-rate calibration showed an r 2 of 0.6 (y=0.69x+97,620). The CVs of the within-run and between-run variations of flow-rate calibration were 8.2% and 12.1%, respectively. The Bland-Altman plot showed a mean bias of -31,142platelets/μl. MP enumeration revealed both the difference in MP levels and their origins in whole blood, PRBCs, and PCs. Screening the blood components demonstrated high heterogeneity of the MP levels in PCs when compared to whole blood and PRBCs. The results of the present study suggest the accuracy and precision of flow-rate calibration for enumerating MPs. This flow-rate approach is affordable for assessing the homogeneity of MPs in blood components in routine laboratory practice. Copyright © 2017 Elsevier Ltd. All rights reserved.

  4. End-to-End Flow Control for Visual-Haptic Communication under Bandwidth Change

    NASA Astrophysics Data System (ADS)

    Yashiro, Daisuke; Tian, Dapeng; Yakoh, Takahiro

    This paper proposes an end-to-end flow controller for visual-haptic communication. A visual-haptic communication system transmits non-real-time packets, which contain large-size visual data, and real-time packets, which contain small-size haptic data. When the transmission rate of visual data exceeds the communication bandwidth, the visual-haptic communication system becomes unstable owing to buffer overflow. To solve this problem, an end-to-end flow controller is proposed. This controller determines the optimal transmission rate of visual data on the basis of the traffic conditions, which are estimated by the packets for haptic communication. Experimental results confirm that in the proposed method, a short packet-sending interval and a short delay are achieved under bandwidth change, and thus, high-precision visual-haptic communication is realized.

  5. Slip-Flow and Heat Transfer of a Non-Newtonian Nanofluid in a Microtube

    PubMed Central

    Niu, Jun; Fu, Ceji; Tan, Wenchang

    2012-01-01

    The slip-flow and heat transfer of a non-Newtonian nanofluid in a microtube is theoretically studied. The power-law rheology is adopted to describe the non-Newtonian characteristics of the flow, in which the fluid consistency coefficient and the flow behavior index depend on the nanoparticle volume fraction. The velocity profile, volumetric flow rate and local Nusselt number are calculated for different values of nanoparticle volume fraction and slip length. The results show that the influence of nanoparticle volume fraction on the flow of the nanofluid depends on the pressure gradient, which is quite different from that of the Newtonian nanofluid. Increase of the nanoparticle volume fraction has the effect to impede the flow at a small pressure gradient, but it changes to facilitate the flow when the pressure gradient is large enough. This remarkable phenomenon is observed when the tube radius shrinks to micrometer scale. On the other hand, we find that increase of the slip length always results in larger flow rate of the nanofluid. Furthermore, the heat transfer rate of the nanofluid in the microtube can be enhanced due to the non-Newtonian rheology and slip boundary effects. The thermally fully developed heat transfer rate under constant wall temperature and constant heat flux boundary conditions is also compared. PMID:22615961

  6. Numerical studies of transverse curvature effects on transonic flow stability

    NASA Technical Reports Server (NTRS)

    Macaraeg, M. G.; Daudpota, Q. I.

    1992-01-01

    A numerical study of transverse curvature effects on compressible flow temporal stability for transonic to low supersonic Mach numbers is presented for axisymmetric modes. The mean flows studied include a similar boundary-layer profile and a nonsimilar axisymmetric boundary-layer solution. The effect of neglecting curvature in the mean flow produces only small quantitative changes in the disturbance growth rate. For transonic Mach numbers (1-1.4) and aerodynamically relevant Reynolds numbers (5000-10,000 based on displacement thickness), the maximum growth rate is found to increase with curvature - the maximum occurring at a nondimensional radius (based on displacement thickness) between 30 and 100.

  7. Computational Hemodynamic Analysis for the Diagnosis of Atherosclerotic Changes in Intracranial Aneurysms: A Proof-of-Concept Study Using 3 Cases Harboring Atherosclerotic and Nonatherosclerotic Aneurysms Simultaneously

    PubMed Central

    Endo, Hidenori; Niizuma, Kuniyasu; Endo, Toshiki; Funamoto, Kenichi; Ohta, Makoto; Tominaga, Teiji

    2016-01-01

    This was a proof-of-concept computational fluid dynamics (CFD) study designed to identify atherosclerotic changes in intracranial aneurysms. We selected 3 patients with multiple unruptured aneurysms including at least one with atherosclerotic changes and investigated whether an image-based CFD study could provide useful information for discriminating the atherosclerotic aneurysms. Patient-specific geometries were constructed from three-dimensional data obtained using rotational angiography. Transient simulations were conducted under patient-specific inlet flow rates measured by phase-contrast magnetic resonance velocimetry. In the postanalyses, we calculated time-averaged wall shear stress (WSS), oscillatory shear index, and relative residence time (RRT). The volume of blood flow entering aneurysms through the neck and the mean velocity of blood flow inside aneurysms were examined. We applied the age-of-fluid method to quantitatively assess the residence of blood inside aneurysms. Atherosclerotic changes coincided with regions exposed to disturbed blood flow, as indicated by low WSS and long RRT. Blood entered aneurysms in phase with inlet flow rates. The mean velocities of blood inside atherosclerotic aneurysms were lower than those inside nonatherosclerotic aneurysms. Blood in atherosclerotic aneurysms was older than that in nonatherosclerotic aneurysms, especially near the wall. This proof-of-concept study demonstrated that CFD analysis provided detailed information on the exchange and residence of blood that is useful for the diagnosis of atherosclerotic changes in intracranial aneurysms. PMID:27703491

  8. Rate Dependence of Elementary Rearrangements and Spatiotemporal Correlations in the 3D Flow of Soft Solids

    NASA Astrophysics Data System (ADS)

    Vasisht, Vishwas V.; Dutta, Sudeep K.; Del Gado, Emanuela; Blair, Daniel L.

    2018-01-01

    We use a combination of confocal microscopy, rheology, and molecular dynamics simulations to investigate jammed emulsions under shear, by analyzing the 3D droplets rearrangements in the shear frame. Our quantitative analysis of local dynamics reveals elementary nonaffine rearrangements that underlie the onset of the flow at small strains. We find that the mechanism of unjamming and the upturn in the material flow curve are associated to a qualitative change in spatiotemporal correlations of such rearrangements with the applied shear rate. At high shear rates, droplet clusters follow coordinated, stringlike motion. Conversely, at low shear rates, the elementary nonaffine rearrangements exhibit longer-ranged correlations, with complex spatiotemporal patterns. The 3D microscopic details provide novel insights into the specific features of the material flow curve, common to a large class of technologically relevant soft disordered solids and new fundamental ingredients for constitutive models.

  9. Transitions to improved confinement regimes induced by changes in heating in zero-dimensional models for tokamak plasmas

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zhu, H.; Chapman, S. C.; Max Planck Institute for the Physics of Complex Systems, Dresden

    2014-06-15

    It is shown that rapid substantial changes in heating rate can induce transitions to improved energy confinement regimes in zero-dimensional models for tokamak plasma phenomenology. We examine for the first time the effect of step changes in heating rate in the models of Kim and Diamond [Phys. Rev. Lett. 90, 185006 (2003)] and Malkov and Diamond [Phys. Plasmas 16, 012504 (2009)], which nonlinearly couple the evolving temperature gradient, micro-turbulence, and a mesoscale flow; and in the extension of Zhu et al. [Phys. Plasmas 20, 042302 (2013)], which couples to a second mesoscale flow component. The temperature gradient rises, as doesmore » the confinement time defined by analogy with the fusion context, while micro-turbulence is suppressed. This outcome is robust against variation of heating rise time and against introduction of an additional variable into the model. It is also demonstrated that oscillating changes in heating rate can drive the level of micro-turbulence through a period-doubling path to chaos, where the amplitude of the oscillatory component of the heating rate is the control parameter.« less

  10. Implication of surface modified NZVI particle retention in the porous media: Assessment with the help of 1-D transport model

    NASA Astrophysics Data System (ADS)

    Raychoudhury, Trishikhi; Surasani, Vikranth Kumar

    2017-06-01

    Retention of surface-modified nanoscale zero-valent iron (NZVI) particles in the porous media near the point of injection has been reported in the recent studies. Retention of excess particles in porous media can alter the media properties. The main objectives of this study are, therefore, to evaluate the effect of particle retention on the porous media properties and its implication on further NZVI particle transport under different flow conditions. To achieve the objectives, a one-dimensional transport model is developed by considering particle deposition, detachment, and straining mechanisms along with the effect of changes in porosity resulting from retention of NZVI particles. Two different flow conditions are considered for simulations. The first is a constant Darcy's flow rate condition, which assumes a change in porosity, causes a change in pore water velocity and the second, is a constant head condition, which assumes the change in porosity, influence the permeability and hydraulic conductivity (thus Darcy's flow rate). Overall a rapid decrease in porosity was observed as a result of high particle retention near the injection points resulting in a spatial distribution of deposition rate coefficient. In the case of constant head condition, the spatial distribution of Darcy's velocities is predicted due to variation in porosity and hydraulic conductivity. The simulation results are compared with the data reported from the field studies; which suggests straining is likely to happen in the real field condition.

  11. Effect of cevimeline on salivary components in patients with Sjögren syndrome.

    PubMed

    Suzuki, Kimihiro; Matsumoto, Mitsuyo; Nakashima, Masahiro; Takada, Kunio; Nakanishi, Takashi; Okada, Makoto; Ohsuzu, Fumitaka

    2005-05-01

    The aim of this study is to clarify the effects of cevimeline on various components in human saliva, such as immunoglobulin A (IgA), lysozyme, alpha-amylase and squamous cell carcinoma (SCC) antigen. Twelve female patients with Sjögren syndrome (SS) and 14 healthy women were enrolled. After the first saliva collection, one capsule (30 mg) of cevimeline was administered to each subject. Saliva was collected again after 90 min. The salivary flow rate and concentration of each component were measured. In both groups the salivary flow rate and amylase concentration were significantly increased by cevimeline. The lysozyme and IgA concentrations did not change significantly in both groups. The SCC antigen concentration did not change significantly in the SS group, but it decreased significantly in the control group. The secretion rates of amylase and IgA showed significant increases in both groups. The secretion rate of lysozyme significantly increased only in the control group, while the secretion rate of SCC significantly increased only in the SS group. Cevimeline augments not only the salivary flow rate but also the secretion rate of some digestive and/or defense factors from infections. It may be beneficial for SS patients to continue taking cevimeline to prevent oral infections, and other serious sequelae. Copyright (c) 2005 S. Karger AG, Basel.

  12. Fluid Flow Prediction with Development System Interwell Connectivity Influence

    NASA Astrophysics Data System (ADS)

    Bolshakov, M.; Deeva, T.; Pustovskikh, A.

    2016-03-01

    In this paper interwell connectivity has been studied. First of all, literature review of existing methods was made which is divided into three groups: Statistically-Based Methods, Material (fluid) Propagation-Based Methods and Potential (pressure) Change Propagation-Based Method. The disadvantages of the first and second groups are as follows: methods do not involve fluid flow through porous media, ignore any changes of well conditions (BHP, skin factor, etc.). The last group considers changes of well conditions and fluid flow through porous media. In this work Capacitance method (CM) has been chosen for research. This method is based on material balance and uses weight coefficients lambdas to assess well influence. In the next step synthetic model was created for examining CM. This model consists of an injection well and a production well. CM gave good results, it means that flow rates which were calculated by analytical method (CM) show matching with flow rate in model. Further new synthetic model was created which includes six production and one injection wells. This model represents seven-spot pattern. To obtain lambdas weight coefficients, the delta function was entered using by minimization algorithm. Also synthetic model which has three injectors and thirteen producer wells was created. This model simulates seven-spot pattern production system. Finally Capacitance method (CM) has been adjusted on real data of oil Field Ω. In this case CM does not give enough satisfying results in terms of field data liquid rate. In conclusion, recommendations to simplify CM calculations were given. Field Ω is assumed to have one injection and one production wells. In this case, satisfying results for production rates and cumulative production were obtained.

  13. Relationship between dyspnea, peak expiratory flow rate and wheeze in obstructive lung disease.

    PubMed

    Srisawai, P

    1997-05-01

    The relationship between dyspnea and airway obstruction is complex, and it is unclear to what extent measures of each correlate in patients with obstructive lung disease (OLD). Thus, the correlation between subjective assessment of dyspnea (dyspnea score using modified Borg scale) and objective assessment of dyspnea (peak expiratory flow rate using Mini Wright Peak Flow Meter and wheeze score using stethoscope) before and after bronchodilator (1 mg of turbutaline sulphate) were studied in 115 patients (62 males, 53 females) with OLD attending the chest clinic of Royal Irrigation Hospital, Nonthaburi, Thailand. The mean age of these patients was 47.4 +/- 16.4 years. Good correlations were found (r = 0.37 to 0.52; p < 0.001) but dyspnea scores were better correlated with wheeze scores than peak expiratory flow rates. The change in dyspnea scores after bronchodilator also correlated with the change in peak expiratory flow rates and the change in wheeze scores (r = 0.22; p < 0.02 and r = 0.28; p < 0.005 respectively). Analyzing a subgroup of 48 dyspneic patients (prebronchodilator dyspnea score of 2 or more) revealed the following response groups: those with either a bronchodilator or dyspnea response alone, both together, or neither. Twenty-three patients (47.92 per cent) responded both subjectively and objectively. One (2.08 per cent) had a bronchodilator response only. Twenty (41.66 per cent) had a dyspnea response only, while four (8.33 per cent) had neither measurable response. The present study suggests that the assessment of dyspnea by using dyspnea score is vital and may be specially helpful in a situation where the objective assessment cannot be performed. In some individuals the subjective assessment of response to bronchodilator may be at least as valuable as objective data.

  14. Influence of Hydrological Flow Paths on Rates and Forms of Nitrogen Losses from Mediterranean Watersheds

    NASA Astrophysics Data System (ADS)

    Lohse, K. A.; Sanderman, J.; Amundson, R. G.

    2005-12-01

    Patterns of precipitation and runoff in California are changing and likely to influence the structure and functioning of watersheds. Studies have demonstrated that hydrologic flushing during seasonal transitions in Mediterranean ecosystems can exert a strong control on nitrogen (N) export, yet few studies have examined the influence of different hydrological flow paths on rates and forms of nitrogen (N) losses. Here we illuminate the influence of variations in precipitation and hydrological pathways on the rate and form of N export along a toposequence of a well-characterized Mediterranean catchment in northern California. As a part of a larger study examining particulate and dissolved carbon loss, we analyzed seasonal patterns of dissolved organic nitrogen (DON), nitrate and ammonium concentrations in rainfall, throughfall, matrix and preferential flow, and stream samples over the course of one water year. We also analyzed seasonal soil N dynamics along this toposequence. During the transition to the winter rain season, but prior to any soil water displacement to the stream, DON and nitrate moved through near-surface soils as preferential flow. Once hillslope soils became saturated, saturated subsurface flow flushed nitrate from the hollow resulting in high stream nitrate/DON concentrations. Between storms, stream nitrate/DON concentrations were lower and appeared to reflect deep subsurface water flow chemistry. During the transition to the wet season, rates of soil nitrate production were high in the hollow relative to the hillslope soils. In the spring, these rates systematically declined as soil moisture decreased. Results from our study suggest seasonal fluctuations in soil moisture control soil N cycling and seasonal changes in the hydrological connection between hillslope soils and streams control the seasonal production and export of hydrologic N.

  15. Useful method to monitor the physiological effects of alcohol ingestion by combination of micro-integrated laser Doppler blood flow meter and arm-raising test.

    PubMed

    Iwasaki, Wataru; Nogami, Hirofumi; Ito, Hiroki; Gotanda, Takeshi; Peng, Yao; Takeuchi, Satoshi; Furue, Masutaka; Higurashi, Eiji; Sawada, Renshi

    2012-10-01

    Alcohol has a variety of effects on the human body, affecting both the sympathetic and parasympathetic nervous system. We examined the peripheral blood flow of alcohol drinkers using a micro-integrated laser Doppler blood flow meter (micro-electromechanical system blood flow sensor). An increased heart rate and blood flow was recorded at the earlobe after alcohol ingestion, and we observed strong correlation between blood flow, heart rate, and breath alcohol content in light drinkers; but not heavy drinkers. We also found that the amplitude of pulse waves measured at the fingertip during an arm-raising test significantly decreased on alcohol consumption, regardless of the individual's alcohol tolerance. Our micro-electromechanical system blood flow sensor successfully detected various physiological changes in peripheral blood circulation induced by alcohol consumption.

  16. Plasma Indicator Dispersion in Arteries of the Human Leg

    PubMed Central

    Bassingthwaighte, James B.

    2010-01-01

    Indicator-dilution curves were recorded from the femoral and dorsalis pedis arteries of five normal men after injections of indocyanine green into the superior vena cava or thoracic aorta. By considering the femoral curves as inputs to a mathematically linear system and the dorsalis pedis curves as outputs, transfer functions (the distribution of transit times) for the arterial segment between these sites were obtained in terms of a four-parameter model, the lagged normal density curve, over a sixfold range of flow rates. The parameters of the spread (dispersion) of 57 transfer functions were proportional to the mean transit time. The mean difference between transit time and appearance time was 0.30 t̄; the square root of the variances was 0.18 t̄. These linear relationships suggest that flow rate has no significant influence on dispersion and that, since no transition from laminar to turbulent flow was apparent, arterial flow characteristics were not significantly changed over a wide range of flow rates. The secondary implication is that the rate of spatial longitudinal spreading of indicator with distance traveled is primarily a function of the geometry of the arterial system, not of the rate of flow, and, therefore, that the spatial distribution at any instant is a function of this rate and of the distance traveled through the system. PMID:5330717

  17. MRI measurement of the temporal evolution of relative CMRO(2) during rat forepaw stimulation.

    PubMed

    Mandeville, J B; Marota, J J; Ayata, C; Moskowitz, M A; Weisskoff, R M; Rosen, B R

    1999-11-01

    This study reports the first measurement of the relative cerebral metabolic rate of oxygen utilization (rCMRO(2)) during functional brain activation with sufficient temporal resolution to address the dynamics of blood oxygen level-dependent (BOLD) MRI signal. During rat forepaw stimulation, rCMRO(2) was determined in somatosensory cortex at 3-sec intervals, using a model of BOLD signal and measurements of the change in BOLD transverse relaxation rate, the resting state BOLD transverse relaxation rate, relative cerebral blood flow (rCBF), and relative cerebral blood volume (rCBV). Average percentage changes from 10 to 30 sec after onset of forepaw stimulation for rCBF, rCBV, rCMRO(2), and BOLD relaxation rate were 62 +/- 16, 17 +/- 2, 19 +/- 17, and -26 +/- 12, respectively. A poststimulus undershoot in BOLD signal was quantitatively attributed to the temporal mismatch between changes in blood flow and volume, and not to the role of oxygen metabolism. Magn Reson Med 42:944-951, 1999. Copyright 1999 Wiley-Liss, Inc.

  18. Simple Radiowave-Based Method For Measuring Peripheral Blood Flow Project

    NASA Technical Reports Server (NTRS)

    Oliva-Buisson, Yvette J.

    2014-01-01

    Project objective is to design small radio frequency based flow probes for the measurement of blood flow velocity in peripheral arteries such as the femoral artery and middle cerebral artery. The result will be the technological capability to measure peripheral blood flow rates and flow changes during various environmental stressors such as microgravity without contact to the individual being monitored. This technology may also lead to an easier method of detecting venous gas emboli during extravehicular activities.

  19. Changes in scalp and cortical blood flow during hyperventilation measured with diffusing-wave spectroscopy

    NASA Astrophysics Data System (ADS)

    Li, Jun; Ninck, Markus; Gisler, Thomas

    2009-07-01

    Changes in scalp and cortical blood flow induced by voluntary hyperventilation are investigated by near-infrared diffusing-wave spectroscopy. The temporal intensity autocorrelation function g(2) (τ) of multiply scattered light is recorded from the forehead of subjects during hyperventilation. Blood flow within the sampled tissue volume is estimated by the mean decay rate of g(2) (τ) . Data measured from six subjects show that the pattern of the hemodynamic response during 50 s hyperventilation is rather complicated: within the first 10 s, in three subjects an initial increase in blood flow is observed; from 10 s to 20 s, the mean blood flow is smaller than its baseline value for all six subjects; for the duration from 20 s to 30 s, the blood flow increases again. However, after 30 s the change is not consistent across subjects. Further study on one of these subjects by using two receivers probing the blood flow in the cortex and in the superficial layers simultaneously, reveals that during hyperventilation, the direction of change in blood flow within the scalp is opposite to the one in the brain. This helps to understand the complicated hemodynamic response observed in our measurements.

  20. Influence of flow variability on floodplain formation and destruction, Little Missouri River, North Dakota

    USGS Publications Warehouse

    Miller, J.R.; Friedman, J.M.

    2009-01-01

    Resolving observations of channel change into separate planimetric measurements of floodplain formation and destruction reveals distinct relations between these processes and the flow regime. We analyzed a time sequence of eight bottomland images from 1939 to 2003 along the Little Missouri River, North Dakota, to relate geomorphic floodplain change to flow along this largely unregulated river. At the decadal scale, floodplain formation and destruction varied independently. Destruction was strongly positively correlated with the magnitude of infrequent high flows that recur every 5-10 yr, whereas floodplain formation was negatively correlated with the magnitude of frequent low flows exceeded 80% of the time. At the century scale, however, a climatically induced decrease in peak flows has reduced the destruction rate, limiting the area made available for floodplain formation. The rate of destruction was not uniform across the floodplain. Younger surfaces were consistently destroyed at a higher rate than older surfaces, suggesting that throughput of contaminants would have occurred more rapidly than predicted by models that assume uniform residence time of sediment across the floodplain. Maps of floodplain ages produced by analysis of sequential floodplain images are similar to maps of forest ages produced through dendrochronology, confirming the assumption of dendrogeomorphic studies that riparian tree establishment in this system is limited to recent channel locations. ?? 2009 Geological Society of America.

  1. Characterization of local fluid flow in 3D porous construct characterized by Fourier domain Doppler optical coherence tomography

    NASA Astrophysics Data System (ADS)

    Bagnaninchi, P. O.; Yang, Y.; El Haj, A.; Hinds, M. T.; Wang, R. K.

    2007-02-01

    In order to achieve functional tissue with the correct biomechanical properties it is critical to stimulate mechanically the cells. Perfusion bioreactor induces fluid shear stress that has been well characterized for two-dimensional culture where both simulation and experimental data are available. However these results can't be directly translated to tissue engineering that makes use of complex three-dimensional porous scaffold. Moreover, stimulated cells produce extensive extra-cellular matrix (ECM) that alter dramatically the micro-architecture of the constructs, changing the local flow dynamic. In this study a Fourier domain Doppler optical coherent tomography (FD-DOCT) system working at 1300nm with a bandwidth of 50nm has been used to determine the local flow rate inside different types of porous scaffolds used in tissue engineering. Local flow rates can then be linearly related, for Newtonian fluid, to the fluid shear stress occurring on the pores wall. Porous chitosan scaffolds (\\fgr 1.5mm x 3mm) with and without a central 250 μm microchannel have been produced by a freeze-drying technique. This techniques allow us to determine the actual shear stress applied to the cells and to optimise the input flow rate consequently, but also to relate the change of the flow distribution to the amount of ECM production allowing the monitoring of tissue formation.

  2. [Impacts on skin blood flow under moving cupping along meridians in different directions].

    PubMed

    Tian, Yu-Ying; Wang, Guang-Jun; Huang, Tao; Jia, Shu-Yong; Zhang, Yu-Qin; Zhang, Wei-Bo

    2013-03-01

    To compare the impacts on skin blood flow between moving cupping following the meridian running direction and that against the running direction. JLG-2 meridian cupping drainage instru ment was used for moving cupping on the back along the Bladder Meridian running course in either single direction for 20 times. The cupping device was Bian stone cup, 44 mm in inner diameter, negative pressure from -0.03 to -0.04 MPa. PeriScan PIM II laser Doppler perfusion imager was used to observe the changes in skin blood flow on the running course of the Bladder Meridian with cup moved up and down and in the same region on the contralateral Bladder Meridian. Blood flow was measured before cupping, at the immediate time after cupping and 10 min after cupping separately. Fourteen healthy volunteers received the test. The measuring region was subdivided into a moving cupping area, an upstream area, a downstream area, a contralateral moving cupping area, a contralateral upstream area and a contralateral downstream area. The mean blood flow was calculated in each area. Blood flow was increased significantly in each area and was more apparently increased in the moving cupping area. In comparison of the changing rate of blood flow between cupping following the meridian running direction and that against the running direction, it was only found that the changing rate in the upstream area of moving cupping against the running direction was significantly higher than that following the running direction (P < 0.05). The differences were not statistically significant in comparison among the other areas. Additionally, the changing rates of blood flow in the upstream and downstream area of the Bladder Meridian were increased significantly as compared with the contralateral Bladder Meridian. The local effects are similar between moving cupping following the meridian running direction and that against the running direction. The abscopal effect of moving cupping against the running direction is superior to that following the running direction. It is suggested that the dual-directional moving cupping is applicable for the treatment of local disorders and the abscopal effect is better with moving cupping against the meridian running direction.

  3. Comparative performance of fixed-film biological filters: Application of reactor theory

    USGS Publications Warehouse

    Watten, B.J.; Sibrell, P.L.

    2006-01-01

    Nitrification is classified as a two-step consecutive reaction where R1 represents the rate of formation of the intermediate product NO2-N and R2 represents the rate of formation of the final product NO3-N. The relative rates of R1 and R2 are influenced by reactor type characterized hydraulically as plug-flow, plug-flow with dispersion and mixed-flow. We develop substrate conversion models for fixed-film biofilters operating in the first-order kinetic regime based on application of chemical reactor theory. Reactor type, inlet conditions and the biofilm kinetic constants Ki (h-1) are used to predict changes in NH4-N, NO2-N, NO3-N and BOD5. The inhibiting effects of the latter on R1 and R2 were established based on the ?? relation, e.g.:{A formula is presented}where BOD5,max is the concentration that causes nitrification to cease and N is a variable relating Ki to increasing BOD5. Conversion models were incorporated in spreadsheet programs that provided steady-state concentrations of nitrogen and BOD5 at several points in a recirculating aquaculture system operating with input values for fish feed rate, reactor volume, microscreen performance, make-up and recirculating flow rates. When rate constants are standardized, spreadsheet use demonstrates plug-flow reactors provide higher rates of R1 and R2 than mixed-flow reactors thereby reducing volume requirements for target concentrations of NH4-N and NO2-N. The benefit provided by the plug-flow reactor varies with hydraulic residence time t as well as the effective vessel dispersion number, D/??L. Both reactor types are capable of providing net increases in NO2-N during treatment but the rate of decrease in the mixed-flow case falls well behind that predicted for plug-flow operation. We show the potential for a positive net change in NO2-N increases with decreases in the dimensionless ratios K2, (R2 )/K1,( R1 ) and [NO2-N]/[NH4-N] and when the product K1, (R1) t provides low to moderate NH4-N conversions. Maintaining high levels of the latter reduces the effective reactor utilization rate (%) defined here as (RNavg/RNmax)100 where RNavg is the mean reactive nitrogen concentration ([NH4-N] + [NO2-N]) within the reactor, and RNmax represents the feed concentration of the same. Low utilization rates provide a hedge against unexpected increases in substrate loading and reduce water pumping requirements but force use of elevated reactor volumes. Further ?? effects on R1 and R2 can be reduced through use of a tanks-in-series versus a single mixed-flow reactor configuration and by improving the solids removal efficiency of microscreen treatment.

  4. An estimation of intracranial blood flow in the new-born infant.

    PubMed Central

    Cross, K W; Dear, P R; Hathorn, M K; Hyams, A; Kerslake, D M; Milligan, D W; Rahilly, P M; Stothers, J K

    1979-01-01

    1. A non-invasive method for the estimation of the intracranial blood flow of the new-born infant is described, and results obtained with it are presented. 2. The technique is a novel application of the principle of blood flow measurement by venous occlusion plethysmography. It is possible to apply a plethysmographic technique to the neonatal cranium because the presence of open sutures between the component bones permits small, but readily measurable, changes in intracranial volume to occur. 3. Skull volume changes are calculated from changes in the occipito-frontal circumference of the cranium as recorded and measured with a mercury-in-Silastic strain gauge. 4. The jugular veins in the baby's neck are occluded by finger pressure and there follows an increase in skull volume, which is rapid at first, but which decreases exponentially as venous drainage diverts to non-occluded channels such as the vertebral venous plexus. At the instant of jugular occlusion the rate of skull volume increase is representative of the rate of flow in the jugular vessels prior to occlusion, and so provides an index of the relative magnitude of the intracranial blood flow. The method thus allows changes in intracranial blood flow to be followed. When occlusion is released cranial volume decreases, initially rapidly, but slowing exponentially as resting volume is regained. 5. A theoretical model of the events occurring during the inflow and outflow phases has been developed, and a formula derived which allows an estimation to be made of the flow of blood through uncompressed channels. The measured value of jugular blood flow can then be augmented to an estimate of total intracranial flow. 6. The mean cerebral blood flow of sixteen normal babies was estimated to be 40 ml. 100 g-1.min-1 (S.D. = +/- 11.63). Images Fig. 2 Fig. 6 PMID:458665

  5. Detection of water quality trends at high, median, and low flow in a Catskill Mountain stream, New York, through a new statistical method

    USGS Publications Warehouse

    Murdoch, Peter S.; Shanley, James B.

    2006-01-01

    The effects of changes in acid deposition rates resulting from the Clean Air Act Amendments of 1990 should first appear in stream waters during rainstorms and snowmelt, when the surface of the watershed is most hydrologically connected to the stream. Early detection of improved stream water quality is possible if trends at high flow could be separately determined. Trends in concentrations of sulfate (SO42−), nitrate (NO3−), calcium plus magnesium (Ca2++Mg2+), and acid‐neutralizing capacity (ANC) in Biscuit Brook, Catskill Mountains, New York, were assessed through segmented regression analysis (SRA). The method uses annual concentration‐to‐discharge relations to predict concentrations for specific discharges, then compares those annual values to determine trends at specific discharge levels. Median‐flow trends using SRA were comparable to those predicted by the seasonal Kendall tau test and a multiple regression residual analysis. All of these methods show that stream water SO42− concentrations have decreased significantly since 1983; Ca2++Mg2+ concentrations have decreased at a steady but slower rate than SO42−; and ANC shows no trend. The new SRA method, however, reveals trends that differ at specified flow levels. ANC has increased, and NO3−concentrations have decreased at high flows, but neither has changed as significantly at low flows. The general downward trend in SO42− flattened at median flow and reversed at high flow between 1997 and 2002. The reversal of the high‐flow SO42− trend is consistent with increases in SO42− concentrations in both precipitation and soil solutions at Biscuit Brook. Separate calculation of high‐flow trends provides resource managers with an early detection system for assessing changes in water quality resulting from changes in acidic deposition.

  6. Laboratory Observations of Sand Ripple Evolution in a Small Oscillatory Flow Tunnel

    NASA Astrophysics Data System (ADS)

    Calantoni, J.; Palmsten, M. L.; Chu, J.; Landry, B. J.; Penko, A.

    2014-12-01

    The dynamics of sand ripples are vital to understanding numerous coastal processes such as sediment transport, wave attenuation, boundary layer development, and seafloor acoustic properties. Experimental work was conducted in a small oscillatory flow tunnel at the Sediment Dynamics Laboratory at the Naval Research Laboratory, Stennis Space Center. Six different monochromatic oscillatory forcings, three with velocity asymmetry and three without, were used to investigate sand ripple dynamics using a unimodal grain size distribution with D50=0.65 mm. The experiments represent an extension of previous work using bimodal grain size distributions. A DSLR camera with a 180-degree fisheye lens collected images of the sediment bed profile every 2 seconds to resolve changes in ripple geometries and migration rates resulting from the different flow conditions for over 127 hours (229,388 images). Matlab © algorithms undistorted the fisheye images and quantified the ripple geometries, wavelengths, heights, and migration rates as a function of flow forcing. The mobility number was kept nearly constant by increasing and decreasing the semi-excursion amplitude and the wave frequency, respectively. We observed distinct changes in ripple geometry and migration rate for the pair of oscillatory forcings having nearly identical mobility numbers. The results suggested that the commonly used mobility number might not be appropriate to characterize ripple geometry or migration rates.

  7. Role of distal reabsorption and peritubular environment in glomerulotubular balance.

    NASA Technical Reports Server (NTRS)

    Schrier, R. W.; Humphreys, M. H.

    1972-01-01

    Total kidney glomerulotubular balance was examined during aortic constriction and release in saline-loaded dogs and in dogs undergoing water diuresis. Aortic constriction lowered the glomerular filtration rate by 45% in both groups, and glomerulotubular balance, as judged by changes in absolute sodium reabsorption, was also comparable. During water diuresis, a linear relationship was observed between free water clearance and urine flow during all maneuvers, suggesting that distal sodium reabsorption is related primarily to distal delivery. The results suggest that if alterations in the peritubular environment are responsible for the changes in tubular sodium reabsorption during aortic constriction in the saline- or water-loaded dog, then a change in renal plasma flow, and presumably delivery rate of oncotic force, may be the most likely mediator.

  8. Effects of Structural Flexibility on Motorcycle Straight Running Stability by using Energy Flow Method

    NASA Astrophysics Data System (ADS)

    Marumo, Yoshitaka; Katayama, Tsuyoshi

    This study uses the energy flow method to analyze how structural flexibility affects the motorcycle wobble and weave modes. Lateral bending of the front fork and torsion of the main frame affect the wobble mode stability. These are based on the gyroscopic effect of the front wheel in the steering motion by considering structural flexibility. At high speeds, lateral bending of the front fork and torsion of the rear swing arm more significantly affect the weave mode stability. These are primarily due to the phase changes of the external force generated by the yaw rate in the lateral motion. The phase change of the yaw rate force in the lateral motion originates from the phase change of the tire side forces.

  9. The renal response to electrical stimulation of renal efferent sympathetic nerves in the anaesthetized greyhound.

    PubMed Central

    Poucher, S M; Karim, F

    1991-01-01

    1. The effect of direct electrical stimulation of the renal efferent nerves upon renal haemodynamics and function was studied in greyhounds anaesthetized with chloralose and artificially ventilated. The left kidney was neurally and vascularly isolated, and perfused with blood from one of the femoral arteries at a constant pressure of 99 +/- 1 mmHg. Renal blood flow was measured with a cannulating electromagnetic flow probe placed in the perfusion circuit, glomerular filtration rate by creatinine clearance, urinary sodium excretion by flame photometry and solute excretion by osmometry. Beta-Adrenergic receptor activation was blocked by the infusion of dl-propranolol (17 micrograms kg-1 min-1). The peripheral ends of the ligated renal nerves were stimulated at 0.5, 1.0, 1.5 and 2.0 Hz. 2. At 0.5 Hz frequency only osmolar excretion was significantly reduced (10.3 +/- 3.2%, P less than 0.05, n = 6). Reductions in sodium excretion (53.6 +/- 8.5%, P less than 0.01, n = 6) and water excretion (26.9 +/- 8.0%, P less than 0.05, n = 6) and further reductions of osmolar excretion (20.7 +/- 3.7%, P less than 0.01, n = 6) were observed at 1.0 Hz; however, these were observed in the absence of significant changes in renal blood flow and glomerular filtration rate. Significant reductions were observed in glomerular filtration rate at 1.5 Hz (16.3 +/- 4.1%, P less than 0.02, n = 5) and in renal blood flow at 2.0 Hz (13.1 +/- 4.0%, P less than 0.05, n = 5). Further reductions in urine flow and sodium excretion were also observed at these higher frequencies. 3. These results clearly show that significant changes in renal tubular function can occur in the absence of changes in renal blood flow and glomerular filtration rate when the renal nerves are stimulated electrically from a zero baseline activity up to a frequency of 1.5 Hz. Higher frequencies caused significant changes in both renal haemodynamics and function. PMID:2023113

  10. A novel miniature dynamic microfluidic cell culture platform using electro-osmosis diode pumping.

    PubMed

    Chang, Jen-Yung; Wang, Shuo; Allen, Jeffrey S; Lee, Seong Hyuk; Chang, Suk Tai; Choi, Young-Ki; Friedrich, Craig; Choi, Chang Kyoung

    2014-07-01

    An electro-osmosis (EOS) diode pumping platform capable of culturing cells in fluidic cellular micro-environments particularly at low volume flow rates has been developed. Diode pumps have been shown to be a viable alternative to mechanically driven pumps. Typically electrokinetic micro-pumps were limited to low-concentration solutions (≤10 mM). In our approach, surface mount diodes were embedded along the sidewalls of a microchannel to rectify externally applied alternating current into pulsed direct current power across the diodes in order to generate EOS flows. This approach has for the first time generated flows at ultra-low flow rates (from 2.0 nl/s to 12.3 nl/s) in aqueous solutions with concentrations greater than 100 mM. The range of flow was generated by changing the electric field strength applied to the diodes from 0.5 Vpp/cm to 10 Vpp/cm. Embedding an additional diode on the upper surface of the enclosed microchannel increased flow rates further. We characterized the diode pump-driven fluidics in terms of intensities and frequencies of electric inputs, pH values of solutions, and solution types. As part of this study, we found that the growth of A549 human lung cancer cells was positively affected in the microfluidic diode pumping system. Though the chemical reaction compromised the fluidic control overtime, the system could be maintained fully functional over a long time if the solution was changed every hour. In conclusion, the advantage of miniature size and ability to accurately control fluids at ultra-low volume flow rates can make this diode pumping system attractive to lab-on-a-chip applications and biomedical engineering in vitro studies.

  11. A novel miniature dynamic microfluidic cell culture platform using electro-osmosis diode pumping

    PubMed Central

    Chang, Jen-Yung; Wang, Shuo; Allen, Jeffrey S.; Lee, Seong Hyuk; Chang, Suk Tai; Choi, Young-Ki; Friedrich, Craig; Choi, Chang Kyoung

    2014-01-01

    An electro-osmosis (EOS) diode pumping platform capable of culturing cells in fluidic cellular micro-environments particularly at low volume flow rates has been developed. Diode pumps have been shown to be a viable alternative to mechanically driven pumps. Typically electrokinetic micro-pumps were limited to low-concentration solutions (≤10 mM). In our approach, surface mount diodes were embedded along the sidewalls of a microchannel to rectify externally applied alternating current into pulsed direct current power across the diodes in order to generate EOS flows. This approach has for the first time generated flows at ultra-low flow rates (from 2.0 nl/s to 12.3 nl/s) in aqueous solutions with concentrations greater than 100 mM. The range of flow was generated by changing the electric field strength applied to the diodes from 0.5 Vpp/cm to 10 Vpp/cm. Embedding an additional diode on the upper surface of the enclosed microchannel increased flow rates further. We characterized the diode pump-driven fluidics in terms of intensities and frequencies of electric inputs, pH values of solutions, and solution types. As part of this study, we found that the growth of A549 human lung cancer cells was positively affected in the microfluidic diode pumping system. Though the chemical reaction compromised the fluidic control overtime, the system could be maintained fully functional over a long time if the solution was changed every hour. In conclusion, the advantage of miniature size and ability to accurately control fluids at ultra-low volume flow rates can make this diode pumping system attractive to lab-on-a-chip applications and biomedical engineering in vitro studies. PMID:25379101

  12. Condensation in One-Dimensional Dead-End Nanochannels.

    PubMed

    Zhong, Junjie; Zandavi, Seyed Hadi; Li, Huawei; Bao, Bo; Persad, Aaron H; Mostowfi, Farshid; Sinton, David

    2017-01-24

    Phase change at the nanoscale is at the heart of many biological and geological phenomena. The recent emergence and global implications of unconventional oil and gas production from nanoporous shale further necessitate a higher understanding of phase behavior at these scales. Here, we directly observe condensation and condensate growth of a light hydrocarbon (propane) in discrete sub-100 nm (∼70 nm) channels. Two different condensation mechanisms at this nanoscale are distinguished, continuous growth and discontinuous growth due to liquid bridging ahead of the meniscus, both leading to similar net growth rates. The growth rates agree well with those predicted by a suitably defined thermofluid resistance model. In contrast to phase change at larger scales (∼220 and ∼1000 nm cases), the rate of liquid condensate growth in channels of sub-100 nm size is found to be limited mainly by vapor flow resistance (∼70% of the total resistance here), with interface resistance making up the difference. The condensation-induced vapor flow is in the transitional flow regime (Knudsen flow accounting for up to 13% of total resistance here). Collectively, these results demonstrate that with confinement at sub-100 nm scales, such as is commonly found in porous shale and other applications, condensation conditions deviate from the microscale and larger bulk conditions chiefly due to vapor flow and interface resistances.

  13. Effects of changes in pumping on regional groundwater-flow paths, 2005 and 2010, and areas contributing recharge to discharging wells, 1990–2010, in the vicinity of North Penn Area 7 Superfund site, Montgomery County, Pennsylvania

    USGS Publications Warehouse

    Senior, Lisa A.; Goode, Daniel J.

    2017-06-06

    A previously developed regional groundwater flow model was used to simulate the effects of changes in pumping rates on groundwater-flow paths and extent of recharge discharging to wells for a contaminated fractured bedrock aquifer in southeastern Pennsylvania. Groundwater in the vicinity of the North Penn Area 7 Superfund site, Montgomery County, Pennsylvania, was found to be contaminated with organic compounds, such as trichloroethylene (TCE), in 1979. At the time contamination was discovered, groundwater from the underlying fractured bedrock (shale) aquifer was the main source of supply for public drinking water and industrial use. As part of technical support to the U.S. Environmental Protection Agency (EPA) during the Remedial Investigation of the North Penn Area 7 Superfund site from 2000 to 2005, the U.S. Geological Survey (USGS) developed a model of regional groundwater flow to describe changes in groundwater flow and contaminant directions as a result of changes in pumping. Subsequently, large decreases in TCE concentrations (as much as 400 micrograms per liter) were measured in groundwater samples collected by the EPA from selected wells in 2010 compared to 2005‒06 concentrations.To provide insight on the fate of potentially contaminated groundwater during the period of generally decreasing pumping rates from 1990 to 2010, steady-state simulations were run using the previously developed groundwater-flow model for two conditions prior to extensive remediation, 1990 and 2000, two conditions subsequent to some remediation 2005 and 2010, and a No Pumping case, representing pre-development or cessation of pumping conditions. The model was used to (1) quantify the amount of recharge, including potentially contaminated recharge from sources near the land surface, that discharged to wells or streams and (2) delineate the areas contributing recharge that discharged to wells or streams for the five conditions.In all simulations, groundwater divides differed from surface-water divides, partly because of differences in stream elevations and because of geologic structure and pumping. In the 1990 and 2000 simulations, all recharge in and near the vicinity of North Penn Area 7 discharged to wells, but in the 2005 and 2010 simulations some recharge in this area discharged to streams, indicating possible discharge of contaminated groundwater from North Penn Area 7 sources to streams. As the amount of groundwater withdrawals by wells has declined since 1990, the area contributing recharge to wells in the vicinity of North Penn Area 7 has decreased.To determine the effect of changes in pumping on flow paths and possible flow-path-related contributions to the observed changes in spatial distribution of contaminants in groundwater from 2005 to 2010, the USGS conducted simulations using the previously developed regional groundwater-flow model using reported pumping and estimated recharge rates for 2005 and 2010. Flow paths from recharge at known contaminant source areas to discharge locations at wells or streams were simulated under steady-state conditions for the two periods. Simulated groundwater-flow paths shifted only slightly from 2005 to 2010 as a result of changes in pumping rates. These slight changes in groundwater-flow paths from known sources of contamination are not coincident with the spatial distribution of observed changes in TCE concentrations from 2005 to 2010, indicating that the decreases of TCE concentrations may be a result of other processes, such as source removal or degradation. Results of the simulations and the absence of increases in TCE-degradation-product concentrations indicate that the decreases of TCE concentrations observed in 2010 may be at least partly related to contaminant-source removal by soil excavation completed in 2005, although additional data would be needed to confirm this preliminary explanation.

  14. The Graded Alluvial River: Variable Flow and the Dominant Discharge

    NASA Astrophysics Data System (ADS)

    Blom, A.; Arkesteijn, L.; Viparelli, E.

    2016-12-01

    We derive analytical formulations for the graded or equilibrium longitudinal profile of a mixed-sediment alluvial river under variable flow. The formulations are applicable to reaches upstream from the backwater zone. The model is based on the conservation equations for the mass of two distinct sediment modes, sand and gravel, at the bed surface to account for the effects of grain size selective transport and abrasion of gravel particles. The effects of a variable flow rate are included by (a) treating the flow as a continuously changing yet steady water discharge (i.e. here termed an alternating steady discharge) and (b) assuming the time scale of changes in channel slope and bed surface texture to be much larger than the one of changes in flow rate. The equations are simplified realizing that at equilibrium the river profile finds itself in a dynamic steady state with oscillations around constant mean values of channel slope and bed surface texture. A generalized sediment transport relation representing the stochastic nature of sediment transport allows for explicit or analytical solutions to the streamwise decrease of both the channel slope and the bed surface mean grain size under variable flow for reaches unaffected by backwater effects. This modelling approach also provides a definition of a channel-forming or dominant water discharge, i.e., that steady water discharge that is equivalent in its effect on the equilibrium channel slope to the full hydrograph.

  15. Changes in jaw muscle activity and the physical properties of foods with different textures during chewing behaviors.

    PubMed

    Iguchi, Hiroko; Magara, Jin; Nakamura, Yuki; Tsujimura, Takanori; Ito, Kayoko; Inoue, Makoto

    2015-12-01

    This study aimed to investigate how the activity of the masseter (Mas) and suprahyoid (Hyoid) muscles is influenced by the physical properties of food, how changes in the rheological properties of food differ between different foods during the process of food reduction, and how different salivary flow rates affect bolus-making capability during masticatory behavior in healthy humans. Ten healthy adults participated in this study. Electromyographic (EMG) recordings were obtained from the Mas and Hyoid muscles, and 15 g of steamed rice and rice cake was prepared as test foods. In the ingestion test, the subjects were asked to eat each food in their usual manner. The chewing duration, number of chewing cycles before the first swallow, Mas and Hyoid EMG activity, and chewing cycle time were compared between the foods. Total chewing duration was divided into three substages: early, middle, and late; chewing cycle time and EMG activity per chewing cycle of each substage were compared between the foods and among the substages. In the spitting test, the rheological properties of the bolus at the end of each substage were compared between the foods and among the substages. Finally, stimulated salivary flow rates were measured and the relationships between salivary flow rate and chewing duration, EMG activity, and changes in physical food characteristics were investigated. There were significant differences in total chewing duration and the number of chewing cycles, but not in chewing cycle time, between the foods, which had similar hardness values. The EMG activity levels of the Mas and Hyoid per chewing cycle for the rice cake were significantly greater than for the steamed rice throughout the recording periods. While Mas activity did not change among the substages during chewing, Hyoid EMG activity decreased as chewing progressed. Chewing cycle time also gradually decreased as chewing progressed. The hardness of both foods initially increased, then gradually decreased back to baseline. The adhesiveness of the rice cake initially increased, and did not fall throughout the recording period; the adhesiveness of the steamed rice did not significantly change. Cohesiveness barely changed in either of the two foods during chewing, but was significantly greater for the rice cake than for the steamed rice. Finally, a correlation between the stimulated salivary flow rate and chewing performance was evident only in a change in Mas EMG activity. The current results demonstrate that the activities of the Mas and Hyoid muscles changed as chewing progressed, and were affected by hardness, adhesiveness, and cohesiveness. Salivary flow rate may affect the changes in Mas activity during the process of bolus formation. Copyright © 2015 Elsevier Inc. All rights reserved.

  16. Acute effects of electromagnetic stimulation of the brain on cortical activity, cortical blood flow, blood pressure and heart rate in the cat: an evaluation of safety.

    PubMed Central

    Eyre, J A; Flecknell, P A; Kenyon, B R; Koh, T H; Miller, S

    1990-01-01

    The influence of repeated high intensity electromagnetic stimulation of the brain on cortical activity, cortical blood flow, blood pressure and heart rate has been investigated in the cat, to evaluate the safety of the method. The observations have been made in preparations under propofol anaesthesia before, during and after periods of anoxia. Electromagnetic stimulation of the brain evoked activity in descending motor pathways and was recorded by activity in the median nerve and by muscle twitches. Following repeated series of high intensity stimulation there were no systematic changes in somatosensory evoked potentials or background EEG, nor were there signs of epileptogenic activity during electromagnetic stimulation, before, during or after periods of anoxia. No systematic changes in cortical blood flow, blood pressure or heart rate were observed during electromagnetic stimulation, before or after periods of anoxia. In conclusion, no acute adverse consequences following electromagnetic stimulation in the normal and anoxic cat brain were demonstrated. PMID:2380732

  17. Momentum rate probe for use with two-phase flows

    NASA Astrophysics Data System (ADS)

    Bush, S. G.; Bennett, J. B.; Sojka, P. E.; Panchagnula, M. V.; Plesniak, M. W.

    1996-05-01

    An instrument for measuring the momentum rate of two-phase flows is described, and design and construction details are provided. The device utilizes a conelike body to turn the flow from the axial to the radial direction. The force resulting from the change in momentum rate of the turning flow is measured using a strain-gage-instrumented cantilevered beam. The instrument is applicable to a wide range of flows including nuclear reactor coolant streams, refrigerants in heating-ventilating air-conditioning equipment, impingement cooling of small scale electronic hardware (computer chips are one example), supercritical fuel injection (in Diesel engines, for instance), and consumer product sprays (such as hair-care product sprays produced using effervescent atomizers). The latter application is discussed here. Features of the instrument include sensitivity to a wide range of forces and the ability to damp oscillations of the deflection cone. Instrument sensitivity allows measurement of momentum rates considerably lower (below 0.01 N) than those that could be obtained using previous devices. This feature is a direct result of our use of precision strain gages, capable of sensing strains below 20 μm/m, and the damping of oscillations which can overwhelm the force measurements. Oscillation damping results from a viscous fluid damper whose resistance is easily varied by changing fluids. Data used to calibrate the instrument are presented to demonstrate the effectiveness of the technique. As an example of the instrument's utility, momentum rate data obtained using it will be valuable in efforts to explain entrainment of surrounding air into effervescent atomizer-produced sprays and also to model the effervescent atomization process.

  18. Cyclic variation of ultrasonic backscattering from porcine whole blood under pulsatile flow

    NASA Astrophysics Data System (ADS)

    Lin, Yu-Hong

    1997-10-01

    The cyclic variation of ultrasonic backscattering from blood under pulsatile flow is believed to be related to the change of aggregation state of red cells and is only observed in whole blood. This study was to investigate the phenomenon by an invasive approach which was performed by inserting a 10 MHz catheter mounted transducer into a vessel. For ultrasonic measurement from blood, the most fundamental scheme is the hematocrit dependence. The backscatter maximum location was changed as the blood was stirred or stationary, as well as under steady laminar or turbulent flows. The same trend was also observed under pulsatile flow with 10% to 50% hematocrits in this study, as the backscattering to hematocrit curves were plotted at different times during a flow cycle. When the cyclic variation at 20 beats per minute (BPM) was interpreted in time domain, the enhanced aggregation at the beginning of shearing was observed. At 20 BPM with 40% hematocrit, the amplitude of cyclic variation was reduced when the shear rate was increased and the threshold of 150 s-1 was estimated. The results showed that there was no cyclic variation at 60 BPM. The backscattering was also plotted against the mean flow velocity, which demonstrated the hysteresis loops. The ultrasonic measurements showed that the relationship between the forward and backward paths of the loops were altered as beat rate, hematocrit, and shear rate were varied. Since the pulsatile flow was very complicated, a computational fluid dynamics package, FIDAPTM, was used to compute the shear rate based on the Power Law Model for non-Newtonian fluid viscosity. The non- Newtonian index and consistency in the model were computed from the viscosity to shear rate curves at 10% to 50% hematocrits measured by a cone-plate viscometer. For in vivo measurements, small pigs were used as models. Ultrasonic backscattering measurements were performed in the arteries and veins. The effect of stenosis was also investigated at the site below the renal branch in the artery. The results show that the cyclic variation from whole blood was mediated by the shear rate, hematocrit, beat rate, and fibrinogen concentration.

  19. Hydrogeologic investigations of the Sierra Vista subwatershed of the Upper San Pedro Basin, Cochise County, southeast Arizona

    USGS Publications Warehouse

    Pool, Donald R.; Coes, Alissa L.

    1999-01-01

    The hydrogeologic system in the Sierra Vista subwatershed of the Upper San Pedro Basin in southeastern Arizona was investigated for the purpose of developing a better understanding of stream-aquifer interactions. The San Pedro River is an intermittent stream that supports a narrow corridor of riparian vegetation. Withdrawal of ground water will result in reduced discharge from the basin through reduced base flow and evapotranspiration; however, the rate and location of reduced discharge are uncertain. The investigation resulted in better definition of distributions of silt and clay in the regional aquifer; changes in seasonal precipitation, runoff, and base flow in the San Pedro River; sources of base flow; and regional water-level changes. Regional ground-water flow is separated into deep-confined and shallow-unconfined systems by silt and clay. Precipitation, runoff, and base flow declined at the Charleston streamflow-gaging station from 1936 through 1997 for the months of June through October. Base flow at the Charleston station during 1996 and 1997 was primarily supplied by ground water recharged near the San Pedro River during recent major runoff and by minor contributions from the regional aquifer. The decline in base flow, about 2 cubic feet per second, has several probable causes including declining runoff and recharge near the river during June through October and increased interception of ground-water flow to the river by wells and phreatophytes. Water levels in wells throughout the regional aquifer generally declined at rates of 0.2 to 0.5 feet per year between 1940 and the mid-1980's, which corresponded with a period of below-average winter precipitation. Water levels in wells in the Fort Huachuca and Sierra Vista areas declined at rates that were faster than regional rates of decline through 1998 and caused diversion of ground-water flow that would have discharged along perennial stream reaches.

  20. Tracking lava flow emplacement on the east rift zone of Kilauea, Hawai'i with InSAR coherence

    NASA Astrophysics Data System (ADS)

    Dietterich, H. R.; Schmidt, D. A.; Poland, M. P.; Cashman, K. V.

    2010-12-01

    Remote sensing of lava flows from the Pu`u `O`o-Kupaianaha eruption on the east rift zone of Kilauea serves to document the ongoing eruption, while yielding insights into how lava flow fields develop. InSAR is widely used to measure deformation by detecting minute changes in ground surfaces that stay correlated during repeat observations. The eruption and emplacement of fresh lava on the surface, however, disrupts the coherence of the radar echoes, allowing the area of these flows to be mapped with InSAR coherence images. We use InSAR correlation to visualize surface flow activity from 2003-2010 in order to quantify eruption rates and explore lava flow behavior from emplacement onward. This method for mapping flows does not require daylight, cloudless skies, or access to the active flow fields that is necessary for traditional visual surveys. We produce coherence maps for hundreds of 35 to 105-day periods from twelve tracks of ENVISAT SAR data using the GAMMA software package. By combining these coherence maps we create a unique dataset with which to develop this technique and amass lava flow observations. Where correlation images overlap in time, they are summed and normalized to derive a time series of surface coherence with a spatial resolution of 20 meters and a temporal resolution of as little as a few days. We identify existing stable flows by their high radar coherence, and determine a coherence threshold that is applied to each correlation image. This threshold is calibrated so as to reduce the effects of varying baseline, time duration, and atmospheric effects between images, as well as decorrelation due to vegetation. The final images illustrate lava flow activity that corresponds well with surface flow outlines and tube locations recorded by the USGS mapping effort. The InSAR-derived results serve to enhance these traditional maps by documenting pixel-scale changes over time. When compared with forward looking infrared (FLIR) thermal imagery, pixel decorrelation can be related to specific styles of activity, including surface breakouts or deformation, where field examination is difficult. We analyze these detailed snapshots of the flows to derive estimates of flow parameters, including effusion rates, lava flow areas and volumes, and surface lava flow activity over time, which provides a means of examining controls on flow paths, advance rates, and morphologies. We find that once emplaced, flows remain decorrelated for months before becoming correlated again in a piecewise fashion, suggesting that correlation rate may be dependent on thickness and cooling rate. As the eruption continues, this ever-expanding dataset has great potential for remotely capturing quantitative data from an active flow field and improving our knowledge of lava flows and their hazards.

  1. Absence of arterial baroreflex modulation of skin sympathetic activity and sweat rate during whole-body heating in humans

    NASA Technical Reports Server (NTRS)

    Wilson, T. E.; Cui, J.; Crandall, C. G.

    2001-01-01

    1. Prior findings suggest that baroreflexes are capable of modulating skin blood flow, but the effects of baroreceptor loading/unloading on sweating are less clear. Therefore, this project tested the hypothesis that pharmacologically induced alterations in arterial blood pressure in heated humans would lead to baroreflex-mediated changes in both skin sympathetic nerve activity (SSNA) and sweat rate. 2. In seven subjects mean arterial blood pressure was lowered (approximately 8 mmHg) and then raised (approximately 13 mmHg) by bolus injections of sodium nitroprusside and phenylephrine, respectively. Moreover, in a separate protocol, arterial blood pressure was reduced via steady-state administration of sodium nitroprusside. In both normothermia and heat-stress conditions the following responses were monitored: sublingual and mean skin temperatures, heart rate, beat-by-beat blood pressure, skin blood flow (laser-Doppler flowmetry), local sweat rate and SSNA (microneurography from peroneal nerve). 3. Whole-body heating increased skin and sublingual temperatures, heart rate, cutaneous blood flow, sweat rate and SSNA, but did not change arterial blood pressure. Heart rate was significantly elevated (from 74 +/- 3 to 92 +/- 4 beats x min(-1); P < 0.001) during bolus sodium nitroprusside-induced reductions in blood pressure, and significantly reduced (from 92 +/- 4 to 68 +/- 4 beats x min(-1); P < 0.001) during bolus phenylephrine-induced elevations in blood pressure, thereby demonstrating normal baroreflex function in these subjects. 4. Neither SSNA nor sweat rate was altered by rapid (bolus infusion) or sustained (steady-state infusion) changes in blood pressure regardless of the thermal condition. 5. These data suggest that SSNA and sweat rate are not modulated by arterial baroreflexes in normothermic or moderately heated individuals.

  2. Users' guide to system dynamics model describing Coho salmon survival in Olema Creek, Point Reyes National Seashore, Marin County, California

    USGS Publications Warehouse

    Woodward, Andrea; Torregrosa, Alicia; Madej, Mary Ann; Reichmuth, Michael; Fong, Darren

    2014-01-01

    The system dynamics model described in this report is the result of a collaboration between U.S. Geological Survey (USGS) scientists and National Park Service (NPS) San Francisco Bay Area Network (SFAN) staff, whose goal was to develop a methodology to integrate inventory and monitoring data to better understand ecosystem dynamics and trends using salmon in Olema Creek, Marin County, California, as an example case. The SFAN began monitoring multiple life stages of coho salmon (Oncorhynchus kisutch) in Olema Creek during 2003 (Carlisle and others, 2013), building on previous monitoring of spawning fish and redds. They initiated water-quality and habitat monitoring, and had access to flow and weather data from other sources. This system dynamics model of the freshwater portion of the coho salmon life cycle in Olema Creek integrated 8 years of existing monitoring data, literature values, and expert opinion to investigate potential factors limiting survival and production, identify data gaps, and improve monitoring and restoration prescriptions. A system dynamics model is particularly effective when (1) data are insufficient in time series length and/or measured parameters for a statistical or mechanistic model, and (2) the model must be easily accessible by users who are not modelers. These characteristics helped us meet the following overarching goals for this model: Summarize and synthesize NPS monitoring data with data and information from other sources to describe factors and processes affecting freshwater survival of coho salmon in Olema Creek. Provide a model that can be easily manipulated to experiment with alternative values of model parameters and novel scenarios of environmental drivers. Although the model describes the ecological dynamics of Olema Creek, these dynamics are structurally similar to numerous other coastal streams along the California coast that also contain anadromous fish populations. The model developed for Olema can be used, at least as a starting point, for other watersheds. This report describes each of the model elements with sufficient detail to guide the primary target audience, the NPS resource specialist, to run the model, interpret the results, change the input data to explore hypotheses, and ultimately modify and improve the model. Running the model and interpreting the results does not require modeling expertise on the part of the user. Additional companion publications will highlight other aspects of the model, such as its development, the rationale behind the methodological approach, scenario testing, and discussions of its use. System dynamics models consist of three basic elements: stocks, flows, and converters. Stocks are measurable quantities that can change over time, such as animal populations. Flows are any processes or conditions that change the quantity in a stock over time (Ford, 1999), are expressed in the model as a rate of change, and are diagrammed as arrows to or from stocks. Converters are processes or conditions that change the rate of flows. A converter is connected to a flow with an arrow indicating that it alters the rate of change. Anything that influences the rate of change (such as different environmental conditions, other external factors, or feedbacks from other stocks or flows) is modeled as a converter. For example, the number of fish in a population is appropriately modeled as a stock. Mortality is modeled as a flow because it is a rate of change over time used to determine the number of fish in the population. The density-dependent effect on mortality is modeled as a converter because it influences the rate of morality. Together, the flow and converter change the number, or stock, of juvenile coho. The instructions embedded in the stocks, flows, converters, and the sequence in which they are linked are processed by the simulation software with each completed sequence composing a model run. At each modeled time step within the model run, the stock counts will go up, down, or stay the same based on the modeled flows and the influence of converters on those flows. The model includes a user-friendly interface to change model parameters, which allows park staff and others to conduct sensitivity analyses, incorporate future knowledge, and implement scenarios for various future conditions. The model structure incorporates place holders for relationships that we hypothesize are significant but data are currently lacking. Future climate scenarios project stream temperatures higher than any that have ever been recorded at Olema Creek. Exploring climate change impacts on coho survival is a high priority for park staff, therefore the model provides the user with the option to experiment with hypothesized effects and to incorporate effects based on future observations.

  3. Shape optimized headers and methods of manufacture thereof

    DOEpatents

    Perrin, Ian James

    2013-11-05

    Disclosed herein is a shape optimized header comprising a shell that is operative for collecting a fluid; wherein an internal diameter and/or a wall thickness of the shell vary with a change in pressure and/or a change in a fluid flow rate in the shell; and tubes; wherein the tubes are in communication with the shell and are operative to transfer fluid into the shell. Disclosed herein is a method comprising fixedly attaching tubes to a shell; wherein the shell is operative for collecting a fluid; wherein an internal diameter and/or a wall thickness of the shell vary with a change in pressure and/or a change in a fluid flow rate in the shell; and wherein the tubes are in communication with the shell and are operative to transfer fluid into the shell.

  4. Surfactant effects on interfacial flow and thermal transport processes during phase change in film boiling

    NASA Astrophysics Data System (ADS)

    Premnath, Kannan N.; Hajabdollahi, Farzaneh; Welch, Samuel W. J.

    2018-04-01

    The presence of surfactants in two-phase flows results in the transport and adsorption of surfactants to the interface, and the resulting local interfacial concentration significantly influences the surface tension between the liquid and vapor phases in a fluid undergoing phase change. This computational study is aimed at understanding and elucidating the mechanisms of enhanced flows and thermal transport processes in film boiling due to the addition of surfactants. A change in surface tension results in a change in the critical Rayleigh-Taylor wavelength leading to different bubble release patterns and a change in the overall heat transfer rates. Due to the presence of surfactants, an additional transport mechanism of the Marangoni convection arises from the resulting tangential gradients in the surfactant concentration along the phase interface. Our computational approach to study such phenomena consists of representing the interfacial motion by means of the coupled level set-volume-of-fluid method, the fluid motion via the classical marker-and-cell approach, as well as representations for the bulk transport of energy and surfactants, in conjunction with a phase change model and an interfacial surfactant model. Using such an approach, we perform numerical simulations of surfactant-laden single mode as well as multiple mode film boiling and study the effect of surfactants on the transport processes in film boiling, including bubble release patterns, vapor generation rates, and heat transfer rates at different surfactant concentrations. The details of the underlying mechanisms will be investigated and interpreted.

  5. A simple depth-averaged model for dry granular flow

    NASA Astrophysics Data System (ADS)

    Hung, Chi-Yao; Stark, Colin P.; Capart, Herve

    Granular flow over an erodible bed is an important phenomenon in both industrial and geophysical settings. Here we develop a depth-averaged theory for dry erosive flows using balance equations for mass, momentum and (crucially) kinetic energy. We assume a linearized GDR-Midi rheology for granular deformation and Coulomb friction along the sidewalls. The theory predicts the kinematic behavior of channelized flows under a variety of conditions, which we test in two sets of experiments: (1) a linear chute, where abrupt changes in tilt drive unsteady uniform flows; (2) a rotating drum, to explore steady non-uniform flow. The theoretical predictions match the experimental results well in all cases, without the need to tune parameters or invoke an ad hoc equation for entrainment at the base of the flow. Here we focus on the drum problem. A dimensionless rotation rate (related to Froude number) characterizes flow geometry and accounts not just for spin rate, drum radius and gravity, but also for grain size, wall friction and channel width. By incorporating Coriolis force the theory can treat behavior under centrifuge-induced enhanced gravity. We identify asymptotic flow regimes at low and high dimensionless rotation rates that exhibit distinct power-law scaling behaviors.

  6. Deep brain stimulation reveals emotional impact processing in ventromedial prefrontal cortex.

    PubMed

    Gjedde, Albert; Geday, Jacob

    2009-12-07

    We tested the hypothesis that modulation of monoaminergic tone with deep-brain stimulation (DBS) of subthalamic nucleus would reveal a site of reactivity in the ventromedial prefrontal cortex that we previously identified by modulating serotonergic and noradrenergic mechanisms by blocking serotonin-noradrenaline reuptake sites. We tested the hypothesis in patients with Parkinson's disease in whom we had measured the changes of blood flow everywhere in the brain associated with the deep brain stimulation of the subthalamic nucleus. We determined the emotional reactivity of the patients as the average impact of emotive images rated by the patients off the DBS. We then searched for sites in the brain that had significant correlation of the changes of blood flow with the emotional impact rated by the patients. The results indicate a significant link between the emotional impact when patients are not stimulated and the change of blood flow associated with the DBS. In subjects with a low emotional impact, activity measured as blood flow rose when the electrode was turned on, while in subjects of high impact, the activity at this site in the ventromedial prefrontal cortex declined when the electrode was turned on. We conclude that changes of neurotransmission in the ventromedial prefrontal cortex had an effect on the tissue that depends on changes of monoamine concentration interacting with specific combinations of inhibitory and excitatory monoamine receptors.

  7. Characterizing pressure issues due to turbulent flow in tubing, in ultra-fast chiral supercritical fluid chromatography at up to 580bar.

    PubMed

    Berger, Terry A

    2016-12-02

    It has been widely suggested that the outlet pressure be changed to maintain constant density ("isopycnic" conditions) when comparing the kinetic performance of different columns in supercritical fluid chromatography (SFC). However, at high flow rates, flow in the tubing is turbulent, causing large extra-column pressure drops that limit options for changing outlet pressure. Some of these pressure drops occur before and some after the column, obscuring the actual column inlet and outlet pressures. In this work, a 4.6×100mm, 1.8μm R,R-Whelk-O1 column was used with low dispersion LD (120μm) plumbing to generate sub-1min chiral separations. However, the optimum, or near optimum, flow rate was 5mL-min -1 , producing a system pressure of 580bar (with 40% methanol, outlet pressure 120bar). Both the flow rate and pump pressure required were near the limits of the instrument, and significantly exceeded the capability of many other SFC's. Extra-column pressure drops (ΔP ec ) were as high as 200bar, caused mostly by turbulent flow in the tubing. The ΔP ec increased by more than the square of the flow rate. Reynolds Numbers (Re) were calculated for tubing as a function of flow rate between 100 and 400bar and 5-20% methanol in CO 2 , and 40°-60°C. This represents the most extensive analysis of turbulence in tubing in the SFC literature. Flow in 120μm ID tubing was calculated to be laminar below 1.0mL-min -1 , mostly transitional up to 2.5mL-min -1 and virtually always turbulent at 3mL-min -1 and higher. Flow in 170μm tubing is turbulent at lower flows but generates half the ΔP ec due to the lower mobile phase linear velocity. The results suggest that, while sub-minute chromatograms are easily generated, 4.6mm columns are not very user friendly for use with sub-2μm packings. The high flow rates required just to reach optimum result in high ΔP ec generated by the tubing, causing uncertainty in the true column inlet, outlet, and average column pressure/density. When comparing kinetic performance of columns with different dimensions, the pressure drops in the tubing must be considered. Copyright © 2016 Elsevier B.V. All rights reserved.

  8. Relationship between unstimulated salivary flow rate and saliva composition of healthy children in Taiwan.

    PubMed

    Wu, Katie P; Ke, Jyh-Yuh; Chung, Chia-Ying; Chen, Chia-Ling; Hwang, Tsong-Long; Chou, Ming-Yen; Wong, Alice M K; Hu, Ching-Fang; Lee, Yu-Cheng

    2008-01-01

    Saliva is one of the most important factors in regulating oral health, with flow rate and composition changing throughout development and during disease. In view of the shortage of data, the present study aimed to shed light on the relationship between unstimulated salivary flow rate and saliva composition of healthy children in Taiwan. Forty-four normal, healthy children from 3-14 years of age were divided into three age groups: pre-school, elementary school and junior-high school. All participants received salivary flow rate, pH and saliva composition analysis under unstimulated conditions. One-way ANOVA and Pearson's correlation were used. Statistical significance was set at p < 0.05. Our results suggest that, under unstimulated conditions, the salivary flow rate of the elementary school group was greater than that of the pre-school group (p < 0.05). No difference in pH was found among the three groups. Intergroup salivary calcium, phosphorus and amylase did not reach statistical difference. As the flow rate increased, the pH increased (r = 0.364, p < 0.05) but the protein level decreased (r = -0.473, p < 0.05). In addition, salivary protein was positively correlated to age (r = 0.479, p < 0.05) and negatively correlated to pH (r = -0.361, p < 0.01). Age-related increase in the unstimulated salivary flow rate of pre-school and elementary school groups was noted. As the flow rate increased, the pH increased but the protein level decreased. The information obtained may serve as reference values for the growing interest in saliva as a diagnostic tool, especially monitoring those with neurological or oral motor dysfunction.

  9. Moving beyond the limits of mass transport in liquid absorbent microfilms through the implementation of surface-induced vortices

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bigham, S; Yu, DZ; Chugh, D

    2014-02-01

    The slow diffusion of an absorbate molecule into an absorbent often makes the absorption process a rate-limiting step in many applications. In cases involving an absorbate with a high heat of phase change, such as water absorption into a LiBr (lithium bromide) solution, the absorption rate is further slowed due to significant heating of the absorbent. Recently, it has been demonstrated that constraining a LiBr solution film by a hydrophobic porous structure enables manipulation of the solution flow thermohydraulic characteristics. Here, it is shown that mass transport mode in a constrained laminar solution flow can be changed from diffusive tomore » advective. This change in mode is accomplished through stretching and folding the laminar streamlines within the solution film via the implementation of micro-scale features on the flow channel surface. The process induces vortices within the solution film, which continuously bring concentrated solution from the bottom and middle of the solution channel to its interface with the vapor phase, thus leading to a significant enhancement in the absorption rate. The detailed physics of the involved transport processes is elucidated using the LBM (Lattice Boltzmann Method). Published by Elsevier Ltd.« less

  10. Characterization of the relationship between ceramic pot filter water production and turbidity in source water.

    PubMed

    Salvinelli, Carlo; Elmore, A Curt; Reidmeyer, Mary R; Drake, K David; Ahmad, Khaldoun I

    2016-11-01

    Ceramic pot filters represent a common and effective household water treatment technology in developing countries, but factors impacting water production rate are not well-known. Turbidity of source water may be principal indicator in characterizing the filter's lifetime in terms of water production capacity. A flow rate study was conducted by creating four controlled scenarios with different turbidities, and influent and effluent water samples were tested for total suspended solids and particle size distribution. A relationship between average flow rate and turbidity was identified with a negative linear trend of 50 mLh -1 /NTU. Also, a positive linear relationship was found between the initial flow rate of the filters and average flow rate calculated over the 23 day life of the experiment. Therefore, it was possible to establish a method to estimate the average flow rate given the initial flow rate and the turbidity in the influent water source, and to back calculate the maximum average turbidity that would need to be maintained in order to achieve a specific average flow rate. However, long-term investigations should be conducted to assess how these relationships change over the expected CPF lifetime. CPFs rejected fine suspended particles (below 75 μm), especially particles with diameters between 0.375 μm and 10 μm. The results confirmed that ceramic pot filters are able to effectively reduce turbidity, but pretreatment of influent water should be performed to avoid premature failure. Copyright © 2016 Elsevier Ltd. All rights reserved.

  11. Two phase flow bifurcation due to turbulence: transition from slugs to bubbles

    NASA Astrophysics Data System (ADS)

    Górski, Grzegorz; Litak, Grzegorz; Mosdorf, Romuald; Rysak, Andrzej

    2015-09-01

    The bifurcation of slugs to bubbles within two-phase flow patterns in a minichannel is analyzed. The two-phase flow (water-air) occurring in a circular horizontal minichannel with a diameter of 1 mm is examined. The sequences of light transmission time series recorded by laser-phototransistor sensor is analyzed using recurrence plots and recurrence quantification analysis. Recurrence parameters allow the two-phase flow patterns to be found. On changing the water flow rate we identified partitioning of slugs or aggregation of bubbles.

  12. Determination of deployment specific chemical uptake rates for SDB-RPD Empore disk using a passive flow monitor (PFM).

    PubMed

    O'Brien, Dominique; Bartkow, Michael; Mueller, Jochen F

    2011-05-01

    The use of the adsorbent styrenedivinylbenzene-reverse phase sulfonated (SDB-RPD) Empore disk in a chemcatcher type passive sampler is routinely applied in Australia when monitoring herbicides in aquatic environments. One key challenge in the use of passive samplers is mitigating the potentially confounding effects of varying flow conditions on chemical uptake by the passive sampler. Performance reference compounds (PRCs) may be applied to correct sampling rates (R(s)) for site specific changed in flow and temperature however evidence suggests the use of PRCs is unreliable when applied to adsorbent passive samplers. The use of the passive flow monitor (PFM) has been introduced for the assessment of site-specific changes in water flow. In the presented study we have demonstrated that the R(s) at which both atrazine and prometryn are accumulated within the SDB-RPD-Empore disk is dependent on the flow conditions. Further, the calibration of the measured R(s) for chemical uptake by the SDB-RPD-Empore disk to the mass lost from the PFM has shown that the PFM provides an accurate measure of R(s) for flow velocities from 0 to 16cms(-1). Notably, for flow rates >16cms(-1), a non linear increase in the R(s) of both herbicides was observed which indicates that the key resistance to uptake into the SDB-RPD Empore disk is associated with the diffusion through the overlying diffusion limiting membrane. Overall the greatest uncertainty remains at very low flow conditions, which are unlikely to often occur in surface waters. Validation of the PFM use has also been undertaken in a limited field study. Copyright © 2011 Elsevier Ltd. All rights reserved.

  13. Robust estimates of environmental effects on population vital rates: an integrated capture–recapture model of seasonal brook trout growth, survival and movement in a stream network

    USGS Publications Warehouse

    Letcher, Benjamin H.; Schueller, Paul; Bassar, Ronald D.; Nislow, Keith H.; Coombs, Jason A.; Sakrejda, Krzysztof; Morrissey, Michael; Sigourney, Douglas B.; Whiteley, Andrew R.; O'Donnell, Matthew J.; Dubreuil, Todd L.

    2015-01-01

    Modelling the effects of environmental change on populations is a key challenge for ecologists, particularly as the pace of change increases. Currently, modelling efforts are limited by difficulties in establishing robust relationships between environmental drivers and population responses.We developed an integrated capture–recapture state-space model to estimate the effects of two key environmental drivers (stream flow and temperature) on demographic rates (body growth, movement and survival) using a long-term (11 years), high-resolution (individually tagged, sampled seasonally) data set of brook trout (Salvelinus fontinalis) from four sites in a stream network. Our integrated model provides an effective context within which to estimate environmental driver effects because it takes full advantage of data by estimating (latent) state values for missing observations, because it propagates uncertainty among model components and because it accounts for the major demographic rates and interactions that contribute to annual survival.We found that stream flow and temperature had strong effects on brook trout demography. Some effects, such as reduction in survival associated with low stream flow and high temperature during the summer season, were consistent across sites and age classes, suggesting that they may serve as robust indicators of vulnerability to environmental change. Other survival effects varied across ages, sites and seasons, indicating that flow and temperature may not be the primary drivers of survival in those cases. Flow and temperature also affected body growth rates; these responses were consistent across sites but differed dramatically between age classes and seasons. Finally, we found that tributary and mainstem sites responded differently to variation in flow and temperature.Annual survival (combination of survival and body growth across seasons) was insensitive to body growth and was most sensitive to flow (positive) and temperature (negative) in the summer and fall.These observations, combined with our ability to estimate the occurrence, magnitude and direction of fish movement between these habitat types, indicated that heterogeneity in response may provide a mechanism providing potential resilience to environmental change. Given that the challenges we faced in our study are likely to be common to many intensive data sets, the integrated modelling approach could be generally applicable and useful.

  14. Robust estimates of environmental effects on population vital rates: an integrated capture-recapture model of seasonal brook trout growth, survival and movement in a stream network.

    PubMed

    Letcher, Benjamin H; Schueller, Paul; Bassar, Ronald D; Nislow, Keith H; Coombs, Jason A; Sakrejda, Krzysztof; Morrissey, Michael; Sigourney, Douglas B; Whiteley, Andrew R; O'Donnell, Matthew J; Dubreuil, Todd L

    2015-03-01

    Modelling the effects of environmental change on populations is a key challenge for ecologists, particularly as the pace of change increases. Currently, modelling efforts are limited by difficulties in establishing robust relationships between environmental drivers and population responses. We developed an integrated capture-recapture state-space model to estimate the effects of two key environmental drivers (stream flow and temperature) on demographic rates (body growth, movement and survival) using a long-term (11 years), high-resolution (individually tagged, sampled seasonally) data set of brook trout (Salvelinus fontinalis) from four sites in a stream network. Our integrated model provides an effective context within which to estimate environmental driver effects because it takes full advantage of data by estimating (latent) state values for missing observations, because it propagates uncertainty among model components and because it accounts for the major demographic rates and interactions that contribute to annual survival. We found that stream flow and temperature had strong effects on brook trout demography. Some effects, such as reduction in survival associated with low stream flow and high temperature during the summer season, were consistent across sites and age classes, suggesting that they may serve as robust indicators of vulnerability to environmental change. Other survival effects varied across ages, sites and seasons, indicating that flow and temperature may not be the primary drivers of survival in those cases. Flow and temperature also affected body growth rates; these responses were consistent across sites but differed dramatically between age classes and seasons. Finally, we found that tributary and mainstem sites responded differently to variation in flow and temperature. Annual survival (combination of survival and body growth across seasons) was insensitive to body growth and was most sensitive to flow (positive) and temperature (negative) in the summer and fall. These observations, combined with our ability to estimate the occurrence, magnitude and direction of fish movement between these habitat types, indicated that heterogeneity in response may provide a mechanism providing potential resilience to environmental change. Given that the challenges we faced in our study are likely to be common to many intensive data sets, the integrated modelling approach could be generally applicable and useful. Published 2014. This article is a U.S. Government work and is in the public domain in the USA.

  15. The Influence of Slope Breaks on Lava Flow Surface Disruption

    NASA Technical Reports Server (NTRS)

    Glaze, Lori S.; Baloga, Stephen M.; Fagents, Sarah A.; Wright, Robert

    2014-01-01

    Changes in the underlying slope of a lava flow impart a significant fraction of rotational energy beyond the slope break. The eddies, circulation and vortices caused by this rotational energy can disrupt the flow surface, having a significant impact on heat loss and thus the distance the flow can travel. A basic mechanics model is used to compute the rotational energy caused by a slope change. The gain in rotational energy is deposited into an eddy of radius R whose energy is dissipated as it travels downstream. A model of eddy friction with the ambient lava is used to compute the time-rate of energy dissipation. The key parameter of the dissipation rate is shown to be rho R(sup 2/)mu, where ? is the lava density and mu is the viscosity, which can vary by orders of magnitude for different flows. The potential spatial disruption of the lava flow surface is investigated by introducing steady-state models for the main flow beyond the steepening slope break. One model applies to slow-moving flows with both gravity and pressure as the driving forces. The other model applies to fast-moving, low-viscosity, turbulent flows. These models provide the flow velocity that establishes the downstream transport distance of disrupting eddies before they dissipate. The potential influence of slope breaks is discussed in connection with field studies of lava flows from the 1801 Hualalai and 1823 Keaiwa Kilauea, Hawaii, and 2004 Etna eruptions.

  16. Changes in cardiac output and tibial artery flow during and after progressive LBNP

    NASA Technical Reports Server (NTRS)

    1980-01-01

    A 3.0 MHz Pulsed Doppler velocity meter (PD) was used to determine blood velocities in the ascending aorta from the suprasternal notch before, during and after progressive 5 min stages of lower body negative pressure (LBNP) in 7 subjects. Changes in stroke volume were calculated from the systolic velocity integrals. A unique 20 MHz PD was used to estimate bloodflow in the posterior tibial artery. With -20 torr mean stroke volume fell 11% and then continued to decline by 48% before LBNP was terminated. Mean tibial flow fell progressively with LBNP stress, due to an increase in reverse flow component and a reduction in peak forward flow and diameter. Stroke volume increased and heart rate fell dramatically during the first 15 sec of recovery. The LBNP was terminated early in 2 subjects because of vasovagal symptons (V). During V the stroke volume rose 86% which more than compensated for the drop in heart rate. This implies that V is accompanied by a paradoxical increase in venous return and that the reduction in HR is the primary cardiovascular event. During the first 15 sec of recovery these 2 subjects had a distinctive marked rise to heart rate reminiscent of the Bainbridge reflex.

  17. Improving the desulfurization performance of CaCO3 with sodium humate

    NASA Astrophysics Data System (ADS)

    Feng, Run; Sun, Zhiguo; Zhang, Wenqing; Huang, Hao; Hu, Haihang; Zhang, Li; Xie, Hongyong

    2018-02-01

    The influence of these factors on desulphurization efficiency was studied by changing the amount of calcium carbonate, the concentration of sulfur dioxide, the liquid flow rate of absorbent and the air flow rate, the optimum working condition was determined by the research of limestone-gypsum desulphurization process commonly used in industry. By changing the amount of calcium carbonate, we conclude that the volume of water in the desulfurization efficiency does not increase with the adding amount of calcium carbonate. The optimum conditions were determined : at the condicion of the concentration of 500ppm of sulfur dioxide, 10g calcium carbonate, 150L/h liquid flow and the minimum air flow rate of 6.75m3/h, the highest desulfurization efficiency was close to 100% when sodium humate was not added, but the holding time was only about 5 minutes. After adding 3g of humic acid, the desulfurization efficiency was improved obviously, and the instantaneous efficiency of 100% lasting for about 40 minutes. It can be seen that, calcium carbonate in the addition of humic acid sodium can significantly improve the absorption of calcium carbonate performance of SO2.

  18. Causes of distal volcano-tectonic seismicity inferred from hydrothermal modeling

    NASA Astrophysics Data System (ADS)

    Coulon, C. A.; Hsieh, P. A.; White, R.; Lowenstern, J. B.; Ingebritsen, S. E.

    2017-10-01

    Distal volcano-tectonic (dVT) seismicity typically precedes eruption at long-dormant volcanoes by days to years. Precursory dVT seismicity may reflect magma-induced fluid-pressure pulses that intersect critically stressed faults. We explored this hypothesis using an open-source magmatic-hydrothermal code that simulates multiphase fluid and heat transport over the temperature range 0 to 1200 °C. We calculated fluid-pressure changes caused by a small (0.04 km3) intrusion and explored the effects of flow geometry (channelized vs. radial flow), magma devolatilization rates (0-15 kg/s), and intrusion depths (5 and 7.5 km, above and below the brittle-ductile transition). Magma and host-rock permeabilities were key controlling parameters and we tested a wide range of permeability (k) and permeability anisotropies (kh/kv), including k constant, k(z), k(T), and k(z, T, P) distributions, examining a total of 1600 realizations to explore the relevant parameter space. Propagation of potentially causal pressure changes (ΔP ≥ 0.1 bars) to the mean dVT location (6 km lateral distance, 6 km depth) was favored by channelized fluid flow, high devolatilization rates, and permeabilities similar to those found in geothermal reservoirs (k 10- 16 to 10- 13 m2). For channelized flow, magma-induced thermal pressurization alone can generate cases of Δ P ≥ 0.1 bars for all permeabilities in the range 10- 16 to 10- 13 m2, whereas in radial flow regimes thermal pressurization causes Δ P < 0.1 bars for all permeabilities. Changes in distal fluid pressure occurred before proximal pressure changes given modest anisotropies (kh/kv 10-100). Invoking k(z,T,P) and high, sustained devolatilization rates caused large dynamic fluctuations in k and P in the near-magma environment but had little effect on pressure changes at the distal dVT location. Intrusion below the brittle-ductile transition damps but does not prevent pressure transmission to the dVT site.

  19. Use of pressure in reversed-phase liquid chromatography to study protein conformational changes by differential deuterium exchange.

    PubMed

    Makarov, Alexey A; Schafer, Wes A; Helmy, Roy

    2015-02-17

    The market of protein therapeutics is exploding, and characterization methods for proteins are being further developed to understand and explore conformational structures with regards to function and activity. There are several spectroscopic techniques that allow for analyzing protein secondary structure in solution. However, a majority of these techniques need to use purified protein, concentrated enough in the solution to produce a relevant spectrum. In this study, we describe a novel approach which uses ultrahigh pressure liquid chromatography (UHPLC) coupled with mass-spectrometry (MS) to explore compressibility of the secondary structure of proteins under increasing pressure detected by hydrogen-deuterium exchange (HDX). Several model proteins were used for these studies. The studies were conducted with UHPLC in isocratic mode at constant flow rate and temperature. The pressure was modified by a backpressure regulator up to about 1200 bar. It was found that the increase of retention factors upon pressure increase, at constant flow rate and temperature, was based on reduction of the proteins' molecular molar volume. The change in the proteins' molecular molar volume was caused by changes in protein folding, as was revealed by differential deuterium exchange. The degree of protein folding under certain UHPLC conditions can be controlled by pressure, at constant temperature and flow rate. By modifying pressure during UHPLC separation, it was possible to achieve changes in protein folding, which were manifested as changes in the number of labile protons exchanged to deuterons, or vice versa. Moreover, it was demonstrated with bovine insulin that a small difference in the number of protons exchanged to deuterons (based on protein folding under pressure) could be observed between batches obtained from different sources. The use of HDX during UHPLC separation allowed one to examine protein folding by pressure at constant flow rate and temperature in a mixture of sample solution with minimal amounts of sample used for analysis.

  20. Characteristic Analysis and Experiment of a Dynamic Flow Balance Valve

    NASA Astrophysics Data System (ADS)

    Bin, Li; Song, Guo; Xuyao, Mao; Chao, Wu; Deman, Zhang; Jin, Shang; Yinshui, Liu

    2017-12-01

    Comprehensive characteristics of a dynamic flow balance valve of water system were analysed. The flow balance valve can change the drag efficient automatically according to the condition of system, and the effective control flowrate is constant in the range of job pressure. The structure of the flow balance valve was introduced, and the theoretical calculation formula for the variable opening of the valve core was derived. A rated pressure of 20kPa to 200kPa and a rated flowrate of 10m3/h were offered in the numerical work. Static and fluent CFX analyses show good behaviours: through the valve core structure optimization and improve design of the compressive spring, the dynamic flow balance valve can stabilize the flowrate of system evidently. And experiments show that the flow control accuracy is within 5%.

  1. Modeling of Gallium Nitride Hydride Vapor Phase Epitaxy

    NASA Technical Reports Server (NTRS)

    Meyyappan, Meyya; Arnold, James O. (Technical Monitor)

    1997-01-01

    A reactor model for the hydride vapor phase epitaxy of GaN is presented. The governing flow, energy, and species conservation equations are solved in two dimensions to examine the growth characteristics as a function of process variables and reactor geometry. The growth rate varies with GaCl composition but independent of NH3 and H2 flow rates. A change in carrier gas for Ga source from H2 to N2 affects the growth rate and uniformity for a fixed reactor configuration. The model predictions are in general agreement with observed experimental behavior.

  2. A study of the role of renal nerves in the renal responses to 60° head-up tilt in the anaesthetized dog

    PubMed Central

    DiBona, G. F.; Johns, E. J.

    1980-01-01

    1. Renal responses to 10 min of 60° head-up tilt were measured in anaesthetized dogs in which renal perfusion pressure was maintained at a relatively constant value. 2. Tilting was associated with a fall in systemic blood pressure and an increase in heart rate. Renal blood flow and glomerular filtration rate remained constant while there was a significant decrease in both absolute and fractional excretion of sodium. 3. Animals which had undergone acute renal denervation were tilted. The cardiovascular responses were similar to intact animals. A fall in renal blood flow was observed but the glomerular filtration rate was maintained at a steady value during tilting. The decreased renal tubular excretion of sodium measured in intact animals was abolished. 4. Alpha-adrenergic blockade of the kidney was achieved by infusion of phentolamine into the renal artery. Tilting of these animals caused cardiovascular changes similar to those observed in control animals but renal blood flow, glomerular filtration rate and sodium handling remained unchanged. 5. Animals in which both carotid sinuses had been acutely denervated were tilted. Systemic blood pressure fell as in intact animals, but the rise in heart rate was significantly less. Renal blood flow, glomerular filtration rate and the rate of sodium excretion were unchanged. 6. A 10 min period of 60° head-up tilt in anaesthetized dogs resulted in an unchanged renal blood flow and glomerular filtration rate which was associated with a decrease in both fractional excretion of sodium and sodium excretion. The renal sympathetic nerves were shown to be responsible for these changes in tubular sodium handling which appeared to exert their action via renal tubular α-adrenergic receptors. This activation of the renal nerves appeared to be mediated by the carotid sinus baroreceptor reflex. PMID:7381761

  3. CO2-vegetation feedbacks and other climate changes implicated in reducing base flow

    NASA Astrophysics Data System (ADS)

    Trancoso, Ralph; Larsen, Joshua R.; McVicar, Tim R.; Phinn, Stuart R.; McAlpine, Clive A.

    2017-03-01

    Changes in the hydrological cycle have a significant impact in water limited environments. Globally, some of these regions are experiencing declining precipitation yet are simultaneously becoming greener, partly due to vegetation feedbacks associated with increasing atmospheric CO2 concentrations. Reduced precipitation together with increasing rates of actual evapotranspiration diminishes streamflow, especially base flow, a critical freshwater dry-season resource. Here we assess recent changes in base flow in Australia from 1981-2013 and 1950-2013 and separate the contribution of precipitation, potential evapotranspiration, and other factors on base flow trends. Our findings reveal that these other factors influencing the base flow trends are best explained by an increase in photosynthetic activity. These results provide the first robust observational evidence that increasing atmospheric CO2 and its associated vegetation feedbacks are reducing base flow in addition to other climatic impacts. These findings have broad implications for water resource management, especially in the world's water limited regions.

  4. Control of fluid flow during Bridgman crystal growth using low-frequency vibrational stirring

    NASA Astrophysics Data System (ADS)

    Zawilski, Kevin Thomas

    The goal of this research program was to develop an in depth understanding of a promising new method for stirring crystal growth melts called coupled vibrational stirring (CVS). CVS is a mixing technique that can be used in sealed systems and produces rapid mixing through vortex flows. Under normal operating conditions, CVS uses low-frequency vibrations to move the growth crucible along a circular path, producing a surface wave and convection in the melt. This research focused on the application of CVS to the vertical Bridgman technique. CVS generated flows were directly studied using a physical modeling system containing water/glycerin solutions. Sodium nitrate was chosen as a model growth system because the growth process could be directly observed using a transparent furnace. Lead magnesium niobate-lead titanate (PMNT) was chosen as the third system because of its potential application for high performance solid state transducers and actuators. In this study, the critical parameters for controlling CVS flows in cylindrical Bridgman systems were established. One of the most important results obtained was the dependence of an axial velocity gradient on the vibrational frequency. By changing the frequency, the intensity of fluid flow at a given depth can be easily manipulated. The intensity of CVS flows near the crystal-melt interface was found to be important. When flow intensity near the interface increased during growth, large growth rate fluctuations and significant changes in interface shape were observed. To eliminate such fluctuations, a constant flow rate near the crystal-melt interface was maintained by decreasing the vibrational frequency. A continuous frequency ramp was found to be essential to grow crystals of good quality under strong CVS flows. CVS generated flows were also useful in controlling the shape of the growth interface. In the sodium nitrate system without stirring, high growth rates produced a very concave interface. By adjusting the flow intensity near the interface, CVS flows were able to flatten the growth interface under these extreme growth conditions.

  5. Quantifying Hydrate Formation in Gas-rich Environments Using the Method of Characteristics

    NASA Astrophysics Data System (ADS)

    You, K.; Flemings, P. B.; DiCarlo, D. A.

    2015-12-01

    Methane hydrates hold a vast amount of methane globally, and have huge energy potential. Methane hydrates in gas-rich environments are the most promising production targets. We develop a one-dimensional analytical solution based on the method of characteristics to explore hydrate formation in such environments (Figure 1). Our solution shows that hydrate saturation is constant with time and space in a homogeneous system. Hydrate saturation is controlled by the initial thermodynamic condition of the system, and changed by the gas fractional flow. Hydrate saturation increases with the initial distance from the hydrate phase boundary. Different gas fractional flows behind the hydrate solidification front lead to different gas saturations at the hydrate solidification front. The higher the gas saturation at the front, the less the volume available to be filled by hydrate, and hence the lower the hydrate saturation. The gas fractional flow depends on the relative permeability curves, and the forces that drive the flow. Viscous forces (the drive for flow induced from liquid pressure gradient) dominate the flow, and hydrate saturation is independent on the gas supply rates and the flow directions at high gas supply rates. Hydrate saturation can be estimated as one minus the ratio of the initial to equilibrium salinity. Gravity forces (the drive for flow induced from the gravity) dominate the flow, and hydrate saturation depends on the flow rates and the flow directions at low gas supply rates. Hydrate saturation is highest for upward flow, and lowest for downward flow. Hydrate saturation decreases with the flow rate for upward flow, and increases with the flow rate for downward flow. This analytical solution illuminates how hydrate is formed by gas (methane, CO2, ethane, propane) flowing into brine-saturated sediments at both the laboratory and geological scales (Figure 1). It provides an approach to generalize the understanding of hydrate solidification in gas-rich environments, although complicated numerical models have been developed previously. Examples of gas expulsion into hydrate stability zones and the associated hydrate formation in both laboratory and geological scales, and CO2 sequestration into CO2-hydrates near the seafloor and under the permafrost will be presented.

  6. Comparison of Series of Vugs and Non-vuggy Synthetic Porous Media on Formation Damage

    NASA Astrophysics Data System (ADS)

    Khan, H.; DiCarlo, D. A.; Prodanovic, M.

    2017-12-01

    Produced water reinjection (PWRI) is an established cost-effective oil field practice where produced water is injected without any cleanup, for water flooding or disposal. Resultantly the cost of fresh injection fluid and/or processing produced water is saved. A common problem with injection of unprocessed water is formation damage in the near injection zone due to solids (fines) entrapment, causing a reduction in permeability and porosity of the reservoir. Most studies have used homogeneous porous media with unimodal grain sizes, while real world porous media often has a wide range of pores, up to and including vugs in carbonaceous rocks. Here we fabricate a series of vugs in synthetic porous media by sintering glass beads with large dissolvable inclusions. The process is found to be repeatable, allowing a similar vug configuration to be tested for different flow conditions. Bi-modal glass bead particles (25 & 100 micron) are injected at two different flow rates and three different injection concentrations. Porosity, permeability and effluent concentration are determined using CT scanning, pressure measurements and particle counting (Coulter counter), respectively. Image analysis is performed on the CT images to determine the change in vug size for each flow condition. We find that for the same flow conditions, heterogeneous media with series of vugs have an equal or greater permeability loss compared to homogeneous porous media. A significant change in permeability is observed at the highest concentration and flow rate as more particles approach the filter quickly, resulting in a greater loss in permeability in the lower end of the core. Image analysis shows the highest loss in vug size occurs at the low flow rate and highest concentration. The lower vug is completely blocked for this flow case. For all flow cases lower values of porosity are observed after the core floods. At low flow rate and medium concentration, a drastic loss in porosity is observed in the lower part of the core, after the vuggy zone. This trough is also distinctly clear in the homogeneous core for the same flow conditions. This study focuses on understanding the effect of pore heterogeneity on formation damage. We conclude that more damage is done deeper in vuggy formations at high flow rates, resulting in shorter injection cycle prior to clean up.

  7. Development of a new IHA method for impact assessment of climate change on flow regime

    NASA Astrophysics Data System (ADS)

    Yang, Tao; Cui, Tong; Xu, Chong-Yu; Ciais, Philippe; Shi, Pengfei

    2017-09-01

    The Indicators of Hydrologic Alteration (IHA) based on 33 parameters in five dimensions (flow magnitude, timing, duration, frequency and change rate) have been widely used in evaluation of hydrologic alteration in river systems. Yet, inter-correlation seriously exists amongst those parameters, therefore constantly underestimates or overestimates actual hydrological changes. Toward the end, a new method (Representative-IHA, RIHA) is developed by removing repetitions based on Criteria Importance Through Intercriteria Correlation (CRITIC) algorithm. RIHA is testified in evaluating effects of future climate change on hydro-ecology in the Niger River of Africa. Future flows are projected using three watershed hydrological models forced by five general circulation models (GCMs) under three Representative Concentration Pathways (RCPs) scenarios. Results show that: (1) RIHA is able to eliminate self-correlations amongst IHA indicators and identify the dominant characteristics of hydrological alteration in the Upper Niger River, (2) March streamflow, September streamflow, December streamflow, 30-day annual maximum, low pluses duration and fall rates tends to increase over the period 2010-2099, while July streamflow and 90-day annual minimum streamflow shows decrease, (3) the Niger River will undergo moderate flow alteration under RCP8.5 in 2050s and 2080s and low alteration other scenarios, (4) future flow alteration may induce increase water temperatures, reduction dissolved oxygen and food resources. Consequently, aquatic biodiversity and fish community of Upper Niger River would become more vulnerable in the future. The new method enables more scientific evaluation for multi-dimensional hydrologic alteration under the context of climate change.

  8. The Effect of modeled recharge distribution on simulated groundwater availability and capture

    USGS Publications Warehouse

    Tillman, Fred D.; Pool, Donald R.; Leake, Stanley A.

    2015-01-01

    Simulating groundwater flow in basin-fill aquifers of the semiarid southwestern United States commonly requires decisions about how to distribute aquifer recharge. Precipitation can recharge basin-fill aquifers by direct infiltration and transport through faults and fractures in the high-elevation areas, by flowing overland through high-elevation areas to infiltrate at basin-fill margins along mountain fronts, by flowing overland to infiltrate along ephemeral channels that often traverse basins in the area, or by some combination of these processes. The importance of accurately simulating recharge distributions is a current topic of discussion among hydrologists and water managers in the region, but no comparative study has been performed to analyze the effects of different recharge distributions on groundwater simulations. This study investigates the importance of the distribution of aquifer recharge in simulating regional groundwater flow in basin-fill aquifers by calibrating a groundwater-flow model to four different recharge distributions, all with the same total amount of recharge. Similarities are seen in results from steady-state models for optimized hydraulic conductivity values, fit of simulated to observed hydraulic heads, and composite scaled sensitivities of conductivity parameter zones. Transient simulations with hypothetical storage properties and pumping rates produce similar capture rates and storage change results, but differences are noted in the rate of drawdown at some well locations owing to the differences in optimized hydraulic conductivity. Depending on whether the purpose of the groundwater model is to simulate changes in groundwater levels or changes in storage and capture, the distribution of aquifer recharge may or may not be of primary importance.

  9. Multi-metric calibration of hydrological model to capture overall flow regimes

    NASA Astrophysics Data System (ADS)

    Zhang, Yongyong; Shao, Quanxi; Zhang, Shifeng; Zhai, Xiaoyan; She, Dunxian

    2016-08-01

    Flow regimes (e.g., magnitude, frequency, variation, duration, timing and rating of change) play a critical role in water supply and flood control, environmental processes, as well as biodiversity and life history patterns in the aquatic ecosystem. The traditional flow magnitude-oriented calibration of hydrological model was usually inadequate to well capture all the characteristics of observed flow regimes. In this study, we simulated multiple flow regime metrics simultaneously by coupling a distributed hydrological model with an equally weighted multi-objective optimization algorithm. Two headwater watersheds in the arid Hexi Corridor were selected for the case study. Sixteen metrics were selected as optimization objectives, which could represent the major characteristics of flow regimes. Model performance was compared with that of the single objective calibration. Results showed that most metrics were better simulated by the multi-objective approach than those of the single objective calibration, especially the low and high flow magnitudes, frequency and variation, duration, maximum flow timing and rating. However, the model performance of middle flow magnitude was not significantly improved because this metric was usually well captured by single objective calibration. The timing of minimum flow was poorly predicted by both the multi-metric and single calibrations due to the uncertainties in model structure and input data. The sensitive parameter values of the hydrological model changed remarkably and the simulated hydrological processes by the multi-metric calibration became more reliable, because more flow characteristics were considered. The study is expected to provide more detailed flow information by hydrological simulation for the integrated water resources management, and to improve the simulation performances of overall flow regimes.

  10. An automated cell analysis sensing system based on a microfabricated rheoscope for the study of red blood cells physiology.

    PubMed

    Bransky, Avishay; Korin, Natanel; Nemirovski, Yael; Dinnar, Uri

    2006-08-15

    An automated rheoscope has been developed, utilizing a microfabricated glass flow cell, high speed camera and advanced image-processing software. RBCs suspended in a high viscosity medium were filmed flowing through a microchannel. Under these conditions, RBCs exhibit different orientations and deformations according to their location in the velocity profile. The rheoscope system produces valuable data such as velocity profile of RBCs, spatial distribution within a microchannel and deformation index (DI) curves. The variation of DI across the channel height, due to change in shear stress, was measured carrying implications for diffractometry methods. These curves of DI were taken at a constant flow rate and cover most of the relevant shear stress spectrum. This is an improvement of the existing techniques for deformability measurements and may serve as a diagnostic tool for certain blood disorders. The DI curves were compared to measurements of the flowing RBCs velocity profile. In addition, we found that RBCs flowing in a microchannel are mostly gathered in the center of the flow and maintain a characteristic spatial distribution. The spatial distribution in this region changes slightly with increasing flow rate. Hence, the system described, provides means for examining the behavior of individual RBCs, and may serve as a microfabricated diagnostic device for deformability measurement.

  11. Experimental study on burning rates of square/rectangular gasoline and methanol pool fires under longitudinal air flow in a wind tunnel.

    PubMed

    Hu, L H; Liu, S; Peng, W; Huo, R

    2009-09-30

    Square pool fires with length of 5, 7.5, 10, 15, 20, 25 and 30 cm and rectangular pool fires with dimensions of 10 cm x 20 cm and 10 cm x 40 cm were burned in a wind tunnel, under a longitudinal air flow ranged from 0 to 3m/s with incremental change of about 0.5m/s. Methanol and gasoline were burned and compared, with results indicated that their burning rates showed different response to the longitudinal air flow. With the increase of the longitudinal air flow speed, the burning rates of methanol pool fires, except the 5 cm square one, first decreased and then increased, but those of the 5 cm methanol square one and the gasoline pool fires increased monotonously. The burning rate of smaller square pool fires increased more significantly than that of the larger ones, as well as the enlargement of their flame attachment length along the ground. The burning rate of a rectangular pool fire with longer rim parallel to the longitudinal flow increased faster, but the flame attachment length seemed to increase more gradually, with the increase of the longitudinal air flow speed than that perpendicular to.

  12. Estuarine Response to River Flow and Sea-Level Rise under Future Climate Change and Human Development

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yang, Zhaoqing; Wang, Taiping; Voisin, Nathalie

    Understanding the response of river flow and estuarine hydrodynamics to climate change, land-use/land-cover change (LULC), and sea-level rise is essential to managing water resources and stress on living organisms under these changing conditions. This paper presents a modeling study using a watershed hydrology model and an estuarine hydrodynamic model, in a one-way coupling, to investigate the estuarine hydrodynamic response to sea-level rise and change in river flow due to the effect of future climate and LULC changes in the Snohomish River estuary, Washington, USA. A set of hydrodynamic variables, including salinity intrusion points, average water depth, and salinity of themore » inundated area, were used to quantify the estuarine response to river flow and sea-level rise. Model results suggest that salinity intrusion points in the Snohomish River estuary and the average salinity of the inundated areas are a nonlinear function of river flow, although the average water depth in the inundated area is approximately linear with river flow. Future climate changes will shift salinity intrusion points further upstream under low flow conditions and further downstream under high flow conditions. In contrast, under the future LULC change scenario, the salinity intrusion point will shift downstream under both low and high flow conditions, compared to present conditions. The model results also suggest that the average water depth in the inundated areas increases linearly with sea-level rise but at a slower rate, and the average salinity in the inundated areas increases linearly with sea-level rise; however, the response of salinity intrusion points in the river to sea-level rise is strongly nonlinear.« less

  13. Long-term changes in river system hydrology in Texas

    NASA Astrophysics Data System (ADS)

    Zhang, Yiwen; Wurbs, Ralph

    2018-06-01

    Climate change and human actives are recognized as a topical issue that change long-term water budget, flow-frequency, and storage-frequency characteristics of different river systems. Texas is characterized by extreme hydrologic variability both spatially and temporally. Meanwhile, population and economic growth and accompanying water resources development projects have greatly impacted river flows throughout Texas. The relative effects of climate change, water resources development, water use, and other factors on long-term changes in river flow, reservoir storage, evaporation, water use, and other components of the water budgets of different river basins of Texas have been simulated in this research using the monthly version of the Water Rights Analysis Package (WRAP) modelling system with input databases sets from the Texas Commission on Environmental Quality (TCEQ) and Texas Water Development Board (TWDB). The results show that long-term changes are minimal from analysis monthly precipitation depths. Evaporation rates vary greatly seasonally and for much of the state appear to have a gradually upward trend. River/reservoir system water budgets and river flow characteristics have changed significantly during the past 75 years in response to water resources development and use.

  14. Enhancement of Arterial Pressure Pulsatility by Controlling Continuous-Flow Left Ventricular Assist Device Flow Rate in Mock Circulatory System.

    PubMed

    Bozkurt, Selim; van de Vosse, Frans N; Rutten, Marcel C M

    Continuous-flow left ventricular assist devices (CF-LVADs) generally operate at a constant speed, which reduces pulsatility in the arteries and may lead to complications such as functional changes in the vascular system, gastrointestinal bleeding, or both. The purpose of this study is to increase the arterial pulse pressure and pulsatility by controlling the CF-LVAD flow rate. A MicroMed DeBakey pump was used as the CF-LVAD. A model simulating the flow rate through the aortic valve was used as a reference model to drive the pump. A mock circulation containing two synchronized servomotor-operated piston pumps acting as left and right ventricles was used as a circulatory system. Proportional-integral control was used as the control method. First, the CF-LVAD was operated at a constant speed. With pulsatile-speed CF-LVAD assistance, the pump was driven such that the same mean pump output was generated. Continuous and pulsatile-speed CF-LVAD assistance provided the same mean arterial pressure and flow rate, while the index of pulsatility increased significantly for both arterial pressure and pump flow rate signals under pulsatile speed pump support. This study shows the possibility of improving the pulsatility of CF-LVAD support by regulating pump speed over a cardiac cycle without reducing the overall level of support.

  15. Transition regime analytical solution to gas mass flow rate in a rectangular micro channel

    NASA Astrophysics Data System (ADS)

    Dadzie, S. Kokou; Dongari, Nishanth

    2012-11-01

    We present an analytical model predicting the experimentally observed gas mass flow rate in rectangular micro channels over slip and transition regimes without the use of any fitting parameter. Previously, Sone reported a class of pure continuum regime flows that requires terms of Burnett order in constitutive equations of shear stress to be predicted appropriately. The corrective terms to the conventional Navier-Stokes equation were named the ghost effect. We demonstrate in this paper similarity between Sone ghost effect model and newly so-called 'volume diffusion hydrodynamic model'. A generic analytical solution to gas mass flow rate in a rectangular micro channel is then obtained. It is shown that the volume diffusion hydrodynamics allows to accurately predict the gas mass flow rate up to Knudsen number of 5. This can be achieved without necessitating the use of adjustable parameters in boundary conditions or parametric scaling laws for constitutive relations. The present model predicts the non-linear variation of pressure profile along the axial direction and also captures the change in curvature with increase in rarefaction.

  16. Microfluidic generation of aqueous two-phase system (ATPS) droplets by controlled pulsating inlet pressures.

    PubMed

    Moon, Byeong-Ui; Jones, Steven G; Hwang, Dae Kun; Tsai, Scott S H

    2015-06-07

    We present a technique that generates droplets using ultralow interfacial tension aqueous two-phase systems (ATPS). Our method combines a classical microfluidic flow focusing geometry with precisely controlled pulsating inlet pressure, to form monodisperse ATPS droplets. The dextran (DEX) disperse phase enters through the central inlet with variable on-off pressure cycles controlled by a pneumatic solenoid valve. The continuous phase polyethylene glycol (PEG) solution enters the flow focusing junction through the cross channels at a fixed flow rate. The on-off cycles of the applied pressure, combined with the fixed flow rate cross flow, make it possible for the ATPS jet to break up into droplets. We observe different droplet formation regimes with changes in the applied pressure magnitude and timing, and the continuous phase flow rate. We also develop a scaling model to predict the size of the generated droplets, and the experimental results show a good quantitative agreement with our scaling model. Additionally, we demonstrate the potential for scaling-up of the droplet production rate, with a simultaneous two-droplet generating geometry. We anticipate that this simple and precise approach to making ATPS droplets will find utility in biological applications where the all-biocompatibility of ATPS is desirable.

  17. The Influence of Insulin Dependent Diabetes Mellitus on Dental Caries and Salivary Flow

    PubMed Central

    Gupta, V. K.; Malhotra, Seema; Sharma, Vasuda; Hiremath, S. S.

    2014-01-01

    Objective. To assess whether or not there was any change in the dental caries and rate of salivary flow of patients with Insulin Dependent Diabetes Mellitus (IDDM) and the contribution of salivary flow to caries risk in IDDM. Setting. Department of Endocrinology, MS Ramaiah Hospital, Bangalore, India. Design. A comparative cross-sectional descriptive type. Materials and Methods. The sample consisted of two groups: 140 diabetic group (mean age 14.8 yr) and 140 nondiabetic group (mean age 13.7 yr). Dental caries by dmf(t) and dmf(s) indices for primary dentition and DMF(T) and DMF(S) indices was used in permanent dentition to assess the dental caries experience. Both stimulated and unstimulated salivary flow rate were assessed after collection of saliva. Results. In diabetic group 76% had carious lesion and in nondiabetic group 85.3% had carious lesion. Diabetics have lower mean DMFT, DMFS, dmft, and dmfs compared to the nondiabetic group. Diminished unstimulated and stimulated salivary flow rate in diabetic than nondiabetic group. Conclusions. The findings obtained conclude that even though there was reduced salivary flow rate in diabetic group the caries prevalence was low. PMID:26464864

  18. The Influence of Insulin Dependent Diabetes Mellitus on Dental Caries and Salivary Flow.

    PubMed

    Gupta, V K; Malhotra, Seema; Sharma, Vasuda; Hiremath, S S

    2014-01-01

    Objective. To assess whether or not there was any change in the dental caries and rate of salivary flow of patients with Insulin Dependent Diabetes Mellitus (IDDM) and the contribution of salivary flow to caries risk in IDDM. Setting. Department of Endocrinology, MS Ramaiah Hospital, Bangalore, India. Design. A comparative cross-sectional descriptive type. Materials and Methods. The sample consisted of two groups: 140 diabetic group (mean age 14.8 yr) and 140 nondiabetic group (mean age 13.7 yr). Dental caries by dmf(t) and dmf(s) indices for primary dentition and DMF(T) and DMF(S) indices was used in permanent dentition to assess the dental caries experience. Both stimulated and unstimulated salivary flow rate were assessed after collection of saliva. Results. In diabetic group 76% had carious lesion and in nondiabetic group 85.3% had carious lesion. Diabetics have lower mean DMFT, DMFS, dmft, and dmfs compared to the nondiabetic group. Diminished unstimulated and stimulated salivary flow rate in diabetic than nondiabetic group. Conclusions. The findings obtained conclude that even though there was reduced salivary flow rate in diabetic group the caries prevalence was low.

  19. The selective use of functional optical variables in the control of forward speed

    NASA Technical Reports Server (NTRS)

    Johnson, Walter W.; Awe, Cynthia A.

    1994-01-01

    Previous work on the perception and control of simulated vehicle speed has examined the contributions of optical flow rate (angular visual speed) and texture, or edge rate (frequency of passing terrain objects or markings) on the perception and control of forward speed. However, these studies have not examined the ability to selectively use edge rate or flow rate. The two studies presented here show that this ability is far greater for pilots than non-pilots, as would be expected since pilots must control vehicular speed over a variety of altitudes where flow rates change independently of forward speed. These studies also show that this ability to selectively use these variables is linked to the visual contextual information about the relative validity (linkage with speed) of the two variables. Subjective judgment data also indicated that awareness of altitude and ground texture density did not mediate ground speed awareness.

  20. Radial blanket assembly orificing arrangement

    DOEpatents

    Patterson, J.F.

    1975-07-01

    A nuclear reactor core for a liquid metal cooled fast breeder reactor is described in which means are provided for increasing the coolant flow through the reactor fuel assemblies as the reactor ages by varying the coolant flow rate with the changing coolant requirements during the core operating lifetime. (auth)

  1. Development of Long-Lifetime Pulsed Gas Valves for Pulsed Electric Thrusters

    NASA Technical Reports Server (NTRS)

    Burkhardt, Wendel M.; Crapuchettes, John M.; Addona, Brad M.; Polzin, Kurt A.

    2015-01-01

    The design and test results for two types of pulsed gas valves are presented. The valves, a piezo valve and a solenoid actuated valve, must have exceedingly long lifetime to support gas-fed pulsed electric thruster operation for missions of interest. The performance of both valves was tested, with both demonstrating the capability to throttle the gas flow rate while maintaining low leakage levels below 10(exp -3) sccs of He at the beginning of valve lifetime. The piezo valve varies the flow rate by changing the amount that the valve is open, which is a function of applied voltage. This valve demonstrated continuous throttlability from 0-10 mL/s, with opening and closing times of 100 microsecond or less. The solenoid actuated valve flow rate changes as a function of the inlet gas pressure, with demonstrated flow rates in these tests from 2.7-11 mL per second. The valve response time is slower than the piezo valve, opening in 1-2 ms and closing in several ms. The solenoid actuated valve was tested to one million cycles, with the valve performance remaining relatively unchanged throughout the test. Galling of the sliding plunger caused the valve to bind and fail just after one million cycles, but at this point in the test the valve sealing surface leak rate still appeared to be well below the maximum target leak rake of 1×10(exp -3) sccs of He.

  2. Applications of ERTS-1 Data Collection System (DCS) in the Arizona Regional Ecological Test Site (ARETS). [water management, streamflow rates, flood control

    NASA Technical Reports Server (NTRS)

    Schumann, H. H. (Principal Investigator)

    1973-01-01

    The author has identified the following significant results. The DCS water-stage data from the USGS streamflow gaging station on the Verde River near Camp Verde furnished information sufficient for the accurate computation of daily mean streamflow rates during the first 2 months of operation. Daily mean flow rates computed from the DCS data agreed with those computed from the digital recorder data within + or - 5% during periods of stable or slowly changing flow and within + or - 10% during periods of rapidly changing high flow. The SRP was furnished near-real time DCS information on snow moisture content and streamflow rates for use in the management and operation of the multiple-use reservoir system. The SRP, by prudent water management and the use of near-real time hydrologic data furnished by microwave and ERTS DCS telemetry, was successful in anticipating the amount of flow into the Salt and Verde Rivers and in the subsequent release of water at rates that did not create flooding in metropolitan Phoenix. Only minor flooding occurred along the Gila River west of Phoenix. According to the Maricopa County Civil Defense agency, wage and salary losses of about $11,400,000 resulted from closing of roads across the Salt River in the winter and spring of 1972-73; however, the number and duration of the closing were minimized by use of DCS data.

  3. Human Autonomic and Cerebrovascular Responses to Inspiratory Impedance

    DTIC Science & Technology

    2006-06-01

    recorded the ECG, finger photoplethysmographic arterial pressure , cerebral blood flow velocity, and muscle sympathetic nerve activity (MSNA). In a... pressures and R-R intervals, or between arterial pres- sures and cerebral blood flow velocities at the LF (p > 0.05). Conclusions: Our results demonstrate...that the ITD increases arterial pressure , heart rate, and cerebral blood flow velocity independent of changes in autonomic car- diovascular control or

  4. Dynamic Pore-Scale Imaging of Reactive Transport in Heterogeneous Carbonates at Reservoir Conditions Across Multiple Dissolution Regimes

    NASA Astrophysics Data System (ADS)

    Menke, H. P.; Bijeljic, B.; Andrew, M. G.; Blunt, M. J.

    2014-12-01

    Sequestering carbon in deep geologic formations is one way of reducing anthropogenic CO2 emissions. When supercritical CO2 mixes with brine in a reservoir, the acid generated has the potential to dissolve the surrounding pore structure. However, the magnitude and type of dissolution are condition dependent. Understanding how small changes in the pore structure, chemistry, and flow properties affect dissolution is paramount for successful predictive modelling. Both 'Pink Beam' synchrotron radiation and a Micro-CT lab source are used in dynamic X-ray microtomography to investigate the pore structure changes during supercritical CO2 injection in carbonate rocks of varying heterogeneity at high temperatures and pressures and various flow-rates. Three carbonate rock types were studied, one with a homogeneous pore structure and two heterogeneous carbonates. All samples are practically pure calcium carbonate, but have widely varying rock structures. Flow-rate was varied in three successive experiments by over an order of magnitude whlie keeping all other experimental conditions constant. A 4-mm carbonate core was injected with CO2-saturated brine at 10 MPa and 50oC. Tomographic images were taken at 30-second to 20-minute time-resolutions during a 2 to 4-hour injection period. A pore network was extracted using a topological analysis of the pore space and pore-scale flow modelling was performed directly on the binarized images with connected pathways and used to track the altering velocity distributions. Significant differences in dissolution type and magnitude were found for each rock type and flowrate. At the highest flow-rates, the homogeneous carbonate was seen to have predominately uniform dissolution with minor dissolution rate differences between the pores and pore throats. Alternatively, the heterogeneous carbonates which formed wormholes at high flow rates. At low flow rates the homogeneous rock developed wormholes, while the heterogeneous samples showed evidence of compact dissolution. This study serves as a unique benchmark for pore-scale reactive transport modelling directly on the binarized Micro-CT images. Dynamic pore-scale imaging methods offer advantages in helping explain the dominant processes at the pore scale so that they may be up-scaled for accurate model prediction.

  5. LAV@HAZARD: a Web-GIS Framework for Real-Time Forecasting of Lava Flow Hazards

    NASA Astrophysics Data System (ADS)

    Del Negro, C.; Bilotta, G.; Cappello, A.; Ganci, G.; Herault, A.

    2014-12-01

    Crucial to lava flow hazard assessment is the development of tools for real-time prediction of flow paths, flow advance rates, and final flow lengths. Accurate prediction of flow paths and advance rates requires not only rapid assessment of eruption conditions (especially effusion rate) but also improved models of lava flow emplacement. Here we present the LAV@HAZARD web-GIS framework, which combines spaceborne remote sensing techniques and numerical simulations for real-time forecasting of lava flow hazards. By using satellite-derived discharge rates to drive a lava flow emplacement model, LAV@HAZARD allows timely definition of parameters and maps essential for hazard assessment, including the propagation time of lava flows and the maximum run-out distance. We take advantage of the flexibility of the HOTSAT thermal monitoring system to process satellite images coming from sensors with different spatial, temporal and spectral resolutions. HOTSAT was designed to ingest infrared satellite data acquired by the MODIS and SEVIRI sensors to output hot spot location, lava thermal flux and discharge rate. We use LAV@HAZARD to merge this output with the MAGFLOW physics-based model to simulate lava flow paths and to update, in a timely manner, flow simulations. Thus, any significant changes in lava discharge rate are included in the predictions. A significant benefit in terms of computational speed was obtained thanks to the parallel implementation of MAGFLOW on graphic processing units (GPUs). All this useful information has been gathered into the LAV@HAZARD platform which, due to the high degree of interactivity, allows generation of easily readable maps and a fast way to explore alternative scenarios. We will describe and demonstrate the operation of this framework using a variety of case studies pertaining to Mt Etna, Sicily. Although this study was conducted on Mt Etna, the approach used is designed to be applicable to other volcanic areas around the world.

  6. Can Wet Rocky Granular Flows Become Debris Flows Due to Fine Sediment Production by Abrasion?

    NASA Astrophysics Data System (ADS)

    Arabnia, O.; Sklar, L. S.; Bianchi, G.; Mclaughlin, M. K.

    2015-12-01

    Debris flows are rapid mass movements in which elevated pore pressures are sustained by a viscous fluid matrix with high concentrations of fine sediments. Debris flows may form from coarse-grained wet granular flows as fine sediments are entrained from hillslope and channel material. Here we investigate whether abrasion of the rocks within a granular flow can produce sufficient fine sediments to create debris flows. To test this hypothesis experimentally, we used a set of 4 rotating drums ranging from 0.2 to 4.0 m diameter. Each drum has vanes along the boundary ensure shearing within the flow. Shear rate was varied by changing drum rotational velocity to maintain a constant Froude Number across drums. Initial runs used angular clasts of granodiorite with a tensile strength of 7.6 MPa, with well-sorted coarse particle size distributions linearly scaled with drum radius. The fluid was initially clear water, which rapidly acquired fine-grained wear products. After each 250 m tangential distance, we measured the particle size distributions, and then returned all water and sediment to the drums for subsequent runs. We calculate particle wear rates using statistics of size and mass distributions, and by fitting the Sternberg equation to the rate of mass loss from the size fraction > 2mm. Abundant fine sediments were produced in the experiments, but very little change in the median grain size was detected. This appears to be due to clast rounding, as evidenced by a decrease in the number of stable equilibrium resting points. We find that the growth in the fine sediment concentration in the fluid scales with unit drum power. This relationship can be used to estimate fine sediment production rates in the field. We explore this approach at Inyo Creek, a steep catchment in the Sierra Nevada, California. There, a significant debris flow occurred in July 2013, which originated as a coarse-grained wet granular flow. We use surveys to estimate flow depth and velocity where super-elevation occurred, to calculate a unit power of 4.5 KW/m2. From this we predict that 14% of the coarse mass is converted to fine sediment by abrasion per km. At that rate, the increase in fines concentration may have been sufficient to cause a wet granular flow to evolve into a debris flow within the first 1 km of its > 4km travel distance.

  7. Reduction of Altitude Diffuser Jet Noise Using Water Injection

    NASA Technical Reports Server (NTRS)

    Allgood, Daniel C.; Saunders, Grady P.; Langford, Lester A.

    2014-01-01

    A feasibility study on the effects of injecting water into the exhaust plume of an altitude rocket diffuser for the purpose of reducing the far-field acoustic noise has been performed. Water injection design parameters such as axial placement, angle of injection, diameter of injectors, and mass flow rate of water have been systematically varied during the operation of a subscale altitude test facility. The changes in acoustic far-field noise were measured with an array of free-field microphones in order to quantify the effects of the water injection on overall sound pressure level spectra and directivity. The results showed significant reductions in noise levels were possible with optimum conditions corresponding to water injection at or just upstream of the exit plane of the diffuser. Increasing the angle and mass flow rate of water injection also showed improvements in noise reduction. However, a limit on the maximum water flow rate existed as too large of flow rate could result in un-starting the supersonic diffuser.

  8. Reduction of Altitude Diffuser Jet Noise Using Water Injection

    NASA Technical Reports Server (NTRS)

    Allgood, Daniel C.; Saunders, Grady P.; Langford, Lester A.

    2011-01-01

    A feasibility study on the effects of injecting water into the exhaust plume of an altitude rocket diffuser for the purpose of reducing the far-field acoustic noise has been performed. Water injection design parameters such as axial placement, angle of injection, diameter of injectors, and mass flow rate of water have been systematically varied during the operation of a subscale altitude test facility. The changes in acoustic far-field noise were measured with an array of free-field microphones in order to quantify the effects of the water injection on overall sound pressure level spectra and directivity. The results showed significant reductions in noise levels were possible with optimum conditions corresponding to water injection at or just upstream of the exit plane of the diffuser. Increasing the angle and mass flow rate of water injection also showed improvements in noise reduction. However, a limit on the maximum water flow rate existed as too large of flow rate could result in un-starting the supersonic diffuser.

  9. Morphology and emplacement of a long channeled lava flow near Ascraeus Mons Volcano, Mars

    NASA Astrophysics Data System (ADS)

    Garry, W. Brent; Zimbelman, James R.; Gregg, Tracy K. P.

    2007-08-01

    Channeled lava flows, hundreds of kilometers long, are common on the lower flanks of the Tharsis Montes on Mars. Our analysis of a 690-km-long lava flow along the southwest perimeter of Ascraeus Mons shows that it was emplaced on low local slopes (<0.3°), with a deep channel (~20 m), and at high effusion rates (19,000-29,000 m3/s) calculated from the Graetz number. These parameters are similar to conditions needed to yield rapidly emplaced terrestrial flows >100 km in length, but the maximum effusion rates necessary on Earth are essentially the minimum for Martian flows. On the basis of our calculated effusion rates, the eruption duration was 3 to 7 Earth months, assuming a constant effusion rate and continuous eruption. The morphology of the Ascraeus Mons flow shows similarities to terrestrial and simulated channeled flows. Downstream changes in morphology resemble those observed in the 1907 flow, Mauna Loa Volcano, Hawaii and channeled polyethylene glycol (PEG) flows. Braided sections of the channel in the Ascraeus Mons flow contain islands which are hundreds of meters across and resemble features observed in the 1907 and 1984 flows on Mauna Loa Volcano. Crosscutting relationships suggest islands in the proximal section were shaped by thermal and mechanical erosion, whereas islands in the medial section are inferred to be material rafted by surges of lava through the channel. Overall, understanding the morphology of long lava flows on Mars is essential to the interpretation of their emplacement and constraining eruption conditions in the saddle regions of the Tharsis volcanoes.

  10. Rapid granular flows on a rough incline: phase diagram, gas transition, and effects of air drag.

    PubMed

    Börzsönyi, Tamás; Ecke, Robert E

    2006-12-01

    We report experiments on the overall phase diagram of granular flows on an incline with emphasis on high inclination angles where the mean layer velocity approaches the terminal velocity of a single particle free falling in air. The granular flow was characterized by measurements of the surface velocity, the average layer height, and the mean density of the layer as functions of the hopper opening, the plane inclination angle, and the downstream distance x of the flow. At high inclination angles the flow does not reach an x -invariant steady state over the length of the inclined plane. For low volume flow rates, a transition was detected between dense and very dilute (gas) flow regimes. We show using a vacuum flow channel that air did not qualitatively change the phase diagram and did not quantitatively modify mean flow velocities of the granular layer except for small changes in the very dilute gaslike phase.

  11. Aircraft Engine Sump Fire Mitigation, Phase 2

    NASA Technical Reports Server (NTRS)

    Rosenlieb, J. W.

    1978-01-01

    The effect of changes in the input parameters (air leakage flow rate and temperature and lubricating oil inlet flow rate and temperature) over a specified range on the flammability conditions within an aircraft engine bearing sump was investigated. An analytical study was performed to determine the effect of various parameters on the generation rate of oil vapor from oil droplets in a hot air stream flowing in a cylindrical tube. The ignition of the vapor-air mixture by an ignition source was considered. The experimental investigation demonstrated that fires would be ignited by a spark ignitor over the full range of air and oil flow rates and air temperatures evaluated. However, no fires could be ignited when the oil inlet temperature was maintained below 41.7 K (290 F). The severity of the fires ignited were found to be directly proportional to the hot air flow rate. Reasonably good correlation was found between the mixture temperature in the sump at the ignitor location and the flammability limits as defined by flammability theory; thus a fairly reliable experimental method of determining flammable conditions within a sump was demonstrated. The computerized mathematical model shows that oil droplet size and air temperature have the greatest influence on the generation rate of oil vapor.

  12. Spontaneous phase transition from free flow to synchronized flow in traffic on a single-lane highway.

    PubMed

    Jin, Cheng-Jie; Wang, Wei; Jiang, Rui; Zhang, H M; Wang, Hao

    2013-01-01

    Traffic flow complexity comes from the car-following and lane-changing behavior. Based on empirical data for individual vehicle speeds and time headways measured on a single-lane highway section, we have studied the traffic flow properties induced by pure car-following behavior. We have found that a spontaneous sudden drop in velocity could happen in a platoon of vehicles when the velocity of the leading vehicle is quite high (~70 km/h). In contrast, when the velocity of the leading vehicle in a platoon slows down, such a spontaneous sudden drop of velocity has not been observed. Our finding indicates that traffic breakdown on a single-lane road might be a phase transition from free flow to synchronized flow (F→S transition). We have found that the flow rate within the emergent synchronized flow can be either smaller or larger than the flow rate in the free flow within which the synchronized flow propagates. Our empirical findings support Kerner's three-phase theory in which traffic breakdown is associated with an F→S transition.

  13. Anxiety and cerebral blood flow during behavioral challenge. Dissociation of central from peripheral and subjective measures

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zohar, J.; Insel, T.R.; Berman, K.F.

    1989-06-01

    To investigate the relationship between anxiety and regional cerebral blood flow, we administered behavioral challenges to 10 patients with obsessive-compulsive disorder while measuring regional cerebral blood flow with the xenon 133 inhalation technique. Each patient was studied under three conditions: relaxation, imaginal flooding, and in vivo (actual) exposure to the phobic stimulus. Subjective anxiety, obsessive-compulsive ratings, and autonomic measures (heart rate, blood pressure) increased significantly, but respiratory rate and PCO/sub 2/ did not change across the three conditions. Regional cerebral blood flow increased slightly (in the temporal region) during imaginal flooding, but decreased markedly in several cortical regions during inmore » vivo exposure, when anxiety was highest by subjective and peripheral autonomic measures. These results demonstrate that intense anxiety can be associated with decreased rather than increased cortical perfusion and that ostensibly related states of anxiety (eg, anticipatory and obsessional anxiety) may be associated with opposite effects on regional cerebral blood flow.« less

  14. Impedance analysis of a disk-type SOFC using doped lanthanum gallate under power generation

    NASA Astrophysics Data System (ADS)

    Kato, Tohru; Nozaki, Ken; Negishi, Akira; Kato, Ken; Monma, Akihiko; Kaga, Yasuo; Nagata, Susumu; Takano, Kiyonami; Inagaki, Toru; Yoshida, Hiroyuki; Hosoi, Kei; Hoshino, Koji; Akbay, Taner; Akikusa, Jun

    Impedance measurements were carried out under practical power generation conditions in a disk-type SOFC, which may be utilized as a small-scale power generator. The tested cell was composed of doped lanthanum gallate (La 0.8Sr 0.2Ga 0.8Mg 0.15Co 0.05O 3- δ) as the electrolyte, Sm 0.5Sr 0.5CoO 3 as the cathode electrode and Ni/Ce 0.8Sm 0.2O 2 cermet as the anode electrode. The cell impedance was measured between 10 mHz and 10 kHz by varying the fuel utilization and gas flow rate and plotted in complex impedance diagrams. The observed impedance shows a large semi-circular pattern on the low frequency side. The semi-circular impedance, having a noticeably low characteristic frequency between 0.13 and 0.4 Hz, comes from the change in gas composition, originally caused by the cell reaction. The change in impedance with the fuel utilization (load current) and the gas flow rate agreed qualitatively well with the theoretical predictions from a simulation. This impedance was dominant under high fuel-utilization power-generation conditions. The impedance, which described the activation polarizations in the electrode reactions, was comparatively small and scarcely changed with the change in fuel utilization (load current) and gas flow rate.

  15. Rapid geomorphic change caused by glacial outburst floods and debris flows along Tahoma Creek, Mount Rainier, Washington, USA

    USGS Publications Warehouse

    Walder, J.S.; Driedger, C.L.

    1994-01-01

    As part of a hazards-assessment study, we examined the nature and rate of geomorphic change caused by outburst floods and debris flows along Tahoma Creek. Mount Rainier, since 1967. Archival aerial photographs of the area proved to be a rich source of qualitative geomorphic information. On the basis of limited direct evidence and considerations of stream hydrology, we conclude that nearly all of these debris flows began as outburst floods from South Tahoma Glacier. The water floods transformed to debris flows by incorporating large masses of sediment in a 2-km-long channel reach where the stream has incised proglacial sediments and debris-rich, stagnant glacier ice. Comparison of topographic maps for 1970 and 1991 shows that the average sediment flux out of the incised reach has been about 2 to 4 × 105 m3 a-1 corresponding to an average denudation rate in the upper part of the Tahoma Creek drainage basin of about 20 to 40 mm a-1, a value exceeded only rarely in basins affected by debris flows. However, little of this sediment has yet passed out of the Tahoma Creek basin. Comparison of geomorphic change at Tahoma Creek to that in two other alpine basins affected by outburst floods suggests that debris-rich stagnant ice can be an important source of sediment for debris flows as long as floods are frequent or channel slope is great.

  16. Dynamic rating curve assessment in hydrometric stations and calculation of the associated uncertainties : Quality and monitoring indicators

    NASA Astrophysics Data System (ADS)

    Morlot, Thomas; Perret, Christian; Favre, Anne-Catherine

    2013-04-01

    Whether we talk about safety reasons, energy production or regulation, water resources management is one of EDF's (French hydropower company) main concerns. To meet these needs, since the fifties EDF-DTG operates a hydrometric network that includes more than 350 hydrometric stations. The data collected allow real time monitoring of rivers (hydro meteorological forecasts at points of interests), as well as hydrological studies and the sizing of structures. Ensuring the quality of stream flow data is a priority. A rating curve is an indirect method of estimating the discharge in rivers based on water level measurements. The value of discharge obtained thanks to the rating curve is not entirely accurate due to the constant changes of the river bed morphology, to the precision of the gaugings (direct and punctual discharge measurements) and to the quality of the tracing. As time goes on, the uncertainty of the estimated discharge from a rating curve « gets older » and increases: therefore the final level of uncertainty remains particularly difficult to assess. Moreover, the current EDF capacity to produce a rating curve is not suited to the frequency of change of the stage-discharge relationship. The actual method does not take into consideration the variation of the flow conditions and the modifications of the river bed which occur due to natural processes such as erosion, sedimentation and seasonal vegetation growth. In order to get the most accurate stream flow data and to improve their reliability, this study undertakes an original « dynamic» method to compute rating curves based on historical gaugings from a hydrometric station. A curve is computed for each new gauging and a model of uncertainty is adjusted for each of them. The model of uncertainty takes into account the inaccuracies in the measurement of the water height, the quality of the tracing, the uncertainty of the gaugings and the aging of the confidence intervals calculated with a variographic analysis. These rating curves enable to provide values of stream flow taking into account the variability of flow conditions, while providing a model of uncertainties resulting from the aging of the rating curves. By taking into account the variability of the flow conditions and the life of the hydrometric station, this original dynamic method can answer important questions in the field of hydrometry such as « How many gaugings a year have to be made so as to produce stream flow data with an average uncertainty of X% ? » and « When and in which range of water flow do we have to realize those gaugings ? ». KEY WORDS : Uncertainty, Rating curve, Hydrometric station, Gauging, Variogram, Stream Flow

  17. On the calculation of air flow rates to ventilate closed-type stations in subway with the double-track tunnel

    NASA Astrophysics Data System (ADS)

    Kiyanitsa, LA

    2018-03-01

    Metro is not only the most promising kind of public transport but also an important part of infrastructure in a modern city. As a place where large groups of people gather, subway is to ensure the required air exchange at the passenger platforms of the stations. The air flow rate for airing the stations is also determined based on the required temperature, humidity and MAC of gases. The present study estimates the required air flow rate at the passenger platform of the closed-type subway station with the double-track tunnel given the standard air temperature, humidity and gas concentration, as well as based on the condition of the specified air flow feed and air changes per hour. The article proposes the scheme of air recirculation from the double-track tunnel to the station.

  18. "Hot-wire" microfluidic flowmeter based on a microfiber coupler.

    PubMed

    Yan, Shao-Cheng; Liu, Zeng-Yong; Li, Cheng; Ge, Shi-Jun; Xu, Fei; Lu, Yan-Qing

    2016-12-15

    Using an optical microfiber coupler (MC), we present a microfluidic platform for strong direct or indirect light-liquid interaction by wrapping a MC around a functionalized capillary. The light propagating in the MC and the liquid flowing in the capillary can be combined and divorced smoothly, keeping a long-distance interaction without the conflict of input and output coupling. Using this approach, we experimentally demonstrate a "hot-wire" microfluidic flowmeter based on a gold-integrated helical MC device. The microfluid inside the glass channel takes away the heat, then cools the MC and shifts the resonant wavelength. Due to the long-distance interaction and high temperature sensitivity, the proposed microfluidic flowmeter shows an ultrahigh flow rate sensitivity of 2.183 nm/(μl/s) at a flow rate of 1 μl/s. The minimum detectable change of the flow rate is around 9 nl/s at 1 μl/s.

  19. Thermal mapping of a pāhoehoe lava flow, Kīlauea Volcano

    NASA Astrophysics Data System (ADS)

    Patrick, Matthew; Orr, Tim; Fisher, Gary; Trusdell, Frank; Kauahikaua, James

    2017-02-01

    Pāhoehoe lava flows are a major component of Hawaiian eruptive activity, and an important part of basaltic volcanism worldwide. In recent years, pāhoehoe lava has destroyed homes and threatened parts of Hawai'i with inundation and disruption. In this study, we use oblique helicopter-borne thermal images to create high spatial resolution ( 1 m) georeferenced thermal maps of the active pāhoehoe flow on Kīlauea Volcano's East Rift Zone. Thermal maps were created on 27 days during 2014-2016 in the course of operational monitoring, encompassing a phase of activity that threatened the town of Pāhoa. Our results illustrate and reinforce how pāhoehoe flows are multicomponent systems consisting of the vent, master tube, distributary tubes, and surface breakouts. The thermal maps accurately depict the distribution and character of pāhoehoe breakouts through time, and also delineate the subsurface lava tube. Surface breakouts were distributed widely across the pāhoehoe flow, with significant portions concurrently active well upslope of the flow front, often concentrated in clusters of activity that evolved through time. Gradual changes to surface breakout distribution and migration relate to intrinsic processes in the flow, including the slow evolution of the distributary tube system. Abrupt disruptions to this system, and the creation of new breakouts (and associated hazards), were triggered by extrinsic forcing-namely fluctuations in lava supply rate at the vent which disrupted the master lava tube. Although the total area of a pāhoehoe flow has been suggested to relate to effusion rate, our results show that changes in the proportion of expansion vs. overplating can complicate this relationship. By modifying existing techniques, we estimate time-averaged discharge rates for the flow during 2014-2016 generally in the range of 1-2 m3 s- 1 (mean: 1.3 ± 0.4 m3 s- 1)-less than half of Kīlauea's typical eruption rate on the East Rift Zone and suggestive of a weak eruptive regime during 2014-2016. We caution, however, that this discharge rate approach requires further independent corroboration. The thermal maps provide the first synoptic characterization of pāhoehoe flow activity at high spatial resolution, essential both for operational hazard assessment and fundamental understanding of pāhoehoe behavior.

  20. Sensitivity analysis of a multilayer, finite-difference model of the Southeastern Coastal Plain regional aquifer system; Mississippi, Alabama, Georgia, and South Carolina

    USGS Publications Warehouse

    Pernik, Meribeth

    1987-01-01

    The sensitivity of a multilayer finite-difference regional flow model was tested by changing the calibrated values for five parameters in the steady-state model and one in the transient-state model. The parameters that changed under the steady-state condition were those that had been routinely adjusted during the calibration process as part of the effort to match pre-development potentiometric surfaces, and elements of the water budget. The tested steady-state parameters include: recharge, riverbed conductance, transmissivity, confining unit leakance, and boundary location. In the transient-state model, the storage coefficient was adjusted. The sensitivity of the model to changes in the calibrated values of these parameters was evaluated with respect to the simulated response of net base flow to the rivers, and the mean value of the absolute head residual. To provide a standard measurement of sensitivity from one parameter to another, the standard deviation of the absolute head residual was calculated. The steady-state model was shown to be most sensitive to changes in rates of recharge. When the recharge rate was held constant, the model was more sensitive to variations in transmissivity. Near the rivers, the riverbed conductance becomes the dominant parameter in controlling the heads. Changes in confining unit leakance had little effect on simulated base flow, but greatly affected head residuals. The model was relatively insensitive to changes in the location of no-flow boundaries and to moderate changes in the altitude of constant head boundaries. The storage coefficient was adjusted under transient conditions to illustrate the model 's sensitivity to changes in storativity. The model is less sensitive to an increase in storage coefficient than it is to a decrease in storage coefficient. As the storage coefficient decreased, the aquifer drawdown increases, the base flow decreased. The opposite response occurred when the storage coefficient was increased. (Author 's abstract)

  1. A Capillary Flow Dynamics-Based Sensing Modality for Direct Environmental Pathogen Monitoring.

    PubMed

    Klug, Katherine E; Reynolds, Kelly A; Yoon, Jeong-Yeol

    2018-04-20

    Toward ultra-simple and field-ready biosensors, we demonstrate a novel assay transducer mechanism based on interfacial property changes and capillary flow dynamics in antibody-conjugated submicron particle suspensions. Differential capillary flow is tunable, allowing pathogen quantification as a function of flow rate through a paper-based microfluidic device. Flow models based on interfacial and rheological properties indicate a significant relationship between the flow rate and the interfacial effects caused by target-particle aggregation. This mechanism is demonstrated for assays of Escherichia coli K12 in water samples and Zika virus (ZIKV) in blood serum. These assays achieved very low limits of detection compared with other demonstrated methods (1 log CFU/mL E. coli and 20 pg/mL ZIKV whole virus) with an operating time of 30 s, showing promise for environmental and health monitoring. © 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  2. Experimental investigation of a local recirculation photobioreactor for mass cultures of photosynthetic microorganisms.

    PubMed

    Moroni, Monica; Cicci, Agnese; Bravi, Marco

    2014-04-01

    The present work deals with the experimental fluid mechanics analysis of a wavy-bottomed cascade photobioreactor, to characterize the extent and period of recirculatory and straight-flowing streams establishing therein as a function of reactor inclination and liquid flow rate. The substream characterization via Feature Tracking (FT) showed that a local recirculation zone establishes in each vane only at inclinations ≤6° and that its location changes from the lower (≤3°) to the upper part of each vane (6°). A straight-flowing stream flows opposite (above or below) the local recirculation stream. The recirculation time ranges from 0.86 s to 0.23 s, corresponding, respectively, to the minimum flow rate at the minimum inclination and to the maximum flow rate at the maximum inclination where recirculation was observed. The increase of photosynthetic activity, resulting from the entailed "flash effect", was estimated to range between 102 and 113% with respect to equivalent tubular and bubble column photobioreactors. Copyright © 2013 Elsevier Ltd. All rights reserved.

  3. Stereoscopic Planar Laser-Induced Fluorescence Imaging at 500 kHz

    NASA Technical Reports Server (NTRS)

    Medford, Taylor L.; Danehy, Paul M.; Jones, Stephen B.; Jiang, N.; Webster, M.; Lempert, Walter; Miller, J.; Meyer, T.

    2011-01-01

    A new measurement technique for obtaining time- and spatially-resolved image sequences in hypersonic flows is developed. Nitric-oxide planar laser-induced fluorescence (NO PLIF) has previously been used to investigate transition from laminar to turbulent flow in hypersonic boundary layers using both planar and volumetric imaging capabilities. Low flow rates of NO were typically seeded into the flow, minimally perturbing the flow. The volumetric imaging was performed at a measurement rate of 10 Hz using a thick planar laser sheet that excited NO fluorescence. The fluorescence was captured by a pair of cameras having slightly different views of the flow. Subsequent stereoscopic reconstruction of these images allowed the three-dimensional flow structures to be viewed. In the current paper, this approach has been extended to 50,000 times higher repetition rates. A laser operating at 500 kHz excites the seeded NO molecules, and a camera, synchronized with the laser and fitted with a beam-splitting assembly, acquires two separate images of the flow. The resulting stereoscopic images provide three-dimensional flow visualizations at 500 kHz for the first time. The 200 ns exposure time in each frame is fast enough to freeze the flow while the 500 kHz repetition rate is fast enough to time-resolve changes in the flow being studied. This method is applied to visualize the evolving hypersonic flow structures that propagate downstream of a discrete protuberance attached to a flat plate. The technique was demonstrated in the NASA Langley Research Center s 31-Inch Mach 10 Air Tunnel facility. Different tunnel Reynolds number conditions, NO flow rates and two different cylindrical protuberance heights were investigated. The location of the onset of flow unsteadiness, an indicator of transition, was observed to move downstream during the tunnel runs, coinciding with an increase in the model temperature.

  4. Simple microfluidic stagnation point flow geometries

    PubMed Central

    Dockx, Greet; Verwijlen, Tom; Sempels, Wouter; Nagel, Mathias; Moldenaers, Paula; Hofkens, Johan; Vermant, Jan

    2016-01-01

    A geometrically simple flow cell is proposed to generate different types of stagnation flows, using a separation flow and small variations of the geometric parameters. Flows with high local deformation rates can be changed from purely rotational, over simple shear flow, to extensional flow in a region surrounding a stagnation point. Computational fluid dynamic calculations are used to analyse how variations of the geometrical parameters affect the flow field. These numerical calculations are compared to the experimentally obtained streamlines of different designs, which have been determined by high speed confocal microscopy. As the flow type is dictated predominantly by the geometrical parameters, such simple separating flow devices may alleviate the requirements for flow control, while offering good stability for a wide variety of flow types. PMID:27462382

  5. Define of internal recirculation coefficient for biological wastewater treatment in anoxic and aerobic bioreactors

    NASA Astrophysics Data System (ADS)

    Rossinskyi, Volodymyr

    2018-02-01

    The biological wastewater treatment technologies in anoxic and aerobic bioreactors with recycle of sludge mixture are used for the effective removal of organic compounds from wastewater. The change rate of sludge mixture recirculation between bioreactors leads to a change and redistribution of concentrations of organic compounds in sludge mixture in bioreactors and change hydrodynamic regimes in bioreactors. Determination of the coefficient of internal recirculation of sludge mixture between bioreactors is important for the choice of technological parameters of biological treatment (wastewater treatment duration in anoxic and aerobic bioreactors, flow capacity of recirculation pumps). Determination of the coefficient of internal recirculation of sludge mixture requires integrated consideration of hydrodynamic parameter (flow rate), kinetic parameter (rate of oxidation of organic compounds) and physical-chemical parameter of wastewater (concentration of organic compounds). The conducted numerical experiment from the proposed mathematical equations allowed to obtain analytical dependences of the coefficient of internal recirculation sludge mixture between bioreactors on the concentration of organic compounds in wastewater, the duration of wastewater treatment in bioreactors.

  6. Effect of sumatriptan on cerebral blood flow in the baboon model.

    PubMed

    Oliver, D W; Dormehl, I C; Hugo, N

    1994-08-01

    Changes in cerebral blood flow are implicated to be important in the pathophysiology of migraine. Furthermore, serotonin (5-HT) is known to be the most important substance in the etiology of migraine. Sumatriptan (CAS 103628-46-2), a 5-HTID receptor agonist was recently introduced in the treatment of migraine. In the present study a baboon model was used to investigate the changes in cerebral blood flow due to anaesthesia and pharmacological interventions using 99mTc-labelled hexamethylpropylene amine oxime (99mTc-HMPAO) and single photon emission computed tomography (SPECT). The effect of sumatriptan on cerebral blood flow was investigated after 10 min and again after 23 min, with the animal under anaesthesia, i.e. induction with ketamine and maintenance on thiopental. Sumatriptan did not alter the cerebral blood flow during the 10 min procedure. However, sumatriptan reversed the increased cerebral blood flow due to the prolonged anaesthesia (23 min), lowering the cerebral blood flow by more than 20%. No significant changes in the biochemical parameters (blood pressure, heart rate, pO2 and pCO2) were observed. These results also suggest that sumatriptan reverses the increased cerebral blood flow most likely via 5-HTID receptor stimulation.

  7. Influence of peak flow changes on the macroinvertebrate drift downstream of a Brazilian hydroelectric dam.

    PubMed

    Castro, D M P; Hughes, R M; Callisto, M

    2013-11-01

    Successive daily peak flows from hydropower plants can disrupt aquatic ecosystems and alter the composition and structure of macroinvertebrates downstream. We evaluated the influence of peak flow changes on macroinvertebrate drift downstream of a hydroelectric plant as a basis for determining ecological flows that might reduce the disturbance of aquatic biota. The aim of this study was to assess the influence of flow fluctuations on the seasonal and daily drift patterns of macroinvertebrates. We collected macroinvertebrates during fixed flow rates (323 m3.s-1 in the wet season and 111 m3.s-1 in the dry season) and when peak flows fluctuated (378 to 481 m3.s-1 in the wet season, and 109 to 173 m3.s-1 in the dry season) in 2010. We collected 31,924 organisms belonging to 46 taxa in the four sampling periods. Taxonomic composition and densities of drifting invertebrates differed between fixed and fluctuating flows, in both wet and dry seasons, but family richness varied insignificantly. We conclude that macroinvertebrate assemblages downstream of dams are influenced by daily peak flow fluctuations. When making environmental flow decisions for dams, it would be wise to consider drifting macroinvertebrates because they reflect ecological changes in downstream biological assemblages.

  8. Experimental investigation of the effect of air velocity on a unit cooler under frosting condition: a case study

    NASA Astrophysics Data System (ADS)

    Bayrak, Ergin; Çağlayan, Akın; Konukman, Alp Er S.

    2017-10-01

    Finned tube evaporators are used in a wide range of applications such as commercial and industrial cold/freezed storage rooms with high traffic loading under frosting conditions. In this case study, an evaporator with an integrated fan was manufactured and tested under frosting conditions by only changing the air flow rate in an ambient balanced type test laboratory compared to testing in a wind tunnel with a more uniform flow distribution in order to detect the effect of air flow rate on frosting. During the test, operation was performed separately based on three different air flow rates. The parameters concerning test operation such as the changes of air temperature, air relative humidity, surface temperature, air-side pressure drop and refrigerant side capacity etc. were followed in detail for each air flow rate. At the same time, digital images were captured in front of the evaporator; thus, frost thicknesses and blockage ratios at the course of fan stall were determined by using an image-processing technique. Consequently, the test and visual results showed that the trendline of air-side pressure drop increased slowly at the first stage of test operations, then increased linearly up to a top point and then the linearity was disrupted instantly. This point speculated the beginning of defrost operation for each case. In addition, despite detecting a velocity that needs to be avoided, a test applied at minimum air velocity is superior to providing minimum capacity in terms of loss of capacity during test operations.

  9. Investigation of Unsteady Tip Clearance Flow in a Low-Speed One and Half Stage Axial Compressor with LES And PIV

    NASA Technical Reports Server (NTRS)

    Hah, Chunill; Hathaway, Michael; Katz, Joseph; Tan, David

    2015-01-01

    The primary focus of this paper is to investigate how a rotor's unsteady tip clearance flow structure changes in a low speed one and half stage axial compressor when the rotor tip gap size is increased from 0.5 mm (0.49% of rotor tip blade chord, 2% of blade span) to 2.4 mm (2.34% chord, 4% span) at the design condition are investigated. The changes in unsteady tip clearance flow with the 0.62 % tip gap as the flow rate is reduced to near stall condition are also investigated. A Large Eddy Simulation (LES) is applied to calculate the unsteady flow field at these three flow conditions. Detailed Stereoscopic PIV (SPIV) measurements of the current flow fields were also performed at the Johns Hopkins University in a refractive index-matched test facility which renders the compressor blades and casing optically transparent. With this setup, the unsteady velocity field in the entire flow domain, including the flow inside the tip gap, can be measured. Unsteady tip clearance flow fields from LES are compared with the PIV measurements and both LES and PIV results are used to study changes in tip clearance flow structures. The current study shows that the tip clearance vortex is not a single structure as traditionally perceived. The tip clearance vortex is formed by multiple interlaced vorticities. Therefore, the tip clearance vortex is inherently unsteady. The multiple interlaced vortices never roll up to form a single structure. When phased-averaged, the tip clearance vortex appears as a single structure. When flow rate is reduced with the same tip gap, the tip clearance vortex rolls further upstream and the tip clearance vortex moves further radially inward and away from the suction side of the blade. When the tip gap size is increased at the design flow condition, the overall tip clearance vortex becomes stronger and it stays closer to the blade suction side and the vortex core extends all the way to the exit of the blade passage. Measured and calculated unsteady flow fields inside the tip gap agree fairly well. Instantaneous velocity vectors inside the tip gap from both the PIV and LES do show flow separation and reattachment at the entrance of tip gap as some earlier studies suggested. This area at the entrance of tip gap flow (the pressure side of the blade) is confined very close to the rotor tip section. With a small tip gap (0.5mm), the gap flow looks like a simple two-dimensional channel flow with larger velocity near the casing for both flow rates. A small area with a sharp velocity gradient is observed just above the rotor tip. This strong shear layer is turned radially inward when it collides with the incoming flow and forms the core structure of the tip clearance vortex. When tip gap size is increased to 2.4 mm at the design operation, the radial profile of the tip gap flow changes drastically. With the large tip gap, the gap flow looks like a two-dimensional channel flow only near the casing. Near the rotor top section, a bigger region with very large shear and reversed flow is observed.

  10. Impact of High-flow Nasal Cannula Therapy in Quality Improvement and Clinical Outcomes in a Non-invasive Ventilation Device-free Pediatric Intensive Care Unit.

    PubMed

    Can, Fulva Kamit; Anil, Ayse Berna; Anil, Murat; Zengin, Neslihan; Bal, Alkan; Bicilioglu, Yuksel; Gokalp, Gamze; Durak, Fatih; Ince, Gulberat

    2017-10-15

    To analyze the change in quality indicators due to the use of high-flow nasal cannula therapy as a non-invasive ventilation method in children with respiratory distress/failure in a non-invasive ventilation device-free pediatric intensive care unit. Retrospective chart review of children with respiratory distress/failure admitted 1 year before (period before high-flow nasal cannula therapy) and 1 year after (period after high-flow nasal cannula therapy) the introduction of high-flow nasal cannula therapy. We compared quality indicators as rate of mechanical ventilation, total duration of mechanical ventilation, rate of re-intubation, pediatric intensive care unit length of stay, and mortality rate between these periods. Between November 2012 and November 2014, 272 patients: 141 before and 131 after high-flow nasal cannula therapy were reviewed (median age was 20.5 mo). Of the patients in the severe respiratory distress/failure subgroup, the rate of intubation was significantly lower in period after than in period before high-flow nasal cannula therapy group (58.1% vs. 76.1%; P <0.05). The median pediatric intensive care unit length of stay was significantly shorter in patients who did not require mechanical ventilation in the period after than in the period before high-flow nasal cannula therapy group (3d vs. 4d; P<0,05). Implementation of high-flow nasal cannula therapy in pediatric intensive care unit significantly improves the quality of therapy and its outcomes.

  11. Field-effect Flow Control in Polymer Microchannel Networks

    NASA Technical Reports Server (NTRS)

    Sniadecki, Nathan; Lee, Cheng S.; Beamesderfer, Mike; DeVoe, Don L.

    2003-01-01

    A new Bio-MEMS electroosmotic flow (EOF) modulator for plastic microchannel networks has been developed. The EOF modulator uses field-effect flow control (FEFC) to adjust the zeta potential at the Parylene C microchannel wall. By setting a differential EOF pumping rate in two of the three microchannels at a T-intersection with EOF modulators, the induced pressure at the intersection generated pumping in the third, field-free microchannel. The EOF modulators are able to change the magnitude and direction of the pressure pumping by inducing either a negative or positive pressure at the intersection. The flow velocity is tracked by neutralized fluorescent microbeads in the microchannels. The proof-of-concept of the EOF modulator described here may be applied to complex plastic ,microchannel networks where individual microchannel flow rates are addressable by localized induced-pressure pumping.

  12. Flow separation characteristics of unstable dispersions

    NASA Astrophysics Data System (ADS)

    Voulgaropoulos, Victor; Zhai, Lusheng; Angeli, Panagiota

    2016-11-01

    Drops of a low viscosity oil are introduced through a multi-capillary inlet during the flow of water in a horizontal pipe. The flow rates of the continuous water phase are kept in the turbulent region while the droplets are injected at similar flow rates (with oil fractions ranging from 0.15 to 0.60). The acrylic pipe (ID of 37mm) is approximately 7m long. Measurements are conducted at three different axial locations to illustrate how the flow structures are formed and develop along the pipe. Initial observations are made on the flow patterns through high-speed imaging. Stratification is observed for the flow rates studied, indicating that the turbulent dispersive forces are lower than the gravity ones. These results are complemented with a tomography system acquiring measurements at the same locations and giving the cross-sectional hold-up. The coalescence dynamics are strong in the dense-packed drop layer and thus measurements with a dual-conductance probe are conducted to capture any drop size changes. It is found that the drop size variations depend on the spatial configuration of the drops, the initial drop size along with the continuous and dispersed phase velocities. Project funded under Chevron Energy Technology.

  13. Packaged peristaltic micropump for controlled drug delivery application

    NASA Astrophysics Data System (ADS)

    Vinayakumar, K. B.; Nadiger, Girish; R. Shetty, Vikas; Dinesh, N. S.; Nayak, M. M.; Rajanna, K.

    2017-01-01

    Micropump technology has evolved significantly in the last two decades and is finding a variety of applications ranging from μTAS (micro Total Analysis System) to drug delivery. However, the application area of the micropump is limited owing to: simple pumping mechanism, ease of handling, controlled (microliter to milliliter) delivery, continuous delivery, and accuracy in flow rate. Here, the author presents the design, development, characterization, and precision flow controlling of a DC-motor driven peristaltic pump for controlled drug delivery application. All the micropump components were fabricated using the conventional fabrication technique. The volume flow variation of the pump has been characterized for different viscous fluids. The change in volume flow due to change in back pressure has been presented in detail. The fail-safe mode operation of the pump has been tested and leak rate was measured (˜0.14% leak for an inlet pressure of 140 kPa) for different inlet pressures. The precision volume flow of the pump has been achieved by measuring the pinch cam position and load current. The accuracy in the volume flow has been measured after 300 rotations. Finally, the complete system has been integrated with the necessary electronics and an android application has been developed for the self-administration of bolus and basal delivery of insulin.

  14. Modelling Greenland Outlet Glaciers

    NASA Technical Reports Server (NTRS)

    vanderVeen, Cornelis; Abdalati, Waleed (Technical Monitor)

    2001-01-01

    The objective of this project was to develop simple yet realistic models of Greenland outlet glaciers to better understand ongoing changes and to identify possible causes for these changes. Several approaches can be taken to evaluate the interaction between climate forcing and ice dynamics, and the consequent ice-sheet response, which may involve changes in flow style. To evaluate the icesheet response to mass-balance forcing, Van der Veen (Journal of Geophysical Research, in press) makes the assumption that this response can be considered a perturbation on the reference state and may be evaluated separately from how this reference state evolves over time. Mass-balance forcing has an immediate effect on the ice sheet. Initially, the rate of thickness change as compared to the reference state equals the perturbation in snowfall or ablation. If the forcing persists, the ice sheet responds dynamically, adjusting the rate at which ice is evacuated from the interior to the margins, to achieve a new equilibrium. For large ice sheets, this dynamic adjustment may last for thousands of years, with the magnitude of change decreasing steadily over time as a new equilibrium is approached. This response can be described using kinematic wave theory. This theory, modified to pertain to Greenland drainage basins, was used to evaluate possible ice-sheet responses to perturbations in surface mass balance. The reference state is defined based on measurements along the central flowline of Petermann Glacier in north-west Greenland, and perturbations on this state considered. The advantage of this approach is that the particulars of the dynamical flow regime need not be explicitly known but are incorporated through the parameterization of the reference ice flux or longitudinal velocity profile. The results of the kinematic wave model indicate that significant rates of thickness change can occur immediately after the prescribed change in surface mass balance but adjustments in flow rapidly diminish these rates to a few cm/yr at most. The time scale for adjustment is of the order of a thousand years or so.

  15. Modelling carotid artery adaptations to dynamic alterations in pressure and flow over the cardiac cycle

    PubMed Central

    Cardamone, L.; Valentín, A.; Eberth, J. F.; Humphrey, J. D.

    2010-01-01

    Motivated by recent clinical and laboratory findings of important effects of pulsatile pressure and flow on arterial adaptations, we employ and extend an established constrained mixture framework of growth (change in mass) and remodelling (change in structure) to include such dynamical effects. New descriptors of cell and tissue behavior (constitutive relations) are postulated and refined based on new experimental data from a transverse aortic arch banding model in the mouse that increases pulsatile pressure and flow in one carotid artery. In particular, it is shown that there was a need to refine constitutive relations for the active stress generated by smooth muscle, to include both stress- and stress rate-mediated control of the turnover of cells and matrix and to account for a cyclic stress-mediated loss of elastic fibre integrity and decrease in collagen stiffness in order to capture the reported evolution, over 8 weeks, of luminal radius, wall thickness, axial force and in vivo axial stretch of the hypertensive mouse carotid artery. We submit, therefore, that complex aspects of adaptation by elastic arteries can be predicted by constrained mixture models wherein individual constituents are produced or removed at individual rates and to individual extents depending on changes in both stress and stress rate from normal values. PMID:20484365

  16. Detection of linear ego-acceleration from optic flow.

    PubMed

    Festl, Freya; Recktenwald, Fabian; Yuan, Chunrong; Mallot, Hanspeter A

    2012-07-20

    Human observers are able to estimate various ego-motion parameters from optic flow, including rotation, translational heading, time-to-collision (TTC), time-to-passage (TTP), etc. The perception of linear ego-acceleration or deceleration, i.e., changes of translational velocity, is less well understood. While time-to-passage experiments indicate that ego-acceleration is neglected, subjects are able to keep their (perceived) speed constant under changing conditions, indicating that some sense of ego-acceleration or velocity change must be present. In this paper, we analyze the relation of ego-acceleration estimates and geometrical parameters of the environment using simulated flights through cylindrical and conic (narrowing or widening) corridors. Theoretical analysis shows that a logarithmic ego-acceleration parameter, called the acceleration rate ρ, can be calculated from retinal acceleration measurements. This parameter is independent of the geometrical layout of the scene; if veridical ego-motion is known at some instant in time, acceleration rate allows updating of ego-motion without further depth-velocity calibration. Results indicate, however, that subjects systematically confuse ego-acceleration with corridor narrowing and ego-deceleration with corridor widening, while veridically judging ego-acceleration in straight corridors. We conclude that judgments of ego-acceleration are based on first-order retinal flow and do not make use of acceleration rate or retinal acceleration.

  17. Change in oral health status associated with menopause in Japanese dental hygienists.

    PubMed

    Yoshida, N; Sugimoto, K; Suzuki, S; Kudo, H

    2018-02-01

    Oral symptoms such as xerostomia and burning mouth syndrome have been recognized to increase associated with menopause. The purpose of this study was to clarify the changes in oral health as well as systemic health due to menopause and their relations with hormonal change and mental status. Ninety-seven female dental hygienists aged 40-59 years were assigned to premenopausal, menopausal and post-menopausal groups based on self-reported menstrual condition. Subjective health statuses were evaluated by questionnaire, and objective holistic and oral statuses were evaluated by measuring serum 17β-estradiol (E2), salivary flow rate, α-amylase and secretory IgA (SIgA) and taste sensitivity. A significant difference among the three groups was observed in the self-rating questionnaire of depression (SRQ-D) score and serum E2 level as well as unstimulated salivary flow rate, whereas no significant difference was observed in Simplified menopausal index, Short-Form 36-Item Health Survey, General Oral Health Assessment Index, salivary α-amylase activity, salivary SIgA concentration and taste threshold. Serum E2 levels positively correlated with unstimulated salivary flow rates and negatively correlated with SRQ-D scores and α-amylase activities. The results demonstrated a negative correlation between E2 levels and SRQ-D scores as well as salivary α-amylase activities, suggesting an influence of E2 on mental condition. Furthermore, E2 decrease may result in reduction of salivary flow which in turn causes various problems of oral health. Since the participants were graduates from several dental hygienist schools and working at various places, these results can be generalized to Japanese dental hygienists to some extent. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  18. Hillslope-channel coupling in a steep Hawaiian catchment accelerates erosion rates over 100-fold

    NASA Astrophysics Data System (ADS)

    Stock, J. D.; Hanshaw, M. N.; Rosener, M.; Schmidt, K. M.; Brooks, B. A.; Tribble, G.; Jacobi, J.

    2009-12-01

    In tropical watersheds, hillslope changes are producing increasing amounts of fine sediment that can be quickly carried to reefs by channels. Suspended sediment concentrations off the reefs of Molokai, Hawaii, chronically exceed a toxic level of 10 mg/L, threatening reef ecosystems. We hypothesize that historic conversion of watersheds from soil creep to overland flow erosion increased both magnitude and frequency of sediment flooding adjacent reefs. We combined surficial and ecological mapping, hillslope and stream gages, and novel sensors to locate, quantify and model the generation of fine sediments polluting the Molokai reef. Ecological and geomorphic mapping from LiDAR and multi-spectral imagery located a subset of overland flow areas with vegetation cover below a threshold value preventing erosion. Here, feral goat grazing exposed cohesive volcanic soils whose low matrix hydraulic conductivities (1-20 mm/hour) promote Horton overland flow erosion. We instrumented steep, barren hillslopes with soil moisture sensors, overland flow meters, Parshall flumes, ISCO sediment samplers, and a rain gage and conducted repeat Tripod LiDAR and infiltration tests. To characterize soil resistance here and elsewhere to overland flow erosion, we deployed a Cohesive Strength Meter (CSM) to simulate the stresses of flowing water. At the 13.5 km 2 watershed mouth we used a USGS stream gage and ISCO sediment sampler to estimate total load. Over 2 years, storms triggered overland flow during rainfall intensities above 10-15 mm/hr. Overland flow meters indicate such flows can be up to 3 cm deep, with a tendency to deepen downslope. CSM tests indicate that these depths are insufficient to erode soils where vegetation is dense, but far above threshold values of 2-3 mm depth for bare soil erosion. Sediment ratings curves for both hillslope and downstream catchment gages show strong clock-wise hysteresis during the first intense storms in the Fall, becoming linear later in the rainy season. During Fall storms, sediment concentration is often 10X higher at a given stage. During intense Fall storms, we measured erosion rates using erosion pins (1.0 cm/a), suspended sediment flux (1.5 cm/a) and repeat tripod LiDAR (1.7 cm/a). These rates are at least 100-fold greater than the long-term lowering rate of 0.13 mm/a. A sediment budget constructed by extrapolating hillslope lowering rates to the portions of the catchments mapped as overland flow hotspots predicts a total yearly flux of ~ 6500 t, in agreement with the measured total of ~6200 t. A decadal record illustrates that rainfall intensities sufficient to generate overland flow occur for at least 8-10 hours every year, coincident with 1-3 large storm events. We hypothesize that high lowering rates reflect a combination of long-duration overland flow events, and availability of weathered soils that can be entrained by thin flows. It appears that the generation of loose, seasonally weathered silt is a 1st order control on the amount of sediment exported to the reef. If climate change increases storm frequency or duration, or decreases vegetation cover, sediment loading rates to the reef here could increase dramatically.

  19. The effect of modeled recharge distribution on simulated groundwater availability and capture.

    PubMed

    Tillman, F D; Pool, D R; Leake, S A

    2015-01-01

    Simulating groundwater flow in basin-fill aquifers of the semiarid southwestern United States commonly requires decisions about how to distribute aquifer recharge. Precipitation can recharge basin-fill aquifers by direct infiltration and transport through faults and fractures in the high-elevation areas, by flowing overland through high-elevation areas to infiltrate at basin-fill margins along mountain fronts, by flowing overland to infiltrate along ephemeral channels that often traverse basins in the area, or by some combination of these processes. The importance of accurately simulating recharge distributions is a current topic of discussion among hydrologists and water managers in the region, but no comparative study has been performed to analyze the effects of different recharge distributions on groundwater simulations. This study investigates the importance of the distribution of aquifer recharge in simulating regional groundwater flow in basin-fill aquifers by calibrating a groundwater-flow model to four different recharge distributions, all with the same total amount of recharge. Similarities are seen in results from steady-state models for optimized hydraulic conductivity values, fit of simulated to observed hydraulic heads, and composite scaled sensitivities of conductivity parameter zones. Transient simulations with hypothetical storage properties and pumping rates produce similar capture rates and storage change results, but differences are noted in the rate of drawdown at some well locations owing to the differences in optimized hydraulic conductivity. Depending on whether the purpose of the groundwater model is to simulate changes in groundwater levels or changes in storage and capture, the distribution of aquifer recharge may or may not be of primary importance. Published 2014. This article is a U.S. Government work and is in the public domain in the USA.

  20. Groundwater-Seepage Meter

    NASA Technical Reports Server (NTRS)

    Walthall, Harry G.; Reay, William G.

    1993-01-01

    Instrument measures seepage of groundwater into inland or coastal body of water. Positioned at depth as great as 40 meters, and measures flow at low rate and low pressure differential. Auxiliary pressure meter provides data for correlation of flow of groundwater with tides and sea states. Seepage meter operates independently for several weeks. Its sampling rate adjusted to suit hydrologic conditions; to measure more frequently when conditions changing rapidly. Used in water-quality management and for biological and geological research. Potential industrial uses include measurement of seepage of caustic and corrosive liquids.

  1. Performance monitoring can boost turboexpander efficiency

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    McIntire, R.

    1982-07-05

    Focuses on the turboexpander/refrigeration system's radial expander and radial compressor. Explains that radial expander efficiency depends on mass flow rate, inlet pressure, inlet temperature, discharge pressure, gas composition, and shaft speed. Discusses quantifying the performance of the separate components over a range of operating conditions; estimating the increase in performance associated with any hardware change; and developing an analytical (computer) model of the entire system by using the performance curve of individual components. Emphasizes antisurge control and modifying Q/N (flow rate/ shaft speed).

  2. Proceedings of the International Cryocoolers Conference (4th) Held in Easton, Maryland on 25-26 September 1986

    DTIC Science & Technology

    1987-10-30

    simple relationship for the required refrigerant mass flow rate, m, for a given cooling load, q1l m = where Ah is the enthalpy difference between the cool...compressor concepts were tested to determine their performance. No measurable difference in performance was found and the first, more compact, concept was...resulting change in orifice size adjusts the mass flow rate through the valve. By reducing excursions in the pressure difference across the J-T valve, the

  3. Estimation of Flow Channel Parameters for Flowing Gas Mixed with Air in Atmospheric-pressure Plasma Jets

    NASA Astrophysics Data System (ADS)

    Yambe, Kiyoyuki; Saito, Hidetoshi

    2017-12-01

    When the working gas of an atmospheric-pressure non-equilibrium (cold) plasma flows into free space, the diameter of the resulting flow channel changes continuously. The shape of the channel is observed through the light emitted by the working gas of the atmospheric-pressure plasma. When the plasma jet forms a conical shape, the diameter of the cylindrical shape, which approximates the conical shape, defines the diameter of the flow channel. When the working gas flows into the atmosphere from the inside of a quartz tube, the gas mixes with air. The molar ratio of the working gas and air is estimated from the corresponding volume ratio through the relationship between the diameter of the cylindrical plasma channel and the inner diameter of the quartz tube. The Reynolds number is calculated from the kinematic viscosity of the mixed gas and the molar ratio. The gas flow rates for the upper limit of laminar flow and the lower limit of turbulent flow are determined by the corresponding Reynolds numbers estimated from the molar ratio. It is confirmed that the plasma jet length and the internal plasma length associated with strong light emission increase with the increasing gas flow rate until the rate for the upper limit of laminar flow and the lower limit of turbulent flow, respectively. Thus, we are able to explain the increasing trend in the plasma lengths with the diameter of the flow channel and the molar ratio by using the cylindrical approximation.

  4. Nonlinear Response of Iceberg Melting to Ocean Currents

    NASA Astrophysics Data System (ADS)

    Cenedese, C.; FitzMaurice, A.; Straneo, F.

    2017-12-01

    Icebergs calving into Greenlandic Fjords frequently experience strongly sheared flows over their draft, but the impact of this flow past the iceberg on the melt plumes generated along the iceberg sides is not fully captured by existing parameterizations. We present a series of novel laboratory experiments to determine the dependence of side submarine melt rates on a background flow. We show, for the first time, that two distinct regimes of melting exist depending on the melt plume behavior (side-attached or side-detached). These two regimes produce a nonlinear dependence of melt rate on velocity, and different distributions of meltwater in the water column. Iceberg meltwater may either be confined to a thin surface layer, when the melt plumes are side-attached, or mixed down to the iceberg draft, when the melt plumes are side-detached. In a two-layer vertically sheared flow the average flow speed in existing melt parameterizations gives an underestimate of the submarine melt rate, in part due to the nonlinearity of the dependence of melt rate on flow speed, but also because vertical shear in the velocity profile fundamentally changes the flow splitting around the ice block and consequently the velocity felt by the ice surface. Including this nonlinear velocity dependence in melting parameterizations applied to observed icebergs increases iceberg side melt in the attached regime, improving agreement with observations of iceberg submarine melt rates. We show that both attached and detached plume regimes are relevant to icebergs observed in a Greenland fjord.

  5. Controlled synthesis of germanium nanoparticles by nonthermal plasmas

    NASA Astrophysics Data System (ADS)

    Ahadi, Amir Mohammad; Hunter, Katharine I.; Kramer, Nicolaas J.; Strunskus, Thomas; Kersten, Holger; Faupel, Franz; Kortshagen, Uwe R.

    2016-02-01

    The size, composition, and crystallinity of plasma produced nanoparticles are crucial factors for their physical and chemical properties. Here, we investigate the role of the process gas composition, particularly the hydrogen (H2) flow rate, on germanium (Ge) nanoparticles synthesized from a chlorinated precursor by nonthermal plasma. We demonstrate that the gas composition can significantly change the nanoparticle size and also adjust the surface chemistry by altering the dominant reaction mechanisms. A red shift of the Ge-Clx infrared absorptions with increasing H2 flow indicates a weakening of the Ge-Clx bonds at high H2 content. Furthermore, by changing the gas composition, the nanoparticles microstructure can be controlled from mostly amorphous at high hydrogen flow to diamond cubic crystalline at low hydrogen flow.

  6. Passive flow regulators for drug delivery and hydrocephalus treatment

    NASA Astrophysics Data System (ADS)

    Chappel, E.; Dumont-Fillon, D.; Mefti, S.

    2014-03-01

    Passive flow regulators are usually intended to deliver or drain a fluid at a constant rate independently from pressure variations. New designs of passive flow regulators made of a stack of a silicon membrane anodically bonded to a Pyrex substrate are proposed. A first design has been built for the derivation of cerebrospinal fluid (CSF) towards peritoneum for hydrocephalus treatment. The device allows draining CSF at the patient production rate independently from postural changes. The flow rate is regulated at 20 ml/h in the range 10 to 40 mbar. Specific features to adjust in vivo the nominal flow rate are shown. A second design including high pressure shut-off feature has been made. The intended use is drug delivery with pressurized reservoir of typically 100 to 300 mbar. In both cases, the membrane comprises several holes facing pillars in the Pyrex substrate. These pillars are machined in a cavity which ensures a gap between the membrane and the pillars at rest. The fluid in the pressurized reservoir is directly in contact with the top surface of the membrane, inducing its deflection towards Pyrex substrate and closing progressively the fluidic pathway through each hole of the membrane. Since the membrane deflection is highly non-linear, FEM simulations have been performed to determine both radial position and diameter of the membrane holes that ensure a constant flow rate for a given range of pressure.

  7. Facilitated strontium transport by remobilization of strontium-containing secondary precipitates in Hanford Site subsurface.

    PubMed

    Wang, Guohui; Um, Wooyong

    2013-03-15

    Significantly enhanced immobilization of radionuclides (such as (90)Sr and (137)Cs) due to adsorption and coprecipitation with neo-formed colloid-sized secondary precipitates has been reported at the U.S. Department of Energy's Hanford Site. However, the stability of these secondary precipitates containing radionuclides in the subsurface under changeable field conditions is not clear. Here, the authors tested the remobilization possibility of Sr-containing secondary precipitates (nitrate-cancrinite) in the subsurface using saturated column experiments under different geochemical and flow conditions. The columns were packed with quartz sand that contained secondary precipitates (nitrate-cancrinite containing Sr), and leached using colloid-free solutions under different flow rates, varying pH, and ionic strength conditions. The results indicate remobilization of the neo-formed secondary precipitates could be possible given a change of pH of ionic strength and flow rate conditions. The remobility of the neo-formed precipitates increased with the rise in the leaching solution flow rate and pH (in a range of pH 4-11), as well as with decreasing solution ionic strength. The increased mobility of Sr-containing secondary precipitates with changing background conditions can be a potential source for additional radionuclide transport in Hanford Site subsurface environments. Published by Elsevier B.V.

  8. Mathematical modelling of flow distribution in the human cardiovascular system

    NASA Technical Reports Server (NTRS)

    Sud, V. K.; Srinivasan, R. S.; Charles, J. B.; Bungo, M. W.

    1992-01-01

    The paper presents a detailed model of the entire human cardiovascular system which aims to study the changes in flow distribution caused by external stimuli, changes in internal parameters, or other factors. The arterial-venous network is represented by 325 interconnected elastic segments. The mathematical description of each segment is based on equations of hydrodynamics and those of stress/strain relationships in elastic materials. Appropriate input functions provide for the pumping of blood by the heart through the system. The analysis employs the finite-element technique which can accommodate any prescribed boundary conditions. Values of model parameters are from available data on physical and rheological properties of blood and blood vessels. As a representative example, simulation results on changes in flow distribution with changes in the elastic properties of blood vessels are discussed. They indicate that the errors in the calculated overall flow rates are not significant even in the extreme case of arteries and veins behaving as rigid tubes.

  9. Method and apparatus for simultaneous determination of fluid mass flow rate, mean velocity and density

    DOEpatents

    Hamel, William R.

    1984-01-01

    This invention relates to a new method and new apparatus for determining fluid mass flowrate and density. In one aspect of the invention, the fluid is passed through a straight cantilevered tube in which transient oscillation has been induced, thus generating Coriolis damping forces on the tube. The decay rate and frequency of the resulting damped oscillation are measured, and the fluid mass flowrate and density are determined therefrom. In another aspect of the invention, the fluid is passed through the cantilevered tube while an electrically powered device imparts steady-state harmonic excitation to the tube. This generates Coriolis tube-damping forces which are dependent on the mass flowrate of the fluid. Means are provided to respond to incipient flow-induced changes in the amplitude of vibration by changing the power input to the excitation device as required to sustain the original amplitude of vibration. The fluid mass flowrate and density are determined from the required change in power input. The invention provides stable, rapid, and accurate measurements. It does not require bending of the fluid flow.

  10. Hydrologic analysis of Mojave River Basin, California, using electric analog model

    USGS Publications Warehouse

    Hardt, W.F.

    1971-01-01

    The water needs of the Mojave River basin will increase because of population and industrial growth. The Mojave Water Agency is responsible for providing sufficient water of good quality for the full economic development of the area. The U.S. Geological Survey suggested an electric analog model of the basin as a predictive tool to aid management. About 1,375 square miles of the alluvial basin was simulated by a passive resistor-capacitor network. The Mojave River, the main source of recharge, was simulated by subdividing the river into 13 reaches, depending on intermittent or perennial flow and on phreatophytes. The water loss to the aquifer was based on records at five gaging stations. The aquifer system depends on river recharge to maintain the water table as most of the ground-water pumping and development is adjacent to the river. The accuracy and reliability of the model was assessed by comparing the water-level changes computed by the model for the period 1930-63 with the changes determined from field data for the same period. The model was used to predict the effects on the physical system by determining basin-wide water-level changes from 1930-2000 under different pumping rates and extremes in flow of the Mojave River. Future pumping was based on the 1960-63 rate, on an increase of 20 percent from this rate, and on population projections to 2000 in the Barstow area. For future predictions, the Mojave River was modeled as average flow based on 1931-65 records and also as high flow, 1937-46, and low flow, 1947-65. Other model runs included water-level change 1930-63 assuming aquifer depletion only and no recharge, effects of a well field pumping 10,000 acre-feet in 4 months north of Victorville and southeast of Yermo, and effects of importing 10,000, 35,000, and 50,800 acre-feet of water per year from the California Water Project into the Mojave River for conveyance downstream.

  11. In search of earthquake-related hydrologic and chemical changes along Hayward Fault

    USGS Publications Warehouse

    King, C.-Y.; Basler, D.; Presser, T.S.; Evans, William C.; White, L.D.; Minissale, A.

    1994-01-01

    Flow and chemical measurements have been made about once a month, and more frequently when required, since 1976 at two springs in Alum Rock Park in eastern San Jose, California, and since 1980 at two shallow wells in eastern Oakland in search of earthquake-related changes. All sites are on or near the Hayward Fault and are about 55 km apart. Temperature, electric conductivity, and water level or flow rate were measured in situ with portable instruments. Water samples were collected for later chemical and isotopic analyses in the laboratory. The measured flow rate at one of the springs showed a long-term decrease of about 40% since 1987, when a multi-year drought began in California. It also showed several increases that lasted a few days to a few months with amplitudes of 2.4 to 8.6 times the standard deviations above the background rate. Five of these increases were recorded shortly after nearby earthquakes of magnitude 5.0 or larger, and may have resulted from unclogging of the flow path and increase of permeability caused by strong seismic shaking. Two other flow increases were possibly induced by exceptionally heavy rainfalls. The water in both wells showed seasonal temperature and chemical variations, largely in response to rainfall. In 1980 the water also showed some clear chemical changes unrelated to rainfall that lasted a few months; these changes were followed by a magnitude 4 earthquake 37 km away. The chemical composition at one of the wells and at the springs also showed some longer-term variations that were not correlated with rainfall but possibly correlated with the five earthquakes mentioned above. These correlations suggest a common tectonic origin for the earthquakes and the anomalies. The last variation at the affected well occurred abruptly in 1989, shortly before a magnitude 5.0 earthquake 54 km away. ?? 1993.

  12. Shifts in the suitable habitat available for brown trout (Salmo trutta L.) under short-term climate change scenarios.

    PubMed

    Muñoz-Mas, R; Lopez-Nicolas, A; Martínez-Capel, F; Pulido-Velazquez, M

    2016-02-15

    The impact of climate change on the habitat suitability for large brown trout (Salmo trutta L.) was studied in a segment of the Cabriel River (Iberian Peninsula). The future flow and water temperature patterns were simulated at a daily time step with M5 models' trees (NSE of 0.78 and 0.97 respectively) for two short-term scenarios (2011-2040) under the representative concentration pathways (RCP 4.5 and 8.5). An ensemble of five strongly regularized machine learning techniques (generalized additive models, multilayer perceptron ensembles, random forests, support vector machines and fuzzy rule base systems) was used to model the microhabitat suitability (depth, velocity and substrate) during summertime and to evaluate several flows simulated with River2D©. The simulated flow rate and water temperature were combined with the microhabitat assessment to infer bivariate habitat duration curves (BHDCs) under historical conditions and climate change scenarios using either the weighted usable area (WUA) or the Boolean-based suitable area (SA). The forecasts for both scenarios jointly predicted a significant reduction in the flow rate and an increase in water temperature (mean rate of change of ca. -25% and +4% respectively). The five techniques converged on the modelled suitability and habitat preferences; large brown trout selected relatively high flow velocity, large depth and coarse substrate. However, the model developed with support vector machines presented a significantly trimmed output range (max.: 0.38), and thus its predictions were banned from the WUA-based analyses. The BHDCs based on the WUA and the SA broadly matched, indicating an increase in the number of days with less suitable habitat available (WUA and SA) and/or with higher water temperature (trout will endure impoverished environmental conditions ca. 82% of the days). Finally, our results suggested the potential extirpation of the species from the study site during short time spans. Copyright © 2015 Elsevier B.V. All rights reserved.

  13. Combined Climate and Flow Abstraction Impacts on an Aggrading Alpine River

    NASA Astrophysics Data System (ADS)

    Bakker, M.; Costa, A.; Silva, T. A.; Stutenbecker, L.; Girardclos, S.; Loizeau, J. L.; Molnar, P.; Schlunegger, F.; Lane, S. N.

    2017-12-01

    Recent climatic warming and associated glacial retreat may have a large impact on sediment release and transfer in Alpine river basins. In parallel, the sediment transport capacity of many European Alpine streams is affected by hydropower exploitation, notably where flow is abstracted but the sediment supply to the headwaters is maintained at flow intakes. Here, we investigate the combined effects of climate change and flow abstraction on morphodynamics and sediment transfer in one such Alpine stream, the Borgne River, Switzerland. A unique dataset forms the basis for determining sediment deposition and transfer: (1) a set of high resolution Digital Elevation Models (DEMs) of braided river reaches is derived through applying Structure from Motion (SfM) photogrammetry to archival aerial photographs available for the period 1959-2014; (2) flow intake management data is used for the reconstruction of (up- and downstream) discharge and sediment supply since 1977. Subsequently we use bedload transport capacity calculations and climate data to assess their relative impact on the system evolution over the last 25 years. From the historical DEMs we find considerable aggradation of the river bed (up to 5 meters) since the onset of flow abstraction in 1963. Rapid and widespread aggradation however did not commence until the onset of glacier retreat in the late 1980s and the dry and notably warm years of the early 1990s. This aggradation coincided with an increase in sediment supply, although it accounts for only c. 25% of supplied material, the remainder was transferred through the studied reaches. Flow abstraction reduces transport capacity by an order of magnitude but the residual transport rates are close to sediment supply rates, which is why significant transport remains. However, the reduction in transport capacity due to direct human impacts in basin hydrology (flow abstraction) makes the system much more sensitive to changes in climate-driven hydrological variability and climate induced changes in intake management and sediment supply rates. This was exemplified by an increasingly strong climate (winter precipitation and summer temperature) influence on the delivery of glacially derived sediment.

  14. The effect of partial portal decompression on portal blood flow and effective hepatic blood flow in man: a prospective study.

    PubMed

    Rosemurgy, A S; McAllister, E W; Godellas, C V; Goode, S E; Albrink, M H; Fabri, P J

    1995-12-01

    With the advent of transjugular intrahepatic porta-systemic stent shunt and the wider application of the surgically placed small diameter prosthetic H-graft portacaval shunt (HGPCS), partial portal decompression in the treatment of portal hypertension has received increased attention. The clinical results supporting the use of partial portal decompression are its low incidence of variceal rehemorrhage due to decreased portal pressures and its low rate of hepatic failure, possibly due to maintenance of blood flow to the liver. Surprisingly, nothing is known about changes in portal hemodynamics and effective hepatic blood flow following partial portal decompression. To prospectively evaluate changes in portal hemodynamics and effective hepatic blood flow brought about by partial portal decompression, the following were determined in seven patients undergoing HGPCS: intraoperative pre- and postshunt portal vein pressures and portal vein-inferior vena cava pressure gradients, intraoperative pre- and postshunt portal vein flow, and pre- and postoperative effective hepatic blood flow. With HGPCS, portal vein pressures and portal vein-inferior vena cava pressure gradients decreased significantly, although portal pressures remained above normal. In contrast to the significant decreases in portal pressures, portal vein blood flow and effective hepatic blood flow do not decrease significantly. Changes in portal vein pressures and portal vein-inferior vena cava pressure gradients are great when compared to changes in portal vein flow and effective hepatic blood flow. Reduction of portal hypertension with concomitant maintenance of hepatic blood flow may explain why hepatic dysfunction is avoided following partial portal decompression.

  15. Comparison of pitch rate history effects on dynamic stall

    NASA Technical Reports Server (NTRS)

    Chandrasekhara, M. S.; Carr, Lawrence W.; Ahmed, S.

    1992-01-01

    Dynamic stall of an airfoil is a classic case of forced unsteady separated flow. Flow separation is brought about by large incidences introduced by the large amplitude unsteady pitching motion of an airfoil. One of the parameters that affects the dynamic stall process is the history of the unsteady motion. In addition, the problem is complicated by the effects of compressibility that rapidly appear over the airfoil even at low Mach numbers at moderately high angles of attack. Consequently, it is of interest to know the effects of pitch rate history on the dynamic stall process. This abstract compares the results of a flow visualization study of the problem with two different pitch rate histories, namely, oscillating airfoil motion and a linear change in the angle of attack due to a transient pitching motion.

  16. Optimization of Cooling Water Flow Rate in Nuclear and Thermal Power Plants Based on a Mathematical Model of Cooling Systems{sup 1}

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Murav’ev, V. P., E-mail: murval1@mail.ru; Kochetkov, A. V.; Glazova, E. G.

    A mathematical model and algorithms are proposed for automatic calculation of the optimum flow rate of cooling water in nuclear and thermal power plants with cooling systems of arbitrary complexity. An unlimited number of configuration and design variants are assumed with the possibility of obtaining a result for any computational time interval, from monthly to hourly. The structural solutions corresponding to an optimum cooling water flow rate can be used for subsequent engineering-economic evaluation of the best cooling system variant. The computerized mathematical model and algorithms make it possible to determine the availability and degree of structural changes for themore » cooling system in all stages of the life cycle of a plant.« less

  17. Very high pressure liquid chromatography using fully porous particles: quantitative analysis of fast gradient separations without post-run times.

    PubMed

    Stankovich, Joseph J; Gritti, Fabrice; Stevenson, Paul G; Beaver, Lois Ann; Guiochon, Georges

    2014-01-10

    Using a column packed with fully porous particles, four methods for controlling the flow rates at which gradient elution runs are conducted in very high pressure liquid chromatography (VHPLC) were tested to determine whether reproducible thermal conditions could be achieved, such that subsequent analyses would proceed at nearly the same initial temperature. In VHPLC high flow rates are achieved, producing fast analyses but requiring high inlet pressures. The combination of high flow rates and high inlet pressures generates local heat, leading to temperature changes in the column. Usually in this case a post-run time is input into the analytical method to allow the return of the column temperature to its initial state. An alternative strategy involves operating the column without a post-run equilibration period and maintaining constant temperature variations for subsequent analysis after conducting one or a few separations to bring the column to a reproducible starting temperature. A liquid chromatography instrument equipped with a pressure controller was used to perform constant pressure and constant flow rate VHPLC separations. Six replicate gradient separations of a nine component mixture consisting of acetophenone, propiophenone, butyrophenone, valerophenone, hexanophenone, heptanophenone, octanophenone, benzophenone, and acetanilide dissolved in water/acetonitrile (65:35, v/v) were performed under various experimental conditions: constant flow rate, two sets of constant pressure, and constant pressure operation with a programmed flow rate. The relative standard deviations of the response factors for all the analytes are lower than 5% across the methods. Programming the flow rate to maintain a fairly constant pressure instead of using instrument controlled constant pressure improves the reproducibility of the retention times by a factor of 5, when plotting the chromatograms in time. Copyright © 2013 Elsevier B.V. All rights reserved.

  18. Effort of breathing in children receiving high-flow nasal cannula.

    PubMed

    Rubin, Sarah; Ghuman, Anoopindar; Deakers, Timothy; Khemani, Robinder; Ross, Patrick; Newth, Christopher J

    2014-01-01

    High-flow humidified nasal cannula is often used to provide noninvasive respiratory support in children. The effect of high-flow humidified nasal cannula on effort of breathing in children has not been objectively studied, and the mechanism by which respiratory support is provided remains unclear. This study uses an objective measure of effort of breathing (Pressure. Rate Product) to evaluate high-flow humidified nasal cannula in critically ill children. Prospective cohort study. Quaternary care free-standing academic children's hospital. ICU patients younger than 18 years receiving high-flow humidified nasal cannula or whom the medical team planned to extubate to high-flow humidified nasal cannula within 72 hours of enrollment. An esophageal pressure monitoring catheter was placed to measure pleural pressures via a Bicore CP-100 pulmonary mechanics monitor. Change in pleural pressure (ΔPes) and respiratory rate were measured on high-flow humidified nasal cannula at 2, 5, and 8 L/min. ΔPes and respiratory rate were multiplied to generate the Pressure.Rate Product, a well-established objective measure of effort of breathing. Baseline Pes, defined as pleural pressure at end exhalation during tidal breathing, reflected the positive pressure generated on each level of respiratory support. Twenty-five patients had measurements on high-flow humidified nasal cannula. Median age was 6.5 months (interquartile range, 1.3-15.5 mo). Median Pressure,Rate Product was lower on high-flow humidified nasal cannula 8 L/min (median, 329 cm H2O·min; interquartile range, 195-402) compared with high-flow humidified nasal cannula 5 L/min (median, 341; interquartile range, 232-475; p = 0.007) or high-flow humidified nasal cannula 2 L/min (median, 421; interquartile range, 233-621; p < 0.0001) and was lower on high-flow humidified nasal cannula 5 L/min compared with high-flow humidified nasal cannula 2 L/min (p = 0.01). Baseline Pes was higher on high-flow humidified nasal cannula 8 L/min than on high-flow humidified nasal cannula 2 L/min (p = 0.03). Increasing flow rates of high-flow humidified nasal cannula decreased effort of breathing in children, with the most significant impact seen from high-flow humidified nasal cannula 2 to 8 L/min. There are likely multiple mechanisms for this clinical effect, including generation of positive pressure and washout of airway dead space.

  19. ASTM F739 method for testing the permeation resistance of protective clothing materials: critical analysis with proposed changes in procedure and test-cell design.

    PubMed

    Anna, D H; Zellers, E T; Sulewski, R

    1998-08-01

    ASTM (American Society for Testing and Materials) Method F739-96 specifies a test-cell design and procedures for measuring the permeation resistance of chemical protective clothing. Among the specifications are open-loop collection stream flow rates of 0.050 to 0.150 L/min for a gaseous medium. At elevated temperatures the test must be maintained within 1 degree C of the set point. This article presents a critical analysis of the effect of the collection stream flow rate on the measured permeation rate and on the temperature uniformity within the test cell. Permeation tests were conducted on four polymeric glove materials with 44 solvents at 25 degrees C. Flow rates > 0.5 L/min were necessary to obtain accurate steady-state permeation rate (SSPR) values in 25 percent of the tests. At the lower flow rates the true SSPR typically was underestimated by a factor of two or less, but errors of up to 33-fold were observed. No clear relationship could be established between the need for a higher collection stream flow rate and either the vapor pressure or the permeation rate of the solvent, but test results suggest that poor mixing within the collection chamber was a contributing factor. Temperature gradients between the challenge and collection chambers and between the bottom and the top of the collection chamber increased with the water-bath temperature and the collection stream flow rate. Use of a test cell modified to permit deeper submersion reduced the gradients to < or = 0.5 degrees C. It is recommended that all SSPR measurements include verification of the adequacy of the collection stream flow rate. For testing at nonambient temperatures, the modified test cell described here could be used to ensure temperature uniformity throughout the cell.

  20. Theoretical characteristics of two-dimensional supersonic control surfaces

    NASA Technical Reports Server (NTRS)

    Morrissette, Robert R; Oborny, Lester F

    1951-01-01

    The "Busemann second-order-approximation theory" for the pressure distribution over a two-dimensional airfoil in supersonic flow was used to determine some of the aerodynamic characteristics of uncambered symmetrical parabolic and double-wedge airfoils with leading-edge and trailing-edge flaps. The characteristics presented and discussed in this paper are: flap effectiveness factor, rate of change of hinge-moment coefficient with flap deflection, rate of change of the pitching-moment coefficient with flap deflection, rate of change of the pitching-moment coefficient about the mid chord with flap deflection, and the location of the center of pressure of the airfoil-flap combination.

  1. Gaseous slip flow analysis of a micromachined flow sensor for ultra small flow applications

    NASA Astrophysics Data System (ADS)

    Jang, Jaesung; Wereley, Steven T.

    2007-02-01

    The velocity slip of a fluid at a wall is one of the most typical phenomena in microscale gas flows. This paper presents a flow analysis considering the velocity slip in a capacitive micro gas flow sensor based on pressure difference measurements along a microchannel. The tangential momentum accommodation coefficient (TMAC) measurements of a particular channel wall in planar microchannels will be presented while the previous micro gas flow studies have been based on the same TMACs on both walls. The sensors consist of a pair of capacitive pressure sensors, inlet/outlet and a microchannel. The main microchannel is 128.0 µm wide, 4.64 µm deep and 5680 µm long, and operated under nearly atmospheric conditions where the outlet Knudsen number is 0.0137. The sensor was fabricated using silicon wet etching, ultrasonic drilling, deep reactive ion etching (DRIE) and anodic bonding. The capacitance change of the sensor and the mass flow rate of nitrogen were measured as the inlet-to-outlet pressure ratio was varied from 1.00 to 1.24. The measured maximum mass flow rate was 3.86 × 10-10 kg s-1 (0.019 sccm) at the highest pressure ratio tested. As the pressure difference increased, both the capacitance of the differential pressure sensor and the flow rate through the main microchannel increased. The laminar friction constant f sdot Re, an important consideration in sensor design, varied from the incompressible no-slip case and the mass sensitivity and resolution of this sensor were discussed. Using the current slip flow formulae, a microchannel with much smaller mass flow rates can be designed at the same pressure ratios.

  2. Evolution of Channels Draining Mount St. Helens: Linking Non-Linear and Rapid, Threshold Responses

    NASA Astrophysics Data System (ADS)

    Simon, A.

    2010-12-01

    The catastrophic eruption of Mount St. Helens buried the valley of the North Fork Toutle River (NFT) to a depth of up to 140 m. Initial integration of a new drainage network took place episodically by the “filling and spilling” (from precipitation and seepage) of depressions formed during emplacement of the debris avalanche deposit. Channel incision to depths of 20-30 m occurred in the debris avalanche and extensive pyroclastic flow deposits, and headward migration of the channel network followed, with complete integration taking place within 2.5 years. Downstream reaches were converted from gravel-cobble streams with step-pool sequences to smoothed, infilled channels dominated by sand-sized materials. Subsequent channel evolution was dominated by channel widening with the ratio of changes in channel width to changes in channel depth ranging from about 60 to 100. Widening resulted in significant adjustment of hydraulic variables that control sediment-transport rates. For a given discharge over time, flow depths were reduced, relative roughness increased and flow velocity and boundary shear stress decreased non-linearly. These changes, in combination with coarsening of the channel bed with time resulted in systematically reduced rates of degradation (in upstream reaches), aggradation (in downstream reaches) and sediment-transport rates through much of the 1990s. Vertical adjustments were, therefore, easy to characterize with non-linear decay functions with bed-elevation attenuating with time. An empirical model of bed-level response was then created by plotting the total dimensionless change in elevation against river kilometer for both initial and secondary vertical adjustments. High magnitude events generated from the generated from upper part of the mountain, however, can cause rapid (threshold) morphologic changes. For example, a rain-on-snow event in November 2006 caused up to 9 m of incision along a 6.5 km reach of Loowit Creek and the upper NFT. The event triggered a debris flow which cutoff tributary channels to Glacier Creek and redirected Step and Loowit Creeks thereby forcing enhanced flow volumes through the main channel. Very coarse, armored bed materials were mobilized allowing for deep incision into the substrate. Incision continues today at slower rates but it is again the lateral shifting and widening of the channels that is dominant. Low and moderate flows undercut the toe of 30 m-high pyroclastic flow deposits causing significant erosion. As the channel continues to widen incision will attenuate non-linearly. Channels such as the multiple Step Creek channels will coalesce as narrow ridges erode by undercutting and mass failure much as reaches of lower Loowit Creek did in the late 1980’s. The resulting enlarged and over-widened sections will then again (as in downstream reaches) have lowered transporting power.

  3. Variations from morning to afternoon of middle cerebral and umbilical artery blood flow, and fetal heart rate variability, and fetal characteristics in the normally developing fetus.

    PubMed

    Avitan, Tehila; Sanders, Ari; Brain, Ursula; Rurak, Dan; Oberlander, Tim F; Lim, Ken

    2018-05-01

    To determine if there are changes in maternal uterine blood flow, fetal brain blood flow, fetal heart rate variability, and umbilical blood flow between morning (AM) and afternoon (PM) in healthy, uncomplicated pregnancies. In this prospective study, 68 uncomplicated singleton pregnancies (mean 35 + 0.7 weeks gestation) underwent a standard observational protocol at both 08:00 (AM) and 13:30 (PM) of the same day. This protocol included Doppler measurements of uterine, umbilical, and fetal middle cerebral artery (MCA) volume flow parameters (flow, HR, peak systolic velocity [PSV], PI, and RI) followed by computerized cardiotocography. Standard descriptive statistics, χ 2 and t tests were used where appropriate. P < .05 was considered significant. A significant increase in MCA flow and MCA PSV was observed in the PM compared to the AM. This was accompanied by a fall in MCA resistance. Higher umbilical artery resistance indices were also observed in the PM compared to AM. In contrast, fetal heart rate characteristics, maternal uterine artery Doppler flow and resistance indices did not vary significantly between the AM and PM. In normal pregnancies, variations in fetal cerebral and umbilical blood flow parameters were observed between AM and PM independent of other fetal movements or baseline fetal heart rate. In contrast, uterine flow parameters remained stable across the day. These findings may have implications for the use of serial Doppler parameters used to guide clinical management in high-risk pregnancies. © 2017 Wiley Periodicals, Inc.

  4. Characterization of the Dynamic Pressure Response of Fuels in Microchannels

    NASA Astrophysics Data System (ADS)

    Haendler, Brenda; Pisano, Albert; Liepmann, Dorian

    2004-11-01

    In order to create a self-pumping fuel vaporization and delivery systems for a MEMS rotary engine power system, the dynamic pressure response due to phase eruption of fuels in micro channels must be characterized. Testing is done using micro channels with diameters the same order of magnitude as the critical bubble radius, a constant mass flow rate syringe pump, and a steady heat source. Pressure changes in the micro channel due to the periodic movement of the phase change meniscus are measured for a variety of flow conditions. A discrete Fourier transform is performed on the data to determine the dominant frequencies in the signal. Critical trends are discussed comparing both the frequency and the amplitude of the pressure spikes for a variety of temperatures and flow rates. The results presented on the trends in the pressure signature due to phase eruption for fuels are then related back to the fuel delivery system, which is using a nozzle-diffuser design to accomplish positive flow rectification given the periodic pressure condition at the phase eruption interface.

  5. Comparative evaluation of the effects of casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) and xylitol-containing chewing gum on salivary flow rate, pH and buffering capacity in children: An in vivo study.

    PubMed

    Hegde, Rahul J; Thakkar, Janhavi B

    2017-01-01

    This study aimed to compare and evaluate the changes in the salivary flow rate, pH, and buffering capacity before and after chewing casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) and xylitol-containing chewing gums in children. Sixty children aged between 8 and 12 years were selected for the study. They were randomly divided into Group 1 (CPP-ACP chewing gum) and Group 2 (xylitol-containing chewing gum) comprising thirty children each. Unstimulated and stimulated saliva samples at 15 and 30 min interval were collected from all children. All the saliva samples were estimated for salivary flow rate, pH, and buffering capacity. Significant increase in salivary flow rate, pH, and buffering capacity from baseline to immediately after spitting the chewing gum was found in both the study groups. No significant difference was found between the two study groups with respect to salivary flow rate and pH. Intergroup comparison indicated a significant increase in salivary buffer capacity in Group 1 when compared to Group 2. Chewing gums containing CPP-ACP and xylitol can significantly increase the physiochemical properties of saliva. These physiochemical properties of saliva have a definite relation with caries activity in children.

  6. Coulomb-coupled quantum-dot thermal transistors

    NASA Astrophysics Data System (ADS)

    Zhang, Yanchao; Yang, Zhimin; Zhang, Xin; Lin, Bihong; Lin, Guoxing; Chen, Jincan

    2018-04-01

    A quantum-dot thermal transistor consisting of three Coulomb-coupled quantum dots coupled to the respective electronic reservoirs by tunnel contacts is established. The heat flows through the collector and emitter can be controlled by the temperature of the base. It is found that a small change in the base heat flow can induce a large heat flow change in the collector and emitter. The huge amplification factor can be obtained by optimizing the Coulomb interaction between the collector and the emitter or by decreasing the tunneling rate at the base. The proposed quantum-dot thermal transistor may open up potential applications in low-temperature solid-state thermal circuits at the nanoscale.

  7. TI-59 helps predict IPRs for gravel-packed gas wells

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Capdevielle, W.C.

    The inflow performance relationship (IPR) is an important tool for reservoir and production engineers. It helps optimize completion, tubing, gas lift, and storm choke design. It facilitates accurate rate predictions that can be used to evaluate field development decisions. The IPR is the first step of the systems analysis that translates reservoir rock and fluid parameters into predictable flow rates. Use of gravel packing for sand control complicates the calculation that predicts a well's IPR curve, particularly in gas wells where high velocities in the formation and through gravel-filled perforation tunnels can cause turbulent flow. The program presented in thismore » article calculates the pressure drop and the flowing bottomhole pressures at varying flow rates for gravel-packed gas wells. The program was written for a Texas Instruments TI-59 programmable calculator with a PC-100 printer. Program features include: Calculations for in-casing gravel packs, open-hole gravel packs, or ungravel packed wells. Program prompts for the required data variables. Easy change of data values to run new cases. Calculates pressures for an unlimited number of flow rates. Results show the total pressure drop and the relative magnitude of its components.« less

  8. Numerical Simulation of Desulfurization Behavior in Gas-Stirred Systems Based on Computation Fluid Dynamics-Simultaneous Reaction Model (CFD-SRM) Coupled Model

    NASA Astrophysics Data System (ADS)

    Lou, Wentao; Zhu, Miaoyong

    2014-10-01

    A computation fluid dynamics-simultaneous reaction model (CFD-SRM) coupled model has been proposed to describe the desulfurization behavior in a gas-stirred ladle. For the desulfurization thermodynamics, different models were investigated to determine sulfide capacity and oxygen activity. For the desulfurization kinetic, the effect of bubbly plume flow, as well as oxygen absorption and oxidation reactions in slag eyes are considered. The thermodynamic and kinetic modification coefficients are proposed to fit the measured data, respectively. Finally, the effects of slag basicity and gas flow rate on the desulfurization efficiency are investigated. The results show that as the interfacial reactions (Al2O3)-(FeO)-(SiO2)-(MnO)-[S]-[O] simultaneous kinetic equilibrium is adopted to determine the oxygen activity, and the Young's model with the modification coefficient R th of 1.5 is adopted to determine slag sulfide capacity, the predicted sulfur distribution ratio LS agrees well with the measured data. With an increase of the gas blowing time, the predicted desulfurization rate gradually decreased, and when the modification parameter R k is 0.8, the predicted sulfur content changing with time in ladle agrees well with the measured data. If the oxygen absorption and oxidation reactions in slag eyes are not considered in this model, then the sulfur removal rate in the ladle would be overestimated, and this trend would become more obvious with an increase of the gas flow rate and decrease of the slag layer height. With the slag basicity increasing, the total desulfurization ratio increases; however, the total desulfurization ratio changes weakly as the slag basicity exceeds 7. With the increase of the gas flow rate, the desulfurization ratio first increases and then decreases. When the gas flow rate is 200 NL/min, the desulfurization ratio reaches a maximum value in an 80-ton gas-stirred ladle.

  9. The flow structure of jets from transient sources and implications for modeling short-duration explosive volcanic eruptions

    NASA Astrophysics Data System (ADS)

    Chojnicki, K. N.; Clarke, A. B.; Adrian, R. J.; Phillips, J. C.

    2014-12-01

    We used laboratory experiments to examine the rise process in neutrally buoyant jets that resulted from an unsteady supply of momentum, a condition that defines plumes from discrete Vulcanian and Strombolian-style eruptions. We simultaneously measured the analog-jet discharge rate (the supply rate of momentum) and the analog-jet internal velocity distribution (a consequence of momentum transport and dilution). Then, we examined the changes in the analog-jet velocity distribution over time to assess the impact of the supply-rate variations on the momentum-driven rise dynamics. We found that the analog-jet velocity distribution changes significantly and quickly as the supply rate varied, such that the whole-field distribution at any instant differed considerably from the time average. We also found that entrainment varied in space and over time with instantaneous entrainment coefficient values ranging from 0 to 0.93 in an individual unsteady jet. Consequently, we conclude that supply-rate variations exert first-order control over jet dynamics, and therefore cannot be neglected in models without compromising their capability to predict large-scale eruption behavior. These findings emphasize the fundamental differences between unsteady and steady jet dynamics, and show clearly that: (i) variations in source momentum flux directly control the dynamics of the resulting flow; (ii) impulsive flows driven by sources of varying flux cannot reasonably be approximated by quasi-steady flow models. New modeling approaches capable of describing the time-dependent properties of transient volcanic eruption plumes are needed before their trajectory, dilution, and stability can be reliably computed for hazards management.

  10. Dynamic control of gold nanoparticle morphology in a microchannel flow reactor by glucose reduction in aqueous sodium hydroxide solution.

    PubMed

    Ishizaka, Takayuki; Ishigaki, Atsushi; Kawanami, Hajime; Suzuki, Akira; Suzuki, Toshishige M

    2012-02-01

    Continuous flow synthesis of gold nanoparticles was demonstrated using a microchannel reactor with glucose reduction in aqueous alkaline medium. Particle size, morphology, and visual/optical properties of the dispersion liquid were controlled dynamically by tuning of the rate of NaOH addition. Characteristic star-like nanoparticles formed spontaneously as a quasi-stable state, but they changed the morphology to round shape and showed spectral change over time. Copyright © 2011 Elsevier Inc. All rights reserved.

  11. Cough-Associated Changes in CSF Flow in Chiari I Malformation Evaluated by Real-Time MRI.

    PubMed

    Bhadelia, R A; Patz, S; Heilman, C; Khatami, D; Kasper, E; Zhao, Y; Madan, N

    2016-05-01

    Invasive pressure studies have suggested that CSF flow across the foramen magnum may transiently decrease after coughing in patients with symptomatic Chiari I malformation. The purpose of this exploratory study was to demonstrate this phenomenon noninvasively by assessing CSF flow response to coughing in symptomatic patients with Chiari I malformation by using MR pencil beam imaging and to compare the response with that in healthy participants. Eight symptomatic patients with Chiari I malformation and 6 healthy participants were studied by using MR pencil beam imaging with a temporal resolution of ∼50 ms. Patients and healthy participants were scanned for 90 seconds (without cardiac gating) to continuously record cardiac cycle-related CSF flow waveforms in real-time during resting, coughing, and postcoughing periods. CSF flow waveform amplitude, CSF stroke volume, and CSF flow rate (CSF Flow Rate = CSF Stroke Volume × Heart Rate) in the resting and immediate postcoughing periods were determined and compared between patients and healthy participants. There was no significant difference in CSF flow waveform amplitude, CSF stroke volume, and the CSF flow rate between patients with Chiari I malformation and healthy participants during rest. However, immediately after coughing, a significant decrease in CSF flow waveform amplitude (P < .001), CSF stroke volume (P = .001), and CSF flow rate (P = .001) was observed in patients with Chiari I malformation but not in the healthy participants. Real-time MR imaging noninvasively showed a transient decrease in CSF flow across the foramen magnum after coughing in symptomatic patients with Chiari I malformation, a phenomenon not seen in healthy participants. Our results provide preliminary evidence that the physiology-based imaging method used here has the potential to be an objective clinical test to differentiate symptomatic from asymptomatic patients with Chiari I malformation. © 2016 by American Journal of Neuroradiology.

  12. Visually evoked changes in the rat retinal blood flow measured with Doppler optical coherence tomography (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Tan, Bingyao; Mason, Erik; MacLellan, Ben; Bizheva, Kostadinka

    2017-02-01

    Visually evoked changes of retinal blood flow can serve as an important research tool to investigate eye disease such as glaucoma and diabetic retinopathy. In this study we used a combined, research-grade, high-resolution Doppler OCT+ERG system to study changes in the retinal blood flow (RBF) and retinal neuronal activity in response to visual stimuli of different intensities, durations and type (flicker vs single flash). Specifically, we used white light stimuli of 10 ms and 200 ms single flash, 1s and 2s for flickers stimuli of 20% duty cycle. The study was conducted in-vivo in pigmented rats. Both single flash (SF) and flicker stimuli caused increase in the RBF. The 10 ms SF stimulus did not generate any consistent measurable response, while the 200 ms SF of the same intensity generated 4% change in the RBF peaking at 1.5 s after the stimulus onset. Single flash stimuli introduced 2x smaller change in RBF and 30% earlier RBF peak response compared to flicker stimuli of the same intensity and duration. Doubling the intensity of SF or flicker stimuli increased the RBF peak magnitude by 1.5x. Shortening the flicker stimulus duration by 2x increased the RBF recovery rate by 2x, however, had no effect on the rate of RBF change from baseline to peak.

  13. How kelp produce blade shapes suited to different flow regimes: A new wrinkle.

    PubMed

    Koehl, M A R; Silk, W K; Liang, H; Mahadevan, L

    2008-12-01

    Many species of macroalgae have flat, strap-like blades in habitats exposed to rapidly flowing water, but have wide, ruffled "undulate" blades at protected sites. We used the giant bull kelp, Nereocystis luetkeana, to investigate how these ecomorphological differences are produced. The undulate blades of N. luetkeana from sites with low flow remain spread out and flutter erratically in moving water, thereby not only enhancing interception of light, but also increasing drag. In contrast, strap-like blades of kelp from habitats with rapid flow collapse into streamlined bundles and flutter at low amplitude in flowing water, thus reducing both drag and interception of light. Transplant experiments in the field revealed that shape of the blade in N. luetkeana is a plastic trait. Laboratory experiments in which growing blades from different sites were subjected to tensile forces that mimicked the hydrodynamic drag experienced by blades in different flow regimes showed that change in shape is induced by mechanical stress. During growth experiments in the field and laboratory, we mapped the spatial distribution of growth in both undulate and strap-like blades to determine how these different morphologies were produced. The highest growth rates occur near the proximal ends of N. luetkeana blades of both morphologies, but the rates of transverse growth of narrow, strap-like blades are lower than those of wide, undulate blades. If rates of longitudinal growth at the edges of a blade exceed the rate of longitudinal growth along the midline of the blade, ruffles along the edges of the blade are produced by elastic buckling. In contrast, flat blades are produced when rates of longitudinal growth are similar across the width of a blade. Because ruffles are the result of elastic buckling, a compliant undulate N. luetkeana blade can easily be pushed into different configurations (e.g., the wavelengths of the ruffles along the edges of the blade can change, and the whole blade can twist into left- and right-handed helicoidal shapes), which may enhance movements of the blade in flowing water that reduce self-shading and increase mass exchange along blade surfaces.

  14. The experimental study of matching between centrifugal compressor impeller and diffuser

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tamaki, H.; Nakao, H.; Saito, M.

    1999-01-01

    the centrifugal compressor for a marine use turbocharger with its design pressure ratio of 3.2 was tested with a vaneless diffuser and various vaned diffusers. Vaned diffusers were chosen to cover impeller operating range as broad as possible. The analysis of the static pressure ratio in the impeller and the diffusing system, consisting of the diffuser and scroll, showed that there were four possible combinations of characteristics of impeller pressure ratio and diffusing system pressure ratio. The flow rate, Q{sub P}, where the impeller achieved maximum static pressure ratio, was surge flow rate of the centrifugal compressor determined by themore » critical flow rate. In order to operate the compressor at a rate lower than Q{sub P}, the diffusing system, whose pressure recovery factor was steep negative slope near Q{sub P}, was needed. When the diffuser throat area was less than a certain value, the compressor efficiency deteriorated; however, the compressor stage pressure ratio was almost constant. In this study, by reducing the diffuser throat area, the compressor could be operated at a flow rate less than 40% of its design flow rate. Analysis of the pressure ratio in the impeller and diffusing systems at design and off-design speeds showed that the irregularities in surge line occurred when the component that controlled the negative slope on the compressor stage pressure ratio changed.« less

  15. Multicenter, prospective, comparative cohort study evaluating the efficacy and safety of alfuzosin 10 mg with regard to blood pressure in men with lower urinary tract symptoms suggestive of benign prostatic hyperplasia with or without antihypertensive medications.

    PubMed

    Zhang, Li Tao; Lee, Sung Won; Park, Kwangsung; Chung, Woo Sik; Kim, Sae Woong; Hyun, Jae Seog; Moon, Doo Geon; Yang, Sang-Kuk; Ryu, Ji Kan; Yang, Dae Yul; Moon, Ki Hak; Min, Kweon Sik; Park, Jong Kwan

    2015-01-01

    The objective of this study was to assess the efficacy and safety of alfuzosin 10 mg monotherapy or combined antihypertensive medication on blood pressure (BP) in patients with lower urinary tract symptoms suggestive of benign prostatic hyperplasia (BPH/LUTS) with or without antihypertensive medication. This was a 3-month, multicenter, randomized, open-label study in 335 patients aged ≥45 years with a clinical diagnosis of BPH/LUTS by medical history and clinical examination, a total International Prostatic Symptom Score (IPSS) ≥8 points, a maximum flow rate >5 mL/sec and ≤15 mL/sec, and a voided volume ≥120 mL. Eligible subjects were randomized to receive alfuzosin 10 mg as monotherapy (group 1) or alfuzosin 10 mg + antihypertensive combination therapy (group 2). Based on baseline BP and hypertensive history with or without antihypertensive medications at first medical examination, group 1 was divided into two subgroups of normotensive and untreated hypertensive patients, and group 2 into two subgroups of controlled hypertensive and uncontrolled hypertensive patients. The primary study outcomes were change in IPSS, BP, and heart rate from baseline. Secondary outcomes were change in IPSS-quality of life score, maximum flow rate, average flow rate, voided volume, and post-voided volume. The overall BP change was not significantly different between groups 1 and 2 (systolic BP, P=0.825; diastolic BP, P>0.999). In patients with uncontrolled or untreated hypertension, alfuzosin 10 mg alone or combined with antihypertensive therapy significantly decreased systolic and diastolic BP. The mean difference in total IPSS and IPSS-quality of life scores from baseline between groups 1 and 2 was 0.45 (95% CI: -1.26, 2.16) and 0.12 (95% CI: -0.21, 0.45), respectively (both P>0.05). Maximum flow rate, average flow rate, voided volume, and post-voided volume at endpoint were numerically, but not significantly, changed from baseline (all P>0.05). This study shows that alfuzosin 10 mg is effective and well tolerated in patients with BPH/LUTS with or without antihypertensive medications. However, in patients with uncontrolled or untreated hypertension, alfuzosin 10 mg alone or in combination with antihypertensive medication appears to decrease systolic and diastolic BP, and these patients should be warned about a decrease in BP on initiation of therapy.

  16. A new approach to monitoring spatial distribution and dynamics of wetlands and associated flows of Australian Great Artesian Basin springs using QuickBird satellite imagery

    NASA Astrophysics Data System (ADS)

    White, Davina C.; Lewis, Megan M.

    2011-09-01

    SummaryThis study develops an expedient digital mapping technique using Very High Resolution satellite imagery to monitor the temporal response of permanent wetland vegetation to changes in spring flow rates from the Australian Great Artesian Basin at Dalhousie Springs Complex, South Australia. Three epochs of QuickBird satellite multispectral imagery acquired between 2006 and 2010 were analysed using the Normalised Difference Vegetation Index (NDVI). A regression of 2009 NDVI values against vegetation cover from field botanical survey plots provided a relationship of increasing NDVI with increased vegetation cover ( R2 = 0.86; p < 0.001). On the basis of this relationship a vegetation threshold was determined (NDVI ⩾ 0.35), which discriminated perennial and ephemeral wetland vegetation from surrounding dryland vegetation in the imagery. The extent of wetlands for the entire Dalhousie Springs Complex mapped from the imagery increased from 607 ha in December 2006 to 913 ha in May 2009 and 1285 ha in May 2010. Comparison of the three NDVI images showed considerable localised change in wetland vegetation greenness, distribution and extent in response to fires, alien vegetation removal, rainfall and fluctuations in spring flow. A strong direct relationship ( R2 = 0.99; p < 0.001) was exhibited between spring flow rate and the area of associated wetland vegetation for eight individual springs. This relationship strongly infers that wetland area is an indicator of spring flow and can be used for monitoring purposes. This method has the potential to determine the sensitivity of spring wetland vegetation extent and distribution to associated changes in spring flow rates due to land management and aquifer extractions. Furthermore, this approach is timely and provides reliable and repeatable monitoring, particularly needed given the projected increased demand for groundwater extractions from the GAB for mining operations.

  17. Sediment Transport Dynamics and Bedform Evolution During Unsteady Flows

    NASA Astrophysics Data System (ADS)

    Hu, H.; Parsons, D. R.; Ockelford, A.; Hardy, R. J.; Ashworth, P. J.; Best, J.

    2016-12-01

    Dunes are ubiquitous features in sand bed rivers and estuaries, and their formation, growth and kinematics play a dominant role in boundary flow structure, flow resistance and sediment transport processes. However, bedform evolution and dynamics during the rising/falling limb of a flood wave remain poorly understood. Herein, we report on a series of flume experiments, undertaken at the University of Hull's Total Environment Simulator flume/wave tank facility, with imposed flow variations and different hydrographs: i) a sudden (shock) change, ii) a fast flood wave and iii) a slow flood wave. Our analysis shows that, because of changes of sediment transport mechanisms with discharge, the sediment flux rather than bedform migration rate is a more appropriate parameter to relate to transport stage. This is particularly the case during bedload transport dominated periods at lower flow discharge, where a strong power law relationship was detected. In terms of varying processes across the hydrograph limbs, bedform evolution during the rising limb is dominated not only by bedform amalgamation but also by the washing out of smaller-scale bedforms. Furthermore, bedform growth is independent of the rising rate of the hydrograph limb, while evolution of bedform decay is affected by the rate of discharge decrease. This results in an anticlockwise hysteresis between transport stage and total flux was found in fast wave experiment, indicating a significant role of the change in sediment transport mechanisms on bedform evolution. Moreover, analysis on the variation of deformation fraction (F, ratio of the deformation flux to the total bed material flux) suggests that net degradation of the bed enhances bedform deformation and leads to a higher F ( 0.65). This work extends our knowledge on how dunes generate and develop under variable flows and has begun to explore how variations in transport stage can be coupled with the variation in sediment transport mechanisms, and/or sediment supply which can help improve the modelling of sediment transport processes.

  18. Hydrologic Connectivity and Land Use Effects on Sediment Accumulation on Stream Floodplains of the Savannah River Site, South Carolina.

    NASA Astrophysics Data System (ADS)

    Eddy, J.; Yeager, K. M.; Barton, C.; Phillips, J. D.

    2016-12-01

    Natural sediment accumulation on floodplains is important to maintain water quality of streams, to support regional biodiversity as an ecotone between aquatic and terrestrial environments, and to serve as a sink for organic and inorganic carbon. Recent research suggests that land use and hydrologic connectivity play important roles in determining rates of sediment accumulation. This study hypothesizes that changes in hydrologic connectivity have a greater impact on sediment accumulation rates than changes in land use. Nine sediment cores from seven sub-basins were taken from the Savannah River Site, South Carolina, and processed for grain-size, radioisotope dating, particulate organic carbon (POC), and microscopy. Stratigraphic columns were created for all nine cores. Extensive historical records, aerial, and satellite imagery are used to identify anthropogenic disturbances which may have influenced rates of sediment accumulation, as well as to calculate the percentage of natural vegetation in 1951 and 2014. Grain-size analysis and microscopy indicate that the majority of sediment studied is sand-sized quartz; changes in grain-size classification is used to indicate potential differences in sediment sources. LiDAR and field survey data were used to identify 251 stream flow impediments that potentially affect hydrologic connectivity. Results from radioisotope dating and POC have been used to calculate sediment mass accumulation rates (SMAR; g cm-2 y-1) and linear accumulation rates (LAR; cm y-1) for each of the cores. Preliminary findings show that plots of SMAR versus the number of flow impediments have steeper slopes than plots of SMAR versus the percent difference in vegetation (from 1951 to 2014). This signifies that flow impediments, as a proxy for hydrologic connectivity, have a stronger effect on sediment accumulation rates than changes in land use. This knowledge can help future stream restoration efforts by focusing resources to more efficiently attain stated goals.

  19. The rate of rise, fall and gravity spreading at Siahou diapir (Southern Iran)

    NASA Astrophysics Data System (ADS)

    Aftabi, P.; Roustaie, M.

    2009-04-01

    InSAR imaging can be used for extracting three dimensional information of the diapirs surface by using the phase part of the radar signal. We used InSAR to examine the cumulative surface deformation between 920706 to 060518, in a 10×10 km region surrounding the salt diapir at Kuh-e-Namak Siahou. The interferograms span periods was between 35-70 and 1248 days. Images acquired in 12 increments provided by ESA. This technique used here involves computation and subsequent combinations of interferometric phase gradient maps were used for mapping the salt flow deformation in the Zagros. Kuh-e-Namak Siahou is one of the salt extrusions currently active in the Zagros range in Iran. Salt rises from a mother salt horizon about 4 km deep and extruded as a dome with glacier on the surface. The geometry and inferred flow pattern of the salt changed between the increments, emphasizing that the extrusion rate and gravity spreading is not steady. Elevations in the salt mountain range from 1000 to 1640 meters and the displacements exceed to 20cm per year . Our InSAR study(Fig1) suggest that the dimensions and velocity of the salt movements are changing between 2 to 20mm per year(-0.7 to0.59 mm per day).The rate of surface dissolution changed between 2 to 4 cm a-1, and its rate of rise out of its orifice at 0 to 200 mm per year. The InSAR study suggest that the vigorous salt extrusion in Siahou is probably active.The deep source probably rise at a similar rates in the past but it fall in the time of InSAR study. The rate of fall was 260 mm per year(for 14 years). The InSAR images suggest that salt extrusion in Siahou flow laterally at rate 20-25 mm per year and the namakiers felt at -2 mm per month. The InSAR results indicated concentric and radial flow in the diapir from a central point at summit and spreading glaciers in sideways.Phase differences measured in our interferograms generally in the range of 0-260 mm/yr(-260 mm) within the studied period, with exceptional high rates that exceed 50 mm/yr in diapir Siahou. Comparison of our InSAR observations with models suggest a similarity in the strain pattern in the model and prototype. Our observations also show that in certain locations of Zagros, movements appear to be structurally controlled by salt flow, and diapirism. This report will improve our understanding on how the salt diapirs work and our capability to predict future flow and the associated hazards for storages in salt and provides the first direct, spatially resolved, measurement of ongoing flow of salt. Key words: Salt tectonics,InSAR,Monitoring,Iran,Zagros,Salt diapir,salt kinematics, Zagros fold-thrust belt, Hormuz salt, analogue modelling,salt extrusion, crustal shortening

  20. A compact model for electroosmotic flows in microfluidic devices

    NASA Astrophysics Data System (ADS)

    Qiao, R.; Aluru, N. R.

    2002-09-01

    A compact model to compute flow rate and pressure in microfluidic devices is presented. The microfluidic flow can be driven by either an applied electric field or a combined electric field and pressure gradient. A step change in the ζ-potential on a channel wall is treated by a pressure source in the compact model. The pressure source is obtained from the pressure Poisson equation and conservation of mass principle. In the proposed compact model, the complex fluidic network is simplified by an electrical circuit. The compact model can predict the flow rate, pressure distribution and other basic characteristics in microfluidic channels quickly with good accuracy when compared to detailed numerical simulation. Using the compact model, fluidic mixing and dispersion control are studied in a complex microfluidic network.

  1. Locations of ectopic beats coincide with spatial gradients of NADH in a regional model of low-flow reperfusion.

    PubMed

    Kay, Matthew; Swift, Luther; Martell, Brian; Arutunyan, Ara; Sarvazyan, Narine

    2008-05-01

    We studied the origins of ectopic beats during low-flow reperfusion after acute regional ischemia in excised rat hearts. The left anterior descending coronary artery was cannulated. Perfusate was delivered to the cannula using an high-performance liquid chromatography pump. This provided not only precise control of flow rate but also avoided mechanical artifacts associated with vessel occlusion and deocclusion. Optical mapping of epicardial transmembrane potential served to identify activation wavefronts. Imaging of NADH fluorescence was used to quantify local ischemia. Our experiments suggest that low-flow reperfusion of ischemic myocardium leads to a highly heterogeneous ischemic substrate and that the degree of ischemia between adjacent patches of tissue changes in time. In contrast to transient ectopic activity observed during full-flow reperfusion, persistent ectopic arrhythmias were observed during low-flow reperfusion. The origins of ectopic beats were traceable to areas of high spatial gradients of changes in NADH fluorescence caused by low-flow reperfusion.

  2. Uncertainty Management in Urban Water Engineering Adaptation to Climate Change

    EPA Science Inventory

    Current water resource planning and engineering assume a stationary climate, in which the observed historical water flow rate and water quality variations are often used to define the technical basis. When the non-stationarity is considered, however, climate change projection co...

  3. Causes of distal volcano-tectonic seismicity inferred from hydrothermal modeling

    USGS Publications Warehouse

    Coulon, Cecile A.; Hsieh, Paul A.; White, Randall A.; Lowenstern, Jacob B.; Ingebritsen, Steven E.

    2017-01-01

    Distal volcano-tectonic (dVT) seismicity typically precedes eruption at long-dormant volcanoes by days to years. Precursory dVT seismicity may reflect magma-induced fluid-pressure pulses that intersect critically stressed faults. We explored this hypothesis using an open-source magmatic-hydrothermal code that simulates multiphase fluid and heat transport over the temperature range 0 to 1200 °C. We calculated fluid-pressure changes caused by a small (0.04 km3) intrusion and explored the effects of flow geometry (channelized vs. radial flow), magma devolatilization rates (0–15 kg/s), and intrusion depths (5 and 7.5 km, above and below the brittle-ductile transition). Magma and host-rock permeabilities were key controlling parameters and we tested a wide range of permeability (k) and permeability anisotropies (kh/kv), including k constant, k(z), k(T), and k(z, T, P) distributions, examining a total of ~ 1600 realizations to explore the relevant parameter space. Propagation of potentially causal pressure changes (ΔP ≥ 0.1 bars) to the mean dVT location (6 km lateral distance, 6 km depth) was favored by channelized fluid flow, high devolatilization rates, and permeabilities similar to those found in geothermal reservoirs (k ~ 10− 16 to 10− 13 m2). For channelized flow, magma-induced thermal pressurization alone can generate cases of ∆ P ≥ 0.1 bars for all permeabilities in the range 10− 16 to 10− 13 m2, whereas in radial flow regimes thermal pressurization causes ∆ P < 0.1 bars for all permeabilities. Changes in distal fluid pressure occurred before proximal pressure changes given modest anisotropies (kh/kv ~ 10–100). Invoking k(z,T,P) and high, sustained devolatilization rates caused large dynamic fluctuations in k and P in the near-magma environment but had little effect on pressure changes at the distal dVT location. Intrusion below the brittle-ductile transition damps but does not prevent pressure transmission to the dVT site.

  4. The effect of basal channels on oceanic ice-shelf melting

    NASA Astrophysics Data System (ADS)

    Millgate, Thomas; Holland, Paul R.; Jenkins, Adrian; Johnson, Helen L.

    2013-12-01

    The presence of ice-shelf basal channels has been noted in a number of Antarctic and Greenland ice shelves, but their impact on basal melting is not fully understood. Here we use the Massachusetts Institute of Technology general circulation model to investigate the effect of ice-shelf basal channels on oceanic melt rate for an idealized ice shelf resembling the floating tongue of Petermann Glacier in Greenland. The introduction of basal channels prevents the formation of a single geostrophically balanced boundary current; instead the flow is diverted up the right-hand (Coriolis-favored) side of each channel, with a return flow in the opposite direction on the left-hand side. As the prescribed number of basal channels is increased the mean basal melt rate decreases, in agreement with previous studies. For a small number of relatively wide channels the subice flow is found to be a largely geostrophic horizontal circulation. The reduction in melt rate is then caused by an increase in the relative contribution of weakly melting channel crests and keels. For a larger number of relatively narrow channels, the subice flow changes to a vertical overturning circulation. This change in circulation results in a weaker sensitivity of melt rates to channel size. The transition between the two regimes is governed by the Rossby radius of deformation. Our results explain why basal channels play an important role in regulating basal melting, increasing the stability of ice shelves.

  5. Urban base flow with low impact development

    USGS Publications Warehouse

    Bhaskar, Aditi; Hogan, Dianna M.; Archfield, Stacey A.

    2016-01-01

    A novel form of urbanization, low impact development (LID), aims to engineer systems that replicate natural hydrologic functioning, in part by infiltrating stormwater close to the impervious surfaces that generate it. We sought to statistically evaluate changes in a base flow regime because of urbanization with LID, specifically changes in base flow magnitude, seasonality, and rate of change. We used a case study watershed in Clarksburg, Maryland, in which streamflow was monitored during whole-watershed urbanization from forest and agricultural to suburban residential development using LID. The 1.11-km2 watershed contains 73 infiltration-focused stormwater facilities, including bioretention facilities, dry wells, and dry swales. We examined annual and monthly flow during and after urbanization (2004–2014) and compared alterations to nearby forested and urban control watersheds. We show that total streamflow and base flow increased in the LID watershed during urbanization as compared with control watersheds. The LID watershed had more gradual storm recessions after urbanization and attenuated seasonality in base flow. These flow regime changes may be because of a reduction in evapotranspiration because of the overall decrease in vegetative cover with urbanization and the increase in point sources of recharge. Precipitation that may once have infiltrated soil, been stored in soil moisture to be eventually transpired in a forested landscape, may now be recharged and become base flow. The transfer of evapotranspiration to base flow is an unintended consequence to the water balance of LID.

  6. Some applications of equilibrium thermodynamic properties to continuum gasdynamics

    NASA Technical Reports Server (NTRS)

    1976-01-01

    The speed of sound for the propagation of isentropic disturbances in a gas is developed, including corrections for chemical reaction. The term zero frequency is used to describe this isentropic limit sound speed; the term signifies that change in the gasdynamic variables are all very slow compared with the chemical rate changes in the gas. A faster, nonisentropic speed of propagation occurs for disturbances where the changes in gasdynamic variables are fast compared with the chemical rate changes. In the limit, this is known as the infinite frequency or frozen sound speed - the former term calling attention to the very high frequency of the disturbance, the latter term calling attention to the frozen character of the chemical reactions under such rapid changes of state. The true sound speed for a disturbance of finite frequency is shown to be between these two limits and is expressed in terms of the chemical relaxation time. The Riemann invariants that are useful in determining the changes in flow speed along characteristic directions in supersonic flow are derived in terms of integrations of acoustic impedance, and example results are given for air.

  7. Air change rates and interzonal flows in residences, and the need for multi-zone models for exposure and health analyses.

    PubMed

    Du, Liuliu; Batterman, Stuart; Godwin, Christopher; Chin, Jo-Yu; Parker, Edith; Breen, Michael; Brakefield, Wilma; Robins, Thomas; Lewis, Toby

    2012-12-12

    Air change rates (ACRs) and interzonal flows are key determinants of indoor air quality (IAQ) and building energy use. This paper characterizes ACRs and interzonal flows in 126 houses, and evaluates effects of these parameters on IAQ. ACRs measured using weeklong tracer measurements in several seasons averaged 0.73 ± 0.76 h(-1) (median = 0.57 h(-1), n = 263) in the general living area, and much higher, 1.66 ± 1.50 h(-1) (median = 1.23 h(-1), n = 253) in bedrooms. Living area ACRs were highest in winter and lowest in spring; bedroom ACRs were highest in summer and lowest in spring. Bedrooms received an average of 55 ± 18% of air from elsewhere in the house; the living area received only 26 ± 20% from the bedroom. Interzonal flows did not depend on season, indoor smoking or the presence of air conditioners. A two-zone IAQ model calibrated for the field study showed large differences in pollutant levels between the living area and bedroom, and the key parameters affecting IAQ were emission rates, emission source locations, air filter use, ACRs, interzonal flows, outdoor concentrations, and PM penetration factors. The single-zone models that are commonly used for residences have substantial limitations and may inadequately represent pollutant concentrations and exposures in bedrooms and potentially other environments other where people spend a substantial fraction of time.

  8. Air Change Rates and Interzonal Flows in Residences, and the Need for Multi-Zone Models for Exposure and Health Analyses

    PubMed Central

    Du, Liuliu; Batterman, Stuart; Godwin, Christopher; Chin, Jo-Yu; Parker, Edith; Breen, Michael; Brakefield, Wilma; Robins, Thomas; Lewis, Toby

    2012-01-01

    Air change rates (ACRs) and interzonal flows are key determinants of indoor air quality (IAQ) and building energy use. This paper characterizes ACRs and interzonal flows in 126 houses, and evaluates effects of these parameters on IAQ. ACRs measured using weeklong tracer measurements in several seasons averaged 0.73 ± 0.76 h−1 (median = 0.57 h−1, n = 263) in the general living area, and much higher, 1.66 ± 1.50 h−1 (median = 1.23 h−1, n = 253) in bedrooms. Living area ACRs were highest in winter and lowest in spring; bedroom ACRs were highest in summer and lowest in spring. Bedrooms received an average of 55 ± 18% of air from elsewhere in the house; the living area received only 26 ± 20% from the bedroom. Interzonal flows did not depend on season, indoor smoking or the presence of air conditioners. A two-zone IAQ model calibrated for the field study showed large differences in pollutant levels between the living area and bedroom, and the key parameters affecting IAQ were emission rates, emission source locations, air filter use, ACRs, interzonal flows, outdoor concentrations, and PM penetration factors. The single-zone models that are commonly used for residences have substantial limitations and may inadequately represent pollutant concentrations and exposures in bedrooms and potentially other environments other where people spend a substantial fraction of time. PMID:23235286

  9. [Rainfall effects on the sap flow of Hedysarum scoparium.

    PubMed

    Yang, Qiang; Zha, Than Shan; Jia, Xin; Qin, Shu Gao; Qian, Duo; Guo, Xiao Nan; Chen, Guo Peng

    2016-03-01

    In arid and semi-arid areas, plant physiological responses to water availability depend largely on the intensity and frequency of rain events. Knowledge on the responses of xerophytic plants to rain events is important for predicting the structure and functioning of dryland ecosystems under changing climate. The sap flow of Hedysarum scoparium in the Mu Us Sand Land was continuously measured during the growing season of 2012 and 2013. The objectives were to quantify the dynamics of sap flow under different weather conditions, and to examine the responses of sap flow to rain events of different sizes. The results showed that the daily sap flow rates of H. scoparium were lower on rainy days than on clear days. On clear days, the sap flow of H. scoparium showed a midday plateau, and was positively correlated with solar radiation and relative humidity. On rainy days, the sap flow fluctuated at low levels, and was positively correlated with solar radiation and air temperature. Rain events not only affected the sap flow on rainy days through variations in climatic factors (e.g., solar radiation and air temperature), but also affected post-rainfall sap flow velocities though changes in soil moisture. Small rain events (<20 mm) did not change the sap flow, whereas large rain events (>20 mm) significantly increased the sap flow on days following rainfall. Rain-wetted soil conditions not only resulted in higher sap flow velocities, but also enhanced the sensitivity of sap flow to solar radiation, vapor pressure deficit and air temperature.

  10. Effective regurgitant orifice area by the color Doppler flow convergence method for evaluating the severity of chronic aortic regurgitation. An animal study.

    PubMed

    Shiota, T; Jones, M; Yamada, I; Heinrich, R S; Ishii, M; Sinclair, B; Holcomb, S; Yoganathan, A P; Sahn, D J

    1996-02-01

    The aim of the present study was to evaluate dynamic changes in aortic regurgitant (AR) orifice area with the use of calibrated electromagnetic (EM) flowmeters and to validate a color Doppler flow convergence (FC) method for evaluating effective AR orifice area and regurgitant volume. In 6 sheep, 8 to 20 weeks after surgically induced AR, 22 hemodynamically different states were studied. Instantaneous regurgitant flow rates were obtained by aortic and pulmonary EM flowmeters balanced against each other. Instantaneous AR orifice areas were determined by dividing these actual AR flow rates by the corresponding continuous wave velocities (over 25 to 40 points during each diastole) matched for each steady state. Echo studies were performed to obtain maximal aliasing distances of the FC in a low range (0.20 to 0.32 m/s) and a high range (0.70 to 0.89 m/s) of aliasing velocities; the corresponding maximal AR flow rates were calculated using the hemispheric flow convergence assumption for the FC isovelocity surface. AR orifice areas were derived by dividing the maximal flow rates by the maximal continuous wave Doppler velocities. AR orifice sizes obtained with the use of EM flowmeters showed little change during diastole. Maximal and time-averaged AR orifice areas during diastole obtained by EM flowmeters ranged from 0.06 to 0.44 cm2 (mean, 0.24 +/- 0.11 cm2) and from 0.05 to 0.43 cm2 (mean, 0.21 +/- 0.06 cm2), respectively. Maximal AR orifice areas by FC using low aliasing velocities overestimated reference EM orifice areas; however, at high AV, FC predicted the reference areas more reliably (0.25 +/- 0.16 cm2, r = .82, difference = 0.04 +/- 0.07 cm2). The product of the maximal orifice area obtained by the FC method using high AV and the velocity time integral of the regurgitant orifice velocity showed good agreement with regurgitant volumes per beat (r = .81, difference = 0.9 +/- 7.9 mL/beat). This study, using strictly quantified AR volume, demonstrated little change in AR orifice size during diastole. When high aliasing velocities are chosen, the FC method can be useful for determining effective AR orifice size and regurgitant volume.

  11. Modeling and Simulation of Hydropower Station Diversion System's characteristic line method by introducing water head to flow feedback

    NASA Astrophysics Data System (ADS)

    Guangwen, Xu; Xi, Li; Ze, Yao

    2018-06-01

    To solve the damping problem of water hammer wave in the modeling method of water diversion system of hydropower station, this paper introduces the feedback regulation technology from head to flow, that is: A fixed water head is taken out for flow feedback, and the following conclusions are obtained through modeling and simulation. Adjusting the feedback coefficient F of the water head to the flow rate can change the damping characteristic of the system, which can simulate the attenuation process of the water shock wave in the true water diversion pipeline. Even if a small feedback coefficient is introduced, the damping effect of the system is very obvious, but it has little effect on the amplitude of the first water shock wave after the transition process. Therefore, it is feasible and reasonable to introduce water head to flow rate feedback coefficient F in hydraulic turbine diversion system.

  12. Carbon assimilation and transfer through kelp forests in the NE Atlantic is diminished under a warmer ocean climate.

    PubMed

    Pessarrodona, Albert; Moore, Pippa J; Sayer, Martin D J; Smale, Dan A

    2018-06-03

    Global climate change is affecting carbon cycling by driving changes in primary productivity and rates of carbon fixation, release and storage within Earth's vegetated systems. There is, however, limited understanding of how carbon flow between donor and recipient habitats will respond to climatic changes. Macroalgal-dominated habitats, such as kelp forests, are gaining recognition as important carbon donors within coastal carbon cycles, yet rates of carbon assimilation and transfer through these habitats are poorly resolved. Here, we investigated the likely impacts of ocean warming on coastal carbon cycling by quantifying rates of carbon assimilation and transfer in Laminaria hyperborea kelp forests-one of the most extensive coastal vegetated habitat types in the NE Atlantic-along a latitudinal temperature gradient. Kelp forests within warm climatic regimes assimilated, on average, more than three times less carbon and donated less than half the amount of particulate carbon compared to those from cold regimes. These patterns were not related to variability in other environmental parameters. Across their wider geographical distribution, plants exhibited reduced sizes toward their warm-water equatorward range edge, further suggesting that carbon flow is reduced under warmer climates. Overall, we estimated that Laminaria hyperborea forests stored ~11.49 Tg C in living biomass and released particulate carbon at a rate of ~5.71 Tg C year -1 . This estimated flow of carbon was markedly higher than reported values for most other marine and terrestrial vegetated habitat types in Europe. Together, our observations suggest that continued warming will diminish the amount of carbon that is assimilated and transported through temperate kelp forests in NE Atlantic, with potential consequences for the coastal carbon cycle. Our findings underline the need to consider climate-driven changes in the capacity of ecosystems to fix and donate carbon when assessing the impacts of climate change on carbon cycling. © 2018 The Authors Global Change Biology Published by John Wiley & Sons Ltd.

  13. Salivary gland transfer to prevent radiation-induced xerostomia: a systematic review and meta-analysis.

    PubMed

    Sood, Amit J; Fox, Nyssa F; O'Connell, Brendan P; Lovelace, Tiffany L; Nguyen, Shaun A; Sharma, Anand K; Hornig, Joshua D; Day, Terry A

    2014-02-01

    Salivary gland transfer (SGT) has the potential to prevent radiation-induced xerostomia. We attempt to analyze the efficacy of SGT in prevention of xerostomia and maintenance of salivary flow rates after radiation treatment (XRT). Systematic review and meta-analysis. Primary endpoint was efficacy of SGT in prevention of radiation-induced xerostomia. Secondary endpoint was change from baseline of unstimulated and stimulated salivary flow rates after XRT. Seven articles, accruing data from 12 institutions, met inclusion criteria. In a total of 177 patients at mean follow-up of 22.7months, SGT prevented radiation-induced xerostomia in 82.7% (95% CI, 76.6-87.7%) of patients. Twelve months after XRT, unstimulated and stimulated salivary flow rates rose to 88% and 76% of baseline values, respectively. In comparison to control subjects twelve months after XRT, SGT subjects' unstimulated (75% vs. 11%) and stimulated (86% vs. 8%) salivary flow rates were drastically higher in SGT patients. Salivary gland transfer appears to be highly effective in preventing the incidence of xerostomia in patients receiving definitive head and neck radiation therapy. Copyright © 2013 Elsevier Ltd. All rights reserved.

  14. The use of laminar tube flow in the study of hydrodynamic and chemical influences on polymer flocculation of Escherichia coli.

    PubMed

    Whittington, P N; George, N

    1992-08-05

    The optimization of microbial flocculation for subsequent biomass separation must relate the floc properties to separation process criteria. The effects of flocculant type, dose, and hydrodynamic conditions on floc formation in laminar tube flow were determined for an Escherichia coli system. Combined with an on-line aggregation sensor, this technique allows the flocculation process to be rapidly optimized. This is important, because interbatch variation in fermentation broth has consequences for flocculation control and subsequent downstream processing. Changing tube diameter and length while maintaining a constant flow rate allowed independent study of the effects of shear and time on the flocculation rate and floc characteristics. Tube flow at higher shear rates increased the rate and completeness of flocculation, but reduced the maximum floc size attained. The mechanism for this size limitation does not appear to be fracture or erosion of existing flocs. Rearrangement of particles within the flocs appears to be most likely. The Camp number predicted the extent of flocculation obtained in terms of the reduction in primary particle number, but not in terms of floc size.

  15. Depicting mass flow rate of R134a /LPG refrigerant through straight and helical coiled adiabatic capillary tubes of vapor compression refrigeration system using artificial neural network approach

    NASA Astrophysics Data System (ADS)

    Gill, Jatinder; Singh, Jagdev

    2018-07-01

    In this work, an experimental investigation is carried out with R134a and LPG refrigerant mixture for depicting mass flow rate through straight and helical coil adiabatic capillary tubes in a vapor compression refrigeration system. Various experiments were conducted under steady-state conditions, by changing capillary tube length, inner diameter, coil diameter and degree of subcooling. The results showed that mass flow rate through helical coil capillary tube was found lower than straight capillary tube by about 5-16%. Dimensionless correlation and Artificial Neural Network (ANN) models were developed to predict mass flow rate. It was found that dimensionless correlation and ANN model predictions agreed well with experimental results and brought out an absolute fraction of variance of 0.961 and 0.988, root mean square error of 0.489 and 0.275 and mean absolute percentage error of 4.75% and 2.31% respectively. The results suggested that ANN model shows better statistical prediction than dimensionless correlation model.

  16. Reaction processes and permeability changes during CO2-rich brine flow through fractured Portland cement

    NASA Astrophysics Data System (ADS)

    Abdoulghafour, H.; Luquot, L.; Gouze, P.

    2012-12-01

    So far, cement alteration was principally studied experimentally using batch reactor (with static or renewed fluid). All exhibit similar carbonation mechanisms. The acidic solution, formed by the dissolution of the CO2 into the pore water or directly surrounding the cement sample, diffuses into the cement and induces dissolution reactions of the cement hydrates in particular portlandite and CSH. The calcium released by the dissolution of these calcium bearing phases combining with carbonate ions of the fluid forms calcium carbonates. The cement pH, initially around 13, falls to values where carbonate ion is the most dominant element (pH ~ 9), then CaCO3 phases can precipitate. These studies mainly associate carbonation process with a reduction of porosity and permeability. Indeed an increase of volume (about 10%) is expected during the formation of calcite from portlandite (equation 2) assuming a stoichiometric reaction. Here we investigated the cement alteration mechanisms in the frame of a controlled continuous renewal of CO2-rich fluid in a fracture. This situation is that expected when seepage is activated by the mechanical failure of the cement material that initially seals two layers of distinctly different pressure: the storage reservoir and the aquifer above the caprock, for instance. We study the effect of flow rates from quasi-static flow to higher flow rates for well-connected fractures. In the quasi-static case we observed an extensive conversion of portlandite (Ca(OH)2) to calcite in the vicinity of the fracture similar to that observed in the published batch experiments. Eventually, the fracture was almost totally healed. The experiments with constant flow revealed a different behaviour triggered by the continuous renewing of the reactants and withdrawal of reaction products. We showed that calcite precipitation is more efficient for low flow rate. With intermediate flow rate, we measured that permeability increases slowly at the beginning of the experiment and then remains constant due to calcite precipitation in replacement of CSH and CH into fracture border. With higher flow rate, we measured a constant permeability which can be explained by the development of a highly hydrated Si-rich zone which maintains the initial fracture aperture during all over the experiment while noticeable mass is released from the sample. These preliminary results emphasize that more complex behaviours than that envisaged from batch experiments may take place in the vicinity of flowing fractures. We demonstrated that if only micro-cracks appear in the cement well, carbonation reaction may heal these micro-cracks and mitigate leakage whereas conductive fractures allowing high flow may represent a risk of perennial leakage because the net carbonation process, including the calcite precipitation and its subsequent re-dissolution, is sufficiently to heal the fracture. However, the precipitation of Si-rich amorphous phases may maintain the initial fracture aperture and limit the leakage rate. Keywords: leakage, cement alteration, flow rate, fracture, permeability changes, reaction processes.

  17. Combined effects of flow condition and parasitism on shoaling behaviour of female guppies Poecilia reticulata.

    PubMed

    Hockley, F A; Wilson, C A M E; Graham, N; Cable, J

    2014-01-01

    Group living in fish can provide benefits of protection from predators and some parasites, more efficient foraging for food, increased mating opportunities and enhanced energetic benefit when swimming. For riverine species, shoaling behaviour can be influenced by various environmental stressors, yet little is known how flow rate might influence the shoaling of diseased fish shoals. In view of the increasingly unpredictable flow rates in streams and rivers, this study aimed to assess the combined effect of flow condition and parasitism on the shoaling behaviour of a model fish species. Shoal size, shoal cohesion and time spent shoaling of female guppies Poecilia reticulata were compared when infected with the directly transmitted ectoparasite Gyrodactylus turnbulli under flow and static conditions. Flow condition was an important factor in influencing shoaling behaviour of guppies with the fish forming larger shoals in the absence of flow. When a shoal member was infected with G. turnbulli , shoal cohesion was reduced, but the magnitude of this effect was dependent on flow condition. In both flow and static conditions, bigger fish formed larger shoals than smaller counterparts. Future changes to stream hydrology with more frequent flooding and drought events will affect the shoaling tendency of fish. During high-flow events, diseased fish may not be able to keep up with shoal mates and therefore have a higher risk of predation. Additionally, these findings may be important for aquaria and farmed species where an increase in flow rate may reduce aggregation in fish.

  18. Constitutive Modeling of the High-Temperature Flow Behavior of α-Ti Alloy Tube

    NASA Astrophysics Data System (ADS)

    Lin, Yanli; Zhang, Kun; He, Zhubin; Fan, Xiaobo; Yan, Yongda; Yuan, Shijian

    2018-04-01

    In the hot metal gas forming process, the deformation conditions, such as temperature, strain rate and deformation degree, are often prominently changed. The understanding of the flow behavior of α-Ti seamless tubes over a relatively wide range of temperatures and strain rates is important. In this study, the stress-strain curves in the temperature range of 973-1123 K and the initial strain rate range of 0.0004-0.4 s-1 were measured by isothermal tensile tests to conduct a constitutive analysis and a deformation behavior analysis. The results show that the flow stress decreases with the decrease in the strain rate and the increase of the deformation temperature. The Fields-Backofen model and Fields-Backofen-Zhang model were used to describe the stress-strain curves. The Fields-Backofen-Zhang model shows better predictability on the flow stress than the Fields-Backofen model, but there exists a large deviation in the deformation condition of 0.4 s-1. A modified Fields-Backofen-Zhang model is proposed, in which a strain rate term is introduced. This modified Fields-Backofen-Zhang model gives a more accurate description of the flow stress variation under hot forming conditions with a higher strain rate up to 0.4 s-1. Accordingly, it is reasonable to adopt the modified Fields-Backofen-Zhang model for the hot forming process which is likely to reach a higher strain rate, such as 0.4 s-1.

  19. Constitutive Modeling of the High-Temperature Flow Behavior of α-Ti Alloy Tube

    NASA Astrophysics Data System (ADS)

    Lin, Yanli; Zhang, Kun; He, Zhubin; Fan, Xiaobo; Yan, Yongda; Yuan, Shijian

    2018-05-01

    In the hot metal gas forming process, the deformation conditions, such as temperature, strain rate and deformation degree, are often prominently changed. The understanding of the flow behavior of α-Ti seamless tubes over a relatively wide range of temperatures and strain rates is important. In this study, the stress-strain curves in the temperature range of 973-1123 K and the initial strain rate range of 0.0004-0.4 s-1 were measured by isothermal tensile tests to conduct a constitutive analysis and a deformation behavior analysis. The results show that the flow stress decreases with the decrease in the strain rate and the increase of the deformation temperature. The Fields-Backofen model and Fields-Backofen-Zhang model were used to describe the stress-strain curves. The Fields-Backofen-Zhang model shows better predictability on the flow stress than the Fields-Backofen model, but there exists a large deviation in the deformation condition of 0.4 s-1. A modified Fields-Backofen-Zhang model is proposed, in which a strain rate term is introduced. This modified Fields-Backofen-Zhang model gives a more accurate description of the flow stress variation under hot forming conditions with a higher strain rate up to 0.4 s-1. Accordingly, it is reasonable to adopt the modified Fields-Backofen-Zhang model for the hot forming process which is likely to reach a higher strain rate, such as 0.4 s-1.

  20. Projected effects of Climate-change-induced flow alterations on stream macroinvertebrate abundances.

    PubMed

    Kakouei, Karan; Kiesel, Jens; Domisch, Sami; Irving, Katie S; Jähnig, Sonja C; Kail, Jochem

    2018-03-01

    Global change has the potential to affect river flow conditions which are fundamental determinants of physical habitats. Predictions of the effects of flow alterations on aquatic biota have mostly been assessed based on species ecological traits (e.g., current preferences), which are difficult to link to quantitative discharge data. Alternatively, we used empirically derived predictive relationships for species' response to flow to assess the effect of flow alterations due to climate change in two contrasting central European river catchments. Predictive relationships were set up for 294 individual species based on (1) abundance data from 223 sampling sites in the Kinzig lower-mountainous catchment and 67 sites in the Treene lowland catchment, and (2) flow conditions at these sites described by five flow metrics quantifying the duration, frequency, magnitude, timing and rate of flow events using present-day gauging data. Species' abundances were predicted for three periods: (1) baseline (1998-2017), (2) horizon 2050 (2046-2065) and (3) horizon 2090 (2080-2099) based on these empirical relationships and using high-resolution modeled discharge data for the present and future climate conditions. We compared the differences in predicted abundances among periods for individual species at each site, where the percent change served as a proxy to assess the potential species responses to flow alterations. Climate change was predicted to most strongly affect the low-flow conditions, leading to decreased abundances of species up to -42%. Finally combining the response of all species over all metrics indicated increasing overall species assemblage responses in 98% of the studied river reaches in both projected horizons and were significantly larger in the lower-mountainous Kinzig compared to the lowland Treene catchment. Such quantitative analyses of freshwater taxa responses to flow alterations provide valuable tools for predicting potential climate-change impacts on species abundances and can be applied to any stressor, species, or region.

  1. Mathematical modeling of filling of gas centrifuge cascade for nickel isotope separation by various feed flow rate

    NASA Astrophysics Data System (ADS)

    Ushakov, Anton; Orlov, Alexey; Sovach, Victor P.

    2018-03-01

    This article presents the results of research filling of gas centrifuge cascade for separation of the multicomponent isotope mixture with process gas by various feed flow rate. It has been used mathematical model of the nonstationary hydraulic and separation processes occurring in the gas centrifuge cascade. The research object is definition of the regularity transient of nickel isotopes into cascade during filling of the cascade. It is shown that isotope concentrations into cascade stages after its filling depend on variable parameters and are not equal to its concentration on initial isotope mixture (or feed flow of cascade). This assumption is used earlier any researchers for modeling such nonstationary process as set of steady-state concentration of isotopes into cascade. Article shows physical laws of isotope distribution into cascade stage after its filling. It's shown that varying each parameters of cascade (feed flow rate, feed stage number or cascade stage number) it is possible to change isotope concentration on output cascade flows (light or heavy fraction) for reduction of duration of further process to set of steady-state concentration of isotopes into cascade.

  2. Near-wall modelling of compressible turbulent flows

    NASA Technical Reports Server (NTRS)

    So, Ronald M. C.

    1990-01-01

    Work was carried out to extend the near-wall models formulated for the incompressible Reynolds stress equations to compressible flows. The idea of splitting the compressible dissipation function into a solenoidal part that is not sensitive to changes of compressibility indicators and a compressible part that is directly affected by these changes is adopted. This means that all models involving the dissipation rate could be expressed in terms of the solenoidal dissipation rate and an equation governing its transport could be formulated to close the set of compressible Reynolds stress equations. The near-wall modelling of the dissipation rate equation is investigated and its behavior near a wall is studied in detail using k-epsilon closure. It is found that all existing modelled equations give the wrong behavior for the dissipation rate near a wall. Improvements are suggested and the resultant behavior is found to be in good agreement with near-wall data. Furthermore, the present modified k-epsilon closure is used too calculate a flat plate boundary layer and the results are compared with four existing k-epsilon closures. These comparisons show that all closures tested give essentially the same flow properties, except in a region very close to the wall. In this region, the present k-epsilon closure calculations are in better agreement with measurements and direct simulation data; in particular, the behavior of the dissipation rate.

  3. Hydrothermal fluid flow and deformation in large calderas: Inferences from numerical simulations

    USGS Publications Warehouse

    Hurwitz, S.; Christiansen, L.B.; Hsieh, P.A.

    2007-01-01

    Inflation and deflation of large calderas is traditionally interpreted as being induced by volume change of a discrete source embedded in an elastic or viscoelastic half-space, though it has also been suggested that hydrothermal fluids may play a role. To test the latter hypothesis, we carry out numerical simulations of hydrothermal fluid flow and poroelastic deformation in calderas by coupling two numerical codes: (1) TOUGH2 [Pruess et al., 1999], which simulates flow in porous or fractured media, and (2) BIOT2 [Hsieh, 1996], which simulates fluid flow and deformation in a linearly elastic porous medium. In the simulations, high-temperature water (350??C) is injected at variable rates into a cylinder (radius 50 km, height 3-5 km). A sensitivity analysis indicates that small differences in the values of permeability and its anisotropy, the depth and rate of hydrothermal injection, and the values of the shear modulus may lead to significant variations in the magnitude, rate, and geometry of ground surface displacement, or uplift. Some of the simulated uplift rates are similar to observed uplift rates in large calderas, suggesting that the injection of aqueous fluids into the shallow crust may explain some of the deformation observed in calderas.

  4. Preliminary report of 48-hours Atosiban administration in spontaneous preterm labor - Doppler blood flow assessment of placental and fetal circulation.

    PubMed

    Grzesiak, Mariusz; Wilczynski, Jan

    2013-01-01

    The aims were to investigate whether there are any changes in placental and fetal circulation during Atosiban tocolysis within the first 48 hours of therapy. Detailed Doppler evaluation of placental and fetal circulation was performed prior to Atosiban administration and thereafter at 24 and 48 hours. Maternal heart rate and the pulsatility index (PI) in both uterine arteries (R-UtA, L-UtA) were assessed. Fetal heart rate (FHR), the resistance (RI) and pulsatility index (PI) of umbilical (UA) and middle cerebral artery (MCA) were measured. Additionally cerebroplacental ratio was calculated. E-wave/A-wave ratio (E/A) for atrioventricular valves, the myocardial performance index (MPI) and shortening fraction (SF) for both ventricles were calculated for both ventricles independently. To determine changes over time in all study variables analysis of variance (ANOVA) for repeated measurements followed by Tukey-Kramer's post hoc test was used. The effects of additional clinical covariates were checked. Maternal heart rate and blood flow in (R-UtA/L-UtA) were not altered significantly during Atosiban administration. No significant changes in FHR as well as Doppler parameters (RI, PI, PSV) in UA and MCA were recorded after 24/48 hours of tocolytic treatment. The mean values of cerebroplacental ratio (CPR) remained unaltered during treatment. Detailed evaluation of fetal cardiac function parameters (E/A, SF, MPI) calculated independently for both ventricles, revealed no significant changes over the time. To our best knowledge this study has been first evaluation of placental and fetal circulation with assessment of cardiac hemodynamic function during 48-hours administration of Atosiban. This kind of tocolysis treatment seems not to alter uterine nor fetal arterial blood flow pattern seriously. Hemodynamic cardiac activity in fetuses has remained unaffected. We cannot conclude definitely that there are absolutely no changes in the fetal hemodynamic condition due to Atosiban. Further studies should be performed to verify its possible influence on fetal venous blood flow.

  5. A fluid response: Alpha-amylase reactions to acute laboratory stress are related to sample timing and saliva flow rate.

    PubMed

    Nagy, Tamás; van Lien, René; Willemsen, Gonneke; Proctor, Gordon; Efting, Marieke; Fülöp, Márta; Bárdos, György; Veerman, Enno C I; Bosch, Jos A

    2015-07-01

    Salivary alpha-amylase (sAA) is used as a sympathetic (SNS) stress marker, though its release is likely co-determined by SNS and parasympathetic (PNS) activation. The SNS and PNS show asynchronous changes during acute stressors, and sAA responses may thus vary with sample timing. Thirty-four participants underwent an eight-minute memory task (MT) and cold pressor task (CPT). Cardiovascular SNS (pre-ejection period, blood pressure) and PNS (heart rate variability) activity were monitored continuously. Unstimulated saliva was collected repeatedly during and after each laboratory stressor, and sAA concentration (U/ml) and secretion (U/minute) determined. Both stressors increased anxiety. The MT caused an immediate and continued cardiac SNS activation, but sAA concentration increased at task cessation only (+54%); i.e., when there was SNS-PNS co-activation. During the MT sAA secretion even decreased (-35%) in conjunction with flow rate and vagal tone. The CPT robustly increased blood pressure but not sAA. In summary, sAA fluctuations did not parallel changes in cardiac SNS activity or anxiety. sAA responses seem contingent on sample timing and flow rate, likely involving both SNS and PNS influences. Verification using other stressors and contexts seems warranted. Copyright © 2015 Elsevier B.V. All rights reserved.

  6. The effect of flow reduction on microphytobenthos development in an alpine river stretch using novel fluorescence techniques

    NASA Astrophysics Data System (ADS)

    Ganglbauer, A.; Bondar-Kunze, E.; Hein, T.; Zeiringer, B.

    2009-04-01

    Many European river systems are affected by flow alterations leading to significant differences of the pristine discharge regime at different temporal scales. Flow regulation measures and water abstraction are changing the extent and frequency of water level changes. In concert with river bed regulation this could affect the hydromorphological situation of river systems and key ecosystem functions. Microphytobenthos is a major component in the physical, chemical and biochemical processes, which occur in river systems and the associated riparian zones. They are significant primary producers in rivers, because of their high turnover rate, rapid colonization along the aquatic-terrestrial boundary, transform nutrients and support via their biomass the food webs in the river and adjacent ecosystems. The developed structure and composition of microphytobenthos is controlled by the hydromorphological conditions and thus, indicates environmental changes. The guiding question for the presented research was to what extent changes in the variability of flow affect microphytobenthos development in a river stretch and to what extent the structure and composition of microphytobenthos changed at the micro scale. To investigate these effects under natural conditions we compared a residual flow section impacted by a hydropower plant with one unaffected section of the River Ybbs, a tributary to the Danube River. The river stretch investigated was a 33 km long stretch between the villages Göstling and Opponitz in Lower Austria. The River Ybbs is draining a catchment of 1,300 km2 and has a mean discharge of 20 m3 s-1.The main benthic algal group are diatoms, which are typical for low order rivers in the Alpine area, characterized by low temperatures throughout the year. We expected that flow velocity explain the extent of microphytobenthos development at the river stretch scale and especially low flow conditions affect the structure and composition of algal biomass at the micro scale. The measurements included field surveys and two experimental settings. During May 2008 we conducted an in-situ experiment with artificial substrata to investigate the effect of flow velocity changes. We exposed glass slides in baskets along two transects in the River Ybbs at two sampling sites and eight different positions. After a period of about four weeks with weekly recurrent measurements including flow velocity, water depth, chlorophyll a content and electron transport rate (ETR) we started our experiment. Glass slides were taken from each position and were exposed in a flow reduced impounded area in the river Ybbs near Göstling. There low flow velocity was used to test the effect on microphytobenthos development. The next ten days daily measurements of flow velocity, water depth, chlorophyll-a content and electron transport rate (ETR) with the pulse amplitude modulated fluorescence method and microscopic analysis were undertaken. Based on these daily measurements under almost stable environmental conditions we could ascertain a shift in the benthic algae community. To assess the distribution along a river stretch we measured 70 sampling points at each sampling side. To characterize the biomass and activity of the microphytobenthos we used Pulse Amplitude Modulated Fluorescence (PAM-Fluorescence). Using this technique allow to measure the biomass (Chlorophyll a) and the ETR (electron transport rate) simultaneously without destroying the structure. With this technique it is possible to The PAM technique measure directly the fluorescence of chlorophyll a in the photosystem two. The quantum yield you get is the probability that a photon can be used photochemically. The quantum yield offers the possibility to illustrate the fitness of algae. Based on these measurements short term responses can be measured and combined with the results of field surveys. These analytical results were used for a habitat modelling approach to describe the microphytobenthos development at 2 scales. First results of the research will be presented.

  7. A stock-flow consistent input-output model with applications to energy price shocks, interest rates, and heat emissions

    NASA Astrophysics Data System (ADS)

    Berg, Matthew; Hartley, Brian; Richters, Oliver

    2015-01-01

    By synthesizing stock-flow consistent models, input-output models, and aspects of ecological macroeconomics, a method is developed to simultaneously model monetary flows through the financial system, flows of produced goods and services through the real economy, and flows of physical materials through the natural environment. This paper highlights the linkages between the physical environment and the economic system by emphasizing the role of the energy industry. A conceptual model is developed in general form with an arbitrary number of sectors, while emphasizing connections with the agent-based, econophysics, and complexity economics literature. First, we use the model to challenge claims that 0% interest rates are a necessary condition for a stationary economy and conduct a stability analysis within the parameter space of interest rates and consumption parameters of an economy in stock-flow equilibrium. Second, we analyze the role of energy price shocks in contributing to recessions, incorporating several propagation and amplification mechanisms. Third, implied heat emissions from energy conversion and the effect of anthropogenic heat flux on climate change are considered in light of a minimal single-layer atmosphere climate model, although the model is only implicitly, not explicitly, linked to the economic model.

  8. Effect of altered arterial perfusion pressure on vascular conductance and muscle blood flow dynamic response during exercise in humans.

    PubMed

    Villar, Rodrigo; Hughson, Richard L

    2013-03-01

    Changes in vascular conductance (VC) are required to counter changes in muscle perfusion pressure (MPP) to maintain muscle blood flow (MBF) during exercise. We investigated the recruitment of VC as a function of peak VC measured in three body positions at two different work rates to test the hypothesis that adaptations in VC compensated changes in MPP at low-power output (LPO), but not at high-power output (HPO). Eleven healthy volunteers exercised at LPO and HPO (repeated plantar flexion contractions at 20-30% maximal voluntary contraction, respectively) in horizontal (HOR), 35° head-down tilt (HDT), and 45° head-up tilt (HUT). Muscle blood flow velocity and popliteal diameter were measured by ultrasound to determine MBF, and VC was estimated by dividing MBF flow by MPP. Peak VC was unaffected by body position. The rates of increase in MBF and VC were significantly faster in HUT and slower in HDT than HOR, and rates were faster in LPO than HPO. During LPO exercise, the increase in, and steady-state values of, MBF were less for HUT and HDT than HOR; the increase in VC was less in HUT than HOR and HDT. During HPO exercise, MBF in the HDT was reduced compared with HOR and HUT, even though VC reached 92% VC peak, which was greater than HOR, which was, in turn, greater than HUT. Reduced MBF during HPO HDT exercise had the functional consequence of a significant increase in muscle electromyographic index, revealing the effects of MPP on O2 delivery during exercise.

  9. Efficacy of Transcutaneous Electric Nerve Stimulation on Parotid Saliva Flow Rate in Relation to Age and Gender

    PubMed Central

    Dhillon, Manu; M Raju, Srinivasa; S Mohan, Raviprakash; Tomar, Divya

    2016-01-01

    Statement of the Problem Treatment with salivary substitutes and stimulation of salivary flow by either mechanical or pharmacologic methods has side effects and only provides symptomatic relief but no long-lasting results. Purpose To assess the effectiveness of extraoral transcutaneous electric nerve stimulation (TENS) as a mean of stimulating salivary function in healthy adult subjects; as well as to determine the gender and age-dependent changes in salivary flow rates of unstimulated and stimulated parotid saliva. Materials and Method Hundred patients were divided into two groups; Group I aged 20-40 and Group II aged ≥ 60 years. The TENS electrode pads were externally placed on the skin overlying the parotid glands. Unstimulated and stimulated parotid saliva was collected for 5 minutes each by using standardized collection techniques. Results Eighty seven of 100 subjects demonstrated increased salivary flow when stimulated via the TENS unit. Ten experienced no increase and 3 experienced a decrease. The mean unstimulated salivary flow rate was 0.01872 ml/min in Group I and 0.0088 ml/min in Group II. The mean stimulated salivary flow rate was 0.03084 ml/min (SD= 0.01248) in Group I, and 0.01556 ml/min (SD 0.0101) in Group II. After stimulation, the amount of salivary flow increased significantly in both groups (p< 0.001). Statistical comparison of the two groups revealed them to be significantly different (p< 0.001), with Group I producing more saliva. Gender-wise, no statistically significant difference was seen among the subjects in Group I (p = 0.148), and those in Group II (p= 0.448). Out of 12 subjects with 0 baseline flows, 7 continued to have no flow. Five subjects observed side effects, although minimal and transient. Conclusion The TENS unit was effective in increasing parotid gland salivary flow in healthy subjects. There was age-related but no gender-related variability in parotid salivary flow rate. PMID:27602390

  10. Efficacy of Transcutaneous Electric Nerve Stimulation on Parotid Saliva Flow Rate in Relation to Age and Gender.

    PubMed

    Dhillon, Manu; M Raju, Srinivasa; S Mohan, Raviprakash; Tomar, Divya

    2016-09-01

    Treatment with salivary substitutes and stimulation of salivary flow by either mechanical or pharmacologic methods has side effects and only provides symptomatic relief but no long-lasting results. To assess the effectiveness of extraoral transcutaneous electric nerve stimulation (TENS) as a mean of stimulating salivary function in healthy adult subjects; as well as to determine the gender and age-dependent changes in salivary flow rates of unstimulated and stimulated parotid saliva. Hundred patients were divided into two groups; Group I aged 20-40 and Group II aged ≥ 60 years. The TENS electrode pads were externally placed on the skin overlying the parotid glands. Unstimulated and stimulated parotid saliva was collected for 5 minutes each by using standardized collection techniques. Eighty seven of 100 subjects demonstrated increased salivary flow when stimulated via the TENS unit. Ten experienced no increase and 3 experienced a decrease. The mean unstimulated salivary flow rate was 0.01872 ml/min in Group I and 0.0088 ml/min in Group II. The mean stimulated salivary flow rate was 0.03084 ml/min (SD= 0.01248) in Group I, and 0.01556 ml/min (SD 0.0101) in Group II. After stimulation, the amount of salivary flow increased significantly in both groups (p< 0.001). Statistical comparison of the two groups revealed them to be significantly different (p< 0.001), with Group I producing more saliva. Gender-wise, no statistically significant difference was seen among the subjects in Group I (p = 0.148), and those in Group II (p= 0.448). Out of 12 subjects with 0 baseline flows, 7 continued to have no flow. Five subjects observed side effects, although minimal and transient. The TENS unit was effective in increasing parotid gland salivary flow in healthy subjects. There was age-related but no gender-related variability in parotid salivary flow rate.

  11. Influences of hydraulic gradient, surface roughness, intersecting angle, and scale effect on nonlinear flow behavior at single fracture intersections

    NASA Astrophysics Data System (ADS)

    Li, Bo; Liu, Richeng; Jiang, Yujing

    2016-07-01

    Fluid flow tests were conducted on two crossed fracture models for which the geometries of fracture segments and intersections were measured by utilizing a visualization technique using a CCD (charged coupled device) camera. Numerical simulations by solving the Navier-Stokes equations were performed to characterize the fluid flow at fracture intersections. The roles of hydraulic gradient, surface roughness, intersecting angle, and scale effect in the nonlinear fluid flow behavior through single fracture intersections were investigated. The simulation results of flow rate agreed well with the experimental results for both models. The experimental and simulation results showed that with the increment of the hydraulic gradient, the ratio of the flow rate to the hydraulic gradient, Q/J, decreases and the relative difference of Q/J between the calculation results employing the Navier-Stokes equations and the cubic law, δ, increases. When taking into account the fracture surface roughness quantified by Z2 ranging 0-0.42 for J = 1, the value of δ would increase by 0-10.3%. The influences of the intersecting angle on the normalized flow rate that represents the ratio of the flow rate in a segment to the total flow rate, Ra, and the ratio of the hydraulic aperture to the mechanical aperture, e/E, are negligible when J < 10-3, whereas their values change significantly when J > 10-2. Based on the regression analysis on simulation results, a mathematical expression was proposed to quantify e/E, involving variables of J and Rr, where Rr is the radius of truncating circles centered at an intersection. For E/Rr > 10-2, e/E varies significantly and the scale of model has large impacts on the nonlinear flow behavior through intersections, while for E/Rr < 10-3, the scale effect is negligibly small. Finally, a necessary condition to apply the cubic law to fluid flow through fracture intersections is suggested as J < 10-3, E/Rr < 10-3, and Z2 = 0.

  12. Flow reversal and thermal limit in a heated rectangular channel

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cheng, L.Y.; Tichler, P.R.; Yang, B.W.

    The thermal limit in a vertical rectangular channel was determined in a series of experiments whereby the internal coolant underwent a change in flow direction from forced downflow to upward natural circulation. The tests were designed to simulate the flow reversal transient in the High Flux Beam Reactor. A number of parameters were varied in the flow reversal experiments to examine their effects on the thermal limit. Among the parameters varied were the rate of flow coastdown, inlet subcooling, water level in the upper plenum, bypass ratio (ratio of initial flow through the heated section to initial flow through themore » bypass orifice), and single- verses double-sided heating.« less

  13. Microtopographic evolution of lava flows at Cima volcanic field, Mojave Desert, California

    NASA Technical Reports Server (NTRS)

    Farr, Tom G.

    1992-01-01

    Microtopographic profiles were measured and power spectra calculated for dated lava flow surfaces at Cima volcanic field in the eastern Mojave Desert of California in order to quantify changes in centimeter- to meter-scale roughness as a function of age. For lava flows younger than about 0.8 m.y., roughness over all spatial scales decreases with age, with meter-scale roughness decreasing slightly more than centimeter scales. Flows older than about 0.8 m.y. show a reversal of this trend, becoming as rough as young flows at these scales. Modeling indicates that eolian deposition can explain most of the change observed in the offset, or roughness amplitude, of power spectra of flow surface profiles up to 0.8 m.y. Other processes, such as rubbing and stone pavement development, appear to have a minor effect in this age range. Changes in power spectra of surfaces older than about 0.8 m.y. are consistent with roughening due to fluvial dissection. These results agree qualitatively with a process-response model that attributes systematic changes in flow surface morphology to cyclic changes in the rates of eolian, soil formation, and fluvial processes. Identification of active surficial processes and estimation of the extent of their effects, or stage of surficial evolution, through measurement of surface roughness will help put the correlation of surficial units on a quantitative basis. This may form the basis for the use of radar remote sensing data to help in regional correlations of surficial units.

  14. Three dimensional investigation of the shock train structure in a convergent-divergent nozzle

    NASA Astrophysics Data System (ADS)

    Mousavi, Seyed Mahmood; Roohi, Ehsan

    2014-12-01

    Three-dimensional computational fluid dynamics analyses have been employed to study the compressible and turbulent flow of the shock train in a convergent-divergent nozzle. The primary goal is to determine the behavior, location, and number of shocks. In this context, full multi-grid initialization, Reynolds stress turbulence model (RSM), and the grid adaption techniques in the Fluent software are utilized under the 3D investigation. The results showed that RSM solution matches with the experimental data suitably. The effects of applying heat generation sources and changing inlet flow total temperature have been investigated. Our simulations showed that changes in the heat generation rate and total temperature of the intake flow influence on the starting point of shock, shock strength, minimum pressure, as well as the maximum flow Mach number.

  15. Equations of motion for the variable mass flow-variable exhaust velocity rocket

    NASA Technical Reports Server (NTRS)

    Tempelman, W. H.

    1972-01-01

    An equation of motion for a one dimensional rocket is derived as a function of the mass flow rate into the acceleration chamber and the velocity distribution along the chamber, thereby including the transient flow changes in the chamber. The derivation of the mass density requires the introduction of the special time coordinate. The equation of motion is derived from both classical force and momentum approaches and is shown to be consistent with the standard equation expressed in terms of flow parameters at the exit to the acceleration chamber.

  16. Methods of measurement signal acquisition from the rotational flow meter for frequency analysis

    NASA Astrophysics Data System (ADS)

    Świsulski, Dariusz; Hanus, Robert; Zych, Marcin; Petryka, Leszek

    One of the simplest and commonly used instruments for measuring the flow of homogeneous substances is the rotational flow meter. The main part of such a device is a rotor (vane or screw) rotating at a speed which is the function of the fluid or gas flow rate. A pulse signal with a frequency proportional to the speed of the rotor is obtained at the sensor output. For measurements in dynamic conditions, a variable interval between pulses prohibits the analysis of the measuring signal. Therefore, the authors of the article developed a method involving the determination of measured values on the basis of the last inter-pulse interval preceding the moment designated by the timing generator. For larger changes of the measured value at a predetermined time, the value can be determined by means of extrapolation of the two adjacent interpulse ranges, assuming a linear change in the flow. The proposed methods allow analysis which requires constant spacing between measurements, allowing for an analysis of the dynamics of changes in the test flow, eg. using a Fourier transform. To present the advantages of these methods simulations of flow measurement were carried out with a DRH-1140 rotor flow meter from the company Kobold.

  17. Viscosity changes of riparian water controls diurnal fluctuations of stream-flow and DOC concentration

    NASA Astrophysics Data System (ADS)

    Schwab, Michael; Klaus, Julian; Pfister, Laurent; Weiler, Markus

    2015-04-01

    Diurnal fluctuations in stream-flow are commonly explained as being triggered by the daily evapotranspiration cycle in the riparian zone, leading to stream flow minima in the afternoon. While this trigger effect must necessarily be constrained by the extent of the growing season of vegetation, we here show evidence of daily stream flow maxima in the afternoon in a small headwater stream during the dormant season. We hypothesize that the afternoon maxima in stream flow are induced by viscosity changes of riparian water that is caused by diurnal temperature variations of the near surface groundwater in the riparian zone. The patterns were observed in the Weierbach headwater catchment in Luxembourg. The catchment is covering an area of 0.45 km2, is entirely covered by forest and is dominated by a schistous substratum. DOC concentration at the outlet of the catchment was measured with the field deployable UV-Vis spectrometer spectro::lyser (scan Messtechnik GmbH) with a high frequency of 15 minutes over several months. Discharge was measured with an ISCO 4120 Flow Logger. During the growing season, stream flow shows a frequently observed diurnal pattern with discharge minima in the afternoon. During the dormant season, a long dry period with daily air temperature amplitudes of around 10 ° C occurred in March and April 2014, with discharge maxima in the afternoon. The daily air temperature amplitude led to diurnal variations in the water temperature of the upper 10 cm of the riparian zone. Higher riparian water temperatures cause a decrease in water viscosity and according to the Hagen-Poiseuille equation, the volumetric flow rate is inversely proportional to viscosity. Based on the Hagen-Poiseuille equation and the viscosity changes of water, we calculated higher flow rates of near surface groundwater through the riparian zone into the stream in the afternoon which explains the stream flow maxima in the afternoon. With the start of the growing season, the viscosity induced diurnal effect is overlain by the stronger influence of evapotranspiration. Diurnal DOC fluctuations show daily maxima in the afternoon. While daily variations in DOC concentrations are often explained by faster in-stream biogeochemical processes during daylight, we here propose that the viscosity effect in the riparian zone could explain the afternoon peaks in DOC concentrations. Our records show that daily water temperature variations and therefore viscosity changes only occur in the near surface parts of the riparian zone, where the DOC concentrations are higher than in deeper parts of the riparian zone. We calculated, that the viscosity induced higher flow rates from the near surface parts of the riparian zone can explain the DOC concentration maxima in the afternoon. As the viscosity effect does not disappear during the growing season but is just smaller than the evapotranspiration effect, the DOC concentration pattern is not changing between the dormant and growing seasons. The different controls of diurnal fluctuations of stream-flow and water quality concentrations need to be carefully considered in order to better understand the different patterns in catchment hydrology.

  18. Uncertainty Management in Urban Water Engineering Adaptation to Climate Change - abstract

    EPA Science Inventory

    Current water resource planning and engineering assume a stationary climate, in which the observed historical water flow rate and water quality variations are often used to define the technical basis. When the non-stationarity is considered, however, climate change projection co...

  19. Characterization of arterial traffic congestion through analysis of operational parameters (gap acceptance and lane changing).

    DOT National Transportation Integrated Search

    2010-05-01

    This project monitored an urban arterial highway to characterize recurring congestion. There were two major initiatives in the project. The first one focused on observed variations in gap acceptance and lane changing in relation to traffic flow rates...

  20. Experimental study of the influence of flow passage subtle variation on mixed-flow pump performance

    NASA Astrophysics Data System (ADS)

    Bing, Hao; Cao, Shuliang

    2014-05-01

    In the mixed-flow pump design, the shape of the flow passage can directly affect the flow capacity and the internal flow, thus influencing hydraulic performance, cavitation performance and operation stability of the mixed-flow pump. However, there is currently a lack of experimental research on the influence mechanism. Therefore, in order to analyze the effects of subtle variations of the flow passage on the mixed-flow pump performance, the frustum cone surface of the end part of inlet contraction flow passage of the mixed-flow pump is processed into a cylindrical surface and a test rig is built to carry out the hydraulic performance experiment. In this experiment, parameters, such as the head, the efficiency, and the shaft power, are measured, and the pressure fluctuation and the noise signal are also collected. The research results suggest that after processing the inlet flow passage, the head of the mixed-flow pump significantly goes down; the best efficiency of the mixed-flow pump drops by approximately 1.5%, the efficiency decreases more significantly under the large flow rate; the shaft power slightly increases under the large flow rate, slightly decreases under the small flow rate. In addition, the pressure fluctuation amplitudes on both the impeller inlet and the diffuser outlet increase significantly with more drastic pressure fluctuations and significantly lower stability of the internal flow of the mixed-flow pump. At the same time, the noise dramatically increases. Overall speaking, the subtle variation of the inlet flow passage leads to a significant change of the mixed-flow pump performance, thus suggesting a special attention to the optimization of flow passage. This paper investigates the influence of the flow passage variation on the mixed-flow pump performance by experiment, which will benefit the optimal design of the flow passage of the mixed-flow pump.

  1. Glacial-interglacial climate changes recorded by debris flow fan deposits, Owens Valley, California

    NASA Astrophysics Data System (ADS)

    D'Arcy, Mitch; Roda-Boluda, Duna C.; Whittaker, Alexander C.

    2017-08-01

    It is hotly debated whether and how climate changes are recorded by terrestrial stratigraphy. Basin sediments produced by catchment-alluvial fan systems may record past climate over a variety of timescales, and could offer unique information about how climate controls sedimentation. Unfortunately, there are fundamental uncertainties about how climatic variables such as rainfall and temperature translate into sedimentological signals. Here, we examine 35 debris flow fan surfaces in Owens Valley, California, that record deposition throughout the past 125,000 years, during which climate has varied significantly. We show that the last full glacial-interglacial cycle is recorded with high fidelity by the grain size distributions of the debris flow deposits. These flows transported finer sediment during the cooler glacial climate, and became systematically coarser-grained as the climate warmed and dried. We explore the physical mechanisms that might explain this signal, and rule out changes in sediment supply through time. Instead, we propose that grain size records past changes in storm intensity, which is responsible for debris flow initiation in this area and is decoupled from average rainfall rates. This is supported by an exponential Clausius-Clapeyron-style scaling between grain size and temperature, and also reconciles with climate dynamics and the initiation of debris flows. The fact that these alluvial fans exhibit a strong, sustained sensitivity to orbital climate changes sheds new light on how eroding landscapes and their sedimentary products respond to climatic forcing. Finally, our findings highlight the importance of threshold-controlled events, such as storms and debris flows, in driving erosion and sedimentation at the Earth's surface in response to climate change.

  2. Lattice Boltzmann Study of Bubbles on a Patterned Superhydrophobic Surface under Shear Flow

    NASA Astrophysics Data System (ADS)

    Chen, Wei; Wang, Kai; Hou, Guoxiang; Leng, Wenjun

    2018-01-01

    This paper studies shear flow over a 2D patterned superhydrophobic surface using lattice Boltzmann method (LBM). Single component Shan-Chen multiphase model and Carnahan-Starling EOS are adopted to handle the liquid-gas flow on superhydrophobic surface with entrapped micro-bubbles. The shape of bubble interface and its influence on slip length under different shear rates are investigated. With increasing shear rate, the bubble interface deforms. Then the contact lines are depinned from the slot edges and move downstream. When the shear rate is high enough, a continuous gas layer forms. If the protrusion angle is small, the gas layer forms and collapse periodically, and accordingly the slip length changes periodically. While if the protrusion angle is large, the gas layer is steady and separates the solid wall from liquid, resulting in a very large slip length.

  3. Time-averaged discharge rate of subaerial lava at Kīlauea Volcano, Hawai‘i, measured from TanDEM-X interferometry: Implications for magma supply and storage during 2011-2013

    USGS Publications Warehouse

    Poland, Michael P.

    2014-01-01

    Differencing digital elevation models (DEMs) derived from TerraSAR add-on for Digital Elevation Measurements (TanDEM-X) synthetic aperture radar imagery provides a measurement of elevation change over time. On the East Rift Zone (EZR) of Kīlauea Volcano, Hawai‘i, the effusion of lava causes changes in topography. When these elevation changes are summed over the area of an active lava flow, it is possible to quantify the volume of lava emplaced at the surface during the time spanned by the TanDEM-X data—a parameter that can be difficult to measure across the entirety of an ~100 km2 lava flow field using ground-based techniques or optical remote sensing data. Based on the differences between multiple TanDEM-X-derived DEMs collected days to weeks apart, the mean dense-rock equivalent time-averaged discharge rate of lava at Kīlauea between mid-2011 and mid-2013 was approximately 2 m3/s, which is about half the long-term average rate over the course of Kīlauea's 1983–present ERZ eruption. This result implies that there was an increase in the proportion of lava stored versus erupted, a decrease in the rate of magma supply to the volcano, or some combination of both during this time period. In addition to constraining the time-averaged discharge rate of lava and the rates of magma supply and storage, topographic change maps derived from space-based TanDEM-X data provide insights into the four-dimensional evolution of Kīlauea's ERZ lava flow field. TanDEM-X data are a valuable complement to other space-, air-, and ground-based observations of eruptive activity at Kīlauea and offer great promise at locations around the world for aiding with monitoring not just volcanic eruptions but any hazardous activity that results in surface change, including landslides, floods, earthquakes, and other natural and anthropogenic processes.

  4. Gaseous Nitrogen Orifice Mass Flow Calculator

    NASA Technical Reports Server (NTRS)

    Ritrivi, Charles

    2013-01-01

    The Gaseous Nitrogen (GN2) Orifice Mass Flow Calculator was used to determine Space Shuttle Orbiter Water Spray Boiler (WSB) GN2 high-pressure tank source depletion rates for various leak scenarios, and the ability of the GN2 consumables to support cooling of Auxiliary Power Unit (APU) lubrication during entry. The data was used to support flight rationale concerning loss of an orbiter APU/hydraulic system and mission work-arounds. The GN2 mass flow-rate calculator standardizes a method for rapid assessment of GN2 mass flow through various orifice sizes for various discharge coefficients, delta pressures, and temperatures. The calculator utilizes a 0.9-lb (0.4 kg) GN2 source regulated to 40 psia (.276 kPa). These parameters correspond to the Space Shuttle WSB GN2 Source and Water Tank Bellows, but can be changed in the spreadsheet to accommodate any system parameters. The calculator can be used to analyze a leak source, leak rate, gas consumables depletion time, and puncture diameter that simulates the measured GN2 system pressure drop.

  5. Flow quality of NAL two-dimensional transonic wind tunnel. Part 1: Mach number distributions, flow angularities and preliminary study of side wall boundary layer suction

    NASA Technical Reports Server (NTRS)

    Sakakibara, Seizo; Takashima, Kazuaki; Miwa, Hitoshi; Oguni, Yasuo; Sato, Mamoru; Kanda, Hiroshi

    1988-01-01

    Experimental data on the flow quality of the National Aerospace Laboratory two-dimensional transonic wind tunnel are presented. Mach number distributions on the test section axis show good uniformity which is characterized by the two sigma (standard deviation) values of 0.0003 to 0.001 for a range of Mach numbers from 0.4 to 1.0. Flow angularities, which were measured by using a wing model with a symmetrical cross section, remained within 0.04 deg for Mach numbers from 0.2 to 0.8. Side wall boundary layer suction was applied through a pair of porous plates. The variation of aerodynamic properties of the model due to the suction mass flow rate change is presented with a brief discussion. Two dimensionality of the flow over the wing span is expected to be improved by applying the appropriate suction rate, which depends on the Mach number, Reynolds number, and lift coefficient.

  6. Quantification of instantaneous flow rate and dynamically changing effective orifice area using a geometry independent three-dimensional digital color Doppler method: An in vitro study mimicking mitral regurgitation.

    PubMed

    Li, Xiaokui; Wanitkun, Suthep; Li, Xiang-Ning; Hashimoto, Ikuo; Mori, Yoshiki; Rusk, Rosemary A; Hicks, Shannon E; Sahn, David J

    2002-10-01

    Our study was intended to test the accuracy of a 3-dimensional (3D) digital color Doppler flow convergence (FC) method for assessing the effective orifice area (EOA) in a new dynamic orifice model mimicking a variety of mitral regurgitation. FC surface area methods for detecting EOA have been reported to be useful for quantifying the severity of valvular regurgitation. With our new 3D digital direct FC method, all raw velocity data are available and variable Nyquist limits can be selected for computation of direct FC surface area for computing instantaneous flow rate and temporal change of EOA. A 7.0-MHz multiplane transesophageal probe from an ultrasound system (ATL HDI 5000) was linked and controlled by a computer workstation to provide 3D images. Three differently shaped latex orifices (zigzag, arc, and straight slit, each with cutting-edge length of 1 cm) were used to mimic the dynamic orifice of mitral regurgitation. 3D FC surface computation was performed on parallel slices through the 3D data set at aliasing velocities (14-48 cm/s) selected to maximize the regularity and minimize lateral dropout of the visualized 3D FC at 5 points per cardiac cycle. Using continuous wave velocity for each, 3D-calculated EOA was compared with EOA determined by using continuous wave Doppler and the flow rate from a reference ultrasonic flow meter. Simultaneous digital video images were also recorded to define the actual orifice size for 9 stroke volumes (15-55 mL/beat with maximum flow rates 45-182 mL/s). Over the 9 pulsatile flow states and 3 orifices, 3D FC EOAs (0.05-0.63 cm(2)) from different phases of the cardiac cycle in each pump setting correlated well with reference EOA (r = 0.89-0.92, SEE = 0.027-0.055cm(2)) and they also correlated well with digital video images of the actual orifice peak (r = 0.97-0.98, SEE = 0.016-0.019 cm(2)), although they were consistently smaller, as expected by the contraction coefficient. The digital 3D FC method can accurately predict flow rate, and, thus, EOA (in conjunction with continuous wave Doppler), because it allows direct FC surface measurement despite temporal variability of FC shape.

  7. Amplification, attenuation, and dispersion of sound in inhomogeneous flows

    NASA Technical Reports Server (NTRS)

    Kentzer, C. P.

    1975-01-01

    First order effects of gradients in nonuniform potential flows of a compressible gas are included in a dispersion relation for sound waves. Three nondimensional numbers, the ratio of the change in the kinetic energy in one wavelength to the thermal energy of the gas, the ratio of the change in the total energy in one wavelength to the thermal energy, and the ratio of the dillatation frequency (the rate of expansion per unit volume) to the acoustic frequency, play a role in the separation of the effects of flow gradients into isotropic and anisotropic effects. Dispersion and attenuation (or amplification) of sound are found to be proportional to the wavelength for small wavelength, and depend on the direction of wave propagation relative to flow gradients. Modification of ray acoustics for the effects of flow gradients is suggested, and conditions for amplification and attenuation of sound are discussed.

  8. Flow rate of some pharmaceutical diluents through die-orifices relevant to mini-tableting.

    PubMed

    Kachrimanis, K; Petrides, M; Malamataris, S

    2005-10-13

    The effects of cylindrical orifice length and diameter on the flow rate of three commonly used pharmaceutical direct compression diluents (lactose, dibasic calcium phosphate dihydrate and pregelatinised starch) were investigated, besides the powder particle characteristics (particle size, aspect ratio, roundness and convexity) and the packing properties (true, bulk and tapped density). Flow rate was determined for three different sieve fractions through a series of miniature tableting dies of different orifice diameter (0.4, 0.3 and 0.2 cm) and thickness (1.5, 1.0 and 0.5 cm). It was found that flow rate decreased with the increase of the orifice length for the small diameter (0.2 cm) but for the large diameter (0.4 cm) was increased with the orifice length (die thickness). Flow rate changes with the orifice length are attributed to the flow regime (transitional arch formation) and possible alterations in the position of the free flowing zone caused by pressure gradients arising from the flow of self-entrained air, both above the entrance in the die orifice and across it. Modelling by the conventional Jones-Pilpel non-linear equation and by two machine learning algorithms (lazy learning, LL, and feed-forward back-propagation, FBP) was applied and predictive performance of the fitted models was compared. It was found that both FBP and LL algorithms have significantly higher predictive performance than the Jones-Pilpel non-linear equation, because they account both dimensions of the cylindrical die opening (diameter and length). The automatic relevance determination for FBP revealed that orifice length is the third most influential variable after the orifice diameter and particle size, followed by the bulk density, the difference between bulk and tapped densities and the particle convexity.

  9. Implications of surfactant-induced flow for miscible-displacement estimation of air-water interfacial areas in unsaturated porous media.

    PubMed

    Costanza-Robinson, Molly S; Zheng, Zheng; Henry, Eric J; Estabrook, Benjamin D; Littlefield, Malcolm H

    2012-10-16

    Surfactant miscible-displacement experiments represent a conventional means of estimating air-water interfacial area (A(I)) in unsaturated porous media. However, changes in surface tension during the experiment can potentially induce unsaturated flow, thereby altering interfacial areas and violating several fundamental method assumptions, including that of steady-state flow. In this work, the magnitude of surfactant-induced flow was quantified by monitoring moisture content and perturbations to effluent flow rate during miscible-displacement experiments conducted using a range of surfactant concentrations. For systems initially at 83% moisture saturation (S(W)), decreases of 18-43% S(W) occurred following surfactant introduction, with the magnitude and rate of drainage inversely related to the surface tension of the surfactant solution. Drainage induced by 0.1 mM sodium dodecyl benzene sulfonate, commonly used for A(I) estimation, resulted in effluent flow rate increases of up to 27% above steady-state conditions and is estimated to more than double the interfacial area over the course of the experiment. Depending on the surfactant concentration and the moisture content used to describe the system, A(I) estimates varied more than 3-fold. The magnitude of surfactant-induced flow is considerably larger than previously recognized and casts doubt on the reliability of A(I) estimation by surfactant miscible-displacement.

  10. Tearing Instability of a Current Sheet Forming by Sheared Incompressible Flow

    NASA Astrophysics Data System (ADS)

    Tolman, Elizabeth; Loureiro, Nuno; Uzdensky, Dmitri

    2017-10-01

    Sweet-Parker current sheets are unstable to the tearing mode, suggesting they will not form in physical systems. Understanding magnetic reconnection thus requires study of the stability of a current sheet as it forms. Such formation can occur as a result of sheared, sub-Alfvénic incompressible flows into and along the sheet. This work presents an analysis of how tearing perturbations behave in a current sheet forming under the influence of such flows, beginning with a phase when the growth rate of the tearing mode is small and the behavior of perturbations is primarily governed by ideal MHD. Later, after the tearing growth rate becomes significant relative to the time scale of the driving flows, the flows cause a slight reduction in the tearing growth rate and wave vector of the dominant mode. Once the tearing mode enters the nonlinear regime, the flows accelerate the tearing growth slightly; during X-point collapse, the flows have negligible effect on the system behavior. This analysis allows greater understanding of reconnection in evolving systems and increases confidence in the application of tools developed in time-independent current sheets to changing current sheets. This material is based upon work supported by the National Science Foundation Graduate Research Fellowship.

  11. Behavior of CO2/water flow in porous media for CO2 geological storage.

    PubMed

    Jiang, Lanlan; Yu, Minghao; Liu, Yu; Yang, Mingjun; Zhang, Yi; Xue, Ziqiu; Suekane, Tetsuya; Song, Yongchen

    2017-04-01

    A clear understanding of two-phase fluid flow properties in porous media is of importance to CO 2 geological storage. The study visually measured the immiscible and miscible displacement of water by CO 2 using MRI (magnetic resonance imaging), and investigated the factor influencing the displacement process in porous media which were filled with quartz glass beads. For immiscible displacement at slow flow rates, the MR signal intensity of images increased because of CO 2 dissolution; before the dissolution phenomenon became inconspicuous at flow rate of 0.8mLmin -1 . For miscible displacement, the MR signal intensity decreased gradually independent of flow rates, because supercritical CO 2 and water became miscible in the beginning of CO 2 injection. CO 2 channeling or fingering phenomena were more obviously observed with lower permeable porous media. Capillary force decreases with increasing particle size, which would increase permeability and allow CO 2 and water to invade into small pore spaces more easily. The study also showed CO 2 flow patterns were dominated by dimensionless capillary number, changing from capillary finger to stable flow. The relative permeability curve was calculated using Brooks-Corey model, while the results showed the relative permeability of CO 2 slightly decreases with the increase of capillary number. Copyright © 2016 Elsevier Inc. All rights reserved.

  12. Determining of the Parking Manoeuvre and the Taxi Blockage Adjustment Factor for the Saturation Flow Rate at the Outlet Legs of Signalized Intersections: Case Study from Rasht City (Iran)

    NASA Astrophysics Data System (ADS)

    Behbahani, Hamid; Jahangir Samet, Mehdi; Najafi Moghaddam Gilani, Vahid; Amini, Amir

    2017-10-01

    The presence of taxi stops within the area of signalized intersections at the outlet legs due to unnatural behaviour of the taxis, sudden change of lanes, parking manoeuvres activities and stopping the vehicle to discharge or pick up the passengers have led to reduction of saturation flow rate at the outlet leg of signalized intersections and increased delay as well as affecting the performance of a crossing lane. So far, in term of evaluating effective adjustment factors on saturation flow rate at the inlet legs of the signalized intersections, various studies have been carried out, however; there has not been any studies on effective adjustment factors on saturation flow rate at the inlet legs. Hence, the evaluating of the traffic effects of unique behaviours on the saturation flow rate of the outlet leg is very important. In this research the parking manoeuvre time and taxi blockage time were evaluated and analyzed based on the available lane width as well as determining the effective adjustment factors on the saturation flow rate using recording related data at four signalized intersections in Rasht city. The results show that the average parking manoeuvre time is a function of the lane width and is increased as the lane width is reduced. Also, it is suggested to use the values of 7.37 and 11.31 seconds, respectively for the average parking manoeuvre time and the average blockage time of taxies at the outlet legs of signalized intersections for the traffic designing in Rasht city.

  13. Barotrauma and microvascular injury in lungs of nonadult rabbits: effect of ventilation pattern.

    PubMed

    Peevy, K J; Hernandez, L A; Moise, A A; Parker, J C

    1990-06-01

    To study the pulmonary microvascular injury produced by ventilation barotrauma, the isolated perfused lungs of 4 to 6-wk-old New Zealand white rabbits were ventilated by one of the following methods: peak inspiratory pressure (PIP) 23 cm H2O, gas flow rate 1.1 L/min (group 1); PIP 27 cm H2O, gas flow rate 6.9 L/min (group 2); PIP 50 cm H2O, gas flow rate 1.9 L/min (group 3); or PIP 53 cm H2O, gas flow rate 8.3 L/min (group 4). Microvascular permeability was assessed using the capillary filtration coefficient (Kfc) before and 5, 30, and 60 min after a 15-min period of ventilation. Baseline Kfc was not significantly different between groups. A significant increase over the baseline Kfc was noted at 60 min in group 2 and in all postventilation Kfc values in groups 3 and 4 (p less than .05). Group 1 Kfc values did not change significantly after ventilation. At all post-ventilation times, values for Kfc were significantly greater in groups 3 and 4 than in group 1 (p less than .05). Group 4 Kfc values were significantly greater than those in group 2 at 5 and 30 min postventilation. These data indicate that high PIP, and to a lesser extent, high gas flow rates cause microvascular injury in the compliant nonadult lung and suggest that the combination of high PIP and high gas flow rates are the most threatening to microvascular integrity.

  14. Implant Fixture Heat Transfer During Abutment Preparation.

    PubMed

    Aleisa, Khalil; Alkeraidis, Abdullah; Al-Dwairi, Ziad Nawaf; Altahawi, Hamdi; Lynch, Edward

    2015-06-01

    The purpose of the study was to evaluate the effect of water flow rate on the heat transmission in implants during abutment preparation using a diamond bur in a high-speed dental turbine. Titanium-alloy abutments (n = 32) were connected to a titanium-alloy implant embedded in an acrylic resin within a water bath at a controlled temperature of 37°C. The specimens were equally distributed into 2 groups (16 each) according to the water flow rate used during the preparation phase. Group 1 had a water flow rate of 24 mL/min, and group 2 had a water flow rate of 40 mL/min. Each abutment was prepared in the axial plane for 1 minute and in the occlusal plane for 1 minute with a coarse tapered diamond bur using a high-speed dental handpiece. Thermocouples embedded at the cervix of the implant surface were used to record the temperature of heat transmission from the abutment preparation. Heat generation was measured at 3 distinct times (immediately and 30 seconds and 60 seconds after the end of preparation). Statistical analyses were carried out using 2-way analysis of variance and the Student t test. Water flow rates (24 mL vs 40 mL) and time interval had no statistically significant effect on the implant's temperature change during the abutment preparation stage (P = .431 and P = .064, respectively). Increasing the water flow rate from 24 to 40 mL/min had no influence on the temperature of the implant fixture recorded during preparation of the abutment.

  15. Linearized unsteady jet analysis

    NASA Technical Reports Server (NTRS)

    Viets, H.; Piatt, M.

    1979-01-01

    The introduction of a time dependency into a jet flow to change the rate at which it mixes with a coflowing stream or ambient condition is investigated. The advantages and disadvantages of the unsteady flow are discussed in terms of steady state mass and momentum transfer. A linear system which is not limited by frequency constraints and evolves through a simplification of the equations of motion is presented for the analysis of the unsteady flow field generated by the time dependent jet.

  16. A method of calibrating wind velocity sensors with a modified gas flow calibrator

    NASA Technical Reports Server (NTRS)

    Stump, H. P.

    1978-01-01

    A procedure was described for calibrating air velocity sensors in the exhaust flow of a gas flow calibrator. The average velocity in the test section located at the calibrator exhaust was verified from the mass flow rate accurately measured by the calibrator's precision sonic nozzles. Air at elevated pressures flowed through a series of screens, diameter changes, and flow straighteners, resulting in a smooth flow through the open test section. The modified system generated air velocities of 2 to 90 meters per second with an uncertainty of about two percent for speeds below 15 meters per second and four percent for the higher speeds. Wind tunnel data correlated well with that taken in the flow calibrator.

  17. Measurement of OH, O, and NO densities and their correlations with mouse melanoma cell death rate treated by a nanosecond pulsed streamer discharge

    NASA Astrophysics Data System (ADS)

    Yagi, Ippei; Shirakawa, Yuki; Hirakata, Kenta; Akiyama, Taketoshi; Yonemori, Seiya; Mizuno, Kazue; Ono, Ryo; Oda, Tetsuji

    2015-10-01

    Mouse melanoma cells in a culture medium are treated using a nanosecond pulsed streamer discharge plasma and the correlations between the rate of cell death and the densities of reactive species (OH, O, and NO) in the plasma are measured. The plasma is irradiated onto the culture medium surface with a vertical gas flow of an O2/N2 mixture from a glass tube at various gas flow rates and O2 concentrations. The densities of the reactive species are measured very close to the culture medium surface, where the reactive species interact with the culture medium, using laser-induced fluorescence. In the case of the N2 discharge (O2 = 0%), an increase in gas flow rate decreases OH density because it lowers the water vapor concentration by diluting the vapor, which is required for OH production. The increase in gas flow rate also leads to a decreased cell death rate. In the case of the O2/N2 discharge, on the other hand, an increase in O2 concentration at a fixed flow rate does not affect the rate of cell death, although it considerably changes the O and NO densities. These findings indicate that some reactive species derived from water vapor such as OH are responsible for the melanoma cell death, whereas those from O2, such as O and NO, are less likely responsible. They also indicate the importance of water evaporation from the culture medium surface in cell treatment.

  18. Differences in Landsat TM derived lava flow thermal structures during summit and flank eruption at Mount Etna

    NASA Astrophysics Data System (ADS)

    Lombardo, V.; Buongiorno, M. F.; Pieri, D.; Merucci, L.

    2004-06-01

    The simultaneous solution of the Planck equation (the so-called "dual-band" technique) for two shortwave infrared Landsat Thematic Mapper (TM) bands allows an estimate of the fractional area of the hottest part of an active flow and the temperature of the cooler crust. Here, the dual-band method has been applied to a time series of Mount Etna eruptions. The frequency distribution of the fractional area of the hottest component reveals specific differences between summit and flank lava flows. The shape of the density function shows a trend consistent with a Gaussian distribution and suggests a relationship between the moments of the distribution and the emplacement environment. Because flow composition of Etnean lavas generally remains constant during the duration of their emplacement, it appears that the shape of any particular frequency distribution is probably related to fluid mechanical aspects of flow emplacement that affect flow velocity and flow heat loss and thus the rate of formation of the surface crust. These factors include the influence of topographical features such as changes in slope gradient, changes in volume effusion rate, and progressive downflow increases in bulk or effective viscosity. A form of the general theoretical solution for the 'dual-band' system, which illustrates the relationship between radiance in TM bands 5 and 7, corresponding to hot fractional area and crust temperature, is presented. Generally speaking, it appears that for a given flow at any point in time, larger fractional areas of exposed hot material are correlated with higher temperatures and that, while the overall shape of that distribution is common for the flows studied, its amplitude and slope reflect individual flow rheological regimes.

  19. Flow-field characteristics of high-temperature annular buoyant jets and their development laws influenced by ventilation system.

    PubMed

    Wang, Yi; Huang, Yanqiu; Liu, Jiaping; Wang, Hai; Liu, Qiuhan

    2013-01-01

    The flow-field characteristics of high-temperature annular buoyant jets as well as the development laws influenced by ventilation system were studied using numerical methods to eliminate the pollutants effectively in this paper. The development laws of high-temperature annular buoyant jets were analyzed and compared with previous studies, including radial velocity distribution, axial velocity and temperature decay, reattachment position, cross-section diameter, volumetric flow rate, and velocity field characteristics with different pressures at the exhaust hood inlet. The results showed that when the ratio of outer diameter to inner diameter of the annulus was smaller than 5/2, the flow-field characteristics had significant difference compared to circular buoyant jets with the same outer diameter. For similar diameter ratios, reattachment in this paper occurred further downstream in contrast to previous study. Besides, the development laws of volumetric flow rate and cross-section diameter were given with different initial parameters. In addition, through analyzing air distribution characteristics under the coupling effect of high-temperature annular buoyant jets and ventilation system, it could be found that the position where maximum axial velocity occurred was changing gradually when the pressure at the exhaust hood inlet changed from 0 Pa to -5 Pa.

  20. Flow-Field Characteristics of High-Temperature Annular Buoyant Jets and Their Development Laws Influenced by Ventilation System

    PubMed Central

    Liu, Jiaping; Wang, Hai; Liu, Qiuhan

    2013-01-01

    The flow-field characteristics of high-temperature annular buoyant jets as well as the development laws influenced by ventilation system were studied using numerical methods to eliminate the pollutants effectively in this paper. The development laws of high-temperature annular buoyant jets were analyzed and compared with previous studies, including radial velocity distribution, axial velocity and temperature decay, reattachment position, cross-section diameter, volumetric flow rate, and velocity field characteristics with different pressures at the exhaust hood inlet. The results showed that when the ratio of outer diameter to inner diameter of the annulus was smaller than 5/2, the flow-field characteristics had significant difference compared to circular buoyant jets with the same outer diameter. For similar diameter ratios, reattachment in this paper occurred further downstream in contrast to previous study. Besides, the development laws of volumetric flow rate and cross-section diameter were given with different initial parameters. In addition, through analyzing air distribution characteristics under the coupling effect of high-temperature annular buoyant jets and ventilation system, it could be found that the position where maximum axial velocity occurred was changing gradually when the pressure at the exhaust hood inlet changed from 0 Pa to −5 Pa. PMID:24000278

  1. A new contrast-assisted method in microcirculation volumetric flow assessment

    NASA Astrophysics Data System (ADS)

    Lu, Sheng-Yi; Chen, Yung-Sheng; Yeh, Chih-Kuang

    2007-03-01

    Microcirculation volumetric flow rate is a significant index in diseases diagnosis and treatment such as diabetes and cancer. In this study, we propose an integrated algorithm to assess microcirculation volumetric flow rate including estimation of blood perfused area and corresponding flow velocity maps based on high frequency destruction/contrast replenishment imaging technique. The perfused area indicates the blood flow regions including capillaries, arterioles and venules. Due to the echo variance changes between ultrasonic contrast agents (UCAs) pre- and post-destruction two images, the perfused area can be estimated by the correlation-based approach. The flow velocity distribution within the perfused area can be estimated by refilling time-intensity curves (TICs) after UCAs destruction. Most studies introduced the rising exponential model proposed by Wei (1998) to fit the TICs. Nevertheless, we found the TICs profile has a great resemblance to sigmoid function in simulations and in vitro experiments results. Good fitting correlation reveals that sigmoid model was more close to actual fact in describing destruction/contrast replenishment phenomenon. We derived that the saddle point of sigmoid model is proportional to blood flow velocity. A strong linear relationship (R = 0.97) between the actual flow velocities (0.4-2.1 mm/s) and the estimated saddle constants was found in M-mode and B-mode flow phantom experiments. Potential applications of this technique include high-resolution volumetric flow rate assessment in small animal tumor and the evaluation of superficial vasculature in clinical studies.

  2. A novel, microscope based, non invasive Laser Doppler flowmeter for choroidal blood flow assessment

    PubMed Central

    Strohmaier, C; Werkmeister, RM; Bogner, B; Runge, C; Schroedl, F; Brandtner, H; Radner, W; Schmetterer, L; Kiel, JW; Grabnerand, G; Reitsamer, HA

    2015-01-01

    Impaired ocular blood flow is involved in the pathogenesis of numerous ocular diseases like glaucoma or AMD. The purpose of the present study was to introduce and validate a novel, microscope based, non invasive laser Doppler flowmeter (NILDF) for measurement of blood flow in the choroid. The custom made NI-LDF was compared with a commercial fiber optic based laser Doppler flowmeter (Perimed PF4000). Linearity and stability of the NI-LDF were assessed in a silastic tubing model (i.d. 0.3 mm) at different flow rates (range 0.4 – 3 ml/h). In a rabbit model continuous choroidal blood flow measurements were performed with both instruments simultaneously. During blood flow measurements ocular perfusion pressure was changed by manipulations of intraocular pressure via intravitreal saline infusions. The NILDF measurement correlated linearly to intraluminal flow rates in the perfused tubing model (r = 0.99, p<0.05) and remained stable during a 1 hour measurement at a constant flow rate. Rabbit choroidal blood flow measured by the PF4000 and the NI-LDF linearly correlated with each other over the entire measurement range (r = 0.99, y = x* 1,01 – 12,35 P.U., p < 0,001). In conclusion, the NI-LDF provides valid, semi quantitative measurements of capillary blood flow in comparison to an established LDF instrument and is suitable for measurements at the posterior pole of the eye. PMID:21443871

  3. Geomorphic Change Induced by 100 years of Flow Alteration on the Diamond Fork River, Central Utah

    NASA Astrophysics Data System (ADS)

    Jones, J.; Belmont, P.; Wilcock, P. R.

    2017-12-01

    Changes in hydrology and sediment supply affect the form of rivers. The rate of change of fluvial form is controlled by a variety of factors, including valley confinement, sediment size, and antecedent condition. The Diamond Fork River in central Utah has been altered by trans-basin flows delivered from the Colorado River system for over a century. Beginning in 1915, water used for irrigation was delivered through a tributary, Sixth Water Creek, with daily summer flows regularly exceeding the 50 - 100 year flood. Elevated flows caused drastic geomorphic change - resulting in incision and widening of the channel, and the destruction of riparian vegetation. Beginning in 1997, the outlet for the trans-basin diversion was moved downstream on Sixth Water, bypassing a large landslide, and flows were drastically reduced in 2004 through management actions. We delineated eight distinct process domains for the Sixth Water-Diamond Fork system and examined the response of each process domain to the altered flow and sediment regimes through the analysis of aerial photographs and repeat cross-sections. We measured a variety of channel metrics, including channel width, areal extent of bars and islands, and sinuosity in ArcGIS. Results indicate that unconfined reaches that were wide and braided during the period of elevated flows have narrowed to become single threaded and meandering in response to the reduced flows. Confined reaches have experienced minor changes since the reduction in flows, suggesting that confinement is a primary control on the degree of channel response. These findings and complimentary studies will provide managers of Sixth Water and Diamond Fork with a greater understanding of the physical response of the streams, and the resulting effects on ecological communities.

  4. Near-wall modeling of compressible turbulent flow

    NASA Technical Reports Server (NTRS)

    So, Ronald M. C.

    1991-01-01

    A near-wall two-equation model for compressible flows is proposed. The model is formulated by relaxing the assumption of dynamic field similarity between compressible and incompressible flows. A postulate is made to justify the extension of incompressible models to ammount for compressibility effects. This requires formulation the turbulent kinetic energy equation in a form similar to its incompressible counterpart. As a result, the compressible dissipation function has to be split into a solenoidal part, which is not sensitive to changes of compressibility indicators, and a dilatational part, which is directly affected by these changes. A model with an explicit dependence on the turbulent Mach number is proposed for the dilatational dissipation rate.

  5. Decomposition behavior of hemicellulose and lignin in the step-change flow rate liquid hot water.

    PubMed

    Zhuang, Xinshu; Yu, Qiang; Wang, Wen; Qi, Wei; Wang, Qiong; Tan, Xuesong; Yuan, Zhenhong

    2012-09-01

    Hemicellulose and lignin are the main factors limiting accessibility of hydrolytic enzymes besides the crystallinity of cellulose. The decomposition behavior of hemicellulose and lignin in the step-change flow rate hot water system was investigated. Xylan removal increased from 64.53% for batch system (solid concentration 4.25% w/v, 18 min, 184°C) to 83.78% at high flow rates of 30 ml/min for 8 min, and then 10 ml/min for 10 min. Most of them (80-90%) were recovered as oligosaccharide. It was hypothesized that the flowing water could enhance the mass transfer to improve the sugars recovery. In addition, the solubilization mechanism of lignin in the liquid hot water was proposed according to the results of Fourier transform-infrared spectroscopy and scanning electron microscopy of the water-insoluble fraction and gas chromatography-mass spectrometry of the water-soluble fraction. It was proposed that lignin in the liquid hot water first migrated out of the cell wall in the form of molten bodies, and then flushed out of the reactor. A small quantity of them was further degraded into monomeric products such as vanillin, syringe aldehyde, coniferyl aldehyde, ferulic acid, and p-hydroxy-cinnamic acid. All of these observations would provide important information for the downstream processing, such as purification and concentration of sugars and the enzymatic digestion of residual solid.

  6. Evidence for enhanced debris-flow activity in the Northern Calcareous Alps since the 1980s (Plansee, Austria)

    NASA Astrophysics Data System (ADS)

    Dietrich, A.; Krautblatter, M.

    2017-06-01

    Debris flows are among the most important natural hazards. The Northern Calcareous Alps with their susceptible lithology are especially affected by a double digit number of major hazard events per year. It is hypothesised that debris-flow intensity has increased significantly in the last decades in the Northern Calcareous Alps coincident to increased rainstorm frequencies, but yet there is only limited evidence. The Plansee catchment exposes extreme debris-flow activity due to the intensely jointed Upper Triassic Hauptdolomit lithology, being responsible for most of the debris-flow activity in the Northern Calcareous Alps. The debris flows feed into a closed sediment system, the Plansee Lake, where Holocene/Lateglacial sedimentation rates, rates since the late 1940s and recent rates can be inferred accurately. Using aerial photos and field mapping, the temporal and spatial development of eight active debris-flow fans is reconstructed in six time intervals from 1947, 1952, 1971, 1979, 1987, 2000 and 2010 and mean annual debris-flow volumes are calculated. These are compared with mean Holocene/Lateglacial debris-flow volumes derived from the most prominent cone whose contact with the underlying till is revealed by electrical resistivity tomography (ERT). Debris-flow activity there increased by a factor of 10 from 1947-1952 (0.23 ± 0.07 · 103 m3/yr) to 1987-2000 (2.41 ± 0.66 · 103 m3/yr). Mean post-1980 rates from all eight fans exceed pre-1980 rates by a factor of more than three coinciding with enhanced rainstorm activity recorded at meteorological stations in the Northern Calcareous Alps. The frequency of rain storms (def. 35 mm/d) has increased in the study area on average by 10% per decade and has nearly doubled since 1921. Recent debris-flow activity is also 2-3 times higher than mean Holocene/Lateglacial rates. The strong correlation between the non-vegetated catchment area and the annual debris-flow volume might indicate a decadal positive feedback between enhanced rainstorm activity and debris flows. Here we investigate the temporal and spatial development of debris-flow fans to better understand the sensitivity of alpine catchments to heavy rainfall events in the context of climate change. n.m. = not measurable.

  7. HISTORICAL CHANGES IN GLOBAL SCALE CIRCULATION PATTERNS, MID-ATLANTIC CLIMATE STREAM FLOW AND NUTRIENT FLUXES TO THE CHESAPEAKE BAY

    EPA Science Inventory

    The rate of change in Northern Hemisphere temperature in the past century strongly suggests that we are now in a period of rapid global climate change. Also, the climate in the mid-Atlantic is quite sensitive to larger scale climate variation, which affects the frequency and seve...

  8. Icebergs Melting in Uniform and Vertically Sheared Flows

    NASA Astrophysics Data System (ADS)

    Cenedese, Claudia; Fitzmaurice, Anna; Straneo, Fiammetta

    2017-11-01

    Icebergs calving into Greenlandic Fjords frequently experience strongly sheared flows over their draft, but the impact of this flow past the iceberg on the melt plumes generated along the iceberg sides is not fully captured by existing melt parameterizations. A series of novel laboratory experiments showed that side melting of icebergs subject to relative velocities is controlled by two distinct regimes, which depend on the melt plume behavior (side-attached or side-detached). These two regimes produce a nonlinear dependence of melt rate on velocity, and different distributions of meltwater in the water column. Iceberg meltwater may either be confined to a thin surface layer, when the melt plumes are side-attached, or mixed down to the iceberg draft, when the melt plumes are side-detached. In a two-layer vertically sheared flow, the average flow speed in existing melt parameterizations gives an underestimate of the submarine melt rate, in part due to the nonlinearity of the dependence of melt rate on flow speed, but also because vertical shear in the velocity profile fundamentally changes the flow splitting around the ice block and consequently the velocity felt by the ice surface. Including this nonlinear velocity dependence in melting parameterizations applied to observed icebergs increases iceberg side melt in the side-attached regime, improving agreement with observations of iceberg submarine melt rates. AF was supported by NA14OAR4320106, CC by NSF OCE-1434041 and OCE-1658079, and FS by NSF PLR-1332911 and OCE-1434041.

  9. Performance analysis of a new hypersonic vitrector system.

    PubMed

    Stanga, Paulo Eduardo; Pastor-Idoate, Salvador; Zambrano, Isaac; Carlin, Paul; McLeod, David

    2017-01-01

    To evaluate porcine vitreous flow and water flow rates in a new prototype hypersonic vitrectomy system compared to currently available pneumatic guillotine vitrectors (GVs) systems. Two vitrectors were tested, a prototype, ultrasound-powered, hypersonic vitrector (HV) and a GV. Porcine vitreous was obtained within 12 to 24 h of sacrifice and kept at 4°C. A vial of vitreous or water was placed on a precision balance and its weight measured before and after the use of each vitrector. Test parameters included changes in aspiration levels, vitrector gauge, cut rates for GVs, % ultrasound (US) power for HVs, and port size for HVs. Data was analysed using linear regression and t-tests. There was no difference in the total average mean water flow between the 25-gauge GV and the 25-gauge HV (t-test: P = 0.363); however, 25-gauge GV was superior (t-test: P < 0.001) in vitreous flow. The 23-gauge GV was only more efficient in water and vitreous removal than 23-gauge HV needle-1 (Port 0.0055) (t-test: P < 0.001). For HV, wall thickness and gauge had no effect on flow rates. Water and vitreous flows showed a direct correlation with increasing aspiration levels and % US power (p<0.05). The HV produced consistent water and vitreous flow rates across the range of US power and aspiration levels tested. Hypersonic vitrectomy may be a promising new alternative to the currently available guillotine-based technologies.

  10. Xerostomia, salivary characteristics and gland volumes following intensity-modulated radiotherapy for nasopharyngeal carcinoma: a two-year follow up.

    PubMed

    Sim, Cpc; Soong, Y L; Pang, Epp; Lim, C; Walker, G D; Manton, D J; Reynolds, E C; Wee, Jts

    2018-06-01

    To evaluate changes in xerostomia status, salivary characteristics and gland volumes 2 years following radiotherapy in nasopharyngeal carcinoma patients. Xerostomia scores, salivary flow rates, pH and buffering capacity were measured at pre-radiotherapy, mid-radiotherapy, 2 weeks, 3 months and 2 years post-radiotherapy. Salivary gland volumes and their correlation with radiation dose were also assessed. Mean radiation dose to oral cavity, parotid and submandibular glands (SMG) was 44.5, 65.0 and 38.6 Gy respectively. Parotid and SMG volumes decreased 33% at 3 months post-radiotherapy; volumes at 2 years post-radiotherapy were 84% and 51% of pre-radiotherapy levels, respectively. Correlations were observed between parotid gland volume per cent reduction and its radiation dose and between resting salivary flow rate reduction and post-radiotherapy/pre-radiotherapy SMG volume ratio. Salivary flow rates and resting saliva pH remained significantly low at 2 years post-radiotherapy (both flow rates, P = 0.001; resting saliva pH, P = 0.005). Similarly, xerostomia scores remained significantly higher compared with pre-radiotherapy levels. Submandibular gland volumetric shrinkage persisted 2 years after radiotherapy. Xerostomia scores remained significantly higher, and salivary flow rates and resting saliva pH remained significantly lower, suggesting that study participants were still at risk for hyposalivation-related oral diseases. © 2018 Australian Dental Association.

  11. Spatial and Temporal Patterns of Dissolved Organic Matter Characteristics in the Upper Willamette River Basin, Oregon

    NASA Astrophysics Data System (ADS)

    Lee, B. S.; Lajtha, K.

    2014-12-01

    Dissolved organic matter (DOM) leaching through soil affects soil carbon sequestration and the carbon metabolism of receiving water bodies. Improving our understanding of the sources and fate of DOM at varying spatial and temporal patterns is crucial for land management decisions. However, little is known about how DOM sources change with land use types and seasonal flow patterns. In the Willamette River Basin (WRB), which is home to Oregon's major cities including Portland and Salem, forested headwaters transition to agricultural and urban land. The climate of WRB has a distinctive seasonal pattern with dry warm summers and wet winters driven by winter precipitation and snowmelt runoff between November and March. This study examined DOM fluorescence characteristic in stream water from 21 locations collected monthly and 16 locations collected seasonally to identify the sources and fate of DOM in the upper WRB in contrasting land uses. DOC and dissolved organic nitrogen concentrations increased as the flow rate increased during winter precipitation at all sites. This indicates that increased flow rate increased the connectivity between land and nearby water bodies. DOM fluorescent properties varied among land use types. During the first precipitation event after a long dry summer, a microbial DOM signature in agricultural areas increased along with nitrate concentrations. This may be because accumulated nutrients on land during the dry season flowed to nearby streams during the first rain event and promoted microbial growth in the streams. During the month of the highest flow rate in 2014, sampling sites near forest showed evidence of a greater terrestrial DOM signature compared to its signature during the dry season. This indicates fluorescent DOM characteristics in streams vary as the flow connectivity changes even within the same land type.

  12. Effects of surface-water and groundwater inflows and outflows on the hydrology of the Tsala Apopka Lake Basin in Citrus County, Florida

    USGS Publications Warehouse

    Sepúlveda, Nicasio; Fulkerson, Mark; Basso, Ron; Ryan, Patrick J.

    2018-05-21

    The U.S. Geological Survey, in cooperation with the Southwest Florida Water Management District, initiated a study to quantify the inflows and outflows in the Floral City, Inverness, and Hernando pools of the Tsala Apopka Lake Basin in Citrus County, Florida. This study assesses hydrologic changes in pool stages, groundwater levels, spring flows, and streamflows caused by the diversion of streamflow from the Withlacoochee River to the Tsala Apopka Lake Basin through water-control structures. A surface-water/groundwater flow model was developed using hydraulic parameters for lakes, streams, the unsaturated zone, and the underlying surficial and Upper Floridan aquifers estimated using an inverse modeling calibration technique. After calibration, the model was used to assess the relation between inflows and outflows in the Tsala Apopka Lake Basin and changes in pool stages.Simulation results using the calibrated surface-water/groundwater flow model showed that leakage rates from the pools to the Upper Floridan aquifer were largest at the deep lake cells and that these leakage rates to the Upper Floridan aquifer were the highest in the model area. Downward leakage to the Upper Floridan aquifer occurred beneath most of the extent of the Floral City, Inverness, and Hernando pools. These leakage rates depended on the lakebed leakance and the difference between lake stages and heads in the Upper Floridan aquifer. Leakage rates were higher for the Floral City pool than for the Inverness pool, and higher for the Inverness pool than for the Hernando pool. Lakebed leakance was higher for the Floral City pool than for the Hernando pool, and higher for the Hernando pool than for the Inverness pool.Simulation results showed that the average recharge rate to the surficial aquifer was 10.3 inches per year for the 2004 to 2012 simulation period. Areas that recharge the surficial aquifer covered about 86 percent of the model area. Simulations identified areas along segments of the Withlacoochee River and within land-surface depressions that receive water from the surficial aquifer. Recharge rates were largest in physiographic regions having a deep water table. Simulated heads in the Upper Floridan aquifer indicated the general flow directions in the active flow model area were from the northeast toward the southwest and then westward toward the coast, and from the southeast toward the northwest and then westward toward the coast, consistent with flow directions inferred from the estimated potentiometric surface map for May 2010. The largest inflow in the water budget of the Upper Floridan aquifer was downward leakage from the overlying hydrogeologic unit. The largest outflow in the water budget of the Upper Floridan aquifer was spring flow.The calibrated surface-water and groundwater flow model was used to simulate hydrologic scenarios that included changes in rainfall rates, projected increases in groundwater pumping rates for 2025 and 2035, no flow for the 2004–12 period through the eight water-control structures in the Tsala Apopka Lake Basin, and the removal of the Inglis Dam and the Inglis Bypass Spillway on Lake Rousseau. Scenario simulation results were compared to annual average calibrated water levels and flows from 2004 to 2012. Simulated declines in the Tsala Apopka Lake pool stages under the 10-percent lower rainfall scenario were about 0.8, 0.3, and 1.3 feet (ft) for the Floral City, Inverness, and Hernando pools, respectively. Simulated groundwater levels under the same scenario declined up to 5.4 ft in the surficial aquifer and up to 2.9 ft in the Upper Floridan aquifer. Under the projected increases in groundwater pumping rates for 2035 that represented an increase of 36 percent from average 2004 to 2012 pumping rates, the simulated declines in the Floral City, Inverness, and Hernando pool stages were, in downstream order, 0.02, 0.06, and 0.04 ft. The largest drawdown under the projected increases in groundwater pumping rates for 2035 was 2.1 ft in the surficial aquifer and about 1.8 ft in the Upper Floridan aquifer. A scenario of decreased rainfall by 10 percent caused greater declines in water levels and pool stages than projected increases in groundwater pumping rates. The simulation with no flow through the eight Tsala Apopka Lake water-control structures resulted in simulated declines in average pool stage of 1.8, 1.9, and 0.5 ft in the Floral City, Inverness, and Hernando pools, respectively. The simulated removal of the two water-control structures in Lake Rousseau caused flow to increase at Rainbow Springs by 28 cubic feet per second, an increase of 4.7 percent from the average calibrated flow for 2004 to 2012.

  13. 40 CFR 1065.1107 - Sample media and sample system preparation; sample system assembly.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...) For capturing PM, we recommend using pure quartz filters with no binder. Select the filter diameter to minimize filter change intervals, accounting for the expected PM emission rate, sample flow rate, and... filter without replacing the sorbent or otherwise disassembling the batch sampler. In those cases...

  14. Three-dimensional numerical simulation of water droplet emerging from a gas diffusion layer surface in micro-channels

    NASA Astrophysics Data System (ADS)

    Ding, Y.; Bi, H. T.; Wilkinson, D. P.

    The dynamic formation of water droplets emerging from a gas diffusion layer (GDL) surface in micro-channels was simulated using the volume of fluid (VOF) method. The influence of GDL surface microstructure was investigated by changing the pore diameter and the number of pore openings on the GDL surface. Simulation results show that the microstructure of the GDL surface has a significant impact on the two-phase flow patterns in gas flow channels. For a non-uniform GDL surface, three stages were identified, namely emergence and merging on the GDL surface, accumulation on the channel sidewalls and detachment from the top wall. It was also found that if the pore size is small enough, the flow pattern in the channel does not change with further reduction in the pore diameter. However, the two-phase flow patterns change significantly with the wettability of the GDL surface and sidewalls, but remain the same when the liquid flow rate is reduced by two orders of magnitude from the reference case.

  15. Effect of simulated hyperemia on the flow field in a mildly atherosclerotic coronary artery casting of man

    NASA Technical Reports Server (NTRS)

    Cho, Y. I.; Back, L. H.; Crawford, D. W.

    1985-01-01

    Changes in an arterial flow field due to mild atherosclerosis were determined using a main coronary artery casting with a maximum obstruction of about 50 percent by area. Local pressure changes were measured using six pressure tap holes along the wall of the casting. The test-fluid was a 33 percent sugar-water solution of approximately the same viscosity as human blood. Flow visualization results were obtained by injecting blue-dye through the pressure tap holes. Measurement of local pressure demonstrated a significant Reynolds number effect. At Reynolds numbers of 80-710, a local pressure rise was observed downstream of the mild atherosclerotic constriction due to momentum changes. The Reynolds number necessary for flow separation in the divergent region of the coronary casting was about 330. The experimental results can be used to obtain a quantitative relation between coronary morphology and the fluid dynamic consequences of mild diffuse disease under conditions of maximum cardiac demand i.e., higher coronary flow rates and Reynolds numbers associated with space and atmospheric flight.

  16. Correlated Temporal and Spectral Variability

    NASA Technical Reports Server (NTRS)

    Swank, Jean H.

    2007-01-01

    The variability of neutron star and black hole X-ray sources has several dimensions, because of the roles played by different important time-scales. The variations on time scales of hours, weeks, and months, ranging from 50% to orders of magnitude, arise out of changes in the flow in the disk. The most important driving forces for those changes are probably various possible instabilities in the disk, though there may be effects with other dominant causes. The changes in the rate of flow appear to be associated with changes in the flow's configuration, as the accreting material approaches the compact object, for there are generally correlated changes in both the Xray spectra and the character of the faster temporal variability. There has been a lot of progress in tracking these correlations, both for Z and Atoll neutron star low-mass X-ray binaries, and for black hole binaries. I will discuss these correlations and review briefly what they tell us about the physical states of the systems.

  17. Climate change impact on infection risks during bathing downstream of sewage emissions from CSOs or WWTPs.

    PubMed

    Sterk, Ankie; de Man, Heleen; Schijven, Jack F; de Nijs, Ton; de Roda Husman, Ana Maria

    2016-11-15

    Climate change is expected to influence infection risks while bathing downstream of sewage emissions from combined sewage overflows (CSOs) or waste water treatment plants (WWTPs) due to changes in pathogen influx, rising temperatures and changing flow rates of the receiving waters. In this study, climate change impacts on the surface water concentrations of Campylobacter, Cryptosporidium and norovirus originating from sewage were modelled. Quantitative microbial risk assessment (QMRA) was used to assess changes in risks of infection. In general, infection risks downstream of WWTPs are higher than downstream CSOs. Even though model outputs show an increase in CSO influxes, in combination with changes in pathogen survival, dilution within the sewage system and bathing behaviour, the effects on the infection risks are limited. However, a decrease in dilution capacity of surface waters could have significant impact on the infection risks of relatively stable pathogens like Cryptosporidium and norovirus. Overall, average risks are found to be higher downstream WWTPs compared to CSOs. Especially with regard to decreased flow rates, adaptation measures on treatment at WWTPs may be more beneficial for human health than decreasing CSO events. Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.

  18. Dynamic reservoir-condition microtomography of reactive transport in complex carbonates: Effect of initial pore structure and initial brine pH

    NASA Astrophysics Data System (ADS)

    Menke, H. P.; Bijeljic, B.; Blunt, M. J.

    2017-05-01

    We study the impact of brine acidity and initial pore structure on the dynamics of fluid/solid reaction at high Péclet numbers and low Damköhler numbers. A laboratory μ-CT scanner was used to image the dissolution of Ketton, Estaillades, and Portland limestones in the presence of CO2-acidified brine at reservoir conditions (10 MPa and 50 °C) at two injected acid strengths for a period of 4 h. Each sample was scanned between 6 and 10 times at ∼4 μm resolution and multiple effluent samples were extracted. The images were used as inputs into flow simulations, and analysed for dynamic changes in porosity, permeability, and reaction rate. Additionally, the effluent samples were used to verify the image-measured porosity changes. We find that initial brine acidity and pore structure determine the type of dissolution. Dissolution is either uniform where the porosity increases evenly both spatially and temporally, or occurs as channelling where the porosity increase is concentrated in preferential flow paths. Ketton, which has a relatively homogeneous pore structure, dissolved uniformly at pH = 3.6 but showed more channelized flow at pH = 3.1. In Estaillades and Portland, increasingly complex carbonates, channelized flow was observed at both acidities with the channel forming faster at lower pH. It was found that the effluent pH, which is higher than that injected, is a reasonably good indicator of effective reaction rate during uniform dissolution, but a poor indicator during channelling. The overall effective reaction rate was up to 18 times lower than the batch reaction rate measured on a flat surface at the effluent pH, with the lowest reaction rates in the samples with the most channelized flow, confirming that transport limitations are the dominant mechanism in determining reaction dynamics at the fluid/solid boundary.

  19. The role of angiotensin II in the renal responses to somatic nerve stimulation in the rat.

    PubMed Central

    Handa, R K; Johns, E J

    1987-01-01

    1. Electrical stimulation of the brachial nerves at 3 Hz (15 V, 0.2 ms), in sodium pentobarbitone-anaesthetized rats whose renal arterial pressure was held constant, elicited a 26% increase in systemic blood pressure, a 15% rise in heart rate, an 11% reduction in renal blood flow, did not alter glomerular filtration rate and significantly reduced absolute and fractional sodium excretions and urine flow by 44, 49 and 31%, respectively. 2. In a separate group of rats, brachial nerve stimulation at 3 Hz increased plasma renin activity approximately 2-fold, while in animals in which the brachial nerves were not stimulated plasma renin activity did not change. 3. Following inhibition of the renin-angiotensin system with captopril or sar-1-ile-8-angiotensin II, brachial nerve stimulation resulted in similar increases in systemic blood pressure and heart rate as in the animals with an intact renin-angiotensin system but, in captopril-infused rats, did not change renal haemodynamics or urine flow while absolute and fractional sodium excretions were reduced by 20 and 25%, respectively. In sar-1-ile-8-angiotensin II-infused animals, similar nerve stimulation decreased renal blood flow by 12%, glomerular filtration rate by 7% and absolute and fractional sodium excretions and urine flow by 25, 18 and 18%, respectively. These decreases in sodium and water output were significantly smaller than those observed in animals with an intact renin-angiotensin system. 4. Stimulation of the brachial nerves increased post-ganglionic efferent renal nerve activity by 20% and the magnitude of this response was unaffected following inhibition of the renin-angiotensin system. 5. The results show that low rates of brachial nerve stimulation in the rat can increase efferent renal nerve activity and result in an antinatriuresis and antidiuresis which is dependent on the presence of angiotensin II, and appears to be due to an action of angiotensin II at the level of the kidney. PMID:3328780

  20. Temporal downscaling of decadal sediment load estimates to a daily interval for use in hindcast simulations

    USGS Publications Warehouse

    Ganju, N.K.; Knowles, N.; Schoellhamer, D.H.

    2008-01-01

    In this study we used hydrologic proxies to develop a daily sediment load time-series, which agrees with decadal sediment load estimates, when integrated. Hindcast simulations of bathymetric change in estuaries require daily sediment loads from major tributary rivers, to capture the episodic delivery of sediment during multi-day freshwater flow pulses. Two independent decadal sediment load estimates are available for the Sacramento/San Joaquin River Delta, California prior to 1959, but they must be downscaled to a daily interval for use in hindcast models. Daily flow and sediment load data to the Delta are available after 1930 and 1959, respectively, but bathymetric change simulations for San Francisco Bay prior to this require a method to generate daily sediment load estimates into the Delta. We used two historical proxies, monthly rainfall and unimpaired flow magnitudes, to generate monthly unimpaired flows to the Sacramento/San Joaquin Delta for the 1851-1929 period. This step generated the shape of the monthly hydrograph. These historical monthly flows were compared to unimpaired monthly flows from the modern era (1967-1987), and a least-squares metric selected a modern water year analogue for each historical water year. The daily hydrograph for the modern analogue was then assigned to the historical year and scaled to match the flow volume estimated by dendrochronology methods, providing the correct total flow for the year. We applied a sediment rating curve to this time-series of daily flows, to generate daily sediment loads for 1851-1958. The rating curve was calibrated with the two independent decadal sediment load estimates, over two distinct periods. This novel technique retained the timing and magnitude of freshwater flows and sediment loads, without damping variability or net sediment loads to San Francisco Bay. The time-series represents the hydraulic mining period with sustained periods of increased sediment loads, and a dramatic decrease after 1910, corresponding to a reduction in available mining debris. The analogue selection procedure also permits exploration of the morphological hydrograph concept, where a limited set of hydrographs is used to simulate the same bathymetric change as the actual set of hydrographs. The final daily sediment load time-series and morphological hydrograph concept will be applied as landward boundary conditions for hindcasting simulations of bathymetric change in San Francisco Bay.

  1. The Anatomy of the Blue Dragon: Changes in Lava Flow Morphology and Physical Properties Observed in an Open Channel Lava Flow as a Planetary Analogue

    NASA Astrophysics Data System (ADS)

    Sehlke, A.; Kobs-Nawotniak, S. E.; Hughes, S. S.; Sears, D. W. G.; Downs, M.; Whittington, A. G.; Lim, D. S. S.; Heldmann, J. L.

    2017-12-01

    Lava terrains on other planets and moons exhibit morphologies similar to those found on Earth, such as smooth pāhoehoe transitioning to rough `a`ā terrains based on the viscosity - strain rate relationship of the lava. Therefore, the morphology of lava flows is governed by eruptive conditions such as effusion rate, underlying slope, and the fundamental thermo-physical properties of the lava, including temperature (T), composition (X), viscosity (η), fraction of crystals (φc) and vesicles (φb), as well as bulk density (ρ). These textural and rheological changes were previously studied for Hawaiian lava, where the lava flow started as channelized pāhoehoe and transitioned into `a`ā, demonstrating a systematic trend in T, X, η, φc, φb, and ρ. NASA's FINESSE focuses on Science and Exploration through analogue research. One of the field sites is Craters of the Moon, Idaho. We present field work done at a 3.0 km long lava flow belonging to the Blue Dragon lavas erupted from a chain of spatter cones, which then coalesced into channelized flows. We acquired UAV imagery along the entire length of the flow, and generated a high resolution DTM of 5 cm/pixel, from which we derived height profiles and surface roughness values. Field work included mapping the change in surface morphology and sample collection every 150 meters. In the laboratory, we measured φc, φb, and ρ for all collected samples. Viscosity measurements were carried out by concentric cylinder viscometry at subliquidus temperatures between 1310ºC to 1160ºC to study the rheology of the lava, enabling us to relate changes in flow behavior to T and φc. Our results are consistent with observations made for Hawaiian lava, including increasing bulk density downflow, and porosity changing from connected to isolated pore space. Crystallinity increases downflow, and the transition from pāhoehoe to `a`ā occurs between 1230ºC to 1150ºC, which is prompted by nucleation and growth of plagioclase microcrystals, strongly increasing the viscosity of the lava several orders of magnitude. The results of this study allows us to correlate T, X, η, φc, φb, and ρ to the lava flow morphology expressed as surface roughness, which can then be used as a tool to infer these physical properties of the rocks for open channel lava flows on other airless bodies, such as the Moon and Mercury, based on DTMs.

  2. Increased Regurgitant Flow Causes Endocardial Cushion Defects in an Avian Embryonic Model of Congenital Heart Disease

    PubMed Central

    Ford, Stephanie M; McPheeters, Matthew T; Wang, Yves T; Ma, Pei; Gu, Shi; Strainic, James; Snyder, Christopher; Rollins, Andrew M; Watanabe, Michiko; Jenkins, Michael W

    2017-01-01

    Background The relationship between changes in endocardial cushion and resultant congenital heart diseases (CHD) has yet to be established. It has been shown that increased regurgitant flow early in embryonic heart development leads to endocardial cushion defects, but it remains unclear how abnormal endocardial cushions during the looping stages might affect the fully septated heart. The goal of this study was to reproducibly alter blood flow in vivo and then quantify the resultant effects on morphology of endocardial cushions in the looping heart and on CHDs in the septated heart. Methods Optical pacing was applied to create regurgitant flow in embryonic hearts, and optical coherence tomography (OCT) was utilized to quantify regurgitation and morphology. Embryonic quail hearts were optically paced at 3 Hz (180bpm, well above intrinsic rate 60–110bpm) at stage 13 of development (3–4 wks human) for 5 min. Pacing fatigued the heart and led to at least 1 hr of increased regurgitant flow. Resultant morphological changes were quantified with OCT imaging at stage 19 (cardiac looping – 4–5 wks human) or stage 35 (4 chambered heart – 8 wks human). Results All paced embryos imaged at stage 19 displayed structural changes in cardiac cushions. The amount of regurgitant flow immediately after pacing was inversely correlated with cardiac cushion size 24-hrs post pacing (p-value < 0.01). The embryos with the most regurgitant flow and smallest cushions after pacing had a decreased survival rate at 8 days (p<0.05), indicating that those most severe endocardial cushion defects were lethal. Of the embryos that survived to stage 35, 17/18 exhibited CHDs including valve defects, ventricular septal defects, hypoplastic ventricles, and common AV canal. Conclusion The data illustrate a strong inverse relationship in which regurgitant flow precedes abnormal and smaller cardiac cushions, resulting in the development of CHDs. PMID:28211263

  3. Identification of aerodynamic models for maneuvering aircraft

    NASA Technical Reports Server (NTRS)

    Chin, Suei; Lan, C. Edward

    1990-01-01

    Due to the requirement of increased performance and maneuverability, the flight envelope of a modern fighter is frequently extended to the high angle-of-attack regime. Vehicles maneuvering in this regime are subjected to nonlinear aerodynamic loads. The nonlinearities are due mainly to three-dimensional separated flow and concentrated vortex flow that occur at large angles of attack. Accurate prediction of these nonlinear airloads is of great importance in the analysis of a vehicle's flight motion and in the design of its flight control system. A satisfactory evaluation of the performance envelope of the aircraft may require a large number of coupled computations, one for each change in initial conditions. To avoid the disadvantage of solving the coupled flow-field equations and aircraft's motion equations, an alternate approach is to use a mathematical modeling to describe the steady and unsteady aerodynamics for the aircraft equations of motion. Aerodynamic forces and moments acting on a rapidly maneuvering aircraft are, in general, nonlinear functions of motion variables, their time rate of change, and the history of maneuvering. A numerical method was developed to analyze the nonlinear and time-dependent aerodynamic response to establish the generalized indicial function in terms of motion variables and their time rates of change.

  4. Interaction of dihydrofolate reductase with methotrexate: Ensemble and single-molecule kinetics

    NASA Astrophysics Data System (ADS)

    Rajagopalan, P. T. Ravi; Zhang, Zhiquan; McCourt, Lynn; Dwyer, Mary; Benkovic, Stephen J.; Hammes, Gordon G.

    2002-10-01

    The thermodynamics and kinetics of the interaction of dihydrofolate reductase (DHFR) with methotrexate have been studied by using fluorescence, stopped-flow, and single-molecule methods. DHFR was modified to permit the covalent addition of a fluorescent molecule, Alexa 488, and a biotin at the N terminus of the molecule. The fluorescent molecule was placed on a protein loop that closes over methotrexate when binding occurs, thus causing a quenching of the fluorescence. The biotin was used to attach the enzyme in an active form to a glass surface for single-molecule studies. The equilibrium dissociation constant for the binding of methotrexate to the enzyme is 9.5 nM. The stopped-flow studies revealed that methotrexate binds to two different conformations of the enzyme, and the association and dissociation rate constants were determined. The single-molecule investigation revealed a conformational change in the enzyme-methotrexate complex that was not observed in the stopped-flow studies. The ensemble averaged rate constants for this conformation change in both directions is about 2-4 s1 and is attributed to the opening and closing of the enzyme loop over the bound methotrexate. Thus the mechanism of methotrexate binding to DHFR involves multiple steps and protein conformational changes.

  5. Stall/surge dynamics of a multi-stage air compressor in response to a load transient of a hybrid solid oxide fuel cell-gas turbine system

    NASA Astrophysics Data System (ADS)

    Azizi, Mohammad Ali; Brouwer, Jacob

    2017-10-01

    A better understanding of turbulent unsteady flows in gas turbine systems is necessary to design and control compressors for hybrid fuel cell-gas turbine systems. Compressor stall/surge analysis for a 4 MW hybrid solid oxide fuel cell-gas turbine system for locomotive applications is performed based upon a 1.7 MW multi-stage air compressor. Control strategies are applied to prevent operation of the hybrid SOFC-GT beyond the stall/surge lines of the compressor. Computational fluid dynamics tools are used to simulate the flow distribution and instabilities near the stall/surge line. The results show that a 1.7 MW system compressor like that of a Kawasaki gas turbine is an appropriate choice among the industrial compressors to be used in a 4 MW locomotive SOFC-GT with topping cycle design. The multi-stage radial design of the compressor enhances the ability of the compressor to maintain air flow rate during transient step-load changes. These transient step-load changes are exhibited in many potential applications for SOFC/GT systems. The compressor provides sustained air flow rate during the mild stall/surge event that occurs due to the transient step-load change that is applied, indicating that this type of compressor is well-suited for this hybrid application.

  6. Spurious behavior in volcanic records of geomagnetic field reversals

    NASA Astrophysics Data System (ADS)

    Carlut, Julie; Vella, Jerome; Valet, Jean-Pierre; Soler, Vicente; Legoff, Maxime

    2016-04-01

    Very large directional variations of magnetization have been reported in several lava flows recording a geomagnetic reversal. Such behavior could reflect real geomagnetic changes or be caused by artifacts due to post-emplacement alteration and/or non-ideal magnetic behavior. More recently, a high resolution paleomagnetic record from sediments pleads also for an extremely rapid reversal process during the last reversal. Assuming that the geomagnetic field would have moved by tens of degrees during cooling of moderate thickness lava flows implies brief episodes of rapid changes by a few degrees per day that are difficult to reconcile with the rate of liquid motions at the core surface. Systematical mineralogical bias is a most likely explanation to promote such behavior as recently reconsidered by Coe et al., 2014 for the rapid field changes recorded at Steens Mountain. We resampled three lava flows at La Palma island (Canarias) that are sandwiched between reverse polarity and normal polarity flows associated with the last reversal. The results show an evolution of the magnetization direction from top to bottom. Thermal demagnetization experiments were conducted using different heating and cooling rates. Similarly, continuous demagnetization and measurements. In both cases, we did not notice any remagnetization associated with mineralogical transformations during the experiments. Magnetic grain sizes do not show any correlation with the amplitude of the deviations. Microscopic observations indicate poor exsolution, which could suggests post-cooling thermochemical remagnetization processes.

  7. Geomorphic change caused by outburst floods and debris flows at Mount Rainier, Washington, with emphasis on Tahoma Creek valley

    USGS Publications Warehouse

    Walder, J.S.; Driedger, C.L.

    1994-01-01

    Debris flows have caused rapid geomorphic change in several glacierized drainages on Mount Rainier, Washington. Nearly all of these flows began as glacial outburst floods, then transformed to debris flows by incorporating large masses of sediment in channel reaches where streams have incised proglacial sediments and stagnant glacier ice. This stagnant ice is a relic of advanced glacier positions achieved during the mid-nineteenth century Little Ice Age maximum and the readvance of the 1960's and 1970's. Debris flows have been especially important agents of geomorphic change along Tahoma Creek, which drains South Tahoma Glacier. Debris flows in Tahoma Creek valley have transported downstream about 107 m3 Of sediment since 1967, causing substantial aggradation and damage to roads and facilities in Mount Rainier National Park. The average denudation rate in the upper part of the Tahoma Creek drainage basin in the same period has been extraordinarily high: more than 20 millimeters per year, a value exceeded only rarely in basins affected by debris flows. However, little or none of this sediment has yet passed out of the Tahoma Creek drainage basin. Outburst floods from South Tahoma Glacier form by release of subglacially stored water. The volume of stored water discharged during a typical outburst flood would form a layer several tens of millimeters thick over the bed of the entire glacier, though it is more likely that large linked cavities account for most of the storage. Statistical analysis shows that outburst floods usually occur during periods of atypically hot or rainy weather in summer or early autumn, and that the probability of an outburst increases with temperature (a proxy measure of ablation rate) or rainfall rate. On the basis of these results, we suggest that outburst floods are triggered when rapid input of water to the glacier bed causes transient increase in water pressure, thereby destabilizing the linked-cavity system. The probabilistic nature of the relation between water-input rate and outburst-flood occurrence suggests that the connections between englacial conduits, basal cavities and main meltwater channels may vary temporally. The correlation between outburst floods and meteorological factors casts doubt on an earlier hypothesis that melting around geothermal vents triggers outburst floods from South Tahoma Glacier. The likelihood that outburst floods from South Tahoma Glacier will trigger debris flows should decrease with time, as the deeply incised reach of Tahoma Creek widens by normal slope processes and stagnant ice decays. Drawing analogies to the geomorphic evolution of a reach of Tahoma Creek first incised by an outburst flood in 1967, we suggest the present period of debris-flow activity along Tahoma Creek will last about 25 years, that is, until about the year 2010. Comparison of geomorphic change at Tahoma Creek to that in two other glacierized alphine basins indicates that debris-rich stagnant ice can be an importantsource of sediment to debris flows as long as floods are frequent or channel slope is great.

  8. Comparative evaluation of thermal decomposition behavior and thermal stability of powdered ammonium nitrate under different atmosphere conditions.

    PubMed

    Yang, Man; Chen, Xianfeng; Wang, Yujie; Yuan, Bihe; Niu, Yi; Zhang, Ying; Liao, Ruoyu; Zhang, Zumin

    2017-09-05

    In order to analyze the thermal decomposition characteristics of ammonium nitrate (AN), its thermal behavior and stability under different conditions are studied, including different atmospheres, heating rates and gas flow rates. The evolved decomposition gases of AN in air and nitrogen are analyzed with a quadrupole mass spectrometer. Thermal stability of AN at different heating rates and gas flow rates are studied by differential scanning calorimetry, thermogravimetric analysis, paired comparison method and safety parameter evaluation. Experimental results show that the major evolved decomposition gases in air are H 2 O, NH 3 , N 2 O, NO, NO 2 and HNO 3 , while in nitrogen, H 2 O, NH 3 , NO and HNO 3 are major components. Compared with nitrogen atmosphere, lower initial and end temperatures, higher heat flux and broader reaction temperature range are obtained in air. Meanwhile, higher air gas flow rate tends to achieve lower reaction temperature and to reduce thermal stability of AN. Self-accelerating decomposition temperature of AN in air is much lower than that in nitrogen. It is considered that thermostability of AN is influenced by atmosphere, heating rate and gas flow rate, thus changes of boundary conditions will influence its thermostability, which is helpful to its safe production, storage, transportation and utilization. Copyright © 2017 Elsevier B.V. All rights reserved.

  9. Resistance to blood flow in the rabbit ophthalmic artery after topical treatment with timolol.

    PubMed

    Liu, John H K; Li, Ruixia; Nelson, Thomas R; Weinreb, Robert N

    2007-04-01

    The aim of this study was to investigate the resistance to blood flow in the ophthalmic artery of rabbits receiving topical treatment with timolol. Eight (8) New Zealand albino rabbits received 20 mul of timolol treatment (vehicle, 0.1%, 0.33%, 1%, and 3.3%) on the right eye. Blood-flow velocity in the ophthalmic artery was determined in the treated eye using color Doppler imaging (CDI) with a 12-MHz linear ultrasound transducer prior to the treatment and at 0.5, 1, 1.5, 2, and 3 h after the treatment. Intraocular pressure (IOP) was measured in both eyes, using a pneumatonometer at the same time points. Pourcelot's resistive index of blood flow was calculated, using the peak systolic velocity and the end diastolic velocity. A control experiment was performed with CDI obtained from the right eye when the left eye was treated with 1% timolol. In the eye treated with 1% and 3.3% timolol, a dose-dependent increase in the resistive index of blood flow occurred in the ophthalmic artery. No change in the resistive index occurred when the contralateral eye was treated with 1% timolol. Changes of IOP were not different between the two eyes under all the experimental conditions. Timolol, at all concentrations, caused a significant reduction of heart rate. A similar reduction of heart rate occurred when either eye was treated with 1% timolol. Topical treatment with timolol in rabbits can increase the resistance to blood flow in the ophthalmic artery. This effect is caused by a mechanism local to the eye and is not dependent on an IOP change.

  10. Subsurface Controls on Stream Intermittency in a Semi-Arid Landscape

    NASA Astrophysics Data System (ADS)

    Dohman, J.; Godsey, S.; Thackray, G. D.; Hale, R. L.; Wright, K.; Martinez, D.

    2017-12-01

    Intermittent streams currently constitute 30% to greater than 50% of the global river network. In addition, the number of intermittent streams is expected to increase due to changes in land use and climate. These streams provide important ecosystem services, such as water for irrigation, increased biodiversity, and high rates of nutrient cycling. Many hydrological studies have focused on mapping current intermittent flow regimes or evaluating long-term flow records, but very few have investigated the underlying causes of stream intermittency. The disconnection and reconnection of surface flow reflects the capacity of the subsurface to accommodate flow, so characterizing subsurface flow is key to understanding stream drying. We assess how subsurface flow paths control local surface flows during low-flow periods, including intermittency. Water table dynamics were monitored in an intermittent reach of Gibson Jack Creek in southeastern Idaho. Four transects were delineated with a groundwater well located in the hillslope, riparian zone, and in the stream, for a total of 12 groundwater wells. The presence or absence of surface flow was determined by frequent visual observations as well as in situ loggers every 30m along the 200m study reach. The rate of surface water drying was measured in conjunction with temperature, precipitation, subsurface hydraulic conductivity, hillslope-riparian-stream connectivity and subsurface travel time. Initial results during an unusually wet year suggest different responses in reaches that were previously observed to occasionally cease flowing. Flows in the intermittent reaches had less coherent and lower amplitude diel variations during base flow periods than reaches that had never been observed to dry out. Our findings will help contribute to our understanding of mechanisms driving expansion and contraction cycles in intermittent streams, increase our ability to predict how land use and climate change will affect flow regimes, and improve management of our critical water resources.

  11. Modelling of subarachnoid space width changes in apnoea resulting as a function of blood flow parameters.

    PubMed

    Kalicka, Renata; Mazur, Kamila; Wolf, Jacek; Frydrychowski, Andrzej F; Narkiewicz, Krzysztof; Winklewski, Pawel J

    2017-09-01

    During apnoea, the pial artery is subjected to two opposite physiological processes: vasoconstriction due to elevated blood pressure and vasorelaxation driven by rising pH in the brain parenchyma. We hypothesized that the pial artery response to apnoea may vary, depending on which process dominate. Apnoea experiments were performed in a group of 19 healthy, non-smoking volunteers (9 men and 10 women). The following parameters were obtained for further analysis: blood pressure, the cardiac (from 0.5 to 5.0Hz) and slow (<0.5Hz) components of subarachnoid space width, heart rate, mean cerebral blood flow velocity in the internal carotid artery, pulsatility and resistivity index, internal carotid artery diameter, blood oxygen saturation and end-tidal carbon dioxide. The experiment consisted of three apnoeas, sequentially: 30s, 60s and maximal apnoea. The breath-hold was separated for 5minute rest. The control process is sophisticated, involving internal cross-couplings and cross-dependences. The aim of work was to find a mathematical dependence between data. Unexpectedly, the modelling revealed two different reactions, on the same experimental procedure. As a consequence, there are two subsets of cardiac subarachnoid space width responses to breath-hold in humans. A positive cardiac subarachnoid space width change to apnoea depends on changes in heart rate and cerebral blood flow velocity. A negative cardiac subarachnoid space width change to apnoea is driven by heart rate, mean arterial pressure and pulsatility index changes. The described above two different reactions to experimental breath-hold provides new insights into our understanding of the complex mechanisms governing the adaptation to apnoea in humans. We proposed a mathematical methodology that can be used in further clinical research. Copyright © 2017 Elsevier Inc. All rights reserved.

  12. Monitoring hypoxia induced changes in cochlear blood flow and hemoglobin concentration using a combined dual-wavelength laser speckle contrast imaging and Doppler optical microangiography system.

    PubMed

    Reif, Roberto; Qin, Jia; Shi, Lei; Dziennis, Suzan; Zhi, Zhongwei; Nuttall, Alfred L; Wang, Ruikang K

    2012-01-01

    A synchronized dual-wavelength laser speckle contrast imaging (DWLSCI) system and a Doppler optical microangiography (DOMAG) system was developed to determine several ischemic parameters in the cochlea due to a systemic hypoxic challenge. DWLSCI can obtain two-dimensional data, and was used to determine the relative changes in cochlear blood flow, and change in the concentrations of oxyhemoglobin (HbO), deoxyhemoglobin (Hb) and total hemoglobin (HbT) in mice. DOMAG can obtain three-dimensional data, and was used to determine the changes in cochlear blood flow with single vessel resolution. It was demonstrated that during a hypoxic challenge there was an increase in the concentrations of Hb, a decrease in the concentrations of HbO and cochlear blood flow, and a slight decrease in the concentration of HbT. Also, the rate of change in the concentrations of Hb and HbO was quantified during and after the hypoxic challenge. The ability to simultaneously measure these ischemic parameters with high spatio-temporal resolution will allow the detailed quantitative analysis of several hearing disorders, and will be useful for diagnosing and developing treatments.

  13. Stagnation point flow of wormlike micellar solutions in a microfluidic cross-slot device: effects of surfactant concentration and ionic environment.

    PubMed

    Haward, Simon J; McKinley, Gareth H

    2012-03-01

    We employ the techniques of microparticle image velocimetry and full-field birefringence microscopy combined with mechanical measurements of the pressure drop to perform a detailed characterization of the extensional rheology and elastic flow instabilities observed for a range of wormlike micellar solutions flowing through a microfluidic cross-slot device. As the flow rate through the device is increased, the flow first bifurcates from a steady symmetric to a steady asymmetric configuration characterized by a birefringent strand of highly aligned micellar chains oriented along the shear-free centerline of the flow field. At higher flow rates the flow becomes three dimensional and time dependent and is characterized by aperiodic spatiotemporal fluctuations of the birefringent strand. The extensional properties and critical conditions for the onset of flow instabilities in the fluids are highly dependent on the fluid formulation (surfactant concentration and ionic strength) and the resulting changes in the linear viscoelasticity and nonlinear shear rheology of the fluids. By combining the measurements of critical conditions for the flow transitions with the viscometric material properties and the degree of shear-thinning characterizing each test fluid, it is possible to construct a stability diagram for viscoelastic flow of complex fluids in the cross-slot geometry.

  14. Occupational status and job stress in relation to cardiovascular stress reactivity in Japanese workers.

    PubMed

    Hirokawa, Kumi; Ohira, Tetsuya; Nagayoshi, Mako; Kajiura, Mitsugu; Imano, Hironori; Kitamura, Akihiko; Kiyama, Masahiko; Okada, Takeo; Iso, Hiroyasu

    2016-12-01

    This study aimed to investigate the effects of occupational status and job stress factors on cardiovascular stress reactivity in Japanese workers. In this baseline assessment between 2001 and 2009 in Osaka, Japan, we examined 928 healthy Japanese employees (330 men, 598 women) from two occupational statuses: managers/professionals and general workers. A brief job stress questionnaire was used to evaluate job stress levels. Systolic and diastolic blood pressure (SBP, DBP), heart rate, heart rate variability (high-frequency [HF], low-frequency [LF], LF/HF], and peripheral blood flow were measured at rest and during two stressful tasks. Changes in stress reactivity were calculated as the difference between the measured variables during the tasks and the rest period. Men showed inverse associations between quantitative job overload and DBP, heart rate, and LF/HF, between physical demands and blood pressure (SBP, DBP), and between a poor physical environment and HF. Men also had positive associations between qualitative job overload and heart rate, and between physical demands and peripheral blood flow (all p < 0.05). Women showed inverse associations between qualitative job overload and SBP, and showed positive associations between qualitative job overload and peripheral blood flow, and between a poor physical environment and SBP (all p < 0.05). When stratified by occupational status, significant associations between job stress and changes in stress reactivity were observed in male managers/professionals and female general workers (p < 0.05). Job stress levels are associated with changes in cardiovascular stress reactivity in men and women. Occupational status may modify these associations.

  15. Flow enhances photosynthesis in marine benthic autotrophs by increasing the efflux of oxygen from the organism to the water

    PubMed Central

    Mass, Tali; Genin, Amatzia; Shavit, Uri; Grinstein, Mor; Tchernov, Dan

    2010-01-01

    Worldwide, many marine coastal habitats are facing rapid deterioration due in part to human-driven changes in habitat characteristics, including changes in flow patterns, a factor known to greatly affect primary production in corals, algae, and seagrasses. The effect of flow traditionally is attributed to enhanced influx of nutrients and dissolved inorganic carbon (DIC) across the benthic boundary layer from the water to the organism however, here we report that the organism’s photosynthetic response to changes in the flow is nearly instantaneous, and that neither nutrients nor DIC limits this rapid response. Using microelectrodes, dual-pulse amplitude-modulated fluorometry, particle image velocimetry, and real time mass-spectrometry with the common scleractinian coral Favia veroni, the alga Gracilaria cornea, and the seagrass Halophila stipulacea, we show that this augmented photosynthesis is due to flow-driven enhancement of oxygen efflux from the organism to the water, which increases the affinity of the RuBisCO to CO2. No augmentation of photosynthesis was found in the absence of flow or when flow occurred, but the ambient concentration of oxygen was artificially elevated. We suggest that water motion should be considered a fundamental factor, equivalent to light and nutrients, in determining photosynthesis rates in marine benthic autotrophs. PMID:20133799

  16. Flow enhances photosynthesis in marine benthic autotrophs by increasing the efflux of oxygen from the organism to the water.

    PubMed

    Mass, Tali; Genin, Amatzia; Shavit, Uri; Grinstein, Mor; Tchernov, Dan

    2010-02-09

    Worldwide, many marine coastal habitats are facing rapid deterioration due in part to human-driven changes in habitat characteristics, including changes in flow patterns, a factor known to greatly affect primary production in corals, algae, and seagrasses. The effect of flow traditionally is attributed to enhanced influx of nutrients and dissolved inorganic carbon (DIC) across the benthic boundary layer from the water to the organism however, here we report that the organism's photosynthetic response to changes in the flow is nearly instantaneous, and that neither nutrients nor DIC limits this rapid response. Using microelectrodes, dual-pulse amplitude-modulated fluorometry, particle image velocimetry, and real time mass-spectrometry with the common scleractinian coral Favia veroni, the alga Gracilaria cornea, and the seagrass Halophila stipulacea, we show that this augmented photosynthesis is due to flow-driven enhancement of oxygen efflux from the organism to the water, which increases the affinity of the RuBisCO to CO(2). No augmentation of photosynthesis was found in the absence of flow or when flow occurred, but the ambient concentration of oxygen was artificially elevated. We suggest that water motion should be considered a fundamental factor, equivalent to light and nutrients, in determining photosynthesis rates in marine benthic autotrophs.

  17. A compressible near-wall turbulence model for boundary layer calculations

    NASA Technical Reports Server (NTRS)

    So, R. M. C.; Zhang, H. S.; Lai, Y. G.

    1992-01-01

    A compressible near-wall two-equation model is derived by relaxing the assumption of dynamical field similarity between compressible and incompressible flows. This requires justifications for extending the incompressible models to compressible flows and the formulation of the turbulent kinetic energy equation in a form similar to its incompressible counterpart. As a result, the compressible dissipation function has to be split into a solenoidal part, which is not sensitive to changes of compressibility indicators, and a dilational part, which is directly affected by these changes. This approach isolates terms with explicit dependence on compressibility so that they can be modeled accordingly. An equation that governs the transport of the solenoidal dissipation rate with additional terms that are explicitly dependent on the compressibility effects is derived similarly. A model with an explicit dependence on the turbulent Mach number is proposed for the dilational dissipation rate. Thus formulated, all near-wall incompressible flow models could be expressed in terms of the solenoidal dissipation rate and straight-forwardly extended to compressible flows. Therefore, the incompressible equations are recovered correctly in the limit of constant density. The two-equation model and the assumption of constant turbulent Prandtl number are used to calculate compressible boundary layers on a flat plate with different wall thermal boundary conditions and free-stream Mach numbers. The calculated results, including the near-wall distributions of turbulence statistics and their limiting behavior, are in good agreement with measurements. In particular, the near-wall asymptotic properties are found to be consistent with incompressible behavior; thus suggesting that turbulent flows in the viscous sublayer are not much affected by compressibility effects.

  18. Temperature constraints on the Ginkgo flow of the Columbia River Basalt Group

    NASA Astrophysics Data System (ADS)

    Ho, Anita M.; Cashman, Katharine V.

    1997-05-01

    This study provides the first quantitative estimate of heat loss for a Columbia River Basalt Group flow. A glass composition-based geothermometer was experimentally calibrated for a composition representative of the 500-km-long Ginkgo flow of the Columbia River Basalt Group to measure temperature change during transport. Melting experiments were conducted on a bulk sample at 1 atm between 1200 and 1050 °C. Natural glass was sampled from the margin of a feeder dike near Kahlotus, Washington, and from pillow basalt at distances of 120 km (Vantage, Washington), 350 km (Molalla, Oregon), and 370 km (Portland, Oregon). Ginkgo basalt was also sampled at its distal end at Yaquina Head, Oregon (500 km). Comparison of the glass MgO content, K2O in plagioclase, and measured crystallinities in the experimental charges and natural samples tightly constrains the minimum flow temperature to 1085 ± 5 °C. Glass and plagioclase compositions indicate an upper temperature of 1095 ± 5 °C; thus the maximum temperature decrease along the flow axis of the Ginkgo is 20 °C, suggesting cooling rates of 0.02 0.04 °C/km. These cooling rates, substantially lower than rates observed in active and historic flows, are inconsistent with turbulent flow models. Calculated melt temperatures and viscosities of 240 750 Pa · s allow emplacement either as a fast laminar flow under an insulating crust or as a slower, inflated flow.

  19. Heat conduction in cooling flows. [in clusters of galaxies

    NASA Technical Reports Server (NTRS)

    Bregman, Joel N.; David, L. P.

    1988-01-01

    It has been suggested that electron conduction may significantly reduce the accretion rate (and star foramtion rate) for cooling flows in clusters of galaxies. A numerical hydrodynamics code was used to investigate the time behavior of cooling flows with conduction. The usual conduction coefficient is modified by an efficiency factor, mu, to realize the effects of tangled magnetic field lines. Two classes of models are considered, one where mu is independent of position and time, and one where inflow stretches the field lines and changes mu. In both cases, there is only a narrow range of initial conditions for mu in which the cluster accretion rate is reduced while a significant temperature gradient occurs. In the first case, no steady solution exists in which both conditions are met. In the second case, steady state solutions occur in which both conditions are met, but only for a narrow range of initial values where mu = 0.001.

  20. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yu, Shifeng; Wang, Shuyu; Lu, Ming

    In this paper, vanadium thin films were deposited on sapphire substrates by DC magnetron sputtering and then oxidized in a tube furnace filled with oxygen under different temperatures and oxygen flow rates. The significant influence of the oxygen flow rate and oxidation temperature on the electrical and structural properties of the vanadium oxide thin films were investigated systematically. It shows the pure vanadium dioxide (VO 2) state can only be obtained in a very narrow temperature and oxygen flow rate range. The resistivity change during the metal-insulator transition varies from 0.2 to 4 orders of magnitude depending on the oxidationmore » condition. Large thermal hysteresis during the metal-insulator phase transition was observed during the transition compared to the results in literature. Proper oxidation conditions can significantly reduce the thermal hysteresis. Finally, the fabricated VO 2 thin films showed the potential to be applied in the development of electrical sensors and other smart devices.« less

  1. Experimentally Modeling Black and White Hole Event Horizons via Fluid Flow

    NASA Astrophysics Data System (ADS)

    Manheim, Marc E.; Lindner, John F.; Manz, Niklas

    We will present a scaled down experiment that hydrodynamically models the interaction between electromagnetic waves and black/white holes. It has been mathematically proven that gravity waves in water can behave analogously to electromagnetic waves traveling through spacetime. In this experiment, gravity waves will be generated in a water tank and propagate in a direction opposed to a flow of varying rate. We observe a noticeable change in the wave's spreading behavior as it travels through the simulated horizon with decreased wave speeds up to standing waves, depending on the opposite flow rate. Such an experiment has already been performed in a 97.2 cubic meter tank. We reduced the size significantly to be able to perform the experiment under normal lab conditions.

  2. Accelerated dissolution testing for controlled release microspheres using the flow-through dissolution apparatus.

    PubMed

    Collier, Jarrod W; Thakare, Mohan; Garner, Solomon T; Israel, Bridg'ette; Ahmed, Hisham; Granade, Saundra; Strong, Deborah L; Price, James C; Capomacchia, A C

    2009-01-01

    Theophylline controlled release capsules (THEO-24 CR) were used as a model system to evaluate accelerated dissolution tests for process and quality control and formulation development of controlled release formulations. Dissolution test acceleration was provided by increasing temperature, pH, flow rate, or adding surfactant. Electron microscope studies on the theophylline microspheres subsequent to each experiment showed that at pH values of 6.6 and 7.6 the microspheres remained intact, but at pH 8.6 they showed deterioration. As temperature was increased from 37-57 degrees C, no change in microsphere integrity was noted. Increased flow rate also showed no detrimental effect on integrity. The effect of increased temperature was determined to be the statistically significant variable.

  3. A precipitation-runoff model for the analysis of the effects of water withdrawals and land-use change on streamflow in the Usquepaug-Queen River Basin, Rhode Island

    USGS Publications Warehouse

    Zarriello, Phillip J.; Bent, Gardner C.

    2004-01-01

    The 36.1-square-mile UsquepaugQueen River Basin in south-central Rhode Island is an important water resource. Streamflow records indicate that withdrawals may have diminished flows enough to affect aquatic habitat. Concern over the effect of withdrawals on streamflow and aquatic habitat prompted the development of a Hydrologic Simulation ProgramFORTRAN (HSPF) model to evaluate the water-management alternatives and land-use change in the basin. Climate, streamflow, and water-use data were collected to support the model development. A logistic-regression equation was developed for long-term simulations to predict the likelihood of irrigation, the primary water use in the basin, from antecedent potential evapotranspiration and precipitation for generating irrigation demands. The HSPF model represented the basin by 13 pervious-area and 2 impervious-area land-use segments and 20 stream reaches. The model was calibrated to the period January 1, 2000 to September 30, 2001, at three continuous streamflow-gaging stations that monitor flow from 10, 54, and 100 percent of the basin drainage area. Hydrographs and flow-duration curves of observed and simulated discharges, along with statistics compiled for various model-fit metrics, indicate a satisfactory model performance. The calibrated HSPF model was modified to evaluate streamflow (1) under no withdrawals to streamflow under current (200001) withdrawal conditions under long-term (19602001) climatic conditions, (2) under withdrawals by the former Ladd School water-supply wells, and (3) under fully developed land use. The effects of converting from direct-stream withdrawals to ground-water withdrawals were evaluated outside of the HSPF model by use of the STRMDEPL program, which calculates the time delayed response of ground-water withdrawals on streamflow depletion. Simulated effects of current withdrawals relative to no withdrawals indicate about a 20-percent decrease in the lowest mean daily streamflows at the basin outlet, but withdrawals have little effect on flows that are exceeded less than about 90 percent of the time. Tests of alternative model structures to evaluate model uncertainty indicate that the lowest mean daily flows ranged between 3 and 5 cubic feet per second (ft3/s) without withdrawals and 2.2 to 4 ft3/s with withdrawals. Changes in the minimum daily streamflows are more pronounced, however; at the upstream streamflow-gaging station, a minimum daily flow of 0.2 ft3/s was sustained without withdrawals, but simulations with withdrawals indicate that the reach would stop flowing part of a day about 5 percent of the time. The effect on streamflow of potential ground-water withdrawals of 0.20, 0.90, and 1.78 million gallons per day (Mgal/d) at the former Ladd School near the central part of the basin were evaluated. The lowest daily mean flows in model reach 3, the main stem of the Queen River closest to the pumped wells, decreased by about 50 percent for withdrawals of 0.20 Mgal/d (from about 0.4 to 0.2 ft3/s) in comparison to current withdrawals. Reach 3 would occasionally stop flowing during part of the day at the 0.20-Mgal/d withdrawal rate because of diurnal fluctuation in streamflow. The higher withdrawal rates (0.90 and 1.78 Mgal/d) would cause reach 3 to stop flowing about 10 to 20 percent of the time, but the effects of pumping rapidly diminished downstream because of tributary inflows. Simulation results indicate little change in the annual 1-, 7-, and 30-day low flows at the 0.20 Mgal/d pumping rate, but at the 1.78 Mgal/d pumping rate, reach 3 stopped flowing for nearly a 7-day period every year and for a 30-day period about every other year. At the 0.90 Mgal/d pumping rate, reach 3 stopped flowing about every other year for a 7-day period and about once every 5 years for a 30-day period. Land-use change was simulated by converting model hydrologic-response units (HRUs) representing undeveloped areas to HRUs representing developed areas o

  4. Spontaneous electric current flow during deformation of non-piezoelectric marble samples: an indicator of stress state?

    NASA Astrophysics Data System (ADS)

    Cartwright-Taylor, A. L.; Sammonds, P. R.; Vallianatos, F.

    2016-12-01

    We recorded spontaneous electric current flow in non-piezoelectric Carrara marble samples during triaxial deformation. Mechanical data, ultrasonic velocities and acoustic emissions were acquired simultaneously with electric current to constrain the relationship between electric current flow, differential stress and damage. Under strain-controlled loading, spontaneous electric current signals (nA) were generated and sustained under all conditions tested. In dry samples, a detectable electric current arises only during dilatancy and is correlated with the damage induced by microcracking. Signal variations with confining pressure correspond to microcrack suppression, while variations with strain rate are associated with time-dependent differences in deformation mechanism across the brittle to semi-brittle transition. In the brittle regime, the signal exhibits a precursory change as damage localises and the stress drop accelerates towards failure. This change is particularly distinct at dynamic strain rates. Similar changes are seen in the semi-brittle regime although the signal is more oscillatory in nature. Current flow in dry samples is proportional to stress within 90% of peak stress. In fluid-saturated samples proportionality holds from 40% peak stress, with a significant increase in the rate of current production from 90% peak stress associated with fluid flow during dilatancy. This direct relationship demonstrates that electric current could be used as a proxy for stress, indicating when the rock is reaching the limit of its strength. The experimental power law relationship between electric current and strain rate, which mirrors the power-law creep equation, supports this observation. High-frequency fluctuations of electric current are not normally distributed - they exhibit `heavy-tails'. We model these distributions with q-Gaussian statistics and evolution of the q-parameter during deformation reveals a two-stage precursory anomaly prior to sample failure, consistent with the acoustic emissions b-value and stress intensity evolution as modelled from fracture mechanics. Our findings support the idea that electric currents in the crust can be generated purely from solid state fracture processes and that these currents may reflect the stress state within the damaged rock.

  5. Using the VentCam and Optical Plume Velocimetry to Measure High-Temperature Hydrothermal Fluid Flow Rates in the ASHES Vent Field on Axial Volcano

    NASA Astrophysics Data System (ADS)

    Crone, T. J.; Mittelstaedt, E. L.; Fornari, D. J.

    2014-12-01

    Fluid flow rates through high-temperature mid-ocean ridge hydrothermal vents are likely quite sensitive to poroelastic forcing mechanisms such as tidal loading and tectonic activity. Because poroelastic deformation and flow perturbations are estimated to extend to considerable depths within young oceanic crust, observations of flow rate changes at seafloor vents have the potential to provide constraints on the flow geometry and permeability structure of the underlying hydrothermal systems, as well as the quantities of heat and chemicals they exchange with overlying ocean, and the potential biological productivity of ecosystems they host. To help provide flow rate measurements in these challenging environments, we have developed two new optical flow oriented technologies. The first is a new form of Optical Plume Velocimetry (OPV) which relies on single-frame temporal cross-correlation to obtain time-averaged image velocity fields from short video sequences. The second is the VentCam, a deep sea camera system that can collect high-frame-rate video sequences at focused hydrothermal vents suitable for analysis with OPV. During the July 2014 R/V Atlantis/Alvin expedition to Axial Seamount, we deployed the VentCam at the ~300C Phoenix vent within the ASHES vent field and positioned it with DSRV Alvin. We collected 24 seconds of video at 50 frames per second every half-hour for approximately 10 days beginning July 22nd. We are currently applying single-frame lag OPV to these videos to estimate relative and absolute fluid flow rates through this vent. To explore the relationship between focused and diffuse venting, we deployed a second optical flow camera, the Diffuse Effluent Measurement System (DEMS), adjacent to this vent at a fracture within the lava carapace where low-T (~30C) fluids were exiting. This system collected video sequences and diffuse flow measurements at overlapping time intervals. Here we present the preliminary results of our work with VentCam and OPV, and comparisons with results from the DEMS camera.

  6. Direct Measurement of Xylem Pressure in Leaves of Intact Maize Plants. A Test of the Cohesion-Tension Theory Taking Hydraulic Architecture into Consideration1

    PubMed Central

    Wei, Chunfang; Tyree, Melvin T.; Steudle, Ernst

    1999-01-01

    The water relations of maize (Zea mays L. cv Helix) were documented in terms of hydraulic architecture and xylem pressure. A high-pressure flowmeter was used to characterize the hydraulic resistances of the root, stalk, and leaves. Xylem pressure measurements were made with a Scholander-Hammel pressure bomb and with a cell pressure probe. Evaporation rates were measured by gas exchange and by gravimetric measurements. Xylem pressure was altered by changing the light intensity, by controlling irrigation, or by gas pressure applied to the soil mass (using a root pressure bomb). Xylem pressure measured by the cell pressure probe and by the pressure bomb agreed over the entire measured range of 0 to −0.7 MPa. Experiments were consistent with the cohesion-tension theory. Xylem pressure changed rapidly and reversibly with changes in light intensity and root-bomb pressure. Increasing the root-bomb pressure increased the evaporation rate slightly when xylem pressure was negative and increased water flow rate through the shoots dramatically when xylem pressure was positive and guttation was observed. The hydraulic architecture model could predict all observed changes in water flow rate and xylem. We measured the cavitation threshold for oil- and water-filled pressure probes and provide some suggestions for improvement. PMID:10594106

  7. Effects of forcing time scale on the simulated turbulent flows and turbulent collision statistics of inertial particles

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rosa, B., E-mail: bogdan.rosa@imgw.pl; Parishani, H.; Department of Earth System Science, University of California, Irvine, California 92697-3100

    2015-01-15

    In this paper, we study systematically the effects of forcing time scale in the large-scale stochastic forcing scheme of Eswaran and Pope [“An examination of forcing in direct numerical simulations of turbulence,” Comput. Fluids 16, 257 (1988)] on the simulated flow structures and statistics of forced turbulence. Using direct numerical simulations, we find that the forcing time scale affects the flow dissipation rate and flow Reynolds number. Other flow statistics can be predicted using the altered flow dissipation rate and flow Reynolds number, except when the forcing time scale is made unrealistically large to yield a Taylor microscale flow Reynoldsmore » number of 30 and less. We then study the effects of forcing time scale on the kinematic collision statistics of inertial particles. We show that the radial distribution function and the radial relative velocity may depend on the forcing time scale when it becomes comparable to the eddy turnover time. This dependence, however, can be largely explained in terms of altered flow Reynolds number and the changing range of flow length scales present in the turbulent flow. We argue that removing this dependence is important when studying the Reynolds number dependence of the turbulent collision statistics. The results are also compared to those based on a deterministic forcing scheme to better understand the role of large-scale forcing, relative to that of the small-scale turbulence, on turbulent collision of inertial particles. To further elucidate the correlation between the altered flow structures and dynamics of inertial particles, a conditional analysis has been performed, showing that the regions of higher collision rate of inertial particles are well correlated with the regions of lower vorticity. Regions of higher concentration of pairs at contact are found to be highly correlated with the region of high energy dissipation rate.« less

  8. Effects of flow-path variations on internal reversing flow in a tailpipe offtake configuration for ASTOVL aircraft

    NASA Technical Reports Server (NTRS)

    Mcardle, Jack G.; Esker, Barbara S.

    1993-01-01

    A one-third-scale model of a generic tailpipe offtake system for an advanced short takeoff, vertical landing (ASTOVL) aircraft was tested at the NASA Lewis Research Center Powered Lift Facility. The basic model consisted of a tailpipe with a center body to form an annulus simulating turbine outflow with no swirl; twin offtake ducts with elbows at the ends to turn the flow to a downward direction; flow control nozzles at the ends of the elbows; and a blind flange at the end of the tailpipe to simulate a closed cruise nozzle. The offtake duct-to-tailpipe diameter ratio was 0.74. Modifications of a generic nature were then made to this basic configuration to measure the effects of flow-path changes on the flow and pressure-loss characteristics. The modifications included adding rounded entrances at the forward edges of the offtake openings, blocking the tailpipe just aft the openings instead of at the cruise nozzle, changing the location of the openings along the tailpipe, removing the center body, and varying the Mach number (flow rate) over a wide range in the tailpipe ahead of the openings by changing the size of the flow control nozzles. The tests were made with unheated air at tailpipe-to-ambient pressure ratios from 1.4 to 5. Results are presented and compared with performance graphs, total-pressure contour plots, paint streak flow visualization photographs, and a flow-angle probe traverse at the offtake entrance.

  9. Calculation of gas turbine characteristic

    NASA Astrophysics Data System (ADS)

    Mamaev, B. I.; Murashko, V. L.

    2016-04-01

    The reasons and regularities of vapor flow and turbine parameter variation depending on the total pressure drop rate π* and rotor rotation frequency n are studied, as exemplified by a two-stage compressor turbine of a power-generating gas turbine installation. The turbine characteristic is calculated in a wide range of mode parameters using the method in which analytical dependences provide high accuracy for the calculated flow output angle and different types of gas dynamic losses are determined with account of the influence of blade row geometry, blade surface roughness, angles, compressibility, Reynolds number, and flow turbulence. The method provides satisfactory agreement of results of calculation and turbine testing. In the design mode, the operation conditions for the blade rows are favorable, the flow output velocities are close to the optimal ones, the angles of incidence are small, and the flow "choking" modes (with respect to consumption) in the rows are absent. High performance and a nearly axial flow behind the turbine are obtained. Reduction of the rotor rotation frequency and variation of the pressure drop change the flow parameters, the parameters of the stages and the turbine, as well as the form of the characteristic. In particular, for decreased n, nonmonotonic variation of the second stage reactivity with increasing π* is observed. It is demonstrated that the turbine characteristic is mainly determined by the influence of the angles of incidence and the velocity at the output of the rows on the losses and the flow output angle. The account of the growing flow output angle due to the positive angle of incidence for decreased rotation frequencies results in a considerable change of the characteristic: poorer performance, redistribution of the pressure drop at the stages, and change of reactivities, growth of the turbine capacity, and change of the angle and flow velocity behind the turbine.

  10. Climate-induced seasonal changes in smallmouth bass growth rate potential at the southern range extent

    USGS Publications Warehouse

    Middaugh, Christopher R.; Kessinger, Brin; Magoulick, Daniel D.

    2018-01-01

    Temperature increases due to climate change over the coming century will likely affect smallmouth bass (Micropterus dolomieu) growth in lotic systems at the southern extent of their native range. However, the thermal response of a stream to warming climate conditions could be affected by the flow regime of each stream, mitigating the effects on smallmouth bass populations. We developed bioenergetics models to compare change in smallmouth bass growth rate potential (GRP) from present to future projected monthly stream temperatures across two flow regimes: runoff and groundwater-dominated. Seasonal differences in GRP between stream types were then compared. The models were developed for fourteen streams within the Ozark–Ouachita Interior Highlands in Arkansas, Oklahoma and Missouri, USA, which contain smallmouth bass. In our simulations, smallmouth bass mean GRP during summer months decreased by 0.005 g g−1 day−1 in runoff streams and 0.002 g g−1 day−1 in groundwater streams by the end of century. Mean GRP during winter, fall and early spring increased under future climate conditions within both stream types (e.g., 0.00019 g g−1 day−1 in runoff and 0.0014 g g−1 day−1 in groundwater streams in spring months). We found significant differences in change in GRP between runoff and groundwater streams in three seasons in end-of-century simulations (spring, summer and fall). Potential differences in stream temperature across flow regimes could be an important habitat component to consider when investigating effects of climate change as fishes from various flow regimes that are relatively close geographically could be affected differently by warming climate conditions.

  11. Correlations between topography and intraflow width behavior in Martian and terrestrial lava flows

    NASA Astrophysics Data System (ADS)

    Peitersen, Matthew N.; Crown, David A.

    2000-02-01

    Local correlations between topography and width behavior within lava flows at Puu Oo, Mount Etna, Glass Mountain, Cerro Bayo, Alba Patera, Tyrrhena Patera, Elysium Mons, and Olympus Mons were investigated. For each flow, width and slope data were both referenced via downflow distance as a sequence of points; the data were then divided into collections of adjacent three-point features and two-point segments. Four discrete types of analyses were conducted: (1) Three-point analysis examined positional correlations between width and slope features, (2) two-point analysis did the same for flow segments, (3) mean slope analysis included segment slope comparisons, and (4) sudden width behavior analysis measured abruptness of width changes. The distribution of types of correlations compared to random combinations of features and segments does not suggest a significant correlation between flow widths and local underlying slopes and indicates that for these flows at least, other factors have more influence on changes in width than changes in underlying topography. Mean slopes underlying narrowing, widening, and constant flow width segments were calculated. An inverse correlation between slope and width was found only at Mount Etna, where slopes underlying narrowing segments were greater than those underlying widening in 62% of the examined flows. For the majority of flows at Mount Etna, Puu Oo, and Olympus Mons, slopes were actually greatest under constant width segments; this may imply a topographically dependent resistance to width changes. The rate of change of width was also examined. Sudden width changes are relatively common at Puu Oo, Mount Etna, Elysium Mons, and Tyrrhena Patera and relatively rare at Glass Mountain, Cerro Bayo, Olympus Mons, and Alba Patera. After correction for mapping scale, Puu Oo, Mount Etna, Olympus Mons, and Alba Patera appear to fall on the same trend; Glass Mount exhibits unusually small amounts of sudden width behavior, and Tyrrhena Patera exhibits a relatively large number of sudden width behavior occurrences.

  12. A study of the action of amlodipine on adrenergically regulated sodium handling by the kidney in normotensive and hypertensive rats.

    PubMed Central

    Johns, E. J.

    1988-01-01

    1. An investigation was undertaken to examine the effect of calcium channel blockade, induced by amlodipine, on the ability of the renal sympathetic nerves to cause an antidiuresis and anti-natriuresis in normotensive Sprague Dawley and spontaneously hypertensive rats anaesthetized with pentobarbitone. 2. Low frequency renal nerve stimulation in normotensive rats, which did not change renal blood flow, caused a 15% reduction in glomerular filtration rate and was associated with falls in urine flow of 37%, absolute sodium excretion of 47%, and fractional sodium excretion of 38%. The magnitude of these renal excretory changes was unaffected by prior administration of amlodipine at either 200 micrograms kg-1 plus 50 micrograms kg-1 h-1 or 400 micrograms kg-1 plus 100 micrograms kg-1 h-1. Amlodipine given in the higher dose, decreased basal levels of blood pressure and increased basal urine flow and sodium excretion. 3. In spontaneously hypertensive rats, renal nerve stimulation minimally affected renal haemodynamics but decreased urine flow, absolute and fractional sodium excretion by 29%, 31% and 24%, respectively. 4. Similar renal nerve stimulation in spontaneously hypertensive rats given amlodipine at 200 micrograms kg-1 plus 50 micrograms kg-1 h-1 or 400 micrograms kg-1 plus 100 micrograms kg-1 h-1 caused minimal changes in renal haemodynamics and in the excretion of water and sodium. The higher dose of drug resulted in decreased blood pressure and increased basal rates of urine flow and sodium excretion.(ABSTRACT TRUNCATED AT 250 WORDS) PMID:2967097

  13. Computational modeling of epithelial fluid and ion transport in the parotid duct after transfection of human aquaporin-1

    PubMed Central

    Chiorini, John A; Sneyd, James; Suresh, Vinod

    2017-01-01

    Previous studies have shown that localized delivery of the aquaporin-1 (AQP1) gene to the parotid duct can restore saliva flow in minipigs following irradiation-induced salivary hypofunction. The resulting flow rate and electrochemistry of secreted saliva contradicts current understanding of ductal fluid transport. We hypothesized that changes in expression of ion transport proteins have occurred following AQP1 transfection. We use a mathematical model of ion and fluid transport across the parotid duct epithelial cells to predict the expression profile of ion transporters that are consistent with the experimental measurements of saliva composition and secretion rates. Using a baseline set of parameters, the model reproduces the data for the irradiated, non-AQP1-transfected case. We propose three scenarios which may have occurred after transfection, which differ in the location of the AQP1 gene. The first scenario places AQP1 within nonsecretory cells, and requires that epithelial sodium channel (ENaC) expression is greatly reduced (1.3% of baseline), and ductal bicarbonate concentration is increased from 40.6 to 137.0 mM, to drive water secretion into the duct. The second scenario introduces the AQP1 gene into all ductal cells. The final scenario has AQP1 primarily in the proximal duct cells which secrete water under baseline conditions. We find the change in the remaining cells includes a 95.8% reduction in ENaC expression, enabling us to reproduce all experimental ionic concentrations within 9 mM. These findings provide a mechanistic basis for the observations and will guide the further development of gene transfer therapy for salivary hypofunction. NEW & NOTEWORTHY Following transfection of aquaporin into the parotid ducts of minipigs with salivary hypofunction, the resulting increase in salivary flow rates contradicts current understanding of ductal fluid transport. We show that the change in saliva electrochemistry and flow rate can be explained by changes in expression of ion transporters in the ductal cell membranes, using a mathematical model replicating a single parotid duct. PMID:27932503

  14. Computational modeling of epithelial fluid and ion transport in the parotid duct after transfection of human aquaporin-1.

    PubMed

    Fong, Shelley; Chiorini, John A; Sneyd, James; Suresh, Vinod

    2017-02-01

    Previous studies have shown that localized delivery of the aquaporin-1 (AQP1) gene to the parotid duct can restore saliva flow in minipigs following irradiation-induced salivary hypofunction. The resulting flow rate and electrochemistry of secreted saliva contradicts current understanding of ductal fluid transport. We hypothesized that changes in expression of ion transport proteins have occurred following AQP1 transfection. We use a mathematical model of ion and fluid transport across the parotid duct epithelial cells to predict the expression profile of ion transporters that are consistent with the experimental measurements of saliva composition and secretion rates. Using a baseline set of parameters, the model reproduces the data for the irradiated, non-AQP1-transfected case. We propose three scenarios which may have occurred after transfection, which differ in the location of the AQP1 gene. The first scenario places AQP1 within nonsecretory cells, and requires that epithelial sodium channel (ENaC) expression is greatly reduced (1.3% of baseline), and ductal bicarbonate concentration is increased from 40.6 to 137.0 mM, to drive water secretion into the duct. The second scenario introduces the AQP1 gene into all ductal cells. The final scenario has AQP1 primarily in the proximal duct cells which secrete water under baseline conditions. We find the change in the remaining cells includes a 95.8% reduction in ENaC expression, enabling us to reproduce all experimental ionic concentrations within 9 mM. These findings provide a mechanistic basis for the observations and will guide the further development of gene transfer therapy for salivary hypofunction. Following transfection of aquaporin into the parotid ducts of minipigs with salivary hypofunction, the resulting increase in salivary flow rates contradicts current understanding of ductal fluid transport. We show that the change in saliva electrochemistry and flow rate can be explained by changes in expression of ion transporters in the ductal cell membranes, using a mathematical model replicating a single parotid duct. Copyright © 2017 the American Physiological Society.

  15. A multi-scale GIS and hydrodynamic modelling approach to fish passage assessment: Clarence and Shoalhaven Rivers, NSW Australia

    NASA Astrophysics Data System (ADS)

    Bonetti, Rita M.; Reinfelds, Ivars V.; Butler, Gavin L.; Walsh, Chris T.; Broderick, Tony J.; Chisholm, Laurie A.

    2016-05-01

    Natural barriers such as waterfalls, cascades, rapids and riffles limit the dispersal and in-stream range of migratory fish, yet little is known of the interplay between these gradient dependent landforms, their hydraulic characteristics and flow rates that facilitate fish passage. The resurgence of dam construction in numerous river basins world-wide provides impetus to the development of robust techniques for assessment of the effects of downstream flow regime changes on natural fish passage barriers and associated consequences as to the length of rivers available to migratory species. This paper outlines a multi-scale technique for quantifying the relative magnitude of natural fish passage barriers in river systems and flow rates that facilitate passage by fish. First, a GIS-based approach is used to quantify channel gradients for the length of river or reach under investigation from a high resolution DEM, setting the magnitude of identified passage barriers in a longer context (tens to hundreds of km). Second, LiDAR, topographic and bathymetric survey-based hydrodynamic modelling is used to assess flow rates that can be regarded as facilitating passage across specific barriers identified by the river to reach scale gradient analysis. Examples of multi-scale approaches to fish passage assessment for flood-flow and low-flow passage issues are provided from the Clarence and Shoalhaven Rivers, NSW, Australia. In these river systems, passive acoustic telemetry data on actual movements and migrations by Australian bass (Macquaria novemaculeata) provide a means of validating modelled assessments of flow rates associated with successful fish passage across natural barriers. Analysis of actual fish movements across passage barriers in these river systems indicates that two dimensional hydraulic modelling can usefully quantify flow rates associated with the facilitation of fish passage across natural barriers by a majority of individual fishes for use in management decisions regarding environmental or instream flows.

  16. Effect of filter media size, mass flow rate and filtration stage number in a moving-bed granular filter on the yield and properties of bio-oil from fast pyrolysis of biomass.

    PubMed

    Paenpong, Chaturong; Inthidech, Sudsakorn; Pattiya, Adisak

    2013-07-01

    Fast pyrolysis of cassava rhizome was performed in a bench-scale fluidised-bed reactor unit incorporated with a cross-flow moving-bed granular filter. The objective of this research was to examine several process parameters including the granular size (425-1160 μm) and mass flow rate (0-12 g/min) as well as the number of the filtration stages (1-2 stages) on yields and properties of bio-oil. The results showed that the bio-oil yield decreased from 57.7 wt.% to 42.0-49.2 wt.% when increasing the filter media size, the mass flow rate and the filtration stage number. The effect of the process parameters on various properties of bio-oil is thoroughly discussed. In general, the bio-oil quality in terms of the solids content, ash content, initial viscosity, viscosity change and ageing rate could be enhanced by the hot vapour granular filtration. Therefore, bio-oil of high stability could be produced by the pyrolysis reactor configuration designed in this work. Copyright © 2013 Elsevier Ltd. All rights reserved.

  17. Damping Rates of Energetic Particle Modes and Stability With Changing Equilibrium Conditions in the MST Reversed-Field Pinch

    NASA Astrophysics Data System (ADS)

    Sears, S. H.; Almagri, A. F.; Anderson, J. K.; Bonofiglo, P. J.; Capecchi, W.; Kim, J.

    2016-10-01

    The damping of Alfvenic waves is an important process, with implications varying from anomalous ion heating in laboratory and astrophysical plasmas to the stability of fusion alpha-driven modes in a burning plasma. With a 1 MW NBI on the MST, a controllable set of energetic particle modes (EPMs) and Alfvenic eigenmodes can be excited. We investigate the damping of these modes as a function of both magnetic and flow shear. Typical EPM damping rates are -104 s-1 in standard RFP discharges. Magnetic shear in the region of large energetic ion density is -2 cm-1 and can be increased up to -2.5 cm-1 by varying the boundary field. Continuum mode damping rates can be reduced up to 50%. New experiments use a bias probe to control the rotation profile. Accelerating the edge plasma relative to the rapidly rotating NBI-driven core decreases the flow shear, while decelerating the edge plasma increases the flow shear in the region of strong energetic ion population. Mode damping rates measured as a function of the local flow shear are compared to ideal MHD predictions. Work supported by US DOE.

  18. Cooling and crystallization of lava in open channels, and the transition of Pāhoehoe Lava to 'A'ā

    NASA Astrophysics Data System (ADS)

    Cashman, Katharine V.; Thornber, Carl; Kauahikaua, James P.

    Samples collected from a lava channel active at Kīlauea Volcano during May 1997 are used to constrain rates of lava cooling and crystallization during early stages of flow. Lava erupted at near-liquidus temperatures ( 1150 °C) cooled and crystallized rapidly in upper parts of the channel. Glass geothermometry indicates cooling by 12-14 °C over the first 2km of transport. At flow velocities of 1-2m/s, this translates to cooling rates of 22-50 °C/h. Cooling rates this high can be explained by radiative cooling of a well-stirred flow, consistent with observations of non-steady flow in proximal regions of the channel. Crystallization of plagioclase and pyroxene microlites occurred in response to cooling, with crystallization rates of 20-50% per hour. Crystallization proceeded primarily by nucleation of new crystals, and nucleation rates of 104/cm3s are similar to those measured in the 1984 open channel flow from Mauna Loa Volcano. There is no evidence for the large nucleation delays commonly assumed for plagioclase crystallization in basaltic melts, possibly a reflection of enhanced nucleation due to stirring of the flow. The transition of the flow surface morphology from pāhoehoe to 'a'ā occurred at a distance of 1.9km from the vent. At this point, the flow was thermally stratified, with an interior temperature of 1137 °C and crystallinity of 15%, and a flow surface temperature of 1100 °C and crystallinity of 45%. 'A'ā formation initiated along channel margins, where crust was continuously disrupted, and involved tearing and clotting of the flow surface. Both observations suggest that the transition involved crossing of a rheological threshold. We suggest this threshold to be the development of a lava yield strength sufficient to prevent viscous flow of lava at the channel margin. We use this concept to propose that 'a'ā formation in open channels requires both sufficiently high strain rates for continued disruption of surface crusts and sufficient groundmass crystallinity to generate a yield strength equivalent to the imposed stress. In Hawai'i, where lava is typically microlite poor on eruption, these combined requirements help to explain two common observations on 'a'ā formation: (a) 'a'ā flow fields are generated when effusion rates are high (thus promoting crustal disruption); and (b) under most eruption conditions, lava issues from the vent as pāhoehoe and changes to 'a'ā only after flowing some distance, thus permitting sufficient crystallization.

  19. Physiological Signal Analysis for Evaluating Flow during Playing of Computer Games of Varying Difficulty.

    PubMed

    Tian, Yu; Bian, Yulong; Han, Piguo; Wang, Peng; Gao, Fengqiang; Chen, Yingmin

    2017-01-01

    Flow is the experience of effortless attention, reduced self-consciousness, and a deep sense of control that typically occurs during the optimal performance of challenging tasks. On the basis of the person-artifact-task model, we selected computer games (tasks) with varying levels of difficulty (difficult, medium, and easy) and shyness (personality) as flow precursors to study the physiological activity of users in a flow state. Cardiac and respiratory activity and mean changes in skin conductance (SC) were measured continuously while the participants ( n = 40) played the games. Moreover, the associations between self-reported psychological flow and physiological measures were investigated through a series of repeated-measures analyses. The results showed that the flow experience is related to a faster respiratory rate, deeper respiration, moderate heart rate (HR), moderate HR variability, and moderate SC. The main effect of shyness was non-significant, whereas the interaction of shyness and difficulty influenced the flow experience. These findings are discussed in relation to current models of arousal and valence. The results indicate that the flow state is a state of moderate mental effort that arises through the increased parasympathetic modulation of sympathetic activity.

  20. Physiological Signal Analysis for Evaluating Flow during Playing of Computer Games of Varying Difficulty

    PubMed Central

    Tian, Yu; Bian, Yulong; Han, Piguo; Wang, Peng; Gao, Fengqiang; Chen, Yingmin

    2017-01-01

    Flow is the experience of effortless attention, reduced self-consciousness, and a deep sense of control that typically occurs during the optimal performance of challenging tasks. On the basis of the person–artifact–task model, we selected computer games (tasks) with varying levels of difficulty (difficult, medium, and easy) and shyness (personality) as flow precursors to study the physiological activity of users in a flow state. Cardiac and respiratory activity and mean changes in skin conductance (SC) were measured continuously while the participants (n = 40) played the games. Moreover, the associations between self-reported psychological flow and physiological measures were investigated through a series of repeated-measures analyses. The results showed that the flow experience is related to a faster respiratory rate, deeper respiration, moderate heart rate (HR), moderate HR variability, and moderate SC. The main effect of shyness was non-significant, whereas the interaction of shyness and difficulty influenced the flow experience. These findings are discussed in relation to current models of arousal and valence. The results indicate that the flow state is a state of moderate mental effort that arises through the increased parasympathetic modulation of sympathetic activity. PMID:28725206

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