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Sample records for chin ting-chuen pong

  1. Chin augmentation

    MedlinePlus

    ... chisel to make a second cut through the jaw bone. The jaw bone is moved and wired or screwed in ... see the final appearance of your chin and jaw for 3 to 4 months. Alternative Names Augmentation ...

  2. Éponges filantes

    NASA Astrophysics Data System (ADS)

    de Gennes, Pierre-Gilles

    Domingues Dos Santos et Ondarçuhu (1995) ont découvert les « gouttes filantes » contenant une solution de molécules réactives (chlorosilanes). Si une telle goutte est posée sur une surfae solide (verre, silice) comportant des groupes OH qui réagissent avec le silane, la goutte fuit les régions réagies de faible mouillabilité et se met en marche. Nous discutons ici le remplacement de la goutte par une « éponge » : particule de latex, ou caoutchouc, gonflée par le solvant. Deux cas sont envisagés : a) glissement d'une pastille donnant des vitesses 1 μm/s; b) roulement d'une sphère (donnant des vitesses comparables pour des particules de latex, mais plus élevées pour des sphères millimétriques de caoutchouc). Domingues Dos Santos and Ondarçuhu have discovered that certain droplets, containing a reactive solute (chlorosilane) move spontaneously on a glass surface. We discuss here the replacement of the drop by a "sponge": swollen latex or rubber particule. Two cases are considered: a) sliding of a flat sponge leading to velocities of order 1 μ/sec.; b) rolling of a sphere, giving comparable velocities for a latex particle, and larger velocities for millimetric rubber spheres.

  3. Chin augmentation - slideshow

    MedlinePlus

    ... anatomy URL of this page: //medlineplus.gov/ency/presentations/100009.htm Chin augmentation - series—Normal anatomy To use the sharing features on this page, please enable JavaScript. Go to slide 1 out of 5 Go to slide 2 ...

  4. Ping-pong auto-zero amplifier with glitch reduction

    DOEpatents

    Larson, Mark R.

    2008-01-22

    A ping-pong amplifier with reduced glitching is described. The ping-pong amplifier includes a nulling amplifier coupled to a switching network. The switching network is used to auto-zero a ping amplifier within a ping-pong amplifier. The nulling amplifier drives the output of a ping amplifier to a proper output voltage level during auto-zeroing of the ping amplifier. By being at a proper output voltage level, glitches associated with transitioning between a ping amplifier and a pong amplifier are reduced or eliminated.

  5. Chin force in violin playing.

    PubMed

    Obata, Satoshi; Kinoshita, Hiroshi

    2012-06-01

    Force generated between the left mandible of violinists and the chinrest of the violin was examined using a force-sensing chinrest developed in this study. A strain-gauge force sensor was built, and it was fixed between the violin's top plate and a chin cup. Fifteen professional/amateur violinists held the violin statically, played musical scales with different sound properties and sounding techniques, as well as an excerpt from a Max Bruch concerto. Peak and mean forces were evaluated for each task. In a separate experiment, lateral movement of the lower teeth due to different levels of voluntary chin force exertion was measured. Static holding forces observed were 15 and 22 N with and without the help of the left hand, respectively. Peak force increased from 16 N at soft dynamics to 20 N at strong dynamics during scales. The force further increased to 29 N with the use of vibrato technique and 35 N during shifts. Tempo and hand position did not affect the force. Playing a Bruch concerto induced a mean peak force of 52 N, ranging from 31 to 82 N among the violinists. The developed force-sensing chinrest could accurately record the generated chin force. Typical chin force to stabilize the violin during ordinary musical performance was less than 30 N, but it could momentarily exceed 50 N when technically demanding musical pieces were performed. The lateral shift of the mandible was fairly small (<0.4 mm) even with high chin-force exertion, possibly due to clenching of the molars.

  6. Launch Creativity with Ping-Pong Ball Challenge

    ERIC Educational Resources Information Center

    Kornoelje, Joanne; Roman, Harry T.

    2011-01-01

    Educators at Thomas A. Edison Middle School have worked together to bring invention information and activities to life. One activity in particular, Ping-Pong Ball Invention Challenge, has proven a great success. The Ping-Pong Ball Invention Challenge was inspired by the basic rules for PBS's "Design Squad"'s "Pop Fly" activity. In this article,…

  7. 21 CFR 878.3550 - Chin prosthesis.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Chin prosthesis. 878.3550 Section 878.3550 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES GENERAL AND PLASTIC SURGERY DEVICES Prosthetic Devices § 878.3550 Chin prosthesis....

  8. 21 CFR 878.3550 - Chin prosthesis.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Chin prosthesis. 878.3550 Section 878.3550 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES GENERAL AND PLASTIC SURGERY DEVICES Prosthetic Devices § 878.3550 Chin prosthesis....

  9. 21 CFR 878.3550 - Chin prosthesis.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Chin prosthesis. 878.3550 Section 878.3550 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES GENERAL AND PLASTIC SURGERY DEVICES Prosthetic Devices § 878.3550 Chin prosthesis....

  10. 21 CFR 878.3550 - Chin prosthesis.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Chin prosthesis. 878.3550 Section 878.3550 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES GENERAL AND PLASTIC SURGERY DEVICES Prosthetic Devices § 878.3550 Chin prosthesis....

  11. 21 CFR 878.3550 - Chin prosthesis.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Chin prosthesis. 878.3550 Section 878.3550 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES GENERAL AND PLASTIC SURGERY DEVICES Prosthetic Devices § 878.3550 Chin prosthesis....

  12. The physics of juggling a spinning ping-pong ball

    NASA Astrophysics Data System (ADS)

    Widenhorn, Ralf

    2016-12-01

    Juggling a spinning ball with a ping-pong paddle represents a challenge both in terms of hand-eye coordination and physics concepts. Here, we analyze the ping-pong ball's motion, and explore how the correct paddle angle relates to the ball's spin and speed, as it moves vertically up and down. For students, this requires engaging with concepts like momentum, angular momentum, free-body diagrams, and friction. The activities described in this article include high-speed video motion tracking of the ping-pong ball and the investigation of the frictional characteristics of the paddle. They can be done in a physics lab or at home, requiring only inexpensive or commonly used equipment, and can be undertaken by high school or college students.

  13. Big Hydrophobic Capillary Fluidics; Basically Water Ping Pong in Space

    NASA Astrophysics Data System (ADS)

    Weislogel, Mark; Attari, Babak; Wollman, Andrew; Cardin, Karl; Geile, John; Lindner, Thomas

    2016-11-01

    Capillary surfaces can be enormous in environments where the effects of gravity are small. In this presentation we review a number of interesting examples from demonstrative experiments performed in drop towers and aboard the International Space Station. The topic then focuses on large length scale hydrophobic phenomena including puddle jumping, spontaneous particle ejections, and large drop rebounds akin to water ping pong in space. Unseen footage of NASA Astronaut Scott Kelly playing water ping pong in space will be shown. Quantitative and qualitative results are offered to assist in the design of experiments for ongoing research. NASA NNX12A047A.

  14. Intelligent Management of Intelligence Agencies: Beyond Accountability Ping-Pong

    ERIC Educational Resources Information Center

    Tetlock, Philip E.; Mellers, Barbara A.

    2011-01-01

    The intelligence community (IC) is asked to predict outcomes that may often be inherently unpredictable--and is blamed for the inevitable forecasting failures, be they false positives or false negatives. To move beyond blame games of accountability ping-pong that incentivize bureaucratic symbolism over substantive reform, it is necessary to reach…

  15. Moment of Inertia of a Ping-Pong Ball

    ERIC Educational Resources Information Center

    Cao, Xian-Sheng

    2012-01-01

    This note describes how to theoretically calculate and experimentally measure the moment of inertia of a Ping-Pong[R] ball. The theoretical calculation results are in good agreement with the experimental measurements that can be reproduced in an introductory physics laboratory.

  16. Washington Commentary: Endless Ping-Pong over Math Education

    ERIC Educational Resources Information Center

    Lewis, Anne C.

    2005-01-01

    Ever since the charter school movement became big news, Anne C. Lewis has refrained from writing about it very much because it seemed more like covering each hit in a Ping-Pong game. As study and counter-study rolled off the presses and into the press releases, the substance became less and less relevant. Each new study was always sure to be…

  17. Improving security of the ping-pong protocol

    NASA Astrophysics Data System (ADS)

    Zawadzki, Piotr

    2013-01-01

    A security layer for the asymptotically secure ping-pong protocol is proposed and analyzed in the paper. The operation of the improvement exploits inevitable errors introduced by the eavesdropping in the control and message modes. Its role is similar to the privacy amplification algorithms known from the quantum key distribution schemes. Messages are processed in blocks which guarantees that an eavesdropper is faced with a computationally infeasible problem as long as the system parameters are within reasonable limits. The introduced additional information preprocessing does not require quantum memory registers and confidential communication is possible without prior key agreement or some shared secret.

  18. Biomechanical impact response of the human chin and manubrium.

    PubMed

    Stammen, Jason A; Bolte, John H; Shaw, Joshua

    2012-03-01

    Chin-to-chest impact commonly occurs in frontal crash simulations with restrained anthropomorphic test devices (ATDs) in non-airbag situations. This study investigated the biofidelity of this contact by evaluating the impact response of both the chin and manubrium of adult post-mortem human subjects (PMHSs). The adult PMHS data were scaled to a 10-year-old (YO) human size and then compared with the Hybrid III 10YO child (HIII-10C) ATD response with the same test configurations. For both the chin and manubrium, the responses of the scaled PMHS had different characteristics than the HIII-10C ATD responses. Elevated energy impact tests to the PMHS mandible provided a mean injury tolerance value for chin impact force. Chin contact forces in the HIII-10C ATD were calculated in previously conducted HYGE sled crash simulation tests, and these contact forces were strongly correlated with the Head Injury Criterion (HIC(36 ms)). The mean injurious force from the PMHS tests corresponded to a HIC(36 ms) value that would predict an elevated injury risk if it is assumed that fractures of the chin and skull are similarly correlated with HIC(36 ms). Given the rarity of same occupant-induced chin injury in booster-seated occupants in real crash data and the disparity in chin and manubrium stiffnesses between scaled PMHS and HIII-10C ATD, the data from this study can be made use of to improve biofidelity of chin-to-manubrium contact in ATDs.

  19. A Flipped Spoon and Chin Prompt to Increase Mouth Clean

    ERIC Educational Resources Information Center

    Dempsey, Jack; Piazza, Cathleen C.; Groff, Rebecca A.; Kozisek, Jennifer M.

    2011-01-01

    We treated the liquid refusal of a 15-month-old girl using 2 antecedent manipulations: flipped spoon and chin prompt. Use of the chin prompt in the absence of the flipped spoon failed to produce increases in mouth clean (a product measure of swallowing). By contrast, modest increases in mouth clean resulted from the implementation of the flipped…

  20. CHINs in the context of an evolving health care system.

    PubMed Central

    Duncan, K. A.

    1996-01-01

    Community Health Information Network (CHIN) developments have slowed, due to the chaotic change in the health care system and stakeholders' attendant short-sighted focus. CHINs are a long-term investment that is necessary for the health care system's evolution to maturity. Several arenas of essential CHIN activity are given that would be characteristic of a mature, goal-directed health care system Lack of enterprise-wide computer-based patient record systems is a major barrier. Even in the short term, however, trends and incentives exist that are likely to push stakeholders toward CHIN development. Some of these trends include changes in organizational structure and political pressures. Practical incentives include the need for stakeholder cooperation to achieve healthy communities, the prospects for telemedicine, and the demand for greater quality assurance. PMID:8947737

  1. Massive expanding hematoma of the chin following blunt trauma

    PubMed Central

    Niazi, K. Thanvir Mohamed; Raja, Dharmesh Kumar; Prakash, R.; Balaji, V. R.; Manikandan, D.; Ulaganathan, G.; Yoganandha, R.

    2016-01-01

    Posttraumatic hematoma of the face is common and usually self-limiting in nature. We report an unusual massive expanding hematoma of the chin within 9 h following a blunt trauma with no associated injuries or fracture. PMID:27829776

  2. Artificial "ping-pong" cascade of PIWI-interacting RNA in silkworm cells.

    PubMed

    Shoji, Keisuke; Suzuki, Yutaka; Sugano, Sumio; Shimada, Toru; Katsuma, Susumu

    2017-01-01

    PIWI-interacting RNAs (piRNAs) play essential roles in the defense system against selfish elements in animal germline cells by cooperating with PIWI proteins. A subset of piRNAs is predicted to be generated via the "ping-pong" cascade, which is mainly controlled by two different PIWI proteins. Here we established a cell-based artificial piRNA production system using a silkworm ovarian cultured cell line that is believed to possess a complete piRNA pathway. In addition, we took advantage of a unique silkworm sex-determining one-to-one ping-pong piRNA pair, which enabled us to precisely monitor the behavior of individual artificial piRNAs. With this novel strategy, we successfully generated artificial piRNAs against endogenous protein-coding genes via the expected back-and-forth traveling mechanism. Furthermore, we detected "primary" piRNAs from the upstream region of the artificial "ping-pong" site in the endogenous gene. This artificial piRNA production system experimentally confirms the existence of the "ping-pong" cascade of piRNAs. Also, this system will enable us to identify the factors involved in both, or each, of the "ping" and "pong" cascades and the sequence features that are required for efficient piRNA production.

  3. pong: fast analysis and visualization of latent clusters in population genetic data

    PubMed Central

    Behr, Aaron A.; Liu, Katherine Z.; Liu-Fang, Gracie; Nakka, Priyanka; Ramachandran, Sohini

    2016-01-01

    Motivation: A series of methods in population genetics use multilocus genotype data to assign individuals membership in latent clusters. These methods belong to a broad class of mixed-membership models, such as latent Dirichlet allocation used to analyze text corpora. Inference from mixed-membership models can produce different output matrices when repeatedly applied to the same inputs, and the number of latent clusters is a parameter that is often varied in the analysis pipeline. For these reasons, quantifying, visualizing, and annotating the output from mixed-membership models are bottlenecks for investigators across multiple disciplines from ecology to text data mining. Results: We introduce pong, a network-graphical approach for analyzing and visualizing membership in latent clusters with a native interactive D3.js visualization. pong leverages efficient algorithms for solving the Assignment Problem to dramatically reduce runtime while increasing accuracy compared with other methods that process output from mixed-membership models. We apply pong to 225 705 unlinked genome-wide single-nucleotide variants from 2426 unrelated individuals in the 1000 Genomes Project, and identify previously overlooked aspects of global human population structure. We show that pong outpaces current solutions by more than an order of magnitude in runtime while providing a customizable and interactive visualization of population structure that is more accurate than those produced by current tools. Availability and Implementation: pong is freely available and can be installed using the Python package management system pip. pong’s source code is available at https://github.com/abehr/pong. Contact: aaron_behr@alumni.brown.edu or sramachandran@brown.edu Supplementary Information: Supplementary data are available at Bioinformatics online. PMID:27283948

  4. The French Reader's Relationship to Poetry in the Electronic Age: Ponge, Alferi, and Vassiliou

    ERIC Educational Resources Information Center

    LeBlond-Schrader, Ellen Benton

    2010-01-01

    My dissertation investigates the twentieth and twenty-first century reader's relationship to poetic text as it is altered through daily exposure to technology in the rise of the information age, as seen in the works of Francis Ponge, Pierre Alferi and Veronique Vassiliou. My project also examines historical documents--radio and television…

  5. Taking a Swat at Physics with a Ping-Pong Paddle.

    ERIC Educational Resources Information Center

    Graney, Chris M.

    1994-01-01

    A professor of physics discusses ideas on how to use physics to improve your ping-pong game. Describes how basic physics was used to analyze a simple ball-paddle collision problem and provide students with insight on the application of physics to a fun and real life situation. (ZWH)

  6. Millisecond measurements without equipment: time of collision of a ping-pong ball with a table

    NASA Astrophysics Data System (ADS)

    Oladyshkin, Ivan V.; Oladyshkina, Anastasia A.

    2017-01-01

    We describe a simple experiment giving the opportunity to estimate the time of collision of a freely falling ping-pong ball and a table. The method is based on the ball deformation measurement and uses just elementary geometry and kinematics.

  7. Mechanisms of Airway Protection during Chin-Down Swallowing

    ERIC Educational Resources Information Center

    Macrae, Phoebe; Anderson, Cheryl; Humbert, Ianessa

    2014-01-01

    Purpose: This study examined the effects of chin-down swallowing on laryngeal vestibule closure. It also investigated the technique's rehabilitative impact, by assessing the stability of effects across multiple trials and aftereffects in neutral swallows on cessation of the technique. Method: Duration of laryngeal vestibule closure (dLVC) was…

  8. Ak-Chin Indian Community Biomass Feasiiblity Study

    SciTech Connect

    Mark A. Moser, RCM Digesters, Inc.; Mark Randall, Daystar Consulting, LLC; Leonard S. Gold, Ak-Chin Energy Services & Utility Strategies Consulting Group

    2005-12-31

    Study of the conversion of chicken litter to biogas for the production of energy. There was an additional requirement that after extracting the energy from the chicken litter the nutrient value of the raw chicken litter had to be returned to the Ak-Chin Farms for use as fertilizer in a form and delivery method acceptable to the Farm.

  9. Characteristics of Dry Chin-Tuck Swallowing Vibrations and Sounds

    PubMed Central

    Dudik, Joshua M; Jestrović, Iva; Luan, Bo; Coyle, James L.; Sejdić, Ervin

    2015-01-01

    Objective The effects of the chin-tuck maneuver, a technique commonly employed to compensate for dysphagia, on cervical auscultation are not fully understood. Characterizing a technique that is known to affect swallowing function is an important step on the way to developing a new instrumentation-based swallowing screening tool. Methods In this study, we recorded data from 55 adult participants who each completed five saliva swallows in a chin-tuck position. The resulting data was processed using previously designed filtering and segmentation algorithms. We then calculated 9 time, frequency, and time-frequency domain features for each independent signal. Results We found that multiple frequency and time domain features varied significantly between male and female subjects as well as between swallowing sounds and vibrations. However, our analysis showed that participant age did not play a significant role on the values of the extracted features. Finally, we found that various frequency features corresponding to swallowing vibrations did demonstrate statistically significant variation between the neutral and chin-tuck positions but sounds showed no changes between these two positions. Conclusion The chin-tuck maneuver affects many facets of swallowing vibrations and sounds and its effects can be monitored via cervical auscultation. Significance These results suggest that a subject’s swallowing technique does need to be accounted for when monitoring their performance with cervical auscultation based instrumentation. PMID:25974926

  10. Loss of l(3)mbt leads to acquisition of the ping-pong cycle in Drosophila ovarian somatic cells

    PubMed Central

    Sumiyoshi, Tetsutaro; Sato, Kaoru; Yamamoto, Hitomi; Iwasaki, Yuka W.; Siomi, Haruhiko; Siomi, Mikiko C.

    2016-01-01

    In Drosophila germ cells, PIWI-interacting RNAs (piRNAs) are amplified through a PIWI slicer-dependent feed-forward loop termed the ping-pong cycle, yielding secondary piRNAs. However, the detailed mechanism remains poorly understood, largely because an ex vivo model system amenable to biochemical analyses has not been available. Here, we show that CRISPR-mediated loss of function of lethal (3) malignant brain tumor [l(3)mbt] leads to ectopic activation of the germ-specific ping-pong cycle in ovarian somatic cells. Perinuclear foci resembling nuage, the ping-pong center, appeared following l(3)mbt mutation. This activation of the ping-pong machinery in cultured cells will greatly facilitate elucidation of the mechanism underlying secondary piRNA biogenesis in Drosophila. PMID:27474440

  11. Numb chin syndrome secondary to leptomeningeal carcinomatosis from gastric adenocarcinoma

    PubMed Central

    Riesgo, Vincent J.; Poveda, Julio; Rammohan, Kottil

    2015-01-01

    Numb chin syndrome (NCS) can be a sign of malignancy. Its association with gastric adenocarcinoma is rare. We report a case of a 27-year-old Hispanic female that presented with complaint of left sided headache associated with numbness of the left side of chin and lower gingiva. Initial brain MRI, whole body gallium scan, high resolution CT of chest and elevated protein in the CSF were suggestive of sarcoidosis. She was treated with IV steroids with transient clinical improvement. Two weeks later, her symptoms worsened and further evaluation revealed the diagnosis of a poorly differentiated metastatic gastric adenocarcinoma with leptomeningeal involvement. This case report aims to emphasize the importance of identifying NCS as a possible indication of an underlying malignant condition. Reported cases of NCS associated with metastatic gastric adenocarcinoma are very rare. PMID:25830044

  12. Choosing the Best Procedure to Augment the Chin: Is Anything Better than an Implant?

    PubMed

    Sykes, Jonathan M; Fitzgerald, Rebecca

    2016-10-01

    The chin plays a very important role in overall facial appearance, and aesthetic procedures to augment the chin in patients with microgenia can improve overall facial balance. Many procedures exist to enhance the appearance of a small chin. Procedures include surgeries such as placement of an alloplast implant and bony osteotomy of the mentum (sliding genioplasty). The advantages and disadvantages of each surgical technique are well documented. Although surgical augmentation of the chin has been the gold standard of therapy, recent development of injectable filler products with lifting capacity has changed the way that many practitioners alter chin shape and size. Filler agents allow augmentation of the chin in horizontal (projection), vertical, and transverse dimensions. Injectable fillers are a simple, noninvasive procedure that causes minimal to no downtime, incurs minimal risks, and allows the practitioner to shape the chin in three dimensions. This procedure allows patients to enhance their chin size without requiring an operative visit. As more and varied filler products become FDA-approved, the versatility and application of these agents will increase.

  13. What is the chin-down posture? A questionnaire survey of speech language pathologists in Japan and the United States.

    PubMed

    Okada, Sumiko; Saitoh, Eiichi; Palmer, Jeffrey B; Matsuo, Koichiro; Yokoyama, Michio; Shigeta, Ritsuko; Baba, Mikoto

    2007-07-01

    The "chin-down" or "chin-tuck" maneuver is a postural technique widely used in dysphagia treatment. The posture, however, does not have a precise anatomical definition. We studied the current practice of 42 speech-language pathologists (SLPs) in Japan and the U.S. with a questionnaire survey regarding the chin-down posture. The main findings were that (1) three of five of the pictures were selected by respondents both in Japan and in the U.S. as depicting the chin-down posture; (2) 23% of Japanese and 58% of the U.S. SLPs made a distinction between chin down and chin tuck; and (3) the use of anatomical terminology by SLPs differed between the two countries. This study showed that there is poor agreement among SLPs about the meaning of the chin-down and chin-tuck postures. Developing a precise definition is important because various postures may have differing physiologic effects.

  14. “Ping-pong gaze” secondary to monoamine oxidase inhibitor overdose

    PubMed Central

    Attaway, Amy; Sroujieh, Laila; Mersfelder, Tracey L.; Butler, Christopher; Ouellette, Daniel

    2016-01-01

    An infrequent manifestation of monoamine oxidase inhibitor (MAOI) toxicity is “ping-pong gaze” (PPG). We describe the case of a 26-year-old female who was found unresponsive after taking 40 tablets of phenelzine. On presentation to the hospital, her eyes were moving in characteristic “ping pong” fashion. After 6 hours her gaze terminated. The following day her neurologic exam was benign and she had no long-term sequelae. While the etiology of PPG is unknown, it is most often seen with irreversible structural brain damage. However, a detailed literature review revealed that previous cases of MAOI toxicity where the patient survived have all had complete neurologic recovery. PMID:27127395

  15. Kinematic and electromyographic comparisons between chin-ups and lat-pull down exercises.

    PubMed

    Doma, Kenji; Deakin, Glen B; Ness, Kevin F

    2013-09-01

    The purpose of this study was to compare kinematics and muscle activity between chin-ups and lat-pull down exercises and between muscle groups during the two exercises. Normalized electromyography (EMG) of biceps brachii (BB), triceps brachii (TB), pectoralis major (PM), latissimus dorsi (LD), rectus abdominus (RA), and erector spinae (ES) and kinematics of back, shoulder, and seventh cervical vertebrae (C7) was analysed during chin-ups and lat-pull down exercises. Normalized EMG of BB and ES and kinematics of shoulder and C7 for chin-ups were greater than lat-pull down exercises during the concentric phase (p < 0.05). For the eccentric phase, RA during lat-pull down exercises was greater than chin-ups and the kinematics of C7 during chin-ups was greater than lat-pull down exercises (p < 0.05). For chin-ups, BB, LD, and ES were greater than PM during the concentric phase, whereas BB and LD were greater than TB, and LD was greater than RA during the eccentric phase (p < 0.05). For lat-pull down exercise, BB and LD were greater than PM, TB, and ES during the concentric phase, whereas LD was greater than PM, TB, and BB during the eccentric phase (p < 0.05). Subsequently, chin-ups appears to be a more functional exercise.

  16. Static test of a fan-powered chin nozzle for V/STOl applications

    NASA Technical Reports Server (NTRS)

    Salemann, V.

    1981-01-01

    The performance of a "chin" nozzle which diverts flow in a downward direction immediately downstream of a fan typical of designs suitable for V/STOL A applications was evaluated. Back pressure distortion to the fan and fan discharge pressure distortion were also measured. Results show that the distortion is significant at the closest spacing between the fan exit and cascade entrance tested, and that the chin nozzle performance deteriorates with increased flow diversion to the chin nozzle. Color oil flow visualization on video tape and still photos were also obtained. Tests were conducted behind a 12" model fan in the NASA-Lewis fan calibration facility.

  17. Combined treatment with botulinum toxin and hyaluronic acid to correct unsightly lateral-chin depression*

    PubMed Central

    Braz, André Vieira; Louvain, Dailana; Mukamal, Luana Vieira

    2013-01-01

    With aging, anatomical changes are observed in the face. In the lower third, these changes are expressed as ptosis of the angle of the mouth, lip enhancement groove mentalis; decrease in concavity between the jaw and neck and very noticeable platysmal banding. The repeated contraction of muscles of the lateral-chin together with the band platysmal side form what are called a marionette groove. Treating the whole lateral-chin area can result in a more harmonious aspect of the face when compared with treatment of a marionette groove in isolation. In this paper we describe combined treatment of the lateral chin area using botulinum toxin and fillers. PMID:23539022

  18. Chin prompt plus re-presentation as treatment for expulsion in children with feeding disorders.

    PubMed

    Wilkins, Jonathan W; Piazza, Cathleen C; Groff, Rebecca A; Vaz, Petula C M

    2011-01-01

    Expulsion (spitting out food) is a problem behavior observed in many children with feeding disorders. In the current investigation, we identified 4 children diagnosed with a feeding disorder who exhibited high rates of expulsion. Treatment with re-presentation (placing expelled liquids or solids back into the child's mouth) was not effective in reducing expulsion. Therefore, we added a chin-prompt procedure (the feeder applied gentle upward pressure to the child's chin and lower lip) for the initial presentation and the re-presentation. Chin prompt plus re-presentation resulted in low rates of expulsion for all 4 children. The results are discussed in terms of the potential underlying mechanisms behind the effectiveness of the chin-prompt procedure.

  19. Kinetics of Spanish broom peroxidase obeys a Ping-Pong Bi-Bi mechanism with competitive inhibition by substrates.

    PubMed

    Pérez Galende, Patricia; Hidalgo Cuadrado, Nazaret; Kostetsky, Eduard Ya; Roig, Manuel G; Villar, Enrique; Shnyrov, Valery L; Kennedy, John F

    2015-11-01

    In plants, adverse conditions often induce an increase in reactive oxygen species (ROS) such as hydrogen peroxide (H2O2). H2O2 is reduced to water, and thus becomes detoxified by enzymes such as Cytisus multiflorus peroxidase (CMP). Here, the steady-state kinetics of the H2O2-supported oxidation of different organic substrates by CMP was investigated. Analysis of the initial rates vs. H2O2 and reducing substrate concentrations proved to be consistent with a substrate-inhibited Ping-Pong Bi-Bi reaction mechanism. The phenomenological approach expresses the peroxidase Ping-Pong mechanism in the form of the Michaelis-Menten equation and affords an interpretation of the effects in terms of the kinetic parameters [Formula: see text] , [Formula: see text] , kcat, [Formula: see text] , [Formula: see text] and of the microscopic rate constants, k1 and k3, of the shared three-step catalytic cycle of peroxidases.

  20. Follicular keratosis of the chin treated with 1.24R-dihydroxyvitamin D3 ointment.

    PubMed

    Yanagihara, Makoto; Takeda, Kiminobu; Tanabe, Hiroshi; Abe, Shinya; Ishizaki, Hiroshi

    2007-01-01

    In follicular keratosis of the chin, keratotic follicular papules occur on the chin and jaw due to localized prolonged pressure and friction on the naked skin. We present one patient with this disorder. The dermatoscopic examination revealed many well-demarcated yellow spindle bodies in the patchy lesion. Therapy with 1.24R-dihydroxyvitamin D3 ointment was effective during the treatment but had no residual positive effect.

  1. Short faces, big tongues: developmental origin of the human chin.

    PubMed

    Coquerelle, Michael; Prados-Frutos, Juan Carlos; Rojo, Rosa; Mitteroecker, Philipp; Bastir, Markus

    2013-01-01

    During the course of human evolution, the retraction of the face underneath the braincase, and closer to the cervical column, has reduced the horizontal dimension of the vocal tract. By contrast, the relative size of the tongue has not been reduced, implying a rearrangement of the space at the back of the vocal tract to allow breathing and swallowing. This may have left a morphological signature such as a chin (mental prominence) that can potentially be interpreted in Homo. Long considered an autopomorphic trait of Homo sapiens, various extinct hominins show different forms of mental prominence. These features may be the evolutionary by-product of equivalent developmental constraints correlated with an enlarged tongue. In order to investigate developmental mechanisms related to this hypothesis, we compare modern 34 human infants against 8 chimpanzee fetuses, whom development of the mandibular symphysis passes through similar stages. The study sets out to test that the shared ontogenetic shape changes of the symphysis observed in both species are driven by the same factor--space restriction at the back of the vocal tract and the associated arrangement of the tongue and hyoid bone. We apply geometric morphometric methods to extensive three-dimensional anatomical landmarks and semilandmarks configuration, capturing the geometry of the cervico-craniofacial complex including the hyoid bone, tongue muscle and the mandible. We demonstrate that in both species, the forward displacement of the mental region derives from the arrangement of the tongue and hyoid bone, in order to cope with the relative horizontal narrowing of the oral cavity. Because humans and chimpanzees share this pattern of developmental integration, the different forms of mental prominence seen in some extinct hominids likely originate from equivalent ontogenetic constraints. Variations in this process could account for similar morphologies.

  2. Synergistic "ping-pong" energy transfer for efficient light activation in a chromophore-catalyst dyad.

    PubMed

    Quaranta, Annamaria; Charalambidis, Georgios; Herrero, Christian; Margiola, Sofia; Leibl, Winfried; Coutsolelos, Athanassios; Aukauloo, Ally

    2015-10-07

    The synthesis of a porphyrin-Ru(II) polypyridine complex where the porphyrin acts as a photoactive unit and the Ru(II) polypyridine as a catalytic precursor is described. Comparatively, the free base porphyrin was found to outperform the ruthenium based chromophore in the yield of light induced electron transfer. Mechanistic insights indicate the occurrence of a ping-pong energy transfer from the (1)LC excited state of the porphyrin chromophore to the (3)MCLT state of the catalyst and back to the (3)LC excited state of the porphyrin unit. The latter, triplet-triplet energy transfer back to the chromophore, efficiently competes with fast radiationless deactivation of the excited state at the catalyst site. The energy thus recovered by the chromophore allows improved yield of formation of the oxidized form of the chromophore and concomitantly of the oxidation of the catalytic unit by intramolecular charge transfer. The presented results are among the rare examples where a porphyrin chromophore is successfully used to drive an oxidative activation process where reductive processes prevail in the literature.

  3. An improved control mode for the ping-pong protocol operation in imperfect quantum channels

    NASA Astrophysics Data System (ADS)

    Zawadzki, Piotr

    2015-07-01

    Quantum direct communication (QDC) can bring confidentiality of sensitive information without any encryption. A ping-pong protocol, a well-known example of entanglement-based QDC, offers asymptotic security in a perfect quantum channel. However, it has been shown (Wójcik in Phys Rev Lett 90(15):157901, 2003. doi:10.1103/PhysRevLett.90.157901) that it is not secure in the presence of losses. Moreover, legitimate parities cannot rely on dense information coding due to possible undetectable eavesdropping even in the perfect setting (Pavičić in Phys Rev A 87(4):042326, 2013. doi:10.1103/PhysRevA.87.042326). We have identified the source of the above-mentioned weaknesses in the incomplete check of the EPR pair coherence. We propose an improved version of the control mode, and we discuss its relation to the already-known attacks that undermine the QDC security. It follows that the new control mode detects these attacks with high probability and independently on a quantum channel type. As a result, an asymptotic security of the QDC communication can be maintained for imperfect quantum channels, also in the regime of dense information coding.

  4. Tongue contractions during speech may have led to the development of the bony geometry of the chin following the evolution of human language: a mechanobiological hypothesis for the development of the human chin.

    PubMed

    Ichim, Ionut; Kieser, Jules; Swain, Michael

    2007-01-01

    One of the most fundamental yet unanswered questions of human evolution is that of the development of the chin. Whereas it is known that the chin, or mentum osseum, is an unique anatomical feature of modern humans that emerged during the Middle and Late Pleistocene, its origin and biomechanical significance are the subjects of intense controversy. Theories range from the suggestion that the chin evolved as a result of progressive reduction of the dental arch, which left it as a protrusion, to the hypothesis that it provided resistance to mandibular bending during mastication. Until now however, no accepted functional explanation of the human chin has emerged. Here, we develop the hypothesis that the actions of the tongue and non-masticatory orofacial muscles may have played a significant role on the development of the human chin. We report numerical simulations of the forces and resultant stresses developed in hypothetical chinned and non-chinned mandibles. Using empirical data and estimates of the forces generated by the human tongue during speech, our hypothesis suggests that the chin might in fact have developed as a result of the actions of the tongue and perioral muscles, rather than as a buttress to withstand masticatory induced stress. This provides a new perspective on the generation of the chin and importantly, suggests that its appearance may be causally related to the development of the human language.

  5. piRNA biogenesis during adult spermatogenesis in mice is independent of the ping-pong mechanism

    PubMed Central

    Beyret, Ergin; Liu, Na; Lin, Haifan

    2012-01-01

    piRNAs, a class of small non-coding RNAs associated with PIWI proteins, have broad functions in germline development, transposon silencing, and epigenetic regulation. In diverse organisms, a subset of piRNAs derived from repeat sequences are produced via the interplay between two PIWI proteins. This mechanism, termed “ping-pong” cycle, operates among the PIWI proteins of the primordial mouse testis; however, its involvement in postnatal testes remains elusive. Here we show that adult testicular piRNAs are produced independent of the ping-pong mechanism. We identified and characterized large populations of piRNAs in the adult and postnatal developing testes associated with MILI and MIWI, the only PIWI proteins detectable in these testes. No interaction between MILI and MIWI or sequence feature for the ping-pong mechanism among their piRNAs was detected in the adult testis. The majority of MILI- and MIWI-associated piRNAs originate from the same DNA strands within the same loci. Both populations of piRNAs are biased for 5′ Uracil but not for Adenine on the 10th nucleotide position, and display no complementarity. Furthermore, in Miwi mutants, MILI-associated piRNAs are not downregulated, but instead upregulated. These results indicate that the adult testicular piRNAs are predominantly, if not exclusively, produced by a primary processing mechanism instead of the ping-pong mechanism. In this primary pathway, biogenesis of MILI- and MIWI-associated piRNAs may compete for the same precursors; the types of piRNAs produced tend to be non-selectively dictated by the available precursors in the cell; and precursors with introns tend to be spliced before processed into piRNAs. PMID:22907665

  6. Reconstruction of the chin using an expanded deltopectoral flap following multiple recurrences of oral cancer

    PubMed Central

    Balakrishnan, Chenicheri; Hackenson, David; Balakrishnan, Anila; Elliott, David; Careaga, Daniel

    2012-01-01

    An important alternative to free tissue transfer in patients requiring correction of soft tissue chin defects are local and regional flaps, such as the pectoralis major myocutaneous flap and deltopectoral flap. With predictable vascular supply, potential for large size, and good aesthetic match for facial and cervical skin, the deltopectoral flap can offer the reconstructive surgeon additional options in patients who lack vessels suitable for free tissue transfer. The use of an expanded deltopectoral flap for a staged reconstruction of the chin in a patient with cancer recurrences, concomitant resections, radiation and multiple reconstructions is reported. PMID:23997595

  7. Method of induction could affect emotional outcomes: comment on markey, chin, vanepps, and loewenstein (2014 ).

    PubMed

    Bench, Shane W; Yaugher, Ashley C; Lench, Heather C

    2015-04-01

    Markey, Chin, Vanepps, and Loewenstein (2014) demonstrated six methods for the induction of boredom. However, a clear and testable definition of boredom should be established prior to experimental manipulation of the construct. Defining boredom from a functional emotion perspective is one approach that affords a definition separable from the outcomes associated with boredom and insight into which manipulations may effectively target the construct.

  8. Videomanometric analysis of supraglottic swallow, effortful swallow, and chin tuck in healthy volunteers.

    PubMed

    Bülow, M; Olsson, R; Ekberg, O

    1999-01-01

    Simultaneous videoradiography and solid-state manometry (videomanometry) was applied in eight healthy volunteers (four women, four men; age range 25-64 years, mean age 41 years) without swallowing problems. Three different swallowing techniques were tested; supraglottic swallow, effortful swallow, and chin tuck. Seven videoradiographic variables and six manometric variables were analyzed. The supraglottic swallowing technique did not differ significantly from that of the control swallows. The effortful swallow had a significantly (p = 0.0001) reduced hyoid-mandibular distance preswallow due to an elevation of the hyoid and the larynx, which caused a significantly (p = 0.007) reduced maximal hyoid movement and a significantly (p = 0.009) reduced laryngeal elevation during swallow. The chin tuck swallow had a significantly (p = 0. 001) reduced laryngohyoid distance and also a significantly (p = 0. 004) reduced hyoid-mandibular distance. The chin tuck swallow also displayed significantly (p = 0.003) weaker pharyngeal contractions. Videomanometry allows for analysis of bolus transport, movement of anatomical structures, and measurement of intraluminal pressures. These variables are important when evaluating swallowing techniques. In the present study, we made a few observations that never have been reported before. When healthy volunteers performed supraglottic swallow, they performed the technique somewhat differently. Therefore, we assume dysphagic patients would need a substantial period of training to perform a technique efficiently. Chin tuck could impair protection of the airways in dysphagic patients with weak pharyngeal constrictor muscles.

  9. Papular Acne Scars of the Nose and Chin: An Under-recognised Variant of Acne Scarring

    PubMed Central

    Ali, Faisal R; Kirk, Michael; Madan, Vishal

    2016-01-01

    Background: Scarring following acne vulgaris is common and can be of profound psychosocial consequence. Aims and Objectives: We have clinically noted a variant of acne scarring, overlooked by previous categorisation schemes, which we have denominated as papular acne scars of the nose and chin. We sought to characterise these novel entities further. Materials and Methods: Initially, we identified 14 patients with papular acne scars of the nose and chin in a cosmetic dermatology clinic, of whom two were female and rest were male. We then prospectively evaluated 100 consecutive patients attending our tertiary referral acne isotretinoin clinic and 49 patients attending a general dermatology clinic. Results: Amongst 149 patients, from a general dermatology and tertiary acne clinic, soft papular scars were noted in four patients, distributed on the nose and chin. Three of the four patients were male, three patients had additional acne scars and the median age was 23.5. Conclusions: We have identified 18 patients with papular acne scars of the nose and chin and propose that this new category should be added to acne scarring classification schemes. Future work should be directed at corroborating the epidemiology of such lesions and describing effective treatment modalities. PMID:28163455

  10. Seismic detections of the 15 February 2013 Chelyabinsk meteor from the dense ChinArray

    NASA Astrophysics Data System (ADS)

    Li, Lu; Wang, Baoshan; Peng, Zhigang; Wang, Weitao

    2016-08-01

    ChinArray is a dense portable broadband seismic network to cover the entire continental China, and the Phase I is deployed along the north-south seismic belt in southwest China. In this study, we analyze seismic data recorded on the ChinArray following the February 15, 2013 Chelyabinsk (Russia) meteor. This was the largest known object entering the Earth's atmosphere since the 1908 Tunguska meteor. The seismic energy radiated from this event was recorded by seismic stations worldwide including the dense ChinArray that are more than 4000 km away. The weak signal from the meteor event was contaminated by a magnitude 5.8 Tonga earthquake occurred ~20 min earlier. To test the feasibility of detecting the weak seismic signals from the meteor event, we compute vespagram and perform F-K analysis to the surface-wave data. We identify a seismic phase with back azimuth (BAZ) of 329.7° and slowness of 34.73 s/deg, corresponding to the surface wave from the Russian meteor event (BAZ ~325.97°). The surface magnitude ( M S) of the meteor event is 3.94 ± 0.18. We also perform similar analysis on the data from the broadband array F-net in Japan, and find the BAZ of the surface waves to be 316.61°. With the different BAZs of ChinArray and F-net, we locate the Russian meteor event at 58.80°N, 58.72°E. The relatively large mislocation (~438 km as compared with 55.15°N, 61.41°E by others) may be a result of the bending propagation path of surface waves, which deviates from the great circle path. Our results suggest that the dense ChinArray and its subarrays could be used to detect weak signals at teleseismic distances.

  11. PIF- and Pong-like transposable elements: distribution, evolution and relationship with Tourist-like miniature inverted-repeat transposable elements.

    PubMed Central

    Zhang, Xiaoyu; Jiang, Ning; Feschotte, Cédric; Wessler, Susan R

    2004-01-01

    Miniature inverted-repeat transposable elements (MITEs) are short, nonautonomous DNA elements that are widespread and abundant in plant genomes. Most of the hundreds of thousands of MITEs identified to date have been divided into two major groups on the basis of shared structural and sequence characteristics: Tourist-like and Stowaway-like. Since MITEs have no coding capacity, they must rely on transposases encoded by other elements. Two active transposons, the maize P Instability Factor (PIF) and the rice Pong element, have recently been implicated as sources of transposase for Tourist-like MITEs. Here we report that PIF- and Pong-like elements are widespread, diverse, and abundant in eukaryotes with hundreds of element-associated transposases found in a variety of plant, animal, and fungal genomes. The availability of virtually the entire rice genome sequence facilitated the identification of all the PIF/Pong-like elements in this organism and permitted a comprehensive analysis of their relationship with Tourist-like MITEs. Taken together, our results indicate that PIF and Pong are founding members of a large eukaryotic transposon superfamily and that members of this superfamily are responsible for the origin and amplification of Tourist-like MITEs. PMID:15020481

  12. Fiddler's neck: Chin rest-associated irritant contact dermatitis and allergic contact dermatitis in a violin player.

    PubMed

    Caero, Jennifer E; Cohen, Philip R

    2012-09-15

    Fiddler's neck refers to an irritant contact dermatitis on the submandibular neck of violin and viola players and an allergic contact dermatitis to nickel from the bracket attaching the violin to the chin rest on the violinist's supraclavicular neck. A 26-year-old woman developed submandibular and supraclavicular left neck lesions corresponding to the locations of the chin rest and bracket that was attached to her violin that held it against her neck when she played. Substitution of a composite chin rest, which did not contain nickel, and the short-term application of a low potency topical corticosteroid cream, resulted in complete resolution of the allergic contact dermatitis supraclavicular neck lesion. The irritant contact dermatitis submandibular neck lesion persisted. In conclusion, violin players are predisposed to developing irritant contact dermatitis or allergic contact dermatitis from the chin rest. We respectfully suggest that the submandibular neck lesions from contact with the chin rest be referred to as 'fiddler's neck - type 1,' whereas the supraclavicular neck lesions resulting from contact of the bracket holding the chin rest in place be called 'fiddler's neck - type 2.' A composite chin rest should be considered in patients with a preceding history of allergic contact dermatitis to nickel.

  13. Bone resorption under chin implants: The orthodontist's role in its diagnosis and management.

    PubMed

    Polo, Mario

    2017-01-01

    Alloplastic chin implants have been a valuable treatment modality for the correction of microgenia. Their use has provided satisfactory esthetic results by improving facial balance. However, bone resorption under these implants can occur. Case reports of 4 patients with the incidental radiographic finding of the presence of chin implants are presented. All 4 subjects had lateral cephalograms and panoramic x-rays taken as part of their orthodontic evaluation. One had a normal mandibular symphyseal contour, and 3 had bone resorption under the implants. One subject had severe resorption. In addition to panoramic and cephalometric x-rays, the subject with severe resorption also had magnetic resonance imaging and computerized tomography as part of the evaluation workup.

  14. Fitting the CHIN (community health information network) to the customer: three case studies.

    PubMed

    Rabunski, J S; Weil, J P

    1995-01-01

    Each of the case studies described above is typical of many health care organizations in the northeastern United States. The reasons each of these three organizations seeks to form or participate in a CHIN varies-from establishing the loyalty of practicing physicians in a community hospital's struggle to survive, through sharing of real-time patient care data in a successful community-wide effort to avoid expensive duplication of services, to driving the transition from a multihospital integrated delivery system to a full-risk accountable health plan. While the need to reduce costs, by taking advantage of economies of scale and prospectively monitoring utilization, is common to all three organizations, selecting the type of CHIN that best fits each scenario, with particular emphasis on aspects of control, is the key success factor.

  15. Ping-pong amplification of a retroviral vector achieves high-level gene expression: human growth hormone production.

    PubMed Central

    Kozak, S L; Kabat, D

    1990-01-01

    Retroviral vectors offer major advantages for gene transfer studies but have not been useful for producing proteins in large quantities. This deficiency has resulted in part from interference to superinfection, which limits the numbers of active proviruses in cells. Recently, we found that these vectors amplify when they are added as calcium phosphate precipitates to cocultures of cells that package retroviruses into ecotropic and amphotropic host range envelopes. Helper-free virions from either cell type can infect the other without interference, resulting in theoretically limitless back-and-forth (ping-pong) vector replication. In initial studies, however, amplifications of a vector that contained the human growth hormone gene ceased when the hormone produced was 0.3% or less of cellular protein synthesis. This limit was caused by two factors. First, recombinant shutoff viruses that are replication defective and encode envelope glycoproteins form at a low probability during any round of the vector replication cycle and these spread in cocultures, thereby establishing interference. Single cells in shutoff cocultures therefore synthesize both ecotropic and amphotropic envelope glycoproteins, and they release promiscuous (presumably hybrid) virions. The probability of forming shutoff viruses before the vector had amplified to a high multiplicity was reduced by using small cocultures. Second, cells with large numbers of proviruses are unhealthy and their proviral expression can be unstable. Stable expresser cell clones were obtained by selection. Thereby, cell lines were readily obtained that stably produce human growth hormone as 4 to 6% of the total protein synthesis. A ping-pong retroviral vector can be used for high-level protein production in vertebrate cells. Images PMID:2352330

  16. The Effect of Chin-cup Therapy in Class III Malocclusion: A Systematic Review

    PubMed Central

    Mousoulea, Sophia; Tsolakis, Ioannis; Ferdianakis, Efstratios; Tsolakis, Apostolos I.

    2016-01-01

    Background: The treatment of Class III malocclusion has been challenging for orthodontists. Among a plethora of treatment modalities, the chin-cup is considered a traditional appliance for early orthopedic intervention. Objective: The present study aims to investigate the current scientific evidence regarding the effectiveness of chin-cup therapy in Class III malocclusion of prognathic growing patients. Method: A systematic review of the literature was conducted using PubMed/Medline and the Cochrane Central Register of Controlled Trials from January 1954 to October 2015. Articles were selected based on established inclusion/ exclusion criteria. Results: The search strategy resulted in 3285 articles.14 studies were selected for the final analysis. They were all CCTs, 13 of retrospective and 1 of prospective design. Methodological quality was evaluated by a risk of bias assessment, as suggested by the Cochrane Risk of Bias Assessment Tool for Non-Randomized Studies on Interventions. The reported evidence presented favorable short-term outcomes both in hard and soft tissues improving the Class III profile, as well as desirable dento-alveolar changes, positively affecting the Class III malocclusion. Conclusion: There is considerable agreement between studies that chin-cup therapy can be considered for the short-term treatment of growing patients with Class III malocclusion, as indicated by favorable changes both in the hard and soft tissues. The existence of considerable risk of bias in all selected studies and the unclear long-term effectiveness of chin-cup therapy highlight the need for further investigation to draw reliable conclusions. PMID:28077971

  17. Geographic variation in chin shape challenges the universal facial attractiveness hypothesis.

    PubMed

    Thayer, Zaneta M; Dobson, Seth D

    2013-01-01

    The universal facial attractiveness (UFA) hypothesis proposes that some facial features are universally preferred because they are reliable signals of mate quality. The primary evidence for this hypothesis comes from cross-cultural studies of perceived attractiveness. However, these studies do not directly address patterns of morphological variation at the population level. An unanswered question is therefore: Are universally preferred facial phenotypes geographically invariant, as the UFA hypothesis implies? The purpose of our study is to evaluate this often overlooked aspect of the UFA hypothesis by examining patterns of geographic variation in chin shape. We collected symphyseal outlines from 180 recent human mandibles (90 male, 90 female) representing nine geographic regions. Elliptical Fourier functions analysis was used to quantify chin shape, and principle components analysis was used to compute shape descriptors. In contrast to the expectations of the UFA hypothesis, we found significant geographic differences in male and female chin shape. These findings are consistent with region-specific sexual selection and/or random genetic drift, but not universal sexual selection. We recommend that future studies of facial attractiveness take into consideration patterns of morphological variation within and between diverse human populations.

  18. Force transmission to the mandible by chin straps during head impacts in football.

    PubMed

    Rowson, Steven; McNeely, David E; Duma, Stefan M

    2008-01-01

    The objective of this study was to determine the force transmitted to the mandible from the chin strap in football helmets for head impacts. A total of 32 tests were performed comparing front and side impact locations. Each location was tested at two impact velocities (6.5 m/s and 9.0 m/s). Different combinations of neck collars and shoulder pads were tested at each speed and location to account for potential equipment variability between football players. A 50th percentile male Hybrid III dummy was equipped with a helmet, shoulder pads, and various neck collars. Tension load cells were installed on the left and right sides of the chin straps. From the tension values in the chin strap, the force transmitted to the mandible was calculated. With the front impact location, the average peak mandible load was 568 +/- 80 N at 6.5 m/s and 806 +/- 64 N at 9.0 m/s. With the side impact location, the average peak mandible load was 87 +/- 36 N at 6.5 m/s and 170 +/- 80 N at 9.0 m/s. Although there are some overlying assumptions, these values represent a good estimation of the forces acting on the mandible for head impacts in football.

  19. Directional scattering from the glossy flower of Ranunculus: how the buttercup lights up your chin.

    PubMed

    Vignolini, Silvia; Thomas, Meredith M; Kolle, Mathias; Wenzel, Tobias; Rowland, Alice; Rudall, Paula J; Baumberg, Jeremy J; Glover, Beverley J; Steiner, Ullrich

    2012-06-07

    The bright and glossy appearance of the flowers of Ranunculus repens was investigated spectroscopically and the optical results were correlated with the layered anatomy of the petal. The highly directional reflected light arises from the partially transparent, pigment-bearing epidermal layer, while a more diffused yellow colour is the result of scattering from the lower starch layer. This directionality of the light reflections causes the unusually intense gloss of the buttercup flower and the strong yellow reflection evident when holding the flower under the chin.

  20. Optimization of the Chin Bar of a Composite-Shell Helmet to Mitigate the Upper Neck Force

    NASA Astrophysics Data System (ADS)

    Farajzadeh Khosroshahi, S.; Galvanetto, U.; Ghajari, M.

    2016-11-01

    The chin bar of motorcycle full-face helmets is the most likely region of the helmet to sustain impacts during accidents, with a large percentage of these impacts leading to basilar skull fracture. Currently, helmet chin bars are designed to mitigate the peak acceleration at the centre of gravity of isolated headforms, as required by standards, but they are not designed to mitigate the neck force, which is probably the cause of basilar skull fracture, a type of head injury that can lead to fatalities. Here we test whether it is possible to increase the protection of helmet chin bars while meeting standard requirements. Fibre-reinforced composite shells are commonly used in helmets due to their lightweight and energy absorption characteristics. We optimize the ply orientation of a chin bar made of fibre-reinforced composite layers for reduction of the neck force in a dummy model using a computational approach. We use the finite element model of a human head/neck surrogate and measure the neck axial force, which has been shown to be correlated with the risk of basilar skull fracture. The results show that by varying the orientation of the chin bar plies, thus keeping the helmet mass constant, the neck axial force can be reduced by approximately 30% while ensuring that the helmet complies with the impact attenuation requirements prescribed in helmet standards.

  1. Ectoparasites of the black-chinned siskin Spinus barbatus (Passeriformes: Fringillidae) in Chile.

    PubMed

    Fuentes-Castillo, Danny; Cicchino, Armando; Mironov, Sergey; Moreno, Lucila; Landaeta-Aqueveque, Carlos; Barrientos, Carlos; González-Acuña, Daniel

    2016-01-01

    Despite being a bird with a broad and extensive distribution in Chile, the black-chinned siskin, Spinus barbatus Molina, 1782 is not well studied in relation to its parasites. This paper aims to describe the ectoparasite fauna of S. barbatus in central and southern Chile. A total of 125 individuals caught with mist nets were examined alive; a total of 22 parasites were found dead and were exposed to parasit autopsy. The extracted parasites were preserved in 70% alcohol for subsequent mounting and identification. Ectoparasites were found in 56 black-chinned siskins (38%); 48 of them (33%) had 870 mites - 680 feather mites (Astigmata: Analgoidea) were identified as Proctophyllodes spini, 167 as Knemidokoptes jamaicensis, 19 as Strelkoviacarus critesi, and one as Analges passerinus. Moreover, three mites were chiggers belonging to the tribe Schoengastiini (Prostigmata: Trombiculidae). In 21 birds (14%), 54 lice were found, 21 of which were identified as Philopterus roehreri, 18 as Myrsidea serini, and 15 as Ricinus carolynae. Endoparasites were not found in the necropsied individuals. All of the parasites that were found represent new records for Chile, and they also serve as new records of host-parasite associations for S. barbatus.

  2. Reconstructive surgery with chin block graft and esthetic rehabilitation of missing anterior tooth

    PubMed Central

    Bansal, Preetika; Bansal, Pardeep

    2014-01-01

    The complete and predictable restoration of the periodontium following infection or trauma remains a critical objective in regenerative therapy. Bone grafts remain among the most widely used therapeutic strategies for the correction of periodontal osseous defects. For periodontally compromised anterior teeth, reconstruction of the ridge along with natural tooth pontic serves both the purpose of regeneration and esthetics. The right lower central incisor of a 28-year-old male that was periodontally compromised was extracted. Autogenous chin grafting followed by retrograde surgery of the extracted tooth and replacement by natural tooth pontic was done. After 6 months, there was significant improvement in clinical picture and bone fill. This procedure provided excellent regenerative and esthetic results for the periodontally compromised lost anterior tooth. PMID:24872642

  3. Growth characteristics underlying lack of a chin in pigs: a histomorphometric study

    PubMed Central

    Price, J.; Tee, B. C.; Vig, K.; Shanker, S.; Kennedy, K.; Sun, Z.

    2015-01-01

    Objectives Despite similar mandibular growth to that of humans, pigs lack a chin projection as shown in most humans. To understand whether this divergence is contributed to differences in local symphyseal growth, this project characterized bone modeling activities at the symphyseal surfaces of juvenile pigs. Material and Methods Symphyseal specimens from 2 age groups (4- and 6-month-old, n=10) were processed into histological sections with and without decalcification, which were assessed for surface mineral apposition and bone resorption, respectively. In a blinded fashion, measurements of four parameters (MAR: mineral apposition rate, MAZ: mineral apposition zone; ES/BS: eroded surface; OC.N/BS: osteoclast number) were obtained and tested by a multivariate two-way mixed-model analyses of variance (MANOVA) for the differences between symphyseal regions and ages. Results Qualitatively, pig symphyseal labial and lingual surfaces were horizontally oriented and characterized by mineral apposition and bone resorption, respectively. Quantitatively, labial mineral apposition tended to be greater rostrally than caudally at 4 months, which became greater caudally than rostrally at 6 months (region/age interactions: p=0.127 for MAR, p=0.012 for MAZ). Lingual bone resorption tended to be greater caudally than rostrally, but only ES/BS measurements was significant (p=0.039) regardless of age while OC.N/BS measurements varied with ages and regions (age/region interaction, p=0.087). Conclusions Insufficient differential in symphyseal surface modeling between the labial-caudal and labial-rostral regions contributes to the lack of chin projection in the pig. PMID:26250613

  4. Comparison of modified chin lift technique with EC technique for mask ventilation in adult apneic patients

    PubMed Central

    Rajappa, Geetha C.; Parate, Leena Harshad; Tejesh, C. A.; Prathima, P. T.

    2016-01-01

    Background: Mask ventilation (MV) is an essential basic life support skill. We used chin lift maneuver for MV and named as modified chin lift technique (MCL). EC technique is most common technique used for MV. Aims: The aim of this study is to compare the efficacy of both techniques for MV in term of expired tidal volume (TV). Secondarily, we also assessed the effect of experience on the performance of these both techniques. Settings and Design: The study area was operation theater of our hospital. This was a prospective, randomized, crossover study. Methods: A total 108 adults undergoing elective surgery under general anesthesia were recruited. In all patients, operators (novice/anesthesiologist) randomly performed both techniques either to start with EC or MCL technique. Expired TV was measured for one minute for each technique. Statistical Analysis: Paired t-test was used to compare TV. Results and Conclusion: The mean TV was significantly higher in MCL group than EC group (528.08 [104.96] ml vs. 483.39 [103] ml; P < 0.001). The novice (521.89 [117.9] ml vs. 478.70 [130.29] ml; P < 0.001) as well as anesthesiologists (534.27 [110.85] ml vs. 488.08 [111.6] ml; P < 0.001) was able to generate significantly more TV with MCL technique than EC technique. The TV did not differ significantly between novice and anesthesiologist for EC technique (P = 0.474) or MCL technique (P = 0.187). Novices as well as anesthesiologist felt MCL technique more satisfactory (70%). Clinical Trial Registration: CTRI/2016/04/006874. PMID:27746566

  5. Province-based self-remediation efficiency of the Tha Chin river basin, Thailand.

    PubMed

    Thaipichitburapa, P; Meksumpun, C; Meksumpun, S

    2010-01-01

    The Tha Chin River Basin located in the great central basin of Thailand is used for water supply, aquaculture, transportation, and recreation as well as a sink for wastewater discharges. Because of gradual deterioration of water quality and fishery resources, this study aimed to explain recent status of the river self-remediation efficiency that was influenced by nutrient inputs and outputs from the river system. Field surveys were carried out during May 2007 (early rainy season) and October 2007 (late rainy season) within the Tha Chin River located in 4 provinces; Chainat, Suphan Buri, Nakhon Pathom, and Samut Sakhon. The nutrient budgets in each province section were analyzed. Results indicated that the river was in eutrophic condition all year round. High nitrogen and phosphorus loads from surrounding agricultural land use, agro-industry, and community continuously flew into the river system. Those nutrient concentrations were higher in the early rainy season than the late rainy season. The lowest river zone (in Samut Sakhon province) indicated highest dissolved inorganic nitrogen (DIN) and orthophosphate phosphorus (P) discharges of 145.54 and 36.14 tons/day, respectively. The highest remediation efficiency of the river (ca 60% of the total input) was found in the uppermost area of Suphan Buri province. The lowest remediation efficiency (ca 12%) was found in Samut Sakhon province. From the overall view, long term monitoring of river and estuarine DIN and P should be conducted. To make better condition of aquatic environment and fishery resource in each province-based section, the controls of DIN and P remediation efficiencies (e.g. by effective management of flow speed) at 20 and 50%, respectively, were recommended.

  6. Children with Multiple Disabilities and Minimal Motor Behavior Using Chin Movements to Operate Microswitches to Obtain Environmental Stimulation

    ERIC Educational Resources Information Center

    Lancioni, Giulio E.; O'Reilly, Mark F.; Singh, Nirbhay N.; Sigafoos, Jeff; Tota, Alessia; Antonucci, Massimo; Oliva, Doretta

    2006-01-01

    In these two studies, two children with multiple disabilities and minimal motor behavior were assessed to see if they could use chin movements to operate microswitches to obtain environmental stimulation. In Study I, we applied an adapted version of a recently introduced electronic microswitch [Lancioni, G. E., O'Reilly, M. F., Singh, N. N.,…

  7. Why do humans have chins? Testing the mechanical significance of modern human symphyseal morphology with finite element analysis.

    PubMed

    Gröning, Flora; Liu, Jia; Fagan, Michael J; O'Higgins, Paul

    2011-04-01

    The modern human mandibular symphysis differs from those of all other primates in being vertically orientated and possessing a chin, but the functional significance of this unique morphology is not well understood. Some hypotheses propose that it is an adaptation to specific loads occurring during masticatory function. This study uses finite element analysis to examine these symphyseal loads in a model of a modern human mandible. By modifying the symphyseal cross-sectional form, the mechanical significance of the presence of the chin and symphyseal orientation is tested, and modern human and Neanderthal symphyseal cross-sections are compared with regard to their ability to withstand different loads. The results show that changes in symphyseal form have profound effects on the strains. The presence of a chin leads to lower symphyseal strains overall, whereas a vertical orientation of the symphysis results in higher strains under wishboning, but not under vertical bending in the coronal plane and dorsoventral shear. Compared to Neanderthals, the modern human symphysis shows higher strains during dorsoventral shear and wishboning, but is as effective as the Neanderthal symphysis in resisting vertical bending in the coronal plane and the loads resulting from simulated incision and unilateral molar biting. In general, the results of this study corroborate prior hypotheses about the mechanical effects of the human chin and vertical symphyseal orientation and support the idea that the relative importance of wishboning and vertical bending in the coronal plane might have played a role in the evolution of modern human symphyseal morphology.

  8. GM2 gangliosidosis associated with a HEXA missense mutation in Japanese Chin dogs: a potential model for Tay Sachs disease.

    PubMed

    Sanders, Douglas N; Zeng, Rong; Wenger, David A; Johnson, Gary S; Johnson, Gayle C; Decker, Jared E; Katz, Martin L; Platt, Simon R; O'Brien, Dennis P

    2013-01-01

    GM2 gangliosidosis is a fatal lysosomal storage disease caused by a deficiency of β-hexosaminidase (EC 3.2.1.52). There are two major isoforms of the enzyme: hexosaminidase A composed of an α and a β subunit (encoded by HEXA and HEXB genes, respectively); and, hexosaminidase B composed of two β subunits. Hexosaminidase A requires an activator protein encoded by GM2A to catabolize GM2 ganglioside, but even in the absence of the activator protein, it can hydrolyze the synthetic substrates commonly used to assess enzyme activity. GM2 gangliosidosis has been reported in Japanese Chin dogs, and we identified the disease in two related Japanese Chin dogs based on clinical signs, histopathology and elevated brain GM2 gangliosides. As in previous reports, we found normal or elevated hexosaminidase activity when measured with the synthetic substrates. This suggested that the canine disease is analogous to human AB variant of G(M2) gangliosidosis, which results from mutations in GM2A. However, only common neutral single nucleotide polymorphisms were found upon sequence analysis of the canine ortholog of GM2A from the affected Japanese Chins. When the same DNA samples were used to sequence HEXA, we identified a homozygous HEXA:c967G>A transition which predicts a p.E323K substitution. The glutamyl moiety at 323 is known to make an essential contribution to the active site of hexosaminidase A, and none of the 128 normal Japanese Chins and 92 normal dogs of other breeds that we tested was homozygous for HEXA:c967A. Thus it appears that the HEXA:c967G>A transition is responsible for the GM2 gangliosidosis in Japanese Chins.

  9. Grafts and implants in nasal and chin augmentation. A rational approach to material selection.

    PubMed

    Adams, J S

    1987-11-01

    considered. A good example is the nose. Its mobility and thin soft-tissue coverage lead to extrusion of firm implants such as Silastic. By contrast, Silastic works well for chin augmentation. Also, consider present or future bacterial contamination in the area. This is especially important in nasal augmentation, where infection and extrusion can lead to unacceptable deformities. In general, nasal augmentation is best achieved in most circumstances by cartilage. If this is unavailable, then Supramid has a proven record for good tissue compatibility and resistance to infection. For the chin, Silastic (either rubber- or gel-filled prostheses) produces the most pleasing and long-lasting results.

  10. Prostate adenocarcinoma mandibular metastasis associated with numb chin syndrome: a case report

    PubMed Central

    2016-01-01

    The purpose of this study is to report a rare case of mandibular adenocarcinoma that was diagnosed due to metastasis from the prostate. Numb chin syndrome (NCS), which was associated with this case, is also discussed. Computed tomography (CT) and an intraoral incisional biopsy of the left mandibular area were performed. Urology consultation, hormone therapy, chemotherapy and follow-up radiographic images were administered. Histological examination of the incised specimen revealed moderately differentiated adenocarcinoma. The Gleason score was 8 (primary 4/secondary 4). Immunohistochemical features and radiographic results confirmed the diagnosis of metastasis from prostate adenocarcinoma, moderately differentiated. The patient's prostate-specific antigen (PSA) level was very high. After hormone treatment, the patient's PSA levels dropped gradually. Seventeen months later, in May 2015, the PSA level was elevated. The 18-month follow-up CT image indicated that the patient's condition was aggravated. Docetaxel chemotherapy was started in June 2015 (18 months later), and the sixth cycle of the therapy is in progress. Oral metastases that originate from prostate adenocarcinoma are rare and can induce various periosteal reactions. Hormone therapy, chemotherapy and close follow-up could be additional, appropriate treatment, and were applied in this case. Finally, NCS is a valuable indicator of metastatic disease in the mandible. PMID:27847740

  11. Teaghrelins, unique acylated flavonoid tetraglycosides in Chin-shin oolong tea, are putative oral agonists of the ghrelin receptor.

    PubMed

    Lo, Yuan-Hao; Chen, Ying-Jie; Chang, Chi-I; Lin, Yi-Wen; Chen, Chung-Yu; Lee, Maw-Rong; Lee, Viola S Y; Tzen, Jason T C

    2014-06-04

    Chin-shin oolong tea, a popular tea in Taiwan, was empirically perceived to induce hunger and accelerate gastric emptying in a manner similar to the physiological effects of ghrelin, an endogenous acylated peptide known as the hunger hormone. Two unique acylated flavonoid tetraglycosides previously identified in Chin-shin oolong tea were demonstrated to induce hunger of rats in a food intake assay and, thus, named teaghrelin-1 and teaghrelin-2. Similar to GHRP-6, a synthetic analogue of ghrelin, teaghrelin-1 stimulated growth hormone secretion of rat primary anterior pituitary cells in a dose-dependent manner, and the stimulation was inhibited by [D-Arg(1),D-Phe(5),D-Trp(7,9),Leu(11)]-substance P, an antagonist of the ghrelin receptor. While teaghrelin-2 remained unmodified, a meta-O-methylated metabolite of teaghrelin-1 was detected in bile of rats after intravenous injection. Presumably, teaghrelins are promising oral agonists of the ghrelin receptor.

  12. Seismic Observations of the 15 February 2013 Chelyabinsk Meteor from Dense ChinArray

    NASA Astrophysics Data System (ADS)

    LI, L.; Wang, B.; Peng, Z.; Wang, W.

    2014-12-01

    Since the 1908 Tunguska event, the largest meteor was reported on 15 February 2013 around 03:20:00 UTC. The fireball exploded and dropped near Chelyabinsk, Russia. Massive energy released by meteor crash was recorded by the 500-station ChinArray deployed in southwest China at distances more than 4000 kilometers from the meteor event. About 20 minutes before the meteor event, an M5.8 event occurred in Tonga, and produced seismic waves that overlapped with the seismic signals from the meteor event. Here we separate the seismic phases from the two events using standard array processing techniques such as F-K analysis, beam-forming, and vespagram in the Generic Array Processing (GAP) code (Koper, 2005). F-K analysis provides an effective way to calculate the back azimuth and slowness of a seismic phase. With this method, we identify a phase with back azimuth of 339.1°and slowness of 37.46sec/deg as surface wave from meteor. Beam-forming technique can be used to amplify the signal of meteor generated surface wave and suppress incoherent noise and phases with different slowness from the Tonga event. Vespagram shows the appropriate slowness of ~35sec/deg at arrival of meteor's phase, confirming the F-K detection of surface wave. From the surface wave observation, we conclude that the seismic source of meteor is located on 61.39N 58.70E, which is ~700km away from the USGS location (55.15N 61.41E). Using the Praha relation [Karnik et al., 1962], we estimate a magnitude of Ms=3.94±0.18 in accordance with that of Ms~3.7 [Benoit Tauzin et al., 2013]. Our result is comparable to other observations with shorter epicentral distances, suggesting that dense seismic arrays can be used to detect weak seismic signals at long-range distances.

  13. Effect of frontal facial type and sex on preferred chin projection

    PubMed Central

    Choi, Jin-Young; Kim, Taeyun; Kim, Hyung-Mo; Lee, Sang-Hoon; Cho, Il-sik

    2017-01-01

    Objective To investigate the effects of frontal facial type (FFT) and sex on preferred chin projection (CP) in three-dimensional (3D) facial images. Methods Six 3D facial images were acquired using a 3D facial scanner (euryprosopic [Eury-FFT], mesoprosopic [Meso-FFT], and leptoprosopic [Lepto-FFT] for each sex). After normal CP in each 3D facial image was set to 10° of the facial profile angle (glabella–subnasale-pogonion), CPs were morphed by gradations of 2° from normal (moderately protrusive [6°], slightly protrusive [8°], slightly retrusive [12°], and moderately retrusive [14°]). Seventy-five dental students (48 men and 27 women) were asked to rate the CPs (6°, 8°, 10°, 12°, and 14°) from the most to least preferred in each 3D image. Statistical analyses included the Kolmogorov-Smirnov test, Kruskal-Wallis test, and Bonferroni correction. Results No significant difference was observed in the distribution of preferred CP in the same FFT between male and female evaluators. In Meso-FFT, the normal CP was the most preferred without any sex difference. However, in Eury-FFT, the slightly protrusive CP was favored in male 3D images, but the normal CP was preferred in female 3D images. In Lepto-FFT, the normal CP was favored in male 3D images, whereas the slightly retrusive CP was favored in female 3D images. The mean preferred CP angle differed significantly according to FFT (Eury-FFT: male, 8.7°, female, 9.9°; Meso-FFT: male, 9.8°, female, 10.7°; Lepto-FFT: male, 10.8°, female, 11.4°; p < 0.001). Conclusions Our findings might serve as guidelines for setting the preferred CP according to FFT and sex. PMID:28337420

  14. Relationship between chin deviation and the position and morphology of the mandible in individuals with a unilateral cleft lip and palate

    PubMed Central

    Kim, Kyung-Seon; Park, Soo-Byung; Kim, Seong-Sik; Kim, Yong-Il

    2013-01-01

    Objective In this study, we aimed to examine the relationship between chin deviation and the positional and morphological features of the mandible and to determine the factors that contributed to chin deviation in individuals with a unilateral cleft lip and palate (UCLP). Methods Cone-beam computed tomography (CBCT) images of 28 adults with UCLP were analyzed in this study. Segmented three-dimensional temporomandibular fossa and mandible images were reconstructed, and angular, linear, and volumetric parameters were measured. Results For all 28 individuals, the chin was found to deviate to the cleft side by 1.59 mm. Moreover, among these 28 individuals, only 7 showed distinct (more than 4 mm) chin deviation, which was toward the cleft side. Compared to the non-cleft side, the mandibular body length, frontal ramal inclination, and vertical position of the condyle were lower and inclination of the temporomandibular fossa was steeper on the cleft side. Furthermore, the differences in inclination of the temporomandibular fossa, mandibular body length, ramus length, and condylar volume ratio (non-deviated/deviated) were positively correlated with chin deviation. Conclusions UCLP individuals show mild chin deviation to the cleft side. Statistical differences were noted in the parameters that represented positional and morphological asymmetries of the mandible and temporomandibular fossa; however, these differences were too small to indicate clinical significance. PMID:24015386

  15. Quantifying the uncertainties of climate change effects on the storage-yield and performance characteristics of the Pong multi-purpose reservoir, India

    NASA Astrophysics Data System (ADS)

    Soundharajan, B.; Adeloye, A. J.; Remesan, R.

    2015-06-01

    Climate change is predicted to affect water resources infrastructure due to its effect on rainfall, temperature and evapotranspiration. However, there are huge uncertainties on both the magnitude and direction of these effects. The Pong reservoir on the Beas River in northern India serves irrigation and hydropower needs. The hydrology of the catchment is highly influenced by Himalayan seasonal snow and glaciers, and Monsoon rainfall; the changing pattern of the latter and the predicted disappearance of the former will have profound effects on the performance of the reservoir. This study employed a Monte-Carlo simulation approach to characterise the uncertainties in the future storage requirements and performance of the reservoir. Using a calibrated rainfall-runoff (R-R) model, the baseline runoff scenario was first simulated. The R-R inputs (rainfall and temperature) were then perturbed using plausible delta-changes to produce simulated climate change runoff scenarios. Stochastic models of the runoff were developed and used to generate ensembles of both the current and climate-change perturbed future scenarios. The resulting runoff ensembles were used to simulate the behaviour of the reservoir and determine "populations" of reservoir storage capacity and performance characteristics. Comparing these parameters between the current and the perturbed provided the population of climate change effects which was then analysed to determine the uncertainties. The results show that contrary to the usual practice of using single records, there is wide variability in the assessed impacts. This variability or uncertainty will, no doubt, complicate the development of climate change adaptation measures; however, knowledge of its sheer magnitude as demonstrated in this study will help in the formulation of appropriate policy and technical interventions for sustaining and possibly enhancing water security for irrigation and other uses served by Pong reservoir.

  16. Health and Human Rights in Chin State, Western Burma: A Population-Based Assessment Using Multistaged Household Cluster Sampling

    PubMed Central

    Sollom, Richard; Richards, Adam K.; Parmar, Parveen; Mullany, Luke C.; Lian, Salai Bawi; Iacopino, Vincent; Beyrer, Chris

    2011-01-01

    Background The Chin State of Burma (also known as Myanmar) is an isolated ethnic minority area with poor health outcomes and reports of food insecurity and human rights violations. We report on a population-based assessment of health and human rights in Chin State. We sought to quantify reported human rights violations in Chin State and associations between these reported violations and health status at the household level. Methods and Findings Multistaged household cluster sampling was done. Heads of household were interviewed on demographics, access to health care, health status, food insecurity, forced displacement, forced labor, and other human rights violations during the preceding 12 months. Ratios of the prevalence of household hunger comparing exposed and unexposed to each reported violation were estimated using binomial regression, and 95% confidence intervals (CIs) were constructed. Multivariate models were done to adjust for possible confounders. Overall, 91.9% of households (95% CI 89.7%–94.1%) reported forced labor in the past 12 months. Forty-three percent of households met FANTA-2 (Food and Nutrition Technical Assistance II project) definitions for moderate to severe household hunger. Common violations reported were food theft, livestock theft or killing, forced displacement, beatings and torture, detentions, disappearances, and religious and ethnic persecution. Self reporting of multiple rights abuses was independently associated with household hunger. Conclusions Our findings indicate widespread self-reports of human rights violations. The nature and extent of these violations may warrant investigation by the United Nations or International Criminal Court. Please see later in the article for the Editors' Summary PMID:21346799

  17. Benefit from the Chin-Down Maneuver in the Swallowing Performance and Self-Perception of Parkinson's Disease Patients

    PubMed Central

    Jotz, Geraldo Pereira

    2017-01-01

    Aims. To verify the effectiveness of the maneuver application in swallowing therapy with PD. Materials and Method. We performed an open-label trial, with three groups compounds by PD individuals: the experimental group, control group, and orientation group. The study included PD patients with dysphagia. A cognitive screening, through a questionnaire about depression and quality of life, was conducted. Swallowing assessment was performed through (1) fiberoptic endoscopic evaluation of swallowing (FEES); (2) clinical evaluation and Functional Oral Intake Scale (FOIS); and (3) assessment of the quality life related to swallowing (SWALQOL). A therapeutic program, which consisted of chin-down postural maneuver and orientations on feeding, was applied. Both groups (EG and OG) received on-month therapeutic program. Results. A significant improvement in swallowing, evaluated by clinical assessment, was observed in solid (p < 0.001) and liquid (p = 0.022) consistencies in EG when compared to OG and CG. Patients in EG presented improvement in QoL, with the significant difference in comparison with the other groups, about domain frequency of symptoms (p = 0.029) in SWALQOL questionnaire. Conclusion. The postural maneuver chin-down improved swallowing performance and self-perception, but not the laryngeal signs. This trial is registered with registration number NCT02973698. PMID:28203475

  18. Histone-derived piRNA biogenesis depends on the ping-pong partners Piwi5 and Ago3 in Aedes aegypti.

    PubMed

    Girardi, Erika; Miesen, Pascal; Pennings, Bas; Frangeul, Lionel; Saleh, Maria-Carla; van Rij, Ronald P

    2017-01-23

    The piRNA pathway is of key importance in controlling transposable elements in most animal species. In the vector mosquito Aedes aegypti, the presence of eight PIWI proteins and the accumulation of viral piRNAs upon arbovirus infection suggest additional functions of the piRNA pathway beyond genome defense. To better understand the regulatory potential of this pathway, we analyzed in detail host-derived piRNAs in A. aegypti Aag2 cells. We show that a large repertoire of protein-coding genes and non-retroviral integrated RNA virus elements are processed into genic piRNAs by different combinations of PIWI proteins. Among these, we identify a class of genes that produces piRNAs from coding sequences in an Ago3- and Piwi5-dependent fashion. We demonstrate that the replication-dependent histone gene family is a genic source of ping-pong dependent piRNAs and that histone-derived piRNAs are dynamically expressed throughout the cell cycle, suggesting a role for the piRNA pathway in the regulation of histone gene expression. Moreover, our results establish the Aag2 cell line as an accessible experimental model to study gene-derived piRNAs.

  19. Nernst-ping-pong model for evaluating the effects of the substrate concentration and anode potential on the kinetic characteristics of bioanode.

    PubMed

    Peng, Sikan; Liang, Da-Wei; Diao, Peng; Liu, Yanyan; Lan, Fei; Yang, Yuhan; Lu, Shanfu; Xiang, Yan

    2013-05-01

    Understanding the electron-transfer mechanism and kinetic characteristics of bioanodes is greatly significant to enhance the electron-generating efficiencies in bioelectrochemical systems (BESs). A Nernst-ping-pong model is proposed here to investigate the kinetics and biochemical processes of bioanodes in a microbial electrolysis cell. This model can accurately describe the effects of the substrate (including substrate inhibition) and the anode potential on the current of bioanodes. Results show that the half-wave potential positively shifts as the substrate concentration increases, indicating that the rate-determining steps of anodic processes change from substrate oxidation to intracellular electron transport reaction. The anode potential has negligible effects on the enzymatic catalysis of anodic microbes in the range of -0.25 V to +0.1 V vs. a saturated calomel electrode. It turns out that to reduce the anodic energy loss caused by overpotential, higher substrate concentrations are preferred, if the substrate do not significantly and adversely affect the output current.

  20. Aub and Ago3 are recruited to nuage through two mechanisms to form a ping-pong complex assembled by Krimper

    PubMed Central

    Webster, Alexandre; Li, Sisi; Hur, Junho K.; Wachsmuth, Malte; Bois, Justin S.; Perkins, Edward M.; Patel, Dinshaw J.; Aravin, Alexei A.

    2015-01-01

    In Drosophila, two Piwi proteins, Aubergine (Aub) and Argonaute-3 (Ago3) localize to perinuclear ‘nuage’ granules and use guide piRNAs to target and destroy transposable element transcripts. We find that Aub and Ago3 are recruited to nuage by two different mechanisms. Aub requires a piRNA guide for nuage recruitment, indicating that its localization depends on recognition of RNA targets. Ago3 is recruited to nuage independently of a piRNA cargo and relies on interaction with Krimper, a stable component of nuage that is able to aggregate in the absence of other nuage proteins. We show that Krimper interacts directly with Aub and Ago3 to coordinate the assembly of the ping-pong piRNA processing (4P) complex. Symmetrical dimethylated arginines are required for Aub to interact with Krimper, but are dispensable for Ago3 to bind Krimper. Our study reveals a multi-step process responsible for the assembly and function of nuage complexes in piRNA-guided transposon repression. PMID:26295961

  1. Bilateral Numb Chin Syndrome as the Initial Presentation of Burkitt's Lymphoma/Leukemia: A Report of Two Cases and Review of the Literature

    PubMed Central

    Bassuni, Wafaa; Adas, Reem

    2016-01-01

    Numb chin syndrome, also known as mental nerve neuropathy, is a rare sensory neuropathy characterized by paresthesia and hypoesthesia in the area supplied by the mental nerve and its branches. This syndrome may be the first symptom of underlying malignancy or the first sign of recurrence and metastasis in patients with preexisting cancer. In this article, we present two cases with bilateral numb chin syndrome as the first manifestation of Burkitt's lymphoma/leukemia and review the relevant literature. Numb chin syndrome should be considered as a warning sign and raise the suspicion for an underlying malignancy. Bilateral involvement is especially hazardous and must not be underestimated. In fact, an astute neurologist and internist who realizes that chin numbness is a potentially significant symptom can then exclude serious underlying malignancies. Standard diagnostic protocol with different modalities of imaging based on the availability and experience of the radiology team should be mandatory. High index of suspicion should be practiced to avoid delay in diagnosis and progression of the underlying malignancy. PMID:27882251

  2. Bilateral Numb Chin Syndrome as the Initial Presentation of Burkitt's Lymphoma/Leukemia: A Report of Two Cases and Review of the Literature.

    PubMed

    Algahtani, Hussein; Shirah, Bader; Bassuni, Wafaa; Adas, Reem

    2016-01-01

    Numb chin syndrome, also known as mental nerve neuropathy, is a rare sensory neuropathy characterized by paresthesia and hypoesthesia in the area supplied by the mental nerve and its branches. This syndrome may be the first symptom of underlying malignancy or the first sign of recurrence and metastasis in patients with preexisting cancer. In this article, we present two cases with bilateral numb chin syndrome as the first manifestation of Burkitt's lymphoma/leukemia and review the relevant literature. Numb chin syndrome should be considered as a warning sign and raise the suspicion for an underlying malignancy. Bilateral involvement is especially hazardous and must not be underestimated. In fact, an astute neurologist and internist who realizes that chin numbness is a potentially significant symptom can then exclude serious underlying malignancies. Standard diagnostic protocol with different modalities of imaging based on the availability and experience of the radiology team should be mandatory. High index of suspicion should be practiced to avoid delay in diagnosis and progression of the underlying malignancy.

  3. Tales of Recombinant Femininity: "The Reincarnation of Golden Lotus," the "Chin P'ing Mei," and the Politics of Melodrama in Hong Kong.

    ERIC Educational Resources Information Center

    Fore, Steve

    1993-01-01

    Examines the film "The Reincarnation of Golden Lotus" and the text upon which it is loosely based, the "Chin P'ing Mei," and the relationship between it and modern Chinese culture. States that the film's screenplay is much less an adaptation of the source novel than it is a female-centered reworking of a particular narrative…

  4. Bone quality at the implant site after reconstruction of a local defect of the maxillary anterior ridge with chin bone or deproteinised cancellous bovine bone.

    PubMed

    Meijndert, L; Raghoebar, G M; Schüpbach, P; Meijer, H J A; Vissink, A

    2005-12-01

    The purpose of this study was to investigate the quality of bone at grafted implant sites in the anterior maxilla. Grafting of these sites was necessary because of insufficient bone volume in a buccopalatinal direction (width at the top of the crest 1-3mm). Reconstruction was performed with chin bone (N=5), chin bone and a resorbable Bio-Gide GBR membrane (N=5) or Bio-Oss spongiosa granules in combination with a Bio-Gide GBR membrane (N=5). Biopsies were taken prior to implantation, i.e. 3 months after grafting with chin bone, and 6 months after grafting with Bio-Oss. Evaluation was done by assessing the histological and histomorphometric characteristics of full-length biopsies taken from the actual implant site. Both areas with non-vital bone and areas with apposition of bone and remodelling phenomena were observed in the chin bone group at the time of placement of the implants. Similar results were observed at implant sites reconstructed with a chin bone graft covered by a membrane. In the chin bone group without and with a GBR membrane, the mean total bone volume (TBV) was 55.2+/-6.8% and 57.7+/-11.5%, respectively; the marrow connective tissue volume (MCTV) was 44.8+/-6.8% and 42.3+/-11.5%, respectively. Remnants of the resorbable GBR membrane were not detected. In the Bio-Oss((R)) group, at implant placement some newly formed bone was observed in the connective tissue surrounding the Bio-Oss((R)) particles (mean TBV (newly formed bone) 17.6+/-14.5%), but most particles were surrounded by connective tissue. No convincing signs of remodelling were observed (mean remaining Bio-Oss volume 40.5+/-9.3%; mean MCTV 41.9+/-13.1%). No implants were lost during follow up (12 months). At the time of placement of the implants the grafting material (either chin bone or Bio-Oss is still not fully replaced by new vital bone. In case of Bio-Oss, most of the grafting material is even still present. Despite these differences, the 1-year clinical results were very good and

  5. Amicyanin transfers electrons from methylamine dehydrogenase to cytochrome c-551i via a ping-pong mechanism, not a ternary complex.

    PubMed

    Meschi, Francesca; Wiertz, Frank; Klauss, Linda; Cavalieri, Chiara; Blok, Anneloes; Ludwig, Bernd; Heering, Hendrik A; Merli, Angelo; Rossi, Gian Luigi; Ubbink, Marcellus

    2010-10-20

    The first crystal structure of a ternary redox protein complex was comprised of the enzyme methylamine dehydrogenase (MADH) and two electron transfer proteins, amicyanin and cytochrome c-551i from Paracoccus denitrificans [Chen et al. Science 1994, 264, 86-90]. The arrangement of the proteins suggested possible electron transfer from the active site of MADH via the amicyanin copper ion to the cytochrome heme iron, although the distance between the metals is large. We studied the interactions between these proteins in solution. A titration followed by NMR spectroscopy shows that amicyanin binds cytochrome c-551i. The interface comprises the hydrophobic and positive patches of amicyanin, not the binding site observed in the ternary complex. NMR experiments further show that amicyanin binds tightly to MADH with an interface that matches the one observed in the crystal structure and that mostly overlaps with the binding site for cytochrome c-551i. Upon addition of cytochrome c-551i, no changes in the NMR spectrum of MADH-bound amicyanin are observed, suggesting that a possible interaction of the cytochrome with the binary complex must be very weak, with a dissociation constant higher than 2 mM. Reconstitution of the entire redox chain in vitro demonstrates that amicyanin can react rapidly with cytochrome c-551i, but that association of amicyanin with MADH inhibits this reaction. It is concluded that electron transfer from MADH to cytochrome c-551i does not involve a ternary complex but occurs via a ping-pong mechanism in which amicyanin uses the same interface for the reactions with MADH and cytochrome c-551i.

  6. Size and placement of developing anterior teeth in immature Neanderthal mandibles from Dederiyeh Cave, Syria: implications for emergence of the modern human chin.

    PubMed

    Fukase, Hitoshi; Kondo, Osamu; Ishida, Hajime

    2015-03-01

    Evolutionary and functional significance of the human chin has long been explored from various perspectives including masticatory biomechanics, speech, and anterior tooth size. Recent ontogenetic studies have indicated that the spatial position of internally forming anterior teeth partially constrains adult mandibular symphyseal morphology. The present study therefore preliminarily examined the size and placement of developing anterior teeth in immature Neanderthal mandibles of Dederiyeh 1 and 2, compared with similarly-aged modern humans (N = 16) and chimpanzees (N = 7) whose incisors are comparatively small and large among extant hominids, respectively. The Dederiyeh 1 mandible is described as slightly presenting a mental trigone and attendant mental fossa, whereas Dederiyeh 2 completely lacks such chin-associated configurations. Results showed that, despite symphyseal size being within the modern human range, both Dederiyeh mandibles accommodated overall larger anterior dentition and displayed a remarkably wide bicanine space compared to those of modern humans. Dederiyeh 2 had comparatively thicker deciduous incisor roots and more enlarged permanent incisor crypts than Dederiyeh 1, but both Dederiyeh individuals exhibited a total dental size mostly intermediate between modern humans and chimpanzees. These findings potentially imply that the large deciduous/permanent incisors collectively distended the labial alveolar bone, obscuring an incipient mental trigone. It is therefore hypothesized that the appearance of chin-associated features, particularly of the mental trigone and fossa, can be accounted for partly by developmental relationships between the sizes of the available mandibular space and anterior teeth. This hypothesis must be, however, further addressed with more referential samples in future studies.

  7. Growth data of underprivileged children living in rural areas of Chin State, Burma/Myanmar, compared to the WHO reference growth standards: an observational study

    PubMed Central

    Prenkert, Malin; Ehnfors, Margareta

    2016-01-01

    Objectives To explore growth data (height-for-age, weight-for-age and BMI-for-age) of children living in poor socioeconomic conditions in rural areas of Chin State, Burma/Myanmar; and to compare these data with the growth and development z-score (GDZ) values for school-aged children and adolescents, provided by the WHO. Setting A support and educational programme, run by the Swedish association Chin Development and Research Society (CDRS), was carried out among underprivileged school-aged children, unable to attend school without economic and practical support, living in villages and remote areas in Chin State. Participants Community leaders who were well familiar with the citizens in the community identified children in need of this support. Other community members could also suggest or apply for this. The sample includes all participating children in the CDRS programme at the time of the data collection in six townships. The children were placed in host families, close to a suitable school. Two samples with a total of 639 children from 144 villages and remote areas were obtained: 1. Children in the CDRS Chin Programme (CCP) (2007–2010) comprised 558 children: 50% girls and boys. 2. Children in the Chin Society (CCS) (2010) comprised 81 children: 44% girls and 56% boys. Primary outcome measures Growth data. Results All growth data from both groups deviated significantly from the WHO standard references (p≤0.001). The prevalence of stunting (height-for-age ≤–2SD) was 52% among girls and 68% among boys. High levels of wasting (weight-for-age ≤–2SD) were found among girls 29% and boys 36% aged 5–10 years. In addition, severe thinness (BMI-for-age ≤–2SD) was found among girls 31% and boys 44%, all results to be compared to the expected 2.27%. Conclusions Many more than expected—according to the WHO reference values—in CCP and CCS suffered from stunting, wasting and thinness. PMID:26787249

  8. Comparative Analysis of Reproductive Traits in Black-Chinned Tilapia Females from Various Coastal Marine, Estuarine and Freshwater Ecosystems

    PubMed Central

    Kantoussan, Justin; Ndiaye, Papa; Thiaw, Omar Thiom; Albaret, Jean-Jacques

    2012-01-01

    The black-chinned tilapia Sarotherodon melanotheron is a marine teleost characterised by an extreme euryhalinity. However, beyond a certain threshold at very high salinity, the species exhibits impaired growth and precocious reproduction. In this study, the relationships between reproductive parameters, environmental salinity and condition factor were investigated in wild populations of this species that were sampled in two consecutive years (2003 and 2004) from three locations in Senegal with different salinities: Guiers lake (freshwater, 0 psu), Hann bay (seawater, 37 psu) and Saloum estuary (hypersaline water, 66–127 psu). The highest absolute fecundity and spawning weight were recorded in seawater by comparison to either freshwater or hypersaline water whereas the poorest condition factors were observed in the most saline sampling site. These results reflect higher resource allocation to the reproduction due to the lowest costs of adaptation to salinity in seawater (the natural environment of this species) rather than differences in food resources at sites and/or efficiency at foraging and prey availability. Fecundities, oocyte size as well as spawning weight were consistent from year to year. However, the relative fecundity in the Saloum estuary varied significantly between the dry and rainy raisons with higher values in the wet season, which seems to reflect seasonal variations in environmental salinity. Such a reproductive tactic of producing large amounts of eggs in the rainy season when the salinity in the estuary was lower, would give the fry a better chance at survival and therefore assures a high larval recruitment. An inverse correlation was found between relative fecundity and oocyte size at the two extreme salinity locations, indicating that S. melanotheron has different reproductive strategies in these ecosystems. The adaptive significance of these two reproductive modes is discussed in regard to the heavy osmotic constraint imposed by extreme

  9. Comparative analysis of reproductive traits in black-chinned tilapia females from various coastal marine, estuarine and freshwater ecosystems.

    PubMed

    Guèye, Moussa; Tine, Mbaye; Kantoussan, Justin; Ndiaye, Papa; Thiaw, Omar Thiom; Albaret, Jean-Jacques

    2012-01-01

    The black-chinned tilapia Sarotherodon melanotheron is a marine teleost characterised by an extreme euryhalinity. However, beyond a certain threshold at very high salinity, the species exhibits impaired growth and precocious reproduction. In this study, the relationships between reproductive parameters, environmental salinity and condition factor were investigated in wild populations of this species that were sampled in two consecutive years (2003 and 2004) from three locations in Senegal with different salinities: Guiers lake (freshwater, 0 psu), Hann bay (seawater, 37 psu) and Saloum estuary (hypersaline water, 66-127 psu). The highest absolute fecundity and spawning weight were recorded in seawater by comparison to either freshwater or hypersaline water whereas the poorest condition factors were observed in the most saline sampling site. These results reflect higher resource allocation to the reproduction due to the lowest costs of adaptation to salinity in seawater (the natural environment of this species) rather than differences in food resources at sites and/or efficiency at foraging and prey availability. Fecundities, oocyte size as well as spawning weight were consistent from year to year. However, the relative fecundity in the Saloum estuary varied significantly between the dry and rainy raisons with higher values in the wet season, which seems to reflect seasonal variations in environmental salinity. Such a reproductive tactic of producing large amounts of eggs in the rainy season when the salinity in the estuary was lower, would give the fry a better chance at survival and therefore assures a high larval recruitment. An inverse correlation was found between relative fecundity and oocyte size at the two extreme salinity locations, indicating that S. melanotheron has different reproductive strategies in these ecosystems. The adaptive significance of these two reproductive modes is discussed in regard to the heavy osmotic constraint imposed by extreme

  10. Tribute to Christine Chin

    ERIC Educational Resources Information Center

    Teo, Tang Wee; Tan, Aik-Ling

    2015-01-01

    It has been more than 3 years since Christine left us. She has left a lasting legacy of her academic brilliance among the science education community. This paper pays tribute to Christine's fine research work that has shaped and continues to shape science education research in the field of questioning and argumentation.

  11. Mystery behind Non-Healing Wound at Chin Region - Myiasis due to Neglected Trauma - A Case Report with Review of Literature.

    PubMed

    Khandelwal, Pulkit; Hajira, Neha

    2016-06-01

    Myiasis is the infestation of human beings with fly larvae which feed on host's living or dead tissue. Diagnosis of this condition is made by the presence of larvae in affected body parts. The standard treatment is the mechanical removal of the maggots from the lesion and management of the general systemic condition. This paper report a case of myiasis at the chin region in a 45-year-old male managed by manual removal of larvae after topical application of turpentine oil, surgical debridement of necrotic tissues and antimicrobial therapy.

  12. A case of mimicking angioedema: chin silicone granulomatous reaction spreading all over the face after receiving liquid silicone injection forty years previously.

    PubMed

    Chen, Yu-Cheng; Chen, Mei-Ling; Chiu, Ying-Ming

    2011-06-01

    Liquid injectable silicone has been used for soft tissue augmentation for five decades. Many complications following liquid silicone injection have been reported. To diagnose and manage silicone granuloma remains difficult. Silicone granuloma must be diagnosed with the history of liquid silicone injection and the histology of tissue biopsy. We presented a case of granulomatous reaction after the injection of liquid silicone for chin augmentation forty years ago, causing total facial swelling, which mimicking angioedema initially. We administered methylprednisolone to the patient. Initial response to methylprednisolone was favorable.

  13. Structures of NADH and CH[subscript 3]-H[subscript 4] Folate Complexes of Escherichia coli Methylenetetrahydrofolate Reductase Reveal a Spartan Strategy for a Ping-Pong Reaction

    SciTech Connect

    Pejchal, Robert; Sargeant, Ryan; Ludwig, Martha L.

    2010-03-08

    Methylenetetrahydrofolate reductases (MTHFRs; EC 1.7.99.5) catalyze the NAD(P)H-dependent reduction of 5,10-methylenetetrahydrofolate (CH{sub 2}-H{sub 4}folate) to 5-methyltetrahydrofolate (CH{sub 3}-H{sub 4}folate) using flavin adenine dinucleotide (FAD) as a cofactor. The initial X-ray structure of Escherichia coli MTHFR revealed that this 33-kDa polypeptide is a ({beta}{alpha}){sub 8} barrel that aggregates to form an unusual tetramer with only 2-fold symmetry. Structures of reduced enzyme complexed with NADH and of oxidized Glu28Gln enzyme complexed with CH{sub 3}-H{sub 4}folate have now been determined at resolutions of 1.95 and 1.85 {angstrom}, respectively. The NADH complex reveals a rare mode of dinucleotide binding; NADH adopts a hairpin conformation and is sandwiched between a conserved phenylalanine, Phe223, and the isoalloxazine ring of FAD. The nicotinamide of the bound pyridine nucleotide is stacked against the si face of the flavin ring with C4 adjoining the N5 of FAD, implying that this structure models a complex that is competent for hydride transfer. In the complex with CH{sub 3}-H{sub 4}folate, the pterin ring is also stacked against FAD in an orientation that is favorable for hydride transfer. Thus, the binding sites for the two substrates overlap, as expected for many enzymes that catalyze ping-pong reactions, and several invariant residues interact with both folate and pyridine nucleotide substrates. Comparisons of liganded and substrate-free structures reveal multiple conformations for the loops {beta}2-{alpha}2 (L2), {beta}3-{alpha}3 (L3), and {beta}4-{alpha}4 (L4) and suggest that motions of these loops facilitate the ping-pong reaction. In particular, the L4 loop adopts a 'closed' conformation that allows Asp120 to hydrogen bond to the pterin ring in the folate complex but must move to an 'open' conformation to allow NADH to bind.

  14. Characterization and determination of lipophilic hydrocarbons in the Chao Phraya, Bang Pakong and Tha-Chin rivers and the Upper Gulf of Thailand.

    PubMed

    Onodera, S; Chatkittikunrong, W; Saito, K; Phongbetchara, R; Tabucanon, M

    1987-04-17

    Carbon tetrachloride extracts of water samples collected from the Chao Phraya, Bang Pakong and Tha-Chin rivers and the Upper Gulf of Thailand in the rainy season (1983) and dry season (1984) were studied in order to characterize and determine the lipophilic hydrocarbons. The major lipophilic organic compounds present were n-alkanes (C17-C33), dibutyl phthalate and di(2-ethylhexyl) phthalate. However, polyaromatic hydrocarbons were hardly detectable level (0.1 microgram/l by high-performance liquid chromatography). The concentrations of these lipophilic hydrocarbons were correlated with the effective rainfall content of the river. These data suggest a multiplicity of sources ranging from indigenous biological materials to petroleum activities.

  15. Multiparametric approach for assessing environmental quality variations in West African aquatic ecosystems using the black-chinned tilapia (Sarotherodon melanotheron) as a sentinel species.

    PubMed

    Ndiaye, Awa; Sanchez, Wilfried; Durand, Jean-Dominique; Budzinski, Hélène; Palluel, Olivier; Diouf, Khady; Ndiaye, Papa; Panfili, Jacques

    2012-11-01

    The study highlights the potential of the black-chinned tilapia to be used as a sentinel to assess environmental contaminants based on the use of a set of biomarkers. The usefulness of fish species as sentinels for assessing aquatic environment contamination was tested using a set of biomarkers in Senegalese environments characterized by multi-pollution sources. The black-chinned tilapia (Sarotherodon melanotheron) was selected as a sentinel because of its abundance, wide distribution in all coastal aquatic ecosystems and physiological properties. The potential influence of confounding factors such as salinity on biomarker in the tilapia has been examined. Individuals were sampled during two seasons (dry and wet) in eight sites characterized by various degrees of anthropogenic contamination and different salinities (from 0 to 102 psu). Biomarkers-including growth rate (GR), condition factor (CF), biotransformation enzymes such as 7-ethoxyresorufin-O-deethylase (EROD) and glutathione-S-transferase (GST), lipid peroxidation (TBARS) and acetylcholinesterase (AChE)-were measured. Chemical contaminant [polycyclic aromatic hydrocarbons (PAHs), polychlorinated biphenyls (PCBs) and organochlorine pesticides (OCPs)] levels showed different sources of contamination with relatively high concentrations of PAHs in the Hann Bay and Foundiougne locations. The most sensitive biomarker present in different sites according to the principal component analysis is EROD. Few variations of the AChE activity and TBARS levels were found. No clear relationship was found between biomarker responses and salinity, but GR and CF were lower in hypersaline conditions. Tilapia is responsive to environmental contaminants such as PAHs, OCPs and PCBs. The S. melanotheron multiparametric approach showed a better discrimination of sites.

  16. Influence of environmental factors on abundance and temporal variation of benthic fauna resources in the eutrophic Tha Chin estuary, Samut Sakhon province, Thailand.

    PubMed

    Ritnim, Nittaya; Meksumpun, Charumas

    2011-01-01

    The influence of environmental factors on the abundance and temporal variation of benthic fauna resources was studied in the eutrophic Tha Chin estuary located in Samut Sakhon province. The objectives were to analyze the status of abundance and temporal variation of the benthic fauna and to clarify the impacts from environmental factors (water and sediment quality). Field surveys were conducted monthly from August 2007 to March 2008 at 11 sampling stations in the estuary. Based on freshwater runoff volumes, the high-, medium-, and low-loading periods were categorized to be from August to October 2007, November to December 2007, and January to March 2008, respectively. The benthic fauna resources were composed of 57 species in eight phyla. Annelids were the dominant species (with the maximum density being 19,885 individuals/m2), followed by the mollusks. Both densities decreased during the low-loading period in 2008. Water quality deteriorated during the high-loading period. Land-based wastewater discharges decreased the levels of salinity and dissolved oxygen but dramatically increased various nutrients. Consequently, the sediment quality deteriorated during the medium-loading period. Bottom deposits during this time depicted high accumulation of acid volatile sulfides (more than 0.76 mg/g dry weight). Analyzing the environmental relationships, deposit feeders (for example, Nereis sp. and Prionospio sp.) and a clam (Arcuatula sp.) showed potential as bio-indicators for environmental monitoring. The overall results revealed the importance of changes in the water and sediment qualities that had an influence on related benthic resources. The increase in the level of NH4(+)-N had a negative impact on the economic clam species, while the sedimentary TOM showed positive correlation (P < 0.05) with this increase. The succession of groups based on feeding behavior seemed to correspond with stress in eutrophication along the salinity gradient and in different estuarine

  17. Plasticity of gene expression according to salinity in the testis of broodstock and F1 black-chinned tilapia, Sarotherodon melanotheron heudelotii

    PubMed Central

    Guinand, Bruno; Dugué, Rémi; Cosson, Jacky; Legendre, Marc; Panfili, Jacques; Durand, Jean-Dominique

    2014-01-01

    The black-chinned tilapia Sarotherodon melanotheron heudelotii Rüppell 1852 (Teleostei, Cichlidae) displays remarkable acclimation capacities. When exposed to drastic changes of salinity, which can be the case in its natural habitat, it develops quick physiological responses and keeps reproducing. The present study focused on the physiological impact of salinity on male reproductive capacities, using gene expression as a proxy of acclimation process. Two series of experimental fish were investigated: the first one was composed of fish maintained in freshwater for several generations and newly acclimated to salinities of 35 and 70, whereas the second one consisted of the descendants of the latter born and were raised under their native salinity. Expression patterns of 43 candidate genes previously identified from the testes of wild males was investigated in the three salinities and two generations. Twenty of them showed significant expression differences between salinities, and their predicted function revealed that most of them are involved in the osmotic tolerance of sperm cells and/or in the maintenance of sperm motility. A high level of expression variation was evidenced, especially for fish maintained in freshwater. In spite of this, gene expression patterns allowed the differentiation between fish raised in freshwater and those maintained in hypersaline water in both generations. Altogether, the results presented here suggest that this high variability of expression is likely to ensure the reproductive success of this species under varying salinities. PMID:25548735

  18. PAR-2, LGL-1 and the CDC-42 GAP CHIN-1 act in distinct pathways to maintain polarity in the C. elegans embryo.

    PubMed

    Beatty, Alexander; Morton, Diane G; Kemphues, Kenneth

    2013-05-01

    In the one-cell C. elegans embryo, polarity is maintained by mutual antagonism between the anterior cortical proteins PAR-3, PKC-3, PAR-6 and CDC-42, and the posterior cortical proteins PAR-2 and LGL-1 on the posterior cortex. The mechanisms by which these proteins interact to maintain polarity are incompletely understood. In this study, we investigate the interplay among PAR-2, LGL-1, myosin, the anterior PAR proteins and CDC-42. We find that PAR-2 and LGL-1 affect cortical myosin accumulation by different mechanisms. LGL-1 does not directly antagonize the accumulation of cortical myosin and instead plays a role in regulating PAR-6 levels. By contrast, PAR-2 likely has separate roles in regulating cortical myosin accumulation and preventing the expansion of the anterior cortical domain. We also provide evidence that asymmetry of active CDC-42 can be maintained independently of LGL-1 and PAR-2 by a redundant pathway that includes the CDC-42 GAP CHIN-1. Finally, we show that, in addition to its primary role in regulating the size of the anterior cortical domain via its binding to PAR-6, CDC-42 has a secondary role in regulating cortical myosin that is not dependent on PAR-6.

  19. Integration of aquatic ecology and biological oceanographic knowledge for development of area-based eutrophication assessment criteria leading to water resource remediation and utilization management: a case study in Tha Chin, the most eutrophic river of Thailand.

    PubMed

    Meksumpun, Charumas; Meksumpun, Shettapong

    2008-01-01

    This research was carried out in Tha Chin Watershed in the central part of Thailand with attempts to apply multidisciplinary knowledge for understanding ecosystem structure and response to anthropogenic pollution and natural impacts leading to a proposal for an appropriate zonation management approach for sustainable utilization of the area. Water quality status of the Tha Chin River and Estuary had been determined by analyzing ecological, hydrological, and coastal oceanographic information from recent field surveys (during March 2006 to November 2007) together with secondary data on irrigation, land utilization, and socio-economic status.Results indicated that the Tha Chin River and Estuary was eutrophic all year round. Almost 100% of the brackish to marine areas reflected strongly hypertrophic water condition during both dry and high-loading periods. High NH(4)(+) and PO(4)(3-) loads from surrounding agricultural land use, agro-industry, and community continuously flew into the aquatic environment. Deteriorated ecosystem was clearly observed by dramatically low DO levels (ca 1 mg/l) in riverine to coastal areas and Noctiluca and Ceratium red tide outbreaks occurred around tidal front closed to the estuary. Accordingly, fishery resources were significantly decreased. Some riverine benthic habitats became dominated by deposit-feeding worms e.g. Lumbriculus, Branchiura, and Tubifex, while estuarine benthic habitats reflected succession of polychaetes and small bivalves. Results on analysis on integrated ecosystem responses indicated that changing functions were significantly influenced by particulates and nutrients dynamics in the system.Based on the overall results, the Tha Chin River and Estuary should be divided into 4 zones (I: Upper freshwater zone; II: Middle freshwater zone; III Lower freshwater zone; and IV: Lowest brackish to marine zone) for further management schemes on water remediation. In this study, the importance of habitat morphology and water flow

  20. Impacts of nutrients and related environmental factors on distribution and size structure of Noctiluca scintillans populations of the eutrophic Tha Chin estuary, Thailand.

    PubMed

    Chuenniyom, Wansiri; Meksumpun, Charumas; Meksumpun, Shettapong

    2012-01-01

    This study aimed to analyze the impacts of nutrients and related aquatic factors on changes in the Noctiluca population of the Tha Chin estuary, a nutrient-rich estuary located in the inner Gulf of Thailand. Field surveys were carried out at 30 stations during November 2009 to August 2010. The results indicated high levels of dissolved inorganic nitrogen (DIN; 13.89-46.99 μmol/L) and PO(4)(3-)-P (0.20-3.05 μmol/L) where the Noctiluca red tide occurred, particularly during the high-loading period. Dense populations were usually found in the outer part of the estuary with comparatively high salinity (25-29 psu). The highest Noctiluca density was 72,333 cells L(-1) and the cell diameters ranged between 360 and 460 μm. Proportions of small-sized cells (P(s); less than 300 μm) varied over time. In this study, P(s) showed a positive correlation with levels of PO(4)(3-)-P, while the total population density was significantly affected by levels of NH(4)(+)-N and DIN (p < 0.05). Overall, PO(4)(3-)-P influenced the development of the Noctiluca red tide, with the limitation of PO(4)(3-)-P levels to below 1 μmol/L suggested for controlling Noctiluca red tide outbreaks at their origin. To support environmental conservation and maintain sustainable production in the estuary, the levels of PO(4)(3-)-P should be considered for the further effective development of water quality standards in estuarine zones.

  1. An Atmospheric Pressure Ping-Pong "Ballometer"

    ERIC Educational Resources Information Center

    Kazachkov, Alexander; Kryuchkov, Dmitriy; Willis, Courtney; Moore, John C.

    2006-01-01

    Classroom experiments on atmospheric pressure focus largely on demonstrating its existence, often in a most impressive way. A series of amusing physics demonstrations is widely known and practiced by educators teaching the topic. However, measuring the value of atmospheric pressure(P[subscript atm]) is generally done in a rather mundane way,…

  2. Vertical Ridge Augmentation of the Atrophic Posterior Mandible with Sandwich Technique: Bone Block from the Chin Area versus Corticocancellous Bone Block Allograft—Clinical and Histological Prospective Randomized Controlled Study

    PubMed Central

    Laino, Luigi; Piattelli, Adriano; Lo Muzio, Lorenzo

    2014-01-01

    The aim of the present study is to compare the histological aspects of bone formation in atrophic posterior mandibles augmented by autologous bone block from chin area with corticocancellous bone block allograft used as inlays with the sandwich technique. Materials and Methods. Sixteen patients with bilateral partial edentulism in the posterior mandible were selected. The residual bone height, preliminarily measured by computed tomography scans, ranged between 5 and 7 mm from the inferior alveolar nerve. All patients required regeneration procedure with autologous bone block from chin area (control group) versus bone block allograft Puros (Zimmer Dental, 1900 Aston Avenue, Carlsbad, CA, USA) (test group). Histological and histomorphometric samples were collected at the time of implant positioning in order to analyze the percentage of newly formed bone, the residual graft material, and marrow spaces/soft tissue. Results. No statistically significant differences between the two groups were found regarding the percentage of newly formed bone. The percentage of residual grafted material was significantly higher in the test group, whilst the percentage of marrow spaces was higher in control group. Conclusions. In conclusion, both procedures supported good results, although the use of bone blocks allograft was less invasive and preferable than harvesting bone from the mental symphysis. PMID:24877155

  3. Ping-pong modes: a new form of multipactor.

    PubMed

    Kishek, R A

    2012-01-20

    The multipactor is a vacuum discharge based on a secondary electron emission. A novel resonant form is proposed that combines one- and two-surface impacts within a single period, provided the total transit time is an odd number of rf half-periods and the product of secondary yields exceeds unity. For low fD products, the simplest such mode is shown to significantly increase the upper electric field boundary of the multipacting region and lead to overlap of higher-order bands. The results agree nicely with 3D particle-in-cell code simulations. Practical implications of the findings are discussed.

  4. From Pong to Pokemon Go, catching the essence of the Internet Gaming Disorder diagnosis.

    PubMed

    Carbonell, Xavier

    2017-03-17

    Taking as a starting point, this commentary proposes some issues regarding the diagnosis of Internet Gaming Disorder discussed in Kuss et al. (2016). In our opinion, the confusion in DSM-5 diagnosis could be due to the weak starting point in building the criteria. The criteria such as functional impairment and stability of the dysfunctional behavior are considered. It is suggested that avatar identification, playing motivations, and types of video games should be considered for diagnosis. The diagnostic process is highly influenced by social context and the rapid development of video game industry. The commentary ends by considering the distinction between online and offline video gaming and the critical consideration of everyday behaviors as being addictive.

  5. Security of modified Ping-Pong protocol in noisy and lossy channel

    PubMed Central

    Han, Yun-Guang; Yin, Zhen-Qiang; Li, Hong-Wei; Chen, Wei; Wang, Shuang; Guo, Guang-Can; Han, Zheng-Fu

    2014-01-01

    The “Ping-Pong” (PP) protocol is a two-way quantum key protocol based on entanglement. In this protocol, Bob prepares one maximally entangled pair of qubits, and sends one qubit to Alice. Then, Alice performs some necessary operations on this qubit and sends it back to Bob. Although this protocol was proposed in 2002, its security in the noisy and lossy channel has not been proven. In this report, we add a simple and experimentally feasible modification to the original PP protocol, and prove the security of this modified PP protocol against collective attacks when the noisy and lossy channel is taken into account. Simulation results show that our protocol is practical. PMID:24816899

  6. Giant Dielectric Permittivity in Ferroelectric Thin Films: Domain Wall Ping Pong

    PubMed Central

    Quan Jiang, An; Jian Meng, Xiang; Wei Zhang, David; Hyuk Park, Min; Yoo, Sijung; Jin Kim, Yu; Scott, James F.; Seong Hwang, Cheol

    2015-01-01

    The dielectric permittivity in ferroelectric thin films is generally orders of magnitude smaller than in their bulk. Here, we discover a way of increasing dielectric constants in ferroelectric thin films by ca. 500% by synchronizing the pulsed switching fields with the intrinsic switching time (nucleation of domain plus forward growth from cathode to anode). In a 170-nm lead zirconate titanate thin film with an average grain size of 850 nm this produces a dielectric constant of 8200 with the maximum nucleus density of 3.8 μm−2, which is one to three orders of magnitude higher than in other dielectric thin films. This permits smaller capacitors in memory devices and is a step forward in making ferroelectric domain-engineered nano-electronics. PMID:26440528

  7. Ping Pong: Competing Leadership for Reform in EU Higher Education 1998-2006

    ERIC Educational Resources Information Center

    Corbett, Anne

    2011-01-01

    How effective is EU cooperation in higher education? This article treats the issue as one of effectiveness in policy-making. What are the policy ideas which the EU wishes to feed into a policy domain where it has to operate largely through political cooperation and a modest degree of incentive funding? What outcomes are possible? The question is…

  8. "Verbal Ping Pong" as Culturally Congruent Communication: Maximizing African American Students' Access and Engagement as Socially Just Teaching

    ERIC Educational Resources Information Center

    Carpenter Ford, Amy

    2013-01-01

    African American youth have been disciplined and dismissed from classrooms for engaging in culturally-based communication practices that teachers misinterpret and perceive as disruptive. Teachers have significant power in how they communicate with their students. White teachers should be especially aware of this power because misunderstandings…

  9. One Loop to Rule Them All: The Ping-Pong Cycle and piRNA-Guided Silencing

    PubMed Central

    Czech, Benjamin; Hannon, Gregory J.

    2016-01-01

    The PIWI-interacting RNA (piRNA) pathway is a conserved defense mechanism that protects the genetic information of animal germ cells from the deleterious effects of molecular parasites, such as transposons. Discovered nearly a decade ago, this small RNA silencing system comprises PIWI-clade Argonaute proteins and their associated RNA-binding partners, the piRNAs. In this review, we highlight recent work that has advanced our understanding of how piRNAs preserve genome integrity across generations. We discuss the mechanism of piRNA biogenesis, give an overview of common themes as well as differences in piRNA-mediated silencing between species, and end by highlighting known and emerging functions of piRNAs. PMID:26810602

  10. Ping-Pong, Endurance, Card and other Types of Drinking Games: Are These Games of the Same Feather?

    ERIC Educational Resources Information Center

    Zamboanga, Byron L.; Calvert, Barbara D.; O'Riordan, Siobhan S.; McCollum, Elan C.

    2007-01-01

    The goal of this study was to investigate the structural heterogeneity of drinking games with respect to beverage type consumed, competitiveness, intoxication level, and game duration, as well as the motives for participation in different games and their relevance to intoxication level while playing. Participants were female students ( N = 162; M…

  11. Transcriptional responses of the black-chinned tilapia Sarotherodon melanotheron to salinity extremes.

    PubMed

    Tine, Mbaye; de Lorgeril, Julien; D'Cotta, Hélèna; Pepey, Elodie; Bonhomme, François; Baroiller, Jean François; Durand, Jean-Dominique

    2008-06-01

    Sarotherodon melanotheron is one of the most euryhaline teleosts able to withstand variations in environmental salinity ranging from freshwater (FW) to 130‰ hyper-saline waters (HSW). Although significant progress has been made in exploring the cellular and molecular changes that accompany salinity adaptation in teleosts, little is known about the effects of long-term acclimation to HSW. We sought to identify in this tilapia species the genes whose transcription is induced by long-term acclimation either to HSW or FW. Two subtractive cDNA libraries were made from gills of fish acclimated for 45 days to either condition, with 320 partial cDNA sequences encoding proteins potentially involved in the response to the two salinity extremes. The ESTs comparisons with genomic databases allowed putative functions to be attributed to 197 of these genes. The suppression subtractive hybridisation (SSH) results were validated by Real-time PCR for 13 candidate genes having presumably a role in osmoregulation, supplemented by Na(+), K(+)-ATPase α-subunit and carbonic anhydrase, two genes known to be implicated in this function. In fish acclimated to both salinity extremes, the functional category of cellular process was the predominant one, which may indicate high cellular turnover rates in FW and HSW-adapted fish. The acclimation to FW and HSW also appeared to trigger the expression of genes involved in transport activity, biological regulation and metabolic processes, at a higher level in fish acclimated to HSW, suggesting higher metabolic activity in this situation. These results are a first step towards the identification of key molecular processes involved in the fish acclimation to extreme salinities.

  12. "The Source of Learning Is Thought" Reading the "Chin-ssu lu" (???) with a "Western Eye"

    ERIC Educational Resources Information Center

    Reichenbach, Roland

    2016-01-01

    The contribution focuses on Neo-Confucian texts as collected by Zhu Xi (?? 1130-1200) and Lü Zuqian (1137-1181) and is a look from the "outside", from the perspective of German theories of Bildung ("self-cultivation"). It aims at demonstrating that among other insights that today's readers may gather from Neo-Confucian…

  13. VizieR Online Data Catalog: Interstellar S isotopes (Chin+, 1996)

    NASA Astrophysics Data System (ADS)

    Chin, Y.-N.; Henkel, C.; Whiteoak, J. B.; Langer, N.; Churchwell, E. B.

    1995-09-01

    A 12C32S, 13C32S, 12 has been made to study interstellar 32S/34S and 34S/33S ratios from the galactic disk. The four CS isotopomers were detected in 20 star forming regions with galactocentric distances between 3 and 9kpc. From a comparison of line velocities, the C33S J=2-1 rest frequency is ~250kHz below the value given in the Lovas (1992) catalog. Taking 12C/13C ratios from Wilson & Rood (1994) and assuming equal 12C32S and 13C32S excitation temperatures and beam filling factors, 12C32S opacities are in the range 3 to 15; average 32S/34S and 34S/33S isotope ratios are 24.4+/-5.0 and 6.27+/-1.01, respectively. While no systematic variation in the 34S/33S isotope ratio is found, the 32S/34S ratio increases with galactocentric distance when accounting for the 12C/13C gradient of the galactic disk. A fit to the unweighted data yields 32S/34S=3.3+/-0.5(DGC/kpc)+4.1+/-3.1 with a correlation coefficient of 0.84. Since the interstellar sulfur (S) isotopes are synthesized by oxygen burning in massive stars, consequences for nucleosynthesis and models of chemical evolution are briefly discussed. (1 data file).

  14. Chin Prompt Plus Re-Presentation as Treatment for Expulsion in Children with Feeding Disorders

    ERIC Educational Resources Information Center

    Wilkins, Jonathan W.; Piazza, Cathleen C.; Groff, Rebecca A.; Vaz, Petula C. M.

    2011-01-01

    Expulsion (spitting out food) is a problem behavior observed in many children with feeding disorders. In the current investigation, we identified 4 children diagnosed with a feeding disorder who exhibited high rates of expulsion. Treatment with re-presentation (placing expelled liquids or solids back into the child's mouth) was not effective in…

  15. Maxillary, mandibular, and chin advancement: treatment planning based on airway anatomy in obstructive sleep apnea.

    PubMed

    Schendel, Stephen; Powell, Nelson; Jacobson, Richard

    2011-03-01

    Surgical correction of obstructive sleep apnea (OSA) syndrome involves understanding a number of parameters, of which the 3-dimensional airway anatomy is important. Visualization of the upper airway based on cone beam computed tomography scans and automated computer analysis is an aid in understanding normal and abnormal airway conditions and their response to surgery. The goal of surgical treatment of OSA syndrome is to enlarge the velo-oropharyngeal airway by anterior/lateral displacement of the soft tissues and musculature by maxillary, mandibular, and possibly, genioglossus advancement. Knowledge of the specific airway obstruction and characteristics based on 3-dimensional studies permits a directed surgical treatment plan that can successfully address the area or areas of airway obstruction. The end occlusal result can be improved when orthodontic treatment is combined with the surgical plan. The individual with OSA, though, is more complicated than the usual orthognathic patient, and both the medical condition and treatment length need to be judiciously managed when OSA and associated conditions are present. The perioperative management of the patient with OSA is more complex and the margin for error is reduced, and this needs to be taken into consideration and the care altered as indicated.

  16. Holocene left-slip rate determined by cosmogenic surface dating on the Xidatan segment of the Kunlun Fault (Qinghai, Chin

    SciTech Connect

    Guoguang, Z; Caffee, M; Finkel, R; G,; demer, Y; Meriaux, A S; Qunlu,; Ryerson, F J; Tapponnier, P; Van der Woerd, J

    1998-09-01

    Cosmogenic dating, using in-situ 26A1 and 10Be in quartz pebbles from alluvial terrace surfaces, constrains the late Holocene slip rate on the Xidatan segment of the Kuniun fault in northeastern Tibet. Two terrace risers offset by 24 ± 3 and 33 f± 4m, having respective ages of 1788 ± 388 and 2914 ± 471 yr, imply a slip rate of 12.1 ± 2.6 mm/yr. The full range of ages obtained ((less than or equal to) 22.8 k.y., most of them between 6.7 and 1.4 k.y.) confirm that terrace deposition and incision, hence landform evolution, are modulated by post-glacial climate change. Coupled with minimum offsets of 9-12 m, this slip rate implies that great earthquakes (M-8) with a recurrence time of 800-1000 yr. rupture the Kunlun fault n

  17. 68Ga PSMA PET/CT in a Rare Case of Metastatic Adenocarcinoma Prostate Presenting as Numb Chin Syndrome.

    PubMed

    Sasikumar, Arun; Joy, Ajith; Pillai, M R A; Gopal, Renuka; Thomas, Boben

    2017-03-01

    A 68-year-old man presented with right-side facial numbness. MRI showed an extra-axial mass infiltrating the right temporal bone. It was debulked surgically, and histopathology revealed metastatic adenocarcinoma. Ga PSMA PET/CT done in view of increased PSA levels and clinically suspicious hard lesion in prostate showed primary lesion in left side of prostate with metastases to the right temporal bone. Primary carcinoma of the prostate and metastases to the right temporal bone were proven histopathologically. Our case highlights the usefulness of Ga PSMA PET/CT in identifying the primary site in suspected prostate cancer and mapping the metastatic sites.

  18. Garnet-pyroxene-amphibole xenoliths from Chin Valley, Arizona, and implications for continental lithosphere below the Moho

    NASA Astrophysics Data System (ADS)

    Smith, Douglas; Arculus, Richard J.; Manchester, Janet E.; Tyner, G. Nell

    1994-01-01

    Garnet-pyroxene-amphibole xenoliths illustrate how P and T histories can be recorded in rocks from the crust-mantle transition and document the diversity of continental lithosphere below the Mohorovicic discontinuity. The xenoliths are from the Sullivan Buttes Latite in Chino Valley, Arizona, in the Transition Zone of the Colorado Plateau. The most definitive depth assignments depend upon garnet-pyroxene thermobarometry coupled with analysis of Ca and Al gradients in orthopyroxene. Websterites that record temperatures of 600-700C contain orthopyroxene zoned in Al but not Ca, and these rocks were carried up from depths of at least 43 km. Websterites that record temperatures of 800-900C contain more homogeneous orthopyroxene, and they were erupted from 70 to 80 km. Most eclogite and amphibole-rich xenoliths record temperatures in the range bracketed by websterites and so were probably erupted from similar depths. Element abundances and Sr, Nd, and Pb isotope ratios establish that protoliths of most xenoliths formed by crystal-melt fractionation from basaltic magmas. Diverse Sr and Nd isotopic compositions range from Nd-epsilon approximately equals +8 and Sr-87/Sr-86 approximately equals 0.7045 for two websterites to Nd-epsilon approximately equals -9 and Sr-87/Sr-86 approximately equals 0.7064 for both parts of a composite eclogite. Most xenoliths probably have Proterozoic protoliths, although many record more recent thermal and metasomatic events, and a few probably formed from Cenozoic magmas. Observations are consistent with a reconstruction of the lithosphere in which eclogite and amphibole-rich rock were volumetrically important to depths of at least 70-80 km at 25 Ma. Anhydrous peridotite may not dominate just below the Mohorovicic discountinuity beneath Chino Valley or beneath some other localities on the Colorado Plateau and elsewhere. No evidence was observed in the Chino Valley suite for replacement of continental lithosphere during Phanerozic tectonism or for significant underplating in Cenozoic time.

  19. Long-standing chin-augmenting costochondral graft creating a diagnostic challenge: A case report and literature review

    PubMed Central

    Mintline, Mark; Ruprecht, Axel; Cohen, Donald; Blumberg, Barton R.; Nair, Madhu K.

    2016-01-01

    To our knowledge, the imaging features of costochondral grafts (CCGs) on cone-beam computed tomography (CBCT) have not been documented in the literature. We present the case of a CCG in the facial soft tissue to the anterior mandible, with changes mimicking a cartilaginous neoplasm. This is the first report to describe the CBCT imaging features of a long-standing graft in the anterior mandible. Implants or grafts may be incidental findings on radiographic images made for unrelated purposes. Although most are well-defined and radiographically homogeneous, being of relatively inert non-biological material, immune reactions to some grafts may stimulate alterations in the appearance of surrounding tissues. Biological implants may undergo growth and differentiation, causing their appearance to mimic neoplastic lesions. We present the case of a cosmetic autogenous CCG that posed a diagnostic challenge both radiographically and histopathologically. PMID:28035307

  20. Salinity-related variation in gene expression in wild populations of the black-chinned tilapia from various West African coastal marine, estuarine and freshwater habitats

    NASA Astrophysics Data System (ADS)

    Tine, Mbaye; McKenzie, David J.; Bonhomme, François; Durand, Jean-Dominique

    2011-01-01

    This study measured the relative expression of the genes coding for Na +, K +-ATPase 1α(NAKA), voltage-dependent anion channel (VDAC), cytochrome c oxidase-1 (COX), and NADH dehydrogenase (NDH), in gills of six wild populations of a West African tilapia species, acclimatised to a range of seasonal (rainy or dry) salinities in coastal, estuarine and freshwater sites. Previous laboratory experiments have demonstrated that these genes, involved in active ion transport, oxidative phosphorylation, and intra-cellular ATP transport, are relatively over-expressed in gill tissues of this species acclimated to high salinity. Positive correlations between relative expression and ambient salinity were found for all genes in the wild populations (Spearman rank correlation, p < 0.05), although for some genes these were only significant in either the rainy season or dry season. Most significantly, however, relative expression was positively correlated amongst the four genes, indicating that they are functionally interrelated in adaptation of Sarotherodon melanotheron to salinity variations in its natural environment. In the rainy season, when salinity was unstable and ranged between zero and 37 psu across the sites, overall mean expression of the genes was higher than in the dry season, which may have reflected more variable particularly sudden fluctuations in salinity and poorer overall water quality. In the dry season, when the salinity is more stable but ranged between zero and 100 psu across the sites, NAKA, NDH and VDAC expression revealed U-shaped relationships with lowest relative expression at salinities approaching seawater, between 25 and 45 psu. Although it is not simple to establish direct relationship between gene expression levels and energy requirement for osmoregulation, these results may indicate that costs of adaptation to salinity are lowest in seawater, the natural environment of this species. While S. melanotheron can colonise environments with extremely high salinities, up to 100 psu, this was related to high relative expression for all genes studied, indicating that this imposes increased energy demand for osmotic homeostasis in gill tissues. This study is the first to demonstrate, in fish and in wild populations, that expression of NAKA, VDAC, NDH and COX are interrelated in gill tissues, and are involved in long-term acclimatisation to a salinity range between 0 and 100 psu.

  1. The impact of environmental degradation on reproduction of the black-chinned tilapia Sarotherodon melanotheron from various coastal marine, estuarine and freshwater habitats.

    PubMed

    Guèye, Moussa; Kantoussan, Justin; Tine, Mbaye

    2013-07-01

    There is growing evidence that climate change has greatly altered environmental conditions in many aquatic ecosystems over the last decades, leading to changes in fish distribution and life history traits. Recent works conducted in Senegalese and Gambian coastal marine, estuarine and freshwater ecosystems have shown important changes in the intensity, frequency and breeding timing of wild population of Sarotherodon melanotheron in response to changes in salinity regimes. In addition to salinity, this study investigates the potential influences of other environmental factors that have received less attention on the reproduction of S. melanotheron from three different aquatic ecosystems in Senegal. The results demonstrate that day-length and temperature affect sexual maturity in both males and females from Guiers Lake and Hann Bay, but no such effects were found in upstream of the Saloum Estuary, where the spawning activity seems to be under the synergetic control of rainfall and salinity that apparently predominate over all the other ambient factors. This study demonstrated for the first time that aside from photoperiod and temperature, rainfall also influences fish reproduction in Hann Bay probably through its effects on water quality. Furthermore, our results confirm previous findings that changes in salinity regimes resulting from seasonal variations in precipitation and evaporation are the ultimate causes of temporal changes in the reproductive activity of the species in this estuary.

  2. The Forty-Eight-Hour Rule: Emotional Engagement and the Student Athlete

    ERIC Educational Resources Information Center

    Mueller, Alan C. R.

    2009-01-01

    Several years ago, the author taught a course called First-Year experience. A student named Sean mentioned that he played "water pong." Sean, a high-achieving student who was also a member of the lacrosse team, explained that water pong was a game with the rules of beer pong, using water rather than beer. Sean volunteered an explanation of his…

  3. Assessing the Effectiveness of Gravitational Wave Outreach Video Games in High School Students

    NASA Astrophysics Data System (ADS)

    Wheeler, Jonathan

    Students and faculty at the Gravitational Wave Group in Birmingham, UK developed a remake of the classic 1972 game of Pong. Black Hole Pong was developed to be used in events such as science fairs as a way to engage children and pique interest in black holes. I present the results of a study which assesses the utility of Black Hole Pong and its successors in raising awareness of gravitational wave research, and in fostering conceptual understanding of astrophysics and gravity. Of particular interest in this study is potential use in high school science classrooms during astrophysics units.

  4. Deoxycholic Acid Injection

    MedlinePlus

    Deoxycholic acid injection is used to improve the appearance and profile of moderate to severe submental fat ('double chin'; fatty tissue located under the chin). Deoxycholic acid injection is in a class of medications called ...

  5. Applying Human Capital Management to Model Manpower Readiness: A Conceptual Framework

    DTIC Science & Technology

    2005-12-01

    CAPITAL MANAGEMENT TO MODEL MANPOWER READINESS: A CONCEPTUAL FRAMEWORK by Pert Chin Ngin December 2005 Associate Advisors: William R...Management to Model Manpower Readiness: A Conceptual Framework 6. AUTHOR(S) Pert Chin Ngin 5. FUNDING NUMBERS 7. PERFORMING ORGANIZATION NAME(S...distribution is unlimited. APPLYING HUMAN CAPITAL MANAGEMENT TO MODEL MANPOWER READINESS: A CONCEPTUAL FRAMEWORK Pert Chin Ngin MAJOR, Republic of

  6. Complete Genome Sequences of Six Chrysodeixis includens Nucleopolyhedrovirus Isolates from Brazil and Guatemala

    PubMed Central

    Craveiro, Saluana R.; Santos, Luis Arthur V. M.; Togawa, Roberto C.; Inglis, Peter W.; Grynberg, Priscila; Ribeiro, Zilda Maria A.; Ribeiro, Bergmann M.

    2016-01-01

    The baculovirus, Chrysodeixis (formerly Pseudoplusia) includens nucleopolyhedrovirus (ChinNPV), is a new Alphabaculovirus pathogenic to Chrysodeixis includens. Here, we report the complete genome sequences of six ChinNPV isolates. The availability of these genome sequences will provide information on ChinNPV molecular genetics, promoting understanding of its pathogenicity, diversity, and evolution. PMID:27932639

  7. Closing the Gap Between Research and Field Applications for Multi-UAV Cooperative Missions

    DTIC Science & Technology

    2013-09-01

    BETWEEN RESEARCH AND FIELD APPLICATIONS FOR MULTI-UAV COOPERATIVE MISSIONS by Harn Chin Teo September 2013 Thesis Co-Advisors: Oleg...APPLICATIONS FOR MULTI-UAV COOPERATIVE MISSIONS 5. FUNDING NUMBERS 6. AUTHOR(S) Harn Chin Teo 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES...MISSIONS Harn Chin Teo Systems Engineer, ST Aerospace Ltd. B.E., Nanyang Technological University (Singapore), 2008 Submitted in partial

  8. North Korea: A Government-Sponsored Drug Trafficking Network

    DTIC Science & Technology

    2006-01-01

    some hasty repair work, the HMAS Stuart set out to capture the Pong Su. In the Tasman Sea on April 19, after the Stuart clearly identified the Pong...coast. Following the arrests civil police intercepted the ship but they were unable to board due to heavy seas . The Navy had to be summoned. After...of Chongjin, a large port city on North Korea’s northeast coast. “I’d pick it up and drive it to the harbor, and it would be taken out to sea to be

  9. 77 FR 11575 - Notice of Inventory Completion: Grand Rapids Public Museum, Grand Rapids, MI

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-27

    ... of Arizona on behalf of themselves and the Ak Chin Indian Community of the Maricopa (Ak Chin) Indian Reservation, Arizona; Gila River Indian Community of the Gila River Indian Reservation, Arizona; and the Salt River Pima-Maricopa Indian Community of the Salt River Reservation, Arizona. The Zuni Tribe of the...

  10. 77 FR 11571 - Notice of Intent To Repatriate Cultural Items: Fowler Museum at UCLA, Los Angeles, CA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-27

    ..., most of which are now on the Gila River Indian Reservation, AZ. The Gila River Indian Community of the... described in this notice, on behalf of itself and the Ak Chin Indian Community of the Maricopa (Ak Chin) Indian Reservation, Arizona; Salt River Pima-Maricopa Indian Community of the Salt River...

  11. The Scholarship of Teaching and Learning in Teaching Sociology: 1973-2009

    ERIC Educational Resources Information Center

    Paino, Maria; Blankenship, Chastity; Grauerholz, Liz; Chin, Jeffrey

    2012-01-01

    This article updates and extends research by Baker and Chin, who tracked changes in studies published in Teaching Sociology from 1973 to 1983 (Baker) and 1984 to 1999 (Chin). The current study traces manuscripts published in "Teaching Sociology" from 2000 to 2009. We examine both who publishes in the journal and what gets published. In particular,…

  12. Topical Rapamycin Therapy to Alleviate Cutaneous Manifestations of Tuberous Sclerosis Complex

    DTIC Science & Technology

    2015-05-01

    or pink papules distributed over the central face, especially on the nasolabial folds, cheeks, and chin. Lesions appear in early childhood and are...cheeks, and chin. Lesions appear in early childhood and are present in up to 80% of TSC patients. These facial lesions create considerable cosmetic

  13. 75 FR 43199 - Alaska Native Claims Selection

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-23

    ... approving the conveyance of surface estate for certain lands to Beaver Kwit'chin Corporation, pursuant to... Doyon, Limited when the surface estate is conveyed to Beaver Kwit'chin Corporation. The lands are in the vicinity of Beaver, Alaska, and are located in: Fairbanks Meridian, Alaska T. 16 N., R. 1 E., Secs. 1 to...

  14. Recoil Experiments Using a Compressed Air Cannon

    ERIC Educational Resources Information Center

    Taylor, Brett

    2006-01-01

    Ping-Pong vacuum cannons, potato guns, and compressed air cannons are popular and dramatic demonstrations for lecture and lab. Students enjoy them for the spectacle, but they can also be used effectively to teach physics. Recently we have used a student-built compressed air cannon as a laboratory activity to investigate impulse, conservation of…

  15. Sequence and properties of pentaerythritol tetranitrate reductase from Enterobacter cloacae PB2.

    PubMed

    French, C E; Nicklin, S; Bruce, N C

    1996-11-01

    Pentaerythritol tetranitrate reductase, which reductively liberates nitrite from nitrate esters, is related to old yellow enzyme. Pentaerythritol tetranitrate reductase follows a ping-pong mechanism with competitive substrate inhibition by NADPH, is strongly inhibited by steroids, and is capable of reducing the unsaturated bond of 2-cyclohexen-1-one.

  16. The Stair-Step Atom.

    ERIC Educational Resources Information Center

    Jordan, Thomas M.; And Others

    1992-01-01

    Presents a model of a generic atom that is used to represent the movement of electrons from lower to higher levels and vice-versa due to excitation and de-excitation of the atom. As the process of de-excitation takes place, photons represented by colored ping-pong balls are emitted, indicating the emission of light. (MDH)

  17. Apparatus Notes.

    ERIC Educational Resources Information Center

    Eaton, Bruce G., Ed.

    1980-01-01

    This collection of notes describes (1) an optoelectronic apparatus for classroom demonstrations of mechanical laws, (2) a more efficient method for demonstrated nuclear chain reactions using electrically energized "traps" and ping-pong balls, and (3) an inexpensive demonstration for qualitative analysis of temperature-dependent resistance. (CS)

  18. Contribution of Race, Primary Language, Family Structure and Pre-Kindergarten Attendance to the Odds of Being Classified as Having a Specific Learning Disability by the Third Grade

    ERIC Educational Resources Information Center

    Roring, Catherine Mary

    2013-01-01

    Many risk factors have been identified for children entering Kindergarten. Many at-risk children eventually get classified as having a Specific Learning disability. Some of these risk factors include having a primary home language other than English (Hosp & Reschly, 2004), having non-intact families (Pong, 1997), being of minority status…

  19. Games People Play

    ERIC Educational Resources Information Center

    VerBruggen, Robert

    2012-01-01

    Today's video games aren't even a little bit like the ones that came out a few decades ago. Not only has the underlying technology dramatically improved, but the medium has matured remarkably in the years since "Pong" and "Space Invaders." ruled the arcades. The artistic promise of video games has yet to be fulfilled. The current state of the…

  20. Assessing Uncertainties in a Simple and Cheap Experiment

    ERIC Educational Resources Information Center

    de Souza, Paulo A., Jr.; Brasil, Gutemberg Hespanha

    2009-01-01

    This paper describes how to calculate measurement uncertainties using as a practical example the assessment of the thickness of ping-pong balls and their material density. The advantages of a randomized experiment are also discussed. This experiment can be reproduced in the physics laboratory for undergraduate students. (Contains 7 tables, 1…

  1. RNA helicase Spn-E is required to maintain Aub and AGO3 protein levels for piRNA silencing in the germline of Drosophila.

    PubMed

    Ryazansky, Sergei S; Kotov, Alexei A; Kibanov, Mikhail V; Akulenko, Natalia V; Korbut, Alina P; Lavrov, Sergei A; Gvozdev, Vladimir A; Olenina, Ludmila V

    2016-09-01

    Germline-specific RNA helicase Spindle-E (Spn-E) is known to be essential for piRNA silencing in Drosophila that takes place mainly in the perinuclear nuage granules. Loss-of-function spn-E mutations lead to tandem Stellate genes derepression in the testes and retrotransposon mobilization in the ovaries. However, Spn-E functions in the piRNA pathway are still obscure. Analysis of total library of short RNAs from the testes of spn-E heterozygous flies revealed the presence of abundant piRNA ping-pong pairs originating from Su(Ste) transcripts. The abundance of these ping-pong pairs were sharply reduced in the library from the testes of spn-E mutants. Thus we found that ping-pong mechanism contributed to Su(Ste) piRNA generation in the testes. The lack of Spn-E caused a significant drop of protein levels of key ping-pong participants, Aubergine (Aub) and AGO3 proteins of PIWI subfamily, in the germline of both males and females, but did not disrupt of their assembly in nuage granules. We found that observed decline of the protein expression was not caused by suppression of aub and ago3 transcription as well as total transcription, indicating possible contribution of Spn-E to post-transcriptional regulation.

  2. These Kids Are Really on the Ball! Invention Competition Winners

    ERIC Educational Resources Information Center

    Tech Directions, 2008

    2008-01-01

    Judge Harry T. Roman, an electrical engineer and inventor himself, has selected the best entries in the 2007-2008 "Tech Directions" Inventors Award Competition. This year's challenge called for students to devise new uses for the common Ping-Pong ball. Of the results, the judge notes "The ideas submitted were most interesting, with a high number…

  3. Tricky Circuitry

    ERIC Educational Resources Information Center

    Davies, Tony

    2014-01-01

    Teaching children about circuits and the way electricity works is a "tricky business" because it is invisible. Just imagine all eyes are on the teacher as he or she produces for the class what looks like a ping-pong ball and then, with a wave of their hand, the incredible happens! This wonderful white sphere begins to glow red and a…

  4. How to Act? a Question of Encapsulating Infinity

    ERIC Educational Resources Information Center

    Mamolo, Ami

    2014-01-01

    This article investigates some of the specific features involved in accommodating the idea of actual infinity as it appears in set theory. It focuses on the conceptions of two individuals with sophisticated mathematics background, as manifested in their engagement with variations of a well-known paradox: the ping-pong ball conundrum. The APOS…

  5. Kick Stick Hands-on Challenge: Discover Circuits with PBS's "Design Squad Nation"[TM

    ERIC Educational Resources Information Center

    Feinberg, Lauren

    2011-01-01

    This article describes the "Kick Stick" activity from Design Squad Nation, in which kids turn a wooden paint stirrer and circuit into a motorized, spinning arm--then use it to kick a Ping-Pong[R] ball across the floor. Teachers can enrich their students' exploration of circuits and emphasize the engineering design process with "Design Squad…

  6. Academic Value of Non-Academics: The Case for Keeping Extracurriculars

    ERIC Educational Resources Information Center

    Kronholz, June

    2012-01-01

    With school districts struggling to keep their noses above choppy budget waters and voters howling about taxes, should schools be funding Ping-Pong and trading-card clubs? Swim teams, moot court, powder puff football? Latino unions, gay-straight alliances, the Future Business Leaders of America, the French Honors Society, the jazz band, the…

  7. The Effect of Recreational Activities on Self-Esteem Development of Girls in Adolescence

    ERIC Educational Resources Information Center

    Bayazit, Betül

    2014-01-01

    This study aimed to investigate the effect of recreational activities on self-esteem development of girls in adolescence. For this purpose, a total of 20 girls in adolescence period took part in the present study. Recreational activities program included bowling, patenga, orienteering, basketball, volleyball, badminton, ping-pong, dance, fun…

  8. X Marks the Spot: Creating and Managing a Single Service Point to Improve Customer Service and Maximize Resources

    ERIC Educational Resources Information Center

    Venner, Mary Ann; Keshmiripour, Seti

    2016-01-01

    This article will describe how merging service points in an academic library is an opportunity to improve customer service and utilize staffing resources more efficiently. Combining service points provides libraries with the ability to create a more positive library experience for patrons by minimizing the ping-pong effect for assistance. The…

  9. Classroom Games in the Compulsory School

    ERIC Educational Resources Information Center

    Kraus-Serbic, Eva

    1976-01-01

    Keeping the pupils' interest up throughout the year in a compulsory language class is a major problem and therefore, language-teaching games are very important. Some new suggestions for games to be used in the elementary school are: (1) The Parrot; (2) The Robot; (3) Ping-Pong; and (4) Telephone. Card games such as Happy Families can be played…

  10. Ikons for Mathematics, Part I. Problem Solving and Strategy Games.

    ERIC Educational Resources Information Center

    Melrose, Jean; Rowe, Susan

    1989-01-01

    Described are some designs in the playground of an infant school, and indicated are some mathematical activities that resulted from their use. Games included are Schlegel diagram of Dodecahedron, Pong Hau K'i, Ko No, Achi, Draughts, and Star with their diagrams. (YP)

  11. Action-Specific Effects in a Social Context: Others' Abilities Influence Perceived Speed

    ERIC Educational Resources Information Center

    Witt, Jessica K.; Sugovic, Mila; Taylor, J. Eric T.

    2012-01-01

    According to the action-specific account of perception, perceivers see the environment relative to their ability to perform the intended action. For example, in a modified version of the computer game Pong, balls that were easier to block looked to be moving slower than balls that were more difficult to block (Witt & Sugovic, 2010). It is unknown,…

  12. Does Ease to Block a Ball Affect Perceived Ball Speed? Examination of Alternative Hypotheses

    ERIC Educational Resources Information Center

    Witt, Jessica K.; Sugovic, Mila

    2012-01-01

    According to an action-specific account of perception, the perceived speed of a ball can be a function of the ease to block the ball. Balls that are easier to stop look like they are moving slower than balls that are more difficult to stop. This was recently demonstrated with a modified version of the classic computer game Pong (Witt & Sugovic,…

  13. The Analog Atomic Force Microscope: Measuring, Modeling, and Graphing for Middle School

    ERIC Educational Resources Information Center

    Goss, Valerie; Brandt, Sharon; Lieberman, Marya

    2013-01-01

    using an analog atomic force microscope (A-AFM) made from a cardboard box and mailing tubes. Varying numbers of ping pong balls inside the tubes mimic atoms on a surface. Students use a dowel to make macroscale measurements similar to those of a nanoscale AFM tip as it…

  14. Filling in the Gaps: Modelling Incomplete CBL Data Using a Graphing Calculator.

    ERIC Educational Resources Information Center

    Swingle, David A.; Pachnowski, Lynne M.

    2003-01-01

    Discusses a real-world problem-solving lesson that emerged when a high school math teacher used a motion detector with a CBL and graphing calculator to obtain the bounce data of a ping-pong ball. Describes the lesson in which students collect bad data then fill in the missing parabolas that result using critical components of parabolas and…

  15. "Speak Out. Act Up. Move Forward." Disobedience-Based Arts Education

    ERIC Educational Resources Information Center

    Kotin, Alison; Aguirre McGregor, Stella; Pellecchia, DeAnna; Schatz, Ingrid; Liu, Shaw Pong

    2013-01-01

    In this essay, Alison Kotin, Stella Aguirre McGregor, DeAnna Pellecchia, Ingrid Schatz, and Shaw Pong Liu reflect on their experiences working with public high school students to create "Speak Out. Act Up. Move Forward.," a performative response to current and historical acts of civil disobedience. The authors--a group of instructors…

  16. Comparison Between Geometrically Focused Pulses Versus Filaments in Femtosecond Laser Ablation of Steel and Titanium Alloys (Reprint)

    DTIC Science & Technology

    2014-09-01

    Chen, H. Teng, Z. Wei, Z. Sheng, Phys. Rev. E 66, 016406 (2002) 7. W. Liu, f. Théberge, E. Arévalo, J.-F. Gravel, A. Becker, S.L. Chin , Opt. Lett. 30...31, 1139 (2006) 19. B. Zeng, T.-J. Wang, S. Hosseini, Y. Cheng, Z. Xu, W. Liu, S.L. Chin , J. Opt. Soc. Am. B 29, 3226 (2012) 20. D. R. Lide, editor...Bagchi, S.R. Krishnan, C.L. Arnold, G.R. Kumar, A. Couairon, Phys. Rev. A 82, 013805 (2010) 27. W. Liu, S.L. Chin , Opt. Express 13, 5750 (2005) 28. A.A

  17. JPRS Report, Arms Control

    DTIC Science & Technology

    2007-11-02

    members of the Army Intelligence Command led by Yi (? Chin -paek), and by the incident involving Min Pyong-ton, superintendent of the Military Academy...No Tae-u’s military reshuffles have been greatly challenged by rightist military forces, such as Kim Chin -yong. Thus, he conducted a resolute and...Defense Security Command Cho Nam- pung, Army Commanders Sin Mal-op and Yi Chin -sam, and Vice Chief of Staff of the Army Yi Mun-sok at the last stage of

  18. Integral inversion to Fraunhofer diffraction for particle sizing.

    PubMed

    Cao, Zhang; Xu, Lijun; Ding, Jie

    2009-09-01

    A new solution to the inversion of Fraunhofer diffraction for particle sizing was introduced. Compared with the well-known Chin-Shifrin inversion, it is an inversion of the form of integral transform and less sensitive to noise. Simulation results with noise-contaminated data were obtained and showed that the new inversion is better than the Chin-Shifrin inversion. Especially when the particle diameter was small, the new inversion still performed well, whereas the Chin-Shifrin inversion did not converge.

  19. Bitter Melon

    MedlinePlus

    African Cucumber, Ampalaya, Balsam Pear, Balsam-Apple, Balsambirne, Balsamo, Bitter Apple, Bitter Cucumber, Bitter Gourd, Bittergurke, Carilla Fruit, Carilla Gourd, Cerasee, Chinli-Chih, Cundeamor, Fructus Mormordicae Grosvenori, Karavella, Kathilla, ...

  20. Pulmonary hypertension - at home

    MedlinePlus

    Pulmonary hypertension (PAH) is abnormally high blood pressure in the arteries of the lungs. With PAH, the right side ... Chin K, Channick RN. Pulmonary hypertension. In: Broaddus VC, Mason ... Textbook of Respiratory Medicine . 6th ed. Philadelphia, PA: ...

  1. 27 CFR 479.85 - Identification of transferee.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ..., FIREARMS, AND EXPLOSIVES, DEPARTMENT OF JUSTICE FIREARMS AND AMMUNITION MACHINE GUNS, DESTRUCTIVE DEVICES... bare, with the distance from the top of the head to the point of the chin approximately 11/4...

  2. 27 CFR 479.63 - Identification of applicant.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ..., FIREARMS, AND EXPLOSIVES, DEPARTMENT OF JUSTICE FIREARMS AND AMMUNITION MACHINE GUNS, DESTRUCTIVE DEVICES... the distance from the top of the head to the point of the chin approximately 11/4 inches, and...

  3. 27 CFR 479.34 - Special tax registration and return.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ..., FIREARMS, AND EXPLOSIVES, DEPARTMENT OF JUSTICE FIREARMS AND AMMUNITION MACHINE GUNS, DESTRUCTIVE DEVICES... chin approximately 11/4 inches, and which shall have been taken within 6 months prior to the date...

  4. Genetics Home Reference: congenital generalized lipodystrophy

    MedlinePlus

    ... a large chin, prominent bones above the eyes ( orbital ridges ), large hands and feet, and a prominent ... E, Assan R, Baudic N, Bourut C, Czernichow P, Huet F, Grigorescu F, de Kerdanet M, Lacombe ...

  5. 29 CFR Appendix A to Subpart I of... - Non-Mandatory Guidelines for Hazard Assessment, Personal Protective Equipment (PPE) Selection...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... officer should observe: (1) Sources of motion; for example, machinery or processes where any movement of... to keep the hard hat on an employee's head. (Chin straps should break at a reasonably low force...

  6. 1. Historic American Buildings Survey E. W. Russell, Photographer, September ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Historic American Buildings Survey E. W. Russell, Photographer, September 15, 1936 GATE IN FRONT OF 201 GOVERNMENT STREET - 201 Government Street (Iron Gate), Moved to Spring Hill Avenue & Riviere du Chin Road, Mobile, Mobile County, AL

  7. Frostbite

    MedlinePlus

    ... cheeks and chin. Exposed skin in cold, windy weather is most vulnerable to frostbite. But frostbite can ... common cause of frostbite is exposure to cold-weather conditions. But it can also be caused by ...

  8. 75 FR 9028 - Quarterly Publication of Individuals, Who Have Chosen To Expatriate, as Required by Section 6039G

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-26

    ... KAREN-HELENA SABRINA HASSAN ABDELMONEM HAYDAY ADRIAN C ] HAYDAY SANDRA ANN HELBIG INGO M. HELD BETTINA... PAHLSSON REX HENRIK PAHR-IVERSEN KAREN-HELENA SABRINA HART PAK CHIN YONG PAK SUN YUL PAK YONG MAE PARK...

  9. Tonometry

    MedlinePlus

    ... records eye pressure. The last method is the noncontact method (air puff). In this method, your chin ... you should not have any pain. In the noncontact method, you may feel mild pressure on your ...

  10. Rosacea (image)

    MedlinePlus

    Rosacea is a condition where the area of the cheeks, nose, chin, forehead, or eyelids become inflamed. ... vessels, swelling, or skin eruptions similar to acne. Rosacea occurs most often in fair skinned people, particularly ...

  11. Congenital Heart Information Network

    MedlinePlus

    ... Baemayr for The Congenital Heart Information Network Exempt organization under Section 501(c)3. Copyright ©1996 - 2016 C.H.I.N. All rights reserved TX4-390-685 Original site design and HTML by Panoptic Communications

  12. Assessing the Effect of Honeypots on Cyber-Attackers

    DTIC Science & Technology

    2006-12-01

    will like to thank Yu Loon , Ng, and Chin Chin, Ng for their timely morale boosting discussion and support. Lastly, I will like extend my appreciation...honeypots. They were from organizations like Google , Microsoft Corporation, and Redshift (that hosted our DNS server). Further packet inspections...Protocol Size Organization Name Location 66.102.7.99 TCP 60 GOOGLE USA 216.228.2.120 DNS 239 REDSHIFT USA 216.228.2.120 DNS 334 REDSHIFT USA

  13. Mandible prognathism saved a life: a case report.

    PubMed

    Mahmood Hashemi, Hamid; Asgarian, Asadollah

    2010-10-01

    An unusual case of a suicidal firearm injury is presented, in which the victim placed the gun under his chin and fired. However, none of the vital structures of the head and face were injured because the victim's chin was considerably anterior to other facial structures as a result of a class III facial deformity. This resulted in the trajectory of the bullet being anterior to vital facial structures and not causing injury to those structures.

  14. History of Special Operations Forces in Malaysia

    DTIC Science & Technology

    2013-06-01

    step up the hunt in towns, red flags go up overnight,” The Straits Times, May 21, 1968. 204 Chin, Peng, Ian Ward, and Norma O. Miraflor, My Side of...There were many operations accomplished by the MSSU before the Second Emergency. Among them was Operation Apas Balong, in April 1966, near Slim Pompon...Westport, CT: Praeger, 1996. Chin, Peng, Ian Ward, and Norma O. Miraflor. My Side of History, Singapore: Media Masters, 2003. Chynowyth, John

  15. Remarks on a model for outbursts in luminous blue variables

    NASA Astrophysics Data System (ADS)

    Glatzel, W.; Kiriakidis, M.

    1998-03-01

    The stability of massive stars is re-examined with respect to an adiabatic dynamical instability discovered by Stothers & Chin. An adiabatic stability analysis is performed, its validity for the objects being considered is discussed, and the relation between the mean adiabatic index and adiabatic stability is commented on. As the results of Stothers & Chin could not be confirmed, we suspect that luminous blue variable instability is due to nonadiabatic effects.

  16. A Novel Anti-Beta2-Microglobulin Antibody Inhibition of Androgen Receptor Expression, Survival, and Progression in Prostate Cancer Cells

    DTIC Science & Technology

    2009-05-31

    expression and survival through a lipogenic pathway in prostate cancer Wen-Chin Huang, Guodong Zhu , Haiyen E. Zhau and Leland W. K. Chung Emory...Clinical Cancer Research Online (http://clincancerres.aacrjournals.org/). Requests for reprints: Wen-Chin Huang or Leland W.K. Chung , Molecular Urology...Konaka H, Sodek J, Zhau HE, Chung LW. Human Osteocalcin and Bone Sialoprotein Mediating Osteomimicry of Prostate Cancer Cells: Role of cAMP

  17. Interfacial and Thin Film Chemistry in Electron Device Fabrication

    DTIC Science & Technology

    1990-11-20

    264 (1990). M. T. Schmidt, Q. Y. Ma, L. S. Weinman, X. Wu, E. S. Yang, and Chin-An Chang, " Chesmistry and Resistance at Metal Contacts to YBa2Cu3O 7...Schmidt, Q. Y. Ma, L. S. Weinman, X. Wu, E. S. Yang, and Chin-An Chang, " Chesmistry and Resistance at Metal Contacts to YBa2Cu307 High Tc

  18. Noncoding RNA. piRNA-guided transposon cleavage initiates Zucchini-dependent, phased piRNA production.

    PubMed

    Han, Bo W; Wang, Wei; Li, Chengjian; Weng, Zhiping; Zamore, Phillip D

    2015-05-15

    PIWI-interacting RNAs (piRNAs) protect the animal germ line by silencing transposons. Primary piRNAs, generated from transcripts of genomic transposon "junkyards" (piRNA clusters), are amplified by the "ping-pong" pathway, yielding secondary piRNAs. We report that secondary piRNAs, bound to the PIWI protein Ago3, can initiate primary piRNA production from cleaved transposon RNAs. The first ~26 nucleotides (nt) of each cleaved RNA becomes a secondary piRNA, but the subsequent ~26 nt become the first in a series of phased primary piRNAs that bind Piwi, allowing piRNAs to spread beyond the site of RNA cleavage. The ping-pong pathway increases only the abundance of piRNAs, whereas production of phased primary piRNAs from cleaved transposon RNAs adds sequence diversity to the piRNA pool, allowing adaptation to changes in transposon sequence.

  19. Multiagent cooperation and competition with deep reinforcement learning.

    PubMed

    Tampuu, Ardi; Matiisen, Tambet; Kodelja, Dorian; Kuzovkin, Ilya; Korjus, Kristjan; Aru, Juhan; Aru, Jaan; Vicente, Raul

    2017-01-01

    Evolution of cooperation and competition can appear when multiple adaptive agents share a biological, social, or technological niche. In the present work we study how cooperation and competition emerge between autonomous agents that learn by reinforcement while using only their raw visual input as the state representation. In particular, we extend the Deep Q-Learning framework to multiagent environments to investigate the interaction between two learning agents in the well-known video game Pong. By manipulating the classical rewarding scheme of Pong we show how competitive and collaborative behaviors emerge. We also describe the progression from competitive to collaborative behavior when the incentive to cooperate is increased. Finally we show how learning by playing against another adaptive agent, instead of against a hard-wired algorithm, results in more robust strategies. The present work shows that Deep Q-Networks can become a useful tool for studying decentralized learning of multiagent systems coping with high-dimensional environments.

  20. MVH in piRNA processing and gene silencing of retrotransposons.

    PubMed

    Kuramochi-Miyagawa, Satomi; Watanabe, Toshiaki; Gotoh, Kengo; Takamatsu, Kana; Chuma, Shinichiro; Kojima-Kita, Kanako; Shiromoto, Yusuke; Asada, Noriko; Toyoda, Atsushi; Fujiyama, Asao; Totoki, Yasushi; Shibata, Tatsuhiro; Kimura, Tohru; Nakatsuji, Norio; Noce, Toshiaki; Sasaki, Hiroyuki; Nakano, Toru

    2010-05-01

    VASA is an evolutionarily conserved RNA helicase essential for germ cell development. The mouse PIWI family proteins MILI and MIWI2 are involved in production of Piwi-interacting RNAs (piRNAs) in fetal male germ cells through a ping-pong amplification cycle. Expression of retrotransposons is elevated in MILI- and MIWI2-deficient male germ cells due to defective de novo DNA methylation, which is presumably caused by impaired piRNA expression. Here, we report that essentially the same abnormalities are observed in MVH (mouse VASA homolog)-deficient mice. Comprehensive analysis of piRNAs in MVH-deficient fetal male germ cells showed that MVH plays crucial roles in the early phase of the ping-pong amplification cycle.

  1. The Design and Evaluation of a High Performance Smalltalk System

    DTIC Science & Technology

    1986-02-01

    detailed in Pendleton’s doctoral dissetaon [Pong~bi. A summary of this chapter has been previously published [UDFS4]. A more detailed architec- tural... tesi sOrganaizer instructions 41.06% 58.94% 100% cycles 42.56% 57.44% 100% avg. rgs containing pointers per rtw n.a. 1.60 n.a. avg emp van 0-1 na. La

  2. Spin-Orbit Interaction of a Photon in AN Inhomogeneous Medium

    NASA Astrophysics Data System (ADS)

    Liberman, V. S.; Zel'Dovich, B. Ya.

    The following sections are included: * Introduction * Transverse Shift of the Circularly Polarized Beam (CPB) due to Refraction * Differential Equations for a Trajectory and Polarization of the Ray. Hamilton's Form of the Equations * Optical Magnus Effect in a Graded-Index Waveguide * Optical Ping-Pong Effect in a Step-Like Index Waveguide * Paraxial Approximation for Maxwell's Equations * Spin-Orbit Corrections to the Paraxial Approximation: Hermitian Interaction Hamiltonian * The Wave Description of the Optical Magnus Effect * Conclusion * Acknowledgement * References

  3. The Built Environment of Cold War Era Servicewomen

    DTIC Science & Technology

    2006-08-01

    sculpture, music, dramatics, folk and ballroom dancing , photography and group singing” (Figure 70 and Figure 71).159 Also, female restrooms and “powder...Enlisted Survey of 1964-65).....................................................................95 ERDC/CERL M-06-2 viii Figure 70. Dance at WAC...soda fountain, library, and ping-pong and dance room.”31 29 Commandant, U.S. Marine

  4. Correctness and completeness of the theory of bio-energy transport. Reply to the comments on “The theory of bio-energy transport in the protein molecules and its properties”

    NASA Astrophysics Data System (ADS)

    Pang, Xiao Feng

    2011-10-01

    Commentaries by Philip W.T. Pong, Nongyue He, S.D. Liang, Tao Song, Yuri Gaididei and Sergey Volkov and Alexander Y. Grosberg on my review article (Pang, 2011 [1]) are answered. The validity of Davydov's mechanism of bio-energy transport, the completeness of theory, outstanding problems, the normalization and validity of wave function of the system in Pang' model as well as other related problems are elucidated in detail.

  5. Single-Photon Secure Quantum Dialogue Protocol Without Information Leakage

    NASA Astrophysics Data System (ADS)

    Zhou, Nan-Run; Hua, Tian-Xiang; Wu, Gui-Tong; He, Chao-Sheng; Zhang, Ye

    2014-11-01

    Combining the idea of ping-pong protocol with Controlled-NOT operation, we propose a secure quantum dialogue protocol based on single-photonss. Bob obtains the information of the encrypted quantum state by performing Controlled-NOT operation on the auxiliary particle and the encrypted single-photonss. Unlike the previous quantum dialogue protocols based on single-photonss, the proposed protocol not only overcomes information leakage but also possesses an acceptable efficiency.

  6. The ball SITE sign: Ball sports-induced targetoid erythema in a racquetball player

    PubMed Central

    Cohen, Philip R.

    2015-01-01

    Background: Cutaneous injury following impact of a high velocity ball to the skin may result in either erythema or purpura or both. The lesion typically appears as an annular ring of erythema with or without accompanying ecchymosis when the skin is contacted by a paintball, a ping pong ball, a racquetball or a squash ball. Purpose: To describe a girl with targetoid erythema following impact of a racquetball on her flank and back and to review other sports associated with this response to skin injury. Methods: PubMed was used to search the following terms, separately and in combination: ball, erythema, paint, ping pong, purpura, racquetball, sign, site, sports, squash, targetoid. All papers were reviewed and relevant manuscripts, along with their reference citations, were evaluated. Results: A 13-year-old girl developed an annular red ring surrounding a central area of normal appearing skin on her right flank and upper back where a racquetball traveling at a high velocity contacted her skin. Similar appearing lesions of targetoid erythema have been described at the cutaneous impact sites of either paintballs, ping pong balls, squash balls; in addition to erythema, purpura may also concurrently appear or subsequently develop at the contact location of the ball with the skin. Conclusions: Targetoid erythema is a pathognomonic cutaneous presentation resulting from the impact of either a paintball, ping pong ball, racquetball or squash ball—that is traveling at a high velocity—with a sport participant’s skin. The ball SITE (sports-induced targetoid erythema) sign is suggested as a unifying nomenclature to designate this unique, ball sport-associated, cutaneous dermatosis in athletes participating in sports in which high velocity impact of the ball with the skin may occur. PMID:26336625

  7. The China Factor in America’s Foreign Relations: Perceptions and Policy Choices,

    DTIC Science & Technology

    1981-05-01

    cooperation, also had a powerful impact on worldwide perceptions of international relations: the "Nixon shock" effect on the Japanese ; the consternation of...terraced fields, and an exotic cuisine . There are, as well, dark images of China derived from the country’s millennial poverty, periods of political...pong diplomacy," the artistic wonders of China’s imperial past, and opportunities for trade and tourism with a talented and hard-working people

  8. Improvements in Routing for Packet-Switched Networks

    DTIC Science & Technology

    1975-02-18

    the routing table at X is then updated by a simple averaging process. 2.3.6 Negative Reinfafccrnent Negative reinforcement is a class of techniques...is to reduce the "ping-pong" effect. 2.3.7 Bi-adaptive Bi-adaptivc is still a further synthesis of backwards learning and negative reinforcement , where...table en- tries can only be increased by negative reinforcement and decreased by backward learning. 2 .-.8 Superposition Superposition is

  9. Development of an Experimental Test for Evaluating Understanding of Spoken English

    DTIC Science & Technology

    1952-11-01

    lea cuidado samnte las cuatro oragiones quo aparecen equl. Pong uns "X" an el cu1dro al ado do la oracion quo Ud. Crea ser la ~traduccon m~a ccreocta...do la oracion en Ingle’s quo Md. 030. i 1. 1 live in Sari Juan. (5 ecoids) Ud. debio haber puesto una en el cuadro correcto. Si no lo ha hecho hagalo

  10. Final design proposal: Delta Group-Nood Rider 821(tm)

    NASA Technical Reports Server (NTRS)

    Pastega, C. B.; Vahey, B. P.; Hoffman, K. W.; Doherty, M. C.; Fay, M. J.; Konesky, A. L.; Lilly, D. C.; Moody, D. J.

    1991-01-01

    The Nood Rider 821 (trademark) twin-engine, prop passenger aircraft is described. It is argued that the aircraft is very economical to operate and maintain, offering competitive advantages in the air travel marketplace. The aircraft was designed to operate in 'Aeroworld', a fictional world where the passengers are ping pong balls and the distances between cites are on the order of thousands of feet.

  11. Full-color 3D display using binary phase modulation and speckle reduction

    NASA Astrophysics Data System (ADS)

    Matoba, Osamu; Masuda, Kazunobu; Harada, Syo; Nitta, Kouichi

    2016-06-01

    One of the 3D display systems for full-color reconstruction by using binary phase modulation is presented. The improvement of reconstructed objects is achieved by optimizing the binary phase modulation and accumulating the speckle patterns by changing the random phase distributions. The binary phase pattern is optimized by the modified Frenel ping-pong algorithm. Numerical and experimental demonstrations of full color reconstruction are presented.

  12. RNF17 blocks promiscuous activity of PIWI proteins in mouse testes

    PubMed Central

    Wasik, Kaja A.; Tam, Oliver H.; Knott, Simon R.; Falciatori, Ilaria; Hammell, Molly; Vagin, Vasily V.; Hannon, Gregory J.

    2015-01-01

    PIWI proteins and their associated piRNAs protect germ cells from the activity of mobile genetic elements. Two classes of piRNAs—primary and secondary—are defined by their mechanisms of biogenesis. Primary piRNAs are processed directly from transcripts of piRNA cluster loci, whereas secondary piRNAs are generated in an adaptive amplification loop, termed the ping-pong cycle. In mammals, piRNA populations are dynamic, shifting as male germ cells develop. Embryonic piRNAs consist of both primary and secondary species and are mainly directed toward transposons. In meiotic cells, the piRNA population is transposon-poor and largely restricted to primary piRNAs derived from pachytene piRNA clusters. The transition from the embryonic to the adult piRNA pathway is not well understood. Here we show that RNF17 shapes adult meiotic piRNA content by suppressing the production of secondary piRNAs. In the absence of RNF17, ping-pong occurs inappropriately in meiotic cells. Ping-pong initiates piRNA responses against not only transposons but also protein-coding genes and long noncoding RNAs, including genes essential for germ cell development. Thus, the sterility of Rnf17 mutants may be a manifestation of a small RNA-based autoimmune reaction. PMID:26115953

  13. The Drosophila HP1 homologue Rhino is required for transposon silencing and piRNA production by dual strand clusters

    PubMed Central

    Klattenhoff, Carla; Xi, Hualin; Li, Chengjian; Lee, Soohyun; Xu, Jia; Khurana, Jaspreet S.; Zhang, Fan; Schultz, Nadine; Koppetsch, Birgit S.; Nowosielska, Anetta; Seitz, Herve; Zamore, Phillip D.; Weng, Zhiping; Theurkauf, William E.

    2009-01-01

    Summary piRNAs silence transposons and maintain genome integrity during germ-line development. In Drosophila, transposon-rich heterochromatic clusters encode piRNAs either on both genomic strands (dual-strand clusters) or predominantly one genomic strand (uni-strand clusters). Primary piRNAs derived from these clusters are proposed to drive a ping-pong amplification cycle catalyzed by proteins that localize to the perinuclear nuage. We show that the HP1 homologue Rhino is required for nuage organization, transposon silencing, and ping-pong amplification of piRNAs. rhi mutations virtually eliminate piRNAs from the dual-strand clusters and block production of putative precursor RNAs from both strands of the major 42AB dual-strand cluster, but do not block production of transcripts or piRNAs from the uni-strand clusters. Furthermore, Rhino protein associates with the 42AB dual-strand cluster, but does not bind to uni-strand cluster 2 or flamenco. Rhino thus appears to promote transcription of dual-strand clusters, leading to production of piRNAs that drive the ping-pong amplification cycle. PMID:19732946

  14. The Rolling Release Rulapult

    NASA Astrophysics Data System (ADS)

    West, Joseph; Ross, Seth; Flesher, James

    2011-09-01

    The "rulapult" is a low-cost, easy-to-construct, ruler-based catapult for use in the classroom. It is made from durable, inexpensive items that are easy to store. Most of the components can be found with a visit to one or two local stores. A set of 12 complete rulapults can be constructed for less than 150, including the one-time cost of the only tool needed for construction, a single handheld one-hole paper punch. The unit price per rulapult approaches 10.25 as the number of rulapults constructed becomes "large." A rulapult can be constructed by a single middle school student in less than five minutes. Ping-Pong® balls or marshmallows are suggested for use as projectiles as they pose a minimal safety hazard. The range of a typical rulapult when firing a Ping-Pong ball is approximately 4.0 m, just right for classroom or hallway testing. The smaller (1-cm size) marshmallows have a range of about 5.0 m, but due to their "squishy" nature, the range is less consistent from shot to shot. For the rest of the discussion, it is presumed that the projectile is a Ping-Pong ball (the ball). The ball can easily knock over a large Styrofoam™ cup, but despite its impressive range and "knock-down power," the rulers used are "limp" enough that a direct hit to your hand by the ruler will not cause noticeable pain or injury.

  15. Scent marking, dominance and serum testosterone levels in male domestic rabbits.

    PubMed

    Arteaga, Lourdes; Bautista, Amando; Martínez-Gómez, Margarita; Nicolás, Leticia; Hudson, Robyn

    2008-06-09

    The European rabbit, both in its wild and domesticated forms, has been a pioneer species in the study of mammalian chemical communication, and illustrates well the difficulty of understanding the functional significance of these often complex signals. Here we investigate the performance of one of the rabbit's most conspicuous chemical signaling behaviors, chin marking (chinning), and the hypothesis that this expresses social dominance. In tests of 21 chinchilla-strain sexually mature males we predicted 1) that animals would show marked and stable individual differences in the frequency of chinning, 2) that these differences would correlate with behaviors associated with dominance such as intrasexual mounting, and 3) that individual differences in the frequency of chinning and dominance-related behaviors would correlate with individual differences in a commonly used physiological indicator of dominance, concentration of serum testosterone. Supporting these predictions and consistent with previous reports, animals showed large and stable individual differences in the frequency of chinning which correlated with the behavioral indicators of dominance and less strongly, with serum testosterone. As our animals had been kept in single cages and without direct contact with other males since weaning, these findings raise the question as to how and when during development such differences among individuals arise. We are currently investigating the possible relation between pups' intrauterine position, postnatal competition among littermates for milk and thermally advantageous positions in the litter huddle, and later differences in indicators of dominance such as those reported here.

  16. [Removal of the sagging of the tissues in the submental area].

    PubMed

    Ezrokhin, V M

    1995-01-01

    Twenty out of 100 patients operated on to remove skin excess on the face and neck had slackening tissue under the chin. Based on published data and their findings, the authors developed operations to remove slackening tissue under the chin and carried out such operations in 64 patients. Isolated lipectomy failed to bring about good results in cases when there were indications for removal of skin excess on the face neck (10 patients). Simultaneous removal of skin excess on the face and lipectomy helped attain good results in 50 patients. The operation is possible in patients with a low position of the sublingual bone, although the results are not so good. Lipectomy in the area under the chin is recommended as a method supplementing operation for removal of skin excess on the face and neck.

  17. Common Errors in Digital Panoramic Radiographs of Patients with Mixed Dentition and Patients with Permanent Dentition

    PubMed Central

    Peretz, Benjamin; Gotler, Maya; Kaffe, Israel

    2012-01-01

    Purpose. To compare errors in digital panoramic radiographs of permanent and mixed dentitions. Methods. 143 and 146 digital radiographs of mixed and permanent dentitions were examined. Results. Significantly fewer errors presented in the mixed dentition. Positioning too forward significantly prevalent in the mixed dentition; slumped position and nonpositioning of chin properly were significantly prevailed in the permanent dentition. Blurred or shortened upper incisors were significantly more prevalent in the mixed dentition. Diagnostic ability could be improved by manipulating the brightness or contrast in nearly 45% of all radiographs. In the mixed dentition, tilting the chin down and a slumped position made the lower incisors significantly nondiagnostic. In the permanent dentition, tilting the chin down made the lower incisors to be significantly nondiagnostic. Conclusions. More errors were prevalent in panoramic radiographs of permanent dentitions. Properly positioning the patient is the most important factor in preventing a cascade of errors. PMID:22505905

  18. Study of Aerosol/Cloud/Radiation Interactions over the ARM SGP Site

    SciTech Connect

    Chuang, C; Chin, S

    2006-03-14

    While considerable advances in the understanding of atmospheric processes and feedbacks in the climate system have led to a better representation of these mechanisms in general circulation models (GCMs), the greatest uncertainty in predictability of future climate arises from clouds and their interactions with radiation. To explore this uncertainty, cloud resolving model has been evolved as one of the main tools for understanding and testing cloud feedback processes in climate models, whereas the indirect effects of aerosols are closely linked with cloud feedback processes. In this study we incorporated an existing parameterization of cloud drop concentration (Chuang et al., 2002a) together with aerosol prediction from a global chemistry/aerosol model (IMPACT) (Rotman et al., 2004; Chuang et al., 2002b; Chuang et al., 2005) into LLNL cloud resolving model (Chin, 1994; Chin et al., 1995; Chin and Wilhelmson, 1998) to investigate the effects of aerosols on cloud/precipitation properties and the resulting radiation fields over the Southern Great Plains.

  19. Bone remodeling to correct maxillary deficiency after growth cessation

    PubMed Central

    Showkatbakhsh, Rahman; Ghassemi, Alireza; Gerressen, Marcus; Ghassemi, Mehrangiz; Jamilian, Abdolreza; Mohammad, Shadab; Pal, Uma S.

    2012-01-01

    This case report presents a 22-year-old girl with class III malocclusion due to maxillary deficiency. The patient was referred for presurgical orthodontics; however, she rejected the surgery. This case was treated by means of Tongue appliance and slow palatal expansion, followed by lower fixed appliance, reverse chin cup, and upper fixed appliance. Tongue appliance and slow palatal expansion were used at the beginning of the treatment. After 6 months, reverse chin cup and lower fixed appliance were added. Six months later reverse chin cup was removed and upper fixed appliance was mounted. Positive overbite and over jet were achieved after 24 months of active treatment. Nasolabial angle also showed improvement. Nonsurgical treatment of adult class III patients is a difficult procedure; however, this patient was treated nonsurgically. PMID:23833499

  20. Cone-Beam Computed Tomography Assessment of Lower Facial Asymmetry in Unilateral Cleft Lip and Palate and Non-Cleft Patients with Class III Skeletal Relationship

    PubMed Central

    Lin, Yifan; Chen, Gui; Fu, Zhen; Ma, Lian; Li, Weiran

    2015-01-01

    Introduction To evaluate, using cone-beam computed tomography (CBCT), both the condylar-fossa relationships and the mandibular and condylar asymmetries between unilateral cleft lip and palate (UCLP) patients and non-cleft patients with class III skeletal relationship, and to investigate the factors of asymmetry contributing to chin deviation. Methods The UCLP and non-cleft groups consisted of 30 and 40 subjects, respectively, in mixed dentition with class III skeletal relationships. Condylar-fossa relationships and the dimensional and positional asymmetries of the condyles and mandibles were examined using CBCT. Intra-group differences were compared between two sides in both groups using a paired t-test. Furthermore, correlations between each measurement and chin deviation were assessed. Results It was observed that 90% of UCLP and 67.5% of non-cleft subjects had both condyles centered, and no significant asymmetry was found. The axial angle and the condylar center distances to the midsagittal plane were significantly greater on the cleft side than on the non-cleft side (P=0.001 and P=0.028, respectively) and were positively correlated with chin deviation in the UCLP group. Except for a larger gonial angle on the cleft side, the two groups presented with consistent asymmetries showing shorter mandibular bodies and total mandibular lengths on the cleft (deviated) side. The average chin deviation was 1.63 mm to the cleft side, and the average absolute chin deviation was significantly greater in the UCLP group than in the non-cleft group (P=0.037). Conclusion Compared with non-cleft subjects with similar class III skeletal relationships, the subjects with UCLP showed more severe lower facial asymmetry. The subjects with UCLP presented with more asymmetrical positions and rotations of the condyles on axial slices, which were positively correlated with chin deviation. PMID:26237311

  1. Efficient quantum secret sharing scheme with two-particle entangled states

    NASA Astrophysics Data System (ADS)

    Zhu, Zhen-Chao; Zhang, Yu-Qing; Fu, An-Min

    2011-04-01

    This paper proposes a protocol for multi-party quantum secret sharing utilizing four non-orthogonal two-particle entangled states following some ideas in the schemes proposed by Liu et al. (2006 Chin. Phys. Lett. 23 3148) and Zhang et al. (2009 Chin. Phys. B 18 2149) respectively. The theoretical efficiency for qubits of the new protocol is improved from 50% to approaching 100%. All the entangled states can be used for generating the private key except those used for the eavesdropping check. The validity of a probable attack called opaque cheat attack to this kind of protocols is considered in the paper for the first time.

  2. Uncovering the CH-53E Doppler Myth

    DTIC Science & Technology

    2008-01-01

    shift, of the transmitted energy as it returns to the receiver. Similar to the "radar guns " used by police officers to 9 r Figure 3. TRNS, PSN, HVR HNVS...aircraft is in an unwanted roll that can manifest in to dangerous lateral drifting. A visual scan through the lower " chin bubble" allows the pilots to...instrument and gages coupled with the copilot’s and aircrew’s verbal "calls" completes the teamwork needed to maneuver and land the aircraft safely. Chin

  3. Prolene mesh mentoplasty.

    PubMed

    Ilhan, A Emre; Kayabasoglu, Gurkan; Kazikdas, K Cagdas; Goksel, Abdulkadir

    2011-04-01

    Augmentation mentoplasty is a cosmetic surgical procedure to correct chin retrusion or microgenia which usually requires placement of an alloplastic material over the pogonion, and which results in increased chin projection and a more aesthetically balanced facial profile. Polypropylene mesh is easy to purchase, widely available in a general hospital and most commonly used by general surgeons. In this series of 192 patients, we wanted to demonstrate our simple mentoplasty technique using prolene mesh that can easily be combined with a rhinoplasty procedure, with possible causes of infection and the rationale for using prolene mesh in such procedures.

  4. Experimental Data in Support of a Direct Displacement Mechanism for Type I/II L-Asparaginases.

    PubMed

    Schalk, Amanda M; Antansijevic, Aleksandar; Caffrey, Michael; Lavie, Arnon

    2016-03-04

    Bacterial L-asparaginases play an important role in the treatment of certain types of blood cancers. We are exploring the guinea pig L-asparaginase (gpASNase1) as a potential replacement of the immunogenic bacterial enzymes. The exact mechanism used by L-asparaginases to catalyze the hydrolysis of asparagine into aspartic acid and ammonia has been recently put into question. Earlier experimental data suggested that the reaction proceeds via a covalent intermediate using a ping-pong mechanism, whereas recent computational work advocates the direct displacement of the amine by an activated water. To shed light on this controversy, we generated gpASNase1 mutants of conserved active site residues (T19A, T116A, T19A/T116A, K188M, and Y308F) suspected to play a role in hydrolysis. Using x-ray crystallography, we determined the crystal structures of the T19A, T116A, and K188M mutants soaked in asparagine. We also characterized their steady-state kinetic properties and analyzed the conversion of asparagine to aspartate using NMR. Our structures reveal bound asparagine in the active site that has unambiguously not formed a covalent intermediate. Kinetic and NMR assays detect significant residual activity for all of the mutants. Furthermore, no burst of ammonia production was observed that would indicate covalent intermediate formation and the presence of a ping-pong mechanism. Hence, despite using a variety of techniques, we were unable to obtain experimental evidence that would support the formation of a covalent intermediate. Consequently, our observations support a direct displacement rather than a ping-pong mechanism for l-asparaginases.

  5. Experimental Data in Support of a Direct Displacement Mechanism for Type I/II l-Asparaginases*

    PubMed Central

    Schalk, Amanda M.; Antansijevic, Aleksandar; Caffrey, Michael; Lavie, Arnon

    2016-01-01

    Bacterial l-asparaginases play an important role in the treatment of certain types of blood cancers. We are exploring the guinea pig l-asparaginase (gpASNase1) as a potential replacement of the immunogenic bacterial enzymes. The exact mechanism used by l-asparaginases to catalyze the hydrolysis of asparagine into aspartic acid and ammonia has been recently put into question. Earlier experimental data suggested that the reaction proceeds via a covalent intermediate using a ping-pong mechanism, whereas recent computational work advocates the direct displacement of the amine by an activated water. To shed light on this controversy, we generated gpASNase1 mutants of conserved active site residues (T19A, T116A, T19A/T116A, K188M, and Y308F) suspected to play a role in hydrolysis. Using x-ray crystallography, we determined the crystal structures of the T19A, T116A, and K188M mutants soaked in asparagine. We also characterized their steady-state kinetic properties and analyzed the conversion of asparagine to aspartate using NMR. Our structures reveal bound asparagine in the active site that has unambiguously not formed a covalent intermediate. Kinetic and NMR assays detect significant residual activity for all of the mutants. Furthermore, no burst of ammonia production was observed that would indicate covalent intermediate formation and the presence of a ping-pong mechanism. Hence, despite using a variety of techniques, we were unable to obtain experimental evidence that would support the formation of a covalent intermediate. Consequently, our observations support a direct displacement rather than a ping-pong mechanism for l-asparaginases. PMID:26733195

  6. Effect of chain length of alcohol on the lipase-catalyzed esterification of propionic acid in supercritical carbon dioxide.

    PubMed

    Varma, Mahesh N; Madras, Giridhar

    2010-04-01

    The esterification of propionic acid was investigated using three different alcohols, namely, isopropyl alcohol, isobutyl alcohol, and isoamyl alcohol. The variation of conversion with time for the synthesis of isoamyl propionate was investigated in the presence of five enzymes. Novozym 435 showed the highest activity, and this was used as the enzyme for investigating the various parameters that influence the esterification reaction. The Ping-Pong Bi-Bi model with inhibition by both acid and alcohol was used to model the experimental data and determine the kinetics of the esterification reaction.

  7. A sporting chance to fight haze

    NASA Astrophysics Data System (ADS)

    Showstack, Randy

    Sometimes sports can open up the way for politicians to take action. Several decades ago, ping-pong diplomacy helped to ease tensions between China and the United States. Now, it appears that the upcoming Southeast Asia Games (SEA Games) also may be wielding some influence in policy making.Environment ministers from countries in the region and officials from the Association of South East Asian Nations (ASEAN), hoping to keep the skies clear during the sporting competition in Brunei in August, on July 6 announced a plan to try to prevent forest fires and avert the dangerous levels of smog and haze that enveloped the region 2 years ago.

  8. Proportional Increase Multiplicative Decrease (PIMD) Wireless Scheduler: An Efficient Scheduler for IEEE 802.11e HCF

    NASA Astrophysics Data System (ADS)

    Hussain, Arshad; Qaiser, Shaban

    In this paper, we propose a new wireless scheduling algorithm for the IEEE 802.11e HCF. The algorithm grants the mobile stations variable time for the upstream data flow in proportion to the queue size of the transmission buffer. At the same time, it retrieves half of the extra time allocated in previous cycle from those flows whose requirement has stopped. Hence, the system achieves stability by preventing the ping-pong phenomena. The algorithm is computationally simple, and as compared to the other algorithms, it gives bounded delays and jitter to the real-time applications under heavy load conditions.

  9. Intersystem Crossing Mechanisms and Single Molecule Fluorescence: Terrylene in Anthracene Crystals

    SciTech Connect

    Kol'chenko, M.A.; Nicolet, A.; Orrit, M.; Kozankiewicz, B.

    2005-05-15

    Single molecule spectroscopy requires molecules with low triplet yields and/or short triplet lifetimes. The intersystem crossing (ISC) rate may be dramatically enhanced by the host matrix. Comparing the fluorescence intensity of single terrylene molecules in para-terphenyl, naphthalene, and anthracene crystals, we found a reduction of the saturation intensity by three orders of magnitude in the latter case. The fluorescence autocorrelation function indicates that the bottleneck state is the terrylene triplet. We propose a ping-pong mechanism between host and guest. This intermolecular ISC mechanism, which can open whenever the host triplet lies lower than the guest singlet, was overlooked in previous single molecule investigations.

  10. W. W. "Mo" Cleland: a catalytic life.

    PubMed

    Dunaway-Mariano, Debra; Holden, Hazel M; Raushel, Frank M

    2013-12-23

    Professor W. Wallace Cleland, the architect of modern steady-state enzyme kinetics, died on March 6, 2013, from injuries sustained in a fall outside of his home. He will be most remembered for giving the enzyme community Ping-Pong kinetics and the invention of dithiothreitol (DTT). He pioneered the utilization of heavy atom isotope effects for the elucidation of the chemical mechanisms of enzyme-catalyzed reactions. His favorite research journal was Biochemistry, in which he published more than 135 papers beginning in 1964 with the disclosure of DTT.

  11. Success for ``Physics on Stage'' Festival in Geneva

    NASA Astrophysics Data System (ADS)

    Madsen, C.; West, R.

    2000-12-01

    Can you imagine how much physics is in a simple match of ping-pong, in throwing a boomerang, or in a musical concert? Physics is all around us and governs our lives. But who is going to maintain these technologies and develop new ones in the future? Recent surveys show a frightening decline of interest in physics and technology among E u r o p e 's citizens, especially school children. Fewer and fewer young people enrol in physics courses at Europe's universities while scepticism towards science and technology is spreading and causing great concern among governments and educators.

  12. Economic evaluation techniques for the environment

    SciTech Connect

    Dixon, J.A.; Hufschmidt, M.M.

    1986-01-01

    This book discusses the methods of evaluating seven case studies. Three chapters are introductory discussing a hypothetical case. The following seven chapters discuss respectively: Economic Evaluation of Tongonan Geothermal Power Plant Project in Leyte, Philippines; Evaluation of Losses of Marine Product Resources Caused by Coastal Development of Tokyo, Bay; Evaluation of Lumpinee Public Park in Bangkok, Thailand; The Pam Pong Water Resources Project in Thailand; Selected Policy Options for the Fuelwood Production and Use in the Philippines; and Systematic Analysis of Water Pollution Control Options in a Suburban Region of Beijing, China.

  13. Numerical study of two classes of cellular automaton models for traffic flow on a two-lane roadway

    NASA Astrophysics Data System (ADS)

    Moussa, N.; Daoudia, A. K.

    2003-02-01

    In this paper, we present computer simulation results of traffic flow on a two-lane roadway with different types of vehicles, cars and trucks for example. We consider two classes of two-lane traffic cellular automaton models, namely the well known Nagel-Schreckenberg model and an extension of the Fukui-Ishibashi model. These two models, which differ in their acceleration limits, show an important differences in their fundamental diagrams, lane-changing and ping-pong behaviors. Moreover, we investigate the importance of braking noise and the proportion of trucks on the traffic flow of a two-lane roadway.

  14. Adaptive strategy for multi-user robotic rehabilitation games.

    PubMed

    Caurin, Glauco A P; Siqueira, Adriano A G; Andrade, Kleber O; Joaquim, Ricardo C; Krebs, Hermano I

    2011-01-01

    In this paper, we discuss a strategy for the adaptation of the "difficulty level" in games intended to include motor planning during robotic rehabilitation. We consider concurrently the motivation of the user and his/her performance in a Pong game. User motivation is classified in three levels (not motivated, well motivated and overloaded). User performance is measured as a combination of knowledge of results--achieved goals and score points in the game--and knowledge of performance--joint displacement, speed, aiming, user work, etc. Initial results of a pilot test with unimpaired healthy young volunteers are also presented showing a tendency for individualization of the parameter values.

  15. Sub-Saharan Africa Report No. 2639.

    DTIC Science & Technology

    2007-11-02

    favour 0 f PONG. 12. h~cdetLCkhelanity And voy. C90s 4700/1281 23 M.L-PARTY COWERECE IS ANSW~ER, SAYS SAMU KinhO~k THE VIUDB)EK ADVERTISE in Zhgliah 19...34e living neat fromk poliia samue . $NMpeI te the Woee- -.to ad1". but a" ~gis k the mis "lm a nt buanocue i zw PreoIn~s ’.os -.ol m.teo Coomeds FOO6J

  16. Role of MicroRNA in Aggressive Prostate Cancer

    DTIC Science & Technology

    2013-07-01

    SUBTITLE Role of microRNA in aggressive prostate cancer 5a. CONTRACT NUMBER W81XWH-11-1-0491 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER... cancer lesion, we applied ISH on formalin-fixed paraffin embedded (FFPE) tissue . We first confirmed the specificity of miR363 probe using benign...with prostate cancer development. REPORTABLE OUTCOMES Lo, U., Pong, R.C., Tseng, S.F., Hsieh, J.T. (2013) MicroRNA -363 regulated by a novel

  17. Final design proposal: Beta Systems-El Toro. A proposal in response to a commercial air transportation study

    NASA Technical Reports Server (NTRS)

    Muenzberg, Steve; Gillespie, Shane; Coogan, Jim; Monahan, Pat; Bruen, Liam; Wincer, Bob; Wilkey, Rob

    1991-01-01

    El Toro is a remotely piloted airplane designed to operate as a commercial aircraft in a fictional 'Aeroworld' where the passengers are ping-pong balls and the distances between cities are on the order of thousands of feet. The present design for El Toro will profitably meet the requirements for operation in Aeroworld with a ticket price comparable the ticket prices of current transportation. The extended range of El Toro allows for numerous flights to be flown before the battery pack needs to be changed. This drastically reduces the operating costs to the airlines, allowing them to charge less for a ticket or else to realize a higher profit margin.

  18. Can longer forest harvest intervals increase summer streamflow for salmon recovery?

    EPA Science Inventory

    The Mashel Streamflow Modeling Project in the Mashel River Basin, Washington, is using a watershed-scale ecohydrological model to assess whether longer forest harvest intervals can remediate summer low flow conditions that have contributed to sharply reduced runs of spawning Chin...

  19. Revisiting the Authoritative-Dialogic Tension in Inquiry-Based Elementary Science Teacher Questioning

    ERIC Educational Resources Information Center

    Van Booven, Christopher D.

    2015-01-01

    Building on the "questioning-based discourse analytical" framework developed by Singapore-based science educator and discourse analyst, Christine Chin, this study investigated the extent to which fifth-grade science teachers' use of questions with either an authoritative or dialogic orientation differentially restricted or expanded the…

  20. 42 CFR 84.1130 - Respirators; description.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... respective vapors, or from the chemical reaction between their respective vapors and gases. (3) Air-purifying... reaction with sorbent material in the canister. (c) Pesticide respirators, including all completely...) Front-mounted or back-mounted gas masks; (2) Chin-style gas mask; (3) Chemical cartridge; (4)...

  1. 42 CFR 84.1130 - Respirators; description.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... respective vapors, or from the chemical reaction between their respective vapors and gases. (3) Air-purifying... reaction with sorbent material in the canister. (c) Pesticide respirators, including all completely...) Front-mounted or back-mounted gas masks; (2) Chin-style gas mask; (3) Chemical cartridge; (4)...

  2. 42 CFR 84.1130 - Respirators; description.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... respective vapors, or from the chemical reaction between their respective vapors and gases. (3) Air-purifying... reaction with sorbent material in the canister. (c) Pesticide respirators, including all completely...) Front-mounted or back-mounted gas masks; (2) Chin-style gas mask; (3) Chemical cartridge; (4)...

  3. 42 CFR 84.1130 - Respirators; description.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... respective vapors, or from the chemical reaction between their respective vapors and gases. (3) Air-purifying... reaction with sorbent material in the canister. (c) Pesticide respirators, including all completely...) Front-mounted or back-mounted gas masks; (2) Chin-style gas mask; (3) Chemical cartridge; (4)...

  4. 42 CFR 84.1130 - Respirators; description.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... respective vapors, or from the chemical reaction between their respective vapors and gases. (3) Air-purifying... reaction with sorbent material in the canister. (c) Pesticide respirators, including all completely...) Front-mounted or back-mounted gas masks; (2) Chin-style gas mask; (3) Chemical cartridge; (4)...

  5. Tactical Combat Casualty Care 2007: Evolving Concepts and Battlefield Experience

    DTIC Science & Technology

    2007-11-01

    or thoracic) hemorrhage: no IV fluid resuscitation Head wound patient: Hespan at minimal flow to maintain infusion unless there is concurrent...airway obstruction: chin lift or jaw thrust, nasopharyngeal airway, place casualty in recovery position Surgical cricothyroidotomy (with lidocaine ...laryngeal mask airway /ILMA or Combitube or endotracheal intubation or surgical cricothyroidotomy (with lidocaine if conscious) Spinal immobilization is

  6. MICOM-Based Nowcast/Forecast for Coastal/Open Ocean Regions

    DTIC Science & Technology

    1999-09-30

    of Mi- ami is real-time forecasting of both Eulerian elds, such as temperature and ve- locity, and Lagrangian trajectories, data assimilation ... methods are being developed and evaluated (Chin et al., 1999). The ve primary components of this e ort are (i) MICOM/HYCOM, (ii) satellite-derived sea

  7. Korean Affairs Report No. 299

    DTIC Science & Technology

    2007-11-02

    of service for the people minister of culture and art minister of foreign trade minister of electric power industries minister of communications...Il-song met the visiting delegation from Upper Volta , with the following also present: Ho’ Tarn vice premier; foreign minister Kong Chin-t’ae vice

  8. Sporotrichosis on the face of a 7-year-old boy following a bicycle accident.

    PubMed

    Williams, Blake A; Jennings, Thomas A; Rushing, Erica C; Wirges, Marla; Russell, Brian E

    2013-01-01

    A 7-year-old boy presented with an annular verrucous plaque on the chin of 5 weeks duration. The lesion occurred after a bicycle accident and was unresponsive to antibiotics. Fungal culture grew Sporothrix schenckii. Sporotrichosis should be considered and fungal culture obtained whenever a nodule or plaque fails to respond to initial treatment.

  9. The influence of resistance training experience on the between-day reliability of commonly used strength measures in male youth athletes.

    PubMed

    Weakley, Jonathon; Till, Kevin; Darrall-Jones, Joshua; Roe, Gregory; Phibbs, Padraic; Read, Dale; Jones, Ben

    2017-03-08

    The purpose of this study was to determine the between-day reliability of commonly used strength measures in male youth athletes, while considering resistance training experience. Data were collected on 25 male athletes over two testing sessions, with 72 hours rest between, for the 3RM front squat, chin up and bench press. Subjects were initially categorized by resistance training experience (inexperienced; 6-12 months, experienced; >2 years). The assessment of the between-day reliability (coefficient of variation [CV%]) showed the front squat (experienced: 2.90%; inexperienced: 1.90%), chin up (experienced: 1.70%; inexperienced: 1.90%), and bench press (experienced: 4.50%; inexperienced: 2.40%) were all reliable measures of strength in both groups. Comparison between groups for the error of measurement for each exercise showed trivial differences. When both groups were combined, the CV% for the front squat, bench press, and chin up were 2.50%, 1.80%, and 3.70%, respectively. This study provides scientists and practitioners with the between-day reliability reference data to determine real and practical changes for strength in male youth athletes with different resistance training experience. Furthermore, this study demonstrates that 3RM front squat, chin up and bench press are reliable exercises to quantify strength in male youth athletes.

  10. Soft tissue response to mandibular advancement using 3D CBCT scanning.

    PubMed

    Almeida, R C; Cevidanes, L H S; Carvalho, F A R; Motta, A T; Almeida, M A O; Styner, M; Turvey, T; Proffit, W R; Phillips, C

    2011-04-01

    This prospective longitudinal study assessed the 3D soft tissue changes following mandibular advancement surgery. Cranial base registration was performed for superimposition of virtual models built from cone beam computed tomography (CBCT) volumes. Displacements at the soft and hard tissue chin (n = 20), lower incisors and lower lip (n = 21) were computed for presurgery to splint removal (4-6-week surgical outcome), presurgery to 1 year postsurgery (1-year surgical outcome), and splint removal to 1 year postsurgery (postsurgical adaptation). Qualitative evaluations of color maps illustrated the surgical changes and postsurgical adaptations, but only the lower lip showed statistically significant postsurgical adaptations. Soft and hard tissue chin changes were significantly correlated for each of the intervals evaluated: presurgery to splint removal (r = 0.92), presurgery to 1 year postsurgery (r = 0.86), and splint removal to 1 year postsurgery (r = 0.77). A statistically significant correlation between lower incisor and lower lip was found only between presurgery and 1 year postsurgery (r = 0.55). At 1 year after surgery, 31% of the lower lip changes were explained by changes in the lower incisor position while 73% of the soft tissue chin changes were explained by the hard chin. This study suggests that 3D soft tissue response to mandibular advancement surgery is markedly variable.

  11. The Coast Artillery Journal. Volume 83, Number 2, March-April 1940

    DTIC Science & Technology

    1940-04-01

    with heavy jowls and a stUbborn, dimpled chin, this austere Scotch soldier whom Carlyle thought " sour and intractable" was to build an undying...west-ravines and valleys that presented stiff local obstacles to the advance of a Dough - boy-local lines of resistance for a deeply intrenched enemy

  12. Myanmar, Southeast Asia as seen from STS-59

    NASA Technical Reports Server (NTRS)

    1994-01-01

    View westward from Burma across a finger of India into the Ganges Delta in Bangladesh. The meandering stream in the foreground is the Chindwin River about 100 miles northwest of Mandalay; the stream having tiny meanders is the Myittha; and the stream in sunglint is the Manipur River flowing through the Chin Hills. Extensive hillside fires fill the valleys of Burma with smoke.

  13. [Reconstruction of the mandibular symphysis using a revascularized free flap of the scapula. Surgical technic].

    PubMed

    Mayot, D; Perrin, C; Lindas, P; Dron, K

    1993-01-01

    In cases of surgically removed mandibular symphysis malignancies, the bone and mouth floor were reconstructed using osteo-musculo-cutaneous flaps. In our experience, the latter provide the best results. Removed in dorsal decubitus, they allow floor replacement. During the dissection of the tumor site, we also preserve labial and chin structures, which favours a good restoration of phonation and swallowing.

  14. Interorganizational health care systems implementations: an exploratory study of early electronic commerce initiatives.

    PubMed

    Payton, F C; Ginzberg, M J

    2001-01-01

    Changing business practices, customers needs, and market dynamics have driven many organizations to implement interorganizational systems (IOSs). IOSs have been successfully implemented in the banking, cotton, airline, and consumer-goods industries, and recently attention has turned to the health care industry. This article describes an exploratory study of health care IOS implementations based on the voluntary community health information network (CHIN) model.

  15. Pluridirectional High-Energy Agile Scanning Electron Radiotherapy (PHASER): Extremely Rapid Treatment for Early Lung Cancer

    DTIC Science & Technology

    2014-06-01

    charge could only be measured with 10% accuracy. Additionally, the charge could not be measured in real time and charge drifts due to the gun RF phase...Stathakis S. The Physics of Radiation Therapy. Medical Physics. 2010;37(3):1374-5. 2. Griep C, Davelaar J, Scholten AN, Chin A, Leer JWH. Electron-beam

  16. Characterization and Evaluation of TiB2-AlN Composites for Armor Applications

    DTIC Science & Technology

    2013-09-01

    However, upon examination under the field emission gun scanning electron microscope (SEM), the Stark C AlN powder showed some elongated particles...necessary to definitively conclude the impact of the grain microstructure on the ballistic performance. 20 7. References 1. Chin , E. Army

  17. NEW BEDFORD, PUBLIC MEETING AGENDA AND ...

    EPA Pesticide Factsheets

    2012-06-28

    ... ii]ll iiiumiLi n raipo i: t:<:n:l ::i: chin .Uitniiil: [[iiiini ... r M«iL»«uri, lire™ HIM 'si Ksu: iragimHK-itt iUito gun, .... ... ll:iy tJtun ii^ratinciiniiEi I: or t:.l:i

  18. North Korea’s Nuclear Weapons Development and Diplomacy

    DTIC Science & Technology

    2010-01-05

    earlier than Bosworth; he testified that North Korean Foreign Ministry official, Lee Gun , stated that a peace agreement...September 24, 2008; and Yi Chong- chin , “DPRK official at energy aid talks comments on nuclear verification issue,” Yonhap News Agency, September 19...complete denuclearization. If these 51 Choe Sang- hun , “Tensions rise on Korean peninsula,” New

  19. Linear Lichen Planopilaris of the Face: Case Report and Review.

    PubMed

    Asz-Sigall, Daniel; González-de-Cossio-Hernández, Ana Cecilia; Rodríguez-Lobato, Erika; Ortega-Springall, María Fernanda; Vega-Memije, María Elisa; Arenas Guzmán, Roberto

    2016-09-01

    We describe the case of a 45-year-old man who presented with a 5-month history of unilateral pruritic linear erythematous papules and atrophy on the chin and mandibular area. Dermoscopy showed areas of cicatricial alopecia with absence of follicular openings, perifollicular erythema and pigment. Lichen planopilaris of the face is a rare variant with only 13 cases reported in the literature.

  20. Are We Ready to #MeetTheMoment?

    ERIC Educational Resources Information Center

    Chin, Maisie

    2015-01-01

    CADRE, an organization led by Maisie Chin, is a Human Right to Education Campaign. Between 2005 and 2013, CADRE played a lead role in using grassroots organizing and leadership development to create a seismic shift in public policy, debate, and narrative around school discipline, racial disparities, parents' roles, school climate, and closing the…

  1. NITROTYROSINE ATTENUATES RSV-INDUCED INFLAMMATION IN AIRWAY EPITHELIAL CELLS

    EPA Science Inventory

    Nitrotyrosine attenuates RSV-induced inflammation in airway epithelial cells. Joleen Soukup, Zuowei Li, Susanne Becker and Yuh-Chin Huang. NHEERL, ORD, USEPA, RTP, North Carolina, CEMALB, University of North Carolina, Chapel Hill, North Carolina

    Nitrotyrosine (NO2Tyr) is a...

  2. Dropped head syndrome induced by chemoradiotherapy for nasopharyngeal carcinoma: a case report.

    PubMed

    Hashimoto, Yaichiro; Maebayashi, Katsuya; Izumi, Sachiko; Motegi, Atsushi; Mitsuhashi, Norio

    2012-11-01

    'Dropped head syndrome' (DHS) is characterized by severe weakness of the muscles of the back of the neck, resulting in chin-on-chest deformity. Dropped head syndrome induced by radiotherapy is very rare. We report a case of DHS following chemoradiotherapy with a total of 64.8 Gy in 36 fractions for nasopharyngeal carcinoma.

  3. Source Localization in a Cognitive Radio Environment Consisting of Frequency and Spatial Mobility

    DTIC Science & Technology

    2011-12-01

    accurate initial values to seed the iterative NLSM, ( ),0ktxP is set to the median transmission power of all secondary and primary users in the...and design trade-offs,” IEEE Communications Magazine, vol. 46, no. 4, pp. 32–39, April 2008. [25] I. Guvenc and Chia -Chin Chong, “A Survey on TOA

  4. International Symposium on Chinese Languages and Linguistics Proceedings (4th, Taipei, Taiwan, July 18-20, 1994).

    ERIC Educational Resources Information Center

    Ho, Dah-an, Ed.; Tseng, Chiu-yu, Ed.

    This publication of proceedings, most in English and some in Chinese, of a conference on Chinese languages and linguistics include the following papers: "On Rule Effect and Dialect Classification" (Chin-Chuan Cheng); "Cross-Linguistic Typological Variation, Grammatical Relations, and the Chinese Language" (Bernard Comrie); "Is Chinese a Pragmatic…

  5. EFFECTS OF METAL COMPONENTS IN CONCENTRATED AMBIENT AIR PARTICLES ON PULMONARY INJURY

    EPA Science Inventory

    EFFECTS OF METAL COMPONENTS IN CONCENTRATED AMBIENT AIR PARTICLES ON PULMONARY INJURY. Yuh-Chin Huang, Jackie Stonehuerner, Jackie Carter, Andrew J. Ghio, Robert B. Devlin. NHEERL, US EPA, RTP, NC.
    The mechanisms for cardiopulmonary morbidity associated with exposure to air po...

  6. feature - Office of Cancer Clinical Proteomics Research

    Cancer.gov

    "Cancer is a disease of the genome," noted Lynda Chin, M.D., professor of dermatology, Harvard Medical School and Dana-Farber Cancer Institute. "And understanding the impact of genomic changes in the proteome is critically important for converting genomic knowledge into something that a clinician can use on their patients."

  7. Tracking Speech Sound Acquisition

    ERIC Educational Resources Information Center

    Powell, Thomas W.

    2011-01-01

    This article describes a procedure to aid in the clinical appraisal of child speech. The approach, based on the work by Dinnsen, Chin, Elbert, and Powell (1990; Some constraints on functionally disordered phonologies: Phonetic inventories and phonotactics. "Journal of Speech and Hearing Research", 33, 28-37), uses a railway idiom to track gains in…

  8. ALTERATION OF CARDIAC ELECTRICAL ACTIVITY BY WATER-LEACHABLE COMPONENTS OF RESIDUAL OIL FLY ASH (ROFA)

    EPA Science Inventory

    Alteration of cardiac electrical activity by water-leachable components
    of residual oil fly ash (ROFA)

    Desuo Wang, Yuh-Chin T. Huang*, An Xie, Ting Wang

    *Human Studies Division, NHEERL, US EPA
    104 Mason Farm Road, Chapel Hill, NC 27599
    Department of Basic ...

  9. United States Air Force Research Initiation Program. 1985 Technical Report. Volume 1

    DTIC Science & Technology

    1987-04-01

    Transfer 760-0M6-018 Dr. Barry N. Haack Dr. Je-chin Han 36 Detector Placement and Particle Size Interpretation for a Multiple Ratio Single...Jensen, A. R. (1982). Reaction time and psychometric g. In H. J. Eysenck (Ed.), ^4 model for intelligence. Heidelberg: Springer-Verlag Kanfer, R

  10. Geldanamycin Inhibits Hemorrhage-Induced Increases in Caspase-3 Activity: Role of Inducible Nitric Oxide Synthase

    DTIC Science & Technology

    2016-07-04

    Radiobiology Research Institute, Bethesda; Departments of Radiation Biology , Medicine and of Pharmacology, Uniformed Services University of the Health...Kiang JG, Tsen KT. Biology of hypoxia. Chin J Physiol 49: 223–233, 2006. 1054 GELDANAMYCIN PREVENTS CASPASE INCREASES J Appl Physiol • VOL 103

  11. Comprehension Questioning Small Group Reading Instruction for Urban Students with Learning Disabilities

    ERIC Educational Resources Information Center

    Jones, Valerie

    2012-01-01

    It is evident from reading research that students with learning disabilities (LD) greatly benefit from teacher-student interactions during small group comprehension instruction (e.g., Berkeley, Scruggs, & Mastropieri, 2010). Given that questioning takes up the vast majority of instructional interactions between teachers and students (Chin,…

  12. Comment on 'Quantum teleportation of an arbitrary two-qubit state and its relation to multipartite entanglement'

    SciTech Connect

    Deng Fuguo

    2005-09-15

    The multipartite state in the Rigolin's protocol [Phys. Rev. A 71, 032303 (2005)] for teleporting an arbitrary two-qubit state is just a product state of N Einstein-Podolsky-Rosen pairs in essence, not a genuine multipartite entangled state, and this protocol in principle is equivalent to the Yang-Guo protocol [Chin. Phys. Lett. 17, 162 (2000)].

  13. Comparing Three Jet Rates with and without Hadronic Rindler Horizon

    NASA Astrophysics Data System (ADS)

    Ghaffary, Tooraj

    2017-03-01

    Recently, some researchers, (Sepehri and Shoorvazi Chin. Phys. Lett. 30(2), 021301, [2013]), have considered the effect of Rindler horizon on three jet rate. This paper confirms their results and by comparing usual models with this new model for different energies, shows that regarding Rindler horizon gives us the results which more close to experimental data respect to usual models.

  14. A Randomized Study of Three Interventions for Aspiration of Thin Liquids in Patients with Dementia or Parkinson's Disease

    ERIC Educational Resources Information Center

    Logemann, Jeri A.; Gensler, Gary; Robbins, JoAnne; Lindblad, Anne S.; Brandt, Diane; Hind, Jacqueline A.; Kosek, Steven; Dikeman, Karen; Kazandjian, Marta; Gramigna, Gary D.; Lundy, Donna; McGarvey-Toler, Susan; Miller Gardner, Patricia J.

    2008-01-01

    Purpose: This study was designed to identify which of 3 treatments for aspiration on thin liquids--chin-down posture, nectar-thickened liquids, or honey-thickened liquids--results in the most successful immediate elimination of aspiration on thin liquids during the videofluorographic swallow study in patients with dementia and/or Parkinson's…

  15. Pulmonary veno-occlusive disease

    MedlinePlus

    ... disorder. Alternative Names Pulmonary vaso-occlusive disease Images Respiratory system References Chin K, Channick RN. Pulmonary hypertension. In: Broaddus VC, Mason RJ, Ernst JD, et al, eds. Murray and Nadel's Textbook of Respiratory Medicine . 6th ed. Philadelphia, PA: Elsevier Saunders; 2016: ...

  16. NITROTYROSINATION OF A TUBULIN INDUCES EPITHELIAL BARRIER DYSFUNCTION

    EPA Science Inventory

    Nitrotyrosination of a-Tubulin Induces Epithelial Transport Dysfunction. Yuh-Chin Huang, Lisa Dailey, Wen-Li Zhang and Ilona Jaspers. ORD, Environmental Protection Agency and CEMLB, University of North Carolina

    a-Tubulin undergoes a cyclic removal and readdition of tyrosin...

  17. Descriptions of four species of grenadier fishes of the genera Hymenocephalus and Hymenogadus (Teleostei, Gadiformes, Macrouridae) from the New Zealand region and Tasman Sea, including two new species of Hymenocephalus.

    PubMed

    McMillan, Peter; Iwamoto, Tomio

    2014-08-21

    Two new species of Hymenocephalus are described from the New Zealand region and Tasman Sea. Hymenocephalus fuscus sp. n. has 11-12 pelvic fin rays, is darkly pigmented, with enlarged bony ridges on the dorsal aspects of head, lacks a chin barbel, has few (16-19) gill rakers on inner side of first arch and is similar to other species in the H. aterrimus species group. Hymenocephalus maculicaudus sp. n. has 8 pelvic fin rays, a mid-lateral line of melanophores on body and tail that extends about a head length posterior to anal fin origin, a short (7-16 % HL) chin barbel and is similar to other species in the H. megalops species group. Hymenocephalus nascens has 12-14 pelvic fin rays, lacks a chin barbel, has a mid-lateral stripe of silvery (fresh) or brownish (preserved) pigment running along trunk and tail. Hymenogadus gracilis has a serrated (weak, near tip) first dorsal fin spine, 7-9 pelvic fin rays, long (20-30% HL) chin barbel, and one row of enlarged melanophores along lateral mid-line of the tail. Hymenocephalus nascens and Hymenogadus gracilis are recorded for the first time from the New Zealand region. A key to the known New Zealand species of Hymenocephalus and Hymenogadus is provided. 

  18. Investigating the Impacts of Particle Size and Wind Speed on Brownout

    DTIC Science & Technology

    2015-03-26

    not allow air to move through it easily. Clay makes a soil dense and is hard as concrete when dry. Loam is a nearly even mixture of sand and silt...Desert Dunes, Methuen and Co. Ltd. Chin, M., Rood, R.B, Lin, S., Muller, J., Thompson, A.M., 2000: Atmospheric sulfur cycle simulated in the global

  19. English Teaching & Learning, 2002-2003.

    ERIC Educational Resources Information Center

    English Teaching & Learning, 2003

    2003-01-01

    These four issues contain the following articles: "A Case Documentation of English Instruction at the Elementary School Level: The Cross-Cultural Impact of Native Speaker Teachers" (Hsien-Chin Liou) [written in Chinese]; "A Collaborative Tale with Two Taiwanese EFL College Groups" (Feng-Ming Chi); "A Developmental Study on…

  20. 1. Historic American Buildings Survey E. W. Russell, Photographer, February ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Historic American Buildings Survey E. W. Russell, Photographer, February 6, 1936 WROUGHT IRON GATE WITH CAST IRON ORNAMENTATION, 456 SO. CONCEPTION STREET - 456 South Conception Street (Iron Fence & Gate), (moved to 1802 Old Govt. & 3333 Riviere du Chin), Mobile, Mobile County, AL

  1. Studies Presented to Robert B. Lees by His Students. Papers in Linguistics.

    ERIC Educational Resources Information Center

    Sadock, Jerrold M.; Vanek, Anthony L.

    This volume, dedicated to Professor Robert B. Lees on the occasion of his departure from the University of Illinois, contains 15 papers on a variety of linguistic topics: C. L. Baker, "Problems of Polarity in Counterfactuals"; Lawrence F. Bouton, "Do So: Do+Adverb"; Chin-chuan Cheng, "Domains of Phonological Rule Application"; Joseph F. Foster,…

  2. Stability Operations and State-Building: Continuities and Contingencies

    DTIC Science & Technology

    2008-10-01

    Princeton: Princeton University Press, 1959. 164 114. Cf Gregory Bateson and Mary Catherine Bateson , Angels Fear, Toronto: Bantam Books, 1987; and...their input, especially Gregory Chin, Keith Gomez, and Bill Skidmore. There are many great people at the Small Wars Council who have helped hone

  3. 75 FR 36516 - Addition and Removal of Certain Persons on the Entity List: Addition of Persons Acting Contrary...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-28

    ... (ROIC) wafers to Electronic Components Industries (ECI) of Iran. Fang Yu and Xi'an Xiangyu Aviation.... Sdn Bhd; Austral Aviation Corp.; Jimmy Tok; Mok Chin Fan, a.k.a., Chong Chen Fah; Leigh Michau; Q-SPD...., Chuangye Building 7/1F, 1197 Bin'An Road, Binjiang, Hangzhou, Zhejiang 310052, China; and (3) Xi'an...

  4. Medical Surveillance Monthly Report (MSMR). Volume 8, Number 8, November/December 2002

    DTIC Science & Technology

    2002-12-01

    2002 Legionella pneumophila is a gram-negative bacterium that causes two clinically and epidemio- logically distinct illnesses. Legionnaires ’ disease is...17th edition. ed. Chin J. American Public Health Association. Washington, DC; 2000:281- 3. 2. Legionella pneumophila ( Legionnaires disease ...1998-July 2002.........................................................8 Legionnaires ’ disease in a laboratory worker at a medical treatment facility

  5. Designing an Educational Game, Simulation or Workshop: A Change Theory Perspective.

    ERIC Educational Resources Information Center

    Cryer, Patricia

    1986-01-01

    Presents theoretical perspectives of change of Benne, Chin, Lewin, and Rogers, and draws out strategies that designers of games, simulations, and workshops may find useful. Highlights include rational/empirical, normative/re-educative, and power/coercive strategies; Lewin's force-field model; and Rogers' stage model. (MBR)

  6. Cognitive Models for Learning to Control Dynamic Systems

    DTIC Science & Technology

    2008-09-26

    for Composite Hypotheses”, Technical Report 94.4, Institute for Applications of Mathematics and Informatics, Milan, 1994. [24] I.V. Pavlov , “Sequential...CHANG Yuan-Chin Ivan , Application of sequential interval estimation to adaptive mastery testing, 2005, vol. 70, no4, pp. 685-713. [30] A. Tartakovsky

  7. 76 FR 58035 - Notice of Inventory Completion: U.S. Department of the Interior, Bureau of Reclamation, Phoenix...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-19

    ... Colorado River suggests a long-term history of interaction that stretches back into prehistoric times in... Chemehuevi Reservation, California; Cocopah Tribe of Arizona; Colorado River Indian Tribes of the Colorado... (Ak-Chin) Indian Reservation, Arizona; Gila River Indian Community of the Gila River...

  8. Sovereignty and Inter-governmental Relations with Arizona Indian Tribes--A Report on the Indian Town Hall (2nd, White Mountain Apache Reservation, August 20-22, 1974).

    ERIC Educational Resources Information Center

    Arizona Commission of Indian Affairs, Phoenix.

    Established by the Arizona legislature in 1953 and serving as official link between tribal autonomies and State government, the Arizona Commission of Indian Affairs has recently sponsored its second conference, the proceedings of which constituted this report. Conference participants, forming two panel discussion groups, represented the Ak-Chin,…

  9. 76 FR 77012 - Notice of Inventory Completion: U.S. Department of the Interior, National Park Service, Organ...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-09

    ...; and Tohono O'odham Nation of Arizona. The Cocopah Tribe of Arizona; Colorado River Indian Tribes of the Colorado River Indian Reservation, Arizona and California; Fort Mojave Indian Tribe of Arizona... the Maricopa (Ak Chin) Indian Reservation, Arizona; Cocopah Tribe of Arizona; Colorado River...

  10. Movement Activity Levels on Traditional and Contemporary Playground Structures.

    ERIC Educational Resources Information Center

    Gabbard, Carl P.; LeBlanc, Elizabeth

    This study investigated playground activity levels of children in grades K-4 and compared levels of use of traditional and creative playground apparatus. The traditional playground area consisted of climbing bars, slides, ladders, chin bars, swings, see saws, and a merry-go-round. The creative playground contained tire hurdles, tire walk, tire…

  11. Quantum kung fu

    NASA Astrophysics Data System (ADS)

    Flicker, Felix

    2014-07-01

    If someone puts you in an armlock, what should you do? If you happen to be a martial artist well-practised in the art of joint manipulation, or chin na, you will know the answer already: there is one simple move that will allow you to turn the tables on your aggressor, leaving them on the wrong end of a throw.

  12. The Evaluation and Treatment of Aggression Maintained by Attention and Automatic Reinforcement.

    ERIC Educational Resources Information Center

    Thompson, Rachel H.; Fisher, Wayne W.; Piazza, Cathleen C.; Kuhn, David E.

    1998-01-01

    A study used direct and indirect methods to assess and treat several topographies of the aggression of a 7-year-old boy with severe mental retardation and pervasive personality disorder. Functional communication training with extinction reduced all forms of aggression except chin grinding, which was reduced by an alternative treatment. (Author/CR)

  13. Differential Amplifier Circuits Based on Carbon Nanotube Field Effect Transistors (CNTFETs)

    DTIC Science & Technology

    2010-04-01

    Differential Amplifier Circuits Based on Carbon Nanotube Field Effect Transistors ( CNTFETs ) by Matthew Chin and Dr. Stephen Kilpatrick...20783-1197 ARL-TR-5151 April 2010 Differential Amplifier Circuits Based on Carbon Nanotube Field Effect Transistors ( CNTFETs ) Dr...AND SUBTITLE Differential Amplifier Circuits Based on Carbon Nanotube Field Effect Transistors ( CNTFETs ) 5a. CONTRACT NUMBER 5b. GRANT NUMBER

  14. Insecure Commitment and Resistance: An Examination of Change Leadership, Self-Efficacy, and Trust on the Relationship between Job Insecurity, Employee Commitment, and Resistance to Organizational Change

    ERIC Educational Resources Information Center

    Smith, Robert Elijah

    2013-01-01

    This study was designed to examine the mediation role of self-efficacy and the moderating roles of change leadership strategy and trust on the change attitudes of job insecure employees. Using job insecurity theory (Greenhalgh, 1983), Chin & Benne's (1961) seminal classification of change leadership strategies and the tripartite model of…

  15. High-Resolution Global Modeling of the Effects of Subgrid-Scale Clouds and Turbulence on Precipitating Cloud Systems

    SciTech Connect

    Bogenschutz, Peter; Moeng, Chin-Hoh

    2015-10-13

    The PI’s at the National Center for Atmospheric Research (NCAR), Chin-Hoh Moeng and Peter Bogenschutz, have primarily focused their time on the implementation of the Simplified-Higher Order Turbulence Closure (SHOC; Bogenschutz and Krueger 2013) to the Multi-scale Modeling Framework (MMF) global model and testing of SHOC on deep convective cloud regimes.

  16. The effect of bone displacement operations on facial soft tissues.

    PubMed

    Habib, Ali; Hisham, Ahmed

    2013-01-01

    A novel biomechanical model for face soft tissue (skin, mucosa, and muscles) is introduced to investigate the effect of mandible and chin bone displacement on the overall appearance of the patient's face. Nonlinear FE analysis is applied to the model and the results obtained are used to help surgeons to decide the amount of displacement required.

  17. Investigation of Primary Students' Motivation Levels towards Science Learning

    ERIC Educational Resources Information Center

    Sevinc, Betul; Ozmen, Haluk; Yigit, Nevzat

    2011-01-01

    The present research was conducted with 518 students enrolled at the 6th, 7th and 8th classes of primary schools. A likert-type scale developed by Tuan, Chin and Shieh (2005) and translated into Turkish by Yilmaz and Cavas (2007) was used to examine the motivation levels of students towards science learning. Research findings revealed that gender,…

  18. Adaptation of the Students' Motivation towards Science Learning (SMTSL) Questionnaire in the Greek Language

    ERIC Educational Resources Information Center

    Dermitzaki, Irini; Stavroussi, Panayiota; Vavougios, Denis; Kotsis, Konstantinos T.

    2013-01-01

    The present study aimed at adapting in the Greek language the Students' Motivation Towards Science Learning (SMTSL) questionnaire developed by Tuan, Chin, and Shieh ("INT J SCI EDUC" 27(6): 639-654, 2005a) into a different cultural context, a different age group, that is, in university students and with a focus on physics learning. Three…

  19. Identification of Physically Underdeveloped Pupils: Activities to Improve Their Performance.

    ERIC Educational Resources Information Center

    President's Council on Physical Fitness and Sports, Washington, DC.

    Screening tests consisting of observation procedures and simple physical exercises requiring only a chinning bar, stopwatch, and record forms are suggested for identifying pupils aged ten to seventeen who are underdeveloped in strength, flexibility, agility, or cardiorespiratory endurance. Classes should be divided into pairs with one pupil acting…

  20. STS-53 Pilot Cabana adjusts CCA during JSC launch emergency egress training

    NASA Technical Reports Server (NTRS)

    1992-01-01

    STS-53 Discovery, Orbiter Vehicle (OV) 103, Pilot Robert D. Cabana, wearing launch and entry suit (LES), adjusts communications carrier assembly (CCA) chin strap and microphones before donning his helmet. Cabana is preparing for launch emergency egress bailout procedures in JSC's Mockup and Integration Laboratory (MAIL) Bldg 9NE.

  1. DETECT: A MATLAB Toolbox for Event Detection and Identification in Time Series, with Applications to Artifact Detection in EEG Signals

    DTIC Science & Technology

    2013-04-24

    newborn infants [5] as well as the monitoring of fatigue in prolonged driving simulations [6]. In many of these settings, the experiments may last...Automatic burst detection for the EEG of the preterm infant . Physiol Meas 32: 1623. doi:10.1088/0967–3334/32/10/010. 6. Chin-Teng Lin, Che-Jui Chang, Bor

  2. [Forum on tissue expansion. Repair of sequelae of facial burns by cervical cutaneous expansion].

    PubMed

    Foyatier, J L; Comparin, J P; Latarjet, J; Delay, E; Spitalier, P; Masson, C L

    1993-02-01

    Burn scars of the lower part of the face are a difficult problem in plastic surgery. Full thickness skin graft or local flaps usually give poor cosmetic result. Over the last 5 years, we used 24 skin expanders in the neck area to cover burn scars of the chin and jaw. Discussion of the method and 4 cases are reported.

  3. Simulation of Geometric Effects on Double-Gate Field Emission Devices

    DTIC Science & Technology

    2000-07-01

    and Tsung-Yu Yang Department of Electronic Engineering I-Shou University Ta-Hsu Hsiang , Kaohsiung County, Taiwan, R.O.C. ABSTRACT We report a study...1997. 3. Chi-Chang Wang, Jiin- Chuan , Chin-Ming Huang, IVMC󈨤, pp. 557, 1996. 4. Xieqing Zhu and Eric Munro, J. Van. Sci. Technol. B, 7, no 6, pp. 1862

  4. Toward a Paradigm of Educational Change: The Role of Management Information Systems.

    ERIC Educational Resources Information Center

    Simonds, Richard Shelton

    The paradigm and model presented in this paper, influenced by the Havelock's "linkage" model and Chin's "changing" model, aim to assist educators in determing directions of change using a selection of managerial and behavioral techniques, and to regulate the rate of change using management information and control systems. The generic paradigm…

  5. Effects of Manual Negative Accentuated Resistance on Strength and/or Muscular Endurance.

    ERIC Educational Resources Information Center

    Johnson, Robert M.

    The purpose of this study was to determine the effects of manual negative accentuated resistance on strength and/or muscular endurance. Three strength and/or muscular endurance tests were administered to male and female physical education majors enrolled in a required exercise class at the beginning and end of the semester. Push-ups, chin-ups, and…

  6. VANADYL SULFATE INHIBITS NO PRODUCTION BY DIFFERENTIALLY REGULATING SERINE/THREONINE PHOSPHORYLATION OF ENOS

    EPA Science Inventory

    VANADYL SULFATE INHIBITS NO PRODUCTION BY DIFFERENTIALLY REGULATING SERINE/THREONINE PHOSPHORYLATION OF eNOS.

    Zhuowei Li, Jacqueline D. Carter, Lisa A. Dailey, Joleen Soukup, Yuh-Chin T. Huang. CEMALB, University of North Carolina and NHEERL, US EPA, Chapel Hill, North Ca...

  7. VANADL SULFATE INHIBITS NO PRODUCTION BY DIFFERENTIALLY REGULATING SERINE/THREONINE PHOSPHORYLATION OF ENOS

    EPA Science Inventory

    VANADYL SULFATE INHIBITS NO PRODUCTION BY DIFFERENTIALLY REGULATING SERINE/THREONINE PHOSPHORYLATION OF eNOS. Zhuowei Li, Jacqueline D. Carter, Lisa A. Dailey, Joleen Soukup, Yuh-Chin T. Huang. CEMALB, University of North Carolina and ORD, US EPA, Chapel Hill, North Carolina
    V...

  8. Papillary haemangioma: a case report of multiple facial location.

    PubMed

    Rammeh, S; Fazaa, B; Ajouli, W; Labbene, I; Kharfi, M; Zermani, R

    2014-06-01

    Papillary haemangiomas were recently defined as morphologically distinct and benign cutaneous haemangiomas showing a predominantly intravascular capillary proliferation within dilated thin-walled dermal blood vessels. We describe the case of a 45-year-old woman who presented with multiple eruptive red-bluish raised papules and nodules distributed over the skin of the chin that were related to a papillary haemangioma.

  9. Fundreds in Arkansas: An Interdisciplinary Collaboration

    ERIC Educational Resources Information Center

    La Porte, Angela M.

    2010-01-01

    This article discusses Fundreds in Arkansas, an interactive cooperative in Arkansas to promote and support Mel Chin's nationwide interdisciplinary artwork, Operation Paydirt (The Fundred Dollar Bill Project). The artwork involves communities and educational institutions across the country, healthcare professionals, engineers, urban planners, and…

  10. Comparison of gene expression profiles in cultivated peanut (Arachis hypogaea) under strong artificial selection

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Over the past five decades, cultivated peanut in China has been subjected to strong artificial selection in breeding programs. To investigate the impact of artificial selection on expression diversity, we compared gene expression profiles in pod and leaf of five widespread cultivars in Southern Chin...

  11. Neck pain

    MedlinePlus

    ... neck. If neck pain involves compression of your nerves, you may feel numbness, tingling, or weakness in your arm or ... When to Contact a Medical Professional ... fever and headache, and your neck is so stiff that you cannot touch your chin to your chest. This may be ...

  12. One-trial object recognition memory in the domestic rabbit (Oryctolagus cuniculus) is disrupted by NMDA receptor antagonists.

    PubMed

    Hoffman, Kurt Leroy; Basurto, Enrique

    2013-08-01

    The spontaneous response to novelty is the basis of one-trial object recognition tests for the study of object recognition memory (ORM) in rodents. We describe an object recognition task for the rabbit, based on its natural tendency to scent-mark ("chin") novel objects. The object recognition task comprised a 15min sample phase in which the rabbit was placed into an open field arena containing two similar objects, then removed for a 5-360min delay, and then returned to the same arena that contained one object similar to the original ones ("Familiar") and one that differed from the original ones ("Novel"), for a 15min test phase. Chin-marks directed at each of the objects were registered. Some animals received injections (sc) of saline, ketamine (1mg/kg), or MK-801 (37μg/kg), 5 or 20min before the sample phase. We found that chinning decreased across the sample phase, and that this response showed stimulus specificity, a defining characteristic of habituation: in the test phase, chinning directed at the Novel, but not Familiar, object was increased. Chinning directed preferentially at the novel object, which we interpret as novelty-induced sensitization and the behavioral correlate of ORM, was promoted by tactile/visual and spatial novelty. ORM deficits were induced by pre-treatment with MK-801 and, to a lesser extent, ketamine. Novel object discrimination was not observed after delays longer than 5min. These results suggest that short-term habituation and sensitization, not long-term memory, underlie novel object discrimination in this test paradigm.

  13. Photographic Facial Soft Tissue Analysis by Means of Linear and Angular Measurements in an Adolescent Persian Population

    PubMed Central

    Moshkelgosha, Vahid; Fathinejad, Sheida; Pakizeh, Zeinab; Shamsa, Mohammad; Golkari, Ali

    2015-01-01

    Objective : To obtain objective average measurements of the profile and frontal facial soft tissue to be used as a guide for aesthetic treatment goals. Methods and Materials : This observational study included 110 females and 130 males high school students aged 16-18 years. None of the subjects had any facial deformities. All of them and their parents gave consent to take part in this study. In each case, two standard photographs of profile and frontal views were taken 27 landmarks were digitized on photographs. The mean, standard deviation, and range for a total of 43 facial indices were calculated digitally by computer software. The Student’s t-test was used to compare males and females. Results : The ratio between the lower and middle facial thirds was one to one, but the height of the upper facial third was proportionally smaller than the other two-thirds in both sexes. Boys had greater nasal length, depth, and prominence than girls with statistically significant differences. Both upper and lower lips were more prominent in girls than in boys. All measurements of the chin showed sexual dimorphism characterized by greater chin height and prominence and deeper mentolabial sulcus. Boys had greater facial dimensions than girls. Mouth width, nasal base width, and intercanthal distance were significantly greater in boys. Conclusion : The labial, nasal, and chin areas showed sexual dimorphism in most of the parameters used in this study. Boys had larger faces, greater facial heights, longer nasal, labial, and chin lengths, and greater nasal, labial, and chin prominence. PMID:26464606

  14. Properties of soluble and membrane bound dopamine-beta-monooxygenase from bovine adrenal medulla cross-linked with dimethyl suberimidate.

    PubMed

    Miras-Portugal, M T; Millaruelo, A; Vara, F

    1980-12-10

    Bovine dopamine-beta-monooxygenase from chromaffin granules in its soluble and membrane-bound forms was cross-linked with the bifunctional reagent dimethyl suberimidate, and its structural and kinetic properties were studied. 1. The cross-linking reaction does not affect the activity of soluble dopamine-beta-monooxygenase; it produces a ten percent inactivation in the membrane-bound enzyme, possibly because the linkage to other membrane proteins hinders its activity. 2. The soluble dopamine-beta-monooxygenase reaction mixture was analyzed by sodium dodecyl sulfate gel electrophoresis, showing appreciable amounts of dimer and tetramer, but only small amounts of trimer. In membrane-bound dopamine-beta-monooxygenase, subjected to the same treatment, appreciable amounts of dimer and higher aggregates were found. 3. The kinetic properties of soluble dopamine-beta-monooxygenase after the crosslinking reaction are the same as those of the native enzyme, with a ping-pong kinetic mechanism and the same real Michaelis constants for tyramine and ascorbate: KmT = 0.36 mM and KmA = 0.32 mM. Membrane-bound dopamine-beta-monooxygenase does not present a ping-pong mechanism before or after cross-linking; its real Michaelis constants are slightly modified by the cross-linking reaction: KmT = 0.4 mM and KMA = 0.4 mM.

  15. Action-specific effects in a social context: others' abilities influence perceived speed.

    PubMed

    Witt, Jessica K; Sugovic, Mila; Taylor, J Eric T

    2012-06-01

    According to the action-specific account of perception, perceivers see the environment relative to their ability to perform the intended action. For example, in a modified version of the computer game Pong, balls that were easier to block looked to be moving slower than balls that were more difficult to block (Witt & Sugovic, 2010). It is unknown, however, if perception can be influenced by another person's abilities. In the current experiment, we examined whether another person's ability to block a ball influenced the observer's perception of ball speed. Participants played and observed others play the modified version of Pong where the task was to successfully block the ball with paddles that varied in size, and both the actor and observer estimated the speed of the ball. The results showed that both judged the ball to be moving faster when it was harder to block. However, the same effect of difficulty on speed estimates was not found when observers watched a computer play, suggesting the effect is specific to people and not to the task. These studies suggest that the environment can be perceived relative to another person's abilities.

  16. Decentralized Cooperation Strategies in Two-Dimensional Traffic of Cellular Automata

    NASA Astrophysics Data System (ADS)

    Fang, Jun; Qin, Zheng; Chen, Xi-Qun; Leng, Biao; Xu, Zhao-Hui; Jiang, Zi-Neng

    2012-12-01

    We study the two-dimensional traffic of cellular automata using computer simulation. We propose two type of decentralized cooperation strategies, which are called stepping aside (CS-SA) and choosing alternative routes (CS-CAR) respectively. We introduce them into an existing two-dimensional cellular automata (CA) model. CS-SA is designed to prohibit a kind of ping-pong jump when two objects standing together try to move in opposite directions. CS-CAR is designed to change the solution of conflict in parallel update. CS-CAR encourages the objects involved in parallel conflicts choose their alternative routes instead of waiting. We also combine the two cooperation strategies (CS-SA-CAR) to test their combined effects. It is found that the system keeps on a partial jam phase with nonzero velocity and flow until the density reaches one. The ratios of the ping-pong jump and the waiting objects involved in conflict are decreased obviously, especially at the free phase. And the average flow is improved by the three cooperation strategies. Although the average travel time is lengthened a bit by CS-CAR, it is shorten by CS-SA and CS-SA-CAR. In addition, we discuss the advantage and applicability of decentralized cooperation modeling.

  17. Summer Crop Classification by Multi-Temporal COSMO-SkyMed® Data

    NASA Astrophysics Data System (ADS)

    Guarini, Rocchina; Bruzzone, Lorenzo; Santoni, Massimo; Vuolo, Francesco; Luigi, Dini

    2016-08-01

    In this study, we propose a multi-temporal and multi- polarization approach to discriminate different crop types in the Marchefel region, Austria. The sensitivity of X-band COSMO-SkyMed® (CSK®) data with respect to five crop classes, namely carrot, corn, potato, soybean and sugarbeet is investigated. In particular, the capabilities of dual-polarization (StripMap PingPong) HH/HV, and single-polarization (StripMap Himage), HH and VH, in distinguishing among the five crop types are evaluated. A total of twenty-one Himage and ten PingPong images were acquired in a seven-months period, from April to October 2014. Therefore, the backscattering coefficient was extracted for each dataset and the classification was performed using a pixel-based support vector machine (SVM) approach. The accuracy of the obtained crop classifications was assessed by comparing them with ground truth. The dual-polarization results are contrasted between the HH and HV polarization, and with single-polarization ones (HH and VH polarizations). The best accuracy is obtained by using time-series of StripMap Himage data, at VH polarization, covering the whole season period.

  18. Kinetic mechanisms of the A and B isozymes of O-acetylserine sulfhydrylase from Salmonella typhimurium LT-2 using the natural and alternative reactants.

    PubMed

    Tai, C H; Nalabolu, S R; Jacobson, T M; Minter, D E; Cook, P F

    1993-06-29

    The resonance-stabilized quinonoid 5-mercapto-2-nitrobenzoate (TNB) is a substrate for O-acetylserine sulfhydrylase-A (OASS-A) and -B (OASS-B), giving rise to the product S-(3-carboxy-4-nitrophenyl)-L-cysteine (S-CNP-cysteine) as confirmed by ultraviolet-visible and 1H NMR spectroscopies. A comparison of the kinetics of OASS-A and OASS-B indicates that the mechanism proceeds predominantly via a bi-bi ping pong kinetic mechanism as suggested by an initial velocity pattern consisting of parallel lines at low concentrations of reactants, but competitive inhibition by both substrates as the reactant concentrations are increased. Thus, in the first half-reaction, O-acetyl-L-serine (OAS) or beta-chloro-L-alanine (BCA) is converted to alpha-aminoacrylate in Schiff base with the active site pyridoxal 5'-phosphate, while in the second half-reaction cysteine (with sulfide as the reactant) or S-CNP-cysteine (with TNB as the reactant) is formed. The ping pong mechanism is corroborated by a qualitative and quantitative analysis of product and dead-end inhibition. Product inhibition by acetate is S-parabolic noncompetitive. These data are consistent with acetate reversing the first half-reaction and producing more free enzyme to which acetate may also bind. Thus, there may be some randomness to the mechanism at high concentrations of the nucleophilic substrate.

  19. Orocutaneous Fistula or Traumatic Infectious Skin Lesion: A Diagnostic Dilemma

    PubMed Central

    Vermani, Mayank; Kalia, Vimal; Singh, Sumita; Garg, Sunny; Aggarwal, Shweta; Khurana, Richa; Kalra, Geeta

    2015-01-01

    Orocutaneous fistula (OCF) (of dental origin) is an uncommon but well-described condition in the literature. These are often misdiagnosed by physicians and dentists. Careful selection of investigating modality is important in case of diagnostically challenging cases. A 19-year-old female came with a complaint of a lesion on the chin reported with h/o trauma with the impact on chin presented as diagnostic dilemma because of unusual case history and clinical examination. Commonly used radiographic investigations like IOPA and orthopantomograph did not resolve the dilemma whereas advanced imaging modality like CT scan, 3D volume imaging, and contrast enhanced CT played an important role in the diagnosis of OCF and selecting the treatment plan. PMID:26618009

  20. Local ICA for the Most Wanted face recognition

    NASA Astrophysics Data System (ADS)

    Guan, Xin; Szu, Harold H.; Markowitz, Zvi

    2000-04-01

    Facial disguises of FBI Most Wanted criminals are inevitable and anticipated in our design of automatic/aided target recognition (ATR) imaging systems. For example, man's facial hairs may hide his mouth and chin but not necessarily the nose and eyes. Sunglasses will cover the eyes but not the nose, mouth, and chins. This fact motivates us to build sets of the independent component analyses bases separately for each facial region of the entire alleged criminal group. Then, given an alleged criminal face, collective votes are obtained from all facial regions in terms of 'yes, no, abstain' and are tallied for a potential alarm. Moreover, and innocent outside shall fall below the alarm threshold and is allowed to pass the checkpoint. Such a PD versus FAR called ROC curve is obtained.

  1. Sex and age identification of palila

    USGS Publications Warehouse

    Jeffrey, J.J.; Fancy, S.G.; Lindsey, G.D.; Banko, P.C.; Pratt, T.K.; Jacobi, J.D.

    1993-01-01

    Methods to sex and age Palila (Loxioides bailleui), an endangered Hawaiian finch restricted to subalpine woodlands on Hawai'i, were identified on the basis of measurements and plumage characteristics of 17 museum specimens and 96 known-age, live Palila. Palila undergo a single annual molt during September-December following the breeding season. Presence of a complete or partial wingbar distinguishes hatch-year and second-year Palila from after-second-year birds. Adult male Palila are distinguished from females by a distinct napeline and lt 30% gray feathers intermixed with yellow feathers on the head. The black or gray feathers of the lores and chin of males are darker than those on the back, whereas the lores and chin of females are lighter or of the same shade as back feathers.

  2. Managing the Cutaneous Sinus Tract of Dental Origine

    PubMed Central

    Janev, Edvard; Redzep, Enis

    2016-01-01

    BACKGROUND: Draining cutaneous sinus tract in chin area may be caused by chronic periapical dental infections. Misdiagnosis of these lesions usually leads to destructive invasive treatment of the sinus tract that is not correct and curative. CASE REPORT: A 31-year-old male patient referred to us with a chronically draining lesion on his chin. The lesion previously was misdiagnosed by medical doctors and had undergone two times surgery with a focus on the skin lesion and had received antibiotic therapy for a prolonged period of time. After clinical and radiologic examination the dental origin of the lesion was evident and proper endodontic and surgical treatment was performed. Three months later, after the treatment, the lesion showed total healing and reoccurrence occurred. CONCLUSION: The key to successful treatment of cutaneous sinus tract of dental origin must be in appropriate communication between the dentist and the physician in order to achieve correct diagnosis and therapy in such cases. PMID:27703580

  3. The "baseball cap orthosis": a simple solution for dropped head syndrome.

    PubMed

    Fast, Avital; Thomas, Mark A

    2008-01-01

    Dropped head syndrome (DHS) is a well-recognized condition characterized by gradual sagging of the head. At the extreme, the condition may lead to a "chin on chest deformity" where the chin rests on the chest wall and the patient is unable to look straight ahead. Dropped head syndrome tends to develop in patients with severe weakness of the neck extensors. Various neuromuscular disorders and surgical procedures may compromise the stability of the cervical spine and lead to this disorder. The condition may severely compromise the patient's quality of life and result in significant disability. A simple device-the "baseball cap orthosis"-was developed to help patients maintain their head in the upright position. Two patients with DHS who were provided with the baseball cap orthosis are presented.

  4. Penning trap mass measurement of 72Br

    NASA Astrophysics Data System (ADS)

    Valverde, A. A.; Bollen, G.; Cooper, K.; Eibach, M.; Gulyuz, K.; Izzo, C.; Morrissey, D. J.; Ringle, R.; Sandler, R.; Schwarz, S.; Sumithrarachchi, C. S.; Villari, A. C. C.

    2015-03-01

    The Low Energy Beam and Ion Trap (LEBIT) Penning trap mass spectrometer was used to perform an improved-precision mass measurement of 72Br and the low-lying isomeric state, Brm72, giving mass excesses of -59 062.2 (1.0 )keV and -58 960.9 (1.2 )keV , respectively. These values are consistent with the values from the 2012 atomic mass evaluation [Chin. Phys. C 36, 1603 (2012), 10.1088/1674-1137/36/12/003] and the Nubase2012 evaluation of nuclear properties [Chin. Phys. C 36, 1157 (2012), 10.1088/1674-1137/36/12/001]. The uncertainties on the mass of the ground state and isomeric state have been reduced by a factor of seven.

  5. A study of the SMC cluster NGC 330

    NASA Astrophysics Data System (ADS)

    Chiosi, C.; Vallenari, A.; Fagotto, F.; Bertelli, G.; Bressan, A.; Nasi, E.

    1993-03-01

    We analyze the properties of the SMC cluster NGC 330 on the basis of a new CMD and of published effective temperatures and bolometric magnitudes for a smaller sample of stars (Caloi et al 1993, Stothers & Chin 1992a,b) to check for the kind of mixing taking place in massive stars. The existence of a few stars in the so-called HR gap led Stothers & Chin (1993) to claim that only models with semiconvective mixing and OPAL could match the HR diagram, whereas induced Caloi et al (1993) to conclude that neither semiconvective nor overshoot models are suited. The careful analysis of this cluster with new stellar models indicates that 1) models with convective overshoot and models with semiconvection can both explain the gross features of the HR diagram, 2) models with overshoot ought to be preferred.

  6. A study of the SMC cluster NGC 330.

    NASA Astrophysics Data System (ADS)

    Chiosi, C.; Vallenari, A.; Fagotto, F.; Bertelli, G.; Bressan, A.; Nasi, E.

    The authors analyze the properties of the SMC cluster NGC 330 on the basis of a new CMD and of published effective temperatures and bolometric magnitudes for a smaller sample of stars (Caloi et al., 1993; Stothers and Chin, 1992) to check for the kind of mixing taking place in massive stars. The existence of a few stars in the so-called HR gap led Stothers and Chin (1993) to claim that only models with semiconvective mixing and OPAL could match the HR diagram, whereas Caloi et al. (1993) induced to conclude that neither semiconvective nor overshoot models are suited. The careful analysis of this cluster with new stellar models indicates that (1) models with convective overshoot and models with semiconvection can both explain the gross features of the HR diagram, (2) models with overshoot ought to be preferred.

  7. Effects of asymmetric sitting on spinal balance.

    PubMed

    Woo, Hee Soon; Oh, Jong Chi; Won, Sung Yoon

    2016-01-01

    [Purpose] To investigate the effects of two common asymmetric sitting positions on spinal balance. [Subjects and Methods] Thirty-seven healthy subjects in their twenties were enrolled and randomly divided into two groups. Asymmetric positions of resting the chin on a hand and crossing the legs were performed by each group for 1 hour. After 1 hour, the subjects lay in the supine position again and spinal imbalance was measured using a device. [Results] After 1 hour of resting with the chin on a hand, sagittal imbalance, coronal imbalance, pelvic obliquity and lordosis angle presented spinal imbalance worsening of 1 hour of crossing legs, sagittal imbalance, pelvic torsion showed in mainly learned spinal imbalance living. [Conclusion] Good posture could be an innate ability, however it through habits. So this study is meaningful from the perspective of the importance of good posture.

  8. A case of linear lichen planus pigmentosus.

    PubMed

    Seo, Jong Keun; Lee, Hyun Jae; Lee, Deborah; Choi, Joon Hee; Sung, Ho-Suck

    2010-08-01

    Lichen planus pigmentosus (LPP) is chronic pigmentary disorder that shows diffuse or reticulated hyperpigmented, dark brown macules on the sun-exposed areas such as the face, neck and other flexural folds. Clinically, it is different from classical lichen planus because LPP has a longer clinical course and it manifests with dark brown macules. In case of LPP, involvement of the scalp, nail or mucosal area is rare. The histopathological findings of the lesions show an atrophic epidermis, the presence of melanophages and a vacuolar alteration of the basal cell layer with a sparse lymphohistiocytic lichenoid infiltration. Although there have been a few reports of LPP, there have only 3 cases of linear LPP along the lines of Blaschko in the Korean dermatologic literature. Our patient had lesions on the neck and chin with a linear pattern. In this report, we describe a very rare case of LPP with a linear distribution related to Blaschko's lines on the neck and chin areas.

  9. Lightweight device to stimulate and monitor human vestibulo-ocular reflex

    NASA Technical Reports Server (NTRS)

    McStravick, M. Catherine (Inventor); Proctor, David R. (Inventor); Wood, Scott J. (Inventor)

    1989-01-01

    A helmet formed of a rigid shell is disclosed. The shell is lined with several air filled bladders to contact firmly the head of a user. The shell has a rigid chin bar supporting a bite bar connected fixedly to a mouthpiece bearing against the teeth and hard palate to firmly anchor the helmet without movement. The outer shell surface supports various air pumping bulbs and accelerometers. Separate left and right visor pivot on the side guided in a central tongue and groove track to move optical lens mounts into the user's field of vision. The chin bar is connected to the shell by a pair of releasable clasps. A safety lanyard connects to the clasps to quickly pull pins from the clasps to enable quick release in case of motion sickness.

  10. Gnatophyma - A rare form of rosacea*

    PubMed Central

    de Macedo, Ana Carolina Lisboa; Sakai, Fernanda Dias Pacheco; de Vasconcelos, Rossana Cantanhede Farias; Duarte, Artur Antonio

    2012-01-01

    Phyma is the last stage of rosacea and is due to chronic inflammation and edema. It can affect nose (rhinophyma), chin (gnatophyma), forehead (metophyma), ears (otophyma) and eyelids (blepharophyma). Rhinophyma is the most frequent location and there are few reports about gnatophyma. We report the case of a female patient, 41 years old, who had an infiltrated, erythematous, edematous plaque around the chin and lower lip for two years. Histopathology showed perivascular lymphocytic infiltrate, hypertrophied follicles and sebaceous glands, dilated vessels and fibrosis. She was treated with oral tetracycline, oral ivermectin and metronidazole cream with a satisfactory response. The clinical, histopathological and therapeutic response correlation confirmed the diagnosis of gnatophyma, a rare variant of phyma. PMID:23197212

  11. Sensory Hairs in the Bowhead Whale, Balaena mysticetus (Cetacea, Mammalia).

    PubMed

    Drake, Summer E; Crish, Samuel D; George, John C; Stimmelmayr, Raphaella; Thewissen, J G M

    2015-07-01

    We studied the histology and morphometrics of the hairs of bowhead whales (Balaena mysticetus). These whales are hairless except for two patches of more than 300 hairs on the rostral tip of the lower lip and chin, the rostral tip of the upper lip, and a bilateral row of approximately ten hairs caudal to the blowhole. Histological data indicate that hairs in all three of these areas are vibrissae: they show an outermost connective tissue capsule, a circumferential blood sinus system surrounding the hair shaft, and dense innervation to the follicle. Morphometric data were collected on hair diameters, epidermal recess diameters, hair follicle length, and external hair lengths. The main difference between the hairs in the different regions is that blowhole hairs have larger diameters than the hairs in the chin and rostrum regions. We speculate that the hair shaft thickness patterns in bowheads reflect functional specializations.

  12. Immediate 3-dimensional ridge augmentation after extraction of periodontally hopeless tooth using chinblock graft

    PubMed Central

    Desai, Ankit; Thomas, Raison; A. Baron, Tarunkumar; Shah, Rucha; Mehta, Dhoom-Singh

    2015-01-01

    Background The aim of the present study was to evaluate clinically and radiographically, the efficacy of immediate ridge augmentation to reconstruct the vertical and horizontal dimensions at extraction sites of periodontally hopeless tooth using an autogenous chin block graft. Material and Methods A total of 11 patients (7 male & 4 female) with localized advanced bone loss around single rooted teeth having hopeless prognosis and indicated for extraction were selected for the study. The teeth were atraumatically extracted and deficient sites were augmented using autogenous chin block graft. Parameters like clinically soft tissue height - width and also radiographic ridge height -width were measured before and 6 months after augmentation. Obtained results were tabulated and analysed statistically. Results After 6 months of immediate ridge augmentation, the mean gain in radiographic vertical height and horizontal width was 7.64 + 1.47 mm (P = 0.005) and 5.28 + 0.46 mm (P = 0.007) respectively which was found to be statistically significant (P < 0.05). Mean change of width gain of 0.40mm and height loss of 0.40mm of soft tissue parameters, from the baseline till completion of the study at 6 months was observed. Conclusions The present study showed predictable immediate ridge augmentation with autogenous chin block graft at periodontally compromised extraction site. It can provide adequate hard and soft tissue foundation for perfect 3-Dimensional prosthetic positioning of implant in severely deficient ridges. Key words:Immediate ridge augmentation, periondontally hopeless tooth, autogenous chin graft, dental implant. PMID:26644832

  13. Semi-Classical Dirac Vacuum Polarisation in a Scalar Field

    NASA Astrophysics Data System (ADS)

    Lampart, Jonas; Lewin, Mathieu

    2016-08-01

    We study vacuum polarisation effects of a Dirac field coupled to an external scalar field and derive a semi-classical expansion of the regu-larised vacuum energy. The leading order of this expansion is given by a classical formula due to Chin, Lee-Wick and Walecka, for which our result provides the first rigorous proof. We then discuss applications to the non-relativistic large-coupling limit of an interacting system, and to the stability of homogeneous systems.

  14. Lagrangian Turbulence and Transport in Semi-Enclosed Basins and Coastal Regions

    DTIC Science & Technology

    2003-09-30

    involved in the application of the assimilation methods ; Leonid Piterbarg (USC) in the mathematical formulation of the method; Milena Veneziani (RSMAS...MPO) in the analysis of Lagrangian data; Mike Chin (RSMAS/MPO) in the comparison of the assimilation methods . WORK COMPLETED 1) Application of...Lagrangian statistics even in presence of coherent structures. TRANSITIONS Lagrangian data assimilation methods are planned to be used in the

  15. Data Quality Problems in Army Logistics, Classification, Examples, and Solutions.

    DTIC Science & Technology

    1996-01-01

    Eden , and Folkeson (1995). 5The other services also have logistics data-quality problems to deal with. See Abell and Finnegan (1993). 6See Energy...component of the Army’s Velocity Management Initiative (Dumond, Eden , and Folkeson, 1995). 50 Data Quality Problems in Army Logistics Some of our...Data Tracking Tech- nique, Holmdel, NJ: AT&T Bell Labs. Berger, Robert D., Edwin Gotwals, and Bobby Chin (1992), “Usage- Based Requirements

  16. Bilateral pallidostriatal necrosis caused by a wasp sting: a clinical and pathological study.

    PubMed

    Gállego, J; Tuñón, T; Soriano, G; Delgado, G; Lacruz, F; Villanueva, J A

    1995-04-01

    A previously healthy man developed an acute encephalopathy with coma after a single wasp sting on his chin. Brain CT showed bilateral pallidostriatal radio-lucencies. He died 72 hours after the sting with no evidence of primary cardiorespiratory failure or allergic reaction. Pathological findings were bilateral pallidostriatal necrosis and diffuse neuronal damage in the frontal, temporal, and parietal cortex. The neurotoxic effect of the poison, together with a hypersensitivity are the most likely explanations for this unusual encephalopathy.

  17. Does Postural Rigidity Decrease during REM Sleep without Atonia in Parkinson Disease?

    PubMed Central

    Arnaldi, Dario; Latimier, Alice; Leu-Semenescu, Smaranda; De Carli, Fabrizio; Vidailhet, Marie; Arnulf, Isabelle

    2016-01-01

    Study Objectives: Rigidity is a muscle hypertonia typical of Parkinson disease (PD), whereas rapid eye movement (REM) sleep behavior disorder (RBD) is characterized by abnormally increased muscle tone during REM sleep (REM sleep without atonia) and enacting dream behaviors. Because movements are not bradykinetic during RBD in patients with PD, we investigated whether the background, wake postural rigidity is attenuated during REM sleep without atonia, in absence of movement. Methods: The amplitude of levator menti (postural muscle) electromyographic activity during relaxed evening wakefulness (considered as reference) and sleep (N2, N3, atonic REM sleep, and quiet REM sleep without atonia) was measured in 20 patients with PD (with and without RBD), 10 patients with idiopathic RBD patients and 10 healthy subjects. Results: The chin tone amplitude progressively decreased from wake to N2, N3, and atonic REM sleep in the four groups, but the highest amplitude was observed in PD patients with RBD during atonic REM sleep. Furthermore, chin muscle tone amplitude did not attenuate from wake to REM sleep without atonia in patients with both PD and RBD but dramatically attenuated (by 40% on average) in patients with idiopathic RBD. Conclusions: The high amplitude of chin muscle tone in PD with RBD (but not in idiopathic RBD) during REM sleep with and without atonia suggests that both PD-related hypertonia and RBD-related enhanced muscle tone coexist during REM sleep, together affecting chin muscle tone. Consequently, some rapid RBD movements likely start against a rigid postural tone. Citation: Arnaldi D, Latimier A, Leu-Semenescu S, De Carli F, Vidailhet M, Arnulf I. Does postural rigidity decrease during REM sleep without atonia in Parkinson disease? J Clin Sleep Med 2016;12(6):839–847. PMID:26857056

  18. Command Wire Sensor Measurements

    DTIC Science & Technology

    2012-09-01

    MEASUREMENTS by Chin Liong Yeo September 2012 Thesis Advisor: David C. Jenn Second Reader : Tri T.Ha THIS PAGE...Second Reader R. Clark Robertson Chair, Department of Electrical and Computer Engineering iv THIS PAGE INTENTIONALLY LEFT BLANK v ABSTRACT...who is my second reader for this thesis. I would also like to express my appreciation to Mr. Robert Broadston for his assistance in helping me set up

  19. Structural Evolution and Kinetics in Cu-Zr Metallic Liquids from Molecular Dynamics Simulations (Postprint)

    DTIC Science & Technology

    2013-10-23

    Finney, Proc. R. Soc. London, Sect. A 319, 479 (1970). 18K. J. Laws, K. F. Shamlaye, K. Wong, B. Gun , and M. Ferry, Metall. Mater. Trans. A 41, 1699...Sci. 56, 379 (2011). 27S. G. Hao, C. Z. Wang, M. J. Kramer, and K. M. Ho, J. Appl. Phys. 107, 053511 (2010). 28Q. K. Li and M. Li, Chin . Sci. Bull. 56

  20. Operate to Know: An Operational and Intelligence for the Operational Level of War

    DTIC Science & Technology

    2014-06-13

    consisted of 24,000 tanks including the T-34 tank, unknown to the Germans before the campaign, which wreaked havoc because of the power of its main gun ...contact, leading with its chin , discovering what was in front of it by physically bumping into the enemy using maneuvering infantry. 1 Dieppe...spotted while they were still in the water. 6 Almost all the landing force elements started taking accurate machine gun fire before they could disembark

  1. Microstructure and Properties of a Refractory NbCrMo0.5Ta0.5TiZr Alloy (Postprint)

    DTIC Science & Technology

    2014-04-01

    phases was con- ucted with the use of an EDS detector attached to the field mission gun SEM. The results are given in Table 2. It is found that he...Microstruc- ture and properties of a refractory TaNbHfZrTi alloy, Unpublished paper, 2011. 10] J.-W. Yeh, S.-K. Chen, S.-J. Lin, J.-Y. Gan, T.-S. Chin , T

  2. South Asian Stability Workshop: A Crisis Simulation Exercise

    DTIC Science & Technology

    2013-10-01

    to  reinforce  the  border.    Sino-­‐Indian  territorial  disputes  over  Arunachal   Pradesh  and  Aksai   Chin  were... guns ).     • Increased  artillery  firepower  (nuclear-­‐capable).     • Slightly  improved  intelligence,  surveillance

  3. Protecting Emergency Responders: Lessons Learned from Terrorist Attacks

    DTIC Science & Technology

    2007-11-02

    terrorist attacks—about one-sixth of the total number of victims. Hun - dreds more were seriously injured. In this light, the terrorist events are...the police have always been gun -toters . . . writing tickets. Terrorist acts with chem/bio and those types of things have always been sec- ondary...out how to put the helmet together.” Chin - straps are not well suited for use by responders who are wearing respirators. Another complaint was that

  4. The Russo-Japanese War, Lessons Not Learned

    DTIC Science & Technology

    2007-11-02

    four infantry battalions, a cavalry squadron, and a gun battery of four guns was sent to guard the rail lines ten miles from the landing site. Local...rise to a height of 300 feet above sea level and overlook the northern approaches of the narrow isthmus and the small town Chin -Chou.15 At low tide the...Additionally, fifteen battery positions were rebuilt to hold ninety field guns (varying in caliber from 56 to 150 millimeters). Ten machineguns were also

  5. North Korea: Terrorism List Removal

    DTIC Science & Technology

    2009-04-15

    Second- 28 Yi Sang-il and Chin Se-ku. Yongbyon nuclear facility can be disabled within...The White House, Roundtable Interview of the President by Foreign Print Media, August 30, 3007. 32 Choe Sang- hun and David E. Sanger, North Korea...2006 through the spring of 2007 to smuggle conventional arms, including machine guns , automatic rifles, and anti-tank rocket launchers, to the

  6. A Remarkable Military Feat: The Hungnam Redeployment, December 1950

    DTIC Science & Technology

    2012-04-01

    of kamikazes and hun - dreds of Shinyo and Renrakutai surface suicide boats against U.S. naval forces at Okinawa for a time rendered ill structured...Thackrey discovered that shipping already in place at Chin - nampo was adequate to requirements. He had extracted 1,800 Army and Navy port personnel...p. 337 note 7. Shepherd left Hun - gnam on 15 December. The following day, after conferring with Joy, he flew to Hawaii, where he reported to Admiral

  7. JPRS Report, Arms Control.

    DTIC Science & Technology

    2007-11-02

    AIDC Chin -Kuo aircraft and Israel’s Lavi fighter, aban- doned two years ago because of soaring costs, flew again for the first time in September this...cordial meeting was Colonel-General Karpati, and Boris Stukalin, ambassador of the Soviet Union to Hun - gary. Pact Generals Depart LD1411212589...will be decreased. This includes artillery guns , howitzers, mortars, and salvo-firing rocket systems. There were real possibilities of agreeing on

  8. Korean Affairs Report.

    DTIC Science & Technology

    2007-11-02

    Korea has fortified all the frontline areas, building underground positions and concealing various weapons. It is even constructing gun positions...also noted that North Korean Frog missiles and self-propelled guns posted just north of the DMZ can hit Seoul directly. North Korean engineer...being major figures in radical student movement. They include U Su- chin , 22, of Songgyung- wan University who is also chairman of the radical student

  9. North Korea: Terrorism List Removal

    DTIC Science & Technology

    2010-01-06

    Chin Se-ku. Yongbyon nuclear facility can be disabled within a year. JongAng Ilbo (internet version), March 13, 2007. 30 Abductions by N. Korea not...3007. 33 Choe Sang- hun and David E. Sanger, North Korea claims U.S. will remove sanctions, International Herald Tribune, September 4, 2007, p. 5...spring of 2007 to smuggle conventional arms, including machine guns , automatic rifles, and anti-tank rocket launchers, to the Tamil Tigers in Sri

  10. North Korea: Back on the Terrorism List

    DTIC Science & Technology

    2010-05-24

    42 Yi Sang-il and Chin Se-ku. Yongbyon nuclear facility can be disabled within a year. JongAng Ilbo (internet version), March 13, 2007. 43...Print Media, August 30, 3007. 46 Choe Sang- hun and David E. Sanger, North Korea claims U.S. will remove sanctions, International Herald Tribune...attempts in late 2006 through the spring of 2007 to smuggle conventional arms, including machine guns , automatic rifles, and anti-tank rocket launchers

  11. JPRS Report. Arms Control.

    DTIC Science & Technology

    2007-11-02

    a North Korean military delegation led by North Korean Minister of People’s Forces O Chin -u conducted negotiations to buy rice from Thailand...possibilities of implementation of the treaty’s protocol on inspection. Military experts from Czechoslovakia, Germany, Hun - gary and the United States...and Hun - gary by 1 July 1991. The troop withdrawal from FRG territory is continuing. We are beginning to withdraw troops from Poland. Thus, further

  12. North Korea: Terrorism List Removal?

    DTIC Science & Technology

    2008-07-10

    and Chin Se-ku. Yongbyon nuclear facility can be disabled within a year. JongAng Ilbo (internet version), March 13, 2007. Korea’s nuclear programs and...the President by Foreign Print Media, August 30, 3007. 30 Choe Sang- hun and David E. Sanger, North Korea claims U.S. will remove sanctions...including machine guns , automatic rifles, and anti-tank rocket launchers, to the Tamil Tigers in Sri Lanka. The Sri Lankan navy intercepted and

  13. Korean Affairs Report

    DTIC Science & Technology

    2007-11-02

    County but also in Kimhwa and Hoeyang Counties. What on earth is the need to build a power station to produce just a few hun - dred thousand kwh at...patriotic act for the country and the nation. A congratulatory speech was made by Kim Tae- chin , an officer of the Korean people’s army, who had been an...resistant, and durable. Therefore, it is very useful in aircraft, rocket parts, special explosive carriers, gun barrels, etc. The fiber is also

  14. Image Understanding Workshop. Proceedings of a Workshop Held in Los Angeles, California on 23-25 February 1987. Volume 1

    DTIC Science & Technology

    1987-02-01

    Jacqueline Le Moigne and Allen M. Waxman, Struc- One final project deals with a model-driven, region- tured Light Patterns for Robot Mobility, CAR-TR...the the topic of many research papers in the area of ma- brightness gradient. To compute the full field, one needs chin viion.Man app aces asedon atchng...International Journal of Robotics system performance must demonstrate robustness in hun - Research 1 pp. 18-64 (Spring 1982). dreds of hours of classified flight

  15. United States Air Force Summer Faculty Research Program (1986). Program Technical Report. Volume 2

    DTIC Science & Technology

    1986-12-01

    Chin Chang H- Optimizdtion Problems 17 Effects of Unchanging Clutter on Dr. Garvin Chastain Peripherally -Precued Covert Attention Shifts 18 Thermo...Adjuvant in the Treatment of Resuscitated (Brooke Formula) Guinea Pigs’ Burn (30, 50 BSA) Shock 148 Analytical Computer Modeling of the Dr. Dennis W...the more formal treatment of Jasperse and Basu. This work will be submitted for publication. Experiments designed to search for the theoretically

  16. The Understanding and Generation of Ellipses in a Natural Language System

    DTIC Science & Technology

    1985-03-12

    Ross, 1Q70) and (Van Oirsouw, 1Q84 ). 6) Reanalyze sentenc:e or produc:e sentenc:e. Understanding: Reanalyzation of the sentence is performed anew...analyzer (Wilensky and Arens, 1Q80) as part of the UC (Unix Consultant) system (Wilensky, Arens and Chin, 1Q84 ) in the event that the PHRAN cannot...Conferenc e on Computational Linguistics, Stanford University, Palo Alto, California, July, 1Q84 . Jackendoff, Ray. Gapping and Related Rules

  17. Metal-Insulator-Metal Diode Process Development for Energy Harvesting Applications

    DTIC Science & Technology

    2010-04-01

    performed using a high -temperature deposition and ion milling process . I-V measurements will be performed on General Order of Operations: 1...Fabricate MIM diodes using one of two processes a. Low-temperature deposition recipes in conjunction with a lift-off process b. High -temperature...Metal-Insulator-Metal Diode Process Development for Energy Harvesting Applications by Matthew Chin, Stephen Kilpatrick, and Dr. Richard

  18. Anopheles Maculatus (Diptera: Culicidae) from the Type Locality of Hong Kong and Two New Species of the Maculatus Complex from the Philippines

    DTIC Science & Technology

    1990-12-01

    cytogenetic studies of natural populations from the Philippines, Thailand, and Malaysia (Green et al. 1985a). In 1986 we worked with C. A. Green to...whether or not populations from all areas of this distribution are conspeci- fit. Populations from Malaysia and Indonesia, for ex- ample, may...the identification of the anopheline larvae of the colony of Hong Kong. Chin. Med. J. 53:259-270. Kinoshita, K. 1906. Uber die Verbreitung der

  19. An Information Security Education Initiative for Engineering and Computer Science

    DTIC Science & Technology

    2007-11-02

    Provost This report was prepared as part of the Naval Postgraduate School Center For Information Systems Security (INFOSEC) Studies and Research (NPS...Released by: DAN BOGER DAVID NETZER¾ý- Acting Dean of Division of Computer and Dean of Research Operations .- ’-rt7 rz Form approved REPORT...and Computer Science Shiu-Kai Chin Cynthia Irvine Department of Electrical and Center for INFOSEC Computer Engineering Studies and Research Syracuse

  20. Concept of Employment for Current Seabasing Capabilities. Integrating Seabasing Capabilities Into Exercises and Experiments

    DTIC Science & Technology

    2010-06-29

    Over the Shore (JLOTS) causeway ferries enable limited at-sea- arrival and assembly, sustainment and reconstitution. Concept of Employment for... shore -based sustainment infrastructure and the time required emplacing it. o Heavy Lift Vertical Take-off and Landing (HLVTOL), including MH- 53E, CH...In January 2010, a massive earthquake measuring 7.3 on the Richter scale hit the impoverished Caribbean island of Haiti causing catastrophic

  1. DNA Lesions in MEDKA (O. Latipes): Development of a Micro-Method for Tissue Analysis Using GC-MS

    DTIC Science & Technology

    1995-08-15

    Fenton reaction . Free Radic Res 1994; 20:345-63. 5. Imlay JA, Chin SM, Linn S. Toxic DNA damage by hydrogen ...peroxide through the Fenton reaction in vivo and in vitro . Science 1988; 240:640-2. 6. Malins DC. Identification of hydroxyl radical-induced lesions in DNA ...on DNA . However, other reactions cannot be ruled out. Difficulties presently exist in precisely defining the proportions of damage inflicted on

  2. DNA Lesions in Medaka (o. latipes): Development of a Micro-Method for Tissue Analysis Using Gas Chromatography-Mass Spectrometry

    DTIC Science & Technology

    1993-07-29

    Imlay, J.A., Chin S.M., and Linn, S. Toxic DNA damage by hydrogen peroxide through the Fenton reaction in vivo and in vitro . 1988. Science 240 (4852...carcinogenesis was obtained when it was shown that 8-OH-Gua was misread in a DNA synthesis system in vitro with E. coli (20). In fact, the presence...represent a growing body of evidence implicating the OOH in DNA damage and carcinogenesis. Formation of the hydroxyl radical The reduction of molecular

  3. JPRS Report, East Asia, Korea: Kulloja, No. 7, July 1989.

    DTIC Science & Technology

    2007-11-02

    Organizations’Basic Duty [Chae Yong -to] 12 Dialogue Is the Basic Form of the Work With People [Kim Ho-chin; article not translated] 15 Economic...position and role the masses of people occupy and play in the development of social history and an attitude and stand toward the masses. In other words...to cultivate the communistic attitude toward labor. Inasmuch as labor administration is in essence work with people , if we, through its improvement

  4. Image splittings in an inhomogeneous universe

    NASA Astrophysics Data System (ADS)

    Wu, Xiangping

    1990-01-01

    In the previous paper [Chin. Phys. Lett. 6 (1989) 233] the amplification, luminosity distances and probabilities for lensing in the case of small optical depth were discussed. As the second part of this work, the present paper will deal with multiple images produced by pointlike lensing objects which are assumed to be the dominant contributors of inhomogeneities in the universe. The expectation values of image separations, the visual magnitude and solid angle of each image will be calculated.

  5. Use of the angularis oris cutaneous flap for repair of a rostral mandibular skin defect in a cat.

    PubMed

    Bradford, M; Degner, D A; Bhandal, J

    2011-01-01

    The angularis oris axial pattern flap is based on the blood supply of the angularis oris artery and vein. While the use of this flap for repair of canine facial wounds is well documented, this technique has not been reported in the cat. This case report presents the reconstruction of a large ventral chin and rostral lip wound with the use of this flap. Complete survival of this flap was observed in this patient.

  6. Myasthenia gravis as a cause of head drop in Parkinson disease.

    PubMed

    Uludag, Irem Fatma; Korucuk, Meltem; Sener, Ufuk; Zorlu, Yasar

    2011-05-01

    Head drop is characterized by marked anterior flexion of the cervical spine. As a result, the affected patient presents with the head tilted forward and the chin resting on the chest. We report a 75-year-old male patient with parkinsonism and head drop caused by isolated myasthenic weakness of the neck extensor muscles. Our case is the second report of isolated head drop as a presenting symptom of myasthenia gravis in a patient with parkinsonism.

  7. The Role of Crk Adaptor Proteins in Breast Tumorigenesis and Bone Metastasis

    DTIC Science & Technology

    2012-09-01

    signature and the basal molecular subtypes found within breast cancer cell lines. Heatmap of the Crk signature in the Neve breast cancer cell line...metastasis to bone. Cancer Cell 2003, 3:537-549. 16. Minn AJ, Gupta GP, Siegel PM, Bos PD , Shu W, Giri DD, Viale A, Olshen AB, Gerald WL, Massague J...prognosis using molecular profiling in estrogen receptor-positive breast cancer treated with tamoxifen. BMC Genomics 2008, 9:239. 27. Neve RM, Chin K

  8. Decreased Expression of the Early Mitotic Gene, CHFR, Contributes to the Acquisition of Breast Cancer Phenotypes

    DTIC Science & Technology

    2008-03-01

    cell line information, including origins and hormone receptor status, has been compiled by Neve et al. (27). Please see Supplementary Table S1 for a...from primary and metastatic sites using selective media. Cancer Res 1993; 53:627–35. 27. Neve RM, Chin K, Fridlyand J, et al. A collection of breast...amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation. Nat Genet. 1998; 20: 189-193. [25] McGhee, EM, Cotter, PD

  9. [Progress of study on the demodex blepharitis].

    PubMed

    Zhang, X Y; Sun, X G

    2016-04-11

    Demodex blepharitis is an infectious ocular disease which is common, but always to be neglected. There were a few related reports about this disease in China. The pathogenic mechanism of demodex blepharitis is not clear at present. Literatures held different ideas about its diagnosis, therapeutic methods and curative effect. This review will summarize the new development of demodex blepharitis in order to provide references for its basic and clinical researches.(Chin J Ophthalmol, 2016, 52: 315-320).

  10. Paraliparis hawaiiensis, a new species of snailfish (Scorpaeniformes: Liparidae) and the first described from the Hawaiian Archipelago.

    PubMed

    Stein, D L; Drazen, J C

    2014-05-01

    Paraliparis hawaiiensis n.sp. is described from the north-western Hawaiian Islands from two specimens collected at 2196 and 3055 m. It differs from other North Pacific Ocean species in its chin pore arrangement, tooth pattern and body proportions. Although liparid specimens have previously been collected from Hawaii, they were undescribed and are now lost. Therefore, this is the first liparid species described from the archipelago. In situ photographs of Hawaiian snailfishes are also shown and discussed here.

  11. Evaluation of the Risk for Work-Related Upper Extremity Musculoskeletal Symptoms in USAF Air Traffic Controllers: A Pilot Feasibility Study

    DTIC Science & Technology

    2011-07-28

    shoulders were level, the range of motion of the shoulder to abduction, cervical flexion, extension and side 15 bending , Phalen’s, Tinel’s, and...restricted if the chin barely (within one finger’s breath) failed to reach the chest and restricted if greater than that. Cervical side bending was...physical examination of both the cervical and iliosacral areas including standing and seated flexion tests, anterior superior iliac spine position, iliac

  12. Medical Management of Radiological Casualties Handbook. First Edition

    DTIC Science & Technology

    1999-12-01

    on the fetus are growth retardation; severe congenital malformations (including errors of metabolism); embryonic, fetal, or neo- 38 natal death; and...gross malfor- mations, occurs when the fetus is irradiated during organogenesis. Radiation-induced malformations of bodily structures other than the...exposed areas of the patient’s face. (1) Chin (2) Neck (3) Back of ears 4. Remove Field Medical Card (FMC) and personal dosimeter 95 a. Cut FMC tie

  13. Linear Lichen Planopilaris of the Face: Case Report and Review

    PubMed Central

    Asz-Sigall, Daniel; González-de-Cossio-Hernández, Ana Cecilia; Rodríguez-Lobato, Erika; Ortega-Springall, María Fernanda; Vega-Memije, María Elisa; Arenas Guzmán, Roberto

    2016-01-01

    We describe the case of a 45-year-old man who presented with a 5-month history of unilateral pruritic linear erythematous papules and atrophy on the chin and mandibular area. Dermoscopy showed areas of cicatricial alopecia with absence of follicular openings, perifollicular erythema and pigment. Lichen planopilaris of the face is a rare variant with only 13 cases reported in the literature. PMID:27843930

  14. Methodological Foundations for Designing Intelligent Computer-Based Training

    DTIC Science & Technology

    1991-09-03

    metacognitive processes (Derry, in press). To this list, we would add that FSM techniques need not be restricted to intelligent tutoring systems. As Chin (1989...systems (pp. 313-333). New York: Springer-Verlag. Derry, S. (in press). Metacognitive models of learning and instructional systems design. In P.H. Winne...15 3.1 Stocks Portfolio Profiler Example .............................. 15 3.1.1 Chart Classes

  15. Near Infrared Pulsed Light for Permanent Hair Reduction in Fitzpatrick Skin Types IV and V

    PubMed Central

    Thacker, Pratik; Kumar, Pramod

    2016-01-01

    Background: Excessive hair on the face is a significant cause for distress amongst women. Permanent hair reduction methods including lasers and pulsed light devices are increasingly being used. Aims: The aim of this study is to evaluate the efficacy and safety of near infrared pulsed light source for permanent hair reduction in women seeking treatment for excessive hair growth on the upper lip and chin. Settings and Design: This was a prospective observational study done at a tertiary care hospital in South India. Materials and Methods: Women above 18 years of age were observed for six sittings of the treatment for excessive hair over the upper lip and chin using a near infrared intense pulsed light device. Efficacy was evaluated by measuring percentage hair reduction using digital photography. Further, efficacy amongst women with polycystic ovarian syndrome (PCOS) was compared with those without PCOS. Side effects were noted. Statistical Analysis Used: Student's unpaired t-test using the software SPSS version 16. Results: Percentage hair reduction at the end of 6 sittings in 24 women for the upper lip and chin was 52.87% and 73.81%, respectively. Out of the 24 women, 12 had PCOS and the difference in hair reduction in these women was statistically insignificant when compared to that observed in those without PCOS. Only two patients experienced side effects in the form of mild pain and discomfort. Conclusions: Intense pulsed light is a safe and efficacious tool for permanent hair reduction over the upper lip and chin, efficacy being similar in patients with or without PCOS. PMID:28163457

  16. Mass Casualty Triage Performance Assessment Tool

    DTIC Science & Technology

    2015-02-01

    substantive information about a trainee’s performance. Unit personnel reviewed the tool for accuracy and functionality . A prototype of medical...government functions ” (Center for Army Lessons Learned, 2006, p.38). During these events, local and state medical personnel are often overwhelmed by...movement. Assessor Feedback: No respiration detected Position the air way using Head-Tilt /Chin-Lift • Kneel at the level of the victims shoulders

  17. ASK Magazine. No. 9

    NASA Technical Reports Server (NTRS)

    Post, Todd (Editor)

    2002-01-01

    Most of this issue is about ACE (Advanced Composition Explorer). We've collected stories by four members of the ACE management team: Don Margolies, the mission manager from Goddard Space Flight Center; Frandsen, science payloads manager from the Caltech Jet Propulsion Laboratory; Mary Chin, project manager in charge of spacecraft development at the Johns Hopkins Applied Physics Laboratory; and Frank Snow, operations and ground systems manager at Goddard.

  18. Vertical Localization of the Malar Prominence

    PubMed Central

    Kaptein, John S.; Markarian, Alexander

    2015-01-01

    Background: During reconstruction or augmentation, it is important to localize the malar complex in a symmetrical and aesthetically pleasing position. Few studies have determined the location of this feature and none related the location to gender, age, or ethnicity. Some of these have attempted to relate the position to the aesthetically pleasing Golden Ratio φ. Methods: We assessed the vertical location of the malar prominence relative to other facial landmarks, determined consistency among individuals, and compared this with values used in artistry. Study population consisted of a convenience sample of 67 patients taken from an otolaryngology practice at a large urban medical center. Coordinates of the malar prominence were referenced to distinct facial landmarks from which the ratio of chin-to-malar prominence to chin-to-eye canthus was determined. Results: Average chin-to-malar prominence distance was 0.793 ± 0.023 (SD) of the chin-to-eye canthus distance. Variability due to the specific image chosen [coefficient of variation (CV) = 1.19%] and combined inter/intrareader variability (CV = 1.71%) validate the methodology. Variability among individuals (CV = 2.84%) indicates population consistency. No difference was found between gender and age groups or between whites and Hispanics. Individuals of other/unknown ethnicities were within the range common to whites and Hispanics. Our population’s value is not different from the value of 0.809 used in artistry, which is based on the Golden Ratio φ. Conclusions: The vertical position of the malar prominence is consistent among individuals, is clinically well-approximated by the value based on the Golden Ratio, and may be useful as a reference for surgical reconstruction or augmentation. PMID:26180712

  19. Facial profile parameters and their relative influence on bilabial prominence and the perceptions of facial profile attractiveness: A novel approach

    PubMed Central

    Denize, Erin Stewart; McDonald, Fraser; Sherriff, Martyn

    2014-01-01

    Objective To evaluate the relative importance of bilabial prominence in relation to other facial profile parameters in a normal population. Methods Profile stimulus images of 38 individuals (28 female and 10 male; ages 19-25 years) were shown to an unrelated group of first-year students (n = 42; ages 18-24 years). The images were individually viewed on a 17-inch monitor. The observers received standardized instructions before viewing. A six-question questionnaire was completed using a Likert-type scale. The responses were analyzed by ordered logistic regression to identify associations between profile characteristics and observer preferences. The Bayesian Information Criterion was used to select variables that explained observer preferences most accurately. Results Nasal, bilabial, and chin prominences; the nasofrontal angle; and lip curls had the greatest effect on overall profile attractiveness perceptions. The lip-chin-throat angle and upper lip curl had the greatest effect on forehead prominence perceptions. The bilabial prominence, nasolabial angle (particularly the lower component), and mentolabial angle had the greatest effect on nasal prominence perceptions. The bilabial prominence, nasolabial angle, chin prominence, and submental length had the greatest effect on lip prominence perceptions. The bilabial prominence, nasolabial angle, mentolabial angle, and submental length had the greatest effect on chin prominence perceptions. Conclusions More prominent lips, within normal limits, may be considered more attractive in the profile view. Profile parameters have a greater influence on their neighboring aesthetic units but indirectly influence related profile parameters, endorsing the importance of achieving an aesthetic balance between relative prominences of all aesthetic units of the facial profile. PMID:25133133

  20. [A patient with hypoaesthesia of the mandible].

    PubMed

    Berrevoets, R A P; Lambregts, P C L A; Aarts, N J M; Vlasveld, L T

    2011-01-01

    In a patient with hypoaesthesia of the central region of the mandible, no oral cause could be found which could explain his complaint. Further examination by a neurologist and a specialist in internal medicine revealed the numb chin syndrome. The syndrome was caused by meningeal localisation of a high-grade B-cell lymphoma stade IV. After intensive chemotherapy and radiotherapy of the skull, the complaints disappeared.

  1. Correction of a mandibular asymmetry after fibula reconstruction using a custom-made polyetheretherketone (PEEK) onlay after implant supported occlusal rehabilitation.

    PubMed

    Berrone, M; Aldiano, C; Pentenero, M; Berrone, S

    2015-10-01

    This study describes an unusual case of mandibular asymmetry after fibula free flap reconstruction in a young man following major facial trauma that was corrected using a custom-made polyetheretherketone prosthesis. There is little information in the literature on the use of alloplasts to correct mandibular asymmetry as interest in 'aesthetic re-modelling' has traditionally focused on nasal, zygomatic and chin regions. This report demonstrates that this technique can be used successfully to address selected cases of mandibular asymmetry.

  2. Biosensors Based on Ultrathin Film Composite Membranes

    DTIC Science & Technology

    1994-01-25

    Lehninger , A . L . Principles of Biochemistry, 1st ed.; Worth Publishers, Inc.: New York, 1982. (33) Ouellette, R. J. Introduction to General Organic...Riley, R. L ; Strathmann, H. Membrane Separation Systems - A Research & Development Needs Assessment, Department of Energy: Washington, D.C., 1990...Boguslavsky, L . L ; Inagaki, T.; Karan, H. L ; Lee, H. S.; Skotheim, T. A .; Okamoto, Y. Anal. Chem. 1991, 63(7), 677-682. (12) Gunasingham, H.; Tan, Chin-H.; Seow

  3. Acute arginine supplementation fails to improve muscle endurance or affect blood pressure responses to resistance training.

    PubMed

    Greer, Beau K; Jones, Brett T

    2011-07-01

    Dietary supplement companies claim that arginine supplements acutely enhance skeletal muscular endurance. The purpose of this study was to determine whether acute arginine α-ketoglutarate supplementation (AAKG) will affect local muscle endurance of the arm and shoulder girdle or the blood pressure (BP) response to anaerobic exercise. Twelve trained college-aged men (22.6 ± 3.8 years) performed 2 trials of exercise separated by at least 1 week. At 4 hours before, and 30 minutes before exercise, a serving of an AAKG supplement (3,700 mg arginine alpha-ketoglutarate per serving) or placebo was administered. Resting BP was assessed pre-exercise after 16 minutes of seated rest, and 5 and 10 minutes postexercise. Three sets each of chin-ups, reverse chin-ups, and push-ups were performed to exhaustion with 3 minutes of rest between each set. Data were analyzed using repeated-measures analysis of variance and paired t-tests. The AAKG supplementation did not improve muscle endurance or significantly affect the BP response to anaerobic work. Subjects performed fewer total chin-ups (23.75 ± 6.38 vs. 25.58 ± 7.18) and total trial repetitions (137.92 ± 28.18 vs. 141.08 ± 28.57) in the supplement trial (p ≤ 0.05). Subjects executed fewer reverse chin-ups (5.83 ± 1.85 vs. 6.75 ± 2.09) during set 2 after receiving the supplement as compared to the placebo (p < 0.05). Because AAKG supplementation may hinder muscular endurance, the use of these supplements before resistance training should be questioned.

  4. Estrogen-dependent estrous behavior in rabbits is antagonized by the antiprogestin RU486.

    PubMed

    González-Mariscal, Gabriela; Gallegos, José Antonio; Rueda Morales, Rafael I; Hoffman, Kurt

    2017-03-01

    Estrogen receptor-alpha (ERα) dimerizes with unliganded progesterone receptor (PR) in target tissues to trigger genomic and non-genomic effects. In ovariectomized rats the antiprogestin RU486 or antisense nucleotides against PR antagonize estradiol-induced sexual receptivity. We determined the relevance of unliganded PR for the expression of estrogen-dependent scent-marking (chinning) and sexual receptivity by injecting RU486 to: a) ovariectomized (ovx) rabbits given estradiol benzoate (EB; 5μg/day); b) intact rabbits. Chinning and lordosis were quantified in ovx animals before (5days; baseline) and during hormonal treatments: EB+RU486 (20mg/day; n=18) or EB+vehicle (n=18). On treatment day 4 LQ (lordosis quotient) increased in both groups, relative to baseline (mean±se): LQ=1±5 (baseline) vs 25±21 (EB+RU486) and 2±6 (baseline) vs 37±29 (EB+vehicle). On day 9 LQ values were: 22±23 (EB+RU486) and 54±39 (EB+vehicle). Chinning increased only in the EB+vehicle group (day 9=55±46 vs baseline=17±20 marks/10min). In intact rabbits one RU486 injection: reduced the LQ from 72±7to 36±8 five hrs later, increased the latency to receive first ejaculation from 45 to 98s, and decreased the number of ejaculations received in the test from 3 to 2 but did not modify mounting latency or chinning. Results support a participation of unliganded PR for the induction (ovx) and maintenance (intact) of rabbit estrous behavior by estrogens.

  5. Effects of Supplemental Citrulline-Malate Ingestion on Blood Lactate, Cardiovascular Dynamics, and Resistance Exercise Performance in Trained Males.

    PubMed

    Wax, Benjamin; Kavazis, Andreas N; Luckett, William

    2016-01-01

    Citrulline-malate (CM) has been proposed to provide an ergogenic effect during resistance exercise; however, there is a paucity of research investigating these claims. Therefore, we investigated the impact that CM supplementation would have on repeated bouts of resistance exercise. Fourteen resistance-trained males participated in a randomized, counterbalanced, double-blind study. Subjects were randomly assigned to placebo (PL) or CM (8 g) and performed three sets each of chin-ups, reverse chin-ups, and push-ups to failure. One week later, subjects ingested the other supplement and performed the same protocol. Blood lactate (BLa), heart rate (HR), and blood pressure (BP) were measured preexercise, with BLa measured a second time immediately following the last set, while HR and BP were measured 5 and 10 min postexercise. Citrulline-malate ingestion significantly increased the amount of repetitions performed for each exercise (chin-ups: PL = 28.4 ± 7.1, CM = 32.2 ± 5.6, p = .003; reverse chin-ups: PL = 26.6 ± 5.6, CM = 32.1 ± 7.1, p = .017; push-ups: PL = 89.1 ± 37.4, CM = 97.7 ± 36.1, p < .001). Blood lactate data indicated a time effect (p < .001), but no treatment differences (p = .935). Systolic BP data did not show differences for time (p = .078) or treatment (p = .119). Diastolic BP data did not show differences for time (p = .069), but indicated treatment differences (p = .014) for subjects ingesting CM. Collectively, these findings suggests that CM increased upper-body resistance performance in trained college-age males.

  6. Myeloid-Derived Suppressor Cells Prevent Type 1 Diabetes in Murine Models

    DTIC Science & Technology

    2010-11-01

    Zhou,* George X. Wang,* Celia M. Divino/ Sofia Casares,§ Shu-Hsia Chen,*’, Wen-Chin Yang/’* and Ping-Ying Pan* Effective immunotherapy for type 1...levels of lymphocyte infiltration in islet and less insulitis compared with that of the control groups. The protective effects of MDSCs might be...9). Accumulating evidence has implicated a potential broad application of MDSCs as a nov- el cell-based immunotherapy within the tields of

  7. Parry-Romberg syndrome in association with contralateral Poland syndrome.

    PubMed

    Dintiman, B J; Shapiro, R S; Hood, A F; Guba, A M

    1990-02-01

    A 35-year-old woman had a 4-year history of skin depression on the right side of both the forehead and chin. A biopsy specimen showed a normal dermis and an absence of subcutaneous tissue. She also had Poland syndrome on the left side of the body, with loss of the sternocostal portion of the greater pectoral muscle. Significant cosmetic improvement was achieved with dermal fat grafts and silicone implants.

  8. Electrocardiograms of Nine Species of Nonhuman Primates Sedated with Ketamine

    DTIC Science & Technology

    1979-06-11

    Premature ventricular contrac- chin monkey (Cebus aPellat. Zentralbl Vcieri directed slightly mnore to the right tions were infrequent; this may be...also tended esthetic agents oin left ventricular function in kes, 2 teP anQTitrasd- to have similar mean values, dogs. Am J Phiol40 232:1-44-1,148. 1977...210-220, 15065. were shorter than was that reported Electrocardiogram and vectorcardiogram of 24. Guonder .JC: Left anterior fascicular by Malhotra et a

  9. Molecular analyses of human induced pluripotent stem cells and embryonic stem cells

    PubMed Central

    Chin, Mark H.; Pellegrini, Matteo; Plath, Kathrin; Lowry, William E.

    2012-01-01

    Recent work from our group and others has argued that human induced pluripotent stem cells (hiPSCs) generated by the introduction of four viruses bearing reprogramming factors differ from human embryonic stem cells (hESCs) at the level of gene expression. Many of the differences seen were common across independent labs and, at least to some extent, are thought to be a result of residual expression of donor cell-specific genes (Chin et al., 2009; Ghosh et al., 2010; Marchetto et al., 2009). Two new reports re-analyze similar expression datasets as those used in Chin et al., (Chin et al., 2009) and come to different conclusions (Newman et al., 2010, Guenther et al., 2010). Here, we compare various approaches to perform gene expression meta-analysis that all support our original conclusions and present new data to demonstrate that polycistronic delivery of the reprogramming factors and extended culture brings hiPSCs transcriptionally much closer to hESCs than older methods. PMID:20682452

  10. Estimation of Delta Wave by Mutual Information of Heartbeat During Sleep

    NASA Astrophysics Data System (ADS)

    Kurihara, Yosuke; Watanabe, Kajiro; Kobayashi, Kazuyuki; Tanaka, Hiroshi

    The quality of sleep is evaluated based on the sleep stages judged by R-K method or the manual of American Academy of Sleep Medicine. The brainwaves, eye movements, and chin EMG of sleeping subjects are used for the judgment. These methods above, however, require some electrodes to be attached to the head and the face to obtain the brainwaves, eye movements, and chin EMG, thus making the measurements troublesome to be held on a daily basis. If non-invasive measurements of brainwaves, eye movements, and chin EMG are feasible, or their equivalent data can be estimated through other bio-signals, the monitoring of the quality of daily sleeps, which influences the health condition, will be easy. In this paper, we discuss the appearance rate of delta wave occurrences, which is deeply related with the depth of sleep, can be estimated based on the average amount of mutual information calculated by pulse wave signals and body movements measured non-invasively by the pneumatic method. As a result, the root mean square error between the appearance rate of delta wave occurrences measured with a polysomnography and the estimated delta pulse was 14.93%.

  11. Craniofacial morphologic parameters in a Persian population: an anthropometric study.

    PubMed

    Amini, Fariborz; Mashayekhi, Ziba; Rahimi, Hajir; Morad, Golnaz

    2014-09-01

    Limited data are available regarding the reference ranges of facial proportions of the Persian population in Iran. This study aimed to establish the reference range of craniofacial anthropometric measurements in an adult Iranian population. On 100 individuals (men = women), aged 18 to 30 years with normal faces and occlusions, 34 linear and 7 angular measurements as well as 24 indices were calculated. The difference of measurements between men and women were evaluated by paired t-test. The data were compared with the norms of North American whites using 1-sample t-test. The subjects belonged to 5 ethnic groups (57% from Fars, 14% from Kord, 11% from Azari, 10% from Gilaki-Mazani, and 2% from Lor). All head measurements were greater in men except for the head index and the head height. The subjects had leptoprosopic faces. The intercanthal width was almost one third of the biocular width and greater than the eye fissure length. Although the nose width of women was significantly smaller, both sexes had leptorrhine noses. The chin height and lower chin height were greater in men. In comparison with North American whites, considerable differences were found regarding head height and width, biocular width, nose height, face height, mouth width, and upper chin height. In conclusion, the reference range of craniofacial anthropometric measurements established for the Iranian population might be efficiently used for esthetic treatments.

  12. [Relationship Between Condylar Size and Transverse Facial Asymmetry in Subject with Condylar Hyperplasia].

    PubMed

    Olate, Sergio; Cantín, Mario; Alister, Juan Pablo; Uribe, Francisca; Navarro, Pablo; Olate, Gabriela; de Moraes, Márcio

    2013-09-01

    Facial asymmetry is a functional and esthetic pathology that can be related to condylar hyperplasia; the aim of this research was to asses the condylar size in the facial asymmetry. Twelve subjects was studies with cone beam computed tomography; the analysis was realized in the software Pax Zenith, Vatech (Korea 2011), using 90 kV and 120 mA and was realized anterior-posterior measurement, superior and inferior measurement and medial-lateral measurement of condylar head and was realized the relations with condylar position with the medial facial line and the position of facial point between superior central incisior, inferior central incisior and chin. The results show that the chin was displaced 6.5 mm from middle line being a hyperplasic condyle with a 2.7 mm more than no hyperplasic condyle. 1 mm of displacement of low central incisor was associated to 2.2 mm of chin displacement. The hyperplasic condyle presented more size and was posicionated 2 mm more lateral than non-hyperplasic condyle. Is conclude that the hyperplasic condyle present a clear influence in the facial transversal asymmetry and in possible to establish a relation between the size of hyperplasic condyle and the facial asymmetry.

  13. Application of genetic algorithms to tuning fuzzy control systems

    NASA Technical Reports Server (NTRS)

    Espy, Todd; Vombrack, Endre; Aldridge, Jack

    1993-01-01

    Real number genetic algorithms (GA) were applied for tuning fuzzy membership functions of three controller applications. The first application is our 'Fuzzy Pong' demonstration, a controller that controls a very responsive system. The performance of the automatically tuned membership functions exceeded that of manually tuned membership functions both when the algorithm started with randomly generated functions and with the best manually-tuned functions. The second GA tunes input membership functions to achieve a specified control surface. The third application is a practical one, a motor controller for a printed circuit manufacturing system. The GA alters the positions and overlaps of the membership functions to accomplish the tuning. The applications, the real number GA approach, the fitness function and population parameters, and the performance improvements achieved are discussed. Directions for further research in tuning input and output membership functions and in tuning fuzzy rules are described.

  14. Understanding the role of histidine in the GHSxG acyltransferase active site motif: Evidence for histidine stabilization of the malonyl-enzyme intermediate

    SciTech Connect

    Poust, Sean; Yoon, Isu; Adams, Paul D.; Katz, Leonard; Petzold, Christopher J.; Keasling, Jay D.

    2014-10-06

    Acyltransferases determine which extender units are incorporated into polyketide and fatty acid products. Thus, the ping-pong acyltransferase mechanism utilizes a serine in a conserved GHSxG motif. However, the role of the conserved histidine in this motif is poorly understood. We observed that a histidine to alanine mutation (H640A) in the GHSxG motif of the malonyl-CoA specific yersiniabactin acyltransferase results in an approximately seven-fold higher hydrolysis rate over the wildtype enzyme, while retaining transacylation activity. We propose two possibilities for the reduction in hydrolysis rate: either H640 structurally stabilizes the protein by hydrogen bonding with a conserved asparagine in the ferredoxin-like subdomain of the protein, or a water-mediated hydrogen bond between H640 and the malonyl moiety stabilizes the malonyl-O-AT ester intermediate.

  15. Lipase-catalyzed synthesis of (S)-naproxen ester prodrug by transesterification in organic solvents.

    PubMed

    Tsai, S W; Tsai, C S; Chang, C S

    1999-06-01

    A lipase-catalyzed enantioselective transesterification process was developed for the synthesis of (S)-naproxen 2-N-morpholinoethyl ester prodrug from racemic 2,2,2-trifluoroethyl naproxen ester in organic solvents. By selecting isooctane and 37 degrees C as the best solvent and temperature, the apparent fits of the initial conversion rates for transesterification and hydrolysis side reaction suggest a ping-pong Bi-Bi enzymatic mechanism with the alcohol as a competitive enzyme inhibitor. Improvements in the initial conversion rate and the productivity for the desired (S)-ester product were obtained after comparing with the result of an enantioselective esterification process. Studies of water content in isooctane and alcohol containing various N,N-dialkylamino groups on the enzyme activity and enantioselectivity, as well as the recovery of (S)-ester product by using extraction, were also reported.

  16. Wide-area ATM networking for large-scale MPPs

    SciTech Connect

    Papadopoulos, P.M.; Geist, G.A. II

    1997-04-01

    This paper presents early experiences with using high-speed ATM interfaces to connect multiple Intel Paragons on both local and wide area networks. The testbed includes the 1024 and 512 node Paragons running the OSF operating system at Oak Ridge National Laboratory and the 1840 node Paragon running the Puma operating system at Sandia National Laboratories. The experimental OC-12 (622 Mbits/sec) interfaces are built by GigaNet and provide a proprietary API for sending AAL-5 encapsulated packets. PVM is used as the massaging infrastructure and significant modifications have been made to use the GigaNet API, operate in the Puma environment, and attain acceptable performance over local networks. These modifications are described along with a discussion of roadblocks to networking MPPs with high-performance interfaces. Our early prototype utilizes approximately 25 percent of an OC-12 circuit and 80 percent of an OC-3 circuit in send plus acknowledgment ping-pong tests.

  17. RF/optical interference design for optical intersatellite links

    NASA Technical Reports Server (NTRS)

    Garlow, Ronald K.; Campanella, S. Joseph

    1990-01-01

    A design approach for the RF/optical link interface for a data relay satellite is described. The flexibility of forward and return links in future data acquisition satellites in handling varying missions and data rates to 1 Gbit/s is considered. Attention is focused on requirements for the NASA Tracking and Data Acquisition System. System components are described including the return link multiplexer, the return link transmultiplexer, the forward link multiplexer, the forward link demultiplexer, and the frontside/backside switch. Ping-pong buffers, which provide rate buffering for each input data stream, are discussed and justification bits, which handle variations due to Doppler shift and local oscillator variation, are considered. The time-division multiplexed streams consist of a unique synchronization word for frame synchronization, and control words associated with each data burst to identify the presence or absence of a justification bit. Redundant data paths are described for both forward and return data streams.

  18. Flies as a source of enteric pathogens in a rural village in Thailand.

    PubMed Central

    Echeverria, P; Harrison, B A; Tirapat, C; McFarland, A

    1983-01-01

    The village of Ban Pong in northeastern Thailand was studied from January through December 1981 to determine the importance of flies as a source of enteric pathogens. The number of flies (predominantly Musca domestica) increased in kitchens and animal pens in the hot dry spring, when the incidence of diarrhea was highest in the village. Enterotoxigenic Escherichia coli, Shigella spp., non-O1 Vibrio cholerae, and Vibrio fluvalis were isolated from fly pools in yards (69%), animal pens (38%), bathrooms (35%), and kitchens (8%). Enterotoxigenic E. coli was isolated from one fly pool in May and from another in June, when the incidence of such infections was highest in the village. Flies often carry and presumably disseminate enteric pathogens in rural Thailand. PMID:6351748

  19. Implications of changing water cycle for the performance and yield characteristics of the multi-purpose Beas Reservoir in India

    NASA Astrophysics Data System (ADS)

    Adeloye, A. J.; Ojha, C. S.; Soundharajan, B.; Remesan, R.

    2013-12-01

    There is considerable change in both the spatial and temporal patterns of monsoon rainfall in India, with implications for water resources availability and security. 'Mitigating the Impacts of Climate Change on India Agriculture' (MICCI) is one of five on-going scientific efforts being sponsored as part of the UK-NERC/India-MOES Changing Water Cycle (South Asia) initiative to further the understanding of the problem and proffer solutions that are robust and effective. This paper focuses on assessing the implications of projected climate change on the yield and performance characteristics of the Pong Reservoir on the Beas River, Himachal Pradesh, India. The Pong serves both hydropower and irrigation needs and is therefore strategic for the socio-economic well-being of the region as well as sustaining the livelihoods of millions of farmers that rely on it for irrigation. Simulated baseline and climate-change perturbed hydro-climate scenarios developed as part of a companion Work Package of MICCI formed the basis of the analysis. For both of these scenarios, reservoir analyses were carried out using the Sequent Peak Algorithm (SPA) and Pong's existing level of releases to derive rule curves for the reservoir. These rule curves then formed the basis of further reservoir behaviour simulations in WEAP and the resulting performance of the reservoir was summarised in terms of reliability, resilience, vulnerability and sustainability. The whole exercise was implemented within a Monte Carlo framework for the benefit of characterising the variability in the assessments. The results show that the rule curves developed using future hydro-climate are significantly changed from the baseline in that higher storages will be required to be maintained in the Pong in the future to achieve reliable performance. As far as the overall performance of the reservoir is concerned, future reliability (both time-based and volume-based) is not significantly different from the baseline, provided

  20. The crystal structure of Pseudomonas putida azoreductase - the active site revisited.

    PubMed

    Gonçalves, Ana Maria D; Mendes, Sónia; de Sanctis, Daniele; Martins, Lígia O; Bento, Isabel

    2013-12-01

    The enzymatic degradation of azo dyes begins with the reduction of the azo bond. In this article, we report the crystal structures of the native azoreductase from Pseudomonas putida MET94 (PpAzoR) (1.60 Å), of PpAzoR in complex with anthraquinone-2-sulfonate (1.50 Å), and of PpAzoR in complex with Reactive Black 5 dye (1.90 Å). These structures reveal the residues and subtle changes that accompany substrate binding and release. Such changes highlight the fine control of access to the catalytic site that is required by the ping-pong mechanism, and in turn the specificity offered by the enzyme towards different substrates. The topology surrounding the active site shows novel features of substrate recognition and binding that help to explain and differentiate the substrate specificity observed among different bacterial azoreductases.

  1. Phosphate monoester hydrolysis by trinuclear alkaline phosphatase; DFT study of transition States and reaction mechanism.

    PubMed

    Chen, Shi-Lu; Liao, Rong-Zhen

    2014-08-04

    Alkaline phosphatase (AP) is a trinuclear metalloenzyme that catalyzes the hydrolysis of a broad range of phosphate monoesters to form inorganic phosphate and alcohol (or phenol). In this paper, by using density functional theory with a model based on a crystal structure, the AP-catalyzed hydrolysis of phosphate monoesters is investigated by calculating two substrates, that is, methyl and p-nitrophenyl phosphates, which represent alkyl and aryl phosphates, respectively. The calculations confirm that the AP reaction employs a "ping-pong" mechanism involving two chemical displacement steps, that is, the displacement of the substrate leaving group by a Ser102 alkoxide and the hydrolysis of the phosphoseryl intermediate by a Zn2-bound hydroxide. Both displacement steps proceed via a concerted associative pathway no matter which substrate is used. Other mechanistic aspects are also studied. Comparison of our calculations with linear free energy relationships experiments shows good agreement.

  2. Recoil Experiments Using a Compressed Air Cannon

    NASA Astrophysics Data System (ADS)

    Taylor, Brett

    2006-12-01

    Ping-Pong vacuum cannons, potato guns, and compressed air cannons are popular and dramatic demonstrations for lecture and lab.1-3 Students enjoy them for the spectacle, but they can also be used effectively to teach physics. Recently we have used a student-built compressed air cannon as a laboratory activity to investigate impulse, conservation of momentum, and kinematics. It is possible to use the cannon, along with the output from an electronic force plate, as the basis for many other experiments in the laboratory. In this paper, we will discuss the recoil experiment done by our students in the lab and also mention a few other possibilities that this apparatus could be used for.

  3. Fighting an old war with a new weapon--silencing transposons by Piwi-interacting RNA.

    PubMed

    Guo, Manhong; Wu, Yuliang

    2013-09-01

    Discovered six decades ago, transposons are known to selfishly multiply within and between chromosomes. Although they may play a creative role in building new functional parts of the genome, transposons usually cause insertional mutagenesis and/or turn nearby genes on or off. To maintain genome integrity, cells use a variety of strategies to defend against the proliferation of transposons. A class of small noncoding RNA, discovered seven years ago and called piRNA, is a new player in the war to silence transposons. piRNA is made via two biogenesis pathways: the primary processing pathway and the ping-pong amplification loop. These pathways are critically involved in transposon RNA degradation, DNA methylation, and histone modification machinery that represses transposons. In this review, we briefly introduce transposon-caused genomic instability and summarize our current understanding of the piRNA pathway, focusing on its key function in transposon silencing.

  4. [Skull fracture and cephalhematoma in a newborn--a case report].

    PubMed

    Zakanj, Zora

    2014-01-01

    Skull fractures and cephalhematoma in newborns belong to the group of birth injuries of the head and neck, accounting for 11.4 to 15% of the total number of birth injuries. We presented a fracture of the parietal bones in a newborn, associated with parietal cephalhematoma. The newborn had transient and mild neurological symptoms: vomiting and changes in muscle tone. Clinical examination confirmed a positive "ping-pong" phenomen, craniogram confirmed the fracture of parietal bones and shown cephalhematoma, as well as ultrasound (US) examinations of the brain showed peri-interventricular bleeding grade II. After the disappearance of all clinical symptoms in a newborn, we observed total bone healing at the end of the second week of life, and good perinatal outcome. Successful recovery from injury contributes to the ability of rapid bone modeling and remodeling, and brain plasticity. Further interdisciplinary monitoring is very important.

  5. Nonribosomal peptide synthesis in animals: the cyclodipeptide synthase of Nematostella.

    PubMed

    Seguin, Jérôme; Moutiez, Mireille; Li, Yan; Belin, Pascal; Lecoq, Alain; Fonvielle, Matthieu; Charbonnier, Jean-Baptiste; Pernodet, Jean-Luc; Gondry, Muriel

    2011-11-23

    Cyclodipeptide synthases (CDPSs) are small enzymes structurally related to class-I aminoacyl-tRNA synthetases (aaRSs). They divert aminoacylated tRNAs from their canonical role in ribosomal protein synthesis, for cyclodipeptide formation. All the CDPSs experimentally characterized to date are bacterial. We show here that a predicted CDPS from the sea anemone Nematostella vectensis is an active CDPS catalyzing the formation of various cyclodipeptides, preferentially containing tryptophan. Our findings demonstrate that eukaryotes encode active CDPSs and suggest that all CDPSs have a similar aminoacyl-tRNA synthetase-like architecture and ping-pong mechanism. They also raise questions about the biological roles of the cyclodipeptides produced in bacteria and eukaryotes.

  6. Understanding the role of histidine in the GHSxG acyltransferase active site motif: Evidence for histidine stabilization of the malonyl-enzyme intermediate

    DOE PAGES

    Poust, Sean; Yoon, Isu; Adams, Paul D.; ...

    2014-10-06

    Acyltransferases determine which extender units are incorporated into polyketide and fatty acid products. Thus, the ping-pong acyltransferase mechanism utilizes a serine in a conserved GHSxG motif. However, the role of the conserved histidine in this motif is poorly understood. We observed that a histidine to alanine mutation (H640A) in the GHSxG motif of the malonyl-CoA specific yersiniabactin acyltransferase results in an approximately seven-fold higher hydrolysis rate over the wildtype enzyme, while retaining transacylation activity. We propose two possibilities for the reduction in hydrolysis rate: either H640 structurally stabilizes the protein by hydrogen bonding with a conserved asparagine in the ferredoxin-likemore » subdomain of the protein, or a water-mediated hydrogen bond between H640 and the malonyl moiety stabilizes the malonyl-O-AT ester intermediate.« less

  7. The life history of Pleurogenoides orientalis (Srivastava, 1934) (Trematoda: Lecithodendriidae).

    PubMed

    Madhavi, R; Dhanumkumari, C; Ratnakumari, T B

    1987-01-01

    The life history of Pleurogenoides orientalis (Srivastava 1934), a lecithodendriid trematode of frogs in India is reported and stages in the life history are described. Natural infections with cercariae, which are virgulate xiphidiocercous type, were found in the prosobranch snail Alocinma travancorica. Metacercarial cysts were found in dragon-fly naiads (Tholymis tillarga and Tramea limbata) and aquatic bugs (Laccotrephes griseus and Ranatra elongata) collected from a stream. Adults occurred in the intestine of the pong frog, Rana cyanophlyctis. Laboratory reared A. travancorica fed with eggs of P. orientalis started shedding cercariae from 30 days post feeding. Development of cercariae into infective metacercariae in dragon-fly naiads took 18 days. Mature flukes were recovered from the intestine of experimentally infected R. cyanophlyctis. The entire life cycle from egg to egg producing adult takes 2 1/2 to 3 months.

  8. Specificity of maltase to maltose in three different directions of reaction: hydrolytic, vanillyl alcohol glucoside and vanillyl alcohol isomaltoside synthesis.

    PubMed

    Dimitrijević, Aleksandra; Veličković, Dušan; Milosavić, Nenad; Bezbradica, Dejan

    2012-01-01

    Vanillyl alcohol glucoside is very attractive molecule due to its very powerful physiological activity. In this article, a detailed kinetic study of transglucosylation of vanillyl alcohol was performed. It was demonstrated that this reaction is very efficient (selectivity factor is 149) and occurred by a ping-pong mechanism with inhibition by glucose acceptor. At low concentration of vanillyl alcohol one additional transglucosylation product was detected. Its structure was determined to be α-isomaltoside of vanillyl alcohol, indicating that vanillyl alcohol glucoside is a product of the first transglucosylation reaction and a substrate for second, so the whole reaction mechanism was proposed. It was demonstrated that the rate of isomaltoside synthesis is two orders of magnitude smaller than glucoside synthesis, and that maltase has interestingly high K(m) value to maltose when vanillyl alcohol glucoside is second transglucosylation substrate.

  9. Modeling of autonomous problem solving process by dynamic construction of task models in multiple tasks environment.

    PubMed

    Ohigashi, Yu; Omori, Takashi

    2006-10-01

    Traditional reinforcement learning (RL) supposes a complex but single task to be solved. When a RL agent faces a task similar to a learned one, the agent must re-learn the task from the beginning because it doesn't reuse the past learned results. This is the problem of quick action learning, which is the foundation of decision making in the real world. In this paper, we suppose agents that can solve a set of tasks similar to each other in a multiple tasks environment, where we encounter various problems one after another, and propose a technique of action learning that can quickly solve similar tasks by reusing previously learned knowledge. In our method, a model-based RL uses a task model constructed by combining primitive local predictors for predicting task and environmental dynamics. To evaluate the proposed method, we performed a computer simulation using a simple ping-pong game with variations.

  10. Structure of Human Phosphopantothenoylcysteine Synthetase at 2.3 Å Resolution

    SciTech Connect

    Manoj, N.; Strauss, E.; Begley, T.P.; Ealick, S.E.

    2010-12-01

    The structure of human phosphopantothenoylcysteine (PPC) synthetase was determined at 2.3 {angstrom} resolution. PPC synthetase is a dimer with identical monomers. Some features of the monomer fold resemble a group of NAD-dependent enzymes, while other features resemble the ribokinase fold. The ATP, phosphopantothenate, and cysteine binding sites were deduced from modeling studies. Highly conserved ATP binding residues include Gly43, Ser61, Gly63, Gly66, Phe230, and Asn258. Highly conserved phosphopantothenate binding residues include Asn59, Ala179, Ala180, and Asp183 from one monomer and Arg55 from the adjacent monomer. The structure predicts a ping pong mechanism with initial formation of an acyladenylate intermediate, followed by release of pyrophosphate and attack by cysteine to form the final products PPC and AMP.

  11. Mn(CO)[sub 5]C(O)-p-C[sub 6]H[sub 5]CH[sub 3]-catalyzed hydrosilane SiH/SiD exchange. Evidence from a kinetics study implicating coordinatively unsaturated manganese silyl intermediates

    SciTech Connect

    Gregg, B.T.; Cutler, A.R. )

    1993-06-01

    The manganese p-toluoyl complex Mn(CO)[sub 5]C(O)-p-CH[sub 3]C[sub 6]H[sub 4] catalyzes SiH/SiD exchange between DSiMe[sub 2]Ph and HSiMe[sub 2]Et at room temperature in C[sub 6]D[sub 6]. The preequilibrium kinetics are consistent with a second-order isotope exchange reaction; plots of initial velocities [nu] against [HSiMe[sub 2]Et] further established saturation kinetics. Lineweaver-Burk plots are in accord with a ping-pong bi-bi mechanism that operates under rapid equilibrium conditions and involves coordinatively unsaturated manganese silyls, (CO)[sub 4]MnSiMe[sub 2/R], as active catalysts. 29 refs., 2 figs.

  12. A biophysically based mathematical model for the catalytic mechanism of glutathione reductase.

    PubMed

    Pannala, Venkat R; Bazil, Jason N; Camara, Amadou K S; Dash, Ranjan K

    2013-12-01

    Glutathione reductase (GR) catalyzes the reduction of oxidized glutathione (GSSG) to reduced glutathione (GSH) using NADPH as the reducing cofactor, and thereby maintains a constant GSH level in the system. GSH scavenges superoxide (O2(*-)) and hydroxyl radicals (OH) nonenzymatically or by serving as an electron donor to several enzymes involved in reactive oxygen species (ROS) detoxification. In either case, GSH oxidizes to GSSG and is subsequently regenerated by the catalytic action of GR. Although the GR kinetic mechanism has been extensively studied under various experimental conditions with variable substrates and products, the catalytic mechanism has not been studied in terms of a mechanistic model that accounts for the effects of the substrates and products on the reaction kinetics. The aim of this study is therefore to develop a comprehensive mathematical model for the catalytic mechanism of GR. We use available experimental data on GR kinetics from various species/sources to develop the mathematical model and estimate the associated model parameters. The model simulations are consistent with the experimental observation that GR operates via both ping-pong and sequential branching mechanisms based on relevant concentrations of its reaction substrate GSSG. Furthermore, we show the observed pH-dependent substrate inhibition of GR activity by GSSG and bimodal behavior of GR activity with pH. The model presents a unique opportunity to understand the effects of products on the kinetics of GR. The model simulations show that under physiological conditions, where both substrates and products are present, the flux distribution depends on the concentrations of both GSSG and NADP(+), with ping-pong flux operating at low levels and sequential flux dominating at higher levels. The kinetic model of GR may serve as a key module for the development of integrated models for ROS-scavenging systems to understand protection of cells under normal and oxidative stress

  13. Aromatic stacking interactions govern catalysis in aryl-alcohol oxidase.

    PubMed

    Ferreira, Patricia; Hernández-Ortega, Aitor; Lucas, Fátima; Carro, Juan; Herguedas, Beatriz; Borrelli, Kenneth W; Guallar, Victor; Martínez, Angel T; Medina, Milagros

    2015-08-01

    Aryl-alcohol oxidase (AAO, EC 1.1.3.7) generates H2 O2 for lignin degradation at the expense of benzylic and other π system-containing primary alcohols, which are oxidized to the corresponding aldehydes. Ligand diffusion studies on Pleurotus eryngii AAO showed a T-shaped stacking interaction between the Tyr92 side chain and the alcohol substrate at the catalytically competent position for concerted hydride and proton transfers. Bi-substrate kinetics analysis revealed that reactions with 3-chloro- or 3-fluorobenzyl alcohols (halogen substituents) proceed via a ping-pong mechanism. However, mono- and dimethoxylated substituents (in 4-methoxybenzyl and 3,4-dimethoxybenzyl alcohols) altered the mechanism and a ternary complex was formed. Electron-withdrawing substituents resulted in lower quantum mechanics stacking energies between aldehyde and the tyrosine side chain, contributing to product release, in agreement with the ping-pong mechanism observed in 3-chloro- and 3-fluorobenzyl alcohol kinetics analysis. In contrast, the higher stacking energies when electron donor substituents are present result in reaction of O2 with the flavin through a ternary complex, in agreement with the kinetics of methoxylated alcohols. The contribution of Tyr92 to the AAO reaction mechanism was investigated by calculation of stacking interaction energies and site-directed mutagenesis. Replacement of Tyr92 by phenylalanine does not alter the AAO kinetic constants (on 4-methoxybenzyl alcohol), most probably because the stacking interaction is still possible. However, introduction of a tryptophan residue at this position strongly reduced the affinity for the substrate (i.e. the pre-steady state Kd and steady-state Km increase by 150-fold and 75-fold, respectively), and therefore the steady-state catalytic efficiency, suggesting that proper stacking is impossible with this bulky residue. The above results confirm the role of Tyr92 in substrate binding, thus governing the kinetic mechanism

  14. Potential of Cerbera odollam as a bio-fungicide for post-harvest pathogen Penicilium digitatum

    NASA Astrophysics Data System (ADS)

    Singh, Harbant; Yin-Chu, Sue; Al-Samarrai, Ghassan; Syarhabil, Muhammad

    2015-05-01

    Postharvest diseases due to fungal infection contribute to economic losses in agriculture industry during storage, transportation or in the market. Penicillium digitatum is one of the common pathogen responsible for the postharvest rot in fruits. This disease is currently being controlled by synthetic fungicides such as Guazatine and Imazalil. However, heavy use of fungicides has resulted in environmental pollution, such as residue in fruit that expose a significant risk to human health. Therefore, there is a strong need to develop alternatives to synthetic fungicide to raise customer confidence. In the current research, different concentrations (500 to 3000 ppm) of ethanol extract of Cerbera odollam or commonly known as Pong-pong were compared with Neem and the controls (Positive control/Guazatine; Negative control/DMSO) for the anti-fungicide activity in PDA media contained in 10 cm diameter Petri dishes, using a modification of Ruch and Worf's method. The toxicity (Lc50) of the C.odollam extract was determined by Brine-shrimp test (BST). The results of the research indicated that crude extraction from C.odollam showed the highest inhibition rate (93%) and smallest colony diameter (0.63 cm) at 3000 ppm in vitro compared with Neem (inhibition rate: 88%; colony diameter: 1.33 cm) and control (Positive control/Guazatine inhibition rate: 79%, colony diameter: 1.9 cm; Negative control/DMSO inhibition rate: 0%, colony diameter: 9.2 cm). C.odollam recorded Lc50 value of 5 µg/ml which is safe but to be used with caution (unsafe level: below 2 µg/ml). The above anti-microbial activity and toxicity value results indicate that C.odollam has a potential of being a future bio-fungicide that could be employed as an alternative to synthetic fungicide.

  15. The noncompetitive inhibitor WW781 senses changes in erythrocyte anion exchanger (AE1) transport site conformation and substrate binding.

    PubMed

    Knauf, P A; Raha, N M; Spinelli, L J

    2000-02-01

    WW781 binds reversibly to red blood cell AE1 and inhibits anion exchange by a two-step mechanism, in which an initial complex (complex 1) is rapidly formed, and then there is a slower equilibration to form a second complex (complex 2) with a lower free energy. According to the ping-pong kinetic model, AE1 can exist in forms with the anion transport site facing either inward or outward, and the transition between these forms is greatly facilitated by binding of a transportable substrate such as Cl(-). Both the rapid initial binding of WW781 and the formation of complex 2 are strongly affected by the conformation of AE1, such that the forms with the transport site facing outward have higher affinity than those with the transport site facing inward. In addition, binding of Cl(-) seems to raise the free energy of complex 2 relative to complex 1, thereby reducing the equilibrium binding affinity, but Cl(-) does not compete directly with WW781. The WW781 binding site, therefore, reveals a part of the AE1 structure that is sensitive to Cl(-) binding and to transport site orientation, in addition to the disulfonic stilbene binding site. The relationship of the inhibitory potency of WW781 under different conditions to the affinities for the different forms of AE1 provides information on the possible asymmetric distributions of unloaded and Cl(-)-loaded transport sites that are consistent with the ping-pong model, and supports the conclusion from flux and nuclear magnetic resonance data that both the unloaded and Cl(-)-loaded sites are very asymmetrically distributed, with far more sites facing the cytoplasm than the outside medium. This asymmetry, together with the ability of WW781 to recruit toward the forms with outward-facing sites, implies that WW781 may be useful for changing the conformation of AE1 in studies of structure-function relationships.

  16. Evaluating the variability in surface water reservoir planning characteristics during climate change impacts assessment

    NASA Astrophysics Data System (ADS)

    Soundharajan, Bankaru-Swamy; Adeloye, Adebayo J.; Remesan, Renji

    2016-07-01

    This study employed a Monte-Carlo simulation approach to characterise the uncertainties in climate change induced variations in storage requirements and performance (reliability (time- and volume-based), resilience, vulnerability and sustainability) of surface water reservoirs. Using a calibrated rainfall-runoff (R-R) model, the baseline runoff scenario was first simulated. The R-R inputs (rainfall and temperature) were then perturbed using plausible delta-changes to produce simulated climate change runoff scenarios. Stochastic models of the runoff were developed and used to generate ensembles of both the current and climate-change-perturbed future runoff scenarios. The resulting runoff ensembles were used to force simulation models of the behaviour of the reservoir to produce 'populations' of required reservoir storage capacity to meet demands, and the performance. Comparing these parameters between the current and the perturbed provided the population of climate change effects which was then analysed to determine the variability in the impacts. The methodology was applied to the Pong reservoir on the Beas River in northern India. The reservoir serves irrigation and hydropower needs and the hydrology of the catchment is highly influenced by Himalayan seasonal snow and glaciers, and Monsoon rainfall, both of which are predicted to change due to climate change. The results show that required reservoir capacity is highly variable with a coefficient of variation (CV) as high as 0.3 as the future climate becomes drier. Of the performance indices, the vulnerability recorded the highest variability (CV up to 0.5) while the volume-based reliability was the least variable. Such variabilities or uncertainties will, no doubt, complicate the development of climate change adaptation measures; however, knowledge of their sheer magnitudes as obtained in this study will help in the formulation of appropriate policy and technical interventions for sustaining and possibly enhancing

  17. Comparison of 2 Interventions for Liquid Aspiration on Pneumonia Incidence A Randomized Trial

    PubMed Central

    Robbins, JoAnne; Gensler, Gary; Hind, Jacqueline; Logemann, Jeri A.; Lindblad, Anne S.; Brand, Diane; Baum, Herbert; Lilienfeld, David; Kosek, Steven; Lundy, Donna; Dikeman, Karen; Kazandjian, Marta; Gramigna, Gary D.; McGarvey-Toler, Susan; Gardner, Patricia J. Miller

    2008-01-01

    Background Aspiration pneumonia is common among frail elderly persons with dysphagia. Although interventions to prevent aspiration in these patients are routinely used in these patients, little is known about the effectiveness of those interventions. Objective To compare the effectiveness of chin-down posture and 2 consistencies (nectar or honey) of thickened liquids on the 3-month cumulative incidence of pneumonia in participants with dementia or Parkinson disease. Design Randomized, controlled, parallel-design trial in which patients were enrolled from 9 June 1998 to 19 September 2005. Setting 47 hospitals and 79 subacute facilities. Patients 515 patients age 50 years or older with dementia or Parkinson disease who aspirated thin liquids (demonstrated videofluoroscopically). Of these, 504 were followed until death or 3 months. Interventions Participants were randomly assigned to drink all liquids in a chin-down posture (n = 259) or to drink nectar-thick (n = 133) or honey-thick (n = 123) liquids in a head-neutral position. Measurements The primary outcome was pneumonia diagnosed by chest radiography or by the presence of 3 respiratory indicators. Results 52 participants had pneumonia, yielding an overall estimated 3-month cumulative incidence of 11%. The 3-month cumulative incidence of pneumonia was 0.098 and 0.116 in the chin-down posture and thickened-liquid groups, respectively (hazard ratio [HR], 0.84 [95% CI, 0.49 to 1.45]; P = 0.53). The 3-month cumulative incidence of pneumonia was 0.084 in the nectar-thick liquid group compared with 0.150 in the honey-thick liquid group (HR, 0.50 [CI, 0.23 to 1.09]; P = 0.083). More patients assigned to thickened liquids than those assigned to the chin-down posture intervention had dehydration (6% vs. 2%), urinary tract infection (6% vs. 3%), and fever (4% vs. 2%). Limitations A no-treatment control group was not included. Follow-up was limited to 3 months. Care providers were not blinded, and differences in cumulative

  18. Proposed helmet PET geometries with add-on detectors for high sensitivity brain imaging.

    PubMed

    Tashima, Hideaki; Yamaya, Taiga

    2016-10-07

    For dedicated brain PET, we can significantly improve sensitivity for the cerebrum region by arranging detectors in a compact hemisphere. The geometrical sensitivity for the top region of the hemisphere is increased compared with conventional cylindrical PET consisting of the same number of detectors. However, the geometrical sensitivity at the center region of the hemisphere is still low because the bottom edge of the field-of-view is open, the same as for the cylindrical PET. In this paper, we proposed a helmet PET with add-on detectors for high sensitivity brain PET imaging for both center and top regions. The key point is the add-on detectors covering some portion of the spherical surface in addition to the hemisphere. As the location of the add-on detectors, we proposed three choices: a chin detector, ear detectors, and a neck detector. For example, the geometrical sensitivity for the region-of-interest at the center was increased by 200% by adding the chin detector which increased the size by 12% of the size of the hemisphere detector. The other add-on detectors gave almost the same increased sensitivity effect as the chin detector did. Compared with standard whole-body-cylindrical PET, the proposed geometries can achieve 2.6 times higher sensitivity for brain region even with less than 1/4 detectors. In addition, we conducted imaging simulations for geometries with a diameter of 250 mm and with high resolution depth-of-interaction detectors. The simulation results showed that the proposed geometries increased image quality, and all of the add-on detectors were equivalently effective. In conclusion, the proposed geometries have high potential for widespread applications in high-sensitivity, high-resolution, and low-cost brain PET imaging.

  19. Long-term three-dimensional stability of mandibular advancement surgery

    PubMed Central

    Franco, Alexandre A.; Cevidanes, Lucia Helena S.; Phillips, Ceib; Rossouw, Paul Emile; Turvey, Timothy A.; Carvalho, Felipe de Assis R.; de Paula, Leonardo K.; Quintão, Cátia Cardoso A.; Almeida, Marco Antonio O.

    2013-01-01

    PURPOSE To evaluate the three-dimensional changes in the position of the condyles, rami, and chin from 1 to 3 years after mandibular advancement surgery. METHOD This prospective observational study used pre and postoperative CBCT scans of 27 subjects with skeletal Class II jaw relationship and normal or deep overbite. An automatic technique of cranial base superimposition was used to assess positional and/or bone remodeling changes that were visually displayed and quantified using 3D color maps. An analysis of covariance with presence of genioplasty, age at the time of surgery, and sex as explanatory variables was used to estimate and test the adjusted mean changes for each region of interest. RESULTS The chin rotated downward and backwards between the 1 and 3 years post-surgery. Changes ≥ 2mm were observed in 17% of the cases. The mandibular condyles presented displacements and/or bone remodeling ≥ 2mm on the anterior surface (21% of the cases on the left and 13% on the right side), superior surfaces (8% on both sides) and lateral poles (17% on the left and 4% on the right side). The posterior borders of the rami exhibited symmetric lateral or rotational displacements in 4% of the cases. CONCLUSION In the hierarchy of surgical stability, mandibular advancement surgery is considered one of the most stable surgical procedures However, between 1 and 3 years post-surgery approximately 20% of the patients had 2-4 mm changes in the horizontal and vertical chin position, and/or changes in condylar position and adaptive bone remodeling. PMID:23769460

  20. Proposed helmet PET geometries with add-on detectors for high sensitivity brain imaging

    NASA Astrophysics Data System (ADS)

    Tashima, Hideaki; Yamaya, Taiga

    2016-10-01

    For dedicated brain PET, we can significantly improve sensitivity for the cerebrum region by arranging detectors in a compact hemisphere. The geometrical sensitivity for the top region of the hemisphere is increased compared with conventional cylindrical PET consisting of the same number of detectors. However, the geometrical sensitivity at the center region of the hemisphere is still low because the bottom edge of the field-of-view is open, the same as for the cylindrical PET. In this paper, we proposed a helmet PET with add-on detectors for high sensitivity brain PET imaging for both center and top regions. The key point is the add-on detectors covering some portion of the spherical surface in addition to the hemisphere. As the location of the add-on detectors, we proposed three choices: a chin detector, ear detectors, and a neck detector. For example, the geometrical sensitivity for the region-of-interest at the center was increased by 200% by adding the chin detector which increased the size by 12% of the size of the hemisphere detector. The other add-on detectors gave almost the same increased sensitivity effect as the chin detector did. Compared with standard whole-body-cylindrical PET, the proposed geometries can achieve 2.6 times higher sensitivity for brain region even with less than 1/4 detectors. In addition, we conducted imaging simulations for geometries with a diameter of 250 mm and with high resolution depth-of-interaction detectors. The simulation results showed that the proposed geometries increased image quality, and all of the add-on detectors were equivalently effective. In conclusion, the proposed geometries have high potential for widespread applications in high-sensitivity, high-resolution, and low-cost brain PET imaging.

  1. Effects of Strengthening Exercises on Swallowing Musculature and Function in Senior Healthy Subjects: a Prospective Effectiveness and Feasibility Study.

    PubMed

    Kraaijenga, S A C; van der Molen, L; Stuiver, M M; Teertstra, H J; Hilgers, F J M; van den Brekel, M W M

    2015-08-01

    Head and neck cancer (HNC) patients may develop dysphagia due to muscle atrophy and fibrosis following chemoradiotherapy. Strengthening of the swallowing muscles through therapeutic exercise is potentially effective for improving swallowing function. We hypothesize that a customized Swallow Exercise Aid (SEA), developed for isometric and isokinetic strengthening exercises (against resistance), can help to functionally strengthen the suprahyoid musculature, which in turn can improve swallowing function. An effectiveness/feasibility study was carried out with ten senior healthy volunteers, who performed exercises 3 times per day for 6 weeks. Exercises included chin tuck against resistance (CTAR), jaw opening against resistance (JOAR), and effortful swallow exercises with the SEA. Multidimensional assessment consisted of measurements of maximum chin tuck and jaw opening strength, maximum tongue strength/endurance, suprahyoid muscle volume, hyoid bone displacement, swallowing transport times, occurrence of laryngeal penetration/aspiration and/or contrast residue, maximum mouth opening, feasibility/compliance (questionnaires), and subjective swallowing complaints (SWAL-QOL). After 6-weeks exercise, mean chin tuck strength, jaw opening strength, anterior tongue strength, suprahyoid muscle volume, and maximum mouth opening significantly increased (p < .05). Feasibility and compliance (median 86 %, range 48-100 %) of the SEA exercises were good. This prospective effectiveness/feasibility study on the effects of CTAR/JOAR isometric and isokinetic strengthening exercises on swallowing musculature and function shows that senior healthy subjects are able to significantly increase swallowing muscle strength and volume after a 6-week training period. These positive results warrant further investigation of effectiveness and feasibility of these SEA exercises in HNC patients with dysphagia.

  2. Eye-rima oris distance and its relation to the vertical dimension of occlusion measured by two methods: Anthropometric study in a sample of Yemeni dental students

    PubMed Central

    Alhajj, Mohammed Nasser; Khalifa, Nadia; Amran, Abdullah

    2016-01-01

    Objective: This study was conducted to evaluate the relationship between the distance measured from the distal outer of the eye to the parting line of the lips and the occlusal vertical dimension (OVD) measured by two methods. Methods: One hundred and fourteen dental students (76 males and 38 females) were recruited for this study with mean age (22.34 ± 1.83) years. The distance from distal canthus of the eye to rima oris (eye-RO) was compared with two different measurements of the OVD (nasal [N] to gnathion [Gn], and subnasal [Sn] to menton [Me]). All distances were measured using modified digital caliper. Results: Pearson correlation coefficient test for correlations and paired samples t-test for differences were used with a significant level of (P < 0.05). There was a positive significant correlation between the eye-RO distance and the two measurements of the OVD. However, this correlation was stronger between eye-RO and the distance from the tip of the nose to the tip of the chin than that between eye-RO and the distance from the septum of the nose to the under of the chin (r = 0.313 with P = 0.0007, r = 0.296 with P = 0.0014), respectively. Conclusion: The distance from the outer canthus of the eye to the parting of the lips seems to be a reliable method in predicting the OVD and should relate to the distance from the tip of the nose to the tip of the chin. PMID:27011736

  3. Cephalometric outcomes of orthognathic surgery in hemifacial microsomia.

    PubMed

    Fattah, Adel Y; Caro, Camila; Khechoyan, David Y; Tompson, Bryan; Forrest, Christopher R; Phillips, John H

    2014-09-01

    Hemifacial microsomia is a hypoplastic disorder of the first and second branchial arches that significantly impacts on the development of the jaws, leading to malocclusion and facial asymmetry. There is little in the literature regarding the application of orthodontic/orthognathic approaches to the correction of these deformities and the stability of the surgical results. To address this, a retrospective chart review of 10 patients with complete orthodontic records and greater than 1 year of follow-up was performed. Posteroanterior cephalograms were assessed by modified Grummons analysis to determine mandibular offset (deviation of the chin point from the skeletal midline) and occlusal cant. These measurements were performed at 3 time points (T1: preoperative, T2: immediate postoperative, T3: follow-up) to elucidate the surgical movement (T2-T1), the postoperative relapse (T3-T2), and the net gain movement (T3-T1). Maxillary movements were quantified, and the occlusal cant was expressed as a ratio between vertical heights of the maxilla at the first molar on each side. One sample t test demonstrated statistically significant surgical movement and net gain. Relapse was statistically insignificant. Repeated-measures analysis of variance demonstrated similar results for chin point position relative to the putative midline. Our results suggest that a combined orthodontic/orthognathic approach at skeletal maturity delivers improved occlusal outcomes in the long term as assessed by chin point deviation and occlusal cant, but secondary surgery rates are higher than those for orthognathic surgery in other patient groups. We advocate limiting surgery to skeletal maturity whenever possible to achieve stable long-term results while limiting morbidity and number of procedures.

  4. Surgical orthodontic correction of mandibular laterognathism

    PubMed Central

    Singh, Harpreet; Srivastava, Dhirendra; Kapoor, Pranav; Sharma, Poonam

    2016-01-01

    This case report describes the successful treatment of a patient with mandibular laterognathism and associated facial asymmetry with combined surgical orthodontic approach. After 7 months of presurgical orthodontic treatment, intraoral vertical ramus osteotomy, and straightening genioplasty were performed as two step surgeries to reposition the deviated mandible and chin, respectively. The total active treatment period was 14 months. After surgical orthodontic treatment, significant improvement in occlusion, masticatory function, and facial appearance was discernible. Posttreatment records at 3 years showed stable results with good occlusion. PMID:27127755

  5. Practical lessons in remote connectivity.

    PubMed Central

    Kouroubali, A.; Starren, J.; Barrows, R. C.; Clayton, P. D.

    1997-01-01

    Community Health Information Networks (CHINs) require the ability to provide computer network connections to many remote sites. During the implementation of the Washington Heights and Inwood Community Health Management Information System (WHICHIS) at the Columbia-Presbyterian Medical Center (CPMC), a number of remote connectivity issues have been encountered. Both technical and non-technical issues were significant during the installation. We developed a work-flow model for this process which may be helpful to any health care institution attempting to provide seamless remote connectivity. This model is presented and implementation lessons are discussed. PMID:9357643

  6. Mini-implants for retraction, intrusion and protraction in a Class II division 1 patient.

    PubMed

    Upadhyay, M; Yadav, S

    2007-09-01

    This case report demonstrates the clinical utility and versatility of mini-implants in carrying out different types of tooth movement in a 14-year-old boy with a 'severe' Class II division 1 malocclusion. Mini-implants were placed for 'en masse' retraction and intrusion of maxillary anterior teeth and for lower molar protraction. More than 11 mm of maxillary incisor retraction was achieved together with 3 mm of intrusion. There was significant reduction in the dentoalveolar protrusion and retraction of the upper lip, which resulted in decreased mentalis strain and improved chin projection. Cephalometric superimposition and panoramic radiographs showed no anchorage loss and good occlusion at the end of treatment.

  7. [Spontaneous loss of permanent teeth in children is never innocent].

    PubMed

    Wit, M A; van der Meij, E H; Hooimeijer, L H; de Vries, T W

    2013-06-01

    A 13-year-old patient spontaneously lost tooth 47. In addition, he had for several weeks experienced numbness of the lower lip and the chin on the right side, fatigue, weakness, loss of appetite, and weight loss. After extensive investigation he seemed to be suffering from a Burkitt lymphoma. Spontaneous loss of permanent teeth in children has an extensive differential diagnosis. Dentists should be familiar with this differential diagnosis as all possible diagnoses are related to serious pathologies. The differential diagnosis includes infectious, metabolic, naplastic, and odontogenic causes. Systematic history taking, physical examination and laboratory investigations will lead to a proper diagnosis.

  8. Issues in impedance selection and input devices for multijoint powered orthotics.

    PubMed

    Lemay, M A; Hogan, N; van Dorsten, J W

    1998-03-01

    We investigated the applicability of impedance controllers to robotic orthoses for arm movements. We had tetraplegics turn a crank using their paralyzed arm propelled by a planar robot manipulandum. The robot was under impedance control, and chin motion served as command source. Stiffness varied between 50, 100, or 200 N/m and damping varied between 5 or 15 N/m/s. Results indicated that a low stiffness and high viscosity provided better directional control of the tangential force exerted on the crank.

  9. Purification of Transketolase from Human Erythrocytes. 1. Using Solvent Denaturation as the Initial Step.

    DTIC Science & Technology

    1980-07-01

    and fructose -6-phosphate (F-6-P) (Figure 1); this would result in the accumulation of more S-7-P or GAP. The use of solvent denaturation as the initial...DE FLORA, and H. :IANGIAROTTI. A direct interconversion: d- fructose 6-phosphate -sedoheptulose 7-phosphate and d-xylulose 5-phosahate catalyzed by the...purification and properties. Helv Chin Acta 54: 2658- 2668, 1971 26. 011, S.H., H.E. GA\\THER, and W.G. HOEKSTRA. Selenium as a compo- nent of

  10. Sensitivity of ultracold-atom scattering experiments to variation of the fine-structure constant

    SciTech Connect

    Borschevsky, A.; Beloy, K.; Flambaum, V. V.; Schwerdtfeger, P.

    2011-05-15

    We present numerical calculations for cesium and mercury to estimate the sensitivity of the scattering length to the variation of the fine-structure constant {alpha}. The method used follows the ideas of Chin and Flambaum [Phys. Rev. Lett. 96, 230801 (2006)], where the sensitivity to the variation of the electron-to-proton mass ratio {beta} was considered. We demonstrate that for heavy systems, the sensitivity to the variation of {alpha} is of the same order of magnitude as to the variation of {beta}. Near narrow Feshbach resonances, the enhancement of the sensitivity may exceed nine orders of magnitude.

  11. Management of congenital muscular torticollis in a child: a case report and review.

    PubMed

    Ta, Jennifer H; Krishnan, Miguel

    2012-11-01

    Congenital muscular torticollis is a condition in which the sternocleidomastoid muscle is shortened on the involved side, leading to an ipsilateral tilt of the head and a contralateral rotation of the face and chin. Most of these patients present in infancy and are successfully treated with physical therapy. Occasionally, patients present in childhood at which time conservative management is rarely successful. Here we present a child with torticollis who was successfully managed with a unipolar release of the sternocleidomastoid. We then review the epidemiology, proposed etiologies, and various treatment options for torticollis and their rates of success.

  12. Pygmoid Australomelanesian Homo sapiens skeletal remains from Liang Bua, Flores: population affinities and pathological abnormalities.

    PubMed

    Jacob, T; Indriati, E; Soejono, R P; Hsü, K; Frayer, D W; Eckhardt, R B; Kuperavage, A J; Thorne, A; Henneberg, M

    2006-09-05

    Liang Bua 1 (LB1) exhibits marked craniofacial and postcranial asymmetries and other indicators of abnormal growth and development. Anomalies aside, 140 cranial features place LB1 within modern human ranges of variation, resembling Australomelanesian populations. Mandibular and dental features of LB1 and LB6/1 either show no substantial deviation from modern Homo sapiens or share features (receding chins and rotated premolars) with Rampasasa pygmies now living near Liang Bua Cave. We propose that LB1 is drawn from an earlier pygmy H. sapiens population but individually shows signs of a developmental abnormality, including microcephaly. Additional mandibular and postcranial remains from the site share small body size but not microcephaly.

  13. Post-Crazing Stress Analysis of Glass-Epoxy Laminates.

    DTIC Science & Technology

    1979-05-01

    PERFORMING ORG . RyORT NUMBER TTU-ESM-79-i 7. AUTHOR(s) S. CONTRACT OR GRANT NUMBER(.) Dallas G. Smith and Ju-Chin Huang DAAK40-78-C-0165 9. PERFORMING...COOES / X 4JH4L~rEP x y 3 ALPHIA iArA INa .?C4C FCR4A i(//l Xp40MGENE-ArAff) 10~ COOFS L / X 40H NO 0E 39JUNDA9Y CONDITION Cl1OES I Lk~ 4)HMU;4iER X

  14. Three-dimensional assessment of mandibular advancement 1 year after surgery

    PubMed Central

    de Assis Ribeiro Carvalho, Felipe; Cevidanes, Lucia Helena Soares; Motta, Alexandre Trindade Simões da; de Oliveira Almeida, Marco Antonio; Phillips, Ceib

    2010-01-01

    Introduction This prospective observational study evaluated changes in the 3-dimensional position and remodeling of the mandibular rami, condyles, and chin at splint removal and 1 year after mandibular advancement surgery. Methods Presurgery, splint removal (4–6 weeks postsurgery), and 1-year postsurgery cone-beam computed tomography scans of 27 subjects were used. Superimposition on the cranial base was used to assess positional or remodeling changes in the anatomic regions of interest. Surface distance displacements were visually displayed and quantified by 3-dimensional color maps. A 1-sample t test was used to assess the average postsurgical changes of each region of interest. The level of significance was set at 0.05. Results After antero-inferior chin displacement with surgery (mean, 6.81 ± 3.2 mm at splint removal), the average 1-year post-surgery displacement was not statistically significant (P = 0.44). Postsurgical adaptations greater than 2 mm were observed in 48% of the patients: 16% with an additional anterior-inferior displacement of the chin of 2 to 4 mm, and 4% with ≥4 mm; 20% had postero-superior movement of 2 to 4 mm, and 8% had postero-superior movement of ≥4 mm. The condyles tended to move, on average, ≤2 mm supero-posteriorly with surgery, and this small positional displacement was maintained 1 year postsurgery (right condyle, P = 0.58; left, P = 0.88). The rami exhibited outward (lateral) movements with surgery, with greater displacement of the inferior part of the rami (≥2 mm in 65% of the subjects). This torque of the ramus with surgery was stable 1 year postsurgery. Conclusions Three-dimensional assessment of skeletal changes with mandibular advancement surgery shows that nearly half of the patients have >2 mm change in chin position from splint removal to the 1-year follow-up, with approximately equal chances of anterior and posterior movement. Torque of the rami usually occurs with mandibular advancement surgery. PMID:20381760

  15. Suppression of BRCA2 by Mutant Mitochondrial DNA in Prostate Cancer

    DTIC Science & Technology

    2014-07-01

    Lai3, Kai -Hsiung Chang4,Kaijie Wu5, Shu-Fen Tseng6, Ladan Fazli7, Martin Gleave7,Guanghua Xiao8, Leah Gandee2, Nima Sharifi4, Loredana Moro9,Tzong...2003; 11(5):1177-1188. 18. Gao D, Inuzuka H, Tseng A, Chin RY, Toker A and Wei W. Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2... Wei W. Akt finds its new path to regulate cell cycle through modulating Skp2 activity and its destruction by APC/Cdh1. Cell Div. 2009; 4:11. 32. Xie

  16. Comparing Global Influence: China’s and U.S. Diplomacy, Foreign Aid, Trade, and Investment in the Developing World

    DTIC Science & Technology

    2008-08-15

    actual story may not be in who has the most guns , largest aid budget, or whose companies are trading with and investing the most in developing...January 2006 and a China- CRS-40 104 Chua Chin Hon, “China Sets Out to Build on Ties with Africa,” Straits Times, January 13, 2006; and “Action Plan...major aid donor to drop restrictions). The U.S. government had imposed restrictions on foreign assistance to Cambodia following Prime Minister Hun

  17. North Korea: Terrorism List Removal

    DTIC Science & Technology

    2009-07-01

    version), August 14, 2007. 28 See http://www.state.gov/s/ct/rls/crt/2006/82736.htm at p. 147. 29 Yi Sang-il and Chin Se-ku. Yongbyon nuclear facility...Department spokesman. 32 The White House, Roundtable Interview of the President by Foreign Print Media, August 30, 3007. 33 Choe Sang- hun and David E...several North Korean attempts in late 2006 through the spring of 2007 to smuggle conventional arms, including machine guns , automatic rifles, and anti

  18. Korean Affairs Report

    DTIC Science & Technology

    2007-11-02

    fierce whirlwind of struggle, and had the military turned the muzzle of their guns against Chongwadae by siding with the masses. [Kim] You are right...Korea 283.40 3. Japan 279.55 4. Hong Kong 189.25 Individual Competition Name Points 1. Yang Yueshan (China) 58.10 2. Pak Chong- hun (Korea) 57.35...for exports amounting to $500 million. In addition, Trade-Industry Minister Kim Chin -ho is scheduled to visit Japan next week as a presidential

  19. Korean Affairs Report.

    DTIC Science & Technology

    2007-11-02

    people with guns and bayonets or deceiving them. Originally, in trying to host the Asian Games and the Olympic Games in South Korea, the puppet...our opposition." Assemblyman Yi Yong- hun : »Although I am of the opinion that I should return to law and spend the rest of my life there, I also need...tomorrow, No Yong-hui, a professor of public admin- istration at Seoul National University, will deliver a paper on the local council. Prof. Kim Nam- chin

  20. North Korea: Terrorism List Removal

    DTIC Science & Technology

    2008-11-06

    ct/rls/crt/2006/82736.htm] at p. 147. 28 Yi Sang-il and Chin Se-ku. Yongbyon nuclear facility can be disabled within a year. JongAng Ilbo (internet...Interview of the President by Foreign Print Media, August 30, 3007. 32 Choe Sang- hun and David E. Sanger, North Korea claims U.S. will remove sanctions...smuggle conventional arms, including machine guns , automatic rifles, and anti-tank rocket launchers, to the Tamil Tigers in Sri Lanka. The Sri Lankan

  1. North Korea: Terrorism List Removal?

    DTIC Science & Technology

    2007-12-11

    internet version), August 14, 2007. 22 See [http://www.state.gov/s/ct/rls/crt/2006/82736.htm] at p. 147. 23 Yi Sang-il and Chin Se-ku. Yongbyon...Department spokesman. 26 The White House, Roundtable Interview of the President by Foreign Print Media, August 30, 3007. 27 Choe Sang- hun and David E...conventional arms, including machine guns , automatic rifles, and anti-tank rocket launchers, to the Tamil Tigers in Sri Lanka. The Sri Lankan navy

  2. North Korea: Back on the Terrorism List?

    DTIC Science & Technology

    2010-06-29

    2007. 46 See http://www.state.gov/s/ct/rls/crt/2006/82736.htm at p. 147. 47 Yi Sang-il and Chin Se-ku. Yongbyon nuclear facility can be disabled within...Choe Sang- hun and David E. Sanger, North Korea claims U.S. will remove sanctions, International Herald Tribune, September 4, 2007, p. 5. 52 Japanese...several North Korean attempts in late 2006 through the spring of 2007 to smuggle conventional arms, including machine guns , automatic rifles, and anti

  3. Air-to-Ground Target Acquisition Source Book: A Review of the Literature

    DTIC Science & Technology

    1974-09-30

    identification of targets. Sun ;tianle refern to the direction of thc un In relation to thu aIr- craft is track. ’lle effect of Hun angle on target rr-cogniLion...whether the observed contrast is groater than the contrast threshold using the equation CHIN " e-Ov where v is the visibility range. The threshold value...constructed by Jacqueline I. Gordon can be used to quickly determine (a) the beam transmittance for a horizontal path of sight from the attenuation

  4. [Lymphatic system of the tongue and its role in glositis of odontogenic origin].

    PubMed

    Chkhikvishvili, M Dzh

    2005-02-01

    In aged persons reduction of diameter of tongue lymphatic capillaries precedes thinning of the Kaarl net. In the process of tongue inflammation, lymphogenic way of inclusion in 6|6 and 8|8 teeth lower area should be stuck out with existence of alleged "Integration Centers". Lymphatic knots and lymphatic ducts are in prevailed placed in corresponding tissues of lower-chin and lower teeth. Lymphatic-muscular system and its anatomical links and age-related changeability raise the special interest during odontogenic infections with tongue inflammation.

  5. Theoretical analysis of optical coupling properties of the waveguide grating with novel rectangular structure

    NASA Astrophysics Data System (ADS)

    Yang, Yong-Bin; Wang, Yu-Rong; Yu, Xiao-Qiang

    2007-07-01

    For the waveguide grating photocoupler with novel structure [Yu XQ, Zhang X, Wong KS, Xu GB, Xu XG, Ren Y, et al. A fabrication of coupling grating in the polymeric waveguide by using two-photon initiated photopolymerization. Mater Lett 2004;58:3879-83. [1]; Yu XQ, Zhang X, Xu GB, Zhao HP, He W, Shao ZS, et al. Fabrication of grating waveguide and coupling grating using two-photon initiated photopolymerization. Chem J Chin Univ 2004;25(10):1931-3 (in Chinese). [2

  6. A case of mental nerve paresthesia due to dynamic compression of alveolar inferior nerve along an elongated styloid process.

    PubMed

    Gooris, Peter J J; Zijlmans, Jan C M; Bergsma, J Eelco; Mensink, Gertjan

    2014-07-01

    Spontaneous paresthesia of the mental nerve is considered an ominous clinical sign. Mental nerve paresthesia has also been referred to as numb chin syndrome. Several potentially different factors have been investigated for their role in interfering with the inferior alveolar nerve (IAN) and causing mental nerve neuropathy. In the present case, the patient had an elongated calcified styloid process that we hypothesized had caused IAN irritation during mandibular movement. This eventually resulted in progressive loss of sensation in the mental nerve region. To our knowledge, this dynamic irritation, with complete recovery after resection of the styloid process, has not been previously reported.

  7. Cryptanalysis of Controlled Mutual Quantum Entity Authentication Using Entanglement Swapping

    NASA Astrophysics Data System (ADS)

    Gao, Gan; Wang, Yue

    2017-01-01

    By using GHZ-like states and entanglement swapping, Kang et al. [Chin. Phys. B 24 (2015) 090306] proposed a controlled mutual quantum entity authentication protocol. We find that the proposed protocol is not secure, that is, the center, Charlie can eavesdrop the secret keys shared between Alice and Bob without being detected. Supported by the 2014-year Program for Excellent Youth Talents in University of Anhui Province and the Talent Scientific Research Fundation of Tongling University under Grant No. 2015tlxyrc01 and the Program for Academic Leader Reserve Candidates in Tongling University under Grant No. 2014tlxyxs30

  8. Achievements in Chinese Traditional Medical Treatment of Schistosomiasis and Malaria - Communist China

    DTIC Science & Technology

    2007-11-02

    Afcademia Sinica, the resalts of syst^J.^^fp^ention and show that pumpkin seed taken orally " effective^in the^pr ev n treateent of exper^entaa sc "jg...34™^ S d^^re was 95-77^ three grams of pumpkan seed orally daily ior o J parasites, it raised the ^f ^^f^^^Äics Departoent of the fell and the...the drug from three to seven days. , „, ,. ,_. * (c) Ch’ien-chin-tzu and Hsiao-shui Pills: Ch’xen chxn-tzu is the seed of a plant of the family

  9. Dermatoses of the neck affecting violin and viola players ("fiddler's neck", and contact dermatitis).

    PubMed

    Tennstedt, D; Cromphaut, P; Dooms-Goossens, A; Lachapelle, J M

    1979-01-01

    Skin lesions occurring on the neck of violin or viola players are described, in the light of two personal observations. The lesions can be divided into two types: 1. Lesions described as "fiddler's neck", i.e. an area of erythematous, sometimes pigmented or scaly lichenification on the left side of the neck, just below the angle of the jaw, where the chin rest of the instrument is in contact with the skin. Histopathologic features of the lesions are described. 2. Allergic contact dermatitis to wooden or metallic parts of the violin. The recent literature is reviewed.

  10. The Lunar Orbiter Laser Altimeter Investigation on the Lunar Reconnaissance Orbiter Mission

    NASA Astrophysics Data System (ADS)

    Smith, David E.; Zuber, Maria T.; Jackson, Glenn B.; Cavanaugh, John F.; Neumann, Gregory A.; Riris, Haris; Sun, Xiaoli; Zellar, Ronald S.; Coltharp, Craig; Connelly, Joseph; Katz, Richard B.; Kleyner, Igor; Liiva, Peter; Matuszeski, Adam; Mazarico, Erwan M.; McGarry, Jan F.; Novo-Gradac, Anne-Marie; Ott, Melanie N.; Peters, Carlton; Ramos-Izquierdo, Luis A.; Ramsey, Lawrence; Rowlands, David D.; Schmidt, Stephen; Scott, V. Stanley; Shaw, George B.; Smith, James C.; Swinski, Joseph-Paul; Torrence, Mark H.; Unger, Glenn; Yu, Anthony W.; Zagwodzki, Thomas W.

    2010-01-01

    The Lunar Orbiter Laser Altimeter (LOLA) is an instrument on the payload of NASA’s Lunar Reconnaissance Orbiter spacecraft (LRO) (Chin et al., in Space Sci. Rev. 129:391-419, 2007). The instrument is designed to measure the shape of the Moon by measuring precisely the range from the spacecraft to the lunar surface, and incorporating precision orbit determination of LRO, referencing surface ranges to the Moon’s center of mass. LOLA has 5 beams and operates at 28 Hz, with a nominal accuracy of 10 cm. Its primary objective is to produce a global geodetic grid for the Moon to which all other observations can be precisely referenced.

  11. Early neutron stars and quark matter

    NASA Astrophysics Data System (ADS)

    Li, You-Chen; Kong, Xiao-Jun; Wei, Cheng-Wen; Ge, Yun-Zhao

    1988-03-01

    The existence of quark matter (QM) in hot early neutron stars is considered theoretically, using the method of Baym and Chin (1976) to calculate the pressure and density at the phase transition between neutron and quark matter for various temperatures. The results are presented in tables and graphs and discussed in detail. It is found that QM cores can exist whenever the temperature exceeds 10 to the 10th K, and that their radii increase with decreasing QM bag constant. The total energy emitted by a star during cooling is estimated as 10 to the 53rd erg, assuming conservation of baryon number.

  12. A Comparison between the Stabilization Method and the Post-stabilization Method

    NASA Astrophysics Data System (ADS)

    Zhu, Jun-fang; Wu, Xin

    2007-01-01

    A detailed discussion on Baumgarte's stabilization method and Chin's post-stabilization method is carried out together with a numerical comparison. The numerical accuracy can be increased and the numerical stability can be improved by combining the classical numerical method with either of the two stabilization methods. Assuming optimal stabilizing parameter the accuracy is not the same in the two methods and it is not certain which one is the more accurate. While noting the reasons underlying the post-stabilization scheme, it is inadvisable, when applying the latter, to use step lengths greater than are recommended by the original classical integrator with no stabilization.

  13. Application of a new non-linear least squares velocity curve analysis technique for spectroscopic binary stars

    NASA Astrophysics Data System (ADS)

    Karami, K.; Mohebi, R.; Soltanzadeh, M. M.

    2008-11-01

    Using measured radial velocity data of nine double lined spectroscopic binary systems NSV 223, AB And, V2082 Cyg, HS Her, V918 Her, BV Dra, BW Dra, V2357 Oph, and YZ Cas, we find corresponding orbital and spectroscopic elements via the method introduced by Karami and Mohebi (Chin. J. Astron. Astrophys. 7:558, 2007a) and Karami and Teimoorinia (Astrophys. Space Sci. 311:435, 2007). Our numerical results are in good agreement with those obtained by others using more traditional methods.

  14. Comparison of eye movements over faces in photographic positives and negatives.

    PubMed

    Luria, Saul M; Strauss, Mark S

    2013-01-01

    Eye movements were recorded while subjects viewed ordinary portraits and photographic negatives of those portraits. Under both conditions they first studied sixteen portraits and then tried to decide which of forty-eight portraits they had just seen. They made more errors of recognition while viewing negatives, and their fixation patterns were significantly altered: there was a decrease in the percentage of fixations directed to the eyes, nose, and mouth, and an increase for such details as the ears, cheeks, chin, cap, and necktie. There was also a decrease in the ratio of fixations to the most fixated detail compared to the least fixated detail.

  15. Epithelial and Fibrous Hyperplasia: An Oral Manifestation of Tuberous Sclerosis Complex. A Case Study.

    PubMed

    Mbibi, Sandra U; Segelnick, Stuart L; Weinberg, Mea A

    2015-01-01

    The authors present a case study of a 13-year-old female with a past medical history of tuberous sclerosis complex (TSC), an autosomal dominant disorder. It usually presents with a triad of epilepsy, mental deficiency and facial angiofibromas that are often distributed around the nose, cheek and chin, and are frequently shaped like butterfly wings. In addition, oral manifestations include gingival enlargement and developmental enamel pitting on the facial aspect of the anterior permanent dentition in 50% to 100% of patients. The patient's chief complaint was gingival enlargement and gingival bleeding. The histology of the excised gingival tissue revealed epithelial and fibrous hyperplasia, consistent with TSC.

  16. A Trade Study of Thermosphere Empirical Neutral Density Models

    DTIC Science & Technology

    2014-08-01

    OCP 8725 John J. Kingman Rd, Suite 0944 Ft Belvoir, VA 22060-6218 1 cy AFRL /RVIL Kirtland AFB, NM 87117-5776 2 cys Official Record Copy AFRL ... AFRL -RV-PS- TR-2016-0008 AFRL -RV-PS- TR-2016-0008 A TRADE STUDY OF THERMOSPHERE EMPIRICAL NEUTRAL DENSITY MODELS Chin S. Lin, et al. 1 August...Ave SE AIR FORCE MATERIEL COMMAND KIRTLAND AIR FORCE BASE, NM 87117-5776 DTIC COPY NOTICE AND SIGNATURE PAGE Using Government drawings

  17. PubMed Central

    ALDIANO, C.; PENTENERO, M.; BERRONE, S.

    2015-01-01

    SUMMARY This study describes an unusual case of mandibular asymmetry after fibula free flap reconstruction in a young man following major facial trauma that was corrected using a custom-made polyetheretherketone prosthesis. There is little information in the literature on the use of alloplasts to correct mandibular asymmetry as interest in 'aesthetic re-modelling' has traditionally focused on nasal, zygomatic and chin regions. This report demonstrates that this technique can be used successfully to address selected cases of mandibular asymmetry. PMID:26824216

  18. Mathematical Modeling of Physical and Cognitive Performance Decrement from Mechanical and Inhalation Insults

    DTIC Science & Technology

    2009-12-01

    that segregates load paths within the cervical spine. Static air bag deployment tests were carried out with the dummy positioned in the NHTSA-1 (chin on...Negative Fx – neck rearward  wrt head Positive My ‐ Flexion   Time (msec) Sh ea r ( N ) M om ent, (N ‐m ) Negative Fx – neck rearward  wrt head Negative

  19. Cryptanalysis of quantum broadcast communication and authentication protocol with a one-time pad

    NASA Astrophysics Data System (ADS)

    Cao, Ya; Gao, Fei

    2016-11-01

    Chang et al. [Chin. Phys. B 23 010305 (2014)] have proposed a quantum broadcast communication and authentication protocol. However, we find that an intercept-resend attack can be preformed successfully by a potential eavesdropper, who will be able to destroy the authentication function. Afterwards, he or she can acquire the secret transmitted message or even modify it while escaping detection, by implementing an efficient man-in-the-middle attack. Furthermore, we show a simple scheme to defend this attack, that is, applying non-reusable identity strings. Project supported by the National Natural Science Foundation of China (Grant Nos. 61272057 and 61170270).

  20. Visual decodification of some facial expressions through microimitation.

    PubMed

    Ruggieri, V; Fiorenza, M; Sabatini, N

    1986-04-01

    We examined the level of muscular tension of mentalis muscle of 36 students in graphic design at rest and during the presentation of three slides reproducing facial expressions. Analysis showed an increase in the myographic level of mentalis muscle from the third second of measurement onwards after the presentation of the slide in which contraction of the chin was involved. We interpret this result by hypothesizing that the decodification of some facial expressions is realized through a microreproduction of the stimulus from the decodifying subject.

  1. A Collation of United States Air Force Anthropometry

    DTIC Science & Technology

    1986-01-14

    ABDOMINAL EXTENSIO CIRCUFERENCE OVER FOUNl TON AMLENT STANDING - see also Abdominal Extension Circumference, Standing; and Waist Circumference at Natural...15.1 ANTERIOR NECK LENGTH - see also Posterior Neck Length Subject stands erect, head in the Frankfort Plane - the surface distance from chin- neck ...posterior aspect of the skull which can be palpated among the neck muscles. USAF.MEN 10.43 .48 9.4 9.6 10.4 11.2 11.6 n = 1236 26.50 1.21 23.9 24.5 26.5

  2. Hypersonic airbreathing missile concepts under study at NASA Langley Research Center

    NASA Technical Reports Server (NTRS)

    Hunt, J. L.; Johnston, P. J.; Cubbage, J. M.; Dillon, J. L.; Richie, C. B.; Marcum, D. C., Jr.; Carlson, C. H.

    1982-01-01

    The design and performance of several tactical and strategic hypersonic airbreathing missile concepts under study at the NASA Langley Research Center are discussed from an evolutionary perspective. A mid- and chin inlet missile design, constrained to the Navy's vertical box launcher, was investigated; a performance comparison is presented that is favorable to the mid-inlet approach. Parasol wing, confined flow field, and spatula-like cruise missile configurations were examined with strategic applications in mind. The preliminary results are encouraging with respect to aerodynamic and volumetric efficiency and choice of engine integration schemes.

  3. Frontonasal dysplasia, macroblepharon, eyelid colobomas, ear anomalies, macrostomia, mental retardation and CNS structural anomalies: defining the phenotype.

    PubMed

    Guion-Almeida, M L; Richieri-Costa, A

    2001-04-01

    We report a Brazilian boy, born to normal and nonconsanguineous parents showing, among other signs, brachycephaly, a wide forehead, a widow's peak, hypertelorism, wide palpebral fissures with multiple eyelid colobomas, a broad nasal root, a long philtrum, macrostomia, prominent lips, a high arched palate, a midline alveolar cleft, a small and grooved chin, ear anomalies, structural anomaly of the corpus callosum, and mental retardation. To our knowledge this additional patient defines a particular clinical condition previously reported [Guion-Almeida M.L. Richieri-Costa A. (1999) Clinical Dysmorphol 8;1-4; Masuno M. et al. (2000) Clin Dysmorphol 9:59-60].

  4. Helping a boy with chronic medical problems get on friendly terms with his body and puberty.

    PubMed

    Todd, Victoria

    2012-01-01

    "My mom wants me to shave off my facial hair, but I like it. I think it makes me look mature," said sixteen-year-old Alex as he proudly stroked the crop of hairs sprouting from his chin. I was speechless. Why? Because for years I had heard about all the medical things that were wrong with Alex's body. Then, when puberty arrived, his distress about his changing body was intense. So how did psychoanalysis help him get on friendly terms with body changes, even enjoying signs of growing up? We shall see.

  5. Maximizing results in reconstruction of cheek defects.

    PubMed

    Mureau, Marc A M; Hofer, Stefan O P

    2009-07-01

    The face is exceedingly important, as it is the medium through which individuals interact with the rest of society. Reconstruction of cheek defects after trauma or surgery is a continuing challenge for surgeons who wish to reliably restore facial function and appearance. Important in aesthetic facial reconstruction are the aesthetic unit principles, by which the face can be divided in central facial units (nose, lips, eyelids) and peripheral facial units (cheeks, forehead, chin). This article summarizes established options for reconstruction of cheek defects and provides an overview of several modifications as well as tips and tricks to avoid complications and maximize aesthetic results.

  6. Suppression of Stimulated Brillouin Scattering in Optical Fibers Using a Linearly Chirped Diode Laser

    DTIC Science & Technology

    2012-07-02

    modulation n,” Chin. Opt. Lett. 7, 29–31 (2009). 3 . D. Brown, M. Dennis, and W. Torruellas, “Improved phase modulation for SBS mitigation in kW -class fiber ...D. Björk, I. Majid, and K. Tankala, “ kW class, narrow-linewidth, counter pumped fiber amplifiers,” Solid State and Diode Laser Technical Review, 17...Suppression of stimulated Brillouin scattering in optical fibers using a linearly chirped diode laser J. O. White, 1,* A. Vasilyev, 2 J. P

  7. Photoelectric Ozonometers

    DTIC Science & Technology

    1961-05-19

    amplification factors of the amplifiers of Instrument No. 3, installed 12 - Fig. 3. Ozonograph with diffraction gratings. e i :I - -’D Fig. 4. Block...respectively. ൜ - F,.g. 9. Dependence of S l og ..-- ••) F.k calculated according to the data of Figure 8. "---21 --- for e &oh Instrument separately. The...A- log It (rel. units) 1) El’brus .= 4000-A; P) E l’brus, = 3200 1; 3) Chinli, A = 3600 * 4) Tashkent, ý = 1600 •; 5) Tashkent, A = = 3200 2; 6

  8. Microbial Methane Fermentation Kinetics for Toxicant Exposure.

    DTIC Science & Technology

    1981-08-31

    usually occurs. This stimulatory concentration may range from only a fraction of a mg/i for some heavy metals to several hundred mg/ l for sodium or calcium...the addition of 200 mg/ l sulfide. It is important to note that under anaerobic conditions, in a mixed culture of bacteria, sulfate is reduced to...Chin (1971) indicated that soluble metal concentrations of a few mg/ l are all that is necessary to shut down 8 ,’ gas production. Unlike most prior

  9. GENERAL: A modified weighted probabilistic cellular automaton traffic flow model

    NASA Astrophysics Data System (ADS)

    Zhuang, Qian; Jia, Bin; Li, Xin-Gang

    2009-08-01

    This paper modifies the weighted probabilistic cellular automaton model (Li X L, Kuang H, Song T, et al 2008 Chin. Phys. B 17 2366) which considered a diversity of traffic behaviors under real traffic situations induced by various driving characters and habits. In the new model, the effects of the velocity at the last time step and drivers' desire for acceleration are taken into account. The fundamental diagram, spatial-temporal diagram, and the time series of one-minute data are analyzed. The results show that this model reproduces synchronized flow. Finally, it simulates the on-ramp system with the proposed model. Some characteristics including the phase diagram are studied.

  10. Maritime Aerosol Network (MAN) as a Component of AERONET

    NASA Technical Reports Server (NTRS)

    Smirnov, A.; Holben, B. N.; Slutsker, I.; Giles, D. M.; McClain, C. R.; Eck, T. F.; Sakerin, S. M.; Macke, A.; Croot, P.; Zibordi, G.; Quinn, P. K.

    2008-01-01

    The World Ocean produces a large amount of natural aerosols that have all impact on the Earth's albedo and climate. Sea-salt is the major contributor to aerosol optical depth over the oceans. [Mahowald et al. 2006; Chin et al. 2002; Satheesh et al. 1999; Winter and Chylek, 1997] and therefore affects the radiative balance over the ocean through the direct [Haywood et al. 1999] and indirect aerosol effect [O'Dowd et al. 1999]. Aerosols over the oceans (produced marine and advected from land sources) are important for various atmospheric processes [Lewis and Schwartz, 2004] and remote sensing studies [Gordon, 1997].

  11. [Mutation in the ED1, Ala349Thr in a patient with X-linked hypohidrotic ectodermal dysplasia].

    PubMed

    Salas-Alanis, Julio C; Cepeda-Valdés, Rodrigo; González-Santos, Adriana; Amaya-Guerra, Mario; Kurban, Mazen; Christiano, Angela M

    2011-12-01

    Hypohidrotic ectodermal dysplasia (HED) is a very rare disease characterized by the absence of eccrine glands, dry skin, scanty hair, and dental abnormalities. It is caused by mutations within the ED1 gene, which encodes a protein, ectodysplasin-A (EDA). Clinical characteristic are frontal bossing, saddle nose, pointed chin, a prominent supraorbital ridge with periorbital hyperpigmenta-tion, and anodontia. Those affected show great intolerance to heat. We report the first Mexican 2-year-old boy with an Ala349Thr missense mutation from Tamaulipas, México.

  12. Three-dimensional printer-assisted reduction genioplasty; surgical guide fabrication

    PubMed Central

    Keyhan, Seied Omid; Jahangirnia, Alireza; Fallahi, Hamid Reza; Navabazam, Alireza; Ghanean, Sina

    2016-01-01

    Genioplasty is a common operation to enhance function and appearance of the chin, the most prominent part of the lower third of the face, which has major impact on character impressions and facial beauty. However, since transference of preconfigured accurate treatment plans to patients during operation is difficult, sometimes it can be challenging, especially for inexperienced surgeons. This article represents a simplified technique to perform reduction genioplasty by utilizing a customized genioplasty guide manufactured with three-dimensional printing technology. This approach is helpful to achieve more precise and safer outcomes with fewer complications. PMID:28299271

  13. Cryptanalysis and Improvement on "Robust EPR-Pairs-Based Quantum Secure Communication with Authentication Resisting Collective Noise"

    NASA Astrophysics Data System (ADS)

    Yue, Qiu-Ling; Yu, Chao-Hua; Liu, Bin; Wang, Qing-Le

    2016-10-01

    Recently, Chang et al. [Sci Chin-Phys Mech Astron. 57(10), 1907-1912, 2014] proposed two robust quantum secure communication protocols with authentication based on Einstein-Podolsky-Rosen (EPR) pairs, which can resist collective noise. In this paper, we analyze the security of their protocols, and show that there is a kind of security flaw in their protocols. By a kind of impersonation attack, the eavesdropper can obtain half of the message on average. Furthermore, an improved method of their protocols is proposed to close the security loophole.

  14. Morgellons Disease

    PubMed Central

    Ohn, Jungyoon; Park, Seon Yong; Moon, Jungyoon; Choe, Yun Seon

    2017-01-01

    Morgellons disease is a rare disease with unknown etiology. Herein, we report the first case of Morgellons disease in Korea. A 30-year-old woman presented with a 2-month history of pruritic erythematous patches and erosions on the arms, hands, and chin. She insisted that she had fiber-like materials under her skin, which she had observed through a magnifying device. We performed skin biopsy, and observed a fiber extruding from the dermal side of the specimen. Histopathological examination showed only mild lymphocytic infiltration, and failed to reveal evidence of any microorganism. The polymerase chain reaction for Borrelia burgdorferi was negative in her serum. PMID:28392653

  15. The Installation Restoration Program Toxicology Guide. Volume 3

    DTIC Science & Technology

    1987-06-01

    their lifetime. A total of 224 mice were in the control groups. In both the parent and offspring generations there was an excess of mortality from week 60...was actributed to a reduction in testosterone (1966). Exposure to DDT through maternal milk has been found to have lasting effects on micý and rats. The...any self-contained breathing apparatus * 100-500 mg/m 3 : A gas mask with a chin- style or a front- or back-mounted organic vapor canister and dust

  16. Revisiting Deng et al.'s Multiparty Quantum Secret Sharing Protocol

    NASA Astrophysics Data System (ADS)

    Hwang, Tzonelih; Hwang, Cheng-Chieh; Yang, Chun-Wei; Li, Chuan-Ming

    2011-09-01

    The multiparty quantum secret sharing protocol [Deng et al. in Chin. Phys. Lett. 23: 1084-1087, 2006] is revisited in this study. It is found that the performance of Deng et al.'s protocol can be much improved by using the techniques of block-transmission and decoy single photons. As a result, the qubit efficiency is improved 2.4 times and only one classical communication, a public discussion, and two quantum communications between each agent and the secret holder are needed rather than n classical communications, n public discussions, and 3n/2 quantum communications required in the original scheme.

  17. Survey of Pre- and Postprocessing Structural Anlaysis Software.

    DTIC Science & Technology

    1980-08-05

    first element. Page - 7 Gray et al.[28 describe two methods for automatic :enumbering of nodes for water network analysis. The method can be extended...Nat’l. Conf., ACM, Publication, Z. 69, 1969. 28. R.K.L. Gay, K.K. Chin, S.S. Chua, C.H. Chan and S.Y. So, Node Reordering Algorithms for Water ... Network Analysis, :nt. J. for Num. Meth. in Engng., Vol. 12, p. 1241-1259, 1978. 29. Preiss, K., Checking of the Topological Consistency of a Finite Element

  18. [Conservative treatment of a case of periapical lesion with complications. Report of a case and calcium hydroxide therapy].

    PubMed

    Maráz, K; Gorzó, I; Olasz, T; Kapros, P

    1998-11-01

    A case and treatment of extraoral fistula on the chin-caused by necrotic pulp of lower left canine--is being presented. In this case an endodontic origin should always be considered from the aspect of differential diagnosis. Nonsurgical endodontic therapy, sometimes complimented by surgery, or extraction are the treatment modalities of these cases. For the treatment calcium hydroxide powder mixed with chlorhexidin gluckonat (0.1%) was used. Usage of calcium hydroxide paste was leaded to rapid and successful healing of extraoral lesions communicating with necrotic tooth.

  19. An Assessment of Peridynamics for Pre and Post Failure Deformation

    DTIC Science & Technology

    2011-11-01

    Progressive Damage Prediction in Center-Cracked Composite Laminates. Composite Struct. 2009, 90, 141–151. 7. Foster, J. T.; Silling, S. A.; Chen, W . W ...ALBUQUERQUE NM 87185-0836 4 US ARMY ARDEC ATTN RDAR MEE W C CHIN ATTN RDAR MEE W D PFAU ATTN RDAR MEE W G STUNZENAS ATTN RDAR...MEE W E BAKER BLDG 3022 PICATINNY ARSENAL NJ 07806-5000 3 US ARMY ARDEC ATTN RDAR MEF E D CARLUCCI ATTN RDAR MEF E D GEISSLER

  20. Osteotomy and osteosynthesis in complex segmental genioplasty with double surgical guide

    PubMed Central

    Assis, Adriano; Olate, Sergio; Asprino, Luciana; de Moraes, Márcio

    2014-01-01

    Chin osteotomy is used in esthetic and functional procedure; genioplasty shows different surgical options as lineal osteotomy, curved osteotomy, segmental osteotomy and others for different conditions of the face. This communication shows the use of two surgical guides used in a patient with extremely facial asymmetry; the surgical plan was realized in a stereolithographic biomodel. The first surgical guide was used for osteotomy and the second surgical guide was used for putting the plate, previously bent, and for segmented osteotomy in the planned position on the biomodel; this technique showed adequate adaptation and security in this extremely asymmetric case. The potential use of this surgical guide was discussed. PMID:24995074

  1. Peroxidase-like oxidative activity of a manganese-coordinated histidyl bolaamphiphile self-assembly

    NASA Astrophysics Data System (ADS)

    Kim, Min-Chul; Lee, Sang-Yup

    2015-10-01

    A peroxidase-like catalyst was constructed through the self-assembly of histidyl bolaamphiphiles coordinated to Mn2+ ions. The prepared catalyst exhibited oxidation activity for the organic substrate o-phenylenediamine (OPD) in the presence of hydrogen peroxide (H2O2). The histidyl bolaamphiphiles of bis(N-alpha-amido-histidine)-1,7-heptane dicarboxylates self-assembled to make spherical structures in an aqueous solution. Subsequent association of Mn2+ ions with the histidyl imidazoles in the self-assembly produced catalytic active sites. The optimal Mn2+ ion concentration was determined and coordination of the Mn2+ ion with multiple histidine imidazoles was investigated using spectroscopy analysis. The activation energy of the produced catalysts was 55.0 kJ mol-1, which was comparable to other peroxidase-mimetic catalysts. A detailed kinetics study revealed that the prepared catalyst followed a ping-pong mechanism and that the turnover reaction was promoted by increasing the substrate concentration. Finally, application of the prepared catalyst for glucose detection was demonstrated through cascade enzyme catalysis. This study demonstrated a facile way to prepare an enzyme-mimetic catalyst through the self-assembly of an amphiphilic molecule containing amino acid segments.A peroxidase-like catalyst was constructed through the self-assembly of histidyl bolaamphiphiles coordinated to Mn2+ ions. The prepared catalyst exhibited oxidation activity for the organic substrate o-phenylenediamine (OPD) in the presence of hydrogen peroxide (H2O2). The histidyl bolaamphiphiles of bis(N-alpha-amido-histidine)-1,7-heptane dicarboxylates self-assembled to make spherical structures in an aqueous solution. Subsequent association of Mn2+ ions with the histidyl imidazoles in the self-assembly produced catalytic active sites. The optimal Mn2+ ion concentration was determined and coordination of the Mn2+ ion with multiple histidine imidazoles was investigated using spectroscopy

  2. Cervical range of movement in relation to neck dimension.

    PubMed

    Reynolds, Jeremy; Marsh, D; Koller, Heiko; Zenenr, Juliane; Bannister, G

    2009-06-01

    The authors investigated the effect of neck dimension upon cervical range of motion. Data relating to 100 healthy subjects, aged between 20 and 40 years, were recorded with respect to age, gender and range of motion in three planes. Additionally, two widely used methods of measuring neck motion, chin-sternal distance and uniplanar goniometer, were assessed against a validated measurement tool, the 'CROM goniometer'. Using multiple linear regression analysis it was determined that sagittal flexion (P = 0.002) and lateral rotation (P < 0.0001) were most closely related to neck circumference alone whereas lateral flexion (P < 0.0001) was most closely related to a ratio of circumference and length of neck. Hence, assessing cervical range of motion as outcome variable or as a measure at posttreatment follow-up, neck circumference was shown to be one of the factors influencing total neck motion, particularly sagittal flexion and lateral tilt. Comparison of cervical range of motion assessed with a validated measurement tool, the CROM goniometer, with results of both frequently applied clinician's instruments, the uniplanar goniometer and measurement of chin-sternal distance, showed low reliability with the latter techniques, and motion values measured with these techniques should be interpreted with caution if using them for comparison of cervical range of motion of alike groups. We demonstrated that neck dimension should be incorporated into cervical functional outcome assessment and one should be wary about recorded values for neck motion from non-validated measurement tools.

  3. Modelling of facial growth in Czech children based on longitudinal data: Age progression from 12 to 15 years using 3D surface models.

    PubMed

    Koudelová, Jana; Dupej, Ján; Brůžek, Jaroslav; Sedlak, Petr; Velemínská, Jana

    2015-03-01

    Dealing with the increasing number of long-term missing children and juveniles requires more precise and objective age progression techniques for the prediction of their current appearance. Our contribution includes detailed and real facial growth information used for modelling age progression during adolescence. This study was based on an evaluation of the overall 180 three-dimensional (3D) facial scans of Czech children (23 boys, 22 girls), which were longitudinally studied from 12 to 15 years of age and thus revealed the real growth-related changes. The boys underwent more marked changes compared with the girls, especially in the regions of the eyebrow ridges, nose and chin. Using modern geometric morphometric methods, together with their applications, we modelled the ageing and allometric trajectories for both sexes and simulated the age-progressed effects on facial scans. The facial parts that are important for facial recognition (eyes, nose, mouth and chin) all deviated less than 0.75mm, whereas the areas with the largest deviations were situated on the marginal parts of the face. The mean error between the predicted and real facial morphology obtained by modelling the children from 12 to 15 years of age was 1.92mm in girls and 1.86mm in boys. This study is beneficial for forensic artists as it reduces the subjectivity of age progression methods.

  4. Diarrheal illnesses: a public health perspective.

    PubMed

    Ocfemia, Cheryl Bañez; Taylor, Candace

    2004-04-01

    Diarrheal illnesses remain among the leading causes of morbidity in the United States. Approximately five million diarrheal cases occur annually (Chin, 2000; Ostroff & Leduc, 2000), with an estimated incidence of one diarrheal episode per person per year (Aranda-Michel & Giannella, 1999). Though the causes of diarrheal illnesses vary, infectious agents account for a majority of cases (Aranda-Michel & Giannella, 1999; Chin, 2000; Ostroff & Leduc, 2000). Most diarrhea-causing infectious agents are transmitted through food, water, or person-to-person via the fecal-oral route and are the cause of numerous diarrheal outbreaks. The risk for exposure to such pathogens within the general population is universal; however, persons in pediatric, geriatric, and other immunocompromised populations are at increased risk for subsequent illness and complications (Centers for Disease Control and Prevention, 2001; Ostroff & Leduc, 2000). Moreover, many persons with diarrheal illness do not seek medical care and self-treat with over-the-counter antidiarrheal agents, which have potentially serious side effects among high-risk individuals. The public health impact of diarrheal illness is apparent and emphasizes the need for early diagnosis and appropriate treatment, timely notification of illness with public health implications, and coordination between healthcare professionals and public health officials to prevent and control the spread of infection.

  5. Congenital muscular torticollis in adult patients: literature review and a case report using a harmonic scalpel.

    PubMed

    Pombo Castro, María; Luaces Rey, Ramón; Vázquez Mahía, Inés; López-Cedrún Cembranos, José Luís

    2014-02-01

    Congenital torticollis is characterized by shortening and fibrosis of the sternocleidomastoid (SCM) muscle detected at birth or shortly after birth. This leads to a lateral inclination of the head to the ipsilateral shoulder and chin deviation to the opposite side. When diagnosed early, most cases can be conservatively managed with excellent results. In neglected adult cases, the treatment of this entity is more controversial. A review of the different treatment options in neglected adult cases of congenital torticollis is presented, and a case successfully treated by SCM bipolar release is reported. A 35-year-old woman diagnosed with congenital torticollis was referred to the authors' department. She had been diagnosed at 32 years of age and had been conservatively treated, with no success. Physical examination showed a posterior region of the left SCM muscle hard to palpation, with head tilt to the same side and chin deviation to the right. Bipolar release of the SCM muscle was performed under general anesthesia using the harmonic scalpel. Immobilization with a brace was applied during the first 2 weeks and manual stretching was performed after removal of the brace. Head tilt and movement limitation were resolved, achieving good functional and cosmetic results. Although the best treatment results in congenital torticollis are achieved during the first years of childhood, bipolar release of the SCM muscle followed by postsurgical physical therapy can be effective in neglected adult cases.

  6. One-year assessment of surgical outcomes in Class III patients using cone beam computed tomography

    PubMed Central

    de Paula, L.K.; de Oliveira Ruellas, A.C.; Paniagua, B.; Styner, M.; Turvey, T.; Zhu, H.; Wang, J.; Cevidanes, L.H.S.

    2014-01-01

    The purpose of this study was to apply a novel method to evaluate surgical outcomes at 1 year after orthognathic surgery for Class III patients undergoing two different surgical protocols. Fifty patients divided equally into two groups (maxillary advancement only and combined with mandibular setback) had cone beam computed tomography (CBCT) scans taken pre-surgery, at splint removal, and at 1-year post-surgery. An automatic cranial base superimposition method was used to register, and shape correspondence was applied to assess, the overall changes between pre-surgery and splint removal (surgical changes) and between splint removal and 1-year post-surgery at the end of orthodontic treatment (post-surgical adaptations). Post-surgical maxillary adaptations were exactly the same for both groups, with 52% of the patients having changes >2 mm. Approximately half of the post-surgical changes in the maxilla for both groups were vertical. The two-jaw group showed significantly greater surgical and post-surgical changes in the ramus, chin, and most of the condylar surfaces (P < 0.05). Post-surgical adaptation on the anterior part of the chin was also more significant in the two-jaw group (P < 0.05). Regardless of the type of surgery, marked post-surgical adaptations were observed in the regions evaluated, which explain the adequate maxillary–mandibular relationship at 1-year post-surgery on average, with individual variability. PMID:23403336

  7. Cephalometric evaluation of the craniofacial complex in patients treated with an intraoral distraction osteogenesis device

    PubMed Central

    Chow, Angela; Lee, Hao-Fu; Trahar, Mary; Kawamoto, Henry; Vastardis, Heleni; Ting, Kang

    2009-01-01

    Introduction Distraction osteogenesis has gained popularity because of the hypothesized concurrent soft-tissue expansion, which is believed to reduce postoperative relapse. Although many articles describe the immediate success of mandibular distraction, little research has been done on its long-term stability. Our goal was to examine the long-term craniofacial changes after distraction. Methods Four hemifacial microsomic patients treated with unilateral mandibular distraction were recalled. Changes in maxillary width and height, occlusal height, ramus height, mandibular length, and chin position were quantified by using the posteroanterior and 45° lateral oblique cephalographs. Predistraction and postdistraction measurements were taken over a 5-year period. The data were analyzed by using paired t tests and ANOVA. Results Maxillary height, ramus height, mandibular length, and chin point deviation all experienced moderate improvement after distraction. Although the growth patterns between the control side and the treated side were comparable until 2 years after removal of the device, the normal side outgrew the affected side thereafter until 5 years after distraction. Conclusions Because of the greater inherent growth potential of the unaffected side, more overcorrection than originally believed is needed to offset the persistent asymmetry in growing hemifacial microsomia patients who undergo unilateral distraction osteogenesis. PMID:19061798

  8. Honest sexual signaling in turtles: experimental evidence of a trade-off between immune response and coloration in red-eared sliders Trachemys scripta elegans.

    PubMed

    Ibáñez, Alejandro; Polo-Cavia, Nuria; López, Pilar; Martín, José

    2014-10-01

    Sexual signals can be evolutionarily stable if they are honest and condition dependent or costly to the signaler. One possible cost is the existence of a trade-off between maintaining the immune system and the elaboration of ornaments. This hypothesis has been experimentally tested in some groups of animals but not in others such as turtles. We experimentally challenged the immune system of female red-eared sliders Trachemys scripta elegans, with a bacterial antigen (lipopolysaccharide (LPS)) without pathogenic effects to explore whether the immune activation affected visual colorful ornaments of the head. The LPS injection altered the reflectance patterns of color ornaments. In comparison to the control animals, the yellow chin stripes of injected animals exhibited (1) reduced brightness, (2) lower long wavelength (>470 nm) reflectance, and (3) lower values for carotenoid chroma. The postorbital patches of injected individuals also showed reduced very long wavelength (>570 nm) reflectance but did not change in carotenoid chroma. Thus, experimental turtles showed darker and less "yellowish" chin stripes and less "reddish" postorbital patches at the end of the experiment, whereas control turtles did not change their coloration. This is the first experimental evidence supporting the existence of a trade-off between the immune system and the expression of visual ornaments in turtles. We suggest that this trade-off may allow turtles to honestly signal individual quality via characteristics of coloration, which may have an important role in intersexual selection processes.

  9. Honest sexual signaling in turtles: experimental evidence of a trade-off between immune response and coloration in red-eared sliders Trachemys scripta elegans

    NASA Astrophysics Data System (ADS)

    Ibáñez, Alejandro; Polo-Cavia, Nuria; López, Pilar; Martín, José

    2014-10-01

    Sexual signals can be evolutionarily stable if they are honest and condition dependent or costly to the signaler. One possible cost is the existence of a trade-off between maintaining the immune system and the elaboration of ornaments. This hypothesis has been experimentally tested in some groups of animals but not in others such as turtles. We experimentally challenged the immune system of female red-eared sliders Trachemys scripta elegans, with a bacterial antigen (lipopolysaccharide (LPS)) without pathogenic effects to explore whether the immune activation affected visual colorful ornaments of the head. The LPS injection altered the reflectance patterns of color ornaments. In comparison to the control animals, the yellow chin stripes of injected animals exhibited (1) reduced brightness, (2) lower long wavelength (>470 nm) reflectance, and (3) lower values for carotenoid chroma. The postorbital patches of injected individuals also showed reduced very long wavelength (>570 nm) reflectance but did not change in carotenoid chroma. Thus, experimental turtles showed darker and less "yellowish" chin stripes and less "reddish" postorbital patches at the end of the experiment, whereas control turtles did not change their coloration. This is the first experimental evidence supporting the existence of a trade-off between the immune system and the expression of visual ornaments in turtles. We suggest that this trade-off may allow turtles to honestly signal individual quality via characteristics of coloration, which may have an important role in intersexual selection processes.

  10. Duplication of 20qter and deletion of 20pter due to paternal pericentric inversion: patient report and review of 20qter duplications.

    PubMed

    Starr, Lois J; Truemper, Edward J; Pickering, Diane L; Sanger, Warren G; Olney, Ann Haskins

    2014-08-01

    Duplications of the terminal long arm of chromosome 20 are rare chromosomal anomalies. We report a male infant found on array comparative genomic hybridization analysis to have a 19.5 Mb duplication of chromosome 20q13.12-13.33, as well as an 886 kb deletion of 20p13 at 18,580-904,299 bp. This anomaly occurred as the recombinant product of a paternal pericentric inversion. There have been 23 reported clinical cases involving 20qter duplications; however, to our knowledge this is only the second reported patient with a paternal pericentric inversion resulting in 46,XY,rec(20)dup(20q). This patient shares many characteristics with previously described patients with 20qter duplications, including microphthalmia, anteverted nares, long ears, cleft palate, small chin, dimpled chin, cardiac malformations, and normal intrauterine growth. While there is variable morbidity in patients with terminal duplications of 20q, a review of previously reported patients and comparison to our patient's findings shows significant phenotypic similarity.

  11. The effect of violin playing on the bony facial structures in adolescents.

    PubMed

    Kovero, O; Könönen, M; Pirinen, S

    1997-08-01

    Holding a violin between shoulder and chin needs a special kind of muscle function. The purpose of this investigation was to determine whether this kind of muscular activity is a modifying factor for facial growth in adolescence. The bony facial dimensions of 24 adolescent violin students attending colleges of music with a playing history of 5-11 years were measured from lateral and posteroanterior cephalograms and panoramic tomograms of the jaws. The dimensions were compared with those of sex- and age-matched controls. Significant differences were found between violin players and controls. The players had higher faces, especially on the right side of the lower face and in the right mandibular ramus. The players also had more proclined upper and lower incisors than the controls. It is concluded that the overall greater facial height in violinists reflects the increased face muscle activity and the higher bony dimensions of the right side of the face are due to the muscular activity produced on that side to balance the load caused by the violin on the left. The greater proclination of the incisors is the result of an altered balance of muscular activity between tongue and lip, and the pressure of the violin to the chin.

  12. Acute generalized exanthematous pustulosis (AGEP) due to exposure to sulfuric acid and bromic acid vapor: a case report.

    PubMed

    Bilac, Dilek Bayraktar; Ermertcan, Aylin Turel; Ozturkcan, Serap; Sahin, M Turhan; Temiz, Peyker

    2008-01-01

    Acute generalized exanthematous pustulosis (AGEP, toxic pustuloderma, pustular drug eruption) is a not uncommon cutaneous reaction pattern that is usually related to drug administration. The eruption is of sudden onset and appears 7-10 days after the medication is started. A 22-year-old male patient who was a student at a chemical faculty attended our outpatient clinic with a complaint of pustular eruption on his face. According to his history, the eruption started with pruritus and erythema on his chin 3 days ago and spread to his face and chest. He explained that he had performed an experiment with sulfuric acid and bromic acid and was exposed to their vapor. His dermatological examination revealed erythema and pustules on his cheeks, on his chin, above his upper lip, and on his eyebrows. He also had a few pustules on his chest. There were no ocular, mucous membrane, or pulmonary symptoms. Histopathological examination of the skin biopsy specimen revealed superficial orthokeratosis, focal subcorneal pustule formation, and perivascular chronic inflammatory cell infiltration in superficial dermis. After administration of systemic antihistamines and wet dressing topically, we observed rapid healing of the lesions. Because there was no systemic drug intake in his history, we were concerned that exposure to sulfuric acid and bromic acid vapor caused AGEP in this patient. We present this rare case to show that the vapor of chemical materials may cause AGEP or other drug eruptions.

  13. A genome-wide association scan implicates DCHS2, RUNX2, GLI3, PAX1 and EDAR in human facial variation.

    PubMed

    Adhikari, Kaustubh; Fuentes-Guajardo, Macarena; Quinto-Sánchez, Mirsha; Mendoza-Revilla, Javier; Camilo Chacón-Duque, Juan; Acuña-Alonzo, Victor; Jaramillo, Claudia; Arias, William; Lozano, Rodrigo Barquera; Pérez, Gastón Macín; Gómez-Valdés, Jorge; Villamil-Ramírez, Hugo; Hunemeier, Tábita; Ramallo, Virginia; Silva de Cerqueira, Caio C; Hurtado, Malena; Villegas, Valeria; Granja, Vanessa; Gallo, Carla; Poletti, Giovanni; Schuler-Faccini, Lavinia; Salzano, Francisco M; Bortolini, Maria-Cátira; Canizales-Quinteros, Samuel; Cheeseman, Michael; Rosique, Javier; Bedoya, Gabriel; Rothhammer, Francisco; Headon, Denis; González-José, Rolando; Balding, David; Ruiz-Linares, Andrés

    2016-05-19

    We report a genome-wide association scan for facial features in ∼6,000 Latin Americans. We evaluated 14 traits on an ordinal scale and found significant association (P values<5 × 10(-8)) at single-nucleotide polymorphisms (SNPs) in four genomic regions for three nose-related traits: columella inclination (4q31), nose bridge breadth (6p21) and nose wing breadth (7p13 and 20p11). In a subsample of ∼3,000 individuals we obtained quantitative traits related to 9 of the ordinal phenotypes and, also, a measure of nasion position. Quantitative analyses confirmed the ordinal-based associations, identified SNPs in 2q12 associated to chin protrusion, and replicated the reported association of nasion position with SNPs in PAX3. Strongest association in 2q12, 4q31, 6p21 and 7p13 was observed for SNPs in the EDAR, DCHS2, RUNX2 and GLI3 genes, respectively. Associated SNPs in 20p11 extend to PAX1. Consistent with the effect of EDAR on chin protrusion, we documented alterations of mandible length in mice with modified Edar funtion.

  14. Petrography and Mineralogy of 18 Newly Recovered Ordinary Chondrites in China

    NASA Astrophysics Data System (ADS)

    Li, S. L.

    2015-05-01

    Petrology and mineralogy of 18 newly recovered ordinary chondrites in China are reported in this paper. Fifteen meteorites were found in Xinjiang, among which 13 meteorites were found in the Lop Nur desert, and the other 2 meteorites were found in Kumtag and Aksai Chin, respectively. Three other meteorites are observed falls in Xining, Fuhe, and Dongyang, respectively. All meteorites are equilibrated ordinary chondrites with 8 H group and 10 L group meteorites. Their petrographic types vary from 4 to 6 in the L group meteorites, with most being type 5, while all H group meteorites are classified as type 5. The features of shock metamorphism of most meteorites are moderate though a few have features of ≥S4 stage. Most Lop Nur meteorites underwent intense weathering with only two of which have weathering degree of W1 and W2. Both Kumtag and Aksai Chin meteorite have a weathering degree of W2. The newly discovered tens of meteorites in the gobi deserts east to the Taklimakan Desert indicate that this region may become an important dense meteorite collection area in Eurasia.

  15. Contact binaries: II. The importance of deformation caused by rotation and tides to the light curve of a contact binary

    NASA Astrophysics Data System (ADS)

    Luo, ChangQing; Huang, RunQian

    2012-05-01

    The theoretical light curves of contact binaries are calculated with and without putting in the contact binary evolution model. Firstly, we do not use the contact binary evolution model. A comparison of the light curve is performed with and without the deformation caused by rotation and tides. It shows that the light curve presents many differences, especially on the bottom and top. Secondly, we adopt the contact binary model [Huang R Q, et al. Chin J Astron Astrophys, 2007, 7: 235-244; Song H F, et al. Chin J Astron Astrophys, 2007, 7: 539-550] and compute the theoretical light curve with and without rotational and tidal effects by studying three binary systems (with low-, intermediate- and high-mass components). The bottom and top of the theoretical light curves are discussed and compared to observations. The results show that taking into account the rotational effect has a better agreement with observations than without it. Therefore, the deformation of the light curve of contact binaries caused by rotation and tides is very important. Meanwhile, the rotational and tidal effect can advance the start of the semi-detached, contact phase and the time of mass-reversal.

  16. Comment on ``Adiabatic quantum computation with a one-dimensional projector Hamiltonian''

    NASA Astrophysics Data System (ADS)

    Kay, Alastair

    2013-10-01

    The partial adiabatic search algorithm was introduced in Tulsi's paper [Phys. Rev. APLRAAN1050-294710.1103/PhysRevA.80.052328 80, 052328 (2009)] as a modification of the usual adiabatic algorithm for a quantum search with the idea that most of the interesting computation only happens over a very short range of the adiabatic path. By focusing on that restricted range, one can potentially gain an advantage by reducing the control requirements on the system, enabling a uniform rate of evolution. In this Comment, we point out an oversight in Tulsi's paper [Phys. Rev. APLRAAN1050-294710.1103/PhysRevA.80.052328 80, 052328 (2009)] that invalidates its proof. However, the argument can be corrected, and the calculations in Tulsi's paper [Phys. Rev. APLRAAN1050-294710.1103/PhysRevA.80.052328 80, 052328 (2009)] are then sufficient to show that the scheme still works. Nevertheless, subsequent works [Phys. Rev. APLRAAN1050-294710.1103/PhysRevA.82.034304 82, 034304 (2010), Chin. Phys. BCPBHAJ1674-105610.1088/1674-1056/20/4/040309 20, 040309 (2011), Chin. Phys. BCPBHAJ1674-105610.1088/1674-1056/21/1/010306 21, 010306 (2012), AASRI Procedia 1, 5862 (2012), and Quantum Inf. Process.10.1007/s11128-013-0557-1 12, 2689 (2013)] cannot all be recovered in the same way.

  17. Enterococcus species diversity in fecal samples of wild marine species as determined by real-time PCR.

    PubMed

    Medeiros, Aline Weber; Blaese Amorim, Derek; Tavares, Maurício; de Moura, Tiane Martin; Franco, Ana Claudia; d'Azevedo, Pedro Alves; Frazzon, Jeverson; Frazzon, Ana Paula Guedes

    2017-02-01

    Analyses using culture-independent molecular techniques have improved our understanding of microbial composition. The aim of this work was to identify and quantify enterococci in fecal samples of wild marine species using real-time quantitative PCR. Seven Enterococcus species were examined in fecal DNA of South American fur seals (Arctocephalus australis), Subantarctic fur seals (Arctocephalus tropicalis), green turtles (Chelonia mydas), Magellanic penguins (Spheniscus magellanicus), snowy-crowned tern (Sterna trudeaui), white-backed stilt (Himantopus melanurus), white-chinned petrels (Procellaria aequinoctialis), red knot (Calidris canutus), and black-browed albatross (Thalassarche melanophris). All Enterococcus species evaluated were detected in all fecal samples of wild marine species, with a concentration ranging between 10(6) and 10(12) copies/ng of total DNA. Differences in the enterococci distribution were observed. Enterococcus faecalis and Enterococcus mundtii were most abundant in marine mammals. Enterococcus faecalis was frequent in green turtle, Magellanic penguin, snowy-crowned tern, red knot, and black-browed albatross. Enterococcus hirae and Enterococcus gallinarum showed elevated occurrence in white-backed stilt, and Enterococcus faecium in white-chinned petrel. This study showed highest diversity of enterococci in feces of wild marine species than currently available data, and reinforced the use of culture-independent analysis to help us to enhance our understanding of enterococci in gastrointestinal tracts of wild marine species.

  18. Large-Scale Expansion of the Face Representation in Somatosensory Areas of the Lateral Sulcus Following Spinal Cord Injuries in Monkeys

    PubMed Central

    Tandon, Shashank; Kambi, Niranjan; Lazar, Leslee; Mohammed, Hisham; Jain, Neeraj

    2009-01-01

    Transection of dorsal columns of the spinal cord in adult monkeys results in large-scale expansion of the face inputs into the deafferented hand region in the primary somatosensory cortex (area 3b) and the ventroposterior nucleus of thalamus. Here we determined if the upstream cortical areas, secondary somatosensory (S2) and parietal ventral (PV) areas, also undergo reorganization following lesions of the dorsal columns. Areas S2, PV and 3b were mapped after long-term unilateral lesions of the dorsal columns at cervical levels in adult macaque monkeys. In areas S2 and PV, we found neurons responding to touch on the face in regions where normally responses to touch on the hand and other body parts are seen. In the reorganized parts of S2 and PV inputs from the chin as well as other parts of the face were observed, whereas, in area 3b only the chin inputs expand into the deafferented regions. The results show that deafferentations lead to a more widespread brain reorganization than previously known. The data also show that reorganization in areas S2 and PV shares a common substrate with area 3b, but there are specific features that emerge in S2 and PV. PMID:19776287

  19. Obstacle avoidance sonar for submarines

    NASA Astrophysics Data System (ADS)

    Dugas, Albert C.; Webman, Kenneth M.

    2002-05-01

    The Advanced Mine Detection Sonar (AMDS) system was designed to operate in poor environments with high biological and/or shallow-water boundary conditions. It provides increased capability for active detection of volume, close-tethered, and bottom mines, as well as submarine and surface target active/passive detection for ASW and collision avoidance. It also provides bottom topography mapping capability for precise submarine navigation in uncharted littoral waters. It accomplishes this by using advanced processing techniques with extremely narrow beamwidths. The receive array consists of 36 modules arranged in a 15-ft-diameter semicircle at the bottom of the submarine sonar dome to form a chin-mounted array. Each module consists of 40 piezoelectric rubber elements. The modules provide the necessary signal conditioning to the element data prior to signal transmission (uplink) through the hull. The elements are amplified, filtered, converted to digital signals by an A/D converter, and multiplexed prior to uplink to the inboard receiver. Each module also has a downlink over which it receives synchronization and mode/gain control. Uplink and downlink transmission is done using fiberoptic telemetry. AMDS was installed on the USS Asheville. The high-frequency chin array for Virginia class submarines is based on the Asheville design.

  20. Possible Interbreeding in Late Italian Neanderthals? New Data from the Mezzena Jaw (Monti Lessini, Verona, Italy)

    PubMed Central

    Condemi, Silvana; Mounier, Aurélien; Giunti, Paolo; Lari, Martina; Caramelli, David; Longo, Laura

    2013-01-01

    In this article we examine the mandible of Riparo Mezzena a Middle Paleolithic rockshelter in the Monti Lessini (NE Italy, Verona) found in 1957 in association with Charentian Mousterian lithic assemblages. Mitochondrial DNA analysis performed on this jaw and on other cranial fragments found at the same stratigraphic level has led to the identification of the only genetically typed Neanderthal of the Italian peninsula and has confirmed through direct dating that it belongs to a late Neanderthal. Our aim here is to re-evaluate the taxonomic affinities of the Mezzena mandible in a wide comparative framework using both comparative morphology and geometric morphometrics. The comparative sample includes mid-Pleistocene fossils, Neanderthals and anatomically modern humans. This study of the Mezzena jaw shows that the chin region is similar to that of other late Neanderthals which display a much more modern morphology with an incipient mental trigone (e.g. Spy 1, La Ferrassie, Saint-Césaire). In our view, this change in morphology among late Neanderthals supports the hypothesis of anatomical change of late Neanderthals and the hypothesis of a certain degree of interbreeding with AMHs that, as the dating shows, was already present in the European territory. Our observations on the chin of the Mezzena mandible lead us to support a non abrupt phylogenetic transition for this period in Europe. PMID:23544098

  1. Revisiting the Authoritative-Dialogic Tension in Inquiry-Based Elementary Science Teacher Questioning

    NASA Astrophysics Data System (ADS)

    Van Booven, Christopher D.

    2015-05-01

    Building on the 'questioning-based discourse analytical' framework developed by Singapore-based science educator and discourse analyst, Christine Chin, this study investigated the extent to which fifth-grade science teachers' use of questions with either an authoritative or dialogic orientation differentially restricted or expanded the quality and complexity of student responses in the USA. The author analyzed approximately 10 hours of classroom discourse from elementary science classrooms organized around inquiry-based science curricula and texts. Teacher questions and feedback were classified according to their dialogic orientation and contextually inferred structural purpose, while student understanding was operationalized as a dynamic interaction between cognitive process, syntacto-semantic complexity, and science knowledge type. The results of this study closely mirror Chin's and other scholars' findings that the fixed nature of authoritatively oriented questioning can dramatically limit students' opportunities to demonstrate higher order scientific understanding, while dialogically oriented questions, by contrast, often grant students the discursive space to demonstrate a greater breadth and depth of both canonical and self-generated knowledge. However, certain teacher questioning sequences occupying the 'middle ground' between maximal authoritativeness and dialogicity revealed patterns of meaningful, if isolated, instances of higher order thinking. Implications for classroom practice are discussed along with recommendations for future research.

  2. Monitored anesthesia care for great saphenous vein stripping surgery with target controlled infusion of propofol and remifentanil: a prospective study

    PubMed Central

    Cho, Sooyoung; Baik, Hee Jung; Kim, Dong Yeon; Chun, Eun Hee

    2016-01-01

    Background The aim of this study was to determine the appropriate target concentrations at the effect site of propofol and remifentanil when deep sedation was achieved by monitored anesthesia care (MAC) anesthesia and related respiratory depression during vein stripping surgery for varicose veins. Methods In total, 51 adult patients who were scheduled for varicose vein stripping surgery were sedated with propofol and remifentanil during the surgery, after administration of midazolam. Target concentrations at the effect site of the two drugs were changed based on the patient's status. Respiratory support was applied in the order of oxygen supply, chin lift, and assisted mask ventilation. Target concentrations at the effect site of propofol and remifentanil, the need for respiratory support, and a six-point rating scale satisfaction score were the outcome measurements. Results Only one patient did not require oxygen, eight patients needed oxygen alone, 22 patients required use of the chin lift technique, and 20 patients were assisted with mask ventilation. There was no significant difference in the target concentration of propofol or remifentanil between the patients who required mask ventilation and those who did not. Fifty of the 51 patients reported a satisfaction score of 6. Conclusions Although MAC using low target concentrations of propofol and remifentanil during vein stripping surgery was satisfactory to patients, close observation regarding the need for respiratory assistance was necessary. PMID:27066207

  3. Effects of facial hard tissue surgery on facial aesthetics: changes in facial content and frames.

    PubMed

    Choi, Jin-Young; Lee, Sang-Hoon; Baek, Seung-Hak

    2012-11-01

    Aesthetic units of the face can be divided into facial content (FC; eyes, nose, lips, and mouth), anterior facial frame (AFF; a contour line from the trichion, the temporal line of the frontal bone, the lateral orbital rim, the most lateral line of the anterior part of the zygomatic body, the anterior border of the masseter muscle, to the inferior border of the chin), and posterior facial frame (PFF; a contour line from the hairline, the zygomatic arch, to the ramus and gonial angle area of the mandible). The size and shape of each FC and the balance and proportion between FCs create a unique appearance for each person. The facial form can be determined through the combination of AFF and PFF. In the Asian population, clinicians frequently encounter problems of FC (eg, acute nasolabial angle, protrusive and everted lips, nonconsonant lip line, or lip canting), AFF (eg, midface hypoplasia, protrusive and asymmetric chin, vertical deficiency/excess of the anterior maxilla and symphysis, or prominent zygoma), and PFF (eg, square mandibular angle). These problems can be efficiently and effectively corrected through the combination of hard tissue surgery such as anterior segmental osteotomy, genioplasty, mandibular angle reduction, malarplasty, and orthognathic surgery. Therefore, the purposes of this article were to introduce the concepts of FC, AFF, and PFF, and to explain the effects of facial hard tissue surgery on facial aesthetics.

  4. A Case of Linear Lichen Planus Pigmentosus

    PubMed Central

    Seo, Jong Keun; Lee, Hyun Jae; Choi, Joon Hee; Sung, Ho-Suck

    2010-01-01

    Lichen planus pigmentosus (LPP) is chronic pigmentary disorder that shows diffuse or reticulated hyperpigmented, dark brown macules on the sun-exposed areas such as the face, neck and other flexural folds. Clinically, it is different from classical lichen planus because LPP has a longer clinical course and it manifests with dark brown macules. In case of LPP, involvement of the scalp, nail or mucosal area is rare. The histopathological findings of the lesions show an atrophic epidermis, the presence of melanophages and a vacuolar alteration of the basal cell layer with a sparse lymphohistiocytic lichenoid infiltration. Although there have been a few reports of LPP, there have only 3 cases of linear LPP along the lines of Blaschko in the Korean dermatologic literature. Our patient had lesions on the neck and chin with a linear pattern. In this report, we describe a very rare case of LPP with a linear distribution related to Blaschko's lines on the neck and chin areas. PMID:20711271

  5. Cervical Spondylotic Myelopathy Secondary to Dropped Head Syndrome: Report of a Case and Review of the Literature.

    PubMed

    Rahimizadeh, Abolfazl; Soufiani, Housain F; Rahimizadeh, Saghayegh

    2016-01-01

    The dropped head syndrome (DHS) is a disabling condition caused by severe weakness of the neck extensor muscles causing progressive reducible kyphosis of the cervical spine and the inability to hold the head up. Weakness can occur in isolation or in association with a generalized neuromuscular disorder. Isolated cases are owed to the late onset of noninflammatory myopathy designated as INEM, where persistent chin to chest deformity may gradually cause or aggravate preexisting degenerative changes of the cervical spine and ultimately result in myelopathy. In review of the literature, we could find only 5 cases, with no unique guidelines to address the management of these two concomitant pathologies. Herein, a 69-year-old man who had developed cervical myelopathy 2 years after being affected by isolated dropped head syndrome is presented. Chin to chest deformity and cervical myelopathy were managed through three-level anterior cervical discectomy and fusion (ACDF) combined with decompressive cervical laminectomy and stabilization with C2 to C7 pedicle screw-rod construct. At 4-month follow-up, despite recovery in patient's neurological status, flexion deformity reappeared with recurrence of dropped head due to C7 pedicle screws pull-out. However, this was successfully managed with extension of the construct to the upper thoracic levels.

  6. Optical phonetics and visual perception of lexical and phrasal stress in English.

    PubMed

    Scarborough, Rebecca; Keating, Patricia; Mattys, Sven L; Cho, Taehong; Alwan, Abeer

    2009-01-01

    In a study of optical cues to the visual perception of stress, three American English talkers spoke words that differed in lexical stress and sentences that differed in phrasal stress, while video and movements of the face were recorded. The production of stressed and unstressed syllables from these utterances was analyzed along many measures of facial movement, which were generally larger and faster in the stressed condition. In a visual perception experiment, 16 perceivers identified the location of stress in forced-choice judgments of video clips of these utterances (without audio). Phrasal stress was better perceived than lexical stress. The relation of the visual intelligibility of the prosody of these utterances to the optical characteristics of their production was analyzed to determine which cues are associated with successful visual perception. While most optical measures were correlated with perception performance, chin measures, especially Chin Opening Displacement, contributed the most to correct perception independently of the other measures. Thus, our results indicate that the information for visual stress perception is mainly associated with mouth opening movements.

  7. Dietary exposure of Nigerians to mutagens and estrogen-like chemicals.

    PubMed

    Omoruyi, Iyekhoetin Matthew; Ahamioje, Derek; Pohjanvirta, Raimo

    2014-08-15

    Food and drinking water are poorly delineated sources of human exposure to chemical food mutagens and endocrine-disrupting chemicals. In this study, we investigated the presence of mutagens and chemicals exhibiting estrogenic activity in the daily diet of Nigerians, using in vitro assays. Commercially processed foods or snacks and various brands of pure water sachets were extracted by solid-phase extraction and liquid-liquid extraction, respectively. Mutagenicity was determined by the conventional Ames test and two complementary assays on two strains of Salmonella (TA 100 and TA 98), while the estrogenic activity was assessed by a yeast bioluminescent assay, using two recombinant yeast strains (Saccharomyces cerevisiae BMAEREluc/ERα and S. cerevisiae BMA64/luc). A third of the food varieties investigated (chin-chin, hamburger, suya and bean cake) were mutagenic in all three assays, either in the presence or absence of S9 mix. Of the packed water samples, five out of the sixteen investigated (31%), were found to be estrogenic, with estradiol and bisphenol A equivalents ranging from 0.79 to 44.0 ng/L and 124.2 to 1,000.8 ng/L, respectively. Hence, although the current situation in Nigeria does not appear to be substantially worse than, e.g., in Europe, regular monitoring is warranted in the future.

  8. Aeroacoustic sources of motorcycle helmet noise.

    PubMed

    Kennedy, J; Adetifa, O; Carley, M; Holt, N; Walker, I

    2011-09-01

    The prevalence of noise in the riding of motorcycles has been a source of concern to both riders and researchers in recent times. Detailed flow field information will allow insight into the flow mechanisms responsible for the production of sound within motorcycle helmets. Flow field surveys of this nature are not found in the available literature which has tended to focus on sound pressure levels at ear as these are of interest for noise exposure legislation. A detailed flow survey of a commercial motorcycle helmet has been carried out in combination with surface pressure measurements and at ear acoustics. Three potential noise source regions are investigated, namely, the helmet wake, the surface boundary layer and the cavity under the helmet at the chin bar. Extensive information is provided on the structure of the helmet wake including its frequency content. While the wake and boundary layer flows showed negligible contributions to at-ear sound the cavity region around the chin bar was identified as a key noise source. The contribution of the cavity region was investigated as a function of flow speed and helmet angle both of which are shown to be key factors governing the sound produced by this region.

  9. Comparison of Cyberware PX and PS 3D human head scanners

    NASA Astrophysics Data System (ADS)

    Carson, Jeremy; Corner, Brian D.; Crockett, Eric; Li, Peng; Paquette, Steven

    2008-02-01

    A common limitation of laser line three-Dimensional (3D) scanners is the inability to scan objects with surfaces that are either parallel to the laser line or that self-occlude. Filling in missing areas adds some unwanted inaccuracy to the 3D model. Capturing the human head with a Cyberware PS Head Scanner is an example of obtaining a model where the incomplete areas are difficult to fill accurately. The PS scanner uses a single vertical laser line to illuminate the head and is unable to capture data at top of the head, where the line of sight is tangent to the surface, and under the chin, an area occluded by the chin when the subject looks straight forward. The Cyberware PX Scanner was developed to obtain this missing 3D head data. The PX scanner uses two cameras offset at different angles to provide a more detailed head scan that captures surfaces missed by the PS scanner. The PX scanner cameras also use new technology to obtain color maps that are of higher resolution than the PS Scanner. The two scanners were compared in terms of amount of surface captured (surface area and volume) and the quality of head measurements when compared to direct measurements obtained through standard anthropometry methods. Relative to the PS scanner, the PX head scans were more complete and provided the full set of head measurements, but actual measurement values, when available from both scanners, were about the same.

  10. A three-dimensional photogrammetric analysis of the facial esthetics of the Miss Korea pageant contestants

    PubMed Central

    Jang, Kab Soo; Bayome, Mohamed; Park, Jae Hyun; Park, Ki-Ho; Moon, Hong-Beom

    2017-01-01

    Objective The aims of this study were to measure and compare the facial dimensions of the Miss Korea pageant contestants and a selected group of women from the general population by using three-dimensional (3D) image analysis, as well as to compare various facial ratios to the golden ratio within each group. Methods Three-dimensional images of 52 Miss Korea pageant contestants (MK group) and 41 young female adults selected from the general population (GP group) were acquired. Fifty-four variables and ratios were measured and calculated. Intergroup comparisons were performed using multivariate analysis of variance. Results Compared to the GP group, the MK group showed greater total facial height and eye width, lesser lower-facial height, and lesser facial, lower-facial, and nasal widths. Moreover, compared to the GP group, the MK group had more protruded noses with greater nasolabial angle, greater vertical curvature of the foreheads, lesser horizontal curvature of the cheek, and lesser lower-lip-and-chin volume. Conclusions The MK group had longer faces but smaller lower lips and chins than did the GP group. The golden ratio was not matching the current facial esthetic standards. These data might be beneficial for treatment planning of patients undergoing orthognathic and plastic surgeries. PMID:28337418

  11. A new paradigm for the aging Asian face.

    PubMed

    Shirakabe, Yukio; Suzuki, Yoshiro; Lam, Samuel M

    2003-01-01

    Traditionally, Asians have been thought to age more gracefully than Caucasians. The resistance to aging in the Asian patient was credited to the thicker dermis of Asian skin that contains greater collagen and the darker pigment that protects against photoaging. Although these statements are true, the authors propose a new paradigm that explains how the illusion of Asian youthfulness may be understood. The "baby model" purports that the Asian face has many attributes similar to an infant, including a wider and rounder face, higher eyebrow, fuller upper lid, lower nasal bridge, flatter midface, apparently more protuberant lips, and more receded chin. These commonalities between the infant and the Asian compel the viewer to perceive the Asian face as more youthful. However, the Asian face is subjected to a greater amount of gravitational force due to weaker skeletal support, heavier soft tissue, larger amount of malar fat, thicker skin, and a weaker chin. Facial rejuvenative surgery should always be cognizant of the propensity of the Asian skin to unfavorable healing, need for greater tissue suspension, and more conspicuous temporal alopecia. Asian aesthetics that differ and converge with Western ideals are reviewed so that the Western surgeon in particular can comprehend the Asian conception of youthful beauty.

  12. Anatomical differences in response to treatment of port-wine stains by the pulsed dye laser

    NASA Astrophysics Data System (ADS)

    Renfro, Lisa; Geronemus, Roy G.

    1992-06-01

    Two-hundred and fifty-seven patients (136 adults and 121 children) with port-wine stains of the head and neck were treated with the flashlamp-pumped pulsed dye laser. The head and neck was subdivided into 8 anatomical regions (forehead/temple, periorbital, medial cheek, nose, upper cutaneous lip, lateral cheek, chin and neck) which were independently evaluated for response. Response to treatment was found to be associated with the anatomical location of the lesion; in both adults and children the mid-facial region (medial cheek, nose and upper cutaneous lip) responded less favorably to treatment than the other regions of the head and neck (periorbital, forehead/temple, lateral cheek, neck and chin). In adults and children, mean percent lesional lightening of the mid-facial regions was 70.7% compared to 82.3% of the other regions of the head and neck with an estimated difference of 11.6% (95% confidence interval: 8.7% - 14.6%). The mean number of treatments for adults was 3.7, while this number in children was 3.9. All side effects were transient, and included cutaneous depressions, hypopigmentation and hyperpigmentation.

  13. Reliability of EMG normalisation methods for upper-limb muscles.

    PubMed

    Rota, Samuel; Rogowski, Isabelle; Champely, Stéphane; Hautier, Christophe

    2013-01-01

    The study investigated different electromyographic (EMG) normalisation methods for upper-limb muscles. This assessment aimed at comparing the EMG amplitude and the reliability of EMG values obtained with each method. Eighteen male tennis players completed isometric maximal voluntary contractions and dynamic strength exercises (push-ups and chin-ups) on three separate test sessions over at least 7 days. Surface EMG activity of nine upper body muscles was recorded. For each muscle, an analysis of variance for repeated measures was used to compare maximal EMG amplitudes between test conditions. The intra-class correlation coefficient, the coefficient of variation and the standard error of measurement were calculated to determine the EMG reliability of each condition. On the basis of a compromise between maximal EMG amplitude and high reliability, the chin-ups appeared to be the optimal normalisation method for M. latissimus dorsi, M. posterior deltoid, M. biceps brachii, M. flexor carpi radialis and M. extensor carpi radialis. The push-ups seemed relevant to normalise M. anterior deltoid and M. triceps brachii activity, while isometric maximal voluntary contraction remained the most appropriate method for M. pectoralis major and M. middle deltoid. Thus, original methods are proposed to normalise EMG signal of upper-limb muscles.

  14. Taiwanese Political Parties can be Categorized by Face, by Those Who Reported Making Face-To-Trait Inferences

    PubMed Central

    Hu, Shun-Fu; Chang, Chien-Kai; Chen, Yu-Chen; Chien, Sarina Hui-Lin

    2016-01-01

    The present study aims to replicate and extend Rule and Ambady (2010a)'s findings that Republicans and Democrats could be differentiated by face. In Experiment 1, undergraduates categorized 50 gray-scale full-face photos of candidates of the two major political parties in Taiwan, the Kuomingtang (KMT) and the Democratic Progressive Party (DPP). Using identical stimuli and procedure, Experiment 2 tested 25- to 57-year-olds. Experiment 3 tested undergraduates with cropped photos, Experiment 4, with photos devoid of the mouth and chin area. At the end of each Experiment, we interviewed the participants about the strategies used. Results showed that undergraduates could categorize KMT and DPP with accuracies significantly higher than chance in full-face photos (Experiment 1), M = 0.524, p = 0.045, cropped photos (Experiment 3), M = 0.534, p = 0.016, and photos devoid of the mouth-and-chin area (Experiment 4), M = 0.530, p = 0.048. Adults aged between 25 and 57 could also categorize full-face photos (Experiment 2), M = 0.557, p < 0.001. Analysis on strategy use revealed that the better-than-chance performance may be a unique contribution of those who reported making face-to-trait inferences. In sum, we replicated Rule and Ambady's (2010a) results in East Asian and found that face-to-trait inferences may be essential. PMID:26793130

  15. Cervical Spondylotic Myelopathy Secondary to Dropped Head Syndrome: Report of a Case and Review of the Literature

    PubMed Central

    Soufiani, Housain F.; Rahimizadeh, Saghayegh

    2016-01-01

    The dropped head syndrome (DHS) is a disabling condition caused by severe weakness of the neck extensor muscles causing progressive reducible kyphosis of the cervical spine and the inability to hold the head up. Weakness can occur in isolation or in association with a generalized neuromuscular disorder. Isolated cases are owed to the late onset of noninflammatory myopathy designated as INEM, where persistent chin to chest deformity may gradually cause or aggravate preexisting degenerative changes of the cervical spine and ultimately result in myelopathy. In review of the literature, we could find only 5 cases, with no unique guidelines to address the management of these two concomitant pathologies. Herein, a 69-year-old man who had developed cervical myelopathy 2 years after being affected by isolated dropped head syndrome is presented. Chin to chest deformity and cervical myelopathy were managed through three-level anterior cervical discectomy and fusion (ACDF) combined with decompressive cervical laminectomy and stabilization with C2 to C7 pedicle screw-rod construct. At 4-month follow-up, despite recovery in patient's neurological status, flexion deformity reappeared with recurrence of dropped head due to C7 pedicle screws pull-out. However, this was successfully managed with extension of the construct to the upper thoracic levels. PMID:27034870

  16. A genome-wide association scan implicates DCHS2, RUNX2, GLI3, PAX1 and EDAR in human facial variation

    PubMed Central

    Adhikari, Kaustubh; Fuentes-Guajardo, Macarena; Quinto-Sánchez, Mirsha; Mendoza-Revilla, Javier; Camilo Chacón-Duque, Juan; Acuña-Alonzo, Victor; Jaramillo, Claudia; Arias, William; Lozano, Rodrigo Barquera; Pérez, Gastón Macín; Gómez-Valdés, Jorge; Villamil-Ramírez, Hugo; Hunemeier, Tábita; Ramallo, Virginia; Silva de Cerqueira, Caio C.; Hurtado, Malena; Villegas, Valeria; Granja, Vanessa; Gallo, Carla; Poletti, Giovanni; Schuler-Faccini, Lavinia; Salzano, Francisco M.; Bortolini, Maria- Cátira; Canizales-Quinteros, Samuel; Cheeseman, Michael; Rosique, Javier; Bedoya, Gabriel; Rothhammer, Francisco; Headon, Denis; González-José, Rolando; Balding, David; Ruiz-Linares, Andrés

    2016-01-01

    We report a genome-wide association scan for facial features in ∼6,000 Latin Americans. We evaluated 14 traits on an ordinal scale and found significant association (P values<5 × 10−8) at single-nucleotide polymorphisms (SNPs) in four genomic regions for three nose-related traits: columella inclination (4q31), nose bridge breadth (6p21) and nose wing breadth (7p13 and 20p11). In a subsample of ∼3,000 individuals we obtained quantitative traits related to 9 of the ordinal phenotypes and, also, a measure of nasion position. Quantitative analyses confirmed the ordinal-based associations, identified SNPs in 2q12 associated to chin protrusion, and replicated the reported association of nasion position with SNPs in PAX3. Strongest association in 2q12, 4q31, 6p21 and 7p13 was observed for SNPs in the EDAR, DCHS2, RUNX2 and GLI3 genes, respectively. Associated SNPs in 20p11 extend to PAX1. Consistent with the effect of EDAR on chin protrusion, we documented alterations of mandible length in mice with modified Edar funtion. PMID:27193062

  17. Possible interbreeding in late Italian Neanderthals? New data from the Mezzena jaw (Monti Lessini, Verona, Italy).

    PubMed

    Condemi, Silvana; Mounier, Aurélien; Giunti, Paolo; Lari, Martina; Caramelli, David; Longo, Laura

    2013-01-01

    In this article we examine the mandible of Riparo Mezzena a Middle Paleolithic rockshelter in the Monti Lessini (NE Italy, Verona) found in 1957 in association with Charentian Mousterian lithic assemblages. Mitochondrial DNA analysis performed on this jaw and on other cranial fragments found at the same stratigraphic level has led to the identification of the only genetically typed Neanderthal of the Italian peninsula and has confirmed through direct dating that it belongs to a late Neanderthal. Our aim here is to re-evaluate the taxonomic affinities of the Mezzena mandible in a wide comparative framework using both comparative morphology and geometric morphometrics. The comparative sample includes mid-Pleistocene fossils, Neanderthals and anatomically modern humans. This study of the Mezzena jaw shows that the chin region is similar to that of other late Neanderthals which display a much more modern morphology with an incipient mental trigone (e.g. Spy 1, La Ferrassie, Saint-Césaire). In our view, this change in morphology among late Neanderthals supports the hypothesis of anatomical change of late Neanderthals and the hypothesis of a certain degree of interbreeding with AMHs that, as the dating shows, was already present in the European territory. Our observations on the chin of the Mezzena mandible lead us to support a non abrupt phylogenetic transition for this period in Europe.

  18. Use of a mouth-wiping response to reduce drooling by two persons with profound developmental disabilities.

    PubMed

    Lancioni, Giulio E; Singh, Nirbhay N; O'Reilly, Mark F; Sigafoos, Jeff; Pichierri, Sabrina; Iaffaldano, Daniela; Latrofa, Alessandra; Oliva, Doretta

    2008-07-01

    Two men with profound developmental disabilities used a mouth-wiping response instrumental to reduce drooling via a micro-switch-based program (i.e., a program in which the response was automatically monitored and followed by positive stimulation). The wiping response was performed via a napkin or a handkerchief placed inside a belt pocket. The micro-switch technology consisted of two mini-tilt sensors and a radio transmitter hidden inside the napkin, or an optic sensor and a radio transmitter fixed inside the belt pocket. The study was carried out according to a multiple baseline across participants and included a 3-month postintervention check. During the baseline, the participants' mean frequencies of mouth wiping were near zero, and mean percentages of wet chin intervals were about 45 and 50. During the intervention, the mean wiping frequencies increased to 1.6 and 1.9 per min, whereas the mean percentages of wet-chin intervals were mostly below 10. These values were maintained at the postintervention check. Implications of the findings and limitations of the study are discussed.

  19. Evaluation of the 2008 Predictions of Run-Timing and Survival of Wild Migrant Yearling Chinook and Steelhead on the Columbia and Snake Rivers.

    SciTech Connect

    Beer, W. Nicholas; Iltis, Susannah; Anderson, James J.

    2009-01-01

    Columbia Basin Research uses the COMPASS model on a daily basis during the outmigration of Snake River Chinook and steelhead smolts to predict downstream passage and survival. Fish arrival predictions and observations from program RealTime along with predicted and observed environmental conditions are used to make in-season predictions of arrival and survival to various dams in the Columbia and Snake Rivers. For 2008, calibrations of travel and survival parameters for two stocks of fish-Snake River yearling PIT-tagged wild chinook salmon (chin1pit) and Snake River PIT-tagged steelhead (lgrStlhd)-were used to model travel and survival of steelhead and chinook stocks from Lower Granite Dam (LWG) or McNary Dam (MCN) to Bonneville Dam (BON). This report summarizes the success of the COMPASS/RealTime process to model these migrations as they occur. We compared model results on timing and survival to data from two sources: stock specific counts at dams and end-of-season control survival estimates (Jim Faulkner, NOAA, pers. comm. Dec. 16, 2008). The difference between the predicted and observed day of median passage and the Mean Absolute Deviation (MAD) between predicted and observed arrival cumulative distributions are measures of timing accuracy. MAD is essentially the average percentage error over the season. The difference between the predicted and observed survivals is a measure of survival accuracy. Model results and timing data were in good agreement from LWG to John Day Dam (JDA). Predictions of median passage days for the chin1pit and lgrStlhd stocks were 0 and 2 days (respectively) later than observed. MAD for chin1pit and lgrStlhd stocks at JDA were 2.3% and 5.9% (respectively). Between JDA and BON modeling and timing data were not as well matched. At BON, median passage predictions were 6 and 10 days later than observed and MAD values were 7.8% and 16.0% respectively. Model results and survival data were in good agreement from LWG to MCN. COMPASS predicted

  20. Specificity determinants for the two tRNA substrates of the cyclodipeptide synthase AlbC from Streptomyces noursei

    PubMed Central

    Moutiez, Mireille; Seguin, Jérôme; Fonvielle, Matthieu; Belin, Pascal; Jacques, Isabelle Béatrice; Favry, Emmanuel; Arthur, Michel; Gondry, Muriel

    2014-01-01

    Cyclodipeptide synthases (CDPSs) use two aminoacyl-tRNA substrates in a sequential ping-pong mechanism to form a cyclodipeptide. The crystal structures of three CDPSs have been determined and all show a Rossmann-fold domain similar to the catalytic domain of class-I aminoacyl-tRNA synthetases (aaRSs). Structural features and mutational analyses however suggest that CDPSs and aaRSs interact differently with their tRNA substrates. We used AlbC from Streptomyces noursei that mainly produces cyclo(l-Phe-l-Leu) to investigate the interaction of a CDPS with its substrates. We demonstrate that Phe-tRNAPhe is the first substrate accommodated by AlbC. Its binding to AlbC is dependent on basic residues located in the helix α4 that form a basic patch at the surface of the protein. AlbC does not use all of the Leu-tRNALeu isoacceptors as a second substrate. We show that the G1-C72 pair of the acceptor stem is essential for the recognition of the second substrate. Substitution of D163 located in the loop α6–α7 or D205 located in the loop β6–α8 affected Leu-tRNALeu isoacceptors specificity, suggesting the involvement of these residues in the binding of the second substrate. This is the first demonstration that the two substrates of CDPSs are accommodated in different binding sites. PMID:24782519