What are the underlying units of perceived animacy? Chasing detection is intrinsically object-based.

PubMed

van Buren, Benjamin; Gao, Tao; Scholl, Brian J

2017-10-01

One of the most foundational questions that can be asked about any visual process is the nature of the underlying 'units' over which it operates (e.g., features, objects, or spatial regions). Here we address this question-for the first time, to our knowledge-in the context of the perception of animacy. Even simple geometric shapes appear animate when they move in certain ways. Do such percepts arise whenever any visual feature moves appropriately, or do they require that the relevant features first be individuated as discrete objects? Observers viewed displays in which one disc (the "wolf") chased another (the "sheep") among several moving distractor discs. Critically, two pairs of discs were also connected by visible lines. In the Unconnected condition, both lines connected pairs of distractors; but in the Connected condition, one connected the wolf to a distractor, and the other connected the sheep to a different distractor. Observers in the Connected condition were much less likely to describe such displays using mental state terms. Furthermore, signal detection analyses were used to explore the objective ability to discriminate chasing displays from inanimate control displays in which the wolf moved toward the sheep's mirror-image. Chasing detection was severely impaired on Connected trials: observers could readily detect an object chasing another object, but not a line-end chasing another line-end, a line-end chasing an object, or an object chasing a line-end. We conclude that the underlying units of perceived animacy are discrete visual objects.

Discovering highly obscured AGN with the Swift-BAT 100-month survey

NASA Astrophysics Data System (ADS)

Marchesi, Stefano; Ajello, Marco; Comastri, Andrea; Cusumano, Giancarlo; La Parola, Valentina; Segreto, Alberto

2017-01-01

In this talk, I present a new technique to find highly obscured AGN using the 100-month Swift-BAT survey. I will show the results of the combined Chandra and BAT spectral analysis in the 0.3-150 keV band of seven Seyfert 2 galaxies selected from the 100-month BAT catalog. We selected nearby (z<0.03) sources lacking of a ROSAT counterpart and never previously observed in the 0.3-10 keV energy range. All the objects are significantly obscured, having NH>1E23 cm-2 at a >99% confidence level, and one to three sources are candidate Compton thick Active Galactic Nuclei (CT-AGN), i.e., have NH>1E24 cm-2.Since the selection criteria we adopted have been extremely effective in detecting highly obscured AGN, further observations of these and other Seyfert 2 galaxies selected from the BAT 100-month catalog will allow us to create a statistically significant sample of highly obscured AGN, therefore better understanding the physics of the obscuration processes.

Paper Chase and the Socratic Method of Teaching Law.

ERIC Educational Resources Information Center

Dillon, J. T.

1980-01-01

It is argued that the Socratic method of teaching law as depicted in the book, movie, and TV series "Paper Chase" is not really the Socratic method at all. The genuine Socratic method and the questioning technique used in "Paper Chase" are examined and their appropriateness and effectiveness as methods for teaching contract law…

A Vicious Cycle: A Cross-Sectional Study of Canine Tail-Chasing and Human Responses to It, Using a Free Video-Sharing Website

PubMed Central

Burn, Charlotte C.

2011-01-01

Tail-chasing is widely celebrated as normal canine behaviour in cultural references. However, all previous scientific studies of tail-chasing or ‘spinning’ have comprised small clinical populations of dogs with neurological, compulsive or other pathological conditions; most were ultimately euthanased. Thus, there is great disparity between scientific and public information on tail-chasing. I gathered data on the first large (n = 400), non-clinical tail-chasing population, made possible through a vast, free, online video repository, YouTube™. The demographics of this online population are described and discussed. Approximately one third of tail-chasing dogs showed clinical signs, including habitual (daily or ‘all the time’) or perseverative (difficult to distract) performance of the behaviour. These signs were observed across diverse breeds. Clinical signs appeared virtually unrecognised by the video owners and commenting viewers; laughter was recorded in 55% of videos, encouragement in 43%, and the commonest viewer descriptors were that the behaviour was ‘funny’ (46%) or ‘cute’ (42%). Habitual tail-chasers had 6.5+/−2.3 times the odds of being described as ‘Stupid’ than other dogs, and perseverative dogs were 6.8+/−2.1 times more frequently described as ‘Funny’ than distractible ones were. Compared with breed- and age-matched control videos, tail-chasing videos were significantly more often indoors and with a computer/television screen switched on. These findings highlight that tail-chasing is sometimes pathological, but can remain untreated, or even be encouraged, because of an assumption that it is ‘normal’ dog behaviour. The enormous viewing figures that YouTube™ attracts (mean+/−s.e. = 863+/−197 viewings per tail-chasing video) suggest that this perception will be further reinforced, without effective intervention. PMID:22096487

High levels of absorption in orientation-unbiased, radio-selected 3CR Active Galaxies

NASA Astrophysics Data System (ADS)

Wilkes, Belinda J.; Haas, Martin; Barthel, Peter; Leipski, Christian; Kuraszkiewicz, Joanna; Worrall, Diana; Birkinshaw, Mark; Willner, Steven P.

2014-08-01

A critical problem in understanding active galaxies (AGN) is the separation of intrinsic physical differences from observed differences that are due to orientation. Obscuration of the active nucleus is anisotropic and strongly frequency dependent leading to complex selection effects for observations in most wavebands. These can only be quantified using a sample that is sufficiently unbiased to test orientation effects. Low-frequency radio emission is one way to select a close-to orientation-unbiased sample, albeit limited to the minority of AGN with strong radio emission.Recent Chandra, Spitzer and Herschel observations combined with multi-wavelength data for a complete sample of high-redshift (1 24.2) = 2.5:1.4:1 in these high-luminosity (log L(0.3-8keV) ~ 44-46) sources. These ratios are consistent with current expectations based on modelingthe Cosmic X-ray Background. A strong correlation with radio orientation constrains the geometry of the obscuring disk/torus to have a ~60 degree opening angle and ~12 degree Compton-thick cross-section. The deduced ~50% obscured fraction of the population contrasts with typical estimates of ~20% obscured in optically- and X-ray-selected high-luminosity samples. Once the primary nuclear emission is obscured, AGN X-ray spectra are frequently dominated by unobscured non-nuclear or scattered nuclear emission which cannot be distinguished from direct nuclear emission with a lower obscuration level unless high quality data is available. As a result, both the level of obscuration and the estimated instrinsic luminosities of highly-obscured AGN are likely to be significantly (*10-1000) underestimated for 25-50% of the population. This may explain the lower obscured fractions reported for optical and X-ray samples which have no independent measure of the AGN luminosity. Correcting AGN samples for these underestimated luminosities would result in flatter derived luminosity functions and potentially change their evolution.

78 FR 69663 - Jonathan and Jayne Chase Troy Mills Hydroelectric Inc.; Notice of Transfer of Exemption

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-20

... Jayne Chase Troy Mills Hydroelectric Inc.; Notice of Transfer of Exemption 1. By letter filed October 15, 2013, Jonathan Chase informed the Commission that the exemption from licensing for the Troy Hydroelectric Project, FERC No. 13381, originally issued December 2, 2011,\\1\\ has been transferred to Troy Mills...

Effect of body temperature on chondroitinase ABC's ability to cleave chondroitin sulfate glycosaminoglycans.

PubMed

Tester, Nicole J; Plaas, Anna H; Howland, Dena R

2007-04-01

Chondroitinase ABC (Ch'ase ABC) is a bacterial lyase that degrades chondroitin sulfate (CS), dermatan sulfate, and hyaluronan glycosaminoglycans (GAGs). This enzyme has received significant attention as a potential therapy for promoting central nervous system and peripheral nervous system repair based on its degradation of CS GAGs. Determination of the stability of Ch'ase ABC activity at temperatures equivalent to normal (37 degrees C) and elevated (39 degrees C) body temperatures is important for optimizing its clinical usage. We report here data obtained from examining enzymatic activity at these temperatures across nine lots of commercially available protease-free Ch'ase ABC. CS GAG degrading activity was assayed by using 1) immunohistochemical detection of unsaturated disaccharide stubs generated by digestion of proteoglycans in tissue sections and 2) fluorophore-assisted carbohydrate electrophoresis (FACE) and/or high-performance liquid chromatography (HPLC) to separate and quantify unsaturated disaccharide digestion products. Our results indicate that there is a significant effect of lot and time on enzymatic thermostability. Average enzymatic activity is significantly decreased at 1 and 3 days at 39 degrees C and 37 degrees C, respectively. Furthermore, the average activity seen after 1 day was significantly different between the two temperatures. Addition of bovine serum albumin as a stabilizer significantly preserved enzymatic activity at 1 day, but not 3 days, at 39 degrees C. These results show that the CS GAG degrading activity of Ch'ase ABC is significantly decreased with incubation at body temperature over time and that all lots do not show equal thermostability. These findings are important for the design and interpretation of experimental and potential clinical studies involving Ch'ase ABC. (c) 2007 Wiley-Liss, Inc.

The Constant Average Relationship Between Dust-obscured Star Formation and Stellar Mass from z=0 to z=2.5

NASA Astrophysics Data System (ADS)

Whitaker, Katherine E.; Pope, Alexandra; Cybulski, Ryan; Casey, Caitlin M.; Popping, Gergo; Yun, Min; 3D-HST Collaboration

2018-01-01

The total star formation budget of galaxies consists of the sum of the unobscured star formation, as observed in the rest-frame ultraviolet (UV), together with the obscured component that is absorbed and re-radiated by dust grains in the infrared. We explore how the fraction of obscured star formation depends (SFR) and stellar mass for mass-complete samples of galaxies at 0 < z < 2.5. We combine GALEX and WISE photometry for SDSS-selected galaxies with the 3D-HST treasury program and Spitzer/MIPS 24μm photometry in the well-studied 5 extragalactic CANDELS fields. We find a strong dependence of the fraction of obscured star formation (f_obscured=SFR_IR/SFR_UV+IR) on stellar mass, with remarkably little evolution in this fraction with redshift out to z=2.5. 50% of star formation is obscured for galaxies with log(M/M⊙)=9.4 although unobscured star formation dominates the budget at lower masses, there exists a tail of low mass extremely obscured star-forming galaxies at z > 1. For log(M/M⊙)>10.5, >90% of star formation is obscured at all redshifts. We also show that at fixed total SFR, f_obscured is lower at higher redshift. At fixed mass, high-redshift galaxies are observed to have more compact sizes and much higher star formation rates, gas fractions and hence surface densities (implying higher dust obscuration), yet we observe no redshift evolution in f_obscured with stellar mass. This poses a challenge to theoretical models to reproduce, where the observed compact sizes at high redshift seem in tension with lower dust obscuration.

The Constant Average Relationship between Dust-obscured Star Formation and Stellar Mass from z = 0 to z = 2.5

NASA Astrophysics Data System (ADS)

Whitaker, Katherine E.; Pope, Alexandra; Cybulski, Ryan; Casey, Caitlin M.; Popping, Gergö; Yun, Min S.

2017-12-01

The total star formation budget of galaxies consists of the sum of the unobscured star formation, as observed in the rest-frame ultraviolet (UV), together with the obscured component that is absorbed and re-radiated by dust grains in the infrared. We explore how the fraction of obscured star formation depends on stellar mass for mass-complete samples of galaxies at 0< z< 2.5. We combine GALEX and WISE photometry for SDSS-selected galaxies with the 3D-HST treasury program and Spitzer/MIPS 24 μm photometry in the well-studied five extragalactic Cosmic Assembly Near-IR Deep Extragalactic Legacy Survey (CANDELS) fields. We find a strong dependence of the fraction of obscured star formation (f obscured = SFRIR/SFRUV+IR) on stellar mass, with remarkably little evolution in this fraction with redshift out to z = 2.5. 50% of star formation is obscured for galaxies with log(M/M ⊙) = 9.4 although unobscured star formation dominates the budget at lower masses, there exists a tail of low-mass, extremely obscured star-forming galaxies at z> 1. For log(M/M ⊙) > 10.5, >90% of star formation is obscured at all redshifts. We also show that at fixed total SFR, {f}{obscured} is lower at higher redshift. At fixed mass, high-redshift galaxies are observed to have more compact sizes and much higher star formation rates, gas fractions, and hence surface densities (implying higher dust obscuration), yet we observe no redshift evolution in {f}{obscured} with stellar mass. This poses a challenge to theoretical models, where the observed compact sizes at high redshift seem in tension with lower dust obscuration.

Neural correlates of effective learning in experienced medical decision-makers.

PubMed

Downar, Jonathan; Bhatt, Meghana; Montague, P Read

2011-01-01

Accurate associative learning is often hindered by confirmation bias and success-chasing, which together can conspire to produce or solidify false beliefs in the decision-maker. We performed functional magnetic resonance imaging in 35 experienced physicians, while they learned to choose between two treatments in a series of virtual patient encounters. We estimated a learning model for each subject based on their observed behavior and this model divided clearly into high performers and low performers. The high performers showed small, but equal learning rates for both successes (positive outcomes) and failures (no response to the drug). In contrast, low performers showed very large and asymmetric learning rates, learning significantly more from successes than failures; a tendency that led to sub-optimal treatment choices. Consistently with these behavioral findings, high performers showed larger, more sustained BOLD responses to failed vs. successful outcomes in the dorsolateral prefrontal cortex and inferior parietal lobule while low performers displayed the opposite response profile. Furthermore, participants' learning asymmetry correlated with anticipatory activation in the nucleus accumbens at trial onset, well before outcome presentation. Subjects with anticipatory activation in the nucleus accumbens showed more success-chasing during learning. These results suggest that high performers' brains achieve better outcomes by attending to informative failures during training, rather than chasing the reward value of successes. The differential brain activations between high and low performers could potentially be developed into biomarkers to identify efficient learners on novel decision tasks, in medical or other contexts.

The identification of N-linked oligosaccharides on the human CR2/Epstein-Barr virus receptor and their function in receptor metabolism, plasma membrane expression, and ligand binding.

PubMed

Weis, J J; Fearon, D T

1985-11-05

Human complement receptor type 2 (CR2) was biosynthetically labeled by pulsing SB B lymphoblastoid cells for 25 min with [35S]methionine followed by chase in the presence of excess unlabeled methionine. An Mr 134,000 polypeptide represented the major form of the receptor at the end of the pulse period, and within 1 h of chase this disappeared coincident with the appearance of the Mr 145,000 mature form of CR2. Precursor, but not mature, CR2 was sensitive to endoglycosidase H, indicating that maturation of CR2 represented processing of N-linked high mannose oligosaccharides to the complex type. The processing of precursor CR2 was impaired by monensin. In the presence of tunicamycin an Mr 111,000 form of CR2 was synthesized by SB cells, and this did not chase into either precursor or mature CR2. This Mr 111,000 form of CR2 did not incorporate [3H]glucosamine, indicating that it lacked both N- and O-linked oligosaccharide. The half-lives of mature CR2 and nonglycosylated CR2 pulse-labeled in the presence of tunicamycin were 13.8 and 2.8 h, respectively; the turnover rate of B1, a membrane protein normally lacking carbohydrate, was unaffected by the presence of the antibiotic. The percentage of pulse-labeled, nonglycosylated CR2 that was expressed at the cell surface after 1 h of chase in the presence of tunicamycin was 30%, identical to that of mature CR2 in cells chased in the absence of the antibiotic. However, after 6 h of chase there was no additional net accumulation of nonglycosylated CR2 at the plasma membrane, while the proportion of pulse-labeled mature CR2 at this site had risen to 81%. Therefore, N-linked oligosaccharides are essential for the stability of CR2 and have some role in its plasma membrane expression. In contrast, the observation that all three forms of CR2 bound to Sepharose C3 indicates that oligosaccharides are not necessary for the interaction between CR2 and its complement ligand.

Pro-inflammatory adjuvant properties of pigment-grade titanium dioxide particles are augmented by a genotype that potentiates interleukin 1β processing.

PubMed

Riedle, Sebastian; Pele, Laetitia C; Otter, Don E; Hewitt, Rachel E; Singh, Harjinder; Roy, Nicole C; Powell, Jonathan J

2017-12-08

Pigment-grade titanium dioxide (TiO 2 ) particles are an additive to some foods (E171 on ingredients lists), toothpastes, and pharma-/nutraceuticals and are absorbed, to some extent, in the human intestinal tract. TiO 2 can act as a modest adjuvant in the secretion of the pro-inflammatory cytokine interleukin 1β (IL-1β) when triggered by common intestinal bacterial fragments, such as lipopolysaccharide (LPS) and/or peptidoglycan. Given the variance in human genotypes, which includes variance in genes related to IL-1β secretion, we investigated whether TiO 2 particles might, in fact, be more potent pro-inflammatory adjuvants in cells that are genetically susceptible to IL-1β-related inflammation. We studied bone marrow-derived macrophages from mice with a mutation in the nucleotide-binding oligomerisation domain-containing 2 gene (Nod2 m/m ), which exhibit heightened secretion of IL-1β in response to the peptidoglycan fragment muramyl dipeptide (MDP). To ensure relevance to human exposure, TiO 2 was food-grade anatase (119 ± 45 nm mean diameter ± standard deviation). We used a short 'pulse and chase' format: pulsing with LPS and chasing with TiO 2 +/- MDP or peptidoglycan. IL-1β secretion was not stimulated in LPS-pulsed bone marrow-derived macrophages, or by chasing with MDP, and only very modestly so by chasing with peptidoglycan. In all cases, however, IL-1β secretion was augmented by chasing with TiO 2 in a dose-dependent fashion (5-100 μg/mL). When co-administered with MDP or peptidoglycan, IL-1β secretion was further enhanced for the Nod2 m/m genotype. Tumour necrosis factor α was triggered by LPS priming, and more so for the Nod2 m/m genotype. This was enhanced by chasing with TiO 2 , MDP, or peptidoglycan, but there was no additive effect between the bacterial fragments and TiO 2 . Here, the doses of TiO 2 that augmented bacterial fragment-induced IL-1β secretion were relatively high. In vivo, however, selected intestinal cells appear to be loaded with TiO 2 , so such high concentrations may be 'exposure-relevant' for localised regions of the intestine where both TiO 2 and bacterial fragment uptake occurs. Moreover, this effect is enhanced in cells from Nod2 m/m mice indicating that genotype can dictate inflammatory signalling in response to (nano)particle exposure. In vivo studies are now merited.

Attributing intentions to random motion engages the posterior superior temporal sulcus.

PubMed

Lee, Su Mei; Gao, Tao; McCarthy, Gregory

2014-01-01

The right posterior superior temporal sulcus (pSTS) is a neural region involved in assessing the goals and intentions underlying the motion of social agents. Recent research has identified visual cues, such as chasing, that trigger animacy detection and intention attribution. When readily available in a visual display, these cues reliably activate the pSTS. Here, using functional magnetic resonance imaging, we examined if attributing intentions to random motion would likewise engage the pSTS. Participants viewed displays of four moving circles and were instructed to search for chasing or mirror-correlated motion. On chasing trials, one circle chased another circle, invoking the percept of an intentional agent; while on correlated motion trials, one circle's motion was mirror reflected by another. On the remaining trials, all circles moved randomly. As expected, pSTS activation was greater when participants searched for chasing vs correlated motion when these cues were present in the displays. Of critical importance, pSTS activation was also greater when participants searched for chasing compared to mirror-correlated motion when the displays in both search conditions were statistically identical random motion. We conclude that pSTS activity associated with intention attribution can be invoked by top-down processes in the absence of reliable visual cues for intentionality.

Geology and hydrogeology of Naval Air Station Chase Field and Naval Auxiliary Landing Field Goliad, Bee and Goliad counties, Texas

USGS Publications Warehouse

Snyder, G.L.

1995-01-01

Large vertical hydraulic-head gradients are present between the unconfined Evangeline aquifer and confined Fleming aquifers at Naval Air Station Chase Field and Naval Auxiliary Landing Field Goliad. These gradients, together with the results of the aquifer test at Naval Air Station Chase Field and assumed characteristics of the confining units, indicate that downward flow of ground water probably occurs from the water-table aquifer to the underlying aquifers. The rate of downward flow between the two confined Fleming aquifers (from A-sand to B-sand) can be approximated using an estimate of vertical hydraulic conductivity of the intervening confining unit obtained from assumed storage characteristics and data from the aquifer test. Under the relatively high vertical hydraulic-head gradient induced by the aquifer test, ground-water movement from the A-sand aquifer to the B-sand aquifer could require about 490 years; and about 730 years under the natural gradient. Future increases in ground-water withdrawals from the B-sand aquifer might increase downward flow in the aquifer system of the study area.

Gaze maintenance and autism spectrum disorder.

PubMed

Kaye, Leah; Kurtz, Marie; Tierney, Cheryl; Soni, Ajay; Augustyn, Marilyn

2014-01-01

Chase is a 5½-year-old boy whom you have followed in your primary care practice since age 26 months. He was born full-term vaginal delivery weighing 6 pounds 15 ounces. His biological mother used heroin, tobacco, and cocaine during pregnancy. From 8 weeks to 18 months, he spent time in a foster home where he was provided limited attention and nurturing. At age 18 months, he entered a loving foster home; at 26 months, he was adopted. There is maternal history of attention-deficit hyperactivity disorder, learning disability, depression, bipolar disorder, and substance abuse but no history of autism or cognitive disability. Chase received early intervention before adoption. Specific concerns are unknown. At the time of his adoption, he had delays in gross motor and fine motor skills, nonverbal communication, and speech production. Familiar listeners find Chase to be 100% intelligible but unfamiliar listeners understand about 70% of what Chase says. He enjoys being with his adopted mother and imitating her. He has demonstrated significant anxiety during his play therapy. He has difficulty in paying attention to multistep directions. Chase can point and wave but has difficulty following someone's eyes to see where another person is looking. Chase enjoys a variety of interests but has a special fixation on Toy Story characters. Chase does initiate social interactions but can be aggressive toward his siblings and oppositional toward his parents. He is not aggressive at school. Teachers note hyperactivity and impulsivity. Chase is bothered by bright lights and by others making loud noises but has no difficulty with crowds. Chase is reported to have difficulty in transitioning between activities. At his 5-year-old visit, you as well as his mother and therapists note that he has trouble following with his eyes so he is referred to a neuro-ophthalmologist. Evaluation showed Chase was able to fix on and follow objects and light, his peripheral vision was normal, his pupils were equal and reactive without afferent pupillary defect, and normal visual tracking as assessed through pursuit and saccades. There were some head jerking motions observed which were not thought to be part of Chase's attempts to view objects. Gaze impersistence was noted, although it was not clear if this was due to a lack of attention or a true inability to maintain a gaze in the direction instructed. On review of the school's speech and language report, they state that he is >90% intelligible. He has occasional lip trills. Testing with the Clinical Evaluation of Language Fundamentals shows mild delays in receptive language, especially those that require visual attention. Verbal Motor Production Assessment for Children reveals focal oromotor control and sequencing skills that are below average, with groping when asked to imitate single oromotor nonspeech movements and sequenced double oromotor nonspeech movements. At 5½ years, he returns for follow-up, and he is outgoing and imaginative, eager to play and socialize. He makes eye contact but does not always maintain it. He asks and responds to questions appropriately, and he is able to follow verbal directions and verbal redirection. He is very interested in Toy Story characters but willing to share them and plays with other toys. Chase's speech has predictable, easy to decode sound substitutions. On interview with him, you feel that he has borderline cognitive abilities. He also demonstrates good eye contact but lack of visual gaze maintenance; this is the opposite of the pattern you are accustomed to in patients with autism spectrum disorder. What do you do next?

Retention Kinetics of the 18F-Labeled Sympathetic Nerve PET Tracer LMI1195: Comparison with 11C-Hydroxyephedrine and 123I-MIBG.

PubMed

Werner, Rudolf A; Rischpler, Christoph; Onthank, David; Lapa, Constantin; Robinson, Simon; Samnick, Samuel; Javadi, Mehrbod; Schwaiger, Markus; Nekolla, Stephan G; Higuchi, Takahiro

2015-09-01

(18)F-N-[3-bromo-4-(3-fluoro-propoxy)-benzyl]-guanidine ((18)F-LMI1195) is a new PET tracer designed for noninvasive assessment of sympathetic innervation of the heart. The (18)F label facilitates the imaging advantages of PET over SPECT technology while allowing centralized manufacturing. Highly specific neural uptake of (18)F-LMI1195 has previously been established, but the retention kinetics are not yet fully understood. Healthy New Zealand White rabbits were studied with (18)F-LMI1195 using a small-animal PET system. Dynamic 40-min chest scans were started just before intravenous bolus injection of (18)F-LMI1195. Imaging was performed under norepinephrine transport inhibition with desipramine pretreatment, a 1.5 mg/kg desipramine chase administered 10 min after tracer injection, and saline treatment of controls. As a reference, cardiac uptake of (11)C-hydroxyephedrine and (123)I-metaiodobenzylguanidine ((123)I-MIBG) was examined by PET and planar scintigraphy, respectively. Cardiac uptake of all 3 tracers was inhibited by pretreatment with desipramine. Stable cardiac tracer retention was delineated by dynamic PET in control rabbits for (11)C-hydroxyephedrine (washout rate, 0.42% ± 0.57%/min) and (18)F-LMI1195 (washout rate, 0.058% ± 0.28%/min). A desipramine chase increased (11)C-hydroxyephedrine washout from the heart (2.43% ± 0.15%/min, P < 0.001), whereas (18)F-LMI1195 washout was not influenced (0.059% ± 0.11%/min, not statistically significant). Additionally, a desipramine chase did not change the cardiac (123)I-MIBG uptake (delayed heart-to-mediastinum ratio, 1.99 ± 0.12 (desipramine chase) vs. 2.05 ± 0.16 (controls), not statistically significant). In vivo norepinephrine transporter (NET) blockade with desipramine confirmed specific neural uptake of (18)F-LMI1195, (11)C-hydroxyephedrine, and (123)I-MIBG in rabbit hearts. (11)C-hydroxyephedrine cardiac retention was sensitive to a NET inhibitor chase, indicating a cycle of continuous NET uptake and release at the nerve terminals. In contrast, (18)F-LMI1195 and (123)I-MIBG demonstrated stable storage at the nerve terminal with resistance to a NET inhibitor chase, mimicking physiologic norepinephrine turnover. © 2015 by the Society of Nuclear Medicine and Molecular Imaging, Inc.

Additive opportunistic capture explains group hunting benefits in African wild dogs.

PubMed

Hubel, Tatjana Y; Myatt, Julia P; Jordan, Neil R; Dewhirst, Oliver P; McNutt, J Weldon; Wilson, Alan M

2016-03-29

African wild dogs (Lycaon pictus) are described as highly collaborative endurance pursuit hunters based on observations derived primarily from the grass plains of East Africa. However, the remaining population of this endangered species mainly occupies mixed woodland savannah where hunting strategies appear to differ from those previously described. We used high-resolution GPS and inertial technology to record fine-scale movement of all members of a single pack of six adult African wild dogs in northern Botswana. The dogs used multiple short-distance hunting attempts with a low individual kill rate (15.5%), but high group feeding rate due to the sharing of prey. Use of high-level cooperative chase strategies (coordination and collaboration) was not recorded. In the mixed woodland habitats typical of their current range, simultaneous, opportunistic, short-distance chasing by dogs pursuing multiple prey (rather than long collaborative pursuits of single prey by multiple individuals) could be the key to their relative success in these habitats.

Additive opportunistic capture explains group hunting benefits in African wild dogs

PubMed Central

Hubel, Tatjana Y.; Myatt, Julia P.; Jordan, Neil R.; Dewhirst, Oliver P.; McNutt, J. Weldon; Wilson, Alan M.

2016-01-01

African wild dogs (Lycaon pictus) are described as highly collaborative endurance pursuit hunters based on observations derived primarily from the grass plains of East Africa. However, the remaining population of this endangered species mainly occupies mixed woodland savannah where hunting strategies appear to differ from those previously described. We used high-resolution GPS and inertial technology to record fine-scale movement of all members of a single pack of six adult African wild dogs in northern Botswana. The dogs used multiple short-distance hunting attempts with a low individual kill rate (15.5%), but high group feeding rate due to the sharing of prey. Use of high-level cooperative chase strategies (coordination and collaboration) was not recorded. In the mixed woodland habitats typical of their current range, simultaneous, opportunistic, short-distance chasing by dogs pursuing multiple prey (rather than long collaborative pursuits of single prey by multiple individuals) could be the key to their relative success in these habitats. PMID:27023355

The CHASE laboratory search for chameleon dark energy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Steffen, Jason H.; /Fermilab

2010-11-01

A scalar field is a favorite candidate for the particle responsible for dark energy. However, few theoretical means exist that can simultaneously explain the observed acceleration of the Universe and evade tests of gravity. The chameleon mechanism, whereby the properties of a particle depend upon the local environment, is one possible avenue. We present the results of the Chameleon Afterglow Search (CHASE) experiment, a laboratory probe for chameleon dark energy. CHASE marks a significant improvement other searches for chameleons both in terms of its sensitivity to the photon/chameleon coupling as well as its sensitivity to the classes of chameleon darkmore » energy models and standard power-law models. Since chameleon dark energy is virtually indistinguishable from a cosmological constant, CHASE tests dark energy models in a manner not accessible to astronomical surveys.« less

Bobcat attack on a cottontail rabbit

USGS Publications Warehouse

Biggins, D.E.; Biggins, D.M.

2006-01-01

We observed an attack by a bobcat (Lynx rufus) on a cottontail rabbit (Sylvilagus) that involved stealthy approach by the cat for >1 h, followed by a 12.3-s chase covering 116.0 m for the cat and 128.4 m for the rabbit. During the chase, the route of the cat from starting point to kill site was more direct than the semi-circular route of the rabbit. Stride lengths for the cat and total distance covered by the chase were longer than those previously reported for bobcats.

Galaxy gas as obscurer - II. Separating the galaxy-scale and nuclear obscurers of active galactic nuclei

NASA Astrophysics Data System (ADS)

Buchner, Johannes; Bauer, Franz E.

2017-03-01

The 'torus' obscurer of active galactic nuclei (AGN) is poorly understood in terms of its density, sub-structure and physical mechanisms. Large X-ray surveys provide model boundary constraints, for both Compton-thin and Compton-thick levels of obscuration, as obscured fractions are mean covering factors fcov. However, a major remaining uncertainty is host-galaxy obscuration. In Paper I, we discovered a relation of {NH} ∝ M_{star }^{1/3} for the obscuration of galaxy-scale gas. Here, we apply this observational relation to the AGN population, and find that galaxy-scale gas is responsible for a luminosity-independent fraction of Compton-thin AGN, but does not produce Compton-thick columns. With the host-galaxy obscuration understood, we present a model of the remaining nuclear obscurer, which is consistent with a range of observations. Our radiation-lifted torus model consists of a Compton-thick component (fcov ∼ 35 per cent) and a Compton-thin component (fcov ∼ 40 per cent), which depends on both black hole mass and luminosity. This provides a useful summary of observational constraints for torus modellers who attempt to reproduce this behaviour. It can also be employed as a sub-grid recipe in cosmological simulations that do not resolve the torus. We also investigate host-galaxy X-ray obscuration inside cosmological, hydrodynamic simulations (Evolution and Assembly of Galaxies and their Environment; Illustris). The obscuration from ray-traced galaxy gas can agree with observations, but is highly sensitive to the chosen feedback assumptions.

78 FR 42777 - Formations of, Acquisitions by, and Mergers of Bank Holding Companies

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-17

... President) 100 North 6th Street, Philadelphia, Pennsylvania 19105-1521: 1. Fox Chase Bancorp Inc., Hatboro, Pennsylvania; to become a bank holding company upon the conversion of Fox Chase Bank, Hatboro, Pennsylvania...

T-34C back seat instrument panel

NASA Image and Video Library

1997-05-15

The back seat instrument panel on the NASA T-34C chase plane. In its role as a military trainer, the instructor pilot would ride in the back seat, while the student would be in the front seat. As a chase plane, the back seat would be occupied by a photographer. The aircraft was previously used at the Lewis Research Center in propulsion experiments involving turboprop engines, and was used as a chase aircraft at Dryden for smaller and slower research projects. Chase aircraft accompany research flights for photography and video purposes, and also as support for safety and research. At Dryden, the T-34 is used mainly for smaller remotely piloted vehicles which fly slower than NASA's F-18's, used for larger scale projects. This aircraft was returned to the U.S. Navy in May of 2002. The T-34C, built by Beech, carries a crew of 2 and is nicknamed the Mentor.

Stepped leaders observed in ground operations of ADELE

NASA Astrophysics Data System (ADS)

Smith, D. M.; Kelley, N.; Lowell, A.; Martinez-McKinney, F.; Dwyer, J. R.; Splitt, M. E.; Lazarus, S. M.; Cramer, E. S.; Levine, S.; Cummer, S. A.; Lu, G.; Shao, X.; Ho, C.; Eastvedt, E. M.; Trueblood, J.; Edens, H. E.; Hunyady, S. J.; Winn, W. P.; Rassoul, H. K.

2010-12-01

While the Airborne Detector for Energetic Lightning Emissions (ADELE) was designed primarily to study high-energy radiation associated with thunderstorms at aircraft altitude, it can also be used as a mobile ground-based instrument when mounted in a van. ADELE contains scintillation detectors optimized for faint and bright events and a flat-plate antenna measuring dE/dt. In July and August 2010, ADELE was brought to Langmuir Laboratory in New Mexico as a stationary detector and to the Florida peninsula (based at the Florida Institute of Technology in Melbourne) for rapid-response (storm-chasing) operations. In ten days of chasing, stepped-leader x-ray emission was observed from at least four close CG flashes, a much higher rate of success than can be achieved from a stationary detector or array. We will present these four events as well as the results of a study of candidate events of lesser statistical significance. We will also discuss the optimization of lightning-chasing strategies, science goals for future ground campaigns, and what additional instrumentation would be most scientifically beneficial. In the latter category, a proximity sensor (comparing flash and thunder arrival times) and a field mill are particularly important.

Tornado Chasing.

ERIC Educational Resources Information Center

Faidley, Warren

1991-01-01

Presents the rationale and purposes behind the phenomenon known as storm chasing, as well as the contributions that tornado chasers have made to both scientific knowledge and public safety. Provides statistical information on tornado frequencies and locations and contact addresses for storm chasers. (JJK)

Financial stress, attitudes toward money, and scores on a Dream Inventory.

PubMed

Kroth, Jerry; Mann, Sonia; Cervantes, Carolina; Jaffe, Matthew; Ristic, Vera

2010-08-01

During stock market losses in 2009 and high unemployment, ratings on the KJP Dream Inventory were correlated with factors of the Money Attitude Scale and items on the Contemporary Financial Stress Inventory for 71 graduate students in Counseling Psychology and Education. Correlations were significant for Retention on the Money Attitude Scale with Dissociative Avoidance (-.31), Dreams of falling (.26), Risk-taking in dreams (.24), and Dreaming of being chased (.28). Also, ratings for the Money Attitude Scale of Distrust correlated with Discontentedness in dreams (.33) and Dreams of being chased (.26), Repetitive trauma (.33), Nightmares (.30), and Recurring nightmares (.35). Concern about retention in graduate school due to finances correlated with recalled frequencies of nightmares (.27) and dreams of flying (.25).

76 FR 24912 - Sunshine Act Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-03

... DEPARTMENT OF JUSTICE Parole Commission Sunshine Act Meeting TIME AND DATE: 11 a.m., Tuesday, May 10, 2011. PLACE: U.S. Parole Commission, 5550 Friendship Boulevard, Chevy Chase, Maryland. STATUS... the Chairman, U.S. Parole Commission, 5550 Friendship Boulevard, Chevy Chase, Maryland 20815, (301...

Validity of chase car data used in developing emissions cycles

DOT National Transportation Integrated Search

2000-09-01

Air quality policies, driving cycles and profiles of average driving behavior have been constructed to characterize the driving behavior of the overall fleet in an effort to ensure vehicle compliance. Chase car data and speed-time profiles of in-use ...

Social object play among young Japanese macaques (Macaca fuscata) in Arashiyama, Japan.

PubMed

Shimada, Masaki

2006-10-01

Social object play (SOP), i.e., social play using portable object(s), among young Japanese macaques (Macaca fuscata; 0-4 years old) in the Arashiyama E troop was studied using a modified sequence sampling method from July to October 2000. SOP was a relatively common activity for most of the young macaques and often continued for long periods. Participants used many kinds of object, including edible natural objects and artificial objects, such as plastic bottles, but they never used provisioned food or wild fruit in SOP bouts. An analysis of long bouts (>/=0.5 min) revealed the following interactive SOP features: (1) at any given time, participants used only one object, and only one participant held the object; (2) during SOP play-chasing, the object holder was likely to be chased by others; (3) during long bouts, the object changed hands frequently; and (4) agonistic competition for an object among young macaques was rare. Combinations of sexes, ages, relative ranks, or matrilines of the object holder and non-holder did not affect the tendency that the holder was chased by non-holder(s) during play-chasing. Even when there was a change in object holders, the repetitiveness of this interactive pattern, i.e., that the holder would be chased during SOP bouts, distinguished the SOP structure from that of other types of social play without object(s). General proximate social play mechanisms, such as self-handicapping or role taking, were associated with SOP. Other mechanisms that affected SOP included the following: (1) young macaques treated an object as a target in play competition, and (2) 'being the holder of a target object' was associated with the 'role of the chasee.'

6. CONSTRUCTION PROGRESS VIEW (EXTERIOR) OF TANK, CABLE CHASE, AND ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

6. CONSTRUCTION PROGRESS VIEW (EXTERIOR) OF TANK, CABLE CHASE, AND MOUNDED BUNKER. CONSTRUCTION WAS 99 PERCENT COMPLETE. CAMERA IS FACING WEST. INEL PHOTO NUMBER 65-5435, TAKEN OCTOBER 20, 1965. - Idaho National Engineering Laboratory, Advanced Reentry Vehicle Fusing System, Scoville, Butte County, ID

A compilation of chase work characterizes this image, looking south, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

A compilation of chase work characterizes this image, looking south, in the niche which slightly separates E Building form R Building, on the north side - Department of Energy, Mound Facility, Electronics Laboratory Building (E Building), One Mound Road, Miamisburg, Montgomery County, OH

NRC, SPI, and chasing arrows: Is there common ground

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rabasca, L.

After negotiating for 15 months, issuing three white papers, and conducting consumer research, the National Recycling Coalition (NRC, Washington, DC) and the Society of the Plastics Industry, Inc. (SPI, Washington, DC), have agreed to disagree on the use of the familiar chasing arrows logo in SPI's seven-number resin identification code. The desired end result of the talks and debates was supposed to be a plan to change legislation requiring 39 states to use SPI's current resin identification code and a commitment to remove the old code from durable goods and flexible packaging. Ultimately, these actions could have improved markets formore » polyethylene terephthalate (PET) and high-density polyethylene (HDPE) by reducing contamination caused by confusion over what is actually recycled versus what is merely recyclable.« less

The most luminous heavily obscured quasars have a high merger fraction: morphological study of wise -selected hot dust-obscured galaxies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fan, Lulu; Gao, Ying; Zhang, Dandan

Previous studies have shown that Wide-field Infrared Survey Explorer -selected hyperluminous, hot dust-obscured galaxies (Hot DOGs) are powered by highly dust-obscured, possibly Compton-thick active galactic nuclei (AGNs). High obscuration provides us a good chance to study the host morphology of the most luminous AGNs directly. We analyze the host morphology of 18 Hot DOGs at z ∼ 3 using Hubble Space Telescope /WFC3 imaging. We find that Hot DOGs have a high merger fraction (62 ± 14%). By fitting the surface brightness profiles, we find that the distribution of Sérsic indices in our Hot DOG sample peaks around 2, whichmore » suggests that most Hot DOGs have transforming morphologies. We also derive the AGN bolometric luminosity (∼10{sup 14} L {sub ⊙}) of our Hot DOG sample by using IR spectral energy distributions decomposition. The derived merger fraction and AGN bolometric luminosity relation is well consistent with the variability-based model prediction. Both the high merger fraction in an IR-luminous AGN sample and relatively low merger fraction in a UV/optical-selected, unobscured AGN sample can be expected in the merger-driven evolutionary model. Finally, we conclude that Hot DOGs are merger-driven and may represent a transit phase during the evolution of massive galaxies, transforming from the dusty starburst-dominated phase to the unobscured QSO phase.« less

Solution or suspension - Does it matter for lipid based systems? In vivo studies of chase dosing lipid vehicles with aqueous suspensions of a poorly soluble drug.

PubMed

Larsen, A T; Holm, R; Müllertz, A

2017-08-01

In this study, the potential of co-administering an aqueous suspension with a placebo lipid vehicle, i.e. chase dosing, was investigated in rats relative to the aqueous suspension alone or a solution of the drug in the lipid vehicle. The lipid investigated in the present study was Labrafil M2125CS and three evaluated poorly soluble model compounds, danazol, cinnarizine and halofantrine. For cinnarizine and danazol the oral bioavailability in rats after chase dosing or dosing the compound dissolved in Labrafil M21515CS was similar and significantly higher than for the aqueous suspension. For halofantrine the chase dosed group had a tendency towards a low bioavailability relative to the Labrafil M2125CS solution, but still a significant higher bioavailability relative to the aqueous suspension. This could be due to factors such as a slower dissolution rate in the intestinal phase of halofantrine or a lower solubility in the colloidal structures formed during digestion, but other mechanisms may also be involved. The study thereby supported the potential of chase dosing as a potential dosing regimen in situations where it is beneficial to have a drug in the solid state, e.g. due to chemical stability issues in the lipid vehicle. Copyright © 2017 Elsevier B.V. All rights reserved.

Galaxies Burn Bright Like High-Wattage Light Bulbs

NASA Image and Video Library

2012-08-29

NASA WISE has identified about 1,000 extremely obscured objects over the sky, as marked by the magenta symbols. These hot dust-obscured galaxies, or hot DOGs, are turning out to be among the most luminous.

How fast can an AGN shut down? XMM-Newton observation of IC 2497

NASA Astrophysics Data System (ADS)

Schawinski, Kevin

2008-10-01

We propose to observe IC 2497 with XMM-Newton to detect, or rule out, an obscured AGN that might account for the illumination of `Hanny's Voorwerp'. The Voorwerp is a highly ionised cloud of gas extended over 15-25 kpc next to the spiral galaxy IC 2497. There is no source of ionisation within the Voorwerp, implicating a luminous 1E44 erg/s AGN in IC 2497 as the source. Swift XRT observations do not yield a detection, allowing the presence of a highly obscured, sufficiently luminous AGN. With 34 ksec of XMM observations, we could detect an obscured AGN down to 1E42 erg/s. We can thus either locate an obscured AGN, or we can for the first time constrain the shutdown time scale for a powerful AGN, as it drops by a factor of 100 in luminosity in 1E5 years.

Chinese Learning Journeys: Chasing the Dream

ERIC Educational Resources Information Center

Su, Feng, Ed.

2011-01-01

Eight students from mainland China chart their learning journeys across national and continental boundaries and socio-cultural contexts. The five women and three men structure their experiences of studying in China and the West around the turning points and life changing choices they made in chasing their dreams. They embody its emergent…

What Do Tag Games Teach?

ERIC Educational Resources Information Center

Belka, David

2006-01-01

Tag games have been described as "Chasing, fleeing, and dodging" type activities. Most "fleeing" activities involve dramatic play, use of movement concepts (such as quick and light), or movement changes without a partner, while many of the chasing and dodging activities utilize dodging concepts between partners or within small groups and are…

78 FR 18801 - Establishment of Class E Airspace; Beeville, TX

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-28

... Instrument Approach Procedures at Chase Field Industrial Airport. The FAA is taking this action to enhance the safety and management of Instrument Flight Rule (IFR) operations at the airport. DATES: Effective... Federal Register a notice of proposed rulemaking (NPRM) to establish Class E airspace at Chase Industrial...

Dusty Quasars at High Redshifts

NASA Astrophysics Data System (ADS)

Weedman, Daniel; Sargsyan, Lusine

2016-09-01

A population of quasars at z ˜ 2 is determined based on dust luminosities νL ν (7.8 μm) that includes unobscured, partially obscured, and obscured quasars. Quasars are classified by the ratio νL ν (0.25 μm)/νL ν (7.8 μm) = UV/IR, assumed to measure obscuration of UV luminosity by the dust that produces IR luminosity. Quasar counts at rest-frame 7.8 μm are determined for quasars in the Boötes field of the NOAO Deep Wide Field Survey using 24 μm sources with optical redshifts from the AGN and Galaxy Evolution Survey (AGES) or infrared redshifts from the Spitzer Infrared Spectrograph. Spectral energy distributions are extended to far-infrared wavelengths using observations from the Herschel Space Observatory Spectral and Photometric Imaging Receiver (SPIRE), and new SPIRE photometry is presented for 77 high-redshift quasars from the Sloan Digital Sky Survey. It is found that unobscured and obscured quasars have similar space densities at rest-frame 7.8 μm, but the ratio L ν (100 μm)/L ν (7.8 μm) is about three times higher for obscured quasars than for unobscured, so that far-infrared or submillimeter quasar detections are dominated by obscured quasars. We find that only ˜5% of high-redshift submillimeter sources are quasars and that existing 850 μm surveys or 2 mm surveys should already have detected sources at z ˜ 10 if quasar and starburst luminosity functions remain the same from z = 2 until z = 10.

The effects of brefeldin-A on the high mannose oligosaccharides of mouse thyrotropin, free alpha-subunits, and total glycoproteins.

PubMed

Perkel, V S; Liu, A Y; Miura, Y; Magner, J A

1988-07-01

We have studied the effects of Brefeldin-A (BFA) on the processing of high mannose (Man) oligosaccharides of TSH. BFA is a drug that inhibits the intracellular translocation of newly synthesized glycoproteins and causes dilatation of the rough endoplasmic reticulum (RER) as well as mild swelling of the Golgi apparatus. Mouse pituitary thyrotropic tumor tissue was incubated with [3H]Man for a 2-h pulse, with and without a 3-h chase; BFA (5 micrograms/ml) was included during selected pulse and selected chase incubations. TSH and free alpha-subunits were obtained from detergent lysates of tissue by immunoprecipitation using specific antisera. Total glycoproteins were obtained by trichloroacetic acid precipitation. Endoglycosidase-H-released [3H]oligosaccharides were analyzed by paper chromatography. BFA inhibited carbohydrate processing of TSH, free alpha-subunits, and total glycoproteins, resulting in the accumulation of Man8GlcNAc2, Man7GlcNAc2, Man6GlcNAc2, and Man5GlcNAc2, especially during the chase period. Subcellular fractions enriched in RER, heavy (proximal) Golgi, and light (distal) Golgi were prepared by centrifugation in discontinuous sucrose gradients. [3H]Man-labeled oligosaccharides of TSH and total glycoproteins in the subcellular fractions were analyzed. In contrast to oligosaccharides with eight or nine Man residues found in control incubations, BFA caused the accumulation of oligosaccharides containing five to eight Man residues. These BFA-induced oligosaccharide alterations began in the RER and proximal Golgi with the 2-h pulse and extended into the distal Golgi during the chase incubations. Thus, BFA blocks the normal intracellular transport and processing of TSH, free alpha-subunits, and total glycoproteins within thyrotrophs, causing species with smaller than normal high Man oligosaccharides to appear in subcellular compartments as early as the RER. The translocation block between RER and Golgi produced by BFA may prevent the processing of Man8GlcNAc2 to Man5GlcNAc2 by Golgi (alpha,1-2)mannosidase I, yet the species retained within the RER may be subject to ongoing processing by endoplasmic reticulum (alpha,1-2)mannosidase, resulting in the accumulation of Man5-8GlcNAc2 within the RER.

Identifying Determinants of PARP Inhibitor Sensitivity in Ovarian Cancer

DTIC Science & Technology

2015-10-01

such as those lacking functional BRCA1 are highly sensitive to poly(ADP-ribose) polymerase (PARP) inhibitors. Ovarian cancer patients that harbored...Principal Investigator (Last, first, middle): Johnson, Neil  Dr. Johnson’s mentor, Dr. Jeffrey Boyd, left Fox Chase for Florida International

Aggregation increases prey survival time in group chase and escape

NASA Astrophysics Data System (ADS)

Yang, Sicong; Jiang, Shijie; Jiang, Li; Li, Geng; Han, Zhangang

2014-08-01

Recently developed chase-and-escape models have addressed a fascinating pursuit-and-evasion problem that may have both theoretical significance and potential applications. We introduce three aggregation strategies for the prey in a group chase model on a lattice. Simulation results show that aggregation dramatically increases the group survival time, even allowing immortal prey. The average survival time τ and the aggregation probability P have a power-law dependence of \\tau \\sim {{(1-P)}^{-1}} for P\\in [0.9,0.997]. With increasing numbers of predators, there is still a phase transition. When the number of predators is less than the critical point value, the prey group survival time increases significantly.

Chase and NYANA: A Partnership To Remove Barriers to Job Performance 1993-94. Final Report.

ERIC Educational Resources Information Center

Auerbach, Charles

A workplace literacy program implemented cooperatively by the New York Association for New Americans, Inc. (NYANA) and Chase Manhattan Bank is reported. The federally-funded project provided individualized communication workplace behavior and skills training in English as a Second Language for 30 limited-English-proficient bank employees working…

Motivations and sensation seeking characteristics of recreational storm chasers

Treesearch

Shuangyu Xu; Sonja Wilhelm Stanis; Carla Barbieri; Jiawen Chen

2012-01-01

Little is known about recreational storm chasing, a type of risk recreation that has increased in popularity since the 1990s. This study was conducted to understand factors associated with participation in recreational storm chasing in the United States. Particularly, this study assessed the motivations and sensation seeking attributes of recreational storm chasers, as...

X-Ray Spectral Properties of Seven Heavily Obscured Seyfert 2 Galaxies

NASA Astrophysics Data System (ADS)

Marchesi, S.; Ajello, M.; Comastri, A.; Cusumano, G.; La Parola, V.; Segreto, A.

2017-02-01

We present the combined Chandra and Swift-BAT spectral analysis of seven Seyfert 2 galaxies selected from the Swift-BAT 100 month catalog. We selected nearby (z ≤ 0.03) sources lacking a ROSAT counterpart that never previously been observed with Chandra in the 0.3-10 keV energy range, and targeted these objects with 10 ks Chandra ACIS-S observations. The X-ray spectral fitting over the 0.3-150 keV energy range allows us to determine that all the objects are significantly obscured, with N H ≥ 1023 cm-2 at a >99% confidence level. Moreover, one to three sources are candidate Compton-thick Active Galactic Nuclei (CT-AGNs; I.e., N H ≥ 1024 cm-2). We also test the recent spectral curvature method developed by Koss et al. to find candidate CT-AGNs, finding a good agreement between our results and their predictions. Because the selection criteria we adopted were effective in detecting highly obscured AGNs, further observations of these and other Seyfert 2 galaxies selected from the Swift-BAT 100 month catalog will allow us to create a statistically significant sample of highly obscured AGNs, therefore providing a better understanding of the physics of the obscuration processes.

Evidence for Merger-driven Growth in Luminous, High- z, Obscured AGNs in the CANDELS/COSMOS Field

DOE PAGES

Donley, J. L.; Kartaltepe, J.; Kocevski, D.; ...

2018-01-23

While major mergers have long been proposed as a driver of both active galactic nucleus (AGN) activity and themore » $${M}_{\\mathrm{BH}}\\mbox{--}{\\sigma }_{\\mathrm{bulge}}$$ relation, studies of moderate to high-redshift Seyfert-luminosity AGN hosts have found little evidence for enhanced rates of interactions. However, both theory and observation suggest that while these AGNs may be fueled by stochastic accretion and secular processes, high-luminosity, high-redshift, and heavily obscured AGNs are the AGNs most likely to be merger-driven. To better sample this population of AGNs, we turn to infrared selection in the CANDELS/COSMOS field. Compared to their lower-luminosity and less obscured X-ray-only counterparts, IR-only AGNs (luminous, heavily obscured AGNs) are more likely to be classified as either irregular ($${50}_{-12}^{+12} \\% $$ versus $${9}_{-2}^{+5} \\% $$) or asymmetric ($${69}_{-13}^{+9} \\% $$ versus $${17}_{-4}^{+6} \\% $$) and are less likely to have a spheroidal component ($${31}_{-9}^{+13} \\% $$ versus $${77}_{-6}^{+4} \\% $$). Furthermore, IR-only AGNs are also significantly more likely than X-ray-only AGNs ($${75}_{-13}^{+8} \\% $$ versus $${31}_{-6}^{+6} \\% $$) to be classified either as interacting or merging in a way that significantly disturbs the host galaxy or as disturbed, though not clearly interacting or merging, which potentially represents the late stages of a major merger. Finally, this suggests that while major mergers may not contribute significantly to the fueling of Seyfert-luminosity AGNs, interactions appear to play a more dominant role in the triggering and fueling of high-luminosity heavily obscured AGNs.« less

Bacillus megaterium sporal peptidoglycan synthesis studied by high-resolution autoradiography.

PubMed

Frehel, C; Ryter, A

1980-11-01

Cells of a Dap- Lys- mutant strain of Bacillus megaterium were pulse labeled with [3H]diaminopimelic acid at different times of growth and sporulation. They were processed for radioactivity measurements and high-resolution autoradiography either just after the pulse or after a chase in a nonradioactive medium until refractile forespores started to appear at time (t)4,5. In the pulse-labeled cells, autoradiographs and radioactivity measurements showed that the radioactivity incorporated during a pulse decreased abruptly after t0 and stayed at a low level until t5, although the forespore wall and cortex were formed between t4 and t5. In the pulse-chased bacteria, the acid-insoluble radioactivity, as well as the number of silver grains on autoradiographs, increased during the chase in cells labeled at t1 to t2, whereas it decreased in those labeled before t0. Furthermore, analysis of silver grain distribution showed that, in stage IV bacteria, grains were distributed at the outside of the forespore, mostly on the sporangium cell wall, when pulse-labeling occurred before or at t0; they were located along the cortex and in the forespore cytoplasm when labeling was made at t1 or t2. These facts show that [3H]diaminopimelic acid necessary for spore envelope synthesis was incorporated before their morphological appearance. Free or small diaminopimelic acid precursors entered the sporangium between t1 and t2. The appearance of silver grains in the forespore cytoplasm suggests that the forespore is implicated in sporal peptidoglycan synthesis.

Maternal programming of offspring hypothalamic-pituitary-interrenal axis in wild sockeye salmon (Oncorhynchus nerka).

PubMed

Sopinka, N M; Jeffrey, J D; Burnett, N J; Patterson, D A; Gilmour, K M; Hinch, S G

2017-02-01

In fishes, maternal exposure to a stressor can influence offspring size and behavior. However, less is known about how maternal stress influences physiological processes in offspring, such as function of the hypothalamic-pituitary-interrenal (HPI) axis. We examined the impact of chronic maternal exposure to an acute chase stressor on the stress response/HPI activity of progeny in wild sockeye salmon (Oncorhynchus nerka). Resting plasma cortisol and brain preoptic area (POA) corticotropin-releasing factor (CRF) mRNA levels did not vary between offspring reared from undisturbed, control females and offspring reared from females exposed to the stressor. However, resting levels of POA glucocorticoid receptors (GR1 and GR2), and head kidney melanocortin 2 receptor (MC2R), steroidogenic acute regulatory protein (StAR), and cytochrome P450 side chain cleavage enzyme (P450scc) were elevated in offspring reared from stressor-exposed females. Offspring reared from stressor-exposed females had lower plasma cortisol levels 1-h after an acute chase stressor compared to cortisol levels in offspring reared from control females. In offspring reared from chased females, mRNA levels of genes associated with cortisol biosynthesis were reduced in the head kidney post-chase. In offspring reared from control females, mRNA levels in the head kidney did not vary pre- to post-chase. Together, the results of the present study suggest maternal programming of progeny with respect to baseline and stressor-induced mediators of HPI axis activity. Copyright © 2015 Elsevier Inc. All rights reserved.

Predator evasion by white-tailed deer fawns

USGS Publications Warehouse

Grovenburg, Troy W.; Monteith, Kevin L.; Klaver, Robert W.; Jenks, Jonathan A.

2012-01-01

Despite their importance for understanding predator–prey interactions, factors that affect predator evasion behaviours of offspring of large ungulates are poorly understood. Our objective was to characterize the influence of selection and availability of escape cover and maternal presence on predator evasion by white-tailed deer, Odocoileus virginianus, fawns in the northern Great Plains, U.S.A. We observed 45 coyote, Canis latrans, chases of fawns, and we participated in 83 human chases of fawns during 2007–2009, of which, 19 and 42 chases, respectively, ended with capture of the fawn. Evasive techniques used by fawns were similar for human and coyote chases. Likelihood of a white-tailed deer fawn escaping capture, however, was influenced by deer group size and a number of antipredator behaviours, including aggressive defence by females, initial habitat and selection of escape cover, all of which were modified by the presence of parturient females. At the initiation of a chase, fawns in grasslands were more likely to escape, whereas fawns in forested cover, cultivated land or wheat were more likely to be captured by a coyote or human. Fawns fleeing to wetlands and grasslands also were less likely to be captured compared with those choosing forested cover, wheat and cultivated land. Increased probability of capture was associated with greater distance to wetland and grassland habitats and decreased distance to wheat. Use of wetland habitat as a successful antipredator strategy highlights the need for a greater understanding of the importance of habitat complexity in predator avoidance.

EC79-11481

NASA Image and Video Library

1979-08-20

A chase plane view of the tufts on the KC-135 winglet. The use of tufts in flight research dates back to the early days of the NACA, and remains an effective means of observing airflow even today. In this procedure, rows of strings are attached to an airplane's surface, with one end of each string taped to the airplane and the other end free to swing about in the airflow. The movements of the tufts are photographed by on-board cameras or a chase plane. If the tufts are arrayed in neat rows, as seen here, then the airflow is smooth over the airplane's surface. If, however, they are moving about violently, it suggests turbulent airflow. Such motions may indicate high drag, flow separation (such as in a stall), or buffeting. In some cases, tufts will actually point forward, indicating the airflow has reversed direction.

Sexually dimorphic aggression indicates male gray wolves specialize in pack defense against conspecific groups

USGS Publications Warehouse

Cassidy, Kira A.; Mech, L. David; MacNulty, Daniel R; Stahler, Daniel R.; Smith, Douglas W.

2017-01-01

Aggression directed at conspecific groups is common among gregarious, territorial species, and for some species such as gray wolves (Canis lupus) intraspecific strife is the leading cause of natural mortality. Each individual in a group likely has different measures of the costs and benefits associated with a group task, such as an aggressive attack on another group, which can alter motivation and behavior. We observed 292 inter-pack aggressive interactions in Yellowstone National Park between 1 April 1995 and 1 April 2011 (>5300 days of observation) in order to determine the role of both sexes, and the influence of pack, age, and other traits on aggression. We recorded the behaviors and characteristics of all individuals present during the interactions (n = 534 individuals) and which individuals participated in each step (i.e. chase, attack, kill, flight) of the interaction. Overall, all wolves were more likely to chase rivals if they outnumbered their opponent, suggesting packs accurately assess their opponent’s size during encounters and individuals adjust their behavior based on relative pack size. Males were more likely than females to chase rival packs and gray-colored wolves were more aggressive than black-colored wolves. Male wolves and gray-colored wolves also recorded higher cortisol levels than females and black-colored wolves, indicating hormonal support for more intense aggressive behavior. Further, we found a positive correlation between male age and probability of chasing, while age-specific participation for females remained constant. Chasing behavior was influenced by the sex of lone intruders, with males more likely to chase male intruders. This difference in behavior suggests male and female wolves may have different strategies and motivations during inter-pack aggressive interactions related to gray wolf mating systems. A division of labor between pack members concerning resource and territory defense suggests selection for specific traits related to aggression is an adaptive response to intense competition between groups of conspecifics.

Sexually dimorphic aggression indicates male gray wolves specialize in pack defense against conspecific groups.

PubMed

Cassidy, Kira A; Mech, L David; MacNulty, Daniel R; Stahler, Daniel R; Smith, Douglas W

2017-03-01

Aggression directed at conspecific groups is common among gregarious, territorial species, and for some species such as gray wolves (Canis lupus) intraspecific strife is the leading cause of natural mortality. Each individual in a group likely has different measures of the costs and benefits associated with a group task, such as an aggressive attack on another group, which can alter motivation and behavior. We observed 292 inter-pack aggressive interactions in Yellowstone National Park between 1 April 1995 and 1 April 2011 (>5300days of observation) in order to determine the role of both sexes, and the influence of pack, age, and other traits on aggression. We recorded the behaviors and characteristics of all individuals present during the interactions (n=534 individuals) and which individuals participated in each step (i.e. chase, attack, kill, flight) of the interaction. Overall, all wolves were more likely to chase rivals if they outnumbered their opponent, suggesting packs accurately assess their opponent's size during encounters and individuals adjust their behavior based on relative pack size. Males were more likely than females to chase rival packs and gray-colored wolves were more aggressive than black-colored wolves. Male wolves and gray-colored wolves also recorded higher cortisol levels than females and black-colored wolves, indicating hormonal support for more intense aggressive behavior. Further, we found a positive correlation between male age and probability of chasing, while age-specific participation for females remained constant. Chasing behavior was influenced by the sex of lone intruders, with males more likely to chase male intruders. This difference in behavior suggests male and female wolves may have different strategies and motivations during inter-pack aggressive interactions related to gray wolf mating systems. A division of labor between pack members concerning resource and territory defense suggests selection for specific traits related to aggression is an adaptive response to intense competition between groups of conspecifics. Copyright © 2017 Elsevier B.V. All rights reserved.

Principal as Curriculum Leader: Chase Manhattan Project.

ERIC Educational Resources Information Center

Petruzillo, Eileen; Scheinbart, Diane S.

1986-01-01

Describes a program initiated at a high school in New York City that identified learning styles of special education students in an effort to increase their achievement. Concludes that the program led to gains in motivation as well as achievement. Contains materials used to identify learning styles. (FL)

Tumor-specific detection of an optically targeted antibody combined with a quencher-conjugated neutravidin "quencher-chaser": a dual "quench and chase" strategy to improve target to nontarget ratios for molecular imaging of cancer.

PubMed

Ogawa, Mikako; Kosaka, Nobuyuki; Choyke, Peter L; Kobayashi, Hisataka

2009-01-01

In vivo molecular cancer imaging with monoclonal antibodies has great potential not only for cancer detection, but also for cancer characterization. However, the prolonged retention of intravenously injected antibody in the blood causes low target tumor-to-background ratio (TBR). Avidin has been used as a "chase" to clear the unbound, circulating biotinylated antibody and decrease the background signal. Here, we utilize a combined approach of a fluorescence resonance energy transfer (FRET) quenched antibody with an "avidin chase" to increase TBR. Trastuzumab, a humanized monoclonal antibody against human epidermal growth factor receptor type 2 (HER2), was biotinylated and conjugated with the near-infrared (NIR) fluorophore Alexa680 to synthesize Tra-Alexa680-biotin. Next, the FRET quencher, QSY-21, was conjugated to avidin, neutravidin (nAv), or streptavidin (sAv), thus creating Av-QSY21, nAv-QSY21, or sAv-QSY21 as "chasers". The fluorescence was quenched in vitro by binding Tra-Alexa680-biotin to Av-QSY21, nAv-QSY21, or sAv-QSY21. To evaluate if the injection of quencher-conjugated avidin derivatives can improve target TBR by using a dual "quench and chase" strategy, both target (3T3/HER2+) and nontarget (Balb3T3/ZsGreen) tumor-bearing mice were employed. The "FRET quench" effect induced by all the QSY21 avidin-based conjugates reduced but did not totally eliminate background signal from the blood pool. The addition of nAv-QSY21 administration increased target TBR mainly because of the "chase" effect where unbound conjugated antibody was preferentially cleared to the liver. The relatively slow clearance of unbound nAv-QSY21 leads to further reductions in background signal by leaking out of the vascular space and binding to unbound antibodies in the extravascular space of tumors, resulting in decreased nontarget tumor-to-background ratios but increased target TBR due to the "FRET quench" effect, because target-bound antibodies were internalized and could not bind to nAv-QSY21. In conclusion, the proposed "quench-and-chase" system combines two strategies, fluorescent quenching and avidin chasing, to improve target TBR and reduce nontarget TBR, which should result in both improved tumor sensitivity and improved specificity.

F-18 chase craft with NASA test pilots Schneider and Fulton

NASA Technical Reports Server (NTRS)

1992-01-01

Ed Schneider, (left), is the project pilot for the F-18 High Angle of Attack program at NASA's Dryden Flight Research Center, Edwards, California. He has been a NASA research pilot at Dryden since 1983. In addition to his assignment with the F-18 High Angle of Attack program, Schneider is a project pilot for the F-15B aeronautical research aircraft, the NASA NB-52B launch aircraft, and the SR-71 'Blackbird' aircraft. He is a Fellow and was the 1994 President of the Society of Experimental Test Pilots. In 1996 he was awarded the NASA Exceptional Service Medal. Schneider is seen here with Fitzhugh L. Fulton Jr., (right), who was a civilian research pilot at Dryden. from August 1, 1966, until July 3, 1986, following 23 years of service as a pilot in the U.S. Air Force. Fulton was the project pilot on all early tests of the 747 Shuttle Carrier Aircraft (SCA) used to air launch the Space Shuttle prototype Enterprise in the Approach and Landing Tests (ALT) at Dryden in l977. For his work in the ALT program, Fulton received NASA's Exceptional Service Medal. He also received the Exceptional Service Medal again in 1983 for flying the 747 SCA during the European tour of the Space Shuttle Enterprise. During his career at Dryden, Fulton was project pilot on NASA's NB-52B launch aircraft used to air launch a variety of piloted and unpiloted research aircraft, including the X-15s and lifting bodies. He flew the XB-70 prototype supersonic bomber on both NASA-USAF tests and NASA research flights during the late 1960s, attaining speeds exceeding Mach 3. He was also a project pilot on the YF-12A and YF-12C research program from April 14, 1969, until September 25, 1978. The F/A-18 Hornet seen behind them is used primarily as a safety chase and support aircraft at NASA's Dryden Flight Research Center, Edwards, Calif. As support aircraft, the F-18's are used for safety chase, pilot proficiency and aerial photography. As a safety chase aircraft, F-18's, flown by research pilots, accompany research missions as another 'set of eyes' to visually observe the research event, experiment or test to help make sure the flights are carried out safely. The 'chase' pilots are in constant communication with the research pilots and mission control to report abnormalities that may be seen from the support aircraft. Pilots must also stay proficient by flying a certain number of missions per month. F-18's are used for this. A two-seat support aircraft is also used when research missions require an engineer or photographer on the flights.

77 FR 45690 - Exemptions From Certain Prohibited Transaction Restrictions

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-01

... is made by a Plan fiduciary or Plan participant or IRA owner who is independent (as defined in... process; (d) A person is ``independent'' of JPMorgan Chase if the person is: (1) Not JPMorgan Chase or an... independent act of SPF as a corporate entity for business reasons which did not involve the Plan. As such, all...

Scenes of Devastation: Chasing Hawaii's Deadly Ohia Fungus | Hawaii Public

Science.gov Websites

Scenes of Devastation: Chasing Hawaii's Deadly Ohia Fungus By Molly Solomon * Mar 25, 2016 TweetShareGoogle+Email Molly Solomon Rapid Ohia Death has devastated native forests on Hawaii Island, especially in Lower Puna subdivisions like Leilani Estates. Credit Molly Solomon One of Hawai'i's oldest and most

76 FR 31955 - Jonathan and Jayne Chase; Notice of Application Accepted for Filing With the Commission, Intent...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-02

.... c. Date filed: July 23, 2010. d. Applicant: Jonathan and Jayne Chase. e. Name of Project: Troy Hydropower Project. f. Location: On the Missisquoi River, in the Town of Troy, Orleans County, Vermont. The... filing and is now ready for environmental analysis. l. Project Description: The Troy Project would...

The Psychophysics of Chasing: A Case Study in the Perception of Animacy

ERIC Educational Resources Information Center

Gao, Tao; Newman, George E.; Scholl, Brian J.

2009-01-01

Psychologists have long been captivated by the perception of animacy--the fact that even simple moving shapes may appear to engage in animate, intentional, and goal-directed movements. Here we report several new types of studies of a particularly salient form of perceived animacy: "chasing", in which one shape (the "wolf") pursues another shape…

Observations and reinterpretation of kingfisher-raptor interactions

USGS Publications Warehouse

Kirby, Ronald E.; Fuller, Mark R.

1978-01-01

Reported observations of Belted Kingfisher (Megaceryle alcyon)-raptor interactions have ranged from brief encounters where the kingfisher escaped the raptor and the hawk subsequently flew away to repeated chases (Johnson 1925, McCabe and McCabe 1928, Skinner 1928, Smith 1963). In some repetitive chases, kingfishers appeared to initiate the interaction (McCabe and McCabe 1928, Skinner 1928).

Engaging Experiential Service Learning through a Co-Curricular Club: The Chase Charlie Races

ERIC Educational Resources Information Center

Judge, Lawrence W.; Pierce, David; Petersen, Jeffrey; Bellar, David; Wanless, Elizabeth; Gilreath, Erin; Simon, Laura

2011-01-01

The efficacy of the "Chase Charlie Races" (an experiential learning activity) was demonstrated via program assessment. This was achieved via post-event evaluations of race participants and student club members, and with fitness assessments of 76 elementary students who participated in an eight-week training program. Paired sample t-tests revealed…

T-34C in flight

NASA Image and Video Library

1997-03-21

A NASA T-34C aircraft, used for safety chase, is shown flying above the Dryden Flight Research Center, Edwards, California in March 1997. The aircraft was previously used at the Lewis Research Center in propulsion experiments involving turboprop engines, and was used as a chase aircraft at Dryden for smaller and slower research projects. Chase aircraft accompany research flights for photography and video purposes, and also as support for safety and research. At Dryden, the T-34 is used mainly for smaller remotely piloted vehicles which fly slower than NASA's F-18's, used for larger scale projects. This aircraft was returned to the U.S. Navy in May of 2002. The T-34C, built by Beech, carries a crew of 2 and is nicknamed the Mentor.

Mildly obscured active galaxies and the cosmic X-ray background

NASA Astrophysics Data System (ADS)

Esposito, V.; Walter, R.

2016-05-01

Context. The diffuse cosmic X-ray background (CXB) is the sum of the emission of discrete sources, mostly massive black-holes accreting matter in active galactic nuclei (AGN). The CXB spectrum differs from the integration of the spectra of individual sources, calling for a large population, undetected so far, of strongly obscured Compton-thick AGN. Such objects are predicted by unified models, which attribute most of the AGN diversity to their inclination on the line of sight, and play an important role for the understanding of the growth of black holes in the early Universe. Aims: The percentage of strongly obscured Compton-thick AGN at low redshift can be derived from the observed CXB spectrum, if we assume AGN spectral templates and luminosity functions. Methods: We show that high signal-to-noise stacked hard X-ray spectra, derived from more than a billion seconds of effective exposure time with the Swift/BAT instrument, imply that mildly obscured Compton-thin AGN feature a strong reflection and contribute massively to the CXB. Results: A population of Compton-thick AGN larger than that which is effectively detected is not required to reproduce the CXB spectrum, since no more than 6% of the CXB flux can be attributed to them. The stronger reflection observed in mildly obscured AGN suggests that the covering factor of the gas and dust surrounding their central engines is a key factor in shaping their appearance. These mildly obscured AGN are easier to study at high redshift than Compton-thick sources are.

Evaluation of diesel fleet emissions and control policies from plume chasing measurements of on-road vehicles

NASA Astrophysics Data System (ADS)

Lau, Chui Fong; Rakowska, Agata; Townsend, Thomas; Brimblecombe, Peter; Chan, Tat Leung; Yam, Yat Shing; Močnik, Griša; Ning, Zhi

2015-12-01

Vehicle emissions are an important source of urban air pollution. Diesel fuelled vehicles, although constituting a relatively small fraction of fleet population in many cities, are significant contributors to the emission inventory due to their often long mileage for goods and public transport. Recent classification of diesel exhaust as carcinogenic by the World Health Organization also raises attention to more stringent control of diesel emissions to protect public health. Although various mandatory and voluntary based emission control measures have been implemented in Hong Kong, there have been few investigations to evaluate if the fleet emission characteristics have met desired emission reduction objectives and if adoption of an Inspection/Maintenance (I/M) programme has been effective in achieving these objectives. The limitations are partially due to the lack of cost-effective approaches for the large scale characterisation of fleet based emissions to assess the effectiveness of control measures and policy. This study has used a plume chasing method to collect a large amount of on-road vehicle emission data of Hong Kong highways and a detailed analysis was carried out to provide a quantitative evaluation of the emission characteristics in terms of the role of high and super-emitters in total emission reduction, impact of after-treatment on the multi-pollutants reduction strategy and the trend of NO2 emissions with newer emission standards. The study revealed that not all the high-emitters are from those vehicles of older Euro emission standards. Meanwhile, there is clear evidence that high-emitters for one pollutant may not be a high-emitter for another pollutant. Multi-pollutant control strategy needs to be considered in the enactment of the emission control policy which requires more comprehensive retrofitting technological solutions and matching I/M programme to ensure the proper maintenance of fleets. The plume chasing approach used in this study also shows to be a useful approach for assessing city wide vehicle emission characteristics.

Game Changer: Linked Learning Detroit

ERIC Educational Resources Information Center

ConnectEd: The California Center for College and Career, 2016

2016-01-01

JP Morgan Chase joins the Skillman Foundation, the Ford Foundation, and the Ford Motor Company Fund, whose grants total $7 million and will connect 10,000 Detroit high school students to career education and work experiences over the next three years through Linked Learning Detroit. Learn about Linked Learning Detroit through interviews with…

Pegasus Engine Ignites after Drop from B-52 Mothership

NASA Image and Video Library

1991-07-17

Against the midnight blue of a high-altitude sky, Orbital Sciences’ Pegasus winged rocket booster ignites after being dropped from NASA’s B-52 mothership on a July 1991 flight. A NASA chase plane for the flight is also visible above the rocket and below the B-52.

THE EFFECT OF OZONE ON BELOW-GROUND CARBON ALLOCATION IN WHEAT

EPA Science Inventory

Short term 14CO2 pulse and chase experiments were conducted in order to investigate the effect ozone on below-ground carbon allocation in spring wheat seedlings (Triticum aestivumL. ?ANZA'). Wheat seedlings were grown in a sand-hydroponic system and exposed to either high ozone ...

Chasing Personal Meaning: Pedagogical Lessons through Luis Rodriguez's "Always Running"

ERIC Educational Resources Information Center

Theisen-Homer, Victoria

2014-01-01

In this autobiographical narrative, the author recounts her experiences teaching the novel "Always Running" by Luis Rodriguez with her English classes at a high school in a gang-heavy area. When she first started teaching, this teacher struggled to engage students. One particularly disruptive student requested to read "Always…

The NuSTAR Serendipitous Survey: Hunting for the Most Extreme Obscured AGN at >10 keV

NASA Astrophysics Data System (ADS)

Lansbury, G. B.; Alexander, D. M.; Aird, J.; Gandhi, P.; Stern, D.; Koss, M.; Lamperti, I.; Ajello, M.; Annuar, A.; Assef, R. J.; Ballantyne, D. R.; Baloković, M.; Bauer, F. E.; Brandt, W. N.; Brightman, M.; Chen, C.-T. J.; Civano, F.; Comastri, A.; Del Moro, A.; Fuentes, C.; Harrison, F. A.; Marchesi, S.; Masini, A.; Mullaney, J. R.; Ricci, C.; Saez, C.; Tomsick, J. A.; Treister, E.; Walton, D. J.; Zappacosta, L.

2017-09-01

We identify sources with extremely hard X-ray spectra (I.e., with photon indices of {{Γ }}≲ 0.6) in the 13 deg2 NuSTAR serendipitous survey, to search for the most highly obscured active galactic nuclei (AGNs) detected at > 10 {keV}. Eight extreme NuSTAR sources are identified, and we use the NuSTAR data in combination with lower-energy X-ray observations (from Chandra, Swift XRT, and XMM-Newton) to characterize the broadband (0.5-24 keV) X-ray spectra. We find that all of the extreme sources are highly obscured AGNs, including three robust Compton-thick (CT; {N}{{H}}> 1.5× {10}24 cm-2) AGNs at low redshift (z< 0.1) and a likely CT AGN at higher redshift (z = 0.16). Most of the extreme sources would not have been identified as highly obscured based on the low-energy (< 10 keV) X-ray coverage alone. The multiwavelength properties (e.g., optical spectra and X-ray-mid-IR luminosity ratios) provide further support for the eight sources being significantly obscured. Correcting for absorption, the intrinsic rest-frame 10-40 keV luminosities of the extreme sources cover a broad range, from ≈ 5× {10}42 to 1045 erg s-1. The estimated number counts of CT AGNs in the NuSTAR serendipitous survey are in broad agreement with model expectations based on previous X-ray surveys, except for the lowest redshifts (z< 0.07), where we measure a high CT fraction of {f}{CT}{obs}={30}-12+16 % . For the small sample of CT AGNs, we find a high fraction of galaxy major mergers (50% ± 33%) compared to control samples of “normal” AGNs.

CHASE Survey of Technology Needs

DTIC Science & Technology

2017-03-01

CHASE Survey of Technology Needs Shahed Enamul Quadir ECE Department University of Connecticut Storrs, CT, USA Daniel DiMase Honeywell, Inc...based on a survey conducted in late 2015. Counterfeits and Hardware Trojans have been identified as areas needing continued research and focus... survey of its advisory board and industry professionals to determine the technology needs in the area of IC counterfeits, hardware assurance

Saying the Right Word at the Right Time: Syntagmatic and Paradigmatic Interference in Sentence Production

ERIC Educational Resources Information Center

Dell, Gary S.; Oppenheim, Gary M.; Kittredge, Audrey K.

2008-01-01

Retrieving a word in a sentence requires speakers to overcome syntagmatic, as well as paradigmatic interference. When accessing "cat" in "The cat chased the string", not only are similar competitors such as "dog" and "cap" activated, but also other words in the planned sentence, such as "chase" and "string". We hypothesise that both types of…

Cheetahs, Acinonyx jubatus, balance turn capacity with pace when chasing prey

PubMed Central

Wilson, John W.; Mills, Michael G. L.; Wilson, Rory P.; Peters, Gerrit; Mills, Margaret E. J.; Speakman, John R.; Durant, Sarah M.; Bennett, Nigel C.; Marks, Nikki J.; Scantlebury, Michael

2013-01-01

Predator–prey interactions are fundamental in the evolution and structure of ecological communities. Our understanding, however, of the strategies used in pursuit and evasion remains limited. Here, we report on the hunting dynamics of the world's fastest land animal, the cheetah, Acinonyx jubatus. Using miniaturized data loggers, we recorded fine-scale movement, speed and acceleration of free-ranging cheetahs to measure how hunting dynamics relate to chasing different sized prey. Cheetahs attained hunting speeds of up to 18.94 m s−1 and accelerated up to 7.5 m s−2 with greatest angular velocities achieved during the terminal phase of the hunt. The interplay between forward and lateral acceleration during chases showed that the total forces involved in speed changes and turning were approximately constant over time but varied with prey type. Thus, rather than a simple maximum speed chase, cheetahs first accelerate to decrease the distance to their prey, before reducing speed 5–8 s from the end of the hunt, so as to facilitate rapid turns to match prey escape tactics, varying the precise strategy according to prey species. Predator and prey thus pit a fine balance of speed against manoeuvring capability in a race for survival. PMID:24004493

Cheetahs, Acinonyx jubatus, balance turn capacity with pace when chasing prey.

PubMed

Wilson, John W; Mills, Michael G L; Wilson, Rory P; Peters, Gerrit; Mills, Margaret E J; Speakman, John R; Durant, Sarah M; Bennett, Nigel C; Marks, Nikki J; Scantlebury, Michael

2013-10-23

Predator-prey interactions are fundamental in the evolution and structure of ecological communities. Our understanding, however, of the strategies used in pursuit and evasion remains limited. Here, we report on the hunting dynamics of the world's fastest land animal, the cheetah, Acinonyx jubatus. Using miniaturized data loggers, we recorded fine-scale movement, speed and acceleration of free-ranging cheetahs to measure how hunting dynamics relate to chasing different sized prey. Cheetahs attained hunting speeds of up to 18.94 m s(-1) and accelerated up to 7.5 m s(-2) with greatest angular velocities achieved during the terminal phase of the hunt. The interplay between forward and lateral acceleration during chases showed that the total forces involved in speed changes and turning were approximately constant over time but varied with prey type. Thus, rather than a simple maximum speed chase, cheetahs first accelerate to decrease the distance to their prey, before reducing speed 5-8 s from the end of the hunt, so as to facilitate rapid turns to match prey escape tactics, varying the precise strategy according to prey species. Predator and prey thus pit a fine balance of speed against manoeuvring capability in a race for survival.

A open loop guidance architecture for navigationally robust on-orbit docking

NASA Technical Reports Server (NTRS)

Chern, Hung-Sheng

1995-01-01

The development of an open-hop guidance architecture is outlined for autonomous rendezvous and docking (AR&D) missions to determine whether the Global Positioning System (GPS) can be used in place of optical sensors for relative initial position determination of the chase vehicle. Feasible command trajectories for one, two, and three impulse AR&D maneuvers are determined using constrained trajectory optimization. Early AR&D command trajectory results suggest that docking accuracies are most sensitive to vertical position errors at the initial conduction of the chase vehicle. Thus, a feasible command trajectory is based on maximizing the size of the locus of initial vertical positions for which a fixed sequence of impulses will translate the chase vehicle into the target while satisfying docking accuracy requirements. Documented accuracies are used to determine whether relative GPS can achieve the vertical position error requirements of the impulsive command trajectories. Preliminary development of a thruster management system for the Cargo Transfer Vehicle (CTV) based on optimal throttle settings is presented to complete the guidance architecture. Results show that a guidance architecture based on a two impulse maneuvers generated the best performance in terms of initial position error and total velocity change for the chase vehicle.

Global Positioning System Synchronized Active Light Autonomous Docking System

NASA Technical Reports Server (NTRS)

Howard, Richard T. (Inventor); Book, Michael L. (Inventor); Bryan, Thomas C. (Inventor); Bell, Joseph L. (Inventor)

1996-01-01

A Global Positioning System Synchronized Active Light Autonomous Docking System (GPSSALADS) for automatically docking a chase vehicle with a target vehicle comprising at least one active light emitting target which is operatively attached to the target vehicle. The target includes a three-dimensional array of concomitantly flashing lights which flash at a controlled common frequency. The GPSSALADS further comprises a visual tracking sensor operatively attached to the chase vehicle for detecting and tracking the target vehicle. Its performance is synchronized with the flash frequency of the lights by a synchronization means which is comprised of first and second internal clocks operatively connected to the active light target and visual tracking sensor, respectively, for providing timing control signals thereto, respectively. The synchronization means further includes first and second Global Positioning System receivers operatively connected to the first and second internal clocks, respectively, for repeatedly providing simultaneous synchronization pulses to the internal clocks, respectively. In addition, the GPSSALADS includes a docking process controller means which is operatively attached to the chase vehicle and is responsive to the visual tracking sensor for producing commands for the guidance and propulsion system of the chase vehicle.

Global Positioning System Synchronized Active Light Autonomous Docking System

NASA Technical Reports Server (NTRS)

Howard, Richard (Inventor)

1994-01-01

A Global Positioning System Synchronized Active Light Autonomous Docking System (GPSSALADS) for automatically docking a chase vehicle with a target vehicle comprises at least one active light emitting target which is operatively attached to the target vehicle. The target includes a three-dimensional array of concomitantly flashing lights which flash at a controlled common frequency. The GPSSALADS further comprises a visual tracking sensor operatively attached to the chase vehicle for detecting and tracking the target vehicle. Its performance is synchronized with the flash frequency of the lights by a synchronization means which is comprised of first and second internal clocks operatively connected to the active light target and visual tracking sensor, respectively, for providing timing control signals thereto, respectively. The synchronization means further includes first and second Global Positioning System receivers operatively connected to the first and second internal clocks, respectively, for repeatedly providing simultaneous synchronization pulses to the internal clocks, respectively. In addition, the GPSSALADS includes a docking process controller means which is operatively attached to the chase vehicle and is responsive to the visual tracking sensor for producing commands for the guidance and propulsion system of the chase vehicle.

Turnover of galactans and other cell wall polysaccharides during development of flax plants

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gorshkova, T.A.; Chemikosova, S.B.; Lozovaya, V.V.

1997-06-01

We investigated the synthesis and turnover of cell wall polysaccharides of the flax (Linum usitatissimum L.) plant during development of the phloem fibers. One-month-old flax plants were exposed to a 40-min pulse with {sup 14}CO{sub 2} followed by 8-h, 24-h, and 1-month periods of chase with ambient CO{sub 2}, and radioactivity in cell wall sugars was determined in various plant parts. The relative radioactivity of glucose in noncellulosic polysaccharides was the highest compared with all other cell wall sugars immediately after the pulse and decreased substantially during the subsequent chase. The relative radioactivities of the other cell wall sugars changedmore » with differing rates, indicating turnover of specific polysaccharides. Notably, after 1 month of chase there was a marked decrease in the proportional mass and total radioactivity in cell wall galactose, indicating a long-term turnover of the galactans enriched in the fiber-containing tissues. The ratio of radiolabeled xylose to arabinose also increased during the chase, indicating a turnover of arabinose-containing polymers and interconversion to xylose. The pattern of label redistribution differed between organs, indicating that the cell wall turnover processes are tissue- and cell-specific.« less

KC-135A in flight - closeup of winglet with attached tufts

NASA Technical Reports Server (NTRS)

1979-01-01

A chase plane view of the tufts on the KC-135 winglet. The use of tufts in flight research dates back to the early days of the NACA, and remains an effective means of observing airflow even today. In this procedure, rows of strings are attached to an airplane's surface, with one end of each string taped to the airplane and the other end free to swing about in the airflow. The movements of the tufts are photographed by on-board cameras or a chase plane. If the tufts are arrayed in neat rows, as seen here, then the airflow is smooth over the airplane's surface. If, however, they are moving about violently, it suggests turbulent airflow. Such motions may indicate high drag, flow separation (such as in a stall), or buffeting. In some cases, tufts will actually point forward, indicating the airflow has reversed direction.

NO2 DOAS Measurements of Traffic Emissions by Chasing Cars

NASA Astrophysics Data System (ADS)

Zhu, Ying; Lipkowitsch, Ivo; Chan, Ka Lok; Bräu, Melanie; Wenig, Mark

2016-04-01

On this poster we present NO2 measurements using a Cavity-Enhanced DOAS on a measurement bus which we used to chase other vehicles to measure their NO2 emissions. Emissions of nitrogen oxides from on-road vehicles have received highly attention recently due to the increasing trend of ambient NOx level. It is particularly important to identify and quantify the direct emission and secondary formation of NO2 contributed by traffic emissions, in order to study the impact to the local air quality. We sampled on-road emissions in different environments and different driving conditions (e.g. urban, highway, different speeds). We analyse the data set in terms of spatial and temporal variability to search for temporal and spatial patterns. We present mean values sorted for different vehicle types, distance to the target car and travelling speeds to provide an emission data base from this measurement study.

Does the obscured AGN fraction really depend on luminosity?

NASA Astrophysics Data System (ADS)

Sazonov, S.; Churazov, E.; Krivonos, R.

2015-12-01

We use a sample of 151 local non-blazar active galactic nuclei (AGN) selected from the INTEGRAL all-sky hard X-ray survey to investigate if the observed declining trend of the fraction of obscured (i.e. showing X-ray absorption) AGN with increasing luminosity is mostly an intrinsic or selection effect. Using a torus-obscuration model, we demonstrate that in addition to negative bias, due to absorption in the torus, in finding obscured AGN in hard X-ray flux-limited surveys, there is also positive bias in finding unobscured AGN, due to Compton reflection in the torus. These biases can be even stronger taking into account plausible intrinsic collimation of hard X-ray emission along the axis of the obscuring torus. Given the AGN luminosity function, which steepens at high luminosities, these observational biases lead to a decreasing observed fraction of obscured AGN with increasing luminosity even if this fraction has no intrinsic luminosity dependence. We find that if the central hard X-ray source in AGN is isotropic, the intrinsic (i.e. corrected for biases) obscured AGN fraction still shows a declining trend with luminosity, although the intrinsic obscured fraction is significantly larger than the observed one: the actual fraction is larger than ˜85 per cent at L ≲ 1042.5 erg s-1 (17-60 keV), and decreases to ≲60 per cent at L ≳ 1044 erg s-1. In terms of the half-opening angle θ of an obscuring torus, this implies that θ ≲ 30° in lower luminosity AGN, and θ ≳ 45° in higher luminosity ones. If, however, the emission from the central supermassive black hole is collimated as dL/dΩ ∝ cos α, the intrinsic dependence of the obscured AGN fraction is consistent with a luminosity-independent torus half-opening angle θ ˜ 30°.

White Hats Chasing Black Hats: Careers in IT and the Skills Required to Get There. Advisory from Professionals

ERIC Educational Resources Information Center

Fulton, Eric; Lawrence, Cameron; Clouse, Shawn

2013-01-01

The aim of this paper is to illuminate the exciting world in which "white hat crackers" operate and to suggest topics that can help prepare students to enter this high-demand field. While currently there is extraordinary demand for graduates to fill these positions that have relatively high starting salaries, employers find it difficult…

Eddington-limited Accretion in z ∼ 2 WISE-selected Hot, Dust-obscured Galaxies

NASA Astrophysics Data System (ADS)

Wu, Jingwen; Jun, Hyunsung D.; Assef, Roberto J.; Tsai, Chao-Wei; Wright, Edward L.; Eisenhardt, Peter R. M.; Blain, Andrew; Stern, Daniel; Díaz-Santos, Tanio; Denney, Kelly D.; Hayden, Brian T.; Perlmutter, Saul; Aldering, Greg; Boone, Kyle; Fagrelius, Parker

2018-01-01

Hot, dust-obscured galaxies, or “Hot DOGs,” are a rare, dusty, hyperluminous galaxy population discovered by the WISE mission. Predominantly at redshifts 2–3, they include the most luminous known galaxies in the universe. Their high luminosities likely come from accretion onto highly obscured supermassive black holes (SMBHs). We have conducted a pilot survey to measure the SMBH masses of five z∼ 2 Hot DOGs via broad Hα emission lines, using Keck/MOSFIRE and Gemini/FLAMINGOS-2. We detect broad Hα emission in all five Hot DOGs. We find substantial corresponding SMBH masses for these Hot DOGs (∼ {10}9 {M}ȯ ), and their derived Eddington ratios are close to unity. These z∼ 2 Hot DOGs are the most luminous active galactic nuclei for their BH masses, suggesting that they are accreting at the maximum rates for their BHs. A similar property is found for known z∼ 6 quasars. Our results are consistent with scenarios in which Hot DOGs represent a transitional, high-accretion phase between obscured and unobscured quasars. Hot DOGs may mark a special evolutionary stage before the red quasar and optical quasar phases, and they may be present at other cosmic epochs.

Effects of water level changes and wading bird abundance on the foraging behaviour of blacknecked storks Ephippiorhynchus asiaticus in Dudwa National Park, India.

PubMed

Maheswaran, G; Rahmani, A R

2001-09-01

The effect of water level changes and wading birds' abundance on the foraging behaviour of the blacknecked stork (BNS) Ephippiorhynchus asiaticus was studied from January 1995 to June 1997 in Dudwa National Park, Uttar Pradesh. Our observations indicate that BNS territoriality increased as food levels became depleted, resulting in increased rates of aggression towards intruders. Chasing or aggression was more intense during the early period (February and March) than the late period (April, May and June). Most of (> 50%) the aggressive encounters were observed between 0600 and 1000 h of the day. Seventeen species (including BNS) were observed interacting with BNS, throughout the study period. Most interactions were with the spoonbill, Platalea leucorodia (67.4%), followed by the whitenecked stork, Ciconia episcopus (16.6%). The distance (while foraging) between BNS and other wading birds varied significantly (P < 0.001) between years indicating that BNS and other water birds foraged at different water depths and thereby explored the wetlands fully. Spoonbills were chased often; the number varied from 1 to 43 birds. BNS occasionally accepted the presence of other wading birds, including spoonbills and started foraging amidst them. This led to successful foraging of BNS (solitary feeder). Other fish-eating bird species and their numbers also limited the food consumption of foraging BNS as they had to spend time chasing away the intruders. Availability of the preferred prey fish species, Heteropnestus fossilis, forced BNS to stay throughout the year in their respective territories. High (> 60 cm) water levels were not suitable for BNS even though the patch had high prey abundance.

Flamingos 2 Spectroscopy of Obscured and Unobscured Quasars

NASA Astrophysics Data System (ADS)

Ridgway, Susan; Lacy, Mark; Urrutia, Tanya; Petric, Andreea

2013-08-01

We will use Flamingos-2 to obtain spectra of luminous AGN and quasars selected in the mid-infrared. Mid-infrared selection is much less biased with respect to obscuration than optical and X-ray techniques, and hence allows for finding obscured (Type-2) quasars as well as Type-1 quasars. Our survey so far has been very successful and has provided an unique opportunity to construct luminosity functions for both Type-1 and Type-2 quasars selected in the same way and covering similar redshifts and luminosities. We have quantifed the change in the obscured fraction with luminosity and redshift for the first time, and find interesting indications that at high redshift the obscured fraction rises, consistent with models for the joint formation of the galaxy and black hole populations. Our samples are, however, still quite incomplete at low fluxes (and therefore lower luminosities at a given redshift), particularly in the southern hemisphere. Near-infrared spectroscopy, such as that we have previously obtained with NIRI at Gemini N, offers us the best possibility of bringing these southern samples to a reasonable completeness level, and will greatly increase the number of high z quasars in our sample. This will allow us to better judge our tantalizing initial results on the redshift evolution of the obscured fraction. In addition, these southern targets can be followed up with ALMA and GEMS/GSAOI to study the morphologies and star-formation properties of the hosts, allowing further exploration of the relationship between the formation of massive bulges and supermassive blackholes in the early universe.

Chasing the College Dream in Hard Economic Times. Issue Brief

ERIC Educational Resources Information Center

Buddin, Richard; Croft, Michelle

2014-01-01

Slow economic growth in the past several years has strained the financial resources of many American families and heightened financial burdens for families hoping to support their children's college education. These economic struggles come at a critical time for high school students who rely on family resources to fund large portions of college…

The Guardians Initiative: A Student-Centered Approach to Bullying

ERIC Educational Resources Information Center

Toledo, Gregory

2008-01-01

Something wicked is being chased out of the classrooms and hallways at a high school in Massachusetts, something prevalent in schools across the globe: bullying. For generations, victims have carried invisible scars or nursed open wounds. Concerns related to bullying have been confirmed by extensive research over the past decade, including…

History Run Wild: The Alternate World of Joan Aiken's "The Wolves of Willoughby Chase" Series

ERIC Educational Resources Information Center

Dams, Isobel

2005-01-01

This article examines the historical fantasy world created by Joan Aiken in the eleven volumes of her "Wolves of Willoughby Chase" series. In particular it looks at her subversion of historical reality by the creation of an alternative yet recognisable representation of our own world, using a wide range of events, and the remoulding of aspects of…

The Effect of Laziness in Group Chase and Escape

NASA Astrophysics Data System (ADS)

Masuko, Makoto; Hiraoka, Takayuki; Ito, Nobuyasu; Shimada, Takashi

2017-08-01

The effect of laziness in the group chase and escape problem is studied using a simple model. Laziness is introduced as random walks in two ways: uniformly and in a "division of labor" way. It is shown that while the former is always ineffective, the latter can improve the efficiency of catching, through the formation of pincer attack configuration by diligent and lazy chasers.

Structures of the Oligosaccharides of the Glycoprotein Coded by Early Region E3 of Adenovirus 2

PubMed Central

Kornfeld, Rosalind; Wold, William S. M.

1981-01-01

Early region E3 of adenovirus 2 encodes a glycoprotein, E3-gp25K, that is a good model with which to study structure-function relationships in transmembrane glycoproteins. We have determined the structures of the oligosaccharides linked to E3-gp25K. The oligosaccharides were labeled with [2-3H]mannose in adenovirus 2-early infected KB cells for 5.5h (pulse) or for 5.5 h followed by a 3-h chase (pulse-chase). E3-gp25K was extracted and purified by chromatography on DEAE-Sephacel in 7 M urea, followed by gel filtration on a column of Bio-Gel A-1.5m in 6 M guanidine hydrochloride. An analysis of the purified protein by sodium dodecyl sulfate-polyacrylamide gel electrophoresis indicated that it was >95% pure. The oligosaccharides were isolated by pronase digestion followed by gel filtration on a column of Bio-Gel P-6, then by digestion with endo-β-N-acetylglucosaminidase H, followed by gel filtration on Bio-Gel P-6, and finally by paper chromatography. The pulse sample contained equal amounts of Man9GlcNAc and Man8GlcNAc and small amounts of Man7GlcNAc and Man6GlcNAc. The pulse-chase sample had predominantly Man8GlcNAc and much less Man9GlcNAc, indicating that processing of the Man9GlcNAc to Man8GlcNAc had occurred during the chase period. Thus, Man8GlcNAc is the major oligosaccharide on mature E3-gp25K. The structures of these oligosaccharides were established by digestion with α-mannosidase, methylation analysis, and acetolysis. The oligosaccharides found had typical high-mannose structures that have been observed in other membrane and soluble glycoproteins, and the branching patterns and linkages of the mannose residues of Man9GlcNAc were identical to those of the lipid-linked Glc3Man9GlcNAc2 donor. Thus, adenovirus 2 infection (early stages) apparently does not affect the usual cellular high-mannose glycosylation pathways, and despite being virus coded, E3-gp25K is glycosylated in the same manner as a typical mammalian cell-coded glycoprotein. Images PMID:7321093

Structures of the oligosaccharides of the glycoprotein coded by early region E3 of adenovirus 2.

PubMed

Kornfeld, R; Wold, W S

1981-11-01

Early region E3 of adenovirus 2 encodes a glycoprotein, E3-gp25K, that is a good model with which to study structure-function relationships in transmembrane glycoproteins. We have determined the structures of the oligosaccharides linked to E3-gp25K. The oligosaccharides were labeled with [2-(3)H]mannose in adenovirus 2-early infected KB cells for 5.5h (pulse) or for 5.5 h followed by a 3-h chase (pulse-chase). E3-gp25K was extracted and purified by chromatography on DEAE-Sephacel in 7 M urea, followed by gel filtration on a column of Bio-Gel A-1.5m in 6 M guanidine hydrochloride. An analysis of the purified protein by sodium dodecyl sulfate-polyacrylamide gel electrophoresis indicated that it was >95% pure. The oligosaccharides were isolated by pronase digestion followed by gel filtration on a column of Bio-Gel P-6, then by digestion with endo-beta-N-acetylglucosaminidase H, followed by gel filtration on Bio-Gel P-6, and finally by paper chromatography. The pulse sample contained equal amounts of Man(9)GlcNAc and Man(8)GlcNAc and small amounts of Man(7)GlcNAc and Man(6)GlcNAc. The pulse-chase sample had predominantly Man(8)GlcNAc and much less Man(9)GlcNAc, indicating that processing of the Man(9)GlcNAc to Man(8)GlcNAc had occurred during the chase period. Thus, Man(8)GlcNAc is the major oligosaccharide on mature E3-gp25K. The structures of these oligosaccharides were established by digestion with alpha-mannosidase, methylation analysis, and acetolysis. The oligosaccharides found had typical high-mannose structures that have been observed in other membrane and soluble glycoproteins, and the branching patterns and linkages of the mannose residues of Man(9)GlcNAc were identical to those of the lipid-linked Glc(3)Man(9)GlcNAc(2) donor. Thus, adenovirus 2 infection (early stages) apparently does not affect the usual cellular high-mannose glycosylation pathways, and despite being virus coded, E3-gp25K is glycosylated in the same manner as a typical mammalian cell-coded glycoprotein.

Can dryland geoproxy data generate Quaternary palaeoclimate and palaeoenvironmental records?

NASA Astrophysics Data System (ADS)

Thomas, David S. G.

2017-04-01

Dryland regions present many challenges for robustly reconstructing late Quaternary palaeoenvironments and palaeoclimates, not least a common deficit, or considerable spatial variability, in the availability of high resolution biological proxy data sources. Substantial advances have been made in some regions in recent years, through the exploitation of new high resolution biomarker and isotope records, for example from hyrax middens (e.g. Chase et al., 2012) and from offshore sediments (e.g. Collins et al., 2014). In others however, suitable data sources for these approaches are absent, so these approaches are not available or if data are applied from distant sources, subject to risks of excessive spatial extrapolation of records in environmental contexts where environmental gradients are steep and variability is common (Thomas and Burrough, 2012, Thomas et al., 2013). In these contexts, geoproxy records, derived from the analysis of landforms and their associated sediments, are often utilised in dryland Quaternary research (e.g. Burrough and Thomas 2009, Stone and Thomas, 2013, Thomas, 2013, Lancaster et al., 2015), but with a number of associated difficulties (e.g. Chase, 2009). This paper examines these difficulties and then explores different approaches to the analysis of Quaternary landform records. It is argued that geoproxies with chronometric control, usually provided by OSL dating, have considerable potential to improve data on Quaternary environmental and climate dynamics, if records are interpreted effectively and appropriately (e.g. Bailey and Thomas, 2014, Thomas and Burrough, 2016). Examples of challenges and new approaches will be drawn from aeolian and fluvial domains, and from research in Africa, Australia and Arabia. Bailey RM, Thomas DSG 2014 Earth Surf. Proc. Landf. 39, 614-631. Burrough SL, Thomas DSG 2009. Geomorphology 103, 285-298. Chase, B 2009. Earth-Sci Rev. 93, 31-45. Chase BM et al. 2010 Quat. Sci. Rev. 56, 107-125. Collins JA et al. 2014 Earth Planet. Sci. Let. 398, 1-10. Lancaster N et al. 2016 Quat. Int. 410, 3-10. Stone AEC, Thomas DSG 2013 J. Arid Env. 93, 40-58. Thomas DSG 2013 Earth Surf. Proc. Landf. 38, 3-16. Thomas DSG, Burrough SL 2012 Quat. Int. 253, 5-17. Thomas DSG et al. 2012 J. Quat. Sci. 27, 7-12. Thomas DSG, Burrough SL 2016 Quat. Int. 410, 30-45.

Following isotopes in pulse-chase enriched aspen seedlings

NASA Astrophysics Data System (ADS)

Norris, C. E.; Wasylishen, R. E.; Landhäusser, S.; Quideau, S. A.

2011-12-01

One method to quantitatively trace biogeochemical fluxes through ecosystems, such as organic matter decomposition, is to use plant material enriched with stable isotopes. However, as plant macromolecules are known to vary in their rate of formation and decomposition, both the enrichment levels and the location of enrichment within the plant material should be characterized prior to decomposition and tracing studies. Aspen (Populus tremuloides Michx.) is a common tree species with a diverse organic matter chemical structure found in the western Canadian boreal forest. This study used a multi pulse and multi chase enrichment of stable isotopes (15N and 13C) on aspen seedlings to determine the seedling enrichment, isotope movement among plant tissues and translocation of isotopes within plant macromolecules e.g., carbohydrates and lignin. As expected, all tissues experienced increased enrichment with multiple pulses. An initial enrichment with 13C was observed in the leaves followed by translocation to the stems and roots while the 15N moved upward from the roots to leaves. The macromolecular chemistry of the organic carbon was further characterized using 13C solid state nuclear magnetic resonance spectroscopy. After the initial two hour chase period enrichment of the O-alkyl type (carbohydrate) carbon within the leaves was identified, followed by redistribution to more complex carbon compounds after the one week chase period. Root and stem tissues did not show the same pattern. Rather, changes in 13C enrichment were observed in shifting ethyl and methyl alkyl (lipid) carbon peak intensities for the stem samples while roots did not preferentially allocate 13C to a specific macromolecule. These results confirm that stable isotope enrichment of plants was non-uniform across macromolecules and tissue types. Enrichment of aspen seedlings was therefore dependant on the pulse-chase sequence used.

The Language of Medicine: The Ethics of Obscurity.

ERIC Educational Resources Information Center

Jolly, Peggy

Because physicians are perceived as powerful and knowledgeable professionals, the language they use to address patients has a tremendous effect on a patient's mental and physical well-being. Physicians often speak to patients in "med-speak," obscure, highly technical terms that cloak the reality of the patient's condition and serve to reinforce…

The ionization cone, obscured nucleus, and gaseous outflow in NGC 3281 - A prototypical Seyfert 2 galaxy?

NASA Technical Reports Server (NTRS)

Storchi-Bergmann, Thaisa; Wilson, Andrew S.; Baldwin, Jack A.

1992-01-01

Narrow-band images and long-slit spectroscopy of the central region of the highly inclined Seyfert galaxy NGC 3281 are presented. The image of the continuum-subtracted forbidden 4959 emission line shows a very clear conical morphology for the high-excitation gas. A possible similar structure can also be seen on the other side of the nucleus, but is dimmed by patchy obscuration in the dusk. The continuum images and long-slit spectroscopy are used to derive and map the extinction in the inner regions of NGC 3281; heavy obscuration is found along the present line of sight to the apex of the cone, suggesting that the true nucleus is located at the apex and is obscured. Low-resolution long-slit spectra are used to study the stellar population, which is found to be old, uniform within 2.5 kpc of the nucleus, and typical of the bulges of early-type galaxies. It is suggested that NGC3281 may be another example of a 'hidden' Seyfert 1, even though there is no direct evidence for a broad-line region in this particular galaxy.

Intracellular synthesis, processing, and transport of proteins encoded by ORFs 5 to 7 of porcine reproductive and respiratory syndrome virus.

PubMed

Mardassi, H; Massie, B; Dea, S

1996-07-01

Porcine Reproductive and Respiratory Syndrome Virus (PRRSV), a small enveloped virus containing a positive-strand RNA genome, possesses at least three major structural proteins designated N, M, and E. The N protein is considered as the major component of the nucleocapsid, whereas M and E are membrane-associated. Previous studies using peptide-specific antibodies assigned these proteins to ORFs 7, 6, and 5, respectively. In the present report, monospecific antisera raised against Escherichia coli-expressed ORFs 5, 6, and 7 products were used to study the synthesis and processing of PRRSV structural proteins in the highly permissive MARC-145 cell line. Treatment of viral proteins with various glycosidases showed that only E was modified by N-linked glycans. Pulse-chase experiments revealed that intracellular transport of the major envelope glycoprotein was delayed in the premedial Golgi compartment. During the first 30 min of chase, E undergoes a gradual downward shift of its apparent molecular weight, thought to result from trimming of the mannose-rich glycan structures. Once E is transported to the medial Golgi or proximal elements, some molecules undergo complete processing of all their high-mannose N-linked oligosaccharides to complex type, while in other molecules only a fraction of N-linked glycans are terminally glycosylated. These two differentially glycosylated forms of E were found to be incorporated into extracellular virions. In cells and virions, both M and E were shown to occur in heterodimeric complexes linked by disulfide bonds. The oligomerization process, as analyzed from pulse-chase experiments, showed that M and E are incorporated into M-E complexes with different kinetics and efficiencies, in a fashion similar to their counterparts in equine arteritis virus. Apparently, all steps of E protein N-glycans processing proceed after its association with M which occurs in the endoplasmic reticulum (ER). In the infected cells, E and M appear highly membrane-associated, while N is predominantly cytosolic.

Cheetah do not abandon hunts because they overheat.

PubMed

Hetem, Robyn S; Mitchell, Duncan; de Witt, Brenda A; Fick, Linda G; Meyer, Leith C R; Maloney, Shane K; Fuller, Andrea

2013-10-23

Hunting cheetah reportedly store metabolic heat during the chase and abandon chases because they overheat. Using biologging to remotely measure the body temperature (every minute) and locomotor activity (every 5 min) of four free-living cheetah, hunting spontaneously, we found that cheetah abandoned hunts, but not because they overheated. Body temperature averaged 38.4°C when the chase was terminated. Storage of metabolic heat did not compromise hunts. The increase in body temperature following a successful hunt was double that of an unsuccessful hunt (1.3°C ± 0.2°C versus 0.5°C ± 0.1°C), even though the level of activity during the hunts was similar. We propose that the increase in body temperature following a successful hunt is a stress hyperthermia, rather than an exercise-induced hyperthermia.

Cheetah do not abandon hunts because they overheat

PubMed Central

Hetem, Robyn S.; Mitchell, Duncan; de Witt, Brenda A.; Fick, Linda G.; Meyer, Leith C. R.; Maloney, Shane K.; Fuller, Andrea

2013-01-01

Hunting cheetah reportedly store metabolic heat during the chase and abandon chases because they overheat. Using biologging to remotely measure the body temperature (every minute) and locomotor activity (every 5 min) of four free-living cheetah, hunting spontaneously, we found that cheetah abandoned hunts, but not because they overheated. Body temperature averaged 38.4°C when the chase was terminated. Storage of metabolic heat did not compromise hunts. The increase in body temperature following a successful hunt was double that of an unsuccessful hunt (1.3°C ± 0.2°C versus 0.5°C ± 0.1°C), even though the level of activity during the hunts was similar. We propose that the increase in body temperature following a successful hunt is a stress hyperthermia, rather than an exercise-induced hyperthermia. PMID:23883578

AGARD Conference Proceedings on High Resolution Air and Spaceborne Radar Held in The Hague, Netherlands on 8-12 May 1989

DTIC Science & Technology

1989-05-01

swat~h widt-h cncd resolutirun 111I 121. A number -if lu,o,. tt, tray I, ii- ccut ii-,- Il related to the use? of active (chased arraysi - Elect ronic...Address Pax ’ues Various 230 12.tlltrtutt~n tetmon This document is distributed in accordanc with NATIO Security Regulations and A0ARI) policies . High

X-Ray Spectral Properties of Seven Heavily Obscured Seyfert 2 Galaxies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Marchesi, S.; Ajello, M.; Comastri, A.

2017-02-10

We present the combined Chandra and Swift -BAT spectral analysis of seven Seyfert 2 galaxies selected from the Swift -BAT 100 month catalog. We selected nearby ( z ≤ 0.03) sources lacking a ROSAT counterpart that never previously been observed with Chandra in the 0.3–10 keV energy range, and targeted these objects with 10 ks Chandra ACIS-S observations. The X-ray spectral fitting over the 0.3–150 keV energy range allows us to determine that all the objects are significantly obscured, with N{sub H} ≥ 10{sup 23} cm{sup −2} at a >99% confidence level. Moreover, one to three sources are candidate Compton-thickmore » Active Galactic Nuclei (CT-AGNs; i.e., N{sub H}≥10{sup 24} cm{sup −2}). We also test the recent spectral curvature method developed by Koss et al. to find candidate CT-AGNs, finding a good agreement between our results and their predictions. Because the selection criteria we adopted were effective in detecting highly obscured AGNs, further observations of these and other Seyfert 2 galaxies selected from the Swift -BAT 100 month catalog will allow us to create a statistically significant sample of highly obscured AGNs, therefore providing a better understanding of the physics of the obscuration processes.« less

IC 3639—a New Bona Fide Compton-Thick AGN Unveiled by NuSTAR

NASA Astrophysics Data System (ADS)

Boorman, Peter G.; Gandhi, P.; Alexander, D. M.; Annuar, A.; Ballantyne, D. R.; Bauer, F.; Boggs, S. E.; Brandt, W. N.; Brightman, M.; Christensen, F. E.; Craig, W. W.; Farrah, D.; Hailey, C. J.; Harrison, F. A.; Hönig, S. F.; Koss, M.; LaMassa, S. M.; Masini, A.; Ricci, C.; Risaliti, G.; Stern, D.; Zhang, W. W.

2016-12-01

We analyze high-quality NuSTAR observations of the local (z = 0.011) Seyfert 2 active galactic nucleus (AGN) IC 3639, in conjunction with archival Suzaku and Chandra data. This provides the first broadband X-ray spectral analysis of the source, spanning nearly two decades in energy (0.5-30 keV). Previous X-ray observations of the source below 10 keV indicated strong reflection/obscuration on the basis of a pronounced iron fluorescence line at 6.4 keV. The hard X-ray energy coverage of NuSTAR, together with self-consistent toroidal reprocessing models, enables direct broadband constraints on the obscuring column density of the source. We find the source to be heavily Compton-thick (CTK) with an obscuring column in excess of 3.6× {10}24 cm-2, unconstrained at the upper end. We further find an intrinsic 2-10 keV luminosity of {{log}}10({L}2{--10{keV}} [{erg} {{{s}}}-1])={43.4}-1.1+0.6 to 90% confidence, almost 400 times the observed flux, and consistent with various multiwavelength diagnostics. Such a high ratio of intrinsic to observed flux, in addition to an Fe-Kα fluorescence line equivalent width exceeding 2 keV, is extreme among known bona fide CTK AGNs, which we suggest are both due to the high level of obscuration present around IC 3639. Our study demonstrates that broadband spectroscopic modeling with NuSTAR enables large corrections for obscuration to be carried out robustly and emphasizes the need for improved modeling of AGN tori showing intense iron fluorescence.

Evidence for carboxyl-terminal processing and glycolipid-anchoring of human carcinoembryonic antigen.

PubMed

Takami, N; Misumi, Y; Kuroki, M; Matsuoka, Y; Ikehara, Y

1988-09-05

We have investigated the post-translational modification of carcinoembryonic antigen (CEA) for membrane-anchoring in QGP-1 cells derived from a human pancreatic carcinoma. Pulse-chase experiments with [3H]leucine demonstrated that CEA was initially synthesized as a precursor form with Mr 150,000 having N-linked high-mannose-type oligosaccharides, which was then converted to a mature form with Mr 200,000 containing the complex type sugar chains. The mature protein thus labeled was found to be released from the cell surface by treatment with phosphatidylinositol-specific phospholipase C, suggesting that CEA is a phosphatidylinositol-linked membrane protein. This was confirmed by metabolic incorporation into CEA of 3H-labeled compounds such as ethanolamine, myo-inositol, palmitic acid, and stearic acid. The 3H-labeled fatty acids incorporated were specifically removed from the protein by nitrous acid deamination as well as by phosphatidylinositol-specific phospholipase C treatment. Since the available cDNA sequence predicts that CEA contains a single methionine residue only in its carboxyl-terminal hydrophobic domain, processing of the carboxyl terminus was examined by pulse-chase experiments with [35S]methionine. It was found that CEA with Mr 150,000 was initially labeled with [35S]methionine but its radioactivity was immediately lost with chase. Taken together, these results suggest that CEA is anchored to the membrane by simultaneously occurring proteolysis of the carboxyl terminus and replacement by the glycophospholipid immediately after the synthesis.

ALMA Detections of CO Emission in the Most Luminous, Heavily Dust-obscured Quasars at z > 3

NASA Astrophysics Data System (ADS)

Fan, Lulu; Knudsen, Kirsten K.; Fogasy, Judit; Drouart, Guillaume

2018-03-01

We report the results of a pilot study of CO(4 ‑ 3) emission line of three Wide-field Infrared Survey Explorer (WISE)-selected hyper-luminous, dust-obscured quasars (QSOs) with sensitive ALMA Band 3 observations. These obscured QSOs with L bol > 1014 L ⊙ are among the most luminous objects in the universe. All three QSO hosts are clearly detected both in continuum and in CO(4 ‑ 3) emission line. Based on CO(4 ‑ 3) emission line detection, we derive the molecular gas masses (∼1010‑11 M ⊙), suggesting that these QSOs are gas-rich systems. We find that the obscured QSOs in our sample follow the similar {L}CO}{\\prime }{--}{L}FIR} relation as unobscured QSOs at high redshifts. We also find the complex velocity structures of CO(4 ‑ 3) emission line, which provide the possible evidence for a gas-rich merger in W0149+2350 and possible molecular outflow in W0220+0137 and W0410‑0913. Massive molecular outflow can blow away the obscured interstellar medium and make obscured QSOs evolve toward the UV/optical bright, unobscured phase. Our result is consistent with the popular active galactic nucleus (AGN) feedback scenario involving the co-evolution between the supermassive black holes and host galaxy.

Douglas Lowy and Nirali Shah discuss advancements in cancer treatment at the second annual Chasing Cancer Summit | Center for Cancer Research

Cancer.gov

On Monday, September 18, 2017, the second annual Chasing Cancer Summit was held at the Washington Post headquarters in downtown Washington, D.C. The live event brought together a group of experts, including CCR’s Douglas Lowy, M.D., and Nirali Shah, M.D., for discussions on the latest developments in cancer detection and treatment.  Read more...

The influence of complex and threatening environments in early life on brain size and behaviour.

PubMed

DePasquale, C; Neuberger, T; Hirrlinger, A M; Braithwaite, V A

2016-01-27

The ways in which challenging environments during development shape the brain and behaviour are increasingly being addressed. To date, studies typically consider only single variables, but the real world is more complex. Many factors simultaneously affect the brain and behaviour, and whether these work independently or interact remains untested. To address this, zebrafish (Danio rerio) were reared in a two-by-two design in housing that varied in structural complexity and/or exposure to a stressor. Fish experiencing both complexity (enrichment objects changed over time) and mild stress (daily net chasing) exhibited enhanced learning and were less anxious when tested as juveniles (between 77 and 90 days). Adults tested (aged 1 year) were also less anxious even though fish were kept in standard housing after three months of age (i.e. no chasing or enrichment). Volumetric measures of the brain using magnetic resonance imaging (MRI) showed that complexity alone generated fish with a larger brain, but this increase in size was not seen in fish that experienced both complexity and chasing, or chasing alone. The results highlight the importance of looking at multiple variables simultaneously, and reveal differential effects of complexity and stressful experiences during development of the brain and behaviour. © 2016 The Authors.

The influence of complex and threatening environments in early life on brain size and behaviour

PubMed Central

Neuberger, T.; Hirrlinger, A. M.; Braithwaite, V. A.

2016-01-01

The ways in which challenging environments during development shape the brain and behaviour are increasingly being addressed. To date, studies typically consider only single variables, but the real world is more complex. Many factors simultaneously affect the brain and behaviour, and whether these work independently or interact remains untested. To address this, zebrafish (Danio rerio) were reared in a two-by-two design in housing that varied in structural complexity and/or exposure to a stressor. Fish experiencing both complexity (enrichment objects changed over time) and mild stress (daily net chasing) exhibited enhanced learning and were less anxious when tested as juveniles (between 77 and 90 days). Adults tested (aged 1 year) were also less anxious even though fish were kept in standard housing after three months of age (i.e. no chasing or enrichment). Volumetric measures of the brain using magnetic resonance imaging (MRI) showed that complexity alone generated fish with a larger brain, but this increase in size was not seen in fish that experienced both complexity and chasing, or chasing alone. The results highlight the importance of looking at multiple variables simultaneously, and reveal differential effects of complexity and stressful experiences during development of the brain and behaviour. PMID:26817780

THE OBSCURED FRACTION OF ACTIVE GALACTIC NUCLEI IN THE XMM-COSMOS SURVEY: A SPECTRAL ENERGY DISTRIBUTION PERSPECTIVE

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lusso, E.; Hennawi, J. F.; Richards, G. T.

2013-11-10

The fraction of active galactic nucleus (AGN) luminosity obscured by dust and re-emitted in the mid-IR is critical for understanding AGN evolution, unification, and parsec-scale AGN physics. For unobscured (Type 1) AGNs, where we have a direct view of the accretion disk, the dust covering factor can be measured by computing the ratio of re-processed mid-IR emission to intrinsic nuclear bolometric luminosity. We use this technique to estimate the obscured AGN fraction as a function of luminosity and redshift for 513 Type 1 AGNs from the XMM-COSMOS survey. The re-processed and intrinsic luminosities are computed by fitting the 18 bandmore » COSMOS photometry with a custom spectral energy distribution fitting code, which jointly models emission from hot dust in the AGN torus, from the accretion disk, and from the host galaxy. We find a relatively shallow decrease of the luminosity ratio as a function of L{sub bol}, which we interpret as a corresponding decrease in the obscured fraction. In the context of the receding torus model, where dust sublimation reduces the covering factor of more luminous AGNs, our measurements require a torus height that increases with luminosity as h ∝ L{sub bol}{sup 0.3-0.4}. Our obscured-fraction-luminosity relation agrees with determinations from Sloan Digital Sky Survey censuses of Type 1 and Type 2 quasars and favors a torus optically thin to mid-IR radiation. We find a much weaker dependence of the obscured fraction on 2-10 keV luminosity than previous determinations from X-ray surveys and argue that X-ray surveys miss a significant population of highly obscured Compton-thick AGNs. Our analysis shows no clear evidence for evolution of the obscured fraction with redshift.« less

AGN radiative feedback in dusty quasar populations

NASA Astrophysics Data System (ADS)

Ishibashi, W.; Banerji, M.; Fabian, A. C.

2017-08-01

New populations of hyper-luminous, dust-obscured quasars have been recently discovered around the peak epoch of galaxy formation (z ˜ 2-3), in addition to similar sources found at lower redshifts. Such dusty quasars are often interpreted as sources 'in transition', from dust-enshrouded starbursts to unobscured luminous quasars, along the evolutionary sequence. Here we consider the role of the active galactic nucleus (AGN) radiative feedback, driven by radiation pressure on dust, in high-luminosity, dust-obscured sources. We analyse how the radiation pressure-driven dusty shell models, with different shell mass configurations, may be applied to the different populations of dusty quasars reported in recent observations. We find that expanding shells, sweeping up matter from the surrounding environment, may account for prolonged obscuration in dusty quasars, e.g. for a central luminosity of L ˜ 1047 erg s-1, a typical obscured phase (with extinction in the range AV ˜ 1-10 mag) may last a few ˜106 yr. On the other hand, fixed-mass shells, coupled with high dust-to-gas ratios, may explain the extreme outflows recently discovered in red quasars at high redshifts. We discuss how the interaction between AGN radiative feedback and the ambient medium at different temporal stages in the evolutionary sequence may contribute to shape the observational appearance of dusty quasar populations.

The Environments of Obscured Quasars

NASA Astrophysics Data System (ADS)

Jones, Kristen M.; Lacy, Mark; Nielsen, Danielle

2016-01-01

Supermassive Black Hole (SMBH) feedback is prescribed for driving the high-end shape of the galaxy luminosity function, clearing the circumnuclear environment during the end stages of mergers, and eventually turning off its own accretion. Yet the dominant processes and characteristics of active galactic nuclei are indistinct. Chief among this confusion is how significant the role of dust is in each galaxy. Orientation of the dusty torus is attributed to causing the differences between Sy1 and Sy2, but whether obscured quasars are found in particularly dusty host galaxies, if they exist at a different stage in the merger process (early on, before the dust is blown out), or if they are merely oriented differently than optical quasars is not yet so well distinguished. With obscured quasars now observed to make up 50% or greater of the population of quasars, the question of what causes obscuration becomes vital to address. With this in mind, I study matched samples of obscured and unobscured quasars to characterize their environments, with the intent of addressing what contribution environment has to obscuration levels. I investigate the megaparsec-scale environments of SIRTF Wide-field Infra-Red Extragalactic Survey (SWIRE) quasars at z ˜ 1-3 by cross-correlating the sample with 3.8 million galaxies from the Spitzer Extragalactic Representative Volume Survey (SERVS). Optically obscured quasars are compared to a control sample of optically-bright quasars via selection in the mid-infrared. Environments were observed at 3.6 and 4.5 μm to a depth of ≈ 2 μJy (AB = 23.1). Recent work has found diverse results in such studies, with dependence of environmental richness on both redshift and level of obscuration. I find that, within reasonable error, on average there is no distinct difference between the level of clustering for obscured and normal quasars, and that there is no dependence on redshift of this result within the range of 1.3 < z < 2.5. I compare our results with recent studies and investigate the role of selection criteria in the assessment of clustering. I also explore the large scale SED structure of obscured and unobscured quasar host galaxies.

The Speeding Car Design Challenge

ERIC Educational Resources Information Center

Roman, Harry T.

2009-01-01

All too often, one reads about high-speed police chases in pursuit of stolen cars that result in death and injury to people and innocent bystanders. Isn't there another way to accomplish the apprehension of the thieves that does not put people at such great risk? This article presents a classroom challenge to use technology to remotely shutdown…

E-1152

NASA Image and Video Library

1954-01-17

These people and this equipment supported the flight of the NACA D-558-2 Skyrocket at the High-Speed Flight Station at South Base, Edwards AFB. Note the two Sabre chase planes, the P2B-1S launch aircraft, and the profusion of ground support equipment, including communications, tracking, maintenance, and rescue vehicles. Research pilot A. Scott Crossfield stands in front of the Skyrocket.

Fox Chase Cancer Center's Genitourinary Division: a national resource for research, innovation and patient care.

PubMed

Uzzo, Robert G; Horwitz, Eric M; Plimack, Elizabeth R

2016-04-01

Founded in 1904, Fox Chase Cancer Center remains committed to its mission. It is one of 41 centers in the country designated as a Comprehensive Cancer Center by the National Cancer Institute, is a founding member of the National Comprehensive Cancer Network, holds the magnet designation for nursing excellence, is one of the first to establish a family cancer risk assessment program, and has achieved national distinction because of the scientific discoveries made there that have advanced clinical care. Two of its researchers have won Nobel prizes. The Genitourinary Division is nationally recognized and viewed as one of the top driving forces behind the growth of Fox Chase due to its commitment to initiating and participating in clinical trials, its prolific contributions to peer-reviewed publications and presentations at scientific meetings, its innovations in therapies and treatment strategies, and its commitment to bringing cutting-edge therapies to patients.

A Factor Increasing Venous Contamination on Bolus Chase Three-dimensional Magnetic Resonance Imaging: Charcot Neuroarthropathy.

PubMed

Çildağ, Mehmet B; Ertuğrul, Mustafa B; Köseoğlu, Ömer Fk; Armstrong, David G

2018-01-01

The study aimed to evaluate the ratio of venous contamination in diabetic cases without foot lesion, with foot lesion and with Charcot neuroarthropathy (CN). Bolus-chase three-dimensional magnetic resonance (MR) of 396 extremities of patients with diabetes mellitus was analyzed, retrospectively. Extremities were divided into three groups as follows: diabetic patients without foot ulcer or Charcot arthropathy (Group A), patients with diabetic foot ulcers (Group B) and patients with CN accompanying diabetic foot ulcers (Group C). Furthermore, amount of venous contamination classified as no venous contamination, mild venous contamination, and severe venous contamination. The relationship between venous contamination and extremity groups was investigated. Severe venous contamination was seen in Group A, Group B, and Group C, 5.6%, 15.2%, and 34.1%, respectively. Statistically significant difference was seen between groups with regard to venous contamination. Venous contamination following bolus chase MR was higher in patients with CN.

STS-4 landing at Edwards Air Foce Base, California

NASA Technical Reports Server (NTRS)

1982-01-01

STS-4 landing at Edwards Air Foce Base, California. Actor Roy Rogers with Astronauts Jerry L. Ross, left, and Guy S. Gardner at Edwards for the STS-4 landing on July 1, 1982. Also present (behind Gardner at extreme right) was former Astronaut Edwin E. Aldrin, Jr. (33226); President Ronald Reagan and First Lady Nancy Reagan meet Astronauts Thomas K. Mattingly, II., right, and Henry W. Hartsfield, Jr., after the landing of the Columbia at Edwards (33227,33230); Space Shuttle Columbia, followed by two T-38 chase planes, touches down on Edwards Air Force Base's Runway 22 to complete mission. In this view, one chase plane appears to be directly above and behind the Columbia, whose nose wheels have not yet touched ground. The other plane appears to be further up front (33228); The rear wheels of the Columbia touch down on the Edwards AFB runway. There are no chase planes in sight in this photo (33229).

Technology Solutions Case Study: Duct in Conditioned Space in a Dropped Ceiling or Fur-down, Gainesville, Florida

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

2014-09-01

Forced-air distribution systems (duct systems) typically are installed out of sight for aesthetic reasons, most often in unconditioned areas such as attics or crawlspaces. Any leakage of air to or from the duct system in unconditioned space not only loses energy, but impacts home and equipment durability and indoor air quality. An obvious solution is to bring the duct system into the interior of the house, either by sealing the area where the ducts are installed (attic or crawlspace) or by building an interior cavity or chase above the ceiling plane (raised ceiling or fur-up chase) or below the ceilingmore » plane (dropped ceiling or fur-down) for the duct system. In this project, Building America Partnership for Improved Residential Construction team partnered with Tommy Williams Homes to implement an inexpensive, quick, and effective method of building a fur-down chase.« less

Radio Jet Feedback and Star Formation in Heavily Obscured, Hyperluminous Quasars at Redshifts ˜ 0.5-3. I. ALMA Observations

NASA Astrophysics Data System (ADS)

Lonsdale, Carol J.; Lacy, M.; Kimball, A. E.; Blain, A.; Whittle, M.; Wilkes, B.; Stern, D.; Condon, J.; Kim, M.; Assef, R. J.; Tsai, C.-W.; Efstathiou, A.; Jones, S.; Eisenhardt, P.; Bridge, C.; Wu, J.; Lonsdale, Colin J.; Jones, K.; Jarrett, T.; Smith, R.

2015-11-01

We present Atacama Large Millimeter/submillimeter Array (ALMA) 870 μm (345 GHz) data for 49 high-redshift (0.47 < z < 2.85), luminous (11.7\\lt {log}({L}{{bol}}/{L}⊙ )\\lt 14.2) radio-powerful active galactic nuclei (AGNs), obtained to constrain cool dust emission from starbursts concurrent with highly obscured radiative-mode black hole (BH) accretion in massive galaxies that possess a small radio jet. The sample was selected from the Wide-field Infrared Survey Explorer with extremely steep (red) mid-infrared colors and with compact radio emission from NVSS/FIRST. Twenty-six sources are detected at 870 μm, and we find that the sample has large mid- to far-infrared luminosity ratios, consistent with a dominant and highly obscured quasar. The rest-frame 3 GHz radio powers are 24.7\\lt {log}({P}\\text{3.0 GHz}/{{{W}} {Hz}}-1)\\lt 27.3, and all sources are radio-intermediate or radio-loud. BH mass estimates are 7.7 < log(MBH/M⊙) < 10.2. The rest-frame 1-5 μm spectral energy distributions are very similar to the “Hot DOGs” (hot dust-obscured galaxies), and steeper (redder) than almost any other known extragalactic sources. ISM masses estimated for the ALMA-detected sources are 9.9 < log (MISM/M⊙) < 11.75 assuming a dust temperature of 30 K. The cool dust emission is consistent with star formation rates reaching several thousand M⊙ yr-1, depending on the assumed dust temperature, but we cannot rule out the alternative that the AGN powers all the emission in some cases. Our best constrained source has radiative transfer solutions with approximately equal contributions from an obscured AGN and a young (10-15 Myr) compact starburst.

IC 3639 - A New Bona Fide Compton-Thick AGN Unveiled By NuSTAR

NASA Technical Reports Server (NTRS)

Boorman, Peter G.; Gandhi, P.; Alexander, D. M.; Annuar, A.; Ballantyne, D. R.; Bauer, F.; Boggs, S. E.; Brandt, W. N.; Brightman, M.; Christensen, F. E.;

X-ray constraints on the fraction of obscured active galactic nuclei at high accretion luminosities

NASA Astrophysics Data System (ADS)

Georgakakis, A.; Salvato, M.; Liu, Z.; Buchner, J.; Brandt, W. N.; Ananna, T. Tasnim; Schulze, A.; Shen, Yue; LaMassa, S.; Nandra, K.; Merloni, A.; McGreer, I. D.

2017-08-01

The wide-area XMM-XXL X-ray survey is used to explore the fraction of obscured active galactic nuclei (AGNs) at high accretion luminosities, LX(2-10 keV) ≳ 1044 erg s - 1, and out to redshift z ≈ 1.5. The sample covers an area of about 14 deg2 and provides constraints on the space density of powerful AGNs over a wide range of neutral hydrogen column densities extending beyond the Compton-thick limit, NH ≈ 1024 cm - 2. The fraction of obscured Compton-thin (NH = 1022-1024 cm - 2) AGNs is estimated to be ≈0.35 for luminosities LX(2-10 keV) > 1044 erg s - 1, independent of redshift. For less luminous sources, the fraction of obscured Compton-thin AGNs increases from 0.45 ± 0.10 at z = 0.25 to 0.75 ± 0.05 at z = 1.25. Studies that select AGNs in the infrared via template fits to the observed spectral energy distribution of extragalactic sources estimate space densities at high accretion luminosities consistent with the XMM-XXL constraints. There is no evidence for a large population of AGNs (e.g. heavily obscured) identified in the infrared and missed at X-ray wavelengths. We further explore the mid-infrared colours of XMM-XXL AGNs as a function of accretion luminosity, column density and redshift. The fraction of XMM-XXL sources that lie within the mid-infrared colour wedges defined in the literature to select AGNs is primarily a function of redshift. This fraction increases from about 20-30 per cent at z = 0.25 to about 50-70 per cent at z = 1.5.

An analysis of equine round pen training videos posted online: Differences between amateur and professional trainers

PubMed Central

Kydd, Erin; Padalino, Barbara; Henshall, Cathrynne; McGreevy, Paul

2017-01-01

Natural Horsemanship is popular among many amateur and professional trainers and as such, has been the subject of recent scientific enquiry. One method commonly adopted by Natural Horsemanship (NH) trainers is that of round pen training (RPT). RPT sessions are usually split into a series of bouts; each including two phases: chasing/flight and chasing offset/flight offset. However, NH training styles are heterogeneous. This study investigated online videos of RPT to explore the characteristics of RPT sessions and test for differences in techniques and outcomes between amateurs and professionals (the latter being defined as those with accompanying online materials that promote clinics, merchandise or a service to the public). From more than 300 candidate videos, we selected sample files for individual amateur (n = 24) and professional (n = 21) trainers. Inclusion criteria were: training at liberty in a Round Pen; more than one bout and good quality video. Sessions or portions of sessions were excluded if the trainer attached equipment, such as a lunge line, directly to the horse or the horse was saddled, mounted or ridden. The number of bouts and duration of each chasing and non-chasing phase were recorded, and the duration of each RPT session was calculated. General weighted regression analysis revealed that, when compared with amateurs, professionals showed fewer arm movements per bout (p<0.05). Poisson regression analysis showed that professionals spent more time looking up at their horses, when transitioning between gaits, than amateurs did (p<0.05). The probability of horses following the trainer was not significantly associated with amount of chasing, regardless of category. Given that, according to some practitioners, the following response is a goal of RPT, this result may prompt caution in those inclined to give chase. The horses handled by professionals showed fewer conflict behaviours (e.g. kicking, biting, stomping, head-tossing, defecating, bucking and attempting to escape), and fewer oral and head movements (e.g. head-lowering, licking and chewing) than those horses handled by amateurs Overall, these findings highlight the need for selectivity when using the internet as an educational source and the importance of trainer skill and excellent timing when using negative reinforcement in horse training. PMID:28922395

An analysis of equine round pen training videos posted online: Differences between amateur and professional trainers.

PubMed

Kydd, Erin; Padalino, Barbara; Henshall, Cathrynne; McGreevy, Paul

2017-01-01

Natural Horsemanship is popular among many amateur and professional trainers and as such, has been the subject of recent scientific enquiry. One method commonly adopted by Natural Horsemanship (NH) trainers is that of round pen training (RPT). RPT sessions are usually split into a series of bouts; each including two phases: chasing/flight and chasing offset/flight offset. However, NH training styles are heterogeneous. This study investigated online videos of RPT to explore the characteristics of RPT sessions and test for differences in techniques and outcomes between amateurs and professionals (the latter being defined as those with accompanying online materials that promote clinics, merchandise or a service to the public). From more than 300 candidate videos, we selected sample files for individual amateur (n = 24) and professional (n = 21) trainers. Inclusion criteria were: training at liberty in a Round Pen; more than one bout and good quality video. Sessions or portions of sessions were excluded if the trainer attached equipment, such as a lunge line, directly to the horse or the horse was saddled, mounted or ridden. The number of bouts and duration of each chasing and non-chasing phase were recorded, and the duration of each RPT session was calculated. General weighted regression analysis revealed that, when compared with amateurs, professionals showed fewer arm movements per bout (p<0.05). Poisson regression analysis showed that professionals spent more time looking up at their horses, when transitioning between gaits, than amateurs did (p<0.05). The probability of horses following the trainer was not significantly associated with amount of chasing, regardless of category. Given that, according to some practitioners, the following response is a goal of RPT, this result may prompt caution in those inclined to give chase. The horses handled by professionals showed fewer conflict behaviours (e.g. kicking, biting, stomping, head-tossing, defecating, bucking and attempting to escape), and fewer oral and head movements (e.g. head-lowering, licking and chewing) than those horses handled by amateurs Overall, these findings highlight the need for selectivity when using the internet as an educational source and the importance of trainer skill and excellent timing when using negative reinforcement in horse training.

Removal of central obscuration and spiders for coronagraphy

NASA Astrophysics Data System (ADS)

Abe, L.; Nishikawa, J.; Murakami, N.; Tamura, M.

2006-06-01

We present a method to remove the central obscuration and spiders, or any kind of geometry inside a telescope pupil. The technique relies on the combination of a first focal plane diffracting mask, and a complex amplitude pupil mask. In this combination, the central obscuration and eventual spider arms patterns in the re-imaged pupil (after the diffracting mask) are filled with coherent light. Adding an appropriate complex amplitude pupil mask allows virtually any kind of pupil shaping (in both amplitude and/or phase). We show that the obtained output pupil can feed a high efficiency coronagraph (any kind) with a very reasonable overall throughput and good performance even when considering pointing errors. In this paper, we specifically assess the performance of this technique when using apodized entrance pupils. This technique is relevant for ground based telescopes foreseeing the advent of higher order (so called ExAO) adaptive optics systems providing very high Strehl ratios. Some feasibility points are also discussed. adaptive optics systems providing very high Strehl ratios. Some feasibility points are also discussed.

Above-real-time training (ARTT) improves transfer to a simulated flight control task.

PubMed

Donderi, D C; Niall, Keith K; Fish, Karyn; Goldstein, Benjamin

2012-06-01

The aim of this study was to measure the effects of above-real-time-training (ARTT) speed and screen resolution on a simulated flight control task. ARTT has been shown to improve transfer to the criterion task in some military simulation experiments. We tested training speed and screen resolution in a project, sponsored by Defence Research and Development Canada, to develop components for prototype air mission simulators. For this study, 54 participants used a single-screen PC-based flight simulation program to learn to chase and catch an F-18A fighter jet with another F-18A while controlling the chase aircraft with a throttle and side-stick controller. Screen resolution was varied between participants, and training speed was varied factorially across two sessions within participants. Pretest and posttest trials were at high resolution and criterion (900 knots) speed. Posttest performance was best with high screen resolution training and when one ARTT training session was followed by a session of criterion speed training. ARTT followed by criterion training improves performance on a visual-motor coordination task. We think that ARTT influences known facilitators of transfer, including similarity to the criterion task and contextual interference. Use high-screen resolution, start with ARTT, and finish with criterion speed training when preparing a mission simulation.

Strategic Studies Quarterly. Volume 6, Number 2. Summer 2012

DTIC Science & Technology

2012-06-01

Jr . Forging an Indian Partnership Capt Craig H. Neuman II, USAF Chasing Its Tail: Nuclear Deterrence in the Information Age? Stephen J. Cimbala Commentary Our Brick Moon William H. Gerstenmaier ...Su m m er 2012 SUMMER 2012 Vol. 6, No. 2 Commentary Our Brick Moon William H. Gerstenmaier Chasing Its Tail: Nuclear Deterrence in...Extended Deterrence: How Much Strategic Force Is Too Little? David J. Trachtenberg The Common Sense of Small Nuclear Arsenals James Wood Forsyth

Modeling Syntax for Parsing and Translation

DTIC Science & Technology

2003-12-15

20 CHAPTER 2. MONOLINGUAL PROBABILISTIC PARSING a the D cat snake D S O chased S O ran SS Mary O Figure 2.1: Part of a dictionary . the cat S chased S O...along with their training algorithms: a monolingual gen- erative model of sentence structure, and a model of the relationship between the structure of a...tasks of monolingual parsing and word-level bilingual corpus alignment, they are demonstrated in two additional applications. First, a new statistical

New periodic solutions for some planar N + 3-body problems with Newtonian potentials

NASA Astrophysics Data System (ADS)

Yuan, Pengfei; Zhang, Shiqing

2018-03-01

For some planar Newtonian N + 3-body problems, we use variational minimization methods to prove the existence of new periodic solutions satisfying that N bodies chase each other on a curve, and the other 3 bodies chase each other on another curve. From the definition of orbit spaces in our paper, we can find that they are new solutions which are also different from all the examples of Ferrario and Terracini (2004).

Effects of repeated simulated removal activities on feral swine movements and space use

USGS Publications Warehouse

Fischer, Justin W.; McMurtry , Dan; Blass, Chad R.; Walter, W. David; Beringer, Jeff; VerCauterren, Kurt C.

2016-01-01

Abundance and distribution of feral swine (Sus scrofa) in the USA have increased dramatically during the last 30 years. Effective measures are needed to control and eradicate feral swine populations without displacing animals over wider areas. Our objective was to investigate effects of repeated simulated removal activities on feral swine movements and space use. We analyzed location data from 21 feral swine that we fitted with Global Positioning System harnesses in southern MO, USA. Various removal activities were applied over time to eight feral swine before lethal removal, including trapped-and-released, chased with dogs, chased with hunter, and chased with helicopter. We found that core space-use areas were reduced following the first removal activity, whereas overall space-use areas and diurnal movement distances increased following the second removal activity. Mean geographic centroid shifts did not differ between pre- and post-periods for either the first or second removal activities. Our information on feral swine movements and space use precipitated by human removal activities, such as hunting, trapping, and chasing with dogs, helps fill a knowledge void and will aid wildlife managers. Strategies to optimize management are needed to reduce feral swine populations while preventing enlarged home ranges and displacing individuals, which could lead to increased disease transmission risk and human-feral swine conflict in adjacent areas.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Donley, J. L.; Kartaltepe, J.; Kocevski, D.

While major mergers have long been proposed as a driver of both active galactic nucleus (AGN) activity and themore » $${M}_{\\mathrm{BH}}\\mbox{--}{\\sigma }_{\\mathrm{bulge}}$$ relation, studies of moderate to high-redshift Seyfert-luminosity AGN hosts have found little evidence for enhanced rates of interactions. However, both theory and observation suggest that while these AGNs may be fueled by stochastic accretion and secular processes, high-luminosity, high-redshift, and heavily obscured AGNs are the AGNs most likely to be merger-driven. To better sample this population of AGNs, we turn to infrared selection in the CANDELS/COSMOS field. Compared to their lower-luminosity and less obscured X-ray-only counterparts, IR-only AGNs (luminous, heavily obscured AGNs) are more likely to be classified as either irregular ($${50}_{-12}^{+12} \\% $$ versus $${9}_{-2}^{+5} \\% $$) or asymmetric ($${69}_{-13}^{+9} \\% $$ versus $${17}_{-4}^{+6} \\% $$) and are less likely to have a spheroidal component ($${31}_{-9}^{+13} \\% $$ versus $${77}_{-6}^{+4} \\% $$). Furthermore, IR-only AGNs are also significantly more likely than X-ray-only AGNs ($${75}_{-13}^{+8} \\% $$ versus $${31}_{-6}^{+6} \\% $$) to be classified either as interacting or merging in a way that significantly disturbs the host galaxy or as disturbed, though not clearly interacting or merging, which potentially represents the late stages of a major merger. Finally, this suggests that while major mergers may not contribute significantly to the fueling of Seyfert-luminosity AGNs, interactions appear to play a more dominant role in the triggering and fueling of high-luminosity heavily obscured AGNs.« less

75 FR 73960 - Safety Zone; “Contagion” Movie Filming, Calumet River, Chicago, IL

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-30

...-AA00 Safety Zone; ``Contagion'' Movie Filming, Calumet River, Chicago, IL AGENCY: Coast Guard, DHS... Calumet River due to the filming of a movie involving high speed boat chases and other dangerous stunts on... movie. DATES: This rule is effective from 7 a.m. on December 11, 2010 until 7 a.m. on December 12, 2010...

Removal of central obscuration and spider arm effects with beam-shaping coronagraphy

NASA Astrophysics Data System (ADS)

Abe, L.; Murakami, N.; Nishikawa, J.; Tamura, M.

2006-05-01

This paper describes a method for removing the effect of a centrally obscured aperture with additional spider arms in arbitrary geometrical configurations. The proposed method is based on a two-stage process where the light beam is first shaped to remove the central obscuration and spider arms, in order to feed a second, highly efficient coronagraph. The beam-shaping stage is a combination of a diffraction mask in the first focal plane and a complex amplitude filter located in the conjugate pupil. This paper specifically describes the case of using Lyot occulting masks and circular phase-shifting masks as diffracting components. The basic principle of the method is given along with an analytical description and numerical simulations. Substantial improvement in the performance of high-contrast coronagraphs can be obtained with this method, even if the beam-shaping filter is not perfectly manufactured.

The black hole binary V404 Cygni: a highly accreting obscured AGN analogue

NASA Astrophysics Data System (ADS)

Motta, S. E.; Kajava, J. J. E.; Sánchez-Fernández, C.; Giustini, M.; Kuulkers, E.

2017-06-01

Typical black hole binaries in outburst show spectral states and transitions, characterized by a clear connection between the inflow on to the black hole and outflows from its vicinity. The transient stellar mass black hole binary V404 Cyg apparently does not fit in this picture. Its outbursts are characterized by intense flares and intermittent plateau and low-luminosity states, with a dynamical intensity range of several orders of magnitude on time-scales of hours. During the 2015 June-July X-ray outburst a joint Swift and INTEGRAL observing campaign captured V404 Cyg in one of these plateau states. The simultaneous Swift/XRT + INTRGRAL/JEM-X + INTEGRAL/IBIS-ISGRI spectrum is reminiscent of that of obscured/absorbed active galactic nuclei (AGN). It can be modelled as a Comptonization spectrum, heavily absorbed by a partial covering, high column density material (NH ≈ 1-3 × 1024 cm-2), and a dominant reprocessed component, including a narrow iron Kα line. Such spectral distribution can be produced by a geometrically thick accretion flow able to launch a clumpy outflow, likely responsible for both the high intrinsic absorption and the intense reprocessed emission observed. Similarly to what happens in certain obscured AGN, the low-flux states might not be (solely) related to a decrease in the intrinsic luminosity, but could instead be caused by an almost complete obscuration of the inner accretion flow.

Processing of human cytomegalovirus glycoprotein B in recombinant adenovirus-infected cells.

PubMed

Marshall, G S; Fenger, D P; Stout, G G; Knights, M E; Hunt, L A

1996-07-01

Intracellular processing of human cytomegalovirus (HCMV) glycoprotein B (gB; gpUL55) expressed by a recombinant adenovirus (Ad-gB) was studied in human A549 cells as processing events could affect immunogenicity when such viruses are used as live-recombinant vaccines. Cleavage of [35S]methionine-labelled gp13O into gp93 and gp55 reached a maximum after a 3 h chase. Cleavage was completely inhibited by brefeldin A, suggesting that processing normally occurs as a late Golgi or post-Golgi event. Uncleaved gp 130 remained completely sensitive to endo-beta-N-acetylglucosaminidase H (Endo-H) in untreated cells following long chase periods, indicating high-mannose oligosaccharides at all of the 18 N-linked glycosylation sites (Asn-X-Ser/Thr) and retention in the endoplasmic reticulum. Endo-H analysis of gp55 from swainsonine-treated and untreated cells was consistent with glycosylation at all three potential sites, with two oligosaccharides remaining sensitive to Endo-H and one being processed to Endo-H resistance. The heavily glycosylated N-terminal gp93 subunit was not detected by [35S]methionine-labelling but was easily detected along with gp55 after labelling with [3H]mannose. No cleavage of gp 130 was observed in analogous pulse-chase radiolabelling of Ad-gB-infected human fibroblasts, even though these cells are permissive for HCMV replication and can process the native gB molecule. Processing of gB in recombinant adenovirus-infected A549 cells was generally similar to that previously reported for native gB in HCMV-infected fibroblasts.

Spatial distribution and cellular composition of adult brain proliferative zones in the teleost, Gymnotus omarorum

PubMed Central

Olivera-Pasilio, Valentina; Peterson, Daniel A.; Castelló, María E.

2014-01-01

Proliferation of stem/progenitor cells during development provides for the generation of mature cell types in the CNS. While adult brain proliferation is highly restricted in the mammals, it is widespread in teleosts. The extent of adult neural proliferation in the weakly electric fish, Gymnotus omarorum has not yet been described. To address this, we used double thymidine analog pulse-chase labeling of proliferating cells to identify brain proliferation zones, characterize their cellular composition, and analyze the fate of newborn cells in adult G. omarorum. Short thymidine analog chase periods revealed the ubiquitous distribution of adult brain proliferation, similar to other teleosts, particularly Apteronotus leptorhynchus. Proliferating cells were abundant at the ventricular-subventricular lining of the ventricular-cisternal system, adjacent to the telencephalic subpallium, the diencephalic preoptic region and hypothalamus, and the mesencephalic tectum opticum and torus semicircularis. Extraventricular proliferation zones, located distant from the ventricular-cisternal system surface, were found in all divisions of the rombencephalic cerebellum. We also report a new adult proliferation zone at the caudal-lateral border of the electrosensory lateral line lobe. All proliferation zones showed a heterogeneous cellular composition. The use of short (24 h) and long (30 day) chase periods revealed abundant fast cycling cells (potentially intermediate amplifiers), sparse slow cycling (potentially stem) cells, cells that appear to have entered a quiescent state, and cells that might correspond to migrating newborn neural cells. Their abundance and migration distance differed among proliferation zones: greater numbers and longer range and/or pace of migrating cells were associated with subpallial and cerebellar proliferation zones. PMID:25249943

Visual field shape and foraging ecology in diurnal raptors.

PubMed

Potier, Simon; Duriez, Olivier; Cunningham, Gregory B; Bonhomme, Vincent; O'Rourke, Colleen; Fernández-Juricic, Esteban; Bonadonna, Francesco

2018-05-18

Birds, particularly raptors, are believed to forage primarily using visual cues. However, raptor foraging tactics are highly diverse - from chasing mobile prey to scavenging - which may reflect adaptations of their visual systems. To investigate this, we studied the visual field configuration of 15 species of diurnal Accipitriformes that differ in such tactics, first focusing on the binocular field and blind area by using a single traits approach, and then exploring the shape of the binocular field with morphometric approaches. While the maximum binocular field width did not differ in species of different foraging tactics, the overall shape of their binocular fields did. In particular, raptors chasing terrestrial prey (ground predators) had a more protruding binocular field and a wider blind area above the head than did raptors chasing aerial or aquatic prey and obligate scavengers. Ground predators that forage on mammals from above have a wide but short bill - which increases ingestion rate - and large suborbital ridge to avoid sun glare. This may explain the protruding binocular field and the wide blind area above the head. By contrast, species from the two other groups have long but narrow bills used to pluck, flake or tear food and may need large visual coverage (and reduced suborbital ridges) to increase their foraging efficiency ( e.g. using large visual coverage to follow the escaping prey in three dimensions or detect conspecifics). We propose that binocular field shape is associated with bill and suborbital ridge shape and, ultimately, foraging strategies. © 2018. Published by The Company of Biologists Ltd.

Machine Learning

DTIC Science & Technology

1990-04-01

DTIC i.LE COPY RADC-TR-90-25 Final Technical Report April 1990 MACHINE LEARNING The MITRE Corporation Melissa P. Chase Cs) CTIC ’- CT E 71 IN 2 11990...S. FUNDING NUMBERS MACHINE LEARNING C - F19628-89-C-0001 PE - 62702F PR - MOlE S. AUTHO(S) TA - 79 Melissa P. Chase WUT - 80 S. PERFORMING...341.280.5500 pm I " Aw Sig rill Ia 2110-01 SECTION 1 INTRODUCTION 1.1 BACKGROUND Research in machine learning has taken two directions in the problem of

National Program for Inspection of Non-Federal Dams. Chase Pond Dam (NH 00255), NHWRB Number 253.02, Merrimack River Basin, Wilmot, New Hampshire. Phase I Inspection Report.

DTIC Science & Technology

1980-03-01

STANDAROS-1963-A L ~.°.. o...... 1....MERRIMACK RIVER BASIN -!. WILMOT , NEW HAMPSHIRE ’,- CHASE POND DAM NH 00255 NHWRB NO. 253.02 r PHASE I...Continue on fewsorsp side #0 .o..oemay and Ientify by black Muthot) - DAMS, NSPECTION, PAM S’AFETY, Merrimack River Basin. * Wilmot , New Hampshire...MERRIMACK RIVER BASIN R WILMOT , NEW HAMPSHIRE - - PHASE I INSPECTION REPORT NATIONAL DAM INSPECTION PROGRAM :: : I

Application of curative therapy in the ward. 1920.

PubMed

Marble, Henry Chase

2009-06-01

This Classic article is a reprint of the original work by Henry Chase Marble, Application of Curative Therapy in the Ward. An accompanying biographical sketch on Henry Chase Marble, MD, is available at DOI 10.1007/s11999-009-0789-7 . The Classic Article is (c)1920 by the Journal of Bone and Joint Surgery, Inc. and is reprinted with permission from Marble HC. Application of curative therapy in the ward. J Bone Joint Surg Am. 1920;2:136-138.

The F-18 simulator at NASA's Dryden Flight Research Center, Edwards, California

NASA Image and Video Library

2004-10-04

The F-18 simulator at NASA's Dryden Flight Research Center, Edwards, California. Simulators offer a safe and economical alternative to actual flights to gather data, as well as being excellent facilities for pilot practice and training. The F-18 Hornet is used primarily as a safety chase and mission support aircraft at NASA's Dryden Flight Research Center, Edwards, California. As support aircraft, the F-18's are used for safety chase, pilot proficiency, aerial photography and other mission support functions.

Social grouping: perceptual grouping of objects by cooperative but not competitive relationships in dynamic chase.

PubMed

Yin, Jun; Ding, Xiaowei; Zhou, Jifan; Shui, Rende; Li, Xinyu; Shen, Mowei

2013-10-01

Historically, perceptual grouping is associated with physical principles. This article reports a novel finding that social information-cooperative but not competitive relationships-can drive perceptual grouping of objects in dynamic chase. Particularly, each relationship was constructed with human-generated chasing motions (i.e., two predators and one prey), and its role on perceptual grouping was examined by grouping-induced effect-attentional consequences. The results showed that: (1) Predators can be perceived as a group due to their cooperative relationship, causing attention to automatically spread within grouped predators, thus the response to target appearing on uncued predator is also facilitated; and (2) The attentional effect on competitive predators has no difference from any condition which controls low-level motion patterns, even including the random-motion condition wherein no grouping factor was contained. These findings extend perceptual grouping into the social field, implying that social information gets involved in visual cognition at an early perceptual stage. Copyright © 2013 Elsevier B.V. All rights reserved.

Building America Case Study: Duct in Conditioned Space in a Dropped Ceiling or Fur-down, Gainesville, Florida (Fact Sheet)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

2014-09-01

Forced air distribution systems (duct systems) typically are installed out of sight for aesthetic reasons, most often in unconditioned areas such as an attic or crawlspace. Any leakage of air to or from the duct system (duct leakage) in unconditioned space not only loses energy, but impacts home and equipment durability and indoor air quality. An obvious solution to this problem is to bring the duct system into the interior of the house, either by sealing the area where the ducts are installed (sealed attic or crawlspace) or by building an interior cavity or chase above the ceiling plane (raisedmore » ceiling or fur-up chase) or below the ceiling plane (dropped ceiling or fur-down) for the duct system. This case study examines one Building America builder partner's implementation of an inexpensive, quick and effective method of building a fur-down or dropped ceiling chase.« less

Pattern production through a chiral chasing mechanism

NASA Astrophysics Data System (ADS)

Woolley, Thomas E.

2017-09-01

Recent experiments on zebrafish pigmentation suggests that their typical black and white striped skin pattern is made up of a number of interacting chromatophore families. Specifically, two of these cell families have been shown to interact through a nonlocal chasing mechanism, which has previously been modeled using integro-differential equations. We extend this framework to include the experimentally observed fact that the cells often exhibit chiral movement, in that the cells chase, and run away, at angles different to the line connecting their centers. This framework is simplified through the use of multiple small limits leading to a coupled set of partial differential equations which are amenable to Fourier analysis. This analysis results in the production of dispersion relations and necessary conditions for a patterning instability to occur. Beyond the theoretical development and the production of new pattern planiforms we are able to corroborate the experimental hypothesis that the global pigmentation patterns can be dependent on the chirality of the chromatophores.

Goal attribution to inanimate moving objects by Japanese macaques (Macaca fuscata)

PubMed Central

Atsumi, Takeshi; Koda, Hiroki; Masataka, Nobuo

2017-01-01

Humans interpret others’ goals based on motion information, and this capacity contributes to our mental reasoning. The present study sought to determine whether Japanese macaques (Macaca fuscata) perceive goal-directedness in chasing events depicted by two geometric particles. In Experiment 1, two monkeys and adult humans were trained to discriminate between Chasing and Random sequences. We then introduced probe stimuli with various levels of correlation between the particle trajectories to examine whether participants performed the task using higher correlation. Participants chose stimuli with the highest correlations by chance, suggesting that correlations were not the discriminative cue. Experiment 2 examined whether participants focused on particle proximity. Participants differentiated between Chasing and Control sequences; the distance between two particles was identical in both. Results indicated that, like humans, the Japanese macaques did not use physical cues alone to perform the discrimination task and integrated the cues spontaneously. This suggests that goal attribution resulting from motion information is a widespread cognitive phenotype in primate species. PMID:28053305

Effects of chronic metal exposure and sediment organic matter on digestive absorption efficiency of cadmium by the deposit-feeding polychaete Capitella species I

DOE Office of Scientific and Technical Information (OSTI.GOV)

Selck, H.; Forbes, V.E.; Decho, A.W.

1999-06-01

Organic matter such as humic acid and bacterial slime exopolymer are common in estuarine and coastal sediments, where they are ingested by animals that process particulate detritus. Both humic acid (HA; refractory) and exopolymer (EPS; easily digestible) bind metals and therefore might represent a source of particulate-bound metals to deposit-feeding organisms. This study examined how cadmium preexposure, gut passage time (GPT), and quality and quantity of the organic coating on sediment particles interact to determine cadmium absorption efficiency (Cd-AE) in Capitella sp. I. Pulse-chase experiments using [sup 109]Cd and [sup 51]Cr were used to determine Cd-AE in individual worms. Wormsmore » were given a pulse of carbon-cleaned, HA-coated or EPS-coated sediment particles. The third treatment was divided into three EPS concentrations (high, medium, and low). A 5-d preexposure to cadmium did not affect the egestion rates during either the preexposure period or the chase phase. Worms given a pulse of carbon-cleaned particles exhibited higher egestion rates during the chase phase than worms given a pulse of organic-coated particles, and no differences were seen in egestion rate between worms exposed to HA- and high-EPS-coated particles. Egestion rates decreased with increasing EPS concentration. The presence of refractory organic material decreased the absorption efficiency of cadmium from sediment relative to Cd-AE from carbon-cleaned sediment but not relative to Cd-AE from sediment coated with a high concentration of EPS. The Cd-AE increased linearly with increasing exopolymer coating on sediment particles. Overall, Cd-AE increased with increasing gut passage time in worms that were not preexposed, although Cd-AE from HA-coated particles was independent of gut passage time. Preexposure to cadmium reversed the relationship between gut passage time and cadmium absorption efficiency. Thus, the implications are that sedimentary organic matter and worm physiology might be especially important in controlling metal bioavailability in deposit-feeding organisms and should be considered in sediment quality approaches.« less

Remembering Dr. George J. Apel, Jr: A Posthumous Tribute to an Innovative, Obscure Pioneer in Christian Higher Education

ERIC Educational Resources Information Center

Lumadue, Richard T.

2007-01-01

This paper is a belated tribute to George J. Apel, Jr., an innovative and obscure Christian higher educator. Peruse the name and subject indices of any and all books about Christian higher education, and nowhere will there appear even a reference to George J. Apel, Jr. Although Apel never finished high school or college, he was awarded an honorary…

Measuring the Clustering Around Normal and Dust-Obscured Quasars at 2 in the Spitzer Extragalactic Representative Volume Survey (SERVS)

NASA Astrophysics Data System (ADS)

Jones, Kristen M.; Lacy, M.; Spitzer Extragalactic Representative Volume Survey Team

2014-01-01

Little is known about the environments of high redshift quasars, particularly those obscured by dust. Previous work suggests that dust-shrouded (type 2) quasars are at least as common as un-obscured optical (type 1) quasars; therefore, in order to fully understand the role quasars play in the evolutionary history of the universe, we must understand both types of objects. This project seeks to explore the environments in which obscured quasars form. In this poster, we present mid-infrared clustering measurements for a sample of 45 quasars with 1.3 < z < 2.5, a redshift range that is unexplored in the literature. The objects were selected using IRAC multi-color criteria to remove low-redshift starburst and quiescent galaxies, and subsequently had spectroscopy carried out to both obtain redshifts, and to distinguish between type 1 and type 2 quasars; the high-redshift sample presented in this paper is roughly evenly distributed between the two types. We use the SERVS galaxy catalogs to estimate the cross-correlation between each quasar and its surrounding galaxies. The amplitude of this function gives us the richness of the environments in which these quasars are found, and we compare our results with a matched sample with z < 1.3.

Long-term US energy outlook

DOE Office of Scientific and Technical Information (OSTI.GOV)

Friesen, G.

Chase Econometrics summarizes the assumptions underlying long-term US energy forecasts. To illustrate the uncertainty involved in forecasting for the period to the year 2000, they compare Chase Econometrics forecasts with some recent projections prepared by the DOE Office of Policy, Planning and Analysis for the annual National Energy Policy Plan supplement. Scenario B, the mid-range reference case, is emphasized. The purpose of providing Scenario B as well as Scenarios A and C as alternate cases is to show the sensitivity of oil price projections to small swings in energy demand. 4 tables.

Combat History Analysis Study Effort (CHASE) Data Enhancement Study (CDES). Volume 1. Introductory Materials and Bioliography.

DTIC Science & Technology

1986-01-31

Operations, France and Belgium, 1914: Mons, the Retreat to the Seine , the Marne , the Aisne, August-October 1914. London, 1922. Edmonds, Brig. Gen...7-175 712 COMBAT HISTORY ANAL YSIS STUDY EFFORT (CHASE) DATA l/f ENHANCEMENT STUDY CDES (U) DATA MEMORY SYSTEMS INC FAIRFAX VA HERO DIV B R BADER ET ...Fleville 350 Noyon-Montdidier 378 Hill 212 351 Champagne- Marne 379 Bois de Boyon- 352 Aisne- Marne I Montrefagne 353 Missy aux Bois Ravine 380 Hill 272 354

The CHilean Automatic Supernova sEarch (CHASE)

NASA Astrophysics Data System (ADS)

Pignata, G.; Maza, J.; Hamuy, M.; Antezana, R.; Gonzales, L.

2009-05-01

One of the most important challenges in modern cosmology will be to figure out the origin of the dark energy, to measure its equation of state and the time rate with which it changes (described by parameters w and w'). The measurement of these parameters will require high levels of accuracy in the Supernova (SN) Type Ia distances and various sources of systematic error such as reddening corrections and possible evolution in the SNcharacteristics which could couple with redshift and mimic the cosmological signal of interest. Fortunately, these concerns can be fully addressed through the comprehensive study of SNe in the local (z < 0.05) universe. Although Type II plateau SNe are not as luminous as SNe Ia, they afford two important, independent routes to cosmological distances using the Expanding Photosphere Method and the Standardized Candle Method. To assess the performance of these techniques a nearby sample of Type II SNe is necessary. With the purpose of addressing these issues the Millennium Center for Supernova Studies (MCSS) is teaming up with the Carnegie Supernova Project (CSP) to carry out an optical and near infrared (photometry, spectroscopy and polarimetry) follow up of nearby SNe. Unfortunately, the majority of the SNe observed by the MCSS and the CSP are discovered by searches carried out from the northern hemisphere. This entails a number of observational difficulties, in particular, it reduces the number of SNe for which the follow-up starts at very early epochs. The aim of the CHASE project is to remove this search bias by discovering young Southern SNe that will be extensively observed by the MCSS and the CSP. In the first nine-months of operation, CHASE has discovered two SNe: SN007oc (CBET 1114) and SN007pl (CBET 1130), thus demonstrating the feasibility of the survey.

Intracellular accumulation and oligosaccharide processing of alkaline phosphatase under disassembly of the Golgi complex caused by brefeldin A.

PubMed

Takami, N; Oda, K; Fujiwara, T; Ikehara, Y

1990-12-27

Electron microscopic observations showed that the fungal metabolite brefeldin A caused disassembly of the Golgi complex in human choriocarcinoma cells and accumulation of alkaline phosphatase (ALP) in the endoplasmic reticulum (ER) and nuclear envelope, where ALP was not apparently detectable in control cells. Pulse/chase experiments with [35S]methionine demonstrated that in the control cells, ALP synthesized as a 63-kDa precursor form was rapidly converted to a 66-kDa form, by processing of its N-linked oligosaccharides from the high-mannose type to the complex type, which was expressed on the cell surface after 30 min of chase. In contrast, in the brefeldin-A-treated cells the precursor was gradually converted to a 65-kDa form, slightly smaller than the control mature form, which was not expressed on the cell surface even after a prolonged time of chase. Kinetics of the ALP processing in the brefeldin-A-treated cells demonstrated that the precursor was initially converted to an intermediate form, partially sensitive to endo-beta-N-acetylglucosaminidase H (endo H), then to an endo-H-resistant 65-kDa form. In addition, this form was found to be sensitive to neuraminidase digestion, though its sialylation was not so complete as that of the control mature form. Taken together, these results suggest that under disassembly of the Golgi complex caused by brefeldin A, oligosaccharide-processing enzymes including sialyltransferase, an enzyme in the trans Golgi cisterna(e) and/or the trans Golgi network, might be redistributed into the ER and involved in processing of the oligosaccharides of ALP accumulating there.

Simulated predator stimuli reduce brain cell proliferation in two electric fish species, Brachyhypopomus gauderio and Apteronotus leptorhynchus.

PubMed

Dunlap, Kent D; Keane, Geoffrey; Ragazzi, Michael; Lasky, Elise; Salazar, Vielka L

2017-07-01

The brain structure of many animals is influenced by their predators, but the cellular processes underlying this brain plasticity are not well understood. Previous studies showed that electric fish ( Brachyhypopomus occidentalis ) naturally exposed to high predator ( Rhamdia quelen ) density and tail injury had reduced brain cell proliferation compared with individuals facing few predators and those with intact tails. However, these field studies described only correlations between predator exposure and cell proliferation. Here, we used a congener Brachyhypopomus gauderio and another electric fish Apteronotus leptorhynchus to experimentally test the hypothesis that exposure to a predator stimulus and tail injury causes alterations in brain cell proliferation. To simulate predator exposure, we either amputated the tail followed by short-term (1 day) or long-term (17-18 days) recovery or repeatedly chased intact fish with a plastic rod over a 7 day period. We measured cell proliferation (PCNA+ cell density) in the telencephalon and diencephalon, and plasma cortisol, which commonly mediates stress-induced changes in brain cell proliferation. In both species, either tail amputation or simulated predator chase decreased cell proliferation in the telencephalon in a manner resembling the effect of predators in the field. In A. leptorhynchus , cell proliferation decreased drastically in the short term after tail amputation and partially rebounded after long-term recovery. In B. gauderio , tail amputation elevated cortisol levels, but repeated chasing had no effect. In A. leptorhynchus , tail amputation elevated cortisol levels in the short term but not in the long term. Thus, predator stimuli can cause reductions in brain cell proliferation, but the role of cortisol is not clear. © 2017. Published by The Company of Biologists Ltd.

Heavy X-ray obscuration in the most luminous galaxies discovered by WISE

NASA Astrophysics Data System (ADS)

Vito, F.; Brandt, W. N.; Stern, D.; Assef, R. J.; Chen, C.-T. J.; Brightman, M.; Comastri, A.; Eisenhardt, P.; Garmire, G. P.; Hickox, R.; Lansbury, G.; Tsai, C.-W.; Walton, D. J.; Wu, J. W.

2018-03-01

Hot dust-obscured galaxies (DOGs) are hyperluminous (L8-1000 μm > 1013 L⊙) infrared galaxies with extremely high (up to hundreds of K) dust temperatures. The sources powering both their extremely high luminosities and dust temperatures are thought to be deeply buried and rapidly accreting supermassive black holes (SMBHs). Hot DOGs could therefore represent a key evolutionary phase in which the SMBH growth peaks. X-ray observations can be used to study their obscuration levels and luminosities. In this work, we present the X-ray properties of the 20 most luminous (Lbol ≳ 1014 L⊙) known hot DOGs at z = 2-4.6. Five of them are covered by long-exposure (10-70 ks) Chandra and XMM-Newton observations, with three being X-ray detected, and we study their individual properties. One of these sources (W0116-0505) is a Compton-thick candidate, with column density NH = (1.0-1.5) × 1024 cm-2 derived from X-ray spectral fitting. The remaining 15 hot DOGs have been targeted by a Chandra snapshot (3.1 ks) survey. None of these 15 are individually detected; therefore, we applied a stacking analysis to investigate their average emission. From hardness ratio analysis, we constrained the average obscuring column density and intrinsic luminosity to be log NH (cm-2) > 23.5 and LX ≳ 1044 erg s-1, which are consistent with results for individually detected sources. We also investigated the LX-L6 μm and LX-Lbol relations, finding hints that hot DOGs are typically X-ray weaker than expected, although larger samples of luminous obscured quasi-stellar objects are needed to derive solid conclusions.

Biosynthesis, targeting, and processing of lysosomal proteins: pulse-chase labeling and immune precipitation.

PubMed

Pohl, Sandra; Hasilik, Andrej

2015-01-01

Incorporation of radioactive precursors of amino acids and/or modifier groups into proteins, isolation and sizing of polypeptide species of interest, and finally their detection and characterization provide a robust handle to examine the life cycle and varied modifications of any protein. A prerequisite in application of these techniques to lysosomal enzymes is the availability of an avid and specific antibody, because lysosomal proteins represent a very minor fraction of the cellular protein and must be purified without a significant loss many 1000-fold as conveniently as possible. Pulse-chase labeling and good knowledge on organelle-specific modifications of lysosomal proteins may enhance the information that can be obtained from such experiments. We describe procedures for pulse-chase labeling experiments that have proven to work with a commercially available antibody against a mouse and a human lysosomal protease and can be used as a reference in establishing the technique in any laboratory that has an access to a certified isotope facility and the knowledge to handle radioactivity safely. We discuss the crucial steps and refer to alternatives described in the literature. The present model protein cathepsin Z is synthesized as a larger proenzyme that contains two N-linked oligosaccharides and matures to a shorter single chain enzyme retaining the processed oligosaccharides. A pulse-chase experiment demonstrates the conversion of the precursor into the mature form. In addition, results on deglycosylation of metabolically labeled cathepsin Z are shown and the alterations in the apparent size of the glycopeptides are explained. Copyright © 2015 Elsevier Inc. All rights reserved.

Duration of effects of acute environmental changes on food anticipatory behaviour, feed intake, oxygen consumption, and cortisol release in Atlantic salmon parr.

PubMed

Folkedal, Ole; Torgersen, Thomas; Olsen, Rolf Erik; Fernö, Anders; Nilsson, Jonatan; Oppedal, Frode; Stien, Lars H; Kristiansen, Tore S

2012-01-18

We compared behavioural and physiological responses and recovery time after different acute environmental challenges in groups of salmon parr. The fish were prior to the study conditioned to a flashing light signalling arrival of food 30 s later to study if the strength of Pavlovian conditioned food anticipatory behaviour can be used to assess how salmon parr cope with various challenges. The effect on anticipatory behaviour was compared to the effect on feed intake and physiological responses of oxygen hyper-consumption and cortisol excretion. The challenges were temperature fluctuation (6.5C° over 4 h), hyperoxia (up to 380% O(2) saturation over 4 h), and intense chasing for 10 min. Cortisol excretion was only elevated after hyperoxia and chasing, and returned to baseline levels after around 3 h or less. Oxygen hyper-consumption persisted for even shorter periods. Feed intake was reduced the first feeding after all challenges and recovered within 3 h after temperature and hyperoxia, but was reduced for days after chasing. Food anticipatory behaviour was reduced for a longer period than feed intake after hyperoxia and was low at least 6 h after chasing. Our findings suggest that a recovery of challenged Atlantic salmon parr to baseline levels of cortisol excretion and oxygen consumption does not mean full recovery of all psychological and physiological effects of environmental challenges, and emphasise the need for measuring several factors including behavioural parameters when assessing fish welfare. Copyright © 2011 Elsevier Inc. All rights reserved.

Measure Guideline: Summary of Interior Ducts in New Construction, Including an Efficient, Affordable Method to Install Fur-Down Interior Ducts

DOE Office of Scientific and Technical Information (OSTI.GOV)

Beal, D.; McIlvaine , J.; Fonorow, K.

2011-11-01

This document illustrates guidelines for the efficient installation of interior duct systems in new housing, including the fur-up chase method, the fur-down chase method, and interior ducts positioned in sealed attics or sealed crawl spaces. This document illustrates guidelines for the efficient installation of interior duct systems in new housing. Interior ducts result from bringing the duct work inside a home's thermal and air barrier. Architects, designers, builders, and new home buyers should thoroughly investigate any opportunity for energy savings that is as easy to implement during construction, such as the opportunity to construct interior duct work. In addition tomore » enhanced energy efficiency, interior ductwork results in other important advantages, such as improved indoor air quality, increased system durability and increased homeowner comfort. While the advantages of well-designed and constructed interior duct systems are recognized, the implementation of this approach has not gained a significant market acceptance. This guideline describes a variety of methods to create interior ducts including the fur-up chase method, the fur-down chase method, and interior ducts positioned in sealed attics or sealed crawl spaces. As communication of the intent of an interior duct system, and collaboration on its construction are paramount to success, this guideline details the critical design, planning, construction, inspection, and verification steps that must be taken. Involved in this process are individuals from the design team; sales/marketing team; and mechanical, insulation, plumbing, electrical, framing, drywall and solar contractors.« less

Dust-obscured star-forming galaxies in the early universe

NASA Astrophysics Data System (ADS)

Wilkins, Stephen M.; Feng, Yu; Di Matteo, Tiziana; Croft, Rupert; Lovell, Christopher C.; Thomas, Peter

2018-02-01

Motivated by recent observational constraints on dust reprocessed emission in star-forming galaxies at z ∼ 6 and above, we use the very large cosmological hydrodynamical simulation BLUETIDES to explore predictions for the amount of dust-obscured star formation in the early Universe (z > 8). BLUETIDES matches current observational constraints on both the UV luminosity function and galaxy stellar mass function and predicts that approximately 90 per cent of the star formation in high-mass (M* > 1010 M⊙) galaxies at z = 8 is already obscured by dust. The relationship between dust attenuation and stellar mass predicted by BLUETIDES is consistent with that observed at lower redshift. However, observations of several individual objects at z > 6 are discrepant with the predictions, though it is possible that their uncertainties may have been underestimated. We find that the predicted surface density of z ≥ 8 submm sources is below that accessible to current Herschel, SCUBA-2 and Atacama Large Millimetre Array (ALMA) submm surveys. However, as ALMA continues to accrue an additional surface area the population of z > 8 dust-obscured galaxies may become accessible in the near future.

An Imperfectly Passive Nature: Bright Submillimeter Emission from Dust-obscured Star Formation in the z = 3.717 “Passive” System, ZF 20115

NASA Astrophysics Data System (ADS)

Simpson, J. M.; Smail, Ian; Wang, Wei-Hao; Riechers, D.; Dunlop, J. S.; Ao, Y.; Bourne, N.; Bunker, A.; Chapman, S. C.; Chen, Chian-Chou; Dannerbauer, H.; Geach, J. E.; Goto, T.; Harrison, C. M.; Hwang, H. S.; Ivison, R. J.; Kodama, Tadayuki; Lee, C.-H.; Lee, H.-M.; Lee, M.; Lim, C.-F.; Michałowski, M. J.; Rosario, D. J.; Shim, H.; Shu, X. W.; Swinbank, A. M.; Tee, W.-L.; Toba, Y.; Valiante, E.; Wang, Junxian; Zheng, X. Z.

2017-07-01

The identification of high-redshift, massive galaxies with old stellar populations may pose challenges to some models of galaxy formation. However, to securely classify a galaxy as quiescent, it is necessary to exclude significant ongoing star formation, something that can be challenging to achieve at high redshifts. In this Letter, we analyze deep ALMA/870 μm and SCUBA-2/450 μm imaging of the claimed “post-starburst” galaxy ZF 20115 at z = 3.717 that exhibits a strong Balmer break and absorption lines. The rest-frame far-infrared imaging identifies a luminous starburst 0.″4 ± 0.″1 (˜3 kpc in projection) from the position of the ultraviolet/optical emission and is consistent with lying at the redshift of ZF 20115. The star-forming component, with an obscured star formation rate of {100}-70+15 {M}⊙ {{yr}}-1, is undetected in the rest-frame ultraviolet but contributes significantly to the lower angular resolution photometry at rest-frame wavelengths ≳3500 Å. This contribution from the obscured starburst, especially in the Spitzer/IRAC wavebands, significantly complicates the determination of a reliable stellar mass for the ZF 20015 system, and we conclude that this source does not pose a challenge to current models of galaxy formation. The multi-wavelength observations of ZF 20115 unveil a complex system with an intricate and spatially varying star formation history. ZF 20115 demonstrates that understanding high-redshift obscured starbursts will only be possible with multi-wavelength studies that include high-resolution observations, available with the James Webb Space Telescope, at mid-infrared wavelengths.

Anatomy of the AGN in NGC 5548. VII. Swift study of obscuration and broadband continuum variability

NASA Astrophysics Data System (ADS)

Mehdipour, M.; Kaastra, J. S.; Kriss, G. A.; Cappi, M.; Petrucci, P.-O.; De Marco, B.; Ponti, G.; Steenbrugge, K. C.; Behar, E.; Bianchi, S.; Branduardi-Raymont, G.; Costantini, E.; Ebrero, J.; Di Gesu, L.; Matt, G.; Paltani, S.; Peterson, B. M.; Ursini, F.; Whewell, M.

2016-04-01

We present our investigation into the long-term variability of the X-ray obscuration and optical-UV-X-ray continuum in the Seyfert 1 galaxy NGC 5548. In 2013 and 2014, the Swift observatory monitored NGC 5548 on average every day or two, with archival observations reaching back to 2005, totalling about 670 ks of observing time. Both broadband spectral modelling and temporal rms variability analysis are applied to the Swift data. We disentangle the variability caused by absorption, due to an obscuring weakly-ionised outflow near the disk, from variability of the intrinsic continuum components (the soft X-ray excess and the power law) originating in the disk and its associated coronae. The spectral model that we apply to this extensive Swift data is the global model that we derived for NGC 5548 from analysis of the stacked spectra from our multi-satellite campaign of 2013 (including XMM-Newton, NuSTAR, and HST). The results of our Swift study show that changes in the covering fraction of the obscurer is the primary and dominant cause of variability in the soft X-ray band on timescales of 10 days to ~5 months. The obscuring covering fraction of the X-ray source is found to range between 0.7 and nearly 1.0. The contribution of the soft excess component to the X-ray variability is often much less than that of the obscurer, but it becomes comparable when the optical-UV continuum flares up. We find that the soft excess is consistent with being the high-energy tail of the optical-UV continuum and can be explained by warm Comptonisation: up-scattering of the disk seed photons in a warm, optically thick corona as part of the inner disk. To this date, the Swift monitoring of NGC 5548 shows that the obscurer has been continuously present in our line of sight for at least 4 years (since at least February 2012).

Artificial selection for food colour preferences.

PubMed

Cole, Gemma L; Endler, John A

2015-04-07

Colour is an important factor in food detection and acquisition by animals using visually based foraging. Colour can be used to identify the suitability of a food source or improve the efficiency of food detection, and can even be linked to mate choice. Food colour preferences are known to exist, but whether these preferences are heritable and how these preferences evolve is unknown. Using the freshwater fish Poecilia reticulata, we artificially selected for chase behaviour towards two different-coloured moving stimuli: red and blue spots. A response to selection was only seen for chase behaviours towards the red, with realized heritabilities ranging from 0.25 to 0.30. Despite intense selection, no significant chase response was recorded for the blue-selected lines. This lack of response may be due to the motion-detection mechanism in the guppy visual system and may have novel implications for the evolvability of responses to colour-related signals. The behavioural response to several colours after five generations of selection suggests that the colour opponency system of the fish may regulate the response to selection. © 2015 The Author(s) Published by the Royal Society. All rights reserved.

Magnetic state selected by magnetic dipole interaction in the kagome antiferromagnet NaBa2Mn3F11

NASA Astrophysics Data System (ADS)

Hayashida, Shohei; Ishikawa, Hajime; Okamoto, Yoshihiko; Okubo, Tsuyoshi; Hiroi, Zenji; Avdeev, Maxim; Manuel, Pascal; Hagihala, Masato; Soda, Minoru; Masuda, Takatsugu

2018-02-01

We haved studied the ground state of the classical kagome antiferromagnet NaBa2Mn3F11 . Strong magnetic Bragg peaks observed for d spacings shorter than 6.0 Å were indexed by the propagation vector of k0=(0 ,0 ,0 ) . Additional peaks with weak intensities in the d -spacing range above 8.0 Å were indexed by the incommensurate vector of k1=[0.3209 (2 ) ,0.3209 (2 ) ,0 ] and k2=[0.3338 (4 ) ,0.3338 (4 ) ,0 ] . Magnetic structure analysis unveils a 120∘ structure with the tail-chase geometry having k0 modulated by the incommensurate vector. A classical calculation of the Heisenberg kagome antiferromagnet with antiferromagnetic second-neighbor interaction, for which the ground state a k0120∘ degenerated structure, reveals that the magnetic dipole-dipole (MDD) interaction including up to the fourth neighbor terms selects the tail-chase structure. The observed modulation of the tail-chase structure is attributed to a small perturbation such as the long-range MDD interaction or the interlayer interaction.

Artificial selection for food colour preferences

PubMed Central

Cole, Gemma L.; Endler, John A.

2015-01-01

Colour is an important factor in food detection and acquisition by animals using visually based foraging. Colour can be used to identify the suitability of a food source or improve the efficiency of food detection, and can even be linked to mate choice. Food colour preferences are known to exist, but whether these preferences are heritable and how these preferences evolve is unknown. Using the freshwater fish Poecilia reticulata, we artificially selected for chase behaviour towards two different-coloured moving stimuli: red and blue spots. A response to selection was only seen for chase behaviours towards the red, with realized heritabilities ranging from 0.25 to 0.30. Despite intense selection, no significant chase response was recorded for the blue-selected lines. This lack of response may be due to the motion-detection mechanism in the guppy visual system and may have novel implications for the evolvability of responses to colour-related signals. The behavioural response to several colours after five generations of selection suggests that the colour opponency system of the fish may regulate the response to selection. PMID:25740894

Ex vivo preservation and expansion of human limbal epithelial stem cells on amniotic membrane cultures.

PubMed

Meller, D; Pires, R T F; Tseng, S C G

2002-04-01

Amniotic membrane (AM) transplantation effectively expands the remaining limbal epithelial stem cells in patients with partial limbal stem cell deficiency. The authors investigated whether this action could be produced ex vivo. The outgrowth rate on AM was compared among explants derived from human limbus, peripheral cornea, and central cornea. For outgrowth of human limbal epithelial cells (HLEC), cell cycle kinetics were measured by BrdU labelling for 1 or 7 days, of which the latter was also chased in primary cultures, secondary 3T3 fibroblast cultures, and in athymic Balb/c mice following a brief treatment with a phorbol ester. Epithelial morphology was studied by histology and transmission electron microscopy, and phenotype was defined by immunostaining with monoclonal antibodies to keratins and mucins. Outgrowth rate was 0/22 (0%) and 2/24 (8.3%) for central and peripheral corneal explants, respectively, but was 77/80 (96.2%) for limbal explants (p <0.0001). 24 hour BrdU labelling showed a uniformly low (that is, less than 5%) labelling index in 65% of the limbal explants, but a mixed pattern with areas showing a high (that is, more than 40%) labelling index in 35% of limbal explants, and in all (100%) peripheral corneal explants. Continuous BrdU labelling for 7 days detected a high labelling index in 61.5% of the limbal explants with the remainder still retaining a low labelling index. A number of label retaining cells were noted after 7 day labelling followed by 14 days of chase in primary culture or by 21 days of chase after transplantation to 3T3 fibroblast feeder layers. After exposure to phorbol 12-myristate 13-acetate for 24 hours and 7 day labelling, HLEC transplanted in athymic mice still showed a number of label retaining basal cells after 9 days of chase. HLEC cultured on AM were strongly positive for K14 keratin and MUC4 and slightly positive in suprabasal cells for K3 keratin but negative for K12 keratin, AMEM2, and MUC5AC. After subcutaneous implantation in athymic mice, the resultant epithelium was markedly stratified and the basal epithelial cells were strongly positive for K14 keratin, while the suprabasal epithelial cells were strongly positive for K3 keratin and MUC4, and the entire epithelium was negative for K12 keratin and MUC5A/C. These data support the notion that AM cultures preferentially preserve and expand limbal epithelial stem cells that retain their in vivo properties of slow cycling, label retaining, and undifferentiation. This finding supports the feasibility of ex vivo expansion of limbal epithelial stem cells for treating patients with total limbal stem cell deficiency using a small amount of donor limbal tissue.

Luminous Obscured AGN Unveiled in the Stripe 82 X-ray Survey

NASA Astrophysics Data System (ADS)

LaMassa, Stephanie; Glikman, Eilat; Brusa, Marcella; Rigby, Jane; Tasnim Ananna, Tonima; Stern, Daniel; Lira, Paulina; Urry, Meg; Salvato, Mara; Alexandroff, Rachael; Allevato, Viola; Cardamone, Carolin; Civano, Francesca Maria; Coppi, Paolo; Farrah, Duncan; Komossa, S.; Lanzuisi, Giorgio; Marchesi, Stefano; Richards, Gordon; Trakhtenbrot, Benny; Treister, Ezequiel

2018-01-01

Stripe 82X is a wide-area (30 deg2) X-ray survey overlapping the legacy Sloan Digital Sky Survey (SDSS) Stripe 82 field, designed to uncover rare, high luminosity active galactic nuclei (AGN). We report on the results of an on-going near-infrared (NIR) spectroscopic campaign to follow-up reddened AGN candidates with Palomar TripleSpec, Keck NIRSPEC, and Gemini GNIRS. We identified 8 AGN in our bright NIR sample (K < 16, Vega), selected to have red R-K colors (> 4, Vega); four of these sources had existing optical spectra in SDSS. We targeted four out of 34 obscured AGN candidates in our faint NIR sample (K > 17, Vega), all of which are undetected in the single-epoch SDSS imaging, making them the best candidates for the most obscured and/or the most distant reddend AGN in Stripe 82X. All twelve sources are Type 1 AGN, with the FWHM of at least one permitted emission line exceeding 1300 km/s. We find that our nearly complete bright NIR sample (12/13 obscured AGN candidates have spectroscopic redshifts) is more distant (z > 0.5) than a matched sample of blue Type 1 AGN from Stripe 82X; these AGN tend to be more luminous than their blue, unobscured counterparts. Results from our pilot program of faint NIR-selected obscured AGN candidates demonstrate that our selection recovers reddened quasars missed by SDSS.

Virtual chromoendoscopy improves the diagnostic yield of small bowel capsule endoscopy in obscure gastrointestinal bleeding.

PubMed

Boal Carvalho, Pedro; Magalhães, Joana; Dias de Castro, Francisca; Gonçalves, Tiago Cúrdia; Rosa, Bruno; Moreira, Maria João; Cotter, José

2016-02-01

Small bowel capsule endoscopy represents the initial investigation for obscure gastrointestinal bleeding. Flexible spectral imaging colour enhancement (FICE) is a virtual chromoendoscopy technique designed to enhance mucosal lesions, available in different settings according to light wavelength-- FICE1, 2 and 3. To compare the diagnostic yield of FICE1 and white light during capsule endoscopy in patients with obscure gastrointestinal bleeding. Retrospective single-centre study including 60 consecutive patients referred for small bowel capsule endoscopy for obscure gastrointestinal bleeding. Endoscopies were independently reviewed in FICE1 and white light; findings were then reviewed by another researcher, establishing a gold standard. Diagnostic yield was defined as the presence of lesions with high bleeding potential (P2) angioectasias, ulcers or tumours. Diagnostic yield using FICE1 was significantly higher than white light (55% vs. 42%, p=0.021). A superior number of P2 lesions was detected with FICE1 (74 vs. 44, p=0.003), particularly angioectasias (54 vs. 26, p=0.002), but not ulcers or tumours. FICE1 was significantly superior to white light, resulting in a 13% improvement in diagnostic yield, and potentially bleeding lesions particularly angioectasias were more often observed. Our results support the use of FICE1 while reviewing small bowel capsule endoscopy for obscure gastrointestinal bleeding. Copyright © 2015 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.

Half of the Most Luminous Quasars May Be Obscured: Investigating the Nature of WISE-Selected Hot Dust-Obscured Galaxies

NASA Astrophysics Data System (ADS)

Assef, R. J.; Eisenhardt, P. R. M.; Stern, D.; Tsai, C.-W.; Wu, J.; Wylezalek, D.; Blain, A. W.; Bridge, C. R.; Donoso, E.; Gonzales, A.; Griffith, R. L.; Jarrett, T. H.

2015-05-01

The Wide-field Infrared Survey Explorer mission has unveiled a rare population of high-redshift (z = 1-4.6), dusty, hyper-luminous galaxies, with infrared luminosities {{L}IR}\\gt {{10}13} {{L}⊙ }, and sometimes exceeding {{10}14} {{L}⊙ }. Previous work has shown that their dust temperatures and overall far-infrared spectral energy distributions (SEDs) are significantly hotter than expected to be powered by star formation. We present here an analysis of the rest-frame optical through mid-infrared SEDs for a large sample of these so-called “hot, dust-obscured galaxies” (Hot DOGs). We find that the SEDs of Hot DOGs are generally well modeled by the combination of a luminous, yet obscured active galactic nuclei (AGNs) that dominates the rest-frame emission at λ \\gt 1 μ m and the bolometric luminosity output, and a less luminous host galaxy that is responsible for the bulk of the rest optical/UV emission. Even though the stellar mass of the host galaxies may be as large as 1011-1012 M⊙, the AGN emission, with a range of luminosities comparable to those of the most luminous QSOs known, require that either Hot DOGs have black hole masses significantly in excess of the local relations, or that they radiate significantly above the Eddington limit, at a level at least 10 times more efficiently than z ˜ 2 QSOs. We show that, while rare, the number density of Hot DOGs is comparable to that of equally luminous but unobscured (i.e., Type 1) QSOs. This may be at odds with the trend suggested at lower luminosities for the fraction of obscured AGNs to decrease with increasing luminosity. That trend may, instead, reverse at higher luminosities. Alternatively, Hot DOGs may not be the torus-obscured counterparts of the known optically selected, largely unobscured, hyper-luminous QSOs, and may represent a new component of the galaxy evolution paradigm. Finally, we discuss the environments of Hot DOGs and statistically show that these objects are in regions as dense as those of known high-redshift proto-clusters.

Erratum: "Space Density of Optically Selected Type 2 Quasars" (2008, AJ, 136, 2373)

NASA Astrophysics Data System (ADS)

Reyes, Reinabelle; Zakamska, Nadia L.; Strauss, Michael A.; Green, Joshua; Krolik, Julian H.; Shen, Yue; Richards, Gordon T.; Anderson, Scott F.; Schneider, Donald P.

2010-03-01

Figure 12 of the paper "Space Density of Optically Selected Type 2 Quasars" compares the obscured quasar fractions derived in our work with those of other studies. Unfortunately, some of the points from these other studies were shown incorrectly. Specifically, the results from X-ray data—Hasinger (2004; open circles) and Ueda et al. (2003; open squares)—which we had taken from Figure 16 of Hopkins et al. (2006), were affected by a luminosity conversion error, in the sense that the displayed luminosities for these data were too high by ~1 dex. With this erratum, we correct this problem and update the figure. The new version (Figure 12) shows more recent results from Hasinger (2008), in lieu of the Hasinger (2004) data points. These are based on data in the redshift range z = 0.2-3.2 (open circles) in that work. The best linear fit to these data (black dashed line) is consistent with that derived for the redshift slice z = 0.4-0.8, which overlaps with the highest redshift bin in our study, and is higher than that derived for redshifts smaller than 0.4 (corresponding to a shift of ~0.7 dex in luminosity). Figure 12 also shows estimates of the obscured quasar fraction derived from the ratio of IR to bolometric luminosities of an AGN sample at redshift z ~ 1 (Treister et al. 2008; filled triangles). Because the obscured quasar fractions derived from our analysis (colored arrows) are strict lower limits, there was already a hint in the previous version of Figure 12 that at high quasar luminosities, we find higher obscured quasar fractions than X-ray surveys. The correction and updates of Figure 12 strengthen this conclusion. At face value, our derived obscured quasar fractions are consistent with those from IR data (Treister et al. 2008; filled triangles). However, we find that they are significantly higher than those derived from X-ray surveys at L_[O\\,\\mathsc {iii]}\\gtrsim 10^{9.5}\\;L_{\\odot }, especially those from the recent analysis by Hasinger (2008). This comparison strongly suggests that optical selection successfully identifies a population of luminous obscured quasars that are missed by X-ray selection.

Orbiter "Enterprise" rides "piggy-back" atop NASA 747 carrier

NASA Image and Video Library

1977-09-23

S77-28649 (23 Sept 1977) --- The shuttle Orbiter 101 "Enterprise" sits atop the NASA 747 carrier aircraft in a piggy-back configuration prior to separation for the third free flight of the Shuttle Approach and Landing Tests (ALT) conducted on September 23, 1977, at the Dryden Flight Research Center (DFRC) in Southern California. The crew of the "enterprise" consisted of astronauts Fred W. Haise Jr., commander, and C. Gordon Fullerton, pilot. This photo was shot from one of the T-38 chase planes accompanying the ALT craft. Three other T-38 chase planes are pictured.

Role of Conserved Oligomeric Golgi Complex in the Abnormalities of Glycoprotein Processing in Breast Cancer Cells

DTIC Science & Technology

2006-05-01

terminal oligosaccharide units serve as highly specific biological recognition molecules implicated in major regulatory processes of the cell...treatment or mock-treated for 9 days. To study the glycosylation process in COG complex depleted cells series of Pulse -Chase experiments have been...DAMD17-03-1-0243 TITLE: Role of the Conserved Oligomeric Golgi Complex in the Abnormalities of Glycoprotein Processing in Breast Cancer

Bunyaviridae and Their Replication. Part 2. Replication of Bunyaviridae

DTIC Science & Technology

1990-01-01

Ivatt RJ. Synthesis and processing of asparagine- mulates intracellularly: cellular process of the large glycopro- linked oligosaccharides . Anna Rev...the high-mannose rather than complex type, and no evidence for the presence of 0-linked oligosaccharides A- has been obtained (86,87,93,120,146). AA ’U...and Pulse -chase experiments revealed no precursor/prod- G2 has not been identified. However, an intergenic uct relationship between the 78- and 14-kd

Energy and Process Optimization and Benchmarking of Army Industrial Processes

DTIC Science & Technology

2006-09-01

casting is a metal part formed by pouring molten iron, steel, aluminum, zinc , titanium, magnesium, copper, brass, bronze or cobalt, in nearly all...blanketing techniques. The loss of high-priced alloys is also mini- mized, while slag or dross rates are cut in half to help decrease disposal costs...fabricated of iron and steel; hot dip coating such items with aluminum, lead, or zinc ; retin- ning cans and utensils; (3) engraving, chasing and

Identifying Luminous AGN in Deep Surveys: Revised IRAC Selection Criteria

NASA Astrophysics Data System (ADS)

Donley, Jennifer; Koekemoer, A. M.; Brusa, M.; Capak, P.; Cardamone, C. N.; Civano, F.; Ilbert, O.; Impey, C. D.; Kartaltepe, J.; Miyaji, T.; Salvato, M.; Sanders, D. B.; Trump, J. R.; Zamorani, G.

2012-01-01

Spitzer IRAC selection is a powerful tool for identifying luminous AGN. The AGN selection wedges currently in use, however, are heavily contaminated by star-forming galaxies, especially at high redshift. Using the large samples of luminous AGN and high-redshift star-forming galaxies in COSMOS, we redefine the AGN selection criteria for use in deep IRAC surveys. The new IRAC criteria are designed to be both highly complete and reliable, and incorporate the best aspects of the current AGN selection wedges and of infrared power-law selection while excluding high redshift star-forming galaxies selected via the BzK, DRG, LBG, and SMG criteria. At QSO-luminosities of log L(2-10 keV)>44, the new IRAC criteria recover 75% of the hard X-ray and IRAC-detected XMM-COSMOS sample, yet only 37% of the IRAC AGN candidates have X-ray counterparts, a fraction that rises to 51% in regions with Chandra exposures of 50-160 ks. X-ray stacking of the individually X-ray non-detected AGN candidates leads to a hard X-ray signal indicative of heavily obscured to mildly Compton-thick obscuration (log NH >= 23.7). While IRAC selection recovers a substantial fraction of luminous unobscured and obscured AGN, it is incomplete to low-luminosity and host-dominated AGN.

En route noise levels from propfan test assessment airplane

NASA Technical Reports Server (NTRS)

Garber, Donald P.; Willshire, William L., Jr.

1994-01-01

The en route noise test was designed to characterize propagation of propfan noise from cruise altitudes to the ground. In-flight measurements of propfan source levels and directional patterns were made by a chase plane flying in formation with the propfan test assessment (PTA) airplane. Ground noise measurements were taken during repeated flights over a distributed microphone array. The microphone array on the ground was used to provide ensemble-averaged estimates of mean flyover noise levels, establish confidence limits for those means, and measure propagation-induced noise variability. Even for identical nominal cruise conditions, peak sound levels for individual overflights varied substantially about the average, particularly when overflights were performed on different days. Large day-to-day variations in peak level measurements appeared to be caused by large day-to-day differences in propagation conditions and tended to obscure small variations arising from operating conditions. A parametric evaluation of the sensitivity of this prediction method to weather measurement and source level uncertainties was also performed. In general, predictions showed good agreement with measurements. However, the method was unable to predict short-term variability of ensemble-averaged data within individual overflights. Although variations in absorption appear to be the dominant factor in variations of peak sound levels recorded on the ground, accurate predictions of those levels require that a complete description of operational conditions be taken into account. The comprehensive and integrated methods presented in this paper have adequately predicted ground-measured sound levels. On average, peak sound levels were predicted within 3 dB for each of the three different cruise conditions.

Energetics and evasion dynamics of large predators and prey: pumas vs. hounds.

PubMed

Bryce, Caleb M; Wilmers, Christopher C; Williams, Terrie M

2017-01-01

Quantification of fine-scale movement, performance, and energetics of hunting by large carnivores is critical for understanding the physiological underpinnings of trophic interactions. This is particularly challenging for wide-ranging terrestrial canid and felid predators, which can each affect ecosystem structure through distinct hunting modes. To compare free-ranging pursuit and escape performance from group-hunting and solitary predators in unprecedented detail, we calibrated and deployed accelerometer-GPS collars during predator-prey chase sequences using packs of hound dogs ( Canis lupus familiaris , 26 kg, n  = 4-5 per chase) pursuing simultaneously instrumented solitary pumas ( Puma concolor , 60 kg, n  = 2). We then reconstructed chase paths, speed and turning angle profiles, and energy demands for hounds and pumas to examine performance and physiological constraints associated with cursorial and cryptic hunting modes, respectively. Interaction dynamics revealed how pumas successfully utilized terrain (e.g., fleeing up steep, wooded hillsides) as well as evasive maneuvers (e.g., jumping into trees, running in figure-8 patterns) to increase their escape distance from the overall faster hounds (avg. 2.3× faster). These adaptive strategies were essential to evasion in light of the mean 1.6× higher mass-specific energetic costs of the chase for pumas compared to hounds (mean: 0.76 vs. 1.29 kJ kg -1  min -1 , respectively). On an instantaneous basis, escapes were more costly for pumas, requiring exercise at ≥90% of predicted [Formula: see text] and consuming as much energy per minute as approximately 5 min of active hunting. Our results demonstrate the marked investment of energy for evasion by a large, solitary carnivore and the advantage of dynamic maneuvers to postpone being overtaken by group-hunting canids.

Global Average Brightness Temperature for April 2003

NASA Image and Video Library

2003-06-02

This image shows average temperatures in April, 2003, observed by AIRS at an infrared wavelength that senses either the Earth's surface or any intervening cloud. Similar to a photograph of the planet taken with the camera shutter held open for a month, stationary features are captured while those obscured by moving clouds are blurred. Many continental features stand out boldly, such as our planet's vast deserts, and India, now at the end of its long, clear dry season. Also obvious are the high, cold Tibetan plateau to the north of India, and the mountains of North America. The band of yellow encircling the planet's equator is the Intertropical Convergence Zone (ITCZ), a region of persistent thunderstorms and associated high, cold clouds. The ITCZ merges with the monsoon systems of Africa and South America. Higher latitudes are increasingly obscured by clouds, though some features like the Great Lakes, the British Isles and Korea are apparent. The highest latitudes of Europe and Eurasia are completely obscured by clouds, while Antarctica stands out cold and clear at the bottom of the image. http://photojournal.jpl.nasa.gov/catalog/PIA00427

The use of a high resolution model in a private environment.

NASA Astrophysics Data System (ADS)

van Dijke, D.; Malda, D.

2009-09-01

The commercial organisation MeteoGroup uses high resolution modelling for multiple purposes. MeteoGroup uses the Weather Research and Forecasting Model (WRF®1). WRF is used in the operational environment of several MeteoGroup companies across Europe. It is also used in hindcast studies, for example hurricane tracking, wind climate computation and deriving boundary conditions for air quality models. A special operational service was set up for our tornado chasing team that uses high resolution flexible WRF data to chase for super cells and tornados in the USA during spring. Much effort is put into the development and improvement of the pre- and post-processing of the model. At MeteoGroup the static land-use data has been extended and adjusted to improve temperature and wind forecasts. The system has been modified such that sigma level input data from the global ECMWF model can be used for initialisation. By default only pressure level data could be used. During the spin-up of the model synoptical observations are nudged. A program to adjust possible initialisation errors of several surface parameters in coastal areas has been implemented. We developed an algorithm that computes cloud fractions using multiple direct model output variables. Forecasters prefer to use weather codes for their daily forecasts to detect severe weather. For this usage we developed model weather codes using a variety of direct model output and our own derived variables. 1 WRF® is a registered trademark of the University Corporation for Atmospheric Research (UCAR)

Obscured Black Hole Growth at High Redshift and High Luminosity

NASA Astrophysics Data System (ADS)

Urry, C. Megan

We propose to complete the census of cosmic black hole growth by measuring luminous and/or distant quasars using Spitzer, Herschel, Chandra and XMM-Newton imaging in Stripe 82 the deepest Sloan Digital Sky Survey field, and now the premier legacy field among 100 deg2 survey areas. These extensive ancillary data offer unsurpassed sensitivity to accreting supermassive black holes in luminous quasars out to z 6, including obscured objects missed by optical/UV surveys. We address six science goals centered on the growth of supermassive black holes: 1) We will constrain the mass accreted in luminous quasars by determining the evolving luminosity function of high-luminosity X-ray-selected AGN, including obscured quasars, especially at high redshift, where previous surveys have limited statistics. 2) We will build a comprehensive multi-wavelength population synthesis model that describes cosmic black hole accretion across most of the history of the Universe, constrained by the wealth of data now available. This will be the first population synthesis model that is constrained at high luminosity and high redshift (courtesy of Stripe 82X). 3) We will characterize the spectral energy distributions (SEDs) of luminous X-ray selected quasars, including obscured ones. We will assess the dust content in the host galaxies and diagnose the relative contributions of black hole fueling and star formation, using Herschel data to probe the cold molecular gas from which stars form and comparing X-rays from accretion onto the central black hole. We will also use high-quality optical imaging to disentangle nuclear from host galaxy emission in a representative sub-sample of quasars. 4) Using Spitzer, Herschel, Chandra, XMM-Newton, and optical data, we will identify candidates for the most heavily obscured black holes, which we will follow up with ground-based IR spectroscopy using Keck and Palomar (to which Yale has guaranteed access). In this way we will recover obscured AGN missed by optical surveys, mitigating optical biases in quasar demography. 5) We will investigate the large-scale environments of quasars, in which black holes appear to acquire at least half of their mass, by studying the clustering of AGN in Stripe 82. Specifically, we will measure the halo occupation distribution, which is the probability of a dark matter halo of a given mass to host central and satellite AGN above a given luminosity. We will assess whether rapid black hole growth depends on halo mass, and how the average halo mass in which AGN occur might depend on AGN or galaxy properties. For this analysis, the hundreds of luminous quasars at z>2 in Stripe 82X and its high redshift completeness (92%) are particularly important. 6) We will investigate early black hole growth at z>6 by analyzing fluctuations in the infrared and X-ray backgrounds (i.e., below source detection levels). Specifically, we will directly correlate the Spitzer-measured cosmic infrared background (CIB) and the cosmic X-ray background (CXB) measured with XMM-Newton, on roughly 20 times larger scales than previous studies. This offers the best probe of early BH growth until high-sensitivity X-ray observatories like Athena and Lynx. These studies will determine how much mass is accreted in the most luminous and/or obscured quasars, and how the energy released into galaxies depends on key variables such as redshift, AGN luminosity, Eddington ratio and wavelength. This accurate, data validated estimate of the radiation deposited into host galaxies is essential for incorporating feedback into models of galaxy evolution. The Stripe 82X survey, as the richest multiwavelength survey covering >30 deg2 of the sky, deep enough in X-rays to see luminous quasars out to z 10, will yield many important discoveries, ideally including unexpected ones found by others in the community.

Tools for Protecting the Privacy of Specific Individuals in Video

NASA Astrophysics Data System (ADS)

Chen, Datong; Chang, Yi; Yan, Rong; Yang, Jie

2007-12-01

This paper presents a system for protecting the privacy of specific individuals in video recordings. We address the following two problems: automatic people identification with limited labeled data, and human body obscuring with preserved structure and motion information. In order to address the first problem, we propose a new discriminative learning algorithm to improve people identification accuracy using limited training data labeled from the original video and imperfect pairwise constraints labeled from face obscured video data. We employ a robust face detection and tracking algorithm to obscure human faces in the video. Our experiments in a nursing home environment show that the system can obtain a high accuracy of people identification using limited labeled data and noisy pairwise constraints. The study result indicates that human subjects can perform reasonably well in labeling pairwise constraints with the face masked data. For the second problem, we propose a novel method of body obscuring, which removes the appearance information of the people while preserving rich structure and motion information. The proposed approach provides a way to minimize the risk of exposing the identities of the protected people while maximizing the use of the captured data for activity/behavior analysis.

Hot Dust Obscured Galaxies with Excess Blue Light: Dual AGN or Single AGN Under Extreme Conditions?

NASA Astrophysics Data System (ADS)

Assef, R. J.; Walton, D. J.; Brightman, M.; Stern, D.; Alexander, D.; Bauer, F.; Blain, A. W.; Diaz-Santos, T.; Eisenhardt, P. R. M.; Finkelstein, S. L.; Hickox, R. C.; Tsai, C.-W.; Wu, J. W.

2016-03-01

Hot dust-obscured galaxies (Hot DOGs) are a population of hyper-luminous infrared galaxies identified by the Wide-field Infrared Survey Explorer (WISE) mission from their very red mid-IR colors, and characterized by hot dust temperatures (T > 60 K). Several studies have shown clear evidence that the IR emission in these objects is powered by a highly dust-obscured active galactic nucleus (AGN) that shows close to Compton-thick absorption at X-ray wavelengths. Thanks to the high AGN obscuration, the host galaxy is easily observable, and has UV/optical colors usually consistent with those of a normal galaxy. Here we discuss a sub-population of eight Hot DOGs that show enhanced rest-frame UV/optical emission. We discuss three scenarios that might explain the excess UV emission: (I) unobscured light leaked from the AGN by reflection over the dust or by partial coverage of the accretion disk; (II) a second unobscured AGN in the system; or (III) a luminous young starburst. X-ray observations can help discriminate between these scenarios. We study in detail the blue excess Hot DOG WISE J020446.13-050640.8, which was serendipitously observed by Chandra/ACIS-I for 174.5 ks. The X-ray spectrum is consistent with a single, hyper-luminous, highly absorbed AGN, and is strongly inconsistent with the presence of a secondary unobscured AGN. Based on this, we argue that the excess blue emission in this object is most likely either due to reflection or a co-eval starburst. We favor the reflection scenario as the unobscured star formation rate needed to power the UV/optical emission would be ≳1000 M⊙ yr-1. Deep polarimetry observations could confirm the reflection hypothesis.

HOT DUST OBSCURED GALAXIES WITH EXCESS BLUE LIGHT: DUAL AGN OR SINGLE AGN UNDER EXTREME CONDITIONS?

DOE Office of Scientific and Technical Information (OSTI.GOV)

Assef, R. J.; Diaz-Santos, T.; Walton, D. J.

Hot dust-obscured galaxies (Hot DOGs) are a population of hyper-luminous infrared galaxies identified by the Wide-field Infrared Survey Explorer (WISE) mission from their very red mid-IR colors, and characterized by hot dust temperatures (T > 60 K). Several studies have shown clear evidence that the IR emission in these objects is powered by a highly dust-obscured active galactic nucleus (AGN) that shows close to Compton-thick absorption at X-ray wavelengths. Thanks to the high AGN obscuration, the host galaxy is easily observable, and has UV/optical colors usually consistent with those of a normal galaxy. Here we discuss a sub-population of eight Hot DOGsmore » that show enhanced rest-frame UV/optical emission. We discuss three scenarios that might explain the excess UV emission: (i) unobscured light leaked from the AGN by reflection over the dust or by partial coverage of the accretion disk; (ii) a second unobscured AGN in the system; or (iii) a luminous young starburst. X-ray observations can help discriminate between these scenarios. We study in detail the blue excess Hot DOG WISE J020446.13–050640.8, which was serendipitously observed by Chandra/ACIS-I for 174.5 ks. The X-ray spectrum is consistent with a single, hyper-luminous, highly absorbed AGN, and is strongly inconsistent with the presence of a secondary unobscured AGN. Based on this, we argue that the excess blue emission in this object is most likely either due to reflection or a co-eval starburst. We favor the reflection scenario as the unobscured star formation rate needed to power the UV/optical emission would be ≳1000 M{sub ⊙} yr{sup −1}. Deep polarimetry observations could confirm the reflection hypothesis.« less

Gambling Harm and Crime Careers.

PubMed

May-Chahal, Corinne; Humphreys, Leslie; Clifton, Alison; Francis, Brian; Reith, Gerda

2017-03-01

Incarcerated populations across the world have been found to be consistently and significantly more vulnerable to problem gambling than general populations in the same countries. In an effort to gain a more specific understanding of this vulnerability the present study applied latent class analysis and criminal career theory to gambling data collected from a sample of English and Scottish, male and female prisoners (N = 1057). Theoretical links between gambling and crime were tested through three hypotheses: (1) that prisoners in the UK would have higher rates of problem gambling behaviour than the national population; (2) that if the link between gambling and crime is coincidental, gambling behaviour would be highly prevalent in an offending population, and (3) if connections between gambling behaviour and offending are co-symptomatic a mediating factor would show a strong association. The first of these was supported, the second was not supported and the third was partially supported. Latent class analysis found six gambling behaviour clusters measured by responses to the Problem Gambling Severity Index, primarily distinguished by loss chasing behaviour. Longitudinal offending data drawn from the Police National Computer database found four criminal career types, distinguished by frequency and persistence over time. A significant association was found between higher level loss chasing and high rate offending in criminal careers suggesting that impulse control may be a mediating factor for both gambling harm and criminal careers.

Wars of the holographic world

NASA Astrophysics Data System (ADS)

Preskill, John

2008-12-01

In the popular imagination, the iconic American theoretical physicist is Richard Feynman, in all his safe-cracking, bongo-thumping, woman-chasing glory. I suspect that many physicists, if asked to name a living colleague who best captures the spirit of Feynman, would give the same answer as me: Leonard Susskind. As far as I know, Susskind does not crack safes, thump bongos, or chase women, yet he shares Feynman's brash cockiness (which in Susskind's case is leavened by occasional redeeming flashes of self-deprecation) and Feynman's gift for spinning fascinating anecdotes. If you are having a group of physicists over for dinner and want to be sure to have a good time, invite Susskind.

Pilot Ed Lewis with T-34C aircraft on ramp

NASA Image and Video Library

1998-03-04

NASA pilot Ed Lewis with the T-34C aircraft on the Dryden Flight Research Center Ramp. The aircraft was previously used at the Lewis Research Center in propulsion experiments involving turboprop engines, and was used as a chase aircraft at Dryden for smaller and slower research projects. Chase aircraft accompany research flights for photography and video purposes, and also as support for safety and research. At Dryden, the T-34 is used mainly for smaller remotely piloted vehicles which fly slower than NASA's F-18's, used for larger scale projects. This aircraft was returned to the U.S. Navy in May of 2002.

Inhibition of processing of plant N-linked oligosaccharides by castanospermine.

PubMed

Hori, H; Pan, Y T; Molyneux, R J; Elbein, A D

1984-02-01

Castanospermine (1,6,7,8-tetrahydroxyoctahydroindolizine) is a plant alkaloid that inhibits lysosomal alpha- and beta-glucosidase. It also inhibits processing of influenza viral glycoproteins by inhibiting glucosidase I and leads to altered glycoproteins with Glc3Man7GlcNAc2 structures. Castanospermine was tested as an inhibitor of glycoprotein processing in suspension-cultured soybean cells. Soybean cells were pulse-labeled with [2-3H]mannose and chased for varying periods in unlabeled medium. In normal cells, the initial glycopeptides contained oligosaccharides having Glc3Man9GlcNAc2 to Glc1Man9GlcNAc2 structures and these were trimmed during the chase to Man9GlcNac2 to Man7GlcNAc2 structures. In the presence of castanospermine, no trimming of glucose residues occurred although some mannose residues were apparently still removed. Thus, the major oligosaccharide in the glycopeptides of castanospermine-incubated cells after a 90-min chase was a Glc3Man7GlcNAc2 structure. Smaller amounts of Glc3Man6GlcNAc2 and Glc3Man5GlcNAc2 were also identified. Thus, in plant cells, castanospermine also prevents the removal of the outermost glucose residue.

Dynamic properties of chasers in a moving queue based on a delayed chasing model

NASA Astrophysics Data System (ADS)

Ning, Guo; Jian-Xun, Ding; Xiang, Ling; Qin, Shi; Reinhart, Kühne

2016-05-01

A delayed chasing model is proposed to simulate the chase behavior in the queue, where each member regards the closest one ahead as the target, and the leader is attracted to a target point with slight fluctuation. When the initial distances between neighbors possess an identical low value, the fluctuating target of the leader can cause an amplified disturbance in the queue. After a long period of time, the queue recovers the stable state from the disturbance, forming a straight-line-like pattern again, but distances between neighbors grow. Whether the queue can keep stable or not depends on initial distance, desired velocity, and relaxation time. Furthermore, we carry out convergence analysis to explain the divergence transformation behavior and confirm the convergence conditions, which is in approximate agreement with simulations. Project supported by the National Natural Science Foundation of China (Grant Nos. 71071044, 71001001, 71201041, and 11247291), the Doctoral Program of the Ministry of Education of China (Grant Nos. 20110111120023 and 20120111120022), the Postdoctoral Fund Project of China (Grant No. 2013M530295), the National Basic Research Program of China (Grant No. 2012CB725404), and 1000 Plan for Foreign Talent, China (Grant No. WQ20123400070).

Steering a virtual blowfly: simulation of visual pursuit.

PubMed

Boeddeker, Norbert; Egelhaaf, Martin

2003-09-22

The behavioural repertoire of male flies includes visually guided chasing after moving targets. The visuomotor control system for these pursuits belongs to the fastest found in the animal kingdom. We simulated a virtual fly, to test whether or not experimentally established hypotheses on the underlying control system are sufficient to explain chasing behaviour. Two operating instructions for steering the chasing virtual fly were derived from behavioural experiments: (i) the retinal size of the target controls the fly's forward speed and, thus, indirectly its distance to the target; and (ii) a smooth pursuit system uses the retinal position of the target to regulate the fly's flight direction. Low-pass filters implement neuronal processing time. Treating the virtual fly as a point mass, its kinematics are modelled in consideration of the effects of translatory inertia and air friction. Despite its simplicity, the model shows behaviour similar to that of real flies. Depending on its starting position and orientation as well as on target size and speed, the virtual fly either catches the target or follows it indefinitely without capture. These two behavioural modes of the virtual fly emerge from the control system for flight steering without implementation of an explicit decision maker.

Design of the LBNF Beamline Target Station

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tariq, S.; Ammigan, K.; Anderson, K.

2016-10-01

The Long Baseline Neutrino Facility (LBNF) project will build a beamline located at Fermilab to create and aim an intense neutrino beam of appropriate energy range toward the DUNE detectors at the SURF facility in Lead, South Dakota. Neutrino production starts in the Target Station, which consists of a solid target, magnetic focusing horns, and the associated sub-systems and shielding infrastructure. Protons hit the target producing mesons which are then focused by the horns into a helium-filled decay pipe where they decay into muons and neutrinos. The target and horns are encased in actively cooled steel and concrete shielding inmore » a chamber called the target chase. The reference design chase is filled with air, but nitrogen and helium are being evaluated as alternatives. A replaceable beam window separates the decay pipe from the target chase. The facility is designed for initial operation at 1.2 MW, with the ability to upgrade to 2.4 MW, and is taking advantage of the experience gained by operating Fermilab’s NuMI facility. We discuss here the design status, associated challenges, and ongoing R&D and physics-driven component optimization of the Target Station.« less

A Novel Pulse-Chase Paradigm to Visualize the Trafficking of Transport Vesicles in Neurons

NASA Astrophysics Data System (ADS)

Al-Bassam, Sarmad

In neurons transmembrane proteins are targeted to dendrites in vesicles that traffic solely within the somatodendritic compartment. How these vesicles are retained within the somatodendritic domain is unknown. Here we adapt a novel pulse chase system that allows synchronous release of exogenous transmembrane proteins from the endoplasmic reticulum using FKBP12 and Rapamycin. We demonstrate proof-of-concept and establish protein trafficking controls in incremental steps. We demonstrate the utility of this approach in studying protein trafficking and establish parameters for analysis of time-lapse images. We implement this novel pulse-chase strategy to track the movements of post-Golgi transport vesicles. Surprisingly, we found that post-Golgi vesicles carrying dendritic proteins were equally likely to enter axons and dendrites. However, once such vesicles entered the axon they very rarely moved beyond the axon initial segment, but instead either halted or reversed direction in an actin and Myosin Va-dependent manner. In contrast, vesicles carrying either an axonal or a nonspecifically localized protein only rarely halted or reversed and instead generally proceeded to the distal axon. Thus, our results are consistent with the axon initial segment behaving as a vesicle filter that mediates the differential trafficking of transport vesicles.

Tiger beetles pursue prey using a proportional control law with a delay of one half-stride.

PubMed

Haselsteiner, Andreas F; Gilbert, Cole; Wang, Z Jane

2014-06-06

Tiger beetles are fast diurnal predators capable of chasing prey under closed-loop visual guidance. We investigated this control system using statistical analyses of high-speed digital recordings of beetles chasing a moving prey dummy in a laboratory arena. Correlation analyses reveal that the beetle uses a proportional control law in which the angular position of the prey relative to the beetle's body axis drives the beetle's angular velocity with a delay of about 28 ms. The proportionality coefficient or system gain, 12 s(-1), is just below critical damping. Pursuit simulations using the derived control law predict angular orientation during pursuits with a residual error of about 7°. This is of the same order of magnitude as the oscillation imposed by the beetle's alternating tripod gait, which was not factored into the control law. The system delay of 28 ms equals a half-stride period, i.e. the time between the touch down of alternating tripods. Based on these results, we propose a physical interpretation of the observed control law: to turn towards its prey, the beetle on average exerts a sideways force proportional to the angular position of the prey measured a half-stride earlier.

The Built Environment Is a Microbial Wasteland

PubMed Central

2016-01-01

ABSTRACT Humanity’s transition from the outdoor environment to the built environment (BE) has reduced our exposure to microbial diversity. The relative importance of factors that contribute to the composition of human-dominated BE microbial communities remains largely unknown. In their article in this issue, Chase and colleagues (J. Chase, J. Fouquier, M. Zare, D. L. Sonderegger, R. Knight, S. T. Kelley, J. Siegel, and J. G. Caporaso, mSystems 1(2):e00022-16, 2016, http://dx.doi.org/10.1128/mSystems.00022-16) present an office building study in which they controlled for environmental factors, geography, surface material, sampling location, and human interaction type. They found that surface location and geography were the strongest factors contributing to microbial community structure, while surface material had little effect. Even in the absence of direct human interaction, BE surfaces were composed of 25 to 30% human skin-associated taxa. The authors demonstrate how technical variation across sequencing runs is a major issue, especially in BE work, where the biomass is often low and the potential for PCR contaminants is high. Overall, the authors conclude that BE surfaces are desert-like environments where microbes passively accumulate. PMID:27832216

Optimizing performance of hybrid FSO/RF networks in realistic dynamic scenarios

NASA Astrophysics Data System (ADS)

Llorca, Jaime; Desai, Aniket; Baskaran, Eswaran; Milner, Stuart; Davis, Christopher

2005-08-01

Hybrid Free Space Optical (FSO) and Radio Frequency (RF) networks promise highly available wireless broadband connectivity and quality of service (QoS), particularly suitable for emerging network applications involving extremely high data rate transmissions such as high quality video-on-demand and real-time surveillance. FSO links are prone to atmospheric obscuration (fog, clouds, snow, etc) and are difficult to align over long distances due the use of narrow laser beams and the effect of atmospheric turbulence. These problems can be mitigated by using adjunct directional RF links, which provide backup connectivity. In this paper, methodologies for modeling and simulation of hybrid FSO/RF networks are described. Individual link propagation models are derived using scattering theory, as well as experimental measurements. MATLAB is used to generate realistic atmospheric obscuration scenarios, including moving cloud layers at different altitudes. These scenarios are then imported into a network simulator (OPNET) to emulate mobile hybrid FSO/RF networks. This framework allows accurate analysis of the effects of node mobility, atmospheric obscuration and traffic demands on network performance, and precise evaluation of topology reconfiguration algorithms as they react to dynamic changes in the network. Results show how topology reconfiguration algorithms, together with enhancements to TCP/IP protocols which reduce the network response time, enable the network to rapidly detect and act upon link state changes in highly dynamic environments, ensuring optimized network performance and availability.

Surface Modified TiO2 Obscurants for Increased Safety and Performance

DTIC Science & Technology

2012-11-01

based obscurant devices in performance. 15. SUBJECT TERMS Obscurant, visible, IR , smoke, TiO2, aerosol, particle, surface modification...hexamethyldimethoxysilane IR Infrared wavelength LabRAM Lab scale Resonant Acoustic Mixer from Resodyn Corporation LPM Liters Per Minute M106 Currently fielded (Army...trinitrophloroglucinol UV-Vis Ultraviolet-visible wavelengths KEYWORDS Obscurant, visible, IR , smoke, TiO2, aerosol, particle, surface modification

Pulse-chase Analysis of N-linked Sugar Chains from Glycoproteins in Mammalian Cells

PubMed Central

Avezov, Edward; Ron, Efrat; Izenshtein, Yana; Adan, Yosef; Lederkremer, Gerardo Z.

2010-01-01

Attachment of the Glc3Man9GlcNAc2 precursor oligosaccharide to nascent polypeptides in the ER is a common modification for secretory proteins. Although this modification was implicated in several biological processes, additional aspects of its function are emerging, with recent evidence of its role in the production of signals for glycoprotein quality control and trafficking. Thus, phenomena related to N-linked glycans and their processing are being intensively investigated. Methods that have been recently developed for proteomic analysis have greatly improved the characterization of glycoprotein N-linked glycans. Nevertheless, they do not provide insight into the dynamics of the sugar chain processing involved. For this, labeling and pulse-chase analysis protocols are used that are usually complex and give very low yields. We describe here a simple method for the isolation and analysis of metabolically labeled N-linked oligosaccharides. The protocol is based on labeling of cells with [2-3H] mannose, denaturing lysis and enzymatic release of the oligosaccharides from either a specifically immunoprecipitated protein of interest or from the general glycoprotein pool by sequential treatments with endo H and N-glycosidase F, followed by molecular filtration (Amicon). In this method the isolated oligosaccharides serve as an input for HPLC analysis, which allows discrimination between various glycan structures according to the number of monosaccharide units comprising them, with a resolution of a single monosaccharide. Using this method we were able to study high mannose N-linked oligosaccharide profiles of total cell glycoproteins after pulse-chase in normal conditions and under proteasome inhibition. These profiles were compared to those obtained from an immunoprecipitated ER-associated degradation (ERAD) substrate. Our results suggest that most NIH 3T3 cellular glycoproteins are relatively stable and that most of their oligosaccharides are trimmed to Man9-8GlcNAc2. In contrast, unstable ERAD substrates are trimmed to Man6-5GlcNAc2 and glycoproteins bearing these species accumulate upon inhibition of proteasomal degradation. PMID:20424595

Pulse-chase analysis of N-linked sugar chains from glycoproteins in mammalian cells.

PubMed

Avezov, Edward; Ron, Efrat; Izenshtein, Yana; Adan, Yosef; Lederkremer, Gerardo Z

2010-04-27

Attachment of the Glc3Man9GlcNAc2 precursor oligosaccharide to nascent polypeptides in the ER is a common modification for secretory proteins. Although this modification was implicated in several biological processes, additional aspects of its function are emerging, with recent evidence of its role in the production of signals for glycoprotein quality control and trafficking. Thus, phenomena related to N-linked glycans and their processing are being intensively investigated. Methods that have been recently developed for proteomic analysis have greatly improved the characterization of glycoprotein N-linked glycans. Nevertheless, they do not provide insight into the dynamics of the sugar chain processing involved. For this, labeling and pulse-chase analysis protocols are used that are usually complex and give very low yields. We describe here a simple method for the isolation and analysis of metabolically labeled N-linked oligosaccharides. The protocol is based on labeling of cells with [2-(3)H] mannose, denaturing lysis and enzymatic release of the oligosaccharides from either a specifically immunoprecipitated protein of interest or from the general glycoprotein pool by sequential treatments with endo H and N-glycosidase F, followed by molecular filtration (Amicon). In this method the isolated oligosaccharides serve as an input for HPLC analysis, which allows discrimination between various glycan structures according to the number of monosaccharide units comprising them, with a resolution of a single monosaccharide. Using this method we were able to study high mannose N-linked oligosaccharide profiles of total cell glycoproteins after pulse-chase in normal conditions and under proteasome inhibition. These profiles were compared to those obtained from an immunoprecipitated ER-associated degradation (ERAD) substrate. Our results suggest that most NIH 3T3 cellular glycoproteins are relatively stable and that most of their oligosaccharides are trimmed to Man9-8GlcNAc2. In contrast, unstable ERAD substrates are trimmed to Man6-5GlcNAc2 and glycoproteins bearing these species accumulate upon inhibition of proteasomal degradation.

Black carbon, particle number concentration and nitrogen oxide emission factors of random in-use vehicles measured with the on-road chasing method

NASA Astrophysics Data System (ADS)

Ježek, I.; Katrašnik, T.; Westerdahl, D.; Močnik, G.

2015-06-01

The chasing method was used in an on-road measurement campaign, and emission factors (EF) of black carbon (BC), particle number (PN) and nitrogen oxides (NOx) were determined for 139 individual vehicles of different types encountered on the roads. The aggregated results provide EFs for BC, NOx and PN for three vehicle categories: goods vehicles, gasoline and diesel passenger cars. This is the first on-road measurement study where BC EFs of numerous individual diesel cars were determined in real-world driving conditions. We found good agreement between EFs of goods vehicles determined in this campaign and the results of previous studies that used either chasing or remote sensing measurement techniques. The composition of the sampled car fleet determined from the national vehicle registry information is reflective of Eurostat statistical data on the Slovenian and European vehicle fleet. The median BC EF of diesel and gasoline cars that were in use for less than 5 years, decreased by 60 and 47% from those in use for 5-10 years, respectively, the median NOx and PN EFs, of goods vehicles that were in use for less than five years, decreased from those in use for 5-10 years by 52 and 67%, respectively. The influence of engine maximum power of the measured EFs showed an increase in NOx EF from least to more powerful vehicles with diesel engines. Finally a disproportionate contribution of high emitters to the total emissions of the measured fleet was found; the top 25% of emitting diesel cars contributed 63, 47 and 61% of BC, NOx and PN emissions respectively. With the combination of relatively simple on-road measurements with sophisticated post processing individual vehicles EF can be determined and useful information about the fleet emissions can be obtained by exactly representing vehicles which contribute disproportionally to vehicle fleet emissions; and monitor how the numerous emission reduction approaches are reflected in on-road driving conditions.

Genetic and isotope ratio mass spectrometric evidence for the occurrence of starch degradation and cycling in illuminated Arabidopsis leaves

PubMed Central

Baslam, Marouane; Baroja-Fernández, Edurne; Ricarte-Bermejo, Adriana; Sánchez-López, Ángela María; Aranjuelo, Iker; Bahaji, Abdellatif; Muñoz, Francisco José; Almagro, Goizeder; Pujol, Pablo; Galarza, Regina; Teixidor, Pilar; Pozueta-Romero, Javier

2017-01-01

Although there is a great wealth of data supporting the occurrence of simultaneous synthesis and breakdown of storage carbohydrate in many organisms, previous 13CO2 pulse-chase based studies indicated that starch degradation does not operate in illuminated Arabidopsis leaves. Here we show that leaves of gwd, sex4, bam4, bam1/bam3 and amy3/isa3/lda starch breakdown mutants accumulate higher levels of starch than wild type (WT) leaves when cultured under continuous light (CL) conditions. We also show that leaves of CL grown dpe1 plants impaired in the plastidic disproportionating enzyme accumulate higher levels of maltotriose than WT leaves, the overall data providing evidence for the occurrence of extensive starch degradation in illuminated leaves. Moreover, we show that leaves of CL grown mex1/pglct plants impaired in the chloroplastic maltose and glucose transporters display a severe dwarf phenotype and accumulate high levels of maltose, strongly indicating that the MEX1 and pGlcT transporters are involved in the export of starch breakdown products to the cytosol to support growth during illumination. To investigate whether starch breakdown products can be recycled back to starch during illumination through a mechanism involving ADP-glucose pyrophosphorylase (AGP) we conducted kinetic analyses of the stable isotope carbon composition (δ13C) in starch of leaves of 13CO2 pulsed-chased WT and AGP lacking aps1 plants. Notably, the rate of increase of δ13C in starch of aps1 leaves during the pulse was exceedingly higher than that of WT leaves. Furthermore, δ13C decline in starch of aps1 leaves during the chase was much faster than that of WT leaves, which provides strong evidence for the occurrence of AGP-mediated cycling of starch breakdown products in illuminated Arabidopsis leaves. PMID:28152100

Versatile Boron Carbide-Based Visual Obscurant Compositions for Smoke Munitions

DTIC Science & Technology

2015-04-17

Versatile Boron Carbide-Based Visual Obscurant Compositions for Smoke Munitions Anthony P. Shaw,*,† Giancarlo Diviacchi,‡ Ernest L. Black,‡ Jared D...have been demonstrated to produce thick white smoke clouds upon combustion. These compositions use powdered boron carbide (B4C) as a pyrotechnic...ignition and are safe to handle. KEYWORDS: Smoke, Obscurants, Pyrotechnics, Boron carbide, Sustainable chemistry ■ INTRODUCTION Visible obscuration

Are Compton-thick AGNs the Missing Link between Mergers and Black Hole Growth?

NASA Astrophysics Data System (ADS)

Kocevski, Dale D.; Brightman, Murray; Nandra, Kirpal; Koekemoer, Anton M.; Salvato, Mara; Aird, James; Bell, Eric F.; Hsu, Li-Ting; Kartaltepe, Jeyhan S.; Koo, David C.; Lotz, Jennifer M.; McIntosh, Daniel H.; Mozena, Mark; Rosario, David; Trump, Jonathan R.

2015-12-01

We examine the host morphologies of heavily obscured active galactic nuclei (AGNs) at z∼ 1 to test whether obscured super-massive black hole growth at this epoch is preferentially linked to galaxy mergers. Our sample consists of 154 obscured AGNs with {N}{{H}}\\gt {10}23.5 {{cm}}-2 and z\\lt 1.5. Using visual classifications, we compare the morphologies of these AGNs to control samples of moderately obscured (1022 cm{}-2\\lt {N}{{H}}\\lt {10}23.5 {{cm}}-2) and unobscured ({N}{{H}}\\lt {10}22 {{cm}}-2) AGN. These control AGNs have similar redshifts and intrinsic X-ray luminosities to our heavily obscured AGN. We find that heavily obscured AGNs are twice as likely to be hosted by late-type galaxies relative to unobscured AGNs ({65.3}-4.6+4.1% versus {34.5}-2.7+2.9%) and three times as likely to exhibit merger or interaction signatures ({21.5}-3.3+4.2% versus {7.8}-1.3+1.9%). The increased merger fraction is significant at the 3.8σ level. If we exclude all point sources and consider only extended hosts, we find that the correlation between the merger fraction and obscuration is still evident, although at a reduced statistical significance (2.5σ ). The fact that we observe a different disk/spheroid fraction versus obscuration indicates that the viewing angle cannot be the only thing differentiating our three AGN samples, as a simple unification model would suggest. The increased fraction of disturbed morphologies with obscuration supports an evolutionary scenario, in which Compton-thick AGNs are a distinct phase of obscured super-massive black hole (SMBH) growth following a merger/interaction event. Our findings also suggest that some of the merger-triggered SMBH growth predicted by recent AGN fueling models may be hidden among the heavily obscured, Compton-thick population.

Understanding the build-up of SMBH and Galaxies

NASA Astrophysics Data System (ADS)

Carrera, Francisco; Georgakakis, Antonis; Ueda, Yoshihiro; Akylas, Thanassis; Lanzuisi, Giorgio; Castello, N.

2015-09-01

One of the main open questions in modern Astrophysics is understanding the coupled growth of supermassive black holes by accretion and their host galaxies via star formation, from their peak at redshifts z~ 1-4 to the present time. The generic scenario proposed involves an early phase of intense black hole growth that takes place behind large obscuring columns of inflowing dust and gas clouds. It is postulated that this is followed by a blow-out stage during which some form of AGN feedback controls the fate of the interstellar medium and hence, the evolution of the galaxy. X-rays are essential for testing this scenario as they uniquely probe AGN at both the early heavily obscured stage and the later blow-out phase. X-ray spectral analysis can identify the smoking gun evidence of heavily obscured black hole growth (e.g. intense iron Kalpha line). It therefore provides the most robust method for compiling clean samples of deeply shrouded AGN with well-defined selection functions and unbiased determinations of their intrinsic properties (accretion luminosity, obscuring column). X-rays are also the best window for studying in detail AGN feedback. This process ultimately originates in the innermost regions close to the supermassive black hole and is dominated, in terms of energy and mass flux, by highly ionised material that remains invisible at other wavelengths. The most important epoch for investigating the relation between AGN and galaxies is the redshift range z~1-4, when most black holes and stars we see in the present-day Universe were put in place. Unfortunately, exhaustive efforts with current high-energy telescopes only scrape the tip of the iceberg of the most obscured AGN population. Moreover, Xray studies of the incidence, nature and energetics of AGN feedback are limited to the local Universe. The Athena observatory will provide the technological leap required for a breakthrough in our understanding of AGN and galaxy evolution at the heyday of the Universe. The excellent survey capabilities of Athena/WFI (effective area, angular resolution, field of view) will allow to measure the incidence of feedback in the shape of warm absorbers and Ultra Fast Outflows among the general population of AGN, as well as to complete the census of black hole growth by detecting and characterising significant samples of the most heavily obscured (including Compton thick) AGN, to redshifts z~3-4. The outstanding spectral throughput and resolution of Athena/X-IFU will permit measuring the energetics of those outflows to assess their influence on their host galaxies. The demographics of the heavily obscured and outflowing populations relative to their hosts are fundamental for understanding how major black hole growth events relate to the build-up of galaxies.

Understanding the build-up of supermassive black holes and galaxies

NASA Astrophysics Data System (ADS)

Carrera, Francisco; Ueda, Yoshihiro; Georgakakis, Antonis

2016-07-01

One of the main open questions in modern Astrophysics is understanding the coupled growth of supermassive black holes by accretion and their host galaxies via star formation, from their peak at redshifts z~ 1-4 to the present time. The generic scenario proposed involves an early phase of intense black hole growth that takes place behind large obscuring columns of inflowing dust and gas clouds. It is postulated that this is followed by a blow-out stage during which some form of AGN feedback controls the fate of the interstellar medium and hence, the evolution of the galaxy. X-rays are essential for testing this scenario as they uniquely probe AGN at both the early heavily obscured stage and the later blow-out phase. X-ray spectral analysis can identify the smoking gun evidence of heavily obscured black hole growth (e.g. intense iron Kalpha line). It therefore provides the most robust method for compiling clean samples of deeply shrouded AGN with well-defined selection functions and unbiased determinations of their intrinsic properties (accretion luminosity, obscuring column). X-rays are also the best window for studying in detail AGN feedback. This process ultimately originates in the innermost regions close to the supermassive black hole and is dominated, in terms of energy and mass flux, by highly ionisedmaterial that remains invisible at other wavelengths. The most important epoch for investigating the relation between AGN and galaxies is the redshift range z~1-4, when most black holes and stars we see in the present-day Universe were put in place. Unfortunately, exhaustive efforts with current high-energy telescopes only scrape the tip of the iceberg of the most obscured AGN population. Moreover, Xray studies of the incidence, nature and energetics of AGN feedback are limited to the local Universe. The Athena observatory will provide the technological leap required for a breakthrough in our understanding of AGN and galaxy evolution at the heyday of the Universe. The excellent survey capabilities of Athena/WFI (effective area, angular resolution, field of view) will allow to measure the incidence of feedback in the shape of warm absorbers and Ultra Fast Outflows among the general population of AGN, as well as to complete the census of black hole growth by detecting and characterising significant samples of the most heavily obscured (including Compton thick) AGN, to redshifts z~3-4. The outstanding spectral throughput and resolution of Athena/X-IFU will permit measuring the energetics of those outflows to assess their influence on their host galaxies. The demographics of the heavily obscured and outflowing populations relative to their hosts are fundamental for understanding how major black hole growth events relate to the build-up of galaxies.

NASA HS3 Global Hawk on the Wing

NASA Image and Video Library

2013-08-30

The NASA Wallops T-34 chase aircraft intercepted Global Hawk 872 on its descent to runway 28 at NASA's Wallops Flight Facility in Wallops Island, Va. This photo of the Global Hawk was taken from the chase plane after finishing its third science flight. For more information about NASA's HS3 mission, visit: www.nasa.gov/HS3 Credit: NASA/ Brea Reeves NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

The Chase to Capture Gamma Ray Bursts

NASA Technical Reports Server (NTRS)

Gehrels, Neil

2008-01-01

Gamma-ray bursts are the most powerful explosions in the universe, thought to be the birth cries of black holes. It has taken 40 years of international cooperation and competition to begin to unravel the mystery of their origin. The most recent chapter in this field is being written by the SWIFT mission, a fast-response satellite with 3 power telescopes. An international team from countries all over the world participates in the chase to capture the fading light of bursts detected by SWIFT. This talk will discuss the challenges and excitement of building this space observatory. New results will be presented on our growing understanding of exploding stars and fiery mergers of orbiting stars.

Effect of Clouds on Optical Imaging of the Space Shuttle During the Ascent Phase: A Statistical Analysis Based on a 3D Model

NASA Technical Reports Server (NTRS)

Short, David A.; Lane, Robert E., Jr.; Winters, Katherine A.; Madura, John T.

2004-01-01

Clouds are highly effective in obscuring optical images of the Space Shuttle taken during its ascent by ground-based and airborne tracking cameras. Because the imagery is used for quick-look and post-flight engineering analysis, the Columbia Accident Investigation Board (CAIB) recommended the return-to-flight effort include an upgrade of the imaging system to enable it to obtain at least three useful views of the Shuttle from lift-off to at least solid rocket booster (SRB) separation (NASA 2003). The lifetimes of individual cloud elements capable of obscuring optical views of the Shuttle are typically 20 minutes or less. Therefore, accurately observing and forecasting cloud obscuration over an extended network of cameras poses an unprecedented challenge for the current state of observational and modeling techniques. In addition, even the best numerical simulations based on real observations will never reach "truth." In order to quantify the risk that clouds would obscure optical imagery of the Shuttle, a 3D model to calculate probabilistic risk was developed. The model was used to estimate the ability of a network of optical imaging cameras to obtain at least N simultaneous views of the Shuttle from lift-off to SRB separation in the presence of an idealized, randomized cloud field.

Geometrically Thick Obscuration by Radiation-driven Outflow from Magnetized Tori of Active Galactic Nuclei

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chan, Chi-Ho; Krolik, Julian H.

2017-07-01

Near-Eddington radiation from active galactic nuclei (AGNs) has significant dynamical influence on the surrounding dusty gas, plausibly furnishing AGNs with geometrically thick obscuration. We investigate this paradigm with radiative magnetohydrodynamics simulations. The simulations solve the magnetohydrodynamics equations simultaneously with the infrared (IR) and ultraviolet (UV) radiative transfer (RT) equations; no approximate closure is used for RT. We find that our torus, when given a suitable sub-Keplerian angular momentum profile, spontaneously evolves toward a state in which its opening angle, density distribution, and flow pattern change only slowly. This “steady” state lasts for as long as there is gas resupply towardmore » the inner edge. The torus is best described as a midplane inflow and a high-latitude outflow. The outflow is launched from the torus inner edge by UV radiation and expands in solid angle as it ascends; IR radiation continues to drive the wide-angle outflow outside the central hole. The dusty outflow obscures the central source in soft X-rays, the IR, and the UV over three-quarters of solid angle, and each decade in column density covers roughly equal solid angle around the central source; these obscuration properties are similar to what observations imply.« less

Handling target obscuration through Markov chain observations

NASA Astrophysics Data System (ADS)

Kouritzin, Michael A.; Wu, Biao

2008-04-01

Target Obscuration, including foliage or building obscuration of ground targets and landscape or horizon obscuration of airborne targets, plagues many real world filtering problems. In particular, ground moving target identification Doppler radar, mounted on a surveillance aircraft or unattended airborne vehicle, is used to detect motion consistent with targets of interest. However, these targets try to obscure themselves (at least partially) by, for example, traveling along the edge of a forest or around buildings. This has the effect of creating random blockages in the Doppler radar image that move dynamically and somewhat randomly through this image. Herein, we address tracking problems with target obscuration by building memory into the observations, eschewing the usual corrupted, distorted partial measurement assumptions of filtering in favor of dynamic Markov chain assumptions. In particular, we assume the observations are a Markov chain whose transition probabilities depend upon the signal. The state of the observation Markov chain attempts to depict the current obscuration and the Markov chain dynamics are used to handle the evolution of the partially obscured radar image. Modifications of the classical filtering equations that allow observation memory (in the form of a Markov chain) are given. We use particle filters to estimate the position of the moving targets. Moreover, positive proof-of-concept simulations are included.

Characterization of the OPAL LiDAR under controlled obscurant conditions

NASA Astrophysics Data System (ADS)

Cao, Xiaoying; Church, Philip; Matheson, Justin

2016-05-01

Neptec Technologies' OPAL-120 3D LiDAR is optimized for obscurant penetration. The OPAL-120 uses a scanning mechanism based on the Risley prism pair. The scan patterns are created by rotating two prisms under independent motor control. The geometry and material properties of the prisms define the conical field-of-view of the sensor, which can be built to between 60 to 120 degrees. The OPAL-120 was recently evaluated using a controlled obscurant chamber capable of generating clouds of obscurants over a depth of 22m. Obscurants used in this investigation include: Arizona road dust, water fog, and fog-oil. The obscurant cloud optical densities were monitored with a transmissometer. Optical depths values ranged from an upper value of 6 and progressively decreased to 0. Targets were positioned at the back of the obscurant chamber at a distance of 60m from the LiDAR. The targets are made of a foreground array of equally spaced painted wood stripes in front of a solid background. Reflectivity contrasts were achieved with foreground/background combinations of white/white, white/black and black/white. Data analysis will be presented on the effect of optical densities on range and cross-range resolution, and accuracy. The analysis includes the combinations of all obscurant types and target reflectivity contrasts.

Imaging Complex Protein Metabolism in Live Organisms by Stimulated Raman Scattering Microscopy with Isotope Labeling

PubMed Central

2016-01-01

Protein metabolism, consisting of both synthesis and degradation, is highly complex, playing an indispensable regulatory role throughout physiological and pathological processes. Over recent decades, extensive efforts, using approaches such as autoradiography, mass spectrometry, and fluorescence microscopy, have been devoted to the study of protein metabolism. However, noninvasive and global visualization of protein metabolism has proven to be highly challenging, especially in live systems. Recently, stimulated Raman scattering (SRS) microscopy coupled with metabolic labeling of deuterated amino acids (D-AAs) was demonstrated for use in imaging newly synthesized proteins in cultured cell lines. Herein, we significantly generalize this notion to develop a comprehensive labeling and imaging platform for live visualization of complex protein metabolism, including synthesis, degradation, and pulse–chase analysis of two temporally defined populations. First, the deuterium labeling efficiency was optimized, allowing time-lapse imaging of protein synthesis dynamics within individual live cells with high spatial–temporal resolution. Second, by tracking the methyl group (CH3) distribution attributed to pre-existing proteins, this platform also enables us to map protein degradation inside live cells. Third, using two subsets of structurally and spectroscopically distinct D-AAs, we achieved two-color pulse–chase imaging, as demonstrated by observing aggregate formation of mutant hungtingtin proteins. Finally, going beyond simple cell lines, we demonstrated the imaging ability of protein synthesis in brain tissues, zebrafish, and mice in vivo. Hence, the presented labeling and imaging platform would be a valuable tool to study complex protein metabolism with high sensitivity, resolution, and biocompatibility for a broad spectrum of systems ranging from cells to model animals and possibly to humans. PMID:25560305

Digital data sets that describe aquifer characteristics of the Central Oklahoma Aquifer in central Oklahoma

USGS Publications Warehouse

Runkle, D.L.; Christenson, S.C.; Rea, Alan

1997-01-01

ARC/INFO export files The data sets in this report include digitized aquifer boundaries and maps of hydraulic conductivity, recharge, and ground-water level elevation contours for the Central Oklahoma aquifer in central Oklahoma. This area encompasses all or part of Cleveland, Lincoln, Logan, Oklahoma, Payne, and Pottawatomie Counties. The Central Oklahoma aquifer includes the alluvial and terrace deposits along major streams, the Garber Sandstone and Wellington Formations, and the Chase, Council Grove, and Admire Groups. The Quaternary-age alluvial and terrace deposits consist of unconsolidated clay, silt, sand, and gravel. The Permian-age Garber Sandstone and Wellington Formations consist of sandstone with interbedded siltstone and mudstone. The Permian-age Chase, Council Grove, and Admire Groups consist of sandstone, shale, and thin limestone. The Central Oklahoma aquifer underlies about 3,000 square miles of central Oklahoma where the aquifer is used extensively for municipal, industrial, commercial, and domestic water supplies. Most of the usable ground water within the aquifer is from the Garber Sandstone and Wellington Formations. Substantial quantities of usable ground water also are present in the Chase, Council Grove, and Admire Groups, and in alluvial and terrace deposits associated with the major streams. The aquifer boundaries, hydraulic conductivity and recharge values, and ground-water level elevation contours are from previously published reports.

Real-time measurements of nitrogen oxide emissions from in-use New York City transit buses using a chase vehicle.

PubMed

Shorter, Joanne H; Herndon, Scott; Zahniser, Mark S; Nelson, David D; Wormhoudt, Joda; Demerjian, Kenneth L; Kolb, Charles E

2005-10-15

New diesel engine technologies and alternative fuel engines are being introduced into fleets of mass transit buses to try to meet stricter emission regulations of nitrogen oxides and particulates: Real-time instruments including an Aerodyne Research tunable infrared laser differential absorption spectrometer (TILDAS) were deployed in a mobile laboratory to assess the impact of the implementation of the new technologies on nitrogen oxide emissions in real world driving conditions. Using a "chase" vehicle sampling strategy, the mobile laboratory followed target vehicles, repeatedly sampling their exhaust. Nitrogen oxides from approximately 170 in-use New York City mass transit buses were sampled during the field campaigns. Emissions from conventional diesel buses, diesel buses with continuously regenerating technology (CRT), diesel hybrid electric buses, and compressed natural gas (CNG) buses were compared. The chase vehicle sampling method yields real world emissions that can be included in more realistic emission inventories. The NO, emissions from the diesel and CNG buses were comparable. The hybrid electric buses had approximately one-half the NOx emissions. In CRT diesels, NO2 accounts for about one-third of the NOx emitted in the exhaust, while for non-CRT buses the NO2 fraction is less than 10%.

Effect of Transitioning from Standard Reference Material 2806a to Standard Reference Material 2806b for Light Obscuration Particle Countering

DTIC Science & Technology

2016-04-01

Reference Material 2806b for Light Obscuration Particle Countering April 2016 UNCLASSIFIED UNCLASSIFIED Joel Schmitigal 27809 Standard Form 298 (Rev...Standard Reference Material 2806b for Light Obscuration Particle Countering 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6...Reference Material 2806a to Standard Reference Material 2806b for Light Obscuration Particle Countering Joel Schmitigal Force Projection

Detection of BrdU-label Retaining Cells in the Lacrimal Gland: Implications for Tissue Repair

PubMed Central

You, Samantha; Tariq, Ayesha; Kublin, Claire L.; Zoukhri, Driss

2011-01-01

The purpose of the present study was to determine if the lacrimal gland contains 5-bromo-2’-deoxyuridine (BrdU)-label retaining cells and if they are involved in tissue repair. Animals were pulsed daily with BrdU injections for 7 consecutive days. After a chase period of 2, 4, or 12 weeks, the animals were sacrificed and the lacrimal glands were removed and processed for BrdU immunostaining. In another series of experiments, the lacrimal glands of 12-week chased animals were either left untreated or were injected with interleukin 1 (IL-1) to induce injury. Two and half day post-injection, the lacrimal glands were removed and processed for BrdU immunostaining. After 2 and 4 week of chase period, a substantial number of lacrimal gland cells were BrdU+ (11.98 ± 1.84 and 7.95 ± 1.83 BrdU+ cells/mm2, respectively). After 12 weeks of chase, there was a 97% decline in the number of BrdU+ cells (0.38 ± 0.06 BrdU+ cells/mm2), suggesting that these BrdU-label retaining cells may represent slow-cycling adult stem/progenitor cells. In support of this hypothesis, the number of BrdU labeled cells increased over 7-fold during repair of the lacrimal gland (control: 0.41 ± 0.09 BrdU+ cells/mm2, injured: 2.91 ± 0.62 BrdU+ cells/mm2). Furthermore, during repair, among BrdU+ cells 58.2 ± 3.6 % were acinar cells, 26.4 ± 4.1% were myoepithelial cells, 0.4 ± 0.4% were ductal cells, and 15.0 ± 3.0% were stromal cells. We conclude that the murine lacrimal gland contains BrdU-label retaining cells that are mobilized following injury to generate acinar, myoepithelial and ductal cells. PMID:22101331

Energetics and evasion dynamics of large predators and prey: pumas vs. hounds

PubMed Central

Wilmers, Christopher C.; Williams, Terrie M.

2017-01-01

Quantification of fine-scale movement, performance, and energetics of hunting by large carnivores is critical for understanding the physiological underpinnings of trophic interactions. This is particularly challenging for wide-ranging terrestrial canid and felid predators, which can each affect ecosystem structure through distinct hunting modes. To compare free-ranging pursuit and escape performance from group-hunting and solitary predators in unprecedented detail, we calibrated and deployed accelerometer-GPS collars during predator-prey chase sequences using packs of hound dogs (Canis lupus familiaris, 26 kg, n = 4–5 per chase) pursuing simultaneously instrumented solitary pumas (Puma concolor, 60 kg, n = 2). We then reconstructed chase paths, speed and turning angle profiles, and energy demands for hounds and pumas to examine performance and physiological constraints associated with cursorial and cryptic hunting modes, respectively. Interaction dynamics revealed how pumas successfully utilized terrain (e.g., fleeing up steep, wooded hillsides) as well as evasive maneuvers (e.g., jumping into trees, running in figure-8 patterns) to increase their escape distance from the overall faster hounds (avg. 2.3× faster). These adaptive strategies were essential to evasion in light of the mean 1.6× higher mass-specific energetic costs of the chase for pumas compared to hounds (mean: 0.76 vs. 1.29 kJ kg−1 min−1, respectively). On an instantaneous basis, escapes were more costly for pumas, requiring exercise at ≥90% of predicted \\documentclass[12pt]{minimal} \\usepackage{amsmath} \\usepackage{wasysym} \\usepackage{amsfonts} \\usepackage{amssymb} \\usepackage{amsbsy} \\usepackage{upgreek} \\usepackage{mathrsfs} \\setlength{\\oddsidemargin}{-69pt} \\begin{document} }{}$\\dot {\\mathrm{V }}{\\mathrm{O}}_{2\\mathrm{MAX}}$\\end{document}V ˙O2MAX and consuming as much energy per minute as approximately 5 min of active hunting. Our results demonstrate the marked investment of energy for evasion by a large, solitary carnivore and the advantage of dynamic maneuvers to postpone being overtaken by group-hunting canids. PMID:28828280

Pilots' Attention Distributions Between Chasing a Moving Target and a Stationary Target.

PubMed

Li, Wen-Chin; Yu, Chung-San; Braithwaite, Graham; Greaves, Matthew

2016-12-01

Attention plays a central role in cognitive processing; ineffective attention may induce accidents in flight operations. The objective of the current research was to examine military pilots' attention distributions between chasing a moving target and a stationary target. In the current research, 37 mission-ready F-16 pilots participated. Subjects' eye movements were collected by a portable head-mounted eye-tracker during tactical training in a flight simulator. The scenarios of chasing a moving target (air-to-air) and a stationary target (air-to-surface) consist of three operational phases: searching, aiming, and lock-on to the targets. The findings demonstrated significant differences in pilots' percentage of fixation during the searching phase between air-to-air (M = 37.57, SD = 5.72) and air-to-surface (M = 33.54, SD = 4.68). Fixation duration can indicate pilots' sustained attention to the trajectory of a dynamic target during air combat maneuvers. Aiming at the stationary target resulted in larger pupil size (M = 27,105, SD = 6565), reflecting higher cognitive loading than aiming at the dynamic target (M = 23,864, SD = 8762). Pilots' visual behavior is not only closely related to attention distribution, but also significantly associated with task characteristics. Military pilots demonstrated various visual scan patterns for searching and aiming at different types of targets based on the research settings of a flight simulator. The findings will facilitate system designers' understanding of military pilots' cognitive processes during tactical operations. They will assist human-centered interface design to improve pilots' situational awareness. The application of an eye-tracking device integrated with a flight simulator is a feasible and cost-effective intervention to improve the efficiency and safety of tactical training.Li W-C, Yu C-S, Braithwaite G, Greaves M. Pilots' attention distributions between chasing a moving target and a stationary target. Aerosp Med Hum Perform. 2016; 87(12):989-995.

Galaxy gas as obscurer - I. GRBs x-ray galaxies and find an NH3∝ M_{star} relation

NASA Astrophysics Data System (ADS)

Buchner, Johannes; Schulze, Steve; Bauer, Franz E.

2017-02-01

An important constraint for galaxy evolution models is how much gas resides in galaxies, in particular, at the peak of star formation z = 1-3. We attempt a novel approach by letting long-duration gamma ray bursts (LGRBs) x-ray their host galaxies and deliver column densities to us. This requires a good understanding of the obscurer and biases introduced by incomplete follow-up observations. We analyse the X-ray afterglow of all 844 Swift LGRBs to date for their column density NH. To derive the population properties, we propagate all uncertainties in a consistent Bayesian methodology. The NH distribution covers the 1020-23 cm-2 range and shows no evolutionary effect. Higher obscurations, e.g. Compton-thick columns, could have been detected but are not observed. The NH distribution is consistent with sources randomly populating a ellipsoidal gas cloud of major axis {N^{major}H }=10^{23}cm^{-2} with 0.22 dex intrinsic scatter between objects. The unbiased SHOALS survey of afterglows and hosts allows us to constrain the relation between Spitzer-derived stellar masses and X-ray derived column densities NH. We find a well-constrained power-law relation of NH = 1021.7 cm-2 × (M⋆/109.5 M⊙)1/3, with 0.5 dex intrinsic scatter between objects. The Milky Way and the Magellanic clouds also follow this relation. From the geometry of the obscurer, its stellar mass dependence and comparison with local galaxies, we conclude that LGRBs are primarily obscured by galaxy-scale gas. Ray tracing of simulated Illustris galaxies reveals a relation of the same normalization, but a steeper stellar-mass dependence and mild redshift evolution. Our new approach provides valuable insight into the gas residing in high-redshift galaxies.

DETECTION OF THE INTERMEDIATE-WIDTH EMISSION LINE REGION IN QUASAR OI 287 WITH THE BROAD EMISSION LINE REGION OBSCURED BY THE DUSTY TORUS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Li, Zhenzhen; Zhou, Hongyan; Wang, Huiyuan

2015-10-20

The existence of intermediate-width emission line regions (IELRs) in active galactic nuclei has been discussed for over two decades. A consensus, however, is yet to be arrived at due to the lack of convincing evidence for their detection. We present a detailed analysis of the broadband spectrophotometry of the partially obscured quasar OI 287. The ultraviolet intermediate-width emission lines (IELs) are very prominent, in high contrast to the corresponding broad emission lines (BELs) which are heavily suppressed by dust reddening. Assuming that the IELR is virialized, we estimated its distance to the central black hole to be ∼2.9 pc, similarmore » to the dust sublimation radius of ∼1.3 pc. Photo-ionization calculations suggest that the IELR has a hydrogen density of ∼10{sup 8.8}–10{sup 9.4} cm{sup −3}, within the range of values quoted for the dusty torus near the sublimation radius. Both its inferred location and physical conditions suggest that the IELR originates from the inner surface of the dusty torus. In the spectrum of this quasar, we identified only one narrow absorption-line system associated with the dusty material. With the aid of photo-ionization model calculations, we found that the obscuring material might originate from an outer region of the dusty torus. We speculate that the dusty torus, which is exposed to the central ionizing source, may produce IELs through photo-ionization processes, as well as obscure BELs as a natural “coronagraph.” Such a “coronagraph” could be found in a large number of partially obscured quasars and may be a useful tool to study IELRs.« less

The SCUBA-2 850 μm Follow-up of WISE-selected, Luminous Dust-obscured Quasars

NASA Astrophysics Data System (ADS)

Fan, Lulu; Jones, Suzy F.; Han, Yunkun; Knudsen, Kirsten K.

2017-12-01

Hot dust-obscured galaxies (Hot DOGs) are a new population recently discovered in the Wide-field Infrared Survey Explorer All-Sky survey. Multiwavelength follow-up observations suggest that they are luminous, dust-obscured quasars at high redshift. Here we present the JCMT SCUBA-2 850 μm follow-up observations of 10 Hot DOGs. Four out of ten Hot DOGs have been detected at >3σ level. Based on the IR SED decomposition approach, we derive the IR luminosities of AGN torus and cold dust components. Hot DOGs in our sample are extremely luminous with most of them having {L}{IR}{tot}> {10}14 {L}⊙ . The torus emissions dominate the total IR energy output. However, the cold dust contribution is still non-negligible, with the fraction of the cold dust contribution to the total IR luminosity (˜8%-24%) being dependent on the choice of torus model. The derived cold dust temperatures in Hot DOGs are comparable to those in UV bright quasars with similar IR luminosity, but much higher than those in SMGs. Higher dust temperatures in Hot DOGs may be due to the more intense radiation field caused by intense starburst and obscured AGN activities. Fourteen and five submillimeter serendipitous sources in the 10 SCUBA-2 fields around Hot DOGs have been detected at >3σ and >3.5σ levels, respectively. By estimating their cumulative number counts, we confirm the previous argument that Hot DOGs lie in dense environments. Our results support the scenario in which Hot DOGs are luminous, dust-obscured quasars lying in dense environments, and being in the transition phase between extreme starburst and UV-bright quasars.

In-situ roundness measurement and correction for pin journals in oscillating grinding machines

NASA Astrophysics Data System (ADS)

Yu, Hongxiang; Xu, Mengchen; Zhao, Jie

2015-01-01

In the mass production of vehicle-engine crankshafts, pin chasing grinding using oscillating grinding machines is a widely accepted method to achieve flexible and efficient performance. However, the eccentric movement of pin journals makes it difficult to develop an in-process roundness measurement scheme for the improvement of contour precision. Here, a new in-situ roundness measurement strategy is proposed with high scanning speed. The measuring mechanism is composed of a V-block and an adaptive telescopic support. The swing pattern of the telescopic support and the V-block is analysed for an equal angle-interval signal sampling. Hence roundness error signal is extracted in frequency domain using a small-signal model of the V-block roundness measurement method and the Fast Fourier Transformation. To implement the roundness data in the CNC coordinate system of an oscillating grinding machine, a transformation function is derived according to the motion model of pin chasing grinding methodology. Computer simulation reveals the relationship between the rotational position of the crankshaft component and the scanning angle of the displacement probe on the V-block, as well as the influence introduced by the rotation centre drift. Prototype investigation indicates the validity of the theoretical analysis and the feasibility of the new strategy.

Posttranslational modifications of Sindbis virus glycoproteins: electrophoretic analysis of pulse-chase-labeled infected cells.

PubMed

Bonatti, S; Cancedda, F D

1982-04-01

Cytoplasmic extracts prepared from Sindbis virus-infected chicken embryo fibroblasts pulse-chase-labeled with [35S]methionine 6 h postinfection were analyzed on a highly resolving sodium dodecyl sulfate-gel either directly or after various treatments. The results we obtained suggest that (i) the proteolytic cleavage which converts PE2 to E2 glycoprotein takes place intracellularly, before or at least during the formation of complex-type oligosaccharide side chains; and (ii) E1 glycoprotein undergoes a complex maturation pattern. Newly synthesized E1 has a molecular weight of 53,000: shortly thereafter, this 53,000 (53K) form was converted to a 50K form. Subsequently, the 50K form decreased its apparent molecular weight progressively and eventually comigrated with E1 glycoprotein present in the extracellular virus, which displays a molecular weight of 51,000 to 52,000. The conversion of the 53K to the 50K form was not the result of a proteolytic processing and did not depend on glycosylation or disulfide bridge formation and exchange. The possible mechanisms of this conversion are discussed. The second conversion step (from the 50K to the 51-52K form) was due to the formation of complex-type oligosaccharide and was reversed by incubating the cellular extracts with neuraminidase before electrophoretic analysis.

Biosynthesis and maturation of cellular membrane glycoproteins.

PubMed

Hunt, L A

1979-01-01

The biosynthesis and the processing of asparagine-linked oligosaccharides of cellular membrane glycoproteins were examined in monolayer cultures of BHK21 cells and human diploid fibroblasts after pulse- and pulse-chase labeling with [2-3H]mannose. After pronase digestion, radiolabeled glycopeptides were characterized by high-resolution gel filtration, with or without additional digestion with various exoglycosidases and endoglycosidases. Pulse-labeled glycoproteins contained a relatively homogenous population of neutral oligosaccharides (major species: Man9GlcNAc2ASN). The vast majority of these asparagine-linked oligosaccharides was smaller than the major fraction of lipid-linked oligosaccharides from the cell and was apparently devoid of terminal glucose. After pulse-chase or long labeling periods, a significant fraction of the large oligomannosyl cores was processed by removal of mannose units and addition of branch sugars (NeuNAc-Gal-GlcNAc), resulting in complex acidic structures containing three and possibly five mannoses. In addition, some of the large oligomannosyl cores were processed by the removal of only several mannoses, resulting in a mixture of neutral structures with 5-9 mannoses. This oligomannosyl core heterogeneity in both neutral and acidic oligosaccharides linked to asparagine in cellular membrane glycoproteins was analogous to the heterogeneity reported for the oligosaccharides of avian RNA tumor virus glycoproteins (Hunt LA, Wright SE, Etchison JR, Summers DF: J Virol 29:336, 1979).

Tiger beetles pursue prey using a proportional control law with a delay of one half-stride

PubMed Central

Haselsteiner, Andreas F.; Gilbert, Cole; Wang, Z. Jane

2014-01-01

Tiger beetles are fast diurnal predators capable of chasing prey under closed-loop visual guidance. We investigated this control system using statistical analyses of high-speed digital recordings of beetles chasing a moving prey dummy in a laboratory arena. Correlation analyses reveal that the beetle uses a proportional control law in which the angular position of the prey relative to the beetle's body axis drives the beetle's angular velocity with a delay of about 28 ms. The proportionality coefficient or system gain, 12 s−1, is just below critical damping. Pursuit simulations using the derived control law predict angular orientation during pursuits with a residual error of about 7°. This is of the same order of magnitude as the oscillation imposed by the beetle's alternating tripod gait, which was not factored into the control law. The system delay of 28 ms equals a half-stride period, i.e. the time between the touch down of alternating tripods. Based on these results, we propose a physical interpretation of the observed control law: to turn towards its prey, the beetle on average exerts a sideways force proportional to the angular position of the prey measured a half-stride earlier. PMID:24718454

76 FR 77593 - Proposed Exemptions From Certain Prohibited Transaction Restrictions

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-13

...This document contains notices of pendency before the Department of Labor (the Department) of proposed exemptions from certain of the prohibited transaction restrictions of the Employee Retirement Income Security Act of 1974 (ERISA or the Act) and/or the Internal Revenue Code of 1986 (the Code). This notice includes the following proposed exemptions: D-11517, JPMorgan Chase & Co. and its Current and Future Affiliates and Subsidiaries (JPMorgan Chase); D- 11579, Delaware Charter Guarantee & Trust Co. d\\b\\a\\ Principle Trust Company (Principle Trust); D-11628, Aztec Well Servicing Company and Related Companies Medical Plan Trust Fund (the Plan); D-11669, Genzyme Corporation 401(k) Plan (the Plan or the Applicant); and Retirement Program for Employees of EnPro Industries (the Plan), D-11662 et al.

Detection of ocean color changes from high altitudes

NASA Technical Reports Server (NTRS)

Hovis, W. A.; Forman, M. L.; Blaine, L. R.

1973-01-01

The detection of ocean color changes, thought to be due to chlorophyll concentrations and gelbstoffe variations, is attempted from high altitude (11.3km) and low altitude (0.3km). The atmospheric back scattering is shown to reduce contrast, but not sufficiently to obscure color change detection at high altitudes.

Readability of self-illuminated signs obscured by black fuel-fire smoke.

DOT National Transportation Integrated Search

1980-07-01

This study, using black fuel-fire generated smoke, is a partial replication of an earlier study using an inert white smoke as the obscuring agent in the study of the readability of smoke-obscured, self-illuminated emergency exit signs. : The results ...

Salmonid Whirling Disease

USGS Publications Warehouse

Markiw, Maria E.

1992-01-01

Whirling disease is a parasitic infection of trout and salmon by the myxosporean protozoan Myxobolus cerebralis (Syn. Myxosoma cerebralis). This parasite has selective tropism for cartilage; infection can cause deformities of the axial skeleton and neural damage that results in 'blacktail.' The disease is named for the erratic, tail-chasing, 'whirling' in young fish that are startled or fed. Heavy infection of young fish can result in high mortalities or unmarketable, deformed individuals. Although the parasite was first reported in 1903 in central Europe (Hofer 1903), its complete life cycle was not described until the early 1980's.

The Disk-Jet Connection in Radio-Loud AGN: The X-Ray Perspective

NASA Technical Reports Server (NTRS)

Sambruna, Rita

2008-01-01

Unification schemes assume that radio-loud active galactic nuclei (AGN) contain an accretion disk and a relativistic jet perpendicular to the disk, and an obscuring molecular torus. The jet dominance decreases with larger viewing angles from blazars to Broad-Line and Narrow-Line Radio Galaxies. A fundamental question is how accretion and ejecta are related. The X-rays provide a convenient window to study these issues, as they originate in the innermost nuclear regions and penetrate large obscuring columns. I review the data, using observations by Chandra but also from other currently operating high-energy experiments. Synergy with the upcoming GLAST mission will also be highlighted.

Environmental Effects on Compulsive Tail Chasing in Dogs

PubMed Central

Tiira, Katriina; Hakosalo, Osmo; Kareinen, Lauri; Thomas, Anne; Hielm-Björkman, Anna; Escriou, Catherine; Arnold, Paul; Lohi, Hannes

2012-01-01

Obsessive Compulsive Disorder (OCD) is a neuropsychiatric disorder observed both in humans and animals. Examples of Canine Compulsive Disorder (CD) include excessive tail chasing (TC), light/shadow chasing and flank sucking. We performed a questionnaire survey to investigate the characteristics of compulsive (TC) and its possible associations with environmental correlates and personality in a pet population of 368 dogs from four dog breeds. We observed an early onset of TC at 3–6 months of age and a large variation in TC frequency in all breeds, with an overrepresentation of milder cases. Almost half of the TC dogs showed lowered responsiveness during bouts and displayed also other types of compulsions more often than the controls. Interestingly, dogs that received dietary supplements, especially vitamins and minerals, expressed less TC compared to dogs that did not receive any supplements. Neutered females had less TC, suggesting an influence of ovarian hormones on TC. Tail chasers were shyer and had separated earlier from their mothers than the controls. Finally, our genetic study did not find an association between TC and CDH2, a locus previously associated with the canine flank sucking compulsion. In conclusion, the early-onset and the variable nature of the repetitive behaviour, which is affected by environmental factors such as micronutrients, neutering and maternal care, share several similar components between canine and human compulsions and supports canine TC as a model for human OCD. PMID:22844513

Cryptic sexual conflict in gift-giving insects: chasing the chase-away.

PubMed

Sakaluk, Scott K; Avery, Rachel L; Weddle, Carie B

2006-01-01

The chase-away model of sexual selection posits that elaborate male sexual displays arise because they exploit preexisting biases in females' sensory systems and induce females to mate in a suboptimal manner. An essential element of this hypothesis is that such manipulation should quickly lead to female resistance to male displays. Nuptial food gifts may be a frequent conduit by which males attempt to influence the mating behavior of females against females' own reproductive interests. In decorated crickets Gryllodes sigillatus, such inducements come in the form of a spermatophylax, a gelatinous mass forming part of the male's spermatophore and consumed by the female after mating. We conducted experiments in which spermatophylaxes obtained from male G. sigillatus were offered as novel food gifts to females of a non-gift-giving species (Acheta domesticus) having no evolutionary history of spermatophylax consumption. Female A. domesticus that were allowed to consume the spermatophylax took significantly longer to remate than when given no such opportunity. In contrast, when female G. sigillatus were prevented from consuming their partners' nuptial gifts, there was no difference in their propensity to remate relative to females permitted to consume a food gift after mating. These results suggest that the spermatophylax synthesized by male G. sigillatus contains substances designed to inhibit the sexual receptivity of their mates but that female G. sigillatus have evolved reduced responsiveness to these substances.

Development and testing of a prototype tool for integrated assessment of chemical status in marine environments.

PubMed

Andersen, Jesper H; Murray, Ciarán; Larsen, Martin M; Green, Norman; Høgåsen, Tore; Dahlgren, Elin; Garnaga-Budrė, Galina; Gustavson, Kim; Haarich, Michael; Kallenbach, Emilie M F; Mannio, Jaakko; Strand, Jakob; Korpinen, Samuli

2016-02-01

We report the development and application of a prototype tool for integrated assessment of chemical status in aquatic environments based on substance- and matrix-specific environmental assessment criteria (thresholds). The Chemical Status Assessment Tool (CHASE) integrates data on hazardous substances in water, sediments and biota as well as bio-effect indicators and is based on a substance- or bio-effect-specific calculation of a 'contamination ratio' being the ratio between an observed concentration and a threshold value. Values <1.0 indicate areas potentially 'unaffected', while values >1.0 indicate areas potentially 'affected'. These ratios are combined within matrices, i.e. for water, sediment and biota and for biological effects. The overall assessment used a 'one out, all out principle' with regard to each matrix. The CHASE tool was tested in the Baltic Sea and the North Sea in 376 assessment units. In the former, the chemical status was >1.0 in practically all areas indicating that all areas assessed were potentially affected. The North Sea included areas classified as unaffected or affected. The CHASE tool can in combination with temporal trend assessments of individual substances be advantageous for use in remedial action plans and, in particular, for the science-based evaluation of the status and for determining which specific substances are responsible for a status as potentially affected.

A minimal model of predator–swarm interactions

PubMed Central

Chen, Yuxin; Kolokolnikov, Theodore

2014-01-01

We propose a minimal model of predator–swarm interactions which captures many of the essential dynamics observed in nature. Different outcomes are observed depending on the predator strength. For a ‘weak’ predator, the swarm is able to escape the predator completely. As the strength is increased, the predator is able to catch up with the swarm as a whole, but the individual prey is able to escape by ‘confusing’ the predator: the prey forms a ring with the predator at the centre. For higher predator strength, complex chasing dynamics are observed which can become chaotic. For even higher strength, the predator is able to successfully capture the prey. Our model is simple enough to be amenable to a full mathematical analysis, which is used to predict the shape of the swarm as well as the resulting predator–prey dynamics as a function of model parameters. We show that, as the predator strength is increased, there is a transition (owing to a Hopf bifurcation) from confusion state to chasing dynamics, and we compute the threshold analytically. Our analysis indicates that the swarming behaviour is not helpful in avoiding the predator, suggesting that there are other reasons why the species may swarm. The complex shape of the swarm in our model during the chasing dynamics is similar to the shape of a flock of sheep avoiding a shepherd. PMID:24598204

A minimal model of predator-swarm interactions.

PubMed

Chen, Yuxin; Kolokolnikov, Theodore

2014-05-06

We propose a minimal model of predator-swarm interactions which captures many of the essential dynamics observed in nature. Different outcomes are observed depending on the predator strength. For a 'weak' predator, the swarm is able to escape the predator completely. As the strength is increased, the predator is able to catch up with the swarm as a whole, but the individual prey is able to escape by 'confusing' the predator: the prey forms a ring with the predator at the centre. For higher predator strength, complex chasing dynamics are observed which can become chaotic. For even higher strength, the predator is able to successfully capture the prey. Our model is simple enough to be amenable to a full mathematical analysis, which is used to predict the shape of the swarm as well as the resulting predator-prey dynamics as a function of model parameters. We show that, as the predator strength is increased, there is a transition (owing to a Hopf bifurcation) from confusion state to chasing dynamics, and we compute the threshold analytically. Our analysis indicates that the swarming behaviour is not helpful in avoiding the predator, suggesting that there are other reasons why the species may swarm. The complex shape of the swarm in our model during the chasing dynamics is similar to the shape of a flock of sheep avoiding a shepherd.

Biosynthetic processing of the oligosaccharide chains of cellular fibronectin.

PubMed

Olden, K; Hunter, V A; Yamada, K M

1980-10-15

We have examined the maturation or processing of the oligosaccharides of cellular fibronectin in cultured chick embryo fibroblasts. Fibronectin was pulse-labeled with [2-3H]mannose of [35S]methionine, and the turnover rates of carbohydrate and polypeptide portions of immunoprecipitated fibronectin were compared. The oligosaccharides on fibronectin were analyzed by gel electrophoresis for alterations in sensitivity to the enzyme endo-beta-N-acetylgluosaminidase H, which specifically cleaves the 'high-mannose' class of asparagine-linked oligosaccharide. Incorporated mannose was removed only at early time points, suggesting that the structure of fibronectin oligosaccharides was altered due to processing. This possibility was confirmed by the analysis of glycopeptides generated by exhaustive pronase digestion. Two major glycopeptide structures were detected; their properties correspond to a 'high-mannose' oligosaccharide precursor and a 'complex' carbohydrate product. The precursor-product relationship of these two forms of oligosaccharide chains was demonstrated by pulse-chase labeling experiments. The precursor glycopeptide had an apparent size (Mr 2100) comparable to (Man)9GlcNAc (Mr 2080), and was sensitive to endo-beta-N-acetylglucosaminidase H; nearly all of the labeled mannose incorporated in a 10 min pulse was released from fibronectin glycopeptides by this enzyme. During a 90 min chase period, the glycopeptides became larger and increasingly resistant to endo-beta-N-acetylglucosaminidase H cleavage. The final 'complex' or processed oligosaccharide structure contained approximately two-thirds less [3H]mannose, was insensitive to endo-beta-N-acetylglucosaminidase H and had an apparent Mr of 2300 as estimated by gel filtration. We conclude that the carbohydrate portion of fibronectin is synthesized as a 'high-mannose' intermediate and is subsequently processed to give the characteristic 'complex' oligosaccharide chains of fibronectin.

Jason Roadman | NREL

Science.gov Websites

using trained raptors, metrology, storm chasing, and wind tunnel testing of atmospheric turbulence. He Wind tunnel testing of atmospheric turbulence Education B.S. in Aerospace Engineering from Virginia

The [O III] Profiles of Infrared-selected Active Galactic Nuclei: More Powerful Outflows in the Obscured Population

NASA Astrophysics Data System (ADS)

DiPompeo, M. A.; Hickox, R. C.; Carroll, C. M.; Runnoe, J. C.; Mullaney, J. R.; Fischer, T. C.

2018-03-01

We explore the kinematics of ionized gas via the [O III] λ5007 emission lines in active galactic nuclei (AGNs) selected on the basis of their mid-infrared (IR) emission, and split into obscured and unobscured populations based on their optical‑IR colors. After correcting for differences in redshift distributions, we provide composite spectra of spectroscopically and photometrically defined obscured/Type 2 and unobscured/Type 1 AGNs from 3500 to 7000 Å. The IR-selected obscured sources contain a mixture of narrow-lined Type 2 AGNs and intermediate sources that have broad Hα emission and significantly narrower Hβ. Using both [O III] luminosities and AGN luminosities derived from optical‑IR spectral energy distribution fitting, we find evidence for enhanced large-scale obscuration in the obscured sources. In matched bins of luminosity we find that the obscured population typically has broader, more blueshifted [O III] emission than in the unobscured sample, suggestive of more powerful AGN-driven outflows. This trend is not seen in spectroscopically classified samples, and is unlikely to be entirely explained by orientation effects. In addition, outflow velocities increase from small to moderate AGN E(B ‑ V) values, before flattening out (as traced by FWHM) and even decreasing (as traced by blueshift). While difficult to fully interpret in a single physical model, due to both the averaging over populations and the spatially averaged spectra, these results agree with previous findings that simple geometric unification models are insufficient for the IR-selected AGN population, and may fit into an evolutionary model for obscured and unobscured AGNs.

Association of Regulatory Boards of Optometry

MedlinePlus

... Fraud contact number) or https://www.chase.com/credit-cards/customer-service . In addition, individuals may also consider reviewing their current credit reports at https://www.annualcreditreport.com/index.action . ...

Energetic cost of feeding territories in an Hawaiian honeycreeper.

PubMed

Carpenter, F Lynn; MacMillen, Richard E

1976-09-01

By analysis of time budgets the daily energy expenditure in territorial individuals of a Hawaiian honeycreeper (Vestiaria coccinea, Fam. Drepanididae) were estimated during the nonbreeding season and compared to that of nonterritorial individuals. The mean rise in living costs was 2.3 kcal/24 h or 17% of the nonterritorial energy budget. The most costly territorial behavior was advertisement rather than chasing, and total territorial cost was seen to be little affected by the number of intruders or the size of the territory. These results are compared with data on feeding (nonbreeding) territories of other nectar-feeding birds. The suggestion is made that hummingbirds may be more likely to develop nonbreeding territorial behavior in any set of environmental circumstances than are honeycreepers because of relatively lower total cost of advertisement plus chasing.

49 CFR 392.33 - Obscured lamps or reflective devices/material.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 5 2013-10-01 2013-10-01 false Obscured lamps or reflective devices/material. 392... REGULATIONS DRIVING OF COMMERCIAL MOTOR VEHICLES Use of Lighted Lamps and Reflectors § 392.33 Obscured lamps or reflective devices/material. (a) No commercial motor vehicle shall be driven when any of the lamps...

49 CFR 392.33 - Obscured lamps or reflective devices/material.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 5 2012-10-01 2012-10-01 false Obscured lamps or reflective devices/material. 392... REGULATIONS DRIVING OF COMMERCIAL MOTOR VEHICLES Use of Lighted Lamps and Reflectors § 392.33 Obscured lamps or reflective devices/material. (a) No commercial motor vehicle shall be driven when any of the lamps...

49 CFR 392.33 - Obscured lamps or reflective devices/material.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 49 Transportation 5 2014-10-01 2014-10-01 false Obscured lamps or reflective devices/material. 392... REGULATIONS DRIVING OF COMMERCIAL MOTOR VEHICLES Use of Lighted Lamps and Reflectors § 392.33 Obscured lamps or reflective devices/material. (a) No commercial motor vehicle shall be driven when any of the lamps...

49 CFR 392.33 - Obscured lamps or reflective devices/material.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 5 2011-10-01 2011-10-01 false Obscured lamps or reflective devices/material. 392... REGULATIONS DRIVING OF COMMERCIAL MOTOR VEHICLES Use of Lighted Lamps and Reflectors § 392.33 Obscured lamps or reflective devices/material. (a) No commercial motor vehicle shall be driven when any of the lamps...

A black hole nova obscured by an inner disk torus.

PubMed

Corral-Santana, J M; Casares, J; Muñoz-Darias, T; Rodríguez-Gil, P; Shahbaz, T; Torres, M A P; Zurita, C; Tyndall, A A

2013-03-01

Stellar-mass black holes (BHs) are mostly found in x-ray transients, a subclass of x-ray binaries that exhibit violent outbursts. None of the 50 galactic BHs known show eclipses, which is surprising for a random distribution of inclinations. Swift J1357.2-093313 is a very faint x-ray transient detected in 2011. On the basis of spectroscopic evidence, we show that it contains a BH in a 2.8-hour orbital period. Further, high-time-resolution optical light curves display profound dips without x-ray counterparts. The observed properties are best explained by the presence of an obscuring toroidal structure moving outward in the inner disk, seen at very high inclination. This observational feature should play a key role in models of inner accretion flows and jet collimation mechanisms in stellar-mass BHs.

Central obscuration effects on optical synthetic aperture imaging

NASA Astrophysics Data System (ADS)

Wang, Xue-wen; Luo, Xiao; Zheng, Li-gong; Zhang, Xue-jun

2014-02-01

Due to the central obscuration problem exists in most optical synthetic aperture systems, it is necessary to analyze its effects on their image performance. Based on the incoherent diffraction limited imaging theory, a Golay-3 type synthetic aperture system was used to study the central obscuration effects on the point spread function (PSF) and the modulation transfer function (MTF). It was found that the central obscuration does not affect the width of the central peak of the PSF and the cutoff spatial frequency of the MTF, but attenuate the first sidelobe of the PSF and the midfrequency of the MTF. The imaging simulation of a Golay-3 type synthetic aperture system with central obscuration proved this conclusion. At last, a Wiener Filter restoration algorithm was used to restore the image of this system, the images were obviously better.

Compton thick active galactic nuclei in Chandra surveys

NASA Astrophysics Data System (ADS)

Brightman, Murray; Nandra, Kirpal; Salvato, Mara; Hsu, Li-Ting; Aird, James; Rangel, Cyprian

2014-09-01

We present the results from an X-ray spectral analysis of active galactic nuclei (AGN) in the ChandraDeep Field-South, All-wavelength Extended Groth-strip International Survey (AEGIS)-Deep X-ray survey (XD) and Chandra-Cosmic Evolution Surveys (COSMOS), focusing on the identification and characterization of the most heavily obscured, Compton thick (CT, NH > 1024 cm-2) sources. Our sample is comprised of 3184 X-ray selected extragalactic sources, which has a high rate of redshift completeness (96.6 per cent), and includes additional spectroscopic redshifts and improved photometric redshifts over previous studies. We use spectral models designed for heavily obscured AGN which self-consistently include all major spectral signatures of heavy absorption. We validate our spectral fitting method through simulations, identify CT sources not selected through this method using X-ray colours and take considerations for the constraints on NH given the low count nature of many of our sources. After these considerations, we identify a total of 100 CT AGN with best-fitting NH > 1024 cm-2 and NH constrained to be above 1023.5 cm-2 at 90 per cent confidence. These sources cover an intrinsic 2-10 keV X-ray luminosity range of 1042-3 × 1045 erg s-1 and a redshift range of z = 0.1-4. This sample will enable characterization of these heavily obscured AGN across cosmic time and to ascertain their cosmological significance. These survey fields are sites of extensive multiwavelength coverage, including near-infrared Cosmic Assembly Near-infrared Deep Extragalactic Legacy Survey (CANDELS) data and far-infrared Herschel data, enabling forthcoming investigations into the host properties of CT AGN. Furthermore, by using the torus models to test different covering factor scenarios, and by investigating the inclusion of the soft scattered emission, we find evidence that the covering factor of the obscuring material decreases with LX for all redshifts, consistent with the receding torus model, and that this factor increases with redshift, consistent with an increase in the obscured fraction towards higher redshifts. The strong relationship between the parameters of obscuration and LX points towards an origin intrinsic to the AGN; however, the increase of the covering factor with redshift may point towards contributions to the obscuration by the host galaxy. We make NH, Γ (with uncertainties), observed X-ray fluxes and intrinsic 2-10 keV luminosities for all sources analysed in this work publicly available in an online catalogue.

Black carbon, particle number concentration and nitrogen oxide emission factors of random in-use vehicles measured with the on-road chasing method

NASA Astrophysics Data System (ADS)

Ježek, I.; Katrašnik, T.; Westerdahl, D.; Močnik, G.

2015-10-01

The chasing method was used in an on-road measurement campaign, and emission factors (EF) of black carbon (BC), particle number (PN) and nitrogen oxides (NOx) were determined for 139 individual vehicles of different types encountered on the roads. The aggregated results provide EFs for BC, NOx and PN for three vehicle categories: goods vehicles, gasoline and diesel passenger cars. This is the first on-road measurement study where BC EFs of numerous individual diesel cars were determined in real-world driving conditions. We found good agreement between EFs of goods vehicles determined in this campaign and the results of previous studies that used either chasing or remote-sensing measurement techniques. The composition of the sampled car fleet determined from the national vehicle registry information is reflective of Eurostat statistical data on the Slovenian and European vehicle fleet. The median BC EF of diesel and gasoline cars that were in use for less than 5 years decreased by 60 and 47 % from those in use for 5-10 years, respectively; the median NOx and PN EFs of goods vehicles that were in use for less than 5 years decreased from those in use for 5-10 years by 52 and 67 %, respectively. Surprisingly, we found an increase of BC EFs in the newer goods vehicle fleet compared to the 5-10-year old one. The influence of engine maximum power of the measured EFs showed an increase in NOx EF from least to more powerful vehicles with diesel engines. Finally, a disproportionate contribution of high emitters to the total emissions of the measured fleet was found; the top 25 % of emitting diesel cars contributed 63, 47 and 61 % of BC, NOx and PN emissions respectively. With the combination of relatively simple on-road measurements and sophisticated post processing, individual vehicle EF can be determined and useful information about the fleet emissions can be obtained by exactly representing vehicles which contribute disproportionally to vehicle fleet emissions; and monitor how the numerous emission reduction approaches are reflected in on-road driving conditions.

Do male breeding displays function to attract mates or defend territories? The explanatory role of mate and site fidelity

USGS Publications Warehouse

Lanctot, Richard B.; Sandercock, B.K.; Kempenaers, Bart

2000-01-01

Many shorebirds show elaborate breeding displays that include aerial flights and ground displays accompanied by song. The mate attraction hypothesis suggests that breeding displays function to attract mates and maintain pair bonds, whereas the territory defense hypothesis suggests breeding displays function in defining and defending nesting and feeding territories. We tested these hypotheses in the Western Sandpiper (Calidris mauri) by contrasting the duration and level of male breeding displays among pairs that differed in their mate and site fidelity. As predicted by the mate attraction hypothesis, males performed the highest number of song sequences during pair formation, and males paired with their mate of a prior year sang less than males paired to new mates. Further, sitefaithful males mated to a new but experienced mate displayed significantly more than remated males or males new to the area. This suggests a male's prior familiarity with an area and his neighbors does not lessen his display rate as was predicted under the territory defense hypothesis. Limited support for the territory defense hypothesis came from observations of males performing breeding displays with neighboring males along nest territory boundaries. This behavior was short-lived, however, as males abandoned nesting areas after pair-formation and used adjacent or disjointed feeding areas during egg-laying and incubation. Male aggression (i.e., aerial and ground chases), as opposed to breeding displays, appeared to be the principal means of maintaining territory boundaries. Indeed, the rate at which males chased other males remained fairly constant and high throughout the breeding season. Male chasing behavior may also serve as a paternity guard to protect against extra-pair copulations. Our study also found that a female's prior breeding experience in an area correlated with a reduced display rate by her mate, particularly if that mate was new to the area. This indicates female characteristics may not only drive nest initiation, as has been shown in other studies, but are important in determining the duration and extent of male display.

Three-Station Three-dimensional Bolus-Chase MR Angiography with Real-time Fluoroscopic Tracking

PubMed Central

Johnson, Casey P.; Weavers, Paul T.; Borisch, Eric A.; Grimm, Roger C.; Hulshizer, Thomas C.; LaPlante, Christine C.; Rossman, Phillip J.; Glockner, James F.; Young, Phillip M.

2014-01-01

Purpose To determine the feasibility of using real-time fluoroscopic tracking for bolus-chase magnetic resonance (MR) angiography of peripheral vasculature to image three stations from the aortoiliac bifurcation to the pedal arteries. Materials and Methods This prospective study was institutional review board approved and HIPAA compliant. Eight healthy volunteers (three men; mean age, 48 years; age range, 30–81 years) and 13 patients suspected of having peripheral arterial disease (five men; mean age, 67 years; age range, 47–81 years) were enrolled and provided informed consent. All subjects were imaged with the fluoroscopic tracking MR angiographic protocol. Ten patients also underwent a clinical computed tomographic (CT) angiographic runoff examination. Two readers scored the MR angiographic studies for vessel signal intensity and sharpness and presence of confounding artifacts and venous contamination at 35 arterial segments. Mean aggregate scores were assessed. The paired MR angiographic and CT angiographic studies also were scored for visualization of disease, reader confidence, and overall diagnostic quality and were compared by using a Wilcoxon signed rank test. Results Real-time fluoroscopic tracking performed well technically in all studies. Vessel segments were scored good to excellent in all but the following categories: For vessel signal intensity and sharpness, the abdominal aorta, iliac arteries, distal plantar arteries, and plantar arch were scored as fair to good; and for presence of confounding artifacts, the abdominal aorta and iliac arteries were scored as fair. The MR angiograms and CT angiograms did not differ significantly in any scoring category (reader 1: P = .50, .39, and .39; reader 2: P = .41, .61, and .33, respectively). CT scores were substantially better in 20% (four of 20) and 25% (five of 20) of the pooled evaluations for the visualization of disease and overall image quality categories, respectively, versus 5% (one of 20) for MR scores in both categories. Conclusion Three-station bolus-chase MR angiography with real-time fluoroscopic tracking provided high-spatial-resolution arteriograms of the peripheral vasculature, enabled precise triggering of table motion, and compared well with CT angiograms. © RSNA, 2014 Online supplemental material is available for this article. PMID:24635676

Determining the relative toxicity and smoke obscuration of combustion products of mine combustibles. Report of Investigations/1990

DOE Office of Scientific and Technical Information (OSTI.GOV)

De Rosa, M.I.; Litton, C.D.

1990-01-01

Combustible materials, when burned, produce toxic gases and smoke, which may vary dramatically from one material to another, with resultant different total toxicity and smoke obscuration levels. The U.S. Bureau of Mines report presents smoke property data acquired for a variety of mine combustibles and shows that there exists a correlation between the smoke properties, the relative toxicity, and the smoke obscuration levels of those combustibles tested. These correlations can be used to devise simple, standard tests for determining the toxic and smoke obscuration hazards of mine materials during fire.

How moths escape bats: predicting outcomes of predator-prey interactions.

PubMed

Corcoran, Aaron J; Conner, William E

2016-09-01

What determines whether fleeing prey escape from attacking predators? To answer this question, biologists have developed mathematical models that incorporate attack geometries, pursuit and escape trajectories, and kinematics of predator and prey. These models have rarely been tested using data from actual predator-prey encounters. To address this problem, we recorded multi-camera infrared videography of bat-insect interactions in a large outdoor enclosure. We documented 235 attacks by four Myotis volans bats on a variety of moths. Bat and moth flight trajectories from 50 high-quality attacks were reconstructed in 3-D. Despite having higher maximum velocity, deceleration and overall turning ability, bats only captured evasive prey in 69 of 184 attacks (37.5%); bats captured nearly all moths not evading attack (50 of 51; 98%). Logistic regression indicated that prey radial acceleration and escape angle were the most important predictors of escape success (44 of 50 attacks correctly classified; 88%). We found partial support for the turning gambit mathematical model; however, it underestimated the escape threshold by 25% of prey velocity and did not account for prey escape angle. Whereas most prey escaping strikes flee away from predators, moths typically escaped chasing bats by turning with high radial acceleration toward 'safety zones' that flank the predator. This strategy may be widespread in prey engaged in chases. Based on these findings, we developed a novel geometrical model of predation. We discuss implications of this model for the co-evolution of predator and prey kinematics and pursuit and escape strategies. © 2016. Published by The Company of Biologists Ltd.

Characterizing the evolution of WISE-selected obscured and unobscured quasars using HOD models.

NASA Astrophysics Data System (ADS)

Myers, Adam D.; DiPompeo, Michael A.; Mitra, Kaustav; Hickox, Ryan C.; Chatterjee, Suchetana; Whalen, Kelly

2018-06-01

Large-area imaging surveys in the infrared are now beginning to unlock the links between the activity of supermassive black holes and the cosmic evolution of dark matter halos during the significant times when black hole growth is enshrouded in dust. With data from the Wide-Field Infrared Survey Explorer (WISE) and complementary optical photometry, we construct samples of nearly half-a-million obscured and unobscured quasars around redshift 1. We study the dark matter halos of these populations using both angular autocorrelation functions and CMB lensing cross-correlations, carefully characterizing the redshift distribution of the obscured quasar sample using cross-correlations. Independent of our measurement technique, we find that obscured quasars occupy dark matter halos a few times more massive than their unobscured counterparts, despite being matched in luminosity at 12 and 22 microns. Modeling the two-point correlation function using a four-parameter Halo Occupation Distribution (HOD) formalism, we determine that purely optically selected quasars reside in dark matter halos that are about half the mass of WISE-selected obscured quasars, and that satellite fractions are somewhat larger for obscured quasars. We investigate scenarios such as merger-driven fueling and Eddington-dependent obscuration to explore what combinations of physical effects can reproduce our observed halo mass measurements. This work was, in part, supported by NASA ADAP award NNX16AN48G.

Correcting the Relative Bias of Light Obscuration and Flow Imaging Particle Counters.

PubMed

Ripple, Dean C; Hu, Zhishang

2016-03-01

Industry and regulatory bodies desire more accurate methods for counting and characterizing particles. Measurements of proteinaceous-particle concentrations by light obscuration and flow imaging can differ by factors of ten or more. We propose methods to correct the diameters reported by light obscuration and flow imaging instruments. For light obscuration, diameters were rescaled based on characterization of the refractive index of typical particles and a light scattering model for the extinction efficiency factor. The light obscuration models are applicable for either homogeneous materials (e.g., silicone oil) or for chemically homogeneous, but spatially non-uniform aggregates (e.g., protein aggregates). For flow imaging, the method relied on calibration of the instrument with silica beads suspended in water-glycerol mixtures. These methods were applied to a silicone-oil droplet suspension and four particle suspensions containing particles produced from heat stressed and agitated human serum albumin, agitated polyclonal immunoglobulin, and abraded ethylene tetrafluoroethylene polymer. All suspensions were measured by two flow imaging and one light obscuration apparatus. Prior to correction, results from the three instruments disagreed by a factor ranging from 3.1 to 48 in particle concentration over the size range from 2 to 20 μm. Bias corrections reduced the disagreement from an average factor of 14 down to an average factor of 1.5. The methods presented show promise in reducing the relative bias between light obscuration and flow imaging.

The heating of dust in starburst galaxies: The contribution of the nonionizing radiation

NASA Technical Reports Server (NTRS)

Calzetti, D.; Bohlin, R. C.; Kinney, Anne L.; Storchi-Bergmann, T.; Heckman, Timothy M.

1995-01-01

The IUE UV and optical spectra and the far-infrared (FIR) IRAS flux densities of a sample of starburst and blue compact galaxies are used to investigate the relationship between dust obscuration and dust emission. The amount of dust obscuration at UV wavelengths correlates with the FIR-to-blue ratio; and an analysis of the correlation indicates that not only the ionizing but also the nonionizing radiation contribute to the FIR emission. The amount of UV and optical energy lost to dust obscuration accounts for most of the cool dust FIUR emission and for about 70% of the warm dust FIR emission. The remaining 30% of the warm dust FIR flux is probably due to dust emission from regions of star formation which are embedded in opaque giant molecular clouds and do not contribute to the integrated UV and optical spectrum. The use of the FIR emission as an indicator of high-mass star formation rate in star-forming galaxies can be problematic, since the contribution to the FIR flux from cool dust emission heated by relatively old stars is nonnegligible.

75 FR 51293 - [Disaster Declaration greek-i12272 and greek-i12273

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-19

... on 08/10/2010, Private Non- Profit organizations that provide essential services of governmental... Counties: Atchison, Brown, Butler, Chase, Clay, Cloud, Comanche, Doniphan, Ellis, Franklin, Greenwood...

GAMA/H-ATLAS: the ultraviolet spectral slope and obscuration in galaxies

NASA Astrophysics Data System (ADS)

Wijesinghe, D. B.; da Cunha, E.; Hopkins, A. M.; Dunne, L.; Sharp, R.; Gunawardhana, M.; Brough, S.; Sadler, E. M.; Driver, S.; Baldry, I.; Bamford, S.; Liske, J.; Loveday, J.; Norberg, P.; Peacock, J.; Popescu, C. C.; Tuffs, R.; Andrae, E.; Auld, R.; Baes, M.; Bland-Hawthorn, J.; Buttiglione, S.; Cava, A.; Cameron, E.; Conselice, C. J.; Cooray, A.; Croom, S.; Dariush, A.; Dezotti, G.; Dye, S.; Eales, S.; Frenk, C.; Fritz, J.; Hill, D.; Hopwood, R.; Ibar, E.; Ivison, R.; Jarvis, M.; Jones, D. H.; van Kampen, E.; Kelvin, L.; Kuijken, K.; Maddox, S. J.; Madore, B.; Michałowski, M. J.; Nichol, B.; Parkinson, H.; Pascale, E.; Pimbblet, K. A.; Pohlen, M.; Prescott, M.; Rhodighiero, G.; Robotham, A. S. G.; Rigby, E. E.; Seibert, M.; Sergeant, S.; Smith, D. J. B.; Temi, P.; Sutherland, W.; Taylor, E.; Thomas, D.; van der Werf, P.

2011-08-01

We use multiwavelength data from the Galaxy And Mass Assembly (GAMA) and Herschel-ATLAS (H-ATLAS) surveys to compare the relationship between various dust obscuration measures in galaxies. We explore the connections between the ultraviolet (UV) spectral slope, β, the Balmer decrement and the far-infrared (FIR) to 150 nm far-ultraviolet (FUV) luminosity ratio. We explore trends with galaxy mass, star formation rate (SFR) and redshift in order to identify possible systematics in these various measures. We reiterate the finding of other authors that there is a large scatter between the Balmer decrement and the β parameter, and that β may be poorly constrained when derived from only two broad passbands in the UV. We also emphasize that FUV-derived SFRs, corrected for dust obscuration using β, will be overestimated unless a modified relation between β and the attenuation factor is used. Even in the optimum case, the resulting SFRs have a significant scatter, well over an order of magnitude. While there is a stronger correlation between the IR-to-FUV luminosity ratio and β parameter than with the Balmer decrement, neither of these correlations are particularly tight, and dust corrections based on β for high-redshift galaxy SFRs must be treated with caution. We conclude with a description of the extent to which the different obscuration measures are consistent with each other as well as the effects of including other galactic properties on these correlations.

The evolution of obscured AGN

NASA Astrophysics Data System (ADS)

Brightman, Murray

2012-09-01

We present results on the evolution of Compton thick AGN with redshift, and the nature of this obscuration, important for understanding the accretion history of the universe and for AGN unification schemes. We use lessons learned from spectral complexity of local AGN (Brightman & Nandra 2012) and up to date spectral models of heavily absorbed AGN, which take into account Compton scattering, self consistent Fe Ka modeling and the geometry of the circumnuclear material (Brightman & Nandra 2011), to optimise our identification of Compton thick AGN and understanding of the obscuring material. Results from the Chandra Deep Field South are presented (Brightman & Ueda, 2012), which show an increasing fraction of CTAGN with redshift and that most heavily obscured AGN are geometrically deeply buried in material, as well as new results from and extension of this study to AEGIS-XD and Chandra-COSMOS survey, which aim to fully characterise the dependence of heavy AGN obscuration on redshift and luminosity.

The Compton-thick Growth of Supermassive Black Holes constrained

NASA Astrophysics Data System (ADS)

Buchner, Johannes; Georgakakis, Antonis; Nandra, Kirpal; Brightman, Murray; Menzel, Marie-Luise; Liu, Zhu; Hsu, Li-Ting; Salvato, Mara; Rangel, Cyprian; Aird, James

2017-08-01

A heavily obscured growth phase of supermassive black holes (SMBH) is thought to be important in the co-evolution with galaxies. X-rays provide a clean and efficient selection of unobscured and obscured AGN. Recent work with deeper observations and improved analysis methodology allowed us to extend constraints to Compton-thick number densities. We present the first luminosity function of Compton-thick AGN at z=0.5-4 and constrain the overall mass density locked into black holes over cosmic time, a fundamental constraint for cosmological simulations. Recent studies including ours find that the obscuration is redshift and luminosity-dependent in a complex way, which rules out entire sets of obscurer models. A new paradigm, the radiation-lifted torus model, is proposed, in which the obscurer is Eddington-rate dependent and accretion creates and displaces torus clouds. We place observational limits on the behaviour of this mechanism.

The Compton-thick Growth of Supermassive Black Holes constrained

NASA Astrophysics Data System (ADS)

Buchner, J.; Georgakakis, A.; Nandra, K.

2017-10-01

A heavily obscured growth phase of supermassive black holes (SMBH) is thought to be important in the co-evolution with galaxies. X-rays provide a clean and efficient selection of unobscured and obscured AGN. Recent work with deeper observations and improved analysis methodology allowed us to extend constraints to Compton-thick number densities. We present the first luminosity function of Compton-thick AGN at z=0.5-4 and constrain the overall mass density locked into black holes over cosmic time, a fundamental constraint for cosmological simulations. Recent studies including ours find that the obscuration is redshift and luminosity-dependent in a complex way, which rules out entire sets of obscurer models. A new paradigm, the radiation-lifted torus model, is proposed, in which the obscurer is Eddington-rate dependent and accretion creates and displaces torus clouds. We place observational limits on the behaviour of this mechanism.

The Swift Burst and Transient Telescope (BAT)

NASA Technical Reports Server (NTRS)

Mushotzky, Richard

2008-01-01

The Swift Burst and Transient telescope (BAT) has surveyed the entire sky for the last 3.5 years obtaining the first sensitive all sky survey of the 14-195 kev sky. At high galactic latitudes the vast majority of the detected sources are AGN. Since hard x-rays penetrate all but Compton thick obscuring material (Column densities of 1.6324 atms/sq cm) this survey is unbiased with respect to obscuration, host galaxy type, optical , radio or IR properties. We will present results on the broad band x-ray properties, the nature of the host galaxies, the luminosity function and will discuss a few of the optical, IR and x-ray results in detail.

2. Overview of site, looking southeast Naval Air Station ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

2. Overview of site, looking southeast - Naval Air Station Chase Field, Building 1001, Independence Street, .45 mile south of intersection of Texas State Highway & Independence Street, Beeville, Bee County, TX

7. Overview of site, looking southwest Naval Air Station ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

7. Overview of site, looking southwest - Naval Air Station Chase Field, Building 1001, Independence Street, .45 mile south of intersection of Texas State Highway & Independence Street, Beeville, Bee County, TX

1. Overview of site, looking northwest Naval Air Station ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

1. Overview of site, looking northwest - Naval Air Station Chase Field, Building 1001, Independence Street, .45 mile south of intersection of Texas State Highway & Independence Street, Beeville, Bee County, TX

8. Overview of site, looking northeast Naval Air Station ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

8. Overview of site, looking northeast - Naval Air Station Chase Field, Building 1001, Independence Street, .45 mile south of intersection of Texas State Highway & Independence Street, Beeville, Bee County, TX

ARC-2007-ACD07-0189-018

NASA Image and Video Library

2007-10-02

International Space Station (ISS) National Laboratory Workshop L-R Lynn Harper, Ames and Baruch Blumberg, Nobel Laureate, Fox Chase Cancer Center during talk on Science on the international Space Station, Past and Future.

Superresolution and pulse-chase imaging reveal the role of vesicle transport in polar growth of fungal cells

PubMed Central

Zhou, Lu; Evangelinos, Minoas; Wernet, Valentin; Eckert, Antonia F.; Ishitsuka, Yuji; Fischer, Reinhard; Nienhaus, G. Ulrich; Takeshita, Norio

2018-01-01

Polarized growth of filamentous fungi requires continuous transport of biomolecules to the hyphal tip. To this end, construction materials are packaged in vesicles and transported by motor proteins along microtubules and actin filaments. We have studied these processes with quantitative superresolution localization microscopy of live Aspergillus nidulans cells expressing the photoconvertible protein mEosFPthermo fused to the chitin synthase ChsB. ChsB is mainly located at the Spitzenkörper near the hyphal tip and produces chitin, a key component of the cell wall. We have visualized the pulsatory dynamics of the Spitzenkörper, reflecting vesicle accumulation before exocytosis and their subsequent fusion with the apical plasma membrane. Furthermore, high-speed pulse-chase imaging after photoconversion of mEosFPthermo in a tightly focused spot revealed that ChsB is transported with two different speeds from the cell body to the hyphal tip and vice versa. Comparative analysis using motor protein deletion mutants allowed us to assign the fast movements (7 to 10 μm s−1) to transport of secretory vesicles by kinesin-1, and the slower ones (2 to 7 μm s−1) to transport by kinesin-3 on early endosomes. Our results show how motor proteins ensure the supply of vesicles to the hyphal tip, where temporally regulated exocytosis results in stepwise tip extension. PMID:29387789

Hubble Chases a Small Stellar Galaxy in the Hunting Dog

NASA Image and Video Library

2017-12-08

On a clear evening in April of 1789, the renowned astronomer William Herschel continued his unrelenting survey of the night sky, hunting for new cosmic objects — and found cause to celebrate! He spotted this bright spiral galaxy, named NGC 4707, lurking in the constellation of Canes Venatici or The Hunting Dog. NGC 4707 lies roughly 22 million light-years from Earth. Over two centuries later, the NASA/ESA Hubble Space Telescope is able to "chase down" and view the same galaxy in far greater detail than Herschel could, allowing us to appreciate the intricacies and characteristics of NGC 4707 as never before. This striking image comprises observations from Hubble’s Advanced Camera for Surveys (ACS), one of a handful of high-resolution instruments currently aboard the space telescope. Herschel himself reportedly described NGC 4707 as a “small, stellar” galaxy; while it is classified as a spiral (type Sm), its overall shape, center, and spiral arms are very loose and undefined, and its central bulge is either very small or non-existent. It instead appears as a rough sprinkling of stars and bright flashes of blue on a dark canvas. The blue smudges seen across the frame highlight regions of recent or ongoing star formation, with newborn stars glowing in bright, intense shades of cyan and turquoise. Image credit: ESA/Hubble & NASA

"Sniffer"—a novel tool for chasing vehicles and measuring traffic pollutants

NASA Astrophysics Data System (ADS)

Pirjola, L.; Parviainen, H.; Hussein, T.; Valli, A.; Hämeri, K.; Aaalto, P.; Virtanen, A.; Keskinen, J.; Pakkanen, T. A.; Mäkelä, T.; Hillamo, R. E.

To measure traffic pollutants with high temporal and spatial resolution under real conditions a mobile laboratory was designed and built in Helsinki Polytechnic in close co-operation with the University of Helsinki. The equipment of the van provides gas phase measurements of CO and NO x, number size distribution measurements of fine and ultrafine particles by an electrical low pressure impactor, an ultrafine condensation particle counter and a scanning mobility particle sizer. Two inlet systems, one above the windshield and the other above the bumper, enable chasing of different type of vehicles. Also, meteorological and geographical parameters are recorded. This paper introduces the construction and technical details of the van, and presents data from the measurements performed during an LIPIKA campaign on the highway in Helsinki. Approximately 90% of the total particle number concentration was due to particles smaller than 50 nm on the highway in Helsinki. The peak concentrations exceeded often 200,000 particles cm -3 and reached sometimes a value of 10 6 cm -3. Typical size distribution of fine particles possessed bimodal structure with the modal mean diameters of 15-20 nm and ˜150 nm. Atmospheric dispersion of traffic pollutions were measured by moving away from the highway along the wind direction. At a distance of 120-140 m from the source the concentrations were diluted to one-tenth from the values at 9 m from the source.

Quantitative Description of Obscuration Factors for Electro-Optical and Millimeter Wave Systems

DTIC Science & Technology

1986-07-25

length 1. through an obscurant of Standard meteorological ineasurables include air knIown concentration. F-or nonuniform obscurants dlis- temaperature...Wavelengths -ya(X) are ’l 1111m precilpitatioi v’olun exft tct it ozi cot’fficiewi Visible (0..l-O.7pmii) lair . 3-2.2.1 for snoxv dp(U)(epeicids onl lain

Evolution of cosmic star formation in the SCUBA-2 Cosmology Legacy Survey

NASA Astrophysics Data System (ADS)

Bourne, N.; Dunlop, J. S.; Merlin, E.; Parsa, S.; Schreiber, C.; Castellano, M.; Conselice, C. J.; Coppin, K. E. K.; Farrah, D.; Fontana, A.; Geach, J. E.; Halpern, M.; Knudsen, K. K.; Michałowski, M. J.; Mortlock, A.; Santini, P.; Scott, D.; Shu, X. W.; Simpson, C.; Simpson, J. M.; Smith, D. J. B.; van der Werf, P. P.

2017-05-01

We present a new exploration of the cosmic star formation history and dust obscuration in massive galaxies at redshifts 0.5 < z < 6. We utilize the deepest 450- and 850-μm imaging from SCUBA-2 CLS, covering 230 arcmin2 in the AEGIS, COSMOS and UDS fields, together with 100-250 μm imaging from Herschel. We demonstrate the capability of the t-phot deconfusion code to reach below the confusion limit, using multiwavelength prior catalogues from CANDELS/3D-HST. By combining IR and UV data, we measure the relationship between total star formation rate (SFR) and stellar mass up to z ˜ 5, indicating that UV-derived dust corrections underestimate the SFR in massive galaxies. We investigate the relationship between obscuration and the UV slope (the IRX-β relation) in our sample, which is similar to that of low-redshift starburst galaxies, although it deviates at high stellar masses. Our data provide new measurements of the total SFR density (SFRD) in M_{\\ast }>10^{10} M_{⊙} galaxies at 0.5 < z < 6. This is dominated by obscured star formation by a factor of >10. One third of this is accounted for by 450-μm-detected sources, while one-fifth is attributed to UV-luminous sources (brighter than L_UV^\\ast), although even these are largely obscured. By extrapolating our results to include all stellar masses, we estimate a total SFRD that is in good agreement with previous results from IR and UV data at z ≲ 3, and from UV-only data at z ˜ 5. The cosmic star formation history undergoes a transition at z ˜ 3-4, as predominantly unobscured growth in the early Universe is overtaken by obscured star formation, driven by the build-up of the most massive galaxies during the peak of cosmic assembly.

INFRARED SPECTROSCOPY OF SYMBIOTIC STARS. IX. D-TYPE SYMBIOTIC NOVAE

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hinkle, Kenneth H.; Joyce, Richard R.; Fekel, Francis C.

2013-06-10

Time-series spectra of the near-infrared 1.6 {mu}m region have been obtained for five of the six known D-type symbiotic novae. The spectra map the pulsation kinematics of the Mira component in the Mira-white dwarf binary system and provide the center-of-mass velocity for the Mira. No orbital motion is detected in agreement with previous estimates of orbital periods {approx}>100 yr and semimajor axes {approx}50 AU. The 1-5 {mu}m spectra of the Miras show line weakening during dust obscuration events. This results from scattering and continuum emission by 1000 K dust. In the heavily obscured HM Sge system the 4.6 {mu}m COmore » spectrum formed in 1000 K gas is seen in emission against an optically thick dust continuum. Spectral features that are typically produced in either the cool molecular region or the expanding circumstellar region of late-type stars cannot be detected in the D-symbiotic novae. This is in accord with the colliding wind model for interaction between the white dwarf and Mira. Arguments are presented that the 1000 K gas and dust are not Mira circumstellar material but are in the wind interaction region of the colliding winds. CO is the first molecule detected in this region. We suggest that dust condensing in the intershock region is the origin of the dust obscuration. This model explains variations in the obscuration. Toward the highly obscured Mira in HM Sge the dust zone is estimated to be {approx}0.1 AU thick. The intershock wind interaction zone appears thinnest in the most active systems. Drawing on multiple arguments masses are estimated for the system components. The Miras in most D-symbiotic novae have descended from intermediate mass progenitors. The large amount of mass lost from the Mira combined with the massive white dwarf companion suggests that these systems are supernova candidates. However, timescales and the number of objects make these rare events.« less

Healthy Weight: You Can Do It, Too

MedlinePlus

... diet") and gets regular exercise. Photos: Russell Morgan Russell Morgan changed the way he eats and exercises, ... a recent eight-month period, public health expert Russell Morgan, 66, of Chevy Chase, Md., dropped 60 ...

Significance chasing in research practice: causes, consequences and possible solutions.

PubMed

Ware, Jennifer J; Munafò, Marcus R

2015-01-01

The low reproducibility of findings within the scientific literature is a growing concern. This may be due to many findings being false positives which, in turn, can misdirect research effort and waste money. We review factors that may contribute to poor study reproducibility and an excess of 'significant' findings within the published literature. Specifically, we consider the influence of current incentive structures and the impact of these on research practices. The prevalence of false positives within the literature may be attributable to a number of questionable research practices, ranging from the relatively innocent and minor (e.g. unplanned post-hoc tests) to the calculated and serious (e.g. fabrication of data). These practices may be driven by current incentive structures (e.g. pressure to publish), alongside the preferential emphasis placed by journals on novelty over veracity. There are a number of potential solutions to poor reproducibility, such as new publishing formats that emphasize the research question and study design, rather than the results obtained. This has the potential to minimize significance chasing and non-publication of null findings. Significance chasing, questionable research practices and poor study reproducibility are the unfortunate consequence of a 'publish or perish' culture and a preference among journals for novel findings. It is likely that top-down change implemented by those with the ability to modify current incentive structure (e.g. funders and journals) will be required to address problems of poor reproducibility. © 2014 Society for the Study of Addiction.

Significance chasing in research practice: Causes, consequences, and possible solutions

PubMed Central

Ware, Jennifer J.; Munafò, Marcus R.

2016-01-01

Background and Aims The low reproducibility of findings within the scientific literature is a growing concern. This may be due to many findings being false positives, which in turn can misdirect research effort and waste money. Methods We review factors that may contribute to poor study reproducibility and an excess of ‘significant’ findings within the published literature. Specifically, we consider the influence of current incentive structures, and the impact of these on research practices. Results The prevalence of false positives within the literature may be attributable to a number of questionable research practices, ranging from the relatively innocent and minor (e.g., unplanned post hoc tests), to the calculated and serious (e.g., fabrication of data). These practices may be driven by current incentive structures (e.g. pressure to publish), alongside the preferential emphasis placed by journals on novelty over veracity. There are a number of potential solutions to poor reproducibility, such as new publishing formats that emphasise the research question and study design, rather than the results obtained. This has the potential to minimise significance chasing and non-publication of null findings. Conclusions Significance chasing, questionable research practices, and poor study reproducibility are the unfortunate consequence of a “publish or perish” culture and a preference among journals for novel findings. It is likely that top-down change implemented by those with the ability to modify current incentive structure (e.g., funders and journals) will be required to address problems of poor reproducibility. PMID:25040652

Characterization of the Photon Counting CHASE Jr., Chip Built in a 40-nm CMOS Process With a Charge Sharing Correction Algorithm Using a Collimated X-Ray Beam

DOE Office of Scientific and Technical Information (OSTI.GOV)

Krzyżanowska, A.; Deptuch, G. W.; Maj, P.

This paper presents the detailed characterization of a single photon counting chip, named CHASE Jr., built in a CMOS 40-nm process, operating with synchrotron radiation. The chip utilizes an on-chip implementation of the C8P1 algorithm. The algorithm eliminates the charge sharing related uncertainties, namely, the dependence of the number of registered photons on the discriminator’s threshold, set for monochromatic irradiation, and errors in the assignment of an event to a certain pixel. The article presents a short description of the algorithm as well as the architecture of the CHASE Jr., chip. The analog and digital functionalities, allowing for proper operationmore » of the C8P1 algorithm are described, namely, an offset correction for two discriminators independently, two-stage gain correction, and different operation modes of the digital blocks. The results of tests of the C8P1 operation are presented for the chip bump bonded to a silicon sensor and exposed to the 3.5- μm -wide pencil beam of 8-keV photons of synchrotron radiation. It was studied how sensitive the algorithm performance is to the chip settings, as well as the uniformity of parameters of the analog front-end blocks. Presented results prove that the C8P1 algorithm enables counting all photons hitting the detector in between readout channels and retrieving the actual photon energy.« less

MAMBO observations at 240GHz of optically obscured Spitzer sources: source clumps and radio activity at high redshift

NASA Astrophysics Data System (ADS)

Andreani, P.; Magliocchetti, M.; de Zotti, G.

2010-01-01

Optically very faint (R > 25.5) sources detected by the Spitzer Space Telescope at 24μm represent a very interesting population at redshift z ~ (1.5-3). They exhibit strong clustering properties, implying that they are hosted by very massive haloes, and their mid-infrared emission could be powered by either dust-enshrouded star formation and/or by an obscured active galactic nucleus (AGN). We report observations carried out with the Max Planck Millimetre Bolometer (MAMBO) array at the IRAM 30-m antenna on Pico Veleta of a candidate protocluster with five optically obscured sources selected from the 24-μm Spitzer sample of the First-Look Survey. Interestingly, these sources appear to lie on a high-density filament aligned with the two radio jets of an AGN. Four out of five of the observed sources were detected. We combine these measurements with optical, infrared and radio observations to probe the nature of the candidate protocluster members. Our preliminary conclusions can be summarized as follows: the spectral energy distributions (SEDs) of all sources include both AGN and starburst contributions; the AGN contribution to the bolometric luminosities ranges between 14 and 26 per cent of the total. Such a contribution is enough for the AGN to dominate the emission at 5.8, 8 and 24μm, while the stellar component, inferred from SED fitting, prevails at 1.25mm and at λ < 4.5μm. The present analysis suggests a coherent interplay at high z between extended radio activity and the development of filamentary large-scale structures.

Infrared astronomy research and high altitude observations

NASA Technical Reports Server (NTRS)

Jones, B.; Stein, W. A.; Willner, S. P.; Soifer, B. T.

1984-01-01

Highlights are presented of studies of the emission mechanisms in the 4 to 8 micron region of the spectrum using a circular variable filter wheel spectrometer with a PbSnTe photovoltaic detector. Investigations covered include the spectroscopy of planets, stellar atmospheres, highly obscured objects in molecular clouds, planetary nebulae, H2 regions, and extragalactic objects.

The highly obscured nucleus of 3C 219

NASA Technical Reports Server (NTRS)

Fabbiano, G.; Willner, S. P.; Carleton, N. P; Elvis, M.

1986-01-01

The detection of a strong, and possibly broad, Paschen-alpha line from the narrow-line radio galaxy 3C 219 is reported. The detected flux is larger than predicted from the H-alpha line and the case B recombination. This implies the presence of a highly reddened line-emitting region in the nucleus.

DefenseLink Special: Doolittle Raid, April 18, 1942

Science.gov Websites

enhanced viewing {Flash 8} Macromedia Flash Player 8 required Download free Macromedia Flash Player Download free Internet Explorer DOOLITTLE RAIDERS – Retired Lt. Col. Chase Nelson, a Doolittle Raider

9. Interior of Building 1040 (gym), looking west Naval ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

9. Interior of Building 1040 (gym), looking west - Naval Air Station Chase Field, Building 1040, Enterprise Street, .37 mile South-Southeast of intersection of Texas State Highway 202 & Independence Street, Beeville, Bee County, TX

10. Interior of Building 1040 (chapel), looking north Naval ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

10. Interior of Building 1040 (chapel), looking north - Naval Air Station Chase Field, Building 1040, Enterprise Street, .37 mile South-Southeast of intersection of Texas State Highway 202 & Independence Street, Beeville, Bee County, TX

8. Overview of Building 1009, looking south Naval Air ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

8. Overview of Building 1009, looking south - Naval Air Station Chase Field, Building 1009, Essex Street, .68 mile South-southeast of intersection of Texas State Highway 202 & Independence Street, Beeville, Bee County, TX

Below the Surface: Solving the Hidden Graduation Rate Crisis. Updated

ERIC Educational Resources Information Center

Cardichon, Jessica; Lovell, Phillip

2015-01-01

The U.S. national high school graduation rate recently reached a record high with 81 percent of the Class of 2013 graduating within four years. While this accomplishment is laudable, it should not obscure the fact that more than 1,200 high schools, serving more than 1.1 million students, still fail to graduate one-third or more of their students…

Protein C deficiency related obscure gastrointestinal bleeding treated by enteroscopy and anticoagulant therapy.

PubMed

Hsu, Wei-Fan; Tsang, Yuk-Ming; Teng, Chung-Jen; Chung, Chen-Shuan

2015-01-21

Obscure gastrointestinal bleeding is an uncommonly encountered and difficult-to-treat clinical problem in gastroenterology, but advancements in endoscopic and radiologic imaging modalities allow for greater accuracy in diagnosing obscure gastrointestinal bleeding. Ectopic varices account for less than 5% of all variceal bleeding cases, and jejunal variceal bleeding due to extrahepatic portal hypertension is rare. We present a 47-year-old man suffering from obscure gastrointestinal bleeding. Computed tomography of the abdomen revealed multiple vascular tufts around the proximal jejunum but no evidence of cirrhosis, and a visible hypodense filling defect suggestive of thrombus was visible in the superior mesenteric vein. Enteroscopy revealed several serpiginous varices in the proximal jejunum. Serologic data disclosed protein C deficiency (33.6%). The patient was successfully treated by therapeutic balloon-assisted enteroscopy and long-term anticoagulant therapy, which is normally contraindicated in patients with gastrointestinal bleeding. Diagnostic modalities for obscure gastrointestinal bleeding, such as capsule endoscopy, computed tomography enterography, magnetic resonance enterography, and enteroscopy, were also reviewed in this article.

Laboratory Evaluation of Light Obscuration Particle Counters used to Establish use Limits for Aviation Fuel

DTIC Science & Technology

2015-12-01

evaluation The major drawback to light obscuration particle counting is that the technology is unable to differentiate between solid particulate ...light obscuration particle counter technologies evaluated were able to properly measure solid particulate contamination and provide an indication of...undissolved water, Aqua-Glo, Particulate , Gravimetric 16. SECURITY CLASSIFICATION OF: 17. LIMITATION OF ABSTRACT none 18. NUMBER OF PAGES 55 19a. NAME OF

A novel balloon colonoscope detects significantly more simulated polyps than a standard colonoscope in a colon model.

PubMed

Hasan, Nazia; Gross, Seth A; Gralnek, Ian M; Pochapin, Mark; Kiesslich, Ralf; Halpern, Zamir

2014-12-01

Although standard colonoscopy is considered the optimal test to detect adenomas, it can have a significant adenoma miss rate. A major contributing factor to high miss rates is the inability to visualize adenomas behind haustral folds and at anatomic flexures. To compare the diagnostic yield of balloon-assisted colonoscopy versus standard colonoscopy in the detection of simulated polyps in a colon model. Prospective, cohort study. International gastroenterology meeting. A colon model composed of elastic material, which mimics the flexible structure of haustral folds, allowing for dynamic responses to balloon inflation, with embedded simulated colon polyps (n = 12 silicone "polyps"). Fifty gastroenterologists were recruited to identify simulated colon polyps in a colon model, first using standard colonoscopy immediately followed by balloon-assisted colonoscopy. Detection of simulated polyps. The median polyp detection rate for all simulated polyps was significantly higher with balloon-assisted as compared with standard colonoscopy (91.7% vs 45.8%, respectively; P < .0001). The significantly higher simulated polyp detection rate with balloon-assisted versus standard colonoscopy was notable both for non-obscured polyps (100.0% vs 75.0%; P < .0001) and obscured polyps (88.0% vs 25.0%; P < .0001). Non-randomized design, use of a colon model, and simulated colon polyps. As compared with standard colonoscopy, balloon-assisted colonoscopy detected significantly more obscured and non-obscured simulated polyps in a colon model. Clinical studies in human participants are being pursued to further evaluate this new colonoscopic technology. Copyright © 2014 American Society for Gastrointestinal Endoscopy. Published by Elsevier Inc. All rights reserved.

Heavily Obscured AGN: An Ideal Laboratory To Study The Early Co-Evolution of Galaxies And Black Holes

NASA Astrophysics Data System (ADS)

Circosta, Chiara; Vignali, C.; Gilli, R.; Feltre, A.; Vito, F.

2016-10-01

Obscured AGN are a crucial ingredient to understand the full growth history of super massive black holes and the coevolution with their host galaxies, since they constitute the bulk of the BH accretion. In the distant Universe, many of them are hosted by submillimeter galaxies (SMGs), characterized by a high production of stars and a very fast consumption of gas. Therefore, the analysis of this class of objects is fundamental to investigate the role of the ISM in the early coevolution of galaxies and black holesWe collected a sample of six obscured X-ray selected AGN at z>2.5 in the CDF-S, detected in the far-IR/submm bands. We performed a multiwavelength analysis in order to characterize their physical properties, as well as those of their host galaxies (e.g. column density, accretion luminosity, stellar mass, SFR, dust and gas mass). I will present the results of the X-ray spectral analysis of these sources based on the 7Ms Chandra data - the deepest X-ray observation ever carried out on any field - along with their broad-band spectral energy distributions (SEDs), built up using the public UV to far-IR photometry from the CANDELS and Herschel catalogs. By comparing the column density associated with the ISM (estimated measuring the size of the system) with that obtained from the X-ray data, it is possible to understand whether the ISM in the host galaxy may be able to produce a substantial part of the observed nuclear obscuration.

Disentangling Quasar Nomenclature

NASA Astrophysics Data System (ADS)

Ross, Nicholas; Goulding, Andrew D.

2015-01-01

The terms Type 1, Type 2, Obscured, Unobscured, Compton-thin and Compton-thick are cemented naming conventions for describing AGN and QSOs. However, all too often, they are used interchangeably to describe seemingly similar/different entities, leading to confusion towards the physical mechanisms that give rise to them. Furthermore, as is often the case in scientific discovery, initial designations and acronyms become obsolete. In this poster, using data and new results from the SDSS, SDSS-III BOSS, Bootes, DEEP2 and WISE surveys, we present a comprehensive QSO Glossary giving clear definitions of numerous AGN terms and the physical interpretation behind them. We further elucidate to the physical nature of hot dust obscured galaxy population (``hot DOGs'') and the long-sought after high-z Type 2 QSO population.

The Swift BAT Hard X-ray Survey - A New Window on the Local AGN Universe

NASA Technical Reports Server (NTRS)

Mushotzky, Richard

2009-01-01

The Swift Burst and Transient telescope (BAT) has surveyed the entire sky for the last 3.5 years obtaining the first sensitive all sky survey of the 14-195 keV sky. At high galactic latitudes the vast majority of the detected sources are AGN. Since hard x-rays penetrate all but Compton thick obscuring material (Column densities of 1.6E24 atms/cm2) this survey is unbiased with respect to obscuration, host galaxy type, optical , radio or IR properties. We will present results on the broad band x-ray properties, the nature of the host galaxies, the luminosity function and will discuss a few of the optical, IR and x-ray results in detail.

X-ray obscured AGN in the GOODS-N

NASA Astrophysics Data System (ADS)

Georgantopoulos, I.; Akylas, A.; Rovilos, E.; Xilouris, M.

2010-07-01

We explore the X-ray properties of the Dust Obscured Galaxies (DOGs) i.e. sources with f24μ/fR>1000. This population has been proposed to contain a significan fraction of Compton-thick sources at high redshift. In particular we study the X-ray spectra of the 14 DOGS detected in the CDFN 2Ms exposure. Their stacked spectrum is fla with Γ = 1+/-0.1 very similar to the stacked spectrum of the undetected DOGs (Γ = 0.8+/-0.2). However, many of our X-ray detected DOGs present only moderate absorption with column densities 1022

Dust Properties of Local Dust-obscured Galaxies with the Submillimeter Array

NASA Astrophysics Data System (ADS)

Hwang, Ho Seong; Andrews, Sean M.; Geller, Margaret J.

2013-11-01

We report Submillimeter Array observations of the 880 μm dust continuum emission for four dust-obscured galaxies (DOGs) in the local universe. Two DOGs are clearly detected with S ν(880 μm) =10-13 mJy and S/N > 5, but the other two are not detected with 3σ upper limits of S ν(880 μm) =5-9 mJy. Including an additional two local DOGs with submillimeter data from the literature, we determine the dust masses and temperatures for six local DOGs. The infrared luminosities and dust masses for these DOGs are in the ranges of 1.2-4.9 × 1011(L ⊙) and 4-14 × 107(M ⊙), respectively. The dust temperatures derived from a two-component modified blackbody function are 23-26 K and 60-124 K for the cold and warm dust components, respectively. Comparison of local DOGs with other infrared luminous galaxies with submillimeter detections shows that the dust temperatures and masses do not differ significantly among these objects. Thus, as argued previously, local DOGs are not a distinctive population among dusty galaxies, but simply represent the high-end tail of the dust obscuration distribution.

The Compton-thick AGN fraction from the deepest X-ray spectroscopy in the CDF-S

NASA Astrophysics Data System (ADS)

Corral, A.; Georgantopoulos, I.; Akylas, A.; Ranalli, P.

2017-10-01

Highly obscured AGN, especially Compton-thick (CT) AGN, likely play a key role in the galaxy-AGN co-evolution scenario. They would comprise the early stages of AGN activity, preceding the AGN-feedback/star-formation quenching phase, during which most of both the SMBH and galaxy growth take place. However, the actual CT fraction among the AGN population is still largely unconstrained. The most reliable way of confirming the obscured nature of an AGN by X-ray spectroscopy, but very deep observations are needed to extend local analyses to larger distances. We will present the X-ray spectral analysis of the deepest X-ray data obtained to date, the almost 7Ms observation of the Chandra Deep Field South. The unprecedented depth of this survey allow us to carry out reliable spectral analyses down to a flux limit of 10^{-16} erg cm^{-2} s^{-1} in the hard 2-8 keV band. Besides the new deeper X-ray data, our approach also includes the implementation of Bayesian inference in the determination of the CT fraction. Our results favor X-ray background synthesis models which postulate a moderate fraction (25%) of CT objects among the obscured AGN population.

Uncovering Heavily Obscured AGN with WISE and NuSTAR

NASA Astrophysics Data System (ADS)

Hickox, Ryan C.; Carroll, Christopher M.; Yan, Wei; DiPompeo, Michael A.; Hainline, Kevin N.; NuSTAR Obscured AGN Team

2018-01-01

Supermassive black holes gain their mass through accretion as active galactic nuclei (AGN), but it is now clear that a large fraction of this growth is "hidden" behind large columns of gas and dust. Of particular interest are Compton-thick (CT) AGN, with columns NH > 1024 cm-2, that have been difficult to identify using optical or soft X-ray surveys. We will present two studies of heavily obscured AGN that aim to uncover more of the full population of "hidden" growing black holes: (1) Analysis of the spectral energy distributions of millions of galaxies with photometry from WISE (mid-IR), UKIDSS (near-IR), and SDSS (optical), that uncovers large populations of weak or heavily buried AGN, and (2) NuSTAR observations of a sample of candidate highly obscured AGN, selected from WISE and SDSS photometry,and confirmed using SALT and Keck spectroscopy. The NuSTAR data reveal the existence of powerful CT quasars with extremely large columns NH > 1025 cm-2, which may represent a significant fraction of previously hidden black hole growth. This work is supported by NASA grant numbers NNX16AN48G and NNX15AP24G, and the NSF through grant numbers 1515364 and 1554584.

BAT AGN Spectroscopic Survey. V. X-Ray Properties of the Swift/BAT 70-month AGN Catalog

NASA Astrophysics Data System (ADS)

Ricci, C.; Trakhtenbrot, B.; Koss, M. J.; Ueda, Y.; Del Vecchio, I.; Treister, E.; Schawinski, K.; Paltani, S.; Oh, K.; Lamperti, I.; Berney, S.; Gandhi, P.; Ichikawa, K.; Bauer, F. E.; Ho, L. C.; Asmus, D.; Beckmann, V.; Soldi, S.; Baloković, M.; Gehrels, N.; Markwardt, C. B.

2017-12-01

Hard X-ray (≥10 keV) observations of active galactic nuclei (AGNs) can shed light on some of the most obscured episodes of accretion onto supermassive black holes. The 70-month Swift/BAT all-sky survey, which probes the 14-195 keV energy range, has currently detected 838 AGNs. We report here on the broadband X-ray (0.3-150 keV) characteristics of these AGNs, obtained by combining XMM-Newton, Swift/XRT, ASCA, Chandra, and Suzaku observations in the soft X-ray band (≤slant 10 keV) with 70-month averaged Swift/BAT data. The nonblazar AGNs of our sample are almost equally divided into unobscured ({N}{{H}}< {10}22 {{cm}}-2) and obscured ({N}{{H}}≥slant {10}22 {{cm}}-2) AGNs, and their Swift/BAT continuum is systematically steeper than the 0.3-10 keV emission, which suggests that the presence of a high-energy cutoff is almost ubiquitous. We discuss the main X-ray spectral parameters obtained, such as the photon index, the reflection parameter, the energy of the cutoff, neutral and ionized absorbers, and the soft excess for both obscured and unobscured AGNs.

A photo-cross-linking approach to monitor folding and assembly of newly synthesized proteins in a living cell.

PubMed

Miyazaki, Ryoji; Myougo, Naomi; Mori, Hiroyuki; Akiyama, Yoshinori

2018-01-12

Many proteins form multimeric complexes that play crucial roles in various cellular processes. Studying how proteins are correctly folded and assembled into such complexes in a living cell is important for understanding the physiological roles and the qualitative and quantitative regulation of the complex. However, few methods are suitable for analyzing these rapidly occurring processes. Site-directed in vivo photo-cross-linking is an elegant technique that enables analysis of protein-protein interactions in living cells with high spatial resolution. However, the conventional site-directed in vivo photo-cross-linking method is unsuitable for analyzing dynamic processes. Here, by combining an improved site-directed in vivo photo-cross-linking technique with a pulse-chase approach, we developed a new method that can analyze the folding and assembly of a newly synthesized protein with high spatiotemporal resolution. We demonstrate that this method, named the pulse-chase and in vivo photo-cross-linking experiment (PiXie), enables the kinetic analysis of the formation of an Escherichia coli periplasmic (soluble) protein complex (PhoA). We also used our new technique to investigate assembly/folding processes of two membrane complexes (SecD-SecF in the inner membrane and LptD-LptE in the outer membrane), which provided new insights into the biogenesis of these complexes. Our PiXie method permits analysis of the dynamic behavior of various proteins and enables examination of protein-protein interactions at the level of individual amino acid residues. We anticipate that our new technique will have valuable utility for studies of protein dynamics in many organisms. © 2018 by The American Society for Biochemistry and Molecular Biology, Inc.

6. West side of Building 1001 (administration building), looking southeast ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

6. West side of Building 1001 (administration building), looking southeast - Naval Air Station Chase Field, Building 1001, Independence Street, .45 mile south of intersection of Texas State Highway & Independence Street, Beeville, Bee County, TX

5. Interior of Building 1042 (brig), cell, looking northeast ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

5. Interior of Building 1042 (brig), cell, looking northeast - Naval Air Station Chase Field, Building 1042, Ofstie Road, .6 mile South-Southeast of intersection of Texas State Highway 202 & Independence Street, Beeville, Bee County, TX

4. South side of Building 1001 (administration building), looking north ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

4. South side of Building 1001 (administration building), looking north - Naval Air Station Chase Field, Building 1001, Independence Street, .45 mile south of intersection of Texas State Highway & Independence Street, Beeville, Bee County, TX

3. East side of Building 1001 (administration building), looking west ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

3. East side of Building 1001 (administration building), looking west - Naval Air Station Chase Field, Building 1001, Independence Street, .45 mile south of intersection of Texas State Highway & Independence Street, Beeville, Bee County, TX

3. Southwest side of Building 1042 (brig), looking northeast ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

3. Southwest side of Building 1042 (brig), looking northeast - Naval Air Station Chase Field, Building 1042, Ofstie Road, .6 mile South-Southeast of intersection of Texas State Highway 202 & Independence Street, Beeville, Bee County, TX

8. Southwest side of Building 1040 (chapel), looking northeast ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

8. Southwest side of Building 1040 (chapel), looking northeast - Naval Air Station Chase Field, Building 1040, Enterprise Street, .37 mile South-Southeast of intersection of Texas State Highway 202 & Independence Street, Beeville, Bee County, TX

4. Southwest side of Building 1042 (brig), looking northeast ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

4. Southwest side of Building 1042 (brig), looking northeast - Naval Air Station Chase Field, Building 1042, Ofstie Road, .6 mile South-Southeast of intersection of Texas State Highway 202 & Independence Street, Beeville, Bee County, TX

2. Southeast side of Building 1042 (brig), looking northwest ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

2. Southeast side of Building 1042 (brig), looking northwest - Naval Air Station Chase Field, Building 1042, Ofstie Road, .6 mile South-Southeast of intersection of Texas State Highway 202 & Independence Street, Beeville, Bee County, TX

5. North side of Building 1001 (administration building), looking southeast ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

5. North side of Building 1001 (administration building), looking southeast - Naval Air Station Chase Field, Building 1001, Independence Street, .45 mile south of intersection of Texas State Highway & Independence Street, Beeville, Bee County, TX

1. Northeast side of Building 1042 (brig), looking southwest ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

1. Northeast side of Building 1042 (brig), looking southwest - Naval Air Station Chase Field, Building 1042, Ofstie Road, .6 mile South-Southeast of intersection of Texas State Highway 202 & Independence Street, Beeville, Bee County, TX

Autonomous docking ground demonstration

NASA Technical Reports Server (NTRS)

Lamkin, Steve L.; Le, Thomas Quan; Othon, L. T.; Prather, Joseph L.; Eick, Richard E.; Baxter, Jim M.; Boyd, M. G.; Clark, Fred D.; Spehar, Peter T.; Teters, Rebecca T.

1991-01-01

The Autonomous Docking Ground Demonstration is an evaluation of the laser sensor system to support the docking phase (12 ft to contact) when operated in conjunction with the guidance, navigation, and control (GN&C) software. The docking mechanism being used was developed for the Apollo/Soyuz Test Program. This demonstration will be conducted using the 6-DOF Dynamic Test System (DTS). The DTS simulates the Space Station Freedom as the stationary or target vehicle and the Orbiter as the active or chase vehicle. For this demonstration, the laser sensor will be mounted on the target vehicle and the retroflectors will be on the chase vehicle. This arrangement was chosen to prevent potential damage to the laser. The laser sensor system, GN&C, and 6-DOF DTS will be operated closed-loop. Initial conditions to simulate vehicle misalignments, translational and rotational, will be introduced within the constraints of the systems involved.

Mate-finding behaviour in Calanus marshallae Frost

PubMed Central

Tsuda, A.

1998-01-01

Mate-finding behaviour by Calanus marshallae Frost, 1974, was observed and video recorded in a 1 m diameter kreisel. Newly moulted females signal to males by depositing vertical pheromone trails many tens of centimetres long. Males search for trails along primarily horizontal trajectories. The orthogonality of signal trace and search trail trajectory maximizes the chance of intersection. Males often initiate a dance of rapid, tight turns upon encountering a pheromone trail, then waggle down it (chase swimming) to the signalling female. She jumps away after initial contact, and the male follows. Many successive approach, bump and jump sequences follow, with mating eventually ensuing. The actual copulatory clasp and spermatophore transfer were not observed, although a few instances of brief attachment and tandem swimming were seen. Male dances occur at times when chase swimming does not follow, and the function of dances is not yet known.

Toxic leucoencephalopathy after 'chasing the dragon'.

PubMed

Singh, Rajinder; Saini, Monica

2015-06-01

Toxic leucoencephalopathy (TLE) is a rare neurological complication of heroin abuse. 'Chasing the dragon' is an inhalational mode of heroin abuse that originated in Southeast Asia. Intriguingly, no cases of TLE have been reported from this region, although the inhalational mode of heroin abuse is common. We herein report the case of a middle-aged man with a history of polysubstance abuse who presented with progressive neurological symptoms and progressed to an uncommunicative state. While the initial impression was that of iatrogenic parkinsonism, diffuse leucoencephalopathy with sparing of the cerebellum was noted on magnetic resonance imaging. In view of his history of inhalational heroin abuse close to the onset of the neurological symptoms, a diagnosis of TLE was made. No clinical improvement was noted with administration of a dopaminergic agent. This is the first known case of delayed TLE following heroin inhalation from Southeast Asia with the unusual feature of cerebellar sparing.

Resin bleed improvement on surface mount semiconductor device

NASA Astrophysics Data System (ADS)

Rajoo, Indra Kumar; Tahir, Suraya Mohd; Aziz, Faieza Abdul; Shamsul Anuar, Mohd

2018-04-01

Resin bleed is a transparent layer of epoxy compound which occurs during molding process but is difficult to be detected after the molding process. Resin bleed on the lead on the unit from the focused package, SOD123, can cause solderability failure at end customer. This failed unit from the customer will be considered as a customer complaint. Generally, the semiconductor company has to perform visual inspection after the plating process to detect resin bleed. Mold chase with excess hole, split cavity & stepped design ejector pin hole have been found to be the major root cause of resin bleed in this company. The modifications of the mold chase, changing of split cavity to solid cavity and re-design of the ejector pin proposed were derived after a detailed study & analysis conducted to arrive at these solutions. The solutions proposed have yield good results during the pilot run with zero (0) occurrence of resin bleed for 3 consecutive months.

An Unsupervised Approach for Extraction of Blood Vessels from Fundus Images.

PubMed

Dash, Jyotiprava; Bhoi, Nilamani

2018-04-26

Pathological disorders may happen due to small changes in retinal blood vessels which may later turn into blindness. Hence, the accurate segmentation of blood vessels is becoming a challenging task for pathological analysis. This paper offers an unsupervised recursive method for extraction of blood vessels from ophthalmoscope images. First, a vessel-enhanced image is generated with the help of gamma correction and contrast-limited adaptive histogram equalization (CLAHE). Next, the vessels are extracted iteratively by applying an adaptive thresholding technique. At last, a final vessel segmented image is produced by applying a morphological cleaning operation. Evaluations are accompanied on the publicly available digital retinal images for vessel extraction (DRIVE) and Child Heart And Health Study in England (CHASE_DB1) databases using nine different measurements. The proposed method achieves average accuracies of 0.957 and 0.952 on DRIVE and CHASE_DB1 databases respectively.

Fringe chasing by three-point spatial phase shifting for discrimination of the motion direction in the long-range homodyne laser Doppler vibrometry

NASA Astrophysics Data System (ADS)

Daemi, Mohammad Hossein; Rasouli, Saifollah

2018-07-01

In this work, a three-point spatial phase shifting (SPS) method is implemented for chasing of the moving interference fringes in the homodyne laser Doppler vibrometry (HoLDV). By the use of SPS method, we remove disability of the HoLDV in the discrimination of the motion direction for long-range displacements. From the phase increments histogram, phase unwrapping tolerance value is selected, and adequacy of the data acquisition rate and required bandwidth limit are determined. Also in this paper, a detailed investigation on the effect of detectors positioning errors and influence of the Gaussian profile of the interfering beams on the measurements are presented. Performance of the method is verified by measuring a given harmonic vibration produced by a loudspeaker. Also, by the proposed method, vibration of mounting system of a disk laser gain medium is characterized.

Constraining chameleon field theories using the GammeV afterglow experiments

DOE Office of Scientific and Technical Information (OSTI.GOV)

Upadhye, A.; /Chicago U., EFI /KICP, Chicago; Steffen, J.H.

2009-11-01

The GammeV experiment has constrained the couplings of chameleon scalar fields to matter and photons. Here we present a detailed calculation of the chameleon afterglow rate underlying these constraints. The dependence of GammeV constraints on various assumptions in the calculation is studied. We discuss GammeV-CHASE, a second-generation GammeV experiment, which will improve upon GammeV in several major ways. Using our calculation of the chameleon afterglow rate, we forecast model-independent constraints achievable by GammeV-CHASE. We then apply these constraints to a variety of chameleon models, including quartic chameleons and chameleon dark energy models. The new experiment will be able to probemore » a large region of parameter space that is beyond the reach of current tests, such as fifth force searches, constraints on the dimming of distant astrophysical objects, and bounds on the variation of the fine structure constant.« less

Coplanar tail-chase aerial combat as a differential game

NASA Technical Reports Server (NTRS)

Merz, A. W.; Hague, D. S.

1977-01-01

A reduced-order version of the one-on-one aerial combat problem is studied as a pursuit-evasion differential game. The coplanar motion takes place at given speeds and given maximum available turn rates, and is described by three state equations which are equivalent to the range, bearing, and heading of one aircraft relative to the other. The purpose of the study is to determine those relative geometries from which either aircraft can be guaranteed a win, regardless of the maneuver strategies of the other. Termination is specified by the tail-chase geometry, at which time the roles of pursuer and evader are known. The roles are found in general, together with the associated optimal turn maneuvers, by solution of the differential game of kind. For the numerical parameters chosen, neither aircraft can win from the majority of possible initial conditions if the other turns optimally in certain critical geometries.

Chasing The 'Like': Adolescent Use Of Social Networking Sites In Australia.

PubMed

la Sala, Louise; Skues, Jason; Wise, Lisa; Theiler, Stephen

2015-01-01

The current study investigated how adolescents behave on Social Networking Sites (SNSs) and how they interpret the feedback they receive online from others. Thirty-four Australian adolescents (26 girls, 8 boys) aged 13 to 17 years participated in the study. Five semi-structured focus groups (3 mixed groups, 2 all-girl groups) were conducted to explore how adolescents perceive their own and others' SNS behaviours, the motivation underlying these behaviours, and the expected outcomes related to particular behaviours. Teenagers reported that they spend a good deal of time planning their SNS posts, felt that the information they posted was a true reflection of them as a person, and thus interpreted feedback ("likes") as measuring their self-worth. In contrast, some teenagers were perceived as "chasing the like" for status and popularity while not caring about how accurately their posts represented them as a person. A potential gender bias in these findings is discussed.

[Occipital neuralgia with visual obscurations: a case report].

PubMed

Selekler, Hamit Macit; Dündar, Gülmine; Kutlu, Ayşe

2010-07-01

Vertigo, dizziness and visual blurring have been reported in painful conditions in trigeminal innervation zones such as in idiopathic stabbing headache, supraorbital neuralgia or trigeminal nerve ophthalmic branch neuralgia. Although not common, pain in occipital neuralgia can spread through the anterior parts of the head. In this article, we present a case whose occipital neuralgiform paroxysms spread to the ipsilateral eye with simultaneous visual obscuration; the mechanisms of propagation and visual obscuration are discussed.

Curriculum Testing on the Persistent Fringes: Neoliberal Policy and the New Regime of Title I High School Reform

ERIC Educational Resources Information Center

Sturges, Keith M.

2015-01-01

Neoliberal policies have opened the door to a steady stream of contract providers who assist struggling schools while producing market-ready reforms. This ethnographic example of Allport High School illustrates how constant aid, in combination with internal market expansion, destabilizes school structures, obscures curricula, and transfers local…

Obscured AGN at z ~ 1 from the zCOSMOS-Bright Survey. I. Selection and optical properties of a [Ne v]-selected sample

NASA Astrophysics Data System (ADS)

Mignoli, M.; Vignali, C.; Gilli, R.; Comastri, A.; Zamorani, G.; Bolzonella, M.; Bongiorno, A.; Lamareille, F.; Nair, P.; Pozzetti, L.; Lilly, S. J.; Carollo, C. M.; Contini, T.; Kneib, J.-P.; Le Fèvre, O.; Mainieri, V.; Renzini, A.; Scodeggio, M.; Bardelli, S.; Caputi, K.; Cucciati, O.; de la Torre, S.; de Ravel, L.; Franzetti, P.; Garilli, B.; Iovino, A.; Kampczyk, P.; Knobel, C.; Kovač, K.; Le Borgne, J.-F.; Le Brun, V.; Maier, C.; Pellò, R.; Peng, Y.; Perez Montero, E.; Presotto, V.; Silverman, J. D.; Tanaka, M.; Tasca, L.; Tresse, L.; Vergani, D.; Zucca, E.; Bordoloi, R.; Cappi, A.; Cimatti, A.; Koekemoer, A. M.; McCracken, H. J.; Moresco, M.; Welikala, N.

2013-08-01

Aims: The application of multi-wavelength selection techniques is essential for obtaining a complete and unbiased census of active galactic nuclei (AGN). We present here a method for selecting z ~ 1 obscured AGN from optical spectroscopic surveys. Methods: A sample of 94 narrow-line AGN with 0.65 < z < 1.20 was selected from the 20k-Bright zCOSMOS galaxy sample by detection of the high-ionization [Ne v] λ3426 line. The presence of this emission line in a galaxy spectrum is indicative of nuclear activity, although the selection is biased toward low absorbing column densities on narrow-line region or galactic scales. A similar sample of unobscured (type 1 AGN) was collected applying the same analysis to zCOSMOS broad-line objects. This paper presents and compares the optical spectral properties of the two AGN samples. Taking advantage of the large amount of data available in the COSMOS field, the properties of the [Ne v]-selected type 2 AGN were investigated, focusing on their host galaxies, X-ray emission, and optical line-flux ratios. Finally, a previously developed diagnostic, based on the X-ray-to-[Ne v] luminosity ratio, was exploited to search for the more heavily obscured AGN. Results: We found that [Ne v]-selected narrow-line AGN have Seyfert 2-like optical spectra, although their emission line ratios are diluted by a star-forming component. The ACS morphologies and stellar component in the optical spectra indicate a preference for our type 2 AGN to be hosted in early-type spirals with stellar masses greater than 109.5 - 10 M⊙, on average higher than those of the galaxy parent sample. The fraction of galaxies hosting [Ne v]-selected obscured AGN increases with the stellar mass, reaching a maximum of about 3% at ≈2 × 1011 M⊙. A comparison with other selection techniques at z ~ 1, namely the line-ratio diagnostics and X-ray detections, shows that the detection of the [Ne v] λ3426 line is an effective method for selecting AGN in the optical band, in particular the most heavily obscured ones, but cannot provide a complete census of type 2 AGN by itself. Finally, the high fraction of [Ne v]-selected type 2 AGN not detected in medium-deep (≈100-200 ks) Chandra observations (67%) is suggestive of the inclusion of Compton-thick (i.e., with NH > 1024 cm-2) sources in our sample. The presence of a population of heavily obscured AGN is corroborated by the X-ray-to-[Ne v] ratio; we estimated, by means of an X-ray stacking technique and simulations, that the Compton-thick fraction in our sample of type 2 AGN is 43 ± 4% (statistical errors only), which agrees well with standard assumptions by XRB synthesis models.

Phosphatidylserine translocation to the mitochondrion is an ATP-dependent process in permeabilized animal cells

DOE Office of Scientific and Technical Information (OSTI.GOV)

Voelker, D.R.

1989-12-01

Chinese hamster ovary (CHO-K1) cells were pulse labeled with ({sup 3}H)serine, and the synthesis of phosphatidyl({sup 3}H)ethanolamine from phosphatidyl({sup 3}H)serine during the subsequent chase was used as a measure of lipid translocation to the mitochondria. When the CHO-K1 cells were pulse labeled and subsequently permeabilized with 50 {mu}g of saponin per ml, there was no significant turnover of nascent phosphatidyl({sup 3}H)serine to form phosphatidyl({sup 3}H)ethanolamine during an ensuring chase. Supplementation of the permeabilized cells with 2 mM ATP resulted in significant phosphatidyl({sup 3}H)ethanolamine synthesis (83% of that found in intact cells) from phosphatidyl({sup 3}H)serine during a subsequent 2-hr chase. Phosphatidyl({supmore » 3}H)ethanolamine synthesis essentially ceased after 2 hr in the permeabilized cells. The translocation-dependent synthesis of phosphatidyl({sup 3}H)ethanolamine was a saturable process with respect to ATP concentration in permeabilized cells. The conversion of phosphatidyl({sup 3}H)serine to phosphatidyl({sup 3}H)ethanolamine did not occur in saponin-treated cultures supplemented with 2 mM AMP, 2 mM 5{prime}-adenylyl imidodiphosphate, or apyrase plus 2 mM ATP. ATP was the most effective nucleotide, but the addition of GTP, CTP, UTP, and ADP also supported the translocation-dependent synthesis of phosphatidyl({sup 3}H)ethanolamine albeit to a lesser extent. These data provide evidence that the interorganelle translocation of phosphatidylserine requires ATP and is largely independent of soluble cytosolic proteins.« less

Smoking tobacco along with marijuana increases symptoms of cannabis dependence

PubMed Central

Ream, Geoffrey L.; Benoit, Ellen; Johnson, Bruce D.; Dunlap, Eloise

2008-01-01

Aim User practices/rituals that involve concurrent use of tobacco and marijuana – smoking blunts and “chasing” marijuana with tobacco – are hypothesized to increase cannabis dependence symptoms. Design Ethnographers administered group surveys to a diverse, purposive sample of marijuana users who appeared to be 17–35 years old. Setting New York City, including non-impoverished areas of Manhattan, the transitional area of East Village/Lower East Side, low-income areas of northern Manhattan and South Bronx, and diverse areas of Brooklyn and Queens. Participants 481 marijuana users ages 14–35, 57% male, 43% female; 27% White, 30% Black, 19% Latino, 5% Asian, 20% of other/multiple race. Measurements Among many other topics, group surveys measured cannabis dependence symptoms; frequencies of chasing, blunt smoking, joint/pipe smoking, using marijuana while alone, and general tobacco use; and demographic factors. Findings Blunt smoking and chasing marijuana with tobacco were each uniquely associated with five of the seven cannabis dependence symptoms. Across symptoms, predicted odds were 2.4–4.1 times greater for participants who smoked blunts on all 30 of the past 30 days than for participants who did not smoke blunts in the past 30 days. Significant increases in odds over the whole range of the five-point chasing frequency measure (from never to always) ranged from 3.4 times to 5.1 times. Conclusions Using tobacco with marijuana – smoking blunts and “chasing” marijuana with tobacco – contributes to cannabis dependence symptoms. Treatment for cannabis dependence may be more effective it addresses the issue of concurrent tobacco use. PMID:18339491

Obscuration-dependent Evolution of Active Galactic Nuclei

NASA Astrophysics Data System (ADS)

Buchner, Johannes; Georgakakis, Antonis; Nandra, Kirpal; Brightman, Murray; Menzel, Marie-Luise; Liu, Zhu; Hsu, Li-Ting; Salvato, Mara; Rangel, Cyprian; Aird, James; Merloni, Andrea; Ross, Nicholas

2015-04-01

We aim to constrain the evolution of active galactic nuclei (AGNs) as a function of obscuration using an X-ray-selected sample of ~2000 AGNs from a multi-tiered survey including the CDFS, AEGIS-XD, COSMOS, and XMM-XXL fields. The spectra of individual X-ray sources are analyzed using a Bayesian methodology with a physically realistic model to infer the posterior distribution of the hydrogen column density and intrinsic X-ray luminosity. We develop a novel non-parametric method that allows us to robustly infer the distribution of the AGN population in X-ray luminosity, redshift, and obscuring column density, relying only on minimal smoothness assumptions. Our analysis properly incorporates uncertainties from low count spectra, photometric redshift measurements, association incompleteness, and the limited sample size. We find that obscured AGNs with N H > 1022 cm-2 account for {77}+4-5% of the number density and luminosity density of the accretion supermassive black hole population with L X > 1043 erg s-1, averaged over cosmic time. Compton-thick AGNs account for approximately half the number and luminosity density of the obscured population, and {38}+8-7% of the total. We also find evidence that the evolution is obscuration dependent, with the strongest evolution around N H ≈ 1023 cm-2. We highlight this by measuring the obscured fraction in Compton-thin AGNs, which increases toward z ~ 3, where it is 25% higher than the local value. In contrast, the fraction of Compton-thick AGNs is consistent with being constant at ≈35%, independent of redshift and accretion luminosity. We discuss our findings in the context of existing models and conclude that the observed evolution is, to first order, a side effect of anti-hierarchical growth.

Restoration of US Aid to Fiji: The Advantages of Obscurity

DTIC Science & Technology

1991-12-20

RESTORATION OF US AID TO FIJI: THE ADVANTAGES OF OBSCURITY Elizabeth McKune NWC Class of 󈨠 December 20, 1991 Report Documentation Page Form...COVERED 20-12-1991 to 20-12-1991 4. TITLE AND SUBTITLE Restoration of US Aid to Fiji: The Advantages of Obscurity 5a. CONTRACT NUMBER 5b...unimportance were advantageous . PHASE ONE Background In the context of the South Pacific, however, Fiji was prominent, frequently cited as a model

76 FR 58805 - Notice of Availability of Environmental Assessment; Jonathan and Jayne Chase

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-22

... hydropower project exemption for the Troy Hydroelectric Project, to be located on the Missisquoi River, in the Town of Troy in Orleans County, Vermont, and has prepared an Environmental Assessment (EA). In the...

4. Northeast side of Building 1009, (enlisted waves' barracks), looking ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

4. Northeast side of Building 1009, (enlisted waves' barracks), looking southwest - Naval Air Station Chase Field, Building 1009, Essex Street, .68 mile South-southeast of intersection of Texas State Highway 202 & Independence Street, Beeville, Bee County, TX

1. Overview of Building 1009, (enlisted waves' barracks), looking east ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

1. Overview of Building 1009, (enlisted waves' barracks), looking east - Naval Air Station Chase Field, Building 1009, Essex Street, .68 mile South-southeast of intersection of Texas State Highway 202 & Independence Street, Beeville, Bee County, TX

2. Southwest side of Building 1009, (enlisted waves' barracks), looking ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

2. Southwest side of Building 1009, (enlisted waves' barracks), looking northeast - Naval Air Station Chase Field, Building 1009, Essex Street, .68 mile South-southeast of intersection of Texas State Highway 202 & Independence Street, Beeville, Bee County, TX

3. Southwest side of quarters R (commanding officer's quarters), looking ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

3. Southwest side of quarters R (commanding officer's quarters), looking east - Naval Air Station Chase Field, Quarters R, Essex Street, .43 mile South-Southeast of intersection of Texas State Highway 202 & Independence Street, Beeville, Bee County, TX

3. Northwest side of Building 1009, (enlisted waves' barracks), looking ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

3. Northwest side of Building 1009, (enlisted waves' barracks), looking southeast - Naval Air Station Chase Field, Building 1009, Essex Street, .68 mile South-southeast of intersection of Texas State Highway 202 & Independence Street, Beeville, Bee County, TX

4. Northeast side of Building 1015 (land plane hangar), looking ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

4. Northeast side of Building 1015 (land plane hangar), looking southwest - Naval Air Station Chase Field, Building 1015, Byrd Street, .82 mile South-southeast of intersection of Texas State Highway 202 & Independence Street, Beeville, Bee County, TX

5. Southeast side of Building 1015 (land plane hangar), looking ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

5. Southeast side of Building 1015 (land plane hangar), looking northwest - Naval Air Station Chase Field, Building 1015, Byrd Street, .82 mile South-southeast of intersection of Texas State Highway 202 & Independence Street, Beeville, Bee County, TX

3. Northwest side of Building 1015 (land plane hangar), looking ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

3. Northwest side of Building 1015 (land plane hangar), looking east - Naval Air Station Chase Field, Building 1015, Byrd Street, .82 mile South-southeast of intersection of Texas State Highway 202 & Independence Street, Beeville, Bee County, TX

6. Interior of quarters (executive officer's quarters), living room, looking ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

6. Interior of quarters (executive officer's quarters), living room, looking west - Naval Air Station Chase Field, Quarters S, Essex Street, .45 mile South-Southeast of intersection of Texas State Highway 202 & Independence Street, Beeville, Bee County, TX

9. Interior of Building 1001 (administration building), Room 204, vault, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

9. Interior of Building 1001 (administration building), Room 204, vault, looking east - Naval Air Station Chase Field, Building 1001, Independence Street, .45 mile south of intersection of Texas State Highway & Independence Street, Beeville, Bee County, TX

1. North side of quarters (executive officer's quarters), looking southeast ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

1. North side of quarters (executive officer's quarters), looking southeast - Naval Air Station Chase Field, Quarters S, Essex Street, .45 mile South-Southeast of intersection of Texas State Highway 202 & Independence Street, Beeville, Bee County, TX

6. Detail of southeast side of Building 1040 (chapel), looking ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

6. Detail of southeast side of Building 1040 (chapel), looking northwest - Naval Air Station Chase Field, Building 1040, Enterprise Street, .37 mile South-Southeast of intersection of Texas State Highway 202 & Independence Street, Beeville, Bee County, TX

6. Overview of Building 1009, (enlisted waves' barracks), looking east ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

6. Overview of Building 1009, (enlisted waves' barracks), looking east - Naval Air Station Chase Field, Building 1009, Essex Street, .68 mile South-southeast of intersection of Texas State Highway 202 & Independence Street, Beeville, Bee County, TX

9. Interior of Building 1009, view of central hall, looking ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

9. Interior of Building 1009, view of central hall, looking southeast - Naval Air Station Chase Field, Building 1009, Essex Street, .68 mile South-southeast of intersection of Texas State Highway 202 & Independence Street, Beeville, Bee County, TX

2. Southwest side of Building 1015 (land plane hangar), looking ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

2. Southwest side of Building 1015 (land plane hangar), looking northeast - Naval Air Station Chase Field, Building 1015, Byrd Street, .82 mile South-southeast of intersection of Texas State Highway 202 & Independence Street, Beeville, Bee County, TX

5. East side of quarters (executive officer's quarters), looking west ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

5. East side of quarters (executive officer's quarters), looking west - Naval Air Station Chase Field, Quarters S, Essex Street, .45 mile South-Southeast of intersection of Texas State Highway 202 & Independence Street, Beeville, Bee County, TX

1. Northeast side of Quarters R (commanding officer's quarters), looking ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

1. Northeast side of Quarters R (commanding officer's quarters), looking west - Naval Air Station Chase Field, Quarters R, Essex Street, .43 mile South-Southeast of intersection of Texas State Highway 202 & Independence Street, Beeville, Bee County, TX

2. West side of quarters (executive officer's quarters), looking east ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

2. West side of quarters (executive officer's quarters), looking east - Naval Air Station Chase Field, Quarters S, Essex Street, .45 mile South-Southeast of intersection of Texas State Highway 202 & Independence Street, Beeville, Bee County, TX

2. Southeast side of Quarters R (commanding officer's quarters), looking ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

2. Southeast side of Quarters R (commanding officer's quarters), looking northwest - Naval Air Station Chase Field, Quarters R, Essex Street, .43 mile South-Southeast of intersection of Texas State Highway 202 & Independence Street, Beeville, Bee County, TX

4. Northwest side of Quarters R (commanding officer's quarters), looking ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

4. Northwest side of Quarters R (commanding officer's quarters), looking southeast - Naval Air Station Chase Field, Quarters R, Essex Street, .43 mile South-Southeast of intersection of Texas State Highway 202 & Independence Street, Beeville, Bee County, TX

7. Detail of southwest side of Building 1040 (gym), looking ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

7. Detail of southwest side of Building 1040 (gym), looking northeast - Naval Air Station Chase Field, Building 1040, Enterprise Street, .37 mile South-Southeast of intersection of Texas State Highway 202 & Independence Street, Beeville, Bee County, TX

6. Interior of Building 1015 (land plane hangar), looking north ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

6. Interior of Building 1015 (land plane hangar), looking north - Naval Air Station Chase Field, Building 1015, Byrd Street, .82 mile South-southeast of intersection of Texas State Highway 202 & Independence Street, Beeville, Bee County, TX

1. Overview of Building 1015 (land plane hanger), looking east ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

1. Overview of Building 1015 (land plane hanger), looking east - Naval Air Station Chase Field, Building 1015, Byrd Street, .82 mile South-southeast of intersection of Texas State Highway 202 & Independence Street, Beeville, Bee County, TX

4. South side of quarters (executive officer's quarters), looking north ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

4. South side of quarters (executive officer's quarters), looking north - Naval Air Station Chase Field, Quarters S, Essex Street, .45 mile South-Southeast of intersection of Texas State Highway 202 & Independence Street, Beeville, Bee County, TX

1. Overview of Building 1040 (auditorium/gym/chapel), looking north Naval ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

1. Overview of Building 1040 (auditorium/gym/chapel), looking north - Naval Air Station Chase Field, Building 1040, Enterprise Street, .37 mile South-Southeast of intersection of Texas State Highway 202 & Independence Street, Beeville, Bee County, TX

5. Southeast side of Building 1009, (enlisted waves' barracks), looking ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

5. Southeast side of Building 1009, (enlisted waves' barracks), looking west - Naval Air Station Chase Field, Building 1009, Essex Street, .68 mile South-southeast of intersection of Texas State Highway 202 & Independence Street, Beeville, Bee County, TX

3. Southwest side of quarters (executive officer's quarters), looking northeast ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

3. Southwest side of quarters (executive officer's quarters), looking northeast - Naval Air Station Chase Field, Quarters S, Essex Street, .45 mile South-Southeast of intersection of Texas State Highway 202 & Independence Street, Beeville, Bee County, TX

Biogenesis of the rat hepatocyte plasma membrane in vivo: comparison of the pathways taken by apical and basolateral proteins using subcellular fractionation

PubMed Central

1987-01-01

We have used pulse-chase metabolic radiolabeling with L-[35S]methionine in conjunction with subcellular fractionation and specific protein immunoprecipitation techniques to compare the posttranslational transport pathways taken by endogenous domain-specific integral proteins of the rat hepatocyte plasma membrane in vivo. Our results suggest that both apical (HA 4, dipeptidylpeptidase IV, and aminopeptidase N) and basolateral (CE 9 and the asialoglycoprotein receptor [ASGP-R]) proteins reach the hepatocyte plasma membrane with similar kinetics. The mature molecular mass form of each of these proteins reaches its maximum specific radioactivity in a purified hepatocyte plasma membrane fraction after only 45 min of chase. However, at this time, the mature radiolabeled apical proteins are not associated with vesicles derived from the apical domain of the hepatocyte plasma membrane, but instead are associated with vesicles which, by several criteria, appear to be basolateral plasma membrane. These vesicles: (a) fractionate like basolateral plasma membrane in sucrose density gradients and in free-flow electrophoresis; (b) can be separated from the bulk of the likely organellar contaminants, including membranes derived from the late Golgi cisternae, transtubular network, and endosomes; (c) contain the proven basolateral constituents CE 9 and the ASGP-R, as judged by vesicle immunoadsorption using fixed Staphylococcus aureus cells and anti-ASGP-R antibodies; and (d) are oriented with their ectoplasmic surfaces facing outward, based on the results of vesicle immunoadsorption experiments using antibodies specific for the ectoplasmic domain of the ASGP-R. Only at times of chase greater than 45 min do significant amounts of the mature radiolabeled apical proteins arrive at the apical domain, and they do so at different rates. Approximate half-times for arrival are in the range of 90-120 min for aminopeptidase N and dipeptidylpeptidase IV whereas only 15-20% of the mature radiolabeled HA 4 associated with the hepatocyte plasma membrane fraction has become apical even after 150 min of chase. Our results suggest a mechanism for hepatocyte plasma membrane biogenesis in vivo in which all integral plasma membrane proteins are shipped first to the basolateral domain, followed by the specific retrieval and transport of apical proteins to the apical domain at distinct rates. PMID:3654750

NuSTAR Observations of Heavily Obscured Quasars Selected by WISE

NASA Astrophysics Data System (ADS)

Yan, Wei

2017-08-01

A key goal of the Nuclear Spectroscopic Telescope Array (NuSTAR) program is to find and characterize heavily obscured quasars, luminous accreting supermassive black holes hidden by gas and dust. Based on mid-infrared (IR) photometry from Wide-Field Infrared Survey Explorer (WISE) and optical photometry from the Sloan Digital Sky Surveys, we have selected a large population of obscured quasars; here we report the NuSTAR observations of four WISE-selected heavily obscured quasars for which we have optical spectroscopy from the Southern African Large Telescope and KECK Telescope. Three of four objects are undetected with NuSTAR, while the fourth has only a marginal detection. We confirm our objects have observed hard X-ray (10-40 keV) luminosities at or below ~1043 erg s-1. We compare IR and X-ray luminosities to obtain estimates of hydrogen column NH based on the suppression of the hard X-ray emission. We estimate NH to be at or greater than 1025 cm-2, confirming that WISE and optical selection can identify very heavily obscured quasars that may be missed in X-ray surveys.

Quantitative Measurement of GPCR Endocytosis via Pulse-Chase Covalent Labeling

PubMed Central

Fujishiro, Mitsuhiro; Okamura, Tomohisa; Fujio, Keishi; Okazaki, Hiroaki; Nomura, Seitaro; Takeda, Norifumi; Harada, Mutsuo; Toko, Haruhiro; Takimoto, Eiki; Akazawa, Hiroshi; Morita, Hiroyuki; Suzuki, Jun-ichi; Yamazaki, Tsutomu; Yamamoto, Kazuhiko; Komuro, Issei; Yanagisawa, Masashi

2015-01-01

G protein-coupled receptors (GPCRs) play a critical role in many physiological systems and represent one of the largest families of signal-transducing receptors. The number of GPCRs at the cell surface regulates cellular responsiveness to their cognate ligands, and the number of GPCRs, in turn, is dynamically controlled by receptor endocytosis. Recent studies have demonstrated that GPCR endocytosis, in addition to affecting receptor desensitization and resensitization, contributes to acute G protein-mediated signaling. Thus, endocytic GPCR behavior has a significant impact on various aspects of physiology. In this study, we developed a novel GPCR internalization assay to facilitate characterization of endocytic GPCR behavior. We genetically engineered chimeric GPCRs by fusing HaloTag (a catalytically inactive derivative of a bacterial hydrolase) to the N-terminal end of the receptor (HT-GPCR). HaloTag has the ability to form a stable covalent bond with synthetic HaloTag ligands that contain fluorophores or a high-affinity handle (such as biotin) and the HaloTag reactive linker. We selectively labeled HT-GPCRs at the cell surface with a HaloTag PEG ligand, and this pulse-chase covalent labeling allowed us to directly monitor the relative number of internalized GPCRs after agonist stimulation. Because the endocytic activities of GPCR ligands are not necessarily correlated with their agonistic activities, applying this novel methodology to orphan GPCRs, or even to already characterized GPCRs, will increase the likelihood of identifying currently unknown ligands that have been missed by conventional pharmacological assays. PMID:26020647

Highway measurements of vehicle-induced turbulence (VIT) and enhanced mixing in the surface layer

NASA Astrophysics Data System (ADS)

Miller, S. J.; Gordon, M.; Staebler, R. M.; Li-Chee-Ming, J.; Taylor, P.

2016-12-01

Motor vehicles generate vehicle-induced turbulence (VIT) while in motion, which affects the mixing and transport of emitted trace gases, heat and momentum. During July, 2016 a 40Hz sonic anemometer (ATI) and a co-located 20Hz open path CO2/H2O gas analyzer (LICOR) were assembled and driven on highways in the Greater Toronto Area. An ultra-high sensitivity aerosol spectrometer was employed to measure the total number concentration of particles between 60 and 1000nm at the position of the gas analyzer and sonic anemometer. A video camera with GPS capabilities was also utilized to assess the surrounding features while chasing a specific vehicle type. The following distance of each chased vehicle is calculated as a function of pixel location, with the back edge of each followed vehicle being identified as the initial contrast between the vehicle's shadow and the roadway. Combining the sonic anemometer data with the GPS data allows turbulence statistics to be developed and correlations with vehicle type and following distance to be examined. Vehicle-induced turbulence is assessed using turbulent kinetic energy (TKE), a measure of turbulent mixing, which maximizes near the followed vehicle and decreases with increasing following distance. Vehicle exhaust plumes are identified using the measured CO2 concentration. The CO2 concentration data in conjunction with TKE and turbulent fluxes are used to explore the potential impacts of vehicle-induced turbulence on atmospheric mixing within the surface layer.

Proceedings of the 1990 Scientific Conference on Obscuration and Aerosol Research Held in Aberdeen Proving Ground, Maryland on 25 - 28 June 1990

DTIC Science & Technology

1991-06-01

UNDEREXPANDED SONIC JETS B.J. Jurclk and J. Brock ....... ................. .15 A NEW STATISTICAL MEASURE OF PLUME OBSCURATION EFFECTIVENESS: MEAN WAITING TIME...UNDEREXPANDED SONIC JETS B. J. Jurcik and J. Brock Chemical Engineering Department University of Texas, Austin, Texas 78712 RECENT PUBLICATIONS, SUBMITTALS...Obscuration and Aerosol Research, CRDEC, U. S. Army, 1990 (with J. Carls) "Aerosol jet etching", Aerosol Sci. Tech.,12,842-856 (1990) (with Y. L. Chen

Compton-thick AGN at high and low redshift

NASA Astrophysics Data System (ADS)

Akylas, A.; Georgantopoulos, I.; Corral, A.; Ranalli, P.; Lanzuisi, G.

2017-10-01

The most obscured sources detected in X-ray surveys, the Compton-thick AGN present great interest both because they represent the hidden side of accretion but also because they may signal the AGN birth. We analyse the NUSTAR observations from the serendipitous observations in order to study the Compton-thick AGN at the deepest possible ultra-hard band (>10 keV). We compare our results with our SWIFT/BAT findings in the local Universe, as well as with our results in the CDFS and COSMOS fields. We discuss the comparison with X-ray background synthesis models finding that a low fraction of Compton-thick sources (about 15 per cent of the obscured population) is compatible with both the 2-10keV band results and those at harder energies.

Peering Through the Dust: NuSTAR Observations of Two First-2Mass Red Quasars

NASA Technical Reports Server (NTRS)

Lamassa, Stephanie M.; Ricarte, Angelo; Glikman, Eilat; Urry, C. Megan; Stern, Daniel; Yaqoob, Tahir; Lansbury, George B.; Civano, Francesca; Boggs, Steve E.; Zhang, Will

2016-01-01

Some reddened quasars appear to be transitional objects in the paradigm of merger-induced black hole growth/ galaxy evolution, where a heavily obscured nucleus starts to be unveiled by powerful quasar winds evacuating the surrounding cocoon NuSTAR and XMM-Newton/Chandra observations of FIRST-2MASS-selected red quasars F2M 0830+3759 and F2M 1227+3214. We find that though F2M 0830 +3759 is moderately obscured N(sub H) = (2.1 +/- 0.2) x 10 (exp 22) per square centimeter) and F2M 1227+3214 is mildly absorbed (N(sub H),Z =3.4(+0.8/-0.7) X 10(exp -2) along the line of sight, heavier global obscuration may be present in both sources, with N(sub H) = 3.7 (+4.1/-2.6) X 10 (exp 23) per square centimeter) and less than 5.5 X 10(exp 23) per square centimeter) for F2M 0830+3759 and F2M 1227+ 3214, respectively. F2M 0830+3759 also has an excess of soft X-ray emission below 1 of dust and gas. Hard X-ray observations are able to peer through this gas and dust, revealing the properties of circumnuclear obscuration. Here, we present keV, which is well accommodated by a model where 7% of the intrinsic X-ray emission from the active galactic nucleus (AGN) is scattered into the line of sight. While F2M 1227+3214 has a dust-to-gas ratio (E(B - V)/NH) consistent with the Galactic value, the value of E(B - V)/NH for F2M 0830+3759 is lower than the Galactic standard, consistent with the paradigm that the dust resides on galactic scales while the X-ray reprocessing gas originates within the dust sublimation zone of the broad-line region. The X-ray and 6.1 µm luminosities of these red quasars are consistent with the empirical relations derived for high-luminosity, unobscured quasars, extending the parameter space of obscured AGNs previously observed by NuSTAR to higher luminosities.

7. Interior of Building 1015 (land plane hangar), structural detail, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

7. Interior of Building 1015 (land plane hangar), structural detail, looking northeast - Naval Air Station Chase Field, Building 1015, Byrd Street, .82 mile South-southeast of intersection of Texas State Highway 202 & Independence Street, Beeville, Bee County, TX

2. Southeast side of Building 1040 (auditorium/gym/chapel), looking northwest ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

2. Southeast side of Building 1040 (auditorium/gym/chapel), looking northwest - Naval Air Station Chase Field, Building 1040, Enterprise Street, .37 mile South-Southeast of intersection of Texas State Highway 202 & Independence Street, Beeville, Bee County, TX

7. Staircase on south side of Building 1009, (enlisted waves' ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

7. Staircase on south side of Building 1009, (enlisted waves' barracks), looking southeast - Naval Air Station Chase Field, Building 1009, Essex Street, .68 mile South-southeast of intersection of Texas State Highway 202 & Independence Street, Beeville, Bee County, TX

8. Interior of Building 1015 (land plane hangar), structural detail, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

8. Interior of Building 1015 (land plane hangar), structural detail, looking northeast - Naval Air Station Chase Field, Building 1015, Byrd Street, .82 mile South-southeast of intersection of Texas State Highway 202 & Independence Street, Beeville, Bee County, TX

5. Interior of Quarters R (commanding officer's quarters), living room, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

5. Interior of Quarters R (commanding officer's quarters), living room, looking northwest - Naval Air Station Chase Field, Quarters R, Essex Street, .43 mile South-Southeast of intersection of Texas State Highway 202 & Independence Street, Beeville, Bee County, TX

3. Southeast side of Building 1040 (auditorium/gym/chapel), looking northwest ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

3. Southeast side of Building 1040 (auditorium/gym/chapel), looking northwest - Naval Air Station Chase Field, Building 1040, Enterprise Street, .37 mile South-Southeast of intersection of Texas State Highway 202 & Independence Street, Beeville, Bee County, TX

4. Northeast side of Building 1040 (auditorium/gym/chapel), looking southwest ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

4. Northeast side of Building 1040 (auditorium/gym/chapel), looking southwest - Naval Air Station Chase Field, Building 1040, Enterprise Street, .37 mile South-Southeast of intersection of Texas State Highway 202 & Independence Street, Beeville, Bee County, TX

5. Northwest side of Building 1040 (auditorium/gym/chapel), looking south ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

5. Northwest side of Building 1040 (auditorium/gym/chapel), looking south - Naval Air Station Chase Field, Building 1040, Enterprise Street, .37 mile South-Southeast of intersection of Texas State Highway 202 & Independence Street, Beeville, Bee County, TX

78 FR 1853 - EH California Hydro, LLC; Notice of Preliminary Permit Application Accepted for Filing and...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-09

... tailrace. Applicant Contact: Mr. John R. Collins, EH California Hydro, LLC, 5425 Wisconsin Avenue, Suite 600, Chevy Chase, Maryland 20815; phone: (301) 718-4433. FERC Contact: Jim Fargo at [email protected

RESTORING WILD SALMON TO THE PACIFIC NORTHWEST: CHASING AN ILLUSION

EPA Science Inventory

Throughout the Pacific Northwest (northern California, Oregon, Idaho, Washington, and the Columbia Basin portion of British Columbia), many wild salmon "stocks" (a group of interbreeding individuals that is roughly equivalent to a "population") have declined and some have been ...

50 CFR 226.217 - Critical habitat for the Gulf of Maine Distinct Population Segment of Atlantic Salmon (Salmo salar).

Code of Federal Regulations, 2010 CFR

2010-10-01

..., Herseytown Plt, Kingman Twp, Lee, Lincoln, Mattawamkeag, Mount Chase, Patten, Prentiss Twp T7 R3 NBPP..., Hudson, Indian Island, Kenduskeag, Lagrange, Lakeville, Lee, Levant, Lincoln, Lowell, Mattamiscontis Twp...

50 CFR 226.217 - Critical habitat for the Gulf of Maine Distinct Population Segment of Atlantic Salmon (Salmo salar).

Code of Federal Regulations, 2011 CFR

2011-10-01

..., Herseytown Plt, Kingman Twp, Lee, Lincoln, Mattawamkeag, Mount Chase, Patten, Prentiss Twp T7 R3 NBPP..., Hudson, Indian Island, Kenduskeag, Lagrange, Lakeville, Lee, Levant, Lincoln, Lowell, Mattamiscontis Twp...

THE SWIFT BAT SURVEY DETECTS TWO OPTICAL BROAD LINE, X-RAY HEAVILY OBSCURED ACTIVE GALAXIES: NVSS 193013+341047 AND IRAS 05218-1212

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hogg, J. Drew; Winter, Lisa M.; Mushotzky, Richard F.

2012-06-20

The Swift Burst Alert Telescope (BAT) is discovering interesting new objects while monitoring the sky in the 14-195 keV band. Here we present the X-ray properties and spectral energy distributions (SEDs) for two unusual active galactic nucleus sources. Both NVSS 193013+341047 and IRAS 05218-1212 are absorbed, Compton-thin, but heavily obscured (N{sub H} {approx} 10{sup 23} cm{sup -2}), X-ray sources at redshifts <0.1. The SEDs reveal these galaxies to be very red, with high extinction in the optical and UV. A similar SED is seen for the extremely red objects (EROs) detected in the higher redshift universe. This suggests that thesemore » unusual BAT-detected sources are a low-redshift (z << 1) analog to EROs, which recent evidence suggests are a class of the elusive type II quasars. Studying the multi-wavelength properties of these sources may reveal the properties of their high-redshift counterparts.« less

High-z X-ray Obscured Quasars in Galaxies with Extreme Mid-IR/Optical Colors

NASA Astrophysics Data System (ADS)

Piconcelli, E.; Lanzuisi, G.; Fiore, F.; Feruglio, C.; Vignali, C.; Salvato, M.; Grappioni, C.

2009-05-01

Extreme Optical/Mid-IR color cuts have been used to uncover a population of dust-enshrouded, mid-IR luminous galaxies at high redshifts. Several lines of evidence point towards the presence of an heavily absorbed, possibly Compton-thick quasar at the heart of these systems. Nonetheless, the X-ray spectral properties of these intriguing sources still remain largely unexplored. Here we present an X-ray spectroscopic study of a large sample of 44 extreme dust-obscured galaxies (EDOGs) with F24 μm/FR>2000 and F24 μm>1.3 mJy selected from a 6 deg2 region in the SWIRE fields. The application of our selection criteria to a wide area survey has been capable of unveiling a population of X-ray luminous, absorbed z>1 quasars which is mostly missed in the traditional optical/X-ray surveys performed so far. Advances in the understanding of the X-ray properties of these recently-discovered sources by Simbol-X observations will be also discussed.

The space density of Compton-thick AGN at z ≈ 0.8 in the zCOSMOS-Bright Survey

NASA Astrophysics Data System (ADS)

Vignali, C.; Mignoli, M.; Gilli, R.; Comastri, A.; Iwasawa, K.; Zamorani, G.; Mainieri, V.; Bongiorno, A.

2014-11-01

Context. The obscured accretion phase in black hole growth is a crucial ingredient in many models linking the active galactic nuclei (AGN) activity with the evolution of their host galaxy. At present, a complete census of obscured AGN is still missing, although several attempts in this direction have been carried out recently, mostly in the hard X-rays and at mid-infrared wavelengths. Aims: The purpose of this work is to assess whether the [Ne v] emission line at 3426 Å can reliably pick up obscured AGN up to z ≈ 1 by assuming that it is a reliable proxy of the intrinsic AGN luminosity and using moderately deep X-ray data to characterize the amount of obscuration. Methods: A sample of 69 narrow-line (Type 2) AGN at z ≈ 0.65-1.20 were selected from the 20k-zCOSMOS Bright galaxy sample on the basis of the presence of the [Ne v]3426 Å emission. The X-ray properties of these galaxies were then derived using the Chandra-COSMOS coverage of the field; the X-ray-to-[Ne v] flux ratio, coupled with X-ray spectral and stacking analyses, was then used to infer whether Compton-thin or Compton-thick absorption is present in these sources. Then the [Ne v] luminosity function was computed to estimate the space density of Compton-thick AGN at z ≈ 0.8. Results: Twenty-three sources were detected by Chandra, and their properties are consistent with moderate obscuration (on average, ≈a few × 1022 cm-2). The X-ray properties of the remaining 46 X-ray undetected Type 2 AGN (among which we expect to find the most heavily obscured objects) were derived using X-ray stacking analysis. Current data, supported by Monte Carlo simulations, indicate that a fraction as high as ≈40% of the present sample is likely to be Compton thick. The space density of Compton-thick AGN with logL2-10 keV> 43.5 at z = 0.83 is ΦThick = (9.1 ± 2.1) × 10-6 Mpc-3, in good agreement with both X-ray background model expectations and the previously measured space density for objects in a similar redshift and luminosity range. We regard our selection technique for Compton-thick AGN as clean but not complete, since even a mild extinction in the narrow-line region can suppress [Ne v] emission. Therefore, our estimate of their space density should be considered as a lower limit.

Oligosaccharide processing at individual glycosylation sites on MOPC 104E immunoglobulin M. Differences in alpha 1,2-linked mannose processing.

PubMed

Brown, P H; Hickman, S

1986-02-25

Processing of the asparagine-linked oligosaccharides at the known glycosylation sites on the mu-chain of IgM secreted by MOPC 104E murine plasmacytoma cells was investigated. Oligosaccharides present on intracellular mu-chain precursors were of the high mannose type, remaining susceptible to endo-beta-N-acetylglucosaminidase H. However, only 26% of the radioactivity was released from [3H]mannose-labeled secreted IgM glycopeptides, consistent with the presence of high mannose-type and complex-type oligosaccharides on the mature mu-chain. [3H]Mannose-labeled cyanogen bromide glycopeptides derived from mu-chains of secreted IgM were isolated and analyzed to identify the glycopeptide containing the high mannose-type oligosaccharide from those containing complex-type structures. [3H]Mannose-labeled intracellular mu-chain cyanogen bromide glycopeptides corresponding to those from secreted IgM were isolated also, and the time courses of oligosaccharide processing at the individual glycosylation sites were determined. The major oligosaccharides on all intracellular mu-chain glycopeptides after 20 min of pulse labeling with [3H]mannose were identified as Man8GlcNAc2, Man9GlcNAc2, and Glc1Man9GlcNAc2. Processing of the oligosaccharide destined to become the high mannose-type structure on the mature protein was rapid. After 30 min of chase incubation the predominant structures of this oligosaccharide were Man5GlcNAc2 and Man6GlcNAc2 which were also identified on the high mannose-type oligosaccharide of the secreted mu-chain. In contrast, processing of oligosaccharides destined to become complex type was considerably slower. Even after 180 min of chase incubation, Man7GlcNAc2 and Man8GlcNAc2 were the predominant structures at some of these glycosylation sites. The isomeric structures of Man8GlcNAc2 obtained from all of the glycosylation sites were identical. Thus, the different rates of processing were not the result of a different sequence of alpha 1,2-mannose removal.

A Robust Test of the Unified Model for Seyfert Galaxies with Implications for the Starburst Phenomenon

NASA Technical Reports Server (NTRS)

Weaver, Kimberly A.

1997-01-01

My research involves detailed analysis of X-ray emission from Active Galactic Nuclei (AGN). For over a decade, the paradigm for AGN has rested soundly on the unified model hypothesis, which posits that the only difference between broad-line objects (e.g., Type 1 Seyfert galaxies) and narrow-line objects (e.g., Type 2 Seyferts) is that in the former case our line of sight evades toroidal obscuration surrounding the nucleus, while in the latter, our line of sight is blocked by the optically thick torus. It is well established that some Seyfert 2s contain Seyfert I nuclei (i.e., a hidden broad line region), but whether or not all Seyfert 2s contain obscured Seyfert 1 nuclei or whether some Seyfert 2s are intrinsically Seyfert 2s is not known. Optical, IR, and UV surveys are not appropriate to examine this hypothesis because such emissions are either anisotropic or subject to the effects of obscuration, and thus depend strongly on viewing angle. Hard X-rays, on the other hand, can penetrate gas with column densities as high as 10( exp 24.5) cm(-2) and thus provide reliable, direct probes of the cores of heavily obscured AGN. Combining NASA archival data from the Advanced Satellite of Cosmology and Astrophysics (ASCA), the Rossi X-ray Timing Explorer (RXTE), and Rosat, I am accumulating X-ray data between 0.1 and 60 keV to produce a catalog of the broad-band X-ray spectral properties of Seyfert galaxies. These data will be used to perform concrete tests of the unified model, and (compared with similar data on Starbursts) to examine a possible evolutionary connection between Seyfert and Starburst galaxies.

Is there still a role for intraoperative enteroscopy in patients with obscure gastrointestinal bleeding?

PubMed

Monsanto, Pedro; Almeida, Nuno; Lérias, Clotilde; Figueiredo, Pedro; Gouveia, Hermano; Sofia, Carlos

2012-04-01

in 21st century, endoscopic study of the small intestine has undergone a revolution with capsule endoscopy and balloon-assisted enteroscopy. The difficulties and morbidity associated with intraoperative enteroscopy, the gold-standard in the 20th century, made this technique to be relegated to a second level. evaluate the actual role and assess the diagnostic and therapeutic value of intraoperative enteroscopy in patients with obscure gastrointestinal bleeding. we conducted a retrospective study of 19 patients (11 males; mean age: 66.5 ± 15.3 years) submitted to 21 IOE procedures for obscure GI bleeding. Capsule endoscopy and double balloon enteroscopy had been performed in 10 and 5 patients, respectively. with intraoperative enteroscopy a small bowel bleeding lesion was identified in 79% of patients and a gastrointestinal bleeding lesion in 94%. Small bowel findings included: angiodysplasia (n = 6), ulcers (n = 4), small bowel Dieulafoy´s lesion (n = 2), bleeding from anastomotic vessels (n = 1), multiple cavernous hemangiomas (n = 1) and bleeding ectopic jejunal varices (n = 1). Agreement between capsule endoscopy and intraoperative enteroscopy was 70%. Endoscopic and/or surgical treatment was used in 77.8% of the patients with a positive finding on intraoperative enteroscopy, with a rebleeding rate of 21.4% in a mean 21-month follow-up period. Procedure-related mortality and postoperative complications have been 5 and 21%, respectively. intraoperative enteroscopy remains a valuable tool in selected patients with obscure GI bleeding, achieving a high diagnostic yield and allowing an endoscopic and/or surgical treatment in most of them. However, as an invasive procedure with relevant mortality and morbidity, a precise indication for its use is indispensable.

Galaxy and mass assembly (GAMA): dust obscuration in galaxies and their recent star formation histories

NASA Astrophysics Data System (ADS)

Wijesinghe, D. B.; Hopkins, A. M.; Sharp, R.; Gunawardhana, M.; Brough, S.; Sadler, E. M.; Driver, S.; Baldry, I.; Bamford, S.; Liske, J.; Loveday, J.; Norberg, P.; Peacock, J.; Popescu, C. C.; Tuffs, R. J.; Bland-Hawthorn, J.; Cameron, E.; Croom, S.; Frenk, C.; Hill, D.; Jones, D. H.; van Kampen, E.; Kelvin, L.; Kuijken, K.; Madore, B.; Nichol, B.; Parkinson, H.; Pimbblet, K. A.; Prescott, M.; Robotham, A. S. G.; Seibert, M.; Simmat, E.; Sutherland, W.; Taylor, E.; Thomas, D.

2011-02-01

We present self-consistent star formation rates derived through pan-spectral analysis of galaxies drawn from the Galaxy and Mass Assembly (GAMA) survey. We determine the most appropriate form of dust obscuration correction via application of a range of extinction laws drawn from the literature as applied to Hα, [O II] and UV luminosities. These corrections are applied to a sample of 31 508 galaxies from the GAMA survey at z < 0.35. We consider several different obscuration curves, including those of Milky Way, Calzetti and Fischera & Dopita curves and their effects on the observed luminosities. At the core of this technique is the observed Balmer decrement, and we provide a prescription to apply optimal obscuration corrections using the Balmer decrement. We carry out an analysis of the star formation history (SFH) using stellar population synthesis tools to investigate the evolutionary history of our sample of galaxies as well as to understand the effects of variation in the initial mass function (IMF) and the effects this has on the evolutionary history of galaxies. We find that the Fischera & Dopita obscuration curve with an Rv value of 4.5 gives the best agreement between the different SFR indicators. The 2200 Å feature needed to be removed from this curve to obtain complete consistency between all SFR indicators suggesting that this feature may not be common in the average integrated attenuation of galaxy emission. We also find that the UV dust obscuration is strongly dependent on the SFR.

Rise of a Cybered Westphalian Age

DTIC Science & Technology

2011-01-01

a Cybered Westphalian Age Strategic Studies Quarterly ♦ Spring 2011 [ 39 ] their societies, into critical assets of families , banks, townships...women in positions of power and chase P2P porn sites and dissidents internally. The Chinese bureaucracy will refuse to agree to international

Black Newspapers: Neglected Source for the "New South."

ERIC Educational Resources Information Center

Beatty, Bess

1980-01-01

Examines the political climate and popular Black opinion in the late nineteenth century South through the writings of six Black southern newspaper editors (Pinckney Benton Stewart Pinchback, Charles Hendley, W. Calvin Chase, John Mitchell, Jr., William Pledger, and John Willis Menard). (GC)

Fort Douglas, Stilwell Field, The portion of Fort Douglas bounded ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Fort Douglas, Stilwell Field, The portion of Fort Douglas bounded by De Trobriand Street on the north, Fort Douglas Boulevard on the east, Potter Street on the south, and Chase Street on the west. , Salt Lake City, Salt Lake County, UT

Fiscal Year 2007 House Budget Hearing

NASA Image and Video Library

2006-02-16

NASA Administrator Michael Griffin, right, and Brian Chase, NASA's Assistant Administrator for Legislative Affairs confer prior to the start of a hearing before the House Science & Technology Committee regarding NASA's FY 2007 budget request, Thursday, Feb., 16, 2006, in Washington. Photo Credit: (NASA/Bill Ingalls)

75 FR 51849 - Investigations Regarding Certifications of Eligibility To Apply for Worker Adjustment Assistance

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-23

... Kimble Chase Life Science Vineland, NJ 08/04/10 07/14/10 and Research Products, LLC (Company). 74464.../10 74488 Computer Sciences Newark, DE 08/06/10 07/30/10 Corporation (CSC) (State/ One-Stop). 74489...

RESTORING WILD SALMON TO THE PACIFIC NORTHWEST: CHASING AN ILLUSION?

EPA Science Inventory

Throughout the Pacific Northwest (northern California, Oregon, Idaho, Washington, and the Columbia Basin portion of British Columbia), many wild salmon "stocks" (a group of interbreeding individuals that is roughly equivalent to a "population) have declined and some have been e...

Parkinson's disease: diagnostic potential of high-resolution phase difference enhanced MR imaging at 3 T.

PubMed

Kakeda, Shingo; Korogi, Yukunori; Yoneda, Tetsuya; Watanabe, Keita; Moriya, Junji; Murakami, Yu; Sato, Toru; Hiai, Yasuhiro; Ohnari, Norihiro; Ide, Satoru; Okada, Kazumasa; Uozumi, Takenori; Tsuji, Sadatoshi; Hirai, Toshinori; Yamashita, Yasuyuki

2013-04-01

To determine whether it is possible to diagnose patients with Parkinson's disease (PD) on an individual basis using magnetic resonance imaging with phase difference enhanced imaging (PADRE). PADRE delineated the crural fibres as a layer of low signal intensity and the substantia nigra as a layer of medium signal intensity in a healthy volunteer, and showed a clear boundary between the crural fibres and the substantia nigra (BCS). Twenty-four PD patients and 24 control subjects were enrolled. Contrast ratios between the substantia nigra and occipital white matter were calculated, and two radiologists independently reviewed the PADRE findings regarding BCS obscuration. Mean contrast ratio in PD patients was significantly higher than in control subjects (0.56 vs 0.39, P < 0.01). The BCS on PADRE was obscured significantly more frequently in any subgroups with PD patients compared with control subjects (P < 0.01). The observation of BCS obscuration had a sensitivity, specificity and accuracy for the diagnosis of PD of 92 %, 88 % and 90 % for radiologist 1 and 83 %, 88 % and 85 % for radiologist 2, respectively. PADRE is able to identify PD in patients as a loss of delineation between the crural fibres and the substantia nigra on an individual basis.

Reddening and He i{sup ∗} λ 10830 Absorption Lines in Three Narrow-line Seyfert 1 Galaxies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhang, Shaohua; Zhou, Hongyan; Shi, Xiheng

We report the detection of heavy reddening and the He i* λ 10830 absorption lines at the active galactic nucleus (AGN) redshift in three narrow-line Seyfert 1 galaxies: SDSS J091848.61+211717.0, SDSS J111354.66+124439.0, and SDSS J122749.13+321458.9. They exhibit very red optical to near-infrared colors, narrow Balmer/Paschen broad emission lines and He i* λ 10830 absorption lines. The ultraviolet-optical-infrared nucleus continua are reddened by the SMC extinction law of E ( B − V ) ∼ 0.74, 1.17, and 1.24 mag for three objects, which are highly consistent with the values obtained from the broad-line Balmer decrements, but larger than those ofmore » narrow emission lines. The reddening analysis suggests that the extinction dust simultaneously obscures the accretion disk, the broad emission-line region, and the hot dust from the inner edge of the torus. It is possible that the dust obscuring the AGN structures is the dusty torus itself. Furthermore, the Cloudy analysis of the He i* λ 10830 absorption lines proposes the distance of the absorption materials to be the extend scale of the torus, which greatly increases probabilities of the obscure and absorption materials being the dusty torus.« less

DUST PROPERTIES OF LOCAL DUST-OBSCURED GALAXIES WITH THE SUBMILLIMETER ARRAY

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hwang, Ho Seong; Andrews, Sean M.; Geller, Margaret J., E-mail: hhwang@cfa.harvard.edu, E-mail: sandrews@cfa.harvard.edu, E-mail: mgeller@cfa.harvard.edu

We report Submillimeter Array observations of the 880 μm dust continuum emission for four dust-obscured galaxies (DOGs) in the local universe. Two DOGs are clearly detected with S{sub ν}(880 μm) =10-13 mJy and S/N > 5, but the other two are not detected with 3σ upper limits of S{sub ν}(880 μm) =5-9 mJy. Including an additional two local DOGs with submillimeter data from the literature, we determine the dust masses and temperatures for six local DOGs. The infrared luminosities and dust masses for these DOGs are in the ranges of 1.2-4.9 × 10{sup 11}(L{sub ☉}) and 4-14 × 10{sup 7}(M{submore » ☉}), respectively. The dust temperatures derived from a two-component modified blackbody function are 23-26 K and 60-124 K for the cold and warm dust components, respectively. Comparison of local DOGs with other infrared luminous galaxies with submillimeter detections shows that the dust temperatures and masses do not differ significantly among these objects. Thus, as argued previously, local DOGs are not a distinctive population among dusty galaxies, but simply represent the high-end tail of the dust obscuration distribution.« less

Four-wavelength lidar evaluation of particle characteristics and aerosol densities

NASA Astrophysics Data System (ADS)

Uthe, E. E.; Livingston, J. M.; Delateur, S. A.; Nielsen, N. B.

1985-06-01

The SRI International four-wavelength (0.53, 1.06, 3.8, 10.6 micron) lidar systems was used during the SNOW-ONE-B and Smoke Week XI/SNOW-TWO field experiments to validate its capabilities in assessing obscurant optical and physical properties. The lidar viewed along a horizontal path terminated by a passive reflector. Data examples were analyzed in terms of time-dependent transmission, wavelength dependence of optical depth, and range-resolved extinction coefficients. Three methods were used to derive extinction data from the lidar signatures. These were target method, Klett method and experimental data method. The results of the field and analysis programs are reported in the journal and conference papers that are appended to this report, and include: comparison study of lidar extinction methods, submitted to applied optics, error analysis of lidar solution techniques for range-resolved extinction coefficients based on observational data, smoke/obscurants symposium 9, Four--Wavelength Lidar Measurements from smoke week 6/SNOW-TWO, smoke/obscurants symposium 8, SNOW-ONE-B multiple-wavelength lidar measurements. Snow symposium 3, and lidar applications for obscurant evaluations, smoke/obscurants Symposium 7. The report also provides a summary of background work leading to this project, and of project results.

Optical Surface Analysis Code (OSAC). 7.0

NASA Technical Reports Server (NTRS)

Glenn, P.

1998-01-01

The purpose of this modification to the Optical Surface Analysis Code (OSAC) is to upgrade the PSF program to allow the user to get proper diffracted energy normalization even when deliberately obscuring rays with internal obscurations.

38. INTERIOR VIEW OF TANK. Suspended wooden platform obscures bottom ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

38. INTERIOR VIEW OF TANK. Suspended wooden platform obscures bottom of tank No date - U.S. Naval Submarine Base, New London Submarine Escape Training Tank, Albacore & Darter Roads, Groton, New London County, CT

Cut at eastern approach, with portal obscured by train entering ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Cut at eastern approach, with portal obscured by train entering tunnel, looking NNW. - Philadelphia & Reading Railroad, Black Rock Tunnel, Beneath Black Rock Hill, southwest of Black Rock Dam, Phoenixville, Chester County, PA

Alpha-SNAP functions in insulin exocytosis from mature, but not immature secretory granules in pancreatic beta cells.

PubMed

Nakamichi, Y; Nagamatsu, S

1999-06-24

To explore alpha-SNAP function in insulin exocytosis from either immature or mature secretory granules in pancreatic beta cells, we studied the effects of overexpression of adenovirus-mediated wild-type alpha-SNAP and C-terminally deleted alpha-SNAP mutant (1-285) on newly synthesized proinsulin and insulin release by rat islets and MIN6 cells. Rat islets overexpressing alpha-SNAP and mutant alpha-SNAP were pulse-chased. Exocytosis from immature and mature insulin secretory granules was measured as fractional (%) labeled-proinsulin release immediately after the pulse-labeling and percentage labeled-insulin release after a 3-h chase period, respectively. There was no difference in percentage labeled-proinsulin release between the control and alpha-SNAP or mutant alpha-SNAP-overexpressed islets. Although percentage labeled-insulin release after a 3-h chase period was significantly increased in alpha-SNAP-overexpressed islets, it was decreased in mutant alpha-SNAP-overexpressed islets. Thus, the results demonstrated that alpha-SNAP overexpression in rat islets primarily increased exocytosis from mature, but not immature insulin secretory granules. On the other hand, in MIN6 cells, alpha-SNAP overexpression scarcely affected glucose-stimulated insulin release; therefore, we examined the effect of mutant alpha-SNAP overexpression as the dominant-negative inhibitor on the newly synthesized proinsulin/insulin release using the same protocol as in the rat islet experiments. alpha-SNAP mutant (1-285) overexpression in MIN6 cells decreased the percentage labeled insulin release from mature secretory granules, but not percentage labeled proinsulin release from immature secretory granules. Thus, our data demonstrate that alpha-SNAP functions mainly in the mature insulin secretory granules in pancreatic beta cells. Copyright 1999 Academic Press.

Long-Term Exposure to Primary Traffic Pollutants and Lung Function in Children: Cross-Sectional Study and Meta-Analysis.

PubMed

Barone-Adesi, Francesco; Dent, Jennifer E; Dajnak, David; Beevers, Sean; Anderson, H Ross; Kelly, Frank J; Cook, Derek G; Whincup, Peter H

2015-01-01

There is widespread concern about the possible health effects of traffic-related air pollution. Nitrogen dioxide (NO2) is a convenient marker of primary pollution. We investigated the associations between lung function and current residential exposure to a range of air pollutants (particularly NO2, NO, NOx and particulate matter) in London children. Moreover, we placed the results for NO2 in context with a meta-analysis of published estimates of the association. Associations between primary traffic pollutants and lung function were investigated in 4884 children aged 9-10 years who participated in the Child Heart and Health Study in England (CHASE). A systematic literature search identified 13 studies eligible for inclusion in a meta-analysis. We combined results from the meta-analysis with the distribution of the values of FEV1 in CHASE to estimate the prevalence of children with abnormal lung function (FEV1<80% of predicted value) expected under different scenarios of NO2 exposure. In CHASE, there were non-significant inverse associations between all pollutants except ozone and both FEV1 and FVC. In the meta-analysis, a 10 μg/m3 increase in NO2 was associated with an 8 ml lower FEV1 (95% CI: -14 to -1 ml; p: 0.016). The observed effect was not modified by a reported asthma diagnosis. On the basis of these results, a 10 μg/m3 increase in NO2 level would translate into a 7% (95% CI: 4% to 12%) increase of the prevalence of children with abnormal lung function. Exposure to traffic pollution may cause a small overall reduction in lung function and increase the prevalence of children with clinically relevant declines in lung function.

Variability in size-selective mortality obscures the importance of larval traits to recruitment success in a temperate marine fish.

PubMed

Murphy, Hannah M; Warren-Myers, Fletcher W; Jenkins, Gregory P; Hamer, Paul A; Swearer, Stephen E

2014-08-01

In fishes, the growth-mortality hypothesis has received broad acceptance as a driver of recruitment variability. Recruitment is likely to be lower in years when the risk of starvation and predation in the larval stage is greater, leading to higher mortality. Juvenile snapper, Pagrus auratus (Sparidae), experience high recruitment variation in Port Phillip Bay, Australia. Using a 5-year (2005, 2007, 2008, 2010, 2011) data set of larval and juvenile snapper abundances and their daily growth histories, based on otolith microstructure, we found selective mortality acted on larval size at 5 days post-hatch in 4 low and average recruitment years. The highest recruitment year (2005) was characterised by no size-selective mortality. Larval growth of the initial larval population was related to recruitment, but larval growth of the juveniles was not. Selective mortality may have obscured the relationship between larval traits of the juveniles and recruitment as fast-growing and large larvae preferentially survived in lower recruitment years and fast growth was ubiquitous in high recruitment years. An index of daily mortality within and among 3 years (2007, 2008, 2010), where zooplankton were concurrently sampled with ichthyoplankton, was related to per capita availability of preferred larval prey, providing support for the match-mismatch hypothesis. In 2010, periods of low daily mortality resulted in no selective mortality. Thus both intra- and inter-annual variability in the magnitude and occurrence of selective mortality in species with complex life cycles can obscure relationships between larval traits and population replenishment, leading to underestimation of their importance in recruitment studies.

Four hot DOGs in the microwave

NASA Astrophysics Data System (ADS)

Frey, Sándor; Paragi, Zsolt; Gabányi, Krisztina Éva; An, Tao

2016-01-01

Hot dust-obscured galaxies (hot DOGs) are a rare class of hyperluminous infrared galaxies identified with the Wide-field Infrared Survey Explorer (WISE) satellite. The majority of them are at high redshifts (z ˜ 2-3), at the peak epoch of star formation in the Universe. Infrared, optical, radio, and X-ray data suggest that hot DOGs contain heavily obscured, extremely luminous active galactic nuclei (AGN). This class may represent a short phase in the life of the galaxies, signifying the transition from starburst- to AGN-dominated phases. Hot DOGs are typically radio-quiet, but some of them show mJy-level emission in the radio (microwave) band. We observed four hot DOGs using the technique of very long baseline interferometry (VLBI). The 1.7 GHz observations with the European VLBI Network (EVN) revealed weak radio features in all sources. The radio is free from dust obscuration and, at such high redshifts, VLBI is sensitive only to compact structures that are characteristic of AGN activity. In two cases (WISE J0757+5113, WISE J1603+2745), the flux density of the VLBI-detected components is much smaller than the total flux density, suggesting that ˜70-90 per cent of the radio emission, while still dominated by AGN, originates from angular scales larger than that probed by the EVN. The source WISE J1146+4129 appears a candidate compact symmetric object, and WISE J1814+3412 shows a 5.1 kpc double structure, reminiscent of hotspots in a medium-sized symmetric object. Our observations support that AGN residing in hot DOGs may be genuine young radio sources where starburst and AGN activities coexist.

The power of infrared AGN selection in mergers: a theoretical study

NASA Astrophysics Data System (ADS)

Blecha, Laura; Snyder, Gregory F.; Satyapal, Shobita; Ellison, Sara L.

2018-05-01

The role of galaxy mergers in fueling active galactic nuclei (AGN) is still debated, owing partly to selection effects inherent to studies of the merger/AGN connection. In particular, luminous AGN are often obscured in late-stage mergers. Mid-infrared (IR) color selection of dust-enshrouded AGN with, e.g., the Wide-field Infrared Survey Explorer (WISE) has uncovered large new populations of obscured AGN. However, this method is sensitive mainly to AGN that dominate emission from the host. To understand how selection biases affect mid-IR studies of the merger/AGN connection, we simulate the evolution of AGN throughout galaxy mergers. Although mid-IR colors closely trace luminous, obscured AGN, we show that nearly half of merger-triggered AGN are missed with common mid-IR selection criteria, even in late-stage, gas-rich major mergers. At z ⪉ 0.5, where merger signatures and dual nuclei can most easily be detected, we find that a more lenient W1 - W2 >0.5 cut greatly improves completeness without significantly decreasing reliability. Extreme nuclear starbursts are briefly able to mimic this AGN signature, but this is largely irrelevant in mergers, where such starbursts are accompanied by AGN. We propose a two-color cut that yields high completeness and reliability even in starbursting systems. Further, we show that mid-IR color selection very effectively identifies dual AGN hosts, with the highest fraction at the smallest separations (<3 kpc). Thus, many merger hosts of mid-IR AGN should contain unresolved dual AGN; these are ideal targets for high-resolution follow-up, particularly with the James Webb Space Telescope.

NGC 5506 unmasked as a Narrow Line Seyfert 1:. A direct view of the broad line region using near-IR spectroscopy

NASA Astrophysics Data System (ADS)

Nagar, N. M.; Oliva, E.; Marconi, A.; Maiolino, R.

2002-08-01

This letter presents incontrovertible evidence that NGC 5506 is a Narrow Line Seyfert 1 (NLSy1). Our new 0.9-1.4 mu m spectrum of its nucleus clearly shows the permitted O I lambda 1.1287 mu m line (with full width at half maximum <2000 km s-1) and the ``1 micron Fe II lines''. These lines can only originate in the optically-thick broad line region (BLR) and, among Seyfert nuclei the latter series of lines are seen only in NLSy1s. The obscuration to the BLR, derived from a rough estimate of the O I lambda 1.1287 mu m/O I lambda 8446 ratio and from the reddening of the near-IR Paschen lines, is AV > 5. Together, these results make NGC 5506 the first identified case of an optically-obscured NLSy1. This new classification helps explain its radio to X-ray properties, which until now were considered highly anomalous. However, interesting new concerns are raised: e.g., NGC 5506 is unusual in hosting both a ``type 1'' AGN and a nuclear water vapor megamaser. As the brightest known NLSy1, NGC 5506 is highly suitable for study at wavebands less affected by obscuration. Based on observations made with the Italian Telescopio Nazionale Galileo (TNG) operated on the island of La Palma by the Centro Galileo Galilei of the INAF (Istituto Nazionale di Astrofisica) at the Spanish Observatorio del Roque de los Muchachos of the Instituto de Astrofisica de Canarias.

SR-71B - in Flight with F-18 Chase Aircraft - View from Air Force Tanker

NASA Technical Reports Server (NTRS)

1996-01-01

NASA 831, an SR-71B operated by the Dryden Flight Research Center, Edwards, California, cruises over the Mojave Desert with an F/A-18 Hornet flying safety chase. They were photographed on a 1996 mission from an Air Force refueling tanker The F/A-18 Hornet is used primarily as a safety chase and support aircraft at Dryden. As support aircraft, the F-18s are used for safety chase, pilot proficiency and aerial photography. Two SR-71 aircraft have been used by NASA as testbeds for high-speed and high-altitude aeronautical research. The aircraft, an SR-71A and an SR-71B pilot trainer aircraft, have been based here at NASA's Dryden Flight Research Center, Edwards, California. They were transferred to NASA after the U.S. Air Force program was cancelled. As research platforms, the aircraft can cruise at Mach 3 for more than one hour. For thermal experiments, this can produce heat soak temperatures of over 600 degrees Fahrenheit (F). This operating environment makes these aircraft excellent platforms to carry out research and experiments in a variety of areas -- aerodynamics, propulsion, structures, thermal protection materials, high-speed and high-temperature instrumentation, atmospheric studies, and sonic boom characterization. The SR-71 was used in a program to study ways of reducing sonic booms or over pressures that are heard on the ground, much like sharp thunderclaps, when an aircraft exceeds the speed of sound. Data from this Sonic Boom Mitigation Study could eventually lead to aircraft designs that would reduce the 'peak' overpressures of sonic booms and minimize the startling affect they produce on the ground. One of the first major experiments to be flown in the NASA SR-71 program was a laser air data collection system. It used laser light instead of air pressure to produce airspeed and attitude reference data, such as angle of attack and sideslip, which are normally obtained with small tubes and vanes extending into the airstream. One of Dryden's SR-71s was used for the Linear Aerospike Rocket Engine, or LASRE Experiment. Another earlier project consisted of a series of flights using the SR-71 as a science camera platform for NASA's Jet Propulsion Laboratory in Pasadena, California. An upward-looking ultraviolet video camera placed in the SR-71's nosebay studied a variety of celestial objects in wavelengths that are blocked to ground-based astronomers. Earlier in its history, Dryden had a decade of past experience at sustained speeds above Mach 3. Two YF-12A aircraft and an SR-71 designated as a YF-12C were flown at the center between December 1969 and November 1979 in a joint NASA/USAF program to learn more about the capabilities and limitations of high-speed, high-altitude flight. The YF-12As were prototypes of a planned interceptor aircraft based on a design that later evolved into the SR-71 reconnaissance aircraft. Dave Lux was the NASA SR-71 project manger for much of the decade of the 1990s, followed by Steve Schmidt. Developed for the USAF as reconnaissance aircraft more than 30 years ago, SR-71s are still the world's fastest and highest-flying production aircraft. The aircraft can fly at speeds of more than 2,200 miles per hour (Mach 3+, or more than three times the speed of sound) and at altitudes of over 85,000 feet. The Lockheed Skunk Works (now Lockheed Martin) built the original SR-71 aircraft. Each aircraft is 107.4 feet long, has a wingspan of 55.6 feet, and is 18.5 feet high (from the ground to the top of the rudders, when parked). Gross takeoff weight is about 140,000 pounds, including a possible fuel weight of 80,280 pounds. The airframes are built almost entirely of titanium and titanium alloys to withstand heat generated by sustained Mach 3 flight. Aerodynamic control surfaces consist of all-moving vertical tail surfaces, ailerons on the outer wings, and elevators on the trailing edges between the engine exhaust nozzles. The two SR-71s at Dryden have been assigned the following NASA tail numbers: NASA 844 (A model), military serial 61-7980 and NASA 831 (B model), military serial 61-7956. From 1990 through 1994, Dryden also had another 'A' model, NASA 832, military serial 61-7971. This aircraft was returned to the USAF inventory and was the first aircraft reactivated for USAF reconnaissance purposes in 1995. It has since returned to Dryden along with SR-71A 61-7967.

The distant red galaxy neighbour population of 1

NASA Astrophysics Data System (ADS)

Bornancini, C.; García Lambas, D.

We study the Distant Red Galaxy (DRG, J-Ks > 2.3) neighbour population of Quasi Stellar Objects (QSOs) selected from the Sloan Digital Sky Survey (SDSS) in the redshift range 1 < z < 2. We perform a similar analysis for optically obscured AGNs (i.e. with a limiting magnitude I > 24) detected in the mid-infrared (24 microns) with the Spitzer Space Telescope and a mean redshift z~2.2 in the Flamingos Extragalactic Survey (FLAMEX). We present results on the cross-correlation function of DRGs around QSOs and optically faint mid-infrared sources. The corresponding correlation length obtained for the QSO sample targets is r_0=5.4+/-1.6 Mpc. For the optically obscured galaxy sample we find r_0=8.9+/-1.4 Mpc. These results indicate that optically faint obscured sources are located in denser environment of evolved red galaxies compare to QSOs.

Scientific Laws, Principles and Theories: A Reference Guide by Robert E. Krebs

NASA Astrophysics Data System (ADS)

Bernal, Pedro

2001-08-01

My having made a number of negative observations, particularly about the introduction, should not obscure the fact that the entries will be useful to high school and college science students and that this book will be a good addition to science collections in libraries.

Lincoln Laboratory demonstrates highly accurate vehicle localization under adverse weather conditions

DTIC Science & Technology

2016-05-25

2016 Lincoln Laboratory demonstrates highly accurate vehicle localization under adverse weather conditions A ground-penetrating radar system...the problems limiting the development and adoption of self-driving vehicles: how can a vehicle navigate to stay within its lane when bad weather ... weather conditions, but it is challenging, even impossible, for them to work when snow covers the markings and surfaces or precipitation obscures points

Stressors and Turning Points in High School and Dropout: A Stress Process, Life Course Framework

ERIC Educational Resources Information Center

Dupéré, Véronique; Leventhal, Tama; Dion, Eric; Crosnoe, Robert; Archambault, Isabelle; Janosz, Michel

2015-01-01

High school dropout is commonly seen as the result of a long-term process of failure and disengagement. As useful as it is, this view has obscured the heterogeneity of pathways leading to dropout. Research suggests, for instance, that some students leave school not as a result of protracted difficulties but in response to situations that emerge…

Eliminate the "Bounce"!

ERIC Educational Resources Information Center

Leigh, Susan

2016-01-01

The "bounce" (coined by students at Susan Leigh's last campus) refers to the amount of time students spent chasing signatures and removing often-unnecessary registration "holds" in order to attend their classes. Leigh explains that all this chaos from complex, separately housed transactional business processes has led to the…

1. Overview of Independence Street, with Building 1001 (administration building) ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

1. Overview of Independence Street, with Building 1001 (administration building) on right, looking south - Naval Air Station Chase Field, Texas State Highway 202, 4.8 miles east of intersection of Texas State Highway 202 & U.S. State Highway 181, Beeville, Bee County, TX

Conway Morris: Extraterrestrials: Aliens like us?

NASA Astrophysics Data System (ADS)

Morris, Simon Conway

2005-08-01

So what are they going to be like, those long-expected extraterrestrials? Hideous hydrocarbon arachnoids, waving laser cannons as they chase screaming humans, repulsively surveying the scene through empathy-free compound eyes? Or maybe laughing bipeds, chatting away, holding a glass of wine, a bit like us?

75 FR 51832 - Kansas; Major Disaster and Related Determinations

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-23

... determinations. DATES: Effective Date: August 10, 2010. FOR FURTHER INFORMATION CONTACT: Peggy Miller, Recovery... Hazard Mitigation will be limited to 75 percent of the total eligible costs. Further, you are authorized... Atchison, Brown, Butler, Chase, Clay, Cloud, Comanche, Doniphan, Ellis, Franklin, Greenwood, Harvey, Jewell...

Biological Collections: Chasing the Ideal

PubMed Central

Kamenski, P. A.; Sazonov, A. E.; Fedyanin, A. A.; Sadovnichy, V. A.

2016-01-01

This article is based on the results of an analysis of existing biological collections in Russia and abroad set up in the framework of the project “Scientific Basis of the National Biobank –Depository of Living Systems” by M.V. Lomonosov Moscow State University [1]. PMID:27437135

17. INTERIOR VIEW INSIDE BUNKER. MAN SEATED AT LEFT LOOKS ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

17. INTERIOR VIEW INSIDE BUNKER. MAN SEATED AT LEFT LOOKS AT OPENING TO CABLE CHASE, HIS HANDS ON MANUALLY-OPERATED PULLEY. INEL PHOTO NUMBER 65-6179, TAKEN NOVEMBER 10, 1965. - Idaho National Engineering Laboratory, Advanced Reentry Vehicle Fusing System, Scoville, Butte County, ID

Chasing a Fault across Ship and Shore

ERIC Educational Resources Information Center

Evans, Michael A.; Schwen, Thomas M.

2006-01-01

Knowledge management (KM) in the U.S. Navy is championed as a strategic initiative to improve shipboard maintenance and troubleshooting at a distance. The approach requires capturing, coordinating, and distributing domain expertise in electronics and computer engineering via advanced information and communication technologies. Coordination must be…

3. VIEW OF ARVFS BUNKER TAKEN FROM APPROXIMATELY 150 FEET ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

3. VIEW OF ARVFS BUNKER TAKEN FROM APPROXIMATELY 150 FEET EAST OF BUNKER DOOR. CAMERA FACING WEST. VIEW SHOWS EARTH MOUND COVERING CONTROL BUNKER AND REMAINS OF CABLE CHASE. - Idaho National Engineering Laboratory, Advanced Reentry Vehicle Fusing System, Scoville, Butte County, ID

Infants' Perception of Chasing

ERIC Educational Resources Information Center

Frankenhuis, Willem E.; House, Bailey; Barrett, H. Clark; Johnson, Scott P.

2013-01-01

Two significant questions in cognitive and developmental science are first, whether objects and events are selected for attention based on their features (featural processing) or the configuration of their features (configural processing), and second, how these modes of processing develop. These questions have been addressed in part with…

Dramatic Improvements in Beach Water Quality Following Gull Removal

EPA Science Inventory

Gulls are often cited as important contributors of fecal contamination to surface waters, and some recreational beaches have used gull control measures to improve microbial water quality. In this study, gulls were chased from a Lake Michigan beach using specially trained dogs, a...

NASA 947 and NASA 904 during training flight over White Sands, New Mexico

NASA Technical Reports Server (NTRS)

1982-01-01

NASA 947 and NASA 904 during a training and familiarization flight over White Sands, New Mexico. The Gulfstream aircraft on the left is NASA's Space Shuttle Training aircraft (STA) and the T-38 jet serves as a chase plane.

Lockheed L-1011 TriStar to support Adaptive Performance Optimization study with NASA F-18 chase plan

NASA Technical Reports Server (NTRS)

1995-01-01

This Lockheed L-1011 Tristar, seen here June 1995, is currently the subject of a new flight research experiment developed by NASA's Dryden Flight Research Center, Edwards, California, to improve the effiecency of large transport aircraft. Shown with a NASA F-18 chase plane over California's Sierra Nevada mountains during an earlier baseline flight, the jetliner operated by Oribtal Sciences Corp., recently flew its first data-gathering mission in the Adaptive Performance Optimization project. The experiment seeks to reduce fuel comsumption of large jetliners by improving the aerodynamic efficiency of their wings at cruise conditions. A research computer employing a sophisticated software program adapts to changing flight conditions by commanding small movements of the L-1011's outboard ailerons to give its wings the most efficient - or optimal - airfoil. Up to a dozen research flights will be flown in the current and follow-on phases of the project over the next couple years.

NASA's Global Hawk

NASA Image and Video Library

2014-09-23

View from a Chase Plane; HS3 Science Flight 8 Wraps Up The chase plane accompanying NASA's Global Hawk No. 872 captured this picture on Sept. 19 after the Global Hawk completed science flight #8 where it gathered data from a weakening Tropical Storm Edouard over the North Atlantic Ocean. Credit: NASA -- The Hurricane and Severe Storm Sentinel (HS3) is a five-year mission specifically targeted to investigate the processes that underlie hurricane formation and intensity change in the Atlantic Ocean basin. HS3 is motivated by hypotheses related to the relative roles of the large-scale environment and storm-scale internal processes. Read more: espo.nasa.gov/missions/hs3/mission-gallery NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

Development of an autonomous video rendezvous and docking system, phase 2

NASA Technical Reports Server (NTRS)

Tietz, J. C.; Richardson, T. E.

1983-01-01

The critical elements of an autonomous video rendezvous and docking system were built and used successfully in a physical laboratory simulation. The laboratory system demonstrated that a small, inexpensive electronic package and a flight computer of modest size can analyze television images to derive guidance information for spacecraft. In the ultimate application, the system would use a docking aid consisting of three flashing lights mounted on a passive target spacecraft. Television imagery of the docking aid would be processed aboard an active chase vehicle to derive relative positions and attitudes of the two spacecraft. The demonstration system used scale models of the target spacecraft with working docking aids. A television camera mounted on a 6 degree of freedom (DOF) simulator provided imagery of the target to simulate observations from the chase vehicle. A hardware video processor extracted statistics from the imagery, from which a computer quickly computed position and attitude. Computer software known as a Kalman filter derived velocity information from position measurements.

X-15 #3 and F-104A chase plane landing

NASA Technical Reports Server (NTRS)

1960-01-01

Followed by a Lockheed F-104A Starfighter chase plane, the North American X-15 ship #3 (56-6672) sinks toward touchdown on Rogers Dry Lake following a research flight. In the foreground is green smoke, used to indicate wind direction. The F-104 chase pilot joined up with the X-15 as it glided to the landing. The chase pilot was there to warn the X-15 pilot of any problems and to call out the altitude above the lakebed. F-104 aircraft were also used for X-15 pilot training to simulate the landing characteristics of the rocket-powered airplane, which landed without engine power since the rocket engine had already burned all of its propellant before the landing. The F-104s could simulate the steep descent of the X-15 as it glided to a landing. They did this by extending the landing gear and speed brakes while setting the throttle to idle. The X-15 was a rocket-powered aircraft. The original three aircraft were about 50 ft long with a wingspan of 22 ft. The modified #2 aircraft (X-15A-2 was longer.) They were a missile-shaped vehicles with unusual wedge-shaped vertical tails, thin stubby wings, and unique side fairings that extended along the side of the fuselage. The X-15 weighed about 14,000 lb empty and approximately 34,000 lb at launch. The XLR-99 rocket engine, manufactured by Thiokol Chemical Corp., was pilot controlled and was rated at 57,000 lb of thrust, although there are indications that it actually achieved up to 60,000 lb. North American Aviation built three X-15 aircraft for the program. The X-15 research aircraft was developed to provide in-flight information and data on aerodynamics, structures, flight controls, and the physiological aspects of high-speed, high-altitude flight. A follow-on program used the aircraft as testbeds to carry various scientific experiments beyond the Earth's atmosphere on a repeated basis. For flight in the dense air of the usable atmosphere, the X-15 used conventional aerodynamic controls such as rudder surfaces on the vertical stabilizers to control yaw and movable horizontal stabilizers to control pitch when moving in synchronization or roll when moved differentially. For flight in the thin air outside of the appreciable Earth's atmosphere, the X-15 used a reaction control system. Hydrogen peroxide thrust rockets located on the nose of the aircraft provided pitch and yaw control. Those on the wings provided roll control. Because of the large fuel consumption, the X-15 was air launched from a B-52 aircraft at approximately 45,000 ft and a speed of about 500 mph. Depending on the mission, the rocket engine provided thrust for the first 80 to 120 sec of flight. The remainder of the normal 10 to 11 min. flight was powerless and ended with a 200-mph glide landing. Generally, one of two types of X-15 flight profiles was used; a high-altitude flight plan that called for the pilot to maintain a steep rate of climb, or a speed profile that called for the pilot to push over and maintain a level altitude. The X-15 was flown over a period of nearly 10 years -- June 1959 to Oct. 1968 -- and set the world's unofficial speed and altitude records of 4,520 mph (Mach 6.7) and 354,200 ft in a program to investigate all aspects of manned hypersonic flight. Information gained from the highly successful X-15 program contributed to the development of the Mercury, Gemini, and Apollo manned spaceflight programs, and also the Space Shuttle program. The X-15s made a total of 199 flights, and were manufactured by North American Aviation. X-15-1, serial number 56-6670, is now located at the National Air and Space Museum, Washington DC. North American X-15A-2, serial number 56-6671, is at the United States Air Force Museum, Wright-Patterson AFB, Ohio. X-15-3, serial number 56-6672, crashed on 15 November 1967, resulting in the death of Maj. Michael J. Adams.

The Halo Occupation Distribution of obscured quasars: revisiting the unification model

NASA Astrophysics Data System (ADS)

Mitra, Kaustav; Chatterjee, Suchetana; DiPompeo, Michael A.; Myers, Adam D.; Zheng, Zheng

2018-06-01

We model the projected angular two-point correlation function (2PCF) of obscured and unobscured quasars selected using the Wide-field Infrared Survey Explorer (WISE), at a median redshift of z ˜ 1 using a five parameter Halo Occupation Distribution (HOD) parametrization, derived from a cosmological hydrodynamic simulation by Chatterjee et al. The HOD parametrization was previously used to model the 2PCF of optically selected quasars and X-ray bright active galactic nuclei (AGNs) at z ˜ 1. The current work shows that a single HOD parametrization can be used to model the population of different kinds of AGN in dark matter haloes suggesting the universality of the relationship between AGN and their host dark matter haloes. Our results show that the median halo mass of central quasar hosts increases from optically selected (4.1^{+0.3}_{-0.4} × 10^{12} h^{-1} M_{⊙}) and infra-red (IR) bright unobscured populations (6.3^{+6.2}_{-2.3} × 10^{12} h^{-1} M_{⊙}) to obscured quasars (10.0^{+2.6}_{-3.7} × 10^{12} h^{-1} M_{⊙}), signifying an increase in the degree of clustering. The projected satellite fractions also increase from optically bright to obscured quasars and tend to disfavour a simple `orientation only' theory of active galactic nuclei unification. Our results also show that future measurements of the small-scale clustering of obscured quasars can constrain current theories of galaxy evolution where quasars evolve from an IR-bright obscured phase to the optically bright unobscured phase.

The close environments of accreting massive black holes are shaped by radiative feedback.

PubMed

Ricci, Claudio; Trakhtenbrot, Benny; Koss, Michael J; Ueda, Yoshihiro; Schawinski, Kevin; Oh, Kyuseok; Lamperti, Isabella; Mushotzky, Richard; Treister, Ezequiel; Ho, Luis C; Weigel, Anna; Bauer, Franz E; Paltani, Stephane; Fabian, Andrew C; Xie, Yanxia; Gehrels, Neil

2017-09-27

The majority of the accreting supermassive black holes in the Universe are obscured by large columns of gas and dust. The location and evolution of this obscuring material have been the subject of intense research in the past decades, and are still debated. A decrease in the covering factor of the circumnuclear material with increasing accretion rates has been found by studies across the electromagnetic spectrum. The origin of this trend may be driven by the increase in the inner radius of the obscuring material with incident luminosity, which arises from the sublimation of dust; by the gravitational potential of the black hole; by radiative feedback; or by the interplay between outflows and inflows. However, the lack of a large, unbiased and complete sample of accreting black holes, with reliable information on gas column density, luminosity and mass, has left the main physical mechanism that regulates obscuration unclear. Here we report a systematic multi-wavelength survey of hard-X-ray-selected black holes that reveals that radiative feedback on dusty gas is the main physical mechanism that regulates the distribution of the circumnuclear material. Our results imply that the bulk of the obscuring dust and gas is located within a few to tens of parsecs of the accreting supermassive black hole (within the sphere of influence of the black hole), and that it can be swept away even at low radiative output rates. The main physical driver of the differences between obscured and unobscured accreting black holes is therefore their mass-normalized accretion rate.

The close environments of accreting massive black holes are shaped by radiative feedback

NASA Astrophysics Data System (ADS)

Ricci, Claudio; Trakhtenbrot, Benny; Koss, Michael J.; Ueda, Yoshihiro; Schawinski, Kevin; Oh, Kyuseok; Lamperti, Isabella; Mushotzky, Richard; Treister, Ezequiel; Ho, Luis C.; Weigel, Anna; Bauer, Franz E.; Paltani, Stephane; Fabian, Andrew C.; Xie, Yanxia; Gehrels, Neil

2017-09-01

The majority of the accreting supermassive black holes in the Universe are obscured by large columns of gas and dust. The location and evolution of this obscuring material have been the subject of intense research in the past decades, and are still debated. A decrease in the covering factor of the circumnuclear material with increasing accretion rates has been found by studies across the electromagnetic spectrum. The origin of this trend may be driven by the increase in the inner radius of the obscuring material with incident luminosity, which arises from the sublimation of dust; by the gravitational potential of the black hole; by radiative feedback; or by the interplay between outflows and inflows. However, the lack of a large, unbiased and complete sample of accreting black holes, with reliable information on gas column density, luminosity and mass, has left the main physical mechanism that regulates obscuration unclear. Here we report a systematic multi-wavelength survey of hard-X-ray-selected black holes that reveals that radiative feedback on dusty gas is the main physical mechanism that regulates the distribution of the circumnuclear material. Our results imply that the bulk of the obscuring dust and gas is located within a few to tens of parsecs of the accreting supermassive black hole (within the sphere of influence of the black hole), and that it can be swept away even at low radiative output rates. The main physical driver of the differences between obscured and unobscured accreting black holes is therefore their mass-normalized accretion rate.

Readability of self-illuminated signs in a smoke-obscured environment.

DOT National Transportation Integrated Search

1979-11-01

This study investigates the ability of people with normal distant visual acuity to identify self-illuminated emergency signs in a smoke-obscured environment. The results indicate that signs whose background luminance meets or exceeds the requirements...

Landing - STS-2 - Edwards AFB (EAFB), CA

NASA Image and Video Library

1981-11-16

S81-39563 (14 Nov. 1981) --- This view of the space shuttle Columbia (STS-2) was made with a hand-held 70mm camera in the rear station of the T-38 chase plane. Mission specialist/astronaut Kathryn D. Sullivan exposed the frame as astronauts Joe N. Engle and Richard H. Truly aboard the Columbia guided the vehicle to an unpowered but smooth landing on the desert area of Edwards Air Force base in California. The view provides a good study of the high temperature protection material on the underside of the spacecraft which is exposed to the friction on the atmospheric entry on the return to Earth. Also note trails from the wing tips. Photo credit: NASA

Chasing a Comet with a Solar Sail

NASA Technical Reports Server (NTRS)

Stough, Robert W.; Heaton, Andrew F.; Whorton, Mark S.

2008-01-01

Solar sail propulsion systems enable a wide range of missions that require constant thrust or high delta-V over long mission times. One particularly challenging mission type is a comet rendezvous mission. This paper presents optimal low-thrust trajectory designs for a range of sailcraft performance metrics and mission transit times that enables a comet rendezvous mission. These optimal trajectory results provide a trade space which can be parameterized in terms of mission duration and sailcraft performance parameters such that a design space for a small satellite comet chaser mission is identified. These results show that a feasible space exists for a small satellite to perform a comet chaser mission in a reasonable mission time.

The Priming of Amylose Synthesis in Arabidopsis Leaves1

PubMed Central

Zeeman, Samuel C.; Smith, Steven M.; Smith, Alison M.

2002-01-01

We investigated the mechanism of amylose synthesis in Arabidopsis leaves using 14C-labeling techniques. First, we tested the hypothesis that short malto-oligosaccharides (MOS) may act as primers for granule-bound starch synthase I. We found increased amylose synthesis in isolated starch granules supplied with ADP[14C]glucose (ADP[14C]Glc) and MOS compared with granules supplied with ADP[14C]Glc but no MOS. Furthermore, using a MOS-accumulating mutant (dpe1), we found that more amylose was synthesized than in the wild type, correlating with the amount of MOS in vivo. When wild-type and mutant plants were tested in conditions where both lines had similar MOS contents, no difference in amylose synthesis was observed. We also tested the hypothesis that branches of amylopectin might serve as the primers for granule-bound starch synthase I. In this model, elongated branches of amylopectin are subsequently cleaved to form amylose. We conducted pulse-chase experiments, supplying a pulse of ADP[14C]Glc to isolated starch granules or 14CO2 to intact plants, followed by a chase period in unlabeled substrate. We detected no transfer of label from the amylopectin fraction to the amylose fraction of starch either in isolated starch granules or in intact leaves, despite varying the time course of the experiments and using a mutant line (sex4) in which high-amylose starch is synthesized. We therefore find no evidence for amylopectin-primed amylose synthesis in Arabidopsis. We propose that MOS are the primers for amylose synthesis in Arabidopsis leaves. PMID:11891261

A Research Program in Computer Technology

DTIC Science & Technology

1975-09-01

Dale M. Chase Neil M. Goldman Jeannette Christen~sen Norton R. Green feld Kathie Cole grove John F. Heafner Nancy Dechter James Koda Oralio E. Garza...Thomas L. Boynton Stephen L. Casner E. Randolph Cole James Koda Robert Parker Paul Raveling Dono Van-Mierop Research Assistant: John K. Kastner

A Contemporary Blueprint for North Atlantic Treaty Organization Provisional Reconstruction Teams in Afghanistan?

DTIC Science & Technology

2006-05-25

States-led coalition, working in close cooperation with the Northern Alliance, succeeded in ousting the Taliban regime and chasing the remnants of its...Oxford University Press. Misra, Amalendu. 2004. Afghanistan: The Labyrinth of Violence. Cambridge, United Kingdom: Polity Press. Ralph, Magnus . 1998

Rogue States and Deterrence Strategy

DTIC Science & Technology

2009-04-02

United States leadership needs to recognize this recalcitrance- and stop condoning Iran’s behavior. Perkovich added, “we need to stop chasing them 20...1984), 141. 30 22 Magnus Ranstrop, “The Commission of Terrorist Attacks Upon the United States, March 31, 2003, http://www.9-11commission.gov/hearings

NOVA Fall 1998 Teacher's Guide.

ERIC Educational Resources Information Center

Colombo, Luann

This teacher's guide is designed to accompany the PBS television program "NOVA." Six science activities correspond to: (1) "Lost at Sea: The Search for Longitude,, which researches and charts the shortest course to circumnavigate the globe; (2) "Chasing El Nino," which formulates a question and designs an experiment to…

Chasing the Dream

ERIC Educational Resources Information Center

Gardezi, Aleena

2012-01-01

Community colleges are gearing up to play a greater role in providing open access and affordable education to undocumented immigrants since President Barack Obama's re-election, which ensured the continuance of his June 15th executive order offering deferred deportation to eligible young immigrants. That order provided an opportunity for children…

Cultivating Deductive Thinking with Angle Chasing

ERIC Educational Resources Information Center

Edwards, Michael todd; Quinlan, James; Harper, Suzanne R.; Cox, Dana C.; Phelps, Steve

2014-01-01

Despite Common Core State Standards for Mathematics (CCSSI 2010) recommendations, too often students' introduction to proof consists of the study of formal axiomatic systems--for example, triangle congruence proofs--typically in an introductory geometry course with no connection back to previous work in earlier algebra courses. Van Hiele…

All the King's Men.

ERIC Educational Resources Information Center

Seeberg, Mark S.

1980-01-01

Reports on a four-year-old, team-taught secondary interdisciplinary program that combined English, social studies, biology, and geometry. The course was organized into three phases: (1) the "Paper Chase," teaching learning skills; (2) "Welcome to the Monkey House," which addressed fundamental human issues; and (3) "Phase Out," or personal…

"Chasing a Passion": First-Generation College Graduates at Work

ERIC Educational Resources Information Center

Olson, Joann S.

2016-01-01

Purpose: The purpose of this paper is to describe the college-to-work transition as experienced by first-generation college (FGC) graduates. First-generation graduates are often adjusting to workplaces that are significantly different from parents' work environments. Design/methodology/approach: This phenomenological study explored the…

Chasing Shadows

ERIC Educational Resources Information Center

DeVore, Edna; Gould, Alan

2017-01-01

The solar eclipse coming August 21 offers students the opportunity not only to explore the geometry of the solar system but also to learn about exoplanets transiting distant stars. Students can glimpse a great frontier of science: the search for other worlds and life. This article presents information on exoplanets, discovering planets around…

Chasing Unachievable Outcomes

ERIC Educational Resources Information Center

Pangrazi, Robert P.

2010-01-01

Today, teachers complain about the lack of physical education time and the lack of physical education programming. In addition, a great deal of time is spent advocating the relationship between "healthy mind-healthy body." Today's drive to show a relationship between physical fitness/activity and academic achievement is really not different than…

American white pelicans breeding in the northern plains: productivity, behavior, movements, and migration

USGS Publications Warehouse

Sovada, Marsha A.; Pietz, Pamela J.; Woodward, Robert O.; Bartos, Alisa J.; Buhl, Deborah A.; Assenmacher, Michael J.

2013-01-01

Nearly half of American white pelicans (Pelecanus erythrorhynchos; hereafter pelicans) are believed to nest in several large colonies in the northern plains, yet few studies had been conducted on pelicans in this region until research began in 2004 to investigate the impact of West Nile virus (WNV) on their chicks. The work reported here focused on two of the largest colonies in the region, at Bitter Lake, South Dakota, and Chase Lake, North Dakota, during 2005–10. Pelicans usually began arriving at these two breeding colonies in early April. Egg-laying began during mid-April and nest initiations continued through May. The number of nests documented at these colonies reached a high of about 15,400 at Bitter Lake and 17,300 at Chase Lake, both in 2006. During 2006–8, annual variation in hatching success was high (40 to 100 percent) at video-monitored nests, averaging 61 percent for 82 nests at Bitter Lake and 57 percent for 88 nests at Chase Lake. Although most nests contained two eggs, of those where two chicks hatched, both chicks survived to the crèche stage (about 15 days old) at only two nests. Severe weather events, disturbance, and siblicide were documented causes of early season (before mid-July) mortalities. In the late season (mid-July to fledging), WNV was the most important factor contributing to chick mortality. Nests were nearly always attended by one adult during incubation and brooding. Adults typically exchanged places at the nest around mid-day in all 3 years, apparently taking advantage of thermals to gain altitude for travel to and from foraging areas. The mean time of exchange differed by about an hour between Bitter Lake (1328 central standard time, CST) and Chase Lake (1434 CST) colonies. During incubation, nearly 3 days often passed between adult nest exchanges; after chicks hatched, exchanges usually occurred daily. Exchanges were more frequent and chicks were fed more often at successful nests than at failed nests. Adult pelicans with satellite transmitters that incorporated a Global Positioning System (GPS) foraged primarily in shallow areas of lakes and semipermanent wetlands. These areas coincide with typical habitats of crayfish, salamanders, and rough fish, which were also the foods most commonly seen in pelican regurgitates at the colonies. Several satellite-tracked pelicans made frequent round trips between their breeding colony and foraging areas, most likely to provision their chicks. Typical distances travelled to foraging sites ranged from 30 kilometers to over 90 kilometers. Return times to the colonies (about 1300 and 1500 CST at Bitter Lake and Chase Lake, respectively) supported the colony difference documented at video-monitored nests. Of 28 pelicans tagged with GPS satellite transmitters in 2005–6, 26 survived the first summer and migrated south during fall. Nineteen of these returned to the breeding region (defined as north of the latitude of South Dakota’s southern border) in at least 1 year during 2006–9; collectively, they returned to the breeding region 33 times. Very few pelicans returned to the colony where they had been tagged; many did not breed and concentrated their activities at wetland complexes in South Dakota and North Dakota, but few tagged pelicans temporally overlapped at specific sites. During 2005–9, tagged pelicans collectively made 56 migratory trips south in the fall. Most wintered in Mexico, near the gulf coast and elsewhere; others wintered in Texas, Louisiana, Mississippi, and Florida. Individuals typically returned to the same general areas each winter. Individuals rarely followed the same migratory path on their way south and north, but they often roughly repeated southerly or northerly routes among years. Ensuring a sustainable population of American white pelicans requires identification and mitigation of known threats. The work described herein has identified WNV and severe weather as important factors that potentially limit reproductive success and recruitment in the northern plains. Managers in this region could assess the influence of such factors on productivity at key colonies by annually obtaining aerial photographs during peak nesting, and estimating numbers of chicks fledged from aerial photographs or ground counts. Banding a subsample of chicks in late June or early July, followed by a sweep for bands at the end of the season, would allow estimation of mortality rates of older chicks (that normally would fledge) and help track the influence of WNV or other mortality factors over time and varying environmental conditions.

Solar Eclipse

Atmospheric Science Data Center

2013-04-19

... June 10, 2002 the Moon obscured the central portion of the solar disk in a phenomenon known as an annular solar eclipse. Partial phases of ... to obscure about 75 percent of the solar disk. The two scenes are geolocated to adjacent paths within World Reference System-2. ...

Wet-Bulb-Globe Temperature Data Report

DTIC Science & Technology

2015-03-01

Hour Min Pressure Dry Nat Wet Globe Dry Nat Wet Globe Dry Nat Wet Globe Wind Cld amt Cld type Obscuration Quest RH Kestrel RH VPSc RH S1 WBGT Q WBGT...Wet Globe Dry Nat Wet Globe Dry Nat Wet Globe Wind Cld amt Cld type Obscuration Quest RH Kestrel RH VPSc RH S1 WBGT Q WBGT K2 WBGT GMT millibars deg F...Dry Nat Wet Globe Dry Nat Wet Globe Wind Cld amt Cld type Obscuration Quest RH Kestrel RH VPSc RH S1 WBGT Q WBGT K2 WBGT GMT millibars deg F deg F deg

AGN Obscuration Through Dusty Infrared Dominated Flows. 1; Radiation-Hydrodynamics Solution for the Wind

NASA Technical Reports Server (NTRS)

Dorodnitsyn, A.; Bisnovatyi-Kogan. G. S.; Kallman, T.

2011-01-01

We construct a radiation-hydrodynamics model for the obscuring toroidal structure in active galactic nuclei. In this model the obscuration is produced at parsec scale by a dense, dusty wind which is supported by infrared radiation pressure on dust grains. To find the distribution of radiation pressure, we numerically solve the 2D radiation transfer problem in a flux limited diffusion approximation. We iteratively couple the solution with calculations of stationary 1D models for the wind, and obtain the z-component of the velocity. Our results demonstrate that for AGN luminosities greater than 0.1 L(sub edd) external illumination can support a geometrically thick obscuration via outflows driven by infrared radiation pressure. The terminal velocity of marginally Compton-thin models (0.2 < tau(sub T) < 0.6), is comparable to or greater than the escape velocity. In Compton thick models the maximum value of the vertical component of the velocity is lower than the escape velocity, suggesting that a significant part of our torus is in the form of failed wind. The results demonstrate that obscuration via normal or failed infrared-driven winds is a viable option for the AGN torus problem and AGN unification models. Such winds can also provide an important channel for AGN feedback.

Space Telescope and Optical Reverberation Mapping Project VI. Variations of the Intrinsic Absorption Lines in NGC 5548

NASA Astrophysics Data System (ADS)

Kriss, Gerard A.; Agn Storm Team

2015-01-01

The AGN STORM collaboration monitored the Seyfert 1 galaxy NGC 5548 over a six-month period, with observations spanning the hard X-ray to mid-infrared wavebands. The core of this campaign was an intensive HST COS program, which obtained 170 far-ultraviolet spectra at approximately daily intervals, with twice-per-day monitoring of the X-ray, near-UV, and optical bands during much of the same period using Swift. The broad UV absorption lines discovered by Kaastra et al. (2014) and associated with the new soft X-ray obscurer are continuously present in the STORM campaign COS spectra. Their strength varies with the degree of soft X-ray obscuration as revealed by the Swift X-ray spectra. The narrow associated absorption lines in the UV spectrum of NGC 5548 remain strong. The lower-ionization transitions that appeared concurrently with the soft X-ray obscuration vary in response to the changing UV flux on a daily basis. Their depths over the longer term, however, also respond to the strength of the soft X-ray obscuration, indicating that the soft X-ray obscurer has a significant influence on the ionizing UV continuum that is not directly tracked by the observable UV continuum itself.

Dust-obscured Galaxies in the Local Universe

NASA Astrophysics Data System (ADS)

Hwang, Ho Seong; Geller, Margaret J.

2013-06-01

We use Wide-field Infrared Survey Explorer (WISE), AKARI, and Galaxy Evolution Explorer (GALEX) data to select local analogs of high-redshift (z ~ 2) dust obscured galaxies (DOGs). We identify 47 local DOGs with S 12 μm/S 0.22 μm >= 892 and S 12 μm > 20 mJy at 0.05 < z < 0.08 in the Sloan Digital Sky Survey data release 7. The infrared (IR) luminosities of these DOGs are in the range 3.4 × 1010 (L ⊙) <~ L IR <~ 7.0 × 1011 (L ⊙) with a median L IR of 2.1 × 1011 (L ⊙). We compare the physical properties of local DOGs with a control sample of galaxies that have lower S 12 μm/S 0.22 μm but have similar redshift, IR luminosity, and stellar mass distributions. Both WISE 12 μm and GALEX near-ultraviolet (NUV) flux densities of DOGs differ from the control sample of galaxies, but the difference is much larger in the NUV. Among the 47 DOGs, 36% ± 7% have small axis ratios in the optical (i.e., b/a < 0.6), larger than the fraction among the control sample (17% ± 3%). There is no obvious sign of interaction for many local DOGs. No local DOGs have companions with comparable optical magnitudes closer than ~50 kpc. The large- and small-scale environments of DOGs are similar to the control sample. Many physical properties of local DOGs are similar to those of high-z DOGs, even though the IR luminosities of local objects are an order of magnitude lower than for the high-z objects: the presence of two classes (active galactic nuclei- and star formation-dominated) of DOGs, abnormal faintness in the UV rather than extreme brightness in the mid-IR, and diverse optical morphology. These results suggest a common underlying physical origin of local and high-z DOGs. Both seem to represent the high-end tail of the dust obscuration distribution resulting from various physical mechanisms rather than a unique phase of galaxy evolution.

Preparation and properties on hollow nano-structured smoke material

NASA Astrophysics Data System (ADS)

Liu, Xiang-cui; Dai, Meng-yan; Fang, Guo-feng; Shi, Wei-dong; Cheng, Xiang; Liu, Hai-feng; Zhang, Tong

2013-09-01

In recent years, the weapon systems of laser guidance and infrared (IR) imaging guidance have been widely used in modern warfare because of their high precision and strong anti-interference. Notwithstanding, military smoke, as a rapid and effective passive jamming means, can effectively counteract the attack of enemy precision-guided weapons by scattering and absorbability. Conventional smoke has good attenuation capability only to visible light (0.4-0.76 μm), but hardly any effect to other electromagnetic wave band. The weapon systems of laser guidance and IR imaging guidance usually work in broad band, including near IR (1-3 μm), middle IR (3-5 μm), far IR (8-14 μm), and so on. Accordingly, exploiting and using new efficient obscurant materials, which is one of the important factors that develop smoke technology, have become a focus and attracted more interests around the world. Then nano-structured materials that are developing very quickly have turned into our new choice. Hollow nano-structured materials (HNSM) have many special properties because of their nano-size wall-thickness and sub-micron grain-size. After a lot of HNSM were synthesized in this paper, their physical and chemical properties, including grain size, phase composition, microstructure, optical properties and resistivity were tested and analysed. Then the experimental results of the optical properties showed that HNSM exhibit excellent wave-absorbing ability in ultraviolet, visible and infrared regions. On the basis of the physicochemmical properties, HNSM are firstly applied in smoke technology field. And the obscuration performance of HNSM smoke was tested in smoke chamber. The testing waveband included 1.06μm and 10.6μm laser, 3-5μm and 8-14μm IR radiation. Then the main parameters were obtained, including the attenuation rate, the transmission rate, the mass extinction coefficient, the efficiency obscuring time, and the sedimentation rate, etc. The main parameters of HNSM smoke were contrasted in detail with graphite powder smoke agent. The results showed that HNSM smoke possesses better obscuration capability compared with the smoke performance of conventional materials (such as HC, RP, oil, carbon black, and graphite powder). Therefore, they are new smoke obscurant materials which can effectively interfere with broadband electromagnetic radiation, including 1.06 μm and 10.6 μm laser, 3-5 μm and 8-14 μm IR waveband.

The distant red galaxy neighbour population of 1 <~ z <~ 2 QSOs and optically obscured sources

NASA Astrophysics Data System (ADS)

Bornancini, Carlos G.; García Lambas, Diego

2007-05-01

We study the distant red galaxy (DRG; J - Ks > 2.3) neighbour population of quasi-stellar objects (QSOs) selected from the Sloan Digital Sky Survey (SDSS) in the redshift range 1 <~ z <~ 2. We perform a similar analysis for optically obscured active galactic nuclei (AGNs; i.e. with a limiting magnitude I > 24) detected in the mid-infrared (24 μm) with the Spitzer Space Telescope and a mean redshift z ~ 2.2 in the Flamingos Extragalactic Survey (FLAMEX). Both QSOs and obscured AGN target samples cover 4.7 deg2 in the same region of the sky. We find a significant difference in the environment of these two target samples. Neighbouring galaxies close to QSOs tend to be bluer than galaxies in optically obscured source environments. We also present results on the cross-correlation function of DRGs around QSOs and optically faint mid-infrared sources. The corresponding correlation length obtained for the QSO sample targets is r0 = 5.4 +/- 1.6 Mpc h-1 and a slope of γ = 1.94 +/- 0.10. For the optically obscured galaxy sample, we find r0 = 8.9 +/- 1.4 Mpc h-1 and a slope of γ = 2.27 +/- 0.20. These results indicate that optically faint obscured sources are located in denser environment of evolved red galaxies compared to QSOs. Based on observations and/or data products by the Flamingos Extragalactic Survey. FLAMINGOS was designed and constructed by the IR instrumentation group (PI: R. Elston) at the University of Florida, Department of Astronomy, with support from NSF grant AST97-31180 and Kitt Peak National Observatory. E-mail: bornancini@oac.uncor.edu

An unbiased view of X-ray obscuration amongst active galactic nuclei with NuLANDS

NASA Astrophysics Data System (ADS)

Boorman, Peter Gregory; Gandhi, Poshak; Stern, Daniel; Harrison, Fiona; NuSTAR Obscured AGN Team

2018-01-01

Nearly all active galactic nuclei (AGN) are obscured in X-rays behind column densities of NH ≥ 1022 cm-2. Hard X-ray studies have proven very effective to quanitfy the levels of obscuration amongst AGN, up to and just above the Compton-thick limit (NH ˜ 1.5 × 1024 cm-2). However, Compton-thick sources with NH values beyond this limit are typically missed in hard X-ray all-sky surveys such as Swift/BAT, requiring many studies to apply considerable bias corrections to account for the loss. Incorrectly quanitfying the heavily obscured AGN population can have a dramatic effect on synthesis models designed to fit the Cosmic X-ray Background spectrum, due to their significant contribution to the peak flux of the background at ~30 keV. This is what motivated the NuSTAR Local AGN NH Distribution Survey (NuLANDS) - a NuSTAR 1 Ms legacy survey of an obscuration-independent, infrared selected sample of AGN, undetected by BAT and unobserved by NuSTAR before - a considerable number of which are predicted to be heavily obscured. NuSTAR is the first true X-ray focusing instrument capable of spectral analysis > 10 keV, and as such can and will place robust constraints on the NH values of these elusive AGN. In this poster, I will present the first results from NuLANDS, including multiple newly identified Compton-thick AGN, previously undetected in the Swift/BAT 70-month catalog. I will further highlight the exciting prospects for the complete NuLANDS sample, with the ultimate goal of constructing a representative NH distribution of AGN in the local Universe, requiring minimal bias corrections.

EVIDENCE FOR A WIDE RANGE OF ULTRAVIOLET OBSCURATION IN z {approx} 2 DUSTY GALAXIES FROM THE GOODS-HERSCHEL SURVEY

DOE Office of Scientific and Technical Information (OSTI.GOV)

Penner, Kyle; Dickinson, Mark; Dey, Arjun

Dusty galaxies at z {approx} 2 span a wide range of relative brightness between rest-frame mid-infrared (8 {mu}m) and ultraviolet wavelengths. We attempt to determine the physical mechanism responsible for this diversity. Dust-obscured galaxies (DOGs), which have rest-frame mid-IR to UV flux density ratios {approx}> 1000, might be abnormally bright in the mid-IR, perhaps due to prominent emission from active galactic nuclei and/or polycyclic aromatic hydrocarbons, or abnormally faint in the UV. We use far-infrared data from the GOODS-Herschel survey to show that most DOGs with 10{sup 12} L {sub Sun} {approx}< L {sub IR} {approx}< 10{sup 13} L {submore » Sun} are not abnormally bright in the mid-IR when compared to other dusty galaxies with similar IR (8-1000 {mu}m) luminosities. We observe a relation between the median IR to UV luminosity ratios and the median UV continuum power-law indices for these galaxies, and we find that only 24% have specific star formation rates that indicate the dominance of compact star-forming regions. This circumstantial evidence supports the idea that the UV- and IR-emitting regions in these galaxies are spatially coincident, which implies a connection between the abnormal UV faintness of DOGs and dust obscuration. We conclude that the range in rest-frame mid-IR to UV flux density ratios spanned by dusty galaxies at z {approx} 2 is due to differing amounts of UV obscuration. Of galaxies with these IR luminosities, DOGs are the most obscured. We attribute differences in UV obscuration to either (1) differences in the degree of alignment between the spatial distributions of dust and massive stars or (2) differences in the total dust content.« less

Oscillations and Analogies: Thomas Young, MD, FRS, Genius.

ERIC Educational Resources Information Center

Martindale, Colin

2001-01-01

Thomas Young was a renowned genius in his time who did important work in many scientific disciplines. In today's specialized environment, scientists in each discipline do not appreciate his work. Despite his current obscurity, Young exemplifies traits found in a first-order genius (analogical thinking, high intelligence, hard work, wide interests,…

Making American Literatures in High School and College. Classroom Practices in Teaching English, Volume 31.

ERIC Educational Resources Information Center

Gere, Anne Ruggles, Ed.; Shaheen, Peter, Ed.

This book is a collection of classroom-tested ideas for helping students explore how literature and "the canon" are made, what the term "American" means, and how the phrase "American literature" obscures the presence of multiple "literatures" that are both individually compelling and mutually enriching. Each…

Issues 2016: Is There a Student Debt Crisis?

ERIC Educational Resources Information Center

Eden, Max

2016-01-01

Student debt is a convenient target in a presidential election year, but it obscures the true crisis: high dropout rates from low-quality postsecondary institutions and the unmanageable debt borne by students of those institutions. And despite rising student debt, monthly loan payments as a share of income have remained steady, added earnings…

Simultaneous Chandra and NuSTAR Observations of the Highly Obscured AGN Candidate in NGC660.

NASA Astrophysics Data System (ADS)

Annuar, Ady

2014-09-01

We are using NuSTAR to undertake a detailed investigation of the obscured AGN population at D<15Mpc. Our latest target is NGC660 where the presence of an AGN has been ambiguous. However, recently it was observed to undergo a radio outburst which reveals a bright continuum source (Argo et al. 2015), coincident with Chandra 2-8 keV emission from one of the three point sources near the nucleus (<5"). This confirms and pinpoints the X-ray position of the AGN. Comparisons of the Chandra flux with the radio emission and other multiwavelength luminosity indicators indicate that the X-ray flux is suppressed, suggesting that it is absorbed by a high column of gas. A NuSTAR observation for this object has been scheduled as part of our program. The requested Chandra observation is essential to unambiguously constrain the AGN and isolate it from other sources at <8 keV. When combined with NuSTAR, we will then be able to accurately characterise the 0.5-30 keV spectrum of the AGN for the first time.

Discovery of a red quasar with recurrent activity

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nandi, S.; Baes, M.; Gentile, G.

2014-07-01

We report a new double-double radio quasar (DDRQ) J0746+4526 which exhibits two cycles of episodic activity. From radio continuum observations at 607 MHz using the Giant Metrewave Radio Telescope and 1400 MHz from the Faint Images of the Radio Sky at Twenty-cm survey we confirm its episodic nature. We examine the Sloan Digital Sky Survey (SDSS) optical spectrum and estimate the black hole mass to be (8.2 ± 0.3)×10{sup 7} M {sub ☉} from its observed Mg II emission line, and the Eddington ratio to be 0.03. The black hole mass is significantly smaller than for the other reported DDRQ,more » J0935+0204, while the Eddington ratios are comparable. The SDSS spectrum is significantly red-continuum-dominated, suggesting that it is highly obscured with E(B – V){sub host} = 0.70 ± 0.16 mag. This high obscuration further indicates the existence of a large quantity of dust and gas along the line of sight, which may have a key role in triggering the recurrent jet activity in such objects.« less

How We Think and Learn. Lecture Series.

ERIC Educational Resources Information Center

National Learning Center, Washington, DC.

A lecture series was conducted in 1989 to present information on learning theories by learning theorists. This document contains short texts of the lectures; full texts are available on request. In lecture 1, Robert Chase discusses educational reform and Bonnie Guiton examines educational goals from the perspective of White House policy. In…

Using a Computer Game to Reinforce Skills in Addition Basic Facts in Second Grade.

ERIC Educational Resources Information Center

Kraus, William H.

1981-01-01

A computer-generated game called Fish Chase was developed to present drill-and-practice exercises on addition facts. The subjects of the study were 19 second-grade pupils. The results indicate a computer game can be used effectively to increase proficiency with basic facts. (MP)

Chameleon Chasing II: A Replication.

ERIC Educational Resources Information Center

Newsom, Doug A.; And Others

1993-01-01

Replicates a 1972 survey of students, educators, and Public Relations Society of America members regarding who the public relations counselor really serves. Finds that, in 1992, most respondents thought primary responsibility was to the client, then to the client's relevant publics, then to self, then to society, and finally to media. Compares…

Library Students Are "Breaking Good" with Saul Goodman's Advice

ERIC Educational Resources Information Center

Turkewitz, Deborah

2014-01-01

Graduate students are taking big steps and stretching themselves, whether returning to school midpoint in their lives, taking classes on unfamiliar topics, or starting internships and trying to put theory into practice. Who better to offer advice to these graduate students than America's favorite hilarious, morally ambiguous, ambulance-chasing,…

75 FR 75698 - Sunshine Act Notice

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-06

... DEPARTMENT OF JUSTICE Parole Commission Sunshine Act Notice Public Announcement; Pursuant to the Government in the Sunshine Act (Pub. L. 94-409) [5 U.S.C. Section 552b] DATE AND TIME: 12 a.m., Tuesday, December 7, 2010. PLACE: U.S. Parole Commission, 5550 Friendship Boulevard, 4th Floor Chevy Chase, Maryland...

Integrating Literature and Mathematics: A Mysterious Connection

ERIC Educational Resources Information Center

Wilburne, Jane Murphy; Napoli, Mary

2007-01-01

This article describes a mathematics and literature interdisciplinary project for preservice elementary teachers that was implemented in several urban middle school classrooms. This project, based on the novel Chasing Vermeer by Balliett (2004), involved a dramatization of one of the chapters from the book and a follow-up mathematical exploration.

A Historical Omission

ERIC Educational Resources Information Center

Stuart, Reginald

2007-01-01

For nearly a decade, Dr. Maggie Rivas-Rodriguez and a small army of students and volunteer colleagues around the country have been aggressively chasing and documenting a rapidly vanishing chapter of American history--the American Latino and Latina experience during World War II. Along the way, they recorded nearly 600 interviews of about two…

4. Northeast corner of quarters (executive officer's quarters), looking onto ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

4. Northeast corner of quarters (executive officer's quarters), looking onto Quarter R (commanding officer's quarters), looking southeast - Naval Air Station Chase Field, Texas State Highway 202, 4.8 miles east of intersection of Texas State Highway 202 & U.S. State Highway 181, Beeville, Bee County, TX

2. Overview of Buildings 2015, 2133 and 2009, with Building ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

2. Overview of Buildings 2015, 2133 and 2009, with Building 1001 (administration building) in background, looking northeast - Naval Air Station Chase Field, Texas State Highway 202, 4.8 miles east of intersection of Texas State Highway 202 & U.S. State Highway 181, Beeville, Bee County, TX

77 FR 71365 - Proposed Establishment of Class E Airspace; Beeville, TX

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-30

... accommodate new Standard Instrument Approach Procedures (SIAPs) at Chase Field Industrial Airport. The FAA is taking this action to enhance the safety and management of Instrument Flight Rules (IFR) operations for.... ADDRESSES: Send comments on this proposal to the U.S. Department of [[Page 71366

29. PLAN OF THE ARVFS FIELD TEST FACILITY SHOWING BUNKER, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

29. PLAN OF THE ARVFS FIELD TEST FACILITY SHOWING BUNKER, CABLE CHASE, SHIELDING TANK AND FRAME ASSEMBLY. F.C. TORKELSON DRAWING NUMBER 842-ARVFS-701-1. INEL INDEX CODE NUMBER: 075 0701 851 151970. - Idaho National Engineering Laboratory, Advanced Reentry Vehicle Fusing System, Scoville, Butte County, ID

North Carolina's Approach: Developing a Bio-Tech Workforce

ERIC Educational Resources Information Center

Smit, Norman

2004-01-01

States across the country are all chasing what are becoming known as "new-age" technologies. These are technologies such as biotechnology, nanotechnology, bio-informatics and others. These technologies offer the potential for long-term economic growth and well-paid jobs to employees working in these sectors. As these technologies mature,…

Autoradiography and the Cell Cycle.

ERIC Educational Resources Information Center

Jones, C. Weldon

1992-01-01

Outlines the stages of a cell biology "pulse-chase" experiment in which the students apply autoradiography techniques to learn about the concept of the cell cycle. Includes (1) seed germination and plant growth; (2) radioactive labeling and fixation of root tips; (3) feulgen staining of root tips; (4) preparation of autoradiograms; and…

An updated comprehensive annotated list of the butterflies (Lepidoptera: Rhopalocera) occurring at Chase Lake National Wildlife Refuge Complex Stutsman County, North Dakota 1995-1996

USGS Publications Warehouse

Royer, Ron

1996-01-01

A project to produce a comprehensive, site-specific butterfly list that could serve as a basis for future monitoring of butterfly populations and as an aid in making management decisions for the area.

Chasing the Wolves from the Schoolhouse Door.

ERIC Educational Resources Information Center

Kowalski, Theodore

1995-01-01

Warnings about the deterioration of America's schoolhouses have generated only limited public reaction. State legislators, governors, federal officials, and corporate executives who reacted to "A Nation at Risk" have remained silent--perhaps because lots of money is needed to fix the problem. This article explains the effects of physical…

Responding to the Novel: Reading, Writing, and Research.

ERIC Educational Resources Information Center

Polette, Nancy

1991-01-01

Discusses approaches to novel studies for children and youth and provides a fully developed novel study based on "The Wolves of Willoughby Chase" by Joan Aiken. Prereading activities are described, a booktalk is provided, prereading journal suggestions are given, postreading activities are described, and related reading titles are…

Problem-Based Test: Replication of Mitochondrial DNA during the Cell Cycle

ERIC Educational Resources Information Center

Setalo, Gyorgy, Jr.

2013-01-01

Terms to be familiar with before you start to solve the test: cell cycle, generation time, S-phase, cell culture synchronization, isotopic pulse-chase labeling, density labeling, equilibrium density-gradient centrifugation, buoyant density, rate-zonal centrifugation, nucleoside, nucleotide, kinase enzymes, polymerization of nucleic acids,…

GISD

Science.gov Websites

GISD Global invasive species database Home About the GISD How to use Contacts 100 of the worst ) Bromus rubens Line drawing of Bromus rubens (USDA-NRCS PLANTS Database / Hitchcock, A.S. (rev. A. Chase GISD ISPRA SNPA The Global Invasive Species Database was developed and is managed by the Invasive

Inclusion Strategies for Students with Learning and Behavior Problems: Perspectives, Experiences, and Best Practices.

ERIC Educational Resources Information Center

Zionts, Paul, Ed.

This book presents discussions of the practical implementation of inclusion principles with students having learning and/or behavioral problems and disorders. The chapters, arranged under two topical units, "Perspectives and Experiences" and "Best Practices" are: (1) "Inclusion: Chasing the Impossible Dream? Maybe"…

Oracy II.

ERIC Educational Resources Information Center

Nebraska Univ., Lincoln.

This volume on the Tri-University project contains three reports on the teaching of oracy. The chairman of the committee on oracy, Laura Chase, offers suggestions for the preservice and inservice training of teachers to prepare them to deal with discussion, the individual talk, oral reading, and dramatic role playing. She outlines a teacher…

Global Proliferation-Dynamics, Acquisition Strategies, and Responses. Volume 2. Nuclear Proliferation

DTIC Science & Technology

1994-09-01

due to Marvin Atkins, Joel Bengston. Richard Blumstein. John Bulger, James Bushong, Burrus Carnahan, Alexis Castor, Emerory Chase, Edward Chaves...SCIENCE BOARDATTN: DR P G K MINSKI OSD (DDR&E) ATTN: DR VICTOR REIS DEPUTY ASSISTANT SECRETARY OSD COMPTROLLER ATTN: JANE MATTHIAS ATTN: HONORABLE JOHN

Prime Contractors | Division of Cancer Prevention

Cancer.gov

2015-2018 Efficacy and Intermediate Endpoint Biomarkers: The Research Institute of Fox Chase Cancer Center SRI International IIT Research Institute University of Texas MD Anderson Cancer Center University of Alabama at Birmingham Medical College of Wisconsin University of Oklahoma Health Sciences Center Weill Medical College of Cornell University Toxicology and Pharmacology

77 FR 70141 - Application(s) for Duty-Free Entry of Scientific Instruments

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-23

... Institute, 4000 Jones Bridge Rd., Chevy Chase, MD 20815. Instrument: Micro-litre and nanolitre dispensing...-litre and nanolitre dispensing system. Manufacturer: TTP Labtech Ltd, United Kingdom. Intended Use: The...: The instrument will be used to study biomaterials such as starches, lignin, and proteins, and compare...

X-ray View of Four High-Luminosity Swift-BAT AGN: Unveiling Obscuration and Reflection with Suzaku

NASA Technical Reports Server (NTRS)

Fiorettil, V.; Angelini, L.; Mushotzky, R. F.; Koss, M.; Malaguti, G.

2013-01-01

Aims. A complete census of obscured Active Galactic Nuclei (AGN) is necessary to reveal the history of the super massive black hole (SMBH) growth and galaxy evolution in the Universe given the complex feedback processes and the fact that much of this growth occurs in an obscured phase. In this context, hard X-ray surveys and dedicated follow-up observations represent a unique tool for selecting highly absorbed AGN and for characterizing the obscuring matter surrounding the SMBH. Here we focus on the absorption and reflection occurring in highly luminous, quasar-like AGN, to study the relation between the geometry of the absorbing matter and the AGN nature (e.g. X-ray, optical, and radio properties), and to help to determine the column density dependency on the AGN luminosity. Methods. The Swift/BAT nine-month survey observed 153 AGN, all with ultra-hard X-ray BAT fluxes in excess of 10(exp -11) erg per square centimeter and an average redshift of 0.03. Among them, four of the most luminous BAT AGN (44.73 less than LogLBAT less than 45.31) were selected as targets of Suzaku follow-up observations: J2246.0+3941 (3C 452), J0407.4+0339 (3C 105), J0318.7+6828, and J0918.5+0425. The column density, scattered/reflected emission, the properties of the Fe K line, and a possible variability are fully analyzed. For the latter, the spectral properties from Chandra, XMM-Newton and Swift/XRT public observations were compared with the present Suzaku analysis, adding an original spectral analysis when non was available from the literature. Results. Of our sample, 3C 452 is the only certain Compton-thick AGN candidate because of i) the high absorption (N(sub H) approximately 4 × 10(exp 23) per square centimeter) and strong Compton reflection; ii) the lack of variability; iii) the "buried" nature, i.e. the low scattering fraction (less than 0.5%) and the extremely low relative [OIII] luminosity. In contrast 3C 105 is not reflection-dominated, despite the comparable column density, X-ray luminosity and radio morphology, but shows a strong long-term variability in flux and scattering fraction, consistent with the soft emission being scattered from a distant region (e.g., the narrow emission line region). The sample presents high (greater than 100) X-to- [OIII] luminosity ratios, with an extreme value of R(sup X)(sub [OIII]) approximately 800 for 3C 452, confirming the [OIII] luminosity to be affected by residual extinction in presence of mild absorption, especially for "buried" AGN such as 3C 452. Three of our targets are powerful FRII radio galaxies, which is shown by their high luminosity and absorption; this makes them the most luminous and absorbed AGN of the BAT Seyfert survey despite the inversely proportional N(sub H) - L(sub X) relation.

NGC1448 and IC 3639: Two Concealed Black Holes Lurking in our Cosmic Backyard Unveiled by NuSTAR

NASA Astrophysics Data System (ADS)

Stern, Daniel; Boorman, Peter; Annuar, Ady; Gandhi, Poshak; Alexander, D. M.; Lansbury, George B.; Asmus, Daniel; Ballantyne, David R.; Bauer, Franz E.; Boggs, Steven E.; Brandt, W. Niel; Brightman, Murray; Christensen, Finn; Craig, William W.; Farrah, Duncan; Goulding, Andy D.; Hailey, Charles James; Harrison, Fiona; Hoenig, Sebastian; Koss, Michael; LaMassa, Stephanie M.; Masini, Alberto; Murray, Stephen S.; Ricci, Claudio; Risaliti, Guido; Rosario, David J.; Stanley, Flora; Zhang, William

2017-01-01

We present NuSTAR observations of two nearby Active Galactic Nuclei (AGN), NGC 1448 and IC 3639, located at distances of 12 Mpc and 54 Mpc, respectively. NuSTAR high-energy X-ray (> 10 keV) observations, combined with archival lower energy X-ray observations from Chandra and Suzaku, reveal both sources to contain heavily obscured, accreting super-massive black holes. NGC 1448 is one of the nearest luminous galaxies to the Milky Way, yet the AGN at its centre was only discovered in 2009. Using state-of-the-art models, we constrain the obscuring column density (NH) of gas concealing both AGN, finding them to be extreme, with NH values well into the Compton-thick (CT) regime with N(H) > 3e24 /cm2. NGC 1448 has an intrinsic X-ray luminosity of L(24 keV) ˜ 5e40 erg/s, making it one of the lowest luminosity CT AGN known. IC 3639, on the other hand, has one of the strongest iron fluorescence emission lines known. We also discuss multi-wavelength diagnostics at optical and mid-infrared energies as indirect indicators to penetrate through the obscuring veils and probe the intrinsic properties of the AGN. Through detailed studies such as we present here, NuSTAR is showing that there are still plenty of interesting discoveries awaiting to be made, even in the nearby Universe.

A Submillimeter Survey of Dust Continuum Emission in Local Dust-Obscured Galaxies

NASA Astrophysics Data System (ADS)

Lee, Jong Chul; Hwang, Ho Seong; Lee, Gwang-Ho

2015-08-01

Dusty star-forming galaxies are responsible for the bulk of cosmic star formation at 1

Contingency blindness: location-identity binding mismatches obscure awareness of spatial contingencies and produce profound interference in visual working memory.

PubMed

Fiacconi, Chris M; Milliken, Bruce

2012-08-01

The purpose of the present study was to highlight the role of location-identity binding mismatches in obscuring explicit awareness of a strong contingency. In a spatial-priming procedure, we introduced a high likelihood of location-repeat trials. Experiments 1, 2a, and 2b demonstrated that participants' explicit awareness of this contingency was heavily influenced by the local match in location-identity bindings. In Experiment 3, we sought to determine why location-identity binding mismatches produce such low levels of contingency awareness. Our results suggest that binding mismatches can interfere substantially with visual-memory performance. We attribute the low levels of contingency awareness to participants' inability to remember the critical location-identity binding in the prime on a trial-to-trial basis. These results imply a close interplay between object files and visual working memory.

Compton thick AGN in Chandra sureys

NASA Astrophysics Data System (ADS)

Brightman, Murray; Nandra, Kirpal

2014-07-01

We present the results from the X-ray spectral analysis of active galactic nuclei (AGN) in the Chandra Deep Field-South, AEGIS-XD and Chandra-COSMOS surveys, focussing on the identification and characterisation of the most heavily obscured, Compton thick (CT, N H > 104 cm-2) sources. Our sample is comprised of 3088 X-ray selected sources, which has a high rate of redshift completeness (97%). The aim is to produce the largest and cleanest uniform sample of these sources from the data as possible. We identify these sources through X-ray spectral fitting, utilising torus spectral models designed for heavily obscured AGN which self consistently include the spectral signatures of heavy absorption, being Compton scattering, photoelectric absorption and iron Kα fluorescence. We identify a total of 163 CT AGN covering an intrinsic 2-10 keV X-ray luminosity range of 102 -3 × 105 erg s-1 and from z = 0.1-7.

Genetic fallout in biocultural landscapes: molecular imperialism and the cultural politics of (not) seeing transgenes in Mexico.

PubMed

Christophe Bonneuil; Foyer, Jean; Wynne, Brian

2014-12-01

This article explores the trajectory of the global controversy over the introgression (or not) of transgenes from genetically modified maize into Mexican indigenous maize landraces. While a plurality of knowledge-making processes were deployed to render transgenes visible or invisible, we analyze how a particular in vitro based DNA-centered knowledge came to marginalize other forms of knowledge, thus obscuring other bio-cultural dimensions key to the understanding of gene flow and maize diversity. We show that dominant molecular norms of proof and standards of detection, which co-developed with the world of industrial monocropping and gene patenting, discarded and externalized non-compliant actors (i.e. complex maize genomes, human dimensions of gene flow). Operating in the name of high science, they hence obscured the complex biological and cultural processes that maintain crop diversity and enacted a cultural-political domination over the world of Mexican landraces and indigenous communities.

Mid-infrared luminous quasars in the GOODS-Herschel fields: a large population of heavily obscured, Compton-thick quasars at z ≈ 2

NASA Astrophysics Data System (ADS)

Del Moro, A.; Alexander, D. M.; Bauer, F. E.; Daddi, E.; Kocevski, D. D.; McIntosh, D. H.; Stanley, F.; Brandt, W. N.; Elbaz, D.; Harrison, C. M.; Luo, B.; Mullaney, J. R.; Xue, Y. Q.

2016-02-01

We present the infrared (IR) and X-ray properties of a sample of 33 mid-IR luminous quasars (νL6 μm ≥ 6 × 1044 erg s-1) at redshift z ≈ 1-3, identified through detailed spectral energy distribution analyses of distant star-forming galaxies, using the deepest IR data from Spitzer and Herschel in the GOODS-Herschel fields. The aim is to constrain the fraction of obscured, and Compton-thick (CT, NH > 1.5 × 1024 cm-2) quasars at the peak era of nuclear and star formation activities. Despite being very bright in the mid-IR band, ≈30 per cent of these quasars are not detected in the extremely deep 2 and 4 Ms Chandra X-ray data available in these fields. X-ray spectral analysis of the detected sources reveals that the majority (≈67 per cent) are obscured by column densities NH > 1022 cm-2; this fraction reaches ≈80 per cent when including the X-ray-undetected sources (9 out of 33), which are likely to be the most heavily obscured, CT quasars. We constrain the fraction of CT quasars in our sample to be ≈24-48 per cent, and their space density to be Φ = (6.7 ± 2.2) × 10-6 Mpc-3. From the investigation of the quasar host galaxies in terms of star formation rates (SFRs) and morphological distortions, as a sign of galaxy mergers/interactions, we do not find any direct relation between SFRs and quasar luminosity or X-ray obscuration. On the other hand, there is tentative evidence that the most heavily obscured quasars have, on average, more disturbed morphologies than the unobscured/moderately obscured quasar hosts, which preferentially live in undisturbed systems. However, the fraction of quasars with disturbed morphology amongst the whole sample is ≈40 per cent, suggesting that galaxy mergers are not the main fuelling mechanism of quasars at z ≈ 2.

THE XMM-NEWTON WIDE-FIELD SURVEY IN THE COSMOS FIELD (XMM-COSMOS): DEMOGRAPHY AND MULTIWAVELENGTH PROPERTIES OF OBSCURED AND UNOBSCURED LUMINOUS ACTIVE GALACTIC NUCLEI

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brusa, M.; Cappelluti, N.; Merloni, A.

2010-06-10

We report the final optical identifications of the medium-depth ({approx}60 ks), contiguous (2 deg{sup 2}) XMM-Newton survey of the COSMOS field. XMM-Newton has detected {approx}1800 X-ray sources down to limiting fluxes of {approx}5 x 10{sup -16}, {approx}3 x 10{sup -15}, and {approx}7 x 10{sup -15} erg cm{sup -2} s{sup -1} in the 0.5-2 keV, 2-10 keV, and 5-10 keV bands, respectively ({approx}1 x 10{sup -15}, {approx}6 x 10{sup -15}, and {approx}1 x 10{sup -14} erg cm{sup -2} s{sup -1}, in the three bands, respectively, over 50% of the area). The work is complemented by an extensive collection of multiwavelength datamore » from 24 {mu}m to UV, available from the COSMOS survey, for each of the X-ray sources, including spectroscopic redshifts for {approx}>50% of the sample, and high-quality photometric redshifts for the rest. The XMM and multiwavelength flux limits are well matched: 1760 (98%) of the X-ray sources have optical counterparts, 1711 ({approx}95%) have IRAC counterparts, and 1394 ({approx}78%) have MIPS 24 {mu}m detections. Thanks to the redshift completeness (almost 100%) we were able to constrain the high-luminosity tail of the X-ray luminosity function confirming that the peak of the number density of log L{sub X} > 44.5 active galactic nuclei (AGNs) is at z {approx} 2. Spectroscopically identified obscured and unobscured AGNs, as well as normal and star-forming galaxies, present well-defined optical and infrared properties. We devised a robust method to identify a sample of {approx}150 high-redshift (z > 1), obscured AGN candidates for which optical spectroscopy is not available. We were able to determine that the fraction of the obscured AGN population at the highest (L{sub X} > 10{sup 44} erg s{sup -1}) X-ray luminosity is {approx}15%-30% when selection effects are taken into account, providing an important observational constraint for X-ray background synthesis. We studied in detail the optical spectrum and the overall spectral energy distribution of a prototypical Type 2 QSO, caught in a stage transitioning from being starburst dominated to AGN dominated, which was possible to isolate only thanks to the combination of X-ray and infrared observations.« less

The biosynthesis, processing, and secretion of laminin by human choriocarcinoma cells.

PubMed

Peters, B P; Hartle, R J; Krzesicki, R F; Kroll, T G; Perini, F; Balun, J E; Goldstein, I J; Ruddon, R W

1985-11-25

Laminin, a glycoprotein component of basal laminae, is synthesized and secreted in culture by a human malignant cell line (JAR) derived from gestational choriocarcinoma. Biosynthetically labeled human laminin subunits A (Mr approximately 400,000) and B (Mr = 200,000 doublet) are glycoslyated with asparagine-linked high mannose oligosaccharides that are processed to complex oligosaccharides before the laminin molecule is externalized by the cell. The rate-limiting step in the processing of the asparagine-linked glycans of laminin is at the point of action of alpha-mannosidase I since the principal laminin forms that accumulate in JAR cells contain Man9GlcNAc2 and Man8GlcNAc2 oligosaccharide units. The combination of subunits to form the disulfide-linked laminin molecule (Mr approximately 950,000) occurs rapidly within the cell at a time when the subunits contain these high mannose oligosaccharides. The production of laminin is limited by the availability of the A subunit such that excess B subunit forms accumulate intracellularly as uncombined B and a disulfide-linked B dimer. Pulse-chase kinetic studies establish these B forms as intermediates in the assembly of the laminin molecule. The fully assembled laminin undergoes further oligosaccharide processing and translocation to the cell surface, but uncombined B and B dimer are neither processed nor secreted to any significant extent. Therefore, laminin subunit combination appears to be a prerequisite for intracellular translocation, processing, and secretion. The mature laminin that contains complex oligosaccharides does not accumulate intracellularly but is rapidly externalized upon completion, either secreted into the culture medium (25%) or associated with the cell surface (75%) as determined by susceptibility to degradation by trypsin. About one-third of the laminin molecules secreted or shed by JAR cells into the chase medium contain a smaller A subunit form that appears to have been modified by limited proteolytic cleavage. The putative proteolytic event is closely timed to the release of the laminin into the culture medium.

Murine Ia-associated invariant chain's processing to complex oligosaccharide forms and its dissociation from the I-Ak complex.

PubMed

Holt, G D; Swiedler, S J; Freed, J H; Hart, G W

1985-07-01

The processing of murine invariant chain (Ii) to a cell surface form bearing complex N-linked oligosaccharides has been demonstrated in the B cell lymphoma, AKTB-1b. In addition, the rate of processing of pulse-labeled Ii has been determined relative to its rate of dissociation from the alpha/beta complex of I-Ak. Ii, alpha-, and beta-chains were immunoprecipitated with anti-I-Ak or anti-Ii monoclonal antibodies. The heretofore uncharacterized complex oligosaccharide form of Ii (Ii-c) was identified in gel-purified immunoprecipitates by peptide mapping with reverse-phase HPLC. Ii-c is resistant to deglycosylation by Endo H, which is specific for high-mannose N-linkages, but can be digested with Endo F, a glycosidase capable of cleaving both complex and high-mannose N-linked oligosaccharides. Immunoprecipitation of surface iodinated cells indicates that Ii-c is expressed on the plasma membrane. Pulse-chase metabolic labeling data show that the processing of Ii to Ii-c occurs with a t1/2 of about 120 min. In contrast, the processing of both alpha- and beta-chains of I-Ak to complex forms occurs with a t1/2 of 15 to 20 min. Our data show that Ii-hm begins to dissociate rapidly from the I-Ak complex after 100 to 120 min of chase. Only a small amount (less than 5% on a per mole basis) of Ii-c was found associated with the I-Ak complexes after 300 min of continuous metabolic labeling. These results are consistent with Ii serving as a carrier for Ia antigens as they are transported to the cell surface. In addition, they suggest that the processing of Ii to Ii-c, or a late processing event of the alpha- and beta-chains, such as their sialylation, may be a possible mechanism for inducing the dissociation of Ii from the I-Ak complex.

NuSTARUnveils a Compton-Thick Type 2 Quasar in MrK 34

DOE PAGES

Gandhi, P.; Lansbury, G. B.; Alexander, D. M.; ...

2014-08-22

We present Nuclear Spectroscopic Telescope Array ( NuSTAR) 3-40 keV observations of the optically selected Type 2 quasar (QSO2) SDSS J1034+6001 or Mrk 34. The high-quality hard X-ray spectrum and archival XMM- Newton data can be fitted self-consistently with a reflection-dominated continuum and a strong Fe Kα fluorescence line with equivalent width >1 keV. Prior X-ray spectral fitting below 10 keV showed the source to be consistent with being obscured by Compton-thin column densities of gas along the line of sight, despite evidence for much higher columns from multiwavelength data. NuSTAR now enables a direct measurement of this column andmore » shows that N H lies in the Compton-thick (CT) regime. The new data also show a high intrinsic 2-10 keV luminosity of L 2-10 ~ 10 44 erg s –1, in contrast to previous low-energy X-ray measurements where L 2-10 ≲ 10 43 erg s –1 (i.e., X-ray selection below 10 keV does not pick up this source as an intrinsically luminous obscured quasar). Both the obscuring column and the intrinsic power are about an order of magnitude (or more) larger than inferred from pre- NuSTAR X-ray spectral fitting. Mrk 34 is thus a "gold standard" CT QSO2 and is the nearest non-merging system in this class, in contrast to the other local CT quasar NGC 6240, which is currently undergoing a major merger coupled with strong star formation. For typical X-ray bolometric correction factors, the accretion luminosity of Mrk 34 is high enough to potentially power the total infrared luminosity. In conclusion, X-ray spectral fitting also shows that thermal emission related to star formation is unlikely to drive the observed bright soft component below ~3 keV, favoring photoionization instead.« less

Obscurity and Gender Resistance in Patricia Duncker's James Miranda Barry

PubMed Central

Funke, Jana

2012-01-01

Since his death in 1865, military surgeon James Barry has alternately been classified as a cross-dressing woman or as an intersexed individual. Patricia Duncker's novel James Miranda Barry (1999) poses an important challenge to such readings, as it does not reveal any foundational truth about Barry's sex. Resting on obscurity rather than revelation, the text frustrates the desire to know the past in terms of gender binaries and stable sexual identity categories. Drawing on feminist and queer theorisations of the relation between gender and time, this essay demonstrates that Duncker's use of obscurity opens up alternative strategies of gender resistance. PMID:25400502

49 CFR 392.33 - Obscured lamps or reflective devices/material.

Code of Federal Regulations, 2010 CFR

2010-10-01

... MOTOR CARRIER SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION FEDERAL MOTOR CARRIER SAFETY REGULATIONS DRIVING OF COMMERCIAL MOTOR VEHICLES Use of Lighted Lamps and Reflectors § 392.33 Obscured lamps or reflective devices/material. (a) No commercial motor vehicle shall be driven when any of the lamps...

Optically modulated fluorescence bioimaging: visualizing obscured fluorophores in high background.

PubMed

Hsiang, Jung-Cheng; Jablonski, Amy E; Dickson, Robert M

2014-05-20

Fluorescence microscopy and detection have become indispensible for understanding organization and dynamics in biological systems. Novel fluorophores with improved brightness, photostability, and biocompatibility continue to fuel further advances but often rely on having minimal background. The visualization of interactions in very high biological background, especially for proteins or bound complexes at very low copy numbers, remains a primary challenge. Instead of focusing on molecular brightness of fluorophores, we have adapted the principles of high-sensitivity absorption spectroscopy to improve the sensitivity and signal discrimination in fluorescence bioimaging. Utilizing very long wavelength transient absorptions of kinetically trapped dark states, we employ molecular modulation schemes that do not simultaneously modulate the background fluorescence. This improves the sensitivity and ease of implementation over high-energy photoswitch-based recovery schemes, as no internal dye reference or nanoparticle-based fluorophores are needed to separate the desired signals from background. In this Account, we describe the selection process for and identification of fluorophores that enable optically modulated fluorescence to decrease obscuring background. Differing from thermally stable photoswitches using higher-energy secondary lasers, coillumination at very low energies depopulates transient dark states, dynamically altering the fluorescence and giving characteristic modulation time scales for each modulatable emitter. This process is termed synchronously amplified fluorescence image recovery (SAFIRe) microscopy. By understanding and optically controlling the dye photophysics, we selectively modulate desired fluorophore signals independent of all autofluorescent background. This shifts the fluorescence of interest to unique detection frequencies with nearly shot-noise-limited detection, as no background signals are collected. Although the fluorescence brightness is improved slightly, SAFIRe yields up to 100-fold improved signal visibility by essentially removing obscuring, unmodulated background (Richards, C. I.; J. Am. Chem. Soc. 2009, 131, 4619). While SAFIRe exhibits a wide, linear dynamic range, we have demonstrated single-molecule signal recovery buried within 200 nM obscuring dye. In addition to enabling signal recovery through background reduction, each dye exhibits a characteristic modulation frequency indicative of its photophysical dynamics. Thus, these characteristic time scales offer opportunities not only to expand the dimensionality of fluorescence imaging by using dark-state lifetimes but also to distinguish the dynamics of subpopulations on the basis of photophysical versus diffusional time scales, even within modulatable populations. The continued development of modulation for signal recovery and observation of biological dynamics holds great promise for studying a range of transient biological phenomena in natural environments. Through the development of a wide range of fluorescent proteins, organic dyes, and inorganic emitters that exhibit significant dark-state populations under steady-state illumination, we can drastically expand the applicability of fluorescence imaging to probe lower-abundance complexes and their dynamics.

Sensitive radio survey of obscured quasar candidates

NASA Astrophysics Data System (ADS)

Alexandroff, Rachael M.; Zakamska, Nadia L.; van Velzen, Sjoert; Greene, Jenny E.; Strauss, Michael A.

2016-12-01

We study the radio properties of moderately obscured quasars in samples at both low (z ˜ 0.5) and high (z ˜ 2.5) redshift to understand the role of radio activity in accretion, using the Karl G. Jansky Very Large Array (VLA) at 6.0 GHz and 1.4 GHz. Our z ˜ 2.5 sample consists of optically selected obscured quasar candidates, all of which are radio-quiet, with typical radio luminosities of νLν[1.4 GHz] ≲ 1040 erg s-1. Only a single source is individually detected in our deep (rms˜10 μJy) exposures. This population would not be identified by radio-based selection methods used for distinguishing dusty star-forming galaxies and obscured active nuclei. In our pilot A-array study of z ˜ 0.5 radio-quiet quasars, we spatially resolve four of five objects on scales ˜5 kpc and find they have steep spectral indices with an average value of α = -0.75. Therefore, radio emission in these sources could be due to jet-driven or radiatively driven bubbles interacting with interstellar material on the scale of the host galaxy. Finally, we also study the additional population of ˜200 faint ( ˜ 40 μJy-40 mJy) field radio sources observed over ˜120 arcmin2 of our data. 60 per cent of these detections (excluding our original targets) are matched in the Sloan Digital Sky Survey (SDSS) and/or Wide-Field Infrared Survey Explorer (WISE) and are, in roughly equal shares, active galactic nuclei (AGN) at a broad range of redshifts, passive galaxies with no other signs of nuclear activity and infrared-bright but optically faint sources. Spectroscopically or photometrically confirmed star-forming galaxies constitute only a small minority of the matches. Such sensitive radio surveys allow us to address important questions of AGN evolution and evaluate the AGN contribution to the radio-quiet sky.

Fenestration obscuration techniques

NASA Astrophysics Data System (ADS)

Smalley, Michael

2007-10-01

There are situations where it is advantageous to visually obscure through glass, to an external observer, the movement of people within a well lit room. It may be that the building use has changed or existing measures which had provided obscuration such as 'Bomb-blast' curtains have been discontinued. Recognising that implemented solutions must create the minimum disruption to outward visibility and involve the least procedural effort (be simple to use), the Centre for Protection of National Infrastructure, CPNI, commissioned this study, defining key requirements including: (a) Automatic or simple manual operation (b) Obscuration of movement within the building from outside (c) Varying levels of obscuration depending on the difference in internal and external light levels. (d) Minimum disruption to outward visibility (e) Acceptable for use on heritage and iconic sites (f) Easy to retrofit (g) Low cost This report reviews earlier work carried out into the protection of Guardrooms by the use of lighting techniques coupled with the use of reflective and screen printed films. Other innovative solutions including Electrochromatic controllable glazing which may prove more appropriate to office and commercial buildings are also considered. It is seen that some measures, (window films or blinds), are cost effective and unsophisticated while more complex automatic systems using reactive glazing can offer critical design advantages. It must be noted however that some of the key requirements are mutually exclusive and any solution chosen will always be a compromise based on client needs and circumstances.

Mining the Infrared Sky for High-Redshift Quasars

NASA Astrophysics Data System (ADS)

Richards, Gordon

The Spitzer and WISE satellites have opened up new avenues for the study of active galactic nuclei (AGN) by peering through the dust shrouding half (or more) of AGNs. However, despite being more sensitive to shrouded AGNs, current selection methods being used in the mid-IR are still largely blind to the highest redshift quasars-both those that are shrouded and those that are not (and should therefore be easy to find). We describe projects to identify both unobscured (at z>3) and obscured quasars (at z>2) that have heretofore been missed in significant numbers. Finding the high-z obscured quasars in large numbers is crucial for fulfilling the legacy of NASA missions in the IR and X-ray. With these quasars we will be able to perform clustering analyses that break the degeneracy of models describing how black holes can ``feed back" energy to the large-scale host galaxy, significantly influencing its evolution. We will further trace the luminosity function of galaxies undergoing active accretion from low-luminosity AGNs to luminous quasars—probing the growth of the supermassive black holes that we see today in the local universe. Our new insights come about from leveraging new Spitzer data, primarily from the PI's SpitzerIRAC Equatorial Survey (SpIES). The Spitzer data are 2.5 magnitudes deeper than the "AllWISE" survey in a 125 square degree, multiwavelength-rich, equatorial region known as SDSS "Stripe 82". These data are crucial for extending mid-IR investigations to higher redshifts, both for unobscured and obscured sources. The PI's team are among the world's experts in using the proposed machine learning techniques to find both unobscured (type-1) and obscured (type- 2) quasars and in using quasar clustering and luminosity functions to do cutting-edge science. The luminosity function and clustering algorithms are already in place, allowing for timely completion of this project once the multi-wavelength NASA data have been incorporated. This project is directly relevant to our understanding of the evolution of galaxies and to NASA's goal of better understanding the Universe. Moreover, NASA's data archive is crucial to the project: it is only by using data from Spitzer and WISE that will allow us to more fully understand the physics of quasars—by probing them at epochs where they are both most difficult to find, but also the most influential.

Battlefield training in impaired visibility

NASA Astrophysics Data System (ADS)

Gammarino, Rudolph R.; Surhigh, James W.

1991-04-01

A laser training system entitled Shoot Through Obscuration MILES (STOM) is being developed to operate with Forward Looking InfraRed (FLIR) systems during battlefield exercises where visibility is impaired. The STOM system is capable of ranges in excess of 6 km and can penetrate battlefield obscurants such as fog-oil, smoke, dust, and rain.