Impingement thermal performance of perforated circular pin-fin heat sinks
NASA Astrophysics Data System (ADS)
Wen, Mao-Yu; Yeh, Cheng-Hsiung
2018-04-01
The study presents the experimental information on heat transfer performance of jet impingement cooling on circular pin- fin heat sinks with/without a hollow perforated base plate. Smoke flow visualization is also used to investigate the behavior of the complicated flow phenomena of the present heat sinks for this impingement cooling. The effects of flow Reynolds numbers (3458≤Re≤11,526), fin height, the geometry of the heat sinks (with/without a hollow perforated base plate), and jet-to-test heat sink placement (1 ≤ H/ d≤16) are examined. In addition, empirical correlation to estimate the heat transfer coefficient was also developed.
Heat transfer in thin, compact heat exchangers with circular, rectangular, or pin-fin flow passages
NASA Technical Reports Server (NTRS)
Olson, D. A.
1992-01-01
Heat transfer and pressure drop have been measured of three thin, compact heat exchangers in helium gas at 3.5 MPa and higher, with Reynolds numbers of 450 to 36,000. The flow geometries for the three heat exchanger specimens were: circular tube, rectangular channel, and staggered pin fin with tapered pins. The specimens were heated radiatively at heat fluxes up to 77 W/sq cm. Correlations were developed for the isothermal friction factor as a function of Reynolds number, and for the Nusselt number as a function of Reynolds number and the ratio of wall temperature to fluid temperature. The specimen with the pin fin internal geometry had significantly better heat transfer than the other specimens, but it also had higher pressure drop. For certain conditions of helium flow and heating, the temperature more than doubled from the inlet to the outlet of the specimens, producing large changes in gas velocity, density, viscosity, and thermal conductivity. These changes in properties did not affect the correlations for friction factor and Nusselt number in turbulent flow.
Natural convection and radiation heat transfer from an array of inclined pin fins
DOE Office of Scientific and Technical Information (OSTI.GOV)
Alessio, M.E.; Kaminski, D.A.
1989-02-01
Natural convection and radiation from an air-cooled, highly populated pin-fin array were studied experimentally. the effects of pin density, pin length, and the angle of the pin to the horizontal were measured. Previous work by Sparrow and Vemuri treated the case of a vertical base plate with horizontal fins. recently, Sparrow and Vemuri (1986) extended their study to include results for vertical fins with a horizontal down-facing base plate, as well as vertical fins with a horizontal up-facing base plate. In this study, the base plate is maintained in a vertical position and the angle of the pins is variedmore » from the horizontal. The main intent of this study was to compare the performance of inclined pin fins with straight pin fins. In all cases studied, the straight, horizontal fins were superior to the inclined fins. It was possible to obtain a single general correlation of the test data. While this correlation is recommended within the range of parameters that were tested here, one significant parameter, the size of the base plate, was not varied.« less
Enhancement of the forced convective heat transfer on mini pin fin heat sinks with micro spiral fins
NASA Astrophysics Data System (ADS)
Khonsue, Osot
2018-02-01
This research is an experimental study on the characteristics of heat transfer and pressure drop in mini heat sinks using air as the working fluid. The experiments were performed under a constant heat flux ranging from 9.132-13.698 kW/m2 and the air Reynolds number range 322-1982. Three different types of mini heat sinks were rectangle pin fins, cylindrical pin fins, and spiral pin fins with 36x28x9 mm and 5 mm fins high. There were 63 fins altogether and all were made of aluminum. The results showed that the characteristics of the temperature of heat sink of spiral pin fins was the least. Meanwhile the average heat transfer coefficient and Nusselt number of spiral pin fins were the most . Regarding the pressure drop, the rectangular pin fins was the least. The results of this study can be used to guide the design and development of electronic devices cooling system with forced convective heat transfer for higher performance in the future.
NASA Astrophysics Data System (ADS)
Mohammadian, Shahabeddin K.; Zhang, Yuwen
2015-01-01
Three dimensional transient thermal analysis of an air-cooled module that contains prismatic Li-ion cells next to a special kind of aluminum pin fin heat sink whose heights of pin fins increase linearly through the width of the channel in air flow direction was studied for thermal management of Lithium-ion battery pack. The effects of pin fins arrangements, discharge rates, inlet air flow velocities, and inlet air temperatures on the battery were investigated. The results showed that despite of heat sinks with uniform pin fin heights that increase the standard deviation of the temperature field, using this kind of pin fin heat sink compare to the heat sink without pin fins not only decreases the bulk temperature inside the battery, but also decreases the standard deviation of the temperature field inside the battery as well. Increasing the inlet air temperature leads to decreasing the standard deviation of the temperature field while increases the maximum temperature of the battery. Furthermore, increasing the inlet air velocity first increases the standard deviation of the temperature field till reaches to the maximum point, and after that decreases. Also, increasing the inlet air velocity leads to decrease in the maximum temperature of the battery.
Heat transfer coefficients for staggered arrays of short pin fins
NASA Technical Reports Server (NTRS)
Vanfossen, G. J.
1981-01-01
Short pin fins are often used to increase that heat transfer to the coolant in the trailing edge of a turbine blade. Due primarily to limits of casting technology, it is not possible to manufacture pins of optimum length for heat transfer purposes in the trailing edge region. In many cases the pins are so short that they actually decrease the total heat transfer surface area compared to a plain wall. A heat transfer data base for these short pins is not available in the literature. Heat transfer coefficients on pin and endwall surfaces were measured for several staggered arrays of short pin fins. The measured Nusselt numbers when plotted versus Reynolds numbers were found to fall on a single curve for all surfaces tested. The heat transfer coefficients for the short pin fins (length to diameter ratios of 1/2 and 2) were found to be about a factor of two lower than data from the literature for longer pin arrays (length to diameter ratios of about 8).
Local endwall heat/mass-transfer distributions in pin fin channels
NASA Astrophysics Data System (ADS)
Lau, S. C.; Kim, Y. S.; Han, J. C.
1987-10-01
Naphthalene sublimination experiments were conducted to study the effects of the pin configuration, the pin length-to-diameter ratio, and the entrance length on local endwall heat/mass transfer in a channel with short pin fins (pin length-to-diameter ratios of 0.5 and 1.0). The detailed distributions of the local endwall heat/mass-transfer coefficient were obtained for staggered and aligned arrays of pin fins, for the spanwise pin spacing-to-diameter ratio of 2.5, and for streamwise pin spacing-to-diameter ratios of 1.25 and 2.5. The Reynolds numbers were kept at about 33,000. Overall- and row-averaged Nusselt numbers compared very well with those from previous heat-transfer studies.
Cooling system having reduced mass pin fins for components in a gas turbine engine
Lee, Ching-Pang; Jiang, Nan; Marra, John J
2014-03-11
A cooling system having one or more pin fins with reduced mass for a gas turbine engine is disclosed. The cooling system may include one or more first surfaces defining at least a portion of the cooling system. The pin fin may extend from the surface defining the cooling system and may have a noncircular cross-section taken generally parallel to the surface and at least part of an outer surface of the cross-section forms at least a quartercircle. A downstream side of the pin fin may have a cavity to reduce mass, thereby creating a more efficient turbine airfoil.
NASA Astrophysics Data System (ADS)
Hua, Junye; Duan, Yuanyuan; Li, Gui; Xu, Qiong; Li, Dong; Wu, Wei; Zhao, Xiaobao; Qiu, Delai
2018-02-01
The experimental studies on heat transfer and flow resistance characteristics of ellipse-shape micro pin fin have been conducted which is drafted with hydrophobic material, holding the various contact angles fulfilled by adjusting the amount of Nano particle. The results show that with the increases of contact angle(83°,99.5°, 119.5°and 151.5°), the bottom wall temperature rises under the same flow rate. Under a certain heating condition with heating power as 100 W, the average convective heat transfer coefficient decreases with the increase of contact angle with the same Re. The value of Nu for ellipse-shape micro pin fin increases with a higher Re, with the maximum value under experimental condition of Nu as 25. Besides, the friction coefficient of micro pin fin experimental section drafted hydrophobicity treatment significantly decreases, compared with the smooth micro pin fin experimental section (θ = 83°). While the higher contact angle has obvious positive influences on friction coefficient under the same Re. Generally, the flow resistance performance of ellipse-shape micro pin fin drafted with hydrophobic material is better than that without any treatment.
Heat Transfer Measurements of Internally Finned Rotating Heat Pipes.
1983-12-01
42 C. RESULTS OF STRAIGHT 22 FIN CONDENSER o . o . 51 D. RESULTS OF HELICAL 14 AND 16 FIN CONDENSER o 51 E. RESULTS OF HELICAL 36 FIN...88 C.6 RESULTS OF STRAIGHT 22 FIN CONDENSER AT 2800 RPM . . . . . . . . . . . . . . . . . . . . 89 C.7 RESULTS OF HELICAL 16 FIN CONDENSER ...AT 700 RPM . 90 C.8 RESULTS OF HELICAL 16 PIN CONDENSER AT 1600 RPM . 91 C.9 RESULTS OF HELICAL 16 PIN CONDENSER AT 2800 RPM . 92 C. 10 RESULTS OF
NASA Astrophysics Data System (ADS)
Usman, Hazrat; Ali, Hafiz Muhammad; Arshad, Adeel; Ashraf, Muhammad Junaid; Khushnood, Shahab; Janjua, Muhammad Mansoor; Kazi, S. N.
2018-05-01
This experimental study determines and compares the thermal performance of unfinned and finned PCM based heat sinks. For the analysis considering pin-fins as thermal conductivity enhancer (TCE), triangular configuration is considered. It is further classified into inline and staggered pin-fin arrangements. Three popular variants of paraffin namely paraffin wax, RT-44 and RT-35HC are incorporated as phase change materials (PCMs) inside the heat sink. The volume fraction of pin-fins and PCMs are kept constant at 9% and 90% respectively. The heat input at the base of heat sinks ranges from 5 W to 8 W. The results are presented in two different cases, charging and discharging, and the analysis of temperature variation and comparison of fin arrangements in three different heat sinks with and without PCM. Further the enhancement ratios are determined to quantify the thermal performance in operation time of heat sink for passive cooling with the influence of PCMs and TCEs. The results suggest triangular inline pin-fin as the dominant heat sink geometry and RT-44 as the most efficient PCM for passive thermal management of electronic devices.
NASA Astrophysics Data System (ADS)
Duangthongsuk, Weerapun; Wongwises, Somchai
2018-05-01
In this study, a comparison of the convective heat transfer, pressure drop, and performance index characteristics of heat sinks with a miniature circular pin-fin inline arrangement (MCFHS) and a zigzag flow channel with single cross-cut structures (CCZ-HS) is presented. SiO2-water nanofluids with different particle concentrations are used as the coolant. The effects of the heat sink type, particle concentration and fluid flow rate on the thermal and hydraulic performances are evaluated. The testing conditions are performed at the wall heat fluxes of 10 to 60 kW/m2 and at a mass flow rate ranging from 0.18 to 0.6 kg/s. The dimension of heat sinks is equally designed at 28 × 33 mm. The heat transfer area of MCFHS and of CCZ-HS is 1430 and 1238 mm2, respectively. Similarly, the hydraulic diameter of the flow channel of MCFHS and of CCZ-HS is 1.2 and 1.0 mm, respectively. The measured data indicate that the cooling performances of CCZ-HS are about 24-55% greater than that of MCFHS. The effects of the channel diameter and single cross-cut of the flow channel are more dominant than the effects of the fin structure and heat transfer area.
Optimization of geometric parameters of heat exchange pipes pin finning
NASA Astrophysics Data System (ADS)
Akulov, K. A.; Golik, V. V.; Voronin, K. S.; Zakirzakov, A. G.
2018-05-01
The work is devoted to optimization of geometric parameters of the pin finning of heat-exchanging pipes. Pin fins were considered from the point of view of mechanics of a deformed solid body as overhang beams with a uniformly distributed load. It was found out under what geometric parameters of the nib (diameter and length); the stresses in it from the influence of the washer fluid will not exceed the yield strength of the material (aluminum). Optimal values of the geometric parameters of nibs were obtained for different velocities of the medium washed by them. As a flow medium, water and air were chosen, and the cross section of the nibs was round and square. Pin finning turned out to be more than 3 times more compact than circumferential finning, so its use makes it possible to increase the number of fins per meter of the heat-exchanging pipe. And it is well-known that this is the main method for increasing the heat transfer of a convective surface, giving them an indisputable advantage.
Fluid-cooled heat sink with improved fin areas and efficiencies for use in cooling various devices
Bharathan, Desikan; Bennion, Kevin; Kelly, Kenneth; Narumanchi, Sreekant
2015-04-21
The disclosure provides a fluid-cooled heat sink having a heat transfer base and a plurality of heat transfer fins in thermal communication with the heat transfer base, where the heat transfer base and the heat transfer fins form a central fluid channel through which a forced or free cooling fluid may flow. The heat transfer pins are arranged around the central fluid channel with a flow space provided between adjacent pins, allowing for some portion of the central fluid channel flow to divert through the flow space. The arrangement reduces the pressure drop of the flow through the fins, optimizes average heat transfer coefficients, reduces contact and fin-pin resistances, and reduces the physical footprint of the heat sink in an operating environment.
NASA Technical Reports Server (NTRS)
Olson, D. A.
1991-01-01
The heat transfer and pressure drop characteristics of a novel, compact heat exchanger in helium gas were measured at 3.5 MPa and Reynolds numbers of 450 to 12,000. The pin-fin specimen consisted of pins, 0.51 mm high and spaced 2.03 mm on centers, spanning a channel through which the helium flows; the angle of the row of pins to the flow direction was 18 deg. The specimen was radiatively heated on the top side at heat fluxes up to 74 W/sq cm and insulated on the back side. Correlations were developed for the friction factor and Nusselt number. The Nusselt number compares favorably to those of past studies of staggered pin-fins, when the measured temperatures are extrapolated to the temperature of the wall-fluid interface.
Fluid-cooled heat sink for use in cooling various devices
DOE Office of Scientific and Technical Information (OSTI.GOV)
Bharathan, Desikan; Bennion, Kevin; Kelly, Kenneth
The disclosure provides a fluid-cooled heat sink having a heat transfer base, a shroud, and a plurality of heat transfer fins in thermal communication with the heat transfer base and the shroud, where the heat transfer base, heat transfer fins, and the shroud form a central fluid channel through which a forced or free cooling fluid may flow. The heat transfer pins are arranged around the central fluid channel with a flow space provided between adjacent pins, allowing for some portion of the central fluid channel flow to divert through the flow space. The arrangement reduces the pressure drop ofmore » the flow through the fins, optimizes average heat transfer coefficients, reduces contact and fin-pin resistances, and reduces the physical footprint of the heat sink in an operating environment.« less
Effects of Pin Detached Space on Heat Transfer in a Rib Roughened Channel
DOE Office of Scientific and Technical Information (OSTI.GOV)
Siw, Sin Chien; Chyu, Minking K.; Alvin, Mary Anne
2012-11-08
An experimental study is performed to investigate the heat transfer characteristics and frictional losses in a rib roughened channel combined with detached pin-fins. The overall channel geometry (W=76.2 mm, E=25.4 mm) simulates an internal cooling passage of wide aspect ratio (3:1) in a gas turbine airfoil. With a given pin diameter, D=6.35 mm=[1/4]E, three different pin-fin height-to-diameter ratios, H/D=4, 3, and 2, were examined. Each of these three cases corresponds to a specific pin array geometry of detachment spacing (C) between the pin-tip and one of the endwalls, i.e., C/O=0, 1, 2, respectively. The rib height-to-channel height ratio is 0.0625.more » Two newly proposed cross ribs, namely the broken rib and full rib are evaluated in this effort. The broken ribs are positioned in between two consecutive rows of pin-fins, while the full ribs are fully extended adjacent to the pin-fins. The Reynolds number, based on the hydraulic diameter of the unobstructed cross section and the mean bulk velocity, ranges from 10,000 to 25,000. The experiment employs a hybrid technique based on transient liquid crystal imaging to obtain distributions of the local heat transfer coefficient over all of the participating surfaces, including the endwalls and all pin elements. The presence of ribs enhances local heat transfer coefficient on the endwall substantially by approximately 20% to 50% as compared to the neighboring endwall. In addition, affected by the rib geometry, which is a relatively low profile as compared to the overall height of the channel, the pressure loss seems to be insensitive to the presence of the ribs. However, from the overall heat transfer enhancement standpoint, the baseline cases (without ribs) outperform cases with broken ribs or full ribs.« less
Experimental Investigation on Heat Transfer Characteristics of Different Metallic Fin Arrays
NASA Astrophysics Data System (ADS)
Sangewar, Ravi Kumar
2018-04-01
The reliability of electronic equipment depends on the reliability of the system. For small applications natural convection cooling is sufficient, but for the electronic equipment having number of heat generating components, forced convection cooling is essential. In number of cases, pin fin arrangement is preferred for augmentation of heat transfer. Here, the performance of pin fin array of copper and aluminum material with in-line, as well as staggered arrangement over a flat plate is studied. Constant heat input was given to the inline, staggered arrangement of copper as well as aluminium pin fin arrays. In the present experimental study, heat input and airflow rates are the variables. It was found that the heat transfer coefficient for staggered array is 15% more than that of the in-line array, at the same time pressure drop across the staggered array is more by 10% than the in-line array. The pressure drop was observed to be increasing with increase in flow rate as expected. Endeavor of the present work is to find the optimum spacing between the fins in an array for maximum heat transfer rate, by investigating the heat transfer characteristics.
Effects of Pin Detached Space on Heat Transfer and Pin-Fin Arrays
DOE Office of Scientific and Technical Information (OSTI.GOV)
Siw, Sin Chien; Chyu, Minking K.; Shih, Tom I. -P.
2012-01-01
Heat transfer and pressure characteristics in a rectangular channel with pin-fin arrays of partial detachment from one of the endwalls have been experimentally studied. The overall channel geometry (W=76.2 mm, E=25.4 mm) simulates an internal cooling passage of wide aspect ratio (3:1) in a gas turbine airfoil. With a given pin diameter, D=6.35 mm=¼E, three different pin-fin height-to-diameter ratios, H/D=4, 3, and 2, were examined. Each of these three cases corresponds to a specific pin array geometry of detachment spacing (C) between the pin tip and one of the endwalls, i.e., C/D=0, 1, 2, respectively. The Reynolds number, based onmore » the hydraulic diameter of the unobstructed cross-section and the mean bulk velocity, ranges from 10,000 to 25,000. The experiment employs a hybrid technique based on transient liquid crystal imaging to obtain the distributions of the local heat transfer coefficient over all of the participating surfaces, including the endwalls and all the pin elements. Experimental results reveal that the presence of a detached space between the pin tip and the endwall has a significant effect on the convective heat transfer and pressure loss in the channel. The presence of pin-to-endwall spacing promotes wall-flow interaction, generates additional separated shear layers, and augments turbulent transport. In general, an increase in detached spacing, or C/D, leads to lower heat transfer enhancement and pressure drop. However, C/D=1, i.e., H/D=3, of a staggered array configuration exhibits the highest heat transfer enhancement, followed by the cases of C/D=0 and C/D=2, i.e., H/D=4 or 2, respectively.« less
Fin-line PIN-diode attenuators and switches for 94 GHz range
NASA Astrophysics Data System (ADS)
Meinel, H.; Callsen, H.
1982-06-01
The letter reports new results of fin-line PIN-diode attenuators and switches for the 94 GHz range. Design and performance of SPST and SPDT switches - single pole single throw and single pole double throw, respectively - will be presented. The attenuation of the SPST switch, for example, can be adjusted between 2 and 35 dB over the entire waveguide band from 75 to 110 GHz.
Cup waveguide antenna with integrated polarizer and OMT
NASA Technical Reports Server (NTRS)
Kory, Carol (Inventor); Acosta, Roberto J. (Inventor); Lambert, Kevin M. (Inventor)
2011-01-01
A cup waveguide antenna with integrated polarizer and OMT for simultaneously communicating left and right hand circularly polarized electromagnetic waves is adjustable to obtain efficient propagation and reception of electromagnetic waves. The antenna includes a circular waveguide having an orthomode transducer utilizing first and second pins longitudinally spaced apart and oriented orthogonally with respect to each other. Six radially-oriented adjustable polarizer screws extend from the exterior to the interior of the waveguide. A septum intermediate the first and second pins is aligned with the first pin. Adjustment of the polarizer screws enables maximized propagation of and/or response to left hand circularly polarized electromagnetic waves by the first pin while simultaneously enabling maximized propagation of and/or response to right hand circularly polarized electromagnetic waves by the second pin.
2017-10-19
consequently, important to obtain relevant experimental data for such short, pin fin channels before finalizing the design of the LN2 microcooler. In the next...must be taken in designing the LD micro pin-fin cooler to reflect these experimental trends. Figure 8: Base Heat Transfer Coefficient vs... Experimental Hybrid Approach Based on Spectral Power Distribution for Quantitative Degradation Analysis of Phosphor Converted LED," Ieee Transactions on
NASA Astrophysics Data System (ADS)
Maldonado, Jaime J.
1994-04-01
Hypersonic vehicles are exposed to extreme thermal conditions compared to subsonic aircraft; therefore, some level of thermal management is required to protect the materials used. Normally, hypersonic vehicles experience the highest temperatures in the nozzle throat, and aircraft and propulsion system leading edges. Convective heat transfer augmentation techniques can be used in the thermal management system to increase heat transfer of the cooling channels in those areas. The techniques studied in this report are pin-fin, offset-fin, ribbed and straight roughened channel. A smooth straight channel is used as the baseline for comparing the techniques. SINDA '85, a lumped parameter finite difference thermal analyzer, is used to model the channels. Subroutines are added to model the fluid flow assuming steady one dimensional compressible flow with heat addition and friction. Correlations for convective heat transfer and friction are used in conjunction with the fluid flow analysis mentioned. As expected, the pin-fin arrangement has the highest heat transfer coefficient and the largest pressure drop. All the other devices fall in between the pin-fin and smooth straight channel. The selection of the best heat augmentation method depends on the design requirements. A good approach may be a channel using a combination of the techniques. For instance, several rows of pin-fins may be located at the region of highest heat flux, surrounded by some of the other techniques. Thus, the heat transfer coefficient is maximized at the region of highest heat flux while the pressure drop is not excessive.
NASA Technical Reports Server (NTRS)
Maldonado, Jaime J.
1994-01-01
Hypersonic vehicles are exposed to extreme thermal conditions compared to subsonic aircraft; therefore, some level of thermal management is required to protect the materials used. Normally, hypersonic vehicles experience the highest temperatures in the nozzle throat, and aircraft and propulsion system leading edges. Convective heat transfer augmentation techniques can be used in the thermal management system to increase heat transfer of the cooling channels in those areas. The techniques studied in this report are pin-fin, offset-fin, ribbed and straight roughened channel. A smooth straight channel is used as the baseline for comparing the techniques. SINDA '85, a lumped parameter finite difference thermal analyzer, is used to model the channels. Subroutines are added to model the fluid flow assuming steady one dimensional compressible flow with heat addition and friction. Correlations for convective heat transfer and friction are used in conjunction with the fluid flow analysis mentioned. As expected, the pin-fin arrangement has the highest heat transfer coefficient and the largest pressure drop. All the other devices fall in between the pin-fin and smooth straight channel. The selection of the best heat augmentation method depends on the design requirements. A good approach may be a channel using a combination of the techniques. For instance, several rows of pin-fins may be located at the region of highest heat flux, surrounded by some of the other techniques. Thus, the heat transfer coefficient is maximized at the region of highest heat flux while the pressure drop is not excessive.
Pin fin compliant heat sink with enhanced flexibility
Schultz, Mark D.
2018-04-10
Heat sinks and methods of using the same include a top and bottom plate, at least one of which has a plurality of pin contacts flexibly connected to one another, where the plurality of pin contacts have vertical and lateral flexibility with respect to one another; and pin slice layers, each having multiple pin slices, arranged vertically between the top and bottom plates such that the plurality of pin slices form substantially vertical pins connecting the top and bottom plates.
Copper vertical micro dendrite fin arrays and their superior boiling heat transfer capability
NASA Astrophysics Data System (ADS)
Wang, Ya-Qiao; Lyu, Shu-Shen; Luo, Jia-Li; Luo, Zhi-Yong; Fu, Yuan-Xiang; Heng, Yi; Zhang, Jian-Hui; Mo, Dong-Chuan
2017-11-01
Micro pin fin arrays have been widely used in electronic cooling, micro reactors, catalyst support, and wettability modification and so on, and a facile way to produce better micro pin fin arrays is demanded. Herein, a simple electrochemical method has been developed to fabricate copper vertical micro dendrite fin arrays (Cu-VMDFA) with controllable shapes, number density and height. High copper sulphate concentration is one key point to make the dendrite stand vertically. Besides, the applied current should rise at an appropriate rate to ensure the copper dendrite can grow vertically on its own. The Cu-VMDFA can significantly enhance the heat transfer coefficient by approximately twice compared to the plain copper surface. The Cu-VMDFA may be widely used in boiling heat transfer areas such as nuclear power plants, electronic cooling, heat exchangers, and so on.
NASA Astrophysics Data System (ADS)
Ahmadi Nadooshan, Afshin; Kalbasi, Rasool; Afrand, Masoud
2018-04-01
Perforated fins effects on the heat transfer rate of a circular tube are examined experimentally. An experimental system is set up through the wind tunnel and equipped with necessary measurement tools. Hot water passes through the finned tube and heat transfers to the fin-side air created using the wind tunnel with different velocities. Two fin sets of identical weight are installed on a circular tube with different outer diameters of 22 and 26 mm. The experiments are conducted at two different mass flow rates of the hot water and six Reynolds number of external air flow. Considering the four finned tubes and one no finned tube, a total of 60 tests are conducted. Results showed that with increasing the internal or external flow rates, the effect of larger cross-sectional area is greater. By opening holes on the fins, in addition to weight loss, the maximum heat transfer rate for perforated fins increases by 8.78% and 9.23% respectively for mass flow rates of 0.05 and 0.1 kg/s at low external Reynolds number. While, at high external Reynolds number, the holes reduces heat transfer by 8.4% and 10.6% for mass flow rates of 0.05 and 0.1 kg/s, respectively.
Experimental Modal Analysis of Rectangular and Circular Beams
ERIC Educational Resources Information Center
Emory, Benjamin H.; Zhu, Wei Dong
2006-01-01
Analytical and experimental methods are used to determine the natural frequencies and mode shapes of Aluminum 6061-T651 beams with rectangular and circular cross-sections. A unique test stand is developed to provide the rectangular beam with different boundary conditions including clamped-free, clamped-clamped, clamped-pinned, and pinned-pinned.…
Vortex Shedding from Finned Circular Cylinders
1980-11-01
FINNED CIRCULAR CYLINDERSo ,rm"" 1..UTNOI .)R*., r. *.040, 111SPOR- / T NuMBII f.John G. elute asOHans J.’/, ugt -. . . , ,<-. -. ,:. =., .. Siil P3RPIO...fins and other sharp protuberances. These purely two-dimensional flows then may be used in a strip theory to include at least some aspects of three...boundary- layer theory . Such a prediction method, together with a technique to provide for a vortex sheet at the separation point, will be included in
2015-08-01
Forced Convective Heat Transfer Across a Pin Fin Micro Heat Sink”, International Journal of Heat and Mass Transfer 48 (2005) 3615-3627. 3. Cao...from Pin Fins Situated in an Oncoming Longitudinal Flow Which Turns to Crossflow”, International Journal of Heat and Mass Transfer, Vol. 25 No. 5...Flow Forced Convection”, International Journal of Heat and Mass Transfer, Vol. 39, No. 2, pp. 311-317, 1996. 11. Khan, W., Culham, J., and Yovanovich
Rock, H.R.
1963-12-24
A composite control rod for use in controlling a nuclear reactor is described. The control rod is of sandwich construction in which finned dowel pins are utilized to hold together sheets of the neutron absorbing material and nonabsorbing structural material thereby eliminating the need for being dependent on the absorbing material for structural support. The dowel pins perform the function of absorbing the forces due to differential thermal expansion, seating further with the fins into the sheets of material and crushing before damage is done either to the absorbing or non-absorbing material. (AEC)
Propagation of spiral waves pinned to circular and rectangular obstacles.
Sutthiopad, Malee; Luengviriya, Jiraporn; Porjai, Porramain; Phantu, Metinee; Kanchanawarin, Jarin; Müller, Stefan C; Luengviriya, Chaiya
2015-05-01
We present an investigation of spiral waves pinned to circular and rectangular obstacles with different circumferences in both thin layers of the Belousov-Zhabotinsky reaction and numerical simulations with the Oregonator model. For circular objects, the area always increases with the circumference. In contrast, we varied the circumference of rectangles with equal areas by adjusting their width w and height h. For both obstacle forms, the propagating parameters (i.e., wavelength, wave period, and velocity of pinned spiral waves) increase with the circumference, regardless of the obstacle area. Despite these common features of the parameters, the forms of pinned spiral waves depend on the obstacle shapes. The structures of spiral waves pinned to circles as well as rectangles with the ratio w/h∼1 are similar to Archimedean spirals. When w/h increases, deformations of the spiral shapes are observed. For extremely thin rectangles with w/h≫1, these shapes can be constructed by employing semicircles with different radii which relate to the obstacle width and the core diameter of free spirals.
NASA Technical Reports Server (NTRS)
House, Rufus O; Wallace, Arthur R
1941-01-01
Report presents the results of a wind-tunnel investigation of the effect of wing-fuselage interference on lateral-stability characteristics made in the NACA 7 by 10-foot wind tunnel on four fuselages and two fins, representing high-wing, low-wing, and midwing monoplanes. The fuselages are of circular and elliptical cross section. The wings have rounded tips and, in plan form, one is rectangular and the three are tapered 3:1 with various amounts of sweep. The rate of change in the coefficients of rolling moment, yawing moment, and lateral force with angle of yaw is given in a form to show the increment caused by wing-fuselage interference for the model with no fin and the effect of wing-fuselage interference on fin effectiveness. Results for the fuselage-fin combination and the wing tested alone are also given.
Subsonic Aerodynamic Characteristics of a Circular Body Earth-to-Orbit Vehicle
NASA Technical Reports Server (NTRS)
Lepsch, Roger A., Jr.; Ware, George M.; MacConochie, Ian O.
1996-01-01
A test of a generic reusable earth-to-orbit transport was conducted in the 7- by 10-Foot high-speed tunnel at the Langley Research Center at Mach number 0.3. The model had a body with a circular cross section and a thick clipped delta wing as the major lifting surface. For directional control, three different vertical fin arrangements were investigated: a conventional aft-mounted center vertical fin, wingtip fins, and a nose-mounted vertical fin. The configuration was longitudinally stable about the estimated center-of-gravity position of 0.72 body length and had sufficient pitch-control authority for stable trim over a wide range of angle of attack, regardless of fin arrangement. The maximum trimmed lift/drag ratio for the aft center-fin configuration was less than 5, whereas the other configurations had values of above 6. The aft center-fin configuration was directionally stable for all angles of attack tested. The wingtip and nose fins were not intended to produce directional stability but to be active controllers for artificial stabilization. Small rolling-moment values resulted from yaw control of the nose fin. Large adverse rolling-moment increments resulted from tip-fin controller deflection above 13 deg angle of attack. Flow visualization indicated that the adverse rolling-moment increments were probably caused by the influence of the deflected tip-fin controller on wing flow separation.
Wind Tunnel Investigation of Fuselage Stability in Yaw with Various Arrangements of Fins
NASA Technical Reports Server (NTRS)
Hoggard, H Page, Jr
1940-01-01
An investigation was made in the 7-by-10 foot wind tunnel to determine the effects of dorsal-type fins and various arrangements of fins on the aerodynamic characteristics of a streamline circular fuselage. Comparative plots of the aerodynamic characteristics of the fuselage alone and the fuselage with various fin arrangements are given to show their effects on coefficients of yawing moment, drag, and lateral force. Results are also given for one case in which a rear fin on a circular fuselage was faired with modeling clay to obtain a fuselage shape with the same side elevation as the fuselage with the unfaired fin but with an elliptical cross section over the rearward portion of the fuselage. The results indicated that fin area to the rear of the center of gravity of the fuselage was beneficial in reducing the magnitude of the unstable yawing moments at large angles of yaw; whereas, fin area forward of the center of gravity was harmful. The dorsal-type fin was more effective for increasing the yawing stability of the fuselage than was a smoothly faired rearward portion with the same side elevation as the fuselage with the unfaired dorsal type fin. The minimum drag coefficient and the slope of the curve of yawing-moment coefficient of the fuselage at zero yaw were unaffected by the addition of the fins, within the experimental accuracy of the tests.
NASA Technical Reports Server (NTRS)
Blair, A. B., Jr.
1990-01-01
Wind tunnel tests were conducted on monoplanar circular missile configurations with low-profile quadriform tail fins to provide an aerodynamic data base to study and evaluate air-launched missile candidates for efficient conformal carriage on supersonic-cruise-type aircraft. The tests were conducted at Mach numbers from 1.70 to 2.86 for a constant Reynolds number per foot of 2,000,000. Selected test results are presented to show the effects of tail-fin dihedral angle, wing longitudinal and vertical location, and nose-body strakes on the static longitudinal and lateral-directional aerodynamic stability and control characteristics.
Impact of Cubic Pin Finned Surface Structure Geometry upon Spray Cooling Heat Transfer
NASA Technical Reports Server (NTRS)
Silk, Eric A.; Kim, Jungho; Kiger, Ken
2005-01-01
Experiments were conducted to study the effects of enhanced surface structures on heat flux using spray cooling. The surface enhancements consisted of cubic pin fins machined on the top surface of copper heater blocks. The structure height, pitch, and width were parametrically vaned. Each copper block had a projected cross-sectional area of 2.0 sq cm. Measurements were also obtained on a heater block with a flat surface for baseline comparison purposes. A 2 x 2 nozzle array was used with PF-5060 as the working fluid. Thermal performance data were obtained under nominally degassed (chamber pressure of 41.4 kPa) and gassy conditions (chamber with N2 gas at 100.7 kPa) with a bulk fluid temperature of 20.5 C. Results for both the degassed and gassy cases show that structure width and separation distance have a dominant effect upon the heat transfer for the size ranges used. Cubic pin fin height had little impact upon heat flux. The maximum critical heat flux (CHF) attained for any of the surfaces was 121 W/sq cm, giving an enhancement of 51% relative to the flat surface case under nominally degassed conditions. The gassy case had a maximum CHF of 149 W/sq cm, giving an enhancement of 38% relative to the flat surface case.
Heat Transfer Enhancement for Finned-tube Heat Exchangers with Winglets
DOE Office of Scientific and Technical Information (OSTI.GOV)
O'Brien, James Edward; Sohal, Manohar Singh
2000-11-01
This paper presents the results of an experimental study of forced convection heat transfer in a narrow rectangular duct fitted with a circular tube and/or a delta-winglet pair. The duct was designed to simulate a single passage in a fin-tube heat exchanger. Heat transfer measurements were obtained using a transient technique in which a heated airflow is suddenly introduced to the test section. High-resolution local fin-surface temperature distributions were obtained at several times after initiation of the transient using an imaging infrared camera. Corresponding local fin-surface heat transfer coefficient distributions were then calculated from a locally applied one-dimensional semi-infinite inversemore » heat conduction model. Heat transfer results were obtained over an airflow rate ranging from 1.51 x 10-3 to 14.0 x 10-3 kg/s. These flow rates correspond to a duct-height Reynolds number range of 670 – 6300 with a duct height of 1.106 cm and a duct width-toheight ratio, W/H, of 11.25. The test cylinder was sized such that the diameter-to-duct height ratio, D/H is 5. Results presented in this paper reveal visual and quantitative details of local fin-surface heat transfer distributions in the vicinity of a circular tube, a delta-winglet pair, and a combination of a circular tube and a delta-winglet pair. Comparisons of local and average heat transfer distributions for the circular tube with and without winglets are provided. Overall mean finsurface Nusselt-number results indicate a significant level of heat transfer enhancement associated with the deployment of the winglets with the circular cylinder. At the lowest Reynolds numbers (which correspond to the laminar operating conditions of existing geothermal air-cooled condensers), the enhancement level is nearly a factor of two. At higher Reynolds numbers, the enhancement level is close to 50%.« less
Microstructure and Mechanical Performance of Friction Stir Spot-Welded Aluminum-5754 Sheets
NASA Astrophysics Data System (ADS)
Pathak, N.; Bandyopadhyay, K.; Sarangi, M.; Panda, Sushanta Kumar
2013-01-01
Friction stir spot welding (FSSW) is a recent trend of joining light-weight sheet metals while fabricating automotive and aerospace body components. For the successful application of this solid-state welding process, it is imperative to have a thorough understanding of the weld microstructure, mechanical performance, and failure mechanism. In the present study, FSSW of aluminum-5754 sheet metal was tried using tools with circular and tapered pin considering different tool rotational speeds, plunge depths, and dwell times. The effects of tool design and process parameters on temperature distribution near the sheet-tool interface, weld microstructure, weld strength, and failure modes were studied. It was found that the peak temperature was higher while welding with a tool having circular pin compared to tapered pin, leading to a bigger dynamic recrystallized stir zone (SZ) with a hook tip bending towards the upper sheet and away from the keyhole. Hence, higher lap shear separation load was observed in the welds made from circular pin compared to those made from tapered pin. Due to influence of size and hardness of SZ on crack propagation, three different failure modes of weld nugget were observed through optical cross-sectional micrograph and SEM fractographs.
Supersonic aerodynamic characteristics of a circular body Earth-to-Orbit vehicle
NASA Technical Reports Server (NTRS)
Ware, George M.; Engelund, Walter C.; Macconochie, Ian O.
1994-01-01
The circular body configuration is a generic single- or multi-stage reusable Earth-to-orbit transport. A thick clipped-delta wing is the major lifting surface. For directional control, three different vertical fin arrangements were investigated: a conventional aft-mounted center fin, wingtip fins, and a nose-mounted fin. The tests were conducted in the Langley Unitary Plan Wind Tunnel. The configuration is longitudinally stable about the estimated center of gravity of 0.72 body length up to a Mach number of about 3.0. Above Mach 3.0, the model is longitudinally unstable at low angles of attack but has a stable secondary trim point at angles of attack above 30 deg. The model has sufficient pitch control authority with elevator and body flap to produce stable trim over the test range. The model with the center fin is directionally stable at low angles of attack up to a Mach number of 3.90. The rudder-like surfaces on the tip fins and the all-movable nose fin are designed as active controls to produce artificial directional stability and are effective in producing yawing moment. The wing trailing-edge aileron surfaces are effective in producing rolling moment, but they also produce large adverse yawing moment.
Reindel, John
1990-01-01
A fin line circuit card containing a fin line slot feeds a dipole antenna ich extends a quarterwave outside the waveguide and provides an energy beam focal point at or near the open end of the waveguide. The dipole antenna thus maintains a wide and nearly constant beamwidth, low VSWR and a circular symmetric radiation pattern for use in electronic warfare direction finding and surveillance applications.
NASA Astrophysics Data System (ADS)
Pardeshi, Irsha
Efficient and effective cooling of the trailing edges of gas-turbine vanes and blades is challenging because there is very little space to work with. In this study, CFD simulations based on steady RANS closed by the shear-stress transport turbulence model were performed to study the flow and heat transfer in an L-shaped duct for the trailing edge under two operating conditions. One operating condition, referred to as the laboratory condition, where experimental measurements were made, has a Reynolds number at the duct inlet of ReD = 15,000, coolant inlet temperature of Tinlet = 300 K, wall temperature of Twall = 335 K, a back pressure of Pb = 1 atm. When rotating, the angular speed was O = 1,000 rpm. The other condition, referred to as the engine-relevant condition, has Re D = 150,000 at the duct inlet, Tinlet = 673 K, Twall = 1,173 K, and Pb = 25 atm. When rotating, O was 3,600 rpm. The objective is to understand the nature of the flow and heat transfer in an L-shaped cooling passage for the trailing edge that has a combination of ribs and pin fins under rotating and non-rotating conditions with focus on how pin fins and ribs distribute the flow throughout the passage and to understand what features of the flow and heat transfer can or cannot be extrapolated from the laboratory to the engine-relevant operating conditions. When there is no rotation, results obtained show that for both operating conditions, the pin fins minimized the size of the separation bubble when the flow exits the inlet duct into the expanded portion of the L-shaped duct. The size of the separation bubble at the tip of the L-shaped duct created by the adverse pressure gradient is quite large for the laboratory condition and relatively small for the engine condition. Each rib was found to create two sets of recirculating flows, one just upstream of the rib because of the adverse pressure gradient induced by the rib and one just downstream of the rib because of flow separation from a sharp edge. These recirculating flows spiral from the ribs towards the exit of the L-shaped duct, and the spiraling brings cool fluid from the middle of the passage to the walls. Each pin fin was found to induce a pair of counter-rotating separated regions behind it and has horse-shoe vortices that wrap around it next to the top and bottom walls. The heat transfer is highest just upstream of the each rib, around the pin fins, and when the cooling fluid impinges on walls, and very low in the separated region next to the tip. When there is rotation, Coriolis force creates a pair of counter-rotating vortices that bring the cooler fluid to the trailing wall in the inlet duct. Thus, the trailing wall has higher heat transfer than the leading wall. In the inlet duct, centrifugal buoyancy causes a massive flow separation on the leading wall. In the expanded portion of the L-shaped duct, the centrifugal-buoyancy-induced separation on the leading wall is limited to the region with the ribs, and the separation degenerates into a series of smaller spiraling separation bubbles, one between every set of consecutive ribs. On the leading and trailing walls, the ribs and the pin fins induce the same kind of flows as they did under non-rotating conditions. Because of centrifugal-buoyancy-induced flow separation on the leading face, the heat transfer on the leading wall is 10-15% lower than that on the trailing wall, which is not significant. The adverse effects of centrifugal buoyancy were mitigated because the separation bubbles between the ribs are spiraling from the side wall to the trailing-edge exit and are constantly supplied by new coolant. The heat transfer on the side and back walls is higher near the trailing wall because centrifugal buoyancy directed most of the coolant flow towards the trailing wall. The size of the separation bubble at the tip of the L-shaped duct essentially disappeared when there is rotation for both the lab and engine-relevant conditions.
NASA Technical Reports Server (NTRS)
Damerow, W. P.; Murtaugh, J. P.; Burggraf, F.
1972-01-01
The flow characteristics of turbine airfoil cooling system components were experimentally investigated. Flow models representative of leading edge impingement, impingement with crossflow (midchord cooling), pin fins, feeder supply tube, and a composite model of a complete airfoil flow system were tested. Test conditions were set by varying pressure level to cover the Mach number and Reynolds number range of interest in advanced turbine applications. Selected geometrical variations were studied on each component model to determine these effects. Results of these tests were correlated and compared with data available in the literature. Orifice flow was correlated in terms of discharge coefficients. For the leading edge model this was found to be a weak function of hole Mach number and orifice-to-impinged wall spacing. In the impingement with crossflow tests, the discharge coefficient was found to be constant and thus independent of orifice Mach number, Reynolds number, crossflow rate, and impingement geometry. Crossflow channel pressure drop showed reasonable agreement with a simple one-dimensional momentum balance. Feeder tube orifice discharge coefficients correlated as a function of orifice Mach number and the ratio of the orifice-to-approach velocity heads. Pin fin data was correlated in terms of equivalent friction factor, which was found to be a function of Reynolds number and pin spacing but independent of pin height in the range tested.
Two-Phase Flow in Microchannels with Non-Circular Cross Section
NASA Astrophysics Data System (ADS)
Eckett, Chris A.; Strumpf, Hal J.
2002-11-01
Two-phase flow in microchannels is of practical importance in several microgravity space technology applications. These include evaporative and condensing heat exchangers for thermal management systems and vapor cycle systems, phase separators, and bioreactors. The flow passages in these devices typically have a rectangular cross-section or some other non-circular cross-section; may include complex flow paths with branches, merges and bends; and may involve channel walls of different wettability. However, previous experimental and analytical investigations of two-phase flow in reduced gravity have focussed on straight, circular tubes. This study is an effort to determine two-phase flow behavior, both with and without heat transfer, in microchannel configurations other than straight, circular tubes. The goals are to investigate the geometrical effects on flow pattern, pressure drop and liquid holdup, as well as to determine the relative importance of capillary, surface tension, inertial, and gravitational forces in such geometries. An evaporative heat exchanger for microgravity thermal management systems has been selected as the target technology in this investigation. Although such a heat exchanger has never been developed at Honeywell, a preliminary sizing has been performed based on knowledge of such devices in normal gravity environments. Fin shapes considered include plain rectangular, offset rectangular, and wavy fin configurations. Each of these fin passages represents a microchannel of non-circular cross section. The pans at the inlet and outlet of the heat exchanger are flow branches and merges, with up to 90-deg bends. R-134a has been used as the refrigerant fluid, although ammonia may well be used in the eventual application.
Mechanism of tonal noise generation from circular cylinder with spiral fin
NASA Astrophysics Data System (ADS)
Yamashita, Ryo; Hayashi, Hidechito; Okumura, Tetsuya; Hamakawa, Hiromitsu
2014-12-01
The pitch of the spiral finned tube influences seriously to the acoustic resonance in the heat exchanger. In this research, the flow characteristics in relating to the aeolian tone from the finned cylinder are studied by the numerical simulation. It is observed that the tonal noise generated from the finned tube at two pitch spaces. The ratio of the fin pitch to the cylinder diameter is changed at 0.11 and 0.27. The tone level increases and the frequency decreases with the pitch shorter. The separation flow from the cylinder generates the span-wise vortices, Karman vortices, and the separation flow from the fin generates the stream-wise vortices. When the fin pitch ratio is small, the stream-wise vortices line up to span-wise and become weak rapidly. Only the Karman vortices are remained and integrate in span. So the Karman vortex became large. This causes the low frequency and the large aeolian tone.
Flame-spreading phenomena in the fin-slot region of a solid rocket motor
NASA Astrophysics Data System (ADS)
Kuo, K. K.; Kokal, R. A.; Paulauskas, M.; Alaksin, P.; Lee, L. S.
1993-06-01
Flame-spreading processes in the fin-slot regions of solid-propellant motor grains have the potential to influence the behavior of the overall ignition transient. The work being done on this project is aimed at obtaining a better understanding of the flame-spreading processes in rocket motors with aft-end fin slots. Non-intrusive optical diagnostic methods were employed to acquire flame-spreading measurements in the fin-slot region of a subscale rocket motor. Highly non-uniform flame-spreading processes were observed in both the deep and shallow fin regions of the test rig. The average flame-spreading rates in the fin-slot region were found to be two orders of magnitude less than those in the circular port region of a typical rocket motor. The flame-spreading interval was found to correlate well with the local pressurization rates. A higher pressurization rate produces a shorter flame-spreading time interval.
Local Heat Transfer for Finned-Tube Heat Exchangers using Oval Tubes
DOE Office of Scientific and Technical Information (OSTI.GOV)
O'Brien, James Edward; Sohal, Manohar Singh
2000-08-01
This paper presents the results of an experimental study of forced convection heat transfer in a narrow rectangular duct fitted with either a circular tube or an elliptical tube in crossflow. The duct was designed to simulate a single passage in a fin-tube heat exchanger. Heat transfer measurements were obtained using a transient technique in which a heated airflow is suddenly introduced to the test section. High-resolution local fin-surface temperature distributions were obtained at several times after initiation of the transient using an imaging infrared camera. Corresponding local fin-surface heat transfer coefficient distributions were then calculated from a locally appliedmore » one-dimensional semi-infinite inverse heat conduction model. Heat transfer results were obtained over an airflow rate ranging from 1.56 x 10-3 to 15.6 x 10-3 kg/s. These flow rates correspond to a duct-height Reynolds number range of 630 – 6300 with a duct height of 1.106 cm and a duct width-toheight ratio, W/H, of 11.25. The test cylinder was sized such that the diameter-to-duct height ratio, D/H is 5. The elliptical tube had an aspect ratio of 3:1 and a/H equal to 4.33. Results presented in this paper reveal visual and quantitative details of local fin-surface heat transfer distributions in the vicinity of circular and oval tubes and their relationship to the complex horseshoe vortex system that forms in the flow stagnation region. Fin surface stagnation-region Nusselt numbers are shown to be proportional to the square-root of Reynolds number.« less
Running Performance of a Pinning-Type Superconducting Magnetic Levitation Guide
NASA Astrophysics Data System (ADS)
Okano, M.; Iwamoto, T.; Furuse, M.; Fuchino, S.; Ishii, I.
2006-06-01
A pinning-type superconducting magnetic levitation guide with bulk high-Tc superconductors was studied for use as a goods transportation system, an energy storage system, etc. A superconducting magnetic levitation running test apparatus with a circular track of ca. 38 m length, 12 m diameter, which comprises the magnetic rail constituted by Nd-B-Fe rare-earth permanent magnets and steel plates, was manufactured to examine loss and high-speed performance of the magnetic levitation guide. Running tests were conducted in air. These tests clarify that a vehicle supported by a superconducting magnetic levitation guide runs stably at speeds greater than 42 km/h above the circular track.
Saikko, Vesa
2015-01-21
The temporal change of the direction of sliding relative to the ultrahigh molecular weight polyethylene (UHMWPE) component of prosthetic joints is known to be of crucial importance with respect to wear. One complete revolution of the resultant friction vector is commonly called a wear cycle. It was hypothesized that in order to accelerate the wear test, the cycle frequency may be substantially increased if the circumference of the slide track is reduced in proportion, and still the wear mechanisms remain realistic and no overheating takes place. This requires an additional slow motion mechanism with which the lubrication of the contact is maintained and wear particles are conveyed away from the contact. A three-station, dual motion high frequency circular translation pin-on-disk (HF-CTPOD) device with a relative cycle frequency of 25.3 Hz and an average sliding velocity of 27.4 mm/s was designed. The pins circularly translated at high frequency (1.0 mm per cycle, 24.8 Hz, clockwise), and the disks at low frequency (31.4mm per cycle, 0.5 Hz, counter-clockwise). In a 22 million cycle (10 day) test, the wear rate of conventional gamma-sterilized UHMWPE pins against polished CoCr disks in diluted serum was 1.8 mg per 24 h, which was six times higher than that in the established 1 Hz CTPOD device. The wear mechanisms were similar. Burnishing of the pin was the predominant feature. No overheating took place. With the dual motion HF-CTPOD method, the wear testing of UHMWPE as a bearing material in total hip arthroplasty can be substantially accelerated without concerns of the validity of the wear simulation. Copyright © 2014 Elsevier Ltd. All rights reserved.
Altitude-Limiting Airbrake System for Small to Medium Scale Rockets
NASA Technical Reports Server (NTRS)
Aaron, Robert F., III
2013-01-01
The goal of the overall internship opportunity this semester was to learn and practice the elements of engineering design through direct exposure to real engineering problems. The primary exposure was to design and manufacture an airbrake device for use with small-medium scale rocket applications. The idea was to take the presented concept of a solution and transform said concept into a reliable fully-functioning and reusable mechanism. The mechanism was to be designed as an insurance feature so that the overall altitude of a rocket with relatively undetermined engine capabilities does not unexpectedly exceed the imposed 10,000 foot ceiling, per range requirements. The airbrake concept was introduced to the Prototype Development Lab as a rotation-driven four tiered offset track pin mechanism, i.e. the airbrake was deployed by rotating a central shaft attached directly to the bottom plate. The individual airbrake fins were subsequently deployed using multiple plates with tracks of offset curvature. The fins were created with guide pins to follow the tracks in each of the offset plates, thus allowing the simultaneous rotational deployment of all fins by only rotating one plate. The concept of this solution was great; though it did not function in application. The rotating plates alone brought up problems like the entire back half of the rocket rotating according to the motion of the aforementioned base plate. Subsequently, the solution currently under development became a static linear actuator-driven spring-loaded fin release system. This solution is almost instantaneously triggered electronically when the avionics detect that the rocket has reached the calculated altitude of deceleration. This altitude will allow enough time remaining to the overall ceiling to adequately decelerate the rocket prior to reaching the ceiling.
NASA Astrophysics Data System (ADS)
Shoukat, Ahmad Adnan; Shaban, Muhammad; Israr, Asif; Shah, Owaisur Rahman; Khan, Muhammad Zubair; Anwar, Muhammad
2018-03-01
We investigate the heat transfer effect of different types of Nano-fluids on the pin fin heat sinks used in computer's microprocessor. Nano-particles of Aluminum oxide have been used with volumetric concentrations of 0.002% and Silver oxide with volumetric concentrations of 0.001% in the base fluid of deionized water. We have also used Aluminum oxide with ethylene glycol at volumetric concentrations of 0.002%. We report the cooling rates of Nano-fluids for pin-fin heat to cool the microprocessor and compare these with the cooling rate of pure water. We use a microprocessor heat generator in this investigation. The base temperature is obtained using surface heater of power 130 W. The main purpose of this work is to minimize the base temperature, and increase the heat transfer rate of the water block and radiator. The temperature of the heat sink is maintained at 110 °C which is nearly equal to the observed computer microprocessor temperature. We also provide the base temperature at different Reynolds's number using the above mention Nano-fluids with different volumetric concentrations.
Wojcik, Thaddeus A.
1978-01-01
Two abutting members are locked together by reaming a hole entirely through one member and at least partly through the other, machining a circular groove in each through hole just below the surface of the member, press fitting a dowel pin having a thin wall extension on at least one end thereof into the hole in both members, a thin wall extension extending into each through hole, crimping or snapping the thin wall extension into the grooves to positively lock the dowel pin in place and, if necessary, tack welding the end of the thin-wall extension in place.
NASA Astrophysics Data System (ADS)
Renfer, Adrian; Tiwari, Manish K.; Brunschwiler, Thomas; Michel, Bruno; Poulikakos, Dimos
2011-09-01
Hydrodynamics in microcavities with cylindrical micropin fin arrays simulating a single layer of a water-cooled electronic chip stack is investigated experimentally. Both inline and staggered pin arrangements are investigated using pressure drop and microparticle image velocimetry (μPIV) measurements. The pressure drop across the cavity shows a flow transition at pin diameter-based Reynolds numbers ( Re d ) ~200. Instantaneous μPIV, performed using a pH-controlled high seeding density of tracer microspheres, helps visualize vortex structure unreported till date in microscale geometries. The post-transition flow field shows vortex shedding and flow impingement onto the pins explaining the pressure drop increase. The flow fluctuations start at the chip outlet and shift upstream with increasing Re d . No fluctuations are observed for a cavity with pin height-to-diameter ratio h/ d = 1 up to Re d ~330; however, its pressure drop was higher than for a cavity with h/d = 2 due to pronounced influence of cavity walls.
Kier, Brandon L.; Anderson, Jordan M.; Andersen, Niels H.
2014-01-01
A hyperstable Pin1 WW domain has been circularly permuted via excision of the fold-nucleating turn; it still folds to form the native three-strand sheet and hydrophobic core features. Multiprobe folding dynamics studies of the normal and circularly permuted sequences, as well as their constituent hairpin fragments and comparable-length β-strand-loop-β-strand models, indicate 2-state folding for all topologies. N-terminal hairpin formation is the fold nucleating event for the wild-type sequence; the slower folding circular permutant has a more distributed folding transition state. PMID:24350581
Effect of Tube Diameter on The Design of Heat Exchanger in Solar Drying system
NASA Astrophysics Data System (ADS)
Husham Abdulmalek, Shaymaa; Khalaji Assadi, Morteza; Al-Kayiem, Hussain H.; Gitan, Ali Ahmed
2018-03-01
The drying of agriculture product consumes a huge fossil fuel rates that demand to find an alternative source of sustainable environmental friendly energy such as solar energy. This work presents the difference between using solar heat source and electrical heater in terms of design aspect. A circular-finned tube bank heat exchanger is considered against an electrical heater used as a heat generator to regenerate silica gel in solar assisted desiccant drying system. The impact of tube diameter on the heat transfer area was investigated for both the heat exchanger and the electrical heater. The fin performance was investigated by determining fin effectiveness and fin efficiency. A mathematical model was developed using MATLAB to describe the forced convection heat transfer between hot water supplied by evacuated solar collector with 70 °C and ambient air flow over heat exchanger finned tubes. The results revealed that the increasing of tube diameter augments the heat transfer area of both heat exchanger and electrical heater. The highest of fin efficiency was around 0.745 and the lowest was around 0.687 while the fin effectiveness was found to be around 0.998.
Effect of a rotor wake on heat transfer from a circular cylinder
NASA Technical Reports Server (NTRS)
Simoneau, R. J.; Morehouse, K. A.; Vanfossen, G. J.; Behning, F. P.
1984-01-01
The effect of a rotor wake on heat transfer to a downstream stator was investigated. The rotor was modeled with a spoked wheel of 24 circular pins 1.59 mm in diameter. One of the stator pins was electrically heated in the midspan region and circumferentially averaged heat transfer coefficients were obtained. The experiment was run in an annular flow wind tunnel using air at ambient temperature and pressure. Reynolds numbers based on stator cylinder diameter ranged from .001 to .00001. Rotor blade passing frequencies ranged from zero to 2500 Hz. Stationary grids were used to vary the rotor inlet turbulence from one to four percent. The rotor-stator spacings were one and two stator pin diameters. In addition to the heat transfer coefficients, turbulence spectra and ensemble averaged wake profiles were measured. At the higher Reynolds numbers, which is the primary range of interest for turbulent heat transfer, the rotor wakes increased Nusselt number from 10 to 45 percent depending on conditions. At lower Reynolds numbers the effect was as much as a factor of two.
NASA Technical Reports Server (NTRS)
Dillenius, M. F. E.; Nielsen, J. N.
1979-01-01
Computer programs are presented which are capable of calculating detailed aerodynamic loadings and pressure distributions acting on pitched and rolled supersonic missile configurations which utilize bodies of circular or elliptical cross sections. The applicable range of angle of attack is up to 20 deg, and the Mach number range is 1.3 to about 2.5. Effects of body and fin vortices are included in the methods, as well as arbitrary deflections of canard or fin panels.
NASA Technical Reports Server (NTRS)
Drexel, Rober E; Mcadams, William H
1945-01-01
Report reviews published data and presents some new data on heat transfer to air flowing in round tubes, in rectangular ducts, and around finned cylinders. The available data for heat transfer to air in straight ducts of rectangular and circular cross section have been correlated in plots of Stanton number versus Reynolds number to provide a background for the study of the data for finned cylinders. Equations are recommended for both the streamlined and turbulent regions, and data are presented for the transition region between turbulent and laminar flow. Use of hexagonal ends on round tubes causes the characteristics of laminar flow to extend to high Reynolds numbers. Average coefficients for the entire finned cylinder have been calculated from the average temperature at the base of the fins and an equation which was derived to allow for the effectiveness of the fins. The available results for each finned cylinder are correlated herein in terms of graphs of Stanton number versus Reynolds number. In general, for a given Reynolds number, the Stanton number increases with increases in both spacing and width of the fins, and is apparently independent of cylinder diameter and temperature difference. For a given coefficient of heat transfer improved baffles and rough or wavy surfaces give a substantial reduction in pumping power per unit of heat transfer surface and a somewhat smaller decrease in pressure drop. (author)
Pressure losses and heat transfer in non-circular channels with hydraulically smooth walls
NASA Technical Reports Server (NTRS)
Malak, J.
1982-01-01
The influence of channel geometry on pressure losses and heat transfer in noncircular channels with hydraulically smooth walls was studied. As a basic assumption for the description of this influence, integral geometrical criteria, selected according to experimental experience, were introduced. Using these geometrical criteria, a large set of experimental data for pressure losses and heat transfer in circular and annular channels with longitudinal fins was evaluated. In this way it as empirically proved that the criteria described channel geometry fairly well.
Pinned orbital moments in uncompensated antiferromagnetic Co doped ZnO
NASA Astrophysics Data System (ADS)
Buchner, Martin; Henne, Bastian; Ney, Verena; Lumetzberger, Julia; Wilhelm, Fabrice; Rogalev, Andrei; Hen, Amir; Ney, Andreas
2018-05-01
Low temperature Co K-edge x-ray magnetic circular dichroism spectra at different field cooling conditions were recorded to study the imprinted magnetization in antiferromagnetic (AFM) Co doped ZnO (Co:ZnO) films which manifests itself in a vertical exchange bias effect. Co:ZnO films with 50% and 60% doping concentrations were investigated to provide a high degree of pinned magnetic moments. The measurements reveal a change at the main absorption energy of the spectra, while the signal obtained at the pre-edge stays unaffected by the cooling conditions. Therefore, the pinned uncompensated AFM moments, resulting in an imprinted magnetization, are predominantly of orbital character and are independent of ferromagnetic layers.
Positive correlation between serum IGF-1 and HDL-C in type 2 diabetes mellitus.
Song, Xiaofei; Teng, Jiali; Wang, Aihong; Li, Xiang; Wang, Jing; Liu, Yanjun
2016-08-01
Dyslipidemia and low levels of high density lipoprotein cholesterol (HDL-C) can increase the risk of atherosclerosis development in people with type 2 diabetes mellitus (T2DM). This study aimed to investigate the correlation between serum HDL-C and insulin-like growth factor-1 (IGF-1), which are crucially involved inT2DM. Serum concentrations of IGF-1, total cholesterol, triglyceride, low density lipoprotein cholesterol, and HDL-C were measured in 498 participants with T2DM without any lipid-modifying medicine prior to study. Participants were divided into three groups according to the 25th and 75th percentile of IGF-1 levels: low IGF-1 group (G1), middle IGF-1 group (G2), and high IGF-1 group (G3), respectively. Serum levels of HDL-C were compared among the three groups. G1 presented a higher body mass index and higher fasting plasma insulin (FINS) than G2 (P<0.05), yet a lower HDL-C than G2 (P<0.05). Moreover, HDL-C, postprandial blood glucose, FINS, postprandial plasma insulin (PINS), hip circumference ratio, glycated hemoglobin A1c were significantly lower in G3 than in G2 (P<0.05). After adjusting for age and gender, serum levels of IGF-1 were negatively correlated with age, duration of disease, waist circumference, FINS, PINS, and insulin resistance, but positively correlated with HDL-C. Each increase of 2.71ng/dl in IGF-I concentration was associated with an increase of 1.34mg/dl in HDL level. IGF-1 serum level in people with T2DM is correlated positively with HDL-C. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.
Aircraft-mounted crash-activated transmitter device
NASA Technical Reports Server (NTRS)
Manoli, R.; Ulrich, B. R. (Inventor)
1976-01-01
An aircraft crash location transmitter tuned to transmit on standard emergency frequencies is reported that is shock mounted in a sealed circular case atop the tail of an aircraft by means of a shear pin designed to fail under a G loading associated with a crash situation. The antenna for the transmitter is a metallic spring blade coiled like a spiral spring around the outside of the circular case. A battery within the case for powering the transmitter is kept trickle charged from the electrical system of the aircraft through a break away connector on the case. When a crash occurs, the resultant ejection of the case from the tail due to a failure of the shear pin releases the free end of the antenna which automatically uncoils. The accompanying separation of the connector effects closing of the transmitter key and results in commencement of transmission.
NASA Astrophysics Data System (ADS)
Pal, Sagnik; Saha, Sujoy Kumar
2015-08-01
The experimental friction factor and Nusselt number data for laminar flow of viscous oil through a circular duct having integral axial corrugation roughness and fitted with twisted tapes with oblique teeth have been presented. Predictive friction factor and Nusselt number correlations have also been presented. The thermohydraulic performance has been evaluated. The major findings of this experimental investigation are that the twisted tapes with oblique teeth in combination with integral axial corrugation roughness perform significantly better than the individual enhancement technique acting alone for laminar flow through a circular duct up to a certain value of fin parameter.
Stability of Pin1 as revealed by thermal and spectroscopic studies
NASA Astrophysics Data System (ADS)
Wang, Jing-Zhang; Lin, Tao; Zhu, Guo-Fei; Du, Lin-Fang
2010-06-01
Pin1 is a two-domain enzyme which has peptidyl-prolyl cis/trans isomerase activity. Pin1 recognizes phospho-Ser/Thr-Pro motifs in cell-signaling proteins, and is both a cancer and an Alzheimer's disease target. The thermal stability of Pin1 was studied intensively by SDS-PAGE, enzymatic activity assay, intrinsic fluorescence spectroscopy and circular dichroism spectroscopy. The activity of Pin1 gradually decreased above 40 °C, and the Tm was 57.6 ± 1.0 °C. Fluorescence experiments indicated that heat treatment induced changes in the substructures in Pin1, resulting in that the polarity in the microenvironments of the tryptophan residues increased. It is assumed that the thermal denaturation of Pin1 involved a three-state transition. The intermediate state of Pin1 at about 60 °C was confirmed by fluorescence emission spectra, the synchronous fluorescence spectra and CD measurements. Decreases in α-helix and β-sheet appeared above 40 °C, which was balanced by an enhancement in unordered coil. The Tm values calculated from α-helix transition and β-sheet transition were 54.6 ± 0.6 °C and 70.7 ± 3.3 °C, respectively. Our results illustrated that Pin1 had a relatively high thermal stability and the WW domain had a higher stability than the PPIase domain.
Study on Fins' Effect of Boiling Flow in Millimeter Channel Heat Exchanger
NASA Astrophysics Data System (ADS)
Watanabe, Satoshi
2005-11-01
Recently, a lot of researches about compact heat exchangers with mini-channels have been carried out with the hope of obtaining a high-efficiency heat transfer, due to the higher ratio of surface area than existing heat exchangers. However, there are many uncertain phenomena in fields such as boiling flow in mini-channels. Thus, in order to understand the boiling flow in mini-channels to design high-efficiency heat exchangers, this work focused on the visualization measurement of boiling flow in a millimeter channel. A transparent acrylic channel (heat exchanger form), high-speed camera (2000 fps at 1024 x 1024 pixels), and halogen lamp (backup light) were used as the visualization system. The channel's depth is 2 mm, width is 30 mm, and length is 400 mm. In preparation for commercial use, two types of channels were experimented on: a fins type and a normal slit type (without fins). The fins are circular cylindrical obstacles (diameter is 5 mm) to promote heat transfer, set in a triangular array (distance between each center point is 10 mm). Especially in this work, boiling flow and heat transfer promotion in the millimeter channel heat exchanger with fins was evaluated using a high-speed camera.
Wang, Jing-Zhang; Liu, Ji; Lin, Tao; Han, Yong-Guang; Luo, Yue; Xi, Lei; Du, Lin-Fang
2013-09-01
The enzyme peptidyl-prolyl cis-trans isomerase (Pin1) may play an important role in preventing the development of Alzheimer's disease (AD). The structural and functional stability of Pin1 is extremely important. Previously, we have determined the stability of Pin1 under stressed conditions, such as thermal treatment and acidic-pH. Considering that aluminum (Al(III)) is well known for its potential neurotoxicity in the pathogenesis of AD, we examined whether Al(III) affects the structure and function of Pin1, by means of a PPIase activity assay, intrinsic fluorescence, circular dichroism (CD) spectroscopy, FTIR, and differential scanning calorimetry (DSC). The intrinsic tryptophan fluorescence measurements mainly show that Al(III) may bind to the clusters nearby W11 and W34 in the WW domain of Pin1, quenching the intrinsic fluorescence of the two tryptophan residues, which possibly results in the decreased binding affinity of Pin1 to substrates. The secondary structural analysis as revealed by FTIR and CD measurements indicate that Al(III) induces the increase in β-sheet and the decrease in α-helix in Pin1. Furthermore, the changes of the thermodynamic parameters for Pin1 as monitored by DSC confirm that the thermal stability of Pin1 significantly increases in the presence of Al(III). The Al(III)-induced structural changes of Pin1 result in a sharp decrease of the PPIase activity of Pin1. To some extent, our research is suggestive that Al(III) may inhibit the isomerization activity of Pin1 in vivo, which may contribute to the pathogenesis of AD. Copyright © 2013. Published by Elsevier Inc.
Pan, De-Bei; Gao, Xiang; Feng, Xia; Pan, Jun-Ting; Zhang, Hong
2016-02-24
Spirals or scroll waves pinned to heterogeneities in cardiac tissues may cause lethal arrhythmias. To unpin these life-threatening spiral waves, methods of wave emission from heterogeneities (WEH) induced by low-voltage pulsed DC electric fields (PDCEFs) and circularly polarized electric fields (CPEFs) have been used in two-dimensional (2D) cardiac tissues. Nevertheless, the unpinning of scroll waves in three-dimensional (3D) cardiac systems is much more difficult than that of spiral waves in 2D cardiac systems, and there are few reports on the removal of pinned scroll waves in 3D cardiac tissues by electric fields. In this article, we investigate in detail the removal of pinned scroll waves in a generic model of 3D excitable media using PDCEF, AC electric field (ACEF) and CPEF, respectively. We find that spherical waves can be induced from the heterogeneities by these electric fields in initially quiescent excitable media. However, only CPEF can induce spherical waves with frequencies higher than that of the pinned scroll wave. Such higher-frequency spherical waves induced by CPEF can be used to drive the pinned scroll wave out of the cardiac systems. We hope this remarkable ability of CPEF can provide a better alternative to terminate arrhythmias caused by pinned scroll waves.
NASA Astrophysics Data System (ADS)
Vasilev, V. Ya; Nikiforova, S. A.
2018-03-01
Experimental studies of thermo-aerodynamic characteristics of non-circular ducts with discrete turbulators on walls and interrupted channels have confirmed the rational enhancement of convective heat transfer, in which the growth of heat transfer outstrips or equals the growth of aerodynamic losses. Determining the regularities of rational (energy-saving) enhancement of heat transfer and the proposed method for comparing the characteristics of smooth-channel (without enhancement) heat exchangers with effective analogs provide new results, confirming the high efficiency of vortex enhancement of convective heat transfer in non-circular ducts of plate-finned heat exchange surfaces. This allows creating heat exchangers with much smaller mass and volume for operation in energy-saving modes.
Phantu, Metinee; Sutthiopad, Malee; Luengviriya, Jiraporn; Müller, Stefan C; Luengviriya, Chaiya
2017-04-01
We present an investigation on the breakup of free and pinned spiral waves under an applied electrical current in the Belousov-Zhabotinsky reaction. Spiral fronts propagating towards the negative electrode are decelerated. A breakup of the spiral waves occurs when some segments of the fronts are stopped by a sufficiently strong electrical current. In the absence of obstacles (i.e., free spiral waves), the critical value of the electrical current for the wave breakup increases with the excitability of the medium. For spiral waves pinned to circular obstacles, the critical electrical current increases with the obstacle diameter. Analysis of spiral dynamics shows that the enhancement of the robustness against the breakup of both free and pinned spiral waves is originated by the increment of wave speed when either the excitability is strengthened or the obstacle size is enlarged. The experimental findings are reproduced by numerical simulations using the Oregonator model. In addition, the simulations reveal that the robustness against the forced breakup increases with the activator level in both cases of free and pinned spiral waves.
The Plastic Flow Field in the Vicinity of the Pin-Tool During Friction Stir Welding
NASA Technical Reports Server (NTRS)
Bernstein, E. L.; Nunes, A. C., Jr.
2000-01-01
The plastic flow field in the vicinity of the pin-tool during Friction Stir Welding (FSW) needs to be understood if a theoretical understanding of the process is to be attained. The structure of welds does not exhibit the flow field itself, but consists in a residue of displacements left by the plastic flow field. The residue requires analysis to extract from it the instantaneous flow field around the pin-tool. A simplified merry-go-round model makes sense of some tracer experiments reported in the literature. A quantitative comparison is made of the displacements of copper wire markers with displacements computed from a hypothetical plastic flow field. The hypothetical plastic flow field consists in a circular rotation field about a translating pin tool with angular velocity varying with radius from the pin centerline. A sharply localized rotational field comprising slip on a surface around the tool agreed better with observations than a distributed slip field occupying a substantial volume around the tool. Both the tracer and the wire displacements support the "rotating plug" model, originally invoked or thermal reasons, of the FSW process.
Mehos, Mark S.; Anselmo, Kenneth M.; Moreno, James B.; Andraka, Charles E.; Rawlinson, K. Scott; Corey, John; Bohn, Mark S.
2002-01-01
A hybrid high-temperature solar receiver is provided which comprises a solar heat-pipe-receiver including a front dome having a solar absorber surface for receiving concentrated solar energy, a heat pipe wick, a rear dome, a sidewall joining the front and the rear dome, and a vapor and a return liquid tube connecting to an engine, and a fossil fuel fired combustion system in radial integration with the sidewall for simultaneous operation with the solar heat pipe receiver, the combustion system comprising an air and fuel pre-mixer, an outer cooling jacket for tangentially introducing and cooling the mixture, a recuperator for preheating the mixture, a burner plenum having an inner and an outer wall, a porous cylindrical metal matrix burner firing radially inward facing a sodium vapor sink, the mixture ignited downstream of the matrix forming combustion products, an exhaust plenum, a fossil-fuel heat-input surface having an outer surface covered with a pin-fin array, the combustion products flowing through the array to give up additional heat to the receiver, and an inner surface covered with an extension of the heat-pipe wick, a pin-fin shroud sealed to the burner and exhaust plenums, an end seal, a flue-gas diversion tube and a flue-gas valve for use at off-design conditions to limit the temperature of the pre-heated air and fuel mixture, preventing pre-ignition.
NASA Astrophysics Data System (ADS)
Wantha, Channarong
2018-02-01
This paper reports on the experimental and simulation studies of the influence of stack geometries and different mean pressures on the cold end temperature of the stack in the thermoacoustic refrigeration system. The stack geometry was tested, including spiral stack, circular pore stack and pin array stack. The results of this study show that the mean pressure of the gas in the system has a significant impact on the cold end temperature of the stack. The mean pressure of the gas in the system corresponds to thermal penetration depth, which results in a better cold end temperature of the stack. The results also show that the cold end temperature of the pin array stack decreases more than that of the spiral stack and circular pore stack geometry by approximately 63% and 70%, respectively. In addition, the thermal area and viscous area of the stack are analyzed to explain the results of such temperatures of thermoacoustic stacks.
SU-E-T-17: A Mathematical Model for PinPoint Chamber Correction in Measuring Small Fields
DOE Office of Scientific and Technical Information (OSTI.GOV)
Li, T; Zhang, Y; Li, X
2014-06-01
Purpose: For small field dosimetry, such as measuring the cone output factor for stereotactic radiosurgery, ion chambers often result in underestimation of the dose, due to both the volume averaging effect and the lack of electron equilibrium. The purpose of this work is to develop a mathematical model, specifically for the pinpoint chamber, to calculate the correction factors corresponding to different type of small fields, including single cone-based circular field and non-standard composite fields. Methods: A PTW 0.015cc PinPoint chamber was used in the study. Its response in a certain field was modeled as the total contribution of many smallmore » beamlets, each with different response factor depending on the relative strength, radial distance to the chamber axis, and the beam angle. To get these factors, 12 cone-shaped circular fields (5mm,7.5mm, 10mm, 12.5mm, 15mm, 20mm, 25mm, 30mm, 35mm, 40mm, 50mm, 60mm) were irradiated and measured with the PinPoint chamber. For each field size, hundreds of readings were recorded for every 2mm chamber shift in the horizontal plane. These readings were then compared with the theoretical doses as obtained with Monte Carlo calculation. A penalized-least-square optimization algorithm was developed to find out the beamlet response factors. After the parameter fitting, the established mathematical model was validated with the same MC code for other non-circular fields. Results: The optimization algorithm used for parameter fitting was stable and the resulted response factors were smooth in spatial domain. After correction with the mathematical model, the chamber reading matched with the Monte Carlo calculation for all the tested fields to within 2%. Conclusion: A novel mathematical model has been developed for the PinPoint chamber for dosimetric measurement of small fields. The current model is applicable only when the beam axis is perpendicular to the chamber axis. It can be applied to non-standard composite fields. Further validation with other type of detectors is being conducted.« less
NASA Astrophysics Data System (ADS)
Xi, Lei; Wang, Yu; He, Qing; Zhang, Qingyan; Du, Linfang
2016-12-01
The binding of epigallocatechin-3-gallate (EGCG) to wild type Pin1 in solution was studied by spectroscopic methods and molecular dynamics simulations in this research to explore the binding mode and inhibition mechanism. The binding constants and number of binding sites per Pin1 for EGCG were calculated through the Stern-Volmer equation. The values of binding free energy and thermodynamic parameters were calculated and indicated that hydrogen bonds, electrostatic interaction and Van der Waals interaction played the major role in the binding process. The alterations of Pin1 secondary structure in the presence of EGCG were confirmed by far-UV circular dichroism spectra. The binding model at atomic-level revealed that EGCG was bound to the Glu12, Lys13, Arg14, Met15 and Arg17 in WW domain. Furthermore, EGCG could also interact with Arg69, Asp112, Cys113 and Ser114 in PPIase domain.
Heat Transfer and Cooling in Gas Turbines
1985-09-01
The friction factor results of the present study are in agreement with Ref. 9, but the heat transfer data for oblong pin fins are not. This is...AG ARD Conference P ioecd igs 353, 62nd Meceting, October ! 98,3 DTW- I" c LrU a : ol-.• ,’ • ![ Hazard Studies for Solid Propeliant Rocket Motors...Internal Flows 71 AGARI) Advisory Report 181 (in English and French). Results of WG 14 (June/August 1983) I’rodueibility and Cost Studies of Aviation
Pan, De-Bei; Gao, Xiang; Feng, Xia; Pan, Jun-Ting; Zhang, Hong
2016-01-01
Spirals or scroll waves pinned to heterogeneities in cardiac tissues may cause lethal arrhythmias. To unpin these life-threatening spiral waves, methods of wave emission from heterogeneities (WEH) induced by low-voltage pulsed DC electric fields (PDCEFs) and circularly polarized electric fields (CPEFs) have been used in two-dimensional (2D) cardiac tissues. Nevertheless, the unpinning of scroll waves in three-dimensional (3D) cardiac systems is much more difficult than that of spiral waves in 2D cardiac systems, and there are few reports on the removal of pinned scroll waves in 3D cardiac tissues by electric fields. In this article, we investigate in detail the removal of pinned scroll waves in a generic model of 3D excitable media using PDCEF, AC electric field (ACEF) and CPEF, respectively. We find that spherical waves can be induced from the heterogeneities by these electric fields in initially quiescent excitable media. However, only CPEF can induce spherical waves with frequencies higher than that of the pinned scroll wave. Such higher-frequency spherical waves induced by CPEF can be used to drive the pinned scroll wave out of the cardiac systems. We hope this remarkable ability of CPEF can provide a better alternative to terminate arrhythmias caused by pinned scroll waves. PMID:26905367
Spence, R.; Streeton, R.J.W.
1956-04-17
The fluid contactor apparatus comprises a cylindrical column mounted co- axially and adapted to rotate within a cylindrical vessel, for the purpose of extracting a solute from am aqueous solution by means of an organic solvent. The column is particularly designed to control the vortex pattern so as to reduce the height of the vortices while, at the same time, the width of the annular radius in the radial direction between the vessel and column is less than half the radius of the column. A plurality of thin annular fins are spaced apart along the rotor approximately twice the radial dimension of the column such that two contrarotating substantially circular vortices are contained within each pair of fins as the column is rotated.
Sheng, Fei-Feng; Dai, Xing-Ping; Qu, Jian; Lei, Guang-Hua; Lu, Hong-Bin; Wu, Jing; Xu, Xiao-Jing; Pei, Qi; Dong, Min; Liu, Ying-Zi; Zhou, Hong-Hao; Liu, Zhao-Qian
2011-08-01
1. In the present study, we investigated the associations of nicotinamide phosphoribosyltransferase (NAMPT)-3186 C/T and -948G/T polymorphisms with the risk of Type 2 diabetes mellitus (T2DM) and their impact on the efficacy of repaglinide in Chinese Han T2DM patients. 2. In all, 170 patients with T2DM and 129 healthy controls were genotyped for NAMPT-948G>T and -3186C>T polymorphisms. Thirty-five patients with different NAMPT -3186 C/T genotypes and the same organic anion-transporting polypeptide 1B1 (OATP1B1521) T/C genotype were randomly selected to undergo 8 weeks preprandial repaglinide treatment (1 mg, three times daily). Serum fasting plasma glucose (FPG), post-prandial plasma glucose (PPG), glycated haemoglobin (HbAlc), fasting serum insulin (FINS), post-prandial serum insulin (PINS), triglyceride (TG), total cholesterol (CHO), homeostasis model assessment of insulin resistance (HOMA-IR), low-density lipoprotein-cholesterol (LDL-C) and high-density lipoprotein-cholesterol (HDL-C) were determined before and after repaglinide treatment. 3. After repaglinide treatment for 8 consecutive weeks, there were significantly decreases in PFG, PPG, HbAlc, CHO and LDL-C, and increases in FINS, HDL-C and the HDL-C : LDL-C ratio, in T2DM patients. The elevated PINS value in patients with CT genotypes was significantly lower than that in patients with the CC and TT genotypes (P < 0.05) and there were significant differences in CHO between patients with the CT genotype and the CC or TT genotype (P < 0.05). 4. The data suggest that the NAMPT -3186C>T polymorphism is significantly associated with plasma levels of PINS and CHO in Chinese T2DM patients with repaglinide monotherapy. © 2011 The Authors. Clinical and Experimental Pharmacology and Physiology © 2011 Blackwell Publishing Asia Pty Ltd.
DOE Office of Scientific and Technical Information (OSTI.GOV)
O'Brien, James Edward; Sohal, Manohar Singh; Huff, George Albert
2002-08-01
A combined experimental and numerical investigation is under way to investigate heat transfer enhancement techniques that may be applicable to large-scale air-cooled condensers such as those used in geothermal power applications. The research is focused on whether air-side heat transfer can be improved through the use of finsurface vortex generators (winglets,) while maintaining low heat exchanger pressure drop. A transient heat transfer visualization and measurement technique has been employed in order to obtain detailed distributions of local heat transfer coefficients on model fin surfaces. Pressure drop measurements have also been acquired in a separate multiple-tube row apparatus. In addition, numericalmore » modeling techniques have been developed to allow prediction of local and average heat transfer for these low-Reynolds-number flows with and without winglets. Representative experimental and numerical results presented in this paper reveal quantitative details of local fin-surface heat transfer in the vicinity of a circular tube with a single delta winglet pair downstream of the cylinder. The winglets were triangular (delta) with a 1:2 height/length aspect ratio and a height equal to 90% of the channel height. Overall mean fin-surface Nusselt-number results indicate a significant level of heat transfer enhancement (average enhancement ratio 35%) associated with the deployment of the winglets with oval tubes. Pressure drop measurements have also been obtained for a variety of tube and winglet configurations using a single-channel flow apparatus that includes four tube rows in a staggered array. Comparisons of heat transfer and pressure drop results for the elliptical tube versus a circular tube with and without winglets are provided. Heat transfer and pressure-drop results have been obtained for flow Reynolds numbers based on channel height and mean flow velocity ranging from 700 to 6500.« less
The Influence of the Size Styles for the Touching Probe for the Roundness of the Deviation
NASA Astrophysics Data System (ADS)
Mizera, Ondrej; Cepova, Lenka
2017-12-01
The article deals with the influence of the sensing touch on the deviation of circularity on the WENZEL LH 65 X3M on 3D machining and using the Metrosoft QUARTIZ R6 software at the VŠB-TU Ostrava Laboratory, Faculty of Mechanical Engineering, Department of Machining, Assembly and engineering metrology. The aim was to analyze the influence of individual sensors on the different lengths of the pin and the diameter of the sensing metod on the accuracy of the measurement of the variance of the circularity.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Manohar S. Sohal
2005-09-01
This report summarizes work at the Idaho National Laboratory to develop strategies to enhance air-side heat transfer in geothermal air-cooled condensers such that it should not significantly increase pressure drop and parasitic fan pumping power. The work was sponsored by the U.S. Department of Energy, NEDO (New Energy and Industrial Technology Development Organization) of Japan, Yokohama National University, and the Indian Institute of Technology, Kanpur, India. A combined experimental and numerical investigation was performed to investigate heat transfer enhancement techniques that may be applicable to largescale air-cooled condensers such as those used in geothermal power applications. A transient heat transfermore » visualization and measurement technique was employed in order to obtain detailed distributions of local heat transfer coefficients on model fin surfaces. Pressure drop measurements were obtained for a variety of tube and winglet configurations using a single-channel flow apparatus that included four tube rows in a staggered array. Heat transfer and pressure drop measurements were also acquired in a separate multiple-tube row apparatus in the Single Blow Test Facility. In addition, a numerical modeling technique was developed to predict local and average heat transfer for these low-Reynolds number flows, with and without winglets. Representative experimental and numerical results were obtained that reveal quantitative details of local finsurface heat transfer in the vicinity of a circular tube with a single delta winglet pair downstream of the cylinder. Heat transfer and pressure-drop results were obtained for flow Reynolds numbers based on channel height and mean flow velocity ranging from 700 to 6500. The winglets were of triangular (delta) shape with a 1:2 or 1:3 height/length aspect ratio and a height equal to 90% of the channel height. Overall mean fin-surface heat transfer results indicate a significant level of heat transfer enhancement (in terms of Colburn j-factor) associated with deployment of the winglets with circular as well as oval tubes. In general, toe-in (common flow up) type winglets appear to have better performance than the toe-out (common flow down) type winglets. Comparisons of heat transfer and pressure drop results for the elliptical tube versus a circular tube with and without winglets are provided. During the course of their independent research, all of the researchers have established that about 10 to 30% enhancement in Colburn j-factor is expected. However, actual increase in heat transfer rate from a heat exchanger employing finned tubes with winglets may be smaller, perhaps on the order of 2 to 5%. It is also concluded that for any specific application, more full-size experimentation is needed to optimize the winglet design for a specific heat exchanger application. If in place of a circular tube, an oval tube can be economically used in a bundle, it is expected that the pressure drop across the tube bundle with the application of vortex generators (winglets) will be similar to that in a conventional circular tube bundle. It is hoped that the results of this research will demonstrate the benefits of applying vortex generators (winglets) on the fins to improve the heat transfer from the air-side of the tube bundle.« less
Stress-intensity factors for cracks emanating from the loaded fastener hole
NASA Technical Reports Server (NTRS)
Shivakumar, V.; Hsu, Y. C.
1977-01-01
Using a series approach and the Muskhelishvili formulation in the two-dimensional theory of elasticity, stress-intensity factors K are derived for problems in which cracks emanate radially from the boundary of an arbitrarily loaded internal circular hole in an infinite plate. Numerical values are obtained for K(I) and K(II) for radial cracks from a hole containing a loose-fitted pin or rivet that is pulled perpendicular to the crack direction in the plane of the plate. The method is a general one for determining K for a set of symmetrically emanating radial cracks for a variety of concentrated or distributed tractions on the circular hole.
TAD- THEORETICAL AERODYNAMICS PROGRAM
NASA Technical Reports Server (NTRS)
Barrowman, J.
1994-01-01
This theoretical aerodynamics program, TAD, was developed to predict the aerodynamic characteristics of vehicles with sounding rocket configurations. These slender, axisymmetric finned vehicle configurations have a wide range of aeronautical applications from rockets to high speed armament. Over a given range of Mach numbers, TAD will compute the normal force coefficient derivative, the center-of-pressure, the roll forcing moment coefficient derivative, the roll damping moment coefficient derivative, and the pitch damping moment coefficient derivative of a sounding rocket configured vehicle. The vehicle may consist of a sharp pointed nose of cone or tangent ogive shape, up to nine other body divisions of conical shoulder, conical boattail, or circular cylinder shape, and fins of trapezoid planform shape with constant cross section and either three or four fins per fin set. The characteristics computed by TAD have been shown to be accurate to within ten percent of experimental data in the supersonic region. The TAD program calculates the characteristics of separate portions of the vehicle, calculates the interference between separate portions of the vehicle, and then combines the results to form a total vehicle solution. Also, TAD can be used to calculate the characteristics of the body or fins separately as an aid in the design process. Input to the TAD program consists of simple descriptions of the body and fin geometries and the Mach range of interest. Output includes the aerodynamic characteristics of the total vehicle, or user-selected portions, at specified points over the mach range. The TAD program is written in FORTRAN IV for batch execution and has been implemented on an IBM 360 computer with a central memory requirement of approximately 123K of 8 bit bytes. The TAD program was originally developed in 1967 and last updated in 1972.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Ranjan, Devesh
Diffusion bonded heat exchangers are the leading candidates for the sCO 2 Brayton cycles in next generation nuclear power plants. Commercially available diffusion bonded heat exchangers utilize set of continuous semi-circular zigzag micro channels to increase the heat transfer area and enhance heat transfer through increased turbulence production. Such heat exchangers can lead to excessive pressure drop as well as flow maldistribution in the case of poorly designed flow distribution headers. The goal of the current project is to fabricate and test potential discontinuous fin patterns for diffusion bonded heat exchangers; which can achieve desired thermal performance at lower pressuremore » drops. Prototypic discontinuous offset rectangular and Airfoil fin surface geometries were chemically etched on to 316 stainless steel plate and sealed against an un-etched flat pate using O-ring seal emulating diffusion bonded heat exchangers. Thermal-hydraulic performance of these prototypic discontinuous fin geometries was experimentally evaluated and compared to the existing data for the continuous zigzag channels. The data generated from this project will serve as the database for future testing and validation of numerical models.« less
Missile Aerodynamics (Aerodynamique des Missiles)
1998-11-01
Magnus effect. effects on a spinning finned cylindrical body. Despite the large As noted above, the source, magnitude and even the direction amount of...axis, and to circular- cylindrical bodies in combination with determine directly the pressures acting on the body. triangular, rectangular, or...pressure drop in smooth cylindrical codes, as well as for testing and checking CFD-based tubes", NACA ARR L4C16, 1944. results. 6. Nielsen, J. N. and
In this paper we report on theoretical and experimental work on aerosol formation in a free turbulent jet. A hot DEHS vapor issues through a circular nozzle into slowly moving cold air. Vapor concentration and temperatures are such that particles are formed via homogeneous nuc...
Antiferromagnetic exchange bias of a ferromagnetic semiconductor by a ferromagnetic metal
DOE Office of Scientific and Technical Information (OSTI.GOV)
Olejnik, K.; Wadley, P.; Haigh, J.
2009-11-05
We demonstrate an exchange bias in (Ga,Mn)As induced by antiferromagnetic coupling to a thin overlayer of Fe. Bias fields of up to 240 Oe are observed. Using element-specific x-ray magnetic circular dichroism measurements, we distinguish an interface layer that is strongly pinned antiferromagnetically to the Fe. The interface layer remains polarized at room temperature.
NASA Astrophysics Data System (ADS)
Cola, Fabrizio; Romagnoli, Alessandro; Hey, Jonathan
2018-05-01
Absorber downsizing for the development of compact absorption chillers is a known challenge of this type of refrigerator. Past studies have revealed how a droplet flow regime can increase the interface area and enhance absorption rates, especially during the droplet formation. This study proposes a space-efficient design for an adiabatic absorber based on a bank of solid pins coupled with a droplet flow regime. Manufacturing through 3D printing technique is used to study the effect of different fin shapes during droplet formation. Droplet behavior is firstly studied analytically through a variational approach. Experiments on pure water are then carried out to validate the model and produce design guidelines for a H2O-LiBr absorber. Results show that the analytical model is more accurate in the regions close to the droplet bottom. The rhomboidal geometry with 120° returned the smallest droplet volume without allowing coalescence of more droplets, ensuring the maintenance of droplet flow and a high surface area for mass transfer. Disturbances in the droplet profiles were observed, caused by the pin-droplet interaction. A map has been then created to allow a quick sizing of the absorber and find its main geometrical and operational features.
Review and status of heat-transfer technology for internal passages of air-cooled turbine blades
NASA Technical Reports Server (NTRS)
Yeh, F. C.; Stepka, F. S.
1984-01-01
Selected literature on heat-transfer and pressure losses for airflow through passages for several cooling methods generally applicable to gas turbine blades is reviewed. Some useful correlating equations are highlighted. The status of turbine-blade internal air-cooling technology for both nonrotating and rotating blades is discussed and the areas where further research is needed are indicated. The cooling methods considered include convection cooling in passages, impingement cooling at the leading edge and at the midchord, and convection cooling in passages, augmented by pin fins and the use of roughened internal walls.
Flow boiling with enhancement devices for cold plate coolant channel design
NASA Technical Reports Server (NTRS)
Boyd, Ronald D.; Turknett, Jerry C.; Smith, Alvin
1989-01-01
The effects of enhancement devices on flow boiling heat transfer in circular coolant channels, which are heated over a fraction of their perimeters, are studied. The variations were examined in both the mean and local (axial, and circumferential) heat transfer coefficients for a circular coolant channel with either smooth walls or with both a twisted tape and spiral finned walls. Improvements were initiated in the present data reduction analysis. These efforts should lead to the development of heat transfer correlations which include effects of single side heat flux and enhancement device configuration. It is hoped that a stage will be set for the study of heat transfer and pressure drop in single sided heated systems under zero gravity conditions.
Stoppers in RED II distraction device: is it possible to prevent pin migration?
Mavili, Mehmet Emin; Vargel, Ibrahim; Tunçbilek, Gökhan
2004-05-01
Distraction osteogenesis has become popular for the treatment of hypoplastic congenital craniomaxillofacial anomalies. Rigid external distraction (RED II) after Le Fort III osteotomy was shown to be a highly effective treatment for the management of midface hypoplasia. This device is used with a halo vest, which is placed at the cranial equator. Intracranial penetration of the fixation pins of the halo is one of the complications of an external distraction device. To prevent pin penetration in rigid external distraction, the authors designed polylactic acid/polyglycolic acid (PLA/PGA) plates that were circular; the plates were 0.8 cm in diameter and had 1.5-mm holes in the center, through which the tip of the pins would pass. To quantify the applied torque by manual tightening of the screws of the distraction device and to measure intraosseous cone depth created by the penetration of the conical part of the screws with and without the PLA/PGA composite stopper, first an in vitro experiment was undertaken on cadaver. Then these PLA/PGA plaques, or stoppers, were placed over the bone surfaces of the cranium of the patients where the tip of the pins press. PLA/PGA stoppers are malleable and adapt their shape to the interactive forces between bone and the pins. They act as a second barrier, and spread the pressure of the screws to larger surfaces, thus securing better stabilization. The penetration of wider portions of the screw into scalp is reduced, minimizing the scalp damage caused by the screws. Biodegradable and biocompatible PLA/PGA stoppers avoid intracranial migration of the fixation pins, especially in children.
USDA-ARS?s Scientific Manuscript database
Atlantic salmon fry were stocked into twelve circular 0.5 m3 tanks in a flow-through system and exposed to either high (1.5-2 body-lengths per second, or BL/s) or low (less than 0.5 BL/s) swimming speeding and high (100% saturation) or low (70% saturation) dissolved oxygen (DO) while being raised fr...
Bending Tests of Circular Cylinders of Corrugated Aluminum-alloy Sheet
NASA Technical Reports Server (NTRS)
Buckwalter, John C; Reed, Warren D; Niles, Alfred S
1937-01-01
Bending tests were made of two circular cylinders of corrugated aluminum-alloy sheet. In each test failure occurred by bending of the corrugations in a plane normal to the skin. It was found, after analysis of the effect of short end bays, that the computed stress on the extreme fiber of a corrugated cylinder is in excess of that for a flat panel of the same basic pattern and panel length tested as a pin-ended column. It is concluded that this increased strength was due to the effects of curvature of the pitch line. It is also concluded from the tests that light bulkheads closely spaced strengthen corrugated cylinders very materially.
NASA Astrophysics Data System (ADS)
Gokce, Zeki Ozgur
The gas turbine is one of the most important parts of the air-breathing jet engine. Hence, improving its efficiency and rendering it operable under high temperatures are constant goals for the aerospace industry. Two types of flow within the gas turbine are of critical relevance: The flow around the first row of stator blades (also known as the nozzle guide vane blade - NGV) and the cooling flow inside the turbine blade cooling channel. The subject of this thesis work was to search for methods that could improve the characteristics of these two types of flows, thus enabling superior engine performance. The innovative aspect of our work was to apply an endwall shape modification previously employed by non-aerospace industries for cooling applications, to the gas turbine cooling flow which is vital to aerospace propulsion. Since the costs of investigating the possible benefits of any idea via extensive experiments could be quite high, we decided to use computational fluid dynamics (CFD) followed by experimentation as our methodology. We decided to analyze the potential benefits of using vortex generators (VGs) as well as the rectangular endwall fence. Since the pin-fins used in cooling flow are circular cylinders, and since the boundary layer flow is mainly characterized by the leading edge diameter of the NGV blade, we modeled both the pin-fins and the NGV blade as vertical circular cylinders. The baseline case consisted of the cylinder(s) being subjected to cross flow and a certain amount of freestream turbulence. The modifications we made on the endwall consisted of rectangular fences. In the case of the cooling flow, we used triangular shaped, common flow up oriented, delta winglet type vortex generators as well as rectangular endwall fences. The channel contained singular cylinders as well as staggered rows of multiple cylinders. For the NGV flow, a rectangular endwall fence and a singular cylinder were utilized. Using extensive CFD modeling and analysis, we confirmed that placing a rectangular endwall fence upstream of the cylinder created additional turbulent mixing in the domain. This led to increased mixing of the cooler flow in the freestream and the hotter flow near the endwall. As a result, we showed that adding a rectangular fence created a 10% mean heat transfer increase downstream of the cylinder. When vortex generators are used, as the flow passes over the sharp edges of the vortex generators, it separates and continues downstream in a rolling, helical pattern. Combined with the effect generated by the orientation of the vortex generators, this flow structure mixes the higher momentum fluid in the freestream with lower momentum fluid in the boundary layer. Similar turbulent mixing behavior is observed over the entire domain, near the cylinders and the side walls. As a result, the heat transfer levels over the wall surfaces are increased and improved cooling is achieved. The improvements in heat transfer are obtained at the expense of acceptable pressure losses across the cooling channel. When the vortex generators are used, the CFD modeling studies showed that overall heat transfer improvements as high as 27% compared to the baseline case are observed inside a domain containing multiple rows of cylinders. A price in the form of 13% pressure loss increase across the channel is paid for the heat transfer benefits. Experiments conducted in the open loop wind tunnel of the Turbomachinery Aero-Heat Transfer Laboratory of the Department of Aerospace Engineering of Penn State University supported the general positive trend of these findings, with a 14% overall increase in heat transfer over the constant heat flux surface when vortex generators are installed, accompanied by an 8% increase in pressure loss. (Abstract shortened by UMI.)
Huang, Qiong; Yin, Ji-Ye; Dai, Xing-Ping; Wu, Jing; Chen, Xiang; Deng, Cai-Shu; Yu, Min; Gong, Zhi-Cheng; Zhou, Hong-Hao; Liu, Zhao-Qian
2010-12-01
Genome-wide association studies (GWASs) identified that SLC30A8 genetic polymorphism was a risk of type 2 diabetes mellitus (T2DM) in several populations. This study aimed to investigate whether the SLC30A8 rs13266634 and rs16889462 polymorphisms were associated with T2DM susceptibility and repaglinide therapeutic efficacy in Chinese T2DM patients. We conducted a case-control study of 443 T2DM patients and 229 healthy volunteers to identify SLC30A8 rs13266634 and rs16889462 genotypes by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) assay. Forty-eight patients were randomly selected and underwent an 8-week repaglinide treatment (3 mg/d). Fasting plasma glucose (FPG), postprandial plasma glucose (PPG), glycated hemoglobin (HbAlc), fasting serum insulin (FINS), postprandial serum insulin (PINS), homeostasis model assessment for insulin resistance (HOMA-IR), serum triglyceride, total cholesterol (TC), low-density lipoprotein-cholesterol (LDL-c) and high-density lipoprotein-cholesterol (HDL-c) were determined before and after repaglinide treatment. SLC30A8 rs13266634 risk C allele frequency was higher in T2DM patients than in healthy controls (P < 0.05). There was a better repaglinide response on FINS (P < 0.05) and PINS (P < 0.01) in patients with rs13266634 CT+TT genotypes compared with CC genotype carriers. Patients with rs16889462 GA genotype showed an enhanced repaglinide efficacy on FPG (P < 0.01), PPG (P < 0.01) and HbAlc (P < 0.05) compared with GG genotype individuals. SLC30A8 rs13266634 and rs16889462 polymorphisms were associated with repaglinide therapeutic efficacy in Chinese T2DM patients.
Mechanics of advancing pin-loaded contacts with friction
NASA Astrophysics Data System (ADS)
Sundaram, Narayan; Farris, T. N.
2010-11-01
This paper considers finite friction contact problems involving an elastic pin and an infinite elastic plate with a circular hole. Using a suitable class of Green's functions, the singular integral equations governing a very general class of conforming contact problems are formulated. In particular, remote plate stresses, pin loads, moments and distributed loading of the pin by conservative body forces are considered. Numerical solutions are presented for different partial slip load cases. In monotonic loading, the dependence of the tractions on the coefficient of friction is strongest when the contact is highly conforming. For less conforming contacts, the tractions are insensitive to an increase in the value of the friction coefficient above a certain threshold. The contact size and peak pressure in monotonic loading are only weakly dependent on the pin load distribution, with center loads leading to slightly higher peak pressure and lower peak shear than distributed loads. In contrast to half-plane cylinder fretting contacts, fretting behavior is quite different depending on whether or not the pin is allowed to rotate freely. If pin rotation is disallowed, the fretting tractions resemble half-plane fretting tractions in the weakly conforming regime but the contact resists sliding in the strongly conforming regime. If pin rotation is allowed, the shear traction behavior resembles planar rolling contacts in that one slip zone is dominant and the peak shear occurs at its edge. In this case, the effects of material dissimilarity in the strongly conforming regime are only secondary and the contact never goes into sliding. Fretting tractions in the forward and reversed load states show shape asymmetry, which persists with continued load cycling. Finally, the governing integro-differential equation for full sliding is derived; in the limiting case of no friction, the same equation governs contacts with center loading and uniform body force loading, resulting in identical pressures when their resultants are equal.
The Flow Field Downstream of a Dynamic Low Aspect Ratio Circular Cylinder: A Parametric Study
NASA Astrophysics Data System (ADS)
Gildersleeve, Samantha; Dan, Clingman; Amitay, Michael
2015-11-01
Flow past a static, low aspect ratio cylinder (pin) has shown the formation of vortical structures, namely the horseshoe and arch-type vortex. These vortical structures may have substantial effects in controlling flow separation over airfoils. In the present experiments, the flow field associated with a low aspect ratio cylinder as it interacts with a laminar boundary layer under static and dynamic conditions was investigated through a parametric study over a flat plate. As a result of the pin being actuated in the wall-normal direction, the structures formed in the wake of the pin were seen to be a strong function of actuation amplitude, driving frequency, and aspect ratio of the cylinder. The study was conducted at a Reynolds number of 1875, based on the local boundary layer thickness, with a free stream velocity of 10 m/s. SPIV data were collected for two aspect ratios of 0.75 and 1.125, actuation amplitudes of 6.7% and 16.7%, and driving frequencies of 175 Hz and 350 Hz. Results indicate that the presence and interactions between vortical structures are altered in comparison to the static case and suggest increased large-scale mixing when the pin is driven at the shedding frequency (350 Hz). Supported by the Boeing Company.
A hip wear simulator with 100 test stations.
Saikko, V
2005-09-01
A novel high-capacity hip wear simulator of the pin-on-disc type was designed, built, and validated. This so-called Super-CTPOD (circularly translating pin-on-disc) device has as many as 100 separate test stations, being an advanced version of the previously validated 12-station CTPOD. A validity test was done so that in all stations the specimens and the test conditions were as similar as possible. Hence, for the first time in this field, an adequate number of similar tests was done for a proper statistical analysis of wear data. The pins were conventional, gamma-sterilized ultra-high molecular weight polyethylene, and the discs were polished CoCr. The lubricant was diluted calf serum and the test length 3 million cycles. In the course of the test, the pins became highly polished, whereas the discs remained practically unchanged. The majority of the polyethylene wear particles were rounded, with a mean diameter of 0.25 microm. The 100 wear factor values computed from the 100 steady state wear rate values of the pins were normally distributed, the mean +/- 95 per cent confidence interval being 1.63 +/- 0.017 x 10(-6) mm3 /N m. The standard deviation was 5.4 per cent of the mean. There were no outliers. The wear mechanisms and the wear factor agreed well with clinical findings. Altogether, the Super-CTPOD test system was shown to be a unique combination of validity, low variation, capacity, efficiency, reliability, productivity, economy, ease of operation, and compact size.
NASA Technical Reports Server (NTRS)
Quade, D. A.
1978-01-01
The pylon loading at the drop test vehicle and wing interface attack points is presented. The loads shown are determined using a stiffness method, which assumes the side stiffness of the forward hook guide and the fore and aft stiffness of each drag pin to be equal. The net effect of this assumption is that the forward hook guide reacts approximately 96% of the drop test vehicle yawing moment. For a comparison of these loads to previous X-15 analysis design loadings, see Volume 1 of this document.
NASA Astrophysics Data System (ADS)
Wang, YongSheng; Ding, WeiDong; Yan, JiaQi; Wang, YaNan
2017-09-01
Atmospheric pressure glow discharge (APGD) has been widely used in the industrial field. The industrial applications are based on achieving stable and diffusive APGD in a relatively large space. The existing sources only achieved stable and diffusive APGD between a short inter-electrode distance within 5 millimeters. In this paper, the effect of a transverse stationary magnetic field on the diffusion of filamentary APGD was studied in a pin-to-ring coaxial gap. The APGD was driven by a high-voltage resonant power supply, and the stationary magnetic field was supplied by a permanent magnet. The stable and diffusive APGD was achieved in the circular area, which diameter was 20 millimeters. The experimental results revealed that more collision ionization occurred and the plasma was distributed diffusively in the discharge gap by applying the external transverse magnetic field. Besides, it is likely to obtain more stable and diffusive APGD in the coaxial pin-to-ring discharge gap when adjusting the input voltage, transverse magnetic flux density and resonant frequency of the power supply.
NASA Astrophysics Data System (ADS)
Amini, Amirhossein; Homsy, G. M.
2017-04-01
We study the evolution of the profile of a two-dimensional volatile liquid droplet that is evaporating on a flat heated substrate. We adopt a one-sided model with thermal control that, together with the lubrication approximation, results in an evolution equation for the local height of the droplet. Without requiring any presumption for the shape of the drop, the problem is formulated for the two modes of evaporation: a pinned contact line and a moving contact line with fixed contact angle. Numerical solutions are provided for each case. For the pinned contact line case, we observe that after a time interval the contact angle dynamics become nonlinear and, interestingly, the local contact angle goes to zero in advance of total evaporation of the drop. For the case of a moving contact line, in which the singularity at the contact line is treated by a numerical slip model, we find that the droplet nearly keeps its initial circular shape and that the contact line recedes with constant speed.
Contact Geometry and Distribution of Plasma Generated in the Vicinity of Sliding Contact
NASA Astrophysics Data System (ADS)
Nakayama, Keiji
2007-09-01
The effect of the geometry of the smaller sliding partner on plasma (triboplasma) generation has been investigated as a function of the tip radius of a diamond pin, which slides against a single crystal sapphire disk under atmospheric dry air pressure. It was found that the diameter and the total intensity of the circular triboplasma increase parabolically with an increase in the tip radius of the pin under constant normal force and sliding velocity. The plasma is most intense at the crossing point of the plasma ring and the frictional track in the plasma circle. The gap distance at the crossing point is independent of the tip radius. The ring diameter increases with an increase in the tip radius, keeping the gap distance constant and obeying Paschen’s law of gas discharge.
Effects of Be acceptors on the spin polarization of carriers in p-i-n resonant tunneling diodes
DOE Office of Scientific and Technical Information (OSTI.GOV)
Awan, I. T.; Galvão Gobato, Y.; Galeti, H. V. A.
In this paper, we have investigated the effect of Be acceptors on the electroluminescence and the spin polarization in GaAs/AlAs p-i-n resonant tunneling diodes. The quantum well emission comprise two main lines separated by ∼20 meV attributed to excitonic and Be-related transitions, which intensities show remarkably abrupt variations at critical voltages, particularly at the electron resonant peak where it shows a high-frequency bistability. The circular-polarization degree of the quantum-well electroluminescence also shows strong and abrupt variations at the critical bias voltages and it attains relatively large values (of ∼−75% at 15 T). These effects may be explored to design novel devices formore » spintronic applications such as a high-frequency spin-oscillators.« less
Knee arthrodesis with circular external fixation.
Garberina, M J; Fitch, R D; Hoffmann, E D; Hardaker, W T; Vail, T P; Scully, S P
2001-01-01
Knee arthrodesis can enable limb salvage in patients with disability secondary to trauma, infected total knee arthroplasty, pyarthrosis, and other complications. Historically, intramedullary nailing has resulted in the highest overall knee fusion rates. However, intramedullary nailing is relatively contraindicated in the presence of active infection. Nineteen patients who underwent knee arthrodesis with circular external fixation were studied retrospectively. Postoperative radiographs were evaluated for evidence of bony fusion, which was defined as trabecular bridging between the femur and tibia. Patients were interviewed and graded using the functional assessment portion of the Knee Society clinical rating system. Fusion was successful in 13 of 19 (68%) patients. Overall, patients spent an average of 4 months 8 days wearing the circular external fixator. Average time to radiographic and clinical evidence of arthrodesis (defined as lack of motion across the fusion site) was 4 months 18 days. No patient with successful fusion considered himself or herself housebound. All but one of these patients require some form of assistive device for ambulation. Complications occurred in 16 of 19 (84%) patients overall. Superficial pin tract infection (55%) and nonunion (32%) were the most common. Circular external fixation is an effective method for obtaining knee arthrodesis in patients who are not good candidates for intramedullary nailing.
NASA Technical Reports Server (NTRS)
Quade, D. A.
1978-01-01
The pylon loading at the drop test vehicle and wing interface attach points is presented. The loads shown are determined using a stiffness method, which assumes the side stiffness of the foreward hook guide to be one-fourth of the fore and aft stiffness of each drag pin. The net effect of this assumption is that the forward hook guide reacts approximately 85% of the drop test vehicle yawing moment. For a comparison of these loads to previous X-15 analysis design loadings, see Volume 1 of this document.
Analytical approximations for spiral waves
DOE Office of Scientific and Technical Information (OSTI.GOV)
Löber, Jakob, E-mail: jakob@physik.tu-berlin.de; Engel, Harald
2013-12-15
We propose a non-perturbative attempt to solve the kinematic equations for spiral waves in excitable media. From the eikonal equation for the wave front we derive an implicit analytical relation between rotation frequency Ω and core radius R{sub 0}. For free, rigidly rotating spiral waves our analytical prediction is in good agreement with numerical solutions of the linear eikonal equation not only for very large but also for intermediate and small values of the core radius. An equivalent Ω(R{sub +}) dependence improves the result by Keener and Tyson for spiral waves pinned to a circular defect of radius R{sub +}more » with Neumann boundaries at the periphery. Simultaneously, analytical approximations for the shape of free and pinned spirals are given. We discuss the reasons why the ansatz fails to correctly describe the dependence of the rotation frequency on the excitability of the medium.« less
Modeling of AA5083 Material-Microstructure Evolution During Butt Friction-Stir Welding
2010-07-01
a rigid material. Its density and thermal properties are set to that of AISI- H13 , the hot-worked tool steel which is often used as a FSW- tool ...joining process (Ref 1-3). Within FSW, a (typically) cylindrical tool - pin (threaded at the bottom and terminated with a circular-plate shape shoulder...applied to the shoulder and owing to frictional sliding and plastic deforma- tion, substantial amount of heat is generated at the tool /work- piece
Debuisson, Damien; Merlen, Alain; Senez, Vincent; Arscott, Steve
2016-03-22
We present an experimental study of stick-jump (SJ) evaporation of strongly pinned nanoliter volume sessile water droplets drying on micropatterned surfaces. The evaporation is studied on surfaces composed of photolithographically micropatterned negative photoresist (SU-8). The micropatterning of the SU-8 enables circular, smooth, trough-like features to be formed which causes a very strong pinning of the three phase (liquid-vapor-solid) contact line of an evaporating droplet. This is ideal for studying SJ evaporation as it contains sequential constant contact radius (CCR) evaporation phases during droplet evaporation. The evaporation was studied in nonconfined conditions, and forced convection was not used. Micropatterned concentric circles were defined having an initial radius of 1000 μm decreasing by a spacing ranging from 500 to 50 μm. The droplet evaporates, successively pinning and depinning from circle to circle. For each pinning radius, the droplet contact angle and volume are observed to decrease quasi-linearly with time. The experimental average evaporation rates were found to decrease with decreasing pining radii. In contrast, the experimental average evaporation flux is found to increase with decreasing droplet radii. The data also demonstrate the influence of the initial contact angle on evaporation rate and flux. The data indicate that the total evaporation time of a droplet depends on the specific micropattern spacing and that the total evaporation time on micropatterned surfaces is always less than on flat, homogeneous surfaces. Although the surface patterning is observed to have little effect on the average droplet flux-indicating that the underlying evaporation physics is not significantly changed by the patterning-the total evaporation time is considerably modified by patterning, up to a factor or almost 2 compared to evaporation on a flat, homogeneous surface. The closely spaced concentric circle pinning maintains a large droplet radius and small contact angle from jump to jump; the result is a large evaporation rate leading to faster evaporation.
NASA Astrophysics Data System (ADS)
Greiner, Nathan
Core simulations for Pressurized Water Reactors (PWR) is insured by a set of computer codes which allows, under certain assumptions, to approximate the physical quantities of interest, such as the effective multiplication factor or the power or temperature distributions. The neutronics calculation scheme relies on three great steps : -- the production of an isotopic cross-sections library ; -- the production of a reactor database through the lattice calculation ; -- the full-core calculation. In the lattice calculation, in which Boltzmann's transport equation is solved over an assembly geometry, the temperature distribution is uniform and constant during irradiation. This represents a set of approximations since, on the one hand, the temperature distribution in the assembly is not uniform (strong temperature gradients in the fuel pins, discrepancies between the fuel pins) and on the other hand, irradiation causes the thermal properties of the pins to change, which modifies the temperature distribution. Our work aims at implementing and introducing a neutronics-thermomechanics coupling into the lattice calculation to finely discretize the temperature distribution and to study its effects. To perform the study, CEA (Commissariat a l'Energie Atomique et aux Energies Alternatives) lattice code APOLLO2 was used for neutronics and EDF (Electricite De France) code C3THER was used for the thermal calculations. We show very small effects of the pin-scaled coupling when comparing the use of a temperature profile with the use of an uniform temperature over UOX-type and MOX-type fuels. We next investigate the thermal feedback using an assembly-scaled coupling taking into account the presence of large water gaps on an UOX-type assembly at burnup 0. We show the very small impact on the calculation of the hot spot factor. Finally, the coupling is introduced into the isotopic depletion calculation and we show that reactivity and isotopic number densities deviations remain small albeit not negligible for UOX-type and MOX-type assemblies. The specific behavior of gadolinium-stuffed fuel pins in an UO2Gd2O 3-type assembly is highlighted.
Flow boiling with enhancement devices for cold plate coolant channel design
NASA Technical Reports Server (NTRS)
Boyd, Ronald D., Sr.; Smith, Alvin
1990-01-01
The use of flow boiling for thermal energy transport is intended to provide an alternative for accommodating higher heat fluxes in commercial space systems. The objectives are to: (1) examine the variations in both the mean and local (axial and circumferential) heat transfer coefficients for a circular coolant channel with either smooth walls, spiral fins, or both spiral fins and a twisted tape; (2) examine the effects of channel diameter and subcooling; and (3) develop an improved reduction analysis and/or suggest possible heat transfer correlation of the present data. Freon-11 is the working fluid. Two-dimensional (circumferential and axial) wall temperature distributions were measured for coolant channels with the above noted internal geometries. The flow regimes which are being studied are: (1) single phase; (2) subcooled flow boiling; and (3) stratified flow boiling. The inside diameter of all test sections is near 1.0 cm. Cicumferentially averaged heat transfer coefficients at several axial locations were obtained for selected coolant channels for a mass velocity of 210 kg/sq m s, an exit pressure of 0.19 MPa (absolute), and an inlet subcooling of 20.8 C. Overall (averaged over the entire channel) heat transfer coefficients were compared for the above channel geometries. This comparison showed that the channel with large pitch spiral fins had higher heat transfer coefficients at all power levels.
Waldrop, Thomas; Summerfelt, Steven T.; Mazik, Patricia M.; Good, Christopher
2018-01-01
Swimming exercise, typically measured in body-lengths per second (BL/s), and dissolved oxygen (DO), are important environmental variables in fish culture. While there is an obvious physiological association between these two parameters, their interaction has not been adequately studied in Atlantic salmon Salmo salar. Because exercise and DO are variables that can be easily manipulated in modern aquaculture systems, we sought to assess the impact of these parameters, alone and in combination, on the performance, health and welfare of juvenile Atlantic salmon. In our study, Atlantic salmon fry were stocked into 12 circular 0.5 m3 tanks in a flow-through system and exposed to either high (1.5–2 BL/s) or low (<0.5 BL/s) swimming speeding and high (100% saturation) or low (70% saturation) DO while being raised from 10 g to approximately 350 g in weight. Throughout the study period, we assessed the impacts of exercise and DO concentration on growth, feed conversion, survival and fin condition. By study's end, both increased swimming speed and higher DO were independently associated with a statistically significant increase in growth performance (p < .05); however, no significant differences were noted in survival and feed conversion. Caudal fin damage was associated with low DO, while right pectoral fin damage was associated with higher swimming speed. Finally, precocious male sexual maturation was associated with low swimming speed. These results suggest that providing exercise and dissolved oxygen at saturation during Atlantic salmon early rearing can result in improved growth performance and a lower incidence of precocious parr.
Thompson, J T; Bartol, I K; Baksi, A E; Li, K Y; Krueger, P S
2010-04-01
Understanding the extent to which changes in muscle form and function underlie ontogenetic changes in locomotory behaviors and performance is important in understanding the evolution of musculoskeletal systems and also the ecology of different life stages. We explored ontogenetic changes in the structure, myosin heavy chain (MHC) expression and contractile properties of the circular muscles that provide power for jet locomotion in the long-finned squid Doryteuthis pealeii. The circular muscle fibers of newly hatched paralarvae had different sizes, shapes, thick filament lengths, thin:thick filament ratio, myofilament organization and sarcoplasmic reticulum (SR) distribution than those of adults. Viewed in cross section, most circular muscle cells were roughly triangular or ovoid in shape with a core of mitochondria; however, numerous muscle cells with crescent or other unusual cross-sectional shapes and muscle cells with unequal distributions of mitochondria were present in the paralarvae. The frequency of these muscle cells relative to 'normal' circular muscle cells ranged from 1:6 to 1:10 among the 19 paralarvae we surveyed. The thick filaments of the two types of circular fibers, superficial mitochondria-rich (SMR) and central mitochondria-poor (CMP), differed slightly in length among paralarvae with thick filament lengths of 0.83+/-0.15 microm and 0.71+/-0.1 microm for the SMR and CMP fibers, respectively (P 0.05; ANOVA). During ontogeny the thick filament lengths of both the CMP and SMR fibers increased significantly to 1.78+/-0.27 microm and 3.12+/-0.56 microm, respectively, in adults (P<0.0001 for both comparisons; ANOVA with Tukey's highly significant difference post hoc tests). When sectioned parallel to their long axes, the SMR and CMP fibers of both paralarvae and adults exhibited the myofilament arrangements typical of obliquely striated muscle cells but the angle of obliquity of the dense bodies was 22.8+/-2.4 deg. and 4.6+/-0.87 deg. for paralarvae and adults, respectively. There were also differences in the distribution of the anastomosing network of SR. In paralarvae, the outer and central zones of SR were well developed but the intramyoplasmic zone was greatly reduced in some cells or was scattered non-uniformly across the myoplasm. Whereas in adults the intramyoplasmic SR region was composed primarily of flattened tubules, it was composed primarily of rounded vesicles or tubules when present in the paralarvae. The ontogenetic differences in circular muscle structure were correlated with significant differences in their contractile properties. In brief tetanus at 20 degrees C, the mean unloaded shortening velocity of the paralarval circular muscle preparations was 9.1 L(0) s(-1) (where L(0) was the preparation length that generated the peak isometric stress), nearly twice that measured in other studies for the CMP fibers of adults. The mean peak isometric stress was 119+/-15 mN mm(-2) physiological cross section, nearly half that measured for the CMP fibers of adults. Reverse transcriptase-polymerase chain reaction analysis of paralarval and adult mantle samples revealed very similar expression patterns of the two known isoforms of squid MHC. The ontogenetic differences in the structure and physiology of the circular muscles may result in more rapid mantle movements during locomotion. This prediction is consistent with jet pulse durations observed in other studies, with shorter jet pulses providing hydrodynamic advantages for paralarvae.
A generalized one-dimensional computer code for turbomachinery cooling passage flow calculations
NASA Technical Reports Server (NTRS)
Kumar, Ganesh N.; Roelke, Richard J.; Meitner, Peter L.
1989-01-01
A generalized one-dimensional computer code for analyzing the flow and heat transfer in the turbomachinery cooling passages was developed. This code is capable of handling rotating cooling passages with turbulators, 180 degree turns, pin fins, finned passages, by-pass flows, tip cap impingement flows, and flow branching. The code is an extension of a one-dimensional code developed by P. Meitner. In the subject code, correlations for both heat transfer coefficient and pressure loss computations were developed to model each of the above mentioned type of coolant passages. The code has the capability of independently computing the friction factor and heat transfer coefficient on each side of a rectangular passage. Either the mass flow at the inlet to the channel or the exit plane pressure can be specified. For a specified inlet total temperature, inlet total pressure, and exit static pressure, the code computers the flow rates through the main branch and the subbranches, flow through tip cap for impingement cooling, in addition to computing the coolant pressure, temperature, and heat transfer coefficient distribution in each coolant flow branch. Predictions from the subject code for both nonrotating and rotating passages agree well with experimental data. The code was used to analyze the cooling passage of a research cooled radial rotor.
Mode I analysis of a cracked circular disk subject to a couple and a force
NASA Technical Reports Server (NTRS)
Gross, B.
1978-01-01
Mode I stress intensity coefficients were obtained for an edge-cracked disk (round compact specimen). Results for this plane elastostatic problem, obtained by a boundary collocation analysis are presented for A/D ratios of 0.35 to 1, where A is the crack length and D is the disk diameter. The results presented are for two complementary types of loading. By superposition of these results the stress intensity factor for any practical load line location of a pin-loaded round compact specimen can be obtained.
NASA Technical Reports Server (NTRS)
Farley, Gary L.; Seshadri, Banavara R.
2005-01-01
An analysis based investigation of aluminum with metal matrix composite selectively reinforced single- and multi-hole specimens was performed and their results compared with results from geometrically comparable non-reinforced specimens. All reinforced specimens exhibited a significant increase in performance. Performance increase of up to 170 percent was achieved. Specimen failure modes were consistent with results from reinforced polymeric matrix composite specimens. Localized reinforcement application (circular) proved as effective as a broader area (strip) reinforcement. Also, selective reinforcement is an excellent method of increasing the performance of multi-hole specimens.
Advanced fabrication techniques for hydrogen-cooled engine structures
NASA Technical Reports Server (NTRS)
Buchmann, O. A.; Arefian, V. V.; Warren, H. A.; Vuigner, A. A.; Pohlman, M. J.
1985-01-01
Described is a program for development of coolant passage geometries, material systems, and joining processes that will produce long-life hydrogen-cooled structures for scramjet applications. Tests were performed to establish basic material properties, and samples constructed and evaluated to substantiate fabrication processes and inspection techniques. Results of the study show that the basic goal of increasing the life of hydrogen-cooled structures two orders of magnitude relative to that of the Hypersonic Research Engine can be reached with available means. Estimated life is 19000 cycles for the channels and 16000 cycles for pin-fin coolant passage configurations using Nickel 201. Additional research is required to establish the fatigue characteristics of dissimilar-metal coolant passages (Nickel 201/Inconel 718) and to investigate the embrittling effects of the hydrogen coolant.
Rummer, Jodie L.; Binning, Sandra A.; Roche, Dominique G.; Johansen, Jacob L.
2016-01-01
Respirometry is frequently used to estimate metabolic rates and examine organismal responses to environmental change. Although a range of methodologies exists, it remains unclear whether differences in chamber design and exercise (type and duration) produce comparable results within individuals and whether the most appropriate method differs across taxa. We used a repeated-measures design to compare estimates of maximal and standard metabolic rates (MMR and SMR) in four coral reef fish species using the following three methods: (i) prolonged swimming in a traditional swimming respirometer; (ii) short-duration exhaustive chase with air exposure followed by resting respirometry; and (iii) short-duration exhaustive swimming in a circular chamber. We chose species that are steady/prolonged swimmers, using either a body–caudal fin or a median–paired fin swimming mode during routine swimming. Individual MMR estimates differed significantly depending on the method used. Swimming respirometry consistently provided the best (i.e. highest) estimate of MMR in all four species irrespective of swimming mode. Both short-duration protocols (exhaustive chase and swimming in a circular chamber) produced similar MMR estimates, which were up to 38% lower than those obtained during prolonged swimming. Furthermore, underestimates were not consistent across swimming modes or species, indicating that a general correction factor cannot be used. However, SMR estimates (upon recovery from both of the exhausting swimming methods) were consistent across both short-duration methods. Given the increasing use of metabolic data to assess organismal responses to environmental stressors, we recommend carefully considering respirometry protocols before experimentation. Specifically, results should not readily be compared across methods; discrepancies could result in misinterpretation of MMR and aerobic scope. PMID:27382471
Rotatable electric cable connecting system
NASA Technical Reports Server (NTRS)
Manges, D. R. (Inventor)
1985-01-01
A cable reel assembly is described which is particularly adapted for, but not limited to, a system for providing electrical connection of power and data signals between an orbiter vehicle, such as a space shuttle, and a recovered satellite. The assembly is comprised of two mutually opposing ring type structures having 180 deg relative rotation with one of the structures being held in fixed position while the other structure is rotatable. Motor controlled berthing latches and umbilical cable connectors for the satellite are located on the rim of the rotatable ring structure. The electrical cable assembly is fed in two sections from the orbiter vehicle into the outer rim portion of the fixed ring structure where they are directed inwardly and attached to two concentrically coiled metal bands whose respective ends are secured to inner and outer post members of circular sets of guide pins located on opposing circular plate members, one rotatable and one fixed. The cable sections are fed out as three output cable sections through openings in the central portion of the circular plate of the rotatable ring structure where they are directed to the latches and connectors located on its rim.
Application of optical 3D measurement on thin film buckling to estimate interfacial toughness
NASA Astrophysics Data System (ADS)
Jia, H. K.; Wang, S. B.; Li, L. A.; Wang, Z. Y.; Goudeau, P.
2014-03-01
The shape-from-focus (SFF) method has been widely studied as a passive depth recovery and 3D reconstruction method for digital images. An important step in SFF is the calculation of the focus level for different points in an image by using a focus measure. In this work, an image entropy-based focus measure is introduced into the SFF method to measure the 3D buckling morphology of an aluminum film on a polymethylmethacrylate (PMMA) substrate at a micro scale. Spontaneous film wrinkles and telephone-cord wrinkles are investigated after the deposition of a 300 nm thick aluminum film onto the PMMA substrate. Spontaneous buckling is driven by the highly compressive stress generated in the Al film during the deposition process. The interfacial toughness between metal films and substrates is an important parameter for the reliability of the film/substrate system. The height profiles of different sections across the telephone-cord wrinkle can be considered a straight-sided model with uniform width and height or a pinned circular model that has a delamination region characterized by a sequence of connected sectors. Furthermore, the telephone-cord geometry of the thin film can be used to calculate interfacial toughness. The instability of the finite element model is introduced to fit the buckling morphology obtained by SFF. The interfacial toughness is determined to be 0.203 J/m2 at a 70.4° phase angle from the straight-sided model and 0.105 J/m2 at 76.9° from the pinned circular model.
Flow boiling with enhancement devices for cold plate coolant channel design
NASA Technical Reports Server (NTRS)
Boyd, Ronald D., Sr.
1989-01-01
A research program to study the effect of enhancement devices on flow boiling heat transfer in coolant channels, which are heated either from the top side or uniformly, is discussed. Freon 11 is the working fluid involved. The specific objectives are: (1) examine the variations in both the mean and local (axial and circumferential) heat transfer coefficients for a circular coolant channel with either smooth walls or with both a twisted tape and spiral finned walls, (2) examine the effect channel diameter (and the length-to-diameter aspect ratio) variations for the smooth wall channel, and (3) develop an improved data reduction analysis.
1970-12-01
a Circular Hole A.S. Kobayashi and D.E. Maiden 217 Fatigue Performance of High Strength An Effective Strain Concept for Steels as Related to Their a ...in AFLC Col. H.B. Morrison, Jr. 899 Results of Analysis, Fatigue Testing and Usage of a High Speed Aircraft Subjected to Combined Peacetime and High ...on the level of the in a recent study of the fatigue performance of some stable elastic limit that can be produced by dislocation pin- high yield
Mode I analysis of a cracked circular disk subject to a couple and a force
NASA Technical Reports Server (NTRS)
Gross, B.
1977-01-01
Mode 1 stress intensity coefficients were obtained for an edge-cracked disk (round compact specimen). Results for this plane elastostatic problem, obtained by a boundary collocation analysis are presented for ratios 0.35 less than A/D less than 1, where A is the crack length and D is the disk diameter. The results presented are for two complementary types of loading. By superposition of these results the stress intensity factor K sub I for any practical load line location of a pin-loaded round compact specimen can be obtained.
NASA Technical Reports Server (NTRS)
Shih, T. I.-P.; Roelke, R. J.; Steinthorsson, E.
1991-01-01
In order to study numerically details of the flow and heat transfer within coolant passages of turbine blades, a method must first be developed to generate grid systems within the very complicated geometries involved. In this study, a grid generation package was developed that is capable of generating the required grid systems. The package developed is based on an algebraic grid generation technique that permits the user considerable control over how grid points are to be distributed in a very explicit way. These controls include orthogonality of grid lines next to boundary surfaces and ability to cluster about arbitrary points, lines, and surfaces. This paper describes that grid generation package and shows how it can be used to generate grid systems within complicated-shaped coolant passages via an example.
Thermoelectric Devices Advance Thermal Management
NASA Technical Reports Server (NTRS)
2007-01-01
Thermoelectric (TE) devices heat, cool, and generate electricity when a temperature differential is provided between the two module faces. In cooperation with NASA, Chico, California-based United States Thermoelectric Consortium Inc. (USTC) built a gas emissions analyzer (GEA) for combustion research. The GEA precipitated hydrocarbon particles, preventing contamination that would hinder precise rocket fuel analysis. The USTC research and design team uses patent-pending dimple, pin-fin, microchannel and microjet structures to develop and design heat dissipation devices on the mini-scale level, which not only guarantee high performance of products, but also scale device size from 1 centimeter to 10 centimeters. USTC continues to integrate the benefits of TE devices in its current line of thermal management solutions and has found the accessibility of NASA technical research to be a valuable, sustainable resource that has continued to positively influence its product design and manufacturing
Fronts and waves of actin polymerization in a bistability-based mechanism of circular dorsal ruffles
NASA Astrophysics Data System (ADS)
Bernitt, Erik; Döbereiner, Hans-Günther; Gov, Nir S.; Yochelis, Arik
2017-06-01
During macropinocytosis, cells remodel their morphologies for the uptake of extracellular matter. This endocytotic mechanism relies on the collapse and closure of precursory structures, which are propagating actin-based, ring-shaped vertical undulations at the dorsal (top) cell membrane, a.k.a. circular dorsal ruffles (CDRs). As such, CDRs are essential to a range of vital and pathogenic processes alike. Here we show, based on both experimental data and theoretical analysis, that CDRs are propagating fronts of actin polymerization in a bistable system. The theory relies on a novel mass-conserving reaction-diffusion model, which associates the expansion and contraction of waves to distinct counter-propagating front solutions. Moreover, the model predicts that under a change in parameters (for example, biochemical conditions) CDRs may be pinned and fluctuate near the cell boundary or exhibit complex spiral wave dynamics due to a wave instability. We observe both phenomena also in our experiments indicating the conditions for which macropinocytosis is suppressed.
Fronts and waves of actin polymerization in a bistability-based mechanism of circular dorsal ruffles
Bernitt, Erik; Döbereiner, Hans-Günther; Gov, Nir S.; Yochelis, Arik
2017-01-01
During macropinocytosis, cells remodel their morphologies for the uptake of extracellular matter. This endocytotic mechanism relies on the collapse and closure of precursory structures, which are propagating actin-based, ring-shaped vertical undulations at the dorsal (top) cell membrane, a.k.a. circular dorsal ruffles (CDRs). As such, CDRs are essential to a range of vital and pathogenic processes alike. Here we show, based on both experimental data and theoretical analysis, that CDRs are propagating fronts of actin polymerization in a bistable system. The theory relies on a novel mass-conserving reaction–diffusion model, which associates the expansion and contraction of waves to distinct counter-propagating front solutions. Moreover, the model predicts that under a change in parameters (for example, biochemical conditions) CDRs may be pinned and fluctuate near the cell boundary or exhibit complex spiral wave dynamics due to a wave instability. We observe both phenomena also in our experiments indicating the conditions for which macropinocytosis is suppressed. PMID:28627511
Tafazal, Suhayl; Madan, Sanjeev S; Ali, Farhan; Padman, Manoj; Swift, Simone; Jones, Stanley; Fernandes, James A
2014-05-01
The use of circular fixators for the treatment of tibial fractures is well established in the literature. The aim of this study was to compare the Ilizarov circular fixator (ICF) with the Taylor spatial frame (TSF) in terms of treatment results in consecutive patients with tibial fractures that required operative management. A retrospective analysis of patient records and radiographs was performed to obtain patient data, information on injury sustained, the operative technique used, time duration in frame, healing time and complications of treatment. The minimum follow-up was 24 months. Ten patients were treated with ICF between 2000 and 2005, while 15 patients have been treated with TSF since 2005. Two of the 10 treated with ICF and 5 of the 15 treated with TSF were open fractures. All patients went on to achieve complete union. Mean duration in the frame was 12.7 weeks for ICF and 14.8 weeks for the TSF group. Two patients in the TSF group had delayed union and required additional procedures including adjustment of fixator and bone grafting. There was one malunion in the TSF group that required osteotomy and reapplication of frame. There were seven and nine pin-site infections in the ICF and TSF groups, respectively, all of which responded to antibiotics. There were no refractures in either group. In an appropriate patient, both types of circular fixator are equally effective but have different characteristics, with TSF allowing for postoperative deformity correction. Of concern are the two cases of delayed union in the TSF group, all in patients with high-energy injuries. We feel another larger study is required to provide further clarity in this matter. Level II-comparative study.
Quasi-stationary phase change heat transfer on a fin
NASA Astrophysics Data System (ADS)
Orzechowski, Tadeusz; Stokowiec, Katarzyna
2016-03-01
The paper presents heat transfer research basing on a long fin with a circular cross-section. Its basis is welded to the pipe where the hot liquid paraffin, having a temperature of 70°C at the inflow, is pumped. The analyzed element is a recurrent part of a refrigeration's condenser, which is immersed in a paraffin. The temperature of the inflowing liquid is higher than the temperature of the melting process for paraffin, which allows the paraffin to liquify. The temperature at the basis of the rib changes and it is assumed that the heat transfer is quasi-stationary. On this basis the estimation of the mean value of heat transfer coefficient was conducted. The unsteady thermal field of the investigated system was registered with an infrared camera V50 produced by a Polish company Vigo System. This device is equipped with a microbolometric detector with 384 × 288 elements and the single pixel size 25 × 25 μm. Their thermal resolution is lower than 70 mK at a temperature of 30 °C. The camera operates at 7,5 ÷ 14 μm long-wave infrared radiation range. For a typical lens 35 mm the special resolution is 0.7 mrad. The result of the calculations is mean heat transfer coefficient for the considered time series. It is equal to 50 W m -2 K-1 and 47 W m -2 K-1 on the left and right side of the fin, respectively. The distance between the experimental data and the curve approximating the temperature distribution was assessed with the standard deviation, Sd = 0.04 K.
Ebert, David A; Haas, Diane L; De Carvalho, Marcelo R
2015-03-19
A new species of torpedo ray, Tetronarce cowleyi, sp. nov., is described from specimens collected from the southeastern Atlantic Ocean. The new species is placed in the genus Tetronarce based on a uniform dorsal coloration and absence of papillae around the spiracles. The new species is distinguished from its closest congeners, the North Atlantic Tetronarce nobiliana Bonnaparte, 1835, and southwestern Atlantic Tetronarce puelcha Lahille, 1926, by a combination of morphological characteristics including a shorter spiracular length, a proportionally greater head length as measured between snout margin and fifth gill openings, a proportionally greater preoral snout length, a uniform shiny black or dark gray dorsal surface, lacking any prominent markings, and a creamy white ventral color with dark edges in juveniles but fading with growth. Teteronarce cowleyi, sp. nov., is further distinguished from T. nobiliana by its more circular anterior disc shape (vs. relatively straight in T. nobiliana), fewer tooth rows (32/28 vs. 38-53/38-52 in T. nobiliana), greater mouth width (1.5-1.7 times as great as interorbital width vs. 0.5-0.6 times interorbital width in T. nobiliana), smaller distance between second dorsal and caudal fins (3.5-4.9% vs. 6.6-6.8% in T. nobiliana), and a clasper length extending nearly to lower caudal fin origin (claspers in T. nobiliana that extend only two-thirds distance between second dorsal and caudal fins). Teteronarce cowleyi, sp. nov., is known from Walvis Bay, Namibia to Algoa Bay, Eastern Cape, South Africa, at depths of 110 to 457 m.
Fundamental Study of Material Flow in Friction Stir Welds
NASA Technical Reports Server (NTRS)
Reynolds, Anthony P.
1999-01-01
The presented research project consists of two major parts. First, the material flow in solid-state, friction stir, butt-welds as been investigated using a marker insert technique. Changes in material flow due to welding parameter as well as tool geometry variations have been examined for different materials. The method provides a semi-quantitative, three-dimensional view of the material transport in the welded zone. Second, a FSW process model has been developed. The fully coupled model is based on fluid mechanics; the solid-state material transport during welding is treated as a laminar, viscous flow of a non-Newtonian fluid past a rotating circular cylinder. The heat necessary for the material softening is generated by deformation of the material. As a first step, a two-dimensional model, which contains only the pin of the FSW tool, has been created to test the suitability of the modeling approach and to perform parametric studies of the boundary conditions. The material flow visualization experiments agree very well with the predicted flow field. Accordingly, material within the pin diameter is transported only in the rotation direction around the pin. Due to the simplifying assumptions inherent in the 2-D model, other experimental data such as forces on the pin, torque, and weld energy cannot be directly used for validation. However, the 2-D model predicts the same trends as shown in the experiments. The model also predicts a deviation from the "normal" material flow at certain combinations of welding parameters, suggesting a possible mechanism for the occurrence of some typical FSW defects. The next step has been the development of a three-dimensional process model. The simplified FSW tool has been designed as a flat shoulder rotating on the top of the workpiece and a rotating, cylindrical pin, which extends throughout the total height of the flow domain. The thermal boundary conditions at the tool and at the contact area to the backing plate have been varied to fit experimental data such as temperature profiles, torque and tool forces. General aspects of the experimentally visualized material flow pattern are confirmed by the 3-D model.
NASA Technical Reports Server (NTRS)
Steinthorsson, E.; Shih, T. I-P.; Roelke, R. J.
1991-01-01
In order to generate good quality systems for complicated three-dimensional spatial domains, the grid-generation method used must be able to exert rather precise controls over grid-point distributions. Several techniques are presented that enhance control of grid-point distribution for a class of algebraic grid-generation methods known as the two-, four-, and six-boundary methods. These techniques include variable stretching functions from bilinear interpolation, interpolating functions based on tension splines, and normalized K-factors. The techniques developed in this study were incorporated into a new version of GRID3D called GRID3D-v2. The usefulness of GRID3D-v2 was demonstrated by using it to generate a three-dimensional grid system in the coolent passage of a radial turbine blade with serpentine channels and pin fins.
Wind tunnel investigation of simulated helicopter engine exhaust interacting with windstream
NASA Technical Reports Server (NTRS)
Shaw, C. S.; Wilson, J. C.
1974-01-01
A wind tunnel investigation of the windstream-engine exhaust flow interaction on a light observation helicopter model has been conducted in the Langley V/STOL tunnel. The investigation utilized flow visualization techniques to determine the cause to determine the cause of exhaust shield overheating during cruise and to find a means of eliminating the problem. Exhaust flow attachment to the exhaust shield during cruise was found to cause the overheating. Several flow-altering devices were evaluated to find a suitable way to correct the problem. A flow deflector located on the model cowling upstream of the exhaust in addition to aerodynamic shield fairings provided the best solution. Also evaluated was heat transfer concept employing pin fins to cool future exhaust hardware. The primary flow visualization technique used in the investigation was a newly developed system employing neutrally buoyant helium-filled bubbles. The resultant flow patterns were recorded on motion picture film and on television magnetic tape.
Di Domenico, Giovanni; Cardarelli, Paolo; Contillo, Adriano; Taibi, Angelo; Gambaccini, Mauro
2016-01-01
The quality of a radiography system is affected by several factors, a major one being the focal spot size of the x-ray tube. In fact, the measurement of such size is recognized to be of primary importance during acceptance tests and image quality evaluations of clinical radiography systems. The most common device providing an image of the focal spot emission distribution is a pin-hole camera, which requires a high tube loading in order to produce a measurable signal. This work introduces an alternative technique to obtain an image of the focal spot, through the processing of a single radiograph of a simple test object, acquired with a suitable magnification. The radiograph of a magnified sharp edge is a well-established method to evaluate the extension of the focal spot profile along the direction perpendicular to the edge. From a single radiograph of a circular x-ray absorber, it is possible to extract simultaneously the radial profiles of several sharp edges with different orientations. The authors propose a technique that allows to obtain an image of the focal spot through the processing of these radial profiles by means of a pseudo-CT reconstruction technique. In order to validate this technique, the reconstruction has been applied to the simulated radiographs of an ideal disk-shaped absorber, generated by various simulated focal spot distributions. Furthermore, the method has been applied to the focal spot of a commercially available mammography unit. In the case of simulated radiographs, the results of the reconstructions have been compared to the original distributions, showing an excellent agreement for what regards both the overall distribution and the full width at half maximum measurements. In the case of the experimental test, the method allowed to obtain images of the focal spot that have been compared with the results obtained through standard techniques, namely, pin-hole camera and slit camera. The method was proven to be effective for simulated images and the results of the experimental test suggest that it could be considered as an alternative technique for focal spot distribution evaluation. The method offers the possibility to measure the actual focal spot size and emission distribution at the same exposure conditions as clinical routine, avoiding high tube loading as in the case of the pin-hole imaging technique.
Oceanic Sharks Clean at Coastal Seamount
Oliver, Simon P.; Hussey, Nigel E.; Turner, John R.; Beckett, Alison J.
2011-01-01
Interactions between pelagic thresher sharks (Alopias pelagicus) and cleaner wrasse were investigated at a seamount in the Philippines. Cleaning associations between sharks and teleosts are poorly understood, but the observable interactions seen at this site may explain why these mainly oceanic sharks regularly venture into shallow coastal waters where they are vulnerable to disturbance from human activity. From 1,230 hours of observations recorded by remote video camera between July 2005 and December 2009, 97 cleaner-thresher shark events were analyzed, 19 of which were interrupted. Observations of pelagic thresher sharks interacting with cleaners at the seamount were recorded at all times of day but their frequency declined gradually from morning until evening. Cleaners showed preferences for foraging on specific areas of a thresher shark's body. For all events combined, cleaners were observed to conduct 2,757 inspections, of which 33.9% took place on the shark's pelvis, 23.3% on the pectoral fins, 22.3% on the caudal fin, 8.6% on the body, 8.3% on the head, 2.1% on the dorsal fin, and 1.5% on the gills respectively. Cleaners did not preferentially inspect thresher sharks by time of day or by shark sex, but there was a direct correlation between the amount of time a thresher shark spent at a cleaning station and the number of inspections it received. Thresher shark clients modified their behavior by “circular-stance-swimming,” presumably to facilitate cleaner inspections. The cleaner-thresher shark association reflected some of the known behavioral trends in the cleaner-reef teleost system since cleaners appeared to forage selectively on shark clients. Evidence is mounting that in addition to acting as social refuges and foraging grounds for large visiting marine predators, seamounts may also support pelagic ecology by functioning as cleaning stations for oceanic sharks and rays. PMID:21423796
Stability Design and Response to Waves by Batoids.
Fish, Frank E; Hoffman, Jessica L
2015-10-01
Unsteady flows in the marine environment can affect the stability and locomotor costs of animals. For fish swimming at shallow depths, waves represent a form of unsteady flow. Waves consist of cyclic oscillations, during which the water moves in circular or elliptical orbits. Large gravity waves have the potential to displace fish both cyclically and in the direction of wave celerity for animals floating in the water column or holding station on the bottom. Displacement of a fish can exceed its stability control capability when the size of the wave orbit is equivalent to the size of the fish. Previous research into compensatory behaviors of fishes to waves has focused on pelagic osteichthyan fishes with laterally compressed bodies. However, dorsoventrally compressed batoid rays must also contend with waves. Examination of rays subjected to waves showed differing strategies for stability between pelagic and demersal species. Pelagic cownose rays (Rhinoptera bonasus) would glide through or be transported by waves, maintaining a positive dihedral of the wing-like pectoral fins. Demersal Atlantic stingrays (Dasyatis sabina) and freshwater rays (Potamotrygon motoro) maintained contact with the bottom and performed compensatory fin motions and body postures. The ability to limit displacement due to wave action by the demersal rays was also a function of the bottom texture. The ability of rays to maintain stability due to wave action suggests mechanisms to compensate for the velocity flux of the water impinging on the large projected area of the enlarged pectoral fins of rays. © The Author 2015. Published by Oxford University Press on behalf of the Society for Integrative and Comparative Biology. All rights reserved. For permissions please email: journals.permissions@oup.com.
Gong, Zhi-Cheng; Huang, Qiong; Dai, Xing-Ping; Lei, Guang-Hua; Lu, Hong-Bin; Yin, Ji-Ye; Xu, Xiao-Jing; Qu, Jian; Pei, Qi; Dong, Min; Zhou, Bo-Ting; Shen, Jie; Zhou, Gan; Zhou, Hong-Hao; Liu, Zhao-Qian
2012-01-01
AIMS We aimed to determine whether NeuroD1/BETA2 and PAX4 polymorphisms were associated with the therapeutic efficacy of repaglinide in Chinese type 2 diabetes mellitus (T2DM) patients. METHODS Three hundred and sixty-eight T2DM patients and 132 healthy control subjects were genotyped by restriction fragment length polymorphism. Forty-three patients with various genotypes were randomly selected to undergo 8 weeks of repaglinide treatment (3 mg day−1). Fasting plasma glucose, postprandial plasma glucose, glycated haemoglobin, fasting and postprandial serum insulin (FINS, PINS), homeostasis model assessment for insulin resistance, serum triglyceride, total cholesterol, low-density lipoprotein-cholesterol and high-density lipoprotein-cholesterol were determined before and after repaglinide treatment. RESULTS The allelic frequency of NeuroD1/BETA2 T45 was higher in T2DM patients than in the control subjects [13.45 vs. 6.82%, P < 0.01, odds ratios = 2.342 (1.365, 4.019), P= 0.002]. Type 2 diabetes mellitus patients with the mutated allele of NeuroD1/BETA2 A45T polymorphism showed higher FINS (13.46 ± 12.57 vs. 10.04 ± 7.09 mU l−1, P < 0.05) (11.67, 14.83 vs. 8.38, 11.37) and PINS (52.11 ± 40.93 vs. 68.66 ± 43.87 mU l−1, P < 0.05) (44.89, 58.35 vs. 55.35, 88.87) than individuals with the T allele. The PAX4 R121W R allele carriers had higher PINS (52.11 ± 40.93 vs. 68.66 ± 43.87 mU l−1, P < 0.05) (44.89, 58.35 vs. 55.35, 88.87) than subjects with the W allele. After repaglinide treatment, patients with the T allele of NeuroD1/BETA2 A45T polymorphisms had attenuated efficacy on fasting plasma glucose (−2.79 ± 2.14 vs.−0.99 ± 1.80 mmol l−1, P < 0.01) (−3.53, −1.84 vs.−1.99, −0.13) and postprandial plasma glucose (−6.71 ± 5.90 vs.−2.54 ± 3.39 mmol l−1, P < 0.01) (−9.28, −4.62 vs.−4.34, −0.84). Patients with the RR genotype of PAX4 R121W showed better efficacy with respect to the level of postprandial plasma glucose than R/W genotypes (−6.53 ± 6.52 vs.−2.95 ± 1.17 mmol l−1, P < 0.05) (−8.20, −4.89 vs.−3.92, −1.20). CONCLUSIONS The NeuroD1/BETA2 and PAX4 polymorphisms were substantially associated with plasma glucose level after repaglinide monotherapy. PMID:22296034
Gong, Zhi-Cheng; Huang, Qiong; Dai, Xing-Ping; Lei, Guang-Hua; Lu, Hong-Bin; Yin, Ji-Ye; Xu, Xiao-Jing; Qu, Jian; Pei, Qi; Dong, Min; Zhou, Bo-Ting; Shen, Jie; Zhou, Gan; Zhou, Hong-Hao; Liu, Zhao-Qian
2012-09-01
We aimed to determine whether NeuroD1/BETA2 and PAX4 polymorphisms were associated with the therapeutic efficacy of repaglinide in Chinese type 2 diabetes mellitus (T2DM) patients. Three hundred and sixty-eight T2DM patients and 132 healthy control subjects were genotyped by restriction fragment length polymorphism. Forty-three patients with various genotypes were randomly selected to undergo 8 weeks of repaglinide treatment (3 mg day(-1)). Fasting plasma glucose, postprandial plasma glucose, glycated haemoglobin, fasting and postprandial serum insulin (FINS, PINS), homeostasis model assessment for insulin resistance, serum triglyceride, total cholesterol, low-density lipoprotein-cholesterol and high-density lipoprotein-cholesterol were determined before and after repaglinide treatment. The allelic frequency of NeuroD1/BETA2 T45 was higher in T2DM patients than in the control subjects [13.45 vs. 6.82%, P < 0.01, odds ratios = 2.342 (1.365, 4.019), P= 0.002]. Type 2 diabetes mellitus patients with the mutated allele of NeuroD1/BETA2 A45T polymorphism showed higher FINS (13.46 ± 12.57 vs. 10.04 ± 7.09 mU l(-1) , P < 0.05) (11.67, 14.83 vs. 8.38, 11.37) and PINS (52.11 ± 40.93 vs. 68.66 ± 43.87 mU l(-1), P < 0.05) (44.89, 58.35 vs. 55.35, 88.87) than individuals with the T allele. The PAX4 R121W R allele carriers had higher PINS (52.11 ± 40.93 vs. 68.66 ± 43.87 mU l(-1), P < 0.05) (44.89, 58.35 vs. 55.35, 88.87) than subjects with the W allele. After repaglinide treatment, patients with the T allele of NeuroD1/BETA2 A45T polymorphisms had attenuated efficacy on fasting plasma glucose (-2.79 ± 2.14 vs.-0.99 ± 1.80 mmol l(-1), P < 0.01) (-3.53, -1.84 vs.-1.99, -0.13) and postprandial plasma glucose (-6.71 ± 5.90 vs.-2.54 ± 3.39 mmol l(-1), P < 0.01) (-9.28, -4.62 vs.-4.34, -0.84). Patients with the RR genotype of PAX4 R121W showed better efficacy with respect to the level of postprandial plasma glucose than R/W genotypes (-6.53 ± 6.52 vs.-2.95 ± 1.17 mmol l(-1), P < 0.05) (-8.20, -4.89 vs.-3.92, -1.20). The NeuroD1/BETA2 and PAX4 polymorphisms were substantially associated with plasma glucose level after repaglinide monotherapy. © 2012 The Authors. British Journal of Clinical Pharmacology © 2012 The British Pharmacological Society.
Formability analysis of austenitic stainless steel-304 under warm conditions
NASA Astrophysics Data System (ADS)
Lade, Jayahari; Singh, Swadesh Kumar; Banoth, Balu Naik; Gupta, Amit Kumar
2013-12-01
A warm deep drawing process of austenitic stainless steel-304 (ASS-304) of circular blanks with coupled ther mal analysis is studied in this article. 65 mm blanks were deep drawn at different temperatures and thickness distribution is experimentally measured after cutting the drawn component into two halves. The process is simulated using explicit fin ite element code LS-DYNA. A Barlat 3 parameter model is used in the simulation, as the material is anisotropic up to 30 0°C. Material properties for the simulation are determined at different temperatures using a 5 T UTM coupled with a furn ace. In this analysis constant punch speed and variable blank holder force (BHF) is applied to draw cups without wrinkle.
Flow in the Proximity of the Pin-Tool in Friction Stir Welding and Its Relation to Weld Homogeneity
NASA Technical Reports Server (NTRS)
Nunes, Arthur C., Jr.
2000-01-01
In the Friction Stir Welding (FSW) process a rotating pin inserted into a seam literally stirs the metal from each side of the seam together. It is proposed that the flow in the vicinity of the pin-tool comprises a primary rapid shear over a cylindrical envelope covering the pin-tool and a relatively slow secondary flow taking the form of a ring vortex about the tool circumference. This model is consistent with a plastic characterization of metal flow, where discontinuities in shear flow are allowed but not viscous effects. It is consistent with experiments employing several different kinds of tracer: atomic markers, shot, and wire. If a rotating disc with angular velocity w is superposed on a translating continuum with linear velocity omega, the trajectories of tracer points become circular arcs centered upon a point displaced laterally a distance v/omega from the center of rotation of the disc in the direction of the advancing side of the disc. In the present model a stream of metal approaching the tool (taken as the coordinate system of observation) is sheared at the slip surface, rapidly rotated around the tool, sheared again on the opposite side of the tool, and deposited in the wake of the tool. Local shearing rates are high, comparable to metal cutting in this model. The flow patterns in the vicinity of the pin-tool determine the level of homogenization and dispersal of contaminants that occurs in the FSW process. The approaching metal streams enfold one another as they are rotated around the tool. Neglecting mixing they return to the same lateral position in the wake of the tool preserving lateral tracer positions as if the metal had flowed past the tool like an extrusion instead of being rotated around it. (The seam is, however, obliterated.) The metal stream of thickness approximately that of the tool diameter D is wiped past the tool at elevated temperatures drawn out to a thickness of v/2(omega) in the wiping zone. Mixing distances in the wiping zone are multiplied in the unfolded metal. Inhomogeneities on a smaller scale than the mixing length are obliterated, but structure on a larger scale may be transmitted to the wake of a FSW weld.
Structural features of diverse Pin-II proteinase inhibitor genes from Capsicum annuum.
Mahajan, Neha S; Dewangan, Veena; Lomate, Purushottam R; Joshi, Rakesh S; Mishra, Manasi; Gupta, Vidya S; Giri, Ashok P
2015-02-01
The proteinase inhibitor (PI) genes from Capsicum annuum were characterized with respect to their UTR, introns and promoter elements. The occurrence of PIs with circularly permuted domain organization was evident. Several potato inhibitor II (Pin-II) type proteinase inhibitor (PI) genes have been analyzed from Capsicum annuum (L.) with respect to their differential expression during plant defense response. However, complete gene characterization of any of these C. annuum PIs (CanPIs) has not been carried out so far. Complete gene architectures of a previously identified CanPI-7 (Beads-on-string, Type A) and a member of newly isolated Bracelet type B, CanPI-69 are reported in this study. The 5' UTR (untranslated region), 3'UTR, and intronic sequences of both the CanPI genes were obtained. The genomic sequence of CanPI-7 exhibited, exon 1 (49 base pair, bp) and exon 2 (740 bp) interrupted by a 294-bp long type I intron. We noted the occurrence of three multi-domain PIs (CanPI-69, 70, 71) with circularly permuted domain organization. CanPI-69 was found to possess exon 1 (49 bp), exon 2 (551 bp) and a 584-bp long type I intron. The upstream sequence analysis of CanPI-7 and CanPI-69 predicted various transcription factor-binding sites including TATA and CAAT boxes, hormone-responsive elements (ABRELATERD1, DOFCOREZM, ERELEE4), and a defense-responsive element (WRKY71OS). Binding of transcription factors such as zinc finger motif MADS-box and MYB to the promoter regions was confirmed using electrophoretic mobility shift assay followed by mass spectrometric identification. The 3' UTR analysis for 25 CanPI genes revealed unique/distinct 3' UTR sequence for each gene. Structures of three domain CanPIs of type A and B were predicted and further analyzed for their attributes. This investigation of CanPI gene architecture will enable the better understanding of the genetic elements present in CanPIs.
NASA Technical Reports Server (NTRS)
Faulkner, F. E.
1971-01-01
A study was conducted to determine the effect of chord size on air cooled turbine blades. In the preliminary design phase, eight turbine blade cooling configurations in 0.75-in., 1.0-in., and 1.5-in. chord sizes were analyzed to determine the maximum turbine inlet temperature capabilities. A pin fin convection cooled configuration and a film-impingement cooled configuration were selected for a final design analysis in which the maximum turbine inlet temperature was determined as a function of the cooling air inlet temperature and the turbine inlet total pressure for each of the three chord sizes. The cooling air flow requirements were also determined for a varying cooling air inlet temperature with a constant turbine inlet temperature. It was determined that allowable turbine inlet temperature increases with increasing chord for the convection cooled and transpiration cooled designs, however, the film-convection cooled designs did not have a significant change in turbine inlet temperature with chord.
NASA Technical Reports Server (NTRS)
Dubiel, D. J.; Lohmann, R. P.; Tanrikut, S.; Morris, P. M.
1986-01-01
Under the NASA-sponsored Energy Efficient Engine program, Pratt and Whitney has successfully completed a comprehensive test program using a 90-degree sector combustor rig that featured an advanced two-stage combustor with a succession of advanced segmented liners. Building on the successful characteristics of the first generation counter-parallel Finwall cooled segmented liner, design features of an improved performance metallic segmented liner were substantiated through representative high pressure and temperature testing in a combustor atmosphere. This second generation liner was substantially lighter and lower in cost than the predecessor configuration. The final test in this series provided an evaluation of ceramic composite liner segments in a representative combustor environment. It was demonstrated that the unique properties of ceramic composites, low density, high fracture toughness, and thermal fatigue resistance can be advantageously exploited in high temperature components. Overall, this Combustor Section Rig Test program has provided a firm basis for the design of advanced combustor liners.
NASA Astrophysics Data System (ADS)
Vasoya, Manish; Lazarus, Véronique; Ponson, Laurent
2016-10-01
The effect of strong toughness heterogeneities on the macroscopic failure properties of brittle solids is investigated in the context of planar crack propagation. The basic mechanism at play is that the crack is locally slowed down or even trapped when encountering tougher material. The induced front deformation results in a selection of local toughness values that reflect at larger scale on the material resistance. To unravel this complexity and bridge micro to macroscale in failure of strongly heterogeneous media, we propose a homogenization procedure based on the introduction of two complementary macroscopic properties: An apparent toughness defined from the loading required to make the crack propagate and an effective fracture energy defined from the rate of energy released by unit area of crack advance. The relationship between these homogenized properties and the features of the local toughness map is computed using an iterative perturbation method. This approach is applied to a circular crack pinned by a periodic array of obstacles invariant in the radial direction, which gives rise to two distinct propagation regimes: A weak pinning regime where the crack maintains a stationary shape after reaching an equilibrium position and a fingering regime characterized by the continuous growth of localized regions of the fronts while the other parts remain trapped. Our approach successfully bridges micro to macroscopic failure properties in both cases and illustrates how small scale heterogeneities can drastically affect the overall failure response of brittle solids. On a broader perspective, we believe that our approach can be used as a powerful tool for the rational design of heterogeneous brittle solids and interfaces with tailored failure properties.
NASA Technical Reports Server (NTRS)
Weddendorf, Bruce C. (Inventor)
1994-01-01
An artificial, manually positionable elbow joint for use in an upper extremity, above-elbow, prosthetic is described. The prosthesis provides a locking feature that is easily controlled by the wearer. The instant elbow joint is very strong and durable enough to withstand the repeated heavy loadings encountered by a wearer who works in an industrial, construction, farming, or similar environment. The elbow joint of the present invention comprises a turntable, a frame, a forearm, and a locking assembly. The frame generally includes a housing for the locking assembly and two protruding ears. The forearm includes an elongated beam having a cup-shaped cylindrical member at one end and a locking wheel having a plurality of holes along a circular arc on its other end with a central bore for pivotal attachment to the protruding ears of the frame. The locking assembly includes a collar having a central opening with a plurality of internal grooves, a plurality of internal cam members each having a chamfered surface at one end and a V-shaped slot at its other end; an elongated locking pin having a crown wheel with cam surfaces and locking lugs secured thereto; two coiled compression springs; and a flexible filament attached to one end of the elongated locking pin and extending from the locking assembly for extending and retracting the locking pin into the holes in the locking wheel to permit selective adjustment of the forearm relative to the frame. In use, the turntable is affixed to the upper arm part of the prosthetic in the conventional manner, and the cup-shaped cylindrical member on one end of the forearm is affixed to the forearm piece of the prosthetic in the conventional manner. The elbow joint is easily adjusted and locked between maximum flex and extended positions.
Helicity Asymmetry in gamma p -> pi+ n with FROST
DOE Office of Scientific and Technical Information (OSTI.GOV)
Steffen Strauch
2012-04-01
The main objective of the FROST experiment at Jefferson Lab is the study of baryon resonances. The polarization observable E for the reaction gamma p to pi+n has been measured as part of this program. A circularly polarized tagged photon beam with energies from 0.35 to 2.35 GeV was incident on a longitudinally polarized frozen-spin butanol target. The final-state pions were detected with the CEBAF Large Acceptance Spectrometer. Preliminary polarization data agree fairly well with present SAID and MAID partial-wave analyses at low photon energies. In most of the covered energy range, however, significant deviations are observed. These discrepancies underlinemore » the crucial importance of polarization observables to further constrain these analyses.« less
Sun, Mingui; Burke, Lora E.; Baranowski, Thomas; Fernstrom, John D.; Zhang, Hong; Chen, Hsin-Chen; Bai, Yicheng; Li, Yuecheng; Li, Chengliu; Yue, Yaofeng; Li, Zhen; Nie, Jie; Sclabassi, Robert J.; Mao, Zhi-Hong; Jia, Wenyan
2015-01-01
Recently, wearable computers have become new members in the family of mobile electronic devices, adding new functions to those provided by smartphones and tablets. As “always-on” miniature computers in the personal space, they will play increasing roles in the field of healthcare. In this work, we present our development of eButton, a wearable computer designed as a personalized, attractive, and convenient chest pin in a circular shape. It contains a powerful microprocessor, numerous electronic sensors, and wireless communication links. We describe its design concepts, electronic hardware, data processing algorithms, and its applications to the evaluation of diet, physical activity and lifestyle in the study of obesity and other chronic diseases. PMID:25708374
Sun, Mingui; Burke, Lora E; Baranowski, Thomas; Fernstrom, John D; Zhang, Hong; Chen, Hsin-Chen; Bai, Yicheng; Li, Yuecheng; Li, Chengliu; Yue, Yaofeng; Li, Zhen; Nie, Jie; Sclabassi, Robert J; Mao, Zhi-Hong; Jia, Wenyan
2015-01-01
Recently, wearable computers have become new members in the family of mobile electronic devices, adding new functions to those provided by smart-phones and tablets. As "always-on" miniature computers in the personal space, they will play increasing roles in the field of healthcare. In this work, we present our development of eButton, a wearable computer designed as a personalized, attractive, and convenient chest pin in a circular shape. It contains a powerful microprocessor, numerous electronic sensors, and wireless communication links. We describe its design concepts, electronic hardware, data processing algorithms, and its applications to the evaluation of diet, physical activity and lifestyle in the study of obesity and other chronic diseases.
Mechanosensation in an adipose fin
2016-01-01
Adipose fins are found on approximately 20% of ray-finned fish species. The apparently rudimentary anatomy of adipose fins inspired a longstanding hypothesis that these fins are vestigial and lack function. However, adipose fins have evolved repeatedly within Teleostei, suggesting adaptive function. Recently, adipose fins were proposed to function as mechanosensors, detecting fluid flow anterior to the caudal fin. Here we test the hypothesis that adipose fins are mechanosensitive in the catfish Corydoras aeneus. Neural activity, recorded from nerves that innervate the fin, was shown to encode information on both movement and position of the fin membrane, including the magnitude of fin membrane displacement. Thus, the adipose fin of C. aeneus is mechanosensitive and has the capacity to function as a ‘precaudal flow sensor’. These data force re-evaluation of adipose fin clipping, a common strategy for tagging fishes, and inform hypotheses of how function evolves in novel vertebrate appendages. PMID:26984621
Mechanosensation in an adipose fin.
Aiello, Brett R; Stewart, Thomas A; Hale, Melina E
2016-03-16
Adipose fins are found on approximately 20% of ray-finned fish species. The apparently rudimentary anatomy of adipose fins inspired a longstanding hypothesis that these fins are vestigial and lack function. However, adipose fins have evolved repeatedly within Teleostei, suggesting adaptive function. Recently, adipose fins were proposed to function as mechanosensors, detecting fluid flow anterior to the caudal fin. Here we test the hypothesis that adipose fins are mechanosensitive in the catfish Corydoras aeneus. Neural activity, recorded from nerves that innervate the fin, was shown to encode information on both movement and position of the fin membrane, including the magnitude of fin membrane displacement. Thus, the adipose fin of C. aeneus is mechanosensitive and has the capacity to function as a 'precaudal flow sensor'. These data force re-evaluation of adipose fin clipping, a common strategy for tagging fishes, and inform hypotheses of how function evolves in novel vertebrate appendages. © 2016 The Author(s).
Stewart, Thomas A; Smith, W Leo; Coates, Michael I
2014-04-22
Adipose fins are appendages found on the dorsal midline between the dorsal and caudal fins in more than 6000 living species of teleost fishes. It has been consistently argued that adipose fins evolved once and have been lost repeatedly across teleosts owing to limited function. Here, we demonstrate that adipose fins originated repeatedly by using phylogenetic and anatomical evidence. This suggests that adipose fins are adaptive, although their function remains undetermined. To test for generalities in the evolution of form in de novo vertebrate fins, we studied the skeletal anatomy of adipose fins across 620 species belonging to 186 genera and 55 families. Adipose fins have repeatedly evolved endoskeletal plates, anterior dermal spines and fin rays. The repeated evolution of fin rays in adipose fins suggests that these fins can evolve new tissue types and increased structural complexity by expressing fin-associated developmental modules in these new territories. Patterns of skeletal elaboration differ between the various occurrences of adipose fins and challenge prevailing hypotheses for vertebrate fin origin. Adipose fins represent a powerful and, thus far, barely studied model for exploring the evolution of vertebrate limbs and the roles of adaptation and generative biases in morphological evolution.
Stewart, Thomas A.; Smith, W. Leo; Coates, Michael I.
2014-01-01
Adipose fins are appendages found on the dorsal midline between the dorsal and caudal fins in more than 6000 living species of teleost fishes. It has been consistently argued that adipose fins evolved once and have been lost repeatedly across teleosts owing to limited function. Here, we demonstrate that adipose fins originated repeatedly by using phylogenetic and anatomical evidence. This suggests that adipose fins are adaptive, although their function remains undetermined. To test for generalities in the evolution of form in de novo vertebrate fins, we studied the skeletal anatomy of adipose fins across 620 species belonging to 186 genera and 55 families. Adipose fins have repeatedly evolved endoskeletal plates, anterior dermal spines and fin rays. The repeated evolution of fin rays in adipose fins suggests that these fins can evolve new tissue types and increased structural complexity by expressing fin-associated developmental modules in these new territories. Patterns of skeletal elaboration differ between the various occurrences of adipose fins and challenge prevailing hypotheses for vertebrate fin origin. Adipose fins represent a powerful and, thus far, barely studied model for exploring the evolution of vertebrate limbs and the roles of adaptation and generative biases in morphological evolution. PMID:24598422
Stewart, Thomas A.; Hale, Melina E.
2013-01-01
Adipose fins are enigmatic appendages found between the dorsal and caudal fins of some teleostean fishes. Long thought to be vestigial, degenerate second dorsal fins, remnants of the primitive gnathostome condition, adipose fins have since been recognized as novel morphologies. Unique among the fins of extant fishes, adipose fins have uniformly been described as passive structures, with no associated musculature. Here we provide the first description of a musculoskeletal linkage in an adipose fin, identified in the sun catfish Horabagrus brachysoma. Modified supracarinalis posterior muscles insert from the dorsal midline anterior to the adipose fin by tendons onto the fin base. An additional pair of posterior adipose-fin muscles also inserts upon the fin base and lay posterolateral to the fin, superficial to the axial muscle. This musculoskeletal linkage is an evolutionary innovation, a novel mechanism for controlling adipose-fin movement. These muscles appear to exemplify two approaches by which fins evolve to be actively controlled. We hypothesize that the anterior muscles arose through co-option of an existing fin linkage, while the posterior muscles originated as de novo fin muscles. These findings present adipose fins as a rich system within which to explore the evolution of novel vertebrate appendages. PMID:23135670
Fish locomotion: kinematics and hydrodynamics of flexible foil-like fins
NASA Astrophysics Data System (ADS)
Lauder, George V.; Madden, Peter G. A.
2007-11-01
The fins of fishes are remarkable propulsive devices that appear at the origin of fishes about 500 million years ago and have been a key feature of fish evolutionary diversification. Most fish species possess both median (midline) dorsal, anal, and caudal fins as well as paired pectoral and pelvic fins. Fish fins are supported by jointed skeletal elements, fin rays, that in turn support a thin collagenous membrane. Muscles at the base of the fin attach to and actuate each fin ray, and fish fins thus generate their own hydrodynamic wake during locomotion, in addition to fluid motion induced by undulation of the body. In bony fishes, the jointed fin rays can be actively deformed and the fin surface can thus actively resist hydrodynamic loading. Fish fins are highly flexible, exhibit considerable deformation during locomotion, and can interact hydrodynamically during both propulsion and maneuvering. For example, the dorsal and anal fins shed a vortex wake that greatly modifies the flow environment experienced by the tail fin. New experimental kinematic and hydrodynamic data are presented for pectoral fin function in bluegill sunfish. The highly flexible sunfish pectoral fin moves in a complex manner with two leading edges, a spanwise wave of bending, and substantial changes in area through the fin beat cycle. Data from scanning particle image velocimetry (PIV) and time-resolved stereo PIV show that the pectoral fin generates thrust throughout the fin beat cycle, and that there is no time of net drag. Continuous thrust production is due to fin flexibility which enables some part of the fin to generate thrust at all times and to smooth out oscillations that might arise at the transition from outstroke to instroke during the movement cycle. Computational fluid dynamic analyses of sunfish pectoral fin function corroborate this conclusion. Future research on fish fin function will benefit considerably from close integration with studies of robotic model fins.
Fin development in stream- and hatchery-reared Atlantic salmon
Pelis, Ryan M.; McCormick, S.D.
2003-01-01
To determine the effect of development and environment on fin growth, we measured fin lengths of juvenile Atlantic salmon (Salmo salar) from two hatcheries (August, October and April-May), stream-reared fish (July and October) stocked as fry into two tributaries, and smelts from the main stem of the Connecticut River (May). For stream-reared parr, there was a linear relationship between the dorsal, caudal and anal fins with fork length, while the pectoral, pelvic and adipose fins exhibited a curvilinear relationship with fork length. Parr from a high gradient stream had larger caudal fins than fish from a low gradient stream, but other fins did not differ. Regression lines for the fins of stream-reared smelts were all linear when fin length was regressed against fork length. Stream-reared parr had larger pectoral, pelvic and anal fins than smolts of similar size while dorsal and caudal fin lengths did not differ. Regression equations formulated using the fins of stream-reared parr were used to calculate the percent difference (100 x observed fin length/expected) in fin lengths between stream- and hatchery-reared parr. The pelvic, adipose, caudal and anal fins of hatchery-reared parr showed no signs of degeneration by the first sampling period 7 months after hatching, whereas degeneration in the pectoral (13-20%) and dorsal (15-18%) fins was evident at this time. By the end of the study, degeneration was present in every fin except the adipose, with the pectoral (35-65%) and dorsal (32-58%) fins exhibiting the greatest amount of fin loss. All fins of hatchery-reared parr became shorter with time. There were minor differences in fin degeneration among parr from the two hatcheries, but the overall pattern of decreasing fin size was similar, indicating a common cause of fin degeneration. Comparison of stream- and hatchery-reared fish is a valuable means of determining the impact of captive environments on fin growth.
NASA Astrophysics Data System (ADS)
Wang, Xiao-Hu; Ni, Jian-Shu; Cao, Nai-Long; Yu, Song; Chen, Yi-Gang; Zhang, Shao-Xiang; Gu, Bao-Jun; Yan, Jun
2017-03-01
There is a great clinical need for biodegradable materials, which were used as pins of circular staplers, for gastrointestinal reconstruction in medicine. In this work we compared the effects of the Mg-6Zn and the titanium alloys on collagen metabolism in the healing of the intestinal tract in vivo. The study included Sprague-Dawley rats and their effect was compared on rat’s intestinal tract, using serum magnesium, radiology, and immunohistochemistry in vivo. Radiographic and scanning electron microscope evaluation confirmed the degradation by Mg-6Zn alloy during the implantation period. Biochemical measurements including serum magnesium, creatinine, blood urea nitrogen and glutamic-pyruvic-transaminase proved that degradation of Mg-6Zn alloy showed no impact on serum magnesium and the function of other important organs. Superior to titanium alloy, Mg-6Zn alloy enhanced the expression of collagen I/III and relatively suppressed the expression of MMP-1/-13 in the healing tissues, leading to more mature collagen formation at the site of anastomosis. In conclusion, Mg-6Zn alloy performed better than titanium alloy on collagen metabolism and promoted the healing of intestinal anastomosis. Hence, Mg-6Zn may be a promising candidate for use of stapler pins for intestinal reconstruction in the clinically.
Automatic firearm class identification from cartridge cases
NASA Astrophysics Data System (ADS)
Kamalakannan, Sridharan; Mann, Christopher J.; Bingham, Philip R.; Karnowski, Thomas P.; Gleason, Shaun S.
2011-03-01
We present a machine vision system for automatic identification of the class of firearms by extracting and analyzing two significant properties from spent cartridge cases, namely the Firing Pin Impression (FPI) and the Firing Pin Aperture Outline (FPAO). Within the framework of the proposed machine vision system, a white light interferometer is employed to image the head of the spent cartridge cases. As a first step of the algorithmic procedure, the Primer Surface Area (PSA) is detected using a circular Hough transform. Once the PSA is detected, a customized statistical region-based parametric active contour model is initialized around the center of the PSA and evolved to segment the FPI. Subsequently, the scaled version of the segmented FPI is used to initialize a customized Mumford-Shah based level set model in order to segment the FPAO. Once the shapes of FPI and FPAO are extracted, a shape-based level set method is used in order to compare these extracted shapes to an annotated dataset of FPIs and FPAOs from varied firearm types. A total of 74 cartridge case images non-uniformly distributed over five different firearms are processed using the aforementioned scheme and the promising nature of the results (95% classification accuracy) demonstrate the efficacy of the proposed approach.
In vitro tests of substitute lubricants for wear testing orthopaedic biomaterials.
Scholes, Susan C; Joyce, Thomas J
2013-06-01
Bovine serum is the lubricant recommended by several international standards for the wear testing of orthopaedic biomaterials; however, there are issues over its use due to batch variation, degradation, cost and safety. For these reasons, alternative lubricants were investigated. A 50-station Super-CTPOD (circularly translating pin-on-disc) wear test rig was used, which applied multidirectional motion to ultra-high-molecular-weight polyethylene test pins rubbing against cobalt chromium discs. Thirteen possible alternative lubricants were tested. The use of soy protein as a lubricant gave statistically higher wear, while soya oil, olive oil, Channel Island milk, whole milk, whey, wheatgerm oil, 11 mg/mL egg white, albumin/globulin mix and albumin/globulin/chondroitin sulphate mix all gave statistically lower wear than bovine serum. The lubricants giving the closest wear results to bovine serum were 20 and 40 mg/mL egg white solutions. A light absorbance assay found that these egg white solutions suffered from a high degradation rate that increased with increasing protein content. While egg white solutions offer the best alternative lubricant to bovine serum due to the wear volumes produced, cost-effectiveness and safety of handling, protein degradation will still occur, leading to the need for regular lubricant replacement. Of the lubricants tested in this study, none were found to be superior to bovine serum.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Chen, Gaoqiang; Feng, Zhili; Zhu, Yucan
For better application of numerical simulation in optimization and design of friction stir welding (FSW), this paper presents a new frictional boundary condition at the tool/workpiece interface for computational fluid dynamics (CFD) modeling of FSW. The proposed boundary condition is based on an implementation of the Coulomb friction model. Using the new boundary condition, the CFD simulation yields non-uniform distribution of contact state over the tool/workpiece interface, as validated by the experimental weld macrostructure. It is found that interfacial sticking state is present over large area at the tool-workpiece interface, while significant interfacial sliding occurs at the shoulder periphery, themore » lower part of pin side, and the periphery of pin bottom. Due to the interfacial sticking, a rotating flow zone is found under the shoulder, in which fast circular motion occurs. The diameter of the rotating flow zone is smaller than the shoulder diameter, which is attributed to the presence of the interfacial sliding at the shoulder periphery. For the simulated welding condition, the heat generation due to friction and plastic deformation makes up 54.4 and 45.6% of the total heat generation rate, respectively. In conclusion, the simulated temperature field is validated by the good agreement to the experimental measurements.« less
Micro-miniature gas chromatograph column disposed in silicon wafers
Yu, Conrad M.
2000-01-01
A micro-miniature gas chromatograph column is fabricated by forming matching halves of a circular cross-section spiral microcapillary in two silicon wafers and then bonding the two wafers together using visual or physical alignment methods. Heating wires are deposited on the outside surfaces of each wafer in a spiral or serpentine pattern large enough in area to cover the whole microcapillary area inside the joined wafers. The visual alignment method includes etching through an alignment window in one wafer and a precision-matching alignment target in the other wafer. The two wafers are then bonded together using the window and target. The physical alignment methods include etching through vertical alignment holes in both wafers and then using pins or posts through corresponding vertical alignment holes to force precision alignment during bonding. The pins or posts may be withdrawn after curing of the bond. Once the wafers are bonded together, a solid phase of very pure silicone is injected in a solution of very pure chloroform into one end of the microcapillary. The chloroform lowers the viscosity of the silicone enough that a high pressure hypodermic needle with a thumbscrew plunger can force the solution into the whole length of the spiral microcapillary. The chloroform is then evaporated out slowly to leave the silicone behind in a deposit.
Chen, Gaoqiang; Feng, Zhili; Zhu, Yucan; ...
2016-07-11
For better application of numerical simulation in optimization and design of friction stir welding (FSW), this paper presents a new frictional boundary condition at the tool/workpiece interface for computational fluid dynamics (CFD) modeling of FSW. The proposed boundary condition is based on an implementation of the Coulomb friction model. Using the new boundary condition, the CFD simulation yields non-uniform distribution of contact state over the tool/workpiece interface, as validated by the experimental weld macrostructure. It is found that interfacial sticking state is present over large area at the tool-workpiece interface, while significant interfacial sliding occurs at the shoulder periphery, themore » lower part of pin side, and the periphery of pin bottom. Due to the interfacial sticking, a rotating flow zone is found under the shoulder, in which fast circular motion occurs. The diameter of the rotating flow zone is smaller than the shoulder diameter, which is attributed to the presence of the interfacial sliding at the shoulder periphery. For the simulated welding condition, the heat generation due to friction and plastic deformation makes up 54.4 and 45.6% of the total heat generation rate, respectively. In conclusion, the simulated temperature field is validated by the good agreement to the experimental measurements.« less
NASA Astrophysics Data System (ADS)
Nugroho, Tito Dwi; Purwadi, P. K.
2017-01-01
The function of the fin is to extend surfaces so that objects fitted with fin can remove the heat to the surrounding environment so that the cooling process can take place more quickly. The purpose of this study is to calculate and determine the effect of (a) the convective heat transfer coefficient of fluid on the value of the fin on the efficiency and effectiveness of non-steady state, and (b) the fin material to the value of the fins on the efficiency and effectiveness of non-steady state. The studied fins are in the form of straight fins with rhombus sectional area which is a function of position x with the short diagonal length of D1 and D2 as long diagonal length, L as fin's length and α as fin's tilt angle. Research solved numerical computation, using a finite difference method on the explicit way. At first, the fin has the same initial temperature with essentially temperature Ti = Tb, then abruptly fin conditioned on fluid temperature environment T∞. Fin's material is assumed with uniform properties, does not change with changes in temperature, and fin does not change the shape and volume during the process. The temperature of the fluid around the fins and the value of the convective heat transfer coefficient are permanently constant, and there is no energy generation in the fin. Fin's heat transfer conduction only take place in one direction, namely in the direction perpendicular to the fin base (or x-direction). The entire surface of the fin makes the process of heat transfer to a fluid environment around the fins. The results show that (a) the greater the value of heat transfer coefficient of convection h, the smaller the efficiency fin and effectiveness fins (b) In circumstances of unsteady state, the efficiency and effectivity influenced by the value of density, specific heat, heat transfer coefficient of conduction and thermal diffusivity fin material.
Rotor blades for turbine engines
Piersall, Matthew R; Potter, Brian D
2013-02-12
A tip shroud that includes a plurality of damping fins, each damping fin including a substantially non-radially-aligned surface that is configured to make contact with a tip shroud of a neighboring rotor blade. At least one damping fin may include a leading edge damping fin and at least one damping fin may include a trailing edge damping fin. The leading edge damping fin may be configured to correspond to the trailing edge damping fin.
NASA Technical Reports Server (NTRS)
Elovic, E. (Editor); O'Brien, J. E. (Editor); Pepper, D. W. (Editor)
1988-01-01
The present conference on heat transfer characteristics of gas turbines and three-dimensional flows discusses velocity-temperature fluctuation correlations at the flow stagnation flow of a circular cylinder in turbulent flow, heat transfer across turbulent boundary layers with pressure gradients, the effect of jet grid turbulence on boundary layer heat transfer, and heat transfer characteristics predictions for discrete-hole film cooling. Also discussed are local heat transfer in internally cooled turbine airfoil leading edges, secondary flows in vane cascades and curved ducts, three-dimensional numerical modeling in gas turbine coal combustor design, numerical and experimental results for tube-fin heat exchanger airflow and heating characteristics, and the computation of external hypersonic three-dimensional flow field and heat transfer characteristics.
NASA Astrophysics Data System (ADS)
Elovic, E.; O'Brien, J. E.; Pepper, D. W.
The present conference on heat transfer characteristics of gas turbines and three-dimensional flows discusses velocity-temperature fluctuation correlations at the flow stagnation flow of a circular cylinder in turbulent flow, heat transfer across turbulent boundary layers with pressure gradients, the effect of jet grid turbulence on boundary layer heat transfer, and heat transfer characteristics predictions for discrete-hole film cooling. Also discussed are local heat transfer in internally cooled turbine airfoil leading edges, secondary flows in vane cascades and curved ducts, three-dimensional numerical modeling in gas turbine coal combustor design, numerical and experimental results for tube-fin heat exchanger airflow and heating characteristics, and the computation of external hypersonic three-dimensional flow field and heat transfer characteristics.
50 CFR 600.1204 - Shark finning; possession at sea and landing of shark fins.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 50 Wildlife and Fisheries 12 2013-10-01 2013-10-01 false Shark finning; possession at sea and landing of shark fins. 600.1204 Section 600.1204 Wildlife and Fisheries FISHERY CONSERVATION AND... PROVISIONS Shark Finning § 600.1204 Shark finning; possession at sea and landing of shark fins. (a)(1) No...
50 CFR 600.1204 - Shark finning; possession at sea and landing of shark fins.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 50 Wildlife and Fisheries 10 2011-10-01 2011-10-01 false Shark finning; possession at sea and landing of shark fins. 600.1204 Section 600.1204 Wildlife and Fisheries FISHERY CONSERVATION AND... PROVISIONS Shark Finning § 600.1204 Shark finning; possession at sea and landing of shark fins. (a)(1) No...
50 CFR 600.1204 - Shark finning; possession at sea and landing of shark fins.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 50 Wildlife and Fisheries 12 2012-10-01 2012-10-01 false Shark finning; possession at sea and landing of shark fins. 600.1204 Section 600.1204 Wildlife and Fisheries FISHERY CONSERVATION AND... PROVISIONS Shark Finning § 600.1204 Shark finning; possession at sea and landing of shark fins. (a)(1) No...
50 CFR 600.1204 - Shark finning; possession at sea and landing of shark fins.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 50 Wildlife and Fisheries 12 2014-10-01 2014-10-01 false Shark finning; possession at sea and landing of shark fins. 600.1204 Section 600.1204 Wildlife and Fisheries FISHERY CONSERVATION AND... PROVISIONS Shark Finning § 600.1204 Shark finning; possession at sea and landing of shark fins. (a)(1) No...
Kinematics of ribbon-fin locomotion in the bowfin, Amia calva.
Jagnandan, Kevin; Sanford, Christopher P
2013-12-01
An elongated dorsal and/or anal ribbon-fin to produce forward and backward propulsion has independently evolved in several groups of fishes. In these fishes, fin ray movements along the fin generate a series of waves that drive propulsion. There are no published data on the use of the dorsal ribbon-fin in the basal freshwater bowfin, Amia calva. In this study, frequency, amplitude, wavelength, and wave speed along the fin were measured in Amia swimming at different speeds (up to 1.0 body length/sec) to understand how the ribbon-fin generates propulsion. These wave properties were analyzed to (1) determine whether regional specialization occurs along the ribbon-fin, and (2) to reveal how the undulatory waves are used to control swimming speed. Wave properties were also compared between swimming with sole use of the ribbon-fin, and swimming with simultaneous use of the ribbon and pectoral fins. Statistical analysis of ribbon-fin kinematics revealed no differences in kinematic patterns along the ribbon-fin, and that forward propulsive speed in Amia is controlled by the frequency of the wave in the ribbon-fin, irrespective of the contribution of the pectoral fin. This study is the first kinematic analysis of the ribbon-fin in a basal fish and the model species for Amiiform locomotion, providing a basis for understanding ribbon-fin locomotion among a broad range of teleosts. © 2013 Wiley Periodicals, Inc.
Role of Pectoral Fin Flexibility in Robotic Fish Performance
NASA Astrophysics Data System (ADS)
Bazaz Behbahani, Sanaz; Tan, Xiaobo
2017-08-01
Pectoral fins play a vital role in the maneuvering and locomotion of fish, and they have become an important actuation mechanism for robotic fish. In this paper, we explore the effect of flexibility of robotic fish pectoral fins on the robot locomotion performance and mechanical efficiency. A dynamic model for the robotic fish is presented, where the flexible fin is modeled as multiple rigid elements connected via torsional springs and dampers. Blade element theory is used to capture the hydrodynamic force on the fin. The model is validated with experimental results obtained on a robotic fish prototype, equipped with 3D-printed fins of different flexibility. The model is then used to analyze the impacts of fin flexibility and power/recovery stroke speed ratio on the robot swimming speed and mechanical efficiency. It is found that, in general, flexible fins demonstrate advantages over rigid fins in speed and efficiency at relatively low fin-beat frequencies, while rigid fins outperform flexible fins at higher frequencies. For a given fin flexibility, the optimal frequency for speed performance differs from the optimal frequency for mechanical efficiency. In addition, for any given fin, there is an optimal power/recovery stroke speed ratio, typically in the range of 2-3, that maximizes the speed performance. Overall, the presented model offers a promising tool for fin flexibility and gait design, to achieve speed and efficiency objectives for robotic fish actuated with pectoral fins.
How fish swim: flexible fin thrusters as an EAP platform
NASA Astrophysics Data System (ADS)
Lauder, George V.
2007-04-01
Fish are capable of remarkable locomotor performance and use their fins extensively for both propulsion and maneuvering. Recent interest in using fishes as inspiration for the design of a new generation of autonomous underwater vehicles has prompted both new experimental studies of fish locomotor function and efforts to use electroactive polymers (EAP) as actuators in fish-inspired propulsive devices. The fins of fishes allow precise control over body position and vectoring of thrust during propulsion and maneuvering. Recent experimental studies of fish locomotion have revealed that fins exhibit much greater flexibility than previously suspected and that there is considerable deformation of the fin surface during locomotion. The fins of the large group known as ray-finned fishes are supported by fin rays, which have a bilaminar structure that allows active curvature control of the ray and fin surface by the fin musculature. Fish have up to seven different fins, and these fins may interact with each other hydrodynamically during locomotion. Fish fins provide an excellent test platform for the use of electroactive polymer actuators as the frequency of movement is typically less than 5 Hz, and fin muscle strains typically range from 2 to 10%. Recent developments of biorobotic fish pectoral fins actuated with EAP are reviewed.
Richter, Philipp
2017-01-01
Abstract The median fins in extant actinopterygians are the product of millions of years of evolution. During this time, different developmental patterns for the dorsal and anal fins emerged leading to a high variation in median fin morphology and ontogeny. In this study, the development of anal and dorsal fins in atheriniforms is described and its consequences for the current phylogenetic hypothesis are discussed. Developmental series of five atheriniform species were investigated using clearing and staining as well as antibody staining. The skeletal elements of the second dorsal fin and the anal fin emerge in a bidirectional pattern. The first dorsal fin, however, arises separately in front of the second dorsal fin after this one is almost completely formed. The pterygiophores of the first dorsal fin, including the interdorsal pterygiophores, develop from caudal to rostral, but the fin‐spines of the first dorsal fin form in the opposite direction. This new mode of fin development has been found in all examined atheriniform species with two dorsal fins. Several morphological characters of atheriniforms, including interdorsal pterygiophores, are also found in one other taxon: the Mugiliformes. Thus, several dorsal fin characteristics may provide evidence for a closer relationship of these two taxa. PMID:28370120
Effect of Fin Passage Length on Optimization of Cylinder Head Cooling Fins
NASA Technical Reports Server (NTRS)
Siegel, R.; Graham, R. W.
1977-01-01
The heat transfer performance of baffled cooling fins on cylinder heads of small, air-cooled, general-aviation aircraft engines was analyzed to determine the potential for improving cooling fin design. Flow baffles were assumed to be installed tightly against the fin end edges, an ideal baffle configuration for guiding all flow between the fins. A rectangular flow passage is thereby formed between each set of two adjacent fins, the fin base surface, and the baffle. These passages extend around each side of the cylinder head, and the cooling air absorbs heat as it flows within them. For each flow passage length, the analysis was concerned with optimizing fin spacing and thickness to achieve the best heat transfer for each fin width. Previous literature has been concerned mainly with maximizing the local fin conductance and has not considered the heating of the gas in the flow direction, which leads to higher wall temperatures at the fin passage exits. If the fins are close together, there is a large surface area, but the airflow is restricted.
Tangorra, James L; Lauder, George V; Hunter, Ian W; Mittal, Rajat; Madden, Peter G A; Bozkurttas, Meliha
2010-12-01
A biorobotic pectoral fin was developed and used to study how the flexural rigidities of fin rays within a highly deformable fish fin affect the fin's propulsive forces. The design of the biorobotic fin was based on a detailed analysis of the pectoral fin of the bluegill sunfish (Lepomis macrochirus). The biorobotic fin was made to execute the kinematics used by the biological fin during steady swimming, and to have structural properties that modeled those of the biological fin. This resulted in an engineered fin that had a similar interaction with the water as the biological fin and that created close approximations of the three-dimensional motions, flows, and forces produced by the sunfish during low speed, steady swimming. Experimental trials were conducted during which biorobotic fins of seven different stiffness configurations were flapped at frequencies from 0.5 to 2.0 Hz in flows with velocities that ranged from 0 to 270 mm s(-1). During these trials, thrust and lift forces were measured, kinematics were recorded in three dimensions, and digital particle image velocimetry was used to evaluate flow hydrodynamics. The results of the trials revealed that slight changes to the fin's mechanical properties or to the operating conditions can have significant impact on the direction, magnitude and time course of the propulsive forces. In general, the magnitude of the 2-D (thrust and lift) propulsive force scaled with fin ray stiffness, and increased as the fin's flapping speed increased or as the velocity of the flow decreased.
NASA Technical Reports Server (NTRS)
Jorgensen, L. H.; Nelson, E. R.
1976-01-01
An experimental investigation was conducted by wind tunnel to measure the static aerodynamic characteristics for bodies of circular and elliptic cross section with various thin flat plate wings and a thin tail consisting of horizontal and vertical parts. The wings had aspect ratios of 4 and taper ratios of about 0, 0.25, and 0.5. Two additional wings, which had taper ratios near 0.25 and aspect ratios of about 3 and 5, were also tested in combination with the bodies and tail. All wings had about the same planform area. The exposed area of the horizontal portion of the tail was about 33 to 36 percent of the exposed area of the wings. The exposed area of the vertical tail fin was about 22 to 24 percent of the exposed area of the wings. The elliptic body, with an a/b = 2 cross section, had the same length and axial distribution of cross sectional area as the circular body. The circular body had a cylindrical aftersection of fineness ratio 7, and it was tested with the wings and tail in combination with tangent ogive noses that had fineness ratios of 2.5, 3.0, 3.5, and 5.0. In addition, an ogive nose with a rounded tip and an ogive nose with two different nose strake arrangements were used. Nineteen configuration combinations were tested at Mach numbers of 0.6, 0.9, 1.5, and 2.0 at angles of attack from 0 to 58 deg. The Reynolds numbers, based on body base diameter, were about 4.3 X 100,000.
Mapping interactions between the RNA chaperone FinO and its RNA targets
Arthur, David C.; Tsutakawa, Susan; Tainer, John A.; Frost, Laura S.; Glover, J. N. Mark
2011-01-01
Bacterial conjugation is regulated by two-component repression comprising the antisense RNA FinP, and its protein co-factor FinO. FinO mediates base-pairing of FinP to the 5′-untranslated region (UTR) of traJ mRNA, which leads to translational inhibition of the transcriptional activator TraJ and subsequent down regulation of conjugation genes. Yet, little is known about how FinO binds to its RNA targets or how this interaction facilitates FinP and traJ mRNA pairing. Here, we use solution methods to determine how FinO binds specifically to its minimal high affinity target, FinP stem–loop II (SLII), and its complement SLIIc from traJ mRNA. Ribonuclease footprinting reveals that FinO contacts the base of the stem and the 3′ single-stranded tails of these RNAs. The phosphorylation or oxidation of the 3′-nucleotide blocks FinO binding, suggesting FinO binds the 3′-hydroxyl of its RNA targets. The collective results allow the generation of an energy-minimized model of the FinO–SLII complex, consistent with small-angle X-ray scattering data. The repression complex model was constrained using previously reported cross-linking data and newly developed footprinting results. Together, these data lead us to propose a model of how FinO mediates FinP/traJ mRNA pairing to down regulate bacterial conjugation. PMID:21278162
Aiello, Brett R; Hardy, Adam R; Cherian, Chery; Olsen, Aaron M; Orsbon, Courtney P; Hale, Melina E; Westneat, Mark W
2018-04-25
The organization of tissues in appendages often affects their mechanical properties and function. In the fish family Labridae, swimming behavior is associated with pectoral fin flexural stiffness and morphology, where fins range on a continuum from stiff to relatively flexible fins. Across this diversity, pectoral fin flexural stiffness decreases exponentially along the length of any given fin ray, and ray stiffness decreases along the chord of the fin from the leading to trailing edge. In this study, we examine the morphological properties of fin rays, including the effective modulus in bending (E), second moment of area (I), segmentation, and branching patterns, and their impact on fin ray stiffness. We quantify intrinsic pectoral fin ray stiffness in similarly sized fins of two closely related species that employ fins of divergent mechanics, the flapping Gomphosus varius and the rowing Halichoeres bivittatus. While segmentation patterns and E were similar between species, measurements of I and the number of fin ray branch nodes were greater in G. varius than in H. bivittatus. A multiple regression model found that of these variables, I was always significantly correlated with fin ray flexural stiffness and that variation in I always explained the majority of the variation in flexural stiffness. Thus, while most of the morphological variables quantified in this study correlate with fin ray flexural stiffness, second moment of area is the greatest factor contributing to variation in flexural stiffness. Further, interspecific variation in fin ray branching pattern could be used as a means of tuning the effective stiffness of the fin webbing to differences in swimming behavior and hydrodynamics. The comparison of these results to other systems begins to unveil fundamental morphological features of biological beams and yields insight into the role of mechanical properties in fin deformation for aquatic locomotion. © 2018 Wiley Periodicals, Inc.
Hydrodynamic function of dorsal fins in spiny dogfish and bamboo sharks during steady swimming.
Maia, Anabela; Lauder, George V; Wilga, Cheryl D
2017-11-01
A key feature of fish functional design is the presence of multiple fins that allow thrust vectoring and redirection of fluid momentum to contribute to both steady swimming and maneuvering. A number of previous studies have analyzed the function of dorsal fins in teleost fishes in this context, but the hydrodynamic function of dorsal fins in freely swimming sharks has not been analyzed, despite the potential for differential functional roles between the anterior and posterior dorsal fins. Previous anatomical research has suggested a primarily stabilizing role for shark dorsal fins. We evaluated the generality of this hypothesis by using time-resolved particle image velocimetry to record water flow patterns in the wake of both the anterior and posterior dorsal fins in two species of freely swimming sharks: bamboo sharks ( Chiloscyllium plagiosum ) and spiny dogfish ( Squalus acanthias ). Cross-correlation analysis of consecutive images was used to calculate stroke-averaged mean longitudinal and lateral velocity components, and vorticity. In spiny dogfish, we observed a velocity deficit in the wake of the first dorsal fin and flow acceleration behind the second dorsal fin, indicating that the first dorsal fin experiences net drag while the second dorsal fin can aid in propulsion. In contrast, the wake of both dorsal fins in bamboo sharks displayed increased net flow velocity in the majority of trials, reflecting a thrust contribution to steady swimming. In bamboo sharks, fluid flow in the wake of the second dorsal fin had higher absolute average velocity than that for first dorsal fin, and this may result from a positive vortex interaction between the first and second dorsal fins. These data suggest that the first dorsal fin in spiny dogfish has primarily a stabilizing function, while the second dorsal fin has a propulsive function. In bamboo sharks, both dorsal fins can contribute thrust and should be considered as propulsive adjuncts to the body during steady swimming. The function of shark dorsal fins can thus differ considerably among fins and species, and is not limited to a stabilizing role. © 2017. Published by The Company of Biologists Ltd.
Flammang, Brooke E; Lauder, George V
2016-10-01
Most teleost fishes, like the bluegill sunfish Lepomis macrochirus, have multiple flexible fins that are used as modifiable control surfaces. This helps to make fish highly maneuverable, permitting behaviors like reversing direction of motion and swimming backwards without having to rotate body position. To answer the question of how fish swim backwards we used high-speed videography and electromyography to determine the kinematics and muscle activity necessary to produce reverse-direction propulsion in four bluegill sunfish. We found that, in contrast to slow forward swimming, low-speed backward swimming is a multi-fin behavior, utilizing the pectoral, dorsal, anal, and caudal fins. The pectoral fins alternate beats, each fin broadly flaring on the outstroke and feathered on the instroke. The dorsal fin and dorsal portion of the caudal fin move out of phase as do the anal fin and ventral portion of the caudal fin. Electromyography of muscles in the pectoral, dorsal, anal, and caudal fins demonstrated bilateral activation when these fins changed direction, suggesting that fins are stiffened at this time. In addition to backward propulsion by the pectoral fins, particle image velocimetry revealed that the dorsal and anal fins are capable of producing reverse momentum jets to propel the fish backward. Because teleost fishes are statically unstable, locomotion at slow speeds requires precise fin control to adequately balance torques produced about the center of mass. Therefore, the kinematics of backward swimming may be the result of compensation for rolling, pitching, and yawning instability. We suggest that asymmetric pectoral fin activity with feathering during adduction balances rolling instability. The ventral to dorsal undulatory wave on the caudal fin controls pitch instability and yaw instability encountered from pectoral-driven backward locomotion. Thrust generation from the dorsal and anal fins decreases the destabilizing effect of the long moment arm of the tail in backward swimming. Thus, backward locomotion at slow speed is not simply the reverse of slow forward swimming. Copyright © 2016 Elsevier GmbH. All rights reserved.
NASA Astrophysics Data System (ADS)
Moorthy, P.; Oumer, A. N.; Ishak, M.
2018-03-01
The aim of this paper is to investigate the effect of fin shapes on the performance of compact finned flat tube heat exchangers. Three types of fin shapes namely plain, wavy, and rectangular grooved fins attached to three by three arrays of flat tube banks were considered. Moreover, the tubes were deployed in in-line and staggered arrangements. In addition to the fin shapes, the air velocity and the tube inclination angles were varied and the thermal-hydraulic performance was analysed. On the other hand, the temperatures at the tube surfaces were kept constant to produce constant heat flux throughout the study. The results showed that as flowrate increases, the heat transfer increases, however, the friction factor decreases. Staggered arrangement produces higher heat transfer and friction factor than inline fin. Moreover, the rectangular fin is the best in terms of high heat transfer however the drawback of high friction factor leads the fin to have the least efficiency of all. On the other hand, plain fin had the least heat transfer performance however the highest efficiency was achieved. Therefore, plain fin should be used when efficiency is prioritized and rectangular fin when high heat transfer is desired.
Facaros, Zacharia; Ramanujam, Crystal L.; Stapleton, John J.
2010-01-01
The surgical management of ankle fractures among the diabetic population is associated with higher complication rates compared to the general population. Efforts toward development of better methods in prevention and treatment are continuously evolving for these injuries. The presence of peripheral neuropathy and the possible development of Charcot neuroarthropathy in this high risk patient population have stimulated much surgical interest to create more stable osseous constructs when open reduction of an ankle fracture/dislocation is required. The utilization of multiple syndesmotic screws (pro-syndesmotic screws) to further stabilize the ankle mortise has been reported by many foot and ankle surgeons. In addition, transarticular Steinmann pins have been described as an adjunct to traditional open reduction with internal fixation (ORIF) of the ankle to better stabilize the talus, thus minimizing risk of further displacement, malunion, and Charcot neuroarthropathy. The authors present a unique technique of ORIF with pro-syndesmotic screws and the application of a multi-plane circular external fixator for management of a neglected diabetic ankle fracture that prevented further deformity while allowing a weight-bearing status. This techniqu may be utilized for the management of complex diabetic ankle fractures that are prone to future complications and possible limb loss. PMID:22396812
Impact of line edge roughness on the performance of 14-nm FinFET: Device-circuit Co-design
NASA Astrophysics Data System (ADS)
Rathore, Rituraj Singh; Rana, Ashwani K.
2018-01-01
With the evolution of sub-20 nm FinFET technology, line edge roughness (LER) has been identified as a critical problem and may result in critical device parameter variation and performance limitation in the future VLSI circuit application. In the present work, an analytical model of fin-LER has been presented, which shows the impact of correlated and uncorrelated LER on FinFET structure. Further, the influence of correlated and uncorrelated fin- LER on all electrical performance parameters is thoroughly investigated using the three-dimensional (3-D) Technology Computer Aided Design (TCAD) simulations for 14-nm technology node. Moreover, the impact of all possible fin shapes on threshold voltage (VTH), drain induced barrier lowering (DIBL), on-current (ION), and off-current (IOFF) has been compared with the well calibrated rectangular FinFET structure. In addition, the influence of all possible fin geometries on the read stability of six-transistor (6-T) Static-Random-Access-Memory (SRAM) has been investigated. The study reveals that fin-LER plays a vital role as it directly governs the electrostatics of the FinFET structure. This has been found that there is a high degree of fluctuations in all performance parameters for uncorrelated fin-LER type FinFETs as compared to correlated fin-LER with respect to rectangular FinFET structure. This paper gives physical insight of FinFET design, especially in sub-20 nm technology nodes by concluding that the impact of LER on electrical parameters are minimum for correlated LER.
NASA Astrophysics Data System (ADS)
Khalkhali, Abolfazl; Ebrahimi-Nejad, Salman; Geran Malek, Nima
2018-06-01
Friction stir welding (FSW) process overcomes many difficulties arising in conventional fusion welding processes of aluminum alloys. The current paper presents a comprehensive investigation on the effects of rotational speed, traverse speed, tool tilt angle and tool pin profile on the longitudinal force, axial force, maximum temperature, tensile strength, percent elongation, grain size, micro-hardness of welded zone and welded zone thickness of AA1100 aluminum alloy sheets. Design of experiments (DOE) was applied using the Taguchi approach and subsequently, effects of the input parameter on process outputs were investigated using analysis of variance (ANOVA). A perceptron neural network model was developed to find a correlation between the inputs and outputs. Multi-objective optimization using modified NSGA-II was implemented followed by NIP and TOPSIS approaches to propose optimum points for each of the square, pentagon, hexagon, and circular pin profiles. Results indicate that the optimization process can reach horizontal and vertical forces as low as 1452 N and 2913 N, respectively and a grain size as low as 2 μm. This results in hardness values of up to 57.2 and tensile strength, elongation and joint thickness of 2126 N, 5.9% and 3.7 mm, respectively. The maximum operating temperature can also reach a sufficiently high value of 374 °C to provide adequate material flow.
Treatment of unstable distal radius fractures with Ilizarov circular, nonbridging external fixator.
Tyllianakis, Minos; Mylonas, Spyros; Saridis, Alkis; Kallivokas, Alkiviadis; Kouzelis, Antonis; Megas, Panagiotis
2010-03-01
Unstable distal radius fractures remain a challenge for the treating orthopaedic surgeon. We present a retrospective follow-up study (mean follow-up 12.5 months) of 20 patients with 21 unstable distal radius fractures that were reduced in a closed manner and stabilized with a nonbridging Ilizarov external fixator. Subsequent insertion of olive wires for interfragmentary compression was performed in cases with intra-articular fractures. According to the overall evaluation proposed by Gartland and Werley scoring system 12 wrists were classified as excellent, 6 as good, 2 as fair and 1 as poor. Grade II pin-tract infection in distal fracture fragment was detected in 3 wires from a total of 78 (3.8%) and in 4 half pins out of a total of 9 (44.4%). Pronation was the most frequently impaired movement. This was restricted in 4 patients (19%) in whom a radioulnar transfixing wire was applied. Symptoms of irritation of superficial sensory branch of the radial nerve occurred in 3 patients with an olive wire applied in a closed manner in the distal fragment. Ilizarov method yields functional results comparable to that of other methods whilst it avoids wrist immobilization, open reduction and reoperation for implant removal. The method is associated with a low rate of major complication and satisfactory functional outcome. Copyright 2009 Elsevier Ltd. All rights reserved.
50 CFR 600.1204 - Shark finning; possession at sea and landing of shark fins.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 50 Wildlife and Fisheries 8 2010-10-01 2010-10-01 false Shark finning; possession at sea and... PROVISIONS Shark Finning § 600.1204 Shark finning; possession at sea and landing of shark fins. (a)(1) No...)(2), except that sharks may be dressed at sea. (c) No person aboard a U.S. or foreign fishing vessel...
Actuation of a robotic fish caudal fin for low reaction torque
NASA Astrophysics Data System (ADS)
Yun, Dongwon; Kim, Kyung-Soo; Kim, Soohyun; Kyung, Jinho; Lee, Sunghee
2011-07-01
In this paper, a novel caudal fin for actuating a robotic fish is presented. The proposed caudal fin waves in a vertical direction with a specific spatial shape, which is determined by a so-called shape factor. For a specific shape factor, a traveling wave with a vertical phase difference is formed on a caudal fin during fin motion. It will be shown by the analysis that the maximum reaction torque at the joint of a caudal fin varies depending on the shape factors. Compared with a conventional plate type caudal fin, the proposed fin with a shape factor of 2π can eliminate the reaction torque perfectly, while keeping the propulsion force unchanged. The benefits of the proposed fin will be demonstrated by experiments.
Driving mechanism of unsteady separation shock motion in hypersonic interactive flow
NASA Technical Reports Server (NTRS)
Dolling, D. S.; Narlo, J. C., II
1987-01-01
Wall pressure fluctuations were measured under the steady separation shock waves in Mach 5 turbulent interactions induced by unswept circular cylinders on a flat plate. The wall temperature was adiabatic. A conditional sampling algorithm was developed to examine the statistics of the shock wave motion. The same algorithm was used to examine data taken in earlier studies in the Princeton University Mach 3 blowdown tunnel. In these earlier studies, hemicylindrically blunted fins of different leading-edge diameters were tested in boundary layers which developed on the tunnel floor and on a flat plate. A description of the algorithm, the reasons why it was developed and the sensitivity of the results to the threshold settings, are discussed. The results from the algorithm, together with cross correlations and power spectral density estimates suggests that the shock motion is driven by the low-frequency unsteadiness of the downstream separated, vortical flow.
Chimera grids in the simulation of three-dimensional flowfields in turbine-blade-coolant passages
NASA Technical Reports Server (NTRS)
Stephens, M. A.; Rimlinger, M. J.; Shih, T. I.-P.; Civinskas, K. C.
1993-01-01
When computing flows inside geometrically complex turbine-blade coolant passages, the structure of the grid system used can affect significantly the overall time and cost required to obtain solutions. This paper addresses this issue while evaluating and developing computational tools for the design and analysis of coolant-passages, and is divided into two parts. In the first part, the various types of structured and unstructured grids are compared in relation to their ability to provide solutions in a timely and cost-effective manner. This comparison shows that the overlapping structured grids, known as Chimera grids, can rival and in some instances exceed the cost-effectiveness of unstructured grids in terms of both the man hours needed to generate grids and the amount of computer memory and CPU time needed to obtain solutions. In the second part, a computational tool utilizing Chimera grids was used to compute the flow and heat transfer in two different turbine-blade coolant passages that contain baffles and numerous pin fins. These computations showed the versatility and flexibility offered by Chimera grids.
Quantification of local strain distributions in nanoscale strained SiGe FinFET structures
NASA Astrophysics Data System (ADS)
Mochizuki, Shogo; Murray, Conal E.; Madan, Anita; Pinto, Teresa; Wang, Yun-Yu; Li, Juntao; Weng, Weihao; Jagannathan, Hemanth; Imai, Yasuhiko; Kimura, Shigeru; Takeuchi, Shotaro; Sakai, Akira
2017-10-01
Strain within nanoscale strained SiGe FinFET structures has been investigated using a combination of X-ray diffraction and transmission electron microscopy-based nanobeam diffraction (NBD) techniques to reveal the evolution of the stress state within the FinFETs. Reciprocal space maps collected using high-resolution X-ray diffraction exhibited distinct features corresponding to the SiGe fin width, pitch, and lattice deformation and were analyzed to quantify the state of stress within the fins. Although the majority of the SiGe fin volume exhibited a uniaxial stress state due to elastic relaxation of the transverse in-plane stress, NBD measurements confirmed a small interaction region near the SOI interface that is mechanically constrained by the underlying substrate. We have quantitatively characterized the evolution of the fin stress state from biaxial to uniaxial as a function of fin aspect ratio and Ge fraction and confirmed that the fins obey elastic deformation based on a model that depends on the relative difference between the equilibrium Si and SiGe lattice constants and relative fraction of in-plane stress transverse to the SiGe fins. Spatially resolved, nanobeam X-ray diffraction measurements conducted near the SiGe fin edge indicate the presence of additional elastic relaxation from a uniaxial stress state to a fully relaxed state at the fin edge. Mapping of the lattice deformation within 500 nm of this fin edge by NBD revealed large gradients, particularly at the top corner of the fin. The values of the volume averaged lattice deformation obtained by nanoXRD and NBD are qualitatively consistent. Furthermore, the modulation of strain at the fin edge obtained by quantitative analysis of the nanoXRD results agrees with the lattice deformation profile obtained by NBD.
Akimenko, M A; Johnson, S L; Westerfield, M; Ekker, M
1995-02-01
To study the genetic regulation of growth control and pattern formation during fin development and regeneration, we have analysed the expression of four homeobox genes, msxA, msxB, msxC and msxD in zebrafish fins. The median fin fold, which gives rise to the unpaired fins, expresses these four msx genes during development. Transcripts of the genes are also present in cells of the presumptive pectoral fin buds. The most distal cells, the apical ectodermal ridge of the paired fins and the cleft and flanking cells of the median fin fold express all these msx genes with the exception of msxC. Mesenchymal cells underlying the most distal cells express all four genes. Expression of the msx genes in the fin fold and fin buds is transient and, by 3 days after fertilization, msx expression in the median fin fold falls below levels detectable by in situ hybridization. Although the fins of adult zebrafish normally have levels of msx transcripts undetectable by in situ hybridization, expression of all four genes is strongly reinduced during regeneration of both paired and unpaired fins. Induction of msx gene expression in regenerating caudal fins occurs as early as 30 hours postamputation. As the blastema forms, the levels of expression increase and reach a maximum between the third and fifth days. Then, msx expression progressively declines and disappears by day 12 when the caudal fin has grown back to its normal size. In the regenerating fin, the blastema cells that develop at the tip of each fin ray express msxB and msxC. Cells of the overlying epithelium express msxA and msxD, but do not express msxB or msxC. Amputations at various levels along the proximodistal axis of the fin suggest that msxB expression depends upon the position of the blastema, with cells of the rapidly proliferating proximal blastema expressing higher levels than the cells of the less rapidly proliferating distal blastema. Expression of msxC and msxD is independent of the position of the blastema cell along this axis. Our results suggest distinct roles for each of the four msx genes during fin development and regeneration and differential regulation of their expression.
Integration of oceanographic data with fin whale calling presence in the Bering Sea
NASA Astrophysics Data System (ADS)
Dasarathy, S.; Berchok, C.; Stabeno, P. J.; Crance, J.
2016-02-01
Through the integration of environmental data with passive acoustic monitoring, it is possible to investigate whether fin whale (Balaenoptera physalus) presence is influenced by environmental factors. Fin whale calling activity and concurrent environmental variables were analyzed from May 2012 to September 2013. These data were collected from passive acoustic and oceanographic moorings located in the Bering Sea. Fin whale calling presence was strongly correlated with three of the eight parameters analyzed: ice concentration, chlorophyll (a proxy for primary production), and temperature. Fin whale calling was negatively correlated with ice concentration; as ice concentration increased, fin whale calling decreased. A strong positive correlation was observed between fin whale calling and chlorophyll. A large spike in chlorophyll concentration in July 2013 preceded fin whale calling at the northern location. Fin whale calling also increased concurrently with a mixing of the water column (evidenced in the temperature data) at a depth of 30 to 50m. Peaks in chlorophyll concentration occurred after the mixing of the water column, and followed an increase in fin whale calling. These data illustrate the relationship between fin whale presence and environmental variables in the Bering Sea. These correlations may be used to predict the impact of climate change on fin whale populations in the rapidly changing environment of the Bering Sea.
NASA Astrophysics Data System (ADS)
Farjam, Aslan; Cormier, Yannick; Dupuis, Philippe; Jodoin, Bertrand; Corbeil, Antoine
2015-10-01
In this work, aluminum and aluminum-alumina powder mixtures were used to produce pyramidal fin arrays on aluminum substrates using cold spray as an additive manufacturing process. Using aluminum-alumina mixtures instead of pure aluminum powder could be seen as a cost-effective measure, preventing nozzle clogging or the need to use expensive polymer nozzles that wear out rapidly during cold spray. The fin geometries that were produced were observed using a 3D digital microscope to determine the flow passages width and fins' geometric details. Heat transfer and pressure drop tests were carried out using different ranges of appropriate Reynolds numbers for the sought commercial application to compare each fin array and determine the effect of alumina content. It was found that the presence of alumina reduces the fins' performance when compared to pure aluminum fins but that they were still outperforming traditional fins. Numerical simulations were performed to model the fin arrays and were used to predict the pressure loss in the fin array and compare these results with experimental values. The numerical model opens up new avenues in predicting different applicable operating conditions and other possible fin shapes using the same fin composition, instead of performing costly and time-consuming experiments.
An Investigation at Low Speed of the Spin Instability of Mortar-Shell Tails
NASA Technical Reports Server (NTRS)
Bird, John D.; Lichtenstein, Jacob H.
1957-01-01
An investigation was made in the Langley stability tunnel to study the influence of number of fins, fin shrouding, and fin aspect ratio on the spin instability of mortar-shell tail surfaces. It was found that the 12-fin tails tested spun less rapidly throughout the angle-of-yaw range than did the 6-fin tails and that fin shrouding reduced the spin encountered by a large amount.
Fin degeneration of young-of-the-year Alosa pseudoharengus (Clupeidae) in southern Lake Michigan
Brown, Edward H.; Norden, Carroll R.
1970-01-01
Young-of-the-year alewives, Alosa pseudoharengus, with extremely shortened caudal fins were observed at four locations in southern Lake Michigan between 1964 and 1968. Some of the fins appeared stunted or underdeveloped, but microscopic examination revealed a deterioration of the fins and not an ontogenetic abnormality. Deterioration of the caudal fin was frequently accompanied by degeneration of the dorsal and anal fins. Degenerate fins were not found on other species nor on older alewives, with the exception of one known yearling alewife at Waukegan and possibly a few of the larger fish at Milwaukee.
Deslauriers, David; Johnston, Ryan; Chipps, Steven R.
2016-01-01
We assessed the effect of fin-curl on the swimming and station-holding ability of juvenile shovelnose sturgeon Scaphirhynchus platorynchus (mean fork length = 17 cm; mean weight = 16 g; n = 21) using a critical swimming speed test performed in a small swim chamber (90 L) at 20°C. We quantified fin-curl severity using the pectoral fin index. Results showed a positive relationship between pectoral fin index and critical swimming speed indicative of reduced swimming performance displayed by fish afflicted with a pectoral fin index < 8%. Fin-curl severity, however, did not affect the station-holding ability of individual fish. Rather, fish affected with severe fin-curl were likely unable to use their pectoral fins to position their body adequately in the water column, which led to the early onset of fatigue. Results generated from this study should serve as an important consideration for future stocking practices.
Highly flexible SRAM cells based on novel tri-independent-gate FinFET
NASA Astrophysics Data System (ADS)
Liu, Chengsheng; Zheng, Fanglin; Sun, Yabin; Li, Xiaojin; Shi, Yanling
2017-10-01
In this paper, a novel tri-independent-gate (TIG) FinFET is proposed for highly flexible SRAM cells design. To mitigate the read-write conflict, two kinds of SRAM cells based on TIG FinFETs are designed, and high tradeoff are obtained between read stability and speed. Both cells can offer multi read operations for frequency requirement with single voltage supply. In the first TIG FinFET SRAM cell, the strength of single-fin access transistor (TIG FinFET) can be flexibly adjusted by selecting five different modes to meet the needs of dynamic frequency design. Compared to the previous double-independent-gate (DIG) FinFET SRAM cell, 12.16% shorter read delay can be achieved with only 1.62% read stability decrement. As for the second TIG FinFET SRAM cell, pass-gate feedback technology is applied and double-fin TIG FinFETs are used as access transistors to solve the severe write-ability degradation. Three modes exist to flexibly adjust read speed and stability, and 68.2% larger write margin and 51.7% shorter write delay are achieved at only the expense of 26.2% increase in leakage power, with the same layout area as conventional FinFET SRAM cell.
Effect of Fin Porosity on Wake Geometry for Flapping Fins at Intermediate Reynolds Number
NASA Astrophysics Data System (ADS)
Chen, J.; Xia, B.; Krueger, P. S.
2017-11-01
Low aspect ratio flapping fins generate interesting 3-dimensional flow structures as has been observed, for example, in studies of fish swimming. As the Reynolds number is reduced, the exact geometry of the fin is less important and even certain amounts of porosity might be allowed without significantly affecting propulsive performance. These effects are investigated experimentally using flapping rectangular fins of aspect ratio 2 at Reynolds numbers in the range 100 - 1000. The experiments were conducted using a water tunnel to supply the free stream flow and the fin flapping parameters were set to provide a Strouhal number (based on amplitude of the fin tip motion) in the range 0.15 - 0.35. Phase-averaged measurements were made of the 3-dimensional, volumetric flow field, allowing visualization of the typical shed vortex structure behind the fin and calculation of time averaged thrust and propulsive efficiency. Results comparing the flow structure in the fin wake and the resulting propulsive performance will be presented for several fins with different planform porosities where the porosities are set using arrays of holes in the fins. This material is based on the work supported by the National Science Foundation under Grant No. 1510707.
Grid Fin Stabilization of the Orion Launch Abort Vehicle
NASA Technical Reports Server (NTRS)
Pruzan, Daniel A.; Mendenhall, Michael R.; Rose, William C.; Schuster, David M.
2011-01-01
Wind tunnel tests were conducted by Nielsen Engineering & Research (NEAR) and Rose Engineering & Research (REAR) in conjunction with the NASA Engineering & Safety Center (NESC) on a 6%-scale model of the Orion launch abort vehicle (LAV) configured with four grid fins mounted near the base of the vehicle. The objectives of these tests were to 1) quantify LAV stability augmentation provided by the grid fins from subsonic through supersonic Mach numbers, 2) assess the benefits of swept grid fins versus unswept grid fins on the LAV, 3) determine the effects of the LAV abort motors on grid fin aerodynamics, and 4) generate an aerodynamic database for use in the future application of grid fins to small length-to-diameter ratio vehicles similar to the LAV. The tests were conducted in NASA Ames Research Center's 11x11-foot transonic wind tunnel from Mach 0.5 through Mach 1.3 and in their 9x7-foot supersonic wind tunnel from Mach 1.6 through Mach 2.5. Force- and moment-coefficient data were collected for the complete vehicle and for each individual grid fin as a function of angle of attack and sideslip angle. Tests were conducted with both swept and unswept grid fins with the simulated abort motors (cold jets) off and on. The swept grid fins were designed with a 22.5deg aft sweep angle for both the frame and the internal lattice so that the frontal projection of the swept fins was the same as for the unswept fins. Data from these tests indicate that both unswept and swept grid fins provide significant improvements in pitch stability as compared to the baseline vehicle over the Mach number range investigated. The swept fins typically provide improved stability as compared to the unswept fins, but the performance gap diminished as Mach number was increased. The aerodynamic performance of the fins was not observed to degrade when the abort motors were turned on. Results from these tests indicate that grid fins can be a robust solution for stabilizing the Orion LAV over a wide range of operating conditions.
Passively cooled direct drive wind turbine
Costin, Daniel P [Chelsea, VT
2008-03-18
A wind turbine is provided that passively cools an electrical generator. The wind turbine includes a plurality of fins arranged peripherally around a generator house. Each of the fins being oriented at an angle greater than zero degrees to allow parallel flow of air over the fin. The fin is further tapered to allow a constant portion of the fin to extend beyond the air stream boundary layer. Turbulence initiators on the nose cone further enhance heat transfer at the fins.
Parametric Fin-Body and Fin-Plate Database for a Series of 12 Missile Fins
NASA Technical Reports Server (NTRS)
Allen, Jerry M.
2001-01-01
A cooperative experimental investigation has been performed to obtain a systematic fin-body and fin-plate database for a series of 12 missile fins. These data are intended to complement and extend the information contained in the Triservice missile project and to provide a systematic set of experimental data from which fin-body interference factors can be derived. Data were obtained with the fins mounted on both an axisymmetric body and on a flat plate that was used to simulate fin-alone measurements. The experiments were conducted at Mach numbers from 0.60 to 3.95; fin deflection angles of 0 deg, 10 deg, and -10 deg; and angles of attack up to 30 deg on the body and up to 95 deg on the flat plate. The data were obtained from three-component balances attached to the fins and a six-component balance located in the axisymmetric body. The data obtained in this project are documented in tabular form in this report. In addition, selected data are presented in graphical form to illustrate the effects of the test variables. These variables are configuration angle of attack; Mach number; and fin parameters of deflection angle, planform size, taper ratio, and aspect ratio. A very limited comparison with the Triservice missile data is made to illustrate the consistency between the data from these two projects.
Mechanosensation is evolutionarily tuned to locomotor mechanics
Aiello, Brett R.; Westneat, Mark W.; Hale, Melina E.
2017-01-01
The biomechanics of animal limbs has evolved to meet the functional demands for movement associated with different behaviors and environments. Effective movement relies not only on limb mechanics but also on appropriate mechanosensory feedback. By comparing sensory ability and mechanics within a phylogenetic framework, we show that peripheral mechanosensation has evolved with limb biomechanics, evolutionarily tuning the neuromechanical system to its functional demands. We examined sensory physiology and mechanics of the pectoral fins, forelimb homologs, in the fish family Labridae. Labrid fishes exhibit extraordinary morphological and behavioral diversity and use pectoral fin-based propulsion with fins ranging in shape from high aspect ratio (AR) wing-like fins to low AR paddle-like fins. Phylogenetic character analysis demonstrates that high AR fins evolved independently multiple times in this group. Four pairs of species were examined; each included a plesiomorphic low AR and a high AR species. Within each species pair, the high AR species demonstrated significantly stiffer fin rays in comparison with the low AR species. Afferent sensory nerve activity was recorded during fin ray bending. In all cases, afferents of stiffer fins were more sensitive at lower displacement amplitudes, demonstrating mechanosensory tuning to fin mechanics and a consistent pattern of correlated evolution. We suggest that these data provide a clear example of parallel evolution in a complex neuromechanical system, with a strong link between multiple phenotypic characters: pectoral fin shape, swimming behavior, fin ray stiffness, and mechanosensory sensitivity. PMID:28396411
14 CFR 23.445 - Outboard fins or winglets.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Outboard fins or winglets. 23.445 Section... § 23.445 Outboard fins or winglets. (a) If outboard fins or winglets are included on the horizontal... with loads induced by the fins or winglets and moments or forces exerted on the horizontal surfaces or...
14 CFR 23.445 - Outboard fins or winglets.
Code of Federal Regulations, 2011 CFR
2011-01-01
... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Outboard fins or winglets. 23.445 Section... § 23.445 Outboard fins or winglets. (a) If outboard fins or winglets are included on the horizontal... with loads induced by the fins or winglets and moments or forces exerted on the horizontal surfaces or...
14 CFR 23.445 - Outboard fins or winglets.
Code of Federal Regulations, 2013 CFR
2013-01-01
... 14 Aeronautics and Space 1 2013-01-01 2013-01-01 false Outboard fins or winglets. 23.445 Section... § 23.445 Outboard fins or winglets. (a) If outboard fins or winglets are included on the horizontal... with loads induced by the fins or winglets and moments or forces exerted on the horizontal surfaces or...
Patterning of leaf vein networks by convergent auxin transport pathways.
Sawchuk, Megan G; Edgar, Alexander; Scarpella, Enrico
2013-01-01
The formation of leaf vein patterns has fascinated biologists for centuries. Transport of the plant signal auxin has long been implicated in vein patterning, but molecular details have remained unclear. Varied evidence suggests a central role for the plasma-membrane (PM)-localized PIN-FORMED1 (PIN1) intercellular auxin transporter of Arabidopsis thaliana in auxin-transport-dependent vein patterning. However, in contrast to the severe vein-pattern defects induced by auxin transport inhibitors, pin1 mutant leaves have only mild vein-pattern defects. These defects have been interpreted as evidence of redundancy between PIN1 and the other four PM-localized PIN proteins in vein patterning, redundancy that underlies many developmental processes. By contrast, we show here that vein patterning in the Arabidopsis leaf is controlled by two distinct and convergent auxin-transport pathways: intercellular auxin transport mediated by PM-localized PIN1 and intracellular auxin transport mediated by the evolutionarily older, endoplasmic-reticulum-localized PIN6, PIN8, and PIN5. PIN6 and PIN8 are expressed, as PIN1 and PIN5, at sites of vein formation. pin6 synthetically enhances pin1 vein-pattern defects, and pin8 quantitatively enhances pin1pin6 vein-pattern defects. Function of PIN6 is necessary, redundantly with that of PIN8, and sufficient to control auxin response levels, PIN1 expression, and vein network formation; and the vein pattern defects induced by ectopic PIN6 expression are mimicked by ectopic PIN8 expression. Finally, vein patterning functions of PIN6 and PIN8 are antagonized by PIN5 function. Our data define a new level of control of vein patterning, one with repercussions on other patterning processes in the plant, and suggest a mechanism to select cell files specialized for vascular function that predates evolution of PM-localized PIN proteins.
NASA Astrophysics Data System (ADS)
Liu, Jing-cheng; Wei, Xiu-ting; Zhou, Zhi-yong; Wei, Zhen-wen
2018-03-01
The fluid-structure interaction performance of plate-fin heat exchanger (PFHE) with serrated fins in large scale air-separation equipment was investigated in this paper. The stress and deformation of fins were analyzed, besides, the interaction equations were deduced by Galerkin method. The governing equations of fluid flow and heat transfer in PFHE were deduced by finite volume method (FVM). The distribution of strain and stress were calculated in large scale air separation equipment and the coupling situation of serrated fins under laminar situation was analyzed. The results indicated that the interactions between fins and fluid flow in the exchanger have significant impacts on heat transfer enhancement, meanwhile, the strain and stress of fins includes dynamic pressure of the sealing head and flow impact with the increase of flow velocity. The impacts are especially significant at the conjunction of two fins because of the non-alignment fins. It can be concluded that the soldering process and channel width led to structure deformation of fins in the exchanger, and degraded heat transfer efficiency.
Investigation of thermal effects on FinFETs in the quasi-ballistic regime
NASA Astrophysics Data System (ADS)
Yin, Longxiang; Shen, Lei; Di, Shaoyan; Du, Gang; Liu, Xiaoyan
2018-04-01
In this work, the thermal effects of FinFETs in the quasi-ballistic regime are investigated using the Monte Carlo method. Bulk Si nFinFETs with the same fin structure and two different gate lengths L g = 20 and 80 nm are investigated and compared to evaluate the thermal effects on the performance of FinFETs in the quasi-ballistic regime. The on current of the 20 nm FinFET with V gs = 0.7 V does not decrease with increasing lattice temperature (T L) at a high V ds. The electrostatic properties in the 20 nm FinFET are more affected by T L than those in the 80 nm FinFET. However, the electron transport in the 20 nm FinFET is less affected by T L than that in the 80 nm FinFET. The electrostatic properties being more sensitive and the electron transport being less sensitive to thermal effects in the quasi-ballistic regime than in the diffusive regime should be considered for effective device modeling and design.
Forced air heat sink apparatus
NASA Technical Reports Server (NTRS)
Rippel, Wally E. (Inventor)
1989-01-01
A high efficiency forced air heat sink assembly employs a split feed transverse flow configuration to minimize the length of the air flow path through at least two separated fin structures. Different embodiments use different fin structure material configurations including honeycomb, corrugated and serpentine. Each such embodiment uses a thermally conductive plate having opposed exterior surfaces; one for receiving a component to be cooled and one for receiving the fin structures. The serpentine structured fin embodiment employs a plurality of fin supports extending from the plate and forming a plurality of channels for receiving the fin structures. A high thermal conductivity bondant, such as metal-filled epoxy, may be used to bond the fin structures to either the plate or the fin supports. Dip brazing and soldering may also be employed depending upon the materials selected.
2018-01-01
Plant development is affected by the integration of light and phytohormones, including jasmonates (JAs). To address the molecular mechanisms of possible interactions between blue light and JA signaling in Arabidopsis thaliana, we used molecular and transgenic approaches to understand the regulatory relationships between FAR-RED INSENSITIVE 219 (FIN219)/JASMONATE RESISTANT1 (JAR1) and the blue-light photoreceptor cryptochrome1 (CRY1). FIN219 overexpression in the wild type resulted in a short-hypocotyl phenotype under blue light. However, FIN219 overexpression in cry1, cry2 and cry1cry2 double mutant backgrounds resulted in phenotypes similar to their respective mutant backgrounds, which suggests that FIN219 function may require blue light photoreceptors. Intriguingly, FIN219 overexpression in transgenic plants harboring ectopic expression of the C terminus of CRY1 (GUS-CCT1), which exhibits a hypersensitive short-hypocotyl phenotype in all light conditions including darkness, led to a rescued phenotype under all light conditions except red light. Further expression studies showed mutual suppression between FIN219 and CRY1 under blue light. Strikingly, FIN219 overexpression in GUS-CCT1 transgenic lines (FIN219-OE/GUS-CCT1) abolished GUS-CCT1 fusion protein under blue light, whereas GUS-CCT1 fusion protein was stable in the fin219-2 mutant background (fin219-2/GUS-CCT1). Moreover, FIN219 strongly interacted with COP1 under blue light, and methyl JA (MeJA) treatment enhanced the interaction between FIN219 and GUS-CCT1 under blue light. Furthermore, FIN219 level affected GUS-CCT1 seedling responses such as anthocyanin accumulation and bacterial resistance under various light conditions and MeJA treatment. Thus, FIN219/JAR1 and CRY1 antagonize each other to modulate photomorphogenic development of seedlings and stress responses in Arabidopsis. PMID:29561841
Chen, Huai-Ju; Fu, Tsu-Yu; Yang, Shao-Li; Hsieh, Hsu-Liang
2018-03-01
Plant development is affected by the integration of light and phytohormones, including jasmonates (JAs). To address the molecular mechanisms of possible interactions between blue light and JA signaling in Arabidopsis thaliana, we used molecular and transgenic approaches to understand the regulatory relationships between FAR-RED INSENSITIVE 219 (FIN219)/JASMONATE RESISTANT1 (JAR1) and the blue-light photoreceptor cryptochrome1 (CRY1). FIN219 overexpression in the wild type resulted in a short-hypocotyl phenotype under blue light. However, FIN219 overexpression in cry1, cry2 and cry1cry2 double mutant backgrounds resulted in phenotypes similar to their respective mutant backgrounds, which suggests that FIN219 function may require blue light photoreceptors. Intriguingly, FIN219 overexpression in transgenic plants harboring ectopic expression of the C terminus of CRY1 (GUS-CCT1), which exhibits a hypersensitive short-hypocotyl phenotype in all light conditions including darkness, led to a rescued phenotype under all light conditions except red light. Further expression studies showed mutual suppression between FIN219 and CRY1 under blue light. Strikingly, FIN219 overexpression in GUS-CCT1 transgenic lines (FIN219-OE/GUS-CCT1) abolished GUS-CCT1 fusion protein under blue light, whereas GUS-CCT1 fusion protein was stable in the fin219-2 mutant background (fin219-2/GUS-CCT1). Moreover, FIN219 strongly interacted with COP1 under blue light, and methyl JA (MeJA) treatment enhanced the interaction between FIN219 and GUS-CCT1 under blue light. Furthermore, FIN219 level affected GUS-CCT1 seedling responses such as anthocyanin accumulation and bacterial resistance under various light conditions and MeJA treatment. Thus, FIN219/JAR1 and CRY1 antagonize each other to modulate photomorphogenic development of seedlings and stress responses in Arabidopsis.
Transonic static and dynamic stability characteristics of a finned projectile configuration
NASA Technical Reports Server (NTRS)
Boyden, R. P.; Brooks, C. W., Jr.; Davenport, E. E.
1978-01-01
Static and dynamic stability tests were made of a finned projectile configuration with the aft-mounted fins arranged in a cruciform pattern. The tests were made at free stream Mach numbers of 0.7, 0.9, 1.1, and 1.2 in the Langley 8-foot transonic pressure tunnel. Some of the parameters measured during the tests were lift, drag, pitching moment, pitch damping, and roll damping. Configurations tested included the body with undeflected fins, the body with various fin deflections for control, and the body with fins removed. Theoretical estimates of the stability derivatives were made for the fins on configuration.
Flow structure of natural dehumidification over a horizontal finned-tube
NASA Astrophysics Data System (ADS)
Hirbodi, Kamran; Yaghoubi, Mahmood
2016-08-01
In the present study, structure of water drops formation, growth, coalescence and departure over a horizontal finned-tube during natural dehumidification is investigated experimentally. Starting time of repelling the drops as well as heat transfer rate and the rate of dripping condensates in quasi-steady-state conditions are presented. Furthermore, cold airflow pattern around the horizontal finned-tube is visualized by using smoke generation scheme during natural dehumidification process. The finned-tube has a length of 300 mm, and inner and outer fin diameters, fin thickness and fin spacing are 25.4, 56, 0.4 and 2 mm, respectively. The tests are conducted in an insulated control room with dimensions of 5.8 m × 3 m × 4 m. Ambient air temperature, relative humidity and fin base temperature are selected from 25 to 35 °C, from 40 to 70 % and from 4 to 8 °C, respectively. Observations show that natural condensation from humid air over the test case is completely dropwise. Droplets only form on the edge of the fin and lateral fin surfaces remain almost dry. Dehumidification process over the tested finned-tube is divided into four stages; nucleation, formation, growth and departure of drops. It is also observed that the condensate inundation leaves the tube bottom in the form of droplets. Smoke visualization depicts that humid airflows downward around the cold finned-tube surface without noticeable turbulence and separation in the initial stages of dehumidification process. But the airflow has some disturbances in the intermediate stage and especially during drop departure on the edge of the fins.
NASA Astrophysics Data System (ADS)
Terry, K. N.; Turner, V.; Hackett, E.
2017-12-01
Aquatic animals' morphology provides inspiration for human technological developments, as their bodies have evolved and become adapted for efficient swimming. Lemon sharks exhibit a uniquely large second dorsal fin that is nearly the same size as the first fin, the hydrodynamic role of which is unknown. This experimental study looks at the drag forces on a scale model of the Lemon shark's unique two-fin configuration in comparison to drag forces on a more typical one-fin configuration. The experiments were performed in a recirculating water flume, where the wakes behind the scale models are measured using particle image velocimetry. The experiments are performed at three different flow speeds for both fin configurations. The measured instantaneous 2D distributions of the streamwise and wall-normal velocity components are ensemble averaged to generate streamwise velocity vertical profiles. In addition, velocity deficit profiles are computed from the difference between these mean streamwise velocity profiles and the free stream velocity, which is computed based on measured flow rates during the experiments. Results show that the mean velocities behind the fin and near the fin tip are smallest and increase as the streamwise distance from the fin tip increases. The magnitude of velocity deficits increases with increasing flow speed for both fin configurations, but at all flow speeds, the two-fin configurations generate larger velocity deficits than the one-fin configurations. Because the velocity deficit is directly proportional to the drag force, these results suggest that the two-fin configuration produces more drag.
Fully-Implicit Navier-Stokes (FIN-S)
NASA Technical Reports Server (NTRS)
Kirk, Benjamin S.
2010-01-01
FIN-S is a SUPG finite element code for flow problems under active development at NASA Lyndon B. Johnson Space Center and within PECOS: a) The code is built on top of the libMesh parallel, adaptive finite element library. b) The initial implementation of the code targeted supersonic/hypersonic laminar calorically perfect gas flows & conjugate heat transfer. c) Initial extension to thermochemical nonequilibrium about 9 months ago. d) The technologies in FIN-S have been enhanced through a strongly collaborative research effort with Sandia National Labs.
Correlated evolution of body and fin morphology in the cichlid fishes.
Feilich, Kara L
2016-10-01
Body and fin shapes are chief determinants of swimming performance in fishes. Different configurations of body and fin shapes can suit different locomotor specializations. The success of any configuration is dependent upon the hydrodynamic interactions between body and fins. Despite the importance of body-fin interactions for swimming, there are few data indicating whether body and fin configurations evolve in concert, or whether these structures vary independently. The cichlid fishes are a diverse family whose well-studied phylogenetic relationships make them ideal for the study of macroevolution of ecomorphology. This study measured body, and caudal and median fin morphology from radiographs of 131 cichlid genera, using morphometrics and phylogenetic comparative methods to determine whether these traits exhibit correlated evolution. Partial least squares canonical analysis revealed that body, caudal fin, dorsal fin, and anal fin shapes all exhibited strong correlated evolution consistent with locomotor ecomorphology. Major patterns included the evolution of deep body profiles with long fins, suggestive of maneuvering specialization; and the evolution of narrow, elongate caudal peduncles with concave tails, a combination that characterizes economical cruisers. These results demonstrate that body shape evolution does not occur independently of other traits, but among a suite of other morphological changes that augment locomotor specialization. © 2016 The Author(s). Evolution © 2016 The Society for the Study of Evolution.
Undulating fins produce off-axis thrust and flow structures.
Neveln, Izaak D; Bale, Rahul; Bhalla, Amneet Pal Singh; Curet, Oscar M; Patankar, Neelesh A; MacIver, Malcolm A
2014-01-15
While wake structures of many forms of swimming and flying are well characterized, the wake generated by a freely swimming undulating fin has not yet been analyzed. These elongated fins allow fish to achieve enhanced agility exemplified by the forward, backward and vertical swimming capabilities of knifefish, and also have potential applications in the design of more maneuverable underwater vehicles. We present the flow structure of an undulating robotic fin model using particle image velocimetry to measure fluid velocity fields in the wake. We supplement the experimental robotic work with high-fidelity computational fluid dynamics, simulating the hydrodynamics of both a virtual fish, whose fin kinematics and fin plus body morphology are measured from a freely swimming knifefish, and a virtual rendering of our robot. Our results indicate that a series of linked vortex tubes is shed off the long edge of the fin as the undulatory wave travels lengthwise along the fin. A jet at an oblique angle to the fin is associated with the successive vortex tubes, propelling the fish forward. The vortex structure bears similarity to the linked vortex ring structure trailing the oscillating caudal fin of a carangiform swimmer, though the vortex rings are distorted because of the undulatory kinematics of the elongated fin.
Cross-species functional diversity within the PIN auxin efflux protein family
DOE Office of Scientific and Technical Information (OSTI.GOV)
O'Connor, Devin Lee; Elton, Samuel; Ticchiarelli, Fabrizio
In Arabidopsis, development during flowering is coordinated by transport of the hormone auxin mediated by polar-localized PIN-FORMED1 (AtPIN1). However Arabidopsis has lost a PIN clade sister to AtPIN1, Sister-of-PIN1 (SoPIN1), which is conserved in flowering plants. Here, we previously proposed that the AtPIN1 organ initiation and vein patterning functions are split between the SoPIN1 and PIN1 clades in grasses. Here we show that in the grass Brachypodium sopin1 mutants have organ initiation defects similar to Arabidopsis atpin1, while loss of PIN1 function in Brachypodium has little effect on organ initiation but alters stem growth. Heterologous expression of Brachypodium SoPIN1 andmore » PIN1b in Arabidopsis provides further evidence of functional specificity. SoPIN1 but not PIN1b can mediate flower formation in null atpin1 mutants, although both can complement a missense allele. The behavior of SoPIN1 and PIN1b in Arabidopsis illustrates how membrane and tissue-level accumulation, transport activity, and interaction contribute to PIN functional specificity.« less
Cross-species functional diversity within the PIN auxin efflux protein family
O'Connor, Devin Lee; Elton, Samuel; Ticchiarelli, Fabrizio; ...
2017-10-24
In Arabidopsis, development during flowering is coordinated by transport of the hormone auxin mediated by polar-localized PIN-FORMED1 (AtPIN1). However Arabidopsis has lost a PIN clade sister to AtPIN1, Sister-of-PIN1 (SoPIN1), which is conserved in flowering plants. Here, we previously proposed that the AtPIN1 organ initiation and vein patterning functions are split between the SoPIN1 and PIN1 clades in grasses. Here we show that in the grass Brachypodium sopin1 mutants have organ initiation defects similar to Arabidopsis atpin1, while loss of PIN1 function in Brachypodium has little effect on organ initiation but alters stem growth. Heterologous expression of Brachypodium SoPIN1 andmore » PIN1b in Arabidopsis provides further evidence of functional specificity. SoPIN1 but not PIN1b can mediate flower formation in null atpin1 mutants, although both can complement a missense allele. The behavior of SoPIN1 and PIN1b in Arabidopsis illustrates how membrane and tissue-level accumulation, transport activity, and interaction contribute to PIN functional specificity.« less
Establishment of a biomimetic device based on tri-layer polymer actuators--propulsion fins.
Alici, Gursel; Spinks, Geoffrey; Huynh, Nam N; Sarmadi, Laleh; Minato, Rick
2007-06-01
We propose to use bending type tri-layer polymer actuators as propulsion fins for a biomimetic device consisting of a rigid body, like a box fish having a carapace, and paired fins running through the rigid body, like a fish having pectoral fins. The fins or polymer bending actuators can be considered as individually controlled flexible membranes. Each fin is activated with sinusoidal inputs such that there is a phase lag between the movements of successive fins to create enough thrust force for propulsion. Eight fins with 0.125 aspect ratio have been used along both sides of the rigid body to move the device in the direction perpendicular to the longitudinal axis of the body. The designed device with the paired fins was successfully tested, moving in an organic solution consisting of solvent, propylene carbonate (PC), and electrolyte. The design procedure outlined in this study is offered as a guide to making functional devices based on polymer actuators and sensors.
Ge-cap quantum-well bulk FinFET for 5 nm node CMOS integration
NASA Astrophysics Data System (ADS)
Dwi Kurniawan, Erry; Peng, Kang-Hui; Yang, Shang-Yi; Yang, Yi-Yun; Thirunavukkarasu, Vasanthan; Lin, Yu-Hsien; Wu, Yung-Chun
2018-04-01
We propose the use of Ge-cap quantum-well (QW) bulk FinFET for 5 nm CMOS integration, which is a Si channel wrapped with Ge around three sides of the fin channel. The simulation results show that the Ge-cap FinFET structure demonstrates better performance than pure Si, pure Ge, and Si-cap FinFET structures. By optimizing Si fin width and Ge-cap thickness, the on-state current of nFET and pFET can also be symmetric without changing the total fin width (F Wp = F Wn). The electrons in Ge-cap nFinFET concentrate in the Si channel because of QWs formed in the lowest conduction band of the Ge and Si heterostructure, while the holes in Ge-cap pFinFET prefer to stay in Ge surfaces owing to QWs formed in the Ge valence band. The physics studies of this device have made the design rules relevant for the application of the CMOS inverter and static random access memory (SRAM) application technology.
Effects of ultra-thin Si-fin body widths upon SOI PMOS FinFETs
NASA Astrophysics Data System (ADS)
Liaw, Yue-Gie; Chen, Chii-Wen; Liao, Wen-Shiang; Wang, Mu-Chun; Zou, Xuecheng
2018-05-01
Nano-node tri-gate FinFET devices have been developed after integrating a 14 Å nitrided gate oxide upon the silicon-on-insulator (SOI) wafers established on an advanced CMOS logic platform. These vertical double gate (FinFET) devices with ultra-thin silicon fin (Si-fin) widths ranging from 27 nm to 17 nm and gate length down to 30 nm have been successfully developed with a 193 nm scanner lithography tool. Combining the cobalt fully silicidation and the CESL strain technology beneficial for PMOS FinFETs was incorporated into this work. Detailed analyses of Id-Vg characteristics, threshold voltage (Vt), and drain-induced barrier lowering (DIBL) illustrate that the thinnest 17 nm Si-fin width FinFET exhibits the best gate controllability due to its better suppression of short channel effect (SCE). However, higher source/drain resistance (RSD), channel mobility degradation due to dry etch steps, or “current crowding effect” will slightly limit its transconductance (Gm) and drive current.
Morphogenesis and evolution of vertebrate appendicular muscle
HAINES, LYNN; CURRIE, PETER D.
2001-01-01
Two different modes are utilised by vertebrate species to generate the appendicular muscle present within fins and limbs. Primitive Chondricthyan or cartilaginous fishes use a primitive mode of muscle formation to generate the muscle of the fins. Direct epithelial myotomal extensions invade the fin and generate the fin muscles while remaining in contact with the myotome. Embryos of amniotes such as chick and mouse use a similar mechanism to that deployed in the bony teleost species, zebrafish. Migratory mesenchymal myoblasts delaminate from fin/limb level somites, migrate to the fin/limb field and differentiate entirely within the context of the fin/limb bud. Migratory fin and limb myoblasts express identical genes suggesting that they possess both morphogenetic and molecular identity. We conclude that the mechanisms controlling tetrapod limb muscle formation arose prior to the Sarcopterygian or tetrapod radiation. PMID:11523824
NASA Technical Reports Server (NTRS)
Hartman, Edward R.; Johnston, Patrick J.
1987-01-01
An experimental and theoretical investigation of the longitudinal and lateral-directional stability and control of an axisymmetric cruciform-finned missile has been conducted at Mach 6. The angle-of-attack range extended from 20 to 65 deg to encompass maximum lift. Longitudinal stability, performance, and trim could be accurately predicted with the fins at a fin roll angle of 0 deg but not when the fins were at a fin roll angle of 45 deg. At this roll angle, windward fin choking occurred at angles of attack above 50 deg and reduced the effectiveness of the fins and caused pitch-up.
Roch, S; Behrmann-Godel, J; Brinker, A
2015-01-21
The unusual yellow-finned morph of European perch Perca fluviatilis found in Lake Constance suffers more severely from macroparasite infections, including the tapeworm Triaenophorus nodulosus and the gill worm Ancyrocephalus percae, than conspecifics elsewhere. Microsatellite analysis of yellow-finned P. fluviatilis and red-finned variant recently discovered in Lake Constance revealed significant genetic differentiation. Red-finned P. fluviatilis and fish with mixed fin colour, suggested backcrosses between red and yellow-finned colour morphs, exhibit better resilience to parasite infection, suggesting that the inability of the yellow-finned morph to reject macroparasites may have a genetic basis. © 2015 The Fisheries Society of the British Isles.
Molnar, Julia L; Johnston, Peter S; Esteve-Altava, Borja; Diogo, Rui
2017-04-01
As a member of the most basal clade of extant ray-finned fishes (actinopterygians) and of one of the most basal clades of osteichthyans (bony fishes + tetrapods), Polypterus can provide insights into the ancestral anatomy of both ray-finned and lobe-finned fishes, including those that gave rise to tetrapods. The pectoral fin of Polypterus has been well described but, surprisingly, neither the bones nor the muscles of the pelvic fin are well known. We stained and dissected the pelvic fin of Polypterus senegalus and Polypterus delhezi to offer a detailed description of its musculoskeletal anatomy. In addition to the previously described adductor and abductor muscles, we found preaxial and postaxial muscles similar to those in the pectoral fin of members of this genus. The presence of pre- and postaxial muscles in both the pectoral and pelvic fins of Polypterus, combined with recent descriptions of similar muscles in the lobe-finned fishes Latimeria and Neoceratodus, suggests that they were present in the most recent common ancestor of bony fishes. These results have crucial implications for the evolution of appendicular muscles in both fish and tetrapods. © 2016 Anatomical Society.
Curvature-induced stiffening of a fish fin.
Nguyen, Khoi; Yu, Ning; Bandi, Mahesh M; Venkadesan, Madhusudhan; Mandre, Shreyas
2017-05-01
How fish modulate their fin stiffness during locomotive manoeuvres remains unknown. We show that changing the fin's curvature modulates its stiffness. Modelling the fin as bendable bony rays held together by a membrane, we deduce that fin curvature is manifested as a misalignment of the principal bending axes between neighbouring rays. An external force causes neighbouring rays to bend and splay apart, and thus stretches the membrane. This coupling between bending the rays and stretching the membrane underlies the increase in stiffness. Using three-dimensional reconstruction of a mackerel ( Scomber japonicus ) pectoral fin for illustration, we calculate the range of stiffnesses this fin is expected to span by changing curvature. The three-dimensional reconstruction shows that, even in its geometrically flat state, a functional curvature is embedded within the fin microstructure owing to the morphology of individual rays. As the ability of a propulsive surface to transmit force to the surrounding fluid is limited by its stiffness, the fin curvature controls the coupling between the fish and its surrounding fluid. Thereby, our results provide mechanical underpinnings and morphological predictions for the hypothesis that the spanned range of fin stiffnesses correlates with the behaviour and the ecological niche of the fish. © 2017 The Author(s).
Curvature-induced stiffening of a fish fin
2017-01-01
How fish modulate their fin stiffness during locomotive manoeuvres remains unknown. We show that changing the fin's curvature modulates its stiffness. Modelling the fin as bendable bony rays held together by a membrane, we deduce that fin curvature is manifested as a misalignment of the principal bending axes between neighbouring rays. An external force causes neighbouring rays to bend and splay apart, and thus stretches the membrane. This coupling between bending the rays and stretching the membrane underlies the increase in stiffness. Using three-dimensional reconstruction of a mackerel (Scomber japonicus) pectoral fin for illustration, we calculate the range of stiffnesses this fin is expected to span by changing curvature. The three-dimensional reconstruction shows that, even in its geometrically flat state, a functional curvature is embedded within the fin microstructure owing to the morphology of individual rays. As the ability of a propulsive surface to transmit force to the surrounding fluid is limited by its stiffness, the fin curvature controls the coupling between the fish and its surrounding fluid. Thereby, our results provide mechanical underpinnings and morphological predictions for the hypothesis that the spanned range of fin stiffnesses correlates with the behaviour and the ecological niche of the fish. PMID:28566508
NASA Astrophysics Data System (ADS)
English, Ian; Curet, Oscar
2016-11-01
Lighthill and Blake's 1990 momentum enhancement theory suggests there is a multiplicative propulsive effect linked to the ratio of body and fin heights in Gymnotiform and Balistiform swimmers, which propel themselves using multi-rayed undulating fins while keeping their bodies mostly rigid. Proof of such a momentum enhancement could have a profound effect on unmanned underwater vehicle design and shed light on the evolutionary advantage to body-fin ratios found in nature, shown as optimal for momentum enhancement in Lighthill and Blake's theory. A robotic ribbon fin with twelve independent fin rays, elastic fin membrane, and a body of adjustable height was developed specifically to experimentally test momentum enhancement. Thrust tests for various body heights were conducted in a recirculating flow tank at different flow speeds and fin flapping frequencies. When comparing thrust at different body heights, flow speeds, and frequencies to a 'no-body' thrust test case at each frequency and flow speed, data indicate there is no momentum enhancement factor due to the presence of a body on top of an undulating fin. This suggests that if there is a benefit to a specific ratio between body and fin height, it is not due to momentum enhancement.
Pin1At regulates PIN1 polar localization and root gravitropism.
Xi, Wanyan; Gong, Ximing; Yang, Qiaoyun; Yu, Hao; Liou, Yih-Cherng
2016-01-21
Root gravitropism allows plants to establish root systems and its regulation depends on polar auxin transport mediated by PIN-FORMED (PIN) auxin transporters. PINOID (PID) and PROTEIN PHOSPHATASE 2A (PP2A) act antagonistically on reversible phosphorylation of PINs. This regulates polar PIN distribution and auxin transport. Here we show that a peptidyl-prolyl cis/trans isomerase Pin1At regulates root gravitropism. Downregulation of Pin1At suppresses root agravitropic phenotypes of pp2aa and 35S:PID, while overexpression of Pin1At affects root gravitropic responses and enhances the pp2aa agravitropic phenotype. Pin1At also affects auxin transport and polar localization of PIN1 in stele cells, which is mediated by PID and PP2A. Furthermore, Pin1At catalyses the conformational change of the phosphorylated Ser/Thr-Pro motifs of PIN1. Thus, Pin1At mediates the conformational dynamics of PIN1 and affects PID- and PP2A-mediated regulation of PIN1 polar localization, which correlates with the regulation of root gravitropism.
Pin1At regulates PIN1 polar localization and root gravitropism
Xi, Wanyan; Gong, Ximing; Yang, Qiaoyun; Yu, Hao; Liou, Yih-Cherng
2016-01-01
Root gravitropism allows plants to establish root systems and its regulation depends on polar auxin transport mediated by PIN-FORMED (PIN) auxin transporters. PINOID (PID) and PROTEIN PHOSPHATASE 2A (PP2A) act antagonistically on reversible phosphorylation of PINs. This regulates polar PIN distribution and auxin transport. Here we show that a peptidyl-prolyl cis/trans isomerase Pin1At regulates root gravitropism. Downregulation of Pin1At suppresses root agravitropic phenotypes of pp2aa and 35S:PID, while overexpression of Pin1At affects root gravitropic responses and enhances the pp2aa agravitropic phenotype. Pin1At also affects auxin transport and polar localization of PIN1 in stele cells, which is mediated by PID and PP2A. Furthermore, Pin1At catalyses the conformational change of the phosphorylated Ser/Thr-Pro motifs of PIN1. Thus, Pin1At mediates the conformational dynamics of PIN1 and affects PID- and PP2A-mediated regulation of PIN1 polar localization, which correlates with the regulation of root gravitropism. PMID:26791759
NASA Astrophysics Data System (ADS)
Primeaux, Philip A.; Zhang, Bin; Zhang, Xiaoman; Miller, Jacob; Meng, W. J.; KC, Pratik; Moore, Arden L.
2017-02-01
Microscale fin array structures were replicated onto surfaces of aluminum 1100 and aluminum 6061 alloy (Al1100/Al6061) sheet metals through room-temperature instrumented roll molding. Aluminum-based micro fin arrays were replicated at room temperature, and the fabrication process is one with high throughput and low cost. One-dimensional (1D) micro fin arrays were made through one-pass rolling, while two-dimensional (2D) micro fin arrays were made by sequential 90° cross rolling with the same roller sleeve. For roll molding of 1D micro fins, fin heights greater than 600 µm were achieved and were shown to be proportional to the normal load force per feature width. At a given normal load force, the fin height was further shown to scale inversely with the hardness of the sheet metal. For sequential 90° cross rolling, morphologies of roll molded 2D micro fin arrays were examined, which provided clues to understand how plastic deformation occurred under cross rolling conditions. A series of pool boiling experiments on low profile Al micro fin array structures were performed within Novec 7100, a widely used commercial dielectric coolant. Results for both horizontal and vertical surface orientations show that roll molded Al micro fin arrays can increase heat flux at fixed surface temperature as compared to un-patterned Al sheet. The present results further suggest that many factors beyond just increased surface area can influence heat transfer performance, including surface finish and the important multiphase transport mechanisms in and around the fin geometry. These factors must also be considered when designing and optimizing micro fin array structures for heat transfer applications.
Champagne, C.E.; Austin, J.D.; Jelks, H.L.; Jordan, F.
2008-01-01
Advent of the polymerase chain reaction (PCR) has allowed conservation biologists to use small portions of tissue to obtain genetic material for population genetic and taxonomic study. Fin clips are used extensively in large-sized fishes, but it is unclear how clipping enough fin tissue for genetic analysis will affect survival of smaller fishes such as minnows and darters, which are among the most threatened organisms in North America. We tested for effects of fin clipping on survival and swimming performance of non-threatened Brown Darters (Etheostoma edwini) in order to justify similar tissue collection in co-occurring endangered Okaloosa Darters (E. okaloosae). We collected 48 E. edwini from a small stream in northwest Florida, transported them to the laboratory, and randomly assigned them to one of three experimental groups: control, entire right pectoral fin removed, or rear half of caudal fin removed. Successful amplification of DNA indicated that our fin clips were large enough for genetic analysis using PCR. No mortality occurred during a two-month observation period. Fin regeneration was almost complete and we could not visually distinguish clipped fins from control fins after two months. We then randomly assigned fish into the same three experimental groups, clipped fins, and evaluated their ability to hold position at 20 cm/sec in an experimental flow chamber. Neither fish size nor treatment type affected position-holding behavior. Fin clipping does not adversely affect survival and swimming performance of E. edwini maintained in the laboratory. Additional research on the effects of fin clipping on small-sized fishes should be conducted in the field to evaluate survival under natural conditions. ?? 2008 by the American Society of Ichthyologists and Herpetologists.
Methylmercury in dried shark fins and shark fin soup from American restaurants.
Nalluri, Deepthi; Baumann, Zofia; Abercrombie, Debra L; Chapman, Demian D; Hammerschmidt, Chad R; Fisher, Nicholas S
2014-10-15
Consumption of meat from large predatory sharks exposes human consumers to high levels of toxic monomethylmercury (MMHg). There also have been claims that shark fins, and hence the Asian delicacy shark fin soup, contain harmful levels of neurotoxic chemicals in combination with MMHg, although concentrations of MMHg in shark fins are unknown. We measured MMHg in dried, unprocessed fins (n=50) of 13 shark species that occur in the international trade of dried shark fins as well as 50 samples of shark fin soup prepared by restaurants from around the United States. Concentrations of MMHg in fins ranged from 9 to 1720 ng/g dry wt. MMHg in shark fin soup ranged from <0.01 to 34 ng/mL, with MMHg averaging 62 ± 7% of total Hg. The highest concentrations of MMHg and total Hg were observed in both fins and soup from large, high trophic level sharks such as hammerheads (Sphyrna spp.). Consumption of a 240 mL bowl of shark fin soup containing the average concentration of MMHg (4.6 ng/mL) would result in a dose of 1.1 μg MMHg, which is 16% of the U.S. EPA's reference dose (0.1 μg MMHg per 1 kg per day in adults) of 7.4 μg per day for a 74 kg person. If consumed, the soup containing the highest measured MMHg concentration would exceed the reference dose by 17%. While shark fin soup represents a potentially important source of MMHg to human consumers, other seafood products, particularly the flesh of apex marine predators, contain much higher MMHg concentrations and can result in substantially greater exposures of this contaminant for people. Copyright © 2014 Elsevier B.V. All rights reserved.
NASA Technical Reports Server (NTRS)
Curry, Donald M.; Lewis, Ronald K.; Hagen, Jeffrey D.
2002-01-01
An X-38 Crew Return Vehicle Seal Development is presented. The contents include: 1) X-38 Crew Return Vehicle; 2) X-38 TPS Configuration; 3) X-38 Seal Locations; 4) X-38 Rudder/Fin Seal Assembly; 5) Baseline X-38 Rudder/Fin Seal Design; 6) Rudder/Fin Seal to Bracket Assembly; 7) X-38 Rudder/Fin Vertical Rub Surface Inconel-0.10 inches; 8) X-38 Rudder/Fin Seal Analysis; 9) Seal Analysis Model; and 10) Governing Differential Equations for Equilibrium Thermal Assumption. The X-38 Rudder/Fin Seal temperature and pressure properties are also given.
A biorobotic pectoral fin for autonomous undersea vehicles.
Tangorra, James L; Davidson, S Naomi; Madden, Peter G; Lauder, George V; Hunter, Ian W
2006-01-01
A biorobotic fin for autonomous undersea vehicles (AUVs) was developed based on studies of the anatomy, kinematics, and hydrodynamics of the bluegill sunfish pectoral fin. The biorobotic fin was able to produce many of the complex fin motions used by the sunfish during steady swimming and was used to investigate mechanisms of thrust production and control. This biorobotic fin is an excellent experimental tool and is an important first step towards developing propulsive devices that give AUVs maneuvering characteristics that match and exceed those of highly maneuverable fish.
Maia, Anabela; Wilga, Cheryl D
2013-11-01
Stability and procured instability characterize two opposing types of swimming, steady and maneuvering, respectively. Fins can be used to manipulate flow to adjust stability during swimming maneuvers either actively using muscle control or passively by structural control. The function of the dorsal fins during turning maneuvering in two shark species with different swimming modes is investigated here using musculoskeletal anatomy and muscle function. White-spotted bamboo sharks are a benthic species that inhabits complex reef habitats and thus have high requirements for maneuverability. Spiny dogfish occupy a variety of coastal and continental shelf habitats and spend relatively more time cruising in open water. These species differ in dorsal fin morphology and fin position along the body. Bamboo sharks have a larger second dorsal fin area and proportionally more muscle insertion into both dorsal fins. The basal and radial pterygiophores are plate-like structures in spiny dogfish and are nearly indistinguishable from one another. In contrast, bamboo sharks lack basal pterygiophores, while the radial pterygiophores form two rows of elongated rectangular elements that articulate with one another. The dorsal fin muscles are composed of a large muscle mass that extends over the ceratotrichia overlying the radials in spiny dogfish. However, in bamboo sharks, the muscle mass is divided into multiple distinct muscles that insert onto the ceratotrichia. During turning maneuvers, the dorsal fin muscles are active in both species with no differences in onset between fin sides. Spiny dogfish have longer burst durations on the outer fin side, which is consistent with opposing resistance to the medium. In bamboo sharks, bilateral activation of the dorsal in muscles could also be stiffening the fin throughout the turn. Thus, dogfish sharks passively stiffen the dorsal fin structurally and functionally, while bamboo sharks have more flexible dorsal fins, which result from a steady swimming trade off. Copyright © 2013 Wiley Periodicals, Inc.
NASA Astrophysics Data System (ADS)
Taji, S. G.; Parishwad, G. V.; Sane, N. K.
2014-07-01
This paper presents results of the experimental study conducted on heated horizontal rectangular fin array under natural convection. The temperature mapping and the prediction of the flow patterns over the fin array with variable fin spacing is carried out. Dimensionless fin spacing to height (S/H) ratio is varied from 0.05 to 0.3 and length to height ratio (L/H) = 5 is kept constant. The heater input to the fin array assembly is varied from 25 to 100 W. The single chimney flow pattern is observed from 8 to 12 mm fin spacing. The end flow is choked below 6 mm fin spacing. The single chimney flow pattern changes to sliding or end flow choking at 6 mm fin spacing. The average heat transfer coefficient (ha) is very small (2.52-5.78 W/m2 K) at 100 W for S = 5-12 mm. The ha is very small (1.12-1.8 W/m2 K) at 100 W for 2-4 mm fin spacing due to choked fin array end condition. The end flow is not sufficient to reach up to central portion of fin array and in the middle portion there is an unsteady down and up flow pattern resulting in sliding chimney. The central bottom portion of fin array channel does not contribute much in heat dissipation for S = 2-4 mm. The ha has significantly improved at higher spacing as compared to lower spacing region. The single chimney flow pattern is preferred from heat transfer point of view. The optimum spacing is confirmed in the range of 8-10 mm. The average heat transfer results are compared with previous literature and showed similar trend and satisfactory agreement. An empirical equation has been proposed to correlate the average Nusselt number as a function of Grashof number and fin spacing to height ratio. The average error for this equation is -0.32 %.
Molecular mechanisms underlying the exceptional adaptations of batoid fins.
Nakamura, Tetsuya; Klomp, Jeff; Pieretti, Joyce; Schneider, Igor; Gehrke, Andrew R; Shubin, Neil H
2015-12-29
Extreme novelties in the shape and size of paired fins are exemplified by extinct and extant cartilaginous and bony fishes. Pectoral fins of skates and rays, such as the little skate (Batoid, Leucoraja erinacea), show a strikingly unique morphology where the pectoral fin extends anteriorly to ultimately fuse with the head. This results in a morphology that essentially surrounds the body and is associated with the evolution of novel swimming mechanisms in the group. In an approach that extends from RNA sequencing to in situ hybridization to functional assays, we show that anterior and posterior portions of the pectoral fin have different genetic underpinnings: canonical genes of appendage development control posterior fin development via an apical ectodermal ridge (AER), whereas an alternative Homeobox (Hox)-Fibroblast growth factor (Fgf)-Wingless type MMTV integration site family (Wnt) genetic module in the anterior region creates an AER-like structure that drives anterior fin expansion. Finally, we show that GLI family zinc finger 3 (Gli3), which is an anterior repressor of tetrapod digits, is expressed in the posterior half of the pectoral fin of skate, shark, and zebrafish but in the anterior side of the pelvic fin. Taken together, these data point to both highly derived and deeply ancestral patterns of gene expression in skate pectoral fins, shedding light on the molecular mechanisms behind the evolution of novel fin morphologies.
Molecular mechanisms underlying the exceptional adaptations of batoid fins
Nakamura, Tetsuya; Klomp, Jeff; Pieretti, Joyce; Schneider, Igor; Gehrke, Andrew R.; Shubin, Neil H.
2015-01-01
Extreme novelties in the shape and size of paired fins are exemplified by extinct and extant cartilaginous and bony fishes. Pectoral fins of skates and rays, such as the little skate (Batoid, Leucoraja erinacea), show a strikingly unique morphology where the pectoral fin extends anteriorly to ultimately fuse with the head. This results in a morphology that essentially surrounds the body and is associated with the evolution of novel swimming mechanisms in the group. In an approach that extends from RNA sequencing to in situ hybridization to functional assays, we show that anterior and posterior portions of the pectoral fin have different genetic underpinnings: canonical genes of appendage development control posterior fin development via an apical ectodermal ridge (AER), whereas an alternative Homeobox (Hox)–Fibroblast growth factor (Fgf)–Wingless type MMTV integration site family (Wnt) genetic module in the anterior region creates an AER-like structure that drives anterior fin expansion. Finally, we show that GLI family zinc finger 3 (Gli3), which is an anterior repressor of tetrapod digits, is expressed in the posterior half of the pectoral fin of skate, shark, and zebrafish but in the anterior side of the pelvic fin. Taken together, these data point to both highly derived and deeply ancestral patterns of gene expression in skate pectoral fins, shedding light on the molecular mechanisms behind the evolution of novel fin morphologies. PMID:26644578
Hydrodynamics of a freely movable flexible fin near the ground
NASA Astrophysics Data System (ADS)
Jeong, Young Dal; Lee, Jae Hwa
2017-11-01
In the present study, a freely movable flexible fin is numerically modelled to investigate the flapping dynamics of the fin near the ground in a Poiseuille flow. A leading edge of the fin is fixed in the streamwise direction, whereas the lateral motion is spontaneously determined by hydrodynamic interaction between the fin and surrounding fluid. When the fin is initially positioned at yo, the fin passively migrates toward another wall-normal position for an equilibrium state by the interaction between passively flapping flexible body and ground. At the equilibrium position, the drag coefficient of the fin (CD) significantly decreases due to decaying of the flapping and low flow velocity and the fin can swim consistently without the time-averaged lateral force. Two distinctive behavior at the transient state (flapping and non-flapping migration modes) and three distinctive behaviors at the equilibrium state (deflected-straight, large- and small-amplitude flapping modes) are observed depending on the bending rigidity (γ) and mass ratio (μ) of the fin. The equilibrium position of the fin is investigated as a function of initial position (yo) , bending rigidity (γ) , mass ratio (μ) and the Reynolds number (Re). This research was supported by the National Research Foundation of Korea (NRF) funded by the Ministry of Education (NRF-2017R1D1A1A09000537) and the Ministry of Science, ICT & Future Planning (NRF-2017R1A5A1015311).
Fish Pectoral Fin Hydrodynamics; Part III: Low Dimensional Models via POD Analysis
NASA Astrophysics Data System (ADS)
Bozkurttas, M.; Madden, P.
2005-11-01
The highly complex kinematics of the pectoral fin and the resulting hydrodynamics does not lend itself easily to analysis based on simple notions of pitching/heaving/paddling kinematics or lift/drag based propulsive mechanisms. A more inventive approach is needed to dissect the fin gait and gain insight into the hydrodynamic performance of the pectoral fin. The focus of the current work is on the hydrodynamics of the pectoral fin of a bluegill sunfish in steady forward motion. The 3D, time-dependent fin kinematics is obtained via a stereo-videographic technique. We employ proper orthogonal decomposition to extract the essential features of the fin gait and then use CFD to examine the hydrodynamics of simplified gaits synthesized from the POD modes. The POD spectrum shows that the first two, three and five POD modes capture 55%, 67%, and 80% of the motion respectively. The first three modes are in particular highly distinct: Mode-1 is a ``cupping'' motion where the fin cups forward as it is abducted; Mode-2 is an ``expansion'' motion where the fin expands to present a larger area during adduction and finally Mode-3 involves a ``spanwise flick'' of the dorsal edge of the fin. Numerical simulation of flow past fin gaits synthesized from these modes lead to insights into the mechanisms of thrust production; these are discussed in detail.
Flow-structure Interaction Modeling of a Fish Caudal Fin during Steady Swimming
NASA Astrophysics Data System (ADS)
Liu, Geng; Geng, Biao; Zheng, Xudong; Xue, Qian; Dong, Haibo
2017-11-01
It's widely thought that the flexibilities of fish fins play critical roles in propulsive performance enhancement (such as thrust augment and efficiency improvement) in nature. In order to explore the formation mechanisms of the fish fin's flexible morphing and its hydrodynamic benefits as well, a high-fidelity flow-structure/membrane interaction modeling of the fish caudal fin is conducted in this work. Following the realistic configuration of the fish caudal fin, a thin membrane supported by a series of beams is constructed. The material properties of the membrane and the beams are reversely determined by the realistic fin morphing obtained from the high-speed videos and the high fidelity flow-structure interaction simulations. With the accurate material property, we investigate the interplay between structure, kinematics and fluid flow in caudal fin propulsion. Detailed analyses on the relationship between the flexural stiffness, fin morphing patterns, hydrodynamic forces and vortex dynamics are then conducted.
PNS predictions for supersonic/hypersonic flows over finned missile configurations
NASA Technical Reports Server (NTRS)
Bhutta, Bilal A.; Lewis, Clark H.
1992-01-01
Finned missile design entails accurate and computationally fast numerical techniques for predicting viscous flows over complex lifting configurations at small to moderate angles of attack and over Mach 3 to 15; these flows are often characterized by strong embedded shocks, so that numerical algorithms are also required to capture embedded shocks. The recent real-gas Flux Vector Splitting technique is here extended to investigate the Mach 3 flow over a typical finned missile configuration with/without side fin deflections. Elliptic grid-generation techniques for Mach 15 flows are shown to be inadequate for Mach 3 flows over finned configurations and need to be modified. Fin-deflection studies indicate that even small amounts of missile fin deflection can substantially modify vehicle aerodynamics. This 3D parabolized Navier-Stokes scheme is also extended into an efficient embedded algorithm for studying small axially separated flow regions due to strong fin and control surface deflections.
NASA Technical Reports Server (NTRS)
Iversen, J.; Moghadam, M.
1981-01-01
Forty-six different fins, which were members of twelve plan-form families, were tested. A two dimensional Boeing single element airfoil at an angle of attack of eight degrees and a sweepback angle of thirty-two was used to simulate a portion of the wing of a generator aircraft. Various free stream velocities were used to test any individual fin at its particular angle of attack. While the fin itself was mounted on the upper surface of the generator model, the angle of attack of each fin was varied until stall was reached and/or passed. The relative fin vortex strengths were measured in two ways. First, the maximum angular velocity of a four blade rotor placed in the fin vortex center was measured with the use of a stroboscope. Second, the maximum rolling moment on a following wing model placed in the fin vortex center was measured by a force balance.
The Influence of Culture on the International Management of Shark Finning
NASA Astrophysics Data System (ADS)
Dell'Apa, Andrea; Chad Smith, M.; Kaneshiro-Pineiro, Mahealani Y.
2014-08-01
Shark finning is prohibited in many countries, but high prices for fins from the Asian market help maintain the international black-market and poaching. Traditional shark fin bans fail to recognize that the main driver of fin exploitation is linked to cultural beliefs about sharks in traditional Chinese culture. Therefore, shark finning should be addressed considering the social science approach as part of the fishery management scheme. This paper investigates the cultural significance of sharks in traditional Chinese and Hawaiian cultures, as valuable examples of how specific differences in cultural beliefs can drive individuals' attitudes toward the property of shark finning. We suggest the use of a social science approach that can be useful in the design of successful education campaigns to help change individuals' attitudes toward shark fin consumption. Finally, alternative management strategies for commercial fishers are provided to maintain self-sustainability of local coastal communities.
The influence of culture on the international management of shark finning.
Dell'Apa, Andrea; Smith, M Chad; Kaneshiro-Pineiro, Mahealani Y
2014-08-01
Shark finning is prohibited in many countries, but high prices for fins from the Asian market help maintain the international black-market and poaching. Traditional shark fin bans fail to recognize that the main driver of fin exploitation is linked to cultural beliefs about sharks in traditional Chinese culture. Therefore, shark finning should be addressed considering the social science approach as part of the fishery management scheme. This paper investigates the cultural significance of sharks in traditional Chinese and Hawaiian cultures, as valuable examples of how specific differences in cultural beliefs can drive individuals' attitudes toward the property of shark finning. We suggest the use of a social science approach that can be useful in the design of successful education campaigns to help change individuals' attitudes toward shark fin consumption. Finally, alternative management strategies for commercial fishers are provided to maintain self-sustainability of local coastal communities.
A Method for Prevention of Screaming in Rocket Engines
NASA Technical Reports Server (NTRS)
Kerslake, W. R.; Male, T.
1954-01-01
Lateral and longitudinal combustion-pressure oscillations that occurred in screaming combustion of a 1000-pound-thrust rocket engine using white fuming nitric acid and JP-4 fuel as propellants were successfully prevented by means of longitudinal fins in the combustion chamber. Fin position was critical, and complete attenuation was achieved only when the fins were located in a zone approximately 8 to 16 inches from the injector. Fins located in other zones, that is, near the injector or far downstream from the injector, did not stop the oscillations. When oscillations occurred in finned chambers, the longitudinal mode seemed more dominant than the lateral mode; in chambers without fins, the lateral mode tended to be dominant. The lateral oscillation was distorted and its intensity diminished by the fins. Fins, however, did not affect the frequencies; the longitudinal frequency varied inversely with chamber length, and lateral frequencies varied only slightly from an average of 6000 cycles per second.
Underwater fin swimming in women with reference to fin selection.
Pendergast, D R; Mollendorf, J; Logue, C; Samimy, S
2003-01-01
Underwater swimmers use fins, which provide thrust to overcome drag and propel the diver. The type of fin used has been shown to affect diver performance, however data are lacking for women. The oxygen consumption (VdotO2) of swimming as a function of speed, velocity as a function of kick frequency, maximal speed (v), maximal VdotO2 and the maximal thrust were determined for 8 female divers swimming at 1.25 m depth in a 60 m annular pool. VdotO2 increased as a function of v as; 0.52 + -0.485 V + 2.85 V2 (r2 = 0.996) and 0.12 + 1.52 V +1.275 V2 (r2 = 0.999) for high (5 fins) and low (3 fins) groupings, respectively. Splits, vents and flanges did not significantly affect VdotO2. Kick frequency increased linearly with v, with unique slopes for each fin. Maximal VdotO2 was not affect by fin type (1.46 +/- 0.05 l/min). Velocities that could be stained aerobically were 0.60 +/- 0.02 m/sec on average, with the most flexible fin higher (0.71 m/sec). Maximal v averaged 0.87 +/- 0.03 m/sec, with the most rigid fin lower (0.77 m/sec). Maximal thrust was not affected by fin and averaged 104 +/- 9 N. It can be concluded that female divers preferred the most flexible fins, which were also the most economical. This is most likely due to low leg power, which could also explain the absence of differences in maximal thrust and velocity.
Heat exchanger with transpired, highly porous fins
Kutscher, Charles F.; Gawlik, Keith
2002-01-01
The heat exchanger includes a fin and tube assembly with increased heat transfer surface area positioned within a hollow chamber of a housing to provide effective heat transfer between a gas flowing within the hollow chamber and a fluid flowing in the fin and tube assembly. A fan is included to force a gas, such as air, to flow through the hollow chamber and through the fin and tube assembly. The fin and tube assembly comprises fluid conduits to direct the fluid through the heat exchanger, to prevent mixing with the gas, and to provide a heat transfer surface or pathway between the fluid and the gas. A heat transfer element is provided in the fin and tube assembly to provide extended heat transfer surfaces for the fluid conduits. The heat transfer element is corrugated to form fins between alternating ridges and grooves that define flow channels for directing the gas flow. The fins are fabricated from a thin, heat conductive material containing numerous orifices or pores for transpiring the gas out of the flow channel. The grooves are closed or only partially open so that all or substantially all of the gas is transpired through the fins so that heat is exchanged on the front and back surfaces of the fins and also within the interior of the orifices, thereby significantly increasing the available the heat transfer surface of the heat exchanger. The transpired fins also increase heat transfer effectiveness of the heat exchanger by increasing the heat transfer coefficient by disrupting boundary layer development on the fins and by establishing other beneficial gas flow patterns, all at desirable pressure drops.
Ramamurti, Ravi; Sandberg, William C; Löhner, Rainald; Walker, Jeffrey A; Westneat, Mark W
2002-10-01
Many fishes that swim with the paired pectoral fins use fin-stroke parameters that produce thrust force from lift in a mechanism of underwater flight. These locomotor mechanisms are of interest to behavioral biologists, biomechanics researchers and engineers. In the present study, we performed the first three-dimensional unsteady computations of fish swimming with oscillating and deforming fins. The objective of these computations was to investigate the fluid dynamics of force production associated with the flapping aquatic flight of the bird wrasse Gomphosus varius. For this computational work, we used the geometry of the wrasse and its pectoral fin, and previously measured fin kinematics, as the starting points for computational investigation of three-dimensional (3-D) unsteady fluid dynamics. We performed a 3-D steady computation and a complete set of 3-D quasisteady computations for a range of pectoral fin positions and surface velocities. An unstructured, grid-based, unsteady Navier-Stokes solver with automatic adaptive remeshing was then used to compute the unsteady flow about the wrasse through several complete cycles of pectoral fin oscillation. The shape deformation of the pectoral fin throughout the oscillation was taken from the experimental kinematics. The pressure distribution on the body of the bird wrasse and its pectoral fins was computed and integrated to give body and fin forces which were decomposed into lift and thrust. The velocity field variation on the surface of the wrasse body, on the pectoral fins and in the near-wake was computed throughout the swimming cycle. We compared our computational results for the steady, quasi-steady and unsteady cases with the experimental data on axial and vertical acceleration obtained from the pectoral fin kinematics experiments. These comparisons show that steady state computations are incapable of describing the fluid dynamics of flapping fins. Quasi-steady state computations, with correct incorporation of the experimental kinematics, are useful when determining trends in force production, but do not provide accurate estimates of the magnitudes of the forces produced. By contrast, unsteady computations about the deforming pectoral fins using experimentally measured fin kinematics were found to give excellent agreement, both in the time history of force production throughout the flapping strokes and in the magnitudes of the generated forces.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Dejong, E. Schuyler; Deberardino, T. M.; Brooks, D. E.
Background: Pin tract infection is a common complication of external fixation. An antiinfective external fixator pin might help to reduce the incidence of pin tract infection and improve pin fixation. Methods: Stainless steel and titanium external fixator pins, with and without a lipid stabilized hydroxyapatite/chlorhexidine coating, were evaluated in a goat model. Two pins contaminated with an identifiable Staphylococcus aureus strain were inserted into each tibia of 12 goats. The pin sites were examined daily. On day 14, the animals were killed, and the pin tips cultured. Insertion and extraction torques were measured. Results: Infection developed in 100% of uncoatedmore » pins, whereas coated pins demonstrated 4.2% infected, 12.5% colonized, and the remainder, 83.3%, had no growth (p < 0.01). Pin coating decreased the percent loss of fixation torque over uncoated pins (p = 0.04). Conclusion: These results demonstrate that the lipid stabilized hydroxyapatite/chlorhexidine coating was successful in decreasing infection and improving fixation of external fixator pins.« less
Experimental parametric study of a biomimetic fish robot actuated by piezoelectric actuators
NASA Astrophysics Data System (ADS)
Wiguna, T.; Park, Hoon C.; Heo, S.; Goo, Nam S.
2007-04-01
This paper presents an experiment and parametric study of a biomimetic fish robot actuated by the Lightweight Piezocomposite Actuator (LIPCA). The biomimetic aspects in this work are the oscillating tail beat motion and shape of caudal fin. Caudal fins that resemble fins of BCF (Body and Caudal Fin) mode fish were made in order to perform parametric study concerning the effect of caudal fin characteristics on thrust production at an operating frequency range. The observed caudal fin characteristics are the shape, stiffness, area, and aspect ratio. It is found that a high aspect ratio caudal fin contributes to high swimming speed. The robotic fish propelled by artificial caudal fins shaped after thunniform-fish and mackerel caudal fins, which have relatively high aspect ratio, produced swimming speed as high as 2.364 cm/s and 2.519 cm/s, respectively, for a 300 V p-p input voltage excited at 0.9 Hz. Thrust performance of the biomimetic fish robot is examined by calculating Strouhal number, Froude number, Reynolds number, and power consumption.
NASA Astrophysics Data System (ADS)
Ostiguy, Pierre-Claude; Quaegebeur, Nicolas; Masson, Patrice
2014-03-01
In this study, a correlation-based imaging technique called "Excitelet" is used to monitor an aerospace grade aluminum plate, representative of an aircraft component. The principle is based on ultrasonic guided wave generation and sensing using three piezoceramic (PZT) transducers, and measurement of reflections induced by potential defects. The method uses a propagation model to correlate measured signals with a bank of signals and imaging is performed using a roundrobin procedure (Full-Matrix Capture). The formulation compares two models for the complex transducer dynamics: one where the shear stress at the tip of the PZT is considered to vary as a function of the frequency generated, and one where the PZT is discretized in order to consider the shear distribution under the PZT. This method allows taking into account the transducer dynamics and finite dimensions, multi-modal and dispersive characteristics of the material and complex interactions between guided wave and damages. Experimental validation has been conducted on an aerospace grade aluminum joint instrumented with three circular PZTs of 10 mm diameter. A magnet, acting as a reflector, is used in order to simulate a local reflection in the structure. It is demonstrated that the defect can be accurately detected and localized. The two models proposed are compared to the classical pin-force model, using narrow and broad-band excitations. The results demonstrate the potential of the proposed imaging techniques for damage monitoring of aerospace structures considering improved models for guided wave generation and propagation.
Iso-geometric analysis for neutron diffusion problems
DOE Office of Scientific and Technical Information (OSTI.GOV)
Hall, S. K.; Eaton, M. D.; Williams, M. M. R.
Iso-geometric analysis can be viewed as a generalisation of the finite element method. It permits the exact representation of a wider range of geometries including conic sections. This is possible due to the use of concepts employed in computer-aided design. The underlying mathematical representations from computer-aided design are used to capture both the geometry and approximate the solution. In this paper the neutron diffusion equation is solved using iso-geometric analysis. The practical advantages are highlighted by looking at the problem of a circular fuel pin in a square moderator. For this problem the finite element method requires the geometry tomore » be approximated. This leads to errors in the shape and size of the interface between the fuel and the moderator. In contrast to this iso-geometric analysis allows the interface to be represented exactly. It is found that, due to a cancellation of errors, the finite element method converges more quickly than iso-geometric analysis for this problem. A fuel pin in a vacuum was then considered as this problem is highly sensitive to the leakage across the interface. In this case iso-geometric analysis greatly outperforms the finite element method. Due to the improvement in the representation of the geometry iso-geometric analysis can outperform traditional finite element methods. It is proposed that the use of iso-geometric analysis on neutron transport problems will allow deterministic solutions to be obtained for exact geometries. Something that is only currently possible with Monte Carlo techniques. (authors)« less
NASA Astrophysics Data System (ADS)
Kim, M. H.; Duong, X. Q.; Chung, J. D.
2017-03-01
One of the drawbacks in latent thermal energy storage system is the slow charging and discharging time due to the low thermal conductivity of the phase change materials (PCM). This study numerically investigated the PCM melting process inside a finned tube to determine enhanced heat transfer performance. The influences of fin length and fin numbers were investigated. Also, two different fin orientations, a vertical and horizontal type, were examined, using two different simulation methods, constrained and unconstrained. The unconstrained simulation, which considers the density difference between the solid and liquid PCM showed approximately 40 % faster melting rate than that of constrained simulation. For a precise estimation of discharging performance, unconstrained simulation is essential. Thermal instability was found in the liquid layer below the solid PCM, which is contrary to the linear stability theory, due to the strong convection driven by heat flux from the coil wall. As the fin length increases, the area affected by the fin becomes larger, thus the discharging time becomes shorter. The discharging performance also increased as the fin number increased, but the enhancement of discharging performance by more than two fins was not discernible. The horizontal type shortened the complete melting time by approximately 10 % compared to the vertical type.
Limb lengthening in short-stature patients using monolateral and circular external fixators.
Lie, Chester W H; Chow, W
2009-08-01
To review the results of distraction osteogenesis in short-stature patients in our centre and analyse outcomes including complications. Retrospective study. University teaching hospital, Hong Kong. Eight patients with short stature (three had achondroplasia, three constitutional short stature, and two hypochondroplasia) operated on for limb lengthening using monolateral or circular external fixators between 1995 and 2006 were reviewed. The mean age at the time of surgery was 20 years (range, 9-39 years). The fixators used were either Ilizarov or Orthofix. The average gain in length per bone segment was 5.2 cm (range, 3.2-8.0 cm), and the average percentage lengthening was 21% (range, 7.9-40%). The mean time in frame was 8 months (range, 4-14 months), and the average healing index was 48 days per cm of lengthening (18-110 days per cm). Minor complications (pin tract infection and transient joint stiffness) were common, and after excluding the latter the overall complication rate was 0.6 per bone segment. In our series, limb lengthening of up to 40% of the initial length of the bone segment can be achieved without significant long-term sequelae. However, the procedures were complex and prolonged, and required a special psychological approach directed at both parents and the patients. Complications are quite common, for which patients have to be well prepared before starting the procedures.
Influence of homogeneous magnetic fields on the flow of a ferrofluid in the Taylor-Couette system.
Altmeyer, S; Hoffmann, Ch; Leschhorn, A; Lücke, M
2010-07-01
We investigate numerically the influence of a homogeneous magnetic field on a ferrofluid in the gap between two concentric, independently rotating cylinders. The full Navier-Stokes equations are solved with a combination of a finite difference method and a Galerkin method. Structure, dynamics, symmetry properties, bifurcation, and stability behavior of different vortex structures are investigated for axial and transversal magnetic fields, as well as combinations of them. We show that a transversal magnetic field modulates the Taylor vortex flow and the spiral vortex flow. Thus, a transversal magnetic field induces wavy structures: wavy Taylor vortex flow (wTVF) and wavy spiral vortex flow. In contrast to the classic wTVF, which is a secondarily bifurcating structure, these magnetically generated wavy Taylor vortices are pinned by the magnetic field, i.e., they are stationary and they appear via a primary forward bifurcation out of the basic state of circular Couette flow.
NASA Astrophysics Data System (ADS)
Guan, Dongshi; Wang, Yong Jian; Charlaix, Elisabeth; Tong, Penger
We report direct atomic-force-microscope measurements of capillary force hysteresis and relaxation of a circular moving contact line (CL) formed on a long micron-sized hydrophobic fiber intersecting a water-air interface. The measured capillary force hysteresis and CL relaxation show a strong asymmetric speed dependence in the advancing and receding directions. A unified model based on force-assisted barrier-crossing is utilized to find the underlying energy barrier Eb and size λ associated with the defects on the fiber surface. The experiment demonstrates that the pinning (relaxation) and depinning dynamics of the CL can be described by a common microscopic frame-work, and the advancing and receding CLs are influenced by two different sets of relatively wetting and non-wetting defects on the fiber surface. Work supported in part by the Research Grants Council of Hong Kong SAR.
NASA Technical Reports Server (NTRS)
Stagliano, T. R.; Spilker, R. L.; Witmer, E. A.
1976-01-01
A user-oriented computer program CIVM-JET 4B is described to predict the large-deflection elastic-plastic structural responses of fragment impacted single-layer: (a) partial-ring fragment containment or deflector structure or (b) complete-ring fragment containment structure. These two types of structures may be either free or supported in various ways. Supports accommodated include: (1) point supports such as pinned-fixed, ideally-clamped, or supported by a structural branch simulating mounting-bracket structure and (2) elastic foundation support distributed over selected regions of the structure. The initial geometry of each partial or complete ring may be circular or arbitrarily curved; uniform or variable thicknesses of the structure are accommodated. The structural material is assumed to be initially isotropic; strain hardening and strain rate effects are taken into account.
Gas turbine vane platform element
Campbell, Christian X [Oviedo, FL; Schiavo, Anthony L [Oviedo, FL; Morrison, Jay A [Oviedo, FL
2012-08-28
A gas turbine CMC shroud plate (48A) with a vane-receiving opening (79) that matches a cross-section profile of a turbine vane airfoil (22). The shroud plate (48A) has first and second curved circumferential sides (73A, 74A) that generally follow the curves of respective first and second curved sides (81, 82) of the vane-receiving opening. Walls (75A, 76A, 77A, 78A, 80, 88) extend perpendicularly from the shroud plate forming a cross-bracing structure for the shroud plate. A vane (22) may be attached to the shroud plate by pins (83) or by hoop-tension rings (106) that clamp tabs (103) of the shroud plate against bosses (105) of the vane. A circular array (20) of shroud plates (48A) may be assembled to form a vane shroud ring in which adjacent shroud plates are separated by compressible ceramic seals (93).
A Joined-Wing Flight Experiment
2008-02-01
and fuselage, reference geometry and ventral fins, reference geometry and winglets and finally reference geometry and main gear strut-fins. He...the addition of winglets or strut fins, unless the center of mass was shifted forward [30]. Throughout his analysis it became clear that VA-1...With the addition of winglets or fins placed over the main wheel struts, 02.0≈Δ βN C . The addition of the winglets or strut fins introduces a spiral
Liang, Lihua; Sun, Mingxiao; Shi, Hongyu; Luan, Tiantian
2017-01-01
Fin-angle feedback control is usually used in conventional fin stabilizers, and its actual anti-rolling effect is difficult to reach theoretical design requirements. Primarily, lift of control torque is a theoretical value calculated by static hydrodynamic characteristics of fin. However, hydrodynamic characteristics of fin are dynamic while fin is moving in waves. As a result, there is a large deviation between actual value and theoretical value of lift. Firstly, the reasons of deviation are analyzed theoretically, which could avoid a variety of interference factors and complex theoretical derivations. Secondly, a new device is designed for direct measurement of actual lift, which is composed of fin-shaft combined mechanism and sensors. This new device can make fin-shaft not only be the basic function of rotating fin, but also detect actual lift. Through analysis using stiffness matrix of Euler-Bernoulli beam, displacement of shaft-core end is measured instead of lift which is difficult to measure. Then quantitative relationship between lift and displacement is defined. Three main factors are analyzed with quantitative relationship. What is more, two installation modes of sensors and a removable shaft-end cover are proposed according to hydrodynamic characteristics of fin. Thus the new device contributes to maintenance and measurement. Lastly, the effectiveness and accuracy of device are verified by contrasting calculation and simulation on the basis of actual design parameters. And the new measuring lift method can be proved to be effective through experiments. The new device is achieved from conventional fin stabilizers. Accordingly, the reliability of original equipment is inherited. The alteration of fin stabilizers is minor, which is suitable for engineering application. In addition, the flexural properties of fin-shaft are digitized with analysis of stiffness matrix. This method provides theoretical support for engineering application by carrying out finite element analysis with computers. PMID:28046122
Assessment of Thermal Performance of Functionally Graded Materials in Longitudinal Fins
NASA Astrophysics Data System (ADS)
Hassanzadeh, R.; Bilgili, M.
2018-01-01
Assessment of the thermal characteristics of materials in heat exchangers with longitudinal fins is performed in the case where a conventional homogeneous material of a longitudinal fin is replaced by a functionally graded one, in which the fin material properties, such as the conductivity, are assumed to be graded as linear and power-law functions along the normal axis from the fin base to the fin tip. The resulting equations are calculated under two (Dirichlet and Neumann) boundary conditions. The equations are solved by an approximate analytical method with the use of the mean value theorem. The results show that the inhomogeneity index of a functionally graded material plays an important role for the thermal energy characteristics in such heat exchangers. In addition, it is observed that the use of such a material in longitudinal fins enhances the rate of heat transfer between the fin surface and surrounding fluid. Hopefully, the results obtained in the study will arouse interest of designers in heat exchange industry.
Discovery of novel selenium derivatives as Pin1 inhibitors by high-throughput screening
DOE Office of Scientific and Technical Information (OSTI.GOV)
Subedi, Amit; Graduate School of Science and Engineering, Saitama University, Saitama, 338-8570; Shimizu, Takeshi
2016-06-03
Peptidyl prolyl cis/trans isomerization by Pin1 regulates various oncogenic signals during cancer progression, and its inhibition through multiple approaches has established Pin1 as a therapeutic target. However, lack of simplified screening systems has limited the discovery of potent Pin1 inhibitors. We utilized phosphorylation-dependent binding of Pin1 to its specific substrate to develop a screening system for Pin1 inhibitors. Using this system, we screened a chemical library, and identified a novel selenium derivative as Pin1 inhibitor. Based on structure-activity guided chemical synthesis, we developed more potent Pin1 inhibitors that inhibited cancer cell proliferation. -- Highlights: •Novel screening for Pin1 inhibitors basedmore » on Pin1 binding is developed. •A novel selenium compound is discovered as Pin1 inhibitor. •Activity guided chemical synthesis of selenium derivatives resulted potent Pin1 inhibitors.« less
Study of Swept Angle Effects on Grid Fins Aerodynamics Performance
NASA Astrophysics Data System (ADS)
Faza, G. A.; Fadillah, H.; Silitonga, F. Y.; Agoes Moelyadi, Mochamad
2018-04-01
Grid fin is an aerodynamic control surface that usually used on missiles and rockets. In the recent several years many researches have conducted to develop a more efficient grid fins. There are many possibilities of geometric combination could be done to improve aerodynamics characteristic of a grid fin. This paper will only discuss about the aerodynamics characteristics of grid fins compared by another grid fins with different swept angle. The methodology that used to compare the aerodynamics is Computational Fluid Dynamics (CFD). The result of this paper might be used for future studies to answer our former question or as a reference for related studies.
Investigation of internally finned LED heat sinks
NASA Astrophysics Data System (ADS)
Li, Bin; Xiong, Lun; Lai, Chuan; Tang, Yumei
2018-03-01
A novel heat sink is proposed, which is composed of a perforated cylinder and internally arranged fins. Numerical studies are performed on the natural convection heat transfer from internally finned heat sinks; experimental studies are carried out to validate the numerical results. To compare the thermal performances of internally finned heat sinks and externally finned heat sinks, the effects of the overall diameter, overall height, and installation direction on maximum temperature, air flow and heat transfer coefficient are investigated. The results demonstrate that internally finned heat sinks show better thermal performance than externally finned heat sinks; the maximum temperature of internally finned heat sinks decreases by up to 20% compared with the externally finned heat sinks. The existence of a perforated cylinder and the installation direction of the heat sink affect the thermal performance significantly; it is shown that the heat transfer coefficient of the heat sink with the perforated cylinder is improved greater than that with the imperforated cylinder by up to 34%, while reducing the mass of the heat sink by up to 13%. Project supported by the Scientific Research Fund of Sichuan Provincial Education Department (No. 18ZB0516) and the Sichuan University of Arts and Science (No. 2016KZ009Y).
Simon, Malene; Stafford, Kathleen M; Beedholm, Kristian; Lee, Craig M; Madsen, Peter T
2010-11-01
Most baleen whales undertake migrations between low-latitude breeding grounds and high-latitude feeding grounds. Though little is known about the timing of their migration from the Arctic, fin whales are assumed to undertake a similar migratory pattern. To address questions about habitat use and migrations, the acoustic activity of fin whales in Davis Strait, between Greenland and Canada, was monitored continuously for two years using three bottom-moored acoustic recorders. The acoustic power in the fin whale call frequencies peaked in November-December, showing that fin whales are present in Davis Strait much later in the year than previously expected. The closely timed peaks in song activity and conception time imply that not all fin whales migrate south to mate, but rather start mating at high latitudes rather than or before migrating. Singing activity was strongly linked to daylight hours, suggesting that fin whales might feed during the few daylight hours of the late fall and early Arctic winter. A negative correlation between the advancing sea ice front and power in fin whale frequencies indicates that future changes in sea ice conditions from global warming might change the distribution and migratory patterns of fin whales near the poles.
The origin of a new fin skeleton through tinkering
Stewart, Thomas A.
2015-01-01
Adipose fins are positioned between the dorsal and caudal fins of many teleost fishes and primitively lack skeleton. In at least four lineages, adipose fins have evolved lepidotrichia (bony fin rays), co-opting the developmental programme for the dermal skeleton of other fins into this new territory. Here I provide, to my knowledge, the first description of lepidotrichia development in an adipose fin, characterizing the ontogeny of the redtail catfish, Phractocephalus hemioliopterus. Development of these fin rays differs from canonical lepidotrich development in the following four ways: skeleton begins developing in adults, not in larvae; rays begin developing at the fin's distal tip, not proximally; the order in which rays ossify is variable, not fixed; and lepidotrichia appear to grow both proximally and distally, not exclusively proximodistally. Lepidotrichia are often wavy, of irregular thickness and exhibit no regular pattern of segmentation or branching. This skeleton is among the most variable observed in a vertebrate appendage, offering a unique opportunity to explore the basis of hypervariation, which is generally assumed to reflect an absence of function. I argue that this variation reflects a lack of canalization as compared with other, more ancient lepidotrichs and suggest developmental context can affect the morphology of serial homologues. PMID:26179803
The evolutionary history of the development of the pelvic fin/hindlimb
Don, Emily K; Currie, Peter D; Cole, Nicholas J
2013-01-01
The arms and legs of man are evolutionarily derived from the paired fins of primitive jawed fish. Few evolutionary changes have attracted as much attention as the origin of tetrapod limbs from the paired fins of ancestral fish. The hindlimbs of tetrapods are derived from the pelvic fins of ancestral fish. These evolutionary origins can be seen in the examination of shared gene and protein expression patterns during the development of pelvic fins and tetrapod hindlimbs. The pelvic fins of fish express key limb positioning, limb bud induction and limb outgrowth genes in a similar manner to that seen in hindlimb development of higher vertebrates. We are now at a point where many of the key players in the development of pelvic fins and vertebrate hindlimbs have been identified and we can now readily examine and compare mechanisms between species. This is yielding fascinating insights into how the developmental programme has altered during evolution and how that relates to anatomical change. The role of pelvic fins has also drastically changed over evolutionary history, from playing a minor role during swimming to developing into robust weight-bearing limbs. In addition, the pelvic fins/hindlimbs have been lost repeatedly in diverse species over evolutionary time. Here we review the evolution of pelvic fins and hindlimbs within the context of the changes in anatomical structure and the molecular mechanisms involved. PMID:22913749
NASA Astrophysics Data System (ADS)
Zeitlin, Bruce A.; Gregory, Eric; Pyon, Taeyoung; Scanlan, R. M.; Polyanskii, Anatolii A.; Lee, Peter J.
2004-06-01
A number of configurations of a mono element internal tin conductor (MEIT) were fabricated to explore the effect of internal fins on the effective filament size (Deff) and its effect on wire processing. A current density of 2.85 × 109 A/m2 (12 T) was achieved in a high tin, high Nb conductor. Wire lengths as long as 15.8 km at 0.254 mm diameter with breaks averaging 3 per unit length were achieved. Magnetization measurements and Magneto-Optical (MO) images were taken of the finned and non-fin conductor which indicated the fins appeared to be effective. The Deff achieved in the fin conductor was 80 μm compared with an equivalent conductor without a fin of 165 μm.
NASA Astrophysics Data System (ADS)
Wang, H. S.; Honda, Hiroshi
A theoretical study has been made on the effects of tube diameter and tubeside fin geometry on the heat transfer performance of air-cooled condensers. Extensive numerical calculations of overall heat transfer from refrigerant R410A flowing inside a horizontal microfin tube to ambient air were conducted for a typical operating condition of the air-cooled condenser. The tubeside heat transfer coefficient was calculated by applying a modified stratified flow model developed by Wang et al.8). The numerical results show that the effects of tube diameter, fin height, fin number and helix angle of groove are significant, whereas those of the width of flat portion at the fin tip, the radius of round corner at the fin tip and the fin half tip angle are small.
NASA Astrophysics Data System (ADS)
Peng, Y.; Zhang, S. J.; Shen, F.; Wang, X. B.; Yang, X. R.; Yang, L. J.
2017-11-01
The air-cooled heat exchanger plays an important role in the field of industry like for example in thermal power plants. On the other hand, it can be used to remove core decay heat out of containment passively in case of a severe accident circumstance. Thus, research on the performance of fins in air-cooled heat exchangers can benefit the optimal design and operation of cooling systems in nuclear power plants. In this study, a CFD (Computational Fluid Dynamic) method is implemented to investigate the effects of inlet velocity, fin spacing and tube pitch on the flow and the heat transfer characteristics of flat fins constructed of various materials (316L stainless steel, copper-nickel alloy and aluminium). A three dimensional geometric model of flat finned tube bundles with fixed longitudinal tube pitch and transverse tube pitch is established. Results for the variation of the average convective heat transfer coefficient with respect to cooling air inlet velocity, fin spacing, tube pitch and fin material are obtained, as well as for the pressure drop of the cooling air passing through finned tube. It is shown that the increase of cooling air inlet velocity results in enhanced average convective heat transfer coefficient and decreasing pressure drop. Both fin spacing and tube pitch engender positive effects on pressure drop and have negative effects on heat transfer characteristics. Concerning the fin material, the heat transfer performance of copper-nickel alloy is superior to 316L stainless steel and inferior to aluminium.
Hisar, Olcay; Sönmez, Adem Yavuz; Hisar, Şükriye Aras; Budak, Harun; Gültepe, Nejdet
2013-04-01
An investigation has been described on the relationship of body length, age and sex with adipose fin length and the number of androgen receptor (AR)-containing cells in the adipose fin as a secondary sexual characteristic for brown trout (Salmo trutta fario). Firstly, body and adipose fin lengths of 2- to 5-year-old brown trout were measured. Thereafter, these fish were killed by decapitation, then their sexes were determined, and adipose fins were excised. The cellular bases of AR binding activities in the adipose fins were analyzed with an antibody against human/rat AR peptide. Immunocytochemistry and western blotting techniques were performed with this antibody. Analysis of morphological measurements indicated that body length and age had a linear relationship with adipose fin length. The coefficients of determination for the body length and age were 0.92 and 0.85 in the male fish and 0.76 and 0.73 in the female fish against the adipose fin length, respectively. At 2 years of age, cells in the adipose fin did not exhibit AR immunoreactivity. However, AR-immunopositive cells were abundant in the adipose fin of 3- to 5-year-old fish. Moreover, the number of AR-immunopositive cells was significantly (P < 0.05) high in males and increased with age. These observations indicate that the adipose fin in the brown trout is a probable target for androgen action and that tissue function or development may to some extent be androgen dependent. In addition, it is likely that such an effect will be mediated by specific androgen receptors.
50 CFR 600.1200 - Purpose and scope.
Code of Federal Regulations, 2010 CFR
2010-10-01
... ADMINISTRATION, DEPARTMENT OF COMMERCE MAGNUSON-STEVENS ACT PROVISIONS Shark Finning § 600.1200 Purpose and scope. The regulations in this subpart govern “shark finning” (the removal of shark fins and discarding of the carcass), the possession of shark fins, and the landing into U.S. ports of shark fins without...
50 CFR 600.1202 - Definitions.
Code of Federal Regulations, 2013 CFR
2013-10-01
..., DEPARTMENT OF COMMERCE MAGNUSON-STEVENS ACT PROVISIONS Shark Finning § 600.1202 Definitions. (a) In addition... at a dock, berth, beach, seawall, or ramp to begin offloading fish. Shark finning means taking a shark, removing a fin or fins (whether or not including the tail), and returning the remainder of the...
50 CFR 600.1200 - Purpose and scope.
Code of Federal Regulations, 2012 CFR
2012-10-01
... ADMINISTRATION, DEPARTMENT OF COMMERCE MAGNUSON-STEVENS ACT PROVISIONS Shark Finning § 600.1200 Purpose and scope. The regulations in this subpart govern “shark finning” (the removal of shark fins and discarding of the carcass), the possession of shark fins, and the landing into U.S. ports of shark fins without...
50 CFR 600.1200 - Purpose and scope.
Code of Federal Regulations, 2014 CFR
2014-10-01
... ADMINISTRATION, DEPARTMENT OF COMMERCE MAGNUSON-STEVENS ACT PROVISIONS Shark Finning § 600.1200 Purpose and scope. The regulations in this subpart govern “shark finning” (the removal of shark fins and discarding of the carcass), the possession of shark fins, and the landing into U.S. ports of shark fins without...
50 CFR 600.1202 - Definitions.
Code of Federal Regulations, 2012 CFR
2012-10-01
..., DEPARTMENT OF COMMERCE MAGNUSON-STEVENS ACT PROVISIONS Shark Finning § 600.1202 Definitions. (a) In addition... at a dock, berth, beach, seawall, or ramp to begin offloading fish. Shark finning means taking a shark, removing a fin or fins (whether or not including the tail), and returning the remainder of the...
50 CFR 600.1200 - Purpose and scope.
Code of Federal Regulations, 2011 CFR
2011-10-01
... ADMINISTRATION, DEPARTMENT OF COMMERCE MAGNUSON-STEVENS ACT PROVISIONS Shark Finning § 600.1200 Purpose and scope. The regulations in this subpart govern “shark finning” (the removal of shark fins and discarding of the carcass), the possession of shark fins, and the landing into U.S. ports of shark fins without...
50 CFR 600.1200 - Purpose and scope.
Code of Federal Regulations, 2013 CFR
2013-10-01
... ADMINISTRATION, DEPARTMENT OF COMMERCE MAGNUSON-STEVENS ACT PROVISIONS Shark Finning § 600.1200 Purpose and scope. The regulations in this subpart govern “shark finning” (the removal of shark fins and discarding of the carcass), the possession of shark fins, and the landing into U.S. ports of shark fins without...
50 CFR 600.1202 - Definitions.
Code of Federal Regulations, 2014 CFR
2014-10-01
..., DEPARTMENT OF COMMERCE MAGNUSON-STEVENS ACT PROVISIONS Shark Finning § 600.1202 Definitions. (a) In addition... at a dock, berth, beach, seawall, or ramp to begin offloading fish. Shark finning means taking a shark, removing a fin or fins (whether or not including the tail), and returning the remainder of the...
Note: Dynamic analysis of a robotic fish motion with a caudal fin with vertical phase differences
NASA Astrophysics Data System (ADS)
Yun, Dongwon; Kim, Kyung-Soo; Kim, Soohyun; Kyung, Jinho; Lee, Sunghwi
2013-03-01
In this paper, a robotic fish with a caudal fin with vertical phase differences is studied, especially focusing on the energy consumption. Energies for thrusting a conventional robotic fish and one with caudal fin with vertical phase differences are obtained and compared each other. It is shown that a robotic fish with a caudal fin with vertical phase differences can save more energy, which implies the efficient thrusting via a vertically waving caudal fin.
Self-locking double retention redundant pull pin release
NASA Technical Reports Server (NTRS)
Killgrove, Thomas O. (Inventor)
1987-01-01
A double-retention redundant pull pin release system is disclosed. The system responds to a single pull during an intentional release operation. A spiral-threaded main pin is seated in a mating bore in a housing, which main pin has a flange fastened thereon at the part of the main pin which is exterior to the housing. Accidental release tends to rotate the main pin. A secondary pin passes through a slightly oversized opening in the flange and is seated in a second bore in the housing. The pins counteract against one another to prevent accidental release. A frictional lock is shared between the main and secondary pins to enhance further locking of the system. The secondary pin, in response to a first pull, is fully retracted from its bore and flange hole. Thereafter the pull causes the main pin to rotate free of the housing to release, for example, a parachute mechanism.
Analytical study on the thermal performance of a partially wet constructal T-shaped fin
NASA Astrophysics Data System (ADS)
Hazarika, Saheera Azmi; Zeeshan, Mohd; Bhanja, Dipankar; Nath, Sujit
2017-07-01
The present paper addresses the thermal analysis of a T-shaped fin under partially wet condition by adopting a cubic variation of the humidity ratio of saturated air with the corresponding fin surface temperature. The point separating the dry and wet parts may lie either in the flange or stem part of the fin and so, two different cases having different governing equations and boundary conditions are analyzed in this paper. Since the governing equations are highly non-linear, they are solved by using an analytical technique called the Differential Transform Method and subsequently, the dry fin length, temperature distribution and fin performances are evaluated and analyzed for a wide range of the various psychometric, geometric and thermo-physical parameters. Finally, it can be highlighted that relative humidity has a pronounced effect on the performance parameters when the fin surface is partially wet whereas this effect is marginally small for fully wet surface.
NASA Astrophysics Data System (ADS)
Ko, Dong Guk; Cong Ge, Jun; Im, Ik Tae; Choi, Nag Jung; Kim, Min Soo
2018-01-01
In this study, we analyzed the heat dissipation performance of UCD lamp ballast fin with various aspect ratios. The minimum grid size was 0.02 mm and the number of grid was approximately 11,000. In order to determine the influence of the aspect ratio on the heat dissipation performance of UCD lamp ballast fin, the heat transfer area of the fin was kept constant at 4 mm2. The aspect ratios of the fin were 2 mm: 2 mm (basic model), 1.5 mm: 2.7 mm and 2.7 mm: 1.5 mm, respectively. The heat flux and heat flux time at fin were kept constant at 1×105 W/m2 and 10 seconds, respectively. The heat dissipation performance by the fin was the best at an aspect ratio of 1.5 mm: 2.7 mm.
Finned Tube With Vortex Generators For A Heat Exchanger.
Sohal, Manohar S.; O'Brien, James E.
2005-12-20
A system for and method of manufacturing a finned tube for a heat exchanger is disclosed herein. A continuous fin strip is provided with at one pair of vortex generators. A tube is rotated and linearly displaced while the continuous fin strip with vortex generators is spirally wrapped around the tube.
Finned Tube With Vortex Generators For A Heat Exchanger.
Sohal, Monohar S.; O'Brien, James E.
2004-09-14
A system for and method of manufacturing a finned tube for a heat exchanger is disclosed herein. A continuous fin strip is provided with at least one pair of vortex generators. A tube is rotated and linearly displaced while the continuous fin strip with vortex generators is spirally wrapped around the tube.
A shift in anterior–posterior positional information underlies the fin-to-limb evolution
Onimaru, Koh; Kuraku, Shigehiro; Takagi, Wataru; Hyodo, Susumu; Sharpe, James; Tanaka, Mikiko
2015-01-01
The pectoral fins of ancestral fishes had multiple proximal elements connected to their pectoral girdles. During the fin-to-limb transition, anterior proximal elements were lost and only the most posterior one remained as the humerus. Thus, we hypothesised that an evolutionary alteration occurred in the anterior–posterior (AP) patterning system of limb buds. In this study, we examined the pectoral fin development of catshark (Scyliorhinus canicula) and revealed that the AP positional values in fin buds are shifted more posteriorly than mouse limb buds. Furthermore, examination of Gli3 function and regulation shows that catshark fins lack a specific AP patterning mechanism, which restricts its expression to an anterior domain in tetrapods. Finally, experimental perturbation of AP patterning in catshark fin buds results in an expansion of posterior values and loss of anterior skeletal elements. Together, these results suggest that a key genetic event of the fin-to-limb transformation was alteration of the AP patterning network. DOI: http://dx.doi.org/10.7554/eLife.07048.001 PMID:26283004
NASA Technical Reports Server (NTRS)
Jackson, Charles M., Jr.; Harris, Roy V., Jr.
1960-01-01
An investigation has been made in the Langley 4- by 4-foot supersonic pressure tunnel at a Mach number of 1.99 to determine the longitudinal stability and control characteristics of a reentry model consisting of a lenticular-shaped body with two fin configurations (horizontal fins with end plates). Effects of deflecting the larger size fins as pitch-control surfaces were also investigated. The results indicate that the body alone was unstable from an angle of attack of 0 deg to about 55 deg where it became stable and remained so to 90 deg. The addition of fins provided positive longitudinal stability throughout the angle-of-attack range and increased the lift-drag ratio of the configuration. Reducing the horizontal-fin area at the inboard trailing edge of the fin had only a small effect on the aerodynamic characteristics of the vehicle for the condition of no fin deflection. Deflecting the fins, appeared to be an effective means of pitch control and had only a small effect on lift-drag ratio.
NASA Astrophysics Data System (ADS)
Wang, Hongjuan; Han, Genquan; Jiang, Xiangwei; Liu, Yan; Zhang, Chunfu; Zhang, Jincheng; Hao, Yue
2017-04-01
In this work, the boosting effect on the performance of GeSn n-channel fin tunneling FET (nFinTFET) enabled by uniaxial tensile stress is investigated theoretically. As the fin rotates within the (001) plane, the uniaxial tensile stress is always along its direction. The electrical characteristics of tensile-stressed GeSn nFinTFETs with point and line tunneling modes are computed utilizing the technology computer aided design (TCAD) simulator in which the dynamic nonlocal band-to-band tunneling (BTBT) algorithm is employed. In comparison with the relaxed devices, tensile-stressed GeSn nFinTFETs achieve a substantial enhancement in band-to-band tunneling generation rate (G BTBT) and on-state current I ON owing to the reduced bandgap E G induced by the tensile stress. Performance improvement of GeSn nFinTFETs induced by tensile stress demonstrates a strong dependence on channel direction and tunneling modes. Under the same magnitude of stress, line-nFinTFETs obtain a more pronounced I ON enhancement over the transistors with point tunneling mode.
Analog and RF performance of a multigate FinFET at nano scale
NASA Astrophysics Data System (ADS)
Kumar, Abhishek
2016-12-01
In this paper, analog and RF performance of the Fin field effect transistor (FET) at Nano scale is observed through 3D simulation. FinFET devices like rectangular gate all around (RE-GAA) FinFET, cylindrical gate all around (CY-GAA) FinFET and triple gate (TG) FinFET are observed. The figure of merit (FOMs) such as input-output characteristics, trans-conductance (gm), output-conductance (gd), intrinsic gain (gm/gd), gate capacitance (gate to source and total gate capacitance), unity gain cut-off frequency (ft), trans-conductance generation factor (TGF), gain frequency product (GFP), gain bandwidth product (GBP) and gain transconductance frequency product (GTFP) are observed. The analog performance of a FinFETs are observed by realising source follower circuit with NMOS transistor as a current source. The source follower circuit gain is observed. It has been observed that maximum capacitance is observed in case gate all around condition. Rectangular gate all around has the highest transconductance. In the source follower circuit, the gain curve (Vout/Vin) is sharper for TG-FinFET.
Aerothermoelastic Analysis of a NASP-Like Vertical Fin
NASA Technical Reports Server (NTRS)
Rodgers, John P.
1992-01-01
Several aeroelastic stability analyses for a vertical fin similar to that of the National Aero-Space Plane are described. The objectives of the study were to design and obtain an experimental data base for a supersonic wind-tunnel model of the fin in order to examine the effects of thermal loading on the flutter characteristics. This paper describes the preliminary efforts to design the wind-tunnel model, including several of the geometric parameter variations that were analyzed. The dominant flutter mechanism involved a flap vibration mode and a fin bending mode. Variation of the thicknesses of flap and root flexures, used to attach the flap to the fin, and the fin to a support, significantly affected the flutter boundary. Uniform thermal loads, affecting only material properties, had little effect, as did the application of different uniform temperatures to each side of the fin. In contrast, the application of significant chord-wise thermal gradients induced stresses which reduced the flutter dynamic pressure by as much as 37 percent. For less extreme distributed loading, the low-aspect ratio fin was relatively unaffected.
Gillies, Eric A; Bondarenko, Volodymyr; Cosson, Jacky; Pacey, Allan A
2013-02-01
The flagella of sturgeon sperm have an ultrastructure comprising paddle-like fins extending along most of their length. These fins are seen in several other marine and freshwater fish. The sperm of these fish are fast swimmers and are relatively short lived: it is therefore tempting to think of these fins as having evolved for hydrodynamic advantage, but the actual advantage they impart, at such a small length scale and slow speed, is unclear. The phrase "the fins improve hydrodynamic efficiency" is commonly found in biological literature, yet little hydrodynamic analysis has previously been used to support such conjectures. In this paper, we examine various hydrodynamic models of sturgeon sperm and investigate both swimming velocity and energy expenditure. All of the models indicate a modest hydrodynamic advantage of finned sperm, in both straight line swimming speed and a hydrodynamic efficiency measure. We find a hydrodynamic advantage for a flagellum with fins, over one without fins, of the order of 15-20% in straight line propulsive velocity and 10-15% in a hydrodynamic efficiency measure. Copyright © 2012 Wiley Periodicals, Inc.
Establishing the need for an engineering standard for agricultural hitch pins.
Deboy, G R; Knapp, W M; Field, W E; Krutz, G W; Corum, C L
2012-04-01
Documented incidents have occurred in which failure or unintentional disengagement of agricultural hitch pins has contributed to property damage and personal injury. An examination of current hitch pin use on a convenience sample of farm operations in Indiana revealed a variety of non-standard, worn and damaged, and inappropriately sized hitch pins in use. Informal interviews with the farm operators confirmed that hitch pin misuse, failure, or disengagement is a relatively widespread problem that remains largely unaddressed. On-site observations also suggested a low use of hitch pin retaining devices or safety chains. A review of prior research revealed that little attention has been given to this problem, and currently no documentation allows for an estimate of the frequency or severity of losses associated with hitch pin misuse, failure, or disengagement. No specific engineering standards were found that directly applied to the design, appropriate selection, or loading capacity of agricultural hitch pins. Major suppliers of replacement hitch pins currently provide little or no information on matching hitch pin size to intended applications, and most replacement hitch pins examined were of foreign origin, with the overwhelming majority imported from China or India. These replacement hitch pins provided no specifications other than diameter, length, and, in some cases, labeling that indicated that the pins had been "heat treated. " Testing of a sample of 11 commercially available replacement hitch pins found variation along the length of the pin shaft and between individual pins in surface hardness, a potential predictor of pin failure. Examination of 17 commercially available replacement pins also revealed a variety of identifiers used to describe pin composition and fabrication methods, e.g., "heat treated." None of the pins examined provided any specifications on loading capacity. It was therefore concluded that there is a need to develop an agricultural hitch pin engineering standard that would reflect current agricultural applications and practices and that would be promoted to both original equipment manufacturers and manufacturers and suppliers of replacement hitch pins. The standard should address the design of composite pins, heat treating, surface hardening, loading capacity and labeling of such, incorporation of unintentional disengagement prevention devices, indicators of the need for replacement due to wear, and safety information that should be included in operator instructions. ASABE is the most appropriate organization to develop such a standard. It was also concluded that agricultural safety and health programs and professionals need to raise the awareness of farmers concerning the appropriate selection and use of agricultural hitch pins, including the need to replace non-standard pins with pins less likely to fail or disengage during use, the need to replace hitch pins with indications of potential failure, and the importance of using appropriate safety chains, especially during transport of equipment behind tractors and trucks on public roads.
NASA Astrophysics Data System (ADS)
Guo, Yonghong; Du, Xiaoze; Yang, Lijun
2018-02-01
Air-cooled condenser is the main equipment of the direct dry cooling system in a power plant, which rejects heat of the exhaust steam with the finned tube bundles. Therefore, the thermo-flow performances of the finned tubes have an important effect on the optimal operation of the direct dry cooling system. In this paper, the flow and heat transfer characteristics of the single row finned tubes with the conventional flat fins and novel jagged fins are investigated by numerical method. The flow and temperature fields of cooling air for the finned tubes are obtained. Moreover, the variations of the flow resistance and average convection heat transfer coefficient under different frontal velocity of air and jag number are presented. Finally, the correlating equations of the friction factor and Nusselt number versus the Reynolds number are fitted. The results show that with increasing the frontal velocity of air, the heat transfer performances of the finned tubes are enhanced but the pressure drop will increase accordingly, resulting in the average convection heat transfer coefficient and friction factor increasing. Meanwhile, with increasing the number of fin jag, the heat transfer performance is intensified. The present studies provide a reference in optimal designing for the air-cooled condenser of direct air cooling system.
Performance Analysis of a Self-Propelling Flat Plate Fin with Joint Compliance
NASA Astrophysics Data System (ADS)
Reddy, N. Srinivasa; Sen, Soumen; Pal, Sumit; Shome, Sankar Nath
2017-12-01
Fish fin muscles are compliant and they regulate the stiffness to suit different swimming conditions. This article attempts to understand the significance of presence of compliance in fin muscle with help of a flexible joint flat plate fin model. Blade element method is employed to model hydrodynamics and to compute the forces of interaction during motion of the plate within fluid. The dynamic model of self-propelling fin is developed through multi-body dynamics approach considering the hydrodynamic forces as external forces acting on the fin. The derived hydrodynamic model is validated with experiments on rigid flat plate fin. The effect of the joint stiffness and flapping frequency on the propulsion speed and efficiency is investigated through simulations using the derived and validated model. The propulsion efficiency is found to be highly influenced by the joint stiffness at a given flapping frequency. The fin attained maximum propulsion efficiency when the joint stiffness is tuned to a value at which flapping frequency matches near natural frequency of the fin. At this tuned joint stiffness and flapping frequency, the resulted Strouhal numbers are observed to fall within the optimum range (0.2 to 0.4) for maximized propulsion efficiency of flying birds and swimming aquatic animals reported in literature.
NASA Astrophysics Data System (ADS)
Kuwahara, Ken; Higashiiu, Shinya; Ito, Daisuke; Koyama, Shigeru
This paper deals with the experimental study on cooling heat transfer of supercritical carbon dioxide inside micro-fin tubes. The geometrical parameters in micro-fin tubes used in the present study are 6.02 mm in outer diameter, 4.76 mm to 5.11 mm in average inner diameter, 0.15 mm to 0.24 mm in fin height, 5 to 25 in helix angle, 46 to 52 in number of fins and 1.4 to 2.3 in area expansion ratio. Heat transfer coefficients were measured at 8-10 MPa in pressure, 360-690 kg/(m2•s) in mass velocity and 20-75 °C in CO2 temperature. The measured heat transfer coefficients of micro-fin tubes were 1.4 to 2 times higher than those of the smooth tube having 4.42 in inner diameter. The predicted heat transfer coefficients using the correlation equation, which was developed for single-phase turbulent fluid flow inside micro-fin-tubes, showed large deviations to the measured values. The new correlation to predict cooling heat transfer coefficient of supercritical carbon dioxide inside micro-fin tubes was developed taking into account the shape of fins based on experimental data empirically. This correlation equation agreed within ±20% of almost all of the experimental data.
Pin-Retraction Mechanism On Quick-Release Cover
NASA Technical Reports Server (NTRS)
Macmartin, Malcolm
1994-01-01
Quick-release cover includes pin-retraction mechanism releasing cover quickly from lower of two sets of pin connections holding cover. Cover released at top by pulling lever as described in "Lever-Arm Pin Puller" (NPO-18788). Removal of cover begins when technician or robot pulls upper-pin-release lever. Cover swings downward until tabs on lower pins are pulled through slots in their receptacles. Lower pins are then free.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Gordienko, P. V., E-mail: gorpavel@vver.kiae.ru; Kotsarev, A. V.; Lizorkin, M. P.
2014-12-15
The procedure of recovery of pin-by-pin energy-release fields for the BIPR-8 code and the algorithm of the BIPR-8 code which is used in nodal computation of the reactor core and on which the recovery of pin-by-pin fields of energy release is based are briefly described. The description and results of the verification using the module of recovery of pin-by-pin energy-release fields and the TVS-M program are given.
Electrical Connector Mechanical Seating Sensor
NASA Technical Reports Server (NTRS)
Arens, Ellen; Captain, Janine; Youngquist, Robert
2011-01-01
A sensor provides a measurement of the degree of seating of an electrical connector. This sensor provides a number of discrete distances that a plug is inserted into a socket or receptacle. The number of measurements is equal to the number of pins available in the connector for sensing. On at least two occasions, the Shuttle Program has suffered serious time delays and incurred excessive costs simply because a plug was not seated well within a receptacle. Two methods were designed to address this problem: (1) the resistive pin technique and (2) the discrete length pins technique. In the resistive pin approach, a standard pin in a male connector is replaced with a pin that has a uniform resistivity along its length. This provides a variable resistance on that pin that is dependent on how far the pin is inserted into a socket. This is essentially a linear potentiometer. The discrete approach uses a pin (or a few pins) in the connector as a displacement indicator by truncating the pin length so it sits shorter in the connector than the other pins. A loss of signal on this pin would indicate a discrete amount of displacement of the connector. This approach would only give discrete values of connector displacement, and at least one pin would be needed for each displacement value that would be of interest.
Ganser, Antonia; Thompson, Rosemary E; Tami, Ivan; Neuhoff, Dirk; Steiner, Adrian; Ito, Keita
2007-02-01
To compare the clinical benefits of stainless steel (SS) to titanium (Ti) on reducing pin track irritation/infection and pin loosening during external fracture fixation. A tibial gap osteotomy was created in 17 sheep and stabilized with four Schanz screws of either SS or Ti and an external fixation frame. Over the 12 week observation period, pin loosening was assessed by grading the radiolucency around the pins and measuring the extraction torque on pin removal at sacrifice. Irritation/infection was assessed with weekly clinical pin track grading. A histological analysis of the tissue adjacent to the pin site was made to assess biocompatibility. A statistically non-significant trend for less bone resorption around Ti pins was found during the early observation period. However, at sacrifice, there was no difference between the two materials. Also, there was no difference in the extraction torque, and there was similar remodeling and apposition of the bone around the pins. A statistically non-significant trend for more infection about SS pins at sacrifice was found. Histology showed a slightly higher prevalence of reactionary cells in SS samples, but was otherwise not much different than around Ti pins. There is no clinically relevant substantial advantage in using either SS or Ti pins on reducing pin loosening or pin track irritation/infection.
System for Controlling the Stirring Pin of a Friction Stir Welding Apparatus
NASA Technical Reports Server (NTRS)
Ding, R. Jeffrey (Inventor); Romine, Peter L. (Inventor); Oelgoetz, Peter A. (Inventor)
2002-01-01
A control is provided for a friction stir welding apparatus comprising a pin tool which includes a shoulder and a rotating pin extending outwardly from the shoulder of the pin tool and which, in use, is plunged into a workpiece formed contacting workpiece members to stir weld the members together. The control system controls the penetration of the pin tool into the workpiece members which are mounted on a support anvil. The control system includes a pin length controller for controlling pin length relative to the shoulder and for producing a corresponding pin length signal. A pin force sensor senses the force being exerted on the pin during welding and produces a corresponding actual pin force signal. A probe controller controls a probe extending outwardly from the pin, senses a parameter related to the distance between the probe and the supporting anvil and produces a corresponding probe signal. A workpiece standoff sensor senses the standoff distance between the workpiece and the standoff sensor and produces a corresponding standoff signal. A control unit receives the various signals, together with a weld schedule, and, based on these signals and the weld schedule, controls the pin length controller so as to control pin penetration into the workpiece.
Kawajiri, Maiko; Fujimoto, Shingo; Yoshida, Kohta; Yamahira, Kazunori; Kitano, Jun
2015-10-28
Traits involved in reproduction evolve rapidly and show great diversity among closely related species. However, the genetic mechanisms that underlie the diversification of courtship traits are mostly unknown. Japanese medaka fishes (Oryzias latipes) use anal fins to attract females and to grasp females during courtship; the males have longer anal fins with male-specific ossified papillary processes on the fin rays. However, anal fin morphology varies between populations: the southern populations tend to have longer anal fins and more processes than the northern populations. In the present study, we conducted quantitative trait locus (QTL) mapping to investigate the genetic architecture underlying the variation in the number of papillary processes of Japanese medaka fish and compared the QTL with previously identified QTL controlling anal fin length. First, we found that only a few QTL were shared between anal fin length and papillary process number. Second, we found that the numbers of papillary processes on different fin rays often were controlled by different QTL. Finally, we produced another independent cross and found that some QTL were repeatable between the two crosses, whereas others were specific to only one cross. These results suggest that variation in the number of papillary processes is polygenic and controlled by QTL that are distinct from those controlling anal fin length. Thus, different courtship traits in Japanese medaka share a small number of QTL and have the potential for independent evolution. Copyright © 2015 Kawajiri et al.
Huang, Yaping; Luo, Yurong; Liu, Jinhui; Gui, Saiyu; Wang, Mei; Liu, Wenbin; Peng, Liangyue; Xiao, Yamei
2017-01-01
Melanocyte stem cells are a population of immature cells which sustain the self-renewal and replenish the differentiated melanocytes. In this research, a light-colored region (LCR) is observed at the heel of caudal fin in juvenile crucian carp. By cutting off the caudal fin, the operated caudal fin can regenerate in accordance with the original pigment pattern from the retained LCR. As markers of stem cells, Oct4 and Sox2 have been found to be highly expressed in the LCR as well as Mitfa, a label of the melanoblasts. In vitro, Mitfa + melanoblasts are observed in the cells which are derived from the LCR and transfected with Mitfa-EGFP reporter by using Tol2 transposon system. Furthermore, by real-time qPCR, it is shown that the level of sox2 mRNA is gradually decreased from the LCR to proximal and distal caudal fin, and that of mitfa mRNA in the proximal caudal fin (PCF) is higher than that in the LCR, while it is the lowest in the distal caudal fin. Hence, we propose that the LCR is a pigment progenitor niche, sending melanocytes to the distal of caudal fin, which gradually emerges as caudal fin grow. We reveal that the LCR of caudal fin might be a niche of pigment progenitors, and contribute to pigment-producing stem cells in crucian carp. © 2016 International Federation for Cell Biology.
NASA Astrophysics Data System (ADS)
Liu, Hanlin; Curet, Oscar
2016-11-01
Effective control of propulsive undulating fins has the potential to enhance the maneuverability and efficiency of underwater vehicles allowing them to navigate in more complex environments. Aquatic animals using this type of propulsion are able to perform complex maneuvers by sending different traveling waves along one or multiple elongated fins. Recent work has investigated the propulsive forces, the hydrodynamics and the efficiency of an undulating ribbon fin. However, it is still not understood how different traveling wave shapes along the fin can be used to control the hydrodynamic forces and torques to perform different maneuvers. In this work, we study the effect of traveling wave shapes on the hydrodynamic forces and torques, swimming speed, maneuver control and propulsive performance of an underwater vehicle propelled by an undulating fin. The underwater robot propels by actuating a fin that is composed of sixteen independent rays interconnected with a flexible membrane. The hull contains all the electronics, batteries, motors and sensors. The underwater vehicle was tested in a water tank-flume facility. In a series of experiments, we measured the motion of the vessel and the power consumption for different traveling wave patterns. In addition, we measured the flow around the fin using Particle Image Velocimetry. We present the results concerning the power distribution along the fin, propulsive efficiency, free-swimming speed and pitch control based on different fin kinematics. National Science Foundation under Grant No. 1420774.
Oil-flow study of a Space Shuttle orbiter tip-fin controller
NASA Technical Reports Server (NTRS)
Helms, V. T., III
1983-01-01
Possible use of tip-fin controllers instead of a vertical tail on advanced winged entry vehicles was examined. Elimination of the vertical tail and using tip-fins offers the advantages of positive yaw control at high angles of attack and a potential weight savings. Oil-flow technique was used to obtain surface flow patterns on a tip-fin installed on a 0.01-scale Space Shuttle orbiter model for the purpose of assessing the extent of flow interference effects on the wing and tip-fin which might lead to serious heating problems. Tests were conducted in air at Mach 10 for a free-stream Reynolds numbers of .000113 at 20, 30, and 40 degree angle of attack and sideslip angles of 0 and 2 degree. Elevon deflections of -10, 0, and 10 degree and tip-fin control-surface deflections of 0, 20, and 40 degree were employed. Test results were also used to aid in the interpretation of heating data obtained on a Shuttle orbiter tip-fin on another model in a different facility. A limited comparison of oil-flow patterns and heat-transfer data is included. It was determined that elevon deflection angles from -10 to 10 degree and sideslip angles up to 2 degree have very little effect on tip-fin surface flow patterns. Also, there is a minimum of interference between the tip-fin and the wing. The most significant flow interactions occur on the tip-fin onboard surface as a result of its control-surface deflections.
Characteristics and formation mechanism for stainless steel fiber with periodic micro-fins
NASA Astrophysics Data System (ADS)
Tang, Tao; Wan, Zhenping; Lu, Longsheng; Tang, Yong
2016-05-01
Metal fibers have been widely used in many industrial applications due to their unique advantages. In certain applications, such as catalyst supports or orthopedic implants, a rough surface or tiny outshoots on the surface of metal fibers to increase surface area are needed. However, it has not been concerned about the surface morphologies of metal fiber in the current research of metal fiber manufacturing. In this paper, a special multi-tooth tool composed of a row of triangular tiny teeth is designed. The entire cutting layer of multi-tooth tool bifurcates into several thin cutting layers due to tiny teeth involved in cutting. As a result, several stainless steel fibers with periodic micro-fins are produced simultaneously. Morphology of periodic micro-fins is found to be diverse and can be classified into three categories: unilateral plane, unilateral tapering and bilateral. There are two forming mechanisms for the micro-fins. One is that periodic burrs remained on the free side of cutting layer of a tiny tooth create micro-fins of stainless steel fiber produced by the next neighboring tiny tooth; the other is that the connections between two fibers stuck together come to be micro-fins if the two fibers are finally detached. Influence of cutting conditions on formation of micro-fins is investigated. Experimental results show that cutting depth has no significant effect on micro-fin formation, high cutting speed is conducive to micro-fin formation, and feed should be between 0.12 mm/r and 0.2 mm/r to reliably obtain stainless steel fiber with micro-fins. This research presents a new pattern of stainless steel fiber characterized by periodic micro-fins formed on the edge of fiber and its manufacturing method.
NASA Astrophysics Data System (ADS)
Othman, Nurul Aida Farhana; Hatta, Sharifah Fatmadiana Wan Muhamad; Soin, Norhayati
2018-04-01
Stress-engineered fin-shaped field effect transistors (FinFET) using germanium (Ge) is a promising performance booster to replace silicon (Si) due to its high holes mobility. This paper presents a three-dimensional simulation by the Sentaurus technology computer-aided design to study the effects of stressors—channel stress, stress-relaxed buffer (SRB), and source/drain (S/D) epitaxial stress—on different bases of FinFET, specifically silicon germanium (SiGe) and Ge-based, whereby the latter is achieved by manipulating the Ge mole fraction inside the three layers; their effects on the devices' figures-of-merits were recorded. The simulation generates an advanced calibration process, by which the drift diffusion simulation was adopted for ballistic transport effects. The results show that current enhancement in p-type FinFET (p-FinFET) with 110% is almost twice that in n-type FinFET (n-FinFET) with 57%, with increasing strain inside the channel suggesting that the use of strain is more effective for holes. In SiGe-based n-FinFET, the use of a high-strained SRB layer can improve the drive current up to 112%, while the high-strain S/D epitaxial for Ge-based p-FinFET can enhance the on-state current to 262%. Further investigations show that the channel and S/D doping are affecting the performances of SiGe-based FinFET with similar importance. It is observed that doping concentrations play an important role in threshold voltage adjustment as well as in drive current and subthreshold leakage improvements.
Acre, Matthew R.; Alejandrez, Celeste; East, Jessica; Massure, Wade A.; Miyazono, S.; Pease, Jessica E.; Roesler, Elizabeth L.; Williams, H.M.; Grabowski, Timothy B.
2017-01-01
Evaluating the precision of age estimates generated by different readers and different calcified structures is an important part of generating reliable estimations of growth, recruitment, and mortality for fish populations. Understanding the potential loss of precision associated with using structures harvested without sacrificing individuals, such as scales or fin rays, is particularly important when working with imperiled species, such as Cycleptus elongatus (Blue Sucker). We collected otoliths (lapilli), scales, and the first fin rays of the dorsal, anal, pelvic, and pectoral fins of 9 Blue Suckers. We generated age estimates from each structure by both experienced (n = 5) and novice (n = 4) readers. We found that, independent of the structure used to generate the age estimates, the mean coefficient of variation (CV) of experienced readers was approximately 29% lower than that of novice readers. Further, the mean CV of age estimates generated from pectoral-fin rays, pelvic-fin rays, and scales were statistically indistinguishable and less than those of dorsal-fin rays, anal-fin rays, and otoliths. Anal-, dorsal-, and pelvic-fin rays and scales underestimated age compared to otoliths, but age estimates from pectoral-fin rays were comparable to those from otoliths. Skill level, structure, and fish total-length influenced reader precision between subsequent reads of the same aging structure from a particular fish. Using structures that can be harvested non-lethally to estimate the age of Blue Sucker can provide reliable and reproducible results, similar to those that would be expected from using otoliths. Therefore, we recommend the use of pectoral-fin rays as a non-lethal method to obtain age estimates for Blue Suckers.
Heude, Églantine; Shaikho, Sarah; Ekker, Marc
2014-01-01
The Dlx5 and Dlx6 genes encode homeodomain transcription factors essential for the proper development of limbs in mammalian species. However, the role of their teleost counterparts in fin development has received little attention. Here, we show that dlx5a is an early marker of apical ectodermal cells of the pectoral fin buds and of the median fin fold, but also of cleithrum precursor cells during pectoral girdle development. We propose that early median fin fold establishment results from the medial convergence of dlx5a-expressing cells at the lateral edges of the neural keel. Expression analysis also shows involvement of dlx5a during appendage skeletogenesis. Using morpholino-mediated knock down, we demonstrate that disrupted dlx5a/6a function results in pectoral fin agenesis associated with misexpression of bmp4, fgf8a, and1 and msx genes. In contrast, the median fin fold presents defects in mesenchymal cell migration and actinotrichia formation, whereas the initial specification seems to occur normally. Our results demonstrate that the dlx5a/6a genes are essential for the induction of pectoral fin outgrowth, but are not required during median fin fold specification. The dlx5a/6a knock down also causes a failure of cleithrum formation associated with a drastic loss of runx2b and col10a1 expression. The data indicate distinct requirements for dlx5a/6a during median and pectoral fin development suggesting that initiation of unpaired and paired fin formation are not directed through the same molecular mechanisms. Our results refocus arguments on the mechanistic basis of paired appendage genesis during vertebrate evolution. PMID:24858471
Parametric study of graphite foam fins and application in heat exchangers
NASA Astrophysics Data System (ADS)
Collins, Michael
This thesis focuses on the simulation and experimental studies of finned graphite foam extended surfaces to test their heat transfer characteristics and potential applications in condensers. Different fin designs were developed to conduct a parametric study on the thermal effectiveness with respect to thickness, spacing and fin offset angle. Each fin design was computationally simulated to estimate the heat transfer under specific conditions. The simulations showed that this optimal fin configuration could conduct more than 297% the amount of thermal energy as compared to straight aluminum fins. Graphite foam fins were then implemented into a simulation of the condenser system. The condenser was simulated with six different orientations of baffles to examine the incoming vapor and resulting two-phase flow patterns. The simulations showed that using both horizontal and vertical baffling provided the configuration with the highest heat transfer and minimized the bypass regions where the vapor would circumvent the graphite foam. This baffle configuration increased the amount of vapor flow through the inner graphite fins and cold water pipes, which gave this configuration the highest heat transfer. The results from experimental tests using the condenser system confirmed that using three baffles will increase performance consistent with the simulation results. The experimental data showed that the condenser using graphite foam had five times the heat transfer compared to the condenser using only aluminum fins. Incorporating baffles into the condenser using graphite foam enabled this system to conduct nearly ten times more heat transfer than the condenser system which only had aluminum fins without baffles. The results from this research indicate that graphite foam is a far superior material heat transfer enhancement material for heat transfer compared to aluminum used as an extended surface. The longitudinal and horizontal baffles incorporated into the condenser system greatly enhanced the heat transfer because of the increased interaction with the porous graphite foam fins.
NASA Astrophysics Data System (ADS)
Patil, Harshal Bhauso; Dingare, Sunil Vishnu
2018-03-01
Heat exchange upgrade is a vital territory of research area. Utilization of reasonable systems can bring about noteworthy specialized points of interest coming about reserve funds of cost. Rectangular plates are viewed as best balance arrangement utilized for heat exchange improvement. This gives an enlargement strategy to heat exchange with beginning of limit layer and vortex development. To assess and look at the rate of heat exchange enhancement by rectangular plate fins with differing inclinations (0°-30°-60°), shifting Re and heat supply under forced convection are the principle destinations of this study. The study is done by fluctuating introductions of fins with various inclinations, input heat supply and Re under forced convection. The coefficient of heat transfer increments observed with the expansion in air speed for all the examined designs. The coefficient of the heat transfer is discovered higher at the edge of introduction of fins at 30° for inline arrangement and 0° for staggered arrangement. Looking at both the arrangements, it is discovered that the heat transfer coefficient in 0° fin staggered arrangement is about 17% higher than 30° inline arrangement and 76% higher than the vertical plate fin. For plate fin heat sink, boundary layer formation and growth results in decrease of the coefficient of heat transfer in forced convection. This issue is overcome by accommodating some rectangular fins on the plate fin. It brings about increment of heat transfer coefficient of the RPFHS under the states of trial factors. As indicated by past research, it is discovered that examination of the plate fin heat sink with various sorts of fins for horizontal orientation is done yet but this investigation expects to discover the upgrade of transfer coefficient of plate fin heat sink for its vertical position with rectangular plates at different inclinations under the shifting scopes of heat input supply, fin arrangements and Reynolds number (Re).
Relying on fin erosion to identify hatchery-reared brown trout in a Tennessee river
Meerbeek, Jonathan R.; Bettoli, Phillip William
2012-01-01
Hatchery-induced fin erosion can be used to identify recently stocked catchable-size brown trout Salmo trutta during annual surveys to qualitatively estimate contributions to a fishery. However, little is known about the longevity of this mark and its effectiveness as a short-term (≤ 1 year) mass-marking technique. We evaluated hatchery-induced pectoral fin erosion as a mass-marking technique for short-term stocking evaluations by stocking microtagged brown trout in a tailwater and repeatedly sampling those fish to observe and measure their pectoral fins. At Dale Hollow National Fish Hatchery, 99.1% (228 of 230) of microtagged brown trout in outdoor concrete raceways had eroded pectoral fins 1 d prior to stocking. Between 34 and 68 microtagged and 26-35 wild brown trout were collected during eight subsequent electrofishing samples. In a blind test based on visual examination of pectoral fins at up to 322 d poststocking, one observer correctly identified 91.7% to 100.0% (mean of 96.9%) of microtagged brown trout prior to checking for microtags. In the laboratory, pectoral fin length and width measurements were recorded to statistically compare the fin measurements of wild and microtagged hatchery brown trout. With only one exception, all pectoral fin measurements on each date averaged significantly larger for wild trout than for microtagged brown trout. Based on the number of pectoral fin measurements falling below 95% prediction intervals, 93.7% (148 of 158) of microtagged trout were correctly identified as hatchery fish based on regression models up to 160 d poststocking. Only 72.2% (70 of 97) of microtagged trout were identified correctly after 160 d based on pectoral fin measurements and the regression models. We concluded that visual examination of pectoral fin erosion was a very effective way to identify stocked brown trout for up to 322 d poststocking.
Laminar heat transfer in annular sector ducts
DOE Office of Scientific and Technical Information (OSTI.GOV)
Soliman, H.M.
1987-02-01
The continuing interest in compact heat exchangeers has created the need for friction factor and Nusselt number data for different passage shapes. It has long been recognized that circular tube results are generally not applicable to noncircular passages even when the hydraulic diameter is used as the characteristic dimension. Hence, design data should be generated for each passage individually, and a good source of such information is Shah and London. One duct geometry for which complete design information does not appear to be available in the open literature is that of annular sector ducts. Such configuration is encountered in multipassagemore » internally finned tubes and many other compact het exchanger applications. The fluid flow problem for this configuration has been solved by Sparrow et al., and more recently by Niida. However, to the beest of the author's knowledge, the heat transfer results are not available yet. The purpose of this note is to summarize the analysis and results of fluid flow and heat transfer in annular sector ducts.« less
NASA Astrophysics Data System (ADS)
Cziczo, D. J.; Moehler, O.; DeMott, P. J.
2015-12-01
The relationship of ambient aerosol particles to the formation of ice-containing clouds is one of the largest uncertainties in understanding climate. This is due to several poorly understood processes including the microphysics of how particles nucleate ice, the number of effective heterogeneous ice nuclei and their atmospheric distribution, the role of anthropogenic activities in producing or changing the behavior of ice forming particles and the interplay between effective heterogeneous ice nuclei and homogeneous ice formation. Our team recently completed a three-part international workshop to improve our understanding of atmospheric ice formation. Termed the Fifth International Ice Nucleation (FIN) Workshops, our motivation was the limited number of measurements and a lack of understanding of how to compare data acquired by different groups. The first activity, termed FIN1, addressed the characterization of ice nucleating particle size, number and chemical composition. FIN2 addressed the determination of ice nucleating particle number density. Groups modeling ice nucleation joined FIN2 to provide insight on measurements critically needed to model atmospheric ice nucleation and to understand the performance of ice chambers. FIN1 and FIN2 took place at the Aerosol Interaction and Dynamics in the Atmosphere (AIDA) chamber at the Karlsruhe Institute of Technology. A particular emphasis of FIN1 and FIN2 was the use of 'blind' intercomparisons using a highly characterized, but unknown to the instrument operators, aerosol sample. The third activity, FIN3, took place at the Desert Research Institute's Storm Peak Laboratory (SPL). A high elevation site not subject to local emissions, SPL allowed for a comparison of ice chambers and subsequent analysis of the ice residuals under the challenging conditions of low particle loading, temperature and pressure found in the atmosphere. The presentation focuses on the improvement in understanding how mass spectra from different instruments can be compared from FIN1 and FIN3. The complementary nature of different ice chamber to access the diverse regimes of temperature and relative humidity space will also be discussed. As a result of the FIN Workshops we believe the performance of instruments in the field can now be quantified and compared.
Hale, Melina E
2014-07-01
An animal may experience strikingly different functional demands on its body's systems through development. One way of meeting those demands is with temporary, stage-specific adaptations. This strategy requires the animal to develop appropriate morphological states or physiological pathways that address transient functional demands as well as processes that transition morphology, physiology, and function to that of the mature form. Recent research on ray-finned (actinopterygian) fishes is a developmental transition in function of the pectoral fin, thereby providing an opportunity to examine how an organism copes with changes in the roles of its morphology between stages of its life history. As larvae, zebrafish alternate their pectoral fins in coordination with the body axis during slow swimming. The movements of their fins do not appear to contribute to the production of thrust or to stability but instead exchange fluid near the body for cutaneous respiration. The morphology of the larval fin includes a simple stage-specific endoskeletal disc overlaid by fan-shaped adductor and abductor muscles. In contrast, the musculoskeletal system of the mature fin consists of a suite of muscles and bones. Fins are extended laterally during slow swimming of the adult, without the distinct, high-amplitude left-right fin alternation of the larval fin. The morphological and functional transition of the pectoral fin occurs through juvenile development. Early in this period, at about 3 weeks post-fertilization, the gills take over respiratory function, presumably freeing the fins for other roles. Kinematic data suggest that the loss of respiratory function does not lead to a rapid switch in patterns of fin movement but rather that both morphology and movement transition gradually through the juvenile stage of development. Studies relating structure to function often focus on stable systems that are arguably well adapted for the roles they play. Examining how animals navigate transitional periods, when the link of structure to function may be less taut, provides insight both into how animals contend with such change and into the developmental pressures that shape mature form and function. © The Author 2014. Published by Oxford University Press on behalf of the Society for Integrative and Comparative Biology.
Neofytou, M; Sfakianakis, D G; Koumoundouros, G; Mylonas, C C; Kentouri, M
2017-09-01
The osteological development of the vertebral column and fins in shi drum Umbrina cirrosa was studied in order to improve knowledge for its introduction in Mediterranean aquaculture. The osteological development was studied in 171 individuals, of total length (L T ) from 2·7 to 30·2 mm that were reared under the mesocosm technique. Vertebral ontogeny starts at 3·4 and 4·0 mm L T , with the formation of the first cartilaginous neural and haemal arches, and spines, respectively, and is completed with the full attainment of epicentrals (12·5 mm L T ). The formation of vertebral centra occurs between 4·1 and 7·4 mm L T . Pectoral supports are the first fin elements to develop (3·0 mm L T ), followed by those of the caudal fin (3·8 mm L T ), pelvic fin (3·9 mm L T ) and finally by those of the dorsal and anal fins (4·5 mm L T ). The caudal fin is the first to develop fin rays and attain the full count of principal fin rays (4·5-6·8 mm L T ), but the last to be fully completed with the formation of procurrent fin rays (6·9-17·5 mm L T ). The next fins starting to present rays are the dorsal (5·3 mm L T ) and the pectoral fins (5·6 mm L T ), while the anal and pelvic fins are the last (5·7 mm L T ). Following the caudal principal fin rays (6·8 mm L T ), the dorsal, anal (6·9 mm L T ), pelvic (7·4 mm L T ) and pectoral fins (9·8 mm L T ) are the next with fully completed ray counts. Aggregation of qualitative changes, such as the appearance of cartilages, the beginning and the complement of the ossification process and the full complement of elements in U. cirrosa were measured as cumulative frequency counts. These measurements reveal three ontogenetic intervals: one very developmentally active period during early life stages (from 3 to 5·9 mm L T ), a second slower developmental period (from 6·0 to 8·9 mm L T ) and finally a period of ontogeny more focused on structure refinement up to metamorphosis and settlement (>9·0 mm L T ). © 2017 The Fisheries Society of the British Isles.
Apparatus for inspecting fuel elements
Oakley, David J.; Groves, Oliver J.; Kaiser, Bruce J.
1986-01-01
Disclosed is an alpha monitor usable in an automated nuclear fuel pin loading and processing unit. Fuel pins or other elongated pins are fed laterally into the alpha monitor in a singular fashion and are translated by a first roller assembly into a weld flare machining and decontamination substation not forming a part of the invention. Pins return and are lifted upwardly and transferred across to a combined pin lifting and electrode operating means which lifts the pins upwardly into a clamshell electrode assembly which is spread open by a combined pin lifting and electrode operating means. Once inserted the clamshell type electrode arrangement closes around the fuel pins so that inspection can occur. Fuel pins are inspected by charging electrodes to a negative potential and measuring the change in charge occurring when positively charged alpha particles strike the negatively charged electrodes. After inspection, the fuel pins are lowered by the pin lifting and electrode operating means into a second roller assembly which longitudinally conveys approved pins from the airtight enclosure in which the alpha monitor is mounted. If the fuel pins are rejected then they are moved laterally by a second transfer means and onto another system for further processing.
Apparatus for inspecting fuel elements
Kaiser, B.J.; Oakley, D.J.; Groves, O.J.
1984-12-21
This disclosure describes an alpha monitor usable in an automated nuclear fuel pin loading and processing unit. Fuel pins or other elongated pins are fed laterally into the alpha monitor in a singular fashion and are translated by a first roller assembly into a weld flare machining and decontamination substation not forming a part of the invention. Pins return and are lifted upwardly and transferred across to a combined pin lifting and electrode operating means which lifts the pins upwardly into a clamshell electrode assembly which is spread open by a combined pin lifting and electrode operating means. Once inserted the clamshell type electrode arrangement closes around the fuel pins so that inspection can occur. Fuel pins are inspected by charging electrodes to a negative potential and measuring the change in charge occurring when positively charged alpha particles strike the negatively charged electrodes. After inspection, the fuel pins are lowered by the pin lifting and electrode operating means into a second roller assembly which longitudinally conveys approved pins from the airtight enclosure in which the alpha monitor is mounted. If the fuel pins are rejected then they are moved laterally by a second transfer means and onto another system for further processing.
Pin routability and pin access analysis on standard cells for layout optimization
NASA Astrophysics Data System (ADS)
Chen, Jian; Wang, Jun; Zhu, ChengYu; Xu, Wei; Li, Shuai; Lin, Eason; Ou, Odie; Lai, Ya-Chieh; Qu, Shengrui
2018-03-01
At advanced process nodes, especially at sub-28nm technology, pin accessibility and routability of standard cells has become one of the most challenging design issues due to the limited router tracks and the increased pin density. If this issue can't be found and resolved during the cell design stage, the pin access problem will be very difficult to be fixed in implementation stage and will make the low efficiency for routing. In this paper, we will introduce a holistic approach for the pin accessibility scoring and routability analysis. For accessibility, the systematic calculator which assigns score for each pin will search the available access points, consider the surrounded router layers, basic design rule and allowed via geometry. Based on the score, the "bad" pins can be found and modified. On pin routability analysis, critical pin points (placing via on this point would lead to failed via insertion) will be searched out for either layout optimization guide or set as OBS for via insertion blocking. By using this pin routability and pin access analysis flow, we are able to improve the library quality and performance.
Flux pinning mechanism in codoped-MgB2 with Al2O3 and SiC
NASA Astrophysics Data System (ADS)
Kiafiroozkoohi, Narjess Sadat; Ghorbani, Shaban Reza; Arabi, Hadi
2018-05-01
MgB2 superconductor samples, co-doped with 0.02 wt of Al2O3 and 0.02 wt SiC, have been examined by M-H loop measurements and calculation of the critical current density based on the Bean model. Normalized volume pinning force, f = F/Fmax, as a function of the reduced magnetic field, h = H/Hmax has been obtained at each temperature. Hughochi flux pinning model, which was included the normal point pinning, the normal surface pinning, and the pinning based on spatial variation in the Ginzburg-Landau parameter, was used to study the flux pinning mechanisms. It was found that the Δκ effect and the normal point pinning mechanisms play the main role in the flux pinning at the magnetic field lower than Hmax and the contribution of the Δκ mechanism increases with the increasing temperature, while the contribution of normal point pinning mechanism decreases. At magnetic field larger than Hmax, the only mechanism that acts as the flux pinning was the normal surface pinning mechanism.
NASA Astrophysics Data System (ADS)
Mesalhy, O. M.; El-Sayed, Mostafa M.
2015-06-01
Flow and heat transfer characteristics of a plate-fin heat sink cooled by a rectangular impinging jet with different cross-sectional area were studied experimentally and numerically. The study concentrated on investigating the effect of jet width, fin numbers, and fin heights on thermal performance. Entropy generation minimization method was used to define the optimum design and operating conditions. It is found that, the jet width that minimizes entropy generation changes with heat sink height and fin numbers.
2015-09-30
1 DISTRIBUTION STATEMENT A. Approved for public release; distribution is unlimited. Large Scale Density Estimation of Blue and Fin Whales ...Utilizing Sparse Array Data to Develop and Implement a New Method for Estimating Blue and Fin Whale Density Len Thomas & Danielle Harris Centre...to develop and implement a new method for estimating blue and fin whale density that is effective over large spatial scales and is designed to cope
Remote control missile model test
NASA Technical Reports Server (NTRS)
Allen, Jerry M.; Shaw, David S.; Sawyer, Wallace C.
1989-01-01
An extremely large, systematic, axisymmetric body/tail fin data base was gathered through tests of an innovative missile model design which is described herein. These data were originally obtained for incorporation into a missile aerodynamics code based on engineering methods (Program MISSILE3), but can also be used as diagnostic test cases for developing computational methods because of the individual-fin data included in the data base. Detailed analysis of four sample cases from these data are presented to illustrate interesting individual-fin force and moment trends. These samples quantitatively show how bow shock, fin orientation, fin deflection, and body vortices can produce strong, unusual, and computationally challenging effects on individual fin loads. Comparisons between these data and calculations from the SWINT Euler code are also presented.
ESD testing of the 8S actuator (u)
DOE Office of Scientific and Technical Information (OSTI.GOV)
Mchugh, Douglas C
2010-12-03
The 8S actuator is a hot-wire initiated explosive component used to drive the W76-1 2X Acorn 1V valve. It is known to be safe from human electrostatic discharge (ESD) pin-to-pin and all pin-to-cup stimuli as well as 1 amp/1 watt safe. However low impedance (furniture) ESD stimuli applied pin-to-pin has not been evaluated. Components were tested and the results analyzed. The 8S actuator has been shown to be immune to human and severe furniture ESD, whether applied pin-to-pin or pin-to-cup.
IGF2BP2 variations influence repaglinide response and risk of type 2 diabetes in Chinese population.
Huang, Qiong; Yin, Ji-ye; Dai, Xing-ping; Pei, Qi; Dong, Min; Zhou, Zhi-guang; Huang, Xi; Yu, Min; Zhou, Hong-hao; Liu, Zhao-qian
2010-06-01
To investigate whether the insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) rs1470579 and rs4402960 polymorphisms are associated with the development of type 2 diabetes mellitus (T2DM) and the repaglinide therapeutic efficacy in Chinese T2DM patients. A case-control study of a total of 350 patients with T2DM and 207 healthy volunteers was conducted to identify their genotypes for the IGF2BP2 rs1470579 and rs4402960 polymorphisms using a polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) assay. Forty-two patients were randomly selected to undergo an 8-week repaglinide treatment (3 mg/d). Fasting plasma glucose (FPG), postprandial plasma glucose (PPG), glycated hemoglobin (HbAlc), fasting serum insulin (FINS), postprandial serum insulin (PINS), homeostasis model assessment for insulin resistance (HOMA-IR), serum triglyceride, total cholesterol (TC), low-density lipoprotein-cholesterol (LDL-c), and high-density lipoprotein-cholesterol (HDL-c) were determined before and after repaglinide treatment. The frequencies of the IGF2BP2 rs1470579 C allele and the rs4402960 T allele were higher in T2DM patients than in healthy controls (P<0.05 and P<0.001, respectively). The effects of the repaglinide treatment on FPG (P<0.05) and PPG (P<0.05) were reduced in patients with the rs1470579 AC+CC genotypes compared with AA genotype carriers. Patients with the rs4402960 GT+TT genotypes exhibited an enhanced effect of repaglinide treatment on PINS (P<0.01) compared with GG genotype subjects. The IGF2BP2 rs1470579 and rs4402960 polymorphisms may be associated with the development of T2DM, and these polymorphisms may affect the therapeutic efficacy of repaglinide in Chinese T2DM patients.
IGF2BP2 variations influence repaglinide response and risk of type 2 diabetes in Chinese population
Huang, Qiong; Yin, Ji-ye; Dai, Xing-ping; Pei, Qi; Dong, Min; Zhou, Zhi-guang; Huang, Xi; Yu, Min; Zhou, Hong-hao; Liu, Zhao-qian
2010-01-01
Aim: To investigate whether the insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) rs1470579 and rs4402960 polymorphisms are associated with the development of type 2 diabetes mellitus (T2DM) and the repaglinide therapeutic efficacy in Chinese T2DM patients. Methods: A case-control study of a total of 350 patients with T2DM and 207 healthy volunteers was conducted to identify their genotypes for the IGF2BP2 rs1470579 and rs4402960 polymorphisms using a polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) assay. Forty-two patients were randomly selected to undergo an 8-week repaglinide treatment (3 mg/d). Fasting plasma glucose (FPG), postprandial plasma glucose (PPG), glycated hemoglobin (HbAlc), fasting serum insulin (FINS), postprandial serum insulin (PINS), homeostasis model assessment for insulin resistance (HOMA-IR), serum triglyceride, total cholesterol (TC), low-density lipoprotein-cholesterol (LDL-c), and high-density lipoprotein-cholesterol (HDL-c) were determined before and after repaglinide treatment. Results: The frequencies of the IGF2BP2 rs1470579 C allele and the rs4402960 T allele were higher in T2DM patients than in healthy controls (P<0.05 and P<0.001, respectively). The effects of the repaglinide treatment on FPG (P<0.05) and PPG (P<0.05) were reduced in patients with the rs1470579 AC+CC genotypes compared with AA genotype carriers. Patients with the rs4402960 GT+TT genotypes exhibited an enhanced effect of repaglinide treatment on PINS (P<0.01) compared with GG genotype subjects. Conclusion: The IGF2BP2 rs1470579 and rs4402960 polymorphisms may be associated with the development of T2DM, and these polymorphisms may affect the therapeutic efficacy of repaglinide in Chinese T2DM patients. PMID:20523342
Genome-wide identification and evolution of the PIN-FORMED (PIN) gene family in Glycine max.
Liu, Yuan; Wei, Haichao
2017-07-01
Soybean (Glycine max) is one of the most important crop plants. Wild and cultivated soybean varieties have significant differences worth further investigation, such as plant morphology, seed size, and seed coat development; these characters may be related to auxin biology. The PIN gene family encodes essential transport proteins in cell-to-cell auxin transport, but little research on soybean PIN genes (GmPIN genes) has been done, especially with respect to the evolution and differences between wild and cultivated soybean. In this study, we retrieved 23 GmPIN genes from the latest updated G. max genome database; six GmPIN protein sequences were changed compared with the previous database. Based on the Plant Genome Duplication Database, 18 GmPIN genes have been involved in segment duplication. Three pairs of GmPIN genes arose after the second soybean genome duplication, and six occurred after the first genome duplication. The duplicated GmPIN genes retained similar expression patterns. All the duplicated GmPIN genes experienced purifying selection (K a /K s < 1) to prevent accumulation of non-synonymous mutations and thus remained more similar. In addition, we also focused on the artificial selection of the soybean PIN genes. Five artificially selected GmPIN genes were identified by comparing the genome sequence of 17 wild and 14 cultivated soybean varieties. Our research provides useful and comprehensive basic information for understanding GmPIN genes.
Reduction of halo pin site morbidity with a new pin care regimen.
Kazi, Hussain Anthony; de Matas, Marcus; Pillay, Robin
2013-06-01
A retrospective analysis of halo device associated morbidity over a 4-year period. To assess the impact of a new pin care regimen on halo pin site related morbidity. Halo orthosis treatment still has a role in cervical spine pathology, despite increasing possibilities of open surgical treatment. Published figures for pin site infection range from 12% to 22% with pin loosening from 7% to 50%. We assessed the outcome of a new pin care regimen on morbidity associated with halo spinal orthoses, using a retrospective cohort study from 2001 to 2004. In the last two years, our pin care regimen was changed. This involved pin site care using chlorhexidene & regular torque checking as part of a standard protocol. Previously, povidone iodine was used as skin preparation in theatre, followed by regular sterile saline cleansing when pin sites became encrusted with blood. There were 37 patients in the series, the median age was 49 (range, 22-83) and 20 patients were male. The overall infection rate prior to the new pin care protocol was 30% (n=6) and after the introduction, it dropped to 5.9% (n=1). This difference was statistically significant (p<0.05). Pin loosening occurred in one patient in the group prior to the formal pin care protocol (3%) and none thereafter. Reduced morbidity from halo use can be achieved with a modified pin cleansing and tightening regimen.
The prolyl isomerase Pin1 increases β-cell proliferation and enhances insulin secretion.
Nakatsu, Yusuke; Mori, Keiichi; Matsunaga, Yasuka; Yamamotoya, Takeshi; Ueda, Koji; Inoue, Yuki; Mitsuzaki-Miyoshi, Keiko; Sakoda, Hideyuki; Fujishiro, Midori; Yamaguchi, Suguru; Kushiyama, Akifumi; Ono, Hiraku; Ishihara, Hisamitsu; Asano, Tomoichiro
2017-07-14
The prolyl isomerase Pin1 binds to the phosphorylated Ser/Thr-Pro motif of target proteins and enhances their cis-trans conversion. This report is the first to show that Pin1 expression in pancreatic β cells is markedly elevated by high-fat diet feeding and in ob/ob mice. To elucidate the role of Pin1 in pancreatic β cells, we generated β-cell-specific Pin1 KO (βPin1 KO) mice. These mutant mice showed exacerbation of glucose intolerance but had normal insulin sensitivity. We identified two independent factors underlying impaired insulin secretion in the βPin1 KO mice. Pin1 enhanced pancreatic β-cell proliferation, as indicated by a reduced β-cell mass in βPin1 KO mice compared with control mice. Moreover, a diet high in fat and sucrose failed to increase pancreatic β-cell growth in the βPin1 KO mice, an observation to which up-regulation of the cell cycle protein cyclin D appeared to contribute. The other role of Pin1 was to activate the insulin-secretory step: Pin1 KO β cells showed impairments in glucose- and KCl-induced elevation of the intracellular Ca 2+ concentration and insulin secretion. We also identified salt-inducible kinase 2 (SIK2) as a Pin1-binding protein that affected the regulation of Ca 2+ influx and found Pin1 to enhance SIK2 kinase activity, resulting in a decrease in p35 protein, a negative regulator of Ca 2+ influx. Taken together, our observations demonstrate critical roles of Pin1 in pancreatic β cells and that Pin1 both promotes β-cell proliferation and activates insulin secretion. © 2017 by The American Society for Biochemistry and Molecular Biology, Inc.
Lewis, Richard A.
1980-01-01
A target for a proton beam which is capable of generating neutrons for absorption in a breeding blanket includes a plurality of solid pins formed of a neutron emissive target material disposed parallel to the path of the beam and which are arranged axially in a plurality of layers so that pins in each layer are offset with respect to pins in all other layers, enough layers being used so that each proton in the beam will strike at least one pin with means being provided to cool the pins. For a 300 mA, 1 GeV beam (300 MW), stainless steel pins, 12 inches long and 0.23 inches in diameter are arranged in triangular array in six layers with one sixth of the pins in each layer, the number of pins being such that the entire cross sectional area of the beam is covered by the pins with minimum overlap of pins.
The effect of temperature on pinning mechanisms in HTS composites
NASA Astrophysics Data System (ADS)
Sotnikova, A. P.; Rudnev, I. A.
2016-09-01
Pinning mechanism in samples of second generation tapes (2G) of high-temperature superconductors (HTS) was studied The critical current and the pinning force were calculated from the magnetization curves measured in the temperature range of 4.2 - 77 K in magnetic fields up to 14 Tesla using vibration sample magnetometer. To determine the pinning mechanism the dependences of pinning force on magnetic field were constructed according to the Dew-Hughes model and Kramer's rule. The obtained dependences revealed a significant influence of the temperature on effectiveness of different types of pinning. At low temperatures the 2G HTS tapes of different manufacturers demonstrated an equal efficiency of the pinning centers but with temperature increase the differences in pinning mechanisms as well as in properties and effectiveness of the pinning centers become obvious. The influence of the pinning mechanism on the energy losses in HTS tapes was shown.
Gate length scaling optimization of FinFETs
NASA Astrophysics Data System (ADS)
Chen, Shoumian; Shang, Enming; Hu, Shaojian
2018-06-01
This paper introduces a device performance optimization approach for the FinFET through optimization of the gate length. As a result of reducing the gate length, the leakage current (Ioff) increases, and consequently, the stress along the channel enhances which leads to an increase in the drive current (Isat) of the PMOS. In order to sustain Ioff, work function is adjusted to offset the effect of the increased stress. Changing the gate length of the transistor yields different drive currents when the leakage current is fixed by adjusting the work function. For a given device, an optimal gate length is found to provide the highest drive current. As an example, for a standard performance device with Ioff = 1 nA/um, the best performance Isat = 856 uA/um is at L = 34 nm for 14 nm FinFET and Isat = 1130 uA/um at L = 21 nm for 7 nm FinFET. A 7 nm FinFET will exhibit performance boost of 32% comparing with 14 nm FinFET. However, applying the same method to a 5 nm FinFET, the performance boosting is out of expectance comparing to the 7 nm FinFET, which is due to the severe short-channel-effect and the exhausted channel stress in the FinFET.
Chuang, Po-Shun; Hung, Tzu-Chiao; Chang, Hung-An; Huang, Chien-Kang; Shiao, Jen-Chieh
2016-01-01
The increasing consumption of shark products, along with the shark's fishing vulnerabilities, has led to the decrease in certain shark populations. In this study we used a DNA barcoding method to identify the species of shark landings at fishing ports, shark fin products in retail stores, and shark fins detained by Taiwan customs. In total we identified 23, 24, and 14 species from 231 fishing landings, 316 fin products, and 113 detained shark fins, respectively. All the three sample sources were dominated by Prionace glauca, which accounted for more than 30% of the collected samples. Over 60% of the species identified in the fin products also appeared in the port landings, suggesting the domestic-dominance of shark fin products in Taiwan. However, international trade also contributes a certain proportion of the fin product markets, as four species identified from the shark fin products are not found in Taiwan's waters, and some domestic-available species were also found in the customs-detained sample. In addition to the species identification, we also found geographical differentiation in the cox1 gene of the common thresher sharks (Alopias vulpinus), the pelagic thresher shark (A. pelagicus), the smooth hammerhead shark (Sphyrna zygaena), and the scalloped hammerhead shark (S. lewini). This result might allow fishing authorities to more effectively trace the origins as well as enforce the management and conservation of these sharks.
Rocha-Estrada, J G; Córdova-Murueta, J H; García-Carreño, F L
2010-10-01
Functional properties of protein from mantle and fin of the jumbo squid Dosidicus gigas were explained based on microscopic muscle fiber and protein fractions profiles as observed in SDS-PAGE. Fin has higher content of connective tissue and complex fiber arrangement, and we observed higher hardness of fin gels as expected. Myosin heavy chain (MHC) was found in sarcoplasmic, myofibril and soluble-in-alkali fractions of mantle and only in sarcoplasmic and soluble-in-alkali fractions of fin. An additive effect of salt concentration and pH affected the solubility and foaming properties. Fin and mantle proteins yielded similar results in solubility tests, but significant differences occurred for specific pH and concentrations of salt. Foaming capacity was proportional to solubility; foam stability was also affected by pH and salt concentration. Hardness and fracture strength of fin gels were significantly higher than mantle gels; gels from proteins of both tissues reached the highest level in the folding test. Structural and molecular properties, such as MHC and paramyosin solubility, arrangement of muscle fibers and the content of connective tissue were useful to explain the differences observed in these protein properties. High-strength gels can be formed from squid mantle or fin muscle. Fin displayed similar or better properties than mantle in all tests.
Radiation Effects in Advanced Multiple Gate and Silicon-on-Insulator Transistors
NASA Astrophysics Data System (ADS)
Simoen, Eddy; Gaillardin, Marc; Paillet, Philippe; Reed, Robert A.; Schrimpf, Ron D.; Alles, Michael L.; El-Mamouni, Farah; Fleetwood, Daniel M.; Griffoni, Alessio; Claeys, Cor
2013-06-01
The aim of this review paper is to describe in a comprehensive manner the current understanding of the radiation response of state-of-the-art Silicon-on-Insulator (SOI) and FinFET CMOS technologies. Total Ionizing Dose (TID) response, heavy-ion microdose effects and single-event effects (SEEs) will be discussed. It is shown that a very high TID tolerance can be achieved by narrow-fin SOI FinFET architectures, while bulk FinFETs may exhibit similar TID response to the planar devices. Due to the vertical nature of FinFETs, a specific heavy-ion response can be obtained, whereby the angle of incidence becomes highly important with respect to the vertical sidewall gates. With respect to SEE, the buried oxide in the SOI FinFETs suppresses the diffusion tails from the charge collection in the substrate compared to the planar bulk FinFET devices. Channel lengths and fin widths are now comparable to, or smaller than the dimensions of the region affected by the single ionizing ions or lasers used in testing. This gives rise to a high degree of sensitivity to individual device parameters and source-drain shunting during ion-beam or laser-beam SEE testing. Simulations are used to illuminate the mechanisms observed in radiation testing and the progress and needs for the numerical modeling/simulation of the radiation response of advanced SOI and FinFET transistors are highlighted.
Federal Register 2010, 2011, 2012, 2013, 2014
2013-06-17
..., transferring or receiving fins from one vessel to another at sea unless the fins are naturally attached to the..., to provide additional time for various stakeholders and other members of the public to submit..., transferring or receiving fins from one vessel to another at sea unless the fins are naturally attached to the...
NASA Astrophysics Data System (ADS)
Liu, Ya; Ma, Yongting; Bhattacharya, Amitabh; Kuksenok, Olga; He, Ximin; Aizenberg, Joanna; Balazs, Anna
2013-11-01
In biomimetics, designing an effective ``catch and release'' device for the selective removal of target species from the surrounding solution is critical for developing autonomous sensors and sorters. Using computational simulation, we model an array of oscillating fins that are tethered on the floor of a microchannel and immersed in a binary-fluid stream. During the oscillation, the fins with the specific chemical wetting reach the upper fluid when they are upright and are entirely within the lower stream when they are tilted. We introduce specific adhesive interactions between the fins and particulates in the solution and determine conditions where the oscillating fins can selectively bind (``catch'') target nanoparticles within the upper fluid stream and then release these particles into the lower stream. We isolate the effects of chemical wetting on the fins (e.g., wetting contact angle between fins and fluid) and mechanical parameters (e.g., frequency of fins' oscillations) that lead to the efficient extraction of target species from the upper stream and placement into the lower fluid. Our understanding provides fundamental insights into the system's complex dynamics and mechanism for detection, separation, and purification of multi-component mixtures.
NASA Astrophysics Data System (ADS)
Barforoush, M. S. M.; Saedodin, S.
2018-01-01
This article investigates the thermal performance of convective-radiative annular fins with a step reduction in local cross section (SRC). The thermal conductivity of the fin's material is assumed to be a linear function of temperature, and heat transfer coefficient is assumed to be a power-law function of surface temperature. Moreover, nonzero convection and radiation sink temperatures are included in the mathematical model of the energy equation. The well-known differential transformation method (DTM) is used to derive the analytical solution. An exact analytical solution for a special case is derived to prove the validity of the obtained results from the DTM. The model provided here is a more realistic representation of SRC annular fins in actual engineering practices. Effects of many parameters such as conduction-convection parameters, conduction-radiation parameter and sink temperature, and also some parameters which deal with step fins such as thickness parameter and dimensionless parameter describing the position of junction in the fin on the temperature distribution of both thin and thick sections of the fin are investigated. It is believed that the obtained results will facilitate the design and performance evaluation of SRC annular fins.
Pectoral fin contact as a mechanism for social bonding among dolphins
Dudzinski, Kathleen; Ribic, Christine
2017-01-01
Bottlenose dolphins are large-brained social mammals residing in a fission-fusion society with relationships that are established and maintained over decades. We examined a decade-long data set of inter-individual pectoral fin contact exchanges to better understand how dolphins share information via tactile contact. Sex and age are significant factors in pectoral fin contact within non-kin dolphin dyads. Adult females shared more pectoral fin contacts with other adult females, while younger females showed no pattern of contact. Males shared more pectoral fin contacts with other males as juveniles and as adults, but showed no difference in the number of touches versus rubs as pectoral fin contacts with other males. Whether in the role of initiator as rubber or initiator as rubbee, male dolphins again preferred other males. These results support the notion that dolphins, especially male dolphins, might use pectoral fin contact as one tool in their repertoire for social bonding to establish, maintain and manage their inter-individual relationships. Additionally, it is also likely that the exchange of pectoral fin contact is developed and refined as individuals age, mature socially, and establish their place within a fission-fusion society.
Seasonal and geographical patterns of fin whale song in the western North Atlantic Ocean.
Morano, Janelle L; Salisbury, Daniel P; Rice, Aaron N; Conklin, Karah L; Falk, Keri L; Clark, Christopher W
2012-08-01
Male fin whales, Balaenoptera physalus, produce a song consisting of 20 Hz notes at regularly spaced time intervals. Previous studies identified regional differences in fin whale internote intervals (INI), but seasonal changes within populations have not been closely examined. To understand the patterns of fin whale song in the western North Atlantic, the seasonal abundance and acoustic features of fin whale song are measured from two years of archival passive acoustic recordings at two representative locations: Massachusetts Bay and New York Bight. Fin whale 20 Hz notes are detected on 99% of recorded days. In both regions, INI varies significantly throughout the year as two distinct periods: a "short-INI" season in September-January (9.6 s) and a "long-INI" season in March-May (15.1 s). February and June-August are transitional-INI months, with higher variability. Note abundance decreases with increasing INI, where note abundance is significantly lower in April-August than in September-January. Short-INI and high note abundance correspond to the fin whale reproductive season. The temporal variability of INI may be a mechanism by which fin whale individuals encode and communicate a variety of behaviorally relevant information.
Age estimation of burbot using pectoral fin rays, brachiostegal rays, and otoliths
Klein, Zachary B.; Terrazas, Marc M.; Quist, Michael C.
2014-01-01
Throughout much of its native distribution, burbot (Lota lota) is a species of conservation concern. Understanding dynamic rate functions is critical for the effective management of sensitive burbot populations, which necessitates accurate and precise age estimates. Managing sensitive burbot populations requires an accurate and precise non-lethal alternative. In an effort to identify a non-lethal ageing structure, we compared the precision of age estimates obtained from otoliths, pectoral fin rays, dorsal fin rays and branchiostegal rays from 208 burbot collected from the Green River drainage, Wyoming. Additionally, we compared the accuracy of age estimates from pectoral fin rays, dorsal fin rays and branchiostegal rays to those of otoliths. Dorsal fin rays were immediately deemed a poor ageing structure and removed from further analysis. Age-bias plots of consensus ages derived from branchiostegal rays and pectoral fin rays were appreciably different from those obtained from otoliths. Exact agreement between readers and reader confidence was highest for otoliths and lowest for branchiostegal rays. Age-bias plots indicated that age estimates obtained from branchiostegal rays and pectoral fin rays were substantially different from age estimates obtained from otoliths. Our results indicate that otoliths provide the most precise age estimates for burbot.
Rolland-Lagan, Anne-Gaëlle; Paquette, Mathieu; Tweedle, Valerie; Akimenko, Marie-Andrée
2012-03-01
The fact that some organisms are able to regenerate organs of the correct shape and size following amputation is particularly fascinating, but the mechanism by which this occurs remains poorly understood. The zebrafish (Danio rerio) caudal fin has emerged as a model system for the study of bone development and regeneration. The fin comprises 16 to 18 bony rays, each containing multiple joints along its proximodistal axis that give rise to segments. Experimental observations on fin ray growth, regeneration and joint formation have been described, but no unified theory has yet been put forward to explain how growth and joint patterns are controlled. We present a model for the control of fin ray growth during development and regeneration, integrated with a model for joint pattern formation, which is in agreement with published, as well as new, experimental data. We propose that fin ray growth and joint patterning are coordinated through the interaction of three morphogens. When the model is extended to incorporate multiple rays across the fin, it also accounts for how the caudal fin acquires its shape during development, and regains its correct size and shape following amputation.
NASA Astrophysics Data System (ADS)
Arslanturk, Cihat
2011-02-01
Although tapered fins transfer more rate of heat per unit volume, they are not found in every practical application because of the difficulty in manufacturing and fabrications. Therefore, there is a scope to modify the geometry of a constant thickness fin in view of the less difficulty in manufacturing and fabrication as well as betterment of heat transfer rate per unit volume of the fin material. For the better utilization of fin material, it is proposed a modified geometry of new fin with a step change in thickness (SF) in the literature. In the present paper, the homotopy perturbation method has been used to evaluate the temperature distribution within the straight radiating fins with a step change in thickness and variable thermal conductivity. The temperature profile has an abrupt change in the temperature gradient where the step change in thickness occurs and thermal conductivity parameter describing the variation of thermal conductivity has an important role on the temperature profile and the heat transfer rate. The optimum geometry which maximizes the heat transfer rate for a given fin volume has been found. The derived condition of optimality gives an open choice to the designer.
Pernisova, Marketa; Prat, Tomas; Grones, Peter; Harustiakova, Danka; Matonohova, Martina; Spichal, Lukas; Nodzynski, Tomasz; Friml, Jiri; Hejatko, Jan
2016-10-01
Redirection of intercellular auxin fluxes via relocalization of the PIN-FORMED 3 (PIN3) and PIN7 auxin efflux carriers has been suggested to be necessary for the root gravitropic response. Cytokinins have also been proposed to play a role in controlling root gravitropism, but conclusive evidence is lacking. We present a detailed study of the dynamics of root bending early after gravistimulation, which revealed a delayed gravitropic response in transgenic lines with depleted endogenous cytokinins (Pro35S:AtCKX) and cytokinin signaling mutants. Pro35S:AtCKX lines, as well as a cytokinin receptor mutant ahk3, showed aberrations in the auxin response distribution in columella cells consistent with defects in the auxin transport machinery. Using in vivo real-time imaging of PIN3-GFP and PIN7-GFP in AtCKX3 overexpression and ahk3 backgrounds, we observed wild-type-like relocalization of PIN proteins in the columella early after gravistimulation, with gravity-induced relocalization of PIN7 faster than that of PIN3. Nonetheless, the cellular distribution of PIN3 and PIN7 and expression of PIN7 and the auxin influx carrier AUX1 was affected in AtCKX overexpression lines. Based on the retained cytokinin sensitivity in pin3 pin4 pin7 mutant, we propose the AUX1-mediated auxin transport rather than columella-located PIN proteins as a target of endogenous cytokinins in the control of root gravitropism. © 2016 The Authors. New Phytologist © 2016 New Phytologist Trust.
Thorn, M W; Morbey, Y E
2016-02-01
This study examines whether the anal fin undergoes secondary sexual development similar to other reproductive traits in salmonids. This hypothesis was tested by comparing the anal-fin size of female kokanee salmon Oncorhynchus nerka that were in the early and late stages of sexual development. Females in an advanced stage of maturation had significantly larger anal fins relative to females in an early state of maturation (+4-7%), indicating that the anal fin undergoes secondary sexual development. The magnitude of this secondary growth was comparable with snout length (+9-10%), which is known to undergo secondary sexual development in female salmonids. When morphological trait dimensions were compared between the sexes, the anal fin was the only morphological trait found to have a female-biased sexual size dimorphism. This is the first study to show that the anal fin of female salmonids undergoes secondary sexual development. © 2015 The Fisheries Society of the British Isles.
Fgf16 is essential for pectoral fin bud formation in zebrafish
DOE Office of Scientific and Technical Information (OSTI.GOV)
Nomura, Ryohei; Kamei, Eriko; Hotta, Yuuhei
2006-08-18
Zebrafish pectoral fin bud formation is an excellent model for studying morphogenesis. Fibroblast growth factors (Fgfs) and sonic hedgehog (shh) are essential for pectoral fin bud formation. We found that Fgf16 was expressed in the apical ectodermal ridge (AER) of fin buds. A knockdown of Fgf16 function resulted in no fin bud outgrowth. Fgf16 is required for cell proliferation and differentiation in the mesenchyme and the AER of the fin buds, respectively. Fgf16 functions downstream of Fgf10, a mesenchymal factor, signaling to induce the expression of Fgf4 and Fgf8 in the AER. Fgf16 in the AER and shh in themore » zone of polarizing activity (ZPA) interact to induce and/or maintain each other's expression. These findings have revealed that Fgf16, a newly identified AER factor, plays a crucial role in pectoral fin bud outgrowth by mediating the interactions of AER-mesenchyme and AER-ZPA.« less
Formation of a Ge-rich Si1-x Ge x (x > 0.9) fin epitaxial layer condensed by dry oxidation
NASA Astrophysics Data System (ADS)
Jang, Hyunchul; Kim, Byongju; Koo, Sangmo; Ko, Dae-Hong
2017-11-01
We have selectively grown an epitaxial Si0.35Ge0.65 fin layer in a 65 nm oxide trench pattern array and formed a Ge-rich Si1-x Ge x (x > 0.9) fin layer with condensed Ge using dry oxidation. During oxidation of the SiGe fin structure, we found that the compressive strain of the condensed SiGe layer was increased by about 1.3% while Ge was efficiently condensed due to a two-dimensional oxidation reaction. In this paper, we discussed in detail the diffusion during the two-dimensional condensation reaction as well as the asymmetric biaxial strain of the SiGe fin before and after oxidation using a reciprocal space mapping measurement. The application of dry oxidation on selectively grown SiGe fin layer can be an effective method for increasing hole mobility of SiGe fin with increased Ge content and self-induced compressive strain.
A Novel Approach to Model the Air-Side Heat Transfer in Microchannel Condensers
NASA Astrophysics Data System (ADS)
Martínez-Ballester, S.; Corberán, José-M.; Gonzálvez-Maciá, J.
2012-11-01
The work presents a model (Fin1D×3) for microchannel condensers and gas coolers. The paper focusses on the description of the novel approach employed to model the air-side heat transfer. The model applies a segment-by-segment discretization to the heat exchanger adding, in each segment, a specific bi-dimensional grid to the air flow and fin wall. Given this discretization, the fin theory is applied by using a continuous piecewise function for the fin wall temperature. It allows taking into account implicitly the heat conduction between tubes along the fin, and the unmixed air influence on the heat capacity. The model has been validated against experimental data resulting in predicted capacity errors within ± 5%. Differences on prediction results and computational cost were studied and compared with the previous authors' model (Fin2D) and with other simplified model. Simulation time of the proposed model was reduced one order of magnitude respect the Fin2D's time retaining its same accuracy.
Analysis of selected data from the triservice missile data base
NASA Technical Reports Server (NTRS)
Allen, Jerry M.; Shaw, David S.; Sawyer, Wallace C.
1989-01-01
An extremely large, systematic, axisymmetric-body/tail-fin data base has been gathered through tests of an innovative missile model design which is described herein. These data were originally obtained for incorporation into a missile aerodynamics code based on engineering methods (Program MISSILE3), but these data are also valuable as diagnostic test cases for developing computational methods because of the individual-fin data included in the data base. Detailed analyses of four sample cases from these data are presented to illustrate interesting individual-fin force and moment trends. These samples quantitatively show how bow shock, fin orientation, fin deflection, and body vortices can produce strong, unusual, and computationally challenging effects on individual fin loads. Flow-visualization photographs are examined to provide physical insight into the cause of these effects.
Manoogian, Sarah; Lee, Adam K; Widmaier, James C
2017-08-01
No studies have assessed the effects of parameters associated with insertion temperature in modern self-drilling external fixation pins. The current study assessed how varying the presence of irrigation, insertion speed, and force impacted the insertion temperatures of 2 types of standard and self-drilling external fixation half pins. Seventy tests were conducted with 10 trials for 4 conditions on self-drilling pins, and 3 conditions for standard pins. Each test used a thermocouple inside the pin to measure temperature rise during insertion. Adding irrigation to the standard pin insertion significantly lowered the maximum temperature (P <0.001). Lowering the applied force for the standard pin did not have a significant change in temperature rise. Applying irrigation during the self-drilling pin tests dropped average rise in temperature from 151.3 ± 21.6°C to 124.1 ± 15.3°C (P = 0.005). When the self-drilling pin insertion was decreased considerably from 360 to 60 rpm, the temperature decreased significantly from 151.3 ± 21.6°C to 109.6 ± 14.0°C (P <0.001). When the force applied increased significantly, the corresponding self-drilling pin temperature increase was not significant. The standard pin had lower peak temperatures than the self-drilling pin for all conditions. Moreover, slowing down the insertion speed and adding irrigation helped mitigate the temperature increase of both pin types during insertion.
Wang, Shengguang; Zhang, Hua; Zhu, Jianquan; Li, Chenguang; Zhu, Jinfang; Shi, Bowen; Zhang, Bin
2017-01-01
PinX1 has been identified as a suppressor of telomerase enzymatic activity. However, the tumour-suppressive roles of PinX1 in different types of human cancers are unclear. PinX1 expression status and its correlation with clinicopathological features in non-small-cell lung cancer (NSCLC) have not been investigated. Accordingly, in this study, we aimed to evaluate the roles of PinX1 in NSCLC. PinX1 expression status was examined by immunohistochemistry using tissue microarray from a total of 158 patients. Correlations among PinX1 expression, clinicopathological variables, and patient survival were analysed. Furthermore, we overexpressed PinX1 in NSCLC cells and tested telomerase activity using real-time quantitative telomeric repeat amplification protocol (qTRAP) assays. Proliferation and migration of NSCLC cells were examined using the MTS method, wound healing assays, and transwell assays, respectively. Our results showed that negative PinX1 expression was associated with a poor prognosis in NSCLC. Sex, smoking status, lymph gland status, subcarinal lymph node status, pathological stage, and PinX1 expression were related to survival. PinX1 was not an independent prognostic factor in NSCLC. PinX1 overexpression inhibited proliferation and migration in NSCLC cells by suppressing telomerase activity. Our findings suggested that PinX1 could be a potential tumour suppressor in NSCLC and that loss of PinX1 promoted NSCLC progression. PMID:28815183
NASA Astrophysics Data System (ADS)
Kamal Babu, Karupannan; Panneerselvam, Kavan; Sathiya, Paulraj; Noorul Haq, Abdul Haq; Sundarrajan, Srinivasan; Mastanaiah, Potta; Srinivasa Murthy, Chunduri Venkata
2018-02-01
Friction stir welding (FSW) process was conducted on cryorolled (CR) AA2219 plate using different tool pin profiles such as cylindrical pin, threaded cylindrical pin, square pin and hexagonal pin profiles. The FSW was carried out with pairs of 6 mm thick CR aluminium plates with different tool pin profiles. The different tool pin profile weld portions' behaviors like mechanical (tensile strength, impact and hardness) and metallurgical characteristics were analyzed. The results of the mechanical analysis revealed that the joint made by the hexagonal pin tool had good strength compared to other pin profiles. This was due to the pulsating action and material flow of the tool resulting in dynamic recrystallization in the weld zone. This was confirmed by the ultra fine grain structure formation in Weld Nugget (WN) of hexagonal pin tool joint with a higher percentage of precipitate dissolution. The fractograph of the hexagonal tool pin weld portion confirmed the finer dimple structure morphology without having any interior defect compared to other tool pin profiles. The lowest weld joint strength was obtained from cylindrical pin profile weld joint due to insufficient material flow during welding. The Transmission Electron Microscope and EDX analysis showed the dissolution of the metastable θ″, θ' (Al2Cu) partial precipitates in the WN and proved the influence of metastable precipitates on enhancement of mechanical behavior of weld. The XRD results also confirmed the Al2Cu precipitation dissolution in the weld zone.
Walker; Westneat
1997-01-01
Labriform, or pectoral fin, propulsion is the primary swimming mode for many fishes, even at high relative speeds. Although kinematic data are critical for evaluating hydrodynamic models of propulsion, these data are largely lacking for labriform swimmers, especially for species that employ an exclusively labriform mode across a broad range of speeds. We present data on pectoral fin locomotion in Gomphosus varius (Labridae), a tropical coral reef fish that uses a lift-based mechanism to fly under water at sustained speeds of 16 total body lengths s-1 (TL s-1). Lateral- and dorsal-view video images of three fish swimming in a flow tank at 14 TL s-1 were recorded at 60 Hz. From the two views, we reconstructed the three-dimensional motion of the center of mass, the fin tip and two fin chords for multiple fin beats of each fish at each of four speeds. In G. varius, the fin oscillates largely up and down: the stroke plane is tilted by approximately 20 ° from the vertical. Both frequency and the area swept by the pectoral fins increase with swimming speed. Interestingly, there are individual differences in how this area increases. Relative to the fish, the fin tip in lateral view moves along the path of a thin, inclined figure-of-eight. Relative to a stationary observer, the fin tip traces a sawtooth pattern, but the teeth are recumbent (indicating net backwards movement) only at the slowest speeds. Distal fin chords pitch nose downward during the downstroke and nose upward during the upstroke. Hydrodynamic angles of attack are largely positive during the downstroke and negative during the upstroke. The geometry of the fin and incident flow suggests that the fin is generating lift with large upward and small forward components during the downstroke. The negative incident angles during the upstroke suggest that the fin is generating largely thrust during the upstroke. In general, the large thrust is combined with a downward force during the upstroke, but the net backwards motion of the fin at slow speeds generates a small upward component during slow swimming. Both the alternating sign of the hydrodynamic angle of attack and the observed reduced frequencies suggest that unsteady effects are important in G. varius aquatic flight, especially at low speeds. This study provides a framework for the comparison of aquatic flight by fishes with aerial flight by birds, bats and insects.
Fin Ray Stiffness and Fin Morphology Control Ribbon-Fin-Based Propulsion.
Liu, Hanlin; Taylor, Bevan; Curet, Oscar M
2017-06-01
Ribbon-fin-based propulsion has rich locomotor capabilities that can enhance the mobility and performance of underwater vehicles navigating in complex environments. Bony fishes using this type of propulsion send one or multiple traveling waves along an elongated fin with the actuation of highly flexible rays that are interconnected by an elastic membrane. In this work, we study how the use of flexible rays and different morphology can affect the performance of ribbon-fin propulsion. We developed a physical model composed of 15 rays that are interconnected with an elastic membrane. We tested four different ray flexural stiffness and four aspect ratios. The robotic model was tested in a low-turbulence flume under two flow conditions ([Formula: see text] wavelength/s). In two experimental sets, we measured fin kinematics, net surge forces, and power consumption. Using these data, we perform a thrust and power analysis of the undulating fin. We present the thrust coefficient, power coefficient, and propulsive efficiency. We find that the thrust generation was linear with the enclosed area swept by the fin, and square of the relative velocity between the incoming flow and traveling wave. The thrust coefficient levels off around 0.5. In addition, for our parameter range, we find that the power consumption scales by the cube of the effective tangential velocity of the rays [Formula: see text] (A is the amplitude of the ray oscillating motion, and [Formula: see text] is the angular velocity). We show that a decay in stiffness decreases both thrust production and power consumption. However, for rays with high flexural stiffness, the difference in thrust compared with rigid rays is minimal. Moreover, our results show that flexible rays can improve the propulsive efficiency compared with a rigid counterpart. Finally, we find that the morphology of ribbon fin affects its propulsive efficiency. For the aspect ratio considered in our experiments, [Formula: see text] was the most efficient compared with [Formula: see text]. Our results suggest that there could be an optimal morphology for a given ribbon fin kinematics. Therefore, both natural swimmers and underwater vehicles using ribbon-fin-based propulsion can take advantage of flexible rays and optimal aspect ratio to improve propulsive performance.
Haga, Ken; Sakai, Tatsuya
2012-10-01
Auxin efflux carrier PIN-FORMED (PIN) proteins are thought to have central roles in regulating asymmetrical auxin translocation during tropic responses, including gravitropism and phototropism, in plants. Although PIN3 is known to be involved in phototropism in Arabidopsis (Arabidopsis thaliana), no severe defects of phototropism in any of the pin mutants have been reported. We show here that the pulse-induced, first positive phototropism is impaired partially in pin1, pin3, and pin7 single mutants, and severely in triple mutants. In contrast, such impairment was not observed in continuous-light-induced second positive phototropism. Analysis with an auxin-reporter gene demonstrated that PIN3-mediated auxin gradients participate in pulse-induced phototropism but not in continuous-light-induced phototropism. Similar functional separation was also applicable to PINOID, a regulator of PIN localization. Our results strongly suggest the existence of functionally distinct mechanisms i.e. a PIN-dependent mechanism in which transient stimulation is sufficient to induce phototropism, and a PIN-independent mechanism that requires continuous stimulation and does not operate in the former phototropism process. Although a previous study has proposed that blue-light photoreceptors, the phototropins, control PIN localization through the transcriptional down-regulation of PINOID, we could not detect this blue-light-dependent down-regulation event, suggesting that other as yet unknown mechanisms are involved in phototropin-mediated phototropic responses.
Haga, Ken; Sakai, Tatsuya
2012-01-01
Auxin efflux carrier PIN-FORMED (PIN) proteins are thought to have central roles in regulating asymmetrical auxin translocation during tropic responses, including gravitropism and phototropism, in plants. Although PIN3 is known to be involved in phototropism in Arabidopsis (Arabidopsis thaliana), no severe defects of phototropism in any of the pin mutants have been reported. We show here that the pulse-induced, first positive phototropism is impaired partially in pin1, pin3, and pin7 single mutants, and severely in triple mutants. In contrast, such impairment was not observed in continuous-light-induced second positive phototropism. Analysis with an auxin-reporter gene demonstrated that PIN3-mediated auxin gradients participate in pulse-induced phototropism but not in continuous-light-induced phototropism. Similar functional separation was also applicable to PINOID, a regulator of PIN localization. Our results strongly suggest the existence of functionally distinct mechanisms i.e. a PIN-dependent mechanism in which transient stimulation is sufficient to induce phototropism, and a PIN-independent mechanism that requires continuous stimulation and does not operate in the former phototropism process. Although a previous study has proposed that blue-light photoreceptors, the phototropins, control PIN localization through the transcriptional down-regulation of PINOID, we could not detect this blue-light-dependent down-regulation event, suggesting that other as yet unknown mechanisms are involved in phototropin-mediated phototropic responses. PMID:22843667
Spring loaded locator pin assembly
Groll, Todd A.; White, James P.
1998-01-01
This invention deals with spring loaded locator pins. Locator pins are sometimes referred to as captured pins. This is a mechanism which locks two items together with the pin that is spring loaded so that it drops into a locator hole on the work piece.
Method and apparatus for enhancing vortex pinning by conformal crystal arrays
Janko, Boldizsar; Reichhardt, Cynthia; Reichhardt, Charles; Ray, Dipanjan
2015-07-14
Disclosed is a method and apparatus for strongly enhancing vortex pinning by conformal crystal arrays. The conformal crystal array is constructed by a conformal transformation of a hexagonal lattice, producing a non-uniform structure with a gradient where the local six-fold coordination of the pinning sites is preserved, and with an arching effect. The conformal pinning arrays produce significantly enhanced vortex pinning over a much wider range of field than that found for other vortex pinning geometries with an equivalent number of vortex pinning sites, such as random, square, and triangular.
Improved protease stability of the antimicrobial peptide Pin2 substituted with D-amino acids.
Carmona, G; Rodriguez, A; Juarez, D; Corzo, G; Villegas, E
2013-08-01
Cationic antimicrobial peptides (AMPs) have attracted a great interest as novel class of antibiotics that might help in the treatment of infectious diseases caused by pathogenic bacteria. However, some AMPs with high antimicrobial activities are also highly hemolytic and subject to proteolytic degradation from human and bacterial proteases that limit their pharmaceutical uses. In this work a D-diastereomer of Pandinin 2, D-Pin2, was constructed to observe if it maintained antimicrobial activity in the same range as the parental one, but with the purpose of reducing its hemolytic activity to human erythrocytes and improving its ability to resist proteolytic cleavage. Although, the hydrophobic and secondary structure characteristics of L- and D-Pin2 were to some extent similar, an important reduction in D-Pin2 hemolytic activity (30-40 %) was achieved compared to that of L-Pin2 over human erythrocytes. Furthermore, D-Pin2 had an antimicrobial activity with a MIC value of 12.5 μM towards Staphylococcus aureus, Escherichia coli, Streptococcus agalactiae and two strains of Pseudomonas aeruginosa in agar diffusion assays, but it was half less potent than that of L-Pin2. Nevertheless, the antimicrobial activity of D-Pin2 was equally effective as that of L-Pin2 in microdilution assays. Yet, when D- and L-Pin2 were incubated with trypsin, elastase and whole human serum, only D-Pin2 kept its antimicrobial activity towards all bacteria, but in diluted human serum, L- and D-Pin2 maintained similar peptide stability. Finally, when L- and D-Pin2 were incubated with proteases from P. aeruginosa DFU3 culture, a clinical isolated strain, D-Pin2 kept its antibiotic activity while L-Pin2 was not effective.
Development of a whole-organism model to screen new compounds for sun protection.
Wang, Yun-Hsin; Wen, Chi-Chung; Yang, Zhi-Shiang; Cheng, Chien-Chung; Tsai, Jen-Ning; Ku, Chia-Chen; Wu, Hsin-Ju; Chen, Yau-Hung
2009-01-01
We used zebrafish as a whole-organism model to screen new compounds for sun protection activity. First of all, we designed a series of UVB exposure experiments and recorded the phenotypic changes of zebrafish embryos. Results showed that 100 mJ/cm(2) of UVB given six times separated by 30 min intervals is the best condition. Fin malformation (reduced and/or absent fin) phenotypes are the most evident consequences after exposure to UVB. Each fin was affected by UVB, including pelvic, ventral, caudal, and dorsal fin, but pelvic fin seemed to be the most sensitive target after UVB exposure. We furthermore carried out "prevention" and "treatment" experiments using green tea extract and/or (-)-epigallocatechin (EGCG) to test this whole-organism model by observing the morphological changes of all fins (especially pelvic fin) after UVB exposure. Effects of UVB, green tea extract and EGCG on fin development were assessed using the Kaplan-Meier analysis, log-rank test and Cox proportional hazards regression. Results showed that a zebrafish pelvic fin in the UVB + green tea (treatment) group is 5.51 (range from 2.39 to 14.90) times, one in the UVB + green tea (prevention) group is 7.04 (range from 3.11 to 18.92) times, and one in the 25 ppm of EGCG (prevention) group is 22.19 (range from 9.40 to 61.50) times more likely to return to normal fin than one in the UVB only group. On the basis of these observations, we believe this model is effective for screening the higher stability and lower toxicity of new compounds, such as small chemicals which are derivative from EGCG or other dietary agents for sun protection.
Hette Tronquart, Nicolas; Mazeas, Laurent; Reuilly-Manenti, Liana; Zahm, Amandine; Belliard, Jérôme
2012-07-30
Dorsal white muscle is the standard tissue analysed in fish trophic studies using stable isotope analyses. However, sampling white muscle often implies the sacrifice of fish. Thus, we examined whether the non-lethal sampling of fin tissue can substitute muscle sampling in food web studies. Analysing muscle and fin δ(15)N and δ(13)C values of 466 European freshwater fish (14 species) with an elemental analyser coupled with an isotope ratio mass spectrometer, we compared the isotope values of the two tissues. Correlations between fin and muscle isotope ratios were examined for all fish together and specifically for 12 species. We further proposed four methods of assessing muscle from fin isotope ratios and estimated the errors made using these muscle surrogates. Despite significant differences between isotope values of the two tissues, fin and muscle isotopic signals are strongly correlated. Muscle values, estimated with raw fin isotope ratios (1st method), induce an error of ca. 1‰ for both isotopes. In comparison, specific (2nd method) or general (3rd method) correlations provide meaningful corrections of fin isotope ratios (errors <0.6‰). On the other hand, relationships, established for Australian tropical fish, only give poor muscle estimates (errors >0.8‰). There is little chance that a global model can be created. However, the 2nd and 3rd methods of estimating muscle values from fin isotope ratios should provide an acceptable level of error for the studies of European freshwater food web. We thus recommend that future studies use fin tissue as a non-lethal surrogate for muscle. Copyright © 2012 John Wiley & Sons, Ltd.
Alignment Pins for Assembling and Disassembling Structures
NASA Technical Reports Server (NTRS)
Campbell, Oliver C.
2008-01-01
Simple, easy-to-use, highly effective tooling has been devised for maintaining alignment of bolt holes in mating structures during assembly and disassembly of the structures. The tooling was originally used during removal of a body flap from the space shuttle Atlantis, in which misalignments during removal of the last few bolts could cause the bolts to bind in their holes. By suitably modifying the dimensions of the tooling components, the basic design of the tooling can readily be adapted to other structures that must be maintained in alignment. The tooling includes tapered, internally threaded alignment pins designed to fit in the bolt holes in one of the mating structures, plus a draw bolt and a cup that are used to install or remove each alignment pin. In preparation for disassembly of two mating structures, external supports are provided to prevent unintended movement of the structures. During disassembly of the structures, as each bolt that joins the structures is removed, an alignment pin is installed in its place. Once all the bolts have been removed and replaced with pins, the pins maintain alignment as the structures are gently pushed or pulled apart on the supports. In assembling the two structures, one reverses the procedure described above: pins are installed in the bolt holes, the structures are pulled or pushed together on the supports, then the pins are removed and replaced with bolts. The figure depicts the tooling and its use. To install an alignment pin in a bolt hole in a structural panel, the tapered end of the pin is inserted from one side of the panel, the cup is placed over the pin on the opposite side of the panel, the draw bolt is inserted through the cup and threaded into the pin, the draw bolt is tightened to pull the pin until the pin is seated firmly in the hole, then the draw bolt and cup are removed, leaving the pin in place. To remove an alignment pin, the cup is placed over the pin on the first-mentioned side of the panel, the draw bolt is inserted through the cup and threaded into the pin, then the draw bolt is tightened to pull the pin out of the hole.
Spring loaded locator pin assembly
Groll, T.A.; White, J.P.
1998-03-03
This invention deals with spring loaded locator pins. Locator pins are sometimes referred to as captured pins. This is a mechanism which locks two items together with the pin that is spring loaded so that it drops into a locator hole on the work piece. 5 figs.
Bramblett, Richard L.; Preskitt, Charles A.
1987-03-03
Systems and methods for inspection of nuclear fuel pins to determine fiss loading and uniformity. The system includes infeed mechanisms which stockpile, identify and install nuclear fuel pins into an irradiator. The irradiator provides extended activation times using an approximately cylindrical arrangement of numerous fuel pins. The fuel pins can be arranged in a magazine which is rotated about a longitudinal axis of rotation. A source of activating radiation is positioned equidistant from the fuel pins along the longitudinal axis of rotation. The source of activating radiation is preferably oscillated along the axis to uniformly activate the fuel pins. A detector is provided downstream of the irradiator. The detector uses a plurality of detector elements arranged in an axial array. Each detector element inspects a segment of the fuel pin. The activated fuel pin being inspected in the detector is oscillated repeatedly over a distance equal to the spacing between adjacent detector elements, thereby multiplying the effective time available for detecting radiation emissions from the activated fuel pin.
NASA Technical Reports Server (NTRS)
Ding, R. Jeffrey; Oelgoetz, Peter A.
1999-01-01
The "Auto-Adjustable Pin Tool for Friction Stir Welding", was developed at The Marshall Space Flight Center to address process deficiencies unique to the FSW process. The auto-adjustable pin tool, also called the retractable pin-tool (R.PT) automatically withdraws the welding probe of the pin-tool into the pin-tool's shoulder. The primary function of the auto-adjustable pin-tool is to allow for keyhole closeout, necessary for circumferential welding and localized weld repair, and, automated pin-length adjustment for the welding of tapered material thickness. An overview of the RPT hardware is presented. The paper follows with studies conducted using the RPT. The RPT was used to simulate two capabilities; welding tapered material thickness and closing out the keyhole in a circumferential weld. The retracted pin-tool regions in aluminum- lithium 2195 friction stir weldments were studied through mechanical property testing and metallurgical sectioning. Correlation's can be =de between retractable pin-tool programmed parameters, process parameters, microstructure, and resulting weld quality.
NASA Astrophysics Data System (ADS)
Wolverton, Chris
As nonmotile organisms, plants rely on differential growth responses to maximize exposure to the resources necessary for growth and reproduction. One of the primary environmental cues causing differential growth in roots is gravity, which is thought to be sensed predominately in the root cap. This gravity perception event is thought to be transduced into information in the form of an auxin gradient across the cap and propagating basipetally toward the elongation zone. The discovery of several families of auxin efflux and influx carriers has provided significant insight into the mechanisms of directional auxin transport, and the identification of mutants in the genes encoding these carriers provides the opportunity to test the roles of these transporters in plant gravitropism. In this study, we report the results of a systematic, high-resolution study of the kinetics of root gravitropism of mutants in the PIN family of auxin efflux carriers. Based on reported expression and localization patterns, we predicted mutations in PIN2, PIN3, PIN4, and PIN7 to cause the greatest reduction in root gravitropism. While pin2 mutants showed severe gravitropic deficiencies in roots as reported previously, several alleles of pin3, pin4 and pin7 remained strongly gravitropic. PIN3 has been localized to the central columella cells, the purported gravisensing cells in the root, and shown to rapidly relocate to the lower flank of the columella cells upon gravistimulation, suggesting an early role in auxin gradient formation. Mutant alleles of PIN3 showed an early delay in response, with just 7 deg of curvature in the first hour compared to approximately 15 deg h-1 in wild-type, but their rate of curvature recovered to near wild-type levels over the ensuing 3 h. Pin3 mutants also showed a slower overall growth rate (124 µm h-1 ), elongating at approximately half the rate of wild-type roots (240 µm h-1 ). PIN4 has been localized to the quiescent center in the root, where it presumably plays a role in efflux to the columella. Pin4 mutants showed no deficiencies in gravitropism, in fact responding at a greater rate than wild-type roots over the first hour (22 deg h-1 ). PIN7 has been localized to the vascular tissue of the elongation zone and to the central columella. Like pin4 mutants, pin7 mutants did not show a significantly reduced gravitropic response relative to wild-type roots. Interestingly, roots of pin3pin7 double mutants showed curvature and growth rates similar to pin7 single mutants and wild-type roots, suggesting a genetic interaction between PIN3 and PIN7 in this pathway. These results suggest a significant degree of redundancy in the regulation of directional auxin transport and perhaps in the gravity signaling pathway in roots in general.
NASA Astrophysics Data System (ADS)
Zhang, Xiangyang; Li, Yong; Van Hoa, Suong; Xiao, Jun; Chu, Qiyi
2018-02-01
Skin/stiffener debonding has been a longstanding concern for the users of stiffened composite panels in long-term service. Z-pinning technology is an emerging solution to reinforce the composite assembly joints. This work experimentally characterizes the progressive debonding of Z-pinned skin/stiffener interface with the skin under static bend loading. The three-stage failure process is identified as: flange edge debonding, pin/laminate debonding, and ultimate structural failure. Three different distribution patterns were compared in terms of the static debonding properties revealed the affirmative fact that locating pins in high normal stress regions, that is close to the flange edges in skin/stiffener structures, is more beneficial to utilize the full potential of Z-pinning reinforcement. The unit strip FE model was developed and demonstrated effective to analysis the effect of Z-pin distribution on the ultimate debond load. On the other hand, the evolution of fatigue cracks at Z-pinned skin/flange interface was investigated with a series of displacement-controlled fatigue bending tests and microscopic observations. Results show that Z-pinning postpones crack initiations at low displacement levels, and the remarkable crack-arresting function of pins enables the structure a prolonged fatigue life. However, pins become less effective when the maximum displacement exceeds the crack initiation level due to gradually pullout of pins.
van der Borden, Arnout J; Maathuis, Patrick G M; Engels, Eefje; Rakhorst, Gerhard; van der Mei, Henny C; Busscher, Henk J; Sharma, Prashant Kumar
2007-04-01
Pin tract infections of external fixators used in orthopaedic reconstructive bone surgery are serious complications that can eventually lead to periostitis and osteomyelitis. In vitro experiments have demonstrated that bacteria adhering to stainless steel in a biofilm mode of growth detach under the influence of small electric currents, while remaining bacteria become less viable upon current application. Therefore, we have investigated whether a 100microA electric current can prevent signs of clinical infection around percutaneous pins, implanted in the tibia of goats. Three pins were inserted into the lateral right tibia of nine goats, of which one served for additional frame support. Two pins were infected with a Staphylococcus epidermidis strain of which one pin was subjected to electric current, while the other pin was used as control. Pin sites were examined daily. The wound electrical resistance decreased with worsening of the infection from a dry condition to a purulent stage. After 21 days, animals were sacrificed and the pins taken out. Infection developed in 89% of the control pin sites, whereas only 11% of the pin sites in the current group showed infection. These results show that infection of percutaneous pin sites of external fixators in reconstructive bone surgery can be prevented by the application of a small DC electric current.
Wear-Induced Changes in FSW Tool Pin Profile: Effect of Process Parameters
NASA Astrophysics Data System (ADS)
Sahlot, Pankaj; Jha, Kaushal; Dey, G. K.; Arora, Amit
2018-06-01
Friction stir welding (FSW) of high melting point metallic (HMPM) materials has limited application due to tool wear and relatively short tool life. Tool wear changes the profile of the tool pin and adversely affects weld properties. A quantitative understanding of tool wear and tool pin profile is crucial to develop the process for joining of HMPM materials. Here we present a quantitative wear study of H13 steel tool pin profile for FSW of CuCrZr alloy. The tool pin profile is analyzed at multiple traverse distances for welding with various tool rotational and traverse speeds. The results indicate that measured wear depth is small near the pin root and significantly increases towards the tip. Near the pin tip, wear depth increases with increase in tool rotational speed. However, change in wear depth near the pin root is minimal. Wear depth also increases with decrease in tool traverse speeds. Tool pin wear from the bottom results in pin length reduction, which is greater for higher tool rotational speeds, and longer traverse distances. The pin profile changes due to wear and result in root defect for long traverse distance. This quantitative understanding of tool wear would be helpful to estimate tool wear, optimize process parameters, and tool pin shape during FSW of HMPM materials.
Effects of anisotropic conduction and heat pipe interaction on minimum mass space radiators
NASA Technical Reports Server (NTRS)
Baker, Karl W.; Lund, Kurt O.
1991-01-01
Equations are formulated for the two dimensional, anisotropic conduction of heat in space radiator fins. The transverse temperature field was obtained by the integral method, and the axial field by numerical integration. A shape factor, defined for the axial boundary condition, simplifies the analysis and renders the results applicable to general heat pipe/conduction fin interface designs. The thermal results are summarized in terms of the fin efficiency, a radiation/axial conductance number, and a transverse conductance surface Biot number. These relations, together with those for mass distribution between fins and heat pipes, were used in predicting the minimum radiator mass for fixed thermal properties and fin efficiency. This mass is found to decrease monotonically with increasing fin conductivity. Sensitivities of the minimum mass designs to the problem parameters are determined.
Performance of a three-dimensional Navier-Stokes code on CYBER 205 for high-speed juncture flows
NASA Technical Reports Server (NTRS)
Lakshmanan, B.; Tiwari, S. N.
1987-01-01
A vectorized 3D Navier-Stokes code has been implemented on CYBER 205 for solving the supersonic laminar flow over a swept fin/flat plate junction. The code extends MacCormack's predictor-corrector finite volume scheme to a generalized coordinate system in a locally one dimensional time split fashion. A systematic parametric study is conducted to examine the effect of fin sweep on the computed flow field. Calculated results for the pressure distribution on the flat plate and fin leading edge are compared with the experimental measurements of a right angle blunt fin/flat plate junction. The decrease in the extent of the separated flow region and peak pressure on the fin leading edge, and weakening of the two reversed supersonic zones with increase in fin sweep have been clearly observed in the numerical simulation.
NASA Technical Reports Server (NTRS)
Lee, J. B.; Basford, R. C.
1957-01-01
As a continuation of an investigation of the ejection release characteristics of an internally carried MB-1 rocket in the Convair F-106A airplane, fin modifications at additional Mach numbers and simulated altitudes have been studied in the 27- by 27-inch preflight jet of the Langley Pilotless Aircraft Research Station at Wallops Island, Va. The MB-1 rocket was ejected with fins open, fins closed, fins closed with a shroud around the fins, and fins folded with a "boattail" placed in between the fins. Dynamically scaled models (0.0^956 scale) were tested at simulated altitudes of 12,000, 18,850, and 27,500 feet at subsonic Mach numbers and at 18,850, 27,500, and 40,000 feet for Mach numbers of 1-39, 1-59, and 1.98. Successful ejections can be obtained for over 10 store diameters from release point by the use of a shroud around the folded fins with the proper ejection velocity and nose-down pitching moment at release. In one case investigated it was found desirable to close off the front one-third of the bomb bay. It appeared that the fins should be opened after release and within 5 "to 6 rocket diameters if no modifications are made on the rocket. An increase in fuselage angle of attack caused higher nose-up pitch rates after release.
Effect of magnetic field on the flux pinning mechanisms in Al and SiC co-doped MgB2 superconductor
NASA Astrophysics Data System (ADS)
Kia, N. S.; Ghorbani, S. R.; Arabi, H.; Hossain, M. S. A.
2018-07-01
MgB2 superconductor samples co-doped with 0.02 wt. Al2O3 and 0-0.05 wt. SiC were studied by magnetization - magnetic field (M-H) loop measurements at different temperatures. The critical current density has been calculated by the Bean model, and the irreversibility field, Hirr, has been obtained by the Kramer method. The pinning mechanism of the co-doped sample with 2% Al and 5% SiC was investigated in particular due to its having the highest Hirr. The normalized volume pinning force f = F/Fmax as a function of reduced magnetic field h = H/Hirr has been obtained, and the pinning mechanism was studied by the Dew-Houghes model. It was found that the normal point pinning (NPP), the normal surface pinning (NSP), and the normal volume pinning (NVP) mechanisms play the main roles. The magnetic field and temperature dependence of contributions of the NPP, NSP, and NVP pinning mechanisms were obtained. The results show that the contributions of the pinning mechanisms depend on the temperature and magnetic field. From the temperature dependence of the critical current density within the collective pinning theory, it was found that both the δl pinning due to spatial fluctuations of the charge-carrier mean free path and the δTc pinning due to randomly distributed spatial variations in the transition temperature coexist at zero magnetic field in co-doped samples. Yet, the charge-carrier mean-free-path fluctuation pinning (δl) is the only important pinning mechanism at non-zero magnetic fields.
Expression of proteinase inhibitor II proteins during floral development in Solanum americanum.
Sin, Suk-Fong; Chye, Mee-Len
2004-10-01
The heterologous expression of serine proteinase inhibitor II (PIN2) proteins confers insect resistance in transgenic plants, but little is known of their endogenous roles. We have cloned two cDNAs encoding Solanum americanum PIN2 proteins, SaPIN2a and SaPIN2b. SaPIN2a is highly expressed in stem, particularly in the phloem, suggesting it could possibly regulate proteolysis in the sieve elements. When SaPIN2a was expressed in transgenic lettuce, we observed an inhibition of endogenous trypsin- and chymotrypsin-like activities. Here, we demonstrate that both SaPIN2a and SaPIN2b are expressed in floral tissues that are destined to undergo developmental programmed cell death (PCD), suggesting possible endogenous roles in inhibiting trypsin- and chymotrypsin-like activities during flower development. Northern and western blot analyses revealed that SaPIN2a and SaPIN2b mRNAs and proteins show highest expression early in floral development. In situ hybridization analysis and immunolocalization on floral sections, localized SaPIN2a and SaPIN2b mRNAs and their proteins to tissues that would apparently undergo PCD: the ovules, the stylar transmitting tissue, the stigma and the vascular bundles. Detection of PCD in floral sections was achieved using terminal deoxynucleotidyltransferase-mediated dUTP nick end labeling (TUNEL) analysis. Examination of the mid-style before, and 1 day after, pollination revealed that high expression of SaPIN2a and SaPIN2b in the style was inversely correlated with PCD.
Palovaara, Joakim; Hallberg, Henrik; Stasolla, Claudio; Luit, Bert; Hakman, Inger
2010-04-01
In seed plants, the body organization is established during embryogenesis and is uniform across gymnosperms and angiosperms, despite differences during early embryogeny. Evidence from angiosperms implicates the plant hormone auxin and its polar transport, mainly established by the PIN family of auxin efflux transporters, in the patterning of embryos. Here, PaPIN1 from Norway spruce (Picea abies [L.] Karst.), a gene widely expressed in conifer tissues and organs, was characterized and its expression and localization patterns were determined with reverse transcription polymerase chain reaction and in situ hybridization during somatic embryo development and in seedlings. PaPIN1 shares the predicted structure of other PIN proteins, but its central hydrophilic loop is longer than most PINs. In phylogenetic analyses, PaPIN1 clusters with Arabidopsis thaliana (L.) Heynh. PIN3, PIN4 and PIN7, but its expression pattern also suggests similarity to PIN1. The PaPIN1 expression signal was high in the protoderm of pre-cotyledonary embryos, but not if embryos were pre-treated with the auxin transport inhibitor N-1-naphthylphthalamic acid (NPA). This, together with a high auxin immunolocalization signal in this cell layer, suggests a role of PaPIN1 during cotyledon formation. At later stages, high PaPIN1 expression was observed in differentiating procambium, running from the tip of incipient cotyledons down through the embryo axis and to the root apical meristem (RAM), although the mode of RAM specification in conifer embryos differs from that of most angiosperms. Also, the PaPIN1 in situ signal was high in seedling root tips including root cap columella cells. The results thus suggest that PaPIN1 provides an ancient function associated with auxin transport and embryo pattern formation prior to the separation of angiosperms and gymnosperms, in spite of some morphological differences.
Zheng, Zhigang; Yang, Xiaoming; Fu, Yaping; Zhu, Longfei; Wei, Hantian; Lin, Xinchun
2017-01-01
Because of the long and unpredictable flowering period in bamboo, the molecular mechanism of bamboo flowering is unclear. Recent study showed that Arabidopsis PIN1-type parvulin 1 (Pin1At) is an important floral activator and regulates floral transition by facilitating the cis/trans isomerization of the phosphorylated Ser/Thr residues preceding proline motifs in suppressor of overexpression of CO 1 (SOC1) and agamous-like 24 (AGL24). Whether bamboo has a Pin1 homolog and whether it works in bamboo flowering are still unknown. In this study, we cloned PvPin1, a homolog of Pin1At, from Phyllostachys violascens (Bambusoideae). Bioinformatics analysis showed that PvPin1 is closely related to Pin1-like proteins in monocots. PvPin1 was widely expressed in all tested bamboo tissues, with the highest expression in young leaf and lowest in floral bud. Moreover, PvPin1 expression was high in leaves before bamboo flowering then declined during flower development. Overexpression of PvPin1 significantly delayed flowering time by downregulating SOC1 and AGL24 expression in Arabidopsis under greenhouse conditions and conferred a significantly late flowering phenotype by upregulating OsMADS56 in rice under field conditions. PvPin1 showed subcellular localization in both the nucleus and cytolemma. The 1500-bp sequence of the PvPin1 promoter was cloned, and cis-acting element prediction showed that ABRE and TGACG-motif elements, which responded to abscisic acid (ABA) and methyl jasmonate (MeJA), respectively, were characteristic of P. violascens in comparison with Arabidopsis. On promoter activity analysis, exogenous ABA and MeJA could significantly inhibit PvPin1 expression. These findings suggested that PvPin1 may be a repressor in flowering, and its delay of flowering time could be regulated by ABA and MeJA in bamboo. PMID:28951734
Zheng, Zhigang; Yang, Xiaoming; Fu, Yaping; Zhu, Longfei; Wei, Hantian; Lin, Xinchun
2017-01-01
Because of the long and unpredictable flowering period in bamboo, the molecular mechanism of bamboo flowering is unclear. Recent study showed that Arabidopsis PIN1-type parvulin 1 (Pin1At) is an important floral activator and regulates floral transition by facilitating the cis/trans isomerization of the phosphorylated Ser/Thr residues preceding proline motifs in suppressor of overexpression of CO 1 (SOC1) and agamous-like 24 (AGL24). Whether bamboo has a Pin1 homolog and whether it works in bamboo flowering are still unknown. In this study, we cloned PvPin1 , a homolog of Pin1At , from Phyllostachys violascens (Bambusoideae). Bioinformatics analysis showed that PvPin1 is closely related to Pin1-like proteins in monocots. PvPin1 was widely expressed in all tested bamboo tissues, with the highest expression in young leaf and lowest in floral bud. Moreover, PvPin1 expression was high in leaves before bamboo flowering then declined during flower development. Overexpression of PvPin1 significantly delayed flowering time by downregulating SOC1 and AGL24 expression in Arabidopsis under greenhouse conditions and conferred a significantly late flowering phenotype by upregulating OsMADS56 in rice under field conditions. PvPin1 showed subcellular localization in both the nucleus and cytolemma. The 1500-bp sequence of the PvPin1 promoter was cloned, and cis -acting element prediction showed that ABRE and TGACG-motif elements, which responded to abscisic acid (ABA) and methyl jasmonate (MeJA), respectively, were characteristic of P. violascens in comparison with Arabidopsis . On promoter activity analysis, exogenous ABA and MeJA could significantly inhibit PvPin1 expression. These findings suggested that PvPin1 may be a repressor in flowering, and its delay of flowering time could be regulated by ABA and MeJA in bamboo.
Large Scale Density Estimation of Blue and Fin Whales (LSD)
2015-09-30
1 DISTRIBUTION STATEMENT A. Approved for public release; distribution is unlimited. Large Scale Density Estimation of Blue and Fin Whales ...sensors, or both. The goal of this research is to develop and implement a new method for estimating blue and fin whale density that is effective over...develop and implement a density estimation methodology for quantifying blue and fin whale abundance from passive acoustic data recorded on sparse
Evaluation of fins used in underwater swimming.
Pendergast, D R; Mollendorf, J; Logue, C; Samimy, S
2003-01-01
Underwater swimmers use fins which augment thrust to overcome drag and propel the diver. The VdotO2 of swimming as a function of speed, velocity as a function of kick frequency, maximal speed (v), maximal oxygen consumption (VdotO2) and the maximal thrust were determined for eight fins in 10 male divers swimming at 1.25 m depth in a 60 m annular pool. A theoretical analysis of fin cycles was also performed. VdotO2 increased as a second order polynomial as a function of velocity; VdotO2 = 0.045 + 1.65B V + 1.66 (2) V2 (r2 = 0.997), VdotO2 = 0.25 + 1.03 V + 1.83 V2 (r2 = 0.997) and VdotO2 = -0.15 + 2.26 V + 1.49 V2 (r2 = 0.997), for least, average and most economical fins respectively. Kick frequency increased linearly with velocity and had a unique movement path (signature), giving theoretical values that agreed with the measured thrust, drag and efficiency. In conclusion, virtually all thrust comes from the downward power stroke, with rigid fins kicked deep (high drag), while flexible fins are kicked less deep but with higher frequency (low efficiency). Kick depth and frequency explain the performance of the eight tested fins, and should be optimized to enhance diver performance.
NASA Astrophysics Data System (ADS)
Matsukawa, Takashi; Liu, Yongxun; Mori, Takahiro; Morita, Yukinori; Otsuka, Shintaro; O'uchi, Shin-ichi; Fuketa, Hiroshi; Migita, Shinji; Masahara, Meishoku
2017-06-01
The influence of extension doping on parasitic resistance and its variability has been investigated for FinFETs. Electrical characterization of FinFETs and crystallinity evaluation of the doped fin structure are carried out for different fin thicknesses and different donor species for ion implantation, i.e., As and P. Reducing the fin thickness and the use of donor species with a larger mass cause serious degradation in the variability and median value of the parasitic resistance. Crystallinity evaluation by transmission electron microscope reveals that significant crystal defects remain after dopant activation annealing for the cases of smaller fin thickness and the implanted dopant with a larger mass. The unrecovered defects cause serious degradation in the parasitic resistance and its variability. In 1998, he joined the Electrotechnical Laboratory, which is former organization of National Institute of Advanced Industrial Science and Technology (AIST). He has been working on development of front-end process technology, variability issues of the FinFETs and technologies for suppressing the variability. He is now a group leader of the AIST and leads the research on the silicon-based CMOS devices. He is a member of the IEEE Electron Devices Society, and the Japan Society of Applied Physics.
NASA Technical Reports Server (NTRS)
Keynton, Robert J.
1961-01-01
Tests were conducted at Mach numbers of 3.96 and 4.65 in the Langley Unitary Plan wind tunnel to determine the static longitudinal stability characteristics of a fin-stabilized rocket-vehicle configuration which had a rearward facing step located upstream of the fins. Two fin sizes and planforms, a delta and a clipped delta, were tested. The angle of attack was varied from 6 deg to -6 deg and the Reynolds number based on model 6 length was about 10 x 10. The configuration with the larger fins (clipped delta) had a center of pressure slightly rearward of and an initial normal-force-curve slope slightly higher than that of the configuration with the smaller fins (delta) as would be expected. Calculations of the stability parameters gave a slightly lower initial slope of the normal-force curve than measured data, probably because of boundary-layer separation ahead of the step. The calculated center of pressure agreed well with the measured data. Measured and calculated increments in the initial slope of the normal-force curve and in the center of pressure, due to changing fins, were in excellent agreement indicating that separated flow downstream of the step did not influence flow over the fins. This result was consistent with data from schlieren photographs.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Verma, Amit, E-mail: averma@cornell.edu; Nomoto, Kazuki; School of Electrical and Computer Engineering, Cornell University, Ithaca, New York 14853
2016-05-02
Solid-state modulation of 2-dimensional electron gases (2DEGs) with extreme (∼3.3 × 10{sup 14 }cm{sup −2}) densities corresponding to 1/2 electron per interface unit cell at complex oxide heterointerfaces (such as SrTiO{sub 3}/GdTiO{sub 3} or SrTiO{sub 3}/SmTiO{sub 3}) is challenging because it requires enormous gate capacitances. One way to achieve large gate capacitances is by geometrical capacitance enhancement in fin structures. In this work, we fabricate both Au-gated planar field effect transistors (FETs) and Fin-FETs with varying fin-widths on 60 nm SrTiO{sub 3}/5 nm SmTiO{sub 3} thin films grown by hybrid molecular beam epitaxy. We find that the FinFETs exhibit higher gate capacitance comparedmore » to planar FETs. By scaling down the SrTiO{sub 3}/SmTiO{sub 3} fin widths, we demonstrate further gate capacitance enhancement, almost twice compared to the planar FETs. In the FinFETs with narrowest fin-widths, we demonstrate a record 2DEG electron concentration modulation of ∼2.4 × 10{sup 14 }cm{sup −2}.« less
Neural network detected in a presumed vestigial trait: ultrastructure of the salmonid adipose fin
Buckland-Nicks, J. A.; Gillis, M.; Reimchen, T. E.
2012-01-01
A wide variety of rudimentary and apparently non-functional traits have persisted over extended evolutionary time. Recent evidence has shown that some of these traits may be maintained as a result of developmental constraints or neutral energetic cost, but for others their true function was not recognized. The adipose fin is small, fleshy, non-rayed and located between the dorsal and caudal fins on eight orders of basal teleosts and has traditionally been regarded as vestigial without clear function. We describe here the ultrastructure of the adipose fin and for the first time, to our knowledge, present evidence of extensive nervous tissue, as well as an unusual subdermal complex of interconnected astrocyte-like cells equipped with primary cilia. The fin contains neither adipose tissue nor fin rays. Many fusiform actinotrichia, comprising dense striated macrofibrils, support the free edge and connect with collagen cables that link the two sides. These results are consistent with a recent hypothesis that the adipose fin may act as a precaudal flow sensor, where its removal can be detrimental to swimming efficiency in turbulent water. Our findings provide insight to the broader themes of function versus constraints in evolutionary biology and may have significance for fisheries science, as the adipose fin is routinely removed from millions of salmonids each year. PMID:21733904
Control characteristics for wrap-around fins on cruise missiles configurations
NASA Technical Reports Server (NTRS)
Sawyer, W. C.; Monta, W. J.; Carter, W. V.; Alexander, W. K.
1981-01-01
This paper presents selected results of a panel loads study conducted as part of the final phase of an extensive investigation of an air-breathing missile concept employing wrap-around aerodynamic surfaces. Typical results for M = 2.36 are presented for the fin load results, plus a brief review of basic results of the previously reported tests. Vapor screen results are also discussed. The present results indicate that the fin load characteristics are nearly identical for planar and curved fins having the same projected planform and would permit the use of planar-surface predictions for supersonic speeds in the preliminary design stages of missiles employing wrap-around curved fins.
Cooled particle accelerator target
Degtiarenko, Pavel V.
2005-06-14
A novel particle beam target comprising: a rotating target disc mounted on a retainer and thermally coupled to a first array of spaced-apart parallel plate fins that extend radially inwardly from the retainer and mesh without physical contact with a second array of spaced-apart parallel plate fins that extend radially outwardly from and are thermally coupled to a cooling mechanism capable of removing heat from said second array of spaced-apart fins and located within the first array of spaced-apart parallel fins. Radiant thermal exchange between the two arrays of parallel plate fins provides removal of heat from the rotating disc. A method of cooling the rotating target is also described.
NASA Astrophysics Data System (ADS)
Morita, Yukinori; Fukuda, Koichi; Liu, Yongxun; Mori, Takahiro; Mizubayashi, Wataru; O'uchi, Shin-ichi; Fuketa, Hiroshi; Otsuka, Shintaro; Migita, Shinji; Masahara, Meishoku; Endo, Kazuhiko; Ota, Hiroyuki; Matsukawa, Takashi
2017-04-01
We have demonstrated the operation of a CMOS inverter consisting of Si tunnel FinFETs. Both p- and n-type tunnel FinFETs are successfully fabricated and operated on the same SOI wafer. The current mismatch between p- and n-type tunnel FETs is compensated by tuning the number of fin channels. Very low short-circuit current and clear voltage input-output characteristics are obtained. The thin epitaxial channel in the tunnel FinFETs effectively increases the drain current and accordingly reduces the drain capacitance, which could help high-performance tunnel FET CMOS inverter operation.
The Effect of Fin Pitch on Fluid Elastic Instability of Tube Arrays Subjected to Cross Flow of Water
NASA Astrophysics Data System (ADS)
Desai, Sandeep Rangrao; Pavitran, Sampat
2018-02-01
Failure of tubes in shell and tube exchangers is attributed to flow induced vibrations of such tubes. There are different excitations mechanisms due to which flow induced vibration occurs and among such mechanisms, fluid elastic instability is the most prominent one as it causes the most violent vibrations and may lead to rapid tube failures within short time. Fluid elastic instability is the fluid-structure interaction phenomenon which occurs when energy input by the fluid force exceeds energy expended in damping. This point is referred as instability threshold and corresponding velocity is referred as critical velocity. Once flow velocity exceeds critical flow velocity, the vibration amplitude increases very rapidly with flow velocity. An experimental program is carried out to determine the critical velocity at instability for plain and finned tube arrays subjected to cross flow of water. The tube array geometry is parallel triangular with cantilever end condition and pitch ratios considered are 2.6 and 2.1. The objective of research is to determine the effect of increase in pitch ratio on instability threshold for plain tube arrays and to assess the effect of addition of fins as well as increase in fin density on instability threshold for finned tube arrays. Plain tube array with two different pitch ratios; 2.1 and 2.6 and finned tube arrays with same pitch ratio; 2.6 but with two different fin pitches; such as fine (10 fpi) and coarse (4 fpi) are considered for the experimentation. Connors' equation that relates critical velocity at instability to different parameters, on which instability depends, has been used as the basis for analysis and the concept of effective diameter is used for the present investigation. The modal parameters are first suitably modified using natural frequency reduction setup that is already designed and developed to reduce natural frequency and hence to achieve experimental simulation of fluid elastic instability within the limited flow capacity of the pump. The tests are carried out first on plain tube arrays to establish the same as the datum case and results are compared to known results of plain tube arrays and hence the quality of the test rig is also assessed. The fluid elastic vibration tests are then carried out on finned tube arrays with coarse and fine fin pitches and effects of fins and fin pitch on instability threshold are shown. The vibration response of the tube is recorded for each gradually increasing flow rates of water till instability point is reached. The parameters at the instability are then presented in terms of dimensionless parameters to compare them with published results. It is concluded that, arrays with higher pitch ratios are unstable at comparatively higher flow velocities and instability threshold for finned tube arrays is delayed due to addition of the fins. Further, it is concluded that, instability threshold for finned tube arrays with fine fin pitch is delayed compared to coarse fin pitch and hence for increased fin density, instability threshold is delayed. The experimental results in terms of critical velocities obtained for different tube arrays subjected to water cross flow will serve as the base flow rates for air-water cross flow experiments to be conducted in the next phase.
Santy, J E; Kamal, J; Abdul-Rashid, A H; Ibrahim, S
2015-07-01
Percutaneous pinning after closed reduction is commonly used to treat supracondylar fractures of the humerus in children. Minor pin tract infections frequently occur. The aim of this study was to prevent pin tract infections using a rubber stopper to reduce irritation of the skin against the Kirschner (K) wire following percutaneous pinning. Between July 2011 and June 2012, seventeen children with closed supracondylar fracture of the humerus of Gartland types 2 and 3 were treated with this technique. All patients were treated with closed reduction and percutaneous pinning and followed up prospectively. Only one patient, who was a hyperactive child, developed pin tract infection due to softening of the plaster slab. We found using the rubber stopper to be a simple and inexpensive method to reduce pin tract infections following percutaneous pinning.
Santy, JE; Abdul-Rashid, AH; Ibrahim, S
2015-01-01
Percutaneous pinning after closed reduction is commonly used to treat supracondylar fractures of the humerus in children. Minor pin tract infections frequently occur. The aim of this study was to prevent pin tract infections using a rubber stopper to reduce irritation of the skin against the Kirschner (K) wire following percutaneous pinning. Between July 2011 and June 2012, seventeen children with closed supracondylar fracture of the humerus of Gartland types 2 and 3 were treated with this technique. All patients were treated with closed reduction and percutaneous pinning and followed up prospectively. Only one patient, who was a hyperactive child, developed pin tract infection due to softening of the plaster slab. We found using the rubber stopper to be a simple and inexpensive method to reduce pin tract infections following percutaneous pinning. PMID:28435603
Nisar, Nazia; Cuttriss, Abby J; Pogson, Barry J; Cazzonelli, Christopher I
2014-01-01
Cellular auxin homeostasis controls many aspects of plant growth, organogenesis and development. The existence of intracellular auxin transport mediated by endoplasmic reticulum (ER)-localized PIN5, PIN6 and PIN8 proteins is a relatively recent discovery shaping a new era in understanding auxin-mediated growth processes. Here we summarize the importance of PIN6 in mediating intracellular auxin transport during root formation, leaf vein patterning and nectary production. While, it was previously shown that PIN6 was strongly expressed in rosette leaf cell types important in vein formation, here we demonstrate by use a PIN6 promoter-reporter fusion, that PIN6 is also preferentially expressed in the vasculature of the primary root, cotyledons, cauline leaves, floral stem, sepals and the main transmitting tract of the reproductive silique. The strong, vein- specific reporter gene expression patterns enabled by the PIN6 promoter emphasizes that transcriptional control is likely to be a major regulator of PIN6 protein levels, during vasculature formation, and supports the need for ER-localized PIN proteins in selecting specialized cells for vascular function in land plants.
Biological significance of PinX1 telomerase inhibitor in esophageal carcinoma treatment
Fan, Xiang-Kui; Yan, Rui-Hua; Geng, Xiang-Qun; Li, Jing-Shan; Chen, Xiang-Ming; Li, Jian-Zhe
2016-01-01
In the present study, to investigate the expression of PinX1 gene and its functional effects in human esophageal carcinoma (Eca)-109 cell line, expression vectors of human PinX1 (pEGFP-C3-PinX1) and its small interfering RNA (PinX1-FAM-siRNA) were constructed and transfected into Eca-109 cells using Lipofectamine 2000. Firstly, the mRNA expression level of PinX1 was examined using reverse transcription-polymerase chain reaction (RT-PCR). Once successful transfection was achieved, the effects on the mRNA level of human telomerase reverse transcriptase (hTERT), telomerase activity, cell proliferation and apoptosis were examined by semi-quantitative RT-PCR, stretch PCR, MTT assay and flow cytometry, respectively. Analysis of restriction and sequencing demonstrated that the recombining plasmids were successfully constructed. The results also indicated that transfection with pEGFP-C3-PinX1 and PinX1-FAM-siRNA into Eca-109 cells significantly increased PinX1 mRNA, decreased hTERT mRNA by 29.9% (P<0.05), and significantly reduced telomerase activity (P<0.05), inhibited cell growth, and increased the cell apoptotic index from 19.27±0.76 to 49.73±2%. The transfected PinX1-FAM-SiRNA exhibited PinX1 mRNA expression levels that were significantly decreased by 70% (P<0.05), whereas the remaining characteristics of Eca-109 cells, including cell growth, mRNA level of hTERT, telomerase activity and cell apoptotic index were not altered. Exogenous PinX1 has been demonstrated to be highly expressed in human Eca. PinX1 can inhibit human telomerase activity and the expression of hTERT mRNA, reduce tumor cell growth and induce apoptosis. Notably, these inhibitory functions were inhibited by silencing PinX1 in Eca with PinX1-FAM-siRNA. PinX1 was successfully increased and decreased in the present study, demonstrating that it may be a potential telomerase activity inhibitor. As PinX1 is an endogenous telomerase inhibitor, it may be used as a novel tumor-targeted gene therapy. PMID:27698711
Low cost impulse compatible wideband antenna
Rosenbury, Erwin T.; Burke, Gerald J.; Nelson, Scott D.; Stever, Robert D.; Governo, George K.; Mullenhoff, Donald J.
2002-01-01
An antenna apparatus and method for building the antenna is disclosed. Impulse signals travel through a feed point of the antenna with respect to a ground plane. A geometric fin structure is connected to the feed point, and through a termination resistance to the ground plane. A geometric ridge structure connected to the ground is positioned with respect to the fin in order to receive and radiate electromagnetic energy from the impulse signal at a predetermined impedance and over a predetermined set of frequencies. The fin and ridge can be either a wire or a planar surface. The fin and ridge may be disposed within a radiation cavity such as a horn. The radiation cavity is constructed of stamped and etched metal sheets bent and then soldered together. The fin and ridge are also formed from metal sheets or wires. The fin is attached to the feed point and then to the cavity through a termination resistance. The ridge is attached to the cavity and disposed with respect to the fin in order to achieve a particular set of antenna characteristics.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Thomas, L.; Chen, H.; Besant, R.W.
1999-07-01
A special test facility was developed to characterize frost growing on heat exchanger fins where the cold surfaces and the air supply conditions were similar to those experienced in freezers, i.e., cold surface temperatures ranging from {minus}35 C to {minus}40 C, air supply temperatures from {minus}10 C to {minus}20 C, and 80% to 100% relative humidity (RH). This test facility included a test section with removable fins to measure the frost height and mass concentration. Frost height on heat exchanger fins was measured using a new automated laser scanning system to measure the height of frost and its distribution onmore » selected fins. The increase in air pressure loss resulting from frost growth on the fins was measured directly in the test loop. The frost mass accumulation distribution was measured for each test using special pre-etched fins that could be easily subdivided and weighed. The total heat rate was measured using a heat flux meter. These frost-measuring instruments were calibrated and the uncertainty of each is stated.« less
Ionic polymer-metal composite enabled robotic manta ray
NASA Astrophysics Data System (ADS)
Chen, Zheng; Um, Tae I.; Bart-Smith, Hilary
2011-04-01
The manta ray, Manta birostris, demonstrates excellent swimming capabilities; generating highly efficient thrust via flapping of dorsally flattened pectoral fins. In this paper, we present an underwater robot that mimics the swimming behavior of the manta ray. An assembly-based fabrication method is developed to create the artificial pectoral fins, which are capable of generating oscillatory with a large twisting angle between leading and trailing edges. Ionic polymer-metal composite (IPMC) actuators are used as artificial muscles in the fin. Each fin consists of four IPMC beams bonded with a compliant poly(dimethylsiloxane) (PDMS) membrane. By controlling each individual IPMC strips, we are able to generate complex flapping motions. The fin is characterized in terms of tip deflection, tip blocking force, twist angle, and power consumption. Based on the characteristics of the artificial pectoral fin, a small size and free-swimming robotic manta ray is developed. The robot consists of two artificial pectoral fins, a rigid body, and an on-board control unit with a lithium ion rechargeable battery. Experimental results show that the robot swam at a speed of up to 0.055 body length per second (BL/sec).
Fish robotics and hydrodynamics
NASA Astrophysics Data System (ADS)
Lauder, George
2010-11-01
Studying the fluid dynamics of locomotion in freely-swimming fishes is challenging due to difficulties in controlling fish behavior. To provide better control over fish-like propulsive systems we have constructed a variety of fish-like robotic test platforms that range from highly biomimetic models of fins, to simple physical models of body movements during aquatic locomotion. First, we have constructed a series of biorobotic models of fish pectoral fins with 5 fin rays that allow detailed study of fin motion, forces, and fluid dynamics associated with fin-based locomotion. We find that by tuning fin ray stiffness and the imposed motion program we can produce thrust both on the fin outstroke and instroke. Second, we are using a robotic flapping foil system to study the self-propulsion of flexible plastic foils of varying stiffness, length, and trailing edge shape as a means of investigating the fluid dynamic effect of simple changes in the properties of undulating bodies moving through water. We find unexpected non-linear stiffness-dependent effects of changing foil length on self-propelled speed, and as well as significant effects of trailing edge shape on foil swimming speed.
NASA Technical Reports Server (NTRS)
Ratcliffe, James G.; Krueger, Ronald
2006-01-01
One particular concern of polymer matrix composite laminates is the relatively low resistance to delamination cracking, in particular when the dominant type of failure is mode I opening. One method proposed for alleviating this problem involves the insertion pultruded carbon pins through the laminate thickness. The pins, known as z-pins, are inserted into the prepreg laminate using an ultrasonic hammer prior to the curing process, resulting in a field of pins embedded normal to the laminate plane as illustrated in Figure. 1. Pin diameters range between 0.28-mm to 0.5-mm and standard areal densities range from 0.5% to 4%. The z-pins are provided by the manufacturer, Aztex(Registered TradeMark) , in a low-density foam preform, which acts to stabilize orientation of the pins during the insertion process [1-3]. Typical pin materials include boron and carbon fibers embedded in a polymer matrix. A number of methods have been developed for predicting delamination growth in laminates reinforced with z-pins. During a study on the effect of z-pin reinforcement on mode I delamination resistance, finite element analyses of z-pin reinforced double cantilever beam (DCB) specimens were performed by Cartie and Partridge [4]. The z-pin bridging stresses were modeled by applying equivalent forces at the pin locations. Single z-pin pull-out tests were performed to characterize the traction law of the pins under mode I loading conditions. Analytical solutions for delamination growth in z-pin reinforced DCB specimens were independently derived by Robinson and Das [5] and Ratcliffe and O'Brien [6]. In the former case, pin bridging stresses were modeled using a distributed load and in the latter example the bridging stresses were discretely modeled by way of grounded springs. Additionally, Robinson and Das developed a data reduction strategy for calculating mode I fracture toughness, G(sub Ic), from a z-pin reinforced DCB specimen test [5]. In both cases a traction law similar to that adopted by Cartie and Partridge was used to represent z-pin failure under mode I loading conditions. In the current work spring elements available in most commercial finite element codes were used to model z-pins. The traction law used in previous analyses [4-6] was employed to represent z-pin damage. This method is intended for and is limited to simulating z-pins in composite laminate structure containing mode I-dominated delamination cracking. The current technique differs from previous analyses in that spring finite elements (available in commercial codes) are employed for simulating zpins, reducing the complexity of the analysis construction process. Furthermore, the analysis method can be applied to general structure that experiences mode I-dominated delamination cracking, in contrast to existing analytical solutions that are only applicable to coupon DCB specimens.
NASA Astrophysics Data System (ADS)
Hoshino, T.; Hitotsubashi, R.; Miyamoto, K.; Tanimoto, E.; Ueda, J.
STS-95 space experiment has showed that auxin polar transport in etiolated epicotyls of pea (Pisum sativum L. cv. Alaska) seedlings is controlled by gravistimulation. In Arabidopsis thaliana auxin polar transport has considered to be regulated by efflux and influx carrier proteins in plasma membranes, AtPIN1 and AtAUX1, respectively. In order to know how gravistimuli control auxin polar transport in etiolated pea epicotyls at molecular levels, strenuous efforts have been made, resulting in successful isolation of full-length cDNAs of a putative auxin efflux and influx carriers, PsPIN2 and PsAUX1, respectively. Significantly high levels in homology were found on nucleotide and deduced amino acid sequences among PsPIN2, PsPIN1 (accession no. AY222857, Chawla and DeMason, 2003) and AtPINs, and also among PsAUX1, AtAUX1 and their related genes. Phylogenetic analyses based on the deduced amino acid sequences revealed that PsPIN2 belonged to a subclade including AtPIN3, AtPIN4 relating to lateral transport of auxin, while PsPIN1 belonged to the same clade as AtPIN1 relating to auxin polar transport. In the present study, we examined the effects of gravistimuli on the expression of PsPINs and PsAUX1 in etiolated pea seedlings by northern blot analysis. Expression of PsPIN1, PsPIN2 and PsAUX1 in hook region of 3.5-d-old etiolated pea seedlings grown under simulated microgravity conditions on a 3-D clinostat increased as compared with that of the seedlings grown under 1 g conditions. On the other hand, that of PsPIN1 and PsAUX1 in the 1st internode region under simulated microgravity conditions on a 3-D clinostat also increased, while that of PsPIN2 was affected little. These results suggest that expression of PsPIN1, PsPIN2 and PsAUX1 regulating polar/lateral transport of auxin is substantially under the control of gravity. A possible role of PsPINs and PsAUX1 of auxin polar transport in etiolated pea seedlings will also be discussed.
The prolyl isomerase Pin1 modulates development of CD8+ cDC in mice.
Barberi, Theresa J; Dunkle, Alexis; He, You-Wen; Racioppi, Luigi; Means, Anthony R
2012-01-01
Pin1 has previously been described to regulate cells that participate in both innate and adaptive immunity. Thus far, however, no role for Pin1 has been described in modulating conventional dendritic cells, innate antigen presenting cells that potently activate naïve T cells, thereby bridging innate and adaptive immune responses. When challenged with LPS, Pin1-null mice failed to accumulate spleen conventional dendritic cells (cDC). Analysis of steady-state spleen DC populations revealed that Pin1-null mice had fewer CD8+ cDC. This defect was recapitulated by culturing Pin1-null bone marrow with the DC-instructive cytokine Flt3 Ligand. Additionally, injection of Flt3 Ligand for 9 days failed to induce robust expansion of CD8+ cDC in Pin1-null mice. Upon infection with Listeria monocytogenes, Pin1-null mice were defective in stimulating proliferation of adoptively transferred WT CD8+ T cells, suggesting that decreases in Pin1 null CD8+ cDC may affect T cell responses to infection in vivo. Finally, upon analyzing expression of proteins involved in DC development, elevated expression of PU.1 was detected in Pin1-null cells, which resulted from an increase in PU.1 protein half-life. We have identified a novel role for Pin1 as a modulator of CD8+ cDC development. Consistent with reduced numbers of CD8+ cDC in Pin1-null mice, we find that the absence of Pin1 impairs CD8+ T cell proliferation in response to infection with Listeria monocytogenes. These data suggest that, via regulation of CD8+ cDC production, Pin1 may serve as an important modulator of adaptive immunity.
Pu, Wenchen; Li, Jiao; Zheng, Yuanyuan; Shen, Xianyan; Fan, Xin; Zhou, Jian-Kang; He, Juan; Deng, Yulan; Liu, Xuesha; Wang, Chun; Yang, Shengyong; Chen, Qiang; Liu, Lunxu; Zhang, Guolin; Wei, Yu-Quan; Peng, Yong
2018-01-30
Hepatocellular carcinoma (HCC) is a leading cause of cancer death worldwide, but there are few effective treatments. Aberrant microRNA (miRNA) biogenesis is correlated with HCC development. We previously demonstrated that peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1) participates in miRNA biogenesis and is a potential HCC treatment target. However, how Pin1 modulates miRNA biogenesis remains obscure. Here, we present in vivo evidence that Pin1 overexpression is directly linked to the development of HCC. Administration with the Pin1 inhibitor (API-1), a specific small molecule targeting Pin1 peptidyl-prolyl isomerase domain and inhibiting Pin1 cis-trans isomerizing activity, suppresses in vitro cell proliferation and migration of HCC cells. But API-1-induced Pin1 inhibition is insensitive to HCC cells with low Pin1 expression and/or low exportin-5 (XPO5) phosphorylation. Mechanistically, Pin1 recognizes and isomerizes the phosphorylated serine-proline motif of phosphorylated XPO5 and passivates phosphorylated XPO5. Pin1 inhibition by API-1 maintains the active conformation of phosphorylated XPO5 and restores XPO5-driven precursor miRNA nuclear-to-cytoplasm export, activating anticancer miRNA biogenesis and leading to both in vitro HCC suppression and HCC suppression in xenograft mice. Experimental evidence suggests that Pin1 inhibition by API-1 up-regulates miRNA biogenesis by retaining active XPO5 conformation and suppresses HCC development, revealing the mechanism of Pin1-mediated miRNA biogenesis and unequivocally supporting API-1 as a drug candidate for HCC therapy, especially for Pin1-overexpressing, extracellular signal-regulated kinase-activated HCC. (Hepatology 2018). © 2018 by the American Association for the Study of Liver Diseases.
Ebaugh, Larry R.; Sadler, Collin P.; Carter, Gary D.
1992-01-01
An improved fin stabilized projectile including multiple stabilizer fins upon a stabilizer unit situated at the aft end of the projectile is provided, the improvement wherein the stabilizer fins are joined into the stabillizer unit by an injection molded engineering grade polymer.
Potassium Rankine cycle vapor chamber (heat pipe) radiator study
NASA Technical Reports Server (NTRS)
Gerrels, E. E.; Killen, R. E.
1971-01-01
A structurally integrated vapor chamber fin (heat pipe) radiator is defined and evaluated as a potential candidate for rejecting waste heat from the potassium Rankine cycle powerplant. Several vapor chamber fin geometries, using stainless steel construction, are evaluated and an optimum is selected. A comparison is made with an operationally equivalent conduction fin radiator. Both radiators employ NaK-78 in the primary coolant loop. In addition, the Vapor Chamber Fin (VCF) radiator utilizes sodium in the vapor chambers. Preliminary designs are developed for the conduction fin and VCF concepts. Performance tests on a single vapor chamber were conducted to verify the VCF design. A comparison shows the conduction fin radiator easier to fabricate, but heavier in weight, particularly as meteoroid protection requirements become more stringent. While the analysis was performed assuming the potassium Rankine cycle powerplant, the results are equally applicable to any system radiating heat to space in the 900 to 1400 F temperature range.
Low-Power and High-Speed Technique for logic Gates in 20nm Double-Gate FinFET Technology
NASA Astrophysics Data System (ADS)
Priydarshi, A.; Chattopadhyay, M. K.
2016-10-01
The FinFET is the leading example of multigate MOSFETS to substitute conventional single gate MOSFETs for ultimate scaling [1], The FinFET structure is a combination of a thin channel region and a double gate to suppress the short channel effects (SCEs) and Vthvariation [2], By using FinFET,figure of merits viz, ION, IOFF, output resistance, propagation delay, noise margin and leakage power, can be improved for ultra low power and high performance applications[3]. In this paper, a new high speed low power dynamic circuit design technique has been proposed using 20nm FinFETs. By applying the appropriate clock and sleep signal to the back gates of the FinFETs, the proposed circuit can efficiently control the dynamic power, During the pre-charging period, Vth of PMOS is controlled low so that a fast precharging can occur;
DOE Office of Scientific and Technical Information (OSTI.GOV)
Abate, G.L.; Winchenbach, G.L.
Subsonic and transonic aerodynamic data for missiles with solid and slotted wrap around fin configurations are presented. Free-flight aeroballistic tests to obtain this data were conducted at atmospheric pressure over a Mach number range of 0.8 to 1.6. The aerodynamic coefficients and derivatives presented were extracted from the position-attitude-time histories of the experimentally measured trajectories using non-linear numerical integration data reduction routines. Results of this testing and analysis show the static and dynamic stability variations for solid and slotted wrap around fin configurations. The presence of a side moment dependent on pitch angle, inherent to wrap around fin configurations, ismore » measured for both configurations. Results indicate a reduction in the magnitude of this side-moment for missiles with slotted fins. Also, roll dependence with Mach number effects are not present with the slotted fin configurations. Designers should consider these factors whenever wrap around fins are utilized. 14 refs.« less
NASA Astrophysics Data System (ADS)
Utomo, Ilham Satrio; Tjahjana, Dominicus Danardono Dwi Prija; Hadi, Syamsul
2018-02-01
The use of renewable energy in Indonesia is still low. Especially the use of wind energy. Wind turbine Savonius is one turbine that can work with low wind speed. However, Savonius wind turbines still have low efficiency. Therefore it is necessary to modify. Modifications by using the fin are expected to increase the positive drag force by creating a flow that can enter the overlap ratio of the gap. This research was conducted using experimental approach scheme. Parameters generated from the experiment include: power generator, power coefficient, torque coefficient. The experimental data will be collected by variation of fin area, horizontal finning, at wind speed 3 m/s - 4,85 m/s. Experimental results show that with the addition of fin can improve the performance of wind turbine Savonius 11%, and by using the diameter of 115 mm fin is able to provide maximum performance in wind turbine Savonius.
Determination of optimum fin profile for a zero-G capillary drained condenser
NASA Technical Reports Server (NTRS)
Mccormick, John A.; Valenzuela, Javier A.; Choudhury, Dipanker
1990-01-01
This paper presents the analytical formulation and numerical results for heat transfer in a high heat flux condenser that relies on capillary flow along shaped fins (Gregorig surfaces) and a drainage network embedded in the condenser walls. Results are shown for a variety of fin profile shapes in order to show the geometric trade-offs involved in seeking a maximum effective heat transfer coefficient for the fin. Predictions of the model show excellent agreement with previously reported measurements for steam. Based on this work, a profile has been selected for a 2 kW ammonia condenser currently under development for use in space. In that design the fin half width is 0.5 mm and the model predicts a heat transfer coefficient referred to the base of the fin of 9 W/sq cm deg C for a heat flux of 10/W sq cm at the base.
Microgravity condensing heat exchanger
NASA Technical Reports Server (NTRS)
Thomas, Christopher M. (Inventor); Ma, Yonghui (Inventor); North, Andrew (Inventor); Weislogel, Mark M. (Inventor)
2011-01-01
A heat exchanger having a plurality of heat exchanging aluminum fins with hydrophilic condensing surfaces which are stacked and clamped between two cold plates. The cold plates are aligned radially along a plane extending through the axis of a cylindrical duct and hold the stacked and clamped portions of the heat exchanging fins along the axis of the cylindrical duct. The fins extend outwardly from the clamped portions along approximately radial planes. The spacing between fins is symmetric about the cold plates, and are somewhat more closely spaced as the angle they make with the cold plates approaches 90.degree.. Passageways extend through the fins between vertex spaces which provide capillary storage and communicate with passageways formed in the stacked and clamped portions of the fins, which communicate with water drains connected to a pump externally to the duct. Water with no entrained air is drawn from the capillary spaces.
NASA Astrophysics Data System (ADS)
Awasarmol, Umesh Vandeorao; Pise, Ashok T.
2018-02-01
The main objective of this experimental work is to investigate and compare heat transfer enhancement of alternate dwarf fin array at different angles of inclination. In this study, the steady state heat transfer from the full length fin arrays and alternate dwarf fin arrays are measured in natural convection and radiation environment. Largest increase in the Nusselt number was achieved with alternate dwarf fin at angle of orientation 90°, which shows about 28% enhanced heat transfer coefficient as opposed to the full-length fin array with 25% saving in material. In case of non-black FAB, contribution of radiation heat transfer is found to be very small nearly within 1% of the heater input. After coating lamp black contribution of radiation heat transfer is found to increase to about 3-4% of the heater input in the range of temperatures considered in this study.
Hastings, Philip A; Conway, Kevin W
2017-01-17
Gobiesox lanceolatus is described from a single specimen collected from 300 meters depth in the Los Frailes submarine canyon in the southwestern Gulf of California. The "Canyon Clingfish" is unique within Gobiesox in having a lanceolate caudal fin, with the central rays longer than those above and below them. It is also distinguished by 14 dorsal-fin rays (first tiny and unsegmented), 11 anal-fin rays, 28 pectoral-fin rays, anus slightly closer to anal-fin origin than to posterior margin of pelvic disc, and dorsal-fin origin in front of vertical from anus. It is most similar to Gobiesox eugrammus, known from Isla Guadelupe, the coast of outer Baja California and southern California. This is the deepest record for a species of Gobiesox and only four other species of clingfishes are known from greater depths.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Blankenship, H.Lee; Thompson, Dan; United States. Bonneville Power Administration. Division of Fish and Wildlife
The first year of work with development of lasers as a mass marking technique provided both disappointing and encouraging results. A Coumarin Dye 480 laser was used to mark coho salmon in a variety of body locations and with varying energy levels. A ``bleached`` white mark was made void of any pigment. Areas marked included the nape area behind the head and in front of the dorsal fin, slightly above the anal fin, the upper lobe of the caudal fin, the dorsal fin and on the operculum. The mark appeared immediately after being lasered but started to gradually fade aftermore » one month and was fairly completely re-pigmented after three months. Complete removal and notching of the adipose fin was also attempted with a Carbon Dioxide laser. This surgical method of fin removal appears to have advantages over scissor excision (no bleeding or regeneration), and has possible application as part of a device or system which could be employed for mass marking.« less
NASA Astrophysics Data System (ADS)
Uwaba, Tomoyuki; Ito, Masahiro; Nemoto, Junichi; Ichikawa, Shoichi; Katsuyama, Kozo
2014-09-01
The BAMBOO computer code was verified by results for the out-of-pile bundle compression test with large diameter pin bundle deformation under the bundle-duct interaction (BDI) condition. The pin diameters of the examined test bundles were 8.5 mm and 10.4 mm, which are targeted as preliminary fuel pin diameters for the upgraded core of the prototype fast breeder reactor (FBR) and for demonstration and commercial FBRs studied in the FaCT project. In the bundle compression test, bundle cross-sectional views were obtained from X-ray computer tomography (CT) images and local parameters of bundle deformation such as pin-to-duct and pin-to-pin clearances were measured by CT image analyses. In the verification, calculation results of bundle deformation obtained by the BAMBOO code analyses were compared with the experimental results from the CT image analyses. The comparison showed that the BAMBOO code reasonably predicts deformation of large diameter pin bundles under the BDI condition by assuming that pin bowing and cladding oval distortion are the major deformation mechanisms, the same as in the case of small diameter pin bundles. In addition, the BAMBOO analysis results confirmed that cladding oval distortion effectively suppresses BDI in large diameter pin bundles as well as in small diameter pin bundles.
Li, Na; Yuan, Kai; Yan, Feng; Huo, Yuda; Zhu, Tongge; Liu, Xing; Guo, Zhen; Yao, Xuebiao
2009-06-19
Mitotic chromosome movements are orchestrated by interactions between spindle microtubules and chromosomes. It is well known that kinetochore is the major site where microtubule-chromosome attachment occurs. However, the functions of other domains of chromosome such as chromosome periphery have remained elusive. Our previous studies show that PinX1 distributes to chromosome periphery and kinetochore during mitosis, and harbors the microtubule binding activity. Here we report that PinX1 interacts with Nucleolin, a chromosome periphery protein, through its C-termini. Deconvolution microscopic analyses show PinX1 mainly co-localizes with Nucleolin at chromosome periphery in prometaphase. Moreover, depletion of Nucleolin abolishes chromosome periphery localizations of PinX1, suggesting a functional interrelationship between PinX1 and Nucleolin. Importantly, repression of PinX1 and Nucleolin abrogates chromosome segregation in real-time mitosis, validating the functional importance of PinX1-Nucleolin interaction. We propose PinX1 is recruited to chromosome periphery by Nucleolin and a complex of PinX1 and Nucleolin is essential for faithful chromosome congression.
Effects of neutron irradiation on pinning force scaling in state-of-the-art Nb3Sn wires
NASA Astrophysics Data System (ADS)
Baumgartner, T.; Eisterer, M.; Weber, H. W.; Flükiger, R.; Scheuerlein, C.; Bottura, L.
2014-01-01
We present an extensive irradiation study involving five state-of-the-art Nb3Sn wires which were subjected to sequential neutron irradiation up to a fast neutron fluence of 1.6 × 1022 m-2 (E > 0.1 MeV). The volume pinning force of short wire samples was assessed in the temperature range from 4.2 to 15 K in applied fields of up to 7 T by means of SQUID magnetometry in the unirradiated state and after each irradiation step. Pinning force scaling computations revealed that the exponents in the pinning force function differ significantly from those expected for pure grain boundary pinning, and that fast neutron irradiation causes a substantial change in the functional dependence of the volume pinning force. A model is presented, which describes the pinning force function of irradiated wires using a two-component ansatz involving a point-pinning contribution stemming from radiation induced pinning centers. The dependence of this point-pinning contribution on fast neutron fluence appears to be a universal function for all examined wire types.
Brockmeier, Erica K; Ogino, Yukiko; Iguchi, Taisen; Barber, David S; Denslow, Nancy D
2013-03-15
The Eastern and Western mosquitofish (Gambusia holbrooki and G. affinis) are potential bioindicator organisms for endocrine disruptors. Male mosquitofish have an elongated anal fin (gonopodium) used for internal fertilization whose formation is driven by androgens. Normal female mosquitofish have a normal, rounded anal fin which undergoes elongation into a gonopodium structure when female mosquitofish are exposed to androgenic chemicals. Significant issues with using mosquitofish as a bioindicator include the lack of knowledge on how anal fin growth in females corresponds to endpoints relevant to biological integrity and the lack of information on the molecular pathways that regulate anal fin growth. The objectives of this study were to understand how androgen-induced anal fin elongation relates to changes in endpoints related to the female reproductive system and to understand how anal fin elongation occurs in androgen-exposed female mosquitofish. To achieve these objectives, adult female G. holbrooki were exposed to a vehicle control or one of three doses of the androgen 17β-trenbolone (TB) at nominal concentrations of 0.1, 1 or 10 μg TB/L. Anal fin measurements were taken and livers were used for quantitative polymerase chain reaction analysis of vitellogenin (vtg) mRNA expression at multiple time points. 10 μg TB/L induced anal fin elongation after 7 days of treatment (one-way ANOVA, p<0.05) as did 0.1 and 1 μg TB/L at later time points (one-way ANOVA, p<0.05). 10 μg TB/L significantly reduced hepatic vtg gene expression at all time points assessed (one-way ANOVA, p<0.05). There was no correlation between anal fin elongation levels and vtg gene expression (Spearman's ρ, p>0.05). In a separate experiment, female G. holbrooki and G. affinis were exposed to the vehicle control or 1 μg TB/L. Anal fins were used for qualitative gene expression analysis of the genes sonic hedgehog (shh), muscle segment homeobox C (msxC), and fibroblast growth factor receptor 1 (fgfr1) by in situ hybridization. Shh was expressed in the distal tip of the gonopodium while msxC and fgfr1 were more widely expressed along the same anal fin rays during androgen exposure. These data provide insight into the molecular pathways involved in anal fin elongation and pave the way for future work toward developing the mosquitofish into a bioindicator organism for endocrine disruptors. Copyright © 2012 Elsevier B.V. All rights reserved.
NASA Astrophysics Data System (ADS)
Liu, Hanlin; Troolin, Daniel; Hortensius, Ruben; Pothos, Stamatios; Curet, Oscar
2017-11-01
An undulating fin represents a remarkable propulsion model for underwater vehicles due to its high propulsive efficiency and considerable locomotor capabilities. In this work, we used a bio-inspired vessel, the KnifeBot to demonstrate the maneuverability of undulating fin propulsion, including forward-backward swimming, station keeping and vertical swimming. This self-contained robotic system uses an undulating ventral fin as the propulsor and features a slender 3D-printed hull with 16 motors, 2 batteries and electronic boards encapsulated inside. We tested the robot in a water-filled tank and used volumetric particle image velocimetry (V3V PIV) to investigate the three-dimensional flow features and vortex structures generated by the undulating ribbon fin in free-swimming maneuvers. Our results indicate that in the forward swimming, a series of vortex tubes are shed off the fin edge. A streamwise jet at an oblique angle to the fin is generated in association with the vortex tubes propelling the robot forward as well as pitching it up. For the hovering maneuver with inward counter-propagating waves. The streamlines develop vertically downward with the tip vortex shed from the fin edge. This downward jet provides substantial heave force for the robot to swim upward or perform station keeping. Our findings will be useful for understanding the mechanical basis of undulating fin propulsion and facilitate the development of bio-inspired vehicles using undulatory propellers. Office of Naval Research under Award Number N00014-16-1-2505.
Areia, Neide P; Major, Sofia; Relvas, Ana P
2017-10-01
The aim of this study was to validate the Portuguese version of the Family Inventory of Needs (FIN). The FIN aims to measure important family needs and their fulfilment by a healthcare team. This cross-sectional study involved a sample of 364 family members of cancer patients, recruited from three medical institutions and through online recruitment. Three instruments were used: a socio-demographic questionnaire, the FIN and the Brief Symptom Inventory - 18 (BSI-18). Construct validity and reliability were considered regarding the FIN's psychometric properties. The method used to determine construct validity was factor structure analysis (confirmatory factor analysis), inter-factor correlations (Spearman's rank correlation) and convergent validity (Spearman's rank correlation). To assess scale reliability, the FIN's internal consistency was evaluated (Cronbach's alpha coefficient). Descriptive and frequency statistics and tests to compare means were used to assess important needs and to what extent they were met. The four-factor structure of the FIN was confirmed. Thus, the FIN has four domains: Basic Information, Information on treatment and care, Support and Patient Comfort. Convergent validity with the BSI-18 was verified. Both subscales of the FIN and each domain exceeded the minimum reliability standard of 0.70. Family members also reported important needs that were not adequately met by healthcare professionals. The Portuguese version of the FIN seems to be a reliable and valid tool for identifying cancer patients' important family needs and to what extent these are met. Copyright © 2017 Elsevier Ltd. All rights reserved.
Nakatsu, Yusuke; Sakoda, Hideyuki; Kushiyama, Akifumi; Zhang, Jun; Ono, Hiraku; Fujishiro, Midori; Kikuchi, Takako; Fukushima, Toshiaki; Yoneda, Masayasu; Ohno, Haruya; Horike, Nanao; Kanna, Machi; Tsuchiya, Yoshihiro; Kamata, Hideaki; Nishimura, Fusanori; Isobe, Toshiaki; Ogihara, Takehide; Katagiri, Hideki; Oka, Yoshitomo; Takahashi, Shin-ichiro; Kurihara, Hiroki; Uchida, Takafumi; Asano, Tomoichiro
2011-01-01
Peptidyl-prolyl cis/trans isomerase NIMA-interacting 1 (Pin1) is a unique enzyme that associates with the pSer/Thr-Pro motif and catalyzes cis-trans isomerization. We identified Pin1 in the immunoprecipitates of overexpressed IRS-1 with myc and FLAG tags in mouse livers and confirmed the association between IRS-1 and Pin1 by not only overexpression experiments but also endogenously in the mouse liver. The analysis using deletion- and point-mutated Pin1 and IRS-1 constructs revealed the WW domain located in the N terminus of Pin1 and Ser-434 in the SAIN (Shc and IRS-1 NPXY binding) domain of IRS-1 to be involved in their association. Subsequently, we investigated the role of Pin1 in IRS-1 mediation of insulin signaling. The overexpression of Pin1 in HepG2 cells markedly enhanced insulin-induced IRS-1 phosphorylation and its downstream events: phosphatidylinositol 3-kinase binding with IRS-1 and Akt phosphorylation. In contrast, the treatment of HepG2 cells with Pin1 siRNA or the Pin1 inhibitor Juglone suppressed these events. In good agreement with these in vitro data, Pin1 knock-out mice exhibited impaired insulin signaling with glucose intolerance, whereas adenoviral gene transfer of Pin1 into the ob/ob mouse liver mostly normalized insulin signaling and restored glucose tolerance. In addition, it was also demonstrated that Pin1 plays a critical role in adipose differentiation, making Pin1 knock-out mice resistant to diet-induced obesity. Importantly, Pin1 expression was shown to be up-regulated in accordance with nutrient conditions such as food intake or a high-fat diet. Taken together, these observations indicate that Pin1 binds to IRS-1 and thereby markedly enhances insulin action, essential for adipogenesis. PMID:21454638
NASA Technical Reports Server (NTRS)
Haskin, Henry H. (Inventor); Vasquez, Peter (Inventor)
2013-01-01
A flame holder system includes a modified torch body and a ceramic flame holder. Catch pin(s) are coupled to and extend radially out from the torch body. The ceramic flame holder has groove(s) formed in its inner wall that correspond in number and positioning to the catch pin(s). Each groove starts at one end of the flame holder and can be shaped to define at least two 90.degree.turns. Each groove is sized to receive one catch pin therein when the flame holder is fitted over the end of the torch body. The flame holder is then manipulated until the catch pin(s) butt up against the end of the groove(s).
Study of Damped Set-Back Pins for S and A Mechanisms.
1976-11-01
arm device for artillery munitions. This damped set-back pin assembly is one of two safety features on a S and A device used in the M739 PD/XM587 ET...The damped set-back pin study program was for the design, testing, fabrication, and delivery and damped set-back pin assemblies for use in a safe and...fuzes for a rotating projectile. A pin, porous disc, return spring, floating O-ring, and sleeve comprise the selected damped set-back pin assembly
Benchmarking of calculation schemes in APOLLO2 and COBAYA3 for WER lattices
DOE Office of Scientific and Technical Information (OSTI.GOV)
Zheleva, N.; Ivanov, P.; Todorova, G.
This paper presents solutions of the NURISP WER lattice benchmark using APOLLO2, TRIPOLI4 and COBAYA3 pin-by-pin. The main objective is to validate MOC based calculation schemes for pin-by-pin cross-section generation with APOLLO2 against TRIPOLI4 reference results. A specific objective is to test the APOLLO2 generated cross-sections and interface discontinuity factors in COBAYA3 pin-by-pin calculations with unstructured mesh. The VVER-1000 core consists of large hexagonal assemblies with 2 mm inter-assembly water gaps which require the use of unstructured meshes in the pin-by-pin core simulators. The considered 2D benchmark problems include 19-pin clusters, fuel assemblies and 7-assembly clusters. APOLLO2 calculation schemes withmore » the step characteristic method (MOC) and the higher-order Linear Surface MOC have been tested. The comparison of APOLLO2 vs. TRIPOLI4 results shows a very close agreement. The 3D lattice solver in COBAYA3 uses transport corrected multi-group diffusion approximation with interface discontinuity factors of Generalized Equivalence Theory (GET) or Black Box Homogenization (BBH) type. The COBAYA3 pin-by-pin results in 2, 4 and 8 energy groups are close to the reference solutions when using side-dependent interface discontinuity factors. (authors)« less
A low power radiofrequency pulse for simultaneous multislice excitation and refocusing.
Eichner, Cornelius; Wald, Lawrence L; Setsompop, Kawin
2014-10-01
Simultaneous multislice (SMS) acquisition enables increased temporal efficiency of MRI. Nonetheless, MultiBand (MB) radiofrequency (RF) pulses used for SMS can cause large energy deposition. Power independent of number of slices (PINS) pulses reduce RF power at cost of reduced bandwidth and increased off-resonance dependency. This work improves PINS design to further reduce energy deposition, off-resonance dependency and peak power. Modifying the shape of MB RF-pulses allows for mixing with PINS excitation, creating a new pulse type with reduced energy deposition and SMS excitation characteristics. Bloch Simulations were used to evaluate excitation and off-resonance behavior of this "MultiPINS" pulse. In this work, MultiPINS was used for whole-brain MB = 3 acquisition of high angular and spatial resolution diffusion MRI at 7 Tesla in 3 min. By using MultiPINS, energy transmission and peak power for SMS imaging can be significantly reduced compared with PINS and MB pulses. For MB = 3 acquisition in this work, MultiPINS reduces energy transmission by up to ∼50% compared with PINS pulses. The energy reduction was traded off to shorten the MultiPINS pulse, yielding higher signal at off-resonances for spin-echo acquisitions. MB and PINS pulses can be combined to enable low energy and peak power SMS acquisition. Copyright © 2014 Wiley Periodicals, Inc.
COT phosphorylates prolyl-isomerase Pin1 to promote tumorigenesis in breast cancer.
Kim, Garam; Khanal, Prem; Kim, Jin Young; Yun, Hyo-Jeong; Lim, Sung-Chul; Shim, Jung-Hyun; Choi, Hong Seok
2015-06-01
Pin1, a conserved eukaryotic Peptidyl-prolyl cis/trans isomerase, has profound effects on numerous key-signaling molecules, and its deregulation contributes to disease, particularly cancer. Although Pin1-mediated prolyl isomerization is an essential and novel regulatory mechanism for protein phosphorylation, little is known about the upstream signaling pathway(s) that regulates Pin1 activity. Here, we identify MAP3K-related serine-threonine kinase (the gene encoding COT/Tpl2) as a kinase responsible for phosphorylation of Pin1 Ser16. COT interacts with and phosphorylates Pin1 on Ser16. Consequently, Pin1 Ser16 phosphorylation by COT increases cyclin D1 abundance and enhances tumorigenecity of MCF7 cells. In contrast, depletion of COT in MCF7 cells leads to downregulation of Pin1 Ser16 phosphorylation, which subsequently decrease cyclin D1 levels, inhibiting tumorigenecity of MCF7 cells. In a xenograft model, treatment of TKI, a COT inhibitor, and Juglone, a Pin1 inhibitor, abrogates tumor growth. In human breast cancer patients, immunohistochemical staining shows that Pin1 pSer16 levels are positively correlated with COT levels, providing strong evidence for an essential role of the COT/Pin1 axis in conveying oncogenic signals to promote aggressiveness in human breast cancer. © 2013 Wiley Periodicals, Inc.
Connection stiffness and dynamical docking process of flux pinned spacecraft modules
NASA Astrophysics Data System (ADS)
Lu, Yong; Zhang, Mingliang; Gao, Dong
2014-02-01
This paper describes a novel kind of potential flux pinned docking system that consists of guidance navigation and control system, the traditional extrusion type propulsion system, and a flux pinned docking interface. Because of characteristics of passive stability of flux pinning, the docking control strategy of flux pinned docking system only needs a series of sequential control rather than necessary active feedback control, as well as avoidance of hazardous collision accident. The flux pinned force between YBaCuO (YBCO) high temperature superconductor bulk and permanent magnet is able to be given vent based on the identical current loop model and improved image dipole model, which can be validated experimentally. Thus, the connection stiffness between two flux pinned spacecraft modules can be calculated based on Hooke's law. This connection stiffness matrix at the equilibrium position has the positive definite performance, which can validate the passively stable connection of two flux pinned spacecraft modules theoretically. Furthermore, the relative orbital dynamical equation of two flux pinned spacecraft modules can be established based on Clohessy-Wiltshire's equations and improved image dipole model. The dynamical docking process between two flux pinned spacecraft modules can be obtained by way of numerical simulation, which suggests the feasibility of flux pinned docking system.
Connection stiffness and dynamical docking process of flux pinned spacecraft modules
DOE Office of Scientific and Technical Information (OSTI.GOV)
Lu, Yong; Zhang, Mingliang, E-mail: niudun12@126.com; Gao, Dong
2014-02-14
This paper describes a novel kind of potential flux pinned docking system that consists of guidance navigation and control system, the traditional extrusion type propulsion system, and a flux pinned docking interface. Because of characteristics of passive stability of flux pinning, the docking control strategy of flux pinned docking system only needs a series of sequential control rather than necessary active feedback control, as well as avoidance of hazardous collision accident. The flux pinned force between YBaCuO (YBCO) high temperature superconductor bulk and permanent magnet is able to be given vent based on the identical current loop model and improvedmore » image dipole model, which can be validated experimentally. Thus, the connection stiffness between two flux pinned spacecraft modules can be calculated based on Hooke's law. This connection stiffness matrix at the equilibrium position has the positive definite performance, which can validate the passively stable connection of two flux pinned spacecraft modules theoretically. Furthermore, the relative orbital dynamical equation of two flux pinned spacecraft modules can be established based on Clohessy-Wiltshire's equations and improved image dipole model. The dynamical docking process between two flux pinned spacecraft modules can be obtained by way of numerical simulation, which suggests the feasibility of flux pinned docking system.« less
Gan, Zengyu; Wang, Yi; Wu, Ting; Xu, Xuefeng; Zhang, Xinzhong; Han, Zhenhai
2018-03-01
Lower promoter activity is closely associated with lower MdPIN1b expression in the M9 interstem, which might contribute to the dwarfing effect in apple trees. Apple trees grafted onto dwarfing rootstock Malling 9 (M9) produce dwarfing tree architecture with high yield and widely applying in production. Previously, we have reported that in Malus 'Red Fuji' (RF) trees growing on M9 interstem and Baleng Crab (BC) rootstock, IAA content was relatively higher in bark tissue of M9 interstem than that in scion or rootstock. As IAA polar transportation largely depends on the PIN-FORMED (PIN) auxin efflux carrier. Herein, we identify two putative auxin efflux carrier genes in Malus genus, MdPIN1a and MdPIN1b, which were closely related to the AtPIN1. We found that MdPIN1b was expressed preferentially in BC and M9, and the expression of MdPIN1b was significantly lower in the phloem of M9 interstem than that in the scion and rootstock. The distinct expression of MdPIN1b and IAA content were concentrated in the cambium and adjacent xylem or phloem, and MdPIN1b protein was localized on cell plasma membrane in onion epidermal cells transiently expressing 35S:MdPIN1b-GFP fusion protein. Interestingly, an MdPIN1b mutant allele in the promoter region upstream of M9 exhibited decreased MdPIN1b expression compared to BC. MdPIN1b over-expressing interstem in tobacco exhibited increased polar auxin transport. It is proposed that natural allelic differences decreased promoter activity is closely associated with lower MdPIN1b expression in the M9 interstem, which might limit the basipetal transport of auxin, and in turn might contribute to the dwarfing effect. Taken together, these results reveal allelic variation underlying an important apple rootstock trait, and specifically a novel molecular genetic mechanism underlying dwarfing mechanism.
F-16 Ventral Fin Buffet Alleviation Using Piezoelectric Actuators
2009-09-01
collocated design to alleviate the vibrations of the first two modes of the ventral fin. A switching amplifier was de - signed and custom built to drive the...6M per year [22]. 1 Figure 1.1: LANTIRN Pod and Ventral Fin Locations [cour- tesy USAF] Buffet induced vibrations affect more than just vertical tail...appropriate sensors and actuators for the ventral fin. Several de - viations were necessary, including individual actuator size and orientation and the
Addressing FinFET metrology challenges in 1X node using tilt-beam CD-SEM
NASA Astrophysics Data System (ADS)
Zhang, Xiaoxiao; Zhou, Hua; Ge, Zhenhua; Vaid, Alok; Konduparthi, Deepasree; Osorio, Carmen; Ventola, Stefano; Meir, Roi; Shoval, Ori; Kris, Roman; Adan, Ofer; Bar-Zvi, Maayan
2014-04-01
At 1X node, 3D FinFETS raise a number of new metrology challenges. Gate height and fin height are two of the most important parameters for process control. At present there is a metrology gap in inline in-die measurement of these parameters. In order to fill this metrology gap, in-column beam tilt has been developed and implemented on Applied Materials V4i+ top-down CD-SEM for height measurement. A low tilt (5°) beam and a high tilt (14°) beam have been calibrated to obtain two sets of images providing measurement of sidewall edge width to calculate height in the host. Evaluations are done with applications in both gate height and fin height. TEM correlation with R2 being 0.89 and precision of 0.81nm have been achieved on various in-die features in gate height application. Fin height measurement shows less accuracy (R2 being 0.77) and precision (1.49 nm) due to challenges brought by fin geometry, yet still promising as first attempt. Sensitivity to DOE offset, die-to-die and in-die variation is demonstrated in both gate height and fin height. Process defect is successfully captured from inline wafers with gate height measurement implemented in production. This is the first successful demonstration of inline in-die gate height measurement for 14nm FinFET process control.
A new basal galeomorph shark (Synechodontiformes, Neoselachii) from the Early Jurassic of Europe
NASA Astrophysics Data System (ADS)
Klug, Stefanie; Kriwet, Jürgen
2008-05-01
Palaeospinacids are a group of basal galeomorph sharks and are placed in the order Synechodontiformes (Chondrichthyes, Neoselachii) ranging from the Permian to the Eocene. Currently, there is a controversy concerning the identity of diagnostic characters for distinguishing palaeospinacid genera because of very similar dental morphologies and the scarcity of articulated skeletal material. The most notable character for distinguishing species within the Palaeospinacidae is, however, the dental morphology. The main dental character uniting all palaeospinacids is the very specialised pseudopolyaulacorhize root vascularisation. A re-examination of articulated neoselachian skeletons from the Lower Jurassic of Lyme Regis (England) and Holzmaden (S Germany), and recently discovered specimens from the Upper Jurassic of the Solnhofen area and Nusplingen (S Germany) has yielded several hitherto unrecognised complete skeletons of the palaeospinacids Synechodus and Paraorthacodus enabling a re-evaluation of characters. These specimens indicate that the number of dorsal fins and the presence or absence of dorsal fin spines represent important features for identifying palaeospinacids. Synechodus bears two dorsal fins without fin spines, whereas Paraorthacodus only has a single dorsal fin lacking a fin spine directly in front of the caudal fin. All palaeospinacids from the Early Jurassic have two spines supporting the dorsal fins and are consequently assigned to a new genus, Palidiplospinax nov. gen. Three species are placed into the new taxon: Synechodus enniskilleni, S. occultidens and S. smithwoodwardi.
NASA Astrophysics Data System (ADS)
Weber, Daniel; Schrod, Jann; Curtius, Joachim; Haunold, Werner; Thomson, Erik; Bingemer, Heinz
2016-04-01
The measurement of atmospheric ice nucleating particles (INP) is still challenging. In the absence of easily applicable INP standards the intercomparison of different methods during collaborative laboratory and field workshops is a valuable tool that can shine light on the performance of individual methods for the measurement of INP [1]. FIN-2 was conducted in March 2015 at the AIDA facility in Karlsruhe as an intercomparison of mobile instruments for measuring INP [2]. FIN-3 was a field campaign at the Desert Research Institutes Storm Peak Laboratory in Colorado in September 2015 [3]. The FRankfurt Ice nucleation Deposition freezinG Experiment (FRIDGE) participated in both experiments. FRIDGE measures ice nucleating particles by electrostatic precipitation of aerosol particles onto Si-wafers in a collection unit, followed by activation, growth, and optical detection of ice crystals on the substrate in an isostatic diffusion chamber [4,5]. We will present and discuss results of our measurements of deposition/condensation INP and of immersion INP with FRIDGE during FIN-2 and FIN-3. Acknowledgements: The valuable contributions of the FIN organizers and their institutions, and of the FIN Workshop Science team are gratefully acknowledged. Our work was supported by Deutsche Forschungsgemeinschaft (DFG) under the Research Unit FOR 1525 (INUIT) and the EU FP7-ENV- 2013 BACCHUS project under Grant Agreement 603445.
Klein, Zachary B.; Bonvechio, Timothy F.; Bowen, Bryant R.; Quist, Michael C.
2017-01-01
Sagittal otoliths are the preferred aging structure for Micropterus spp. (black basses) in North America because of the accurate and precise results produced. Typically, fisheries managers are hesitant to use lethal aging techniques (e.g., otoliths) to age rare species, trophy-size fish, or when sampling in small impoundments where populations are small. Therefore, we sought to evaluate the precision and accuracy of 2 non-lethal aging structures (i.e., anal fin spines, dorsal fin spines) in comparison to that of sagittal otoliths from known-age Micropterus salmoides (Largemouth Bass; n = 87) collected from the Ocmulgee Public Fishing Area, GA. Sagittal otoliths exhibited the highest concordance with true ages of all structures evaluated (coefficient of variation = 1.2; percent agreement = 91.9). Similarly, the low coefficient of variation (0.0) and high between-reader agreement (100%) indicate that age estimates obtained from sagittal otoliths were the most precise. Relatively high agreement between readers for anal fin spines (84%) and dorsal fin spines (81%) suggested the structures were relatively precise. However, age estimates from anal fin spines and dorsal fin spines exhibited low concordance with true ages. Although use of sagittal otoliths is a lethal technique, this method will likely remain the standard for aging Largemouth Bass and other similar black bass species.
Jerve, Anna; Johanson, Zerina; Ahlberg, Per; Boisvert, Catherine
2014-01-01
Fin spines are commonly known from fossil gnathostomes (jawed vertebrates) and are usually associated with paired and unpaired fins. They are less common among extant gnathostomes, being restricted to the median fins of certain chondrichthyans (cartilaginous fish), including chimaerids (elephant sharks) and neoselachians (sharks, skates, and rays). Fin spine growth is of great interest and relevance but few studies have considered their evolution and development. We investigated the development of the fin spine of the chimaerid Callorhinchus milii using stained histological sections from a series of larval, hatchling, and adult individuals. The lamellar trunk dentine of the Callorhinchus spine first condenses within the mesenchyme, rather than at the contact surface between mesenchyme and epithelium, in a manner more comparable to dermal bone formation than to normal odontode development. Trabecular dentine forms a small component of the spine under the keel; it is covered externally with a thin layer of lamellar trunk dentine, which is difficult to distinguish in sectioned adult spines. We suggest that the distinctive characteristics of the trunk dentine may reflect an origin through co-option of developmental processes involved in dermal bone formation. Comparison with extant Squalus and a range of fossil chondrichthyans shows that Callorhinchus is more representative than Squalus of generalized chondrichthyan fin-spine architecture, highlighting its value as a developmental model organism. © 2014 Wiley Periodicals, Inc.
Lu, Jing; Giles, Sam; Friedman, Matt; den Blaauwen, Jan L; Zhu, Min
2016-06-20
Osteichthyans comprise two divisions, each containing over 32,000 living species [1]: Sarcopterygii (lobe-finned fishes and tetrapods) and Actinopterygii (ray-finned fishes). Recent discoveries from China highlight the morphological disparity of early sarcopterygians and extend their origin into the late Silurian [2-4]. By contrast, the oldest unambiguous actinopterygians are roughly 30 million years younger, leaving a long temporal gap populated by fragments and rare body fossils of controversial phylogenetic placement [5-10]. Here we reinvestigate the enigmatic osteichthyan Meemannia from the Early Devonian (∼415 million years ago) of China, previously identified as an exceptionally primitive lobe-finned fish [3, 7, 11, 12]. Meemannia combines "cosmine"-like tissues taken as evidence of sarcopterygian affinity with actinopterygian-like skull roof and braincase geometry, including endoskeletal enclosure of the spiracle and a lateral cranial canal. We report comparable histological structures in undoubted ray-finned fishes and conclude that they are general osteichthyan features. Phylogenetic analysis places Meemannia as an early-diverging ray-finned fish, resolving it as the sister lineage of Cheirolepis [13] plus all younger actinopterygians. This brings the first appearance of ray-fins more in line with that of lobe-fins and fills a conspicuous faunal gap in the otherwise diverse late Silurian-earliest Devonian vertebrate faunas of the South China Block [4]. Copyright © 2016 The Author(s). Published by Elsevier Ltd.. All rights reserved.
A novel trapezoid fin pattern applicable for air-cooled heat sink
NASA Astrophysics Data System (ADS)
Chen, Chien-Hung; Wang, Chi-Chuan
2015-11-01
The present study proposed a novel step or trapezoid surface design applicable to air-cooled heat sink under cross flow condition. A total of five heat sinks were made and tested, and the corresponding fin patterns are (a) plate fin; (b) step fin (step 1/3, 3 steps); (c) 2-step fin (step 1/2, 2 steps); (d) trapezoid fin (trap 1/3, cutting 1/3 length from the rear end) and (e) trapezoid fin (trap 1/2, cutting 1/2 length from the rear end). The design is based on the heat transfer augmentation via (1) longer perimeter of entrance region and (2) larger effective temperature difference at the rear part of the heat sink. From the test results, it is found that either step or trapezoid design can provide a higher heat transfer conductance and a lower pressure drop at a specified frontal velocity. The effective conductance of trap 1/3 design exceeds that of plate surface by approximately 38 % at a frontal velocity of 5 m s-1 while retains a lower pressure drop of 20 % with its surface area being reduced by 20.6 %. For comparisons exploiting the overall thermal resistance versus pumping power, the resultant thermal resistance of the proposed trapezoid design 1/3, still reveals a 10 % lower thermal resistance than the plate fin surface at a specified pumping power.
NASA Astrophysics Data System (ADS)
Liu, Song; Jin, Hua; Song, KeWei; Wang, LiangChen; Wu, Xiang; Wang, LiangBi
2017-10-01
The heat transfer performance of the tube bank fin heat exchanger is limited by the air-side thermal resistance. Thus, enhancing the air-side heat transfer is an effective method to improve the performance of the heat exchanger. A new fin pattern with flow redistributors and curved triangular vortex generators is experimentally studied in this paper. The effects of the flow redistributors located in front of the tube stagnation point and the curved vortex generators located around the tube on the characteristics of heat transfer and pressure drop are discussed in detail. A performance comparison is also carried out between the fins with and without flow redistributors. The experimental results show that the flow redistributors stamped out from the fin in front of the tube stagnation points can decrease the friction factor at the cost of decreasing the heat transfer performance. Whether the combination of the flow redistributors and the curved vortex generators will present a better heat transfer performance depends on the size of the curved vortex generators. As for the studied two sizes of vortex generators, the heat transfer performance is promoted by the flow redistributors for the fin with larger size of vortex generators and the performance is suppressed by the flow redistributors for the fin with smaller vortex generators.
NASA Astrophysics Data System (ADS)
Moehler, O.; Cziczo, D. J.; DeMott, P. J.; Hiranuma, N.; Petters, M. D.
2015-12-01
The role of aerosol particles for ice formation in clouds is one of the largest uncertainties in understanding the Earth's weather and climate systems, which is related to the poor knowledge of ice nucleation microphysics or of the nature and atmospheric abundance of ice nucleating particles (INPs). During the recent years, new mobile instruments were developed for measuring the concentration, size and chemical composition of INPs, which were tested during the three-part Fifth International Ice Nucleation (FIN) workshop. The FIN activities addressed not only instrument issues, but also important science topics like the nature of atmospheric INP and cloud ice residuals, the ice nucleation activity of relevant atmospheric aerosols, or the parameterization of ice formation in atmospheric weather and climate models. The first activity FIN-1 was conducted during November 2014 at the AIDA cloud chamber. It involved co-locating nine single particle mass spectrometers to evaluate how well they resolve the INP and ice residual composition and how spectra from different instruments compare for relevant atmospheric aerosols. We conducted about 90 experiments with mineral, carbonaceous and biological aerosol types, some also coated with organic and inorganic compounds. The second activity FIN-2 was conducted during March 2015 at the AIDA facility. A total of nine mobile INP instruments directly sampled from the AIDA aerosol chambers. Wet suspension and filter samples were also taken for offline INP processing. A refereed blind intercomparison was conducted during two days of the FIN-2 activity. The third activity FIN-3 will take place at the Desert Research Institute's Storm Peak Laboratory (SPL) in order to test the instruments' performance in the field. This contribution will introduce the FIN activities, summarize first results from the formal part of FIN-2, and discuss selected results, mainly from FIN-1 for the effect of coating on the ice nucleation (IN) by mineral aerosols. The coating with both secondary organic compounds and sulphuric acid was conducted in the AIDA chamber at relevant temperatures and precursor concentrations and was monitored with the particle mass spectrometers. Already very thin, atmospherically relevant coatings reduced deposition IN, but had little effect on immersion freezing.
NASA Astrophysics Data System (ADS)
Shan, Hangying; Xiao, Jun; Chu, Qiyi
2018-05-01
The Z-Pin interfacial bond properties play an important role in the structural performance of X-Cor® sandwich structures. This paper presents an experimental investigation on bond-slip behavior of Z-Pin interfaces using Z-Pin pull-out test. Based on the experimental data the whole Z-Pin pull-out process consists of three stages: initial bonding, debonding and frictional sliding. Comparative experimental study on the influence of design parameters on bond-slip behavior of Z-Pin interfaces has also been performed. Numerical analyses were conducted with the ABAQUS finite element (FE) program to simulate the Z-Pins bond-slip response of the pull-out test. The Z-Pins interfacial bond-slip behavior was implemented using nonlinear spring elements characterized with the constitutive relation from experimental results. Numerical results were validated by comparison with experimental data, and reasonably good agreement was achieved between experimental and analytical pull-out force-slip curves.
A covalent PIN1 inhibitor selectively targets cancer cells by a dual mechanism of action
NASA Astrophysics Data System (ADS)
Campaner, Elena; Rustighi, Alessandra; Zannini, Alessandro; Cristiani, Alberto; Piazza, Silvano; Ciani, Yari; Kalid, Ori; Golan, Gali; Baloglu, Erkan; Shacham, Sharon; Valsasina, Barbara; Cucchi, Ulisse; Pippione, Agnese Chiara; Lolli, Marco Lucio; Giabbai, Barbara; Storici, Paola; Carloni, Paolo; Rossetti, Giulia; Benvenuti, Federica; Bello, Ezia; D'Incalci, Maurizio; Cappuzzello, Elisa; Rosato, Antonio; Del Sal, Giannino
2017-06-01
The prolyl isomerase PIN1, a critical modifier of multiple signalling pathways, is overexpressed in the majority of cancers and its activity strongly contributes to tumour initiation and progression. Inactivation of PIN1 function conversely curbs tumour growth and cancer stem cell expansion, restores chemosensitivity and blocks metastatic spread, thus providing the rationale for a therapeutic strategy based on PIN1 inhibition. Notwithstanding, potent PIN1 inhibitors are still missing from the arsenal of anti-cancer drugs. By a mechanism-based screening, we have identified a novel covalent PIN1 inhibitor, KPT-6566, able to selectively inhibit PIN1 and target it for degradation. We demonstrate that KPT-6566 covalently binds to the catalytic site of PIN1. This interaction results in the release of a quinone-mimicking drug that generates reactive oxygen species and DNA damage, inducing cell death specifically in cancer cells. Accordingly, KPT-6566 treatment impairs PIN1-dependent cancer phenotypes in vitro and growth of lung metastasis in vivo.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Urusova, Darya V.; Shim, Jung-Hyun; Kim, Dong Joon
The most active anticancer component in green tea is epigallocatechin-3-gallate (EGCG). The human peptidyl prolyl cis/trans isomerase (Pin1) plays a critical role in oncogenic signaling. Herein, we report the X-ray crystal structure of the Pin1/EGCG complex resolved at 1.9 Å resolution. Notably, the structure revealed the presence of EGCG in both the WW and PPIase domains of Pin1. The direct binding of EGCG with Pin1 was confirmed and the interaction inhibited Pin1 PPIase activity. In addition, proliferation of cells expressing Pin1 was inhibited and tumor growth in a xenograft mouse model was suppressed. The binding of EGCG with Arg17 inmore » the WW domain prevented the binding of c-Jun, a well-known Pin1 substrate. EGCG treatment corresponded with a decreased abundance of cyclin D1 and diminution of 12-O-tetradecanoylphorbol-l3-acetate–induced AP-1 or NF-κB promoter activity in cells expressing Pin1. Overall, these results showed that EGCG directly suppresses the tumor-promoting effect of Pin1.« less
Lian, Xiaolan; Lin, Yu-Min; Kozono, Shingo; Herbert, Megan K; Li, Xin; Yuan, Xiaohong; Guo, Jiangrui; Guo, Yafei; Tang, Min; Lin, Jia; Huang, Yiping; Wang, Bixin; Qiu, Chenxi; Tsai, Cheng-Yu; Xie, Jane; Cao, Ziang Jeff; Wu, Yong; Liu, Hekun; Zhou, Xiaozhen; Lu, Kunping; Chen, Yuanzhong
2018-05-30
The increasing genomic complexity of acute myeloid leukemia (AML), the most common form of acute leukemia, poses a major challenge to its therapy. To identify potent therapeutic targets with the ability to block multiple cancer-driving pathways is thus imperative. The unique peptidyl-prolyl cis-trans isomerase Pin1 has been reported to promote tumorigenesis through upregulation of numerous cancer-driving pathways. Although Pin1 is a key drug target for treating acute promyelocytic leukemia (APL) caused by a fusion oncogene, much less is known about the role of Pin1 in other heterogeneous leukemia. The mRNA and protein levels of Pin1 were detected in samples from de novo leukemia patients and healthy controls using real-time quantitative RT-PCR (qRT-PCR) and western blot. The establishment of the lentiviral stable-expressed short hairpin RNA (shRNA) system and the tetracycline-inducible shRNA system for targeting Pin1 were used to analyze the biological function of Pin1 in AML cells. The expression of cancer-related Pin1 downstream oncoproteins in shPin1 (Pin1 knockdown) and Pin1 inhibitor all-trans retinoic acid (ATRA) treated leukemia cells were examined by western blot, followed by evaluating the effects of genetic and chemical inhibition of Pin1 in leukemia cells on transformed phenotype, including cell proliferation and colony formation ability, using trypan blue, cell counting assay, and colony formation assay in vitro, as well as the tumorigenesis ability using in vivo xenograft mouse models. First, we found that the expression of Pin1 mRNA and protein was significantly increased in both de novo leukemia clinical samples and multiple leukemia cell lines, compared with healthy controls. Furthermore, genetic or chemical inhibition of Pin1 in human multiple leukemia cell lines potently inhibited multiple Pin1 substrate oncoproteins and effectively suppressed leukemia cell proliferation and colony formation ability in cell culture models in vitro. Moreover, tetracycline-inducible Pin1 knockdown and slow-releasing ATRA potently inhibited tumorigenicity of U937 and HL-60 leukemia cells in xenograft mouse models. We demonstrate that Pin1 is highly overexpressed in human AML and is a promising therapeutic target to block multiple cancer-driving pathways in AML.
Water flow and fin shape polymorphism in coral reef fishes.
Binning, Sandra A; Roche, Dominique G
2015-03-01
Water flow gradients have been linked to phenotypic differences and swimming performance across a variety of fish assemblages. However, the extent to which water motion shapes patterns of phenotypic divergence within species remains unknown. We tested the generality of the functional relationship between swimming morphology and water flow by exploring the extent of fin and body shape polymorphism in 12 widespread species from three families (Acanthuridae, Labridae, Pomacentridae) of pectoral-fin swimming (labriform) fishes living across localized wave exposure gradients. The pectoral fin shape of Labridae and Acanthuridae species was strongly related to wave exposure: individuals with more tapered, higher aspect ratio (AR) fins were found on windward reef crests, whereas individuals with rounder, lower AR fins were found on leeward, sheltered reefs. Three of seven Pomacentridae species showed similar trends, and pectoral fin shape was also strongly related to wave exposure in pomacentrids when fin aspect ratios of three species were compared across flow habitats at very small spatial scales (<100 m) along a reef profile (reef slope, crest, and back lagoon). Unlike fin shape, there were no intraspecific differences in fish body fineless ratio across habitats or depths. Contrary to our predictions, there was no pattern relating species' abundances to polymorphism across habitats (i.e., abundance was not higher at sites where morphology is better adapted to the environment). This suggests that there are behavioral and/or physiological mechanisms enabling some species to persist across flow habitats in the absence of morphological differences. We suggest that functional relationships between swimming morphology and water flow not only structure species assemblages, but are yet another important variable contributing to phenotypic differences within species. The close links between fin shape polymorphism and local water flow conditions appear to be important for understanding species' distributions as well as patterns of diversification across environmental gradients.
Zhang, X; Shimoda, K; Ura, K; Adachi, S; Takagi, Y
2012-11-01
In the larval bester, a hybrid sturgeon of beluga Huso huso and sterlet Acipenser ruthenus, development of cartilage around the notochord began 7 days post hatch (dph) (14.0 mm, total length, L(T)). The vertebral cartilage develops in the following sequence: basidorsals and basiventrals, neural canals, neural spines and ribs. The development of ribs remained incomplete in the largest specimen (181 dph, 179 mm L(T) ) that was examined. Endoskeletal development of the fins began 4 dph for the dorsal and anal fins, 6 dph for the pectoral fin and 10 dph for the caudal and pelvic fins. Complete elements of all fins were observed by 91 dph and complete ossification of fin rays was observed by 122 dph in the double-stained specimens. Observation of the histological sections, however, suggested that ossification occurred soon after the formation of the organic matrix in the fin rays. Dorsal scutes were first visible by 25 dph, followed by the lateral and ventral scutes, which were visible by 37 and 44 dph, respectively. The number of scutes was fixed at 44, 59 and 91 dph and ossification was complete by 59 (dorsal) and 91 dph (lateral and ventral scutes) in the double-stained specimens. Ossification occurred soon after the formation of the scute organic matrix in the histological sections. Four types of scales were observed in the H. huso×A. ruthenus hybrid. Median predorsal, preanal and small scales on the anterior section of the head were visible by 59 dph. Scales on the caudal fin were visible by 91 dph and a variable assemblage of scales anterior to the anal fin was visible by 122 dph. Both the scutes and scales developed in a process that is similar to that of intramembranous ossification. © 2012 The Authors. Journal of Fish Biology © 2012 The Fisheries Society of the British Isles.
Performance ‘S’ Type Savonius Wind Turbine with Variation of Fin Addition on Blade
NASA Astrophysics Data System (ADS)
Pamungkas, S. F.; Wijayanto, D. S.; Saputro, H.; Widiastuti, I.
2018-01-01
Wind power has been receiving attention as the new energy resource in addressing the ecological problems of burning fossil fuels. Savonius wind rotor is a vertical axis wind turbines (VAWT) which has relatively simple structure and low operating speed. These characteristics make it suitable for areas with low average wind speed as in Indonesia. To identify the performance of Savonius rotor in generating electrical energy, this research experimentally studied the effect of fin addition for the ‘S’ shape of Savonius VAWT. The fin is added to fill the space in the blade in directing the wind flow. This rotor has two turbine blades, a rotor diameter of 1.1 m and rotor height of 1.4 m, used pulley transmission system with 1:4.2 multiplication ratio, and used a generator type PMG 200 W. The research was conducted during dry season by measuring the wind speed in the afternoon. The average wind speed in the area is 2.3 m/s with the maximum of 4.5 m/s. It was found that additional fin significantly increase the ability of Savonius rotor VAWT to generate electrical energy shown by increasing of electrical power. The highest power generated is 13.40 Watt at a wind speed of 4.5 m/s by adding 1 (one) fin in the blade. It increased by 22.71% from the rotor blade with no additional fin. However, increasing number of fins in the blade was not linearly increase the electrical power generated. The wind rotor blade with 4 additional fins is indicated has the lowest performance, generating only 10.80 Watt electrical power, accounted lower than the one generated by no fin-rotor blade. By knowing the effect of the rotor shape, the rotor dimension, the addition of fin, transmission, and generator used, it is possible to determine alternative geometry design in increasing the electrical power generated by Savonius wind turbine.
Fish biorobotics: kinematics and hydrodynamics of self-propulsion.
Lauder, George V; Anderson, Erik J; Tangorra, James; Madden, Peter G A
2007-08-01
As a result of years of research on the comparative biomechanics and physiology of moving through water, biologists and engineers have made considerable progress in understanding how animals moving underwater use their muscles to power movement, in describing body and appendage motion during propulsion, and in conducting experimental and computational analyses of fluid movement and attendant forces. But it is clear that substantial future progress in understanding aquatic propulsion will require new lines of attack. Recent years have seen the advent of one such new avenue that promises to greatly broaden the scope of intellectual opportunity available to researchers: the use of biorobotic models. In this paper we discuss, using aquatic propulsion in fishes as our focal example, how using robotic models can lead to new insights in the study of aquatic propulsion. We use two examples: (1) pectoral fin function, and (2) hydrodynamic interactions between dorsal and caudal fins. Pectoral fin function is characterized by considerable deformation of individual fin rays, as well as spanwise (along the length) and chordwise (across the fin) deformation and area change. The pectoral fin can generate thrust on both the outstroke and instroke. A robotic model of the pectoral fin replicates this result, and demonstrates the effect of altering stroke kinematics on the pattern of force production. The soft dorsal fin of fishes sheds a distinct vortex wake that dramatically alters incoming flow to the tail: the dorsal fin and caudal fin act as dual flapping foils in series. This design can be replicated with a dual-foil flapping robotic device that demonstrates this phenomenon and allows examination of regions of the flapping performance space not available to fishes. We show how the robotic flapping foil device can also be used to better understand the significance of flexible propulsive surfaces for locomotor performance. Finally we emphasize the utility of self-propelled robotic devices as a means of understanding how locomotor forces are generated, and review different conceptual designs for robotic models of aquatic propulsion.
The fish fauna of Anambra river basin, Nigeria: species abundance and morphometry.
Odo, Gregory Ejikeme; Didigwu, Nwani Christopher; Eyo, Joseph Effiong
2009-01-01
The fish yields of most Nigeria inland waters are generally on the decline for causes that may range from inadequate management of the fisheries to degradation of the water bodies. Sustainable exploitation requires knowledge of the ichthyofaunal composition in the water bodies. We did a survey of fish species in Anambra river basin for 22 months. Fish samples were collected using four different gears -hook and line of size 13, caste nets, gill nets, and cages of mesh sizes of 50 mm, 75 mm, and 100 mm each. We recorded 52 fish species belonging to 17 families: 171, 236, and 169 individuals at Ogurugu, Otuocha, and Nsugbe stations respectively. Two families, Characidae, 19.5%, and Mochokidae, 11.8%, constituted the dominant fish families in the river. The dominant fish species were Citherinus citherius, 9.02%, and Alestes nurse, 7.1%. Other fish species with significant abundance were Synodontis clarias 6.9%, Macrolepidotus curvier 5.7%, Labeo coubie 5.4%, Distichodus rostrtus 4.9%, and Schilbe mystus 4.5%. The meristic features of the two most abundant fish species caught are as follows: Citharinus citharius dorsal fins 20, anal fins 30, caudal fins 21, pectoral fins, 9 and 8 ventral fins, and Alestes nurse 10 dorsal fins, 14 anal fins, 31 caudal fins, 7 pectoral fins and 6 ventral fins. The morphometric features of the two most abundant fish species are Citharinus citharius total length 300 mm, standard length 231 mm, head length 69 mm, body length 101 mm, body girth 176 mm, body weight 900 mg. Alestes nurse total length 200, standard length 140 mm, head length 60 mm, body length 80 mm, body girth 120 mm, body weight 400 mg. The most abundant animal utilizing the basin was Ardea cinerea (D3) with 22.2% occurrence (D4) and this was followed by Caprini with 13.51%, and Varanus niloticus, 10.04%. The least abundant animals utilizing basin were Chephalophus rufilatus, and Erythrocebus patas, with 0.58% each of occurrence.
Visualization of an air-water interface on superhydrophobic surfaces in turbulent channel flows
NASA Astrophysics Data System (ADS)
Kim, Hyunseok; Park, Hyungmin
2017-11-01
In the present study, three-dimensional deformation of air-water interface on superhydrophobic surfaces in turbulent channel flows at the Reynolds numbers of Re = 3000 and 10000 is measured with RICM (Reflection Interference Contrast Microscopy) technique. Two different types of roughness feature of circular hole and rectangular grate are considered, whose depth is 20 μm and diameter (or width) is varied between 20-200 μm. Since the air-water interface is always at de-pinned state at the considered condition, air-water interface shape and its sagging velocity is maintained to be almost constant as time goes one. In comparison with the previous results under the laminar flow, due to turbulent characteristics of the flow, sagging velocity is much faster. Based on the measured sagging profiles, a modified model to describe the air-water interface dynamics under turbulent flows is suggested. Supported by City of Seoul through Seoul Urban Data Science Laboratory Project (Grant No 0660-20170004) administered by SNU Big Data Institute.
Electric Field Controlled Magnetism in BiFeO3/Ferromagnet Films
NASA Astrophysics Data System (ADS)
Holcomb, M. B.; Chu, Y. H.; Martin, L. W.; Gajek, M.; Seidel, J.; Ramesh, R.; Scholl, A.; Fraile-Rodriguez, A.
2008-03-01
Electric field control of magnetism is a hot technological topic at the moment due to its potential to revolutionize today's devices. Magnetoelectric materials, those having both electric and magnetic order and the potential for coupling between the two, are a promising avenue to approach electric control. BiFeO3, both a ferroelectric and an antiferromagnet, is the only single phase room temperature magnetoelectric that is currently known. In addition to other possibilities, its multiferroic nature has potential in the very active field of exchange bias, where an antiferromagnetic thin film pins the magnetic direction of an adjoining ferromagnetic layer. Since this antiferromagnet is electrically tunable, this coupling could allow electric-field control of the ferromagnetic magnetization. Direction determination of antiferromagnetic domains in BFO has recently been shown using linear and circular dichroism studies. Recently, this technique has been extended to look at the magnetic domains of a ferromagnetic grown on top of BFO. The clear magnetic changes induced by application of electric fields reveal the possibility of electric control.
Transmission XMCD-PEEM imaging of an engineered vertical FEBID cobalt nanowire with a domain wall
NASA Astrophysics Data System (ADS)
Wartelle, A.; Pablo-Navarro, J.; Staňo, M.; Bochmann, S.; Pairis, S.; Rioult, M.; Thirion, C.; Belkhou, R.; de Teresa, J. M.; Magén, C.; Fruchart, O.
2018-01-01
Using focused electron-beam-induced deposition, we fabricate a vertical, platinum-coated cobalt nanowire with a controlled three-dimensional structure. The latter is engineered to feature bends along the height: these are used as pinning sites for domain walls, which are obtained at remanence after saturation of the nanostructure in a horizontally applied magnetic field. The presence of domain walls is investigated using x-ray magnetic circular dichroism (XMCD) coupled to photoemission electron microscopy (PEEM). The vertical geometry of our sample combined with the low incidence of the x-ray beam produce an extended wire shadow which we use to recover the wire’s magnetic configuration. In this transmission configuration, the whole sample volume is probed, thus circumventing the limitation of PEEM to surfaces. This article reports on the first study of magnetic nanostructures standing perpendicular to the substrate with XMCD-PEEM. The use of this technique in shadow mode enabled us to confirm the presence of a domain wall without direct imaging of the nanowire.
NASA Astrophysics Data System (ADS)
Liu, Ya; Kuksenok, Olga; Bhattacharya, Amitabh; Ma, Yongting; He, Ximin; Aizenberg4, Joanna; Balazs, Anna
2014-03-01
In biomimetics, designing an effective ``catch and release'' device for the selective removal of target species from the surrounding solution is critical for developing autonomous sensors and sorters. Using computer simulations, we model an array of oscillating fins that are tethered on the floor of a microchannel and immersed in a mixture of binary fluid stream and binary nanoparticles. During the oscillation, the fins with the specific chemical wetting reach the upper fluid when they are upright and are entirely immersed within the lower stream when they are tilted. We introduce specific interaction between the fins and particulates in the solution and determine conditions where the oscillating fins can selectively ?catch? target nanoparticles within the upper fluid stream and then release these particles into the lower stream. We isolate the effects of wetting contact angle between fins and fluid and the mode of fins' oscillations that lead to the efficient extraction of target species from the upper stream and their placement into the lower fluid. These studies provide fundamental insights into the system's complex dynamics and mechanism for detection, separation, and purification of multi-component mixtures.
Effect of pectoral fin kinematics on manta ray propulsion
NASA Astrophysics Data System (ADS)
Lu, Hao; Yeo, Khoon Seng; Chew, Chee-Meng
2018-05-01
Recent advancement of bio-inspired underwater vehicles has led to a growing interest in understanding the fluid mechanics of fish locomotion, which involves complex interaction between the deforming structure and its surrounding fluid. Unlike most natural swimmers that undulate their body and caudal fin, manta rays employ an oscillatory mode by flapping their large, flattened pectoral fins to swim forward. Such a lift-based mode can achieve a substantially high propulsive efficiency, which is beneficial to long-distance swimming. In this study, numerical simulations are carried out on a realistic manta ray model to investigate the effect of pectoral fin kinematics on the propulsive performance and flow structure. A traveling wave model, which relates a local deflection angle to radial and azimuthal wavelengths, is applied to generate the motion of the pectoral fins. Hydrodynamic forces and propulsive efficiency are reported for systematically varying kinematic parameters such as wave amplitude and wavelengths. Key flow features, including a leading edge vortex (LEV) that forms close to the tip of each pectoral fin, and a wake consisting of interconnected vortex rings, are identified. In addition, how different fin motions alter the LEV behavior and hence affect the thrust and efficiency is illustrated.
Slotting Fins of Heat Exchangers to Provide Thermal Breaks
NASA Technical Reports Server (NTRS)
Scull, Timothy D.
2003-01-01
Heat exchangers that include slotted fins (in contradistinction to continuous fins) have been invented. The slotting of the fins provides thermal breaks that reduce thermal conduction along flow paths (longitudinal thermal conduction), which reduces heat-transfer efficiency. By increasing the ratio between transverse thermal conduction (the desired heat-transfer conduction) and longitudinal thermal conduction, slotting of the fins can be exploited to (1) increase heat-transfer efficiency (thereby reducing operating cost) for a given heat-exchanger length or to (2) reduce the length (thereby reducing the weight and/or cost) of the heat exchanger needed to obtain a given heat transfer efficiency. By reducing the length of a heat exchanger, one can reduce the pressure drop associated with the flow through it. In a case in which slotting enables the use of fins with thermal conductivity greater than could otherwise be tolerated on the basis of longitudinal thermal conduction, one can exploit the conductivity to make the fins longer (in the transverse direction) than they otherwise could be, thereby making it possible to make a heat exchanger that contains fewer channels and therefore, that weighs less, contains fewer potential leak paths, and can be constructed from fewer parts and, hence, reduced cost.
NASA Astrophysics Data System (ADS)
Hartmann, Jana; Steib, Frederik; Zhou, Hao; Ledig, Johannes; Nicolai, Lars; Fündling, Sönke; Schimpke, Tilman; Avramescu, Adrian; Varghese, Tansen; Trampert, Achim; Straßburg, Martin; Lugauer, Hans-Jürgen; Wehmann, Hergo-Heinrich; Waag, Andreas
2017-10-01
GaN fins are 3D architectures elongated in one direction parallel to the substrate surface. They have the geometry of walls with a large height to width ratio as well as small footprints. When appropriate symmetry directions of the GaN buffer are used, the sidewalls are formed by non-polar {1 1 -2 0} planes, making the fins particularly suitable for many device applications like LEDs, FETs, lasers, sensors or waveguides. The influence of growth parameters like temperature, pressure, V/III ratio and total precursor flow on the fin structures is analyzed. Based on these results, a 2-temperature-step-growth was developed, leading to fins with smooth side and top facets, fast vertical growth rates and good homogeneity along their length as well as over different mask patterns. For the core-shell growth of fin LED heterostructures, the 2-temperature-step-growth shows much smoother sidewalls and less crystal defects in the InGaN QW and p-GaN shell compared to structures with cores grown in just one step. Electroluminescence spectra of the 2-temperature-step-grown fin LED are demonstrated.
beam diameter? Which ion beams are available and how long does it take to change from one to another connector is inverted. Adapters are available to invert the pins again resulting in a one-to-one pin pattern one-to-one pin pattern. Maximim current rating is 1 amp per pin. Five 37-pin D subminiature connectors
NASA Technical Reports Server (NTRS)
Hyer, M. W.; Klang, E. C.; Cooper, D. E.
1987-01-01
The effects of pin elasticity, clearance, and friction on the stresses in a pin loaded orthotropic plate are studied. The effects are studied by posing the problem as a planar contact elasticity problem, the pin and the plate being two elastic bodies which interact through contact. Coulomb friction is assumed, the pin loads the plate in one of its principal material directions, and the plate is infinite in extent. A collocation scheme and interaction, in conjunction with a complex variable series solution, are used to obtain numerical results. The contact region between the plate and pin is unknown and must be solved for as part of the solution. The same is true of the region of friction induced no slip. Two pin stiffnesses, two clearance levels, two friction levels and two laminates, a (0/+ or - 45/90)s and a (02/+ or - 45)s, are studied. The effects of pin elasticity, clearance, and friction on the load capacity of the plate are assessed by comparing the load capacity of the plate with the capacity when the pin is rigid, perfectly fitting, and frictionless.
Wei, Shuo; Kozono, Shingo; Kats, Lev; Nechama, Morris; Li, Wenzong; Guarnerio, Jlenia; Luo, Manli; You, Mi-Hyeon; Yao, Yandan; Kondo, Asami; Hu, Hai; Bozkurt, Gunes; Moerke, Nathan J; Cao, Shugeng; Reschke, Markus; Chen, Chun-Hau; Rego, Eduardo M; Lo-Coco, Francesco; Cantley, Lewis C; Lee, Tae Ho; Wu, Hao; Zhang, Yan; Pandolfi, Pier Paolo; Zhou, Xiao Zhen; Lu, Kun Ping
2015-05-01
A common key regulator of oncogenic signaling pathways in multiple tumor types is the unique isomerase Pin1. However, available Pin1 inhibitors lack the required specificity and potency for inhibiting Pin1 function in vivo. By using mechanism-based screening, here we find that all-trans retinoic acid (ATRA)--a therapy for acute promyelocytic leukemia (APL) that is considered the first example of targeted therapy in cancer, but whose drug target remains elusive--inhibits and degrades active Pin1 selectively in cancer cells by directly binding to the substrate phosphate- and proline-binding pockets in the Pin1 active site. ATRA-induced Pin1 ablation degrades the protein encoded by the fusion oncogene PML-RARA and treats APL in APL cell and animal models as well as in human patients. ATRA-induced Pin1 ablation also potently inhibits triple-negative breast cancer cell growth in human cells and in animal models by acting on many Pin1 substrate oncogenes and tumor suppressors. Thus, ATRA simultaneously blocks multiple Pin1-regulated cancer-driving pathways, an attractive property for treating aggressive and drug-resistant tumors.
Biomechanical and Cost Comparisons of Near-Far and Pin-Bar Constructs.
Whitney Kluk, Augusta; Zhang, Tina; Russell, Joseph P; Kim, Hyunchul; Hsieh, Adam H; O'Toole, Robert V
2017-03-01
Orthopedic dogma states that external fixator stiffness is improved by placing 1 pin close to the fracture and 1 as distant as possible ("near-far"). This fixator construct is thought to be less expensive than placing pins a shorter distance apart and using "pin-bar" clamps that attach pins to outriggers. The authors therefore hypothesized that the near-far construct is stiffer and less expensive. They compared mechanical stiffness and costs of near-far and pin-bar constructs commonly used for temporary external fixation of femoral shaft fractures. Their testing model simulated femoral shaft fractures in damage control situations. Fourth-generation synthetic femora (n=18) were used. The near-far construct had 2 pins that were 106 mm apart, placed 25 mm from the gap on each side of the fracture. The pin-bar construct pins were 55 mm apart, placed 40 mm from the gap. Mechanical testing was performed on a material test system machine. Stiffness was determined in the linear portion of the load-displacement curve for both constructs in 4 modes: axial compression, torsional loading, frontal plane 3-point bending, and sagittal plane 3-point bending. Costs were determined from a 2012 price guide. Compared with the near-far construct, the pin-bar construct had stiffness increased by 58% in axial compression (P<.05) and by 52% in torsional loading (P<.05). The pin-bar construct increased cost by 11%. In contrast to the authors' hypothesis and existing orthopedic dogma, the near-far construct was less stiff than the pin-bar construct and was similarly priced. Use of the pin-bar construct is mechanically and economically reasonable. [Orthopedics. 2017; 40(2):e238-e241.]. Copyright 2016, SLACK Incorporated.
Giroux, Michael J.; Morris, Craig F.
1998-01-01
“Soft” and “hard” are the two main market classes of wheat (Triticum aestivum L.) and are distinguished by expression of the Hardness gene. Friabilin, a marker protein for grain softness (Ha), consists of two proteins, puroindoline a and b (pinA and pinB, respectively). We previously demonstrated that a glycine to serine mutation in pinB is linked inseparably to grain hardness. Here, we report that the pinB serine mutation is present in 9 of 13 additional randomly selected hard wheats and in none of 10 soft wheats. The four exceptional hard wheats not containing the serine mutation in pinB express no pinA, the remaining component of the marker protein friabilin. The absence of pinA protein was linked inseparably to grain hardness among 44 near-isogenic lines created between the soft variety Heron and the hard variety Falcon. Both pinA and pinB apparently are required for the expression of grain softness. The absence of pinA protein and transcript and a glycine-to-serine mutation in pinB are two highly conserved mutations associated with grain hardness, and these friabilin genes are the suggested tightly linked components of the Hardness gene. A previously described grain hardness related gene termed “GSP-1” (grain softness protein) is not controlled by chromosome 5D and is apparently not involved in grain hardness. The association of grain hardness with mutations in both pinA or pinB indicates that these two proteins alone may function together to effect grain softness. Elucidation of the molecular basis for grain hardness opens the way to understanding and eventually manipulating this wheat endosperm property. PMID:9600953
Sturges, Beverly K; Kapatkin, Amy S; Garcia, Tanya C; Anwer, Cona; Fukuda, Shimpei; Hitchens, Peta L; Wisner, Tristan; Hayashi, Kei; Stover, Susan M
2016-04-01
To compare the stiffness, angular deformation, and mode of failure of lumbar vertebral column constructs stabilized with bilateral pins and polymethylmethacrylate (Pin-PMMA) or with a unilateral (left) locking compression plate (LCP) with monocortical screws. Ex vivo biomechanical, non-randomized. Cadaveric canine thoracolumbar specimens (n=16). Thoracolumbar (T13-L3) vertebral specimens had the L1-L2 vertebral motion unit stabilized with either Pin-PMMA or LCP. Stiffness in flexion, extension, and right and left lateral bending after nondestructive testing were compared between intact (pretreated) specimens and Pin-PMMA, and LCP constructs. The Pin-PMMA and LCP constructs were then tested to failure in flexion and left lateral bending. Both the Pin-PMMA and LCP constructs had reduced range of motion at the stabilized L1-L2 vertebral motion unit compared to intact specimens. The Pin-PMMA constructs had less range of motion for the flexion elastic zone than LCP constructs. The Pin-PMMA constructs were stiffer than intact specimens in flexion, extension, and lateral bending, and stiffer than LCP constructs in flexion and left lateral bending. The Pin-PMMA constructs had less angular deformation at construct yield and lower residual deformation at L1-L2 than LCP constructs after destructive testing to failure in flexion. The Pin-PMMA constructs were stiffer, stronger, and had less deformation at yield than LCP constructs after destructive testing to failure in lateral bending. Most constructs failed distant to the implant and fixation site. Pin-PMMA constructs had greater lumbar vertebral stiffness and reduced ROM than LCP constructs; however, both Pin-PMMA and LCP constructs were stronger than intact specimens. © Copyright 2016 by The American College of Veterinary Surgeons.
Chanana, Mitin; Kumar, Adarsh; Tyagi, Som Prakash; Singla, Amit Kumar; Sharma, Arvind; Farooq, Uiase Bin
2018-02-01
The current study was undertaken to evaluate the clinical efficacy of end-threaded intramedullary pinning for management of various long bone fractures in canines. This study was conducted in two phases, managing 25 client-owned dogs presented with different fractures. The technique of application of end-threaded intramedullary pinning in long bone fractures was initially standardized in 6 clinical patients presented with long bone fractures. In this phase, end-threaded pins of different profiles, i.e., positive and negative, were used as the internal fixation technique. On the basis of results obtained from standardization phase, 19 client-owned dogs clinically presented with different fractures were implanted with end-threaded intramedullary positive profile screw ended self-tapping pin in the clinical application phase. The patients, allocated randomly in two groups, when evaluated postoperatively revealed slight pin migration in Group-I (negative profile), which resulted in disruption of callus site causing delayed union in one case and large callus formation in other two cases whereas no pin migration was observed in Group-II (positive profile). Other observations in Group-I was reduced muscle girth and delayed healing time as compared to Group-II. In clinical application, phase 21 st and 42 nd day post-operative radiographic follow-up revealed no pin migration in any of the cases, and there was no bone shortening or fragment collapse in end-threaded intramedullary positive profile screw ended self-tapping pin. The end-threaded intramedullary positive profile screw ended self-tapping pin used for fixation of long bone fractures in canines can resist pin migration, pin breakage, and all loads acting on the bone, i.e., compression, tension, bending, rotation, and shearing to an extent with no post-operative complications.
Foolproof quick-release locking pin
NASA Technical Reports Server (NTRS)
Nelson, E. P.; Othman, T. E.; Zmuda, L. J.
1970-01-01
Locking pin can be withdrawn only when stress on the joint is negligible. Pin consists of a forward-pointing sleeve, a spring-loaded sliding handle, and a sliding plunger. Plunger movement controls installation and withdrawal of pin.
NASA Astrophysics Data System (ADS)
Pech-Canul, M. A.; Guía-Tello, J. C.; Pech-Canul, M. I.; Aguilar, J. C.; Gorocica-Díaz, J. A.; Arana-Guillén, R.; Puch-Bleis, J.
An aluminum automotive condenser was designed to exhibit high corrosion resistance in the seawater acetic acid test (SWAAT) combining zinc coated microchannel tubes and fins made with AA4343/AA3003(Zn)/AA4343 brazing sheet. Electrochemical measurements in SWAAT solution were carried out under laboratory conditions using tube-fin assembly and individual fin and tube samples withdrawn from the condenser core. The aim was to gain information on the protective role of the zinc sacrificial layer and about changes in corrosion behavior as a function of immersion time. External corrosion of the tube-fin system was simulated by immersion of mini-core samples under open circuit conditions. The corrosion rate increased rapidly during the first 6 h and slowly afterwards. The short time behavior was related to the dissolution of the oxide film and fast dissolution of the outermost part of the zinc diffusion layer. With the aid of cross-sectional depth corrosion potential profiles, it was shown that as the sacrificial layer gets dissolved, the surface concentration of zinc decreases and the potential shifts to less negative values. The results of galvanic coupling of tube and fins in a mini-cell showed that the tube became the anode while the fins exhibited cathodic behavior. An evolution in the galvanic interaction was observed, due to the progressive dissolution of the sacrificial zinc layer. The difference of uncoupled potentials between tube and fins decreased from 71 mV to 32 mV after 84 h of galvanic coupling. At the end of such period there was still a part of the zinc sacrificial layer remaining which would serve for protection of the tube material for even longer periods and there were indications of slight corrosion in the fins.
Ren, Ziyu; Yang, Xingbang; Wang, Tianmiao; Wen, Li
2016-02-08
Recent advances in understanding fish locomotion with robotic devices have included the use of biomimetic flapping based and fin undulatory locomotion based robots, treating two locomotions separately from each other. However, in most fish species, patterns of active movements of fins occur in concert with the body undulatory deformation during swimming. In this paper, we describe a biomimetic robotic caudal fin programmed with individually actuated fin rays to mimic the fin motion of the Bluegill Sunfish (Lepomis macrochirus) and coupled with heave and pitch oscillatory motions adding to the robot to mimic the peduncle motion which is derived from the undulatory fish body. Multiple-axis force and digital particle image velocimetry (DPIV) experiments from both the vertical and horizontal planes behind the robotic model were conducted under different motion programs and flow speeds. We found that both mean thrust and lift could be altered by changing the phase difference (φ) from 0° to 360° between the robotic caudal peduncle and the fin ray motion (spanning from 3 mN to 124 mN). Notably, DPIV results demonstrated that the caudal fin generated multiple wake flow patterns in both the vertical and horizontal planes by varying φ. Vortex jet angle and thrust impulse also varied significantly both in these two planes. In addition, the vortex shedding position along the spanwise tail direction could be shifted around the mid-sagittal position between the upper and lower lobes by changing the phase difference. We hypothesize that the fish caudal fin may serve as a flexible vectoring propeller during swimming and may be critical for the high maneuverability of fish.
Wind Fins: Novel Lower-Cost Wind Power System
DOE Office of Scientific and Technical Information (OSTI.GOV)
David C. Morris; Dr. Will D. Swearingen
This project evaluated the technical feasibility of converting energy from the wind with a novel “wind fin” approach. This patent-pending technology has three major components: (1) a mast, (2) a vertical, hinged wind structure or fin, and (3) a power takeoff system. The wing structure responds to the wind with an oscillating motion, generating power. The overall project goal was to determine the basic technical feasibility of the wind fin technology. Specific objectives were the following: (1) to determine the wind energy-conversion performance of the wind fin and the degree to which its performance could be enhanced through basic designmore » improvements; (2) to determine how best to design the wind fin system to survive extreme winds; (3) to determine the cost-effectiveness of the best wind fin designs compared to state-of-the-art wind turbines; and (4) to develop conclusions about the overall technical feasibility of the wind fin system. Project work involved extensive computer modeling, wind-tunnel testing with small models, and testing of bench-scale models in a wind tunnel and outdoors in the wind. This project determined that the wind fin approach is technically feasible and likely to be commercially viable. Project results suggest that this new technology has the potential to harvest wind energy at approximately half the system cost of wind turbines in the 10kW range. Overall, the project demonstrated that the wind fin technology has the potential to increase the economic viability of small wind-power generation. In addition, it has the potential to eliminate lethality to birds and bats, overcome public objections to the aesthetics of wind-power machines, and significantly expand wind-power’s contribution to the national energy supply.« less
The incidence of bent dorsal fins in free-ranging cetaceans.
Alves, F; Towers, J R; Baird, R W; Bearzi, G; Bonizzoni, S; Ferreira, R; Halicka, Z; Alessandrini, A; Kopelman, A H; Yzoard, C; Rasmussen, M H; Bertulli, C G; Jourdain, E; Gullan, A; Rocha, D; Hupman, K; Mrusczok, M-T; Samarra, F I P; Magalhães, S; Weir, C R; Ford, J K B; Dinis, A
2018-02-01
Laterally bent dorsal fins are rarely observed in free-ranging populations of cetaceans, contrary to captivity, where most killer whale Orcinus orca adult males have laterally collapsed fins. This topic has been poorly explored, and data/information on its occurrence and possible causes are limited. The present study: (i) undertakes a review of the available information on bent dorsal fins in free-ranging cetaceans, and updates it with new records, (ii) reports on the proportion of bent fins in different study populations, and (iii) discusses possible causes. An empirical approach based on bibliographic research and compilation of 52 new records collected worldwide resulted in a total of 17 species of cetaceans displaying bent dorsal fins. The species with the highest number of records (64%) and from most locations was O. orca. On average, individuals with bent dorsal fins represent < 1% of their populations, with the exception of false killer whales Pseudorca crassidens and O. orca. While line injuries associated with fisheries interactions may be the main cause for P. crassidens, and the vulnerability to health issues caused by the evolutionary enlargement of the fin may be the cause for O. orca adult males, factors contributing to this abnormality for other species are still unclear. The occurrence of bent dorsals could be influenced by a set of variables rather than by a single factor but, irrespective of the cause, it is suggested that it does not directly affect the animals' survivorship. While still rare in nature, this incident is more common (at least 101 known cases) and widespread (geographically and in species diversity) than hypothesized, and is not confined only to animals in captive environments. Investigation into the occurrence of bent fins may be an interesting avenue of research. © 2017 Anatomical Society.
The heartstrings mutation in zebrafish causes heart/fin Tbx5 deficiency syndrome.
Garrity, Deborah M; Childs, Sarah; Fishman, Mark C
2002-10-01
Holt-Oram syndrome is one of the autosomal dominant human "heart-hand" disorders, with a combination of upper limb malformations and cardiac defects. Holt-Oram syndrome is caused by mutations in the TBX5 gene, a member of a large family of T-box transcription factors that play important roles in cell-type specification and morphogenesis. In a screen for mutations affecting zebrafish cardiac function, we isolated the recessive lethal mutant heartstrings, which lacks pectoral fins and exhibits severe cardiac dysfunction, beginning with a slow heart rate and progressing to a stretched, non-functional heart. We mapped and cloned the heartstrings mutation and find it to encode the zebrafish ortholog of the TBX5 gene. The heartstrings mutation causes premature termination at amino acid 316. Homozygous mutant embryos never develop pectoral fin buds and do not express several markers of early fin differentiation. The total absence of any fin bud differentiation distinguishes heartstrings from most other mutations that affect zebrafish fin development, suggesting that Tbx5 functions very early in the pectoral fin induction pathway. Moderate reduction of Tbx5 by morpholino causes fin malformations, revealing an additional early requirement for Tbx5 in coordinating the axes of fin outgrowth. The heart of heartstrings mutant embryos appears to form and function normally through the early heart tube stage, manifesting only a slight bradycardia compared with wild-type siblings. However, the heart fails to loop and then progressively deteriorates, a process affecting the ventricle as well as the atrium. Relative to mammals, fish require lower levels of Tbx5 to produce malformed appendages and display whole-heart rather than atrial-predominant cardiac defects. However, the syndromic deficiencies of tbx5 mutation are remarkably well retained between fish and mammals.
NASA Technical Reports Server (NTRS)
Henning, Allen B.
1959-01-01
Two rocket-propelled missiles have been test flown by the Langley Pilotless Aircraft Research Division in order to study the stability characteristics of a body with six rectangular fins of very low aspect ratio. The fins, which had exposed aspect ratios of approximately o.o4 and 0.02 per fin, were mounted on bodies of fineness ratios of 12 and 18, respectively. Each body had a nose with a fineness ratio of 3.5 and a cylindrical afterbody. The body and the fin chord of the model having a fineness ratio of 12 were extended the length of 6 body diameters to produce the model with a fineness ratio of 18. The missiles were disturbed in flight by pulse rockets in order to obtain the stability data. The tests were performed over a Mach number range of 1.4 to 3.2 and a Reynolds number range of 2 x 10(exp 6) to 21 x l0(exp 6). The results of these tests indicate that these configurations with the long rectangular fins of very low aspect ratio showed little induced roll" with the missile of highest fineness ratio and longest fin chord exhibiting the least amount. Extending the body and fin chord of the shorter missile six body diameters and thereby increasing the fin area approximately 115 percent increased the lift-curve slope based on body cross-sectional area approximately 40 to 55 percent, increased the dynamic stability by a substantial amount, and increased the drag from 14 to 33 percent throughout the comparable Mach number range. The center-of-pressure location of both missiles remained constant over the Mach number range.
Brown, Alexander M; Bejder, Lars; Parra, Guido J; Cagnazzi, Daniele; Hunt, Tim; Smith, Jennifer L; Allen, Simon J
2016-01-01
Determining the sex of free-ranging cetaceans can be challenging. Sexual dimorphism among external features may allow inferences on sex, but such patterns may be difficult to detect and are often confounded by age and geographic variation. Dorsal fin images of 107 female and 54 male Australian humpback dolphins, Sousa sahulensis, from Western Australia (WA) and Queensland (QLD) were used to investigate sex, age and geographic differences in colouration, height/length quotient and number of notches. Adult males exhibited more dorsal fin notches (p<0.001) and a significantly greater loss of pigmentation on the upper half of their dorsal fins (p<0.001) than did adult females. These differences likely reflect that males experience a higher frequency and/or intensity of intraspecific aggression than females. In QLD, heavily spotted dorsal fins were more frequent among females than males (p<0.001). Logistic regression analyses revealed that dorsal fin spotting and loss of pigmentation on the upper half of the dorsal fin provided the best model parameters for predicting the sex of sampled adults, with 97% accuracy. This technique offers a rapid, non-invasive method for predicting sex in Australian humpback dolphins, which could potentially be applied to populations throughout their range. In contrast to adults, presumed immature animals showed little or no loss of pigmentation or spotting; however, the rate of development of these features remains unknown. There were pronounced differences between QLD and WA in the intensity of spotting on dorsal fins and the extent of pigmentation loss around the posterior insertion and trailing edge of the dorsal fin. While based on a limited sample size, these geographic differences may have conservation implications in terms of population subdivision and should be investigated further. © 2016 Elsevier Ltd. All rights reserved.
Displaced humeral lateral condyle fractures in children: should we bury the pins?
Das De, Soumen; Bae, Donald S; Waters, Peter M
2012-09-01
The purpose of this investigation was to determine if leaving Kirschner wires exposed is more cost-effective than burying them subcutaneously after open reduction and internal fixation (ORIF) of humeral lateral condyle fractures. A retrospective cohort study of all lateral condyle fractures treated over a 10-year period at a single institution was performed. Data on surgical technique, fracture healing, and complications were analyzed, as well as treatment costs. A decision analysis model was then constructed to compare the strategies of leaving the pins exposed versus buried. Finally, sensitivity analyses were performed, assessing cost-effectiveness when infection rates and costs of treating deep infections were varied. A total of 235 children with displaced fractures were treated with ORIF using Kirschner wires. Pins were left exposed in 41 cases (17.4%) and buried in 194 cases (82.6%); the age, sex, injury mechanisms, and fracture patterns were similar in both the groups. The median time to removal of implants was shorter with exposed versus buried pins (4 vs. 6 wk, P<0.001), although there was no difference in fracture union or loss of reduction rates. The rate of superficial infection was higher with exposed pins (9.8% vs. 3.1%), but this was not statistically significant (P=0.076). There were no deep infections with exposed pins, whereas the rate of deep infection was 0.5% with buried pins (P=1.00). Buried pins were associated with additional complications, including symptomatic implants (7.2%); pins protruding through the skin (16%); internal pin migration necessitating additional surgery (1%); and skin necrosis (1%). The decision analysis revealed that leaving pins exposed resulted in an average cost savings of $3442 per patient. This strategy remained cost-effective even when infection rates with exposed pins approached 40%. Leaving the pins exposed after ORIF of lateral condyle fractures is safe and more cost-effective than burying the pins subcutaneously. Retrospective cohort study (level III).
Rodríguez, Alexis; Villegas, Elba; Montoya-Rosales, Alejandra; Rivas-Santiago, Bruno; Corzo, Gerardo
2014-01-01
The contention and treatment of Mycobacterium tuberculosis and other bacteria that cause infectious diseases require the use of new type of antibiotics. Pandinin 2 (Pin2) is a scorpion venom antimicrobial peptide highly hemolytic that has a central proline residue. This residue forms a structural “kink” linked to its pore-forming activity towards human erythrocytes. In this work, the residue Pro14 of Pin2 was both substituted and flanked using glycine residues (P14G and P14GPG) based on the low hemolytic activities of antimicrobial peptides with structural motifs Gly and GlyProGly such as magainin 2 and ponericin G1, respectively. The two Pin2 variants showed antimicrobial activity against E. coli, S. aureus, and M. tuberculosis. However, Pin2 [GPG] was less hemolytic (30%) than that of Pin2 [G] variant. In addition, based on the primary structure of Pin2 [G] and Pin2 [GPG], two short peptide variants were designed and chemically synthesized keeping attention to their physicochemical properties such as hydrophobicity and propensity to adopt alpha-helical conformations. The aim to design these two short antimicrobial peptides was to avoid the drawback cost associated to the synthesis of peptides with large sequences. The short Pin2 variants named Pin2 [14] and Pin2 [17] showed antibiotic activity against E. coli and M. tuberculosis. Besides, Pin2 [14] presented only 25% of hemolysis toward human erythrocytes at concentrations as high as 100 µM, while the peptide Pin2 [17] did not show any hemolytic effect at the same concentration. Furthermore, these short antimicrobial peptides had better activity at molar concentrations against multidrug resistance M. tuberculosis than that of the conventional antibiotics ethambutol, isoniazid and rifampicin. Therefore, Pin2 [14] and Pin2 [17] have the potential to be used as an alternative antibiotics and anti-tuberculosis agents with reduced hemolytic effects. PMID:25019413
Lim, Tae-Gyu; Lee, Sung-Young; Duan, Zhaoheng; Lee, Mee-Hyun; Chen, Hanyong; Liu, Fangfang; Liu, Kangdong; Jung, Sung Keun; Kim, Dong Joon; Bode, Ann M; Lee, Ki Won; Dong, Zigang
2017-05-01
Intake of soy isoflavones is inversely associated with the risk of esophageal cancer. Numerous experimental results have supported the anticancer activity of soy isoflavones. This study aimed to determine the anti-esophageal cancer activity of 6,7,4'-trihydroxyisoflavone (6,7,4'-THIF), a major metabolite of daidzein, which is readily metabolized in the human body. Notably, 6,7,4'-THIF inhibited proliferation and increased apoptosis of esophageal cancer cells. On the basis of a virtual screening analysis, Pin1 was identified as a target protein of 6,7,4'-THIF. Pull-down assay results using 6,7,4'-THIF Sepharose 4B beads showed a direct interaction between 6,7,4'-THIF and the Pin1 protein. Pin1 is a critical therapeutic and preventive target in esophageal cancer because of its positive regulation of β-catenin and cyclin D1. The 6,7,4'-THIF compound simultaneously reduced Pin1 isomerase activity and the downstream activation targets of Pin1. The specific inhibitory activity of 6,7,4'-THIF was analyzed using Neu/Pin1 wild-type (WT) and Neu/Pin1 knockout (KO) MEFs. 6,7,4'-THIF effected Neu/Pin1 WT MEFs, but not Neu/Pin1 KO MEFs. Furthermore, the results of a xenograft assay using Neu/Pin1 WT and KO MEFs were similar to those obtained from the in vitro assay. Overall, we found that 6,7,4'-THIF specifically reduced Pin1 activity in esophageal cancer models. Importantly, 6,7,4'-THIF directly bound to Pin1 but not FKBP or cyclophilin A, the same family of proteins. Because Pin1 acts like an oncogene by modulating various carcinogenesis-related proteins, this study might at least partially explain the underlying mechanism(s) of the anti-esophageal cancer effects of soy isoflavones. Cancer Prev Res; 10(5); 308-18. ©2017 AACR . ©2017 American Association for Cancer Research.
Van Wettere, Arnaud J; Redig, Patrick T; Wallace, Larry J; Bourgeault, Craig A; Bechtold, Joan E
2009-12-01
Use of external skeletal fixator-intramedullary pin (ESF-IM) tie-in fixators is an adjustable and effective method of fracture fixation in birds. The objective of this study was to determine the contribution of each of the following parameters to the compressive and torsional rigidity of an ESF-IM pin tie-in applied to avian bones with an osteotomy gap: (1) varying the fixation pin position in the proximal bone segment and (2) increasing the number of fixation pins in one or both bone segments. ESF-IM pin tie-in constructs were applied to humeri harvested from red-tailed hawks (Buteo jamaicensis) (n=24) that had been euthanatized for clinical reasons. Constructs with a variation in the placement of the proximal fixation pin and with 2, 3, or 4 fixation pins applied to avian bone with an osteotomy gap were loaded to a defined displacement in torque and axial compression. Response variables were determined from resulting load-displacement curves (construct stiffness, load at 1-mm displacement). Increasing the number of fixation pins from 1 to 2 per bone segment significantly increased the stiffness in torque (110%) and compression (60%), and the safe load in torque (107%) and compression (50%). Adding a fixation pin to the distal bone segment to form a 3-pin fixator significantly increased the stiffness (27%) and safe load (20%) in torque but not in axial compression. In the configuration with 2 fixation pins, placing the proximal pin distally in the proximal bone segment significantly increased the stiffness in torque (28%), and the safe load in torque (23%) and in axial compression (32%). Results quantified the relative importance of specific parameters affecting the rigidity of ESF-IM pin tie-in constructs as applied to unstable bone fracture models in birds.
Magnetoresistance measurement of permalloy thin film rings with triangular fins
NASA Astrophysics Data System (ADS)
Lai, Mei-Feng; Hsu, Chia-Jung; Liao, Chun-Neng; Chen, Ying-Jiun; Wei, Zung-Hang
2010-01-01
Magnetization reversals in permalloy rings controlled by nucleation sites using triangular fins at the same side and diagonal with respect to the field direction are demonstrated by magnetoresistance measurement and micromagnetic simulation. In the ring with triangular fins at the same side, there exists two-step reversal from onion to flux-closure state (or vortex state) and then from flux-closure (or vortex state) to reverse onion state; in the ring with diagonal triangular fins, one-step reversal occurs directly from onion to reverse onion state. The reversal processes are repeatable and controllable in contrast to an ideal ring without triangular fins where one-step and two-step reversals occur randomly in sweep-up and sweep-down processes.
Development and Application of Collaborative Optimization Software for Plate - fin Heat Exchanger
NASA Astrophysics Data System (ADS)
Chunzhen, Qiao; Ze, Zhang; Jiangfeng, Guo; Jian, Zhang
2017-12-01
This paper introduces the design ideas of the calculation software and application examples for plate - fin heat exchangers. Because of the large calculation quantity in the process of designing and optimizing heat exchangers, we used Visual Basic 6.0 as a software development carrier to design a basic calculation software to reduce the calculation quantity. Its design condition is plate - fin heat exchanger which was designed according to the boiler tail flue gas. The basis of the software is the traditional design method of the plate-fin heat exchanger. Using the software for design and calculation of plate-fin heat exchangers, discovery will effectively reduce the amount of computation, and similar to traditional methods, have a high value.
The X-38 V-201 Fin Fold Actuation Mechanism
NASA Technical Reports Server (NTRS)
Lupo, Christian; Robertson, Brandan; Gafka, George
2004-01-01
The X-38 Vehicle 201 (V-201) is a space flight prototype lifting body vehicle that was designed to launch to orbit in the Space Shuttle orbiter payload bay. Although the project was cancelled in May 2003, many of the systems were nearly complete. This paper will describe the fin folding actuation mechanism flight subsystems and development units as well as lessons learned in the design, assembly, development testing, and qualification testing. The two vertical tail fins must be stowed (folded inboard) to allow the orbiter payload bay doors to close. The fin folding actuation mechanism is a remotely or extravehicular activity (EVA) actuated single fault tolerant system consisting of seven subsystems capable of repeatedly deploying or stowing the fins.
Aerodynamic characteristics of cruciform missiles at high angles of attack
NASA Technical Reports Server (NTRS)
Lesieutre, Daniel J.; Mendenhall, Michael R.; Nazario, Susana M.; Hemsch, Michael J.
1987-01-01
An aerodynamic prediction method for missile aerodynamic performance and preliminary design has been developed to utilize a newly available systematic fin data base and an improved equivalent angle of attack methodology. The method predicts total aerodynamic loads and individual fin forces and moments for body-tail (wing-body) and canard-body-tail configurations with cruciform fin arrangements. The data base and the prediction method are valid for angles of attack up to 45 deg, arbitrary roll angles, fin deflection angles between -40 deg and 40 deg, Mach numbers between 0.6 and 4.5, and fin aspect ratios between 0.25 and 4.0. The equivalent angle of attack concept is employed to include the effects of vorticity and geometric scaling.
Role of fin material and nanofluid in performance enhancement of automobile radiator
NASA Astrophysics Data System (ADS)
Jadar, Raju; Shashishekar, K. S.; Channa Keshava Naik, N.
2018-04-01
An effective cooling system can avoid engine and its components from overheating and helps in achieving optimum engine performance. This work deals with the fabrication and performance evaluation of an automobile radiator with i) Aluminum fins and ii) Al-MWCNT fins using 0.1 w/v% f-MWCNT nanofluid. F-MWCNT nanoparticles in the base fluid improves the rate of heat transfer in an automobile radiator integrated with Al-MWCNT fins. The enhancement of heat transfer mainly depends on the quantity of F-MWCNT nanoparticles added to the host fluid. During the study it was found that at a low weight by volume concentration of nanofluid the heat transfer enhancement of 8% was achieved using Al-MWCNT fins compared to base fluid.
Hydrodynamical analysis of the effect of fish fins morphology
NASA Astrophysics Data System (ADS)
Azwadi Che Sidik, Nor; Yen, Tey Wah
2013-12-01
The previous works on the biomechanics of fishes focuses on the locomotion effect of the fish bodies. However, there is quite a insufficiency in unveiling the respective function of fins when the fishes pose statics and exposed to fluid flow. Accordingly, this paper's focus is to investigate the hydrodynamic effect of the fins configuration to the fluid flow of shark-shaped-inspired structure. The drag and lift coefficient is computed for different cases of fish fins addition and configuration. The k-epsilon turbulence model is deployed using finite volume method with the aid of commercial software ANSYS CFX. The finding will demystify some of the functions of the fish's fins in term of their contribution to the hydrodynamic flow around the fishes.
Haga, Ken; Sakai, Tatsuya
2013-01-01
In a recent study, we demonstrated that although the auxin efflux carrier PIN-FORMED (PIN) proteins, such as PIN3 and PIN7, are required for the pulse-induced first positive phototropism in etiolated Arabidopsis hypocotyls, they are not necessary for the continuous-light-induced second positive phototropism when the seedlings are grown on the surface of agar medium, which causes the hypocotyls to separate from the agar surface. Previous reports have shown that hypocotyl phototropism is slightly impaired in pin3 single mutants when they are grown along the surface of agar medium, where the hypocotyls always contact the agar, producing some friction. To clarify the possible involvement of PIN3 and PIN7 in continuous-light-induced phototropism, we investigated hypocotyl phototropism in the pin3 pin7 double mutant grown along the surface of agar medium. Intriguingly, the phototropic curvature was slightly impaired in the double mutant when the phototropic stimulus was presented on the adaxial side of the hook, but was not impaired when the phototropic stimulus was presented on the abaxial side of the hook. These results indicate that PIN proteins are required for continuous-light-induced second positive phototropism, depending on the direction of the light stimulus, when the seedlings are in contact with agar medium.
Haga, Ken; Sakai, Tatsuya
2013-01-01
In a recent study, we demonstrated that although the auxin efflux carrier PIN-FORMED (PIN) proteins, such as PIN3 and PIN7, are required for the pulse-induced first positive phototropism in etiolated Arabidopsis hypocotyls, they are not necessary for the continuous-light-induced second positive phototropism when the seedlings are grown on the surface of agar medium, which causes the hypocotyls to separate from the agar surface. Previous reports have shown that hypocotyl phototropism is slightly impaired in pin3 single mutants when they are grown along the surface of agar medium, where the hypocotyls always contact the agar, producing some friction. To clarify the possible involvement of PIN3 and PIN7 in continuous-light-induced phototropism, we investigated hypocotyl phototropism in the pin3 pin7 double mutant grown along the surface of agar medium. Intriguingly, the phototropic curvature was slightly impaired in the double mutant when the phototropic stimulus was presented on the adaxial side of the hook, but was not impaired when the phototropic stimulus was presented on the abaxial side of the hook. These results indicate that PIN proteins are required for continuous-light-induced second positive phototropism, depending on the direction of the light stimulus, when the seedlings are in contact with agar medium. PMID:23104115
Kim, Ji-Hyun; Jung, Ji Hoon; Kim, Sung-Hoon; Jeong, Soo-Jin
2014-02-01
The peptidyl-prolyl cis/trans isomerase Pin1 is overexpressed in a wide variety of cancer cells and thus considered as an important target molecule for cancer therapy. This study demonstrates that decursin, a bioactive compound from Angelica gigas, exert the anti-cancer effect against breast cancer cells via regulation of Pin1 and its related signaling molecules. We observed that decursin induced G1 arrest with decrease in cyclin D1 level in Pin1-expressing breast cancer cells MDA-MB-231, but not Pin1-non-expressing breast cancer cells MDA-MB-157. In addition, decursin significantly reduced protein expression and enzymatic activity of Pin1 in MDA-MB-231 cells. Further, we found that decursin treatment enhanced the p53 expression level and failed to down-regulate Pin1 in the cells transfected with p53 siRNA, indicating the importance of p53 in the decursin-mediated Pin1 inhibition in MDA-MB-231 cells. Decursin stimulated association between Pin1 to p53. Moreover, decursin facilitated p53 transcription in MDA-MB-231 cells. Overall, our current study suggests the potential of decursin as an attractive cancer therapeutic agent for breast cancer by targeting Pin1 protein. Copyright © 2013 John Wiley & Sons, Ltd.
Prolyl Isomerase Pin1 Regulates Neuronal Differentiation via β-Catenin
Nakamura, Kazuhiro; Kosugi, Isao; Lee, Daniel Y.; Hafner, Angela; Sinclair, David A.
2012-01-01
The Wnt/β-catenin pathway promotes proliferation of neural progenitor cells (NPCs) at early stages and induces neuronal differentiation from NPCs at late stages, but the molecular mechanisms that control this stage-specific response are unclear. Pin1 is a prolyl isomerase that regulates cell signaling uniquely by controlling protein conformation after phosphorylation, but its role in neuronal differentiation is not known. Here we found that whereas Pin1 depletion suppresses neuronal differentiation, Pin1 overexpression enhances it, without any effects on gliogenesis from NPCs in vitro. Consequently, Pin1-null mice have significantly fewer upper layer neurons in the motor cortex and severely impaired motor activity during the neonatal stage. A proteomic approach identified β-catenin as a major substrate for Pin1 in NPCs, in which Pin1 stabilizes β-catenin. As a result, Pin1 knockout leads to reduced β-catenin during differentiation but not proliferation of NPCs in developing brains. Importantly, defective neuronal differentiation in Pin1 knockout NPCs is fully rescued in vitro by overexpression of β-catenin but not a β-catenin mutant that fails to act as a Pin1 substrate. These results show that Pin1 is a novel regulator of NPC differentiation by acting on β-catenin and provides a new postphosphorylation signaling mechanism to regulate developmental stage-specific functioning of β-catenin signaling in neuronal differentiation. PMID:22645310
Pneumocranium secondary to halo vest pin penetration through an enlarged frontal sinus.
Cheong, Min Lee; Chan, Chris Yin Wei; Saw, Lim Beng; Kwan, Mun Keong
2009-07-01
We present a case report of a patient with pneumocranium secondary to halo vest pin penetration and a review of literature. The objectives of this study are to report a rare complication of halo vest pin insertion and to discuss methods of prevention of this complication. Halo vest orthosis is a commonly used and well-tolerated upper cervical spinal stabilizing device. Reports of complications related to pin penetration is rare and from our review, there has been no reports of pneumocranium occurring from insertion of pins following standard anatomical landmarks. A 57-year-old male sustained a type 1 traumatic spondylolisthesis of C2/C3 following a motor vehicle accident. During application of the halo vest, penetration of the left anterior pin through the abnormally enlarged frontal sinus occurred. The patient developed headache, vomiting and CSF rhinorrhoea over his left nostril. He was treated with intravenous Ceftriaxone for 1 week. This resulted in resolution of his symptoms as well as the pneumocranium. In conclusion, complications of halo vest pin penetration are rare and need immediate recognition. Despite the use of anatomical landmarks, pin penetration is still possible due to aberrant anatomy. All patients should have a skull X-ray with a radio-opaque marker done prior to placement of the halo vest pins and halo vest pins have to be inserted by experienced personnel to enable early detection of pin penetration.
Finite Element Analysis of Laser Engineered Net Shape (LENS™) Tungsten Clad Squeeze Pins
NASA Astrophysics Data System (ADS)
Sakhuja, Amit; Brevick, Jerald R.
2004-06-01
In the aluminum high-pressure die-casting and indirect squeeze casting processes, local "squeeze" pins are often used to minimize internal solidification shrinkage in heavy casting sections. Squeeze pins frequently fail in service due to molten aluminum adhering to the H13 tool steel pins ("soldering"). A wide variety of coating materials and methods have been developed to minimize soldering on H13. However, these coatings are typically very thin, and experience has shown their performance on squeeze pins is highly variable. The LENS™ process was employed in this research to deposit a relatively thick tungsten cladding on squeeze pins. An advantage of this process was that the process parameters could be precisely controlled in order to produce a satisfactory cladding. Two fixtures were designed and constructed to enable the end and outer diameter (OD) of the squeeze pins to be clad. Analyses were performed on the clad pins to evaluate the microstructure and chemical composition of the tungsten cladding and the cladding-H13 substrate interface. A thermo-mechanical finite element analysis (FEA) was performed to assess the stress distribution as a function of cladding thickness on the pins during a typical casting thermal cycle. FEA results were validated via a physical test, where the clad squeeze pins were immersed into molten aluminum. Pins subjected to the test were evaluated for thermally induced cracking and resistance to soldering of the tungsten cladding.
Simon, Sibu; Skůpa, Petr; Viaene, Tom; Zwiewka, Marta; Tejos, Ricardo; Klíma, Petr; Čarná, Mária; Rolčík, Jakub; De Rycke, Riet; Moreno, Ignacio; Dobrev, Petre I; Orellana, Ariel; Zažímalová, Eva; Friml, Jiří
2016-07-01
Plant development mediated by the phytohormone auxin depends on tightly controlled cellular auxin levels at its target tissue that are largely established by intercellular and intracellular auxin transport mediated by PIN auxin transporters. Among the eight members of the Arabidopsis PIN family, PIN6 is the least characterized candidate. In this study we generated functional, fluorescent protein-tagged PIN6 proteins and performed comprehensive analysis of their subcellular localization and also performed a detailed functional characterization of PIN6 and its developmental roles. The localization study of PIN6 revealed a dual localization at the plasma membrane (PM) and endoplasmic reticulum (ER). Transport and metabolic profiling assays in cultured cells and Arabidopsis strongly suggest that PIN6 mediates both auxin transport across the PM and intracellular auxin homeostasis, including the regulation of free auxin and auxin conjugates levels. As evidenced by the loss- and gain-of-function analysis, the complex function of PIN6 in auxin transport and homeostasis is required for auxin distribution during lateral and adventitious root organogenesis and for progression of these developmental processes. These results illustrate a unique position of PIN6 within the family of PIN auxin transporters and further add complexity to the developmentally crucial process of auxin transport. © 2016 The Authors. New Phytologist © 2016 New Phytologist Trust.
Anvil for Flaring PCB Guide Pins
NASA Technical Reports Server (NTRS)
Winn, E.; Turner, R.
1985-01-01
Spring-loaded anvil results in fewer fractured pins. New anvil for flaring guide pins in printed-circuit boards absorbs approximately 80 percent of press force. As result fewer pins damaged, and work output of flaring press greatly increased.
Proper PIN1 Distribution Is Needed for Root Negative Phototropism in Arabidopsis
Zhang, Kun-Xiao; Xu, Heng-Hao; Gong, Wen; Jin, Yan; Shi, Ya-Ya; Yuan, Ting-Ting; Li, Juan; Lu, Ying-Tang
2014-01-01
Plants can be adapted to the changing environments through tropic responses, such as light and gravity. One of them is root negative phototropism, which is needed for root growth and nutrient absorption. Here, we show that the auxin efflux carrier PIN-FORMED (PIN) 1 is involved in asymmetric auxin distribution and root negative phototropism. In darkness, PIN1 is internalized and localized to intracellular compartments; upon blue light illumination, PIN1 relocalize to basal plasma membrane in root stele cells. The shift of PIN1 localization induced by blue light is involved in asymmetric auxin distribution and root negative phototropic response. Both blue-light-induced PIN1 redistribution and root negative phototropism is mediated by a BFA-sensitive trafficking pathway and the activity of PID/PP2A. Our results demonstrate that blue-light-induced PIN1 redistribution participate in asymmetric auxin distribution and root negative phototropism. PMID:24465665
Proper PIN1 distribution is needed for root negative phototropism in Arabidopsis.
Zhang, Kun-Xiao; Xu, Heng-Hao; Gong, Wen; Jin, Yan; Shi, Ya-Ya; Yuan, Ting-Ting; Li, Juan; Lu, Ying-Tang
2014-01-01
Plants can be adapted to the changing environments through tropic responses, such as light and gravity. One of them is root negative phototropism, which is needed for root growth and nutrient absorption. Here, we show that the auxin efflux carrier PIN-FORMED (PIN) 1 is involved in asymmetric auxin distribution and root negative phototropism. In darkness, PIN1 is internalized and localized to intracellular compartments; upon blue light illumination, PIN1 relocalize to basal plasma membrane in root stele cells. The shift of PIN1 localization induced by blue light is involved in asymmetric auxin distribution and root negative phototropic response. Both blue-light-induced PIN1 redistribution and root negative phototropism is mediated by a BFA-sensitive trafficking pathway and the activity of PID/PP2A. Our results demonstrate that blue-light-induced PIN1 redistribution participate in asymmetric auxin distribution and root negative phototropism.
NASA Technical Reports Server (NTRS)
Burgess, Kevin (Inventor); Yakos, David (Inventor); Walthall, Bryan (Inventor)
2011-01-01
A stemless ball valve comprising two flanges and a ball with a channel, two axis pins and two travel pins. One end of each axis and travel pin is fixedly attached to the ball, and the other end of each axis pin is lodged into a notch in the first or second flange such that the axis pin is allowed to rotate in the notch. The guide sleeve comprises two channels, and one end of each travel pin is situated within one of the two channels in the guide sleeve. An outer magnetic cartridge causes the inner magnetic cartridge and guide sleeve to rotate, and when the guide sleeve rotates, the travel pins move up and down within the channels in the guide sleeve. The movement of the travel pins within the channels in the guide sleeve causes the ball to rotate, thereby opening and closing the ball valve.
NASA Technical Reports Server (NTRS)
Lu, F. K.; Settles, G. S.; Bogdonoff, S. M.
1983-01-01
The interaction between a turbulent boundary layer and a shock wave generated by a sharp fin with leading edge sweepback was investigated. The incoming flow was at Mach 2.96 and at a unit Reynolds number of 63 x 10 to the 6th power 0.1 m. The approximate incoming boundary layer thickness was either 4 mm or 17 mm. The fins used were at 5 deg, 9 deg and 15 deg incidence and had leading edge sweepback from 0 deg to 65 deg. The tests consisted of surface kerosene lampblack streak visualization, surface pressure measurements, shock wave shape determination by shadowgraphs, and localized vapor screen visualization. The upstream influence lengths of the fin interactions were correlated using viscous and inviscid flow parameters. The parameters affecting the surface features close to the fin and way from the fin were also identified. Essentially, the surface features in the farfield were found to be conical.
Male swordtails court with an audience in mind.
Fisher, Heidi S; Rosenthal, Gil G
2007-02-22
Females are usually considered to be the target of male courtship behaviour. In nature, however, social interactions rarely occur without other observers; thus, it is conceivable that some male courtship behaviours are directed not towards females, but rather towards male rivals. The northern swordtail, Xiphophorus birchmanni, is a freshwater fish found in high densities in natural streams. Males court by swimming close to and in parallel with the female, raising their large sail-like dorsal fin, and quivering briefly. Here, we show that females prefer males that display small dorsal fins to those with large ones, and that males are less aggressive to other males with large dorsal fins. Male swordtails also raise their dorsal fins more frequently when courting in the presence of other males. These results suggest that, despite female avoidance of large dorsal fins, males that raise their fin during courtship benefit by intimidating potential competitors; the intended receivers of this signal are thus males, not females. Intrasexual selection can therefore offset the forces of intersexual selection, even in a courtship display.
The fin-to-limb transition as the re-organization of a Turing pattern
Onimaru, Koh; Marcon, Luciano; Musy, Marco; Tanaka, Mikiko; Sharpe, James
2016-01-01
A Turing mechanism implemented by BMP, SOX9 and WNT has been proposed to control mouse digit patterning. However, its generality and contribution to the morphological diversity of fins and limbs has not been explored. Here we provide evidence that the skeletal patterning of the catshark Scyliorhinus canicula pectoral fin is likely driven by a deeply conserved Bmp–Sox9–Wnt Turing network. In catshark fins, the distal nodular elements arise from a periodic spot pattern of Sox9 expression, in contrast to the stripe pattern in mouse digit patterning. However, our computer model shows that the Bmp–Sox9–Wnt network with altered spatial modulation can explain the Sox9 expression in catshark fins. Finally, experimental perturbation of Bmp or Wnt signalling in catshark embryos produces skeletal alterations which match in silico predictions. Together, our results suggest that the broad morphological diversity of the distal fin and limb elements arose from the spatial re-organization of a deeply conserved Turing mechanism. PMID:27211489
García-Melo, J E; Albornoz-Garzón, J G; García-Melo, L J; Villa-Navarro, F A; Maldonado-Ocampo, J A
2018-04-16
Hemibrycon iqueima sp. nov., is described from small streams in the Magdalena drainage at the foothills of the western slope of the Eastern Cordillera of the Colombian Andes, Suarez municipality, Tolima Department, Colombia. The new species is distinguished from its congeners in the Magdalena-Cauca River basin by a combination of characters related to snout-anal-fin origin length, head length, dorsal-pectoral fin distance, dorsal-fin-hypural distance, postorbital distance, orbital diameter, snout length, number of total vertebrae, pre-dorsal scales, scale rows between anal-fin origin and lateral line, number of branched rays of the anal fin, maxillary teeth number and number and arrangement of hooks on the branched rays of the pectoral and dorsal fins. In addition, the validity of this species is supported by previous molecular analyses that included specimens of the new species that had been erroneously identified. Phylogenetic relationships between the new species and congeners from Pacific coast basins are discussed. This article is protected by copyright. All rights reserved.
Bio-inspired flexible joints with passive feathering for robotic fish pectoral fins.
Behbahani, Sanaz Bazaz; Tan, Xiaobo
2016-05-04
In this paper a novel flexible joint is proposed for robotic fish pectoral fins, which enables a swimming behavior emulating the fin motions of many aquatic animals. In particular, the pectoral fin operates primarily in the rowing mode, while undergoing passive feathering during the recovery stroke to reduce hydrodynamic drag on the fin. The latter enables effective locomotion even with symmetric base actuation during power and recovery strokes. A dynamic model is developed to facilitate the understanding and design of the joint, where blade element theory is used to calculate the hydrodynamic forces on the pectoral fins, and the joint is modeled as a paired torsion spring and damper. Experimental results on a robotic fish prototype are presented to illustrate the effectiveness of the joint mechanism, validate the proposed model, and indicate the utility of the proposed model for the optimal design of joint depth and stiffness in achieving the trade-off between swimming speed and mechanical efficiency.
NASA Astrophysics Data System (ADS)
Ambarita, H.; Ronowikarto, A. D.; Siregar, R. E. T.; Setyawan, E. Y.
2018-03-01
To reduce heat loses in a flat plate solar collector, double glasses cover is employed. Several studies show that the heat loss from the glass cover is still very significant in comparison with other losses. Here, double glasses cover with attached fins is proposed. In the present work, the fluid flow and heat transfer characteristics of the enclosure between the double glass cover are investigated numerically. The objective is to examine the effect of the fin to the heat transfer rate of the cover. Two-dimensional governing equations are developed. The governing equations and the boundary conditions are solved using commercial Computational Fluid Dynamics code. The fluid flow and heat transfer characteristics are plotted, and numerical results are compared with empirical correlation. The results show that the presence of the fin strongly affects the fluid flow and heat transfer characteristics. The fin can reduce the heat transfer rate up to 22.42% in comparison with double glasses cover without fins.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Kraus, A.; Garner, P.; Hanan, N.
Thermal-hydraulic simulations have been performed using computational fluid dynamics (CFD) for the highly-enriched uranium (HEU) design of the IVG.1M reactor at the Institute of Atomic Energy (IAE) at the National Nuclear Center (NNC) in the Republic of Kazakhstan. Steady-state simulations were performed for both types of fuel assembly (FA), i.e. the FA in rows 1 & 2 and the FA in row 3, as well as for single pins in those FA (600 mm and 800 mm pins). Both single pin calculations and bundle sectors have been simulated for the most conservative operating conditions corresponding to the 10 MW outputmore » power, which corresponds to a pin unit cell Reynolds number of only about 7500. Simulations were performed using the commercial code STAR-CCM+ for the actual twisted pin geometry as well as a straight-pin approximation. Various Reynolds-Averaged Navier-Stokes (RANS) turbulence models gave different results, and so some validation runs with a higher-fidelity Large Eddy Simulation (LES) code were performed given the lack of experimental data. These singled out the Realizable Two-Layer k-ε as the most accurate turbulence model for estimating surface temperature. Single-pin results for the twisted case, based on the average flow rate per pin and peak pin power, were conservative for peak clad surface temperature compared to the bundle results. Also the straight-pin calculations were conservative as compared to the twisted pin simulations, as expected, but the single-pin straight case was not always conservative with regard to the straight-pin bundle. This was due to the straight-pin temperature distribution being strongly influenced by the pin orientation, particularly near the outer boundary. The straight-pin case also predicted the peak temperature to be in a different location than the twisted-pin case. This is a limitation of the straight-pin approach. The peak temperature pin was in a different location from the peak power pin in every case simulated, and occurred at an inner pin just before the enrichment change. The 600 mm case demonstrated a peak clad surface temperature of 370.4 K, while the 800 mm case had a temperature of 391.6 K. These temperatures are well below the necessary temperatures for boiling to occur at the rated pressure. Fuel temperatures are also well below the melting point. Future bundle work will include simulations of the proposed low-enriched uranium (LEU) design. Two transient scenarios were also investigated for the single-pin geometries. Both were “model” problems that were focused on pure thermal-hydraulic behavior, and as such were simple power changes that did not incorporate neutron kinetics modeling. The first scenario was a high-power, ramp increase, while the second scenario was a low-power, step increase. A cylindrical RELAP model was also constructed to investigate its accuracy as compared to the higher-fidelity CFD. Comparisons between the two codes showed good agreement for peak temperatures in the fuel and at the cladding surface for both cases. In the step transient, temperatures at four axial levels were also computed. These showed greater but reasonable discrepancy, with RELAP outputting higher temperatures. These results provide some evidence that RELAP can be used with confidence in modeling transients for IVG.« less
A double tuned rail damper—increased damping at the two first pinned-pinned frequencies
NASA Astrophysics Data System (ADS)
Maes, J.; Sol, H.
2003-10-01
Railway-induced vibrations are a growing matter of environmental concern. The rapid development of transportation, the increase of vehicle speeds and vehicle weights have resulted in higher vibration levels. In the meantime vibrations that were tolerated in the past are now considered to be a nuisance. Numerous solutions have been proposed to remedy these problems. The majority only acts on a specific part of the dynamic behaviour of the track. This paper presents a possible solution to reduce the noise generated by the 'pinned-pinned' frequencies. Pinned-pinned frequencies correspond with standing waves whose nodes are positioned exactly at the sleeper supports. The two first pinned-pinned frequencies are situated approximately at 950 and 2200 Hz (UIC60-rail and sleeper spacing of 0.60 m). To attenuate these vibrations, the Department of MEMC at the VUB has developed a dynamic vibration absorber called the Double Tuned Rail Damper (DTRD). The DTRD is mounted between two sleepers on the rail and is powered by the motion of the rail. The DTRD consists of two major parts: a steel plate which is connected to the rail with an interface of an elastic layer, and a rubber mass. The two first resonance frequencies of the steel plate coincide with the targeted pinned-pinned frequencies of the rail. The rubber mass acts as a motion controller and energy absorber. Measurements at a test track of the French railway company (SNCF) have shown considerable attenuation of the envisaged pinned-pinned frequencies. The attenuation rate surpasses 5 dB/m at certain frequency bands.
Tips Under the Skin: A Simple Modification of Extension Block Pinning for Mallet Fractures.
Shin, Seung-Han; Lee, Yong-Suk; Kang, Jin-Woo; Kang, Wonwoo; Chung, Yang-Guk
2018-03-01
Pins exposed out of the skin after surgery for mallet fractures keep patients from washing their hands. The authors buried the tips of all pins under the skin while performing extension block pinning for 14 patients with mallet fractures. The patients were allowed to wash their hands 4 to 5 days postoperatively, without any dressing or splinting. The pins were removed at a mean of 8 weeks postoperatively. Solid union was achieved in all 14 fractures. No pull-out or subsidence of the pin was observed. No patient developed infection or other pin-related complications. Mean extension lag at final follow-up was 4°. [Orthopedics. 2018; 41(2):e299-e302.]. Copyright 2018, SLACK Incorporated.
NASA Astrophysics Data System (ADS)
Pradhan, K. P.; Priyanka; Sahu, P. K.
2016-01-01
Symmetric Dual-k Spacer (SDS) Trigate Wavy FinFET is a novel hybrid device that combines three significant and advanced technologies i.e., ultra-thin-body (UTB), FinFET, and symmetric spacer engineering on a single silicon on insulator (SOI) platform. This innovative architecture promises to enhance the device performance as compared to conventional FinFET without increasing the chip area. For the first time, we have incorporated two different dielectric materials (SiO2, and HfO2) as gate oxide to analyze the effect on various performance metrics of SDS wavy FinFET. This work evaluates the response of double material gate oxide (DMGO) on parameters like mobility, on current (Ion), transconductance (gm), transconductance generation factor (TGF), total gate capacitance (Cgg), and cutoff frequency (fT) in SDS wavy FinFET. This work also reveals the presence of biasing point i.e., zero temperature coefficient (ZTC) bias point. The ZTC bias point is that point where the device parameters become independent of temperature. The impact of operating temperature (T) on above said various performances are also subjected to extensive analysis. This further validates the reliability of DMGO-SDS FinFET and its application opportunities involved in modeling analog/RF circuits for a broad range of temperature applications. From extensive 3-D device simulation, we have determined that the inclusion of DMGO in SDS wavy FinFET is superior in performance.
Inhibition of caudal fin regeneration in Corydoras aeneus by lithium chloride.
Zarnescu, Otilia; Stavri, Simona; Moldovan, Lucia
2013-03-01
In the present study we examined the effects of lithium chloride on the Corydoras aeneus caudal fin regeneration. After caudal fin amputation, the fish were exposed 3h daily to 35 mM lithium chloride for 9 days. The effects of lithium chloride treatment were evaluated by analyzing the caudal fin structure at 3, 6 and 9 days after amputation. Comparison of normal and LiCl treated fish clearly shows that regeneration of amputated caudal fins was inhibited or delayed after lithium treatment. By the third day after amputation (dpa) either no epidermal cap or blastema ever formed or the epidermal cap had an abnormal morphology in lithium treated fish. By the 3 and 6 dpa no lepidotrichial matrix deposition was observed in the lithium treated fish compared to control fish. Unlike the control fish that completely regenerate their caudal fins after 9 dpa and have fully mineralized lepidotrichia, lithium treated fish have small blastema. In some treated fish, small amounts of new lepidotrichial matrix were observed at this time, in some fin rays. Ultrastructural observations have shown differences between control and lithium treated fish. Thus, in the lithium treated fish we observed expanded intercellular spaces between epidermal cells and many apoptotic cells. Results of this study suggest the use of this model in elucidating the molecular mechanisms that are responsible for regeneration of complex structures such as fish fins. Copyright © 2013 Elsevier Ltd. All rights reserved.
Rocha-Olivares, Axayácatl; Morteo, Rodrigo; Weller, David W.
2017-01-01
Geographic variation in external morphology is thought to reflect an interplay between genotype and the environment. Morphological variation has been well-described for a number of cetacean species, including the bottlenose dolphin (Tursiops truncatus). In this study we analyzed dorsal fin morphometric variation in coastal bottlenose dolphins to search for geographic patterns at different spatial scales. A total of 533 dorsal fin images from 19 available photo-identification catalogs across the three Mexican oceanic regions (Pacific Ocean n = 6, Gulf of California n = 6 and, Gulf of Mexico n = 7) were used in the analysis. Eleven fin shape measurements were analyzed to evaluate fin polymorphism through multivariate tests. Principal Component Analysis on log-transformed standardized ratios explained 94% of the variance. Canonical Discriminant Function Analysis on factor scores showed separation among most study areas (p < 0.05) with exception of the Gulf of Mexico where a strong morphometric cline was found. Possible explanations for the observed differences are related to environmental, biological and evolutionary processes. Shape distinction between dorsal fins from the Pacific and those from the Gulf of California were consistent with previously reported differences in skull morphometrics and genetics. Although the functional advantages of dorsal fin shape remains to be assessed, it is not unlikely that over a wide range of environments, fin shape may represent a trade-off among thermoregulatory capacity, hydrodynamic performance and the swimming/hunting behavior of the species. PMID:28626607
3D modeling of dual-gate FinFET.
Mil'shtein, Samson; Devarakonda, Lalitha; Zanchi, Brian; Palma, John
2012-11-13
The tendency to have better control of the flow of electrons in a channel of field-effect transistors (FETs) did lead to the design of two gates in junction field-effect transistors, field plates in a variety of metal semiconductor field-effect transistors and high electron mobility transistors, and finally a gate wrapping around three sides of a narrow fin-shaped channel in a FinFET. With the enhanced control, performance trends of all FETs are still challenged by carrier mobility dependence on the strengths of the electrical field along the channel. However, in cases when the ratio of FinFET volume to its surface dramatically decreases, one should carefully consider the surface boundary conditions of the device. Moreover, the inherent non-planar nature of a FinFET demands 3D modeling for accurate analysis of the device performance. Using the Silvaco modeling tool with quantization effects, we modeled a physical FinFET described in the work of Hisamoto et al. (IEEE Tran. Elec. Devices 47:12, 2000) in 3D. We compared it with a 2D model of the same device. We demonstrated that 3D modeling produces more accurate results. As 3D modeling results came close to experimental measurements, we made the next step of the study by designing a dual-gate FinFET biased at Vg1 >Vg2. It is shown that the dual-gate FinFET carries higher transconductance than the single-gate device.