Sample records for cites application procedures

  1. 40 CFR 152.86 - The cite-all method.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... types of data that EPA would require to be submitted if the application sought the initial registration... PESTICIDE REGISTRATION AND CLASSIFICATION PROCEDURES Procedures To Ensure Protection of Data Submitters' Rights § 152.86 The cite-all method. An applicant may comply with this subpart by citing all data in...

  2. 50 CFR 23.32 - How do I apply for a U.S. CITES document?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 50 Wildlife and Fisheries 6 2010-10-01 2010-10-01 false How do I apply for a U.S. CITES document... FAUNA AND FLORA (CITES) Application Procedures, Criteria, and Conditions § 23.32 How do I apply for a U.S. CITES document? (a) To apply for a U.S. CITES document, you must complete a standard application...

  3. 50 CFR 23.42 - What are the requirements for a plant hybrid?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... FAUNA AND FLORA (CITES) Application Procedures, Criteria, and Conditions § 23.42 What are the... import of a plant hybrid of a CITES species must be accompanied by a valid CITES document that shows the... a hybrid that includes two or more CITES species or taxa in its lineage? (1) YES. Consider the...

  4. 50 CFR 23.39 - What are the requirements for an introduction-from-the-sea certificate?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... IN ENDANGERED SPECIES OF WILD FAUNA AND FLORA (CITES) Application Procedures, Criteria, and... nomenclature in the CITES Appendices or the references adopted by the CoP. Yes Yes 23.23 (6) Live wildlife or... marine environment that is not under the jurisdiction of any country without a CITES document when all of...

  5. 40 CFR 152.95 - Citation of all studies in the Agency's files pertinent to a specific data requirement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... PROCEDURES Procedures To Ensure Protection of Data Submitters' Rights § 152.95 Citation of all studies in the... requirement. The applicant who selects this cite-all option must submit to the Agency: (a) A general offer to... may be limited to apply only to data pertinent to the specific data requirement(s) for which the cite...

  6. 50 CFR 23.33 - How is the decision made to issue or deny a request for a U.S. CITES document?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 50 Wildlife and Fisheries 9 2014-10-01 2014-10-01 false How is the decision made to issue or deny... INTERNATIONAL TRADE IN ENDANGERED SPECIES OF WILD FAUNA AND FLORA (CITES) Application Procedures, Criteria, and Conditions § 23.33 How is the decision made to issue or deny a request for a U.S. CITES document? (a) Upon...

  7. 50 CFR 23.33 - How is the decision made to issue or deny a request for a U.S. CITES document?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 50 Wildlife and Fisheries 9 2013-10-01 2013-10-01 false How is the decision made to issue or deny... INTERNATIONAL TRADE IN ENDANGERED SPECIES OF WILD FAUNA AND FLORA (CITES) Application Procedures, Criteria, and Conditions § 23.33 How is the decision made to issue or deny a request for a U.S. CITES document? (a) Upon...

  8. 50 CFR 23.33 - How is the decision made to issue or deny a request for a U.S. CITES document?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 50 Wildlife and Fisheries 9 2012-10-01 2012-10-01 false How is the decision made to issue or deny... INTERNATIONAL TRADE IN ENDANGERED SPECIES OF WILD FAUNA AND FLORA (CITES) Application Procedures, Criteria, and Conditions § 23.33 How is the decision made to issue or deny a request for a U.S. CITES document? (a) Upon...

  9. 50 CFR 23.33 - How is the decision made to issue or deny a request for a U.S. CITES document?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 50 Wildlife and Fisheries 8 2011-10-01 2011-10-01 false How is the decision made to issue or deny... INTERNATIONAL TRADE IN ENDANGERED SPECIES OF WILD FAUNA AND FLORA (CITES) Application Procedures, Criteria, and Conditions § 23.33 How is the decision made to issue or deny a request for a U.S. CITES document? (a) Upon...

  10. 50 CFR 23.54 - How long is a U.S. or foreign CITES document valid?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... ENDANGERED SPECIES OF WILD FAUNA AND FLORA (CITES) Application Procedures, Criteria, and Conditions § 23.54... certificate of origin will be valid for no longer than 12 months from the issuance date. (3) A traveling..., except under limited circumstances for certain timber species as outlined in § 23.73. ...

  11. 50 CFR 23.54 - How long is a U.S. or foreign CITES document valid?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... ENDANGERED SPECIES OF WILD FAUNA AND FLORA (CITES) Application Procedures, Criteria, and Conditions § 23.54... certificate of origin will be valid for no longer than 12 months from the issuance date. (3) A traveling..., except under limited circumstances for certain timber species as outlined in § 23.73. ...

  12. 50 CFR 23.54 - How long is a U.S. or foreign CITES document valid?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... ENDANGERED SPECIES OF WILD FAUNA AND FLORA (CITES) Application Procedures, Criteria, and Conditions § 23.54... certificate of origin will be valid for no longer than 12 months from the issuance date. (3) A traveling..., except under limited circumstances for certain timber species as outlined in § 23.73. ...

  13. 50 CFR 23.54 - How long is a U.S. or foreign CITES document valid?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... ENDANGERED SPECIES OF WILD FAUNA AND FLORA (CITES) Application Procedures, Criteria, and Conditions § 23.54... certificate of origin will be valid for no longer than 12 months from the issuance date. (3) A traveling..., except under limited circumstances for certain timber species as outlined in § 23.73. ...

  14. Top-cited publications on point-of-care ultrasound: The evolution of research trends.

    PubMed

    Liao, Shao-Feng; Chen, Pai-Jung; Chaou, Chung-Hsien; Lee, Ching-Hsing

    2018-01-06

    Point-of-care ultrasound (POCUS) has been a rapidly growing and broadly used modality in recent decades. The purpose of this study was to determine how POCUS is incorporated into clinical medicine by analyzing trends of use in the published literature. POCUS-related publications were retrieved from the Web of Science (WoS) database. The search results were ranked according to the number of times an article was cited during three time frames and average annual number of citations. Of the top 100 most cited publications in the four rankings, information regarding the publication journal, publication year, first author's nationality, field of POCUS application, and number of times the article was cited was recorded for trend analysis. A total of 7860 POCUS-related publications were retrieved, and publications related to POCUS increased from 8 in 1990 to 754 in 2016. The top 148 cited publications from the four ranking groups were included in this study. Trauma was the leading application field in which POCUS was studied prior to 2001. After 2004, thorax, cardiovascular, and procedure-guidance were the leading fields in POCUS research. >79% (118/148) of the top-cited publications were conducted by authors in the United States, Italy, and France. The majority of publications were published in critical care medicine and emergency medicine journals. In recent years, publications relating to POCUS have increased. POCUS-related research has mainly been performed in thorax, cardiovascular, and procedure-guidance ultrasonography fields, replacing trauma as the major field in which POCUS was previously studied. Copyright © 2018 Elsevier Inc. All rights reserved.

  15. EPA Approved Regulations in the California SIP

    EPA Pesticide Factsheets

    EPA approved California statutes and regulations incorporated by reference in the applicable State Implementation Plan (SIP), as well as approved test procedures, methods and specifications that are cited in certain regulations listed.

  16. 42 CFR 493.3 - Applicability.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... AND CERTIFICATION LABORATORY REQUIREMENTS General Provisions § 493.3 Applicability. (a) Basic rule. Except as specified in paragraph (b) of this section, a laboratory will be cited as out of compliance... procedures performed by the laboratory; or (2) Is CLIA-exempt. (b) Exception. These rules do not apply to...

  17. 42 CFR 493.3 - Applicability.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... AND CERTIFICATION LABORATORY REQUIREMENTS General Provisions § 493.3 Applicability. (a) Basic rule. Except as specified in paragraph (b) of this section, a laboratory will be cited as out of compliance... procedures performed by the laboratory; or (2) Is CLIA-exempt. (b) Exception. These rules do not apply to...

  18. 50 CFR 13.11 - Application procedures.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Rescue Center Program 50 CFR 23 (1) (1) CITES Registration of Commercial Breeding Operations for Appendix..., POSSESSION, TRANSPORTATION, SALE, PURCHASE, BARTER, EXPORTATION, AND IMPORTATION OF WILDLIFE AND PLANTS... Conservation Act permits (50 CFR 15); injurious wildlife permits (50 CFR 16); captive-bred wildlife...

  19. 50 CFR 13.11 - Application procedures.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Rescue Center Program 50 CFR 23 (1) (1) CITES Registration of Commercial Breeding Operations for Appendix..., POSSESSION, TRANSPORTATION, SALE, PURCHASE, BARTER, EXPORTATION, AND IMPORTATION OF WILDLIFE AND PLANTS... Conservation Act permits (50 CFR 15); injurious wildlife permits (50 CFR 16); captive-bred wildlife...

  20. 50 CFR 13.11 - Application procedures.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Rescue Center Program 50 CFR 23 (1) (1) CITES Registration of Commercial Breeding Operations for Appendix..., POSSESSION, TRANSPORTATION, SALE, PURCHASE, BARTER, EXPORTATION, AND IMPORTATION OF WILDLIFE AND PLANTS... Conservation Act permits (50 CFR 15); injurious wildlife permits (50 CFR 16); captive-bred wildlife...

  1. 50 CFR 13.11 - Application procedures.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Rescue Center Program 50 CFR 23 (1) (1) CITES Registration of Commercial Breeding Operations for Appendix..., POSSESSION, TRANSPORTATION, SALE, PURCHASE, BARTER, EXPORTATION, AND IMPORTATION OF WILDLIFE AND PLANTS... Conservation Act permits (50 CFR 15); injurious wildlife permits (50 CFR 16); captive-bred wildlife...

  2. 15 CFR 904.200 - Scope and applicability.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... administrative decisions of NOAA involving alleged violations of the laws cited in § 904.1(c) and regulations... basis for claiming the right to a hearing but, instead, prescribes procedures for the conduct of hearings, the right to which is provided by other authority. ...

  3. 50 CFR 13.11 - Application procedures.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Rescue Center Program 50 CFR 23 No fee CITES Registration of Commercial Breeding Operations for Appendix—I Wildlife 50 CFR 23 100 —Renewal of Registration of Commercial Breeding Operations for Appendix-I..., POSSESSION, TRANSPORTATION, SALE, PURCHASE, BARTER, EXPORTATION, AND IMPORTATION OF WILDLIFE AND PLANTS...

  4. Environmental Impact Analysis Process. Final Environmental Impact Statement for Proposed Air Force Reserve Mission Change (C-130 to C-5A Aircraft) and Westover Metropolitan Development Corporation (Expansion of Civil Aviation Operations through 1995) at Westover Air Force Base, Massachusetts. Volume 1

    DTIC Science & Technology

    1987-04-01

    many of which would not be acceptable under current environmental regula- tions but which were in compliance with the standards in effect at tK2 ...waste management regulations and issued a Notice of Violation (NOV) citing specific deficiencies in hazardous waste management procedures. The focus of...materials are handled and disposed of in compliance with applicable federal, state, and local regulations. Specific deficiencies cited in the NOV included

  5. Fracture control procedures for aircraft structural integrity

    NASA Technical Reports Server (NTRS)

    Wood, H. A.

    1972-01-01

    The application of applied fracture mechanics in the design, analysis, and qualification of aircraft structural systems are reviewed. Recent service experiences are cited. Current trends in high-strength materials application are reviewed with particular emphasis on the manner in which fracture toughness and structural efficiency may affect the material selection process. General fracture control procedures are reviewed in depth with specific reference to the impact of inspectability, structural arrangement, and material on proposed analysis requirements for safe crack growth. The relative impact on allowable design stress is indicated by example. Design criteria, material, and analysis requirements for implementation of fracture control procedures are reviewed together with limitations in current available data techniques. A summary of items which require further study and attention is presented.

  6. Retrieval of radiology reports citing critical findings with disease-specific customization.

    PubMed

    Lacson, Ronilda; Sugarbaker, Nathanael; Prevedello, Luciano M; Ivan, Ip; Mar, Wendy; Andriole, Katherine P; Khorasani, Ramin

    2012-01-01

    Communication of critical results from diagnostic procedures between caregivers is a Joint Commission national patient safety goal. Evaluating critical result communication often requires manual analysis of voluminous data, especially when reviewing unstructured textual results of radiologic findings. Information retrieval (IR) tools can facilitate this process by enabling automated retrieval of radiology reports that cite critical imaging findings. However, IR tools that have been developed for one disease or imaging modality often need substantial reconfiguration before they can be utilized for another disease entity. THIS PAPER: 1) describes the process of customizing two Natural Language Processing (NLP) and Information Retrieval/Extraction applications - an open-source toolkit, A Nearly New Information Extraction system (ANNIE); and an application developed in-house, Information for Searching Content with an Ontology-Utilizing Toolkit (iSCOUT) - to illustrate the varying levels of customization required for different disease entities and; 2) evaluates each application's performance in identifying and retrieving radiology reports citing critical imaging findings for three distinct diseases, pulmonary nodule, pneumothorax, and pulmonary embolus. Both applications can be utilized for retrieval. iSCOUT and ANNIE had precision values between 0.90-0.98 and recall values between 0.79 and 0.94. ANNIE had consistently higher precision but required more customization. Understanding the customizations involved in utilizing NLP applications for various diseases will enable users to select the most suitable tool for specific tasks.

  7. 50 CFR 23.38 - What are the requirements for a certificate of origin?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... certificate of origin? 23.38 Section 23.38 Wildlife and Fisheries UNITED STATES FISH AND WILDLIFE SERVICE... ENDANGERED SPECIES OF WILD FAUNA AND FLORA (CITES) Application Procedures, Criteria, and Conditions § 23.38 What are the requirements for a certificate of origin? (a) Purpose. Article V(3) of the Treaty requires...

  8. 50 CFR 23.38 - What are the requirements for a certificate of origin?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... certificate of origin? 23.38 Section 23.38 Wildlife and Fisheries UNITED STATES FISH AND WILDLIFE SERVICE... ENDANGERED SPECIES OF WILD FAUNA AND FLORA (CITES) Application Procedures, Criteria, and Conditions § 23.38 What are the requirements for a certificate of origin? (a) Purpose. Article V(3) of the Treaty requires...

  9. 50 CFR 23.38 - What are the requirements for a certificate of origin?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... certificate of origin? 23.38 Section 23.38 Wildlife and Fisheries UNITED STATES FISH AND WILDLIFE SERVICE... ENDANGERED SPECIES OF WILD FAUNA AND FLORA (CITES) Application Procedures, Criteria, and Conditions § 23.38 What are the requirements for a certificate of origin? (a) Purpose. Article V(3) of the Treaty requires...

  10. 50 CFR 23.38 - What are the requirements for a certificate of origin?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... certificate of origin? 23.38 Section 23.38 Wildlife and Fisheries UNITED STATES FISH AND WILDLIFE SERVICE... ENDANGERED SPECIES OF WILD FAUNA AND FLORA (CITES) Application Procedures, Criteria, and Conditions § 23.38 What are the requirements for a certificate of origin? (a) Purpose. Article V(3) of the Treaty requires...

  11. 50 CFR 23.38 - What are the requirements for a certificate of origin?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... certificate of origin? 23.38 Section 23.38 Wildlife and Fisheries UNITED STATES FISH AND WILDLIFE SERVICE... ENDANGERED SPECIES OF WILD FAUNA AND FLORA (CITES) Application Procedures, Criteria, and Conditions § 23.38 What are the requirements for a certificate of origin? (a) Purpose. Article V(3) of the Treaty requires...

  12. 50 CFR 23.40 - What are the requirements for a certificate for artificially propagated plants?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... INTERNATIONAL TRADE IN ENDANGERED SPECIES OF WILD FAUNA AND FLORA (CITES) Application Procedures, Criteria, and... listed on the certificate, inventory sheet, or an approved species list. (4) You may export a specimen... exhibition. (iii) Is a hybrid of one or more Appendix-I species or taxa that is not annotated to include...

  13. 50 CFR 23.40 - What are the requirements for a certificate for artificially propagated plants?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... INTERNATIONAL TRADE IN ENDANGERED SPECIES OF WILD FAUNA AND FLORA (CITES) Application Procedures, Criteria, and... specifically approved for export and listed on the certificate, inventory sheet, or an approved species list... exhibition. (iii) Is a hybrid of one or more Appendix-I species or taxa that is not annotated to treat...

  14. 50 CFR 23.40 - What are the requirements for a certificate for artificially propagated plants?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... INTERNATIONAL TRADE IN ENDANGERED SPECIES OF WILD FAUNA AND FLORA (CITES) Application Procedures, Criteria, and... listed on the certificate, inventory sheet, or an approved species list. (4) You may export a specimen... exhibition. (iii) Is a hybrid of one or more Appendix-I species or taxa that is not annotated to include...

  15. 50 CFR 23.40 - What are the requirements for a certificate for artificially propagated plants?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... INTERNATIONAL TRADE IN ENDANGERED SPECIES OF WILD FAUNA AND FLORA (CITES) Application Procedures, Criteria, and... listed on the certificate, inventory sheet, or an approved species list. (4) You may export a specimen... exhibition. (iii) Is a hybrid of one or more Appendix-I species or taxa that is not annotated to include...

  16. 50 CFR 23.40 - What are the requirements for a certificate for artificially propagated plants?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... INTERNATIONAL TRADE IN ENDANGERED SPECIES OF WILD FAUNA AND FLORA (CITES) Application Procedures, Criteria, and... listed on the certificate, inventory sheet, or an approved species list. (4) You may export a specimen... exhibition. (iii) Is a hybrid of one or more Appendix-I species or taxa that is not annotated to include...

  17. Retrieval of Radiology Reports Citing Critical Findings with Disease-Specific Customization

    PubMed Central

    Lacson, Ronilda; Sugarbaker, Nathanael; Prevedello, Luciano M; Ivan, IP; Mar, Wendy; Andriole, Katherine P; Khorasani, Ramin

    2012-01-01

    Background: Communication of critical results from diagnostic procedures between caregivers is a Joint Commission national patient safety goal. Evaluating critical result communication often requires manual analysis of voluminous data, especially when reviewing unstructured textual results of radiologic findings. Information retrieval (IR) tools can facilitate this process by enabling automated retrieval of radiology reports that cite critical imaging findings. However, IR tools that have been developed for one disease or imaging modality often need substantial reconfiguration before they can be utilized for another disease entity. Purpose: This paper: 1) describes the process of customizing two Natural Language Processing (NLP) and Information Retrieval/Extraction applications – an open-source toolkit, A Nearly New Information Extraction system (ANNIE); and an application developed in-house, Information for Searching Content with an Ontology-Utilizing Toolkit (iSCOUT) – to illustrate the varying levels of customization required for different disease entities and; 2) evaluates each application’s performance in identifying and retrieving radiology reports citing critical imaging findings for three distinct diseases, pulmonary nodule, pneumothorax, and pulmonary embolus. Results: Both applications can be utilized for retrieval. iSCOUT and ANNIE had precision values between 0.90-0.98 and recall values between 0.79 and 0.94. ANNIE had consistently higher precision but required more customization. Conclusion: Understanding the customizations involved in utilizing NLP applications for various diseases will enable users to select the most suitable tool for specific tasks. PMID:22934127

  18. Formal Methods for Life-Critical Software

    NASA Technical Reports Server (NTRS)

    Butler, Ricky W.; Johnson, Sally C.

    1993-01-01

    The use of computer software in life-critical applications, such as for civil air transports, demands the use of rigorous formal mathematical verification procedures. This paper demonstrates how to apply formal methods to the development and verification of software by leading the reader step-by-step through requirements analysis, design, implementation, and verification of an electronic phone book application. The current maturity and limitations of formal methods tools and techniques are then discussed, and a number of examples of the successful use of formal methods by industry are cited.

  19. 40 CFR 152.86 - The cite-all method.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...' Rights § 152.86 The cite-all method. An applicant may comply with this subpart by citing all data in... 40 Protection of Environment 23 2010-07-01 2010-07-01 false The cite-all method. 152.86 Section... relies on the following data: (1) All data submitted with or specifically cited in the application; and...

  20. 46 CFR 385.8 - Arrangement.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...Ad assistance regulations will be cited in accordance with Federal Register standards. Thus, this paragraph, when referred to within divisions of the MarAd assistance regulations, should be cited as “§ 385... be cited as “46 CFR 385.8(b).” (c) Implementation. Instructions and procedures needed by MarAd to...

  1. MILSTAMP TACs: Military Standard Transportation and Movement Procedures Transportation Account Codes. Volume 2

    DTIC Science & Technology

    1987-02-15

    this chapter. NO - If shipment is not second des - tination transportation , obtain fund cite per yes response for question 2 above. 4. For Direct Support...return . . . . . . . . .0 . . . . . . . a. . .. A820 (8) LOGAIR/QUICKTRANS. Transportation Account Codes de - signed herein are applicable to the...oo~• na~- Transportation Tis Document Contains Tasotto Missing Page/s That Are Unavailable In The And Original Document Movement sdocument has boon

  2. Object oriented development of engineering software using CLIPS

    NASA Technical Reports Server (NTRS)

    Yoon, C. John

    1991-01-01

    Engineering applications involve numeric complexity and manipulations of a large amount of data. Traditionally, numeric computation has been the concern in developing an engineering software. As engineering application software became larger and more complex, management of resources such as data, rather than the numeric complexity, has become the major software design problem. Object oriented design and implementation methodologies can improve the reliability, flexibility, and maintainability of the resulting software; however, some tasks are better solved with the traditional procedural paradigm. The C Language Integrated Production System (CLIPS), with deffunction and defgeneric constructs, supports the procedural paradigm. The natural blending of object oriented and procedural paradigms has been cited as the reason for the popularity of the C++ language. The CLIPS Object Oriented Language's (COOL) object oriented features are more versatile than C++'s. A software design methodology based on object oriented and procedural approaches appropriate for engineering software, and to be implemented in CLIPS was outlined. A method for sensor placement for Space Station Freedom is being implemented in COOL as a sample problem.

  3. Multivariate Quality Control Procedures

    DTIC Science & Technology

    1988-10-01

    CLASSIFICATION OF THIS PAGE PREFACE The mathematical modeling work described in this report was authorized under Project No. IC162706A553, CB Defense and...the sum of the measurements. A CUSUM of the first principal component would detect changes in the overall thickness of the sheet. A linear trend could...develop- ment of a unique outlier rule for the specific application. 28 LITERATURE CITED 1. Mood, A.M., Graybill , F.A., and Boes, D.C., Introduction to

  4. 40 CFR 455.50 - Identification of test procedures.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... methods cited and described in Table IG at 40 CFR 136.3(a). Pesticide manufacturers may not use the analytical method cited in Table IB, Table IC, or Table ID of 40 CFR 136.3(a) to make these determinations (except where the method cited in those tables is identical to the method specified in Table IG at 40 CFR...

  5. 75 FR 34757 - Information Collection Sent to the Office of Management and Budget (OMB) for Approval; OMB...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-18

    ...-0137; Applications for Single Use Permits and Registration of Production Facilities (CITES) AGENCY...-0137. Title: Applications for Single Use Permits and Registration of Production Facilities (CITES), 50... import or export of CITES-listed species, the Management Authority and Scientific Authority must make...

  6. 32 CFR 806.3 - Public information.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Force records, whether the requester cites the FOIA or not, must comply with the principles of the FOIA... control the request as a FOIA and follow FOIA denial procedures for records withheld (cite the pertinent FOIA exemption and give the requester FOIA appeal rights). (b) HQ AFCIC/ITC will make the Air Force...

  7. 78 FR 29659 - Forfeiture Procedures Under the Endangered Species Act and the Lacey Act Amendments

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-21

    ... products imported in violation of CITES. APHIS initiates approximately 100 seizures each year for CITES... DEPARTMENT OF AGRICULTURE Animal and Plant Health Inspection Service 7 CFR Part 356 [Docket No... Amendments AGENCY: Animal and Plant Health Inspection Service, USDA. ACTION: Proposed rule. SUMMARY: The...

  8. 32 CFR 293.6 - Procedures.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... database, and initiates the record search. If a final response cannot be made to the FOIA requester within... FOIA and the Privacy Act. Not all requesters will be knowledgeable of the appropriate act to cite when requesting records or access to records. In some instances, either the FOIA or the Privacy Act may be cited...

  9. 32 CFR 293.6 - Procedures.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... database, and initiates the record search. If a final response cannot be made to the FOIA requester within... FOIA and the Privacy Act. Not all requesters will be knowledgeable of the appropriate act to cite when requesting records or access to records. In some instances, either the FOIA or the Privacy Act may be cited...

  10. 32 CFR 293.6 - Procedures.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... database, and initiates the record search. If a final response cannot be made to the FOIA requester within... FOIA and the Privacy Act. Not all requesters will be knowledgeable of the appropriate act to cite when requesting records or access to records. In some instances, either the FOIA or the Privacy Act may be cited...

  11. Continuously Variable Rating: a new, simple and logical procedure to evaluate original scientific publications

    PubMed Central

    Silva, Mauricio Rocha e

    2011-01-01

    OBJECTIVE: Impact Factors (IF) are widely used surrogates to evaluate single articles, in spite of known shortcomings imposed by cite distribution skewness. We quantify this asymmetry and propose a simple computer-based procedure for evaluating individual articles. METHOD: (a) Analysis of symmetry. Journals clustered around nine Impact Factor points were selected from the medical “Subject Categories” in Journal Citation Reports 2010. Citable items published in 2008 were retrieved and ranked by granted citations over the Jan/2008 - Jun/2011 period. Frequency distribution of cites, normalized cumulative cites and absolute cites/decile were determined for each journal cluster. (b) Positive Predictive Value. Three arbitrarily established evaluation classes were generated: LOW (1.3≤IF<2.6); MID: (2.6≤IF<3.9); HIGH: (IF≥3.9). Positive Predictive Value for journal clusters within each class range was estimated. (c) Continuously Variable Rating. An alternative evaluation procedure is proposed to allow the rating of individually published articles in comparison to all articles published in the same journal within the same year of publication. The general guiding lines for the construction of a totally dedicated software program are delineated. RESULTS AND CONCLUSIONS: Skewness followed the Pareto Distribution for (1

  12. Perspectives of EFL Doctoral Students on Challenges of Citations in Academic Writing

    ERIC Educational Resources Information Center

    Jomaa, Nayef Jomaa; Bidin, Siti Jamilah

    2017-01-01

    Purpose: Citation is vital in academic writing but particularly challenging for novice writers who use English as a second or foreign language. While much is known about citations types and functions, scarce knowledge is available about what makes citing a complicated procedure. Hence, this study explores the difficulties in citing and integrating…

  13. Macromolecule mass spectrometry: citation mining of user documents.

    PubMed

    Kostoff, Ronald N; Bedford, Clifford D; del Río, J Antonio; Cortes, Héctor D; Karypis, George

    2004-03-01

    Identifying research users, applications, and impact is important for research performers, managers, evaluators, and sponsors. Identification of the user audience and the research impact is complex and time consuming due to the many indirect pathways through which fundamental research can impact applications. This paper identified the literature pathways through which two highly-cited papers of 2002 Chemistry Nobel Laureates Fenn and Tanaka impacted research, technology development, and applications. Citation Mining, an integration of citation bibliometrics and text mining, was applied to the >1600 first generation Science Citation Index (SCI) citing papers to Fenn's 1989 Science paper on Electrospray Ionization for Mass Spectrometry, and to the >400 first generation SCI citing papers to Tanaka's 1988 Rapid Communications in Mass Spectrometry paper on Laser Ionization Time-of-Flight Mass Spectrometry. Bibliometrics was performed on the citing papers to profile the user characteristics. Text mining was performed on the citing papers to identify the technical areas impacted by the research, and the relationships among these technical areas.

  14. 15 CFR 904.100 - General.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE GENERAL REGULATIONS CIVIL PROCEDURES Civil Penalties § 904.100 General. This subpart sets forth the procedures governing NOAA administrative proceedings for the assessment of civil penalties under the statutes cited in § 904.1(c). ...

  15. 15 CFR 904.100 - General.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE GENERAL REGULATIONS CIVIL PROCEDURES Civil Penalties § 904.100 General. This subpart sets forth the procedures governing NOAA administrative proceedings for the assessment of civil penalties under the statutes cited in § 904.1(c). ...

  16. School Business. A Manual for School Officials. Revised Edition.

    ERIC Educational Resources Information Center

    Smith, Richard N.

    An outline is presented of business procedures related to the many facets of educational program operations. Statutes, regulations, practices, attorney general's opinions and reports, and court decisions relative to school business in Iowa are cited. While the report is a review of the procedures for the state of Iowa, a number of procedures are…

  17. 40 CFR 152.86 - The cite-all method.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 24 2014-07-01 2014-07-01 false The cite-all method. 152.86 Section 152.86 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS... Data Submitters' Rights § 152.86 The cite-all method. An applicant may comply with this subpart by...

  18. 75 FR 8102 - Proposed Information Collection; OMB Control Number 1018-0137; Applications for Single Use...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-23

    ... Registration of Production Facilities (CITES) AGENCY: Fish and Wildlife Service, Interior. ACTION: Notice... to the import or export of CITES-listed species, the Management Authority and Scientific Authority... and U.S. Scientific Authority for CITES. The Secretary delegated these authorities to the Fish and...

  19. 40 CFR 152.93 - Citation of a previously submitted valid study.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Data Submitters' Rights § 152.93 Citation of a previously submitted valid study. An applicant may demonstrate compliance for a data requirement by citing a valid study previously submitted to the Agency. The... the original data submitter, the applicant may cite the study only in accordance with paragraphs (b...

  20. 39 CFR 3001.4 - Method of citing rules.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 39 Postal Service 1 2010-07-01 2010-07-01 false Method of citing rules. 3001.4 Section 3001.4... Applicability § 3001.4 Method of citing rules. This part shall be referred to as the “rules of practice.” Each section, paragraph, or subparagraph shall include only the numbers and letters to the right of the decimal...

  1. Users guide for WoodCite, a product cost quotation tool for wood component manufacturers [computer program

    Treesearch

    Jeff Palmer; Adrienn Andersch; Jan Wiedenbeck; Urs. Buehlmann

    2014-01-01

    WoodCite is a Microsoft® Access-based application that allows wood component manufacturers to develop product price quotations for their current and potential customers. The application was developed by the U.S. Forest Service and Virginia Polytechnic Institute and State University, in cooperation with the Wood Components Manufacturers Association.

  2. Three Cheers for Language: A Closer Examination of a Widely Cited Study of Nonverbal Communication.

    ERIC Educational Resources Information Center

    Lapakko, David

    1997-01-01

    Focuses on applications of a widely cited empirical study in the communication field--A. Mehrabian and S. Ferris' 1967 study that inferred that communication is 7% verbal, 38% vocal, and 55% facial. Notes that these applications overlook important limitations which do not warrant formulation of a precise numerical formula. Discusses lessons…

  3. Administrative Plans. STIP II (Skill Training Improvement Programs Round II).

    ERIC Educational Resources Information Center

    Los Angeles Community Coll. District, CA.

    Personnel policies, job responsibilities, and accounting procedures are summarized for the Los Angeles Community College District's Skill Training Improvement Programs (STIP II). This report first cites references to the established personnel and affirmative action procedures governing the program and then presents an organizational chart for the…

  4. Beyond the operating room: a look at legal liability in body contouring procedures.

    PubMed

    Paik, Angie M; Mady, Leila J; Sood, Aditya; Lee, Edward S

    2014-01-01

    Malpractice claims affect the cost and quality of health care. In this study, the authors examine legal litigation following body contouring surgery and identify factors influencing malpractice litigation outcomes. The Westlaw legal database was searched for jury verdict and settlement reports related to body contouring procedures and medical malpractice. Cases included for analysis were examined for year of report, geographic location, patient demographics, procedure performed, alleged injury, causes of action, verdict, and indemnity payments. Of 113 cases, the most common injuries sustained were disfigurement (33.6%) and the necessitation of a revision procedure (33.6%). The most common cause of action cited was negligence (84.1%). Median plaintiff ages differed significantly (P = .003) between cases favoring the defendant (44.5 years) and those favoring the plaintiff (36 years). Of the alleged injuries, those cases citing an iatrogenic injury were 2.5 times more likely to result in either damages awarded or settlement (relative risk [RR], 2.5; 95% confidence interval [CI], 1.66-3.80). Cases that cited disfigurement were 87% more likely to result in damages awarded to the plaintiff (RR, 1.87; 95% CI, 1.08-3.26). Based on this study of body contouring litigation, younger plaintiff age and iatrogenic injury strongly favored plaintiffs in either awarded damages or a settlement. Disfigurement favored plaintiffs only in awarded damages. Our study emphasizes the need for adequate communication with the patient explaining realistic aesthetic results and risks of the procedure. In addition, iatrogenic organ injury must be handled expeditiously. Incorporating these recommendations into clinical practice may promote an improved physician-patient relationship while reducing litigatious health care costs.

  5. Input Files and Procedures for Analysis of SMA Hybrid Composite Beams in MSC.Nastran and ABAQUS

    NASA Technical Reports Server (NTRS)

    Turner, Travis L.; Patel, Hemant D.

    2005-01-01

    A thermoelastic constitutive model for shape memory alloys (SMAs) and SMA hybrid composites (SMAHCs) was recently implemented in the commercial codes MSC.Nastran and ABAQUS. The model is implemented and supported within the core of the commercial codes, so no user subroutines or external calculations are necessary. The model and resulting structural analysis has been previously demonstrated and experimentally verified for thermoelastic, vibration and acoustic, and structural shape control applications. The commercial implementations are described in related documents cited in the references, where various results are also shown that validate the commercial implementations relative to a research code. This paper is a companion to those documents in that it provides additional detail on the actual input files and solution procedures and serves as a repository for ASCII text versions of the input files necessary for duplication of the available results.

  6. Going, going, still there: using the WebCite service to permanently archive cited web pages.

    PubMed

    Eysenbach, Gunther; Trudel, Mathieu

    2005-12-30

    Scholars are increasingly citing electronic "web references" which are not preserved in libraries or full text archives. WebCite is a new standard for citing web references. To "webcite" a document involves archiving the cited Web page through www.webcitation.org and citing the WebCite permalink instead of (or in addition to) the unstable live Web page. This journal has amended its "instructions for authors" accordingly, asking authors to archive cited Web pages before submitting a manuscript. Almost 200 other journals are already using the system. We discuss the rationale for WebCite, its technology, and how scholars, editors, and publishers can benefit from the service. Citing scholars initiate an archiving process of all cited Web references, ideally before they submit a manuscript. Authors of online documents and websites which are expected to be cited by others can ensure that their work is permanently available by creating an archived copy using WebCite and providing the citation information including the WebCite link on their Web document(s). Editors should ask their authors to cache all cited Web addresses (Uniform Resource Locators, or URLs) "prospectively" before submitting their manuscripts to their journal. Editors and publishers should also instruct their copyeditors to cache cited Web material if the author has not done so already. Finally, WebCite can process publisher submitted "citing articles" (submitted for example as eXtensible Markup Language [XML] documents) to automatically archive all cited Web pages shortly before or on publication. Finally, WebCite can act as a focussed crawler, caching retrospectively references of already published articles. Copyright issues are addressed by honouring respective Internet standards (robot exclusion files, no-cache and no-archive tags). Long-term preservation is ensured by agreements with libraries and digital preservation organizations. The resulting WebCite Index may also have applications for research assessment exercises, being able to measure the impact of Web services and published Web documents through access and Web citation metrics.

  7. MAJOR TRANSPORT MECHANISMS OF PYRETHROIDS IN RESIDENTIAL SETTINGS AND EFFECTS OF MITIGATION MEASURES

    PubMed Central

    Davidson, Paul C; Jones, Russell L; Harbourt, Christopher M; Hendley, Paul; Goodwin, Gregory E; Sliz, Bradley A

    2014-01-01

    The major pathways for transport of pyrethroids were determined in runoff studies conducted at a full-scale test facility in central California, USA. The 6 replicate house lots were typical of front lawns and house fronts of California residential developments and consisted of stucco walls, garage doors, driveways, and residential lawn irrigation sprinkler systems. Each of the 6 lots also included a rainfall simulator to generate artificial rainfall events. Different pyrethroids were applied to 5 surfaces—driveway, garage door and adjacent walls, lawn, lawn perimeter (grass near the house walls), and house walls above grass. The volume of runoff water from each house lot was measured, sampled, and analyzed to determine the amount of pyrethroid mass lost from each surface. Applications to 3 of the house lots were made using the application practices typically used prior to recent label changes, and applications were made to the other 3 house lots according to the revised application procedures. Results from the house lots using the historic application procedures showed that losses of the compounds applied to the driveway and garage door (including the adjacent walls) were 99.75% of total measured runoff losses. The greatest losses were associated with significant rainfall events rather than lawn irrigation events. However, runoff losses were 40 times less using the revised application procedures recently specified on pyrethroid labels. Environ Toxicol Chem 2014;33:52–60. © 2013 The Authors. Environmental Toxicology and Chemistry published by Wiley Periodicals, Inc. on behalf of SETAC. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution, and reproduction in any medium, provided the original work is properly cited. PMID:24105831

  8. 22 CFR 505.3 - Procedures for requests.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Foreign Relations BROADCASTING BOARD OF GOVERNORS PRIVACY ACT REGULATION § 505.3 Procedures for requests... to herself/himself as a request made under the Privacy Act of 1974, as amended (5 U.S.C. 552a) whether or not the individual specifically cites the Privacy Act when making the request. (b) All requests...

  9. 50 CFR 82.16 - Reporting.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...) FINANCIAL ASSISTANCE-WILDLIFE SPORT FISH RESTORATION PROGRAM ADMINISTRATIVE PROCEDURES FOR GRANTS-IN-AID... prescribed by FMC 74-7 or other appropriate referenced Federal Management Circulars cited in § 82.3 of this...

  10. 50 CFR 82.16 - Reporting.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ...) FINANCIAL ASSISTANCE-WILDLIFE SPORT FISH RESTORATION PROGRAM ADMINISTRATIVE PROCEDURES FOR GRANTS-IN-AID... prescribed by FMC 74-7 or other appropriate referenced Federal Management Circulars cited in § 82.3 of this...

  11. 50 CFR 82.16 - Reporting.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...) FINANCIAL ASSISTANCE-WILDLIFE SPORT FISH RESTORATION PROGRAM ADMINISTRATIVE PROCEDURES FOR GRANTS-IN-AID... prescribed by FMC 74-7 or other appropriate referenced Federal Management Circulars cited in § 82.3 of this...

  12. Going, Going, Still There: Using the WebCite Service to Permanently Archive Cited Web Pages

    PubMed Central

    Trudel, Mathieu

    2005-01-01

    Scholars are increasingly citing electronic “web references” which are not preserved in libraries or full text archives. WebCite is a new standard for citing web references. To “webcite” a document involves archiving the cited Web page through www.webcitation.org and citing the WebCite permalink instead of (or in addition to) the unstable live Web page. This journal has amended its “instructions for authors” accordingly, asking authors to archive cited Web pages before submitting a manuscript. Almost 200 other journals are already using the system. We discuss the rationale for WebCite, its technology, and how scholars, editors, and publishers can benefit from the service. Citing scholars initiate an archiving process of all cited Web references, ideally before they submit a manuscript. Authors of online documents and websites which are expected to be cited by others can ensure that their work is permanently available by creating an archived copy using WebCite and providing the citation information including the WebCite link on their Web document(s). Editors should ask their authors to cache all cited Web addresses (Uniform Resource Locators, or URLs) “prospectively” before submitting their manuscripts to their journal. Editors and publishers should also instruct their copyeditors to cache cited Web material if the author has not done so already. Finally, WebCite can process publisher submitted “citing articles” (submitted for example as eXtensible Markup Language [XML] documents) to automatically archive all cited Web pages shortly before or on publication. Finally, WebCite can act as a focussed crawler, caching retrospectively references of already published articles. Copyright issues are addressed by honouring respective Internet standards (robot exclusion files, no-cache and no-archive tags). Long-term preservation is ensured by agreements with libraries and digital preservation organizations. The resulting WebCite Index may also have applications for research assessment exercises, being able to measure the impact of Web services and published Web documents through access and Web citation metrics. PMID:16403724

  13. Designing with figer-reinforced plastics (planar random composites)

    NASA Technical Reports Server (NTRS)

    Chamis, C. C.

    1982-01-01

    The use of composite mechanics to predict the hygrothermomechanical behavior of planar random composites (PRC) is reviewed and described. These composites are usually made from chopped fiber reinforced resins (thermoplastics or thermosets). The hygrothermomechanical behavior includes mechanical properties, physical properties, thermal properties, fracture toughness, creep and creep rupture. Properties are presented in graphical form with sample calculations to illustrate their use. Concepts such as directional reinforcement and strip hybrids are described. Typical data that can be used for preliminary design for various PRCs are included. Several resins and molding compounds used to make PRCs are described briefly. Pertinent references are cited that cover analysis and design methods, materials, data, fabrication procedures and applications.

  14. How-to-Do-It: Diatoms: The Ignored Alga in High School Biology.

    ERIC Educational Resources Information Center

    Hungerford, James J.

    1988-01-01

    Provides historical background, descriptions, uses and basis for identification of diatoms. Explains collection, dry-mount cleaning, and preparation procedures of the algae. Cites additional resources. (RT)

  15. 50 CFR 82.16 - Reporting.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...) FINANCIAL ASSISTANCE-WILDLIFE AND SPORT FISH RESTORATION PROGRAM ADMINISTRATIVE PROCEDURES FOR GRANTS-IN-AID... prescribed by FMC 74-7 or other appropriate referenced Federal Management Circulars cited in § 82.3 of this...

  16. 50 CFR 82.16 - Reporting.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...) FINANCIAL ASSISTANCE-WILDLIFE AND SPORT FISH RESTORATION PROGRAM ADMINISTRATIVE PROCEDURES FOR GRANTS-IN-AID... prescribed by FMC 74-7 or other appropriate referenced Federal Management Circulars cited in § 82.3 of this...

  17. Calculation algorithms for breath-by-breath alveolar gas exchange: the unknowns!

    PubMed

    Golja, Petra; Cettolo, Valentina; Francescato, Maria Pia

    2018-06-25

    Several papers (algorithm papers) describe computational algorithms that assess alveolar breath-by-breath gas exchange by accounting for changes in lung gas stores. It is unclear, however, if the effects of the latter are actually considered in literature. We evaluated dissemination of algorithm papers and the relevant provided information. The list of documents investigating exercise transients (in 1998-2017) was extracted from Scopus database. Documents citing the algorithm papers in the same period were analyzed in full text to check consistency of the relevant information provided. Less than 8% (121/1522) of documents dealing with exercise transients cited at least one algorithm paper; the paper of Beaver et al. (J Appl Physiol 51:1662-1675, 1981) was cited most often, with others being cited tenfold less. Among the documents citing the algorithm paper of Beaver et al. (J Appl Physiol 51:1662-1675, 1981) (N = 251), only 176 cited it for the application of their algorithm/s; in turn, 61% (107/176) of them stated the alveolar breath-by-breath gas exchange measurement, but only 1% (1/107) of the latter also reported the assessment of volunteers' functional residual capacity, a crucial parameter for the application of the algorithm. Information related to gas exchange was provided consistently in the methods and in the results in 1 of the 107 documents. Dissemination of algorithm papers in literature investigating exercise transients is by far narrower than expected. The information provided about the actual application of gas exchange algorithms is often inadequate and/or ambiguous. Some guidelines are provided that can help to improve the quality of future publications in the field.

  18. Survey of Kidney Biopsy Clinical Practice and Training in the United States.

    PubMed

    Yuan, Christina M; Nee, Robert; Little, Dustin J; Narayan, Rajeev; Childs, John M; Prince, Lisa K; Raghavan, Rajeev; Oliver, James D

    2018-05-07

    Practicing clinical nephrologists are performing fewer diagnostic kidney biopsies. Requiring biopsy procedural competence for graduating nephrology fellows is controversial. An anonymous, on-line survey of all Walter Reed training program graduates ( n =82; 1985-2017) and all United States nephrology program directors ( n =149; August to October of 2017), regarding kidney biopsy practice and training, was undertaken. Walter Reed graduates' response and completion rates were 71% and 98%, respectively. The majority felt adequately trained in native kidney biopsy (83%), transplant biopsy (82%), and tissue interpretation (78%), with no difference for ≤10 versus >10 practice years. Thirty-five percent continued to perform biopsies (13% did ≥10 native biopsies/year); 93% referred at least some biopsies. The most common barriers to performing biopsy were logistics (81%) and time (74%). Program director response and completion rates were 60% and 77%. Seventy-two percent cited ≥1 barrier to fellow competence. The most common barriers were logistics (45%), time (45%), and likelihood that biopsy would not be performed postgraduation (41%). Fifty-one percent indicated that fellows should not be required to demonstrate minimal procedural competence in biopsy, although 97% agreed that fellows should demonstrate competence in knowing/managing indications, contraindications, and complications. Program directors citing ≥1 barrier or whose fellows did <50 native biopsies/year in total were more likely to think that procedural competence should not be required versus those citing no barriers ( P =0.02), or whose fellows performed ≥50 biopsies ( P <0.01). Almost two-thirds of graduate respondents from a single military training program no longer perform biopsy, and 51% of responding nephrology program directors indicated that biopsy procedural competence should not be required. These findings should inform discussion of kidney biopsy curriculum requirements. Copyright © 2018 by the American Society of Nephrology.

  19. 50 CFR 23.90 - What are the criteria for listing species in Appendix III?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... ENDANGERED SPECIES OF WILD FAUNA AND FLORA (CITES) Lists of Species § 23.90 What are the criteria for listing... Secretariat notifies the Parties of the request. (c) Criteria for listing. For a Party to list a species in... the annotation. (e) U.S. procedure. The procedure to list a species native to the United States in...

  20. Citation classics in nursing journals: the top 50 most frequently cited articles from 1956 to 2011.

    PubMed

    Wong, Eliza L Y; Tam, Wilson W S; Wong, Faye C Y; Cheung, Annie W L

    2013-01-01

    Assessing the impact of individual journal articles provides information for understanding trends in science and translation of findings on practice. Citation analysis is an important way to highlight the contributions of individual author/investigator and journals on nursing practice. The purpose of this study was to identify the most frequently cited articles published in nursing journals from 1956 to 2011. The Science Citation Index Expanded and Social Sciences Citation Index were searched for citations through 2011 to articles published in the 89 nursing journals listed on the Journal Citation Reports (2010 edition). The number of citations, topic, countries, and institutions of origin based on the first author affiliation, year of publication, study design, publishing journal, journal country, and journal impact factor were noted. The most frequently cited articles published in the 89 nursing journals from 1956 to 2011 were identified. The top 50 most frequently cited articles were published in 10 nursing journals between 1970 and 2005. The top cited article received 784 citations. The most common topics were methodology for qualitative studies, validation procedures for tool development, and nursing care and practices in cancer and mental health. The most common study designs were reviews including meta-analysis and instrument validation. Most of the top 50 cited articles were published from 1986 to 1995. The findings provide insights into priorities and trends in nursing research and translational science.

  1. 29 CFR 6.7 - Appearances.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... default judgment cites alleged procedural irregularities in the proceeding below and not the merits of the... a hearing shall not be deemed to be a waiver of the right to be served with a copy of the...

  2. 15 CFR 904.400 - Purpose and scope.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Written Warnings § 904.400 Purpose and scope. This subpart sets forth the policy and procedures governing... penalty or initiating criminal prosecution for violation of any of the laws cited in § 904.1(c). ...

  3. Three-phase Discussion Sessions.

    ERIC Educational Resources Information Center

    Karr, M. C.; And Others

    1988-01-01

    Describes the procedures, organizational pattern and design of basic soils course used by teaching assistants. Cites studies which support small-group discussion for promoting higher levels of intellectual functioning. Presents tables showing survey evaluation results of this method. (RT)

  4. SRC-I demonstration plant analytical laboratory methods manual. Final technical report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Klusaritz, M.L.; Tewari, K.C.; Tiedge, W.F.

    1983-03-01

    This manual is a compilation of analytical procedures required for operation of a Solvent-Refined Coal (SRC-I) demonstration or commercial plant. Each method reproduced in full includes a detailed procedure, a list of equipment and reagents, safety precautions, and, where possible, a precision statement. Procedures for the laboratory's environmental and industrial hygiene modules are not included. Required American Society for Testing and Materials (ASTM) methods are cited, and ICRC's suggested modifications to these methods for handling coal-derived products are provided.

  5. The ERTS-1 investigation (ER-600): A compendium of analysis results of the utility of ERTS-1 data for land resources management

    NASA Technical Reports Server (NTRS)

    Erb, R. B.

    1974-01-01

    The results of the ERTS-1 investigations conducted by the Earth Observations Division at the NASA Lyndon B. Johnson Space Center are summarized in this report, which is an overview of documents detailing individual investigations. Conventional image interpretation and computer-aided classification procedures were the two basic techniques used in analyzing the data for detecting, identifying, locating, and measuring surface features related to earth resources. Data from the ERTS-1 multispectral scanner system were useful for all applications studied, which included agriculture, coastal and estuarine analysis, forestry, range, land use and urban land use, and signature extension. Percentage classification accuracies are cited for the conventional and computer-aided techniques.

  6. Synergistic effect of business reputation in the result of application of innovations on the enterprises of the transport industry

    NASA Astrophysics Data System (ADS)

    Doroshin, Ivan; Diakonova, Sophia; Sharapova, Elena

    2017-10-01

    In the conditions of dynamic innovative development of the enterprises of transport branch along with maintaining economic instability it has become necessary to consider not only traditional factors at assessment of efficiency of activity and cost of business, but also consider business reputation factor, which depends on the level of innovative development of the enterprise and generates effect of synergy. Paper considers the concept of synergistic effect. Classification of types of synergistic effects is cited. Estimation procedure for influence of the technical level and innovative development of transport enterprises on the value of business reputation is considered. Functional dependence of the cost of business reputation on the innovative development and synergistic effect is defined.

  7. Surgical Education's 100 Most Cited Articles: A Bibliometric Analysis.

    PubMed

    Matthews, Alexander H; Abdelrahman, Tarig; Powell, Arfon G M T; Lewis, Wyn G

    2016-01-01

    Bibliometric analysis highlights the key topics and publications, which have shaped surgical education. Here, the 100 most cited articles in the arena of surgical education were analyzed. Thomson Reuters Web of Science was interrogated using the keyword search terms "surgery" and ("learning" or "skills" or "competence" or "assessment" or "training" or "procedure-based assessments" or "performance" or "technical skills" or "curriculum" or "education" or "mentoring"] to identify all English language full articles, and the 100 most cited articles were analyzed by topic, journal, author, year, institution, and country of origin. A total of 403,733 eligible articles were returned and the median citation number was 164 (range: 107-1018). The most cited article (by Seymour, Yale University School of Medicine, Annals of Surgery, 1018 citations) focused on the use of virtual reality surgical simulation training. Annals of Surgery published the highest number of articles and received the most citations (n = 16, 3715 citations). The countries with the greatest number of publications were the USA (n = 45), Canada (n = 19), and the UK (n = 18). The commonest topics included simulation (n = 45) and assessment of clinical competence (n = 40). Surgical skill acquisition and assessment was the area of focus of 85% of the most cited contemporary articles, and this study provides the most cited references, serving as a guide as to what makes a citable published work in the field of surgical education. Copyright © 2016 Association of Program Directors in Surgery. Published by Elsevier Inc. All rights reserved.

  8. "It All Started with Descartes."

    ERIC Educational Resources Information Center

    Clark, Todd

    1987-01-01

    Cites examples of private attacks and governmental restrictions on academic freedom. Contends that teachers must explicitly teach the importance of free inquiry in an open society; and that school districts must have written procedures in place for dealing with complaints. (JDH)

  9. Sleeping beauties cited in patents: Is there also a dormitory of inventions?

    PubMed

    van Raan, Anthony F J

    2017-01-01

    A 'Sleeping Beauty in Science' is a publication that goes unnoticed ('sleeps') for a long time and then, almost suddenly, attracts a lot of attention ('is awakened by a prince'). In our foregoing study we found that roughly half of the Sleeping Beauties are application-oriented and thus are potential Sleeping Innovations. In this paper we investigate a new topic: Sleeping Beauties that are cited in patents. In this way we explore the existence of a dormitory of inventions. To our knowledge this is the first study of this kind. We investigate the time lag between publication of the Sleeping Beauty and the first citation by a patent. We find that patent citation may occur before or after the awakening and that the depth of the sleep, i.e., citation rate during the sleeping period, is no predictor for later scientific or technological impact of the Sleeping Beauty. A surprising finding is that Sleeping Beauties are significantly more cited in patents than 'normal' papers. Inventor-author self-citations relations occur only in a small minority of the Sleeping Beauties that are cited in patents, but other types of inventor-author links occur more frequently. We develop an approach in different steps to explore the cognitive environment of Sleeping Beauties cited in patents. First, we analyze whether they deal with new topics by measuring the time-dependent evolution in the entire scientific literature of the number of papers related to both the precisely defined topics as well as the broader research theme of the Sleeping Beauty during and after the sleeping time. Second, we focus on the awakening by analyzing the first group of papers that cites the Sleeping Beauty. Third, we create concept maps of the topic-related and the citing papers for a time period immediately following the awakening and for the most recent period. Finally, we make an extensive assessment of the cited and citing relations of the Sleeping Beauty. We find that tunable co-citation analysis is a powerful tool to discover the prince(s) and other important application-oriented work directly related to the Sleeping Beauty, for instance papers written by authors who cite Sleeping Beauties in both the patents of which they are the inventors, as well as in their scientific papers.

  10. The Search for Adult Assessment Procedures.

    ERIC Educational Resources Information Center

    Usnick, Virginia; Babbitt, Beatrice C.

    1993-01-01

    Reviewed 12 currently available mathematics assessment tools to determine whether they would be appropriate for use in a college-level mathematics clinic. Tests were assigned to two domains: cognitive and mathematical content. Major deficiencies of the tests are cited. (Contains 15 references.) (MDH)

  11. Redress of Grievances.

    ERIC Educational Resources Information Center

    Davies, Helen C.; Davies, Robert E.

    The status of women in higher education, sex discrimination, laws providing protection against sex descrimination, grievance procedures, and difficulties involved in filing complaints are addressed. Empirical evidence is cited that illustrates discrimination against women at the hiring level in the scientific academic community. To substantiate…

  12. Systematic Desensitization in Group Counseling Settings: An Overview

    ERIC Educational Resources Information Center

    Mayton, Daniel M., II; Atkinson, Donald R.

    1974-01-01

    This article summarizes research on systematic desensitization applied in group settings. Guidelines for use of group desensitization by college counselors are developed, and relevant sources regarding procedural variations cited. The need for research on group desensitization parameters is discussed. (Author)

  13. Automatic Indexing Using Term Discrimination and Term Precision Measurements

    ERIC Educational Resources Information Center

    Salton, G.; And Others

    1976-01-01

    These two indexing systems are briefly described and experimental evidence is cited showing that a combination of both theories produces better retrieval performance than either one alone. Appropriate conclusions are reached concerning viable automatic indexing procedures usable in practice. (Author)

  14. The DEDS: DSTO’s Environmental-Data Server for Research Applications

    DTIC Science & Technology

    2013-07-01

    AccuWeather.com, 2010. Available from: http:// www.accuweather.com/ [cited 15 June 2010]. 44. National Oceanic and Atmospheric Administration, /data/gfs- avn ...hi. Available from: http://nomads.ncdc.noaa.gov/data/gfs- avn -hi/ [cited 15 June 2010]. 45. Wang, Y., L.R. Leung, J.L. McGregor, D.-K. Lee, W.-C

  15. A detailed procedure for the use of small-scale photography in land use classification

    NASA Technical Reports Server (NTRS)

    Vegas, P. L.

    1974-01-01

    A procedure developed to produce accurate land use maps from available high-altitude, small-scale photography in a cost-effective manner is presented. An alternative procedure, for use when the capability for updating the resultant land use map is not required, is also presented. The technical approach is discussed in detail, and personnel and equipment needs are analyzed. Accuracy percentages are listed, and costs are cited. The experiment land use classification categories are explained, and a proposed national land use classification system is recommended.

  16. Defining and assessing wisdom: a review of the literature.

    PubMed

    Bangen, Katherine J; Meeks, Thomas W; Jeste, Dilip V

    2013-12-01

    With increasing longevity and a growing focus on successful aging, there has been a recent growth of research designed to operationalize and assess wisdom. We aimed to (1) investigate the degree of overlap among empirical definitions of wisdom, (2) identify the most commonly cited wisdom subcomponents, (3) examine the psychometric properties of existing assessment instruments, and (4) investigate whether certain assessment procedures work particularly well in tapping the essence of subcomponents of the various empirical definitions. We searched PsychINFO-indexed articles published through May 2012 and their bibliographies. Studies were included if they were published in a peer-reviewed journal and (1) proposed a definition of wisdom or (2) discussed the development or validation of an instrument designed to assess wisdom. Thirty-one articles met inclusion criteria. Despite variability among the 24 reviewed definitions, there was significant overlap. Commonly cited subcomponents of wisdom included knowledge of life, prosocial values, self-understanding, acknowledgment of uncertainty, emotional homeostasis, tolerance, openness, spirituality, and sense of humor. Published reports describing the psychometric properties of nine instruments varied in comprehensiveness but most measures were examined for selected types of reliability and validity, which were generally acceptable. Given limitations of self-report procedures, an approach integrating multiple indices (e.g., self-report and performance-based measures) may better capture wisdom. Significant progress in the empirical study of wisdom has occurred over the past four decades; however, much needs to be done. Future studies with larger, more diverse samples are needed to determine the generalizability, usefulness, and clinical applicability of these definitions and assessment instruments. Such work will have relevance for the fields of geriatrics, psychiatry, psychology, sociology, education, and public health, among others. Copyright © 2013 American Association for Geriatric Psychiatry. All rights reserved.

  17. Chemometrics.

    ERIC Educational Resources Information Center

    Kowalski, Bruce R.

    1980-01-01

    Outlines recent advances in the development of the field of chemometrics, defined as the application of mathematical and statistical methods to chemical measurements. Emphasizes applications in the field. Cites 288 references. (CS)

  18. Liability for Student Workers.

    ERIC Educational Resources Information Center

    Tryon, Jonathan S.

    1994-01-01

    Examines liability issues for academic libraries=FE student workers. Discussion includes staff training; hiring practices; supervision; negligence; emergency procedures; the use of reasonable care; and knowledge of library rules. Specific nonlibrary liability cases are cited as examples of the importance of employee screening, training, and danger…

  19. A Computer-Managed Instruction Support System for Large Group Individualized Instruction.

    ERIC Educational Resources Information Center

    Countermine, Terry; Singh, Jane M.

    1977-01-01

    The Pennsylvania State University College of Education's Instruction Support System (ISS) was developed to manage the logistical operation of large group individualized competency-based instruction. Software and hardware charting, operational procedures, and data from student opinion questionnaires are cited. (RAO)

  20. Using Biblio-Link...For Those Other Databases.

    ERIC Educational Resources Information Center

    Joy, Albert

    1989-01-01

    Sidebar describes the use of the Biblio-Link software packages to download citations from online databases and convert them into a form that can be automatically uploaded into a Pro-Cite database. An example of this procedure using DIALOG2 is given. (CLB)

  1. 50 CFR 82.13 - Ownership of property.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ...) FINANCIAL ASSISTANCE-WILDLIFE SPORT FISH RESTORATION PROGRAM ADMINISTRATIVE PROCEDURES FOR GRANTS-IN-AID... assignment of title and any compensations consistent with the terms of Federal Management Circular 74-7 or other appropriate referenced Federal Management Circulars cited in § 82.3 of this part. ...

  2. 50 CFR 82.13 - Ownership of property.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...) FINANCIAL ASSISTANCE-WILDLIFE SPORT FISH RESTORATION PROGRAM ADMINISTRATIVE PROCEDURES FOR GRANTS-IN-AID... assignment of title and any compensations consistent with the terms of Federal Management Circular 74-7 or other appropriate referenced Federal Management Circulars cited in § 82.3 of this part. ...

  3. 50 CFR 82.13 - Ownership of property.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...) FINANCIAL ASSISTANCE-WILDLIFE SPORT FISH RESTORATION PROGRAM ADMINISTRATIVE PROCEDURES FOR GRANTS-IN-AID... assignment of title and any compensations consistent with the terms of Federal Management Circular 74-7 or other appropriate referenced Federal Management Circulars cited in § 82.3 of this part. ...

  4. Citation analysis of Minnesota Department of Health official publications and journal articles: a needs assessment for the RN Barr Library.

    PubMed

    Rethlefsen, Melissa L

    2007-07-01

    The paper describes the information needs of a state public health agency, compares needs to its library's collection, and evaluates collection development policy accordingly. A citation analysis of journal articles authored by Minnesota Department of Health staff as well as official publications from 2002 to 2004 was conducted. Fifty-six publications fitting the criteria for inclusion in the study were identified using PubMed and library records. Information on each cited reference was recorded, including reference type, relative age of citation, and journal name, if applicable. The library's collection and collection development policies were analyzed in regard to the results. As expected, journals were the most heavily cited format: 63% (n = 897) of all citations were to journal articles. Most cited materials were between 2 and 5 years old. The 897 journal citations represented 265 different journals. The top 10 cited journals (4% of all titles) accounted for 36% (n = 320) of all citations; 62% (n = 320) of journals were cited only once. Of the total journals cited, the library subscribed to 70% (n = 627). Overall, no large gaps appeared in the RN Barr Library's journal collection. The analysis confirms that the library's collections budget for serials and books reflects the cited use of these materials.

  5. Generation of three wide frequency bands within a single white-light cavity

    NASA Astrophysics Data System (ADS)

    Othman, Anas; Yevick, David; Al-Amri, M.

    2018-04-01

    We theoretically investigate the double-Λ scheme inside a Fabry-Pérot cavity employing a weak probe beam and two strong driving fields together with an incoherent pumping mechanism. By generating analytical expressions for the susceptibility and applying the white-light cavity conditions, we devise a procedure that reaches the white-light condition at a smaller gas density than the values typically cited in similar previous studies. Further, when the intensities of the two driving fields are equal, a single giant white band is obtained, while for unequal driving fields three white bands can be present in the cavity. Two additional techniques are then advanced for generating three white bands and a method is described for displacing the center frequency of the bands. Finally, some potential applications are suggested.

  6. Highly cited articles in health care sciences and services field in Science Citation Index Expanded. A bibliometric analysis for 1958 - 2012.

    PubMed

    Hsu, Y-H E; Ho, Y-S

    2014-01-01

    This study aimed to identify and analyze characteristics of highly cited articles published in the Web of Science category of health care sciences and services from 1958 to 2012. Articles that have been cited at least 100 times were assessed regarding publication outputs, distribution of outputs in journals, publications of authors, institutions, countries as well as citation life cycles of the articles with the highest total citations since its publication up to 2012 and the highest citations in 2012. Six bibliometric indicators were used to evaluate source countries, institutions, and authors. Total citations from the time the articles were first published to the end of 2012 and citations in 2012 only were applied. Additionally, Y-index was applied to evaluate publication characteristics of authors. A high percentage of authors had the same numbers of first author and corresponding author status of highly cited articles in health care sciences and services field. RESULTS showed that 890 of the most highly referenced articles, published between 1977 and 2009, had been cited at least 100 times. Medical Care and Journal of General Internal Medicine published the most highly cited articles. The United States produced 76% of highly cited articles and also published the most number of independent, internationally collaborative, first authored, corresponding authored, and single author highly cited articles. The Harvard University was the most productive institute and was number one for the total highly cited articles, inter-institutionally collaborative articles, single institution articles, first author articles, and corresponding author articles. The application of quantitative techniques in the analysis of highly cited articles can improve the researchers' understanding of the directions in health care sciences and services field. Y-index is useful for the evaluation of contributing authors.

  7. The 100 most-cited original articles in cardiac computed tomography: A bibliometric analysis.

    PubMed

    O'Keeffe, Michael E; Hanna, Tarek N; Holmes, Davis; Marais, Olivia; Mohammed, Mohammed F; Clark, Sheldon; McLaughlin, Patrick; Nicolaou, Savvas; Khosa, Faisal

    2016-01-01

    Bibliometric analysis is the application of statistical methods to analyze quantitative data about scientific publications. It can evaluate research performance, author productivity, and manuscript impact. To the best of our knowledge, no bibliometric analysis has focused on cardiac computed tomography (CT). The purpose of this paper was to compile a list of the 100 most-cited articles related to cardiac CT literature using Scopus and Web of Science (WOS). A list of the 100 most-cited articles was compiled by order of citation frequency, as well a list of the top 10 most-cited guideline and review articles and the 20 most-cited articles of the years 2014-2015. The database of 100 most-cited articles was analyzed to identify characteristics of highly cited publications. For each manuscript, the number of authors, study design, size of patient cohort and departmental affiliations were cataloged. The 100 most-cited articles were published from 1990 to 2012, with the majority (53) published between 2005 and 2009. The total number of citations varied from 3354 to 196, and the number of citations per year varied from 9.5 to 129.0 with a median and mean of 30.9 and 38.7, respectively. The majority of publications had a study patients sample size of 200 patients or less. The USA and Germany were the nations with the highest number of frequently cited publications. This bibliometric analysis provides insights on the most-cited articles published on the subject of cardiac CT and calcium volume, thus helping to characterize the field and guide future research. Copyright © 2016 Society of Cardiovascular Computed Tomography. Published by Elsevier Inc. All rights reserved.

  8. Early Citability of Data vs Peer-Review like Data Publishing Procedures

    NASA Astrophysics Data System (ADS)

    Stockhause, Martina; Höck, Heinke; Toussaint, Frank; Lautenschlager, Michael

    2014-05-01

    The World Data Center for Climate (WDCC) hosted at the German Climate Computing Center (DKRZ) was one of the first data centers, which established a peer-review like data publication procedure resulting in DataCite DOIs. Data in the long-term archive (LTA) is diligently reviewed by data managers and data authors to grant high quality and widely reusability of the published data. This traditional data publication procedure for LTA data bearing DOIs is very time consuming especially for WDCC's high data volumes of climate model data in the order of multiple TBytes. Data is shared with project members and selected scientists months before the data is long-term archived. The scientific community analyses and thus reviews the data leading to data quality improvements. Scientists wish to cite these unstable data in scientific publications before the long-term archiving and the thorough data review process are finalized. A concept for early preprint DOIs for shared but not yet long-term archived data is presented. Requirements on data documentation, persistence and quality and use cases for preprint DOIs within the data life-cycle are discussed as well as questions of how to document the differences of the two DOI types and how to relate them to each other with the recommendation to use LTA DOIs in citations. WDCC wants to offer an additional user service for early citations of data of basic quality without compromising the LTA DOIs, i.e. WDCC's standard DOIs, as trustworthy indicator for high quality data. Referencing Links: World Data Center for Climate (WDCC): http://www.wdc-climate.de German Climate Computing Center (DKRZ): http://www.dkrz.de DataCite: http://datacite.org

  9. Misrepresentation of publications by radiology residency applicants: is it really a problem?

    PubMed

    Eisenberg, Ronald L; Cunningham, Meredith; Kung, Justin W; Slanetz, Priscilla J

    2013-03-01

    The aim of this study was to determine whether the previous relatively high rate of misrepresentation of publications is still a problem with current applicants for radiology residency. The publications submitted by a sample of 300 applicants for a radiology residency in 2011 were assessed using PubMed and an extensive Internet search to verify whether the articles were in print and had the applicants listed as authors and in the same positions of authorship. Whether the applicants graduated from US or international medical schools was recorded. Of the 138 applicants (46.0%) who cited 1 or more publications, there were 5 misrepresentations (3.6%). These included 1 article not found in the cited journal, 1 journal that could not be found, 1 article in which the applicant was not listed as an author, and 2 instances in which the applicants were not in the same positions of authorship (listed as lead authors but actually second authors). The misrepresentation rate was 1.9% among US graduates and 8.8% among graduates of international medical schools. The low rate of misrepresentation of publications, especially among graduates of US medical schools, does not seem to warrant spending the time to check the citations of journal articles of all applicants for radiology residency positions. Nevertheless, it is reasonable to request that applicants bring to their interviews a copy of each cited article and to assess their knowledge of all other listed research activities. Copyright © 2013 American College of Radiology. Published by Elsevier Inc. All rights reserved.

  10. Méthodologie de l'extraction des hydrocarbures aromatiques polycycliques. Application à des sédiments de la lagune de Bizerte (Tunisie)Methodology of extraction of polycyclic aromatic hydrocarbons. Application to sediment from the Bizerte Lagoon (Tunisia)

    NASA Astrophysics Data System (ADS)

    Mzoughi, Nadia; Hellal, Fayçal; Dachraoui, Mohamed; Villeneuve, Jean-Pierre; Cattini, Chantal; de Mora, Stephen J.; El Abed, Amor

    2002-09-01

    The marine environment is very complex, with several important chemical, biological, and sedimentological interactions. Sediments constitute a reservoir for numerous pollutants, including polycyclic aromatic hydrocarbons (PAHs). PAHs are known by their mutagenic and/or carcinogenic effect. This study evaluates contamination levels in Bizerte Lagoon with respect to PAHs. The extraction efficiency of PAHs from sediment has been evaluated using Soxhlet or ultrasonic procedures, based on the recovery of an internal standard (9,10-dihydroanthracene). Several PAHs were found, including sixteen that are reported in the priority list of pollutants of the US Environmental Protection Agency (EPA). PAHs analysis was carried out by GC-FID and GC-MS for 16 samples sampled in two seasons: summer and winter. Results permit an assessment of PAHs pollution in the Bizerte Lagoon. To cite this article: N. Mzoughi et al., C. R. Geoscience 334 (2002) 893-901.

  11. Groundwater technical procedures of the U.S. Geological Survey

    USGS Publications Warehouse

    Cunningham, William L.; Schalk, Charles W.

    2011-01-01

    A series of groundwater technical procedures documents (GWPDs) has been released by the U.S. Geological Survey, Water-Resources Discipline, for general use by the public. These technical procedures were written in response to the need for standardized technical procedures of many aspects of groundwater science, including site and measuring-point establishment, measurement of water levels, and measurement of well discharge. The techniques are described in the GWPDs in concise language and are accompanied by necessary figures and tables derived from cited manuals, reports, and other documents. Because a goal of this series of procedures is to remain current with the state of the science, and because procedures change over time, this report is released in an online format only. As new procedures are developed and released, they will be linked to this document.

  12. 48 CFR 231.703 - Requirements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Requirements. 231.703... OF DEFENSE GENERAL CONTRACTING REQUIREMENTS CONTRACT COST PRINCIPLES AND PROCEDURES Contracts With Nonprofit Organizations 231.703 Requirements. Under 10 U.S.C. 2249, the costs cited in 231.205-22(a) are...

  13. 48 CFR 231.703 - Requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Requirements. 231.703... OF DEFENSE GENERAL CONTRACTING REQUIREMENTS CONTRACT COST PRINCIPLES AND PROCEDURES Contracts With Nonprofit Organizations 231.703 Requirements. Under 10 U.S.C. 2249, the costs cited in 231.205-22(a) are...

  14. 48 CFR 231.703 - Requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Requirements. 231.703... OF DEFENSE GENERAL CONTRACTING REQUIREMENTS CONTRACT COST PRINCIPLES AND PROCEDURES Contracts With Nonprofit Organizations 231.703 Requirements. Under 10 U.S.C. 2249, the costs cited in 231.205-22(a) are...

  15. 48 CFR 231.703 - Requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Requirements. 231.703... OF DEFENSE GENERAL CONTRACTING REQUIREMENTS CONTRACT COST PRINCIPLES AND PROCEDURES Contracts With Nonprofit Organizations 231.703 Requirements. Under 10 U.S.C. 2249, the costs cited in 231.205-22(a) are...

  16. Women in Canada: A Bibliography 1965-1982.

    ERIC Educational Resources Information Center

    Mazur, Carol, Comp.; Pepper, Sheila, Comp.

    Designed to assist research in the field of Canadian women's studies, this bibliography cites books, articles, pamphlets, theses, and government publications published between 1965 and 1982. Following an introduction which describes document selection procedure and organization of materials, more than 2,000 resources are arranged alphabetically…

  17. 32 CFR 293.6 - Procedures.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... public Internet website. (8) Coordinates with other DoD Components, other members of the Intelligence... forwards the report to the Directorate for Freedom of Information and Security Review, Washington... FOIA and the Privacy Act. Not all requesters will be knowledgeable of the appropriate act to cite when...

  18. 50 CFR 82.13 - Ownership of property.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...) FINANCIAL ASSISTANCE-WILDLIFE AND SPORT FISH RESTORATION PROGRAM ADMINISTRATIVE PROCEDURES FOR GRANTS-IN-AID... assignment of title and any compensations consistent with the terms of Federal Management Circular 74-7 or other appropriate referenced Federal Management Circulars cited in § 82.3 of this part. ...

  19. 50 CFR 82.13 - Ownership of property.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...) FINANCIAL ASSISTANCE-WILDLIFE AND SPORT FISH RESTORATION PROGRAM ADMINISTRATIVE PROCEDURES FOR GRANTS-IN-AID... assignment of title and any compensations consistent with the terms of Federal Management Circular 74-7 or other appropriate referenced Federal Management Circulars cited in § 82.3 of this part. ...

  20. Tri-Service Procedural Guidelines for Ecological Risk Assessments. Volume 1.

    DTIC Science & Technology

    1996-05-01

    appearance of product changes pH and a pH sensitive dye is present in the medium), by change in turbidity, or by the production of a precipitate or chemical...project has been the development of procedural guidelines for ecological risk assessment. The product of this effort will maximize the transfer of...constitute an official endorsement of any commercial products . This report may not be cited for the purpose of advertisement. This report has been

  1. Using bibliometrics to demonstrate the value of library journal collections

    PubMed Central

    Belter, Christopher W; Kaske, Neal K

    2016-01-01

    Although cited reference studies are common in the library and information science literature, they are rarely performed in non-academic institutions or in the atmospheric and oceanic sciences. In this paper, we analyze over 400,000 cited references made by authors affiliated with the National Oceanic and Atmospheric Administration between 2009 and 2013. Our results suggest that these methods can be applied to research libraries in a variety of institutions, that the results of analyses performed at one institution may not be applicable to other institutions, and that cited reference analyses should be periodically updated to reflect changes in authors’ referencing behavior. PMID:27453584

  2. 48 CFR 4.201 - Procedures.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... copy to each accounting and finance office (funding office) whose funds are cited in the contract; (d) When the contract is not assigned for administration but contains a Cost Accounting Standards clause... “FOR COST ACCOUNTING STANDARDS ADMINISTRATION ONLY” (see 30.601(b)); (e) Provide one copy of each...

  3. Clarification to "Examining Rater Errors in the Assessment of Written Composition with a Many-Faceted Rasch Model."

    ERIC Educational Resources Information Center

    Englehard, George, Jr.

    1996-01-01

    Data presented in figure three of the article cited may be misleading in that the automatic scaling procedure used by the computer program that generated the histogram highlighted spikes that would look different with different histogram methods. (SLD)

  4. 49 CFR Appendix D to Part 236 - Independent Review of Verification and Validation

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... standards. (f) The reviewer shall analyze all Fault Tree Analyses (FTA), Failure Mode and Effects... for each product vulnerability cited by the reviewer; (4) Identification of any documentation or... not properly followed; (6) Identification of the software verification and validation procedures, as...

  5. Evaluations of the Overjustification Effect

    ERIC Educational Resources Information Center

    Peters, Kerri P.; Vollmer, Timothy R.

    2014-01-01

    The utility of reinforcement-based procedures has been well established in the behavior analysis literature and is commonly used in educational settings. However, the overjustification effect is one commonly cited criticism of programs that use tangible items as reinforcers. In the current studies, we evaluated the effects of tangible rewards…

  6. Renal denervation: a new therapeutic approach for resistant hypertension.

    PubMed

    Cao, Longxing; Fu, Qiang; Wang, Binghui; Li, Zhiliang

    2014-01-01

    To review the advances in studies on renal denervation. References concerning renal denervation and resistant hypertension cited in this review were collected from PubMed published in English and those of renal denervation devices from official websites of device manufacturers up to January 2014. Articles with keywords "renal denervation" and "resistant hypertension" were selected. Renal and systemic sympathetic overactivity plays an important role in pathology of hypertension as well as other diseases characterized by sympathetic overactivity. Renal denervation is a new, catheter based procedure to reduce renal and systemic sympathetic overactivity by disruption of renal sympathetic efferent and afferent nerves through radiofrequency or ultrasound energy delivered to the endoluminal surface of both renal arteries. Although several studies have shown the efficacy and safety of renal denervation in the treatment of resistant hypertension and the potential benefit of the procedure in other diseases, Symplicity HTN 3 study, the most rigorous clinical trial of renal denervation to date, failed to meet its primary endpoint. The procedure also has other limitations such as the lack of long term, efficacy and safety data and the lack of the predictors for the blood pressure lowering response and nonresponse to the procedure. An overview of current renal denervation devices holding Conformité Européenne mark is also included in this review. Renal denervation is a promising therapeutic approach in the management of resistant hypertension and other diseases characterized by sympathetic overactivity. In its early stage of clinical application, the efficacy of the procedure is still controversial. Large scale, blind, randomized, controlled clinical trials are still necessary to address the limitations of the procedure.

  7. 32 CFR 636.34 - Restraint systems.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... ensuring the use of seat belts, shoulder restraints, and child restraining systems when applicable and may... for ensuring that their seat belts/shoulder restraints are used when applicable and may be cited for...

  8. 32 CFR 636.34 - Restraint systems.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... ensuring the use of seat belts, shoulder restraints, and child restraining systems when applicable and may... for ensuring that their seat belts/shoulder restraints are used when applicable and may be cited for...

  9. Behavioral Assessment Instruments, Techniques, and Procedures: Summary and Annotated Bibliography.

    ERIC Educational Resources Information Center

    Shorkey, Clayton T.; Williams, Harry

    This annotated bibliography cites 223 articles related to behavioral assessment reported in 18 professional journals between January 1960 and Spring 1976. A summary and a reference grouping of the articles are included to allow for identification of articles related to (1) electromechanical devices used in identification, measurement, and storage…

  10. 46 CFR 201.75 - Petitions-general.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false Petitions-general. 201.75 Section 201.75 Shipping... PROCEDURE Formal Proceedings, Notice, Pleadings, Replies (Rule 7) § 201.75 Petitions—general. All petitions... relied upon, and the relief sought, and shall cite the authority upon which the petition rests. The...

  11. Penetrating School Strata Through Career Education (Grades 7 and 8).

    ERIC Educational Resources Information Center

    Bristol Public Schools, CT.

    The career education curriculum guide for grades seven and eight contains activities that can be integrated with existing curriculum. For each activity, career education objectives are cited together with goals, materials, procedures, anticipated results, and evaluation. Career education activities are presented in the following areas: art,…

  12. "Madame Bovary": Illusion and Reality. [Lesson Plan].

    ERIC Educational Resources Information Center

    Carangelo, Audrey

    Based on Gustave Flaubert's novel "Madame Bovary," this lesson plan presents activities designed to help students explore the theme of "illusion versus reality" in the novel; identify and list alternate themes in the novel; and cite specific examples of illusion versus reality from the novel. It includes objectives, materials, procedures,…

  13. No Room at the Top: Sex Discrimination in Higher Education.

    ERIC Educational Resources Information Center

    Sorgman, Margo

    Data are presented on women in higher education, along with information on federal legislation to eliminate sex discrimination, issues concerning redressing employment discrimination, specific problems with legislative procedures and enforcement of legislation, and case studies that highlight some of the processes involved. Evidence is cited that…

  14. Piaget for Chemists: Explaining What "Good" Students Cannot Understand

    ERIC Educational Resources Information Center

    Herron, J. Dudley

    1975-01-01

    Attributes learning difficulties in introductory chemistry to the thesis that many students have not reached the formal operations level of intellectual development. Cites instances to support this thesis, outlines an instructional procedure to overcome the difficulty, and presents a list of competencies that can be expected of these students. (GS)

  15. 45 CFR 1210.3-4 - Initiation of termination.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... COMMUNITY SERVICE VISTA TRAINEE DESELECTION AND VOLUNTEER EARLY TERMINATION PROCEDURES VISTA Volunteer Early... has reason to believe that a Volunteer is subject to termination for any of the grounds cited in § 1210.3-1, an ACTION staff member will discuss the matter with the Volunteer. If, after the discussion...

  16. 45 CFR 1210.3-4 - Initiation of termination.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... COMMUNITY SERVICE VISTA TRAINEE DESELECTION AND VOLUNTEER EARLY TERMINATION PROCEDURES VISTA Volunteer Early... has reason to believe that a Volunteer is subject to termination for any of the grounds cited in § 1210.3-1, an ACTION staff member will discuss the matter with the Volunteer. If, after the discussion...

  17. 45 CFR 1210.3-4 - Initiation of termination.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... COMMUNITY SERVICE VISTA TRAINEE DESELECTION AND VOLUNTEER EARLY TERMINATION PROCEDURES VISTA Volunteer Early... has reason to believe that a Volunteer is subject to termination for any of the grounds cited in § 1210.3-1, an ACTION staff member will discuss the matter with the Volunteer. If, after the discussion...

  18. 45 CFR 1210.3-4 - Initiation of termination.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... COMMUNITY SERVICE VISTA TRAINEE DESELECTION AND VOLUNTEER EARLY TERMINATION PROCEDURES VISTA Volunteer Early... has reason to believe that a Volunteer is subject to termination for any of the grounds cited in § 1210.3-1, an ACTION staff member will discuss the matter with the Volunteer. If, after the discussion...

  19. 45 CFR 1210.3-4 - Initiation of termination.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... COMMUNITY SERVICE VISTA TRAINEE DESELECTION AND VOLUNTEER EARLY TERMINATION PROCEDURES VISTA Volunteer Early... has reason to believe that a Volunteer is subject to termination for any of the grounds cited in § 1210.3-1, an ACTION staff member will discuss the matter with the Volunteer. If, after the discussion...

  20. 10 CFR 851.32 - Action on variance requests.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... cited by the Chief Health, Safety and Security Officer; or (ii) Forward to the Under Secretary the... DEPARTMENT OF ENERGY WORKER SAFETY AND HEALTH PROGRAM Variances § 851.32 Action on variance requests. (a) Procedures for an approval recommendation. (1) If the Chief Health, Safety and Security Officer recommends...

  1. 14 CFR 155.3 - Applicable law.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Applicable law. 155.3 Section 155.3... RELEASE OF AIRPORT PROPERTY FROM SURPLUS PROPERTY DISPOSAL RESTRICTIONS § 155.3 Applicable law. (a... transfer to the requirements of applicable law. Based on the laws cited in this paragraph, the...

  2. The Top 100 Most-Cited Articles in Stroke Imaging: A Bibliometric Analysis.

    PubMed

    Mohammed, Mohammed F; Marais, Olivia; Qureshi, Adnan I; Bhulani, Nizar; Ferguson, David; Abu-Alola, Hossain; Nicolaou, Savvas; Khosa, Faisal

    The goal of our study was to compile a list of the top 100 most-cited articles in stroke imaging literature across all peer-reviewed scientific journals. These articles were then analyzed to identify current trends in stroke imaging research and determine the characteristics of highly-cited articles. A database of the top 100 most-cited articles was created using Scopus and Web of Science. Articles were reviewed for applicability by 2 fellowship-trained radiologists with over 10 years of combined experience in neuroimaging. The following information was collected from each article: Article Title, Scopus Citations, Year of Publication, Journal, Journal Impact Factor, Authors, Number of Institutions, Country of Origin, Study Topic, Study Design, and Sample Size. Citations for the top 100 most-cited articles ranged from 159-810, and citations per year ranged from 5.7-516.0. Most of articles were published between 1996 and 2000 (n = 43). Articles were published across 18 journals, most commonly in Stroke (n = 40). Magnetic resonance imaging was the focus in 46 articles, computed tomogrphy in 16, and functional magnetic resonance imaging in 10. The most common study topic is prognostic use of an imaging modality (n = 27). Our study helps to characterize the field and identify the characteristics of most-cited articles. Copyright © 2018 Elsevier Inc. All rights reserved.

  3. Face-off: A new identification procedure for child eyewitnesses.

    PubMed

    Price, Heather L; Fitzgerald, Ryan J

    2016-09-01

    In 2 experiments, we introduce a new "face-off" procedure for child eyewitness identifications. The new procedure, which is premised on reducing the stimulus set size, was compared with the showup and simultaneous procedures in Experiment 1 and with modified versions of the simultaneous and elimination procedures in Experiment 2. Several benefits of the face-off procedure were observed: it was significantly more diagnostic than the showup procedure; it led to significantly more correct rejections of target-absent lineups than the simultaneous procedures in both experiments, and it led to greater information gain than the modified elimination and simultaneous procedures. The face-off procedure led to consistently more conservative responding than the simultaneous procedures in both experiments. Given the commonly cited concern that children are too lenient in their decision criteria for identification tasks, the face-off procedure may offer a concrete technique to reduce children's high choosing rates. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

  4. Alarms, Chemical

    DTIC Science & Technology

    cited in applicable qualitative materiel requirements, small development requirements, technical characteristics, and other requirements and documentation that pertain to automatic chemical agent alarms.

  5. Foot and ankle tendoscopies: current concepts review

    PubMed Central

    Monteagudo, Manuel; Maceira, Ernesto; Martinez de Albornoz, Pilar

    2016-01-01

    Tendoscopy is an apparently safe and reliable procedure to manage some foot and ankle disorders. The most common foot and ankle tendoscopies are: Achilles; peroneal; and posterior tibial tendon. Tendoscopy may be used as an adjacent procedure to other techniques. Caution is recommended to avoid neurovascular injuries. Predominantly level IV and V studies are found in the literature, with no level I studies still available. There are many promising and evolving endoscopic techniques for tendinopathies around the foot and ankle, but studies of higher levels of evidence are needed to strongly recommend these procedures. Cite this article: EFORT Open Rev 2016;1:440-447. DOI: 10.1302/2058-5241.160028 PMID:28461923

  6. Microcomputers in Libraries.

    ERIC Educational Resources Information Center

    Ertel, Monica M.

    1984-01-01

    This discussion of current microcomputer technologies available to libraries focuses on software applications in four major classifications: communications (online database searching); word processing; administration; and database management systems. Specific examples of library applications are given and six references are cited. (EJS)

  7. The HTS barcode checker pipeline, a tool for automated detection of illegally traded species from high-throughput sequencing data.

    PubMed

    Lammers, Youri; Peelen, Tamara; Vos, Rutger A; Gravendeel, Barbara

    2014-02-06

    Mixtures of internationally traded organic substances can contain parts of species protected by the Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES). These mixtures often raise the suspicion of border control and customs offices, which can lead to confiscation, for example in the case of Traditional Chinese medicines (TCMs). High-throughput sequencing of DNA barcoding markers obtained from such samples provides insight into species constituents of mixtures, but manual cross-referencing of results against the CITES appendices is labor intensive. Matching DNA barcodes against NCBI GenBank using BLAST may yield misleading results both as false positives, due to incorrectly annotated sequences, and false negatives, due to spurious taxonomic re-assignment. Incongruence between the taxonomies of CITES and NCBI GenBank can result in erroneous estimates of illegal trade. The HTS barcode checker pipeline is an application for automated processing of sets of 'next generation' barcode sequences to determine whether these contain DNA barcodes obtained from species listed on the CITES appendices. This analytical pipeline builds upon and extends existing open-source applications for BLAST matching against the NCBI GenBank reference database and for taxonomic name reconciliation. In a single operation, reads are converted into taxonomic identifications matched with names on the CITES appendices. By inclusion of a blacklist and additional names databases, the HTS barcode checker pipeline prevents false positives and resolves taxonomic heterogeneity. The HTS barcode checker pipeline can detect and correctly identify DNA barcodes of CITES-protected species from reads obtained from TCM samples in just a few minutes. The pipeline facilitates and improves molecular monitoring of trade in endangered species, and can aid in safeguarding these species from extinction in the wild. The HTS barcode checker pipeline is available at https://github.com/naturalis/HTS-barcode-checker.

  8. The HTS barcode checker pipeline, a tool for automated detection of illegally traded species from high-throughput sequencing data

    PubMed Central

    2014-01-01

    Background Mixtures of internationally traded organic substances can contain parts of species protected by the Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES). These mixtures often raise the suspicion of border control and customs offices, which can lead to confiscation, for example in the case of Traditional Chinese medicines (TCMs). High-throughput sequencing of DNA barcoding markers obtained from such samples provides insight into species constituents of mixtures, but manual cross-referencing of results against the CITES appendices is labor intensive. Matching DNA barcodes against NCBI GenBank using BLAST may yield misleading results both as false positives, due to incorrectly annotated sequences, and false negatives, due to spurious taxonomic re-assignment. Incongruence between the taxonomies of CITES and NCBI GenBank can result in erroneous estimates of illegal trade. Results The HTS barcode checker pipeline is an application for automated processing of sets of 'next generation’ barcode sequences to determine whether these contain DNA barcodes obtained from species listed on the CITES appendices. This analytical pipeline builds upon and extends existing open-source applications for BLAST matching against the NCBI GenBank reference database and for taxonomic name reconciliation. In a single operation, reads are converted into taxonomic identifications matched with names on the CITES appendices. By inclusion of a blacklist and additional names databases, the HTS barcode checker pipeline prevents false positives and resolves taxonomic heterogeneity. Conclusions The HTS barcode checker pipeline can detect and correctly identify DNA barcodes of CITES-protected species from reads obtained from TCM samples in just a few minutes. The pipeline facilitates and improves molecular monitoring of trade in endangered species, and can aid in safeguarding these species from extinction in the wild. The HTS barcode checker pipeline is available at https://github.com/naturalis/HTS-barcode-checker. PMID:24502833

  9. A Big Data Analytics Methodology Program in the Health Sector

    ERIC Educational Resources Information Center

    Lawler, James; Joseph, Anthony; Howell-Barber, H.

    2016-01-01

    The benefits of Big Data Analytics are cited frequently in the literature. However, the difficulties of implementing Big Data Analytics can limit the number of organizational projects. In this study, the authors evaluate business, procedural and technical factors in the implementation of Big Data Analytics, applying a methodology program. Focusing…

  10. Special Education in America: Its Legal and Governmental Foundations.

    ERIC Educational Resources Information Center

    Ballard, Joseph, Ed.; And Others

    The text presents six chapters on the legal and governmental bases of special education. In the Introduction, F. Weintraub and J. Ballard cite the legislative and litigative history of P.L. 94-142, the Education for All Handicapped Children Act, and briefly address information sources on such policy issues as procedural safeguards, underserved…

  11. 32 CFR 290.4 - Policy.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 2 2010-07-01 2010-07-01 false Policy. 290.4 Section 290.4 National Defense... PROGRAM DEFENSE CONTRACT AUDIT AGENCY (DCAA) FREEDOM OF INFORMATION ACT PROGRAM § 290.4 Policy. Agency policy and procedures are those cited in DoD 5400.7-R. In addition, DCAA will: (a) Promote public trust...

  12. Living on a Cotton Farm: Mexican American Life in Texas.

    ERIC Educational Resources Information Center

    Black, Mary S.

    This packet of six lesson plans highlights Mexican-American life on a Texas cotton farm in the early 20th century. Each lesson provides a lesson overview; states educational objectives; cites materials needed; details the procedure for classroom implementation; offers a closure activity; and suggests an extension activity. The packet is divided…

  13. Pre-Service Teachers' Humanistic vs. Custodial Beliefs: Before and After the Student Teaching Experience

    ERIC Educational Resources Information Center

    Schramm-Possinger, Megan

    2016-01-01

    The student teaching experience is cited as one of the most critical facets of teachers' professional development. However, teachers' beliefs about pedagogical practices and disciplinary procedures, as well as their perceptions of students, also influence the approaches they use in the classroom. This study uses a humanistic and custodial…

  14. 32 CFR 584.6 - Procedures governing nonactive duty or discharged personnel.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... under his or her control. (See AR 140-1, para 1-6.) (iii) Commander, RCPAC for nonunit members assigned to Control Groups of the Ready Reserve, Standby Reserve, and Retired Reserve. (3) The officials cited... delivery. (ii) That the military department does not control the personal affairs of nonactive duty...

  15. 32 CFR 584.6 - Procedures governing nonactive duty or discharged personnel.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... under his or her control. (See AR 140-1, para 1-6.) (iii) Commander, RCPAC for nonunit members assigned to Control Groups of the Ready Reserve, Standby Reserve, and Retired Reserve. (3) The officials cited... delivery. (ii) That the military department does not control the personal affairs of nonactive duty...

  16. 32 CFR 584.6 - Procedures governing nonactive duty or discharged personnel.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... under his or her control. (See AR 140-1, para 1-6.) (iii) Commander, RCPAC for nonunit members assigned to Control Groups of the Ready Reserve, Standby Reserve, and Retired Reserve. (3) The officials cited... delivery. (ii) That the military department does not control the personal affairs of nonactive duty...

  17. The Paper Airplane Challenge: A Market Economy Simulation. Lesson Plan.

    ERIC Educational Resources Information Center

    Owens, Kimberly

    This lesson plan features a classroom simulation that helps students understand the characteristics of a market economic system. The lesson plan states a purpose; cites student objectives; suggests a time duration; lists materials needed; and details a step-by-step teaching procedure. The "Paper Airplane Challenge" handout is attached. (BT)

  18. Misrepresentation of publications by radiology residency applicants.

    PubMed

    Baker, D R; Jackson, V P

    2000-09-01

    The authors' purpose was to determine the extent of misrepresentation of research publications by radiology resident applicants. The authors reviewed 379 consecutive applications, including curricula vitae, for a radiology residency program in 1996. All reported publications and "in-press" articles were checked by means of a MEDLINE search. Of the 379 applicants, 108 were from medical schools in the United States, and 271 were from international medical schools. Seventy-three applicants listed articles published or in press on their applications (24 U.S., 49 international applicants). Of 286 separate citations in the applications, 105 were found with the MEDLINE search, and 181 were not found. Of the latter, 168 cited journals were not indexed in MEDLINE or the applicants did not include sufficient information to verify their existence. Thirteen citations (from eight applicants; three U.S., five international) were not found even though they cited journals indexed by MEDLINE. Of all applicants reporting publications, 11% likely misrepresented them on their applications. A large percentage of citations, however, could not be verified because of insufficient information in the citation or claimed publication in a journal not available on MEDLINE. Radiology residency program directors should be aware of this uncommon, but important, problem.

  19. 75 FR 13135 - Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-18

    ...). Grant applications for the Medical Liability and Safety Demonstration Projects (R18) applications are to... disclosure under the above-cited statutes. SEP Meeting on: Medical Liability and Safety Demonstration.... Bonnie Campbell, Committee Management Officer, Office of Extramural Research, Education and Priority...

  20. 14 CFR 302.303 - Contents of applications.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... is governed by a bilateral agreement or by principles of comity and reciprocity. Applications by... similar to that requested. If so, the application shall state whether the fact of reciprocity has been established by the Department and cite the pertinent finding. If the fact of reciprocity has not been...

  1. 14 CFR 302.303 - Contents of applications.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... is governed by a bilateral agreement or by principles of comity and reciprocity. Applications by... similar to that requested. If so, the application shall state whether the fact of reciprocity has been established by the Department and cite the pertinent finding. If the fact of reciprocity has not been...

  2. 14 CFR 302.303 - Contents of applications.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... is governed by a bilateral agreement or by principles of comity and reciprocity. Applications by... similar to that requested. If so, the application shall state whether the fact of reciprocity has been established by the Department and cite the pertinent finding. If the fact of reciprocity has not been...

  3. 14 CFR 302.303 - Contents of applications.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... is governed by a bilateral agreement or by principles of comity and reciprocity. Applications by... similar to that requested. If so, the application shall state whether the fact of reciprocity has been established by the Department and cite the pertinent finding. If the fact of reciprocity has not been...

  4. 14 CFR 302.303 - Contents of applications.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... is governed by a bilateral agreement or by principles of comity and reciprocity. Applications by... similar to that requested. If so, the application shall state whether the fact of reciprocity has been established by the Department and cite the pertinent finding. If the fact of reciprocity has not been...

  5. International Conferences and Young Scientists Schools on Computational Information Technologies for Environmental Sciences (CITES) as a professional growth instrument

    NASA Astrophysics Data System (ADS)

    Gordov, E. P.; Lykosov, V. N.; Genina, E. Yu; Gordova, Yu E.

    2017-11-01

    The paper describes a regular events CITES consisting of young scientists school and international conference as a tool for training and professional growth. The events address the most pressing issues of application of information-computational technologies in environmental sciences and young scientists’ training, diminishing a gap between university graduates’ skill and concurrent challenges. The viability of the approach to the CITES organization is proved by the fact that single event organized in 2001 turned into a series, quite a few young participants successfully defended their PhD thesis and a number of researchers became Doctors of Science during these years. Young researchers from Russia and foreign countries show undiminishing interest to these events.

  6. Proposed design procedure for transmission shafting under fatigue loading

    NASA Technical Reports Server (NTRS)

    Loewenthal, S. H.

    1978-01-01

    The B106 American National Standards Committee is currently preparing a new standard for the design of transmission shafting. A design procedure, proposed for use in the new standard, for computing the diameter of rotating solid steel shafts under combined cyclic bending and steady torsion is presented. The formula is based on an elliptical variation of endurance strength with torque exhibited by combined stress fatigue data. Fatigue factors are cited to correct specimen bending endurance strength data for use in the shaft formula. A design example illustrates how the method is to be applied.

  7. Further details on the applicability of Thellier paleointensity method: The effect of magnitude of laboratory field

    NASA Astrophysics Data System (ADS)

    Morales, Juan; Goguitchaichvili, Avto; Alva-Valdivia, Luis M.; Urrutia-Fucugauchi, Jaime

    2006-06-01

    Twenty years after Tanaka and Kono's pioneering contribution (Tanaka and Kono, 1984), we give some new details on the effect of applied field strength during Thellier paleointensity experiments. Special attention is paid to the relation of magnitude of laboratory field and Coe's quality factors (Coe et al., 1978). Full thermoremanent magnetizations were imparted on natural samples containing low-Ti titanomagnetites of pseudo-single domain structure in a 40-μT magnetic field from 600 °C to room temperature. The samples were subjected to the routine Thellier procedure using a wide range of applied laboratory fields. Results indicate that values of laboratory fields may be accurately reproduced within 2% of standard error. The quality factors, however, decrease when the magnitude of 'ancient' field does not match to applied laboratory fields. To cite this article: J. Morales et al., C. R. Geoscience 338 (2006).

  8. Radioelectronics and space exploration

    NASA Astrophysics Data System (ADS)

    Sarafanov, T.; Bogoroditskiy, Y.; Milyukov, I.

    1985-03-01

    Citing the 23 years since Yuriy Gagarin's first radio transmission from outer space, the developments in radio communications and their role in mission control are summarized. Use of satellites for radio and television links with ground stations are an important part of information exchange. Construction and preventive maintenance activities by Soviet cosmonauts, use of radio technology for docking procedures and the reliability of such equipment, and the growing role of computer technology in space vehicles with human crews and pilotless craft are discussed. Automatic interplanetary vehicles that have landed on the moon, Mars and Venus, as well as artificial earth satellites, are facilitating weather and communication advances. Mock space equipment using radio and computer technology is of great importance for training cosmonauts. Despite all these practical applications, optimum utilization of automated equipment has yet to be achieved, and offers further challenge to Soviet and other engineers and technicians.

  9. 75 FR 13134 - Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-18

    ...)(6). Grant applications for the Medical Liability and Safety Innovation Projects (R21) applications... disclosure under the above- cited statutes. SEP Meeting on: Medical Liability and Safety Innovation Projects..., Committee Management Officer, Office of Extramural Research, Education and Priority Populations, AHRQ, 540...

  10. The Influence of the Knowledge Base on the Development of Mnemonic Strategies.

    ERIC Educational Resources Information Center

    Ornstein, Peter A.; Naus, Mary J.

    A dominant theme in cognitive psychology is that prior knowledge in long-term memory has a strong influence on an individual's cognitive processing. Citing numerous memory studies with children, knowledge base effects are presented as part of a broader picture of memory development. Using the sort/recall procedure (asking subjects to group sets of…

  11. 49 CFR Appendix F to Part 236 - Minimum Requirements of FRA Directed Independent Third-Party Assessment of PTC System Safety...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ..., national, or international standards. (f) The reviewer shall analyze all Fault Tree Analyses (FTA), Failure... cited by the reviewer; (4) Identification of any documentation or information sought by the reviewer...) Identification of the hardware and software verification and validation procedures for the PTC system's safety...

  12. 24 CFR 50.19 - Categorical exclusions not subject to the Federal laws and authorities cited in § 50.4.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... implementation of these categories of activities and policy documents does not require environmental review, because they do not alter physical conditions in a manner or to an extent that would require review under... ENVIRONMENTAL QUALITY General Policy: Environmental Review Procedures § 50.19 Categorical exclusions not subject...

  13. 15 CFR 904.301 - Bases for permit sanctions or denials.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 15 Commerce and Foreign Trade 3 2011-01-01 2011-01-01 false Bases for permit sanctions or denials... PROCEDURES Permit Sanctions and Denials General § 904.301 Bases for permit sanctions or denials. (a) Unless... under this subpart with respect to any permit issued under the statutes cited in § 904.1(c). The bases...

  14. 75 FR 47646 - Idaho State University; Notice of Issuance of Director's Decision

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-06

    ... detector from the reactor core. In the petition Dr. Crawford states that this was cited as an Apparent... detector. The personnel roof access hatch was also addressed in Rev. 3 and Rev. 4 of the Physical Security... procedures to wear protective clothing to routinely remove the activated startup channel detector from the...

  15. 32 CFR Appendix A to Part 584 - Reference

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Certain Other Units of the Army. AR 340-18 The Army Functional Files System AR 600-240 Marriage in Oversea...-17 Release of Information and Records from Army Files. (Cited in § 584.1(f)(2).) AR 340-21 The Army... regulation. AR 11-2 Internal Control Systems AR 20-1 Inspector General Activities and Procedures AR 140-1...

  16. 32 CFR Appendix A to Part 584 - Reference

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Certain Other Units of the Army. AR 340-18 The Army Functional Files System AR 600-240 Marriage in Oversea...-17 Release of Information and Records from Army Files. (Cited in § 584.1(f)(2).) AR 340-21 The Army... regulation. AR 11-2 Internal Control Systems AR 20-1 Inspector General Activities and Procedures AR 140-1...

  17. 32 CFR Appendix A to Part 584 - Reference

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Certain Other Units of the Army. AR 340-18 The Army Functional Files System AR 600-240 Marriage in Oversea...-17 Release of Information and Records from Army Files. (Cited in § 584.1(f)(2).) AR 340-21 The Army... regulation. AR 11-2 Internal Control Systems AR 20-1 Inspector General Activities and Procedures AR 140-1...

  18. 32 CFR Appendix A to Part 584 - Reference

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Certain Other Units of the Army. AR 340-18 The Army Functional Files System AR 600-240 Marriage in Oversea...-17 Release of Information and Records from Army Files. (Cited in § 584.1(f)(2).) AR 340-21 The Army... regulation. AR 11-2 Internal Control Systems AR 20-1 Inspector General Activities and Procedures AR 140-1...

  19. Absentee Voting among Privately-Employed U.S. Citizens Living Overseas: Findings from the 1978 Post-Election Voting Survey (Form B).

    DTIC Science & Technology

    1979-06-01

    citizens who live overseas. The questions concerned absentee voting experiences in the 1978 general election, interest in the election, sources of...cast ballots in the 1978 election. The most frequently cited reason for not voting was lack of information on absentee voting procedures. (Author)

  20. Early Morning Challenge: The Potential Effects of Chronobiology on Taking the Scholastic Aptitude Test.

    ERIC Educational Resources Information Center

    Callan, Roger John

    1995-01-01

    Cites research to support the notion that the time of day in which the SAT is administered has a significant adverse impact on many students taking the test. Suggests that changes in testing procedures (making tests available via computer at any time of the day or year) will serve students. (RS)

  1. Top 100 Cited articles on Radiation Exposure in Medical Imaging: A Bibliometric Analysis.

    PubMed

    Kinnin, Jason; Hanna, Tarek N; Jutras, Marc; Hasan, Babar; Bhatia, Rick; Khosa, Faisal

    2018-03-20

    Bibliometric analyses by highest number of citations can help researchers and funding agencies in determining the most influential articles in a field. The main objective of this analysis was to identify the top 100 cited articles addressing radiation exposure from medical imaging and assess their characteristics. Relevant articles were extracted from the Scopus database after a systematic search by researchers using an iteratively defined Boolean search string. Subsequently, exclusion criteria were applied. A list of top 100 articles was prepared, and articles were ranked according to the citations they had received. No time restriction was applied. Descriptive statistics of the data were compiled. The top-cited articles were published from 1970-2013, with the most articles published in 2009 and 2010 (12 articles in each year). The citations ranged from 107-1888 with a median of 272. Manuscripts from our top-cited list originated from 20 different countries, with contributions made by 158 authors and 160 organizations. Eighty-eight percent of studies evaluated patient-related radiation exposure, 7% health care workers, and 5% both or were not specified. Thirty-two percent of studies examined adult populations, 14% pediatric, and 54% included both populations or did not specify. Seventy-two percent of studies were dedicated to Computed Tomography, 8% to radiography/fluoroscopy, 9% to interventional procedures, 4% to nuclear medicine, and 7% to a combination of 2 or more modalities. The top 100 cited articles in medical imaging related to radiation exposure are diverse, originating from many countries with numerous contributing authors. The most common topics covered involve CT and adult patients. The recent peak in the most-highly cited articles (2010) suggests that increased attention has been devoted to this field in recent years. Based on these results, it would appear that research on radiation exposure in medical imaging is poised to continue expanding. Copyright © 2018 Elsevier Inc. All rights reserved.

  2. Potential Applications and Impact of Microelectronic and Telecommunication Technology in Health Care Delivery. Final Report.

    ERIC Educational Resources Information Center

    Mandex, Inc., Vienna, VA.

    This compendium of current and recent innovative methods of health care delivery focuses on telemedicine, and educational and energy management and control applications. Each application is doumented in a project abstract describing the system and the technology employed, and citing relevant information sources and a personal or organizational…

  3. Medicinal plants used for ophthalmological problems in Navarra (Spain).

    PubMed

    Calvo, M Isabel; Cavero, Rita Yolanda

    2016-08-22

    Several plants have been found to have effective against number of ophthalmological problems in Navarra. Information was collected using semi-structured ethnobotanical interviews with 686 informants in 267 locations. In order to confirm the pharmacological application of the uses more cited by the informants, a literature review was conducted. A total of 57 pharmaceutical uses were reported, for 19 plants and 13 families, mainly represented by Asteraceae. The most frequently used parts were inflorescences, flowers, aerial parts, leaves and flowered aerial parts. The related affections fell into eleven categories: bloodshot eyes, watery eyes and wounds, improve vision, irrited eyelids, rheums and styes, tired eyes, conjunctivitis, eyewash, ocular problems in general. The most cited plants were: Chamaemelum nobile (L.) All., Santolina chamaecyparissus L. ssp. squarrosa (DC.) Nyman, Sambucus nigra L. ssp. nigra, Rosa agrestis Savi and Calendula officinalis L. None of them have been pharmacologically validated by Official International Organisms. From the therapeutic point of view, Allium sativum L., Foeniculum vulgare Mill., C. officinalis, and S. chamaecyparissus ssp. squarrosa deserve special attention, because ethnobotanical and pharmacological studies suggest that these medicinal plants are effective for ophthalmological problems. The present study constitutes a good basis for further phytochemical and pharmacological research of these four plants, which could be of interest in the design of new inexpensive, effective and safe drugs. The remaining plants are needed to be screened through standard pharmacological and clinical procedures for their activities. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  4. Raman Spectrometry.

    ERIC Educational Resources Information Center

    Gardiner, Derek J.

    1980-01-01

    Reviews mainly quantitative analytical applications in the field of Raman spectrometry. Includes references to other reviews, new and analytically untested techniques, and novel sampling and instrument designs. Cites 184 references. (CS)

  5. Medicinal Product Regulation: Portugal׳s Framework.

    PubMed

    Herdeiro, Maria Teresa; Bastos, Paulo D; Teixeira-Rodrigues, António; Roque, Fátima

    2016-09-01

    The pharmaceutical industry is one of the most tightly regulated sectors, and it is essential to know each country׳s legal framework to understand the regulation, approval, and marketing of medicinal products for human use. This article describes the main statutes and procedures governing medicinal products for human use in Portugal and the role of the country׳s National Medicines and Health Products Authority (Autoridade Nacional do Medicamento e Produtos de Saúde, I.P.; INFARMED). From the most recently available data, an update of requests and approvals concerning marketing authorizations, variations, pricing, and reimbursements is provided. Data were sourced from the INFARMED website, Infomed (database of medicinal products for human use), and periodic reports issued by national authorities. Organic laws, acts, and law decrees published in the government gazette (Diário da República) are cited and reproduced as required. In 2015 Portugal ranked fifth in the European System of Medicines Evaluation in terms of the number of completed procedures as a reference member state. Approximately 80% of all approved drug applications in Portugal in 2015 were for generic drugs, mostly pertaining to the nervous system. In Portugal, INFARMED monitors drug quality, safety profile, and efficacy in all stages of the drug life cycle, ensuring patients' safety. The Portuguese market for medicinal products for human use has been appreciably changed by the advent of generic drugs. There is an increased trend for new request applications for biological and biotechnological substances. Copyright © 2016 Elsevier HS Journals, Inc. All rights reserved.

  6. 77 FR 442 - Changes To Implement Miscellaneous Post Patent Provisions of the Leahy-Smith America Invents Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-05

    ... to Manual of Patent Examining Procedure (MPEP) Sec. 2282 (8th ed. 2001) (Rev. 8, July 2010). MPEP Sec... reexamination based on patents and publications cited in a prior reexamination request under 35 U.S.C. 302, as... prior art directed to patents or printed publications allegedly bearing on the patentability of any...

  7. 50 CFR 23.90 - What are the criteria for listing species in Appendix III?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... ENDANGERED SPECIES OF WILD FAUNA AND FLORA (CITES) Lists of Species § 23.90 What are the criteria for listing species in Appendix III? (a) Purpose. Article XVI of the Treaty sets out the procedures for amending... 50 Wildlife and Fisheries 6 2010-10-01 2010-10-01 false What are the criteria for listing species...

  8. 50 CFR 23.90 - What are the criteria for listing species in Appendix III?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... ENDANGERED SPECIES OF WILD FAUNA AND FLORA (CITES) Lists of Species § 23.90 What are the criteria for listing species in Appendix III? (a) Purpose. Article XVI of the Treaty sets out the procedures for amending... 50 Wildlife and Fisheries 9 2013-10-01 2013-10-01 false What are the criteria for listing species...

  9. 50 CFR 23.90 - What are the criteria for listing species in Appendix III?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... ENDANGERED SPECIES OF WILD FAUNA AND FLORA (CITES) Lists of Species § 23.90 What are the criteria for listing species in Appendix III? (a) Purpose. Article XVI of the Treaty sets out the procedures for amending... 50 Wildlife and Fisheries 9 2012-10-01 2012-10-01 false What are the criteria for listing species...

  10. 50 CFR 23.90 - What are the criteria for listing species in Appendix III?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... ENDANGERED SPECIES OF WILD FAUNA AND FLORA (CITES) Lists of Species § 23.90 What are the criteria for listing species in Appendix III? (a) Purpose. Article XVI of the Treaty sets out the procedures for amending... 50 Wildlife and Fisheries 8 2011-10-01 2011-10-01 false What are the criteria for listing species...

  11. 32 CFR 623.4 - Accounting procedures.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... or O) indicating which loan of the day is first; e.g., A-first, B-second, etc. 51 “M”. 52-53 “G4” for... commercial bills of lading (CBL). Freight charges will be paid by the borrower. The CBL will cite proper project codes. NOTE: In emergencies where use of CBL would delay shipment, government bills of lading (GBL...

  12. 32 CFR 623.4 - Accounting procedures.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... or O) indicating which loan of the day is first; e.g., A-first, B-second, etc. 51 “M”. 52-53 “G4” for... commercial bills of lading (CBL). Freight charges will be paid by the borrower. The CBL will cite proper project codes. NOTE: In emergencies where use of CBL would delay shipment, government bills of lading (GBL...

  13. Remarques critiques a propos de l'enquete international sur la litteratie (Critical Remarks Regarding the International Adult Literacy Survey).

    ERIC Educational Resources Information Center

    Manesse, Daniele

    2000-01-01

    States that French authorities refused to make International Adult Literacy Survey results public, citing methodological flaws, the need for better procedural precautions, and a more adequate notion of literacy. Presents a synthesis of the counter investigations demanded by French authorities that justify their doubts on the IALS definitions and…

  14. NASA patent abstracts bibliography: A continuing bibliography. Section 1: Abstracts (supplement 06)

    NASA Technical Reports Server (NTRS)

    1975-01-01

    Patents and applications for patent introduced into the NASA scientific and technical information system are cited. Each entry consists of a citation, an abstract, and a key illustration selected from the patent or application for patent. The patent and application for patent citations are indexed according to subject, inventor, source, number, and accession number.

  15. Laminates and reinforced metals

    NASA Technical Reports Server (NTRS)

    Chamis, C. C.

    1980-01-01

    A selective review is presented of the state of the art of metallic laminates and fiber reinforced metals called metallic matrix laminates (MMLs). Design and analysis procedures that are used for, and typical structural components that have been made from MMLs are emphasized. Selected MMLs, constituent materials, typical material properties and fabrication procedures are briefly described, including hybrids and superhybrids. Advantages, disadvantages, and special considerations required during design, analysis, and fabrication of MMLs are examined. Tabular and graphical data are included to illustrate key aspects of MMLs. Appropriate references are cited to provide a selective bibliography of a rapidly expanding and very promising research and development field.

  16. Standards-based curation of a decade-old digital repository dataset of molecular information.

    PubMed

    Harvey, Matthew J; Mason, Nicholas J; McLean, Andrew; Murray-Rust, Peter; Rzepa, Henry S; Stewart, James J P

    2015-01-01

    The desirable curation of 158,122 molecular geometries derived from the NCI set of reference molecules together with associated properties computed using the MOPAC semi-empirical quantum mechanical method and originally deposited in 2005 into the Cambridge DSpace repository as a data collection is reported. The procedures involved in the curation included annotation of the original data using new MOPAC methods, updating the syntax of the CML documents used to express the data to ensure schema conformance and adding new metadata describing the entries together with a XML schema transformation to map the metadata schema to that used by the DataCite organisation. We have adopted a granularity model in which a DataCite persistent identifier (DOI) is created for each individual molecule to enable data discovery and data metrics at this level using DataCite tools. We recommend that the future research data management (RDM) of the scientific and chemical data components associated with journal articles (the "supporting information") should be conducted in a manner that facilitates automatic periodic curation. Graphical abstractStandards and metadata-based curation of a decade-old digital repository dataset of molecular information.

  17. 48 CFR 22.804-2 - Construction.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Construction. 22.804-2... are required to meet (1) the contract terms and conditions citing affirmative action requirements applicable to covered geographical areas or projects and (2) applicable requirements of 41 CFR 60-1 and 60-4...

  18. 13 CFR 125.5 - Certificate of Competency Program.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... the type of product being procured or the specific contract at issue. (iv) A non-manufacturer making... application. (1) The COC review process is not limited to the areas of nonresponsibility cited by the contracting officer. SBA may, at its discretion, independently evaluate the COC applicant for all elements of...

  19. Award for Distinguished Scientific Applications of Psychology: Nancy E. Adler

    ERIC Educational Resources Information Center

    American Psychologist, 2009

    2009-01-01

    Nancy E. Adler, winner of the Award for Distinguished Scientific Applications of Psychology, is cited for her research on reproductive health examining adolescent decision making with regard to contraception, conscious and preconscious motivations for pregnancy, and perception of risk for sexually transmitted diseases, and for her groundbreaking…

  20. Applications of Jungian Type Theory to Counselor Education.

    ERIC Educational Resources Information Center

    Dilley, Josiah S.

    1987-01-01

    Describes Carl Jung's theory of psychological type and the Myers-Briggs Type Indicator (MBTI), an instrument to assess Jungian type. Cites sources of information on the research and application of the theory and the MBTI. Explores how knowledge of type theory can be useful to counselor educators. (Author)

  1. Recycling research progress at the Forest Products Laboratory.

    Treesearch

    1995-01-01

    This document summarizes accomplishments of USDA Forest Service researchers in the area of recycling. Specifically, it describes work in economic assessment, paper recycling, recycled housing and industrial applications of recycled materials, other recycling applications, and technology transfer. The literature list includes the references cited in the text and...

  2. Magnetic suspension options for spacecraft inertia-wheel applications

    NASA Technical Reports Server (NTRS)

    Downer, J. R.

    1984-01-01

    Design criteria for spacecraft inertia-wheel suspensions are listed. The advantages of magnetic suspensions over other suspension types for spacecraft inertia-wheel applications are cited along with the functions performed by magnetic suspension. The common designs for magnetic suspensions are enumerated. Materials selection of permanent magnets and core materials is considered.

  3. Simultaneous determination of some cholesterol-lowering drugs in their binary mixture by novel spectrophotometric methods

    NASA Astrophysics Data System (ADS)

    Lotfy, Hayam Mahmoud; Hegazy, Maha Abdel Monem

    2013-09-01

    Four simple, specific, accurate and precise spectrophotometric methods manipulating ratio spectra were developed and validated for simultaneous determination of simvastatin (SM) and ezetimibe (EZ) namely; extended ratio subtraction (EXRSM), simultaneous ratio subtraction (SRSM), ratio difference (RDSM) and absorption factor (AFM). The proposed spectrophotometric procedures do not require any preliminary separation step. The accuracy, precision and linearity ranges of the proposed methods were determined, and the methods were validated and the specificity was assessed by analyzing synthetic mixtures containing the cited drugs. The four methods were applied for the determination of the cited drugs in tablets and the obtained results were statistically compared with each other and with those of a reported HPLC method. The comparison showed that there is no significant difference between the proposed methods and the reported method regarding both accuracy and precision.

  4. 77 FR 25192 - Wild Bird Conservation Act; Receipt of Application for Approval of a Cooperative Breeding Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-27

    ... Conservation Act of 1992 (WBCA). DATES: Written data, comments, or requests for a copy of this application must... to the Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES). Under...-FF09A30000] Wild Bird Conservation Act; Receipt of Application for Approval of a Cooperative Breeding Program...

  5. Application of remote sensing to hydrological problems and floods

    NASA Technical Reports Server (NTRS)

    Parada, N. D. J. (Principal Investigator); Novo, E. M. L. M.

    1983-01-01

    The main applications of remote sensors to hydrology are identified as well as the principal spectral bands and their advantages and disadvantages. Some examples of LANDSAT data applications to flooding-risk evaluation are cited. Because hydrology studies the amount of moisture and water involved in each phase of hydrological cycle, remote sensing must be emphasized as a technique for hydrological data acquisition.

  6. Gold Medal Award for Life Achievement in the Application of Psychology: Edwin A. Fleishman

    ERIC Educational Resources Information Center

    American Psychologist, 2004

    2004-01-01

    The 2004 Gold Medal Award for Life Achievement in the Application of Psychology was awarded to Edwin A. Fleishman, for his significant contributions to the science and applications of psychology, which he has sustained over his remarkable career. He is cited for his research, which has had a profound influence on our understanding of human…

  7. Hiring and Retention: Key Factors in Increasing Gender Diversity in the Geosciences

    NASA Astrophysics Data System (ADS)

    Holmes, M.; O'Connell, S.; Frey, C.

    2004-12-01

    Graduation and hiring data of geoscientists over the last ten years indicate that the largest leak in the academic pipeline for women geoscientists is at hiring into tenure-track positions. Anecdotal explanations for this leak generally cite a lack of females in the applicant pool, but women in tenure-track positions anecdotally cite a lack of family-friendly practices by academic departments. Both ideas are currently being tested via surveys of geoscience departments. Is there a way to attract more women to the field to increase the applicant pool? Results of focus groups of geoscientists indicate that both men and women are attracted into the field of geosciences by the same types of events: over one-third became a geoscientist by randomly walking into an undergraduate class and finding themselves captivated by the topic and/or a dynamic instructor. The subject matter itself attracts another one-fourth, and family members encourage another one-fifth of geoscientists to initially enter the field. Slightly more women cite the first attractor of undergraduate class, but the principal draw for our future workforce, male and female, is good instruction of freshman courses. Retention of women in academia is another key issue. The proportion that considers leaving after working towards one or more degrees is highly skewed by gender: one-half of female and only one-third of male geoscientists considered leaving the field at some time in their career. The reasons for considering leaving also differ by gender. Males cite financial issues, including an uncertain job market. Females cite two principal reasons for considering leaving: family issues and difficulties with a graduate advisor. Strategies currently exist for "family issues", including stop-the-clock (of tenure for family needs), assignment shift, on-campus daycare facilities, and unflinching administrative support for such practices. Graduate advising is a learnable skill, and more attention needs to be paid to this critical issue for female retention in the geosciences.

  8. Screening procedure to evaluate effects of air pollution on Eastern Region wildernesses cited as Class I air quality areas.

    Treesearch

    Mary Beth Adams; Dale S. Nichols; Anthony C. Federer; Keith F. Jensen; Harry Parrott

    1991-01-01

    The USDA Forest Service's Eastern Region manages eight wilderness areas that have been designated as Class I air quality areas by the Federal Clean Air Act. As part of this legislation, Federal land managers are required to consult with air pollution regulators on the potential impacts of proposed air pollution emissions--including phytotoxic gases and acidic...

  9. 50 CFR 23.89 - What are the criteria for listing species in Appendix I or II?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... ENDANGERED SPECIES OF WILD FAUNA AND FLORA (CITES) Lists of Species § 23.89 What are the criteria for listing species in Appendix I or II? (a) Purpose. Article XV of the Treaty sets out the procedures for amending... 50 Wildlife and Fisheries 8 2011-10-01 2011-10-01 false What are the criteria for listing species...

  10. 50 CFR 23.89 - What are the criteria for listing species in Appendix I or II?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... ENDANGERED SPECIES OF WILD FAUNA AND FLORA (CITES) Lists of Species § 23.89 What are the criteria for listing species in Appendix I or II? (a) Purpose. Article XV of the Treaty sets out the procedures for amending... 50 Wildlife and Fisheries 9 2013-10-01 2013-10-01 false What are the criteria for listing species...

  11. 50 CFR 23.89 - What are the criteria for listing species in Appendix I or II?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... ENDANGERED SPECIES OF WILD FAUNA AND FLORA (CITES) Lists of Species § 23.89 What are the criteria for listing species in Appendix I or II? (a) Purpose. Article XV of the Treaty sets out the procedures for amending... 50 Wildlife and Fisheries 9 2012-10-01 2012-10-01 false What are the criteria for listing species...

  12. 50 CFR 23.89 - What are the criteria for listing species in Appendix I or II?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... ENDANGERED SPECIES OF WILD FAUNA AND FLORA (CITES) Lists of Species § 23.89 What are the criteria for listing species in Appendix I or II? (a) Purpose. Article XV of the Treaty sets out the procedures for amending... 50 Wildlife and Fisheries 6 2010-10-01 2010-10-01 false What are the criteria for listing species...

  13. Chemical Insight Into The Origin of Red and Blue Photoluminescence Arising From Freestanding Silicon Nanocrystals

    PubMed Central

    Dasog, Mita; Yang, Zhenyu; Regli, Sarah; Atkins, Tonya M.; Faramus, Angelique; Singh, Mani P.; Muthuswamy, Elayaraja; Kauzlarich, Susan M.; Tilley, Richard D.; Veinot, Jonathan G. C.

    2013-01-01

    Silicon nanocrystals (Si NCs) are attractive functional materials. They are compatible with standard electronics and communications platforms as well being biocompatible. Numerous methods have been developed to realize size-controlled Si NC synthesis. While these procedures produce Si NCs that appear identical, their optical responses can differ dramatically. Si NCs prepared using high-temperature methods routinely exhibit photoluminescence agreeing with the effective mass approximation (EMA), while those prepared via solution methods exhibit blue emission that is somewhat independent of particle size. Despite many proposals, a definitive explanation for this difference has been elusive for no less than a decade. This apparent dichotomy brings into question our understanding of Si NC properties and potentially limits the scope of their application. The present contribution takes a substantial step forward toward identifying the origin of the blue emission that is not expected based upon EMA predictions. It describes a detailed comparison of Si NCs obtained from three of the most widely cited procedures as well as the conversion of red-emitting Si NCs to blue-emitters upon exposure to nitrogen containing reagents. Analysis of the evidence is consistent with the hypothesis that the presence of trace nitrogen and oxygen even at the ppm level in Si NCs gives rise to the blue emission. PMID:23394574

  14. Chemical insight into the origin of red and blue photoluminescence arising from freestanding silicon nanocrystals.

    PubMed

    Dasog, Mita; Yang, Zhenyu; Regli, Sarah; Atkins, Tonya M; Faramus, Angelique; Singh, Mani P; Muthuswamy, Elayaraja; Kauzlarich, Susan M; Tilley, Richard D; Veinot, Jonathan G C

    2013-03-26

    Silicon nanocrystals (Si NCs) are attractive functional materials. They are compatible with standard electronics and communications platforms and are biocompatible. Numerous methods have been developed to realize size-controlled Si NC synthesis. While these procedures produce Si NCs that appear identical, their optical responses can differ dramatically. Si NCs prepared using high-temperature methods routinely exhibit photoluminescence agreeing with the effective mass approximation (EMA), while those prepared via solution methods exhibit blue emission that is somewhat independent of particle size. Despite many proposals, a definitive explanation for this difference has been elusive for no less than a decade. This apparent dichotomy brings into question our understanding of Si NC properties and potentially limits the scope of their application. The present contribution takes a substantial step forward toward identifying the origin of the blue emission that is not expected based upon EMA predictions. It describes a detailed comparison of Si NCs obtained from three of the most widely cited procedures as well as the conversion of red-emitting Si NCs to blue emitters upon exposure to nitrogen-containing reagents. Analysis of the evidence is consistent with the hypothesis that the presence of trace nitrogen and oxygen even at the parts per million level in Si NCs gives rise to the blue emission.

  15. Synthetic Vision Enhanced Surface Operations and Flight Procedures Rehearsal Tool

    NASA Technical Reports Server (NTRS)

    Arthur, Jarvis J., III; Prinzel, Lawrence J., III; Williams, Steven P.; Kramer, Lynda J.

    2006-01-01

    Limited visibility has been cited as predominant causal factor for both Controlled-Flight-Into-Terrain (CFIT) and runway incursion accidents. NASA is conducting research and development of Synthetic Vision Systems (SVS) technologies which may potentially mitigate low visibility conditions as a causal factor to these accidents while replicating the operational benefits of clear day flight operations, regardless of the actual outside visibility condition. Two experimental evaluation studies were performed to determine the efficacy of two concepts: 1) head-worn display application of SVS technology to enhance transport aircraft surface operations, and 2) three-dimensional SVS electronic flight bag display concept for flight plan preview, mission rehearsal and controller-pilot data link communications interface of flight procedures. In the surface operation study, pilots evaluated two display devices and four display modes during taxi under unlimited and CAT II visibility conditions. In the mission rehearsal study, pilots flew approaches and departures in an operationally-challenged airport environment, including CFIT scenarios. Performance using the SVS concepts was compared to traditional baseline displays with paper charts only or EFB information. In general, the studies evince the significant situation awareness and enhanced operational capabilities afforded from these advanced SVS display concepts. The experimental results and conclusions from these studies are discussed along with future directions.

  16. Costs and benefits

    NASA Technical Reports Server (NTRS)

    1975-01-01

    Two models of cost benefit analysis are illustrated and the application of these models to assessing the economic scope of space applications programs was discussed. Four major areas cited as improvable through space derived information - food supply and distribution, energy sources, mineral reserves, and communication and navigation were - discussed. Specific illustrations are given for agriculture and maritime traffic.

  17. NASA patent abstracts bibliography: A continuing bibliography. Section 1: Abstracts (supplement 19)

    NASA Technical Reports Server (NTRS)

    1981-01-01

    Abstracts are cited for 130 patents and patent applications introduced into the NASA scientific and technical information system during the period of January 1981 through July 1981. Each entry consists of a citation, an abstract, and in most cases, a key illustration selected from the patent or application for patent.

  18. NASA patent abstracts bibliography. A continuing bibliography (supplement 22). Section 1: Abstracts

    NASA Technical Reports Server (NTRS)

    1983-01-01

    Abstracts are cited for 234 patents and patent applications introduced into the NASA scientific and technical information system during the period July 1982 through December 1982. Each entry consists of a citation, an abstract, and in most cases, a key illustration selected from the patent or patent application.

  19. NASA patent abstracts bibliography: A continuing bibliography. Section 1: Abstracts (supplement 15)

    NASA Technical Reports Server (NTRS)

    1979-01-01

    Abstracts are cited for 240 patents and applications for patents introduced into the NASA scientific system during the period of January 1979 through June 1979. Each entry consists of a citation, an abstract, and in most cases, a key illustration selected from the patent or application for patent.

  20. NASA patent abstracts bibliography: A continuing bibliography. Section 1: Abstracts (supplement 20)

    NASA Technical Reports Server (NTRS)

    1982-01-01

    Abstracts are cited for 165 patents and patent applications introduced into the NASA scientific and technical information system during the period July 1981 through December 1981. Each entry consists of a citation, an abstract, and in most cases, a key illustration selected from the patent or patent application.

  1. NASA patent abstracts bibliography: A continuing bibliography. Section 1: Abstracts (supplement 17)

    NASA Technical Reports Server (NTRS)

    1980-01-01

    Abstracts are cited for 150 patents and applications for patents introduced into the NASA scientific and technical information system during the period January 1980 through June 1980. Each entry consists of a citation, an abstract, and in most cases, a key illustration selected from the patent or application for patent.

  2. NASA Patent Abstracts bibliography: A continuing bibliography. Section 1: Abstracts (supplement 21) Abstracts

    NASA Technical Reports Server (NTRS)

    1982-01-01

    Abstracts are cited for 87 patents and applications introduced into the NASA scientific and technical information system during the period of January 1982 through June 1982. Each entry consists of a citation, an abstract, and in mose cases, a key illustration selected from the patent or patent application.

  3. NASA patent abstracts bibliography: A continuing bibliography. Section 1: Abstracts (supplement 16)

    NASA Technical Reports Server (NTRS)

    1980-01-01

    Abstracts are cited for 138 patents and patent applications introduced into the NASA scientific and technical information system during the period July 1979 through December 1979. Each entry cib consists of a citation, an abstract, and in most cases, a key illustration selected from the patent or patent application.

  4. NASA patent abstracts bibliography: A continuing bibliography. Section 1: Abstracts (supplement 14)

    NASA Technical Reports Server (NTRS)

    1979-01-01

    Abstracts are cited for 213 patents and applications for patent introduced into the NASA scientific and technical information system during the period of July 1978 through December 1978. Each entry consists of a citation, an abstract, and in most cases, a key illustration selected from the patent or application for patent.

  5. NASA patent abstracts bibliography: A continuing bibliography. Section 1: Abstracts (supplement 23)

    NASA Technical Reports Server (NTRS)

    1983-01-01

    Abstracts are cited for 129 patents and patent applications introduced into the NASA scientific and technical information system during the period January 1983 through June 1983. Each entry consists of a citation, an abstract, and in most cases, a key illustration selected from the patent or patent application.

  6. NASA patent abstracts bibliography: A continuing bibliography. Section 1: Abstracts (supplement 18)

    NASA Technical Reports Server (NTRS)

    1981-01-01

    Abstracts are cited for 120 patents and patent applications for patents introduced into the NASA scientific system during the period of July 1980 through December 1980. Each entry consists of a citation, an abstract, and in most cases, a key illustration selected from the patent or application for patent.

  7. Clinical Application of Electrocardiography.

    ERIC Educational Resources Information Center

    Brammell, H. L.; Orr, William

    The scalar electrocardiogram (ECG) is one of the most important and commonly used clinical tools in medicine. A detailed description of the recordings of cardiac electrical activity made by the ECG is presented, and the vast numbers of uses made with the data provided by this diagnostic tool are cited. Clinical applications of the ECG are listed.…

  8. Numerical modelling techniques of soft soil improvement via stone columns: A brief review

    NASA Astrophysics Data System (ADS)

    Zukri, Azhani; Nazir, Ramli

    2018-04-01

    There are a number of numerical studies on stone column systems in the literature. Most of the studies found were involved with two-dimensional analysis of the stone column behaviour, while only a few studies used three-dimensional analysis. The most popular software utilised in those studies was Plaxis 2D and 3D. Other types of software that used for numerical analysis are DIANA, EXAMINE, ZSoil, ABAQUS, ANSYS, NISA, GEOSTUDIO, CRISP, TOCHNOG, CESAR, GEOFEM (2D & 3D), FLAC, and FLAC 3. This paper will review the methodological approaches to model stone column numerically, both in two-dimensional and three-dimensional analyses. The numerical techniques and suitable constitutive model used in the studies will also be discussed. In addition, the validation methods conducted were to verify the numerical analysis conducted will be presented. This review paper also serves as a guide for junior engineers through the applicable procedures and considerations when constructing and running a two or three-dimensional numerical analysis while also citing numerous relevant references.

  9. Percutaneous triplanar femoral osteotomy correction for developmental coxa vara: a new technique.

    PubMed

    Sabharwal, Sanjeev; Mittal, Rahul; Cox, Garrick

    2005-01-01

    Developmental coxa vara (DCV) is a well-known pediatric hip disorder that is associated with triplanar deformity of the proximal femur. Several techniques of proximal femur osteotomies have being cited in the literature, with variable outcomes. Recently, the authors have used a percutaneous technique with application of a low-profile Ilizarov external fixator for acute opening wedge correction of the femoral deformity associated with DCV. Five children (six affected hips) underwent the above procedure at an average age of 8 + 4 years. The average improvement in Hilgenreiner's epiphyseal angle was from 74 degrees before surgery to 33 degrees after surgery, the neck-shaft angle improved from 86 degrees to 137 degrees, and the articulo-trochanteric distance improved from -6 mm to +11 mm. Latest follow-up at a mean of 2.1 years after surgery showed satisfactory healing with no significant loss of correction in any case. This percutaneous technique offers several advantages over currently available methods for surgical correction of DCV.

  10. Exploring the Use of Electroencephalography to Gather Objective Evidence of Cognitive Processing During Problem Solving

    NASA Astrophysics Data System (ADS)

    Delahunty, Thomas; Seery, Niall; Lynch, Raymond

    2018-04-01

    Currently, there is significant interest being directed towards the development of STEM education to meet economic and societal demands. While economic concerns can be a powerful driving force in advancing the STEM agenda, care must be taken that such economic imperative does not promote research approaches that overemphasize pragmatic application at the expense of augmenting the fundamental knowledge base of the discipline. This can be seen in the predominance of studies investigating problem solving approaches and procedures, while neglecting representational and conceptual processes, within the literature. Complementing concerns about STEM graduates' problem solving capabilities, raised within the pertinent literature, this paper discusses a novel methodological approach aimed at investigating the cognitive elements of problem conceptualization. The intention is to demonstrate a novel method of data collection that overcomes some of the limitations cited in classic problem solving research while balancing a search for fundamental understanding with the possibility of application. The methodology described in this study employs an electroencephalographic (EEG) headset, as part of a mixed methods approach, to gather objective evidence of students' cognitive processing during problem solving epochs. The method described provides rich evidence of students' cognitive representations of problems during episodes of applied reasoning. The reliability and validity of the EEG method is supported by the stability of the findings across the triangulated data sources. The paper presents a novel method in the context of research within STEM education and demonstrates an effective procedure for gathering rich evidence of cognitive processing during the early stages of problem conceptualization.

  11. Spending Analysis of Government Purchase Card Buys for United States Navy Destroyers

    DTIC Science & Technology

    2009-12-01

    1). By utilizing Simplified 2 Acquisition Procedures (SAP) and Electronic Funds Transfer ( EFT ), governmental entities including the Department...policy or regulation is unclear. While this is in essence no different from the relationship as it exists regarding stock -numbered supply system...invoice cited the purchased material only using a local stock number, e.g., 3ea Item 32-4405N $75, purchase card requests and amplifying

  12. Army Financial Improvement Plans Generally Managed Effectively, but Better Contract Management Needed

    DTIC Science & Technology

    2014-04-08

    assertions are free of material misstatement . There are two types of substantive testing: substantive analytical procedures and tests of details...identified internal control weaknesses continue to exist and are significant enough to result in material misstatements or a conclusion that account...records properly. As a result, CEHNC personnel processed $21.5 million in contractor payments, citing an incorrect obligation, and was at increased risk

  13. The 50 Most Cited Articles in Invasive Neuromodulation.

    PubMed

    Ward, Max; Doran, Joseph; Paskhover, Boris; Mammis, Antonios

    2018-06-01

    Bibliometric analysis is a commonly used analytic tool for objective determination of the most influential and peer-recognized articles within a given field. This study is the first bibliometric analysis of the literature in the field of invasive neuromodulation, excluding deep brain stimulation. The objectives of this study are to identify the 50 most cited articles in invasive neuromodulation, provide an overview of the literature to assist in clinical education, and evaluate the effect of impact factor on manuscript recognition. Bibliometric analysis was performed using the Science Citation Index from the Institute for Scientific Information, accessed through the Web of Science. Search terms relevant to the field of invasive neuromodulation were used to identify the 50 most cited journal articles between 1900 and 2016. The median number of citations was 236 (range, 173-578). The most common topics among the articles were vagus nerve stimulation (n = 24), spinal cord stimulation (n = 9), and motor cortex stimulation (n = 6). Median journal impact factor was 5.57. Most of these articles (n = 19) contained level I, II, or III evidence. This analysis provides a brief look into the most cited articles within the field, many of which evaluated innovated procedures and therapies that helped to drive surgical neuromodulation forward. These landmark articles contain vital clinical and educational information that remains relevant to clinicians and students within the field and provide insight into areas of expanding research. Journal impact factor may play a significant role in determining the literary relevance and general awareness of invasive neuromodulation studies. Copyright © 2018 Elsevier Inc. All rights reserved.

  14. The Behavioral Economics of Choice and Interval Timing

    PubMed Central

    Jozefowiez, J.; Staddon, J. E. R.; Cerutti, D. T.

    2009-01-01

    We propose a simple behavioral economic model (BEM) describing how reinforcement and interval timing interact. The model assumes a Weber-law-compliant logarithmic representation of time. Associated with each represented time value are the payoffs that have been obtained for each possible response. At a given real time, the response with the highest payoff is emitted. The model accounts for a wide range of data from procedures such as simple bisection, metacognition in animals, economic effects in free-operant psychophysical procedures and paradoxical choice in double-bisection procedures. Although it assumes logarithmic time representation, it can also account for data from the time-left procedure usually cited in support of linear time representation. It encounters some difficulties in complex free-operant choice procedures, such as concurrent mixed fixed-interval schedules as well as some of the data on double bisection, that may involve additional processes. Overall, BEM provides a theoretical framework for understanding how reinforcement and interval timing work together to determine choice between temporally differentiated reinforcers. PMID:19618985

  15. Empirical null estimation using zero-inflated discrete mixture distributions and its application to protein domain data.

    PubMed

    Gauran, Iris Ivy M; Park, Junyong; Lim, Johan; Park, DoHwan; Zylstra, John; Peterson, Thomas; Kann, Maricel; Spouge, John L

    2017-09-22

    In recent mutation studies, analyses based on protein domain positions are gaining popularity over gene-centric approaches since the latter have limitations in considering the functional context that the position of the mutation provides. This presents a large-scale simultaneous inference problem, with hundreds of hypothesis tests to consider at the same time. This article aims to select significant mutation counts while controlling a given level of Type I error via False Discovery Rate (FDR) procedures. One main assumption is that the mutation counts follow a zero-inflated model in order to account for the true zeros in the count model and the excess zeros. The class of models considered is the Zero-inflated Generalized Poisson (ZIGP) distribution. Furthermore, we assumed that there exists a cut-off value such that smaller counts than this value are generated from the null distribution. We present several data-dependent methods to determine the cut-off value. We also consider a two-stage procedure based on screening process so that the number of mutations exceeding a certain value should be considered as significant mutations. Simulated and protein domain data sets are used to illustrate this procedure in estimation of the empirical null using a mixture of discrete distributions. Overall, while maintaining control of the FDR, the proposed two-stage testing procedure has superior empirical power. 2017 The Authors. Biometrics published by Wiley Periodicals, Inc. on behalf of International Biometric Society This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

  16. In Defence of Bureaucratic Organisation in Education.

    ERIC Educational Resources Information Center

    Lungu, Gatian F.

    1985-01-01

    Examines the charges against bureaucracy in education. Cites research studies in arguing that bureaucracy is needed to arbitrate conflicts from an impartial perspective and that problems are failures in application and not of bureaucracies themselves. (MLF)

  17. 78 FR 71660 - Zizhuang Li, M.D.; Decision and Order

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-29

    ... Show Cause Order proposed the denial of Applicant's application for a DEA Certificate of Registration... interest.'' Id. at 1 (citing 21 U.S.C. 823(f)). As basis for the denial, the Show Cause Order alleged that... Government queried the Postal Service's Track and Confirm Web page and determined that the mailing had not...

  18. 48 CFR 970.2903-2 - Application of State and local taxes to the Government.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Application of State and local taxes to the Government. It is DOE policy to secure those immunities or... to preclude payment of any taxes for which any of the immunities or exemptions cited in this subpart are available. Advice of Counsel should be sought as to the availability of such immunities or...

  19. 48 CFR 970.2903-2 - Application of State and local taxes to the Government.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Application of State and local taxes to the Government. It is DOE policy to secure those immunities or... to preclude payment of any taxes for which any of the immunities or exemptions cited in this subpart are available. Advice of Counsel should be sought as to the availability of such immunities or...

  20. 48 CFR 970.2903-2 - Application of State and local taxes to the Government.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Application of State and local taxes to the Government. It is DOE policy to secure those immunities or... to preclude payment of any taxes for which any of the immunities or exemptions cited in this subpart are available. Advice of Counsel should be sought as to the availability of such immunities or...

  1. 48 CFR 970.2903-2 - Application of State and local taxes to the Government.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Application of State and local taxes to the Government. It is DOE policy to secure those immunities or... to preclude payment of any taxes for which any of the immunities or exemptions cited in this subpart are available. Advice of Counsel should be sought as to the availability of such immunities or...

  2. 48 CFR 970.2903-2 - Application of State and local taxes to the Government.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Application of State and local taxes to the Government. It is DOE policy to secure those immunities or... to preclude payment of any taxes for which any of the immunities or exemptions cited in this subpart are available. Advice of Counsel should be sought as to the availability of such immunities or...

  3. A pre- and post-intervention study of infection control in equine hospitals in Sweden

    PubMed Central

    2014-01-01

    Background Detection of nosocomial methicillin-resistant Staphylococcus aureus infections in horses in Sweden has increased attention on infection control (IC) in equine hospitals. This study established baseline data on IC programmes within such settings, evaluated compliance with some IC procedures before and after an education intervention, and examined barriers to compliance. The study was carried out between 2008 and 2011 in four Swedish equine hospitals. Data on current IC of each hospital, purchase data on hand sanitisers and disposable gloves per patient, and direct observations of compliance with procedures were monitored pre- and post-intervention. The intervention comprised a lecture on common IC and a review of each hospital’s current procedures. For comparison, retrospective purchase data were reviewed. A questionnaire on individual compliance, experiences and opinions of IC was issued to employees. Results Three hospitals completed the study, while the fourth reported its IC procedures and completed the questionnaire. Actual numbers of procedures, content and level of documentation differed among the hospitals. Similarities were poor or absent IC implementation strategy, lack of active surveillance of compliance with procedures and no monitoring of such as nosocomial infections. Among the hospitals which completed the study, two reported pre-intervention observation of compliance, while all three reported post-intervention observations. The purchase data showed trends for changes over time, although not uniformly related to the intervention. One hospital demonstrated a significant post-intervention increase in compliance with glove procedures, accompanied by a non-significant post-intervention increase in purchases figures. Compliance with dress code and personal appearance was high in all three hospitals (92-100%), while compliance with hand hygiene procedures was generally poorer. Barriers to compliance cited in the questionnaire (data from four hospitals) included insufficient supplies of hygiene products, lack of readily accessible places for cleaning, insufficient knowledge and high workload. Conclusions Potential for easily attainable improvements in IC, such as traceability of documents, implementation strategies and surveillance of efficacy, was revealed. Attention to hand hygiene implementation and improvement of logistics appeared important. Data on purchases per patient were readily available and therefore applicable for intra-hospital surveillance of IC trends over time. PMID:25146752

  4. Software Attribution for Geoscience Applications in the Computational Infrastructure for Geodynamics

    NASA Astrophysics Data System (ADS)

    Hwang, L.; Dumit, J.; Fish, A.; Soito, L.; Kellogg, L. H.; Smith, M.

    2015-12-01

    Scientific software is largely developed by individual scientists and represents a significant intellectual contribution to the field. As the scientific culture and funding agencies move towards an expectation that software be open-source, there is a corresponding need for mechanisms to cite software, both to provide credit and recognition to developers, and to aid in discoverability of software and scientific reproducibility. We assess the geodynamic modeling community's current citation practices by examining more than 300 predominantly self-reported publications utilizing scientific software in the past 5 years that is available through the Computational Infrastructure for Geodynamics (CIG). Preliminary results indicate that authors cite and attribute software either through citing (in rank order) peer-reviewed scientific publications, a user's manual, and/or a paper describing the software code. Attributions maybe found directly in the text, in acknowledgements, in figure captions, or in footnotes. What is considered citable varies widely. Citations predominantly lack software version numbers or persistent identifiers to find the software package. Versioning may be implied through reference to a versioned user manual. Authors sometimes report code features used and whether they have modified the code. As an open-source community, CIG requests that researchers contribute their modifications to the repository. However, such modifications may not be contributed back to a repository code branch, decreasing the chances of discoverability and reproducibility. Survey results through CIG's Software Attribution for Geoscience Applications (SAGA) project suggest that lack of knowledge, tools, and workflows to cite codes are barriers to effectively implement the emerging citation norms. Generated on-demand attributions on software landing pages and a prototype extensible plug-in to automatically generate attributions in codes are the first steps towards reproducibility.

  5. DNA barcoding in a biodiversity hot spot: potential value for the identification of Malagasy Euphorbia L. listed in CITES Appendices I and II.

    PubMed

    Aubriot, Xavier; Lowry, Porter P; Cruaud, Corinne; Couloux, Arnaud; Haevermans, Thomas

    2013-01-01

    The island of Madagascar is a key hot spot for the genus Euphorbia, with at least 170 native species, almost all endemic. Threatened by habitat loss and illegal collection of wild plants, nearly all Malagasy Euphorbia are listed in CITES Appendices I and II. The absence of a reliable taxonomic revision makes it particularly difficult to identify these plants, even when fertile, and thereby compromises the application of CITES regulations. DNA barcoding, which can facilitate species-level identification irrespective of developmental stage and the presence of flowers or fruits, may be a promising tool for monitoring and controlling trade involving threatened species. In this study, we test the potential value of barcoding on 41 Euphorbia species representative of the genus in Madagascar, using the two widely adopted core barcode markers (matK and rbcL), along with two additional DNA regions, nuclear internal transcribed spacer (ITS) and the chloroplastic intergenic spacer psbA-trnH. For each marker and for selected marker combinations, inter- and intraspecific distance estimates and species discrimination rates are calculated. Results using just the 'official' barcoding markers yield overlapping inter- and intraspecific ranges and species discrimination rates below 60%. When ITS is used, whether alone or in combination with the core markers, species discrimination increases to nearly 100%, whereas the addition of psbA-trnH produces less satisfactory results. This study, the first ever to test barcoding on the large, commercially important genus Euphorbia shows that this method could be developed into a powerful identification tool and thereby contribute to more effective application of CITES regulations. © 2012 Blackwell Publishing Ltd.

  6. [Gaps of Evidence in ENT-Surgery - a Qualitative Survey].

    PubMed

    Löhler, J; Akcicek, B; Müller, F; Dreier, G; Meerpohl, J J; Vach, W; Werner, J

    2016-04-01

    As in other disciplines, the burgeoning knowledge in ENT medicine long ago surpassed our ability to adequately absorb it and maintain a proper overview. This can give rise to actual or assumed knowledge gaps that can impede the progress of the discipline and evidence-based treatment of patients. Clinics and medical practices also hold to traditional doctrines that shape day-to-day medicine, without these schools being challenged based on evidence. Between February and June 2015, 160 ENT clinics, including 34 university hospitals, and 2,670 ENT practices took part in a two-arm online survey on existing or perceived evidentiary gaps in ENT medicine using a previously development questionnaire. The survey used for half the participants was open in form; the other half were given a closed survey with systematics of the field for orientation. The survey was augmented with additional data such as the number of publications and focus areas in the clinics and the age and type of practice of the established physicians. The return rate from the clinics was 39.7%; the return rate of the closed surveys was 29.3%. Of the physicians in medical practice, 14.6% responded to the closed and 18.6% to the open survey. There were no major differences between the two forms of survey. Otological and oncological issues comprised approximately 30% of the list of answers from clinics. Corresponding questions were formulated regarding the current diagnostic and therapeutic problems, such as with stage-related tumor treatment or implantable hearing aids. Diagnostic procedures, e.g., special new procedures in audiology and vestibulogy, dominated the surveys from the practices. However clinics and practices alike cited marginal areas of the discipline that are of daily relevance. The cited knowledge gaps then needed to be verified or refuted and clarified based on research of the literature as to whether the existing evidence actually reached healthcare providers in the form of guidelines, publications, conferences or continuing training for application in daily practice. Other steps would include prioritizing future research, evidence mapping, deciding on further systematic reviews, and targeted studies in conjunction with procuring third-party funding and in cooperation with patient associations. The knowledge thus gained should ultimately be transferred in improved form for application in daily clinical practice. Ten questions of key importance each needed to be formulated for the hospitals and practices. © Georg Thieme Verlag KG Stuttgart · New York.

  7. 40 CFR 152.92 - Submission of a new valid study.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Submitters' Rights § 152.92 Submission of a new valid study. An applicant may demonstrate compliance for a... study previously submitted to the Agency should not be resubmitted but should be cited in accordance...

  8. Torch kit for welding in difficult areas

    NASA Technical Reports Server (NTRS)

    Stein, J. A.

    1971-01-01

    Miniature tungsten inert gas welding torch, used with variously formed interchangeable soft copper tubing extensions, provides inexpensive, accurate welding capability for inaccessible joints. Kit effectively welds stainless steel tubing 0.089 cm thick. Other applications are cited.

  9. Analytical Electrochemistry: Methodology and Applications of Dynamic Techniques.

    ERIC Educational Resources Information Center

    Heineman, William R.; Kissinger, Peter T.

    1980-01-01

    Reports developments involving the experimental aspects of finite and current analytical electrochemistry including electrode materials (97 cited references), hydrodynamic techniques (56), spectroelectrochemistry (62), stripping voltammetry (70), voltammetric techniques (27), polarographic techniques (59), and miscellany (12). (CS)

  10. Design considerations for fiber composite structures

    NASA Technical Reports Server (NTRS)

    Chamis, C. C.

    1972-01-01

    An overview of the design methodology for designing structural components from fiber composites is presented. In particular, the need for new conceptual structural designs for the future is discussed and the evolution of conceptual design is illustrated. Sources of design data, analysis and design procedures, and the basic components of structural fiber composites are cited and described. Examples of tradeoff studies and optimum designs are discussed and a simple structure is described in some detail.

  11. Moderate severity heart failure does not involve a downregulation of myocardial fatty acid oxidation

    DTIC Science & Technology

    2004-10-01

    malonyl-CoA-sensitive form of carnitine palmitoyltransferase is not local - ized exclusively in the outer membrane of rat liver mitochondria . J Biol...for the isolation of fresh mitochondria , both subsarcolemmal and interfibrillar. Analytic methods. Detailed analytic methods have been previously cited...populations of mitochondria , the subsarcolemmal and inter- fibrillar, were isolated from hearts of normal and HF dogs using the procedure of Palmer et al

  12. Customer complaints in the National Health Service.

    PubMed

    Reid, N; Reid, R; Morris, D

    1995-11-01

    This paper addresses the role of consumer complaints in the flourishing quality assurance industry within the National Health Service (NHS), and considers the traditional ethos of complaints within the service. The advent of the internal market is considered as one of a range of factors which may change attitudes of NHS staff to complaints. In evaluating how complaints services might develop relevant literature is reviewed and recent national data on complaints procedures are cited.

  13. A Comprehensive Look at the North Atlantic Treaty Organization Mutual Support Act of 1979

    DTIC Science & Technology

    1989-04-01

    NMSA "Ceiling" Authority a) Generally 23 b) Reimbursable Acquisitions 25 c) Reimbursable Transfers 26 3. Reporting Requirements 26 4. Limited... Reimbursable Transactions 48 c) Nonreimbursable Transactions 49 d) Crediting of Receipts 50 * 2. Pricing a) Generally 51 b) Reimbursable Transactions (1...our 84 allies in the past. In addition to the three authorities cited above, the NMSA also establishes pricing and reimbursement procedures which

  14. Aspects of dento/medico-legal report writing.

    PubMed

    Wood, Geoff D

    2014-03-01

    This paper offers some guidance on aspects of dento/medico-legal report writing, citing anonymized examples from the author's caseload for clarification of the points made, and also serves to illustrate that sometimes not everything is as straightforward as it may initially appear. It provides reference to the current Civil Procedure Rules in England and Wales and its relevance in report writing. To provide guidance on aspects of dento/medico-legal report writing.

  15. Informed consent: not just for procedures anymore.

    PubMed

    Feld, Andrew D

    2004-06-01

    The ethical and legal requirement to obtain informed consent prior to performing a procedure or administering a treatment derives from the concept of personal (patient) autonomy. The competent patient, after receiving appropriate disclosure of the material risks of the procedure or treatment, understanding those risks, the benefits, and the alternative approaches, makes a voluntary and uncoerced informed decision to proceed. This article will present a general overview of the modern concept of informed consent as a process (mutual communication) rather than an event (document signing). The historical evolution of this concept and the legal rulings that have shaped the requirements of informed consent will be cited. The benefits of informed decision making as a communication and risk management tool are presented. This review is intended as general information, and not as legal advice, which should be sought from a health-care attorney.

  16. A Multiscale Vision Model and Applications to Astronomical Image and Data Analyses

    NASA Astrophysics Data System (ADS)

    Bijaoui, A.; Slezak, E.; Vandame, B.

    Many researches were carried out on the automated identification of the astrophy sical sources, and their relevant measurements. Some vision models have been developed for this task, their use depending on the image content. We have developed a multiscale vision model (MVM) \\cite{BR95} well suited for analyzing complex structures such like interstellar clouds, galaxies, or cluster of galaxies. Our model is based on a redundant wavelet transform. For each scale we detect significant wavelet coefficients by application of a decision rule based on their probability density functions (PDF) under the hypothesis of a uniform distribution. In the case of a Poisson noise, this PDF can be determined from the autoconvolution of the wavelet function histogram \\cite{SLB93}. We may also apply Anscombe's transform, scale by scale in order to take into account the integrated number of events at each scale \\cite{FSB98}. Our aim is to compute an image of all detected structural features. MVM allows us to build oriented trees from the neighbouring of significant wavelet coefficients. Each tree is also divided into subtrees taking into account the maxima along the scale axis. This leads to identify objects in the scale space, and then to restore their images by classical inverse methods. This model works only if the sampling is correct at each scale. It is not generally the case for the orthogonal wavelets, so that we apply the so-called `a trous algorithm \\cite{BSM94} or a specific pyramidal one \\cite{RBV98}. It leads to ext ract superimposed objets of different size, and it gives for each of them a separate image, from which we can obtain position, flux and p attern parameters. We have applied these methods to different kinds of images, photographic plates, CCD frames or X-ray images. We have only to change the statistical rule for extr acting significant coefficients to adapt the model from an image class to another one. We have also applied this model to extract clusters hierarchically distributed or to identify regions devoid of objects from galaxy counts.

  17. Combining Approach in Stages with Least Squares for fits of data in hyperelasticity

    NASA Astrophysics Data System (ADS)

    Beda, Tibi

    2006-10-01

    The present work concerns a method of continuous approximation by block of a continuous function; a method of approximation combining the Approach in Stages with the finite domains Least Squares. An identification procedure by sub-domains: basic generating functions are determined step-by-step permitting their weighting effects to be felt. This procedure allows one to be in control of the signs and to some extent of the optimal values of the parameters estimated, and consequently it provides a unique set of solutions that should represent the real physical parameters. Illustrations and comparisons are developed in rubber hyperelastic modeling. To cite this article: T. Beda, C. R. Mecanique 334 (2006).

  18. On recent advances and future research directions for computational fluid dynamics

    NASA Technical Reports Server (NTRS)

    Baker, A. J.; Soliman, M. O.; Manhardt, P. D.

    1986-01-01

    This paper highlights some recent accomplishments regarding CFD numerical algorithm constructions for generation of discrete approximate solutions to classes of Reynolds-averaged Navier-Stokes equations. Following an overview of turbulent closure modeling, and development of appropriate conservation law systems, a Taylor weak-statement semi-discrete approximate solution algorithm is developed. Various forms for completion to the final linear algebra statement are cited, as are a range of candidate numerical linear algebra solution procedures. This development sequence emphasizes the key building blocks of a CFD RNS algorithm, including solution trial and test spaces, integration procedure and added numerical stability mechanisms. A range of numerical results are discussed focusing on key topics guiding future research directions.

  19. Financial Aid Administrators' Views on Simplifying Financial Aid: NASFAA's 2008 Financial Aid Simplification Survey Report

    ERIC Educational Resources Information Center

    National Association of Student Financial Aid Administrators (NJ1), 2008

    2008-01-01

    Despite a decade of simplification efforts, students and families are often still baffled by the student aid process and cringe at the sight of financial aid application forms. Contrary to its purpose of helping students to access college, the student aid application process causes families frustration and confusion that has been cited as an…

  20. Land Application of Wastes: An Educational Program. Case Studies Reviewed - Module 14.

    ERIC Educational Resources Information Center

    Clarkson, W. W.; And Others

    This module provides information about 14 existing land application systems. Each case study gives the location and description of the system, volume treated, climate and soil type, cost, land area, and other data. A brief comment about the system is given as well as a more detailed discussion. References are cited which may be used to examine 100…

  1. 77 FR 28860 - Notice of Availability of Government-Owned Inventions; Available for Licensing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-16

    .../372,755: Foam Free Testing Systems and Methods, Navy Case No. 101448//U.S. Patent Application No. 7,372,712: Foam Free Testing Systems and Methods. ADDRESSES: Requests for copies of the inventions cited...

  2. Data Banks; Bibliography.

    ERIC Educational Resources Information Center

    van der Aa, H. J., Comp.; And Others

    This 249 item, mostly annotated bibliography cites literature on the general themes of basic principles, hardware, software and application studies of data bases. The broad categories are principles, development possibilities, organizational design, bibliographies, economic aspects, data structure-design, file organization, programing, aviation,…

  3. Which articles and which topics in the forensic sciences are most highly cited?

    PubMed

    Jones, A W

    2005-01-01

    Forensic science is a multidisciplinary field, which covers many branches of the pure, the applied and the biomedical sciences. Writing-up and publishing research findings helps to enhance the reputation of the investigators and the laboratories where the work was done. The number of times an article is cited in the reference lists of other articles is generally accepted as a mark of distinction. Indeed, citation analysis has become widely used in research assessment of individual scientists, university departments and entire nations. This article concerns the most highly cited papers published in the Journal of Forensic Sciences (JFS) between 1956 and 2005. These were identified with the help of Web-of-Science, which is the on-line version of Science Citation Index, produced by Thomson Institute for Scientific Information (Thomson ISI) with head offices in Philadelphia, USA. This database tracks, among other things, the annual citation records of articles published in several thousand scientific journals worldwide. Those JFS articles accumulating 50 or more citations were identified and rank-ordered according to the total number of citations. These articles were also evaluated according to the name of first author, the subject category of the article, the country of origin and the pattern of co-authorship. This search strategy located 46 articles cited between 50 and 292 times since they first appeared in print. The most highly cited paper by far was by Kasai, Nakamura and White (USA and Japan) concerning DNA profiling and the application of the polymerase chain reaction (PCR) in forensic science. Some forensic scientists appeared as first author on two to three highly cited articles, namely Wetli (USA), Budowle (USA) and Comey (USA). When the highly cited articles were sub-divided into subject category, 15 were identified as coming from toxicology, closely followed by criminalistics (14 articles), pathology (nine articles), physical anthropology (five articles), forensic psychiatry (two articles) and one from odontology. The number of co-authors on these highly cited articles ranged from one to nine and the names of some investigators appeared on as many as four highly cited papers. The vast majority of papers originated from US laboratories although five came from Japan, two each from Sweden and Canada and there was also a joint USA-Swiss collaboration. The Thompson ISI citation databases provide unique tools for tracking citations to individual articles and impact and citation records of scholarly journals.

  4. The constitutional protection of trade secrets and patents under the Biologics Price Competition and Innovation Act of 2009.

    PubMed

    Epstein, Richard A

    2011-01-01

    The Biologics Price Competition and Innovation Act of 2009 ("Biosimilars Act") is for the field of pharmaceutical products the single most important legislative development since passage of the Drug Price Competition and Patent Term Restoration Act of 1984 ("Hatch-Waxman Act"), on which portions of the Biosimilars Act are clearly patterned. Congress revised section 351 of the Public Health Service Act (PHSA) to create a pathway for FDA approval of "biosimilar" biological products. Each biosimilar applicant is required to cite in its application a "reference product" that was approved on the basis of a full application containing testing data and manufacturing information, which is owned and was submitted by another company and much of which constitutes trade secret information subject to constitutional protection. Because the Biosimilars Act authorizes biosimilar applicants to cite these previously approved applications, the implementation of the new legislative scheme raises critical issues under the Fifth Amendment of the Constitution, pursuant to which private property--trade secrets included--may not be taken for public use, without "just compensation." FDA must confront those issues as it implements the scheme set out in the Biosimilars Act. This article will discuss these issues, after providing a brief overview of the Biosimilars Act and a more detailed examination of the law of trade secrets.

  5. Going, going, still there: using the WebCite service to permanently archive cited Web pages.

    PubMed

    Eysenbach, Gunther

    2006-01-01

    Scholars are increasingly citing electronic "web references" which are not preserved in libraries or full text archives. WebCite is a new standard for citing web references. To "webcite" a document involves archiving the cited Web page through www.webcitation.org and citing the WebCite permalink instead of (or in addition to) the unstable live Web page.

  6. Production and citation of cochrane systematic reviews: a bibliometrics analysis.

    PubMed

    Shen, Jiantong; Li, Youping; Clarke, Mike; Du, Liang; Wang, Li; Zhong, Dake

    2014-05-06

    To evaluate the production and utilization of Cochrane systematic reviews(CSRs) and to analyze its influential factors, so as to improve the capacity of translating CSRs into practice. All CSRs and protocols were retrieved from the Cochrane Library ISSUE 2, 2011 and citation data were retrieved from SCI database. Citation analysis was used to analyze the situation of CSRs production and utilization. CSR publication had grown from an annual average of 32 to 718 documents. Only one developing country was among the ten countries with the largest amount of publications. High income countries accounted for 83% of CSR publications and 90.8% of cited counts. 34.7% of CSRs had a cited count of 0, while only 0.9% had been cited more than 50 times. Highly cited CSRs were published in England, Australia, Canada, USA and other high income countries. The countries with a Cochrane center or a Cochrane methodology group had a greater capability of CSRs production and citing than others. The CSRs addressing the topics of diseases were more than those targeted at public health issues. There was a big gap in citations of different interventions even for the same topic. The capability of CSR production and translation grew rapidly, but varied among countries and institutions, which was affected by several factors such as the capability of research, the resourcesand the applicability of the evidence. It is important to improve evidence translation through educating, training and prioritizing the problems based on real demands of end user. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

  7. 75 FR 60464 - Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-30

    ...)(6). Grant applications for the Advancing Patient Safety with Simulation Research Mechanism (R18... disclosure under the above-cited statutes. SEP Meeting on: Advancing Patient Safety with Simulation Research... contact Mrs. Bonnie Campbell, Committee Management Officer, Office of Extramural Research, Education and...

  8. The Role of Problem-Based Learning in the Enhancement of Allied Health Education.

    ERIC Educational Resources Information Center

    Tavakol, Kamran; Reicherter, E. Anne

    2003-01-01

    Analyzes the literature on problem-based learning (PBL) and explains its rationale, process, and current outcomes research. Cites examples of PBL in medical education and its application to allied health education. (Contains 49 references.) (JOW)

  9. The Contribution of Developmental Behavioural Genetics towards a Multifactorial Understanding of Reading Disabilities.

    ERIC Educational Resources Information Center

    Crawford, Shawn; And Others

    1990-01-01

    The utility of developmental behavioral genetics in the study of reading disability is considered. Research which has found reading disability to be partly genetically determined is cited, and future research applications are discussed. (Author/JDD)

  10. Publications of the U.S. Army Engineer Research and Development Center; Appendix B: January 2017-December 2017

    DTIC Science & Technology

    2018-06-04

    are listed. The publications are grouped according to the technical laboratories or technical program for which they were prepared. Procedures for...obtaining ERDC reports are included in the Preface. DISCLAIMER: The contents of this report are not to be used for advertising, publication, or...names and trademarks cited are the property of their respective owners. The findings of this report are not to be construed as an official

  11. Proposed design procedure for transmission shafting under fatigue loading

    NASA Technical Reports Server (NTRS)

    Loewenthal, S. H.

    1978-01-01

    A new standard for the design of transmission shafting is reported. Computed was the diameter of rotating solid steel shafts under combined cyclic bending and steady torsion is presented. The formula is based on an elliptical variation of endurance strength with torque exhibited by combined stress fatigue data. Fatigue factors are cited to correct specimen bending endurance strength data for use in the shaft formula. A design example illustrates how the method is to be applied.

  12. RCRA, superfund and EPCRA hotline training module. Introduction to: RCRA enforcement and compliance updated July 1996

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    1996-07-01

    The module describes enforcement procedures and cites the statutory authority and describes the two different types of enforcement (i.e., administrative and judicial). It explains when and how EPA can enforce the RCRA regulations in authorized states. It describes the enforcement mechanisms available to EPA. It states the differences between enforcement at interim status and permitted facilities. It describes enforcement at federal facilities and identifies relevant resource documents.

  13. RCRA/UST, superfund, and EPCRA hotline training module. Introduction to: RCRA enforcement and compliance, update as of July 1995

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    1995-11-01

    The module describds enforcement procedures and cites the statutory authority. It describes the two different types of enforcement (i.e., administrative and judicial) and explains when and how EPA can enforce the RCRA regulations in authorized states. It describes the enforcement mechanisms available to EPA. It states the differences between enforcement at interim status, permitted facilities, and Federal facilities. It also identifies relevant resources documents.

  14. Spectrophotometric determination of some histamine H1-antagonists drugs in their pharmaceutical preparations.

    PubMed

    Hassan, Wafaa S; El-Henawee, Magda M; Gouda, Ayman A

    2008-01-01

    Two rapid, simple and sensitive extractive specrophotometric methods has been developed for the determination of three histamine H1-antagonists drugs, e.g., chlorphenoxamine hydrochloride (CPX), diphenhydramine hydrochloride (DPH) and clemastine (CMT) in bulk and in their pharmaceutical formulations. The first method depend upon the reaction of molybdenum(V) thiocyanate ions (Method A) with the cited drugs to form stable ion-pair complexes which extractable with methylene chloride, the orange red color complex was determined colorimetrically at lambda(max) 470nm. The second method is based on the formation of an ion-association complex with alizarin red S as chromogenic reagents in acidic medium (Method B), which is extracted into chloroform. The complexes have a maximum absorbance at 425 and 426nm for (DPH or CMT) and CPX, respectively. Regression analysis of Beer-Lambert plots showed a good correlation in the concentration ranges of 5.0-40 and 5-70microgmL(-1) for molybdenum(V) thiocyanate (Method A) and alizarin red S (Method B), respectively. For more accurate analysis, Ringbom optimum concentration ranges were calculated. The molar absorptivity, Sandell sensitivity, detection and quantification limits were calculated. Applications of the procedure to the analysis of various pharmaceutical preparations gave reproducible and accurate results. Further, the validity of the procedure was confirmed by applying the standard addition technique and the results obtained in good agreement well with those obtained by the official method.

  15. Spectrophotometric determination of some histamine H1-antagonists drugs in their pharmaceutical preparations

    NASA Astrophysics Data System (ADS)

    Hassan, Wafaa S.; El-Henawee, Magda M.; Gouda, Ayman A.

    2008-01-01

    Two rapid, simple and sensitive extractive specrophotometric methods has been developed for the determination of three histamine H1-antagonists drugs, e.g., chlorphenoxamine hydrochloride (CPX), diphenhydramine hydrochloride (DPH) and clemastine (CMT) in bulk and in their pharmaceutical formulations. The first method depend upon the reaction of molybdenum(V) thiocyanate ions (Method A) with the cited drugs to form stable ion-pair complexes which extractable with methylene chloride, the orange red color complex was determined colorimetrically at λmax 470 nm. The second method is based on the formation of an ion-association complex with alizarin red S as chromogenic reagents in acidic medium (Method B), which is extracted into chloroform. The complexes have a maximum absorbance at 425 and 426 nm for (DPH or CMT) and CPX, respectively. Regression analysis of Beer-Lambert plots showed a good correlation in the concentration ranges of 5.0-40 and 5-70 μg mL -1 for molybdenum(V) thiocyanate (Method A) and alizarin red S (Method B), respectively. For more accurate analysis, Ringbom optimum concentration ranges were calculated. The molar absorptivity, Sandell sensitivity, detection and quantification limits were calculated. Applications of the procedure to the analysis of various pharmaceutical preparations gave reproducible and accurate results. Further, the validity of the procedure was confirmed by applying the standard addition technique and the results obtained in good agreement well with those obtained by the official method.

  16. Providing long-acting reversible contraception services in Seattle school-based health centers: key themes for facilitating implementation.

    PubMed

    Gilmore, Kelly; Hoopes, Andrea J; Cady, Janet; Amies Oelschlager, Anne-Marie; Prager, Sarah; Vander Stoep, Ann

    2015-06-01

    The purpose of this study was to describe the implementation of a program that provides long-acting reversible contraception (LARC) services within school-based health centers (SBHCs) and to identify barriers and facilitators to implementation as reported by SBHC clinicians and administrators, public health officials, and community partners. We conducted 14 semistructured interviews with key informants involved in the implementation of LARC services. Key informants included SBHC clinicians and administrators, public health officials, and community partners. We used a content analysis approach to analyze interview transcripts for themes. We explored barriers to and facilitators of LARC service delivery across and within key informant groups. The most cited barriers across key informant groups were as follows: perceived lack of provider procedural skills and bias and negative attitudes about LARC methods. The most common facilitators identified across groups were as follows: clear communication strategies, contraceptive counseling practice changes, provider trainings, and stakeholder engagement. Two additional barriers emerged in specific key informant groups. Technical and logistical barriers to LARC service delivery were cited heavily by SBHC administrative staff, community partners, and public health officials. Expense and billing was a major barrier to SBHC administrative staff. LARC counseling and procedural services can be implemented in an SBHC setting to promote access to effective contraceptive options for adolescent women. Copyright © 2015 Society for Adolescent Health and Medicine. Published by Elsevier Inc. All rights reserved.

  17. Absolute Magnitude Calibration for Dwarfs Based on the Colour-Magnitude Diagrams of Galactic Clusters

    NASA Astrophysics Data System (ADS)

    Karaali, S.; Gökçe, E. Yaz; Bilir, S.; Güçtekin, S. Tunçel

    2014-07-01

    We present two absolute magnitude calibrations for dwarfs based on colour-magnitude diagrams of Galactic clusters. The combination of the Mg absolute magnitudes of the dwarf fiducial sequences of the clusters M92, M13, M5, NGC 2420, M67, and NGC 6791 with the corresponding metallicities provides absolute magnitude calibration for a given (g - r)0 colour. The calibration is defined in the colour interval 0.25 ≤ (g - r)0 ≤ 1.25 mag and it covers the metallicity interval - 2.15 ≤ [Fe/H] ≤ +0.37 dex. The absolute magnitude residuals obtained by the application of the procedure to another set of Galactic clusters lie in the interval - 0.15 ≤ ΔMg ≤ +0.12 mag. The mean and standard deviation of the residuals are < ΔMg > = - 0.002 and σ = 0.065 mag, respectively. The calibration of the MJ absolute magnitude in terms of metallicity is carried out by using the fiducial sequences of the clusters M92, M13, 47 Tuc, NGC 2158, and NGC 6791. It is defined in the colour interval 0.90 ≤ (V - J)0 ≤ 1.75 mag and it covers the same metallicity interval of the Mg calibration. The absolute magnitude residuals obtained by the application of the procedure to the cluster M5 ([Fe/H] = -1.40 dex) and 46 solar metallicity, - 0.45 ≤ [Fe/H] ≤ +0.35 dex, field stars lie in the interval - 0.29 and + 0.35 mag. However, the range of 87% of them is rather shorter, - 0.20 ≤ ΔMJ ≤ +0.20 mag. The mean and standard deviation of all residuals are < ΔMJ > =0.05 and σ = 0.13 mag, respectively. The derived relations are applicable to stars older than 4 Gyr for the Mg calibration, and older than 2 Gyr for the MJ calibration. The cited limits are the ages of the youngest calibration clusters in the two systems.

  18. Findings From the National Machine Guarding Program: A Small Business Intervention: Lockout/Tagout.

    PubMed

    Parker, David L; Yamin, Samuel C; Xi, Min; Brosseau, Lisa M; Gordon, Robert; Most, Ivan G; Stanley, Rodney

    2016-01-01

    Failure to implement lockout/tagout (LOTO) procedures adversely affects the rate of work-related fatalities and serious traumatic injury and is one of the most frequently cited Occupational Safety and Health Administration standards. This study assesses the impact of a nationwide intervention to improve LOTO in small metal fabrication businesses. Insurance safety consultants conducted a standardized and validated evaluation of LOTO programs and procedures. Businesses received a baseline evaluation, two intervention visits, and a 12-month follow-up evaluation. The intervention was completed by 160 businesses. The mean LOTO procedure score improved from 8% to 33% (P < 0.0001), the mean program score went from 55% to 76% (P < 0.0001), and the presence of lockable disconnects went from 88% to 92% (P < 0.0001). This nationwide intervention showed substantial improvements in LOTO. It provides a framework for assessing and improving LOTO.

  19. Resource Letter CF-1: Casimir Force

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lamoreaux, S.K.

    1999-10-01

    This resource letter provides an introductory guide to the literature on the Casimir force. Journal articles and books are cited for the following topics: introductory articles and books, calculations, dynamical Casimir effect, mechanical analogs, applications, and experiments. {copyright} {ital 1999 American Association of Physics Teachers.}

  20. Proposed Standard for a Microclimate Cooling System for Emergency Responder Operations

    DTIC Science & Technology

    2012-02-17

    shock, circuit damage, overheating, fire , or explosion. If applicable, MCS vendors shall provide a certificate of compliance, which specifically cites...2, each configuration includes underwear , a duty uniform, ballistic helmet, and, boots. Table A-2 CBP PPE Configurations Configuration Components

  1. Microwave heating: Industrial applications. Citations from the Engineering Index data base

    NASA Astrophysics Data System (ADS)

    Reed, W. E.

    1980-06-01

    Industrialized uses of microwave heating are covered in 225 citations, 22 of which are new entries. The topics include industrial heating and drying for processes such as paper drying, vulcanization, and textile processing. Equipment design and safety are also cited.

  2. Predicting actual weight loss: A review of the determinants according to the theory of planned behaviour.

    PubMed

    Chung, Louisa Ming Yan; Fong, Shirley Siu Ming

    2015-01-01

    Weight reduction that corresponds with lifestyle modification is difficult to foster. The theory of planned behaviour has been actively cited in explaining health-related behaviour. This review evaluated the application of the theory of planned behaviour to weight-loss behaviour. Among the three reviewed papers, cross-sectional survey designs and subjective outcome measurements were commonly applied. All of the studies recruited obese female adults as participants, limiting the generalisability of the studies' findings. The theory of planned behaviour can be effectively applied in weight-reduction programmes targeting female obese patients. This review confirmed critiques citing the limitations of experimental studies, the subjective measurement of behaviour and short follow-up periods.

  3. Interferometry

    NASA Astrophysics Data System (ADS)

    Totzeck, Michael

    The intention of this chapter is to provide a fast and comprehensive overview of the principles of interferometry and the various types of interferometer, including interferogram evaluation and applications. Due to the age and the importance of the subject, you can find a number of monographs [16.1,2,3,4] and book chapters [16.5] in the literature. The number of original papers on optical interferometry is far too large to even attempt complete coverage in this chapter. Whenever possible, review papers are cited. Original papers are cited according to their aptness as starting points into the subject. This, however, reflects my personal judgment. Even if you do not share my opinion, you should find the references therein useful.

  4. The use of local anesthesia during dental rehabilitations: a survey of AAPD members.

    PubMed

    Townsend, Janice A; Martin, Ashla; Hagan, Joseph L; Needleman, Howard

    2013-01-01

    The purpose of this study was to document current practices among pediatric and general dentists who are members of the American Academy of Pediatric Dentistry (AAPD) regarding the use of local anesthesia (LA) on children undergoing dental rehabilitation under general anesthesia (GA). A survey was administered via e-mail to AAPD members to document the use of LA during dental rehabilitations under GA and the rationales for its use. A total of 952 of 5,599 members responded to this survey; 79 percent of respondents use LA at least part of the time during dental rehabilitations under GA. "Improved patient recovery" was the most commonly cited rationale for administering LA. Extraction of permanent and primary teeth were the two most common procedures cited for the use of LA, respectively. There is no consensus among the respondents on the use of local anesthesia during dental rehabilitation under general anesthesia, but the majority responded that it does play a role in their perioperative patient management.

  5. An intercomparison of airborne nitrogen dioxide instruments

    NASA Technical Reports Server (NTRS)

    Gregory, G. L.; Hoell, J. M., Jr.; Carroll, M. A.; Ridley, B. A.; Davis, D. D.; Bradshaw, J.; Rodgers, M. O.; Sandholm, S. T.; Schiff, H. I.; Torres, A. L.

    1990-01-01

    Results on NO2 instruments are reported from the NASA Global Tropospheric Experiment Chemical Instrumentation Test and Evaluation 2 (CITE 2) program in summer 1986. The instruments tested were (1) a two-photon LIF system using a laser for NO2-NO photolysis, (2) a chemiluminescence (CL) detector using FeSO4 for NO2-NO conversion, (3) a CL detector using an arc lamp for NO2-NO photolysis, and (4) a tunable-laser-diode multipath-absorption system. The procedures for the CITE 2 ground-based and flight tests are described in detail, and the results are presented in extensive graphs. Instrument (2) was eliminated because the FeSO4 converted atmospheric PAN to NO, resulting in spuriously high NO2 values. The remaining instruments gave readings in 30-40-percent agreement at NO2 mixing ratios of 100-200 parts per trillion by volume (pptv). At ratios below 50 pptv, the correlation among the measurements was very poor, with a tendency for system (4) to give higher values than (1) or (3).

  6. Forensic identification of CITES protected slimming cactus (Hoodia) using DNA barcoding.

    PubMed

    Gathier, Gerard; van der Niet, Timotheus; Peelen, Tamara; van Vugt, Rogier R; Eurlings, Marcel C M; Gravendeel, Barbara

    2013-11-01

    Slimming cactus (Hoodia), found only in southwestern Africa, is a well-known herbal product for losing weight. Consequently, Hoodia extracts are sought-after worldwide despite a CITES Appendix II status. The failure to eradicate illegal trade is due to problems with detecting and identifying Hoodia using morphological and chemical characters. Our aim was to evaluate the potential of molecular identification of Hoodia based on DNA barcoding. Screening of nrITS1 and psbA-trnH DNA sequences from 26 accessions of Ceropegieae resulted in successful identification, while conventional chemical profiling using DLI-MS led to inaccurate detection and identification of Hoodia. The presence of Hoodia in herbal products was also successfully established using DNA sequences. A validation procedure of our DNA barcoding protocol demonstrated its robustness to changes in PCR conditions. We conclude that DNA barcoding is an effective tool for Hoodia detection and identification which can contribute to preventing illegal trade. © 2013 American Academy of Forensic Sciences.

  7. Quality-assurance plan for the analysis of fluvial sediment by the U.S. Geological Survey Kentucky Water Science Center Sediment Laboratory

    USGS Publications Warehouse

    Shreve, Elizabeth A.; Downs, Aimee C.

    2005-01-01

    This report describes laboratory procedures used by the U.S. Geological Survey Kentucky Water Science Center Sediment Laboratory for the processing and analysis of fluvial-sediment samples for concentration of sand and finer material. The report details the processing of a sediment sample through the laboratory from receiving the sediment sample, through the analytical process, to compiling results of the requested analysis. Procedures for preserving sample integrity, calibrating and maintaining of laboratory and field instruments and equipment, analyzing samples, internal quality assurance and quality control, and validity of the sediment-analysis results also are described. The report includes a list of references cited and a glossary of sediment and quality-assurance terms.

  8. A literature survey of information on well installation and sample collection procedures used in investigations of ground-water contamination by organic compounds

    USGS Publications Warehouse

    Dumouchelle, D.H.; Lynch, E.A.; Cummings, T.R.

    1990-01-01

    A survey of literature on well installation and water-quality sampling, particularly as they relate to investigations of ground-water contamination by organic compounds, has been conducted. Library card files and computerized data bases were searched to identify journal articles, conference proceedings, technical reports, books, and other publications. Pertinent information has been extracted from 105 references; each reference is listed in a bibliography. Material contained in the report is organized by topical categories that include drilling methods and equipment, well construction, well development, sampling materials and equipment, decontamination of equipment, and sampling techniques and procedures. Unpublished data of the U.S. Geological Survey on sample collection are briefly cited also.

  9. Fluoroscopically Guided Interventional Procedures: A Review of Radiation Effects on Patients’ Skin and Hair

    DTIC Science & Technology

    2010-02-01

    subsequent research has yielded additional in- sights. This review is a consensus report of current scien- tifi c data. Expected skin reactions for an...table has been cited and reproduced Essentials The minimum radiation dose n causing a specifi c type of reac- tion in the skin or hair is best...expressed in terms of a range of doses, rather than a single threshold dose. The times of onset and resolution n of specifi c radiation injuries

  10. Empty Offices.

    ERIC Educational Resources Information Center

    Cunningham, William G.; Burdick, Glenn R.

    1999-01-01

    Survey responses from 175 public school superintendents blamed school boards for the dwindling supply of qualified applicants for the superintendency. The top problem is micromanagement by the school board. The time and stress of the superintendency ranks second, cited by more than 53 percent of respondents. Diminishing financial resources were…

  11. Yeast: An Experimental Organism for Modern Biology.

    ERIC Educational Resources Information Center

    Botstein, David; Fink, Gerald R.

    1988-01-01

    Discusses the applicability and advantages of using yeasts as popular and ideal model systems for studying and understanding eukaryotic biology at the cellular and molecular levels. Cites experimental tractability and the cooperative tradition of the research community of yeast biologists as reasons for this success. (RT)

  12. What's So Hard about Understanding Language?

    ERIC Educational Resources Information Center

    Read, Walter; And Others

    A discussion of the application of artificial intelligence to natural language processing looks at several problems in language comprehension, involving semantic ambiguity, anaphoric reference, and metonymy. Examples of these problems are cited, and the importance of the computational approach in analyzing them is explained. The approach applies…

  13. Sludge.

    ERIC Educational Resources Information Center

    Tenenbaum, David

    1992-01-01

    Cites a recycling success story involving sludge production from wastewater and transformation into an effective plant fertilizer. Discusses related concerns such as dealing with pollutants like heavy metals and PCBs often found in sludge. Provides an example of an application of sludge produced in Chicago to an area reclamation site. (MCO)

  14. Marijuana: Modern Medical Chimaera

    ERIC Educational Resources Information Center

    Lamarine, Roland J.

    2012-01-01

    Marijuana has been used medically since antiquity. In recent years there has been a resurgence of interest in medical applications of various cannabis preparations. These drugs have been cited in the medical literature as potential secondary treatment agents for severe pain, muscle spasticity, anorexia, nausea, sleep disturbances, and numerous…

  15. Challenges and complications in neighborhood mapping: from neighborhood concept to operationalization

    NASA Astrophysics Data System (ADS)

    Deng, Yongxin

    2016-07-01

    This paper examines complications in neighborhood mapping and corresponding challenges for the GIS community, taking both a conceptual and a methodological perspective. It focuses on the social and spatial dimensions of the neighborhood concept and highlights their relationship in neighborhood mapping. Following a brief summary of neighborhood definitions, five interwoven factors are identified to be origins of neighborhood mapping difficulties: conceptual vagueness, uncertainty of various sources, GIS representation, scale, and neighborhood homogeneity or continuity. Existing neighborhood mapping methods are grouped into six categories to be assessed: perception based, physically based, inference based, preexisting, aggregated, and automated. Mapping practices in various neighborhood-related disciplines and applications are cited as examples to demonstrate how the methods work, as well as how they should be evaluated. A few mapping strategies for the improvement of neighborhood mapping are prescribed from a GIS perspective: documenting simplifications employed in the mapping procedure, addressing uncertainty sources, developing new data solutions, and integrating complementary mapping methods. Incorporation of high-resolution data and introduction of more GIS ideas and methods (such as fuzzy logic) are identified to be future opportunities.

  16. An innovative validated spectrofluorimetric method for determination of Lisinopril in presence of hydrochlorothiazide; application to content uniformity testing

    NASA Astrophysics Data System (ADS)

    Derayea, Sayed M.; Badr El-din, Khalid M.; Mohammed, Fatma F.

    2018-01-01

    A new sensitive and discriminating spectrofluorimetric method has been developed and validated for determination of Lisinopril, one of the angiotensin converting enzyme inhibitors, in its pure bulk form and pharmaceutical tablets. The reaction of Lisinopril with ethylacetoacetate and formaldehyde in acidic buffered medium (pH 3.8) has yielded a pale yellow product that exhibited a high fluorescence measured at 438 nm after excitation at 350 nm. All the experimental parameters affecting the formation and stability of the produced fluorophore were carefully investigated and optimized to give the maximum sensitivity. The fluorescence intensity was directly proportional to the drug concentration in the range of 0.5-4.5 μg/mL with a limit of detection equal to 0.16 μg/mL. The method was successfully applied in the analysis of the commercially available pharmaceutical tablets containing the single drug or its binary mixtures with Hydrochlorothiazide. Furthermore, the developed procedure was adapted for studying the content uniformity test of some dosage forms containing the cited drug.

  17. Species-area relationships and extinction forecasts.

    PubMed

    Halley, John M; Sgardeli, Vasiliki; Monokrousos, Nikolaos

    2013-05-01

    The species-area relationship (SAR) predicts that smaller areas contain fewer species. This is the basis of the SAR method that has been used to forecast large numbers of species committed to extinction every year due to deforestation. The method has a number of issues that must be handled with care to avoid error. These include the functional form of the SAR, the choice of equation parameters, the sampling procedure used, extinction debt, and forest regeneration. Concerns about the accuracy of the SAR technique often cite errors not much larger than the natural scatter of the SAR itself. Such errors do not undermine the credibility of forecasts predicting large numbers of extinctions, although they may be a serious obstacle in other SAR applications. Very large errors can arise from misinterpretation of extinction debt, inappropriate functional form, and ignoring forest regeneration. Major challenges remain to understand better the relationship between sampling protocol and the functional form of SARs and the dynamics of relaxation, especially in continental areas, and to widen the testing of extinction forecasts. © 2013 New York Academy of Sciences.

  18. Top-Cited Articles in Problem-Based Learning: A Bibliometric Analysis and Quality of Evidence Assessment.

    PubMed

    Azer, Samy A

    2017-04-01

    The aims of this study were to identify characteristics of the top-cited articles in problem-based learning (PBL) and assess the quality of evidence provided by these articles. The most frequently cited articles on PBL were searched in April 2015 in the Science Citation Index Expanded database (List A) and Google Scholar database (List B). Eligible articles identified were reviewed for key characteristics. The Oxford Centre for Evidence-Based Medicine guidelines were used in assessing the level of evidence. The number of citations varied (62 to 923 on List A and 218 to 2,859 on List B). Countries that contributed the majority of articles in both lists were the United States, Netherlands, United Kingdom, and Canada. No significant correlations were found between number of citations and number of years since published (p=0.451), number of authors (p=0.144), females in authorship (p=0.189), non-medical authors (p=0.869), number of institutions (p=0.452), and number of grants (p=0.143), but a strong correlation was found with number of countries involved (p=0.007). Application of the Oxford hierarchy of evidence showed that 36 articles were at levels 4 and 5 of evidence. This study found that research articles represented approximately one-third of PBL articles assessed and reported mainly on questionnaire-based studies. The most highly cited articles occupied top-ranking positions in the journals in which they were published. The lower level of evidence observed in most top-cited articles may reflect the significance of innovative ideas or content of these articles. These findings have implications for dental educators and dental researchers.

  19. Visualization of evidence-based medicine domain knowledge: production and citation of Cochrane systematic reviews.

    PubMed

    Shen, Jiantong; Li, Youping; Clarke, Mike; Du, Liang; Wang, Li; Zhong, Dake

    2013-02-01

    To evaluate the production and utilization of Cochrane systematic reviews (CSRs) and to analyze its influential factors, so as to improve the capacity of translating CSRs into practice. All CSRs and protocols were retrieved from the Cochrane Library (Issue 2, 2011) and citation data were retrieved from SCI database. Citation analysis was used to analyze the situation of CSRs production and utilization. CSR publication had grown from an annual average of 32 to 718 documents. Only one developing country was among the ten countries with the largest amount of publications. High-income countries accounted for 83% of CSR publications and 90.8% of cited counts. A total 34.7% of CSRs had a cited count of 0, whereas only 0.9% had been cited more than 50 times. Highly cited CSRs were published in England, Australia, Canada, USA and other high-income countries. The countries with a Cochrane center or a Cochrane methodology group had a greater capability of CSRs production and citing than others. The CSRs addressing the topics of diseases were more than those targeted at public health issues. There was a big gap in citations of different interventions even on the same topic. The capability of CSR production and utilization grew rapidly, but varied among countries and institutions, which was affected by several factors such as the capability of research, resources and the applicability of evidence. It is important to improve evidence translation through educating, training and prioritizing the problems based on real demands of end users. © 2013 Wiley Publishing Asia Pty Ltd and Chinese Cochrane Center, West China Hospital of Sichuan University.

  20. Airborne observations of newly formed boundary layer aerosol particles under cloudy conditions

    NASA Astrophysics Data System (ADS)

    Altstädter, Barbara; Platis, Andreas; Jähn, Michael; Baars, Holger; Lückerath, Janine; Held, Andreas; Lampert, Astrid; Bange, Jens; Hermann, Markus; Wehner, Birgit

    2018-06-01

    This study describes the appearance of ultrafine boundary layer aerosol particles under classical non-favourable conditions at the research site of TROPOS (Leibniz Institute for Tropospheric Research). Airborne measurements of meteorological and aerosol properties of the atmospheric boundary layer (ABL) were repeatedly performed with the unmanned aerial system ALADINA (Application of Light-weight Aircraft for Detecting IN-situ Aerosol) during three seasons between October 2013 and July 2015. More than 100 measurement flights were conducted on 23 different days with a total flight duration of 53 h. In 26 % of the cases, maxima of ultrafine particles were observed close to the inversion layer at altitudes between 400 and 600 m and the particles were rapidly mixed vertically and mainly transported downwards during short time intervals of cloud gaps. This study focuses on two measurement days affected by low-level stratocumulus clouds, but different wind directions (NE, SW) and minimal concentrations (< 4.6 µg m-3) of SO2, as a common indicator for precursor gases at ground. Taken from vertical profiles, the onset of clouds led to a non-linearity of humidity that resulted in an increased turbulence at the local-scale and caused fast nucleation e.g., but in relation to rapid dilution of surrounding air, seen in sporadic clusters of ground data, so that ultrafine particles disappeared in the verticality. The typical banana shape of new particle formation (NPF) and growth was not seen at ground and thus these days might not have been classified as NPF event days by pure surface studies.

  1. NASA patent abstracts bibliography: A continuing bibliography. Section 1: Abstracts (supplement 13)

    NASA Technical Reports Server (NTRS)

    1978-01-01

    This bibliography is issued in two sections: Section 1 - Abstracts, and Section 2 - Indexes. This issue of the Abstract Section cites 161 patents and applications for patent introduced into the NASA scientific and technical information system during the period January 1978 through June 1978. Each entry consists of a citation, an abstract, and in most cases, a key illustration selected from the patent or application for patent.

  2. An Introduction to the National Crime Survey. Applications of the National Crime Survey Victimization and Attitude Data, Analytic Report SD-VAD-4.

    ERIC Educational Resources Information Center

    Garofalo, James; Hindelang, Michael J.

    The purpose of the document is to identify ways in which National Crime Survey (NCS) data can be used by criminal justice researchers and programs. The report provides an overview of the Application of Victimization Survey Results Project, describes the analytic reports compiled by the project staff, and cites the kinds of systematic information…

  3. Continuously variable transmission: Assessment of applicability to advance electric vehicles

    NASA Technical Reports Server (NTRS)

    Loewenthal, S. H.; Parker, R. J.

    1981-01-01

    A brief historical account of the evolution of continuously variable transmissions (CVT) for automotive use is given. The CVT concepts which are potentially suitable for application with electric and hybrid vehicles are discussed. The arrangement and function of several CVT concepts are cited along with their current developmental status. The results of preliminary design studies conducted on four CVT concepts for use in advanced electric vehicles are discussed.

  4. SU-E-I-98: PET/CT's Most-Cited 50 Articles since 2000: A Bibliometric Analysis of Classics.

    PubMed

    Sayed, G

    2012-06-01

    Despite its relatively recent introduction to clinical practice, PET/CT has gained wide acceptance both in diagnostic and therapeutic applications. Scientific publication in PET/CT has also experienced significant development since its introduction. Bibliometric analyses allow an understanding of how this publication trend has developed at an aggregated level. Citation analysis is one of the most widely used bibliometric tools of scientometrics. Analysis of classics, defined as an articles with 100 or more citations, is common in the biomedical sciences as it reflects an article's influence in its professional and scientific community. Our objective was to identify the 50 most frequently cited classic articles in PET/CT in the past 10 years. The 50 most-cited PET/CT articles were identified by searching ISI's Web of Knowledge and Pubmed databases for all related publications from 2000 through 2010. Articles were evaluated for several characteristics such as author(s), institution, country of origin, publication year, type, and number of citations. An unadjusted categorical analysis was performed to compare all articles published in the search period. The search yielded a cumulative total of 22,554 entries for the publication period, of which 15,943 were original research articles. The 50 most-cited articles were identified from the latter sum and selected out of 73 classics. The number of citations for the top 50 classics ranged from 114 to 700. PET/CT classics appeared in three general and 12 core journals. The majority of the classics were in oncologic applications of PET/CT (62%). Articles related to diagnostic topics were 6%. The rest were focused on physics and instrumentation 24% and other basic sciences 16%. Despite its relatively short history PET/CT accumulated 73 classic articles in a decade. Such information is of importance to researchers and those who wish to study the scientific development in the field. © 2012 American Association of Physicists in Medicine.

  5. Do scientific advancements lean on the shoulders of giants? A bibliometric investigation of the Ortega hypothesis.

    PubMed

    Bornmann, Lutz; de Moya Anegón, Félix; Leydesdorff, Loet

    2010-10-13

    In contrast to Newton's well-known aphorism that he had been able "to see further only by standing on the shoulders of giants," one attributes to the Spanish philosopher Ortega y Gasset the hypothesis saying that top-level research cannot be successful without a mass of medium researchers on which the top rests comparable to an iceberg. The Ortega hypothesis predicts that highly-cited papers and medium-cited (or lowly-cited) papers would equally refer to papers with a medium impact. The Newton hypothesis would be supported if the top-level research more frequently cites previously highly-cited work than that medium-level research cites highly-cited work. Our analysis is based on (i) all articles and proceedings papers which were published in 2003 in the life sciences, health sciences, physical sciences, and social sciences, and (ii) all articles and proceeding papers which were cited within these publications. The results show that highly-cited work in all scientific fields more frequently cites previously highly-cited papers than that medium-cited work cites highly-cited work. We demonstrate that papers contributing to the scientific progress in a field lean to a larger extent on previously important contributions than papers contributing little. These findings support the Newton hypothesis and call into question the Ortega hypothesis (given our usage of citation counts as a proxy for impact).

  6. 40 CFR 272.2501 - Wisconsin State-administered program; final authorization.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... (CONTINUED) SOLID WASTES (CONTINUED) APPROVED STATE HAZARDOUS WASTE MANAGEMENT PROGRAMS Wisconsin § 272.2501... cited in this paragraph are incorporated by reference as part of the hazardous waste management program... Applicable to the Hazardous Waste Management Program, (dated August 9, 1993). (2) EPA Approved Wisconsin...

  7. Analysis of Orthopaedic Research Produced During the Wars in Iraq and Afghanistan.

    PubMed

    Balazs, George C; Dickens, Jonathan F; Brelin, Alaina M; Wolfe, Jared A; Rue, John-Paul H; Potter, Benjamin K

    2015-09-01

    Military orthopaedic surgeons have published a substantial amount of original research based on our care of combat-wounded service members and related studies during the wars in Iraq and Afghanistan. However, to our knowledge, the influence of this body of work has not been evaluated bibliometrically, and doing so is important to determine the modern impact of combat casualty research in the wider medical community. We sought to identify the 20 most commonly cited works from military surgeons published during the Iraq and Afghanistan conflicts and analyze them to answer the following questions: (1) What were the subject areas of these 20 articles and what was the 2013 Impact Factor of each journal that published them? (2) How many citations did they receive and what were the characteristics of the journals that cited them? (3) Do the citation analysis results obtained from Google Scholar mirror the results obtained from Thompson-Reuters' Web of Science? We searched the Web of Science Citation Index Expanded for relevant original research performed by US military orthopaedic surgeons related to Operation Iraqi Freedom and Operation Enduring Freedom between 2001 and 2014. Articles citing these studies were reviewed using both Web of Science and Google Scholar data. The 20 most cited articles meeting inclusion criteria were identified and analyzed by content domain, frequency of citation, and sources in which they were cited. Nine of these studies examined the epidemiology and outcome of combat injury. Six studies dealt with wound management, wound dehiscence, and formation of heterotopic ossification. Five studies examined infectious complications of combat trauma. The median number of citations garnered by these 20 articles was 41 (range, 28-264) in Web of Science. Other research citing these studies has appeared in 279 different journals, covering 26 different medical and surgical subspecialties, from authors in 31 different countries. Google Scholar contained 97% of the Web of Science citations, but also had 31 duplicate entries and 29 citations with defective links. Modern combat casualty research by military orthopaedic surgeons is widely cited by researchers in a diverse range of subspecialties and geographic locales. This suggests that the military continues to be a source of innovation that is broadly applicable to civilian medical and surgical practice and should encourage expansion of military-civilian collaboration to maximize the utility of the knowledge gained in the treatment of war trauma. Level IV, therapeutic study.

  8. Predicting actual weight loss: A review of the determinants according to the theory of planned behaviour

    PubMed Central

    Fong, Shirley Siu Ming

    2015-01-01

    Weight reduction that corresponds with lifestyle modification is difficult to foster. The theory of planned behaviour has been actively cited in explaining health-related behaviour. This review evaluated the application of the theory of planned behaviour to weight-loss behaviour. Among the three reviewed papers, cross-sectional survey designs and subjective outcome measurements were commonly applied. All of the studies recruited obese female adults as participants, limiting the generalisability of the studies’ findings. The theory of planned behaviour can be effectively applied in weight-reduction programmes targeting female obese patients. This review confirmed critiques citing the limitations of experimental studies, the subjective measurement of behaviour and short follow-up periods. PMID:28070350

  9. Wilms' tumorigenesis is altered by misexpression of the transcriptional co-activator, CITED1

    PubMed Central

    Lovvorn, Harold N.; Boyle, Scott; Shi, Genbin; Shyr, Yu; Wills, Marcia L.; Perantoni, Alan O.; de Caestecker, Mark

    2011-01-01

    Purpose Wilms' tumors arise from arrested differentiation of renal progenitor cells. CITED1 is a transcriptional regulator that blocks the metanephric mesenchymal-to-epithelial conversion and is expressed in the blastema of both the developing kidney and Wilms' tumors. We hypothesized that alterations of CITED1-dependent signaling promote persistence of blastema and thereby subject these pluripotent cells to future oncogenic events. Methods We used a retroviral delivery system to overexpress the full-length CITED1 (F/L) protein and 2 deletion mutants lacking either of its known functional domains, ΔSID (Smad-4 Interacting Domain) and ΔCR2 (Conserved Region 2; the CITED1 transactivation domain), in a human Wilms' tumor cell line that endogenously expresses CITED1. In vitro effects on cellular proliferation and apoptosis were assayed. In vivo effects on tumorigenesis, growth, proliferation, and apoptosis were determined after heterotransplantation into immunodeficient mice (n = 15 per cell line). Results In vitro, overexpression of CITED1-F/L significantly increased, whereas overexpression of the functionally inactivating mutant, CITED1-ΔCR2, significantly reduced cellular proliferation relative to the other lines ( P <.0001). In vivo, Wilms' tumor incidence was significantly reduced in animals injected with cells overexpressing the mutant CITED1-ΔCR2 (7%) compared with CITED1-F/L (40%, P = .03) and CITED1-ΔSID (60%, P < .002). Similarly, mean tumor volume was least in the CITED1-ΔCR2 animals when compared with CITED1-F/L ( P = .03) and CITED1-ΔSID animals ( P <.005). Furthermore, the CITED1-ΔCR2 tumor showed the least cellular proliferation. Misexpression of CITED1 did not affect apoptosis either in vitro or in vivo. Conclusions Overexpression of CITED1 in a human Wilms' tumor cell line significantly increases proliferation in vitro, whereas mutation of its functionally critical transactivation domain (ΔCR2) significantly reduces proliferation. This mutation further perturbs tumorigenesis and tumor growth after heterotransplantation into immunodeficient mice. We speculate that overexpression of CITED1 promotes expansion of a rapidly proliferating population of blastema and thereby induces an unstable environment highly susceptible to future oncogenic events. PMID:17336183

  10. Space benefits: The secondary application of aerospace technology in other sectors of the economy

    NASA Technical Reports Server (NTRS)

    1976-01-01

    A benefits briefing notebook is presented for the NASA Technology Utilization Office in which 515 applications of NASA aerospace technology to other sections of the economy are described. An overview of technology transfer is given. Benefit cases are cited in 19 categories along with pertinent information, such as communication link, DRI transfer example file, and individual case number. General, organization, geographic, and field center indexes are provided.

  11. Translations on Eastern Europe Political, Sociological, and Military Affairs, Number 1364

    DTIC Science & Technology

    1977-03-14

    Springfield, Virginia 22151. In order- ing, it is recommended that the JPRS number, title, date and author, if applicable , of publication be cited...minister of supply and state reserves issues instructions on settl- ing questions arising over the application of the decree. §3. Point 3 of the Directive...suffocating action and irritates the eyes. In using water to contain the spread of a chlorine cloud, the chlorine forms hydrochloric and hypochlorous

  12. Cited1 Deficiency Suppresses Intestinal Tumorigenesis

    PubMed Central

    Young, Madeleine; Poetz, Oliver; Parry, Lee; Jenkins, John R.; Williams, Geraint T.; Dunwoodie, Sally L.; Watson, Alastair; Clarke, Alan R.

    2013-01-01

    Conditional deletion of Apc in the murine intestine alters crypt-villus architecture and function. This process is accompanied by multiple changes in gene expression, including upregulation of Cited1, whose role in colorectal carcinogenesis is unknown. Here we explore the relevance of Cited1 to intestinal tumorigenesis. We crossed Cited1 null mice with ApcMin/+ and AhCre+Apcfl/fl mice and determined the impact of Cited1 deficiency on tumour growth/initiation including tumour multiplicity, cell proliferation, apoptosis and the transcriptome. We show that Cited1 is up-regulated in both human and murine tumours, and that constitutive deficiency of Cited1 increases survival in ApcMin/+ mice from 230.5 to 515 days. However, paradoxically, Cited1 deficiency accentuated nearly all aspects of the immediate phenotype 4 days after conditional deletion of Apc, including an increase in cell death and enhanced perturbation of differentiation, including of the stem cell compartment. Transcriptome analysis revealed multiple pathway changes, including p53, PI3K and Wnt. The activation of Wnt through Cited1 deficiency correlated with increased transcription of β-catenin and increased levels of dephosphorylated β-catenin. Hence, immediately following deletion of Apc, Cited1 normally restrains the Wnt pathway at the level of β-catenin. Thus deficiency of Cited1 leads to hyper-activation of Wnt signaling and an exaggerated Wnt phenotype including elevated cell death. Cited1 deficiency decreases intestinal tumourigenesis in ApcMin/+ mice and impacts upon a number of oncogenic signaling pathways, including Wnt. This restraint imposed by Cited1 is consistent with a requirement for Cited1 to constrain Wnt activity to a level commensurate with optimal adenoma formation and maintenance, and provides one mechanism for tumour repression in the absence of Cited1. PMID:23935526

  13. Poorly cited articles in peer-reviewed cardiovascular journals from 1997 to 2007: analysis of 5-year citation rates.

    PubMed

    Ranasinghe, Isuru; Shojaee, Abbas; Bikdeli, Behnood; Gupta, Aakriti; Chen, Ruijun; Ross, Joseph S; Masoudi, Frederick A; Spertus, John A; Nallamothu, Brahmajee K; Krumholz, Harlan M

    2015-05-19

    The extent to which articles are cited is a surrogate of the impact and importance of the research conducted; poorly cited articles may identify research of limited use and potential wasted investments. We assessed trends in the rates of poorly cited articles and journals in the cardiovascular literature from 1997 to 2007. We identified original articles published in cardiovascular journals and indexed in the Scopus citation database from 1997 to 2007. We defined poorly cited articles as those with ≤5 citations in the 5 years following publication and poorly cited journals as those with >75% of journal content poorly cited. We identified 164 377 articles in 222 cardiovascular journals from 1997 to 2007. From 1997 to 2007, the number of cardiovascular articles and journals increased by 56.9% and 75.2%, respectively. Of all the articles, 75 550 (46.0%) were poorly cited, of which 25 650 (15.6% overall) had no citations. From 1997 to 2007, the proportion of poorly cited articles declined slightly (52.1%-46.2%, trend P<0.001), although the absolute number of poorly cited articles increased by 2595 (trend P<0.001). At a journal level, 44% of cardiovascular journals had more than three-fourths of the journal's content poorly cited at 5 years. Nearly half of all peer-reviewed articles published in cardiovascular journals are poorly cited 5 years after publication, and many are not cited at all. The cardiovascular literature and the number of poorly cited articles both increased substantially from 1997 to 2007. The high proportion of poorly cited articles and journals suggests inefficiencies in the cardiovascular research enterprise. © 2015 American Heart Association, Inc.

  14. Poorly Cited Articles in Peer-Reviewed Cardiovascular Journals from 1997–2007: Analysis of 5-Year Citation Rates

    PubMed Central

    Ranasinghe, Isuru; Shojaee, Abbas; Bikdeli, Behnood; Gupta, Aakriti; Chen, Ruijun; Ross, Joseph S.; Masoudi, Frederick; Spertus, John A.; Nallamothu, Brahmajee K.; Krumholz, Harlan M.

    2015-01-01

    Background The extent to which articles are cited is a surrogate of the impact and importance of the research conducted; poorly cited papers may identify research of limited use and potential wasted investments. We assessed trends in the rates of poorly cited articles and journals in the cardiovascular literature from 1997–2007. Methods and Results We identified original articles published in cardiovascular journals and indexed in the Scopus citation database from 1997–2007. We defined poorly cited articles as those with ≤5 citations in the 5 years following publication and poorly cited journals as those with >75% of journal content poorly cited. We identified 164,377 articles in 222 cardiovascular journals from 1997–2007. From 1997–2007, the number of cardiovascular articles and journals increased by 56.9% and 75.2% respectively. Of all the articles, 75,550 (46.0%) were poorly cited, of which 25,650 (15.6% overall) had no citations. From 1997–2007, the proportion of poorly cited articles declined slightly (52.1% to 46.2%, trend P<0.001), although the absolute number of poorly cited articles increased by 2,595 (trend P<0.001). At a journal level, 44% of cardiovascular journals had more than three quarters of the journal’s content poorly cited at 5 years. Conclusion Nearly half of all peer-reviewed articles published in cardiovascular journals are poorly cited 5 years after publication, and many are not cited at all. The cardiovascular literature, and the number of poorly cited articles, have both increased substantially from 1997–2007. The high proportion of poorly cited articles and journals suggest inefficiencies in the cardiovascular research enterprise. PMID:25812573

  15. 43 CFR 12.51 - State plans.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Lands: Interior Office of the Secretary of the Interior ADMINISTRATIVE AND AUDIT REQUIREMENTS AND COST...) Assurances. In each plan the State will include an assurance that the State shall comply with all applicable.... For this assurance and other assurances required in the plan, the State may: (1) Cite by number the...

  16. 75 FR 80011 - Good Laboratory Practice for Nonclinical Laboratory Studies

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-21

    ... for research or marketing permits for products regulated by FDA, including food and color additives, animal food additives, human and animal drugs, medical devices for human use, biological products, and... requested the ability to cite compliance with the applicable good manufacturing requirements (i.e, parts 210...

  17. Research Methods in the Behavioral Sciences: A Selected Bibliography. Exchange Bibliography No. 639.

    ERIC Educational Resources Information Center

    McFarland, Dalton E.

    This bibliography lists publications dealing with research methodologies in the behavioral sciences of psychology, sociology, anthropology, and social psychology. Few of the works deal directly with research methods in economics, history, business administration, or education. Most of the books cited cover a variety of applicable research…

  18. Something so Right

    ERIC Educational Resources Information Center

    Emery, Jill

    2010-01-01

    In August 2010, "Wired" magazine declared, "The Web is Dead. Long Live the Internet." Citing the rise of IPad & Smartphone sales and the rapid explosion of application-based software to run various programs on multiple computing devices--but especially mobile computing devices--people spend more hours than ever connected to or "on" the Internet…

  19. 48 CFR 1852.245-70 - Contractor requests for Government-owned equipment.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... the equipment and the reasons why contractor-owned property cannot be used, citing the applicable FAR... 1419, DOD Industrial Plant Equipment Requisition, or equivalent format, for each item requested and (ii... Government-owned equipment. 1852.245-70 Section 1852.245-70 Federal Acquisition Regulations System NATIONAL...

  20. Improving Programs and Outcomes: Implementation Frameworks and Organization Change

    ERIC Educational Resources Information Center

    Bertram, Rosalyn M.; Blase, Karen A.; Fixsen, Dean L.

    2015-01-01

    This article presents recent refinements to implementation constructs and frameworks. It updates and clarifies the frequently cited study conducted by the National Implementation Research Network that introduced these frameworks for application in diverse endeavors. As such, it may serve as a historical marker in the rapidly developing science and…

  1. 7 CFR 3405.11 - Content of a proposal.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... authorized organizational representative for the applicant institution. (3) The title of the project shown on... peer panel meeting. The name of the institution, the targeted need area(s), and the title of the... identify the other complementary project(s) by citing the name of the submitting institution, the title of...

  2. Heat pipe technology. A bibliography with abstracts

    NASA Technical Reports Server (NTRS)

    1978-01-01

    This bibliography cites 55 publications on the theory, design, development, fabrication, and testing of heat pipes. Applications covered include solar, nuclear, and thermoelectric energy conversion. A book (in Russian) on low temperature heat pipes is included as well as abstracts when available. Indexes provided list authors, titles/keywords (permuted) and patents.

  3. Social Sciences in Forestry. A Current Selected Bibliography and Index. No. 73.

    ERIC Educational Resources Information Center

    Albrecht, Jean, Ed.; Rodkewich, Patricia, Ed.

    1987-01-01

    This issue of "Social Sciences in Forestry" provides an annotated bibliographic listing of 660 current references arranged according to four major areas of forestry: (1) applications to forestry at large (containing citings on resources, history, legislation, policy, planning, appraisal and valuation, investment and finance, taxation,…

  4. Social Sciences in Forestry. A Current Selected Bibliography and Index. No. 70.

    ERIC Educational Resources Information Center

    Albrecht, Jean, Ed.; Rodkewich, Patricia, Ed.

    1987-01-01

    This issue of "Social Sciences in Forestry" provides an annotated bibliographic listing of 592 current references arranged according to four major areas of forestry: (1) applications to forestry at large (containing citings on resources, history, legislation, policy, planning, appraisal and valuation, investment and finance, taxation,…

  5. Superposition: New Solutions from Known Solutions

    ERIC Educational Resources Information Center

    Roberts, Charles E.

    2003-01-01

    This note contains material to be presented to students in a first course in differential equations immediately after they have completed studying first-order differential equations and their applications. The purpose of presenting this material is four-fold: to review definitions studied previously; to provide a historical context which cites the…

  6. 38 CFR 59.50 - Priority list.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... systems or features is necessary to remedy a cited threat to the lives or safety of residents and program... utility systems or features; such applications will be prioritized in accordance with the criteria in...) All other projects (e.g., nurse call systems, patient lifts). (ii) Priority group 1—subpriority 2. An...

  7. 38 CFR 59.50 - Priority list.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... systems or features is necessary to remedy a cited threat to the lives or safety of residents and program... utility systems or features; such applications will be prioritized in accordance with the criteria in...) All other projects (e.g., nurse call systems, patient lifts). (ii) Priority group 1—subpriority 2. An...

  8. Applications of Artificial Intelligence in Education--A Personal View.

    ERIC Educational Resources Information Center

    Richer, Mark H.

    1985-01-01

    Discusses: how artificial intelligence (AI) can advance education; if the future of software lies in AI; the roots of intelligent computer-assisted instruction; protocol analysis; reactive environments; LOGO programming language; student modeling and coaching; and knowledge-based instructional programs. Numerous examples of AI programs are cited.…

  9. 48 CFR 306.304 - Approval of the justification.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... justification. 306.304 Section 306.304 Federal Acquisition Regulations System HEALTH AND HUMAN SERVICES COMPETITION AND ACQUISITION PLANNING COMPETITION REQUIREMENTS Other Than Full and Open Competition 306.304... acquisitions in the dollar amount cited in FAR 6.304(a)(2) through (a)(4), the CCO, if applicable, and the HCA...

  10. Information Resources on Microcomputers in Libraries: Public Services. A Selected ERIC Bibliography.

    ERIC Educational Resources Information Center

    ERIC Clearinghouse on Information Resources, Syracuse, NY.

    Twelve articles published between 1982 and 1984 and cited in "Current Index to Journals in Education" are listed in this bibliography on public service applications of microcomputers in libraries. Topics include provision of free public access to microcomputers (justification, objectives, equipment specifications, uses and software,…

  11. 21 CFR 299.4 - Established names for drugs.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... organization sponsored by the American Medical Association, the United States Pharmacopeia, and the American... proposed in the application that meets the above-cited guidelines. Prior use of a name in the medical literature or otherwise will not commit the Food and Drug Administration to adopting such terminology as...

  12. Earth Matters: Studies for Our Global Future.

    ERIC Educational Resources Information Center

    Wasserman, Pamela; Doyle, Andrea

    Through 12 readings and 32 activities this curriculum material introduces high school students to issues of the global environment and society, while both challenging them to critically evaluate the issues and motivating them to develop solutions. The materials are cited as being applicable to social studies, science, math, language arts, and…

  13. Effects on fish and wildlife of chemical treatments of large areas

    USGS Publications Warehouse

    George, J.L.

    1959-01-01

    Summary: The history of field investigations of the effects of DDT on wildlife is reviewed briefly, from the initial studies in 1945 through the more recent studies of the effects of the large-scale programs for spruce-budworm control and gypsy-moth eradication. DDT dosages and procedures that are recommended for protection of wildlife are reviewed. Effects of aldrin, heptachlor, and toxaphene are discussed in connection with the grasshopper and Mormon cricket control programs. Delayed and indirect effects of chemical treatments are emphasized as an important current problem. Cited in this connection are fish losses in the Yellowstone and Miramichi rivers and losses of wildlife from eating earthworms a year after treatment of the area with DDT. Currently recommended procedures to safeguard wildlife in pesticidal programs are listed.

  14. The Impact of 10 Years of War on Combat Casualty Care Research: A Citation Analysis

    DTIC Science & Technology

    2012-01-01

    2004 74 14 Alam HB, Chen Z, Jaskille A, et al. Application of a zeolite hemostatic agent achieves 100% survival in a lethal model of complex groin...Among the preclinical studies, the most cited was #14 by Alam et al. (2004), ‘‘Application of a zeolite hemostatic agent achieves 100% survival in a...patients. J Trauma. 2006;60:363Y370. 2006 44 47 Wright JK, Kalns J, Wolf EA, et al. Thermal injury resulting from application of a granular mineral

  15. [Research progress on the clinical value of Ki-67 in breast cancer and its cut-off definition].

    PubMed

    Chen, Qing; Wu, Kejin

    2015-08-01

    Ki-67 has an important application value in clinical practice. However, it is still a little tough in clinical application because of the debate on the cut-off definition of Ki-67 index. This review summarizes most studies on the prognostic and predictive value of Ki-67, analyzes the reasons for the discrepancies among the studies cited, and presents the necessity and clinical significance of scientifically defining the cut-off of Ki-67 index, providing a theoretical basis for Ki-67 in clinical application.

  16. Optical imaging probes in oncology

    PubMed Central

    Martelli, Cristina; Dico, Alessia Lo; Diceglie, Cecilia; Lucignani, Giovanni; Ottobrini, Luisa

    2016-01-01

    Cancer is a complex disease, characterized by alteration of different physiological molecular processes and cellular features. Keeping this in mind, the possibility of early identification and detection of specific tumor biomarkers by non-invasive approaches could improve early diagnosis and patient management. Different molecular imaging procedures provide powerful tools for detection and non-invasive characterization of oncological lesions. Clinical studies are mainly based on the use of computed tomography, nuclear-based imaging techniques and magnetic resonance imaging. Preclinical imaging in small animal models entails the use of dedicated instruments, and beyond the already cited imaging techniques, it includes also optical imaging studies. Optical imaging strategies are based on the use of luminescent or fluorescent reporter genes or injectable fluorescent or luminescent probes that provide the possibility to study tumor features even by means of fluorescence and luminescence imaging. Currently, most of these probes are used only in animal models, but the possibility of applying some of them also in the clinics is under evaluation. The importance of tumor imaging, the ease of use of optical imaging instruments, the commercial availability of a wide range of probes as well as the continuous description of newly developed probes, demonstrate the significance of these applications. The aim of this review is providing a complete description of the possible optical imaging procedures available for the non-invasive assessment of tumor features in oncological murine models. In particular, the characteristics of both commercially available and newly developed probes will be outlined and discussed. PMID:27145373

  17. Claims for fertility interventions: a systematic assessment of statements on UK fertility centre websites

    PubMed Central

    Spencer, E A; Mahtani, K R; Goldacre, B; Heneghan, C

    2016-01-01

    Objectives Fertility services in the UK are offered by over 200 Human Fertilisation and Embryology Authority (HFEA)-registered NHS and private clinics. While in vitro fertilisation (IVF) and intracytoplasmic sperm injection (ICSI) form part of the National Institute for Health and Care Excellence (NICE) guidance, many further interventions are offered. We aimed to record claims of benefit for interventions offered by fertility centres via information on the centres' websites and record what evidence was cited for these claims. Methods We obtained from HFEA a list of all UK centres providing fertility treatments and examined their websites. We listed fertility interventions offered in addition to standard IVF and ICSI and recorded statements about interventions that claimed or implied improvements in fertility in healthy women. We recorded which claims were quantified, and the evidence cited in support of the claims. Two reviewers extracted data from websites. We accessed websites from 21 December 2015 to 31 March 2016. Results We found 233 websites for HFEA-registered fertility treatment centres, of which 152 (65%) were excluded as duplicates or satellite centres, 2 were andrology clinics and 5 were unavailable or under construction websites. In total, 74 fertility centre websites, incorporating 1401 web pages, were examined for claims. We found 276 claims of benefit relating to 41 different fertility interventions made by 60 of the 74 centres (median 3 per website; range 0 to 10). Quantification was given for 79 (29%) of the claims. 16 published references were cited 21 times on 13 of the 74 websites. Conclusions Many fertility centres in the UK offer a range of treatments in addition to standard IVF procedures, and for many of these interventions claims of benefit are made. In most cases, the claims are not quantified and evidence is not cited to support the claims. There is a need for more information on interventions to be made available by fertility centres, to support well-informed treatment decisions. PMID:27890866

  18. Trends in clinical reproductive medicine research: 10 years of growth.

    PubMed

    Aleixandre-Benavent, Rafael; Simon, Carlos; Fauser, Bart C J M

    2015-07-01

    To study the most important metrics of publication in the field of reproductive medicine over the decade 2003-2012 to aid in discerning the clinical, social, and epidemiologic implications of this relatively new but rapidly emerging area in medical sciences. Bibliometric analysis of most-cited publications from Web of Science databases. Not applicable. None. None. Most productive and frequently cited investigators, institutions, and countries and specific areas of research, scientific collaborations, and comparison of the growth of reproductive medicine research compared with other areas of medical investigation such as obstetrics and gynecology and related science categories. We found that 90 investigators with more than 1,000 citations had jointly published 4,010 articles. A continued rise in the impact factor of reproductive medicine journals was seen. The number of publications in reproductive medicine grew more rapidly compared with other science categories. Presently 22% of highly cited articles in reproductive medicine research are published in journals belonging to science categories outside reproductive medicine. The most-cited study groups are situated in the Netherlands, Belgium, Spain, the United States, and the United Kingdom, and collaborative studies have been increasing. Reproductive medicine research and subsequent clinical development have attained scientific growth and maturity. High-quality research is increasingly being published in high-impact journals. The increase in (inter)national collaborations seems to be key to the field's success. Copyright © 2015 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

  19. Mapping the literature of pediatric nursing: update and implications for library services

    PubMed Central

    Watwood, Carol L.

    2016-01-01

    Objective The purpose of this study was to identify core journals and other types of literature cited in four major pediatric nursing journals and to characterize coverage of these resources in major bibliographic databases. The study was part of the “Mapping the Literature of Nursing Project” of the Medical Library Association's Nursing and Allied Health Resource Section. It updates a similar analysis published in 2006 and determines whether citation patterns have changed over time. Methods Cited references from articles published in 4 pediatric nursing journals between 2011 and 2013 were collected. Cited journal titles were ranked according to number of times cited and analyzed according to Bradford's Law of Scattering and the 80/20 rule to identify the most frequently cited journals. Five databases were surveyed to assess the coverage of the most-often-cited journals. The most frequently cited non-journal sources were also identified. Results Journals were the most frequently cited sources, followed by books, government documents, Internet resources, and miscellaneous resources. Most cited sources were cited within ten years of their publication, which was particularly true for government documents and Internet resources. Scopus had complete coverage of the most frequently cited journals, whereas PubMed had nearly complete coverage. Conclusions Compared with the 2006 study, the list of top-cited journals referenced by pediatric nursing researchers has remained relatively stable, but the number of cited journal titles has increased. Book citations have declined, and Internet and government document references have increased. These findings suggest that librarians should retain subscriptions to frequently cited journal titles, provide efficient document delivery of articles from infrequently used journals, de-emphasize but not eliminate books, and connect patrons with useful open-access Internet resources. PMID:27822148

  20. Knockdown of Cbp/P300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 2 inhibits cell division and increases apoptosis in gastric cancer.

    PubMed

    Tang, Ze; He, Gan; Xu, Jie; Zhongfu, Li

    2017-05-01

    Cbp/P300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 2 (CITED2) is a pleiotropic protein associated with numerous cell functions, including transcription and differentiation. The role of CITED2 has been investigated in a number of malignancies; however, the roles of this protein in gastric cancers remain unclear. Therefore, we determined the role of CITED2 in gastric cancers. Gastric cancer cell lines (MKN74, MKN28, 7901, and AGS) were used to assess CITED2 transcript levels. Messenger RNA levels were determined using quantitative polymerase chain reaction. Lentiviral vectors containing CITED2 small interfering RNA were used to knockdown CITED2 expression. Cell proliferation was assessed with fluorescent imaging and 3-(4,5-dimethylthiazol-2-yl)-2,5- diphenyltetrazolium bromide assays. Apoptosis and cell cycle stages were assessed through flow cytometry, and formation of colonies was determined using a fluorescent microscope. All cell lines tested in this study expressed CITED2. The cell line expressing the highest levels of CITED2 (MKN74) showed significant knockdown of endogenous CITED2 expression on lentiviral infection. Cell proliferation was shown to be lower in CITED2 knockdown MKN74 cells. G1/S-phase cell cycle arrest was observed on silencing of CITED2 in MKN74 cells. A significant increase in apoptosis was observed on CITED2 knock down in MKN74 cells, while colony forming ability was significantly inhibited after knock down of CITED2. CITED2 supports gastric cancer cell colony formation and proliferation while inhibiting apoptosis making it a potential gene therapy target for gastric cancer. Copyright © 2016 Elsevier Inc. All rights reserved.

  1. Mapping the literature of pediatric nursing: update and implications for library services.

    PubMed

    Watwood, Carol L

    2016-10-01

    The purpose of this study was to identify core journals and other types of literature cited in four major pediatric nursing journals and to characterize coverage of these resources in major bibliographic databases. The study was part of the "Mapping the Literature of Nursing Project" of the Medical Library Association's Nursing and Allied Health Resource Section. It updates a similar analysis published in 2006 and determines whether citation patterns have changed over time. Cited references from articles published in 4 pediatric nursing journals between 2011 and 2013 were collected. Cited journal titles were ranked according to number of times cited and analyzed according to Bradford's Law of Scattering and the 80/20 rule to identify the most frequently cited journals. Five databases were surveyed to assess the coverage of the most-often-cited journals. The most frequently cited non-journal sources were also identified. Journals were the most frequently cited sources, followed by books, government documents, Internet resources, and miscellaneous resources. Most cited sources were cited within ten years of their publication, which was particularly true for government documents and Internet resources. Scopus had complete coverage of the most frequently cited journals, whereas PubMed had nearly complete coverage. Compared with the 2006 study, the list of top-cited journals referenced by pediatric nursing researchers has remained relatively stable, but the number of cited journal titles has increased. Book citations have declined, and Internet and government document references have increased. These findings suggest that librarians should retain subscriptions to frequently cited journal titles, provide efficient document delivery of articles from infrequently used journals, de-emphasize but not eliminate books, and connect patrons with useful open-access Internet resources.

  2. Here, there and everywhere: The art and science of optics at work

    NASA Astrophysics Data System (ADS)

    Ambrosini, Dario; Ferraro, Pietro

    2018-05-01

    Optics, the ancient science of vision and light [1-5] can look forward to a "bright" future [6,7], as its applications are now ubiquitous in fields as diverse as science, engineering, technology, medicine and everyday life. Optical methods play a crucial and often revolutionary role in non-destructive testing, biomedical applications, microscopy, cultural heritage protection, advanced imaging in medicine, development of self-driving cars, astronomy, remote sensing, and manufacturing to cite a few examples.

  3. How Computers Are Used in the Teaching of Music and Speculations about How Artificial Intelligence Could Be Applied to Radically Improve the Learning of Compositional Skills. CITE Report No. 6.

    ERIC Educational Resources Information Center

    Holland, Simon

    This paper forms part of a preliminary survey for work on the application of artificial intelligence theories and techniques to the learning of music composition skills. The paper deals with present day applications of computers to the teaching of music and speculations about how artificial intelligence might be used to foster music composition in…

  4. Biosafety: guidelines for working with pathogenic and infectious microorganisms.

    PubMed

    Coico, Richard; Lunn, George

    2005-11-01

    This unit, in conjunction with local and national guidelines and regulations, provides the basic biosafety information needed to perform the procedures detailed in this manual. Topics discussed include routine precautions when working with biohazards, disinfectants, disposal of biohazards, biosafety levels (as established by the U.S. National Institutes of Health, and the Centers for Disease Control and Prevention), animal facilities, and clinical laboratories. In addition, resources for more information are provided in the Literature Cited and Key References sections and in URLs given text and within the Internet Resources section.

  5. Ebola virus disease: radiology preparedness.

    PubMed

    Bluemke, David A; Meltzer, Carolyn C

    2015-02-01

    At present, there is a major emphasis on Ebola virus disease (EVD) preparedness training at medical facilities throughout the United States. Failure to have proper EVD procedures in place was cited as a major reason for infection of medical personnel in the United States. Medical imaging does not provide diagnosis of EVD, but patient assessment in the emergency department and treatment isolation care unit is likely to require imaging services. The purpose of this article is to present an overview of relevant aspects of EVD disease and preparedness relevant to the radiologic community. © RSNA, 2014.

  6. Craniocervical chiropractic procedures – a précis of upper cervical chiropractic

    PubMed Central

    Woodfield, H. Charles; York, Craig; Rochester, Roderic P.; Bales, Scott; Beebe, Mychal; Salminen, Bryan; Scholten, Jeffrey N.

    2015-01-01

    Presented here is a narrative review of upper cervical procedures intended to facilitate understanding and to increase knowledge of upper cervical chiropractic care. Safety, efficacy, common misconceptions, and research are discussed, allowing practitioners, chiropractic students, and the general public to make informed decisions regarding utilization and referrals for this distinctive type of chiropractic care. Upper cervical techniques share the same theoretical paradigm in that the primary subluxation exists in the upper cervical spine. These procedures use similar assessments to determine if spinal intervention is necessary and successful once delivered. The major difference involves their use of either an articular or orthogonal radiograph analysis model when determining the presence of a misalignment. Adverse events following an upper cervical adjustment consist of mild symptomatic reactions of short-duration (< 24-hours). Due to a lack of quality and indexed references, information contained herein is limited by the significance of literature cited, which included non-indexed and/or non-peer reviewed sources. PMID:26136610

  7. A photometric mode identification method, including an improved non-adiabatic treatment of the atmosphere

    NASA Astrophysics Data System (ADS)

    Dupret, M.-A.; De Ridder, J.; De Cat, P.; Aerts, C.; Scuflaire, R.; Noels, A.; Thoul, A.

    2003-02-01

    We present an improved version of the method of photometric mode identification of Heynderickx et al. (\\cite{hey}). Our new version is based on the inclusion of precise non-adiabatic eigenfunctions determined in the outer stellar atmosphere according to the formalism recently proposed by Dupret et al. (\\cite{dup}). Our improved photometric mode identification technique is therefore no longer dependent on ad hoc parameters for the non-adiabatic effects. It contains the complete physical conditions of the outer atmosphere of the star, provided that rotation does not play a key role. We apply our method to the two slowly pulsating B stars HD 74560 and HD 138764 and to the beta Cephei star EN (16) Lac. Besides identifying the degree l of the pulsating stars, our method is also a tool for improving the knowledge of stellar interiors and atmospheres, by imposing constraints on parameters such as the metallicity and the mixing-length parameter alpha (a procedure we label non-adiabatic asteroseismology). The non-adiabatic eigenfunctions needed for the mode identification are available upon request from the authors.

  8. [Flexible endoscope in thoracic surgery: CITES or cVATS?].

    PubMed

    Assouad, J; Fénane, H; Masmoudi, H; Giol, M; Karsenti, A; Gounant, V; Grunenwald, D

    2013-10-01

    Early pain and persistent parietal disorders remains a major unresolved problem in thoracic surgery. Thoracotomy and the use of multiple ports in most Video Assisted Thoracic Surgery (VATS) procedures are the major cause of this persistent pain. For the last decade, a few publications describing the use of either single incision VATS and cervical thoracic approaches have been reported without significant results in comparison with current used techniques. Intercostals compression during surgery and early after by intercostals chest tube placement, are probably the major cause of postoperative pain. Flexible endoscope is currently used in several surgeries and will take more and more importance in our daily use in thoracic surgery. Instrument flexibility allows its use through minimally invasive approaches and offers a very interesting intra-thoracic navigation. We describe here the first use in France of a flexible endoscope in thoracic surgery through a single cervical incision to perform simultaneous exploration and biopsies of the mediastinum and right pleura using the original approach of Cervical Incision Thoracic Endoscopic Surgery (CITES). Copyright © 2013 Elsevier Masson SAS. All rights reserved.

  9. Speech and language adverse effects after thalamotomy and deep brain stimulation in patients with movement disorders: A meta-analysis.

    PubMed

    Alomar, Soha; King, Nicolas K K; Tam, Joseph; Bari, Ausaf A; Hamani, Clement; Lozano, Andres M

    2017-01-01

    The thalamus has been a surgical target for the treatment of various movement disorders. Commonly used therapeutic modalities include ablative and nonablative procedures. A major clinical side effect of thalamic surgery is the appearance of speech problems. This review summarizes the data on the development of speech problems after thalamic surgery. A systematic review and meta-analysis was performed using nine databases, including Medline, Web of Science, and Cochrane Library. We also checked for articles by searching citing and cited articles. We retrieved studies between 1960 and September 2014. Of a total of 2,320 patients, 19.8% (confidence interval: 14.8-25.9) had speech difficulty after thalamotomy. Speech difficulty occurred in 15% (confidence interval: 9.8-22.2) of those treated with a unilaterally and 40.6% (confidence interval: 29.5-52.8) of those treated bilaterally. Speech impairment was noticed 2- to 3-fold more commonly after left-sided procedures (40.7% vs. 15.2%). Of the 572 patients that underwent DBS, 19.4% (confidence interval: 13.1-27.8) experienced speech difficulty. Subgroup analysis revealed that this complication occurs in 10.2% (confidence interval: 7.4-13.9) of patients treated unilaterally and 34.6% (confidence interval: 21.6-50.4) treated bilaterally. After thalamotomy, the risk was higher in Parkinson's patients compared to patients with essential tremor: 19.8% versus 4.5% in the unilateral group and 42.5% versus 13.9% in the bilateral group. After DBS, this rate was higher in essential tremor patients. Both lesioning and stimulation thalamic surgery produce adverse effects on speech. Left-sided and bilateral procedures are approximately 3-fold more likely to cause speech difficulty. This effect was higher after thalamotomy compared to DBS. In the thalamotomy group, the risk was higher in Parkinson's patients, whereas in the DBS group it was higher in patients with essential tremor. Understanding the pathophysiology of speech disturbance after thalamic procedures is a priority. © 2017 International Parkinson and Movement Disorder Society. © 2016 International Parkinson and Movement Disorder Society.

  10. CITED2 modulates estrogen receptor transcriptional activity in breast cancer cells

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lau, Wen Min; Doucet, Michele; Huang, David

    2013-07-26

    Highlights: •The effects of elevated CITED2 on ER function in breast cancer cells are examined. •CITED2 enhances cell growth in the absence of estrogen and presence of tamoxifen. •CITED2 functions as a transcriptional co-activator of ER in breast cancer cells. -- Abstract: Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 2 (CITED2) is a member of the CITED family of non-DNA binding transcriptional co-activators of the p300/CBP-mediated transcription complex. Previously, we identified CITED2 as being overexpressed in human breast tumors relative to normal mammary epithelium. Upon further investigation within the estrogen receptor (ER)-positive subset of these breast tumor samples, we found thatmore » CITED2 mRNA expression was elevated in those associated with poor survival. In light of this observation, we investigated the effect of elevated CITED2 levels on ER function. While ectopic overexpression of CITED2 in three ER-positive breast cancer cell lines (MCF-7, T47D, and CAMA-1) did not alter cell proliferation in complete media, growth was markedly enhanced in the absence of exogenous estrogen. Correspondingly, cells overexpressing CITED2 demonstrated reduced sensitivity to the growth inhibitory effects of the selective estrogen receptor modulator, 4-hydroxytamoxifen. Subsequent studies revealed that basal ER transcriptional activity was elevated in CITED2-overexpressing cells and was further increased upon the addition of estrogen. Similarly, basal and estrogen-induced expression of the ER-regulated genes trefoil factor 1 (TFF1) and progesterone receptor (PGR) was higher in cells overexpressing CITED2. Concordant with this observation, ChIP analysis revealed higher basal levels of CITED2 localized to the TFF-1 and PGR promoters in cells with ectopic overexpression of CITED2, and these levels were elevated further in response to estrogen stimulation. Taken together, these data indicate that CITED2 functions as a transcriptional co-activator of ER in breast cancer cells and that its increased expression in tumors may result in estrogen-independent ER activation, thereby reducing estrogen dependence and response to anti-estrogen therapy.« less

  11. The applied value of public investments in biomedical research.

    PubMed

    Li, Danielle; Azoulay, Pierre; Sampat, Bhaven N

    2017-04-07

    Scientists and policy-makers have long argued that public investments in science have practical applications. Using data on patents linked to U.S. National Institutes of Health (NIH) grants over a 27-year period, we provide a large-scale accounting of linkages between public research investments and subsequent patenting. We find that about 10% of NIH grants generate a patent directly but 30% generate articles that are subsequently cited by patents. Although policy-makers often focus on direct patenting by academic scientists, the bulk of the effect of NIH research on patenting appears to be indirect. We also find no systematic relationship between the "basic" versus "applied" research focus of a grant and its propensity to be cited by a patent. Copyright © 2017, American Association for the Advancement of Science.

  12. Managing a Small Cat House, or, Applications of Feminist Social Psychology to Academic Administration in Small Colleges

    ERIC Educational Resources Information Center

    Madden, Margaret E.

    This paper discusses management strategies based on feminist social psychological principles, applies them to the administration of small colleges, and suggests their effectiveness for dealing with intelligent and independent faculty members. The principles cited are: (1) individuals are located in a sociological context that creates differences…

  13. Demand-Adjusted Shelf Availability Parameters: A Second Look.

    ERIC Educational Resources Information Center

    Schwarz, Philip

    1983-01-01

    Data gathered in application of Paul Kantor's demand-adjusted shelf availability model to medium-sized academic library indicate significant differences in shelf availability when data are analyzed by last circulation date, acquisition date, and imprint date, and when they are gathered during periods of low and high use. Ten references are cited.…

  14. Gnotobiology in modern medicine

    NASA Technical Reports Server (NTRS)

    Podoprigora, G. I.

    1980-01-01

    A review is given of currently accepted theories and applications of gnotobiology. A brief history of gnotobiology is supplied. Problems involved in creating germ-free gnotobiota and the use of these animals in experimental biology are cited. Examples of how gnotobiology is used in modern medical practice illustrate the future prospects for this area of science.

  15. 78 FR 1206 - Notice of Availability of Government-Owned Inventions; Available for Licensing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-08

    .... Patent No. 8,238,924: Real-Time Optimization of Allocation of Resources//U.S. Patent No. 7,685,207: Adaptive Web-Based Asset Control System. ADDRESSES: Requests for copies of the patents cited should be...: Patent application 12/650,413: Finite State Machine Architecture for Software Development (a system for...

  16. 75 FR 5090 - Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-01

    ...). Grant applications for the ARRA: Limited Competition ``AHRQ Institutional Training Grants for CE'' (K12... disclosure under the above-cited statutes. SEP Meeting on: ARRA: Limited Competition ``AHRQ Institutional Training Grants for CE'' (K12). Date: March 3, 2010 (Open on March 3 from 8:00 a.m. to 8:15 a.m. and closed...

  17. An Investigation of Leadership Practices That Yield Success in Renewal Schools

    ERIC Educational Resources Information Center

    de Govia, Mauriciere A.

    2017-01-01

    The New York City Department of Education (NYCDOE) set forth the Renewal School initiative as a method of school turnaround that preserves the existing school community; with necessary leadership changes when applicable, and supplied human and operational resources. Educational research has cited that school leadership is the second leading…

  18. 10 CFR 782.5 - Contents of communication initiating claim.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 4 2011-01-01 2011-01-01 false Contents of communication initiating claim. 782.5 Section 782.5 Energy DEPARTMENT OF ENERGY CLAIMS FOR PATENT AND COPYRIGHT INFRINGEMENT Requirements and... Department of Energy under any of the applicable statutes cited in § 782.3, must be actually communicated to...

  19. 10 CFR 782.5 - Contents of communication initiating claim.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Contents of communication initiating claim. 782.5 Section 782.5 Energy DEPARTMENT OF ENERGY CLAIMS FOR PATENT AND COPYRIGHT INFRINGEMENT Requirements and... Department of Energy under any of the applicable statutes cited in § 782.3, must be actually communicated to...

  20. Understanding the Soviet Threat: The Necessity of Analyzing Soviet Military Thought and Actions from a Soviet Perspective.

    DTIC Science & Technology

    1987-12-01

    discipline comparable to physics or chemistry in its application. This concept is quite unusual for an American, as military affairs are not often studied in...Sanderson cites definitions from The Pocket Oxford Dictionary, The 67 Oxford Dictionary of English Etymology , and Blackie ’s Compact Etymological

  1. Social Sciences in Forestry. A Current Selected Bibliography and Index. No. 69.

    ERIC Educational Resources Information Center

    Albrecht, Jean, Ed.

    1986-01-01

    This is the eighth issue of "Social Sciences in Forestry," which provides a current annotated bibliographic listing of references related to four major areas of forestry. The main categories include: (1) applications to forestry at large (containing citings on resources, history, legislation, policy, planning, appraisal and valuation,…

  2. 77 FR 5874 - Qualification of Drivers; Exemption Applications; Vision

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-06

    ... one crash in a CMV, for which he was cited for an unsecured load, and no other convictions for moving... crashes and no convictions for moving violations in a CMV. Gary Vines Mr. Vines, 47, has had complete loss... DEPARTMENT OF TRANSPORTATION Federal Motor Carrier Safety Administration [Docket No. FMCSA-2011...

  3. Why Teacher Leaders Don't Want to Be Principals: Evidence from Arkansas

    ERIC Educational Resources Information Center

    Hewitt, Paul M.; Pijanowski, John C.; Denny, George S.

    2009-01-01

    This study investigates why teachers, identified by their school principal as being leaders or having leadership potential, chose not to become school principals. At a time in which the literature is reporting a shortage of qualified applicants for school administrative positions the identified reasons most cited by teacher leaders include…

  4. 50 CFR 23.53 - What are the requirements for obtaining a retrospective CITES document?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... section have been met. (5) The issuing Management Authority must provide all of the following information... sufficient information for us to find that your activity meets all of the following criteria: (1) The... a technical error that was not prompted by information provided by the applicant when issuing the...

  5. Space processing applications bibliography

    NASA Technical Reports Server (NTRS)

    1978-01-01

    This special bibliography lists 724 articles, papers, and reports which discuss various aspects of the use of the space environment for materials science research or for commercial enterprise. The potentialities of space processing and the improved materials processes that are made possible by the unique aspects of the space environment are emphasized. References identified in April, 1978 are cited.

  6. Leadership for Inter-Service Practice: Collaborative Leadership Lost in Translation? An Exploration

    ERIC Educational Resources Information Center

    Morrison, Marlene; Arthur, Linet

    2013-01-01

    Collaborative leadership is increasingly cited as the key framework for leadership in the 21st century. Yet its meaning remains complex, contested and frequently school-centric. This article examines understandings and applications in developing inter-service and inter-professional practices for children and young people. Drawing upon desk…

  7. Stories of Discovery Stimulate the Physics Major--A Polemic, with Examples.

    ERIC Educational Resources Information Center

    Leitner, Alfred

    1980-01-01

    Provides historical examples of intuitive discovery applicable to the teaching of physics for majors. Cites details for the discovery of Coulomb's law, emphasizing the roles of Joseph Priestley and Henry Cavendish. Also discusses the career of Ivar Giaever, a Nobel Prize winner of 1973 in solid state physics. (CS)

  8. 37 CFR 1.704 - Reduction of period of adjustment of patent term.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... TRADEMARK OFFICE, DEPARTMENT OF COMMERCE GENERAL RULES OF PRACTICE IN PATENT CASES Adjustment and Extension... first cited in any communication from a foreign patent office in a counterpart application and that this... 37 Patents, Trademarks, and Copyrights 1 2011-07-01 2011-07-01 false Reduction of period of...

  9. The "Self-Interested" Woman Academic: A Consideration of Beck's Model of the "Individualised Individual"

    ERIC Educational Resources Information Center

    Skelton, Christine

    2005-01-01

    The work of Ulrich Beck, particularly his concept of the "individualised individual", is increasingly cited by educational social scientists. As yet, there have been few empirical investigations that consider how applicable and relevant is the notion of the "individualised individual" in understanding how people make sense of…

  10. 7 CFR 97.105 - Denial of an application.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... denial, their numbers and dates and the names of the owners shall be stated. If prior foreign... the names of the owners shall be stated, and such other data shall be furnished, as may be necessary... cited as a reason for denial, the author (if any), title, date, pages or plates, and places of...

  11. 7 CFR 97.105 - Denial of an application.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... denial, their numbers and dates and the names of the owners shall be stated. If prior foreign... the names of the owners shall be stated, and such other data shall be furnished, as may be necessary... cited as a reason for denial, the author (if any), title, date, pages or plates, and places of...

  12. Baldrige Educational Quality Criteria as Another Model for Accreditation in American Community Colleges.

    ERIC Educational Resources Information Center

    Faulkner, Jane B.

    Institutional accreditation is a voluntary, non-governmental activity administered by the eight postsecondary accrediting institutions that are part of the six regional associations that serve colleges and universities in the United States. The author cites W. Edwards Deming's work on corporate quality improvement, and its applicability to…

  13. The General Adaptation Syndrome: Potential misapplications to resistance exercise.

    PubMed

    Buckner, Samuel L; Mouser, J Grant; Dankel, Scott J; Jessee, Matthew B; Mattocks, Kevin T; Loenneke, Jeremy P

    2017-11-01

    Within the resistance training literature, one of the most commonly cited tenets with respect to exercise programming is the "General Adaptation Syndrome" (GAS). The GAS is cited as a central theory behind the periodization of resistance exercise. However, after examining the original stress research by Hans Selye, the applications of GAS to resistance exercise may not be appropriate. To examine the original work of Hans Selye, as well as the original papers through which the GAS was established as a central theory for periodized resistance exercise. We conducted a review of Selye's work on the GAS, as well as the foundational papers through which this concept was applied to resistance exercise. The work of Hans Selye focused on the universal physiological stress responses noted upon exposure to toxic levels of a variety of pharmacological agents and stimuli. The extrapolations that have been made to resistance exercise appear loosely based on this concept and may not be an appropriate basis for application of the GAS to resistance exercise. Copyright © 2017 Sports Medicine Australia. Published by Elsevier Ltd. All rights reserved.

  14. [Analysis of the academic level and impact of ophthalmological periodicals in China].

    PubMed

    Xu, Xiao-quan; Mao, Wen-ming; Zheng, Jun-hai; Qu, Jia

    2009-04-01

    To analyse the whole level and impact of ophthalmological periodicals in China. It was studied by using bibliometrics analysis method. According to the data of CAJCCR in 2002 to 2007 and Chinese Citation Database in 2001 to 2007. The impact factor (IF), non-self-citing impact factor, total cited frequency, cited articles, immediacy index, rate of fund papers, web immediacy download rate, average value of h index were analysed and the non-self-citing rate, h(2)/n, high cited articles were calculated. In addition, the results of cited by cole databases at home and abroad. The average value of IF and cited frequency of 13 kinds of ophthalmological periodicals were 0.3940 and 657 respectively in 2001 to 2006, which were higher than that of D part of CAJCCR. The periodicals which the five indexes of IF, non-self-citing impact factor, total cited frequency, the non-self-citing rate, immediacy index, rate of fund papers, web immediacy download rate, average value of h index and h(2)/n, high cited articles were Top 5 and cited by five or more than five kinds of the cole databases at home and abroad were Chinese Journal of Ophthalmology, Chinese Journal of Ocular Fundus Diseases, Practical Chinese Journal of Ophthalmology and Chinese Journal of Optometry & Ophthalmology. Most of indexes of Chinese Journal of Ophthalmology were the first. There are big difference between the 13 kinds of ophthalmological periodicals. The qualities of some ophthalmological periodicals should be improved.

  15. Do younger Sleeping Beauties prefer a technological prince?

    PubMed

    van Raan, Anthony F J; Winnink, Jos J

    2018-01-01

    In this paper we investigate recent Sleeping Beauties cited in patents (SB-SNPRs). We find that the increasing trend of the relative number of SBs stopped around 1998. Moreover, we find that the time lag between the publication year of the SB-SNPRs and their first citation in a patent is becoming shorter in recent years. Our observations also suggest that, on average, in the more recent years SBs are awakened increasingly earlier by a 'technological prince' rather than by a 'scientific prince'. These observations suggest that SBs with technological importance are 'discovered' earlier in an application-oriented context. Then, because of this earlier recognized technological relevance, papers may be cited also earlier in a scientific context. Thus early recognized technological relevance may 'prevent' papers to become an SB. The scientific impact of Sleeping Beauties is generally not necessarily related to the technological importance of the SBs, as far as measured with number and impact of the citing patents. The analysis of the occurrence of inventor-author relations as well as the citation years of inventor-author patents suggest that the scientific awakening of Sleeping Beauties only rarely occurs by inventor-author self-citation.

  16. Cited2 Gene Controls Pluripotency and Cardiomyocyte Differentiation of Murine Embryonic Stem Cells through Oct4 Gene*

    PubMed Central

    Li, Qiang; Ramírez-Bergeron, Diana L.; Dunwoodie, Sally L.; Yang, Yu-Chung

    2012-01-01

    Cited2 (CBP/p300-interacting transactivator with glutamic acid (E)/aspartic acid (D)-rich tail 2) is a transcriptional modulator critical for the development of multiple organs. Although many Cited2-mediated phenotypes and molecular events have been well characterized using in vivo genetic murine models, Cited2-directed cell fate decision in embryonic stem cells (ESCs) remains elusive. In this study, we examined the role of Cited2 in the maintenance of stemness and pluripotency of murine ESCs by a gene-targeting approach. Cited2 knock-out (Cited2Δ/−, KO) ESCs display defective differentiation. Loss of Cited2 in differentiating ESCs results in delayed silencing of the genes involved in the maintenance of pluripotency and self-renewal of stem cells (Oct4, Klf4, Sox2, and c-Myc) and the disturbance in cardiomyocyte, hematopoietic, and neuronal differentiation. In addition, Cited2 KO ESCs experience a delayed induction of cardiomyocyte differentiation-associated proteins, NFAT3 (along with the reduced expression of NFAT3 target genes, Nkx2.5 and β-MHC), N-cadherin, and smooth muscle actin. CITED2 is recruited to the Oct4 promoter to regulate its expression during early ESC differentiation. This is the first demonstration that Cited2 controls ESC pluripotency and differentiation via direct regulation of Oct4 gene expression. PMID:22761414

  17. Relativistic corrections to fractal analyses of the galaxy distribution

    NASA Astrophysics Data System (ADS)

    Célérier, M.-N.; Thieberger, R.

    2001-02-01

    The effect of curvature on the results of fractal analyses of the galaxy distribution is investigated. We show that, if the universe satisfies the criteria of a wide class of parabolic homogeneous models, the observers measuring the fractal index with the integrated conditional density procedure may use the Hubble formula, without having to allow for curvature, out to distances of 600 Mpc, and possibly far beyond. This contradicts a previous claim by Ribeiro (\\cite{r33}) that, in the Einstein-de Sitter case, relativistic corrections should be taken into account at much smaller scales. We state for the class of cosmological models under study, and give grounds for conjecture for others, that the averaging procedure has a smoothing effect and that, therefore, the redshift-distance relation provides an upper limit to the relativistic corrections involved in such analyses.

  18. Alternative general-aircraft engines

    NASA Technical Reports Server (NTRS)

    Tomazic, W. A.

    1976-01-01

    The most promising alternative engine (or engines) for application to general aircraft in the post-1985 time period was defined, and the level of technology was cited to the point where confident development of a new engine can begin early in the 1980's. Low emissions, multifuel capability, and fuel economy were emphasized. Six alternative propulsion concepts were considered to be viable candidates for future general-aircraft application: the advanced spark-ignition piston, rotary combustion, two- and four-stroke diesel, Stirling, and gas turbine engines.

  19. Gerris Flow Solver: Implementation and Application

    DTIC Science & Technology

    2013-05-12

    2010), as well as tsunamis (Popinet 2011; 2012). The OMEGA model ( Bacon et al., 2000; Boybeyi et al., 2001) took a different approach to adaptivity...application of the model system to problems of interest. Cited References D. P. Bacon , N. N. Ahmad, et al. (2000), A dynamically adapting weather...Geophysical Union, Washington, DC, 1–16. Z. Boybeyi, N. N. Ahmad, D. P. Bacon , T. J. Dunn, M. S. Hall, P. C. S. Lee, R. A. Sarma, and T. R. Wait (2001

  20. Fundamentals of dielectric properties measurements and agricultural applications.

    PubMed

    Nelson, Stuart O

    2010-01-01

    Dielectrics and dielectric properties are defined generally and dielectric measurement methods and equipment are described for various frequency ranges from audio frequencies through microwave frequencies. These include impedance and admittance bridges, resonant frequency, transmission-line, and free-space methods in the frequency domain and time-domain and broadband techniques. Many references are cited describing methods in detail and giving sources of dielectric properties data. Finally a few applications for such data are presented and sources of tabulated and dielectric properties data bases are identified.

  1. Diagnosis and prediction of neuroendocrine liver metastases: a protocol of six systematic reviews.

    PubMed

    Arigoni, Stephan; Ignjatovic, Stefan; Sager, Patrizia; Betschart, Jonas; Buerge, Tobias; Wachtl, Josephine; Tschuor, Christoph; Limani, Perparim; Puhan, Milo A; Lesurtel, Mickael; Raptis, Dimitri A; Breitenstein, Stefan

    2013-12-23

    Patients with hepatic metastases from neuroendocrine tumors (NETs) benefit from an early diagnosis, which is crucial for the optimal therapy and management. Diagnostic procedures include morphological and functional imaging, identification of biomarkers, and biopsy. The aim of six systematic reviews discussed in this study is to assess the predictive value of Ki67 index and other biomarkers, to compare the diagnostic accuracy of morphological and functional imaging, and to define the role of biopsy in the diagnosis and prediction of neuroendocrine tumor liver metastases. An objective group of librarians will provide an electronic search strategy to examine the following databases: MEDLINE, EMBASE and The Cochrane Library (Cochrane Database of Systematic Reviews, Cochrane Central Register of Controlled Trials (CENTRAL), Database of Abstracts of Reviews of Effects). There will be no restriction concerning language and publication date. The qualitative and quantitative synthesis of the systematic review will be conducted with randomized controlled trials (RCT), prospective and retrospective comparative cohort studies, and case-control studies. Case series will be collected in a separate database and only used for descriptive purposes. This study is ongoing and presents a protocol of six systematic reviews to elucidate the role of histopathological and biochemical markers, biopsies of the primary tumor and the metastases as well as morphological and functional imaging modalities for the diagnosis and prediction of neuroendocrine liver metastases. These systematic reviews will assess the value and accuracy of several diagnostic modalities in patients with NET liver metastases, and will provide a basis for the development of clinical practice guidelines. The systematic reviews have been prospectively registered with the International Prospective Register of Systematic Reviews (PROSPERO): CRD42012002644; http://www.metaxis.com/prospero/full_doc.asp?RecordID=2644 (Archived by WebCite at http://www.webcitation.org/6LzCLd5sF), CRD42012002647; http://www.metaxis.com/prospero/full_doc.asp?RecordID=2647 (Archived by WebCite at http://www.webcitation.org/6LzCRnZnO), CRD42012002648; http://www.metaxis.com/prospero/full_doc.asp?RecordID=2648 (Archived by WebCite at http://www.webcitation.org/6LzCVeuVR), CRD42012002649; http://www.metaxis.com/prospero/full_doc.asp?RecordID=2649 (Archived by WebCite at http://www.webcitation.org/6LzCZzZWU), CRD42012002650; http://www.metaxis.com/prospero/full_doc.asp?RecordID=2650 (Archived by WebCite at http://www.webcitation.org/6LzDPhGb8), CRD42012002651; http://www.crd.york.ac.uk/PROSPERO/display_record.asp?ID=CRD42012002651#.UrMglPRDuVo (Archived by WebCite at http://www.webcitation.org/6LzClCNff).

  2. 48 CFR 1201.105-2 - Arrangement of regulations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... chapter 12 will be cited by “FAR” followed by the FAR numbered cite, and cross reference to the TAM in (TAR) 48 CFR chapter 12 will be cited by “TAM” followed by the TAM numbered cite. References to...

  3. NASA patent abstracts bibliography: A continuing bibliography. Section 1: Abstracts (supplement 05)

    NASA Technical Reports Server (NTRS)

    1974-01-01

    This bibliography is issued in two sections: Section 1 - Abstracts, and section 2 - Indexes. The abstract section cites 217 patents and applications for patent introduced into the NASA scientific and technical information system during the period of January 1974 through June 1974. Each entry consists of a citation, an abstract, and, in most cases, a key illustration selected from the patent or application for patent. The index section contains entries for 2653 patent and application for patent citations covering the period May 1969 through June 1974. The index section contains five indexes -- subject, inventor, source, number and accession number.

  4. Application of computational aerodynamics methods to the design and analysis of transport aircraft

    NASA Technical Reports Server (NTRS)

    Da Costa, A. L.

    1978-01-01

    The application and validation of several computational aerodynamic methods in the design and analysis of transport aircraft is established. An assessment is made concerning more recently developed methods that solve three-dimensional transonic flow and boundary layers on wings. Capabilities of subsonic aerodynamic methods are demonstrated by several design and analysis efforts. Among the examples cited are the B747 Space Shuttle Carrier Aircraft analysis, nacelle integration for transport aircraft, and winglet optimization. The accuracy and applicability of a new three-dimensional viscous transonic method is demonstrated by comparison of computed results to experimental data

  5. An assessment of current clinical attitudes toward letrozole use in reproductive endocrinology practices.

    PubMed

    Malloch, Lindsay; Rhoton-Vlasak, Alice

    2013-12-01

    To assess the clinical use and practice attitudes among Society for Assisted Reproductive Technology (SART) members regarding the use of letrozole for ovulation induction and infertility treatment. The SART clinic physicians were mailed a cover letter and consent form, a two-page survey, and return envelope. The surveys were returned and analyzed using descriptive statistics. Not applicable. None. A 13-question survey. Reproductive endocrinology and infertility physicians use patterns and attitudes regarding letrozole. A total of 77.9% of physician prescribe letrozole. Of those who do not, 32.4% cited concern about the US Food and Drug Administration warning, 35.1% cited satisfaction with current medications, 25.7% cited both reasons, and 6.8% cited no experience with letrozole. Physicians (11.5%) were unaware of the US Food and Drug Administration warning. Physicians (99.7%) were aware that ovulation induction is an off-label use of letrozole. The most common use was for ovulation induction in patients with polycystic ovary syndrome (PCOS). Physicians (14.9%) prescribe letrozole as first-line ovulation therapy prior to clomid, 47.9% use for clomid failures, and 25.7% reported use in both situations. Most physicians surveyed use letrozole for ovulation induction despite the current US Food and Drug Administration warning. Even when accounting for nonrespondents, more than 25% of physicians indicated success with letrozole use. Questions regarding doses and clinical concerns about letrozole revealed no standardized manner of letrozole administration despite wide interest, therefore additional research is warranted. Copyright © 2013 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

  6. Distalization of Maxillary First Permanent Molar by Pendulum Appliance in Mixed Dentition Period

    PubMed Central

    Shetty, Prakashchandra; Anandakrishna, Latha; Rawat, Anuradha

    2017-01-01

    Introduction Mesial drifting of molar teeth in maxillary arch is corrected by movement of the molars distally. In addition to traditional distal movement techniques, such as extraoral force application and removable appliances, various intra-arch devices have been introduced since 1980s. These intra-arch appliances have nearly eliminated the need for patient cooperation. Case report The purpose of this paper is to report a case of 10-year-old male patient with loss of space in maxillary molar teeth treated by intra-arch appliance-pendulum appliance by distalization of maxillary first permanent molar teeth. Distaliza-tion of the permanent molar teeth helped in proper eruption of second premolar teeth without any extensive treatment procedures. Conclusion In the present case report, the treatment of developing malocclusion was corrected by utilizing the concept of interceptive orthodontics. Hence, correction of space loss in mixed dentition period using pendulum appliance can eliminate the fixed orthodontic therapy. How to cite this article Paranna S, Shetty P, Anandakrishna L, Rawat A. Distalization of Maxillary First Permanent Molar by Pendulum Appliance in Mixed Dentition Period. Int J Clin Pediatr Dent 2017;10(3):299-301. PMID:29104393

  7. Scientific collaboration and endorsement: Network analysis of coauthorship and citation networks

    PubMed Central

    Ding, Ying

    2010-01-01

    Scientific collaboration and endorsement are well-established research topics which utilize three kinds of methods: survey/questionnaire, bibliometrics, and complex network analysis. This paper combines topic modeling and path-finding algorithms to determine whether productive authors tend to collaborate with or cite researchers with the same or different interests, and whether highly cited authors tend to collaborate with or cite each other. Taking information retrieval as a test field, the results show that productive authors tend to directly coauthor with and closely cite colleagues sharing the same research interests; they do not generally collaborate directly with colleagues having different research topics, but instead directly or indirectly cite them; and highly cited authors do not generally coauthor with each other, but closely cite each other. PMID:21344057

  8. 48 CFR 306.304 - Approval of the justification.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... where the individual designated as the CA does not meet the requirements of FAR 6.304 (a)(3)(ii). This... acquisitions in the dollar amount cited in FAR 6.304(a)(2) through (a)(4), the CCO, if applicable, and the HCA shall indicate their review of, and concurrence with, the justification by signing the JOFOC. (a) The...

  9. 48 CFR 306.304 - Approval of the justification.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... where the individual designated as the CA does not meet the requirements of FAR 6.304 (a)(3)(ii). This... acquisitions in the dollar amount cited in FAR 6.304(a)(2) through (a)(4), the CCO, if applicable, and the HCA shall indicate their review of, and concurrence with, the justification by signing the JOFOC. (a) The...

  10. 48 CFR 306.304 - Approval of the justification.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... where the individual designated as the CA does not meet the requirements of FAR 6.304 (a)(3)(ii). This... acquisitions in the dollar amount cited in FAR 6.304(a)(2) through (a)(4), the CCO, if applicable, and the HCA shall indicate their review of, and concurrence with, the justification by signing the JOFOC. (a) The...

  11. 48 CFR 306.304 - Approval of the justification.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... where the individual designated as the CA does not meet the requirements of FAR 6.304 (a)(3)(ii). This... acquisitions in the dollar amount cited in FAR 6.304(a)(2) through (a)(4), the CCO, if applicable, and the HCA shall indicate their review of, and concurrence with, the justification by signing the JOFOC. (a) The...

  12. 76 FR 20082 - Koenigsegg Automotive AB; Morgan Motor Company Limited; Receipt of Applications for Renewals of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-11

    ... Volume Manufacturers In 2000, NHTSA upgraded the requirements for air bags in passenger cars and light... formed in 1999 to produce high-performance sports cars, which are not intended for daily commuting... cites the ``Quant concept car'' \\12\\ as one project. \\12\\ In footnote 1 in its petition, Koenigsegg...

  13. Probing the Human Brain with Stimulating Electrodes: The Story of Roberts Bartholow's (1874) Experiment on Mary Rafferty

    ERIC Educational Resources Information Center

    Harris, Lauren Julius; Almerigi, Jason B.

    2009-01-01

    Roberts Bartholow's 1874 experiment on Mary Rafferty is widely cited as the first demonstration, by direct application of stimulating electrodes, of the motor excitability of the human cerebral cortex. The many accounts of the experiment, however, leave certain questions and details unexamined or unresolved, especially about Bartholow's goals, the…

  14. Score Study Practices of Texas High School Choir Directors

    ERIC Educational Resources Information Center

    Rohwer, Debbie; Herring, Michelle; Moore, Jordan

    2014-01-01

    Score study combines the task of what music educators do to prepare for class everyday with many of the components that are taught in collegiate theory classes. While non-research articles have cited the practical application of score study techniques, there is a need for research on score study to describe the ways choral educators pragmatically…

  15. Isoflavonoids of the leguminosae.

    PubMed

    Veitch, Nigel C

    2013-07-01

    This account describes 275 new isoflavonoids published between 2008 and 2011 as constituents of the Leguminosae, commenting on their source, identification, biological activity, synthesis, and ecological or chemosystematic significance. Applications of hyphenated analytical techniques to the characterisation of Leguminosae isoflavonoids are also reviewed, together with advances in biosynthetic studies. A checklist of new compounds by species is given, and 226 references are cited.

  16. Worldwide Report, Arms Control.

    DTIC Science & Technology

    1985-06-13

    283086 JPRS-TAC-85-0 12 13 June 1985 Worldwide Report ARMS CONTROL 19980729 131 — . „_ | ^^CQWArpmr Approved fa pnbfi* nümam...retained. Headlines, editorial reports , and material enclosed in brackets [] are supplied by JPRS. Processing indicators such as [Text] or...JPRS number, title, date and author, if applicable, of publication be cited. Current JPRS publications are announced in Government Reports

  17. 78 FR 38537 - Federal Acquisition Regulation; Federal Acquisition Circular 2005-68; Small Entity Compliance Guide

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-26

    ... Entity Compliance Guide. SUMMARY: This document is issued under the joint authority of DOD, GSA, and NASA... whose name appears in the table below. Please cite FAC 2005-68 and the FAR case number. For information... Listed in FAC 2005-68 Subject FAR Case Analyst *Expansion of Applicability of the Senior Executive...

  18. Research Methods

    DTIC Science & Technology

    1992-01-01

    cognitive function. For example. physiological methods allow for visual sensitivity measurements in infants and children with about the same level of...potential (ERP), the event-related magnetic field (ERF), and pupillometry . Where possible, we cite specific experiments that deal with display or stimulus...technical barrier preventing the application of these methods to the analysis of human performance with color displays. Pupillometry . The pupillary

  19. Internationalising Work-Integrated Learning: Creating Global Citizens to Meet the Economic Crisis and the Skills Shortage

    ERIC Educational Resources Information Center

    Gamble, Natalie; Patrick, Carol-joy; Peach, Deborah

    2010-01-01

    Research indicates that for many multinational companies, the global skills shortage has made it difficult to attract competent workers to some international locations. In developing economies, business leaders often cite poor business acumen and little real-world experience as serious shortcomings in the domestic pool of applicants. In addition…

  20. [Classification of Histopathological Findings in the Liver Cited in the Pesticides Risk Assessment Reports Published by the Food Safety Commission of Japan and Thesaurus Construction Based on the International Harmonization of Nomenclature and Diagnostic (INHAND) Criteria].

    PubMed

    Inoue, Kaoru; Takahashi, Miwa; Umemura, Takashi; Yoshida, Midori

    2015-01-01

    Histopathological findings are important to the understanding of toxicity profiles of pesticides. The liver is often a target organ of chemicals. In the present study, histopathological findings in the liver cited in the pesticides risk assessment reports published by the Food Safety Commission of Japan were classified. The histopathological findings were obtained in repeated-dose 90-day oral toxicity studies of mice, rats and dogs and carcinogenicity studies of rodents. After the classification, a thesaurus was constructed based on the International Harmonization of Nomenclature and Diagnostic (INHAND) Criteria. We recommend the use of INHAND criteria in risk assessment reports to improve mutual understanding between applicants and risk assessors.

  1. Testing the effectiveness of an international conservation agreement: marketplace forensics and CITES caviar trade regulation.

    PubMed

    Doukakis, Phaedra; Pikitch, Ellen K; Rothschild, Anna; DeSalle, Rob; Amato, George; Kolokotronis, Sergios-Orestis

    2012-01-01

    The international wildlife trade is a key threat to biodiversity. Temporal genetic marketplace monitoring can determine if wildlife trade regulation efforts such as the Convention on International Trade in Endangered Species (CITES) are succeeding. Protected under CITES effective 1997, sturgeons and paddlefishes, the producers of black caviar, are flagship CITES species. We test whether CITES has limited the amount of fraudulent black caviar reaching the marketplace. Using mitochondrial DNA-based methods, we compare mislabeling in caviar and meat purchased in the New York City area pre and post CITES listing. Our recent sampling of this market reveals a decrease in mislabeled caviar (2006-2008; 10%; n = 90) compared to pre-CITES implementation (1995-1996; 19%; n = 95). Mislabeled caviar was found only in online purchase (n = 49 online/41 retail). Stricter controls on importing and exporting as per CITES policies may be having a positive conservation effect by limiting the amount of fraudulent caviar reaching the marketplace. Sturgeons and paddlefishes remain a conservation priority, however, due to continued overfishing and habitat degradation. Other marine and aquatic species stand to benefit from the international trade regulation that can result from CITES listing.

  2. Long Term Resource Monitoring Program procedures: fish monitoring

    USGS Publications Warehouse

    Ratcliff, Eric N.; Glittinger, Eric J.; O'Hara, T. Matt; Ickes, Brian S.

    2014-01-01

    This manual constitutes the second revision of the U.S. Army Corps of Engineers’ Upper Mississippi River Restoration-Environmental Management Program (UMRR-EMP) Long Term Resource Monitoring Program (LTRMP) element Fish Procedures Manual. The original (1988) manual merged and expanded on ideas and recommendations related to Upper Mississippi River fish sampling presented in several early documents. The first revision to the manual was made in 1995 reflecting important protocol changes, such as the adoption of a stratified random sampling design. The 1995 procedures manual has been an important document through the years and has been cited in many reports and scientific manuscripts. The resulting data collected by the LTRMP fish component represent the largest dataset on fish within the Upper Mississippi River System (UMRS) with more than 44,000 collections of approximately 5.7 million fish. The goal of this revision of the procedures manual is to document changes in LTRMP fish sampling procedures since 1995. Refinements to sampling methods become necessary as monitoring programs mature. Possible refinements are identified through field experiences (e.g., sampling techniques and safety protocols), data analysis (e.g., planned and studied gear efficiencies and reallocations of effort), and technological advances (e.g., electronic data entry). Other changes may be required because of financial necessity (i.e., unplanned effort reductions). This version of the LTRMP fish monitoring manual describes the most current (2014) procedures of the LTRMP fish component.

  3. 32 CFR 724.501 - Procedural rights of the applicant.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 5 2010-07-01 2010-07-01 false Procedural rights of the applicant. 724.501... DISCHARGE REVIEW BOARD Procedural Rights of the Applicant and Administrative Actions Preliminary To Discharge Review § 724.501 Procedural rights of the applicant. Each applicant has the following procedural...

  4. Trends and drivers of the aesthetic market during a turbulent economy.

    PubMed

    Wilson, Stelios C; Soares, Marc A; Reavey, Patrick L; Saadeh, Pierre B

    2014-06-01

    Aesthetic procedures are significant sources of revenue for plastic surgeons. With the popularity of nonsurgical aesthetic procedures, many plastic surgeons question how to best tailor their aesthetic practice. Revenue generated from surgical and minimally invasive aesthetic procedures performed in the United States between 2000 and 2011 was calculated from the American Society of Plastic Surgeons' annual reports. Regression analysis was performed against six commonly cited economic indicators. In 2011, revenue from minimally invasive procedures increased from $3.0 billion to $5.7 billion (90 percent growth), whereas revenue from surgical procedures decreased from $6.6 billion to $6.0 billion (10 percent decline). Between 2000 and 2011, minimally invasive procedure market share grew from 30 percent to nearly 50 percent. Linear regression analysis revealed significant correlations between surgical procedure revenue and indicators of macroeconomic climate: Dow Jones Industrial Average (R = 0.72; p < 0.01), Standard & Poor's 500 Index (R = 0.64, p < 0.05), and unemployment rate (R = -0.81; p < 0.001). Minimally invasive procedure revenue was significantly correlated with indicators related to microeconomic decision trends: disposable income per capita (R = 0.93; p < 0.001), real gross domestic product per capita (R = 0.88; p < 0.001), and home price index (R = 0.63; p < 0.05). No economic indicator in this study was found to be significantly correlated with both surgical and minimally invasive revenue. Despite economic turbulence, minimally invasive procedures are the most rapidly growing source of revenue and are poised to be the dominant source of revenue in the aesthetic market.

  5. 50 CFR 23.1 - What are the purposes of these regulations and CITES?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...), implement CITES through the Endangered Species Act (ESA). ... ENDANGERED SPECIES OF WILD FAUNA AND FLORA (CITES) Introduction § 23.1 What are the purposes of these... Trade in Endangered Species of Wild Fauna and Flora, also known as CITES, the Convention, the Treaty, or...

  6. 50 CFR 23.1 - What are the purposes of these regulations and CITES?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ...), implement CITES through the Endangered Species Act (ESA). ... ENDANGERED SPECIES OF WILD FAUNA AND FLORA (CITES) Introduction § 23.1 What are the purposes of these... Trade in Endangered Species of Wild Fauna and Flora, also known as CITES, the Convention, the Treaty, or...

  7. 50 CFR 23.1 - What are the purposes of these regulations and CITES?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...), implement CITES through the Endangered Species Act (ESA). ... ENDANGERED SPECIES OF WILD FAUNA AND FLORA (CITES) Introduction § 23.1 What are the purposes of these... Trade in Endangered Species of Wild Fauna and Flora, also known as CITES, the Convention, the Treaty, or...

  8. 50 CFR 23.1 - What are the purposes of these regulations and CITES?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...), implement CITES through the Endangered Species Act (ESA). ... ENDANGERED SPECIES OF WILD FAUNA AND FLORA (CITES) Introduction § 23.1 What are the purposes of these... Trade in Endangered Species of Wild Fauna and Flora, also known as CITES, the Convention, the Treaty, or...

  9. 50 CFR 23.1 - What are the purposes of these regulations and CITES?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...), implement CITES through the Endangered Species Act (ESA). ... ENDANGERED SPECIES OF WILD FAUNA AND FLORA (CITES) Introduction § 23.1 What are the purposes of these... Trade in Endangered Species of Wild Fauna and Flora, also known as CITES, the Convention, the Treaty, or...

  10. Extracting land use information from the earth resources technology satellite data by conventional interpretation methods

    NASA Technical Reports Server (NTRS)

    Vegas, P. L.

    1974-01-01

    A procedure for obtaining land use data from satellite imagery by the use of conventional interpretation methods is presented. The satellite is described briefly, and the advantages of various scales and multispectral scanner bands are discussed. Methods for obtaining satellite imagery and the sources of this imagery are given. Equipment used in the study is described, and samples of land use maps derived from satellite imagery are included together with the land use classification system used. Accuracy percentages are cited and are compared to those of a previous experiment using small scale aerial photography.

  11. Biosafety: guidelines for working with pathogenic and infectious microorganisms.

    PubMed

    Burnett, LouAnn C; Lunn, George; Coico, Richard

    2009-05-01

    This unit, in conjunction with local and national guidelines and regulations (see APPENDIX 1B), provides the basic biosafety information needed to perform the procedures detailed in this manual. Topics discussed include routine precautions when working with biohazards, disinfectants, disposal of biohazards, biosafety levels (as established by the U.S. National Institutes of Health and the U.S. Centers for Disease Control and Prevention), animal facilities, and clinical laboratories. In addition, resources for more information are provided in the Literature Cited and Key References sections and in URLs given within the text, as well as the Internet Resources section.

  12. Frequently cited journals in forensic psychology.

    PubMed

    Black, Steve

    2012-02-01

    Works cited in six forensic psychology journals published 2008-2010 were counted to identify the most frequently cited journals. The sample of works cited (N = 21,776) was not a definitive ranked list of important journals in forensic psychology, but was large enough to indicate high-impact journals. The list of frequently cited publications included more general psychiatry and psychology journals than titles specific to forensic psychology. The implications of the proportion of general versus specific titles for collections supporting research in forensic psychology were discussed.

  13. Bone Marrow Aspirate Concentrate for Cartilage Defects of the Knee: From Bench to Bedside Evidence.

    PubMed

    Cotter, Eric J; Wang, Kevin C; Yanke, Adam B; Chubinskaya, Susan

    2018-04-01

    Objective To critically evaluate the current basic science, translational, and clinical data regarding bone marrow aspirate concentrate (BMAC) in the setting of focal cartilage defects of the knee and describe clinical indications and future research questions surrounding the clinical utility of BMAC for treatment of these lesions. Design A literature search was performed using the PubMed and Ovid MEDLINE databases for studies in English (1980-2017) using keywords, including ["bone marrow aspirate" and "cartilage"], ["mesenchymal stem cells" and "cartilage"], and ["bone marrow aspirate" and "mesenchymal stem cells" and "orthopedics"]. A total of 1832 articles were reviewed by 2 independent authors and additional literature found through scanning references of cited articles. Results BMAC has demonstrated promising results in the clinical application for repair of chondral defects as an adjuvant procedure or as an independent management technique. A subcomponent of BMAC, bone marrow derived-mesenchymal stem cells (MSCs) possess the ability to differentiate into cells important for osteogenesis and chondrogenesis. Modulation of paracrine signaling is perhaps the most important function of BM-MSCs in this setting. In an effort to increase the cellular yield, authors have shown the ability to expand BM-MSCs in culture while maintaining phenotype. Conclusions Translational studies have demonstrated good clinical efficacy of BMAC both concomitant with cartilage restoration procedures, at defined time points after surgery, and as isolated injections. Early clinical data suggests BMAC may help stimulate a more robust hyaline cartilage repair tissue response. Numerous questions remain regarding BMAC usage, including cell source, cell expansion, optimal pathology, and injection timing and quantity.

  14. State of the field survey: spinal cord stimulator use by academic pain medicine practices.

    PubMed

    Gharibo, Christopher; Laux, Gary; Forzani, Brian R; Sellars, Christopher; Kim, Eric; Zou, Shengping

    2014-02-01

    The concept of neuromodulation via the use of spinal cord stimulators (SCS) was first established over forty years ago. Since then, its popularity has grown as numerous studies have demonstrated its utility to reduce chronic pain, improve patient function, and reduce long-term health care costs. The aim of this study was to update the pain medicine community on the evolution of SCS practice trends in academic centers. Ninety-three pain medicine fellowship programs in the United States were identified from the Accreditation Council for Graduate Medical Education Website and were contacted to participate in an internet survey. A 37-item questionnaire was inspired by a previous study performed by Fanciullo et al. Questions focused on three main themes regarding SCS clinical application, namely demographics, education, and technical matters. Completed surveys were received from 50 institutions, all of which reported performing SCS interventions. Annual implants ranged from 0 to 150. Fellowship training was cited as the most valuable modality for learning implantation. Nearly all programs reported manufacturer representative participation during SCS procedures, with a minority of program directors discouraging their involvement in fellow education. SCS trials were performed exclusively on an outpatient basis. The average length for trials was 4-7 days. The most common indication for SCS implantation was failed back surgery syndrome, which also had the highest 2-year success rate. Post procedure, patients generally were followed up every 2-4 weeks for device reprogramming, which was performed by company representatives 92% of the time. Standardized SCS training is imperative as the implementation of neuromodulation therapy continues to increase. Wiley Periodicals, Inc.

  15. Critical appraisal of cardiology guidelines on revascularisation: clinical practice.

    PubMed

    Dobies, David R; Barber, Kimberly R

    2018-01-01

    Evidence-based medicine (EBM) provides clinicians with beneficial information. Nonetheless, study findings are often arbitrary, speculative or provisional. The current state of misleading evidence exists in all applications, including those for guideline recommendations. We conductedan appraisal of the American College of Cardiologyand European Society of Cardiology Guidelines for revascularisation of complex coronary anatomy to determine the veracity of the evidence that recommendations were based on. Study-specific critical appraisals were conducted by the authors on the 5-year Synergy between percutaneous coronary intervention with Taxus and cardiac surgery (SYNTAX) and future revascularisation evaluation in patients with diabetes mellitus: optimal management of multivessel disease (FREEDOM) Trials. Each appraisal was performed according the standard EBM practices. A thorough design and analytic critique was performed for each study and the results presented and explained. The guideline recommendations were reviewed in terms of the veracity of the evidence cited. The relative difference in major adverse cardiac and cerebrovascular event (MAACE) rates between coronary artery bypass grafting (CABG) and percutaneous coronary intervention (PCI) are not the 30% level reported by the SYNTAX Trial but closer to 11% difference when study limitations are factored in. Similarly, the 30% effect size in MAACE rates between procedures from the FREEDOM Trial is closer to a non-significant 5% relative difference when limitations are adjusted for. Based on the actual findings of each study, outcomes from procedures by CABG or PCI for multivessel revascularisation are similar and contradict the conclusions of the study authors as well as the recommendations. These recommendations fail to inform current clinical practice.

  16. Spectrophotometric and spectrofluorimetric methods for analysis of tramadol, acebutolol and dothiepin in pharmaceutical preparations

    NASA Astrophysics Data System (ADS)

    Abdellatef, Hisham E.; El-Henawee, Magda M.; El-Sayed, Heba M.; Ayad, Magda M.

    2006-12-01

    Sensitive spectrophotometric and spectrofluorimetric methods are described for the determination of tramadol, acebutolol and dothiepin (dosulepin) hydrochlorides. The two methods are based on the condensation of the cited drugs with the mixed anhydrides of malonic and acetic acids at 60 °C for 25-40 min. The coloured condensation products are suitable for the spectrophotometric and spectrofluorimetric determination at 329-333 and 431-434 nm (excitation at 389 nm), respectively. For the spectrophotometric method, Beer's law was obeyed from 0.5 to 2.5 μg ml -1 for tramadol, dothiepin and 5-25 μg ml -1 for acebutolol. Using the spectrofluorimetric method linearity ranged from 0.25 to 1.25 μg ml -1 for tramadol, dothiepin and 1-5 μg ml -1 for acebutolol. Mean percentage recoveries for the spectrophotometric method were 99.68 ± 1.00, 99.95 ± 1.11 and 99.72 ± 1.01 for tramadol, acebutolol and dothiepin, respectively and for the spectrofluorimetric method, recoveries were 99.5 ± 0.844, 100.32 ± 0.969 and 99.82 ± 1.15 for the three drugs, respectively. The optimum experimental parameters for the reaction has been studied. The validity of the described procedures was assessed. Statistical analysis of the results has been carried out revealing high accuracy and good precision. The proposed methods were successfully applied for the determination of the selected drugs in their pharmaceutical preparations with good recoveries. The procedures were accurate, simple and suitable for quality control application.

  17. 50 CFR 23.17 - What are the requirements for CITES specimens traded internationally by diplomatic, consular...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 50 Wildlife and Fisheries 6 2010-10-01 2010-10-01 false What are the requirements for CITES... ENDANGERED SPECIES OF WILD FAUNA AND FLORA (CITES) Prohibitions, Exemptions, and Requirements § 23.17 What are the requirements for CITES specimens traded internationally by diplomatic, consular, military, and...

  18. [Analysis of highly cited articles published in Emergencias].

    PubMed

    Miró, Òscar; Fernández-Guerrero, Inés María; Burillo-Putze, Guillermo; Martín-Sánchez, Francisco Javier

    2015-01-01

    A journal is generally considered to be of higher quality to the extent that it publishes articles that are cited. A journal's articles are not all cited equally, however; rather, citations of only a select group of titles accounts for most of a journal's impact factor. This study aimed to identify the characteristics of Emergencias's most highly cited articles and compare their impact to that of papers by other authors in Spain, in Spanish, and internationally in the field of emergency medicine. Between 2008 and 2015, Emergencias published 975 articles, which received 2207 citations. The most-cited article received 52, and the group of 20 most-cited articles accumulated a total of 519 cites (23.5%). Even though Emergencias is published in Spanish and was included in Journal Citation Reports only recently (2008), some of the published articles have had considerable impact. The most-cited article (EVADUR Study) was in the top 2% (98th percentile) of all publications by authors in Spain, and in the top 1% of articles published in Spanish or in emergency medicine.

  19. Testing the Effectiveness of an International Conservation Agreement: Marketplace Forensics and CITES Caviar Trade Regulation

    PubMed Central

    Doukakis, Phaedra; Pikitch, Ellen K.; Rothschild, Anna; DeSalle, Rob; Amato, George; Kolokotronis, Sergios-Orestis

    2012-01-01

    Background The international wildlife trade is a key threat to biodiversity. Temporal genetic marketplace monitoring can determine if wildlife trade regulation efforts such as the Convention on International Trade in Endangered Species (CITES) are succeeding. Protected under CITES effective 1997, sturgeons and paddlefishes, the producers of black caviar, are flagship CITES species. Methodology/Principal Findings We test whether CITES has limited the amount of fraudulent black caviar reaching the marketplace. Using mitochondrial DNA-based methods, we compare mislabeling in caviar and meat purchased in the New York City area pre and post CITES listing. Our recent sampling of this market reveals a decrease in mislabeled caviar (2006–2008; 10%; n = 90) compared to pre-CITES implementation (1995–1996; 19%; n = 95). Mislabeled caviar was found only in online purchase (n = 49 online/41 retail). Conclusions/Significance Stricter controls on importing and exporting as per CITES policies may be having a positive conservation effect by limiting the amount of fraudulent caviar reaching the marketplace. Sturgeons and paddlefishes remain a conservation priority, however, due to continued overfishing and habitat degradation. Other marine and aquatic species stand to benefit from the international trade regulation that can result from CITES listing. PMID:22848410

  20. Self-citation rate and impact factor in the field of plastic and reconstructive surgery.

    PubMed

    Miyamoto, Shimpei

    2018-02-01

    Journal ranking based on the impact factor (IF) can be distorted by self-citation. The aim of this study is to investigate the present status of self-citation in the plastic surgery journals and its effect on the journals' IFs. IF, IF without self-citations (corrected IF), self-cited rate, and self-citing rate for 11 plastic surgery journals were investigated from 2009-2015, by reviewing the Journal Citation Report ® . The correlations of the IF with the self-cited rate and the self-citing rate were statistically assessed. In addition, Plastic and Reconstructive Surgery was compared with 15 top journals from other surgical specialties in 2015. IF was significantly correlated with the self-cited rate (R: 0.594, p = 0.001) and the self-citing rate (R: 0.824, p < 0.001). The self-cited rate of Plastic and Reconstructive Surgery in 2015 was higher than that of top journals from other surgical specialties. The IFs of Microsurgery and Journal of Cranio-Maxillo-Facial Surgery increased greatly in recent years, but they were inflated by high self-cited and self-citing rates. The self-citation rate positively affects the IF in plastic surgery journals. A high concentration of self-citation of some journals could distort the ranking among plastic surgery journals in general.

  1. A bibliometric analysis of pediatric liver transplantation publications.

    PubMed

    McDowell, Dermot T; Darani, Alexandre; Shun, Albert; Thomas, Gordon; Holland, Andrew J A

    2017-06-01

    Citation counts can identify landmark papers. The aim of this study was to identify and characterize the top-cited articles in the pediatric liver transplantation literature. A search strategy for the Scopus ® database was designed for pediatric liver transplantation publications from 1945 to 2014. The 50 top-cited articles were analyzed. Author co-citation analysis was performed using VOSviewer techniques. There were 2896 articles published between 1969 and 2015. The mean citation count of the top 50 cited articles was 166 (range 95-635). There were three case reports in this top-cited list. There were 15 collaborations in this top-cited list with nine being international. The top-cited publications originated in 12 countries, with the USA and the UK contributing 31 and seven articles, respectively. There were 14 authors with four or more publications in this list. There was a single author with nine publications in the top-cited list. These top-cited papers were found in 16 journals, with three journals collectively publishing over 50% of these publications. Pediatric liver transplantation research is an evolving entity. Surgical techniques and case reports are influential articles. Collaborations at a national and international level produce highly cited articles, which are found in influential journals. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  2. Measuring science-technology interactions using patent citations and author-inventor links: an exploration analysis from Chinese nanotechnology

    NASA Astrophysics Data System (ADS)

    Wang, Gangbo; Guan, Jiancheng

    2011-12-01

    This article contributes to the growing study on the interactions between science and technology with China's evidence in the field of nanotechnology, based on the database of United States Patent and Trademark Office. The analysis is focused during the period of 1991-2008, a rapid increasing period for the development of nanotechnology. Using the non-patent references cited by patents, we first investigate the science-technology connections in the context of Chinese nanotechnology, especially in institutional sectors and its application fields. Those patents, produced by academic researchers and directed towards basic scientific knowledge, generally cite more scientific references with a higher proportion of self-citations. It is interesting to find that patents contributed by collaborations between public organizations and corporations seldom contain scientific references. Following an interesting path on matching the data of publications and patents, we establish the author-inventor links in this emerging field. Author-inventors, who are co-active in publishing and patenting, are at the very top of the most prolific and highly cited researchers. Finally, we employ social network analysis to explore the characteristics of scientific and technological networks generated by co-authorship and co-invention data, to investigate the position and the role of patenting-publishing scientists in these research networks.

  3. Determination of element affinities by density fractionation of bulk coal samples

    USGS Publications Warehouse

    Querol, X.; Klika, Z.; Weiss, Z.; Finkelman, R.B.; Alastuey, A.; Juan, R.; Lopez-Soler, A.; Plana, F.; Kolker, A.; Chenery, S.R.N.

    2001-01-01

    A review has been made of the various methods of determining major and trace element affinities for different phases, both mineral and organic in coals, citing their various strengths and weaknesses. These include mathematical deconvolution of chemical analyses, direct microanalysis, sequential extraction procedures and density fractionation. A new methodology combining density fractionation with mathematical deconvolution of chemical analyses of whole coals and their density fractions has been evaluated. These coals formed part of the IEA-Coal Research project on the Modes of Occurrence of Trace Elements in Coal. Results were compared to a previously reported sequential extraction methodology and showed good agreement for most elements. For particular elements (Be, Mo, Cu, Se and REEs) in specific coals where disagreement was found, it was concluded that the occurrence of rare trace element bearing phases may account for the discrepancy, and modifications to the general procedure must be made to account for these.

  4. Radiant Heat Transfer Between Nongray Parallel Plates of Tungsten

    NASA Technical Reports Server (NTRS)

    Branstetter, J. Robert

    1961-01-01

    Net radiant heat flow between two infinite, parallel, tungsten plates was computed by summing the monochromatic energy exchange; the results are graphically presented as a function of the temperatures of the two surfaces. In general these fluxes range from approximately a to 25 percent greater than the results of gray-body computations based on the same emissivity data. The selection of spectral emissivity data and the computational procedure are discussed. The present analytical procedure is so arranged that, as spectral emissivity data for a material become available, these data can be readily introduced into the NASA data-reduction equipment, which has been programmed to compute the net heat flux for the particular geometry and basic assumptions cited in the text. Nongray-body computational techniques for determining radiant heat flux appear practical provided the combination of select spectral emissivity data and the proper mechanized data-reduction equipment are brought to bear on the problem.

  5. Citation success of different publication types: a case study on all references in psychology publications from the German-speaking countries (D-A-CH-L-L) in 2009, 2010, and 2011.

    PubMed

    Krampen, Günter; Weiland, Peter; Wiesenhütter, Jürgen

    Scientometric data on the citation success of different publication types and publication genres in psychology publications are presented. Data refer to references that are cited in these scientific publications and that are documented in PSYNDEX, the exhaustive database of psychology publications from the German-speaking countries either published in German or in English language. Firstly, data analyses refer to the references that are cited in publications of 2009 versus 2010 versus 2011. With reference to all cited references, the portion of journal articles ranges from 57 to 61 %, of books from 22 to 24 %, and of book chapters from 14 to 15 %, with a rather high stability across the three publication years analysed. Secondly, data analyses refer to the numbers of cited references from the German-speaking countries, which are also documented in PSYNDEX. These compose about 11 % of all cited references indicating that nearly 90 % of the references cited are of international and/or interdisciplinary publications not stemming from the German-speaking countries. The subsample shows the proportion of journal articles, books, and chapters, and these are very similar to the percentages identified for all references that are cited. Thirdly, analyses refer to document type, scientific genre, and psychological sub-discipline of the most frequently cited references in the psychology publications. The frequency of top-cited references of books and book chapters is almost equal to that of journal articles; two-thirds of the top-cited references are non-empirical publications, only one-third are empirical publications. Top-cited references stem particularly from clinical psychology, experimental psychology, as well as tests, testing and psychometrics. In summary, the results point to the fact that citation analyses, which are limited to journal papers, tend to neglect very high portions of references that are cited in scientific publications.

  6. The Application of Clustering Techniques to Citation Data. Research Reports Series B No. 6.

    ERIC Educational Resources Information Center

    Arms, William Y.; Arms, Caroline

    This report describes research carried out as part of the Design of Information Systems in the Social Sciences (DISISS) project. Cluster analysis techniques were applied to a machine readable file of bibliographic data in the form of cited journal titles in order to identify groupings which could be used to structure bibliographic files. Practical…

  7. Advantage of resonant power conversion in aerospace applications

    NASA Technical Reports Server (NTRS)

    Hansen, I. G.

    1983-01-01

    An ultrasonic, sinusoidal aerospace power distribution system is shown to have many advantages over other candidate power systems. These advantages include light weight, ease of fault clearing, versatility in handling many loads including motors, and the capability of production within the limits of present technology. References are cited that demonstrate the state of resonant converter technology and support these conclusions.

  8. Reasons for Selecting the University of North Dakota by New Freshmen and College Transfer Students, 1979-80.

    ERIC Educational Resources Information Center

    Nelson, Bob; Poremba, Greg

    Students' reasons for applying for admission to the University of North Dakota for the academic year 1979-80 were studied. Information was obtained from a question appearing on the admission application form completed by all new freshmen and college transfer students. Results revealed that students cited reasons related to academic program 40.2…

  9. Searching for consensus in molt terminology 11 years after Howell et al.'s "first basic problem"

    Treesearch

    Jared D. Wolfe; Erik I. Johnson; Ryan S. Terrill

    2014-01-01

    Howell et al. (2003) published an innovative augmentation to terminology proposed by Humphrey and Parkes (1959) that classified bird molt on the basis of perceived evolutionary relationships. Despite apparent universal applicability, Howell et al.’s (2003) proposed terminological changes were met with criticism that cited a failure to verify the evolutionary...

  10. 3 CFR 13525 - Executive Order 13525 of December 23, 2009. Adjustments of Certain Rates of Pay

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... President by the Constitution and the laws of the United States of America, including the laws cited herein.... Schedule 8 is effective January 1, 2010. The other schedules contained herein are effective on the first day of the first applicable pay period beginning on or after January 1, 2010. Sec. 8. Prior Order...

  11. 31 CFR 501.808 - License application and other procedures applicable to economic sanctions programs.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... procedures applicable to economic sanctions programs. 501.808 Section 501.808 Money and Finance: Treasury... procedures applicable to economic sanctions programs. Upon submission to the Office of Management and Budget..., the license application and other procedures set forth in this subpart are applicable to economic...

  12. Claims for fertility interventions: a systematic assessment of statements on UK fertility centre websites.

    PubMed

    Spencer, E A; Mahtani, K R; Goldacre, B; Heneghan, C

    2016-11-27

    Fertility services in the UK are offered by over 200 Human Fertilisation and Embryology Authority (HFEA)-registered NHS and private clinics. While in vitro fertilisation (IVF) and intracytoplasmic sperm injection (ICSI) form part of the National Institute for Health and Care Excellence (NICE) guidance, many further interventions are offered. We aimed to record claims of benefit for interventions offered by fertility centres via information on the centres' websites and record what evidence was cited for these claims. We obtained from HFEA a list of all UK centres providing fertility treatments and examined their websites. We listed fertility interventions offered in addition to standard IVF and ICSI and recorded statements about interventions that claimed or implied improvements in fertility in healthy women. We recorded which claims were quantified, and the evidence cited in support of the claims. Two reviewers extracted data from websites. We accessed websites from 21 December 2015 to 31 March 2016. We found 233 websites for HFEA-registered fertility treatment centres, of which 152 (65%) were excluded as duplicates or satellite centres, 2 were andrology clinics and 5 were unavailable or under construction websites. In total, 74 fertility centre websites, incorporating 1401 web pages, were examined for claims. We found 276 claims of benefit relating to 41 different fertility interventions made by 60 of the 74 centres (median 3 per website; range 0 to 10). Quantification was given for 79 (29%) of the claims. 16 published references were cited 21 times on 13 of the 74 websites. Many fertility centres in the UK offer a range of treatments in addition to standard IVF procedures, and for many of these interventions claims of benefit are made. In most cases, the claims are not quantified and evidence is not cited to support the claims. There is a need for more information on interventions to be made available by fertility centres, to support well-informed treatment decisions. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  13. The development of registries for surveillance of adult lead exposure, 1981 to 1992.

    PubMed

    Baser, M E

    1992-08-01

    Since 1981, 15 states have established registries for surveillance of adult lead absorption, primarily based on reports of elevated blood lead levels from clinical laboratories. I review the status of the registries and recommend steps for further development. Companies reported to the New York registry are compared with those cited by the Occupational Safety and Health Administration (OSHA). I present data on US workers and plants with potential lead exposures and blood tests, as well as review registries' reporting requirements. Registries identify many companies not cited by the Occupational Safety and Health Administration, but underreporting occurs because (1) reporting is usually not required from laboratories outside the state, (2) most registries use a blood lead reporting level of 1.21 mumol/L, which excludes many exposed workers, and (3) many companies with potential exposures do not have routine monitoring programs. Registries' reporting requirements and procedures should be standardized, including a blood lead reporting level of 0.72 mumol/L. Elevated blood lead levels should be a reportable condition nationwide, and a comprehensive national surveillance system should be established: clinical laboratories should be required to report cases to those states with lead registries or directly to the national adult lead registry.

  14. Hip arthroscopy for femoroacetabular impingement

    PubMed Central

    Nasser, Rima; Domb, Benjamin

    2018-01-01

    The purpose of this article is to give a general overview of femoroacetabular impingement (FAI) and how it could be treated arthroscopically, with some details about indications, the procedure itself and some of the complications associated with the surgery. FAI is a dynamic condition of the hip that can be a source of pain and disability and could potentially lead to arthritis. When symptomatic, and if conservative treatment fails, FAI can be addressed surgically. The goal of surgical treatment for FAI is to recreate the spherical contour of the femoral head, improve femoral offset, normalize coverage of the acetabulum, repair/reconstruct chondral damage and repair/reconstruct the labrum to restore normal mechanics and joint sealing. Advances in equipment and technique have contributed to an increase in the number of hip arthroscopy procedures performed worldwide and have made it one of the more common treatment options for symptomatic FAI. Hip arthroscopy is a procedure with an extremely steep and long learning curve. Cite this article: EFORT Open Rev 2018;3:121-129. DOI: 10.1302/2058-5241.3.170041 PMID:29780619

  15. Cultural Internationalism at the Cite Universitaire: International Education between the First and Second World Wars

    ERIC Educational Resources Information Center

    Reis, Jehnie I.

    2010-01-01

    In the 1920s, French scholars and bureaucrats created the Cite Universitaire in Paris. The institution housed university students from around the world. The Cite founders formulated a model for the Cite that reflected ideological concerns in interwar Europe with a focus on pacifism, international education and cultural internationalism. The…

  16. Treatment of adolescent sexual offenders: theory-based practice.

    PubMed

    Sermabeikian, P; Martinez, D

    1994-11-01

    The treatment of adolescent sexual offenders (ASO) has its theoretical underpinnings in social learning theory. Although social learning theory has been frequently cited in literature, a comprehensive application of this theory, as applied to practice, has not been mapped out. The social learning and social cognitive theories of Bandura appear to be particularly relevant to the group treatment of this population. The application of these theories to practice, as demonstrated in a program model, is discussed as a means of demonstrating how theory-driven practice methods can be developed.

  17. Research on combustion instability and application to solid propellant rocket motors. II.

    NASA Technical Reports Server (NTRS)

    Culick, F. E. C.

    1972-01-01

    Review of the current state of analyses of combustion instability in solid-propellant rocket motors, citing appropriate measurements and observations. The work discussed has become increasingly important, both for the interpretation of laboratory data and for predicting the transient behavior of disturbances in full-scale motors. Two central questions are considered - namely, linear stability and nonlinear behavior. Several classes of problems are discussed as special cases of a general approach to the analysis of combustion instability. Application to motors, and particularly the limitations presently understood, are stressed.

  18. Automated spectroscopic abundances of A and F-type stars using echelle spectrographs. II. Abundances of 140 A-F stars from ELODIE

    NASA Astrophysics Data System (ADS)

    Erspamer, D.; North, P.

    2003-02-01

    Using the method presented in Erspamer & North (\\cite{erspamer}, hereafter Paper I), detailed abundances of 140 stars are presented. The uncertainties characteristic of this method are presented and discussed. In particular, we show that for a S/N ratio higher than 200, the method is applicable to stars with a rotational velocity as high as 200 km s-1. There is no correlation between abundances and Vsin i, except a spurious one for Sr, Sc and Na which we explain by the small number of lines of these elements combined with a locally biased continuum. Metallic giants (Hauck \\cite{hauck}) show larger abundances than normal giants for at least 8 elements: Al, Ca, Ti, Cr, Mn, Fe, Ni and Ba. The anticorrelation for Na, Mg, Si, Ca, Fe and Ni with Vsin i suggested by Varenne & Monier (\\cite{varenne99}) is not confirmed. The predictions of the Montréal models (e.g. Richard et al. \\cite{richard01}) are not fulfilled in general. However, a correlation between left [(Fe)/(H)right ] and log g is found for stars of 1.8 to 2.0 M_sun. Various possible causes are discussed, but the physical reality of this correlation seems inescapable. Based on observations collected at the 1.93 m telescope at the Observatoire de Haute-Provence (St-Michel l'Observatoire, France) and CORALIE. Based on observations collected at the Swiss 1.2 m Leonard Euler telescopes at the European Southern Observatory (La Silla, Chile). Tables 5 and 6 are only available in electronic form at the CDS via anonymous ftp to cdsarc.u.strasbg.fr (130.79.128.5) or via http://cdsweb.u-strasbg.fr/cgi-bin/qcat?J/A+A/398/1121

  19. Microgravity science and applications. Program tasks and bibliography for FY 1994

    NASA Technical Reports Server (NTRS)

    1995-01-01

    This annual report includes research projects funded by the Office of Life and Microgravity Sciences and Applications, Microgravity Science and Applications Division, during FY 1994. It is a compilation of program tasks (objective, description, significance, progress, students funded under research, and bibliographic citations) for flight research and ground-based research in five major scientific disciplines: benchmark science, biotechnology, combustion science, fluid physics, and materials science. ATD (Advanced Technology Development) program task descriptions are also included. The bibliography cites the related PI (Principal Investigator) publications and presentations for these program tasks in FY 1994. Three appendices include Table of Acronyms, Guest Investigator Index, and Principal Investigator Index.

  20. Microgravity science & applications. Program tasks and bibliography for FY 1995

    NASA Technical Reports Server (NTRS)

    1996-01-01

    This annual report includes research projects funded by the Office of Life and Microgravity Sciences and Applications, Microgravity Science and Applications Division, during FY 1994. It is a compilation of program tasks (objective, description, significance, progress, students funded under research, and bibliographic citations) for flight research and ground based research in five major scientific disciplines: benchmark science, biotechnology, combustion science, fluid physics, and materials science. Advanced technology development (ATD) program task descriptions are also included. The bibliography cites the related principle investigator (PI) publications and presentations for these program tasks in FY 1994. Three appendices include a Table of Acronyms, a Guest Investigator index and a Principle Investigator index.

  1. When and why do doctors decide to become general practitioners? Implications for recruitment into UK general practice specialty training.

    PubMed

    Irish, Bill; Lake, Jonathan

    2011-01-01

    All applicants to round 1 of national recruitment into the general practice specialty recruitment process were surveyed as to the reasons for, and the timing of their career choices. Most applicants reported decision making after completing undergraduate training citing variety, continuity of care and work-life balance as their main drivers for a career in general practice. Applicants were statistically more likely to have undertaken a Foundation placement in general practice than their peers on a Foundation programme. Reasons for choice of deanery were largely related to location and social ties, rather than to the educational 'reputation' of its programmes.

  2. NASA patent abstracts bibliography: A continuing bibliography. Section 1: Abstracts (supplement 08)

    NASA Technical Reports Server (NTRS)

    1976-01-01

    This bibliography is issued in two sections; abstracts and indexes. The Abstract Section cites 180 patents and applications for patents introduced into the NASA scientific and technical information system during the period of July 1975 through December 1975. Each entry in the Abstract Section consists of a citation, an abstract, and in most cases, a key illustration selected from the patent or application for patent. The index Section contains entries for 2,905 patents and applications for patent citations covering the period May 1969 through December 1975. The Index Section contains five indexes -- subject, inventor, source, number and accession number.

  3. Use of Paley Classification and SUPERankle Procedure in the Management of Fibular Hemimelia.

    PubMed

    Kulkarni, Ruta M; Arora, Nitish; Saxena, Sagar; Kulkarni, Sujay M; Saini, Yadwinder; Negandhi, Rajiv

    2017-05-26

    Fibular hemimelia is the most common deficiency involving the long bones. Paley classification is based on the ankle joint morphology, identifies the basic pathology, and helps in planning the surgical management. Reconstruction surgery encompasses foot deformity correction and limb length equalization. The SUPERankle procedure is a combination of bone and soft tissue procedures that stabilizes the foot and addresses all deformities. We retrospectively reviewed 29 consecutive patients (29 limb segments), surgically treated between December 2000 and December 2014. Among the 29 patients, 27 were treated with reconstructive procedures. Type 1 (8 patients) cases were treated with only limb lengthening, and correction of tibial deformities. Type 2 (7 patients) cases were treated by distal tibial medial hemiepiphysiodesis or supramalleolar varus osteotomy. In type 3 (10 patients) cases, the foot deformity was corrected using the SUPERankle procedure. Type 4 (2 patients) cases were treated with supramalleolar osteotomy along with posteromedial release and lateral column shortening. In a second stage, limb lengthening was performed, using the Ilizarov technique. In the remaining 2 patients (type 3A and type 3C), amputation was performed using Syme technique as a first choice of treatment. The results were evaluated using Association for the Study and Application of Methods of Ilizarov scoring. Excellent results were obtained in 15 of 27 (55%) patients. Six (22%) patients had good results, 4 (14.8%) had fair results, and 2 (7%) had poor results. Mean limb length discrepancy at initial presentation was 3.55 cm (range: 2 to 5.5 cm) which significantly improved to 1.01 cm (range: 0 to 3 cm) after treatment (P=0.015). Our results and a review of the literature clearly suggest that limb reconstruction according to Paley classification, is an excellent option in the management of fibular hemimelia. Our 2-staged procedure (SUPERankle procedure followed by limb lengthening) helps in reducing the complications of limb lengthening and incidence of ankle stiffness. Performing the first surgery at an earlier age (below 5 y) plays a significant role in preventing recurrent foot deformities. Level IV.This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0/.

  4. CITED2 silencing sensitizes cancer cells to cisplatin by inhibiting p53 trans-activation and chromatin relaxation on the ERCC1 DNA repair gene

    PubMed Central

    Liu, Yu-Chin; Chang, Pu-Yuan; Chao, Chuck C.-K.

    2015-01-01

    In this study, we show that silencing of CITED2 using small-hairpin RNA (shCITED2) induced DNA damage and reduction of ERCC1 gene expression in HEK293, HeLa and H1299 cells, even in the absence of cisplatin. In contrast, ectopic expression of ERCC1 significantly reduced intrinsic and induced DNA damage levels, and rescued the effects of CITED2 silencing on cell viability. The effects of CITED2 silencing on DNA repair and cell death were associated with p53 activity. Furthermore, CITED2 silencing caused severe elimination of the p300 protein and markers of relaxed chromatin (acetylated H3 and H4, i.e. H3K9Ac and H3K14Ac) in HEK293 cells. Chromatin immunoprecipitation assays further revealed that DNA damage induced binding of p53 along with H3K9Ac or H3K14Ac at the ERCC1 promoter, an effect which was almost entirely abrogated by silencing of CITED2 or p300. Moreover, lentivirus-based CITED2 silencing sensitized HeLa cell line-derived tumor xenografts to cisplatin in immune-deficient mice. These results demonstrate that CITED2/p300 can be recruited by p53 at the promoter of the repair gene ERCC1 in response to cisplatin-induced DNA damage. The CITED2/p300/p53/ERCC1 pathway is thus involved in the cell response to cisplatin and represents a potential target for cancer therapy. PMID:26384430

  5. On the advancement of highly cited research in China: An analysis of the Highly Cited database.

    PubMed

    Li, John Tianci

    2018-01-01

    This study investigates the progress of highly cited research in China from 2001 to 2016 through the analysis of the Highly Cited database. The Highly Cited database, compiled by Clarivate Analytics, is comprised of the world's most influential researchers in the 22 Essential Science Indicator fields as catalogued by the Web of Science. The database is considered an international standard for the measurement of national and institutional highly cited research output. Overall, we found a consistent and substantial increase in Highly Cited Researchers from China during the timespan. The Chinese institutions with the most Highly Cited Researchers- the Chinese Academy of Sciences, Tsinghua University, Peking University, Zhejiang University, the University of Science and Technology of China, and BGI Shenzhen- are all top ten universities or primary government research institutions. Further evaluation of separate fields of research and government funding data from the National Natural Science Foundation of China revealed disproportionate growth efficiencies among the separate divisions of the National Natural Science Foundation. The most development occurred in the fields of Chemistry, Materials Sciences, and Engineering, whereas the least development occurred in Economics and Business, Health Sciences, and Life Sciences.

  6. Citations of Brazilian physical therapy journals in national publications.

    PubMed

    Teixeira, Renan K C; Yamaki, Vitor N; Botelho, Nara M; Teixeira, Renato C

    2014-01-01

    Quotations in Brazilian journals are mainly obtained from national articles (articles from Brazilian journals); thus, it is essential to determine how frequently these articles reference Brazilian journals. This study sought to verify how frequently national papers are cited in the references of three Brazilian physical therapy journals. All references for articles published in Fisioterapia em Movimento, Fisioterapia e Pesquisa and Revista Brasileira de Fisioterapia between 2010 and 2012 were evaluated. In particular, the numbers of national articles and international articles (articles from international journals) cited in these references were determined. A total of 13,009 references cited by 456 articles were analyzed, and 2,924 (22.47%) of the cited works were national articles. There were no significant differences among the three examined years. A total of 36 (7.89%) articles did not cite national articles, whereas 65 (13.25%) articles cited more national articles than international articles. On average, 22.47% of the works cited by the evaluated articles were national articles. No significant differences were detected among the three analyzed years.

  7. Journal article citation classics in school psychology: analysis of the most cited articles in five school psychology journals.

    PubMed

    Price, Katherine W; Floyd, Randy G; Fagan, Thomas K; Smithson, Kelly

    2011-12-01

    The purpose of this study was to identify and examine the top 100 most highly cited articles of all time as well as the 25 most highly cited articles of the last decade from within 5 school psychology journals: Journal of School Psychology, Psychology in the Schools, School Psychology International, School Psychology Quarterly, and School Psychology Review. The Institute for Scientific Information Web of Science database was utilized to identify citation counts for each article appearing in these journals. Coding schemes were used to identify article type and content area. The top 10 most highly cited articles of all time as well as the top 10 most highly cited articles of the past decade are detailed, and general patterns found across these articles are discussed. Implications for reviewing manuscripts that are likely to become highly cited articles and for authoring a highly cited article are offered. Copyright © 2011. Published by Elsevier Ltd.

  8. The MMI Semantic Framework: Rosetta Stones for Earth Sciences

    NASA Astrophysics Data System (ADS)

    Rueda, C.; Bermudez, L. E.; Graybeal, J.; Alexander, P.

    2009-12-01

    Semantic interoperability—the exchange of meaning among computer systems—is needed to successfully share data in Ocean Science and across all Earth sciences. The best approach toward semantic interoperability requires a designed framework, and operationally tested tools and infrastructure within that framework. Currently available technologies make a scientific semantic framework feasible, but its development requires sustainable architectural vision and development processes. This presentation outlines the MMI Semantic Framework, including recent progress on it and its client applications. The MMI Semantic Framework consists of tools, infrastructure, and operational and community procedures and best practices, to meet short-term and long-term semantic interoperability goals. The design and prioritization of the semantic framework capabilities are based on real-world scenarios in Earth observation systems. We describe some key uses cases, as well as the associated requirements for building the overall infrastructure, which is realized through the MMI Ontology Registry and Repository. This system includes support for community creation and sharing of semantic content, ontology registration, version management, and seamless integration of user-friendly tools and application programming interfaces. The presentation describes the architectural components for semantic mediation, registry and repository for vocabularies, ontology, and term mappings. We show how the technologies and approaches in the framework can address community needs for managing and exchanging semantic information. We will demonstrate how different types of users and client applications exploit the tools and services for data aggregation, visualization, archiving, and integration. Specific examples from OOSTethys (http://www.oostethys.org) and the Ocean Observatories Initiative Cyberinfrastructure (http://www.oceanobservatories.org) will be cited. Finally, we show how semantic augmentation of web services standards could be performed using framework tools.

  9. [Literature cited in a study of Yugoslav biomedical journals].

    PubMed

    Brkić, S; Pejić, M; Cikić, B

    1995-01-01

    The paper reviews results of a research on literature cited in papers published in two most remarkable Yugoslav biomedical journals, Medicinski Pregled and Srpski arhiv za celokupno lekarstvo, in 1985 and 1992. The analysis included the following parameters: the amount of published papers, the quantity of cites out of the literature that has been used, frequency of citation of foreign and domestic literature as well as the quantity of self citations. According to the gathered results, foreign literature is remarkably more often cited than the domestic references, mostly in English, but the percentage of citing one's own papers is also high.

  10. Assessing the Downstream Impact of the Integrated Use of Socioeconomic and Remote Sensing Data

    NASA Astrophysics Data System (ADS)

    Chen, R. S.; Downs, R. R.; Schumacher, J.

    2014-12-01

    The interdisciplinary use of data from multiple disciplines to address both research and applied problems has received increasing attention in the sciences, but understanding remains limited on the specific modalities of data use and their impact not only in enabling new research insights but also in facilitating the application of research to societal problems. In our previous work, we used citation analysis to investigate the use of data from the NASA Socioeconomic Data and Applications Center (SEDAC) and identify the extent of interdisciplinary use, based on the subject classifications of citing journals. We also proposed and tested a taxonomy of data integration and use on a selection of peer-reviewed scientific articles that cited both remote sensing data and socioeconomic data from SEDAC. We extend both of these analyses here. We analyze the interdisciplinary use of SEDAC data over a seven-year period including the types and topical areas of application observed. We also explore the degree to which different types of data integration and use are leading to further "downstream" research and applications, and if objective measures can be developed using bibliometric methods to quantify downstream use and impact in meaningful ways. These methods include both traditional citation analysis and searches of the informal literature and online resources. Better understanding of how disparate data and information has been utilized to address new interdisciplinary problems will help the data user and provider communities improve the effectiveness and efficiency of their efforts. It should also provide justification for further investments in linking different data resources and networks across scientific fields, in methods of interdisciplinary data integration, and in application of integrated data to societal problems.

  11. Secondary and Tertiary Citing: A Study of Referencing Behavior in the Literature of Citation Analysis Deriving from the Ortega Hypothesis of Cole and Cole.

    ERIC Educational Resources Information Center

    Hoerman, Heidi Lee; Nowicke, Carole Elizabeth

    1995-01-01

    Examines documents and citations relating to literature of the Ortega Hypothesis, reviews citing behaviors and errors of individual citations, and includes analysis of the occurrences of secondary and tertiary citing. Findings show there is little evidence to prove that secondary and tertiary citing is not occurring and suggests that further…

  12. 24 CFR 50.19 - Categorical exclusions not subject to the Federal laws and authorities cited in § 50.4.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... to the Federal laws and authorities cited in § 50.4. 50.19 Section 50.19 Housing and Urban... to the Federal laws and authorities cited in § 50.4. (a) General. The activities and related... individual compliance requirements of the Federal laws and authorities cited in § 50.4, unless otherwise...

  13. 24 CFR 50.19 - Categorical exclusions not subject to the Federal laws and authorities cited in § 50.4.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... to the Federal laws and authorities cited in § 50.4. 50.19 Section 50.19 Housing and Urban... to the Federal laws and authorities cited in § 50.4. (a) General. The activities and related... individual compliance requirements of the Federal laws and authorities cited in § 50.4, unless otherwise...

  14. 24 CFR 50.19 - Categorical exclusions not subject to the Federal laws and authorities cited in § 50.4.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... to the Federal laws and authorities cited in § 50.4. 50.19 Section 50.19 Housing and Urban... to the Federal laws and authorities cited in § 50.4. (a) General. The activities and related... individual compliance requirements of the Federal laws and authorities cited in § 50.4, unless otherwise...

  15. 47 CFR 1.926 - Application processing; initial procedures.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 1 2011-10-01 2011-10-01 false Application processing; initial procedures. 1.926 Section 1.926 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL PRACTICE AND PROCEDURE Wireless Radio Services Applications and Proceedings Application Requirements and Procedures § 1.926...

  16. 47 CFR 1.926 - Application processing; initial procedures.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 1 2010-10-01 2010-10-01 false Application processing; initial procedures. 1.926 Section 1.926 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL PRACTICE AND PROCEDURE Wireless Radio Services Applications and Proceedings Application Requirements and Procedures § 1.926...

  17. Critical care procedure logging using handheld computers

    PubMed Central

    Carlos Martinez-Motta, J; Walker, Robin; Stewart, Thomas E; Granton, John; Abrahamson, Simon; Lapinsky, Stephen E

    2004-01-01

    Introduction We conducted this study to evaluate the feasibility of implementing an internet-linked handheld computer procedure logging system in a critical care training program. Methods Subspecialty trainees in the Interdepartmental Division of Critical Care at the University of Toronto received and were trained in the use of Palm handheld computers loaded with a customized program for logging critical care procedures. The procedures were entered into the handheld device using checkboxes and drop-down lists, and data were uploaded to a central database via the internet. To evaluate the feasibility of this system, we tracked the utilization of this data collection system. Benefits and disadvantages were assessed through surveys. Results All 11 trainees successfully uploaded data to the central database, but only six (55%) continued to upload data on a regular basis. The most common reason cited for not using the system pertained to initial technical problems with data uploading. From 1 July 2002 to 30 June 2003, a total of 914 procedures were logged. Significant variability was noted in the number of procedures logged by individual trainees (range 13–242). The database generated by regular users provided potentially useful information to the training program director regarding the scope and location of procedural training among the different rotations and hospitals. Conclusion A handheld computer procedure logging system can be effectively used in a critical care training program. However, user acceptance was not uniform, and continued training and support are required to increase user acceptance. Such a procedure database may provide valuable information that may be used to optimize trainees' educational experience and to document clinical training experience for licensing and accreditation. PMID:15469577

  18. Concentration of the Most-Cited Papers in the Scientific Literature: Analysis of Journal Ecosystems

    PubMed Central

    Ioannidis, John P. A.

    2006-01-01

    Background A minority of scientific journals publishes the majority of scientific papers and receives the majority of citations. The extent of concentration of the most influential articles is less well known. Methods/Principal Findings The 100 most-cited papers in the last decade in each of 21 scientific fields were analyzed; fields were considered as ecosystems and their “species” (journal) diversity was evaluated. Only 9% of journals in Journal Citation Reports had published at least one such paper. Among this 9%, half of them had published only one such paper. The number of journals that had published a larger number of most-cited papers decreased exponentially according to a Lotka law. Except for three scientific fields, six journals accounted for 53 to 94 of the 100 most-cited papers in their field. With increasing average number of citations per paper (citation density) in a scientific field, concentration of the most-cited papers in a few journals became even more prominent (p<0.001). Concentration was unrelated to the number of papers published or number of journals available in a scientific field. Multidisciplinary journals accounted for 24% of all most-cited papers, with large variability across fields. The concentration of most-cited papers in multidisciplinary journals was most prominent in fields with high citation density (correlation coefficient 0.70, p<0.001). Multidisciplinary journals had published fewer than eight of the 100 most-cited papers in eight scientific fields (none in two fields). Journals concentrating most-cited original articles often differed from those concentrating most-cited reviews. The concentration of the most-influential papers was stronger than the already prominent concentration of papers published and citations received. Conclusions Despite a plethora of available journals, the most influential papers are extremely concentrated in few journals, especially in fields with high citation density. Existing multidisciplinary journals publish selectively most-cited papers from fields with high citation density. PMID:17183679

  19. Fertility preservation in pediatric and adolescent cancer patients in Switzerland: A qualitative cross-sectional survey.

    PubMed

    Diesch, Tamara; von der Weid, Nicolas Xavier; Szinnai, Gabor; Schaedelin, Sabine; De Geyter, Christian; Rovó, Alicia

    2016-10-01

    Fertility preservation (FP) is an important topic of discussion in the field of oncology, particularly in pediatric oncology. Despite the awareness of severe impact of infertility on quality of life and different guidelines available in this area, the options in FP are not routinely discussed with the pediatric cancer patients and their parents. To the best of our knowledge, this is the first survey report concerned to FP counseling and procedures in pediatric and adolescent cancer patients in Switzerland. This survey was conducted from June 2014 to October 2014 on the counseling and procedures performed between 2009 and 2013; the questionnaire was completed by one of the professional from hematology/oncology centers in Switzerland. Currently, only four out of nine centers have a program for FP. In 2013, 45/301 (15%) patients received FP counseling and 36/301 (12%) underwent an FP procedure. The most commonly performed procedures from 2009 to 2013 were administration of gonadotropin releasing hormone agonist (3%) and cryopreservation of ovarian tissue in females (3%) and cryopreservation of sperms in males (6%); the most frequently cited reason for the absence of FP counseling was lack of time (55%). Therefore, this survey should help to develop and harmonize practices with respect to FP counseling and procedures in Switzerland, and to establish FP as a standard of care during cancer treatment. Copyright © 2016. Published by Elsevier Ltd.

  20. EXAMINING EVIDENCE IN U.S. PAYER COVERAGE POLICIES FOR MULTI-GENE PANELS AND SEQUENCING TESTS

    PubMed Central

    Chambers, James D.; Saret, Cayla J.; Anderson, Jordan E.; Deverka, Patricia A.; Douglas, Michael P.; Phillips, Kathryn A.

    2017-01-01

    Objectives The aim of this study was to examine the evidence payers cited in their coverage policies for multi-gene panels and sequencing tests (panels), and to compare these findings with the evidence payers cited in their coverage policies for other types of medical interventions. Methods We used the University of California at San Francisco TRANSPERS Payer Coverage Registry to identify coverage policies for panels issued by five of the largest US private payers. We reviewed each policy and categorized the evidence cited within as: clinical studies, systematic reviews, technology assessments, cost-effectiveness analyses (CEAs), budget impact studies, and clinical guidelines. We compared the evidence cited in these coverage policies for panels with the evidence cited in policies for other intervention types (pharmaceuticals, medical devices, diagnostic tests and imaging, and surgical interventions) as reported in a previous study. Results Fifty-five coverage policies for panels were included. On average, payers cited clinical guidelines in 84 percent of their coverage policies (range, 73–100 percent), clinical studies in 69 percent (50–87 percent), technology assessments 47 percent (33–86 percent), systematic reviews or meta-analyses 31 percent (7–71 percent), and CEAs 5 percent (0–7 percent). No payers cited budget impact studies in their policies. Payers less often cited clinical studies, systematic reviews, technology assessments, and CEAs in their coverage policies for panels than in their policies for other intervention types. Payers cited clinical guidelines in a comparable proportion of policies for panels and other technology types. Conclusions Payers in our sample less often cited clinical studies and other evidence types in their coverage policies for panels than they did in their coverage policies for other types of medical interventions. PMID:29065945

  1. CITED1 Expression in Liver Development and Hepatoblastoma12

    PubMed Central

    Murphy, Andrew J; de Caestecker, Christian; Pierce, Janene; Boyle, Scott C; Ayers, Gregory D; Zhao, Zhiguo; Libes, Jaime M; Correa, Hernan; Walter, Teagan; Huppert, Stacey S; Perantoni, Alan O; de Caestecker, Mark P; Lovvorn, Harold N

    2012-01-01

    Hepatoblastoma, the most common pediatric liver cancer, consists of epithelial mixed embryonal/fetal (EMEF) and pure fetal histologic subtypes, with the latter exhibiting a more favorable prognosis. Few embryonal histology markers that yield insight into the biologic basis for this prognostic discrepancy exist. CBP/P-300 interacting transactivator 1 (CITED1), a transcriptional co-activator, is expressed in the self-renewing nephron progenitor population of the developing kidney and broadly in its malignant analog, Wilms tumor (WT). In this current study, CITED1 expression is detected in mouse embryonic liver initially on post-coitum day 10.5 (e10.5), begins to taper by e14.5, and is undetectable in e18.5 and adult livers. CITED1 expression is detected in regenerating murine hepatocytes following liver injury by partial hepatectomy and 3,5-diethoxycarbonyl-1,4-dihydrocollidine. Importantly, while CITED1 is undetectable in normal human adult livers, 36 of 41 (87.8%) hepatoblastoma specimens express CITED1, where it is enriched in EMEF specimens compared to specimens of pure fetal histology. CITED1 overexpression in Hep293TT human hepatoblastoma cells induces cellular proliferation and upregulates the Wnt inhibitors Kringle containing transmembrane protein 1 (KREMEN1) and CXXC finger protein 4 (CXXC4). CITED1 mRNA expression correlates with expression of CXXC4 and KREMEN1 in clinical hepatoblastoma specimens. These data show that CITED1 is expressed during a defined time course of liver development and is no longer expressed in the adult liver but is upregulated in regenerating hepatocytes following liver injury. Moreover, as in WT, this embryonic marker is reexpressed in hepatoblastoma and correlates with embryonal histology. These findings identify CITED1 as a novel marker of hepatic progenitor cells that is re-expressed following liver injury and in embryonic liver tumors. PMID:23308048

  2. EXAMINING EVIDENCE IN U.S. PAYER COVERAGE POLICIES FOR MULTI-GENE PANELS AND SEQUENCING TESTS.

    PubMed

    Chambers, James D; Saret, Cayla J; Anderson, Jordan E; Deverka, Patricia A; Douglas, Michael P; Phillips, Kathryn A

    2017-01-01

    The aim of this study was to examine the evidence payers cited in their coverage policies for multi-gene panels and sequencing tests (panels), and to compare these findings with the evidence payers cited in their coverage policies for other types of medical interventions. We used the University of California at San Francisco TRANSPERS Payer Coverage Registry to identify coverage policies for panels issued by five of the largest US private payers. We reviewed each policy and categorized the evidence cited within as: clinical studies, systematic reviews, technology assessments, cost-effectiveness analyses (CEAs), budget impact studies, and clinical guidelines. We compared the evidence cited in these coverage policies for panels with the evidence cited in policies for other intervention types (pharmaceuticals, medical devices, diagnostic tests and imaging, and surgical interventions) as reported in a previous study. Fifty-five coverage policies for panels were included. On average, payers cited clinical guidelines in 84 percent of their coverage policies (range, 73-100 percent), clinical studies in 69 percent (50-87 percent), technology assessments 47 percent (33-86 percent), systematic reviews or meta-analyses 31 percent (7-71 percent), and CEAs 5 percent (0-7 percent). No payers cited budget impact studies in their policies. Payers less often cited clinical studies, systematic reviews, technology assessments, and CEAs in their coverage policies for panels than in their policies for other intervention types. Payers cited clinical guidelines in a comparable proportion of policies for panels and other technology types. Payers in our sample less often cited clinical studies and other evidence types in their coverage policies for panels than they did in their coverage policies for other types of medical interventions.

  3. Antimatter. (Latest citations from the INSPEC database). Published Search

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    1996-01-01

    The bibliography contains citations concerning physical theory, testing, and practical applications of antimatter. Related nuclear phenomena, matter-antimatter interactions, relativity, antigravity, formation of the universe, and space-time configurations are described. The roles of cosmic rays, black holes, antiprotons, and positrons are discussed. Antimatter propulsion spacecraft are briefly cited. (Contains 50-250 citations and includes a subject term index and title list.) (Copyright NERAC, Inc. 1995)

  4. Antimatter. (Latest citations from the INSPEC database). Published Search

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1994-12-01

    The bibliography contains citations concerning physical theory, testing, and practical applications of antimatter. Related nuclear phenomena, matter-antimatter interactions, relativity, antigravity, formation of the universe, and space-time configurations are described. The roles of cosmic rays, black holes, antiprotons, and positrons are discussed. Antimatter propulsion spacecraft are briefly cited. (Contains a minimum of 182 citations and includes a subject term index and title list.)

  5. Resource Letter: LBOT-1: Laser-based optical tweezers

    PubMed Central

    Lang, Matthew J.; Block, Steven M.

    2006-01-01

    This Resource Letter provides a guide to the literature on optical tweezers, also known as laser-based, gradient-force optical traps. Journal articles and books are cited for the following main topics: general papers on optical tweezers, trapping instrument design, optical detection methods, optical trapping theory, mechanical measurements, single molecule studies, and sections on biological motors, cellular measurements and additional applications of optical tweezers. PMID:16971965

  6. Resource Letter: LBOT-1: Laser-based optical tweezers.

    PubMed

    Lang, Matthew J; Block, Steven M

    2003-03-01

    This Resource Letter provides a guide to the literature on optical tweezers, also known as laser-based, gradient-force optical traps. Journal articles and books are cited for the following main topics: general papers on optical tweezers, trapping instrument design, optical detection methods, optical trapping theory, mechanical measurements, single molecule studies, and sections on biological motors, cellular measurements and additional applications of optical tweezers.

  7. Bibliography of Lewis Research Center technical publications announced in 1977

    NASA Technical Reports Server (NTRS)

    1978-01-01

    This compilation of abstracts describes and indexes over 780 technical reports resulting from the scientific and engineering work performed and managed by the Lewis Research Center in 1977. All the publications were announced in the 1977 issues of STAR (Scientific and Technical Aerospace Reports) and/or IAA (International Aerospace Abstracts). Documents cited include research reports, journal articles, conference presentations, patents and patent applications, and theses.

  8. Nanophotonic Devices in Silicon for Nonlinear Optics

    DTIC Science & Technology

    2010-10-15

    record performance  Demonstration of world‟s lowest loss slot waveguides, made in a DOD-trusted foundry (BAE Systems)  Design study showing...highly-cited design study.  Design study on analog links using the above modulators.  Demonstration of the first silicon waveguides for the mid...Hochberg. Design of transmission line driven slot waveguide Mach-Zehnder interferometers and application to analog optical links. Optics Express 2010

  9. Bibliography of Lewis Research Center technical publications announced in 1983

    NASA Technical Reports Server (NTRS)

    1984-01-01

    This compilation of abstracts describes and indexes over 800 technical publications that resulted from the scientific and engineering work performed and managed by the Lewis Research Center in 1983. Announced in the 1983 issues of STAR (Scientific and Technical Aerospace Reports) and/or IAA (International Aerospace Abstracts), the documents cited include research reports, journal articles, conference presentations, patents and patent applications, and theses.

  10. 47 CFR 22.131 - Procedures for mutually exclusive applications.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... SERVICES PUBLIC MOBILE SERVICES Licensing Requirements and Procedures Applications and Notifications § 22... procedures in this section for processing mutually exclusive applications in the Public Mobile Services... 47 Telecommunication 2 2010-10-01 2010-10-01 false Procedures for mutually exclusive applications...

  11. Malpractice in otology.

    PubMed

    Blake, Danielle M; Svider, Peter F; Carniol, Eric T; Mauro, Andrew C; Eloy, Jean Anderson; Jyung, Robert W

    2013-10-01

    (1) Analyze otologic procedural malpractice litigation in the United States of America. (2) Discuss ways to prevent future malpractice litigation. Case series with record review. The study is a case series with review of court records pertaining to otologic procedures using the Westlaw legal database. The phrase medical malpractice was searched with terms related to otology and neurotology obtained from the AAO-HNS website. Of the 47 claims that met inclusion criteria, 63.8% were decided in the physician's favor, 25.5% were decided in the plaintiff's favor (average payment $446,697), and 10.6% were settled out of court (average payment $372,607). Cerumen removal was the most common procedure leading to complaint (21.3%) and the most likely procedure to lead to payment (50.0%). Hearing loss was the most common injury claimed among all cases (53.2%) and resulted in a high proportion of cases that led to payment (40.0%). Other common alleged injuries were facial nerve injury (27.7%), tympanic membrane perforation (23.4%), need for additional surgery (42.6%), and lack of informed consent (31.9%). In addition, cases resulting from acoustic neuroma or stapedectomy resulted in higher payments to the plaintiffs (average $3,498,597 and $2,733,000, respectively). Malpractice trials were resolved in the defendant's favor in the majority of cases. Cerumen removal was the most common procedure leading to complaint and the procedure most likely to result in payment. Hearing loss was the most common injury cited. Payment was highest in acoustic neuroma and stapedectomy cases.

  12. The Top-100 Most-Cited Articles on Meningioma.

    PubMed

    Almutairi, Othman; Albakr, Abdulrahman; Al-Habib, Amro; Ajlan, Abdulrazag

    2017-11-01

    There is an abundance of articles published on meningioma. To identify the 100 most-cited articles on meningioma and to perform a bibliometric analysis. In November 2016, we performed a title-specific search of the Scopus database using "meningioma" as our search query term without publication date restrictions. The top 100 most cited articles were obtained and reviewed. The top 100 most cited articles received a mean 198 citations per paper. Publication dates ranged from 1953 to 2013; most articles were published between 1994 and 2003, with 50 articles published during that period. NEUROSURGERY published the greatest number of top cited articles (22 of 100). The most frequent study categories were laboratorial studies (31 of 100) and natural history studies (28 of 100). Nonoperative management studies were twice as common as operative management studies in the top-cited articles. Neurosurgery as a specialty contributed to 50% of the top 100 list. The most contributing institute was the Mayo Clinic (11%); the majority of the top cited articles originated in the United States (53%). We identified the top 100 most-cited articles on meningioma that may be considered significant and impactful works, as well as the most noteworthy. In addition, we recognized the historical development and advances in meningioma research and the important contributions of various authors, specialty fields, and countries. A large proportion of the most cited articles were written by authors other than neurosurgeons, and many of these articles were published in non-neurosurgery journals. Copyright © 2017 Elsevier Inc. All rights reserved.

  13. Partial rescue of defects in Cited2-deficient embryos by HIF-1alpha heterozygosity.

    PubMed

    Xu, Bing; Doughman, Yongqiu; Turakhia, Mona; Jiang, Weihong; Landsettle, Chad E; Agani, Faton H; Semenza, Gregg L; Watanabe, Michiko; Yang, Yu-Chung

    2007-01-01

    Hypoxia inducible factor-1 (HIF-1) initiates key cellular and tissue responses to physiological and pathological hypoxia. Evidence from in vitro and structural analyses supports a critical role for Cited2 in down-regulating HIF-1-mediated transcription by competing for binding with oxygen-sensitive HIF-1alpha to transcriptional co-activators CBP/p300. We previously detected elevated expression of HIF-1 target genes in Cited2(-/-) embryonic hearts, indicating that Cited2 inhibits HIF-1 transactivation in vivo. In this study, we show for the first time that highly hypoxic cardiac regions in mouse embryos corresponded to the sites of defects in Cited2(-/-) embryos and that defects of the outflow tract, interventricular septum, cardiac vasculature, and hyposplenia were largely rescued by HIF-1alpha haploinsufficiency. The hypoxia of the outflow tract and interventricular septum peaked at E13.5 and dissipated by E15.5 in wild-type hearts, but persisted in E15.5 Cited2(-/-) hearts. The persistent hypoxia and abnormal vasculature in the myocardium of interventricular septum in E15.5 Cited2(-/-) hearts were rescued with decreased HIF-1alpha gene dosage. Accordingly, mRNA levels of HIF-1-responsive genes were reduced in Cited2(-/-) embryonic hearts by HIF-1alpha heterozygosity. These findings suggest that a precise level of HIF-1 transcriptional activity critical for normal development is triggered by differential hypoxia and regulated through feedback inhibition by Cited2.

  14. The (lack of) impact of retraction on citation networks.

    PubMed

    Madlock-Brown, Charisse R; Eichmann, David

    2015-02-01

    Article retraction in research is rising, yet retracted articles continue to be cited at a disturbing rate. This paper presents an analysis of recent retraction patterns, with a unique emphasis on the role author self-cites play, to assist the scientific community in creating counter-strategies. This was accomplished by examining the following: (1) A categorization of retracted articles more complete than previously published work. (2) The relationship between citation counts and after-retraction self-cites from the authors of the work, and the distribution of self-cites across our retraction categories. (3) The distribution of retractions written by both the author and the editor across our retraction categories. (4) The trends for seven of our nine defined retraction categories over a 6-year period. (5) The average journal impact factor by category, and the relationship between impact factor, author self-cites, and overall citations. Our findings indicate new reasons for retractions have emerged in recent years, and more editors are penning retractions. The rates of increase for retraction varies by category, and there is statistically significant difference of average impact factor between many categories. 18 % of authors self-cite retracted work post retraction with only 10 % of those authors also citing the retraction notice. Further, there is a positive correlation between self-cites and after retraction citations.

  15. Physiological loading of joints prevents cartilage degradation through CITED2.

    PubMed

    Leong, Daniel J; Li, Yong H; Gu, Xiang I; Sun, Li; Zhou, Zuping; Nasser, Philip; Laudier, Damien M; Iqbal, Jameel; Majeska, Robert J; Schaffler, Mitchell B; Goldring, Mary B; Cardoso, Luis; Zaidi, Mone; Sun, Hui B

    2011-01-01

    Both overuse and disuse of joints up-regulate matrix metalloproteinases (MMPs) in articular cartilage and cause tissue degradation; however, moderate (physiological) loading maintains cartilage integrity. Here, we test whether CBP/p300-interacting transactivator with ED-rich tail 2 (CITED2), a mechanosensitive transcriptional coregulator, mediates this chondroprotective effect of moderate mechanical loading. In vivo, hind-limb immobilization of Sprague-Dawley rats up-regulates MMP-1 and causes rapid, histologically detectable articular cartilage degradation. One hour of daily passive joint motion prevents these changes and up-regulates articular cartilage CITED2. In vitro, moderate (2.5 MPa, 1 Hz) intermittent hydrostatic pressure (IHP) treatment suppresses basal MMP-1 expression and up-regulates CITED2 in human chondrocytes, whereas high IHP (10 MPa) down-regulates CITED2 and increases MMP-1. Competitive binding and transcription assays demonstrate that CITED2 suppresses MMP-1 expression by competing with MMP transactivator, Ets-1 for its coactivator p300. Furthermore, CITED2 up-regulation in vitro requires the p38δ isoform, which is specifically phosphorylated by moderate IHP. Together, these studies identify a novel regulatory pathway involving CITED2 and p38δ, which may be critical for the maintenance of articular cartilage integrity under normal physical activity levels.

  16. The Most-Cited Works in Severe Traumatic Brain Injury: A Bibliometric Analysis of the 100 Most-Cited Articles.

    PubMed

    Li, Lei; Ma, Xiaoye; Pandey, Sajan; Deng, Xianyu; Chen, Songyu; Cui, Daming; Gao, Liang

    2018-05-01

    There is an abundance of works published on severe traumatic brain injury (sTBI). Bibliometric analyses aim to provide a macroscopic view of research activities regarding sTBI and are helpful in determining the most impactful studies within this field. We performed a generalized search using the database of Web of Science, organized the references by the number of citations, and reviewed full length-articles for the top-100 most-cited articles on sTBI. The articles were classified according to focus. The top-100 articles were cited on average 326.4 times per paper. The Journal of Neurosurgery published the greatest number of top-100 cited articles (9 of 100). Authors from the United States published the majority (67%) of the most-cited articles. The most popular categories were "reviews and guidelines" and "etiology and epidemiology." The present study provides a cross-sectional summary of the 100 most-cited articles on sTBI, highlighting areas of research needing further investigation and development. Copyright © 2018 Elsevier Inc. All rights reserved.

  17. Citations of Brazilian physical therapy journals in national publications

    PubMed Central

    Teixeira, Renan K. C.; Yamaki, Vitor N.; Botelho, Nara M.; Teixeira, Renato C.

    2014-01-01

    Background Quotations in Brazilian journals are mainly obtained from national articles (articles from Brazilian journals); thus, it is essential to determine how frequently these articles reference Brazilian journals. Objective This study sought to verify how frequently national papers are cited in the references of three Brazilian physical therapy journals. Method All references for articles published in Fisioterapia em Movimento, Fisioterapia e Pesquisa and Revista Brasileira de Fisioterapia between 2010 and 2012 were evaluated. In particular, the numbers of national articles and international articles (articles from international journals) cited in these references were determined. Results A total of 13,009 references cited by 456 articles were analyzed, and 2,924 (22.47%) of the cited works were national articles. There were no significant differences among the three examined years. A total of 36 (7.89%) articles did not cite national articles, whereas 65 (13.25%) articles cited more national articles than international articles. Conclusion On average, 22.47% of the works cited by the evaluated articles were national articles. No significant differences were detected among the three analyzed years. PMID:24675917

  18. Functional Analyses of a Novel CITED2 Nonsynonymous Mutation in Chinese Tibetan Patients with Congenital Heart Disease.

    PubMed

    Liu, Shiming; Su, Zhaobing; Tan, Sainan; Ni, Bin; Pan, Hong; Liu, Beihong; Wang, Jing; Xiao, Jianmin; Chen, Qiuhong

    2017-08-01

    CITED2 gene is an important cardiac transcription factor that plays a fundamental role in the formation and development of embryonic cardiovascular. Previous studies have showed that knock-out of CITED2 in mice might result in various cardiac malformations. However, the mechanisms of CITED2 mutation on congenital heart disease (CHD) in Chinese Tibetan population are still poorly understood. In the present study, 187 unrelated Tibetan patients with CHD and 200 unrelated Tibetan healthy controls were screened for variants in the CITED2 gene; we subsequently identified one potential disease-causing mutation p.G143A in a 6-year-old girl with PDA and functional analyses of the mutation were carried out. Our study showed that the novel mutation of CITED2 significantly enhanced the expression activity of vascular endothelial growth factor (VEGF) under the role of co-receptor hypoxia inducible factor 1-aipha (HIF-1A), which is closely related with embryonic cardiac development. As a result, CITED2 gene mutation may play a significant role in the development of pediatric congenital heart disease.

  19. Bioavailability of Plant-Derived Antioxidants

    PubMed Central

    Abourashed, Ehab A.

    2013-01-01

    Natural products with antioxidant properties have been extensively utilized in the pharmaceutical and food industry and have also been very popular as health-promoting herbal products. This review provides a summary of the literature published around the first decade of the 21st century regarding the oral bioavailability of carotenoids, polyphenols and sulfur compounds as the three major classes of plant-derived antioxidants. The reviewed original research includes more than 40 compounds belonging to the above mentioned classes of natural antioxidants. In addition, related reviews published during the same period have been cited. A brief introduction to general bioavailability-related definitions, procedures and considerations is also included. PMID:26784467

  20. [A case of skin autograft for skin ulcers in ichthyosis].

    PubMed

    Li, Shiwei; Yang, Xiaodong; Liu, Lijun; Tang, Xueyang

    2017-10-28

    Ichthyosis refers to a group of skin diseases characterized by abnormal keratinization of the epidermis, resulting in dryness, roughness and scale of the skin. A girl with ichthyosis, who presented with skin ulcers and infection of the right dorsal foot, was admitted to our department. An autologous razor-thin skin grafting procedure was performed to repair the skin ulcers after debridement and vacuum sealing drain. After 8 months of follow-up, both the donor and recipient site healed well and there were no newly formed ulcers or infections. Although the skin quality of ichthyosis is poor, the lesion area can still be used as donor or recipient cite.

  1. Fluorescein and Indocyanine Green Angiography for Uveitis

    PubMed Central

    Herbort, Carl P

    2009-01-01

    In recent years enormous progress has been achieved in investigational procedures for uveitis. Imaging is one such example with the advent of new methods such as indocyanine green angiography, ultrasound biomicroscopy and optical coherence tomography to cite only the most important. This tremendous increase in precision and accuracy in the assessment of the level and degree of inflammation and its monitoring comes in parallel with the development of extremely potent and efficacious therapies. In view of these developments, our whole attitude in the appraisal and investigation of the uveitis patient has to be adapted and correctly reoriented integrating the recent developments and this is no different for ocular angiography. PMID:20404985

  2. RCRA, Superfund and EPCRA hotline training module. Introduction to: Superfund liability, enforcement, and settlements (updated February 1998); Directive

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    1998-06-01

    The goal of this module is to describe the liability, enforcement, and settlement provisions of CERCLA; list the CERCLA enforcement mechanisms available to EPA; explain CERCLA sections 104 and 106 provisions; define potentially responsible party; explain CERCLA section 107 liability; cite and locate the relevant CERCLA documents on enforcement and liability; explain the differences between administrative and judicial enforcement and settlement procedures; list and compare the differences between enforcement authorities as they apply to removal and remedial actions; list the key enforcement steps in EPA`s response process; and specify noncompliance penalties and provide statutory citations.

  3. 22 CFR 96.100 - Procedures for evaluating applicants for temporary accreditation.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...) Procedures and Standards Relating to Temporary Accreditation § 96.100 Procedures for evaluating applicants... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Procedures for evaluating applicants for... entity must: (1) Review the agency's written application and supporting documentation; and (2) Verify the...

  4. Preserving the Integrity of Citations and References by All Stakeholders of Science Communication.

    PubMed

    Gasparyan, Armen Yuri; Yessirkepov, Marlen; Voronov, Alexander A; Gerasimov, Alexey N; Kostyukova, Elena I; Kitas, George D

    2015-11-01

    Citations to scholarly items are building bricks for multidisciplinary science communication. Citation analyses are currently influencing individual career advancement and ranking of academic and research institutions worldwide. This article overviews the involvement of scientific authors, reviewers, editors, publishers, indexers, and learned associations in the citing and referencing to preserve the integrity of science communication. Authors are responsible for thorough bibliographic searches to select relevant references for their articles, comprehend main points, and cite them in an ethical way. Reviewers and editors may perform additional searches and recommend missing essential references. Publishers, in turn, are in a position to instruct their authors over the citations and references, provide tools for validation of references, and open access to bibliographies. Publicly available reference lists bear important information about the novelty and relatedness of the scholarly items with the published literature. Few editorial associations have dealt with the issue of citations and properly managed references. As a prime example, the International Committee of Medical Journal Editors (ICMJE) issued in December 2014 an updated set of recommendations on the need for citing primary literature and avoiding unethical references, which are applicable to the global scientific community. With the exponential growth of literature and related references, it is critically important to define functions of all stakeholders of science communication in curbing the issue of irrational and unethical citations and thereby improve the quality and indexability of scholarly journals.

  5. Preserving the Integrity of Citations and References by All Stakeholders of Science Communication

    PubMed Central

    Yessirkepov, Marlen; Voronov, Alexander A.; Gerasimov, Alexey N.; Kostyukova, Elena I.; Kitas, George D.

    2015-01-01

    Citations to scholarly items are building bricks for multidisciplinary science communication. Citation analyses are currently influencing individual career advancement and ranking of academic and research institutions worldwide. This article overviews the involvement of scientific authors, reviewers, editors, publishers, indexers, and learned associations in the citing and referencing to preserve the integrity of science communication. Authors are responsible for thorough bibliographic searches to select relevant references for their articles, comprehend main points, and cite them in an ethical way. Reviewers and editors may perform additional searches and recommend missing essential references. Publishers, in turn, are in a position to instruct their authors over the citations and references, provide tools for validation of references, and open access to bibliographies. Publicly available reference lists bear important information about the novelty and relatedness of the scholarly items with the published literature. Few editorial associations have dealt with the issue of citations and properly managed references. As a prime example, the International Committee of Medical Journal Editors (ICMJE) issued in December 2014 an updated set of recommendations on the need for citing primary literature and avoiding unethical references, which are applicable to the global scientific community. With the exponential growth of literature and related references, it is critically important to define functions of all stakeholders of science communication in curbing the issue of irrational and unethical citations and thereby improve the quality and indexability of scholarly journals. PMID:26538996

  6. Atmospheric and meteorological Lidar: from pioneers to space applications

    NASA Astrophysics Data System (ADS)

    Flamant, Pierre H.

    2005-10-01

    The 'Light Detection and Ranging' technique, or Lidar, is a laser application to remote sensing. Lidar was in the laboratory stage in the 1960s and in less than 40 years it became a serious candidate for space applications at the turn of the 21st century. Over the years, the Lidar community made significant contributions to Lidar sciences and advancing the technique that makes Lidar an inevitable partner in geophysics and Earth observation. The French community, especially the Service d'Aéronomie and Laboratoire de Météorologie Dynamique, have been involved since the beginning in the Lidar venture and made significant contribution. To cite this article: P.H. Flamant, C. R. Physique 6 (2005).

  7. NASA patent abstracts bibliography: A continuing bibliography. Section 1: Abstracts (supplement 07)

    NASA Technical Reports Server (NTRS)

    1975-01-01

    This bibliography is issued in two sections: Section 1 - Abstracts, and Section 2 - Indexes. This issue of the Abstract Section cites 158 patents and applications for patent introduced into the NASA scientific and technical information system during the period of January 1975 through June 1975. Each entry in the Abstract Section consists of a citation, an abstract, and, in most cases, a key illustration selected from the patent or application for patent. This issue of the Index Section contains entries for 2830 patent and application for patent citations covering the period May 1969 through June 1975. The index section contains five indexes -- subject, inventor, source, number and accession number.

  8. NASA patent abstracts bibliography: A continuing bibliography. Section 1: Abstracts (supplement 09)

    NASA Technical Reports Server (NTRS)

    1976-01-01

    This bibliography is issued in two sections: Section 1 - Abstracts, and Section 2 - Indexes. This issue of the Abstract Section cites 200 patents and applications for patent introduced into the NASA scientific and technical information system during the period of January 1976 through June 1976. Each entry in the Abstract Section consists of a citation, an abstract, and in most cases, a key illustration selected from the patent or application for patent. This issue of the Index Section contains entries for 2994 patent and application for patent citations covering the period May 1969 through June 1976. The Index Section contains five indexes -- subject, inventor, source, number and accession number.

  9. NASA patent abstracts bibliography: A continuing bibliography. Section 2: Indexes (supplement 08)

    NASA Technical Reports Server (NTRS)

    1976-01-01

    This bibliography is issued in two sections: Section 1 - Abstracts, and Section 2 - Indexes. This issue of the Abstract Section cites 180 patents and applications for patents introduced into the NASA scientific and technical information system during the period July 1975 through December 1975. Each entry in the Abstract Section consists of a citation, an abstract, and, in most cases, a key illustration selected from the patent or application for patent. This issue of the Index Section contains entries for 2,905 patents and applications for patent citations covering the period May 1969 through December 1975. The Index Section contains five indexes -- subject, inventor, source, number, and accession number.

  10. Role of CFD in propulsion design - Government perspective

    NASA Technical Reports Server (NTRS)

    Schutzenhofer, L. A.; Mcconnaughey, H. V.; Mcconnaughey, P. K.

    1990-01-01

    Various aspects of computational fluid dynamics (CFD), as it relates to design applications in rocket propulsion activities from the government perspective, are discussed. Specific examples are given that demonstrate the application of CFD to support hardware development activities, such as Space Shuttle Main Engine flight issues, and the associated teaming strategy used for solving such problems. In addition, select examples that delineate the motivation, methods of approach, goals and key milestones for several space flight progams are cited. An approach is described toward applying CFD in the design environment from the government perspective. A discussion of benchmark validation, advanced technology hardware concepts, accomplishments, needs, future applications, and near-term expectations from the flight-center perspective is presented.

  11. Bibliometric analysis of top 100 cited articles in nonalcoholic fatty liver disease research.

    PubMed

    Zhang, Tong-Shuo; Qin, Hua-Lei; Wang, Tong; Li, Hai-Tao; Li, Hai; Xia, Shi-Hai; Xiang, Xiao-Hui

    2016-11-28

    To identify and assess the research situation of top 100 cited articles in nonalcoholic fatty liver disease (NAFLD). The global scientific research articles in the Science Citation Index-Expanded relevant to NAFLD were retrieved and listed according to their citation times from the most to the least. The 100 most frequently cited original articles were selected to systematically evaluate their bibliometric parameters including times cited, publication year, journals, subject categories, and the highly related concepts of NAFLD, which reflected the history and current situation, publication distribution of leading countries and institutes as well as the research hotspots of NAFLD. Top 100 cited articles in NAFLD were published from 1965 to 2015 with a citation ranging of 227 to 2151 times since publication, in which the United States was the most predominant country and Mayo Clin was the most productive institution. The majority of the top 100 cited articles were concentrated in SCI subject category of Gastroenterology and Hepatology. Hepatology and Gastroenterology is the top journal that published over half 100 top-cited articles. The significant peak of top cited articles present in the first half of the 2000s while the highest mean number of citation presents in first half of the 1980s. In addition, concepts related to pathology characteristics, epidemiology and medicalization, metabolic syndrome and its combination of symptoms including insulin resistance, biomarkers of lipid metabolism and obesity are listed as the highly related concepts. The 100 top-cited articles marked with the leading countries, institutions, journals, hotspots and development trend in NAFLD field that could provide the foundation for further investigations.

  12. Physiological loading of joints prevents cartilage degradation through CITED2

    PubMed Central

    Leong, Daniel J.; Li, Yong H.; Gu, Xiang I.; Sun, Li; Zhou, Zuping; Nasser, Philip; Laudier, Damien M.; Iqbal, Jameel; Majeska, Robert J.; Schaffler, Mitchell B.; Goldring, Mary B.; Cardoso, Luis; Zaidi, Mone; Sun, Hui B.

    2011-01-01

    Both overuse and disuse of joints up-regulate matrix metalloproteinases (MMPs) in articular cartilage and cause tissue degradation; however, moderate (physiological) loading maintains cartilage integrity. Here, we test whether CBP/p300-interacting transactivator with ED-rich tail 2 (CITED2), a mechanosensitive transcriptional coregulator, mediates this chondroprotective effect of moderate mechanical loading. In vivo, hind-limb immobilization of Sprague-Dawley rats up-regulates MMP-1 and causes rapid, histologically detectable articular cartilage degradation. One hour of daily passive joint motion prevents these changes and up-regulates articular cartilage CITED2. In vitro, moderate (2.5 MPa, 1 Hz) intermittent hydrostatic pressure (IHP) treatment suppresses basal MMP-1 expression and up-regulates CITED2 in human chondrocytes, whereas high IHP (10 MPa) down-regulates CITED2 and increases MMP-1. Competitive binding and transcription assays demonstrate that CITED2 suppresses MMP-1 expression by competing with MMP transactivator, Ets-1 for its coactivator p300. Furthermore, CITED2 up-regulation in vitro requires the p38δ isoform, which is specifically phosphorylated by moderate IHP. Together, these studies identify a novel regulatory pathway involving CITED2 and p38δ, which may be critical for the maintenance of articular cartilage integrity under normal physical activity levels.—Leong, D. J., Li, Y. H., Gu, X. I., Sun, L., Zhou, Z., Nasser, P., Laudier, D. M., Iqbal, J., Majeska, R. J., Schaffler, M. B., Goldring, M. B., Cardoso, L., Zaidi, M., Sun, H. B. Physiological loading of joints prevents cartilage degradation through CITED2. PMID:20826544

  13. Top-cited articles in digestive system disease from 1950 to 2013.

    PubMed

    Tang, Xiaowei; Gong, Wei; Yuan, Fangfang; Li, Ran; Han, Xiaomei; Huang, Silin; Zhi, Fachao; Jiang, Bo

    2016-01-01

    Examination of top-cited articles is a tool that can help to identify and monitor outstanding scientific researches and landmark papers. We aimed to identify the 100 most cited published papers in peer-reviewed biomedical journals in the field of digestive diseases and to examine their characteristics. The Web of Science (including Science Citation Index) was searched for the most cited papers related to digestive diseases, published from 1955 to the present. The top 100 most cited articles were identified. The number of citations, countries, and institutions of origin, year of publication, study design, topic, and levels of evidence of the articles were noted and analyzed. The most top-cited articles had a mean of 1375 citations. These articles were published between 1978 and 2009 in 29 high-impact journals, with the New England Journal of Medicine (n = 22) topping the list. Of the 100 articles, 34 were clinical studies, 15 were review articles, and 34 were concerned basic science. These articles came from 18 countries, with the USA contributing most of the top-cited articles (n = 53). Eighty-seven institutions produced these 100 top-cited articles, led by the University of Barcelona (n = 4). Seven persons authored two or more of these top-cited articles. The mostly represented specialty was gastrointestinal oncology (n = 49). Our study can give a historical perspective on the scientific progress of digestive diseases, as well as allow for recognition of most important advances in this area and provide useful information to guide future researches. © 2015 Journal of Gastroenterology and Hepatology Foundation and Wiley Publishing Asia Pty Ltd.

  14. Statistical methods for the analysis of climate extremes

    NASA Astrophysics Data System (ADS)

    Naveau, Philippe; Nogaj, Marta; Ammann, Caspar; Yiou, Pascal; Cooley, Daniel; Jomelli, Vincent

    2005-08-01

    Currently there is an increasing research activity in the area of climate extremes because they represent a key manifestation of non-linear systems and an enormous impact on economic and social human activities. Our understanding of the mean behavior of climate and its 'normal' variability has been improving significantly during the last decades. In comparison, climate extreme events have been hard to study and even harder to predict because they are, by definition, rare and obey different statistical laws than averages. In this context, the motivation for this paper is twofold. Firstly, we recall the basic principles of Extreme Value Theory that is used on a regular basis in finance and hydrology, but it still does not have the same success in climate studies. More precisely, the theoretical distributions of maxima and large peaks are recalled. The parameters of such distributions are estimated with the maximum likelihood estimation procedure that offers the flexibility to take into account explanatory variables in our analysis. Secondly, we detail three case-studies to show that this theory can provide a solid statistical foundation, specially when assessing the uncertainty associated with extreme events in a wide range of applications linked to the study of our climate. To cite this article: P. Naveau et al., C. R. Geoscience 337 (2005).

  15. Assessment of a high-resolution central scheme for the solution of the relativistic hydrodynamics equations

    NASA Astrophysics Data System (ADS)

    Lucas-Serrano, A.; Font, J. A.; Ibáñez, J. M.; Martí, J. M.

    2004-12-01

    We assess the suitability of a recent high-resolution central scheme developed by \\cite{kurganov} for the solution of the relativistic hydrodynamic equations. The novelty of this approach relies on the absence of Riemann solvers in the solution procedure. The computations we present are performed in one and two spatial dimensions in Minkowski spacetime. Standard numerical experiments such as shock tubes and the relativistic flat-faced step test are performed. As an astrophysical application the article includes two-dimensional simulations of the propagation of relativistic jets using both Cartesian and cylindrical coordinates. The simulations reported clearly show the capabilities of the numerical scheme of yielding satisfactory results, with an accuracy comparable to that obtained by the so-called high-resolution shock-capturing schemes based upon Riemann solvers (Godunov-type schemes), even well inside the ultrarelativistic regime. Such a central scheme can be straightforwardly applied to hyperbolic systems of conservation laws for which the characteristic structure is not explicitly known, or in cases where a numerical computation of the exact solution of the Riemann problem is prohibitively expensive. Finally, we present comparisons with results obtained using various Godunov-type schemes as well as with those obtained using other high-resolution central schemes which have recently been reported in the literature.

  16. Big data for big questions: it is time for data analysts to act

    PubMed Central

    Moscato, Pablo

    2015-01-01

    Pablo Moscato speaks to Francesca Lake, Managing Editor Australian Research Council Future Fellow Prof. Pablo Moscato was born in 1964 in La Plata, Argentina. Obtaining his B.Sc. in Physics at University of La Plata, his PhD was defended at UNICAMP, Brazil. While at the California Institute of Technology Concurrent Computation Program he developed, in collaboration with Michael Norman, the first application of a methodology later called ‘memetic algorithms’, which is now widely used internationally. He is the founding co-director of the Priority Research Centre for Bioinformatics, Biomarker Discovery and Information-based Medicine (CIBM) (2006–present) and the funding director of the Newcastle Bioinformatics Initiative (2002–2006) of The University of Newcastle (Australia). He is also Chief Investigator of the Australian Research Council Centre in Bioinformatics. He is one of Australia's most cited computer scientists. Over the past 7 years, he has introduced a unifying hallmark of cancer progression based on the changes of information theory quantifiers, and developed a novel mathematical model and an associated solution procedure based on combinatorial optimization techniques to identify drug combinations for cancer therapeutics. In addition, he has identified proteomic signatures to predict the clinical symptoms of Alzheimer's disease, among other ‘firsts’. He is a member of the Editorial Board of Future Science OA. PMID:28031895

  17. 50 CFR 23.17 - What are the requirements for CITES specimens traded internationally by diplomatic, consular...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... ENDANGERED SPECIES OF WILD FAUNA AND FLORA (CITES) Prohibitions, Exemptions, and Requirements § 23.17 What... other persons exempt from customs duties or inspections? A specimen of a CITES species imported...

  18. 50 CFR 23.17 - What are the requirements for CITES specimens traded internationally by diplomatic, consular...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... ENDANGERED SPECIES OF WILD FAUNA AND FLORA (CITES) Prohibitions, Exemptions, and Requirements § 23.17 What... other persons exempt from customs duties or inspections? A specimen of a CITES species imported...

  19. 50 CFR 23.17 - What are the requirements for CITES specimens traded internationally by diplomatic, consular...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... ENDANGERED SPECIES OF WILD FAUNA AND FLORA (CITES) Prohibitions, Exemptions, and Requirements § 23.17 What... other persons exempt from customs duties or inspections? A specimen of a CITES species imported...

  20. Source diversity among journals cited in Science Times.

    PubMed

    Kiernan, Vincent

    2016-02-01

    A content analysis of The New York Times' Science Times section from 1998 to 2012 found evidence of increased source diversity in use of scientific journals as news sources. Science Times increased the frequency at which it cited journals, the number of different journals that it cited, and the number of disciplines represented by cited journals. The results suggest that online availability of a wide array of scientific journals has changed sourcing behaviors. © The Author(s) 2014.

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