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Sample records for clase ii restauradas

  1. El mensaje de conservacion de las instalaciones restauradas del Instituto Internacional de Dasonomia Tropical

    Treesearch

    Ariel Lugo; J. Rullan

    2015-01-01

    Durante un periodo de aproximadamente 20 años, el Instituto Internacional de Dasonomía Tropical y sus colaboradores desarrollaron e implementaron un plan de instalaciones que abarcaba tanto las instalaciones nuevas, como las restauradas. Entre las instalaciones restauradas, el edificio histórico de la sede institucional recibió una Certificación Dorada por Liderazgo en...

  2. Four Cases of a Sociocultural Approach to Mobile Learning in "La Clase Mágica," an Afterschool Technology Club

    ERIC Educational Resources Information Center

    Prieto, Linda; Arreguín-Anderson, María G.; Yuen, Timothy T.; Ek, Lucila D.; Sánchez, Patricia; Machado-Casas, Margarita; García, Adriana

    2016-01-01

    This paper presents four projects in which mobile devices are used to support authentic learning in an afterschool technology club, "La Clase Mágica" (LCM@UTSA), designed to motivate underrepresented elementary school children in science, technology, engineering, and mathematics. The implementation of mobile devices into our LCM@UTSA is…

  3. Actitudes de los candidatos y maestros de ciencias en servicio acerca del uso de las herramientas computadorizadas en las clases de ciencias

    NASA Astrophysics Data System (ADS)

    Bayuelo, Ezequiel

    Este estudio examino y comparo las actitudes de los candidatos a maestros de ciencias y los maestros de ciencias en servicio acerca de la utilizacion de las herramientas computadorizadas en las clases de ciencias. Tambien identifico y diferencio el uso que ellos dan a estas herramientas en las clases de ciencias. Este estudio presenta un diseno descriptivo exploratorio. Constituyeron la muestra trescientos diez sujetos que fueron candidatos a maestros de ciencias o maestros de ciencias en servicio. Para recoger los datos se construyo y valido un cuestionario de treinta y un itemes. Se utilizaron las pruebas estadisticas no parametricas Kruskal Wallis y Chi-cuadrado (test de homogeneidad) para establecer las diferencias entre las actitudes de los sujetos con relacion al uso de las herramientas computadorizadas en las clases de ciencias. Los hallazgos evidenciaron que son positivas y muy parecidas las actitudes de los candidatos a maestros y maestros en servicio hacia el uso de las herramientas computadorizadas. No hubo diferencias entre los candidatos y maestros en servicio en terminos de las actitudes de confianza y empatia hacia el uso de las herramientas computadorizadas en las clases de ciencias. En aspectos como el uso del banco de datos bibliografico Eric y el uso de las herramientas computadorizadas en actividades educativas como explorar conceptos, conceptuar, aplicar lo aprendido y hacer asignaciones hubo diferencias estadisticamente significativas entre los candidatos y los maestros en servicio. Al comparar las frecuencias observadas con las esperadas hubo mas maestros en servicio y menos candidatos que indicaron usar el anterior banco de datos y las herramientas computadorizadas en las mencionadas actividades educativas.

  4. BASS II

    NASA Image and Video Library

    2014-02-14

    ISS038-E-047576 (14 Feb. 2014) --- NASA astronaut Rick Mastracchio, Expedition 38 flight engineer, works with the Burning and Suppression of Solids (BASS-II) experiment in the Microgravity Science Glovebox (MSG) located in the Destiny laboratory of the International Space Station. BASS-II explores how different substances burn in microgravity with benefits for combustion on Earth and fire safety in space.

  5. BASS II

    NASA Image and Video Library

    2014-02-14

    ISS038-E-047582 (14 Feb. 2014) --- NASA astronaut Rick Mastracchio, Expedition 38 flight engineer, works with the Burning and Suppression of Solids (BASS-II) experiment in the Microgravity Science Glovebox (MSG) located in the Destiny laboratory of the International Space Station. BASS-II explores how different substances burn in microgravity with benefits for combustion on Earth and fire safety in space.

  6. Photosystem II

    SciTech Connect

    James Barber

    2005-04-28

    James Barber, Ernst Chain Professor of Biochemistry at Imperial College, London, gives a BSA Distinguished Lecture titled, "The Structure and Function of Photosystem II: The Water-Splitting Enzyme of Photosynthesis."

  7. SAGE II

    Atmospheric Science Data Center

    2016-02-16

    ... of stratospheric aerosols, ozone, nitrogen dioxide, water vapor and cloud occurrence by mapping vertical profiles and calculating ... Updated our estimation of the SAGE II water vapor channel filter location drift resulting in better agreement with more modern datasets ...

  8. Photosystem II

    ScienceCinema

    James Barber

    2017-12-09

    James Barber, Ernst Chain Professor of Biochemistry at Imperial College, London, gives a BSA Distinguished Lecture titled, "The Structure and Function of Photosystem II: The Water-Splitting Enzyme of Photosynthesis."

  9. FAQs II

    ERIC Educational Resources Information Center

    Kezar, Adrianna; Frank, Vikki; Lester, Jaime; Yang, Hannah

    2008-01-01

    In their paper entitled "Why should postsecondary institutions consider partnering to offer (Individual Development Accounts (IDAs)?" the authors reviewed frequently asked questions they encountered from higher education professionals about IDAs, but as their research continued so did the questions. FAQ II has more in-depth questions and…

  10. Welding II.

    ERIC Educational Resources Information Center

    Allegheny County Community Coll., Pittsburgh, PA.

    Instructional objectives and performance requirements are outlined in this course guide for Welding II, a performance-based course offered at the Community College of Allegheny County to introduce students to out-of-position shielded arc welding with emphasis on proper heats, electrode selection, and alternating/direct currents. After introductory…

  11. PORT II

    NASA Technical Reports Server (NTRS)

    Muniz, Beau

    2009-01-01

    One unique project that the Prototype lab worked on was PORT I (Post-landing Orion Recovery Test). PORT is designed to test and develop the system and components needed to recover the Orion capsule once it splashes down in the ocean. PORT II is designated as a follow up to PORT I that will utilize a mock up pressure vessel that is spatially compar able to the final Orion capsule.

  12. BORE II

    SciTech Connect

    2015-08-01

    Bore II, co-developed by Berkeley Lab researchers Frank Hale, Chin-Fu Tsang, and Christine Doughty, provides vital information for solving water quality and supply problems and for improving remediation of contaminated sites. Termed "hydrophysical logging," this technology is based on the concept of measuring repeated depth profiles of fluid electric conductivity in a borehole that is pumping. As fluid enters the wellbore, its distinct electric conductivity causes peaks in the conductivity log that grow and migrate upward with time. Analysis of the evolution of the peaks enables characterization of groundwater flow distribution more quickly, more cost effectively, and with higher resolutionmore » than ever before. Combining the unique interpretation software Bore II with advanced downhole instrumentation (the hydrophysical logging tool), the method quantifies inflow and outflow locations, their associated flow rates, and the basic water quality parameters of the associated formation waters (e.g., pH, oxidation-reduction potential, temperature). In addition, when applied in conjunction with downhole fluid sampling, Bore II makes possible a complete assessment of contaminant concentration within groundwater.« less

  13. APOLLO II

    SciTech Connect

    Sanchez, R.; Mondot, J.; Stankovski, Z.

    1988-11-01

    APOLLO II is a new, multigroup transport code under development at the Commissariat a l'Energie Atomique. The code has a modular structure and uses sophisticated software for data structuralization, dynamic memory management, data storage, and user macrolanguage. This paper gives an overview of the main methods used in the code for (a) multidimensional collision probability calculations, (b) leakage calculations, and (c) homogenization procedures. Numerical examples are given to demonstrate the potential of the modular structure of the code and the novel multilevel flat-flux representation used in the calculation of the collision probabilities.

  14. Investigaccion-accion en la sala de clases sobre las creencias de la cultura de la ciencia de un grupo de estudiantes universitarios y su relacion reciproca con el aprendizaje de las ciencias biologicas

    NASA Astrophysics Data System (ADS)

    Cordova-Santiago, Lizzette Astrid

    La investigacion---accion que se llevo a cabo en la sala de clases tenia como punto de partida las creencias de la cultura de la ciencia de un grupo de estudiantes universitarios para luego examinar sus implicaciones en el proceso de aprendizaje de las Ciencias Biologicas. ¿Que se supone que hagan las creencias en relacion con el aprendizaje? ¿En que consiste incorporar este aspecto a la practica educativa universitaria? Utilizando el modelo de Kemmis y McTaggart (1987) la investigacion-accion se planteo como un proceso dinamico en cuatro momentos en espiral constituidos por la planificacion, la accion, la observacion y la reflexion. Cada una de las fases tuvo una intencion retrospectiva y prospectiva formando una espiral de autorreflexion del conocimiento y la accion. Se llevaron a cabo audio grabaciones en clases y analisis de documentos. Ademas, la profesora-investigadora hizo un portafolio para reflexionar sobre las creencias de la cultura de la ciencia que tienen los estudiantes y las creencias del aprendizaje que tiene la profesora y sobre como la comprension de estos elementos ayudo a mejorar su practica educativa a traves del tiempo. Los resultados obtenidos apuntan a que las creencias de la cultura de la ciencia que tiene el grupo de estudiantes son diversas. Ellos si creen que la ciencia tiene una cultura la cual describieron como: complicada y desconocida que evoluciona constantemente, que es un conjunto de metodos, que es altamente tecnologica, que resuelve problemas de salud, ayuda a interpretar la realidad del mundo que los rodea y su origen y que existen unas intersecciones entre la ciencia y el poder. Sobre las creencias del proceso de aprendizaje de la profesora-investigadora, estas senalan que el modelaje de actores, la vision de la academia que tiene ella asi como la participacion y negociacion entre todos los involucrados en el proceso educativo, son factores que inciden en el proceso de aprendizaje.

  15. Small Diameter Bomb Increment II (SDB II)

    DTIC Science & Technology

    2015-12-01

    Selected Acquisition Report ( SAR ) RCS: DD-A&T(Q&A)823-439 Small Diameter Bomb Increment II (SDB II) As of FY 2017 President’s Budget Defense...Acquisition Management Information Retrieval (DAMIR) March 23, 2016 16:19:13 UNCLASSIFIED SDB II December 2015 SAR March 23, 2016 16:19:13 UNCLASSIFIED...Document OSD - Office of the Secretary of Defense O&S - Operating and Support PAUC - Program Acquisition Unit Cost SDB II December 2015 SAR March 23

  16. Ovarian Cancer Stage II

    MedlinePlus

    ... g. -historical Searches are case-insensitive Ovarian Cancer Stage II Add to My Pictures View /Download : Small: ... Download Large: 3300x1350 View Download Title: Ovarian Cancer Stage II Description: Three-panel drawing of stage IIA, ...

  17. Astronomy in the Classroom: Why? (Spanish Title: Astronomía en la Clase: ¿Por Qué?) Astronomia na Sala de Aula: Por Quê?

    NASA Astrophysics Data System (ADS)

    Daros Gama, Leandro; Bagdonas Henrique, Alexandre

    2010-07-01

    There are many discussions about the relevance of the topics covered in classes. One subject in particular is the focus of this essay: astronomy. In what sense and to what extent it would be worth to teach it in science or other kind of classes? In this paper we discuss some aspects of the advantages of dealing with this area of knowledge in schools, taking into account the epistemological and axiological dimensions of astronomy, in light of the vision of science as an intelligent dialogue with the world (Bachelard), in addition to the "problematization" knowledge of Paulo Freire. We propose that in fact the Astronomy does not need to be seen as just a new set of contents to be taught, but appears as a set of motivational contents for historical-philosophical discussions, and permit the discussion of concepts of other disciplines. Numerosas discusiones se están llevando a cabo acerca de la pertinencia de los temas tradicionalmente tratados en las clases. Uno de los temas, en particular, es el foco de este ensayo: la astronomía. ¿En qué sentido y en qué medida sería conveniente tratarla en clase, ya sea en clases de ciencias naturales, específicamente en las de astronomía o asignaturas afines? Elaboramos en este artículo algunos aspectos de las ventajas de tratar esta área del conocimiento en las escuelas, teniendo en cuenta las dimensiones epistemológica y axiológica de la astronomía, a la luz de la visión de la ciencia como un diálogo inteligente con el mundo (Bachelard), además de la propuesta del conocimiento "problematizador" de Paulo Freire. Proponemos que en realidad la astronomía no tiene por qué ser vista sólo como un nuevo conjunto de contenidos que se enseñan, sino que aparece como un conjunto de temas de motivación para el debate histórico-filosófico y para permitir la discusión de los conceptos típicos de otras disciplinas. Muitas discussões vêm acontecendo sobre a relevância dos temas abordados em sala de aula. Um tema, em

  18. BASS-II Experiment

    NASA Image and Video Library

    2014-08-02

    Image taken on card 8 during BASS-II flame test session with reduced O2 partial pressure. Session conducted on GMT 213. The Burning and Suppression of Solids - II (BASS-II) investigation examines the burning and extinction characteristics of a wide variety of fuel samples in microgravity. The BASS-II experiment will guide strategies for materials flammability screening for use in spacecraft as well as provide valuable data on solid fuel burning behavior in microgravity. BASS-II results contribute to the combustion computational models used in the design of fire detection and suppression systems in microgravity and on Earth.

  19. World War II Homefront.

    ERIC Educational Resources Information Center

    Garcia, Rachel

    2002-01-01

    Presents an annotated bibliography that provides Web sites focusing on the U.S. homefront during World War II. Covers various topics such as the homefront, Japanese Americans, women during World War II, posters, and African Americans. Includes lesson plan sources and a list of additional resources. (CMK)

  20. Mobile group II introns.

    PubMed

    Lambowitz, Alan M; Zimmerly, Steven

    2004-01-01

    Mobile group II introns, found in bacterial and organellar genomes, are both catalytic RNAs and retrotransposable elements. They use an extraordinary mobility mechanism in which the excised intron RNA reverse splices directly into a DNA target site and is then reverse transcribed by the intron-encoded protein. After DNA insertion, the introns remove themselves by protein-assisted, autocatalytic RNA splicing, thereby minimizing host damage. Here we discuss the experimental basis for our current understanding of group II intron mobility mechanisms, beginning with genetic observations in yeast mitochondria, and culminating with a detailed understanding of molecular mechanisms shared by organellar and bacterial group II introns. We also discuss recently discovered links between group II intron mobility and DNA replication, new insights into group II intron evolution arising from bacterial genome sequencing, and the evolutionary relationship between group II introns and both eukaryotic spliceosomal introns and non-LTR-retrotransposons. Finally, we describe the development of mobile group II introns into gene-targeting vectors, "targetrons," which have programmable target specificity.

  1. MEDLARS II: A Review *

    PubMed Central

    Sodergren, Linnea

    1973-01-01

    The MEDLARS II effort, as it was developed until June 1971, is reviewed in terms of the overall planning process. How MEDLARS I was approached by NLM is discussed first and its objectives used for comparison. Certain technical, managerial, and intellectual aspects are outlined as types of problems encountered in designing MEDLARS II. While improvement upon the MEDLARS I seemed to be the main reason for planning a MEDLARS II, objectives became blurred and divergent as the project went along. The complexities of creating a central computerized data base of health sciences bibliographic information and library functional activities for nationwide use were underappreciated and remain a challenge to NLM. PMID:4582930

  2. Multiple endocrine neoplasia (MEN) II

    MedlinePlus

    Sipple syndrome; MEN II; Pheochromocytoma - MEN II; Thyroid cancer - pheochromocytoma; Parathyroid cancer - pheochromocytoma ... The cause of MEN II is a defect in a gene called RET. This defect causes many tumors to appear in the same ...

  3. Mucopolysaccharidosis type II

    MedlinePlus

    Genetic counseling is recommended for couples who want to have children and who have a family history of MPS II. Prenatal testing is available. Carrier testing for female relatives of affected males is available at a few centers.

  4. Carnitine palmitoyltransferase II deficiency

    PubMed Central

    Roe, C R.; Yang, B-Z; Brunengraber, H; Roe, D S.; Wallace, M; Garritson, B K.

    2008-01-01

    Background: Carnitine palmitoyltransferase II (CPT II) deficiency is an important cause of recurrent rhabdomyolysis in children and adults. Current treatment includes dietary fat restriction, with increased carbohydrate intake and exercise restriction to avoid muscle pain and rhabdomyolysis. Methods: CPT II enzyme assay, DNA mutation analysis, quantitative analysis of acylcarnitines in blood and cultured fibroblasts, urinary organic acids, the standardized 36-item Short-Form Health Status survey (SF-36) version 2, and bioelectric impedance for body fat composition. Diet treatment with triheptanoin at 30% to 35% of total daily caloric intake was used for all patients. Results: Seven patients with CPT II deficiency were studied from 7 to 61 months on the triheptanoin (anaplerotic) diet. Five had previous episodes of rhabdomyolysis requiring hospitalizations and muscle pain on exertion prior to the diet (two younger patients had not had rhabdomyolysis). While on the diet, only two patients experienced mild muscle pain with exercise. During short periods of noncompliance, two patients experienced rhabdomyolysis with exercise. None experienced rhabdomyolysis or hospitalizations while on the diet. All patients returned to normal physical activities including strenuous sports. Exercise restriction was eliminated. Previously abnormal SF-36 physical composite scores returned to normal levels that persisted for the duration of the therapy in all five symptomatic patients. Conclusions: The triheptanoin diet seems to be an effective therapy for adult-onset carnitine palmitoyltransferase II deficiency. GLOSSARY ALT = alanine aminotransferase; AST = aspartate aminotransferase; ATP = adenosine triphosphate; BHP = β-hydroxypentanoate; BKP = β-ketopentanoate; BKP-CoA = β-ketopentanoyl–coenzyme A; BUN = blood urea nitrogen; CAC = citric acid cycle; CoA = coenzyme A; CPK = creatine phosphokinase; CPT II = carnitine palmitoyltransferase II; LDL = low-density lipoprotein; MCT

  5. Topoisomerase II and leukemia

    PubMed Central

    Pendleton, MaryJean; Lindsey, R. Hunter; Felix, Carolyn A.; Grimwade, David; Osheroff, Neil

    2014-01-01

    Type II topoisomerases are essential enzymes that modulate DNA under- and overwinding, knotting, and tangling. Beyond their critical physiological functions, these enzymes are the targets for some of the most widely prescribed anticancer drugs (topoisomerase II poisons) in clinical use. Topoisomerase II poisons kill cells by increasing levels of covalent enzyme-cleaved DNA complexes that are normal reaction intermediates. Drugs such as etoposide, doxorubicin, and mitoxantrone are frontline therapies for a variety of solid tumors and hematological malignancies. Unfortunately, their use is also associated with the development of specific leukemias. Regimens that include etoposide or doxorubicin are linked to the occurrence of acute myeloid leukemias that feature rearrangements at chromosomal band 11q23. Similar rearrangements are seen in infant leukemias and are associated with gestational diets that are high in naturally occurring topoisomerase II–active compounds. Finally, regimens that include mitoxantrone and epirubicin are linked to acute promyelocytic leukemias that feature t(15;17) rearrangements. The first part of this article will focus on type II topoisomerases and describe the mechanism of enzyme and drug action. The second part will discuss how topoisomerase II poisons trigger chromosomal breaks that lead to leukemia and potential approaches for dissociating the actions of drugs from their leukemogenic potential. PMID:24495080

  6. About APPLE II Operation

    SciTech Connect

    Schmidt, T.; Zimoch, D.

    2007-01-19

    The operation of an APPLE II based undulator beamline with all its polarization states (linear horizontal and vertical, circular and elliptical, and continous variation of the linear vector) requires an effective description allowing an automated calculation of gap and shift parameter as function of energy and operation mode. The extension of the linear polarization range from 0 to 180 deg. requires 4 shiftable magnet arrrays, permitting use of the APU (adjustable phase undulator) concept. Studies for a pure fixed gap APPLE II for the SLS revealed surprising symmetries between circular and linear polarization modes allowing for simplified operation. A semi-analyticalmore » model covering all types of APPLE II and its implementation will be presented.« less

  7. SAGE II Ozone Analysis

    NASA Technical Reports Server (NTRS)

    Cunnold, Derek; Wang, Ray

    2002-01-01

    Publications from 1999-2002 describing research funded by the SAGE II contract to Dr. Cunnold and Dr. Wang are listed below. Our most recent accomplishments include a detailed analysis of the quality of SAGE II, v6.1, ozone measurements below 20 km altitude (Wang et al., 2002 and Kar et al., 2002) and an analysis of the consistency between SAGE upper stratospheric ozone trends and model predictions with emphasis on hemispheric asymmetry (Li et al., 2001). Abstracts of the 11 papers are attached.

  8. Periodontics II: Course Proposal.

    ERIC Educational Resources Information Center

    Dordick, Bruce

    A proposal is presented for Periodontics II, a course offered at the Community College of Philadelphia to give the dental hygiene/assisting student an understanding of the disease states of the periodontium and their treatment. A standardized course proposal cover form is given, followed by a statement of purpose for the course, a list of major…

  9. CULTIVATION OF LEPTOSPIRAE II.

    PubMed Central

    Stalheim, O. H. V.; Wilson, J. B.

    1964-01-01

    Stalheim, O. H. V. (University of Wisconsin, Madison), and J. B. Wilson. Cultivation of leptospirae. II. Growth and lysis in synthetic medium. J. Bacteriol. 88:55–59. 1964.—Differences were found in the ability of leptospirae to grow in a synthetic medium; 43 strains, consisting of 16 serotypes, were tested and designated as either type I or type II. Type I leptospirae did not grow; type II grew and could be subcultured. The lytic effect of several lipids was measured with Leptospira pomona and L. canicola as representatives of type I and II leptospirae, respectively. L. pomona organisms were rapidly lysed by the monoolein of the synthetic medium and by other lipids as well; L. canicola cells were consistently more resistant. Although both organisms incorporated similar amounts of label when incubated in the presence of oleic-1-C14 acid, only L. canicola grew in a modified, nonlytic synthetic medium. No differences were found in susceptibility to lysis between virulent and avirulent L. canicola organisms. Mutant type I leptospirae grown in synthetic medium had increased resistance to lysis by surface-active agents; they were poorly agglutinated by antiserum. The role of protein in the growth and antigenicity of type I leptospirae is discussed. PMID:14197906

  10. Instant Insanity II

    ERIC Educational Resources Information Center

    Richmond, Tom; Young, Aaron

    2013-01-01

    "Instant Insanity II" is a sliding mechanical puzzle whose solution requires the special alignment of 16 colored tiles. We count the number of solutions of the puzzle's classic challenge and show that the more difficult ultimate challenge has, up to row permutation, exactly two solutions, and further show that no…

  11. Computing at Belle II

    NASA Astrophysics Data System (ADS)

    Pardi, Silvio; de Nardo, Guglielmo; Russo, Guido; Belle II computing Group

    2016-04-01

    The existence of large matter-antimatter asymmetry (CP violation) in the b-quark system as predicted in the Kobayashi-Maskawa theory was established by the B-Factory experiments, Belle and BaBar. However, this cannot explain the magnitude of the matter-antimatter asymmetry of the universe we live in today. This indicates undiscovered new physics exists. The Belle II experiment, the next generation of the B-Factory, is expected to reveal the new physics by accumulating 50 times more data (˜ 50ab-1) than Belle by 2023. The Belle II computing system has to handle an amount of beam data eventually corresponding to several tens of PetaByte per year under an operation of the SuperKEKB accelerator with a designed instantaneous luminosity. Under this situation, it cannot be expected that one site, KEK, will be able to provide all computing resources for the whole Belle II collaboration including the resources not only for the raw data processing but also for the MC production and physics analysis done by users. In order to solve this problem, Belle II employed the distributed computing system based on DIRAC, which provides us the interoperability of heterogeneous computing systems such as grids with different middleware, clouds and the local computing clusters. Since the last year, we performed the MC mass production campaigns to confirm the feasibility and find out the possible bottleneck of our computing system. In parallel, we also started the data transfer challenge through the transpacific and transatlantic networks. This presentation describes the highlights of the Belle II computing and the current status. We will also present the experience of the latest MC production campaign in 2014.

  12. European Telecommunications Satellite II (EUTELSAT II)

    NASA Technical Reports Server (NTRS)

    Laemmel, G.; Brittinger, P.

    1991-01-01

    EUTELSAT II is a regional public telecommunications system for Europe. The services which will be provided are telephone and television. The satellites will be placed at a geostationary orbit within the arcs of 6 degrees east to 19 degrees east or 26 degrees to 36 degrees east. The designed lifetime is 7 years. After separation of the satellites from the launch vehicles, telemetry, telecommand, and ranging will be performed within the S-band frequencies. After positioning of the satellite at its final geostationary orbit, the Ku-band telecommunication equipment will be activated. From this time on, all satellite control operations will be performed in Ku-band. The Deep Space Network (DSN) will support the transfer and drift orbit mission phases. The coverage will consist of the 26-m antennas at Goldstone and Canberra as prime support for the transfer and drift orbits. Maximum support will consist of a 7-day period, plus 14 days of contingency support. Information is given in tabular form for DSN support, frequency assignments, telemetry, command, and tracking support responsibility.

  13. Angiotensin II regulates oxygen consumption.

    PubMed

    Cassis, Lisa; Helton, Marc; English, Vicki; Burke, Gerome

    2002-02-01

    Previous studies demonstrated that angiotensin II (ANG II) decreases body weight. This study examined whether ANG II regulates body weight through energy expenditure. Acute ANG II administration decreased oxygen consumption. To determine whether this effect was maintained, rats were infused with ANG II or saline for 14 days. Oxygen consumption was transiently decreased on day 1 of ANG II infusion; however, body weight and food intake were reduced for 14 days. In pair-feeding studies, reductions in food intake accounted for 63% of the effect of ANG II on body weight but did not influence systolic pressure, water intake, or oxygen consumption. With 28 days of ANG II infusion, differences in body weight between ANG II and control rats were of greater magnitude. An initial decrease in oxygen consumption was followed by a rebound increase. Coadministration of losartan prevented the effect of ANG II on body weight, food intake, blood pressure, and water intake. However, losartan only partially prevented ANG II reductions in oxygen consumption. These results demonstrate that ANG II transiently decreases oxygen consumption through mechanisms unrelated to food intake. With chronic ANG II exposure, energy expenditure may contribute to sustained reductions in body weight.

  14. Where is Population II?

    NASA Astrophysics Data System (ADS)

    Mould, J.; Bianchini, F.; Forbes, Duncan A.; Reichardt, C. L.

    2018-03-01

    The use of roman numerals for stellar populations represents a classification approach to galaxy formation which is now well behind us. Nevertheless, the concept of a pristine generation of stars, followed by a protogalactic era, and finally the mainstream stellar population is a plausible starting point for testing our physical understanding of early star formation. This will be observationally driven as never before in the coming decade. In this paper, we search out observational tests of an idealised coeval and homogeneous distribution of population II stars. We examine the spatial distribution of quasars, globular clusters, and the integrated free electron density of the intergalactic medium, in order to test the assumption of homogeneity. Any real inhomogeneity implies a population II that is not coeval.

  15. Average [O II] nebular emission associated with Mg II absorbers: dependence on Fe II absorption

    NASA Astrophysics Data System (ADS)

    Joshi, Ravi; Srianand, Raghunathan; Petitjean, Patrick; Noterdaeme, Pasquier

    2018-05-01

    We investigate the effect of Fe II equivalent width (W2600) and fibre size on the average luminosity of [O II] λλ3727, 3729 nebular emission associated with Mg II absorbers (at 0.55 ≤ z ≤ 1.3) in the composite spectra of quasars obtained with 3 and 2 arcsec fibres in the Sloan Digital Sky Survey. We confirm the presence of strong correlations between [O II] luminosity (L_{[O II]}) and equivalent width (W2796) and redshift of Mg II absorbers. However, we show L_{[O II]} and average luminosity surface density suffer from fibre size effects. More importantly, for a given fibre size, the average L_{[O II]} strongly depends on the equivalent width of Fe II absorption lines and found to be higher for Mg II absorbers with R ≡W2600/W2796 ≥ 0.5. In fact, we show the observed strong correlations of L_{[O II]} with W2796 and z of Mg II absorbers are mainly driven by such systems. Direct [O II] detections also confirm the link between L_{[O II]} and R. Therefore, one has to pay attention to the fibre losses and dependence of redshift evolution of Mg II absorbers on W2600 before using them as a luminosity unbiased probe of global star formation rate density. We show that the [O II] nebular emission detected in the stacked spectrum is not dominated by few direct detections (i.e. detections ≥3σ significant level). On an average, the systems with R ≥ 0.5 and W2796 ≥ 2 Å are more reddened, showing colour excess E(B - V) ˜ 0.02, with respect to the systems with R < 0.5 and most likely trace the high H I column density systems.

  16. Delta II Mars Pathfinder

    NASA Technical Reports Server (NTRS)

    1998-01-01

    Final preparations for lift off of the DELTA II Mars Pathfinder Rocket are shown. Activities include loading the liquid oxygen, completing the construction of the Rover, and placing the Rover into the Lander. After the countdown, important visual events include the launch of the Delta Rocket, burnout and separation of the three Solid Rocket Boosters, and the main engine cutoff. The cutoff of the main engine marks the beginning of the second stage engine. After the completion of the second stage, the third stage engine ignites and then cuts off. Once the third stage engine cuts off spacecraft separation occurs.

  17. SAGE II aerosol data validation - Comparative studies of SAGE II and SAM II data sets

    NASA Technical Reports Server (NTRS)

    Yue, G. K.; Mccormick, M. P.; Chu, W. P.; Wang, P. H.; Osborn, M. T.

    1989-01-01

    Data from the Stratospheric Aerosol and Gas Experiment (SAGE II) satellite are compared with data from the Stratospheric Aerosol Measurement (SAM II) satellite. Both experiments produce aerosol extinction profiles by measuring the attenuation of solar radiation during each sunrise and sunset observed by the satelltie. The SAGE II obtains profiles at 1.02 microns and three smaller wavelengths, whereas the SAM II measures at only one radiometric channel at 1.0 microns. It is found that the differences between the two sets of data are generally within the error bars associated with each measurement. In addition, the sunrise and sunset data from SAGE II are analyzed.

  18. Class II enveloped viruses.

    PubMed

    Vaney, Marie-Christine; Rey, Felix A

    2011-10-01

    A number of viruses transport their genomic material from cell to cell enclosed within a lipid bilayer that is in turn encased within a symmetric protein shell. This review focuses in a group of RNA viruses that have this type of virions. This group includes several of important human pathogenic viruses, such as the hepatitis C virus, dengue virus, chikungunya virus, rubella virus and the bunyaviruses. The best studied are the flaviviruses and the alphaviruses, which have a β-sheet rich class II viral fusion protein used for entry into susceptible cells. We extend here the class II concept to encompass symmetric viruses in which the envelope proteins are derived from a precursor polyprotein containing two transmembrane glycoproteins arranged in tandem. The first glycoprotein acts as chaperone for the folding of the second one, which carries the membrane fusion function. Since the bunyaviruses, included here, are very similar to the class I arenaviruses in other respects, this analysis highlights the patchwork nature of the various viral functional modules acting at different stages of the virus cycle, which appear assembled from genes of different origins. © 2011 Blackwell Publishing Ltd.

  19. Zn(ii), Cd(ii) and Pb(ii) complexation with pyridinecarboxylate containing ligands.

    PubMed

    Ferreirós-Martínez, Raquel; Esteban-Gómez, David; Platas-Iglesias, Carlos; de Blas, Andrés; Rodríguez-Blas, Teresa

    2008-11-14

    Herein, we report the coordination properties towards Zn(ii), Cd(ii) and Pb(ii) of two hexadentate ligands containing pyridinecarboxylate groups with ethane-1,2-diamine (bcpe) or cyclohexane-1,2-diamine (bcpc) backbones. The X-ray crystal structures of [Zn(bcpe)], [Cd(bcpe)] and [Cd(bcpc)] show hexadentate binding of the ligand to the metal ions, with the coordination polyhedron being best described as a severely distorted octahedron. The X-ray crystal structure of the Pb(ii) analogue shows the presence of tetrameric structural units [Pb(4)(bcpe)(4)] in which the four Pb(ii) ions are bridged by carboxylate oxygen atoms. While in the Zn(ii) and Cd(ii) complexes the bcpe ligand adopts a twist-wrap (tw) conformation in which the ligand wraps around the metal ion by twisting the pyridyl units relative to each other, for the Pb(ii) complex a twist-fold (tf) conformation, where a slight twisting of the pyridyl units is accompanied by an overall folding of the two pyridine units relative to each other is observed. Theoretical calculations performed at the DFT (B3LYP) level on the [Pb(bcpe)] and [Pb(bcpc)] systems indicate that the tf conformation is more stable than the tw form both in the solid state and in aqueous solution. The analysis of the natural bond orbitals (NBOs) indicate that the Pb(ii) lone-pair is polarized by a substantial 6p contribution, which results in a hemi-directed coordination geometry around the metal ion. Potentiometric studies have been carried out to determine the protonation constants of the ligands and the stability constants of the complexes with Zn(ii), Cd(ii), Pb(ii) and Ca(ii). The replacement of the ethylene backbone of bcpe by a cyclohexylene ring causes a very important increase in the stability constant of the Pb(ii) complex (ca. 2.3 logK units), while this effect is less important for Cd(ii) (ca. 1.4 logK units). However, the introduction of the cyclohexylene ring does not substantially affect the stability of the Zn(ii) and Ca(ii

  20. Rosacea: II. Therapy.

    PubMed

    Pelle, Michelle T; Crawford, Glen H; James, William D

    2004-10-01

    Despite an incomplete understanding of the pathogenesis of rosacea, therapeutic modalities continue to expand. The principal subtypes of rosacea include erythematotelangiectatic rosacea, papulopustular rosacea, phymatous rosacea, and ocular rosacea. These phenotypic expressions are probably caused by divergent pathogenic factors and consequently respond to different therapeutic regimens. A subtype-directed approach to therapy is discussed in part II of this review. We provide an overview of the available topical, oral, laser, and light therapies in the context of these cutaneous subtypes, review the evidence that supports their use, and outline their therapeutic approach. Suggestions for future areas of study also are provided. Learning objective At the completion of this learning activity, participants should be familiar with the subtype-directed approach to therapy for rosacea including available topical, oral, laser, and light therapies.

  1. Effect of Cu(II), Cd(II) and Zn(II) on Pb(II) biosorption by algae Gelidium-derived materials.

    PubMed

    Vilar, Vítor J P; Botelho, Cidália M S; Boaventura, Rui A R

    2008-06-15

    Biosorption of Pb(II), Cu(II), Cd(II) and Zn(II) from binary metal solutions onto the algae Gelidium sesquipedale, an algal industrial waste and a waste-based composite material was investigated at pH 5.3, in a batch system. Binary Pb(II)/Cu(II), Pb(II)/Cd(II) and Pb(II)/Zn(II) solutions have been tested. For the same equilibrium concentrations of both metal ions (1 mmol l(-1)), approximately 66, 85 and 86% of the total uptake capacity of the biosorbents is taken by lead ions in the systems Pb(II)/Cu(II), Pb(II)/Cd(II) and Pb(II)/Zn(II), respectively. Two-metal results were fitted to a discrete and a continuous model, showing the inhibition of the primary metal biosorption by the co-cation. The model parameters suggest that Cd(II) and Zn(II) have the same decreasing effect on the Pb(II) uptake capacity. The uptake of Pb(II) was highly sensitive to the presence of Cu(II). From the discrete model it was possible to obtain the Langmuir affinity constant for Pb(II) biosorption. The presence of the co-cations decreases the apparent affinity of Pb(II). The experimental results were successfully fitted by the continuous model, at different pH values, for each biosorbent. The following sequence for the equilibrium affinity constants was found: Pb>Cu>Cd approximately Zn.

  2. Solar Type II Radio Bursts and IP Type II Events

    NASA Technical Reports Server (NTRS)

    Cane, H. V.; Erickson, W. C.

    2005-01-01

    We have examined radio data from the WAVES experiment on the Wind spacecraft in conjunction with ground-based data in order to investigate the relationship between the shocks responsible for metric type II radio bursts and the shocks in front of coronal mass ejections (CMEs). The bow shocks of fast, large CMEs are strong interplanetary (IP) shocks, and the associated radio emissions often consist of single broad bands starting below approx. 4 MHz; such emissions were previously called IP type II events. In contrast, metric type II bursts are usually narrowbanded and display two harmonically related bands. In addition to displaying complete dynamic spectra for a number of events, we also analyze the 135 WAVES 1 - 14 MHz slow-drift time periods in 2001-2003. We find that most of the periods contain multiple phenomena, which we divide into three groups: metric type II extensions, IP type II events, and blobs and bands. About half of the WAVES listings include probable extensions of metric type II radio bursts, but in more than half of these events, there were also other slow-drift features. In the 3 yr study period, there were 31 IP type II events; these were associated with the very fastest CMEs. The most common form of activity in the WAVES events, blobs and bands in the frequency range between 1 and 8 MHz, fall below an envelope consistent with the early signatures of an IP type II event. However, most of this activity lasts only a few tens of minutes, whereas IP type II events last for many hours. In this study we find many examples in the radio data of two shock-like phenomena with different characteristics that occur simultaneously in the metric and decametric/hectometric bands, and no clear example of a metric type II burst that extends continuously down in frequency to become an IP type II event. The simplest interpretation is that metric type II bursts, unlike IP type II events, are not caused by shocks driven in front of CMEs.

  3. Technology II: Implementation Planning Guide.

    ERIC Educational Resources Information Center

    California Community Colleges, Sacramento. Office of the Chancellor.

    The California Community Colleges (CCC) are facing a number of challenges, including the explosive use of the Internet, the digital divide, the need for integrating technology into teaching and learning, the impact of Tidal Wave II, and the need to ensure that technology is accessible to persons with disabilities. The CCCs' Technology II Strategic…

  4. Hopkins during BASS II Setup

    NASA Image and Video Library

    2014-02-12

    ISS038-E-046394 (12 Feb. 2014) --- NASA astronaut Mike Hopkins, Expedition 38 flight engineer, sets up the Microgravity Science Glovebox (MSG) for the Burning and Suppression of Solids (BASS-II) experiment in the Destiny laboratory of the International Space Station. BASS-II explores how different substances burn in microgravity with benefits for combustion on Earth and fire safety in space.

  5. Mastracchio during BASS II Setup

    NASA Image and Video Library

    2014-02-12

    ISS038-E-046391 (12 Feb. 2014) --- NASA astronaut Rick Mastracchio, Expedition 38 flight engineer, sets up the Microgravity Science Glovebox (MSG) for the Burning and Suppression of Solids (BASS-II) experiment in the Destiny laboratory of the International Space Station. BASS-II explores how different substances burn in microgravity with benefits for combustion on Earth and fire safety in space.

  6. Mastracchio during BASS II Setup

    NASA Image and Video Library

    2014-02-12

    ISS038-E-046387 (12 Feb. 2014) --- NASA astronaut Rick Mastracchio, Expedition 38 flight engineer, sets up the Microgravity Science Glovebox (MSG) for the Burning and Suppression of Solids (BASS-II) experiment in the Destiny laboratory of the International Space Station. BASS-II explores how different substances burn in microgravity with benefits for combustion on Earth and fire safety in space.

  7. ACRIM II Data and Information

    Atmospheric Science Data Center

    2017-08-23

    ACRIM II Data and Information Active Cavity Radiometer Irradiance ... NATIVE Tools:  Earthdata Search: Order Data HTML Order Tool:   Order Data Parameters:  ... ACRIM II Instrument Page ACRIM III Data Sets Readme Files:  Readme File Image ...

  8. Hopkins during BASS II Setup

    NASA Image and Video Library

    2014-02-12

    ISS038-E-046393 (12 Feb. 2014) --- NASA astronaut Mike Hopkins, Expedition 38 flight engineer, sets up the Microgravity Science Glovebox (MSG) for the Burning and Suppression of Solids (BASS-II) experiment in the Destiny laboratory of the International Space Station. BASS-II explores how different substances burn in microgravity with benefits for combustion on Earth and fire safety in space.

  9. Mastracchio during BASS II Setup

    NASA Image and Video Library

    2014-02-12

    ISS038-E-046381 (12 Feb. 2014) --- NASA astronaut Rick Mastracchio, Expedition 38 flight engineer, sets up the Microgravity Science Glovebox (MSG) for the Burning and Suppression of Solids (BASS-II) experiment in the Destiny laboratory of the International Space Station. BASS-II explores how different substances burn in microgravity with benefits for combustion on Earth and fire safety in space.

  10. PARIS II: DESIGNING GREENER SOLVENTS

    EPA Science Inventory

    PARIS II (the program for assisting the replacement of industrial solvents, version II), developed at the USEPA, is a unique software tool that can be used for customizing the design of replacement solvents and for the formulation of new solvents. This program helps users avoid ...

  11. National Synchrotron Light Source II

    ScienceCinema

    Steve Dierker

    2017-12-09

    The National Synchrotron Light Source II (NSLS-II) at the U.S. Department of Energy's Brookhaven National Laboratory is a proposed new state-of-the-art medium energy storage ring designed to deliver world-leading brightness and flux with top-off operation

  12. Photoinhibition of Photosystem II.

    PubMed

    Tyystjärvi, Esa

    2013-01-01

    Photoinhibition of Photosystem II (PSII) is the light-induced loss of PSII electron-transfer activity. Although photoinhibition has been studied for a long time, there is no consensus about its mechanism. On one hand, production of singlet oxygen ((1)O(2)) by PSII has promoted models in which this reactive oxygen species (ROS) is considered to act as the agent of photoinhibitory damage. These chemistry-based models have often not taken into account the photophysical features of photoinhibition-like light response and action spectrum. On the other hand, models that reproduce these basic photophysical features of the reaction have not considered the importance of data about ROS. In this chapter, it is shown that the evidence behind the chemistry-based models and the photophysically oriented models can be brought together to build a mechanism that confirms with all types of experimental data. A working hypothesis is proposed, starting with inhibition of the manganese complex by light. Inability of the manganese complex to reduce the primary donor promotes recombination between the oxidized primary donor and Q(A), the first stable quinone acceptor of PSII. (1)O(2) production due to this recombination may inhibit protein synthesis or spread the photoinhibitory damage to another PSII center. The production of (1)O(2) is transient because loss of activity of the oxygen-evolving complex induces an increase in the redox potential of Q(A), which lowers (1)O(2) production. Copyright © 2013 Elsevier Inc. All rights reserved.

  13. [Oculocutaneous type II tyrosinosis].

    PubMed

    Podglajen-Wecxsteen, O; Delaporte, E; Piette, F; le Flohic, X; Bergoend, H

    1993-01-01

    Richner-Hanhart syndrome, also called oculo-cutaneous tyrosinosis type II, is a recessive autosomal genodermatosis consecutive to a disorder of tyrosine metabolism. It presents as a varying association of palmo-plantar keratosis, bilateral keratitis and mental retardation. The authors report a new case which is atypical in that palmoplantar keratosis made a late appearance. The diagnosis was confirmed by the presence of hypertyrosinaemia, hypertyrosinuria and urinary excretion of phenolic acids, and the absence of hepato-renal lesion. Needle biopsy of the liver, which demonstrates the deficiency of soluble cytosolic tyrosine aminotransferase, is not indispensable to the diagnosis and was not performed in our patient. Treatment consisted of a dietary measure: a controlled phenylalanine and tyrosine intake to obtain a tyrosinaemia below 10 mg/100 ml. This resulted in a favourable and durable course of the oculo-cutaneous lesions. In case of isolated skin lesion, retinoids can be prescribed either alone of combined with a diet, making it less strict.

  14. Retrovirus Epidemiology Donor Study-II (REDS-II)

    ClinicalTrials.gov

    2016-04-14

    Acquired Immunodeficiency Syndrome; Blood Donors; Blood Transfusion; HIV Infections; HIV-1; HIV-2; HTLV-I; HTLV-II; Retroviridae Infections; Hepatitis, Viral, Human; Hepatitis B; Hepacivirus; West Nile Virus

  15. BASS-II Hardware Repair

    NASA Image and Video Library

    2014-03-27

    ISS039-E-005726 (27 March 2014) --- Expedition 39 Flight Engineer Rick Mastracchio performs inflight maintenance on an experiment called Burning and Suppression of Solids (BASS)-II. The investigation examines the burning and extinction characteristics of a wide variety of fuel samples in microgravity. The BASS-II experiment will guide strategies for materials flammability screening for use in spacecraft as well as provide valuable data on solid fuel burning behavior in microgravity. BASS-II results contribute to the combustion computational models used in the design of fire detection and suppression systems in microgravity and on Earth.

  16. Integrated Procurement Management System, Version II

    NASA Technical Reports Server (NTRS)

    Collier, L. J.

    1985-01-01

    Integrated Procurement Management System, Version II (IPMS II) is online/ batch system for collecting developing, managing and disseminating procurementrelated data at NASA Johnson Space Center. Portions of IPMS II adaptable to other procurement situations.

  17. The Monomeric Pentacyanocobaltate (II) Anion.

    ERIC Educational Resources Information Center

    Mosha, Donnati M. S.

    1982-01-01

    Laboratory procedures, background information, and discussion of experimental results are provided for the preparation of Thallium (I) Pentacyanocobaltate (II). The preparation of this pale green salt is carried out in an aqueous medium. (Author/JN)

  18. GeoGIS : phase II.

    DOT National Transportation Integrated Search

    2009-12-01

    A new web-based geotechnical Geographic Information System (GeoGIS) was developed and tested for the Alabama Department of Transportation (ALDOT) during Phase II of this research project. This web-based system stores geotechnical information about tr...

  19. Tier II Forms and Instructions

    EPA Pesticide Factsheets

    Facilities must comply with the new requirements on the Tier II emergency and hazardous chemical inventory form starting reporting year 2013, which is due by March 1, 2014. Some states may have specific requirements for reporting and submission.

  20. Mastracchio during BASS II Setup

    NASA Image and Video Library

    2014-02-12

    ISS038-E-046385 (12 Feb. 2014) --- NASA astronaut Rick Mastracchio, Expedition 38 flight engineer, uses a computer while setting up the Microgravity Science Glovebox (MSG) for the Burning and Suppression of Solids (BASS-II) experiment in the Destiny laboratory of the International Space Station. BASS-II explores how different substances burn in microgravity with benefits for combustion on Earth and fire safety in space.

  1. Clinically symptomatic heterozygous carnitine palmitoyltransferase II (CPT II) deficiency.

    PubMed

    Joshi, Pushpa Raj; Deschauer, Marcus; Zierz, Stephan

    2012-12-01

    Two symptomatic patients with heterozygous carnitine palmitoyltransferase II (CPT II) deficiency are reported. Patient 1, a 21-year-old female professional tennis player, suffered from exercise-induced attacks of muscle pain, burning sensations and proximal weakness. Patient 2, a 30-year-old male amateur marathon runner developed muscle cramps and rhabdomyolysis upon extensive exercise and insolation-induced fever. In both patients, the common p.S113L mutation was found in heterozygote state. No second mutation could be found upon sequencing of all the exons of CPT2 gene including exon-intron boundaries. Biochemically, residual CPT activity in muscle homogenate upon inhibition by malonyl-CoA and Triton-X-100 was intermediate between controls and patients with mutations on both alleles. Although CPT II deficiency is an autosomal recessive disorder, the reported patients indicate that heterozygotes might also have typical attacks of myalgia, pareses or rhabdomyolysis.

  2. The II Zw 40 Supernebula

    NASA Astrophysics Data System (ADS)

    Leitherer, C.; Byler, N.; Lee, J. C.; Levesque, E. M.

    2017-11-01

    We obtained HST COS G140L spectroscopy of the enigmatic nearby blue compact dwarf galaxy II Zw 40. The galaxy hosts a nuclear super star cluster with a luminosity 10 times that of 30 Doradus, the most powerful giant HII region in the Local Group. The super star cluster has been suggested to be the ionizing source of a ”supernebula” detected via its free-free radiation in the radio. The physical conditions, however, are much more complex, as demonstrated by the detection of the nebular He II and the mid-infrared line of [O IV] 25.9. These lines are unlikely to be related to hot stars and require a different powering source. II Zw 40 shares many similarities with the related blue compact dwarfs NGC 5253 and Henize 2-10. However, II Zw 40’s UV spectrum is unique in terms of the exceptional strength of He II 1640, O III 1663 and CIII 1909. We determined reddening, age, and the stellar initial mass function and perform a comparison with the local benchmark 30 Doradus. Photoionization modeling is used to determine the origin of the nebular lines as due to stellar ionization, shocks, or powering by a black hole.

  3. 24 CFR 202.12 - Title II.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Title II. 202.12 Section 202.12... INSTITUTIONS AND MORTGAGEES Title I and Title II Specific Requirements § 202.12 Title II. (a) Tiered pricing—(1... mortgagee approved for participation in Title II programs is notified by the Secretary that it had a rate of...

  4. Oscillator strengths for Si II

    NASA Astrophysics Data System (ADS)

    Luo, Ding; Pradhan, Anil K.; Shull, J. Michael

    1988-12-01

    New accurate results are presented for absorption oscillator strengths of Si II resonance lines. In these ab initio calculations, an extensive basis set of 67 electronic configuration are employed, including fine-structure states and relativistic effects in the Breit-Pauli approximation. For the strong Si II lines, good agreement is found with previous LS-coupling f-values of Dufton et al. (1983). Oscillator strengths of selected weaker lines disagree in some cases with empirically determined f-values by Shull, Snow, and York (1981) and by Van Buren (1986). The theoretical results are combined with curve-of-growth analyses of Copernicus and IUE data to yield a list of recommended Si II oscillator strengths consistent with the errors in both theoretical and observational analyses. These f-values have been used (Van Steenberg and Shull) for a Galactic survey of interstellar silicon abundances with the International Ultraviolet Explorer satellite.

  5. Oscillator strengths for Si II

    NASA Technical Reports Server (NTRS)

    Luo, Ding; Pradhan, Anil K.; Shull, J. Michael

    1988-01-01

    New accurate results are presented for absorption oscillator strengths of Si II resonance lines. In these ab initio calculations, an extensive basis set of 67 electronic configuration are employed, including fine-structure states and relativistic effects in the Breit-Pauli approximation. For the strong Si II lines, good agreement is found with previous LS-coupling f-values of Dufton et al. (1983). Oscillator strengths of selected weaker lines disagree in some cases with empirically determined f-values by Shull, Snow, and York (1981) and by Van Buren (1986). The theoretical results are combined with curve-of-growth analyses of Copernicus and IUE data to yield a list of recommended Si II oscillator strengths consistent with the errors in both theoretical and observational analyses. These f-values have been used (Van Steenberg and Shull) for a Galactic survey of interstellar silicon abundances with the International Ultraviolet Explorer satellite.

  6. Administrative Plans. STIP II (Skill Training Improvement Programs Round II).

    ERIC Educational Resources Information Center

    Los Angeles Community Coll. District, CA.

    Personnel policies, job responsibilities, and accounting procedures are summarized for the Los Angeles Community College District's Skill Training Improvement Programs (STIP II). This report first cites references to the established personnel and affirmative action procedures governing the program and then presents an organizational chart for the…

  7. Propulsion Systems for Aircraft. Aerospace Education II. Instructional Unit II.

    ERIC Educational Resources Information Center

    Elmer, James D.

    This curriculum guide accompanies another publication in the Aerospace Education II series entitled "Propulsion Systems for Aircraft." The guide includes specific guidelines for teachers on each chapter in the textbook. Suggestions are included for objectives (traditional and behavioral), suggested outline, orientation, suggested key…

  8. A new chelating resin for preconcentration and determination of Mn(II), Ni(II), Cu(II), Zn(II), Cd(II), and Pb(II) by flame atomic absorption spectrometry.

    PubMed

    Maheswari, Mohan A; Subramanian, Mandakolathur S

    2003-01-01

    A new polychelatogen, AXAD-16-1,2-diphenylethanolamine, was developed by chemically modifying Amberlite XAD-16 with 1,2-diphenylethanolamine to produce an effective metal-chelating functionality for the preconcentration of Mn(II), Ni(II), Cu(II), Zn(II), Cd(II), and Pb(II) and their determination by flame atomic absorption spectrometry. Various physiochemical parameters that influence the quantitative preconcentration and recovery of metal were optimized by both static and dynamic techniques. The resin showed superior extraction efficiency with high-metal loading capacity values of 0.73, 0.80, 0.77, 0.87, 0.74, and 0.81 mmol/g for Mn(II), Ni(II), Cu(II), Zn(II), Cd(II), and Pb(II), respectively. The system also showed rapid metal-ion extraction and stripping, with complete saturation in the sorbent phase within 15 min for all the metal ions. The optimum condition for effective metal-ion extraction was found to be a neutral pH, which is a great advantage in the preconcentration of trace metal ions from natural water samples without any chemical pretreatment of the sample. The resin also demonstrated exclusive ion selectivity toward targeted metal ions by showing greater resistivity to various complexing species and more common metal ions during analyte concentration, which ultimately led to high preconcentration factors of 700 for Cu(II); 600 for Mn(II), Ni(II), and Zn(II); and 500 for Cd(II) and Pb(II), arising from a larger sample breakthrough volume. The lower limits of metal-ion detection were 7 ng/mL for Mn(II) and Ni(II); 5 ng/mL for Cu(II), Zn(II), and Cd(II), and 10 ng/mL for Pb(II). The developed resin was successful in preconcentrating metal ions from synthetic and real water samples, multivitamin-multimineral tablets, and curry leaves (Murraya koenigii) with relative standard deviations of < or = 3.0% for all analytical measurements, which demonstrated its practical utility.

  9. 40 CFR Table II-1 to Subpart II of... - Emission Factors

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 22 2013-07-01 2013-07-01 false Emission Factors II Table II-1 to Subpart II of Part 98 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Industrial Wastewater Treatment Pt. 98, Subpt. II, Table II-1...

  10. 40 CFR Table II-1 to Subpart II of... - Emission Factors

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 21 2014-07-01 2014-07-01 false Emission Factors II Table II-1 to Subpart II of Part 98 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Industrial Wastewater Treatment Pt. 98, Subpt. II, Table II-1...

  11. Application Programming in AWIPS II

    NASA Technical Reports Server (NTRS)

    Smit, Matt; McGrath, Kevin; Burks, Jason; Carcione, Brian

    2012-01-01

    Since its inception almost 8 years ago, NASA's Short-term Prediction Research and Transition (SPoRT) Center has integrated NASA data into the National Weather Service's decision support system (DSS) the Advanced Weather Interactive Processing System (AWIPS). SPoRT has, in some instances, had to shape and transform data sets into various formats and manipulate configurations to visualize them in AWIPS. With the advent of the next generation of DSS, AWIPS II, developers will be able to develop their own plugins to handle any type of data. Raytheon is developing AWIPS II to be a more extensible package written mainly in Java, and built around a Service Oriented Architecture. A plugin architecture will allow users to install their own code modules, and (if all the rules have been properly followed) they will work hand-in-hand with AWIPS II as if it were originally built in. Users can bring in new datasets with existing plugins, tweak plugins to handle a nuance or desired new functionality, or create an entirely new visualization layout for a new dataset. SPoRT is developing plugins to ensure its existing NASA data will be ready for AWIPS II when it is delivered, and to prepare for the future of new instruments on upcoming satellites.

  12. 40 K Fastrac II Test

    NASA Technical Reports Server (NTRS)

    1997-01-01

    A 40 K Fastrac II duration test performed at Marshall Test Stand 116. The purpose of this test was to gauge the length of time between contact of TEA (Triethylenealuminum) and LOX (liquid oxygen) as an ignitor for the Fastrac engine.

  13. RARE II: The Administration's View

    ERIC Educational Resources Information Center

    Cutler, M. Rupert

    1977-01-01

    RARE II is a new Roadless Area Review and Evaluation of the National Forest system. Administrators are attempting to inventory existing wilderness areas and to determine criteria for setting aside additional ones. This information will be used for the required 1980 update of the national assessment of forests and rangelands. (MA)

  14. Grad II: An Impact Study.

    ERIC Educational Resources Information Center

    Johnson, Richard P.; Mayberry, Maurice E.

    1981-01-01

    Evaluates the impact of an integrated computer program called GRAD II (Graduate Resume Accumulation and Distribution) which allows a direct communication link between job-seeking students and potential employers. Response was generally favorable although a better mix of employers was needed. (JAC)

  15. Outcome in tyrosinaemia type II.

    PubMed Central

    Barr, D G; Kirk, J M; Laing, S C

    1991-01-01

    Tyrosinaemia type II was diagnosed in a boy with failure to thrive and in his sister on neonatal screening. On diet the outcome, at 12 and 10 years respectively, has been excellent in respect of oculocutaneous sequelae, growth, and psychomotor development, contrasting with the generally unfavourable outcome in most reported cases. PMID:1953015

  16. National Synchrotron Light Source II

    ScienceCinema

    Hill, John; Dooryhee, Eric; Wilkins, Stuart; Miller, Lisa; Chu, Yong

    2018-01-16

    NSLS-II is a synchrotron light source helping researchers explore solutions to the grand energy challenges faced by the nation, and open up new regimes of scientific discovery that will pave the way to discoveries in physics, chemistry, and biology — advances that will ultimately enhance national security and help drive the development of abundant, safe, and clean energy technologies.

  17. INTERMEDIATE CHINESE READER. PART II.

    ERIC Educational Resources Information Center

    DE FRANCIS, JOHN; AND OTHERS

    THE SECOND OF TWO VOLUMES, PART II CONTAINS LESSONS 16 TO 30 AND SHORT "SUPPLEMENTARY LESSONS ON SIMPLIFIED CHARACTERS." THESE LESSONS, WHICH FOLLOW THE SAME FORMAT AS THOSE IN PART I, ARE APPENDED BY--(1) A STROKE-ORDER CHART FOR THOSE CHARACTERS STUDENTS MIGHT FIND DIFFICULT TO WRITE, (2) THREE SUMMARY CHARTS LISTING CHARACTERS BY…

  18. Synthesis, spectroscopic, antimicrobial and DNA cleavage studies of new Co(II), Ni(II), Cu(II), Cd(II), Zn(II) and Hg(II) complexes with naphthofuran-2-carbohydrazide Schiff base

    NASA Astrophysics Data System (ADS)

    Halli, Madappa B.; Sumathi, R. B.

    2012-08-01

    A series of Co(II), Ni(II), Cu(II), Cd(II), Zn(II) and Hg(II) complexes have been synthesized with newly synthesized Schiff base derived from naphthofuran-2-carbohydrazide and cinnamaldehyde. The elemental analyses of the complexes are confined to the stoichiometry of the type MLCl2 [M = Co(II) and Cu(II)], ML2Cl2 [M = Ni(II), Cd(II), Zn(II) and Hg(II)] respectively, where L is Schiff base ligand. Structures have been proposed from elemental analyses, IR, electronic, mass, 1H NMR, ESR spectral data, magnetic, and thermal studies. The measured low molar conductance values in DMF indicate that the complexes are non-electrolytes. Spectroscopic studies suggest coordination occurs through azomethine nitrogen and carbonyl oxygen of the ligand with the metal ions. The Schiff base and its complexes have been screened for their antibacterial (Escherichia coli, Staphylococcus aureus, Bacillus subtilis and Salmonella typhi) and antifungal (Aspergillus niger, Aspergillus flavus, Cladosporium and Candida albicans) activities by minimum inhibitory concentration (MIC) method. The DNA cleavage studies by agarose gel electrophoresis method was studied for all the complexes.

  19. Comparative studies of aerosol extinction measurements made by the SAM II and SAGE II satellite experiments

    NASA Technical Reports Server (NTRS)

    Yue, Glenn K.; Mccormick, M. P.; Chu, W. P.; Wang, P.; Osborn, M. T.

    1989-01-01

    Results from the Stratospheric Aerosol Measurement (SAM) II and Stratospheric Aerosol and Gas Experiment (SAGE) II are compared for measurement locations which are coincident in time and space. At 1.0 micron, the SAM II and SAGE II aerosol extinction profiles are similar within their measurement errors. In addition, sunrise and sunset aerosol extinction data at four different wavelengths are compared for occasions when the SAGE II and SAM II measurements are nearly coincident in space and about 12 hours apart.

  20. Binding Selectivity of Methanobactin from Methylosinus trichosporium OB3b for Copper(I), Silver(I), Zinc(II), Nickel(II), Cobalt(II), Manganese(II), Lead(II), and Iron(II)

    NASA Astrophysics Data System (ADS)

    McCabe, Jacob W.; Vangala, Rajpal; Angel, Laurence A.

    2017-12-01

    Methanobactin (Mb) from Methylosinus trichosporium OB3b is a member of a class of metal binding peptides identified in methanotrophic bacteria. Mb will selectively bind and reduce Cu(II) to Cu(I), and is thought to mediate the acquisition of the copper cofactor for the enzyme methane monooxygenase. These copper chelating properties of Mb make it potentially useful as a chelating agent for treatment of diseases where copper plays a role including Wilson's disease, cancers, and neurodegenerative diseases. Utilizing traveling wave ion mobility-mass spectrometry (TWIMS), the competition for the Mb copper binding site from Ag(I), Pb(II), Co(II), Fe(II), Mn(II), Ni(II), and Zn(II) has been determined by a series of metal ion titrations, pH titrations, and metal ion displacement titrations. The TWIMS analyses allowed for the explicit identification and quantification of all the individual Mb species present during the titrations and measured their collision cross-sections and collision-induced dissociation patterns. The results showed Ag(I) and Ni(II) could irreversibly bind to Mb and not be effectively displaced by Cu(I), whereas Ag(I) could also partially displace Cu(I) from the Mb complex. At pH ≈ 6.5, the Mb binding selectivity follows the order Ag(I)≈Cu(I)>Ni(II)≈Zn(II)>Co(II)>>Mn(II)≈Pb(II)>Fe(II), and at pH 7.5 to 10.4 the order is Ag(I)>Cu(I)>Ni(II)>Co(II)>Zn(II)>Mn(II)≈Pb(II)>Fe(II). Breakdown curves of the disulfide reduced Cu(I) and Ag(I) complexes showed a correlation existed between their relative stability and their compact folded structure indicated by their CCS. Fluorescence spectroscopy, which allowed the determination of the binding constant, compared well with the TWIMS analyses, with the exception of the Ni(II) complex. [Figure not available: see fulltext.

  1. Type II Supernova Spectral Diversity. II. Spectroscopic and Photometric Correlations

    NASA Astrophysics Data System (ADS)

    Gutiérrez, Claudia P.; Anderson, Joseph P.; Hamuy, Mario; González-Gaitan, Santiago; Galbany, Lluis; Dessart, Luc; Stritzinger, Maximilian D.; Phillips, Mark M.; Morrell, Nidia; Folatelli, Gastón

    2017-11-01

    We present an analysis of observed trends and correlations between a large range of spectral and photometric parameters of more than 100 type II supernovae (SNe II), during the photospheric phase. We define a common epoch for all SNe of 50 days post-explosion, where the majority of the sample is likely to be under similar physical conditions. Several correlation matrices are produced to search for interesting trends between more than 30 distinct light-curve and spectral properties that characterize the diversity of SNe II. Overall, SNe with higher expansion velocities are brighter, have more rapidly declining light curves, shorter plateau durations, and higher 56Ni masses. Using a larger sample than previous studies, we argue that “Pd”—the plateau duration from the transition of the initial to “plateau” decline rates to the end of the “plateau”—is a better indicator of the hydrogen envelope mass than the traditionally used optically thick phase duration (OPTd: explosion epoch to end of plateau). This argument is supported by the fact that Pd also correlates with s 3, the light-curve decline rate at late times: lower Pd values correlate with larger s 3 decline rates. Large s 3 decline rates are likely related to lower envelope masses, which enables gamma-ray escape. We also find a significant anticorrelation between Pd and s 2 (the plateau decline rate), confirming the long standing hypothesis that faster declining SNe II (SNe IIL) are the result of explosions with lower hydrogen envelope masses and therefore have shorter Pd values. This paper includes data gathered with the 6.5 m Magellan Telescopes located at Las Campanas Observatory, Chile; and the Gemini Observatory, Cerro Pachon, Chile (Gemini Program GS- 2008B-Q-56). Based on observations collected at the European Organisation for Astronomical Research in the Southern Hemisphere, Chile (ESO Programs 076.A-0156, 078.D-0048, 080.A-0516, and 082.A-0526).

  2. Research Summary No. 36-5, Volume II. Volume II

    NASA Technical Reports Server (NTRS)

    1960-01-01

    The Research Summary is a bimonthly report of supporting research and development conducted at the Jet Propulsion Laboratory. This periodical is issued in three volumes. Volume I contains summaries of the work accomplished by the Space Sciences, Systems, Guidance and Control, and Telecommunications Divisions of the Laboratory. Volume II contains summaries of the work accomplished by the Physical Sciences, Engineering Mechanics, Engineering Facilities, and Propulsion Divisions. All work of a classified nature is contained in Volume Ill.

  3. Research Summary No. 36-6, Volume II. Volume II

    NASA Technical Reports Server (NTRS)

    1961-01-01

    The Research Summary is a bimonthly report of supporting research and development conducted at the Jet Propulsion Laboratory. This periodical is issued in three volumes. Volume I contains summaries of the work accomplished by the Space Sciences, Systems, Guidance and Control, and Telecommunications Divisions of the Laboratory. Volume II contains summaries of the work accomplished by the Physical Sciences, Engineering Mechanics, Engineering Facilities, and Propulsion Divisions. All work of a classified nature is contained in Volume Ill.

  4. Cytosolic Ni(II) Sensor in Cyanobacterium

    PubMed Central

    Foster, Andrew W.; Patterson, Carl J.; Pernil, Rafael; Hess, Corinna R.; Robinson, Nigel J.

    2012-01-01

    Efflux of surplus Ni(II) across the outer and inner membranes of Synechocystis PCC 6803 is mediated by the Nrs system under the control of a sensor of periplasmic Ni(II), NrsS. Here, we show that the product of ORF sll0176, which encodes a CsoR/RcnR-like protein now designated InrS (for internal nickel-responsive sensor), represses nrsD (NrsD is deduced to efflux Ni(II) across the inner membrane) from a cryptic promoter between the final two ORFs in the nrs operon. Transcripts initiated from the newly identified nrsD promoter accumulate in response to nickel or cobalt but not copper, and recombinant InrS forms specific, Ni(II)-inhibited complexes with the nrsD promoter region. Metal-dependent difference spectra of Ni(II)- and Cu(I)-InrS are similar to Cu(I)-sensing CsoR and dissimilar to Ni(II)/Co(II)-sensing RcnR, consistent with factors beyond the primary coordination sphere switching metal selectivity. Competition with chelators mag-fura-2, nitrilotriacetic acid, EDTA, and EGTA estimate KD Ni(II) for the tightest site of InrS as 2.05 (±1.5) × 10−14 m, and weaker KD Ni(II) for the cells' metal sensors of other types: Zn(II) co-repressor Zur, Co(II) activator CoaR, and Zn(II) derepressor ZiaR. Ni(II) transfer to InrS occurs upon addition to Ni(II) forms of each other sensor. InrS binds Ni(II) sufficiently tightly to derepress Ni(II) export at concentrations below KD Ni(II) of the other sensors. PMID:22356910

  5. PERMEABILITY OF BACTERIAL SPORES II.

    PubMed Central

    Gerhardt, Philipp; Black, S. H.

    1961-01-01

    Gerhardt, Philipp (University of Michigan, Ann Arbor) and S. H. Black. Permeability of bacterial spores. II. Molecular variables affecting solute permeation. J. Bacteriol. 82:750–760. 1961.—More than 100 compounds were tested for their uptake by dormant spores of a bacillus. The extent of penetration was found to be dependent on at least three molecular properties: (i) The dissociation of electrolytes usually resulted in high or low uptake predictable from their charge. (ii) Lipid insolubility restricted permeation of small molecules. (iii) The molecular weight of unsubstituted glycol and sugar polymers exponentially limited penetration to eventual exclusion at mol wt above 160,000. The results were plotted as a generalized curve, calculations from which permitted an interpretation that the effective spore surface contains pores varying in diameter from 10 to 200 A. PMID:13897940

  6. Genetics Home Reference: carnitine palmitoyltransferase II deficiency

    MedlinePlus

    ... be triggered by exercise, stress, exposure to extreme temperatures, infections, or fasting. The first episode usually occurs ... II (CPT II) deficiency. J Neurol Sci. 2008 Mar 15;266(1-2):97-103. Epub 2007 ...

  7. ADIEM II end terminal for concrete barrier

    DOT National Transportation Integrated Search

    2001-03-01

    On September 9, 1997, an ADIEM II (Advanced Dynamic Impact Extension Module) was installed on Interstate 5 near Salem, Oregon. The ADIEM II offered a redirecting, energy-absorbing crash cushion and end treatment for portable and permanent protection ...

  8. Preliminary Results from ARCADE II

    NASA Astrophysics Data System (ADS)

    Fixsen, Dale J.; Kogut, A.; Limon, M.; Wollack, E.; Mirel, P.; Singal, J.; Lubin, P.; Levin, S.; Seiffert, M.

    2006-12-01

    The ARCADE II instrument was designed to compare the cosmic microwave background spectrum to a blackbody spectrum at long (cm) wavelengths where the first stars are predicted to distort the ideal spectrum of the big bang. Reionization generates larger relative distortions at low frequencies. ARCADE II observed at 5 frequencies (3, 8, 10, 30 & 90 GHz). Each radiometer has a corrugated feed horn, a Dicke switch, internal calibrator, and amplifier mounted in an open liquid helium Dewar. The Dewar is 1.5 m in diameter and 1.8 m deep. The ARCADE II employs a double difference scheme to control systematic errors, similar to the design of the COBE FIRAS instrument. The input to each radiometer is switched at 75 Hz between its internal calibrator and its horn antenna. The horn can observe either the sky or an external calibrator which is temperature controled to match the temperature of the CMB. Detailed thermal charactorization of the external calibrator is enabled by 35 RuO thermometers embedded in the calibrator. The external calibrator has demonstrated 2.725 K operation even in the residual atmosphere at balloon altitudes. The ARCADE II was launched on a balloon from Palestine TX on 2006 July 28. Approximately 3 hours of data were obtained, at 115000 feet, that allow calibration of the instrument and precise measurements of the spectrum of the CMB down to 3 GHz. The 12 degree beams of the radiometers were swept across the sky to show the Galaxy as well as the CMB. Pictures taken in flight show that cryogenic surfaces open to the sky can remain relatively frost free for hours with proper helium gas flow.

  9. Light echoes - Type II supernovae

    NASA Technical Reports Server (NTRS)

    Schaefer, Bradley E.

    1987-01-01

    Type II supernovae (SNs) light curves show a remarkable range of shapes. Data have been collected for the 12 Type II SNs that have light curve information for more than four months past maximum. Contrary to previous reports, it is found that (1) the decay rate after 100 days past maximum varies by almost an order of magnitude and (2) the light curve shapes are not bimodally distributed, but actually form a continuum. In addition, it is found that the extinctions to the SNs are related to the light curve shapes. This implies that the absorbing dust is local to the SNs. The dust is likely to be part of a circumstellar shell emitted by the SN progenitor that Dwek (1983) has used to explain infrared echoes. The optical depth of the shell can get quite large. In such cases, it is found that the photons scattered and delayed by reflection off dust grains will dominate the light curve several months after peak brightness. This 'light echo' offers a straightforward explanation of the diversity of Type II SN light curves.

  10. Synthesis, spectral, thermal and antimicrobial studies on cobalt(II), nickel(II), copper(II), zinc(II) and palladium(II) complexes containing thiosemicarbazone ligand

    NASA Astrophysics Data System (ADS)

    El-Sawaf, Ayman K.; El-Essawy, Farag; Nassar, Amal A.; El-Samanody, El-Sayed A.

    2018-04-01

    The coordination characteristic of new N4-morpholinyl isatin-3-thiosemicarbazone (HL) towards Co(II), Ni(II), Cu(II), Zn(II) and Pd(II) has been studies. The structures of the complexes were described by elemental analyses, molar conductivity, magnetic, thermal and spectral (IR, UV-Vis, 1H and 13C NMR and ESR) studies. On the basis of analytical and spectral studies the ligand behaves as monobasic tridentate ONS donor forming two five membered rings towards cobalt, copper and palladium and afforded complexes of the kind [M(L)X], (Mdbnd Co, Cu or Pd; Xdbnd Cl, Br or OAc). Whereas the ligand bound to NiCl2 as neutral tridentate ONS donor and with ZnCl2 as neutral bidentate NS donor. The newly synthesized thiosemicarbazone ligand and some of its complexes were examined for antimicrobial activity against 2 gram negative bacterial strains (Escherichia coli Pseudomonas and aeruginosa), 2 gram positive bacterial strains (Streptococcus pneumoniae and Staphylococcus aureus)} and two Pathogenic fungi (Aspergillus fumigatus and Candida albicans). All metal complexes possess higher antimicrobial activity comparing with the free thiosemicarbazone ligand. The high potent activities of the complexes may arise from the coordination and chelation, which tends to make metal complexes act as more controlling and potent antimicrobial agents, thus hindering the growing of the microorganisms. The antimicrobial results also show that copper bromide complex is better antimicrobial agent as compared to the Schiff base and its metal complexes.

  11. Biosorption of Cu(II), Zn(II), Ni(II) and Pb(II) ions by cross-linked metal-imprinted chitosans with epichlorohydrin.

    PubMed

    Chen, Chia-Yun; Yang, Cheng-Yu; Chen, Arh-Hwang

    2011-03-01

    Cross-linked metal-imprinted chitosan microparticles were prepared from chitosan, using four metals (Cu(II), Zn(II), Ni(II), and Pb(II)) as templates, and epichlorohydrin as the cross-linker. The microparticles were characterized by Fourier transform infrared spectroscopy, solid state (13)C nuclear magnetic resonance spectroscopy, and energy-dispersive X-ray spectroscopy. They were used for comparative biosorption of Cu(II), Zn(II), Ni(II) and Pb(II) ions in an aqueous solution. The results showed that the sorption capacities of Cu(II), Zn(II), Ni(II), and Pb(II) on the templated microparticles increased from 25 to 74%, 13 to 46%, 41 to 57%, and 12 to 43%, respectively, as compared to the microparticles without metal ion templates. The dynamic study showed that the sorption process followed the second-order kinetic equation. Three sorption models, Langmuir, Freundlich, and Dubinin-Radushkevich, were applied to the equilibrium isotherm data. The result showed that the Langmuir isotherm equation best fitted for monolayer sorption processes. Furthermore, the microparticles can be regenerated and reused for the metal removal. Copyright © 2010 Elsevier Ltd. All rights reserved.

  12. Macrocyclic receptor showing extremely high Sr(II)/Ca(II) and Pb(II)/Ca(II) selectivities with potential application in chelation treatment of metal intoxication.

    PubMed

    Ferreirós-Martínez, Raquel; Esteban-Gómez, David; Tóth, Éva; de Blas, Andrés; Platas-Iglesias, Carlos; Rodríguez-Blas, Teresa

    2011-04-18

    Herein we report a detailed investigation of the complexation properties of the macrocyclic decadentate receptor N,N'-Bis[(6-carboxy-2-pyridil)methyl]-4,13-diaza-18-crown-6 (H(2)bp18c6) toward different divalent metal ions [Zn(II), Cd(II), Pb(II), Sr(II), and Ca(II)] in aqueous solution. We have found that this ligand is especially suited for the complexation of large metal ions such as Sr(II) and Pb(II), which results in very high Pb(II)/Ca(II) and Pb(II)/Zn(II) selectivities (in fact, higher than those found for ligands widely used for the treatment of lead poisoning such as ethylenediaminetetraacetic acid (edta)), as well as in the highest Sr(II)/Ca(II) selectivity reported so far. These results have been rationalized on the basis of the structure of the complexes. X-ray crystal diffraction, (1)H and (13)C NMR spectroscopy, as well as theoretical calculations at the density functional theory (B3LYP) level have been performed. Our results indicate that for large metal ions such as Pb(II) and Sr(II) the most stable conformation is Δ(δλδ)(δλδ), while for Ca(II) our calculations predict the Δ(λδλ)(λδλ) form being the most stable one. The selectivity that bp18c6(2-) shows for Sr(II) over Ca(II) can be attributed to a better fit between the large Sr(II) ions and the relatively large crown fragment of the ligand. The X-ray crystal structure of the Pb(II) complex shows that the Δ(δλδ)(δλδ) conformation observed in solution is also maintained in the solid state. The Pb(II) ion is endocyclically coordinated, being directly bound to the 10 donor atoms of the ligand. The bond distances to the donor atoms of the pendant arms (2.55-2.60 Å) are substantially shorter than those between the metal ion and the donor atoms of the crown moiety (2.92-3.04 Å). This is a typical situation observed for the so-called hemidirected compounds, in which the Pb(II) lone pair is stereochemically active. The X-ray structures of the Zn(II) and Cd(II) complexes show that

  13. Spectroscopic and mycological studies of Co(II), Ni(II) and Cu(II) complexes with 4-aminoantipyrine derivative

    NASA Astrophysics Data System (ADS)

    Sharma, Amit Kumar; Chandra, Sulekh

    2011-10-01

    Complexes of the type [M(L)X 2], where M = Co(II), Ni(II) and Cu(II), have been synthesized with novel NO-donor Schiff's base ligand, 1,4-diformylpiperazine bis(4-imino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one) which is obtained by the acid catalyzed condensation of 1,4-diformylpiperazine with 4-aminoantipyrine. The elemental analyses, molar conductance measurements, magnetic susceptibility measurements, IR, UV, NMR, mass and EPR studies of the compounds led to the conclusion that the ligand acts as tetradentate chelate. The Schiff's base ligand forms hexacoordinated complexes having octahedral geometry for Ni(II) and tetragonal geometry for Co(II) and Cu(II) complexes. The mycological studies of the compounds were examined against the several opportunistic pathogens, i.e., Alternaria brassicae, Aspergillus niger and Fusarium oxysporum. The Cu(II) complexes were found to have most fungicidal behavior.

  14. The Purdue University Get Away Special II (PUGAS II)

    NASA Technical Reports Server (NTRS)

    Olenski, Christopher; Crocker, Alan R.; Stubbings, Beth; Mccormick, Laurie; Andersen, Paul K.

    1988-01-01

    The Purdue University Get Away Special Project (PUGAS) is a student-run organization dedicated to preparing payloads for flight on NASA's space shuttle. The first such payload (PUGAS I) flew on Challenger in 1983. The second payload (PUGAS II) should be ready by the end of 1988 and will include three experiments. The first experiment will involve the production of tin metal foam under microgravity conditions. The second experiment will focus on the desorption of water from carbon-epoxy composite materials. The third experiment will use a solid polymeric material to detect radiation in space.

  15. Synthesis, spectral characterization and biological evaluation of Mn(II), Co(II), Ni(II), Cu(II), Zn(II) and Cd(II) complexes with thiosemicarbazone ending by pyrazole and pyridyl rings.

    PubMed

    Yousef, T A; Abu El-Reash, G M; Al-Jahdali, M; El-Rakhawy, El-Bastawesy R

    2014-08-14

    Here we present the synthesis of the new Mn(II), Co(II), Ni(II), Cu(II), Zn(II) and Cd(II) complexes with chelating ligand (Z)-(2-((1,3-diphenyl-1H-pyrazol-4-yl)methylene) hydrazinyl)(pyridin-2-ylamino)methanethiol. All the complexes were characterized by elemental analysis, IR, (1)H NMR, UV-vis, magnetic susceptibility measurements and EPR spectral studies. IR spectra of complexes showed that the ligand behaves as NN neutral bidentate, NSN mononegative tridentate and NSNN mononegative tetradentate. The electronic spectra and the magnetic measurements suggested the octahedral geometry for all complexes as well as the EPR confirmed the tetragonal distorted octahedral for Cu(II) complex. Cd(II) complex showed the highest inhibitory antioxidant activity either using ABTS method. The SOD-like activity exhibited those Cd(II) and Zn(II) complexes have strong antioxidative properties. We tested the synthesized compounds for antitumor activity and showed that the ability to kill liver (HePG2) and breast (MCF-7) cancer cells definitely. Copyright © 2014 Elsevier B.V. All rights reserved.

  16. Synthesis of tin (II) oxide from tin (II) oxohydroxide

    NASA Astrophysics Data System (ADS)

    Kuznetsova, Svetlana; Lisitsa, Konstantin

    2017-11-01

    Sufficiently limited use of tin (II) oxide is associated with the difficulties of its preparation without impurities of tin (IV) oxide. Understanding the cause of the oxidation process will make it possible to develop methods for obtaining SnO without impurities. The influence of ammonium chloride concentration in the suspension on the oxide composition was investigated. The temperature of oxidation (400 °C) on the air and temperature decomposition in the argon (350 °C) of Sn6O4(OH)4 in the solid phase were determined by the thermal analysis method. The decomposition temperature of the oxyhydroxide in the suspension of ammonium chloride does not exceed 100 °C. An increase in the content of ammonium chloride in an aqueous solution leads to an increase i n the solubility of oxohydroxide and leads to an increase in pH. The suspensions of Sn6O4(OH)4 were subjected to heat treatment on a sand bath and under microwave irradiation. Samples of tin oxide were obtained. The quantitative composition of the mixture of tin oxides was determined. The research also highlights emphasizes that the oxidation of tin (II) to tin (IV) is associated with the dissolved oxygen content in the suspension.

  17. Structural alteration of hexagonal birnessite by aqueous Mn(II): Impacts on Ni(II) sorption

    SciTech Connect

    Lefkowitz, Joshua P.; Elzinga, Evert J.

    2017-09-01

    We studied the impacts of aqueous Mn(II) (1 mM) on the sorption of Ni(II) (200 μM) by hexagonal birnessite (0.1 g L- 1) at pH 6.5 and 7.5 with batch experiments and XRD, ATR-FTIR and Ni K-edge EXAFS analyses. In the absence of Mn(II)aq, sorbed Ni(II) was coordinated predominantly as triple corner-sharing complexes at layer vacancies at both pH values. Introduction of Mn(II)aq into Ni(II)-birnessite suspensions at pH 6.5 caused Ni(II) desorption and led to the formation of edge-sharing Ni(II) complexes. This was attributed to competitive displacement of Ni(II) from layer vacancies by either Mn(II) or by Mn(III) formed throughmore » interfacial Mn(II)-Mn(IV) comproportionation, and/or incorporation of Ni(II) into the birnessite lattice promoted by Mn(II)-catalyzed recrystallization of the sorbent. Similar to Mn(II)aq, the presence of HEPES or MES caused the formation of edge-sharing Ni(II) sorption complexes in Ni(II)-birnessite suspensions, which was attributed to partial reduction of the sorbent by the buffers. At pH 7.5, interaction with aqueous Mn(II) caused reductive transformation of birnessite into secondary feitknechtite that incorporated Ni(II), enhancing removal of Ni(II) from solution. These results demonstrate that reductive alteration of phyllomanganates may significantly affect the speciation and solubility of Ni(II) in anoxic and suboxic environments.« less

  18. Delta II JPSS-1 Rollback

    NASA Image and Video Library

    2017-11-13

    At Vandenberg Air Force Base in California, the gantry rolls back at Space Launch Complex 2 in preparation for the liftoff of the Joint Polar Satellite System-1, or JPSS-1, spacecraft. The United Launch Alliance Delta II rocket now is poised to boost the satellite to a polar orbit. Built by Ball Aerospace and Technologies Corp. of Boulder, Colorado, JPSS is the first in a series four next-generation environmental satellites in a collaborative program between NOAA and NASA. The satellite is scheduled to liftoff at 1:47 a.m. PST (4:47 a.m. EST), on Nov. 14, 2017.

  19. Delta II JPSS-1 Liftoff

    NASA Image and Video Library

    2017-11-18

    A United Launch Alliance Delta II rocket lifts off from Space Launch Complex 2 at Vandenberg Air Force Base in California carrying the Joint Polar Satellite System-1, or JPSS-1, spacecraft. Built by Ball Aerospace and Technologies Corp. of Boulder, Colorado, JPSS is the first in a series four next-generation environmental satellites in a collaborative program between NOAA and NASA. JPSS-1 will gather measurements of atmospheric, terrestrial and oceanic conditions, including sea and land surface temperatures, vegetation, clouds, rainfall, snow and ice cover, fire locations, atmospheric temperature, water vapor and ozone. Liftoff was at 1:47 a.m. PST (4:47 a.m. EST).

  20. CLEO II silicon vertex detector

    NASA Astrophysics Data System (ADS)

    Gaidarev, P.

    1996-02-01

    A Silicon Vertex Detector (SVD) has been commissioned for the CLEO II experiment at Cornell Electron Storage Ring (CESR). The SVD is a three layer tracker using double-sided AC coupled silicon detectors. Detectors are mounted on fiber composite support and read out at the ends, removing all electronics from the tracking volume. CAMEX and JAMEX chips are used to read out 26 208 channels. The condition of detectors and electronics is monitored by a slow control system. A moving shields system provides extra protection from the synchrotron radiation. We present an overview of the design, construction and operation of the SVD.

  1. Solid Phase Extraction of Trace Al(III), Fe(II), Co(II), Cu(II), Cd(II) and Pb(II) Ions in Beverages on Functionalized Polymer Microspheres Prior to Flame Atomic Absorption Spectrometric Determinations.

    PubMed

    Berber, Hale; Alpdogan, Güzin

    2017-01-01

    In this study, poly(glycidyl methacrylate-methyl methacrylate-divinylbenzene) was synthesized in the form of microspheres, and then functionalized by 2-aminobenzothiazole ligand. The sorption properties of these functionalized microspheres were investigated for separation, preconcentration and determination of Al(III), Fe(II), Co(II), Cu(II), Cd(II) and Pb(II) ions using flame atomic absorption spectrometry. The optimum pH values for quantitative sorption were 2 - 4, 5 - 8, 6 - 8, 4 - 6, 2 - 6 and 2 - 3 for Al(III), Fe(II), Co(II), Cu(II), Cd(II) and Pb(II), respectively, and also the highest sorption capacity of the functionalized microspheres was found to be for Cu(II) with the value of 1.87 mmol g -1 . The detection limits (3σ; N = 6) obtained for the studied metals in the optimal conditions were observed in the range of 0.26 - 2.20 μg L -1 . The proposed method was successfully applied to different beverage samples for the determination of Al(III), Fe(II), Co(II), Cu(II), Cd(II) and Pb(II) ions, with the relative standard deviation of <3.7%.

  2. Diet History Questionnaire II FAQs | EGRP/DCCPS/NCI/NIH

    Cancer.gov

    Answers to general questions about the Diet History Questionnaire II (DHQ II), as well as those related to DHQ II administration, validation, scanning, nutrient estimates, calculations, DHQ II modification, data quality, and more.

  3. The SRC-II process

    NASA Astrophysics Data System (ADS)

    Schmid, B. K.; Jackson, D. M.

    1981-03-01

    The Solvent Refined Coal (SRC-II) process which produces low-sulfur distillate fuel oil from coal is discussed. The process dissolves coal in a process-derived solvent at elevated temperature and pressure in the presence of hydrogen, separates the undissolved mineral residue, then recovers the original solvent by vacuum distillation. The distillate fuel oil produced is for use largely as a nonpolluting fuel for generating electrical power and steam and is expected to be competitive with petroleum fuels during the 1980s. During this period, the SRC-II fuel oil is expected to be attractive compared with combustion of coal with flue gas desulfurization in U.S. East Coast oil-burning power plants, as well as in small and medium-sized industrial boilers. The substantial quantities of methane, light hydrocarbons and naphtha produced by the process have value as feedstocks for preparation of pipeline gas, ethylene and high-octane unleaded gasoline, and can replace petroleum fractions in many applications. The liquid and gas products from a future large-scale plant, such as the 6000 t/day plant planned for Morgantown, West Virginia, are expected to have an overall selling price of $4.25 to $4.75/GJ.

  4. THE SPECTRUM OF Fe II

    SciTech Connect

    Nave, Gillian; Johansson, Sveneric, E-mail: gillian.nave@nist.gov

    2013-01-15

    The spectrum of singly ionized iron (Fe II) has been recorded using high-resolution Fourier transform (FT) and grating spectroscopy over the wavelength range 900 A to 5.5 {mu}m. The spectra were observed in high-current continuous and pulsed hollow cathode discharges using FT spectrometers at the Kitt Peak National Observatory, Tucson, AZ and Imperial College, London and with the 10.7 m Normal Incidence Spectrograph at the National Institute of Standards and Technology. Roughly 12,900 lines were classified using 1027 energy levels of Fe II that were optimized to measured wavenumbers. The wavenumber uncertainties of lines in the FT spectra range frommore » 10{sup -4} cm{sup -1} for strong lines around 4 {mu}m to 0.05 cm{sup -1} for weaker lines around 1500 A. The wavelength uncertainty of lines in the grating spectra is 0.005 A. The ionization energy of (130,655.4 {+-} 0.4) cm{sup -1} was estimated from the 3d{sup 6}({sup 5}D)5g and 3d{sup 6}({sup 5}D)6h levels.« less

  5. BNL ATF II beamlines design

    SciTech Connect

    Fedurin, M.; Jing, Y.; Stratakis, D.

    2015-05-03

    The Brookhaven National Laboratory. Accelerator Test Facility (BNL ATF) is currently undergoing a major upgrade (ATF-II). Together with a new location and much improved facilities, the ATF will see an upgrade in its major capabilities: electron beam energy and quality and CO 2 laser power. The electron beam energy will be increased in stages, first to 100-150 MeV followed by a further increase to 500 MeV. Combined with the planned increase in CO 2 laser power (from 1-100 TW), the ATF-II will be a powerful tool for Advanced Accelerator research. A high-brightness electron beam, produced by a photocathode gun, willmore » be accelerated and optionally delivered to multiple beamlines. Besides the energy range (up to a possible 500 MeV in the final stage) the electron beam can be tailored to each experiment with options such as: small transverse beam size (<10 um), short bunch length (<100 fsec) and, combined short and small bunch options. This report gives a detailed overview of the ATFII capabilities and beamlines configuration.« less

  6. Mass spectrometry and potentiometry studies of Pb(II)-, Cd(II)- and Zn(II)-cystine complexes.

    PubMed

    Furia, Emilia; Aiello, Donatella; Di Donna, Leonardo; Mazzotti, Fabio; Tagarelli, Antonio; Thangavel, Hariprasad; Napoli, Anna; Sindona, Giovanni

    2014-01-21

    Cd(II)-, Pb(II)- and Zn(II)-cystine complexes were investigated by potentiometric and different mass spectrometric (MS) methodologies. Laser desorption mass spectrometry has provided both the composition and structure of metal-cystine complexes according to the speciation models proposed on the basis of the potentiometric data. Detection of neutral complexes was achieved by protonation or electrochemical reduction during mass spectrometric experiments. The redox activity of metal-cystine complexes was confirmed by laser desorption and charge transfer matrix assisted laser assisted MS experiments, which allowed us to observe the formation of complexes with a reduction of cystine. The stoichiometry of Cd(II)-, Pb(II)- and Zn(II)-cystine complexes was defined by observing the isotopic pattern of the investigated compound. The results suggest that interaction occurs through the carboxylate group of the ligand.

  7. Copper(II), cobalt(II) and nickel(II) complexes of lapachol: synthesis, DNA interaction, and cytotoxicity.

    PubMed

    Tabrizi, Leila; Talaie, Faranak; Chiniforoshan, Hossein

    2017-11-01

    Three novel copper(II), cobalt(II), and nickel(II) complexes of lapachol (Lap) containing 110-phenanthroline (phen) ligand, [M(Lap) 2 (phen)] (M=Cu(II), 1, Co(II), 2, and Ni(II), 3), have been synthesized and characterized using, elemental analysis and spectroscopic studies. Their interactions with calf thymus DNA (CT DNA) were investigated using viscosity, thermal denaturation, circular dichorism, fluorescence quenching, and electronic absorption spectroscopy. The DNA cleavage abilities of 1-3 have been studied, where cleavage activity of copper complex 1 is more than the complexes 2 and 3. The in vitro cytotoxic potential of the complexes 1-3 against human cervical carcinoma (HeLa), human liver hepatocellular carcinoma (HepG-2), and human colorectal adenocarcinoma (HT-29) cells indicated their promising antitumor activity with quite low IC 50 values in the range of .15-2.41 μM, which are lower than those of cisplatin.

  8. Quiet High Speed Fan II (QHSF II): Final Report

    NASA Technical Reports Server (NTRS)

    Kontos, Karen; Weir, Don; Ross, Dave

    2012-01-01

    This report details the aerodynamic, mechanical, structural design and fabrication of a Honey Engines Quiet High Speed Fan II (lower hub/tip ratio and higher specific flow than the Baseline I fan). This fan/nacelle system incorporates features such as advanced forward sweep and an advanced integrated fan/fan exit guide vane design that provides for the following characteristics: (1) Reduced noise at supersonic tip speeds, in comparison to current state-of-the-art fan technology; (2) Improved aeroelastic stability within the anticipated operating envelope; and (3) Aerodynamic performance consistent with current state-of-the-art fan technology. This fan was fabricated by Honeywell and tested in the NASA Glenn 9- by 15-Ft Low Speed Wind Tunnel for aerodynamic, aeromechanical, and acoustic performance.

  9. Synthesis, spectroscopic characterization, first order nonlinear optical properties and DFT calculations of novel Mn(II), Co(II), Ni(II), Cu(II) and Zn(II) complexes with 1,3-diphenyl-4-phenylazo-5-pyrazolone ligand

    NASA Astrophysics Data System (ADS)

    Abdel-Latif, Samir A.; Mohamed, Adel A.

    2018-02-01

    Novel Mn(II), Co(II), Ni(II), Cu(II) and Zn(II) metal ions with 1,3-diphenyl-4-phenylazo-5-pyrazolone (L) have been prepared and characterized using different analytical and spectroscopic techniques. 1:1 Complexes of Mn(II), Co(II) and Zn(II) are distorted octahedral whereas Ni(II) complex is square planar and Cu(II) is distorted trigonal bipyramid. 1:2 Complexes of Mn(II), Co(II), Cu(II) and Zn(II) are distorted trigonal bipyramid whereas Ni(II) complex is distorted tetrahedral. All complexes behave as non-ionic in dimethyl formamide (DMF). The electronic structure and nonlinear optical parameters (NLO) of the complexes were investigated theoretically at the B3LYP/GEN level of theory. Molecular stability and bond strengths have been investigated by applying natural bond orbital (NBO) analysis. The geometries of the studied complexes are non-planner. DFT calculations have been also carried out to calculate the global properties; hardness (η), global softness (S) and electronegativity (χ). The calculated small energy gap between HOMO and LUMO energies shows that the charge transfer occurs within the complexes. The total static dipole moment (μtot), the mean polarizability (<α>), the anisotropy of the polarizability (Δα) and the mean first-order hyperpolarizability (<β>) were calculated and compared with urea as a reference material. The complexes show implying optical properties.

  10. Shark class II invariant chain reveals ancient conserved relationships with cathepsins and MHC class II.

    PubMed

    Criscitiello, Michael F; Ohta, Yuko; Graham, Matthew D; Eubanks, Jeannine O; Chen, Patricia L; Flajnik, Martin F

    2012-03-01

    The invariant chain (Ii) is the critical third chain required for the MHC class II heterodimer to be properly guided through the cell, loaded with peptide, and expressed on the surface of antigen presenting cells. Here, we report the isolation of the nurse shark Ii gene, and the comparative analysis of Ii splice variants, expression, genomic organization, predicted structure, and function throughout vertebrate evolution. Alternative splicing to yield Ii with and without the putative protease-protective, thyroglobulin-like domain is as ancient as the MHC-based adaptive immune system, as our analyses in shark and lizard further show conservation of this mechanism in all vertebrate classes except bony fish. Remarkable coordinate expression of Ii and class II was found in shark tissues. Conserved Ii residues and cathepsin L orthologs suggest their long co-evolution in the antigen presentation pathway, and genomic analyses suggest 450 million years of conserved Ii exon/intron structure. Other than an extended linker preceding the thyroglobulin-like domain in cartilaginous fish, the Ii gene and protein are predicted to have largely similar physiology from shark to man. Duplicated Ii genes found only in teleosts appear to have become sub-functionalized, as one form is predicted to play the same role as that mediated by Ii mRNA alternative splicing in all other vertebrate classes. No Ii homologs or potential ancestors of any of the functional Ii domains were found in the jawless fish or lower chordates. Copyright © 2011 Elsevier Ltd. All rights reserved.

  11. Porous cellulosic adsorbent for the removal of Cd (II), Pb(II) and Cu(II) ions from aqueous media

    NASA Astrophysics Data System (ADS)

    Barsbay, Murat; Kavaklı, Pınar Akkaş; Tilki, Serhad; Kavaklı, Cengiz; Güven, Olgun

    2018-01-01

    The main objective of this work is to prepare a renewable cellulosic adsorbent by γ-initiated grafting of poly(glycidyl methacrylate) (PGMA) from cellulose substrate and subsequent modification of PGMA with chelating species, iminodiacetic acid (IDA), for Cd (II), Pb(II) and Cu(II) removal from aqueous media. Modification of PGMA grafted cellulose with IDA in aqueous solution under mild conditions has proceeded efficiently to yield a natural-based and effective porous adsorbent with well-defined properties as provided by the controlled polymerization technique, namely RAFT, applied during the radiation-induced graft copolymerization step and with sufficient degree of IDA immobilization as confirmed by XPS, FTIR, contact angle measurements and elemental analysis. In order to examine the Cd (II), Pb(II) and Cu(II) removing performance of the resulting adsorbent, batch experiments were carried out by ICP-MS. The adsorption capacities were determined as 53.4 mg Cd(II)/g polymer, 52.0 mg Pb(II)/g polymer and 69.6 mg Cu(II)/g polymer at initial feed concentration of 250 ppm, showing the promising potential of the natural-based adsorbent to steadily and efficiently chemisorb toxic metal ions.

  12. Chelation of Cu(II), Zn(II), and Fe(II) by tannin constituents of selected edible nuts.

    PubMed

    Karamać, Magdalena

    2009-12-22

    The tannin fractions isolated from hazelnuts, walnuts and almonds were characterised by colorimetric assays and by an SE-HPLC technique. The complexation of Cu(II) and Zn(II) was determined by the reaction with tetramethylmurexide, whereas for Fe(II), ferrozine was employed. The walnut tannins exhibited a significantly weaker reaction with the vanillin/HCl reagent than hazelnut and almond tannins, but the protein precipitation capacity of the walnut fraction was high. The SE-HPLC chromatogram of the tannin fraction from hazelnuts revealed the presence of oligomers with higher molecular weights compared to that of almonds. Copper ions were most effectively chelated by the constituents of the tannin fractions of hazelnuts, walnuts and almonds. At a 0.2 mg/assay addition level, the walnut tannins complexed almost 100% Cu(II). The Fe(II) complexation capacities of the tannin fractions of walnuts and hazelnuts were weaker in comparison to that of the almond tannin fraction, which at a 2.5 mg/assay addition level, bound Fe(II) by approximately 90%. The capacity to chelate Zn(II) was quite varied for the different nut tannin fractions: almond tannins bound as much as 84% Zn(II), whereas the value for walnut tannins was only 8.7%; and for hazelnut tannins, no Zn(II) chelation took place at the levels tested.

  13. Chelation of Cu(II), Zn(II), and Fe(II) by Tannin Constituents of Selected Edible Nuts

    PubMed Central

    Karamać, Magdalena

    2009-01-01

    The tannin fractions isolated from hazelnuts, walnuts and almonds were characterised by colorimetric assays and by an SE-HPLC technique. The complexation of Cu(II) and Zn(II) was determined by the reaction with tetramethylmurexide, whereas for Fe(II), ferrozine was employed. The walnut tannins exhibited a significantly weaker reaction with the vanillin/HCl reagent than hazelnut and almond tannins, but the protein precipitation capacity of the walnut fraction was high. The SE-HPLC chromatogram of the tannin fraction from hazelnuts revealed the presence of oligomers with higher molecular weights compared to that of almonds. Copper ions were most effectively chelated by the constituents of the tannin fractions of hazelnuts, walnuts and almonds. At a 0.2 mg/assay addition level, the walnut tannins complexed almost 100% Cu(II). The Fe(II) complexation capacities of the tannin fractions of walnuts and hazelnuts were weaker in comparison to that of the almond tannin fraction, which at a 2.5 mg/assay addition level, bound Fe(II) by ~90%. The capacity to chelate Zn(II) was quite varied for the different nut tannin fractions: almond tannins bound as much as 84% Zn(II), whereas the value for walnut tannins was only 8.7%; and for hazelnut tannins, no Zn(II) chelation took place at the levels tested. PMID:20054482

  14. Delta II JPSS-1 Liftoff

    NASA Image and Video Library

    2017-11-18

    A United Launch Alliance Delta II rocket lifts off from Space Launch Complex 2 at Vandenberg Air Force Base in California carrying the Joint Polar Satellite System-1, or JPSS-1, spacecraft. Built by Ball Aerospace and Technologies Corp. of Boulder, Colorado, JPSS is the first in a series four next-generation environmental satellites in a collaborative program between NOAA and NASA. JPSS-1 will gather measurements of atmospheric, terrestrial and oceanic conditions, including sea and land surface temperatures, vegetation, clouds, rainfall, snow and ice cover, fire locations, atmospheric temperature, water vapor and ozone. Liftoff was at 1:47 a.m. PST (4:47 a.m. EST), Nov. 18, 2017.

  15. ENZYMES IN CANDIDA ALBICANS II.

    PubMed Central

    Rao, G. Ramananda; Sirsi, M.; Ramakrishnan, T.

    1962-01-01

    Rao, G. Ramananda (Indian Institute of Science, Bangalore, India), M. Sirsi, and T. Ramakrishnan. Enzymes in Candida albicans. II. Tricarboxylic acid cycle and related enzymes. J. Bacteriol. 84:778–783. 1962.—Evidence is presented to show the operation of the tricarboxylic acid cycle in Candida albicans, by studies with whole cells, cell-free preparations, and by the demonstration of most of the enzymes involved in the cycle. Cell-free extracts contained the following enzymes: condensing enzyme; aconitase; isocitric, α-ketoglutaric, succinic, and malic dehydrogenases; malic enzyme; fumarase; reduced diphosphopyridine nucleotide (DPNH) oxidase; DPNH-cytochrome c reductase; reduced triphosphopyridine nucleotide (TPNH) cytochrome c reductase; and diaphorase. Pyruvic dehydrogenase, TPNH oxidase, and transhydrogenase activities could not be detected under the test conditions. PMID:13973046

  16. Optimization of simultaneous electrochemical determination of Cd(II), Pb(II), Cu(II) and Hg(II) at carbon nanotube-modified graphite electrodes.

    PubMed

    Pikna, L'ubomír; Heželová, Mária; Kováčová, Zuzana

    2015-01-01

    The health of the environment is worsening every day. Monitoring of potentially toxic elements and remediation of environmental pollution are necessary. Therefore, the research and development of simple, inexpensive, portable and effective sensors is important. Electrochemistry is a useful component of the field of environment monitoring. The present study focuses on evaluating and comparing three types of electrodes (PIGE, PIGE/MWCNT/HNO3 and PIGE/MWCNT/EDTA/HNO3) employed for the simultaneous electrochemical determination of four potentially toxic elements: Cd(II), Pb(II), Cu(II) and Hg(II). Cyclic voltammograms were measured in an acetate buffer. The LOD, LOQ, the standard and relative precisions of the method and a prediction intervals were calculated (according to the technical procedure DIN 32 645) for the three electrodes and for each measured element. The LOD for PIGE/CNT/HNO3 (the electrode with narrowest calculated prediction intervals) was 2.98 × 10(-7) mol L(-1) for Cd(II), 4.83 × 10(-7) mol L(-1) for Pb(II), 3.81 × 10(-7) mol L(-1) for Cu(II), 6.79 × 10(-7) mol L(-1) for Hg(II). One of the benefits of this study was the determination of the amount of Hg(II) in the mixture of other elements.

  17. Angiotensin II in Refractory Septic Shock.

    PubMed

    Antonucci, Elio; Gleeson, Patrick J; Annoni, Filippo; Agosta, Sara; Orlando, Sergio; Taccone, Fabio Silvio; Velissaris, Dimitrios; Scolletta, Sabino

    2017-05-01

    Refractory septic shock is defined as persistently low mean arterial blood pressure despite volume resuscitation and titrated vasopressors/inotropes in patients with a proven or suspected infection and concomitant organ dysfunction. Its management typically requires high doses of catecholamines, which can induce significant adverse effects such as ischemia and arrhythmias. Angiotensin II (Ang II), a key product of the renin-angiotensin-aldosterone system, is a vasopressor agent that could be used in conjunction with other vasopressors to stabilize critically ill patients during refractory septic shock, and reduce catecholamine requirements. However, very few clinical data are available to support Ang II administration in this setting. Here, we review the current literature on this topic to better understand the role of Ang II administration during refractory septic shock, differentiating experimental from clinical studies. We also consider the potential role of exogenous Ang II administration in specific organ dysfunction and possible pitfalls with Ang II in sepsis. Various issues remain unresolved and future studies should investigate important topics such as: the optimal dose and timing of Ang II administration, a comparison between Ang II and the other vasopressors (epinephrine; vasopressin), and Ang II effects on microcirculation.

  18. A substituted sulfonamide and its Co (II), Cu (II), and Zn (II) complexes as potential antifungal agents.

    PubMed

    Diaz, Jorge R A; Fernández Baldo, Martín; Echeverría, Gustavo; Baldoni, Héctor; Vullo, Daniela; Soria, Delia B; Supuran, Claudiu T; Camí, Gerardo E

    2016-01-01

    A sulfonamide 1-tosyl-1-H-benzo(d)imidazol-2-amine (TBZA) and three new complexes of Co(II), Cu(II), and Zn(II) have been synthesized. The compounds have been characterized by elemental analyses, FTIR, 1 H, and 13 C-NMR spectroscopy. The structure of the TBZA, and its Co(II) and Cu(II) complexes, was determined by X-ray diffraction methods. TBZA and its Co(II) complex crystallize in the triclinic P-1 space group, while the Cu(II) complex crystallizes in the monoclinic P2 1 /c space group. Antifungal activity was screened against eight pathogenic yeasts: Candida albicans (DMic 972576), Candida krusei (DMic 951705), Candida glabrata (DMic 982882), Candida tropicalis (DMic 982884), Candida dubliniensis (DMic 93695), Candida guilliermondii (DMic 021150), Cryptococcus neoformans (ATCC 24067), and Cryptococcus gattii (ATCC MYA-4561). Results on the inhibition of various human (h) CAs, hCA I, II, IV, VII, IX, and XII, and pathogenic beta and gamma CAs are also reported.

  19. Transnational Alliances: "La Clase Mágica--Nepohualtzitzin" Ethnomathematics Club

    ERIC Educational Resources Information Center

    Prieto, Linda; Claeys, Lorena; González, Everardo Lara

    2015-01-01

    This article exposes the ancient "Nepohualtzitzin" as an important contemporary mathematical tool. The design and development of "Nepohualtzitzin" Ethnomathematics Clubs (NECs) in predominantly Latina/o and low-income schools is also presented. NECs provide informal learning opportunities to develop and strengthen cultural…

  20. Kinetics of Formation of Cobalt(II)- and Nickel(II) Carbonic Anhydrase.

    ERIC Educational Resources Information Center

    McQuate, Robert S.; Reardon, John E.

    1978-01-01

    Discusses the kinetic behavior associated with the interaction of metal ions with apocarbonic anhydrase, focusing on the formation of two metallocarbonic anhydrase--the biochemically active Co(II) and the inactive Ni(II)derivatives. (GA)

  1. MHC class II expression in lung cancer.

    PubMed

    He, Yayi; Rozeboom, Leslie; Rivard, Christopher J; Ellison, Kim; Dziadziuszko, Rafal; Yu, Hui; Zhou, Caicun; Hirsch, Fred R

    2017-10-01

    Immunotherapy is an exciting development in lung cancer research. In this study we described major histocompatibility complex (MHC) Class II protein expression in lung cancer cell lines and patient tissues. We studied MHC Class II (DP, DQ, DR) (CR3/43, Abcam) protein expression in 55 non-small cell lung cancer (NSCLC) cell lines, 42 small cell lung cancer (SCLC) cell lines and 278 lung cancer patient tissues by immunohistochemistry (IHC). Seven (12.7%) NSCLC cell lines were positive for MHC Class II. No SCLC cell lines were found to be MHC Class II positive. We assessed 139 lung cancer samples available in the Hirsch Lab for MHC Class II. There was no positive MHC Class II staining on SCLC tumor cells. MHC Class II expression on TILs in SCLC was significantly lower than that on TILs in NSCLC (P<0.001). MHC Class II was also assessed in an additional 139 NSCLC tumor tissues from Medical University of Gdansk, Poland. Patients with positive staining of MHC Class II on TILs had longer regression-free survival (RFS) and overall survival (OS) than those whose TILs were MHC Class II negative (2.980 years, 95% CI 1.628-4.332 vs. 1.050 years, 95% CI 0.556-1.554, P=0.028) (3.230 years, 95% CI 2.617-3.843 vs. 1.390 years, 95% CI 0.629-2.151, P=0.014). MHC Class II was expressed both in NSCLC cell lines and tissues. However, MHC Class II was not detected in SCLC cell lines or tissue tumor cells. MHC Class II expression was lower on SCLC TILs than on NSCLC TILs. Loss of expression of MHC Class II on SCLC tumor cells and reduced expression on SCLC TILs may be a means of escaping anti-cancer immunity. Higher MHC Class II expression on TILs was correlated with better prognosis in patients with NSCLC. Copyright © 2017. Published by Elsevier B.V.

  2. Angiotensin II, corticosteroids, type II diabetes and the metabolic syndrome.

    PubMed

    Vinson, Gavin P

    2007-01-01

    Syndrome X, the Metabolic Syndrome, and type II diabetes are closely related diseases that share risk factors and symptoms, notably insulin resistance. Several factors have been proposed either to mediate the disease(s) or to be their causes, and most converge on the endocrine/paracrine functions of the adipocyte. A common feature of such systems is their relative autonomy from systemic negative feedback regulation, for example by the HPA axis. We draw particular attention to two such mechanisms, both of which are associated with, and can cause, insulin resistance: the extra-adrenal production of corticosteroids, and the tissue renin angiotensin system of the adipocyte. These show another feature: the inter-regulation of glucocorticoid action and the RAS by positive feedback. Cortisol enhances the expression of 11 beta-HSD 1, and also of angiotensinogen and angiotensin type 1 receptors. In turn, angiotensin can stimulate further corticosteroid production, from the adrenal and perhaps from extra-adrenal sources. The instability inherent in such positive loops could account for the progressive nature of the disease(s), suggesting ways to break the circle.

  3. Stress Tolerance of Photosystem II in Vivo

    PubMed Central

    Havaux, Michel

    1992-01-01

    The in vivo photochemical activity of photosystem II was inferred from modulated chlorophyll fluorescence and photoacoustic measurements in intact leaves of several plant species (Lycopersicon esculentum Mill., Solanum tuberosum L., Solanum nigrum L.) exposed to various environmental stresses (drought, heat, strong light) applied separately or in combination. Photosystem II was shown to be highly drought-resistant: even a drastic desiccation in air of detached leaf samples only marginally affected the quantum yield for photochemistry in photosystem II. However, water stress markedly modified the responses of photosystem II to superimposed constraints. The stability of photosystem II to heat was observed to increase strongly in leaves exposed to water stress conditions: heat treatments (e.g. 42°C in the dark), which caused a complete and irreversible inhibition of photosystem II in well-watered (tomato) leaves, resulted in a small and fully reversible reduction of the photochemical efficiency of photosystem II in drought-stressed leaves. In vivo photoacoustic data indicated that photosystem I was highly resistant to both heat and water stresses. When leaves were illuminated with intense white light at 25°C, photoinhibition damage of photosystem II was more pronounced in water-stressed leaves than in undesiccated controls. However, in nondehydrated leaves, photoinhibition of photosystem II was strongly temperature dependent, being drastically stimulated at high temperatures above 38 to 40°C. As a consequence, when exposed to strong light at high temperature, photosystem II photochemistry was significantly less inhibited in dehydrated leaves than in control well-hydrated leaves. Our results demonstrate the existence of a marked antagonism between physicochemical stresses, with water stress enhancing the resistance of photosystem II to constraints (heat, strong light at high temperature) that are usually associated with drought in the field. PMID:16652979

  4. FOREWORD: HELAS II International Conference

    NASA Astrophysics Data System (ADS)

    Gizon, Laurent; Roth, Markus

    2008-07-01

    Volume 118 (2008) of Journal of Physics: Conference Series provides a written record of the talks and posters presented at the HELAS II International Conference `Helioseismology, Asteroseismology and MHD Connections'. The conference was held during the week 20-24 August 2007 in Göttingen, Germany, jointly hosted by the Max Planck Institute for Solar System Research and the Faculty of Physics of the University of Göttingen. A total of 140 scientists from all over the world attended. The Scientific Organizing Committee consisted of Conny Aerts, Annie Baglin, Jørgen Christensen-Dalsgaard, Thierry Corbard, Jadwiga Daszyńska-Daszkiewicz, Stefan Dreizler, Yvonne Elsworth, Laurent Gizon (Chairman), Wolfgang Glatzel, Frank Hill, Donald Kurtz, Oskar von der Lühe, Maria Pia Di Mauro, Mário Monteiro, Pere Pallé, Markus Roth, Philip Scherrer, Manfred Schüssler, and Michael Thompson. HELAS stands for the European Helio- and Asteroseismology Network, a Coordination Action supported by the sixth Framework Programme of the European Union. It aims to bring together researchers in the fields of solar and stellar oscillations. This volume consists of 91 articles organized into sections that reflect the scientific programme of the conference: 012001-07 Wave diagnostics in physics, geophysics and astrophysics 012008-09 Perspectives on helio- and asteroseismology 012010-17 Asteroseismology: Observations 012018-25 Asteroseismology: Theory 012026-32 Global helioseismology and solar models 012033-38 Local helioseismology and magnetic activity 012039-44 Future observational projects in helio- and asteroseismology 012045-91 Poster papers. The overwhelming majority of papers discuss the seismology of the Sun and stars. Papers in the first section provide a broader perspective on wave phenomena and techniques for probing other physical systems, from living beings to the universe as a whole. We were extremely fortunate to have particularly distinguished experts to cover these topics

  5. Moderately luminous Type II supernovae

    NASA Astrophysics Data System (ADS)

    Inserra, C.; Pastorello, A.; Turatto, M.; Pumo, M. L.; Benetti, S.; Cappellaro, E.; Botticella, M. T.; Bufano, F.; Elias-Rosa, N.; Harutyunyan, A.; Taubenberger, S.; Valenti, S.; Zampieri, L.

    2013-07-01

    Context. Core-collapse Supernovae (CC-SNe) descend from progenitors more massive than about 8 M⊙. Because of the young age of the progenitors, the ejecta may eventually interact with the circumstellar medium (CSM) via highly energetic processes detectable in the radio, X-ray, ultraviolet (UV) and, sometimes, in the optical domains. Aims: In this paper we present ultraviolet, optical and near infrared observations of five Type II SNe, namely SNe 2009dd, 2007pk, 2010aj, 1995ad, and 1996W. Together with few other SNe they form a group of moderately luminous Type II events. We investigate the photometric similarities and differences among these bright objects. We also attempt to characterise them by analysing the spectral evolutions, in order to find some traces of CSM-ejecta interaction. Methods: We collected photometry and spectroscopy with several telescopes in order to construct well-sampled light curves and spectral evolutions from the photospheric to the nebular phases. Both photometry and spectroscopy indicate a degree of heterogeneity in this sample. Modelling the data of SNe 2009dd, 2010aj and 1995ad allows us to constrain the explosion parameters and the properties of the progenitor stars. Results: The light curves have luminous peak magnitudes (-16.95 < MB < -18.70). The ejected masses of 56Ni for three SNe span a wide range of values (2.8 × 10-2 M⊙ < M(56Ni)< 1.4 × 10-1 M⊙), while for a fourth (SN 2010aj) we could determine a stringent upper limit (7 × 10-3 M⊙). Clues of interaction, such as the presence of high velocity (HV) features of the Balmer lines, are visible in the photospheric spectra of SNe 2009dd and 1996W. For SN 2007pk we observe a spectral transition from a Type IIn to a standard Type II SN. Modelling the observations of SNe 2009dd, 2010aj and 1995ad with radiation hydrodynamics codes, we infer kinetic plus thermal energies of about 0.2-0.5 foe, initial radii of 2-5 × 1013 cm and ejected masses of ~5.0-9.5 M⊙. Conclusions: These

  6. 40 CFR Table II-2 to Subpart II - Collection Efficiencies of Anaerobic Processes

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 22 2013-07-01 2013-07-01 false Collection Efficiencies of Anaerobic Processes II Table II-2 to Subpart II Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Industrial Wastewater Treatment Pt. 98...

  7. 40 CFR Table II-2 to Subpart II - Collection Efficiencies of Anaerobic Processes

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 21 2014-07-01 2014-07-01 false Collection Efficiencies of Anaerobic Processes II Table II-2 to Subpart II Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Industrial Wastewater Treatment Pt. 98...

  8. Diet History Questionnaire II & Canadian Diet History Questionnaire II: Web-based DHQ

    Cancer.gov

    The Web-based versions of DHQ II and C-DHQ II are identical in content to the paper forms. By automating the DHQ II and providing versions on the Web for public use, researchers have another tool to collect and analyze food frequency questionnaire data.

  9. Preschool Racial Attitude Measure II (PRAM II): Technical Report #1: 1970-71 Standardization Study.

    ERIC Educational Resources Information Center

    Williams, John E.

    This report provides detailed technical information concerning the Preschool Racial Attitude Measure II (PRAM II) a method for assessing the attitudes of pre-literate children toward light- and dark-skinned individuals. Several major changes were involved in the PRAM II revision: (1) the length was doubled, (2) the general artistic quality of the…

  10. Spectral and thermodynamic properties of Ag(I), Au(III), Cd(II), Co(II), Fe(III), Hg(II), Mn(II), Ni(II), Pb(II), U(IV), and Zn(II) binding by methanobactin from Methylosinus trichosporium OB3b.

    PubMed

    Choi, Dong W; Do, Young S; Zea, Corbin J; McEllistrem, Marcus T; Lee, Sung-W; Semrau, Jeremy D; Pohl, Nicola L; Kisting, Clint J; Scardino, Lori L; Hartsel, Scott C; Boyd, Eric S; Geesey, Gill G; Riedel, Theran P; Shafe, Peter H; Kranski, Kim A; Tritsch, John R; Antholine, William E; DiSpirito, Alan A

    2006-12-01

    Methanobactin (mb) is a novel chromopeptide that appears to function as the extracellular component of a copper acquisition system in methanotrophic bacteria. To examine this potential physiological role, and to distinguish it from iron binding siderophores, the spectral (UV-visible absorption, circular dichroism, fluorescence, and X-ray photoelectron) and thermodynamic properties of metal binding by mb were examined. In the absence of Cu(II) or Cu(I), mb will bind Ag(I), Au(III), Co(II), Cd(II), Fe(III), Hg(II), Mn(II), Ni(II), Pb(II), U(VI), or Zn(II), but not Ba(II), Ca(II), La(II), Mg(II), and Sr(II). The results suggest metals such as Ag(I), Au(III), Hg(II), Pb(II) and possibly U(VI) are bound by a mechanism similar to Cu, whereas the coordination of Co(II), Cd(II), Fe(III), Mn(II), Ni(II) and Zn(II) by mb differs from Cu(II). Consistent with its role as a copper-binding compound or chalkophore, the binding constants of all the metals examined were less than those observed with Cu(II) and copper displaced other metals except Ag(I) and Au(III) bound to mb. However, the binding of different metals by mb suggests that methanotrophic activity also may play a role in either the solubilization or immobilization of many metals in situ.

  11. Mastracchio works with BASS-II

    NASA Image and Video Library

    2014-02-18

    ISS038-E-053251 (18 Feb. 2014) --- NASA astronaut Rick Mastracchio, Expedition 38 flight engineer, works with the Burning and Suppression of Solids (BASS-II) experiment in the Microgravity Science Glovebox (MSG) located in the Destiny laboratory of the International Space Station. BASS-II explores how different substances burn in microgravity with benefits for combustion on Earth and fire safety in space.

  12. Biology II Curriculum Guide. Bulletin 1820.

    ERIC Educational Resources Information Center

    Louisiana State Dept. of Education, Baton Rouge. Div. of Academic Programs.

    In 1986, the Louisiana State Board of Elementary and Secondary Education requested that an advanced course in Biology II be developed. The resulting curriculum guide contains grade appropriate goals, skills, and competencies; suggested activities; suggested materials of instruction; and minimum time allotments for instruction. Biology II is a…

  13. Mastracchio works with BASS-II

    NASA Image and Video Library

    2014-02-18

    ISS038-E-053250 (18 Feb. 2014) --- NASA astronaut Rick Mastracchio, Expedition 38 flight engineer, works with the Burning and Suppression of Solids (BASS-II) experiment in the Microgravity Science Glovebox (MSG) located in the Destiny laboratory of the International Space Station. BASS-II explores how different substances burn in microgravity with benefits for combustion on Earth and fire safety in space.

  14. Addressing Instructional Avoidance with Tier II Supports

    ERIC Educational Resources Information Center

    Anderson, Cynthia M.; Turtura, Jessica; Parry, Michael

    2013-01-01

    In a 3-tiered, prevention-oriented framework, Tier II (secondary, targeted) interventions are designed for students whose problem behaviors have not responded to Tier I but are not severe enough to warrant an individualized Tier III intervention. Tier II interventions are implemented similarly across students receiving the intervention and can be…

  15. A new subclass of Type II supernovae?

    NASA Technical Reports Server (NTRS)

    Schlegel, Eric M.

    1990-01-01

    Observations of Type II supernovae are reported, focusing on evidence supporting the need for a new SN subclass. The objects that are likely to consistute the new subclass are listed and the properties that separate these objects from the mass of SN II objects are described.

  16. Children Teaching Children II. [CD-ROM].

    ERIC Educational Resources Information Center

    California State Dept. of Education, Sacramento. Office of School Improvement.

    Children Teaching Children (CTC): Collection II is a CD-ROM created at 6 elementary schools in the West Contra Costa Unified School District (California) as part of the Coaching Odyssey for school improvement. CTC II, published by the California Department of Education, is an effective early literacy intervention that integrates the development of…

  17. Punctate lenticular opacities in type II mannosidosis.

    PubMed

    Letson, R D; Desnick, R J

    1978-02-01

    Ocular examination in four siblings with Type II mannosidosis revealed scattered punctate opacities in the entire lens. No such lenticular opacities were described in 28 previously reported patients, 17 presumed Type II and 11 Type I. Complete ocular examination with particular attention to opacities in the lens and cornea may provide additional phenotypic data for identification of genetic variants with amnnosidosis.

  18. Inhibition of topoisomerase II by liriodenine.

    PubMed

    Woo, S H; Reynolds, M C; Sun, N J; Cassady, J M; Snapka, R M

    1997-08-15

    The cytotoxic oxoaporphine alkaloid liriodenine, isolated from Cananga odorata, was found to be a potent inhibitor of topoisomerase II (EC 5.99.1.3) both in vivo and in vitro. Liriodenine treatment of SV40 (simian virus 40)-infected CV-1 cells caused highly catenated SV40 daughter chromosomes, a signature of topoisomerase II inhibition. Strong catalytic inhibition of topoisomerase II by liriodenine was confirmed by in vitro assays with purified human topoisomerase II and kinetoplast DNA. Liriodenine also caused low-level protein-DNA cross-links to pulse-labeled SV40 chromosomes in vivo, suggesting that it may be a weak topoisomerase II poison. This was supported by the finding that liriodenine caused topoisomerase II-DNA cross-links in an in vitro assay for topoisomerase II poisons. Verapamil did not increase either liriodenine-induced protein-DNA cross-links or catalytic inhibition of topoisomerase II in SV40-infected cells. This indicates that liriodenine is not a substrate for the verapamil-sensitive drug efflux pump in CV-1 cells.

  19. World War II Homefront: A Historiography.

    ERIC Educational Resources Information Center

    Winkler, Allan M.

    2002-01-01

    Highlights the scholarship that exists on the World War II homefront covering topics such as World War II as a good war, Franklin D. Roosevelt, economic policy, propaganda, status of women and women's employment, the role of African Americans, racial violence, and the Japanese American experience. (CMK)

  20. World War II: A Technology Lesson Plan.

    ERIC Educational Resources Information Center

    Hagar, Suzy

    1990-01-01

    Presents a class activity on the history, causes, and consequences of World War II. Focuses on the development and deployment of the atomic bomb. Utilizes a Video Encyclopedia Program for historical background. Divides the class into groups that are responsible for researching and preparing a videotape on a World War II topic. (RW)

  1. World War II Memorial Learning Activities.

    ERIC Educational Resources Information Center

    Tennessee State Dept. of Education, Nashville.

    These learning activities can help students get the most out of a visit to the Tennessee World War II Memorial, a group of ten pylons located in Nashville (Tennessee). Each pylon contains informational text about the events of World War II. The ten pylons are listed as: (1) "Pylon E-1--Terror: America Enters the War against Fascism, June…

  2. Hearing Restoration in Neurofibromatosis Type II Patients

    PubMed Central

    Lee, Jeon Mi; Chang, Jin Woo; Choi, Jae Young

    2016-01-01

    Patients with neurofibromatosis type II will eventually succumb to bilateral deafness. For patients with hearing loss, modern medical science technology can provide efficient hearing restoration through a number of various methods. In this article, several hearing restoration methods for patients with neurofibromatosis type II are introduced. PMID:27189272

  3. HTLV-II infection in Florida Indians.

    PubMed

    Levine, P H; Jacobson, S; Elliott, R; Cavallero, A; Colclough, G; Dorry, C; Stephenson, C; Knigge, R M; Drummond, J; Nishimura, M

    1993-02-01

    A significantly increased prevalence of antibodies to human T-cell leukemia virus (HTLV) has been described in several native American populations in the United States and Latin America. Initial virologic studies indicate that HTLV-II is the predominant virus responsible for this antibody pattern. We obtained blood samples from 106 Seminole Indians living on four reservations in Southern Florida. Seropositivity to HTLV-I/II was found in 14 (13.2%) of these individuals. Polymerase chain reaction (PCR) documented HTLV-II and the absence of HTLV-I in 7 of the 9 donors available for follow-up testing of white blood cells. Evaluation of various risk factors excluded blood transfusion or intravenous drug use as an important contributing factor to the HTLV-II seroprevalence rate. These studies support the hypothesis that HTLV-II is endemic in many native American tribes in the Western hemisphere.

  4. Visual Fixation in Chiari Type II Malformation

    PubMed Central

    Salman, Michael S.; Sharpe, James A.; Lillakas, Linda; Dennis, Maureen; Steinbach, Martin J.

    2011-01-01

    Chiari type II malformation is a congenital deformity of the hindbrain. Square wave jerks are horizontal involuntary saccades that interrupt fixation. Cerebellar disorders may be associated with frequent square wave jerks or saccadic oscillations such as ocular flutter. The effects of Chiari type II malformation on visual fixation are unknown. We recorded eye movements using an eye tracker in 21 participants with Chiari type II malformation, aged 8 to 19 years while they fixated a target for 1 minute. Thirty-eight age-matched healthy participants served as controls. Square wave jerks’ parameters were similar in the 2 groups. Saccadic oscillations were not seen. Chiari type II malformation is not associated with pathological square wave jerks or abnormal saccadic oscillations. The congenital nature of this deformity may permit compensation that preserves stable visual fixation. Alternatively, the deformity of Chiari type II malformation may spare parts of the cerebellum that usually cause fixation instability when damaged. PMID:19182152

  5. Special Issue International CAWSES-II Symposium

    NASA Technical Reports Server (NTRS)

    Yamamoto, Mamoru; Shiokawa, Kazuo; Nakamura, Takuji; Gopalswamy, Nat

    2016-01-01

    This special issue gathered papers from the International CAWSES-II Symposium (November 18-22, 2013 at Nagoya University, Japan). Climate and Weather of the Sun-Earth System II (CAWSES-II) is an international scientific program sponsored by Scientific Committee on Solar-Terrestrial Physics (SCOSTEP) that continued from 2009 to 2013. The program was established with the aim of significantly enhancing our understanding of the space environment and its impacts on life and society. The International CAWSES-II Symposium was successful with 388 presentations; and from that, 38 papers were published in this special issue. In this preface, we briefly discuss the contents of the special issue as well as the CAWSES-II review papers published in Progress in Earth and Planetary Science (PEPS) in 2014-2015.

  6. Special issue "International CAWSES-II Symposium"

    NASA Astrophysics Data System (ADS)

    Yamamoto, Mamoru; Shiokawa, Kazuo; Nakamura, Takuji; Gopalswamy, Nat

    2016-02-01

    This special issue gathered papers from the International CAWSES-II Symposium (November 18-22, 2013 at Nagoya University, Japan). Climate and Weather of the Sun-Earth System II (CAWSES-II) is an international scientific program sponsored by Scientific Committee on Solar-Terrestrial Physics (SCOSTEP) that continued from 2009 to 2013. The program was established with the aim of significantly enhancing our understanding of the space environment and its impacts on life and society. The International CAWSES-II Symposium was successful with 388 presentations; and from that, 38 papers were published in this special issue. In this preface, we briefly discuss the contents of the special issue as well as the CAWSES-II review papers published in Progress in Earth and Planetary Science (PEPS) in 2014-2015.

  7. Reoperative Cardiac Surgery - Part II.

    PubMed

    Tribble, Curtis G

    2018-04-10

    The preparation for a reoperative cardiac surgical case was covered in Part I of this two part review [Tribble 2018]. Part II will cover primarily intraoperative strategies and techniques.  As noted in Part I, there has been surprisingly little written about the strategies and techniques of reoperative cardiac surgery. Thus, the goal of this two-part review is to collect and collate some of the lessons, abjurations, and tenets related to reoperative cardiac surgery that may be valuable to cardiac surgeons, especially those in training or early in their careers.Some time-honored admonitions that can apply to all complex operations, often enunciated by "old salts," bear repeating:•  Everything matters. Nothing is neutral.•  Some say that a "life or death" decision is made, on average, every 10 seconds during cardiac surgery. •  If something can go wrong, presume that it will.•  If it seems absolutely impossible for something to go wrong, it will anyway, at least some of the time.•  When something does go wrong, it generally does so all at once.•  If what you are doing is working, keep on doing it. If it ain't working, do something else.

  8. Multi-metals column adsorption of lead(II), cadmium(II) and manganese(II) onto natural bentonite clay.

    PubMed

    Alexander, Jock Asanja; Surajudeen, Abdulsalam; Aliyu, El-Nafaty Usman; Omeiza, Aroke Umar; Zaini, Muhammad Abbas Ahmad

    2017-10-01

    The present work was aimed at evaluating the multi-metals column adsorption of lead(II), cadmium(II) and manganese(II) ions onto natural bentonite. The bentonite clay adsorbent was characterized for physical and chemical properties using X-ray diffraction, X-ray fluorescence, Brunauer-Emmett-Teller surface area and cation exchange capacity. The column performance was evaluated using adsorbent bed height of 5.0 cm, with varying influent concentrations (10 mg/L and 50 mg/L) and flow rates (1.4 mL/min and 2.4 mL/min). The result shows that the breakthrough time for all metal ions ranged from 50 to 480 minutes. The maximum adsorption capacity was obtained at initial concentration of 10 mg/L and flow rate of 1.4 mL/min, with 2.22 mg/g of lead(II), 1.71 mg/g of cadmium(II) and 0.37 mg/g of manganese(II). The order of metal ions removal by natural bentonite is lead(II) > cadmium(II) > manganese(II). The sorption performance and the dynamic behaviour of the column were predicted using Adams-Bohart, Thomas, and Yoon-Nelson models. The linear regression analysis demonstrated that the Thomas and Yoon-Nelson models fitted well with the column adsorption data for all metal ions. The natural bentonite was effective for the treatment of wastewater laden with multi-metals, and the process parameters obtained from this work can be used at the industrial scale.

  9. Zinc(II) and copper(II) complexes of beta-substituted hydroxylporphyrins as tumor photosensitizers.

    PubMed

    Huang, Qimao; Pan, Zhiquan; Wang, Ping; Chen, Zhangping; Zhang, Xiaolian; Xu, Hansheng

    2006-06-01

    Novel photosensitizers beta-(hydroquinon-2-yl)-5,10,15,20-tetra(4-hydroxylphenyl)porphyrinato zinc(II) (Zn(II)P) and beta-(hydroquinon-2-yl)-5,10,15,20-tetra(4-hydroxylphenyl)porphyrinato copper(II) (Cu(II)P) were synthesized and characterized. Their ability of producing singlet oxygen under irradiation was detected by the measurement of decomposition of 1,3-diphenylisobenzofuran (DPBF). The preliminary biological activity studies show that the Zn(II)P has photo-toxicity on human chronic myelogenous leukemia cell (K562) and could cleave supercoiled DNA (pBR 322 DNA), while the Cu(II)P has inferior biological activity. Results showed Zn(II)P having high anti-tumor activity, which presents a promising photosensitizer for photodynamic therapy.

  10. Chitosan film loaded with silver nanoparticles-sorbent for solid phase extraction of Al(III), Cd(II), Cu(II), Co(II), Fe(III), Ni(II), Pb(II) and Zn(II).

    PubMed

    Djerahov, Lubomir; Vasileva, Penka; Karadjova, Irina; Kurakalva, Rama Mohan; Aradhi, Keshav Krishna

    2016-08-20

    The present study describes the ecofriendly method for the preparation of chitosan film loaded with silver nanoparticles (CS-AgNPs) and application of this film as efficient sorbent for separation and enrichment of Al(III), Cd(II), Cu(II), Co(II), Fe(III), Ni(II), Pb(II) and Zn(II). The stable CS-AgNPs colloid was prepared by dispersing the AgNPs sol in chitosan solution at appropriate ratio and further used to obtain a cast film with very good stability under storage and good mechanical strength for easy handling in aqueous medium. The incorporation of AgNPs in the structure of CS film and interaction between the polymer matrix and nanoparticles were confirmed by UV-vis and FTIR spectroscopy. The homogeneously embedded AgNPs (average diameter 29nm, TEM analysis) were clearly observed throughout the film by SEM. The CS-AgNPs nanocomposite film shows high sorption activity toward trace metals under optimized chemical conditions. The results suggest that the CS-AgNPs nanocomposite film can be feasibly used as a novel sorbent material for solid-phase extraction of metal pollutants from surface waters. Copyright © 2016 Elsevier Ltd. All rights reserved.

  11. [O II] nebular emission from Mg II absorbers: star formation associated with the absorbing gas

    NASA Astrophysics Data System (ADS)

    Joshi, Ravi; Srianand, Raghunathan; Petitjean, Patrick; Noterdaeme, Pasquier

    2017-10-01

    We present nebular emission associated with 198 strong Mg II absorbers at 0.35 ≤z ≤ 1.1 in the fibre spectra of quasars from the Sloan Digital Sky Survey. Measured [O II] luminosities (L_[O II]) are typical of sub-L⋆ galaxies with derived star formation rate (uncorrected for fibre losses and dust reddening) in the range of 0.5-20 M⊙ yr-1. Typically less than ∼3 per cent of the Mg II systems with rest equivalent width, W2796≥2Å, show L_[O II] ≥0.3 L^{\\star }_[O II]. The detection rate is found to increase with increasing W2796 and z. No significant correlation is found between W2796 and L_[O II] even when we restrict the samples to narrow z ranges. A strong correlation is seen between L_[O II] and z. While this is expected from the luminosity evolution of galaxies, we show that finite fibre size plays a very crucial role in this correlation. The measured nebular line ratios (like [O III]/[O II] and [O III]/H β) and their z evolution are consistent with those of galaxies detected in deep surveys. Based on the median stacked spectra, we infer the average metallicity (log Z ∼8.3), ionization parameter (log q∼7.5) and stellar mass (log (M/M⊙) ∼ 9.3). The Mg II systems with nebular emission typically have W2796 ≥2 Å, Mg II doublet ratio close to 1 and W(Fe II λ2600)/W2796∼0.5 as often seen in damped Ly α and 21-cm absorbers at these redshifts. This is the biggest reported sample of [O II] emission from Mg II absorbers at low-impact parameters ideally suited for probing various feedback processes at play in z ≤ 1 galaxies.

  12. New Rh 2 (II,II) Architecture for the Catalytic Reduction of H +

    DOE PAGES

    White, Travis A.; Witt, Suzanne E.; Li, Zhanyong; ...

    2015-09-25

    Formamidinate-bridged Rh 2 II,II complexes containing diimine ligands of the formula cis-[Rh 2 II,II(μ-DTolF) 2(NN) 2] 2+ (Rh 2-NN 2), where DTolF = p-ditolylformamidinate and NN = dppn (benzo[i]dipyrido[3,2-a:2',3'-h]quinoxaline), dppz (dipyrido[3,2-a:2',3'-c]phenazine), and phen (1,10-phenanthroline), electrocatalytically reduce H + to H 2 in DMF solutions containing CH 3COOH at a glassy carbon electrode. Cathodic scans in the absence of acid display a Rh III,II/II,II reduction at -0.90 V vs Fc +/Fc followed by NN 0/– reduction at -1.13, -1.36, and -1.65 V for Rh 2-dppn 2, Rh 2-dppz 2, and Rh 2-phen 2, respectively. Upon the addition of acid, Rh 2-dppnmore » 2 and Rh 2-dppz 2 undergo reduction–protonation–reduction at each pyrazine-containing NN ligand prior to the Rh 2 II,II/II,I reduction. The Rh 2 II,I species is thus protonated at one of the metal centers, resulting in the formation of the corresponding Rh 2 II,III-hydride. In the case of Rh 2-phen 2, the reduction of the phen ligand is followed by intramolecular electron transfer to the Rh 2 II,II core in the presence of protons to form a Rh 2 II,III-hydride species. Further reduction and protonation at the Rh 2 core for all three complexes rapidly catalyzes H 2 formation with varied calculated turnover frequencies (TOF) and overpotential values (η): 2.6 × 10 4 s –1 and 0.56 V for Rh 2-dppn, 2.8 × 10 4 s –1 and 0.50 V for Rh 2-dppz 2, and 5.9 × 10 4 s –1 and 0.64 V for Rh 2-phen 2. Bulk electrolysis confirmed H 2 formation, and further CH 3COOH addition regenerates H 2 production, attesting to the robust nature of the architecture. The cis-[Rh 2 II,II(μ-DTolF) 2(NN) 2] 2+ architecture benefits by combining electron-rich formamidinate bridges, a redox-active Rh 2 II,II core, and electron-accepting NN diimine ligands to allow for the electrocatalysis of H + substrate to H 2 fuel.« less

  13. New Rh 2 (II,II) Architecture for the Catalytic Reduction of H +

    SciTech Connect

    White, Travis A.; Witt, Suzanne E.; Li, Zhanyong

    2015-09-25

    Formamidinate-bridged Rh 2 II,II complexes containing diimine ligands of the formula cis-[Rh 2 II,II(μ-DTolF) 2(NN) 2] 2+ (Rh 2-NN 2), where DTolF = p-ditolylformamidinate and NN = dppn (benzo[i]dipyrido[3,2-a:2′,3′-h]quinoxaline), dppz (dipyrido[3,2-a:2′,3′-c]phenazine), and phen (1,10-phenanthroline), electrocatalytically reduce H + to H 2 in DMF solutions containing CH 3COOH at a glassy carbon electrode. Cathodic scans in the absence of acid display a Rh III,II/II,II reduction at −0.90 V vs Fc +/Fc followed by NN 0/– reduction at −1.13, −1.36, and −1.65 V for Rh 2-dppn 2, Rh 2-dppz 2, and Rh 2-phen 2, respectively. Upon the addition of acid, Rh 2-dppnmore » 2 and Rh 2-dppz 2 undergo reduction–protonation–reduction at each pyrazine-containing NN ligand prior to the Rh 2 II,II/II,I reduction. The Rh 2 II,I species is thus protonated at one of the metal centers, resulting in the formation of the corresponding Rh 2 II,III-hydride. In the case of Rh 2-phen 2, the reduction of the phen ligand is followed by intramolecular electron transfer to the Rh 2 II,II core in the presence of protons to form a Rh 2 II,III-hydride species. Further reduction and protonation at the Rh 2 core for all three complexes rapidly catalyzes H 2 formation with varied calculated turnover frequencies (TOF) and overpotential values (η): 2.6 × 10 4 s –1 and 0.56 V for Rh 2-dppn, 2.8 × 10 4 s –1 and 0.50 V for Rh 2-dppz 2, and 5.9 × 10 4 s –1 and 0.64 V for Rh 2-phen 2. Bulk electrolysis confirmed H 2 formation, and further CH 3COOH addition regenerates H 2 production, attesting to the robust nature of the architecture. The cis-[Rh 2 II,II(μ-DTolF) 2(NN) 2] 2+ architecture benefits by combining electron-rich formamidinate bridges, a redox-active Rh 2 II,II core, and electron-accepting NN diimine ligands to allow for the electrocatalysis of H + substrate to H 2 fuel.« less

  14. TFOS DEWS II pathophysiology report.

    PubMed

    Bron, Anthony J; de Paiva, Cintia S; Chauhan, Sunil K; Bonini, Stefano; Gabison, Eric E; Jain, Sandeep; Knop, Erich; Markoulli, Maria; Ogawa, Yoko; Perez, Victor; Uchino, Yuichi; Yokoi, Norihiko; Zoukhri, Driss; Sullivan, David A

    2017-07-01

    The TFOS DEWS II Pathophysiology Subcommittee reviewed the mechanisms involved in the initiation and perpetuation of dry eye disease. Its central mechanism is evaporative water loss leading to hyperosmolar tissue damage. Research in human disease and in animal models has shown that this, either directly or by inducing inflammation, causes a loss of both epithelial and goblet cells. The consequent decrease in surface wettability leads to early tear film breakup and amplifies hyperosmolarity via a Vicious Circle. Pain in dry eye is caused by tear hyperosmolarity, loss of lubrication, inflammatory mediators and neurosensory factors, while visual symptoms arise from tear and ocular surface irregularity. Increased friction targets damage to the lids and ocular surface, resulting in characteristic punctate epithelial keratitis, superior limbic keratoconjunctivitis, filamentary keratitis, lid parallel conjunctival folds, and lid wiper epitheliopathy. Hybrid dry eye disease, with features of both aqueous deficiency and increased evaporation, is common and efforts should be made to determine the relative contribution of each form to the total picture. To this end, practical methods are needed to measure tear evaporation in the clinic, and similarly, methods are needed to measure osmolarity at the tissue level across the ocular surface, to better determine the severity of dry eye. Areas for future research include the role of genetic mechanisms in non-Sjögren syndrome dry eye, the targeting of the terminal duct in meibomian gland disease and the influence of gaze dynamics and the closed eye state on tear stability and ocular surface inflammation. Copyright © 2017 Elsevier Inc. All rights reserved.

  15. Carotenoid oxidation in photosystem II.

    PubMed

    Hanley, J; Deligiannakis, Y; Pascal, A; Faller, P; Rutherford, A W

    1999-06-29

    The oxidation of carotenoid upon illumination at low temperature has been studied in Mn-depleted photosystem II (PSII) using EPR and electronic absorption spectroscopy. Illumination of PSII at 20 K results in carotenoid cation radical (Car+*) formation in essentially all of the centers. When a sample which was preilluminated at 20 K was warmed in darkness to 120 K, Car+* was replaced by a chlorophyll cation radical. This suggests that carotenoid functions as an electron carrier between P680, the photooxidizable chlorophyll in PSII, and ChlZ, the monomeric chlorophyll which acts as a secondary electron donor under some conditions. By correlating with the absorption spectra at different temperatures, specific EPR signals from Car+* and ChlZ+* are distinguished in terms of their g-values and widths. When cytochrome b559 (Cyt b559) is prereduced, illumination at 20 K results in the oxidation of Cyt b559 without the prior formation of a stable Car+*. Although these results can be reconciled with a linear pathway, they are more straightforwardly explained in terms of a branched electron-transfer pathway, where Car is a direct electron donor to P680(+), while Cyt b559 and ChlZ are both capable of donating electrons to Car+*, and where the ChlZ donates electrons when Cyt b559 is oxidized prior to illumination. These results have significant repercussions on the current thinking concerning the protective role of the Cyt b559/ChlZ electron-transfer pathways and on structural models of PSII.

  16. Central Arterial Aging and Angiotensin II Signaling.

    PubMed

    Wang, Mingyi; Khazan, Benjamin; Lakatta, Edward G

    2010-11-01

    Arterial remodeling over time is a cornerstone of normal systemic aging. The age-associated arterial structural and functional changes in the intima, the media, and the adventitia are closely linked to angiotensin II (Ang II) signaling. A growing line of evidence indicates that essential elements of Ang II signaling, which encompasses milk fat globule epidermal growth factor-8, calpain-1, transforming growth factor-β1, matrix metalloproteinase-2/9, monocyte chemoattractant protein-1, nicotinamide adenine dinucleotide phosphate-oxidase, and reactive oxygen species, are upregulated within the central arterial wall in rats, nonhuman primates, and humans during aging. In vitro studies show that the elevation of Ang II signaling induces the accumulation of collagen and advanced glycated end-products, the degradation of elastin, and the increased cell cycle disorder, invasion, and hypertrophy of endothelial and vascular smooth muscle cells. Further, in vivo studies demonstrate that increased Ang II signaling accelerates arterial aging. Conversely, attenuating Ang II signaling via an inhibition of angiotensin conversing enzyme or a blockade of AT1 activation retards age-associated arterial remodeling. This review attempts to integrate complex facts of Ang II signaling within the aged central arterial wall and may shed light on new therapeutic targets for arterial aging.

  17. Oxidation of Fe(II) in rainwater.

    PubMed

    Willey, J D; Whitehead, R F; Kieber, R J; Hardison, D R

    2005-04-15

    Photochemically produced Fe(II) is oxidized within hours under environmentally realistic conditions in rainwater. The diurnal variation between photochemical production and reoxidation of Fe(II) observed in our laboratory accurately mimics the behavior of ferrous iron observed in field studies where the highest concentrations of dissolved Fe(ll) occur in afternoon rain during the period of maximum sunlight intensity followed by gradually decreasing concentrations eventually returning to early morning pre-light values. The experimental work presented here, along with the results of kinetics studies done by others, suggests thatthe primary process responsible for the decline in photochemically produced Fe(II) concentrations is oxidation by hydrogen peroxide. This reaction is first order with respect to both the concentrations of Fe(II) and H2O2. The second-order rate constant determined for six different authentic rain samples varied over an order of magnitude and was always less than or equal to the rate constant determined for this reaction in simple acidic solutions. Oxidation of photochemically produced ferrous iron by other oxidants including molecular oxygen, ozone, hydroxyl radical, hydroperoxyl/superoxide radical, and hexavalent chromium were found to be insignificant under the conditions present in rainwater. This study shows that Fe(II) occurs as at least two different chemical species in rain; photochemically produced Fe(II) that is oxidized over time periods of hours, and a background Fe(II) that is protected against oxidation, perhaps by organic complexation, and is stable against oxidation for days. Because the rate of oxidation of photochemically produced Fe(II) does not increase with increasing rainwater pH, the speciation of this more labile form of Fe(II) is also not controlled by simple hydrolysis reactions.

  18. CAPPS II: the foundation of aviation security?

    PubMed

    Barnett, Arnold

    2004-08-01

    A new computer system is being developed to classify U.S. air travelers by the degree of terrorist threat they might pose. Reports indicate that the system--called CAPPS II--would use large amounts of information about each passenger, perhaps including such personal details as his or her magazine-subscription behavior. We argue that what is publicly known about CAPPS II raises questions about how substantially the system would improve aviation security. We discuss conditions under which CAPPS II could yield safety benefits, but suggest that it might be more prudent to view the system as one component of future security arrangements rather than the centerpiece of these arrangements.

  19. Delta II Second stage lift and mate

    NASA Image and Video Library

    2007-01-19

    On Pad 17-B at Cape Canaveral Air Force Station, the Delta II second stage is being lowered toward the Delta II first stage, already in place inside the mobile service tower. The Delta II is the launch vehicle for the THEMIS spacecraft. THEMIS consists of five identical probes, the largest number of scientific satellites ever launched into orbit aboard a single rocket. This unique constellation of satellites will resolve the tantalizing mystery of what causes the spectacular sudden brightening of the aurora borealis and aurora australis - the fiery skies over the Earth's northern and southern polar regions. THEMIS is scheduled to launch Feb. 15 from Cape Canaveral Air Force Station.

  20. Synthesis, characterization and anti-microbial evaluation of Cu(II), Ni(II), Pt(II) and Pd(II) sulfonylhydrazone complexes; 2D-QSAR analysis of Ni(II) complexes of sulfonylhydrazone derivatives

    NASA Astrophysics Data System (ADS)

    Özbek, Neslihan; Alyar, Saliha; Alyar, Hamit; Şahin, Ertan; Karacan, Nurcan

    2013-05-01

    Copper(II), nickel(II), platinum(II) and palladium(II) complexes with 2-hydroxy-1-naphthaldehyde-N-methylpropanesulfonylhydrazone (nafpsmh) derived from propanesulfonic acid-1-methylhydrazide (psmh) were synthesized, their structure were identified, and antimicrobial activity of the compounds was screened against three Gram-positive and three Gram-negative bacteria. The results of antimicrobial studies indicate that Pt(II) and Pd(II) complexes showed the most activity against all bacteria. The crystal structure of 2-hydroxy-1-naphthaldehyde-N-methylpropanesulfonylhydrazone (nafpsmh) was also investigated by X-ray analysis. A series of Ni(II) sulfonyl hydrazone complexes (1-33) was synthesized and tested in vitro against Escherichia coli and Staphylococcus aureus. Their antimicrobial activities were used in the QSAR analysis. Four-parameter QSAR models revealed that nucleophilic reaction index for Ni and O atoms, and HOMO-LUMO energy gap play key roles in the antimicrobial activity.

  1. Genetics Home Reference: distal hereditary motor neuropathy, type II

    MedlinePlus

    ... hereditary motor neuropathy, type II Distal hereditary motor neuropathy, type II Printable PDF Open All Close All ... the expand/collapse boxes. Description Distal hereditary motor neuropathy, type II is a progressive disorder that affects ...

  2. Removal of dissolved copper(II) and zinc(II) by aerobic granular sludge.

    PubMed

    Xu, H; Tay, J H; Foo, S K; Yang, S F; Liu, Y

    2004-01-01

    This study investigated the adsorption kinetics of dissolved copper(II) and zinc(II) by aerobic granular sludge. Two series of batch experiments were conducted at different initial copper(II), zinc(II) concentrations (Co) and initial granule concentrations (Xo). Results showed that the biosorption kinetics of individual copper(II) and zinc(II) by aerobic granules were closely related to Co and Xo. The maximum biosorption capacity of individual copper(II) and zinc(II) by aerobic granules was 246.1 mg g(-1) and 180 mg g(-1), respectively. In order to theoretically interpret the results obtained, two kinetic models previously developed for biosorption were employed and compared in this study. It was found that the model proposed by Liu et al. (2003) could fit the experimental data very well, but the second-order model failed to fit the data in some cases. It appears that aerobic granules would be potential biosorbent with high efficiency for the removal of dissolved copper(II) and zinc(II) from wastewater.

  3. Kinetics of homogeneous and surface-catalyzed mercury(II) reduction by iron(II)

    USGS Publications Warehouse

    Amirbahman, Aria; Kent, Douglas B.; Curtis, Gary P.; Marvin-DiPasquale, Mark C.

    2013-01-01

    Production of elemental mercury, Hg(0), via Hg(II) reduction is an important pathway that should be considered when studying Hg fate in environment. We conducted a kinetic study of abiotic homogeneous and surface-catalyzed Hg(0) production by Fe(II) under dark anoxic conditions. Hg(0) production rate, from initial 50 pM Hg(II) concentration, increased with increasing pH (5.5–8.1) and aqueous Fe(II) concentration (0.1–1 mM). The homogeneous rate was best described by the expression, rhom = khom [FeOH+] [Hg(OH)2]; khom = 7.19 × 10+3 L (mol min)−1. Compared to the homogeneous case, goethite (α-FeOOH) and hematite (α-Fe2O3) increased and γ-alumina (γ-Al2O3) decreased the Hg(0) production rate. Heterogeneous Hg(0) production rates were well described by a model incorporating equilibrium Fe(II) adsorption, rate-limited Hg(II) reduction by dissolved and adsorbed Fe(II), and rate-limited Hg(II) adsorption. Equilibrium Fe(II) adsorption was described using a surface complexation model calibrated with previously published experimental data. The Hg(0) production rate was well described by the expression rhet = khet [>SOFe(II)] [Hg(OH)2], where >SOFe(II) is the total adsorbed Fe(II) concentration; khet values were 5.36 × 10+3, 4.69 × 10+3, and 1.08 × 10+2 L (mol min)−1 for hematite, goethite, and γ-alumina, respectively. Hg(0) production coupled to reduction by Fe(II) may be an important process to consider in ecosystem Hg studies.

  4. Angiotensin II receptors in testes

    SciTech Connect

    Millan, M.A.; Aguilera, G.

    1988-05-01

    Receptors for angiotensin II (AII) were identified and characterized in testes of rats and several primate species. Autoradiographic analysis of the binding of 125I-labeled (Sar1,Ile8)AII to rat, rhesus monkey, cebus monkey, and human testicular slide-mounted frozen sections indicated specific binding to Leydig cells in the interstitium. In rat collagenase-dispersed interstitial cells fractionated by Percoll gradient, AII receptor content was parallel to that of hCG receptors, confirming that the AII receptors are in the Leydig cells. In rat dispersed Leydig cells, binding was specific for AII and its analogs and of high affinity (Kd, 4.8 nM), with a receptor concentration ofmore » 15 fmol/10(6) cells. Studies of AII receptors in rat testes during development reveals the presence of high receptor density in newborn rats which decreases toward the adult age (4934 +/- 309, 1460 +/- 228, 772 +/- 169, and 82 +/- 12 fmol/mg protein at 5, 15, 20, and 30 days of age, respectively) with no change in affinity. At all ages receptors were located in the interstitium, and the decrease in binding was parallel to the decrease in the interstitial to tubular ratio observed with age. AII receptor properties in membrane-rich fractions from prepuberal testes were similar in the rat and rhesus monkey. Binding was time and temperature dependent, reaching a plateau at 60 min at 37 C, and was increased by divalent cations, EGTA, and dithiothreitol up to 0.5 mM. In membranes from prepuberal monkey testes, AII receptors were specific for AII analogs and of high affinity (Kd, 4.2 nM) with a receptor concentration of 7599 +/- 1342 fmol/mg protein. The presence of AII receptors in Leydig cells in rat and primate testes in conjunction with reports of the presence of other components of the renin-angiotensin system in the testes suggests that the peptide has a physiological role in testicular function.« less

  5. Preventive Medicine in World War II. Volume 9, Special Fields

    DTIC Science & Technology

    1969-01-01

    II CLINICAL SERIES Internal Medicine in World War II: Vol. I. Activities of Medical Consultants Vol. II. Infectious Diseases Vol. U)’. Infectious... Diseases and General Medicine Neuropsychiatry in World War II: Vol. 1. Zone of Interior Preventive Medicine in World War II: Vol. II. Environmental Hygiene...Vol. III. Personal Health Measures and Immunization Vol. IV. Communicable Diseases Transmitted Chiefly Through Respiratory and Alimentary Tracts Vol

  6. Database for mobile group II introns.

    PubMed

    Dai, Lixin; Toor, Navtej; Olson, Robert; Keeping, Andrew; Zimmerly, Steven

    2003-01-01

    Group II introns are self-splicing RNAs and retroelements found in bacteria and lower eukaryotic organelles. During the past several years, they have been uncovered in surprising numbers in bacteria due to the genome sequencing projects; however, most of the newly sequenced introns are not correctly identified. We have initiated an ongoing web site database for mobile group II introns in order to provide correct information on the introns, particularly in bacteria. Information in the web site includes: (1) introductory information on group II introns; (2) detailed information on subfamilies of intron RNA structures and intron-encoded proteins; (3) a listing of identified introns with correct boundaries, RNA secondary structures and other detailed information; and (4) phylogenetic and evolutionary information. The comparative data should facilitate study of the function, spread and evolution of group II introns. The database can be accessed at http://www.fp.ucalgary.ca/group2introns/.

  7. Assaying topoisomerase II checkpoints in yeast.

    PubMed

    Furniss, Katherine; Vas, Amit C J; Lane, Andrew; Clarke, Duncan J

    2009-01-01

    Topoisomerase II activity is crucial to maintain genome stability through the removal of catenanes in the DNA formed during DNA replication and scaffolding the mitotic chromosome. Perturbed Topo II activity causes defects in chromosome segregation due to persistent catenations and aberrant DNA condensation during mitosis. Recently, novel top2 alleles in the yeast Saccharomyces cerevisiae revealed a checkpoint control that responds to perturbed Topo II activity. Described in this chapter are protocols for assaying the phenotypes seen in top2 mutants on a cell biological basis in live cells: activation of the Topo II checkpoint using spindle morphology, chromosome condensation using fluorescently labeled chromosomal loci, and cell cycle progression by flow cytometry. Further characterization of this novel checkpoint is warranted so that we can further our understanding of the cell cycle, genomic stability, and the possibility of identifying novel drug targets.

  8. Far Outer Galaxy H II Regions

    NASA Technical Reports Server (NTRS)

    Rudolph, A. L.; deGues, E. J.; Brand, J.; Wouterloot, J. G. A.; Gross, Anthony R. (Technical Monitor)

    1994-01-01

    We have made a multifrequency (6, 3.6, and 2 cm), high-resolution (3"-6"), radio continuum survey of IRAS selected sources from the catalogue of Wouterloot & Brand (1989) to search for and study H II regions in the far outer Galaxy. We identified 31 sources in this catalog with well determined galactocentric distances, and with R approx.. greater than 15 kpc and L(sub FIR) approx.greater than 10(exp 4) solar luminosity, indicating the presence of high-mass star-formation. We have observed 11 of these sources with the Very Large Array (VLA). We observed the sources at 6 and 2 cm using "scaled arrays", making possible a direct and reliable comparison of the data at these two wavelengths for the determination of spectral indices. We detected a total of 12 radio sources, of which 10 have spectral indices consistent with optically-thin free-free emission from H II regions. Combined with previous VLA observations by other investigators, we have data on a total of 15 H II regions at galactocentric distances of 15 to 18.2kpc, among the most remote H II regions found in our Galaxy. The sizes of the H II regions range from approx. less than 0.10 to 2.3 pc. Using the measured fluxes and sizes, we determine the electron densities, emission measures, and excitation parameters of the H II regions, as well as the fluxes of Lyman continuum photons needed to keep the nebulae ionized. The sizes and electron densities are consistent with most of the sources detected in this survey being compact or ultracompact H II regions. Seven of the fifteen H II regions have sizes approx. less than 0.20 pc. Assuming simple pressure-driven expansion of the H II regions, these sizes indicate ages approx. less than 5 x 10(exp 4) yr, or only 1% of the lifetime of an O star, which implies an unlikely overabundance of O stars in the outer Galaxy. Thus, the large number of compact H II regions suggests that the time these regions spend in a compact phase must be much longer than their dynamical

  9. Central Drift Chamber for Belle-II

    NASA Astrophysics Data System (ADS)

    Taniguchi, N.

    2017-06-01

    The Central Drift Chamber (CDC) is the main device for tracking and identification of charged particles for Belle-II experiment. The Belle-II CDC is cylindrical wire chamber with 14336 sense wires, 2.3 m-length and 2.2 m-diameter. The wire chamber and readout electronics have been completely replaced from the Belle CDC. The new readout electronics system must handle higher trigger rate of 30 kHz with less dead time at the design luminosity of 8 × 1035 cm-2s-1. The front-end electronics are located close to detector and send digitized signal through optical fibers. The Amp-Shaper-Discriminator chips, FADC and FPGA are assembled on a single board. Belle-II CDC with readout electronics has been installed successfully in Belle structure in October 2016. We will present overview of the Belle-II CDC and status of commissioning with cosmic ray.

  10. Alternatives to type II cement : final report.

    DOT National Transportation Integrated Search

    1978-01-01

    Concrete mixtures incorporating fly ash were investigated as possible alternatives to mixtures utilizing Type II cements. The mixture characteristics considered were strength, resistance to freezing and thawing and sulfates, heat of hydration, and vo...

  11. Pavement performance evaluation, phase II : data collection.

    DOT National Transportation Integrated Search

    2008-12-01

    Phase I and II of this study tested approximately 1500 rehabilitated pavements (asphalt and PCC) : throughout the State. These pavements ranged from 5 to 15 years old and were intended to develop a : snapshot of how various rehabilitations were perfo...

  12. Astronomical results from SHARC-II

    NASA Astrophysics Data System (ADS)

    Staguhn, Johannes G.; Benford, Dominic J.; Moseley, S. Harvey; Dowell, C. Darren

    2004-03-01

    The Submillimeter High Angular Resolution Camera (SHARC-II) is a facility instrument for far-infrared (350μm) imaging at the Caltech Submillimeter Observatory (CSO). With 384 pixels, SHARC-II uses the world's largest bolometer array for astronomical observations. SHARC-II is most efficiently utilized for observations of extended sources and for deep sky surveys. The low 1/f detector noise allows total power measurements without the need to observe an emission free ``off position''. This is possible because the sky emission can be distinguished from the celestial emission when the array scans over the sky at sufficient speed. Here we present a representative set of SHARC-II observations, which highlight the capabilities of the instrument. The observations show the submillimeter continuum emission from our own Galactic center, the nearby galaxy M51, and the gravitationally lensed high-z Cloverleaf galaxy H1413+1143.

  13. Tory II-C safety analysis report

    SciTech Connect

    Goldberg, E.

    1963-04-01

    Declassified 26 Nov 1973. A description is given of the Tory II-C reactor along with its peripheral equipment and the Pluto test facility. Information is included on nuclear design, general reactor operation, and hazards of operation. (JRD)

  14. Morristown Alternative Transportation Study Phase II.

    DOT National Transportation Integrated Search

    2005-10-14

    This report summarizes the Phase II planning effort conducted by the park and the US Department of Transportation's Volpe Center (the Volpe Center) to articulate a viable park-community pilot transit service for Morristown National Historical Park. M...

  15. Optics for the Queen Elizabeth II telescope.

    PubMed

    Odgers, G J

    1967-10-01

    Details are given of the design considerations for the mounting, finishing, and alignment of the optics for the Queen Elizabeth II telescope. Optical tolerances and test procedures are also discussed.

  16. Zodiac II: Debris Disk Imaging Potential

    NASA Technical Reports Server (NTRS)

    Traub Wesley; Bryden, Geoff; Stapelfeldt, Karl; Chen, Pin; Trauger, John

    2011-01-01

    Zodiac II is a proposed coronagraph on a balloon-borne platform, for the purpose of observing debris disks around nearby stars. Zodiac II will have a 1.2-m diameter telescope mounted in a balloon-borne gondola capable of arcsecond quality pointing, and with the capability to make long-duration (several week) flights. Zodiac II will have a coronagraph able to make images of debris disks, meaning that its scattered light speckles will be at or below an average contrast level of about 10(exp -7) in three narrow (7 percent) bands centered on the V band, and one broad (20%) one at I band. We will discuss the potential science to be done with Zodiac II.

  17. Inhibition of photosystem II-dependent phosphorylation

    SciTech Connect

    Gould, J.M.

    1975-01-01

    Photophosphorylation supported by the coupling site associated with Photosystem II electron transport (coupling site II) is 50 to 60 times less sensitive to the energy transfer inhibitor HgCl/sub 2/ than phosphorylation supported by the coupling site associated with Photosystem I electron transport (coupling site I). Coupling site II phosphorylation is only about 2 times less sensitive to the lipophilic mercurial p-hydroxymercuribenzoate (PHMB), however. Both coupling sites are equally sensitive to CF/sub 1/ antiserum. These results suggest that a portion of the energy conserving apparatus associated with coupling site II is in a more hydrophobic environment than the corresponding apparatus associatedmore » with coupling site I. 21 references, 2 figures, 1 table.« less

  18. North America - The Energy Picture II

    DTIC Science & Technology

    2006-01-01

    electricity generation . North America – The Energy Picture II 10 (3) North America – Energy Supply Proved Reserves of Conventional Crude Oil...North America – The Energy Picture II 12 North American Electricity Generation Electricity Power Generation Capacity, 2004 (Gigawatts) 107 47...968 Canada Mexico United States Total Capacity = 1,112 gigawatts • In 2004, North America had 1,122 gigawatts of electric power generation capacity

  19. Astronomy from large databases II. Proceedings.

    NASA Astrophysics Data System (ADS)

    Heck, A.; Murtagh, F.

    The present volume gathers together the invited talks and the posters presented at the conference on Astronomy from Large Databases II (ALD-II) organized by the Strasbourg Astronomical Observatory in the city of Haguenau, France. This meeting was a follow-up event to the 1987 conference on Astronomy from Large Databases organized by the Space Telescope - European Coordinating Facility in Garching, Germany - see Abstr. 46.012.015.

  20. Preferred crystallographic orientation in the ice I ← II transformation and the flow of ice II

    USGS Publications Warehouse

    Bennett, K.; Wenk, H.-R.; Durham, W.B.; Stern, L.A.; Kirby, S.H.

    1997-01-01

    The preferred crystallographic orientation developed during the ice I ← II transformation and during the plastic flow of ice II was measured in polycrystalline deuterium oxide (D2O) specimens using low-temperature neutron diffraction. Samples partially transformed from ice I to II under a non-hydrostatic stress developed a preferred crystallographic orientation in the ice II. Samples of pure ice II transformed from ice I under a hydrostatic stress and then when compressed axially, developed a strong preferred orientation of compression axes parallel to (1010). A match to the observed preferred orientation using the viscoplastic self-consistent theory was obtained only when (1010) [0001] was taken as the predominant slip system in ice II.

  1. Electrochemical, Antifungal, Antibacterial and DNA Cleavage Studies of Some Co(II), Ni(II), Cu(II) and Zn(II)-Copolymer Complexes

    PubMed Central

    Dhanaraj, C. Justin

    2008-01-01

    Cyclic voltammetric measurements were performed for Co(II), Ni(II), Cu(II) and Zn(II) complexes of 1 : 1 alternating copolymer, poly(3-nitrobenzylidene-1-naphthylamine-co-succinic anhydride) (L) and Ni(II) and Cu(II) complexes of 1 : 1 alternating copolymer, poly(3-nitrobenzylidene-1-naphthylamine-co-methacrylic acid) (L1). The in vitro biological screening effects of the investigated compounds were tested against the fungal species including Aspergillus niger, Rhizopus stolonifer, Aspergillus flavus, Rhizoctonia bataicola and Candida albicans and bacterial species including Staphylococcus aureus, Escherichia coli, Klebsiella pneumaniae, Proteus vulgaris and Pseudomonas aeruginosa by well diffusion method. A comparative study of inhibition values of the copolymers and their complexes indicates that the complexes exhibit higher antimicrobial activity. Copper ions are proven to be essential for the growth-inhibitor effect. The extent of inhibition appeared to be strongly dependent on the initial cell density and on the growth medium. The nuclease activity of the above metal complexes were assessed by gel electrophoresis assay and the results show that the copper complexes can cleave pUC18 DNA effectively in presence of hydrogen peroxide compared to other metal complexes. The degradation experiments using Rhodamine B dye indicate that the hydroxyl radical species are involved in the DNA cleavage reactions. PMID:23997637

  2. Synthesis and characterization of hydroxyapatite nanoparticles impregnated on apple pomace to enhanced adsorption of Pb(II), Cd(II), and Ni(II) ions from aqueous solution.

    PubMed

    Chand, Piar; Pakade, Yogesh B

    2015-07-01

    Hydroxyapatite nanoparticles were synthesized, characterized, and impregnated onto apple pomace surface (HANP@AP) for efficient removal of Pb(II), Cd(II), and Ni(II) ions from water. HANP@AP was characterized by Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), energy-dispersive spectroscopy (EDS), transmission electron microscope (TEM), X-ray diffraction (XRD), and surface area analysis. Batch sorption studies were carried out to investigate the influence of different parameters as amount of dose (g), pH, time (min), and initial concentration (mg L(-1)) on adsorption process. Experimental kinetic data followed pseudo-second-order model and equilibrium data well fitted to Langmuir adsorption model with maximum adsorption capacities of 303, 250, and 100 mg g(-1) for Pb(II), Cd(II), and Ni(II) ions, respectively. Competitive adsorption of Pb(II), Cd(II), and Ni(II) ions in presences of each other was studied to evaluate the removal efficiency of HANP@AP against multi metal-loaded water. HANP@AP was successfully applied to real industrial wastewater with 100 % removal of all three metal ions even at high concentration. HANP@AP could be recycled for four, four, and three cycles in case of Pb(II), Cd(II) and Ni(II), respectively. The study showed that HANP@AP is fast, cost effective, and environmental friendly adsorbent for removal of Pb(II), Cd(II), and Ni(II) ions from real industrial wastewater.

  3. Coronal type II bursts and interplanetary type II bursts: Distinct shock drivers

    NASA Astrophysics Data System (ADS)

    Suryanarayana, G. S.

    2012-02-01

    We study solar radio type II bursts combining with Wind/WAVES type II bursts and coronal mass ejections (CMEs). The aim of the present work is to investigate the effectiveness of shocks to cause type II bursts in the solar corona and the interplanetary space. We consider the following findings. The distribution of the cessation heights of type II emission is confined to a rather narrow range of height than the distribution of the heights of start frequencies. This is suggestive of the presence of a gradient for the Alfvén speed from the heliocentric height of ˜1.4 solar radii. The range of the kinetic energy of CMEs associated with coronal type II emission taken together with the suggested computation method and the Alfvén speed gradient, indicates the limit to the height up to which type II emission could be expected. This height is ˜2 solar radii from the center of the Sun. Further, the large time gap between the cessation time and heights of coronal type II emission and the commencement time and heights of most of the IP type II bursts do not account for the difference between the two heights and the average shock speed. Also, there is clear difference in the magnitude of the kinetic energies and the distinct characteristics of the CMEs associated with coronal and IP type II bursts. Hence, we suggest that in most instances the coronal type II bursts and IP type II bursts occur due to distinct shocks. We also address the question of the origin of type II bursts and discuss the possible explanation of observed results.

  4. Cu(II) and Zn(II) adsorption capacity of three different clay liner materials.

    PubMed

    Musso, T B; Parolo, M E; Pettinari, G; Francisca, F M

    2014-12-15

    Sorption of Cu(II) and Zn(II) on three natural clays meeting the international requirements for use as liners was evaluated by means of batch tests. The purpose of this research was to determine the retention capacities of the clays for metal cations commonly present in urban solid waste leachates. The pH and ionic strength conditions were set at values frequently found in real leachates. The changes observed in the XRD patterns and FTIR spectra upon adsorption can be considered an evidence of clay-metal electrostatic interaction. The Langmuir model was found to best describe the sorption processes, offering maximum sorption capacities from 8.16 to 56.89 mg/g for Cu(II) and from 49.59 to 103.83 mg/g for Zn(II). All samples remove more Zn(II) than Cu(II), which may be related to the different geometry of the hydrated Cu(II) cation. The total amount of metal sorption was strongly influenced by the total specific surface area, the presence of carbonates and the smectite content of the clays. In addition to their known quality as physical barriers, the adsorbed amounts obtained indicate the suitability of the tested clays to contribute to the retardation of Cu(II) and Zn(II) transport through clay liners. Copyright © 2014 Elsevier Ltd. All rights reserved.

  5. Electrochemical studies of DNA interaction and antimicrobial activities of MnII, FeIII, CoII and NiII Schiff base tetraazamacrocyclic complexes

    NASA Astrophysics Data System (ADS)

    Kumar, Anuj; Vashistha, Vinod Kumar; Tevatia, Prashant; Singh, Randhir

    2017-04-01

    Tetraazamacrocyclic complexes of MnII, FeIII, CoII and NiII have been synthesized by template method. These tetraazamacrocycles have been analyzed with various techniques like molar conductance, IR, UV-vis, mass spectral and cyclic voltammetric studies. On the basis of all these studies, octahedral geometry has been assigned to these tetraazamacrocyclic complexes. The DNA binding properties of these macrocyclic complexes have been investigated by electronic absorption spectra, fluorescence spectra, cyclic voltammetric and differential pulse voltammetric studies. The cyclic voltammetric data showed that ipc and ipa were effectively decreased in the presence of calf thymus DNA, which is a strong evidence for the interaction of these macrocyclic complexes with the calf thymus DNA (ct-DNA). The heterogeneous electron transfer rate constant found in the order: KCoII > KNiII > KMnII which indicates that CoII macrocyclic complex has formed a strong intercalated intermediate. The Stern-Volmer quenching constant (KSV) and voltammetric binding constant were found in the order KSV(CoII) > KSV(NiII) > KSV(MnII) and K+(CoII) > K+(NiII) > K+(MnII) which shows that CoII macrocyclic complex exhibits the high interaction affinity towards ct-DNA by the intercalation binding. Biological studies of the macrocyclic complexes compared with the standard drug like Gentamycin, have shown antibacterial activities against E. coli, P. aeruginosa, B. cereus, S. aureus and antifungal activity against C. albicans.

  6. Ionized gas in the Scutum spiral arm as traced in [N II] and [C II

    NASA Astrophysics Data System (ADS)

    Langer, W. D.; Velusamy, T.; Goldsmith, P. F.; Pineda, J. L.; Chambers, E. T.; Sandell, G.; Risacher, C.; Jacobs, K.

    2017-11-01

    Context. The warm ionized medium (WIM) occupies a significant fraction of the Galactic disk. Determining the WIM properties at the leading edge of spiral arms is important for understanding its dynamics and cloud formation. Aims: We derive the properties of the WIM at the inner edge of the Scutum arm tangency, which is a unique location in which to disentangle the WIM from other components, using the ionized gas tracers C+ and N+. Methods: We use high spectral resolution [C II] 158 μm and [N II] 205 μm fine structure line observations taken with the upGREAT and GREAT instruments, respectively, on SOFIA, along with auxiliary H I and 13CO observations. The observations consist of samples in and out of the Galactic plane along 18 lines of sight (LOS) between longitude 30° and 32°. Results: We detect strong [N II] emission throughout the Scutum tangency. At VLSR = 110 to 125 km s-1 where there is little, if any, 13CO, we are able to disentangle the [N II] and [C II] emission that arises from the WIM at the arm's inner edge. We find an average electron density 0.9 cm-3 in the plane, and 0.4 cm-3 just above the plane. The [N II] emission decreases exponentially with latitude with a scale height 55 pc. For VLSR< 110 km s-1 there is [N II] emission tracing highly ionized gas throughout the arm's molecular layer. This ionized gas has a high density, n(e) 30 cm-3, and a few percent filling factor. We also find evidence for [C II] absorption by foreground gas. Conclusions: [N II] and [C II] observations at the Scutum arm tangency reveal a highly ionized gas with average electron density about 10 to 20 times those of the interarm WIM, and is best explained by a model in which the interarm WIM is compressed as it falls into the potential well of the arm. The widespread distribution of [N II] in the molecular layers shows that high density ionized gas is distributed throughout the Scutum arm. The electron densities derived from [N II] for these molecular cloud regions are 30

  7. Selective Hg(II) adsorption from aqueous solutions of Hg(II) and Pb(II) by hydrolyzed acrylamide-grafted PET films.

    PubMed

    Rahman, Nazia; Sato, Nobuhiro; Sugiyama, Masaaki; Hidaka, Yoshiki; Okabe, Hirotaka; Hara, Kazuhiro

    2014-01-01

    Selective Hg(II) adsorption from aqueous solutions of Hg(II) and Pb(II) using hydrolyzed acrylamide (AAm)-grafted polyethylene terephthalate (PET) films was examined to explore the potential reuse of waste PET materials. Selective recovery of Hg(II) from a mixture of soft acids with similar structure, such as Hg(II) and Pb(II), is important to allow the reuse of recovered Hg(II). An adsorbent for selective Hg(II) adsorption was prepared by γ-ray-induced grafting of AAm onto PET films followed by partial hydrolysis through KOH treatment. The adsorption capacity of the AAm-grafted PET films for Hg(II) ions increased from 15 to 70 mg/g after partial hydrolysis because of the reduction of hydrogen bonding between -CONH2 groups and the corresponding improved access of metal ions to the amide groups. The prepared adsorbent was characterized by Fourier transform infrared spectroscopy and scanning electron microscopy. The absorbent film showed high selectivity for the adsorption of Hg(II) over Pb(II) throughout the entire initial metal concentration range (100-500 mg/L) and pH range (2.2-5.6) studied. The high selectivity is attributed to the ability of Hg(II) ions to form covalent bonds with the amide groups. The calculated selectivity coefficient for the adsorbent binding Hg(II) over Pb(II) was 19.2 at pH 4.5 with an initial metal concentration of 100 mg/L. Selective Hg(II) adsorption equilibrium data followed the Langmuir model and kinetic data were well fitted by a pseudo-second-order equation. The adsorbed Hg(II) and Pb(II) ions were effectively desorbed from the adsorbent film by acid treatment, and the regenerated film showed no marked loss of adsorption capacity upon reuse for selective Hg(II) adsorption.

  8. Statistics of equivalent width data and new oscillator strengths for Si II, Fe II, and Mn II. [in interstellar medium

    NASA Technical Reports Server (NTRS)

    Van Buren, Dave

    1986-01-01

    Equivalent width data from Copernicus and IUE appear to have an exponential, rather than a Gaussian distribution of errors. This is probably because there is one dominant source of error: the assignment of the background continuum shape. The maximum likelihood method of parameter estimation is presented for the case of exponential statistics, in enough generality for application to many problems. The method is applied to global fitting of Si II, Fe II, and Mn II oscillator strengths and interstellar gas parameters along many lines of sight. The new values agree in general with previous determinations but are usually much more tightly constrained. Finally, it is shown that care must be taken in deriving acceptable regions of parameter space because the probability contours are not generally ellipses whose axes are parallel to the coordinate axes.

  9. Chelating Schiff base assisted azide-bridged Mn(II), Ni(II) and Cu(II) magnetic coordination polymers.

    PubMed

    Bai, Shi-Qiang; Fang, Chen-Jie; He, Zheng; Gao, En-Qing; Yan, Chun-Hua; Hor, T S Andy

    2012-11-21

    Four new Mn(II), Ni(II) and Cu(II) coordination polymers [Mn2(L1)(μ(1,1)-N3)2(μ(1,3)-N3)2]n (1), [Ni(L2)2(μ(1,3)-N3)]n(ClO4)n (2), [Cu(L3)(μ(1,1)-N3)(N3)]n (3) and [Cu(L4)(μ(1,1)-N3)2]n (4) (L1 = N,N′-bis(2-pyridylmethylene)ethane-1,2-diamine, L2 = N-(2-pyridylmethylene)methylamine, L3 = N-(2-pyridylmethylene)-3-pyridylamine, L4 = N-(2-pyridylmethylene)-tbutylamine) have been synthesized and characterized by single-crystal X-ray analysis and magnetic measurements. Complex 1 indicates a stoichiometry-dependent structural change (based on Mn:L1:N3 = 2:1:4 molar ratio) and consists of two-dimensional (2-D) (4,4) net layers, in which Mn(II) centers are co-bridged by single end-to-end (EE), double end-on (EO) azide and chelate-bridging L1 ligands. Complex 2 shows a single EE azide-bridged one-dimensional (1-D) Ni(II) chain. Complexes 3 and 4 indicate single EO and double EO azide-bridged 1-D Cu(II) chains, respectively. Complex 1 exhibits weak ferromagnetism due to its intra-layer spin-canting with T(c) = 20 K. Complex 2 shows an unusual intra-chain ferromagnetic coupling and spin-canting behaviour. Both complexes 3 and 4 exhibit intra-chain antiferromagnetic interactions. Magneto-structural parameters for these related complexes were also discussed.

  10. An updated Type II supernova Hubble diagram

    NASA Astrophysics Data System (ADS)

    Gall, E. E. E.; Kotak, R.; Leibundgut, B.; Taubenberger, S.; Hillebrandt, W.; Kromer, M.; Burgett, W. S.; Chambers, K.; Flewelling, H.; Huber, M. E.; Kaiser, N.; Kudritzki, R. P.; Magnier, E. A.; Metcalfe, N.; Smith, K.; Tonry, J. L.; Wainscoat, R. J.; Waters, C.

    2018-03-01

    We present photometry and spectroscopy of nine Type II-P/L supernovae (SNe) with redshifts in the 0.045 ≲ z ≲ 0.335 range, with a view to re-examining their utility as distance indicators. Specifically, we apply the expanding photosphere method (EPM) and the standardized candle method (SCM) to each target, and find that both methods yield distances that are in reasonable agreement with each other. The current record-holder for the highest-redshift spectroscopically confirmed supernova (SN) II-P is PS1-13bni (z = 0.335-0.012+0.009), and illustrates the promise of Type II SNe as cosmological tools. We updated existing EPM and SCM Hubble diagrams by adding our sample to those previously published. Within the context of Type II SN distance measuring techniques, we investigated two related questions. First, we explored the possibility of utilising spectral lines other than the traditionally used Fe IIλ5169 to infer the photospheric velocity of SN ejecta. Using local well-observed objects, we derive an epoch-dependent relation between the strong Balmer line and Fe IIλ5169 velocities that is applicable 30 to 40 days post-explosion. Motivated in part by the continuum of key observables such as rise time and decline rates exhibited from II-P to II-L SNe, we assessed the possibility of using Hubble-flow Type II-L SNe as distance indicators. These yield similar distances as the Type II-P SNe. Although these initial results are encouraging, a significantly larger sample of SNe II-L would be required to draw definitive conclusions. Tables A.1, A.3, A.5, A.7, A.9, A.11, A.13, A.15 and A.17 are also available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (http://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/611/A25

  11. Specialized lineages of bacterial group II introns.

    PubMed

    Michel, François; Costa, Maria; Doucet, Aurélien J; Ferat, Jean-Luc

    2007-04-01

    The Avi.groEL intron of Azotobacter vinelandii, which interrupts the termination codon of the groEL gene, is shown to belong to a monophyletic subset of bacterial group II introns that share a large insertion at their 5' extremity and a peculiar genetic localization. Some of these introns are inserted within, right next to, or very close to, a stop codon while others are located immediately 3' of, or close to, an initiation codon. After subgroup IIC introns, which target rho-independent transcription terminators, this is the second instance of a genetically specialized lineage of bacterial group II introns. Both the members of subgroup IIC and the relatives of Avi.groEL stand in contrast against the rest of group II retrotransposons in that features other than sequence must be used in target recognition. Among other specialized characters that could unite the two subgroups are: (i) the presence, next to the 5' splice site, of conserved RNA structures incompatible with the active fold of the group II ribozyme; and (ii) the likely involvement of the ribosome in the facilitation of the splicing process.

  12. Summary of CPAS Gen II Parachute Analysis

    NASA Technical Reports Server (NTRS)

    Morris, Aaron L.; Bledsoe, Kristin J.; Fraire, Usbaldo, Jr.; Moore, James W.; Olson, Leah M.; Ray, Eric

    2011-01-01

    The Orion spacecraft is currently under development by NASA and Lockheed Martin. Like Apollo, Orion will use a series of parachutes to slow its descent and splashdown safely. The Orion parachute system, known as the CEV Parachute Assembly System (CPAS), is being designed by NASA, the Engineering and Science Contract Group (ESCG), and Airborne Systems. The first generation (Gen I) of CPAS testing consisted of thirteen tests and was executed in the 2007-2008 timeframe. The Gen I tests provided an initial understanding of the CPAS parachutes. Knowledge gained from Gen I testing was used to plan the second generation of testing (Gen II). Gen II consisted of six tests: three singleparachute tests, designated as Main Development Tests, and three Cluster Development Tests. Gen II required a more thorough investigation into parachute performance than Gen I. Higher fidelity instrumentation, enhanced analysis methods and tools, and advanced test techniques were developed. The results of the Gen II test series are being incorporated into the CPAS design. Further testing and refinement of the design and model of parachute performance will occur during the upcoming third generation of testing (Gen III). This paper will provide an overview of the developments in CPAS analysis following the end of Gen I, including descriptions of new tools and techniques as well as overviews of the Gen II tests.

  13. LCLS-II Cryomodules Production at Fermilab

    SciTech Connect

    Arkan, Tug; Grimm, Chuck; Kaluzny, Joshua

    2017-05-01

    LCLS-II is an upgrade project for the linear coherent light source (LCLS) at SLAC. The LCLS-II linac will consist of thirty-five 1.3 GHz and two 3.9 GHz superconducting RF continuous wave (CW) cryomodules that Fermilab and Jefferson Lab (JLab) will assemble in collaboration with SLAC. The LCLS-II 1.3 GHz cryomodule design is based on the European XFEL pulsed-mode cryomodule design with modifications needed for CW operation. Fermilab and JLab will each assemble and test a prototype 1.3 GHz cryomodule to assess the results of the CW modifications, in advance of 16 and 17 production 1.3 GHz cryomodules, respectively. Fermilab ismore » solely responsible for the 3.9 GHz cryomodules. After the prototype cryomodule tests are complete and lessons learned incorporated, both laboratories will increase their cryomodule production rates to meet the challenging LCLS-II project requirement of approximately one cryomodule per month per laboratory. This paper presents the Fermilab Cryomodule Assembly Facility (CAF) infrastructure for LCLS-II cryomodule production, the Fermilab prototype 1.3 GHz CW cryomodule (pCM) assembly and readiness for production assembly.« less

  14. The PIP-II Conceptual Design Report

    SciTech Connect

    Ball, M.; Burov, A.; Chase, B.

    2017-03-01

    The Proton Improvement Plan-II (PIP-II) encompasses a set of upgrades and improvements to the Fermilab accelerator complex aimed at supporting a world-leading neutrino program over the next several decades. PIP-II is an integral part of the strategic plan for U.S. High Energy Physics as described in the Particle Physics Project Prioritization Panel (P5) report of May 2014 and formalized through the Mission Need Statement approved in November 2015. As an immediate goal, PIP-II is focused on upgrades to the Fermilab accelerator complex capable of providing proton beam power in excess of 1 MW on target at the initiation of themore » Long Baseline Neutrino Facility/Deep Underground Neutrino Experiment (LBNF/DUNE) program, currently anticipated for the mid- 2020s. PIP-II is a part of a longer-term goal of establishing a high-intensity proton facility that is unique within the world, ultimately leading to multi-MW capabilities at Fermilab....« less

  15. Centrifuge workers study. Phase II, completion report

    SciTech Connect

    Wooten, H.D.

    1994-09-01

    Phase II of the Centrifuge Workers Study was a follow-up to the Phase I efforts. The Phase I results had indicated a higher risk than expected among centrifuge workers for developing bladder cancer when compared with the risk in the general population for developing this same type of cancer. However, no specific agent could be identified as the causative agent for these bladder cancers. As the Phase II Report states, Phase I had been limited to workers who had the greatest potential for exposure to substances used in the centrifuge process. Phase II was designed to expand the survey tomore » evaluate the health of all employees who had ever worked in Centrifuge Program Departments 1330-1339 but who had not been interviewed in Phase I. Employees in analytical laboratories and maintenance departments who provided support services for the Centrifuge Program were also included in Phase II. In December 1989, the Oak Ridge Associated Universities (ORAU), now known as Oak Ridge Institute for Science and Education (ORISE), was contracted to conduct a follow-up study (Phase II). Phase H of the Centrifuge Workers Study expanded the survey to include all former centrifuge workers who were not included in Phase I. ORISE was chosen because they had performed the Phase I tasks and summarized the corresponding survey data therefrom.« less

  16. Andromeda II as a merger remnant

    NASA Astrophysics Data System (ADS)

    Łokas, Ewa L.; Ebrová, Ivana; Pino, Andrés del; Semczuk, Marcin

    2014-11-01

    Using N-body simulations, we study the origin of prolate rotation observed in the kinematic data for Andromeda II (And II), a dwarf spheroidal satellite of M31. We propose an evolutionary model for the origin of And II involving a merger between two discy dwarf galaxies with different disc scalelengths. The dwarfs are placed on a radial orbit towards each other with their angular momenta inclined by 90 deg. The merger remnant forms a stable triaxial galaxy with rotation only around the longest axis whose origin is naturally explained as due to the symmetry of the initial configuration and the conservation of angular momentum components along the direction of the merger. The stars originating from the two dwarfs show significantly different surface density profiles while having very similar kinematics as required by the data. We also study an alternative scenario for the formation of And II, via tidal stirring of a discy dwarf. While intrinsic rotation occurs naturally in this model as a remnant of the initial rotation of the disc, it is mostly around the shortest axis of the stellar component. We conclude that the velocity distribution in And II is much more naturally explained by a scenario involving a past merger.

  17. 40 CFR Appendix II to Subpart E of... - Sampling Tables

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Sampling Tables II Appendix II to Subpart E of Part 205 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) NOISE..., Subpt. E, App. II Appendix II to Subpart E of Part 205—Sampling Tables Table 1—Model Year Production...

  18. 40 CFR Appendix II to Subpart E of... - Sampling Tables

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Sampling Tables II Appendix II to Subpart E of Part 205 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) NOISE..., Subpt. E, App. II Appendix II to Subpart E of Part 205—Sampling Tables Table 1—Model Year Production...

  19. 49 CFR 238.317 - Class II brake test.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 4 2011-10-01 2011-10-01 false Class II brake test. 238.317 Section 238.317... Requirements for Tier I Passenger Equipment § 238.317 Class II brake test. (a) A Class II brake test shall be.... In these circumstances, a Class II brake test shall be performed prior to the train's departure from...

  20. 49 CFR 238.317 - Class II brake test.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Class II brake test. 238.317 Section 238.317... Requirements for Tier I Passenger Equipment § 238.317 Class II brake test. (a) A Class II brake test shall be.... In these circumstances, a Class II brake test shall be performed prior to the train's departure from...

  1. 49 CFR 238.317 - Class II brake test.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 4 2014-10-01 2014-10-01 false Class II brake test. 238.317 Section 238.317... Requirements for Tier I Passenger Equipment § 238.317 Class II brake test. (a) A Class II brake test shall be.... In these circumstances, a Class II brake test shall be performed prior to the train's departure from...

  2. 49 CFR 238.317 - Class II brake test.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 4 2012-10-01 2012-10-01 false Class II brake test. 238.317 Section 238.317... Requirements for Tier I Passenger Equipment § 238.317 Class II brake test. (a) A Class II brake test shall be.... In these circumstances, a Class II brake test shall be performed prior to the train's departure from...

  3. 49 CFR 238.317 - Class II brake test.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 4 2013-10-01 2013-10-01 false Class II brake test. 238.317 Section 238.317... Requirements for Tier I Passenger Equipment § 238.317 Class II brake test. (a) A Class II brake test shall be.... In these circumstances, a Class II brake test shall be performed prior to the train's departure from...

  4. Adsorption of zinc(II) and copper(II) to Shirasu (pyroclastic flow).

    PubMed

    Isagai, Hiroo

    2008-03-01

    A fundamental study on the adsorption of metal elements on Shirasu, a pyroclastic flow deposit distributed in southern Kyushu, Japan, has been conducted. The adsorption experiment was carried out by a batch method, and by using Zn(II) and Cu(II) under several conditions; the effects of the initial concentration of metal ions, grain size, and pH were investigated. At smaller grain sizes, the amount of Zn(II) and Cu(II) adsorbed increased. At higher pH values, the amount of Zn(II) and Cu(II) adsorbed increased. Plots of the adsorption isotherm indicated that the adsorption of Zn(II) and Cu(II) on Shirasu followed the Langmuir isotherm model, and the Langmuir isotherm constants, W(0) and b, were obtained. W(0) at pH 5.0 was approximately two-times larger than that at pH 3.0. This may reflect an increase in the number of anionic binding sites on the surface of Shirasu with an increase in the pH. The b value for Zn hardly changed with an increase in the pH, and for Cu the value decreased with an increase in the pH. These observations suggest that anionic binding sites have a low stability constant, since the apparent stability constant, b, is obtained as the average of stability constant of all sites on the Shirasu surface.

  5. Adsorption characteristics of Cu(II) and Pb(II) onto expanded perlite from aqueous solution.

    PubMed

    Sari, Ahmet; Tuzen, Mustafa; Citak, Demirhan; Soylak, Mustafa

    2007-09-05

    The adsorption characteristics of Cu(II) and Pb(II) onto expanded perlite (EP) from aqueous solution were investigated with respect to the changes in pH of solution, adsorbent dosage, contact time and temperature of solution. For the adsorption of both metal ions, the Langmuir isotherm model fitted to equilibrium data better than the Freundlich isotherm model. Using the Langmuir model equation, the monolayer adsorption capacity of EP was found to be 8.62 and 13.39 mg/g for Cu(II) and Pb(II) ions, respectively. Dubinin-Radushkevich (D-R) isotherm model was also applied to the equilibrium data and the mean free energies of adsorption were found as 10.82 kJ/mol for Cu(II) and 9.12 kJ/mol for Pb(II) indicating that the adsorption of both metal ions onto EP was taken place by chemical ion-exchange. Thermodynamic functions, the change of free energy (DeltaG degrees ), enthalpy (DeltaH degrees ) and entropy (DeltaS degrees ) of adsorption were also calculated for each metal ions. These parameters showed that the adsorption of Cu(II) and Pb(II) ions onto EP was feasible, spontaneous and exothermic at 20-50 degrees C. Experimental data were also evaluated in terms of kinetic characteristics of adsorption and it was found that adsorption process for both metal ions followed well pseudo-second-order kinetics.

  6. Employability Planning Process. STIP II (Skill Training Improvement Programs Round II).

    ERIC Educational Resources Information Center

    Los Angeles Community Coll. District, CA.

    Four reports are presented detailing procedures for improving the employability of students enrolled in the Los Angeles Community College District's Skill Training Improvement Programs (STIP II). Each report was submitted by one of the four STIP II programs: Los Angeles Southwest College's program for computer programming; the programs for…

  7. Adsorption of Pb(II) and Cd(II) by Squid Ommastrephes bartrami Melanin

    PubMed Central

    Chen, Shiguo; Xue, Changhu; Wang, Jingfeng; Feng, Hui; Wang, Yuming; Ma, Qin; Wang, Dongfeng

    2009-01-01

    The adsorption of Cd(II) and Pb(II) by squid melanin was investigated. At a metal ion concentration of 2 mM/L, the biosorption efficiency of melanin reached 95% for Cd(II) and Pb(II). The maximum content of bound Cd(II) and Pb(II) was 0.93 mM/g and 0.65 mM/g, respectively. Temperature had no obvious effect on the adsorption of the metals, and in a pH range of 4.0–7.0, the adsorption yield was high and stable. Macrosalts such as NaCl, MgCl2, and CaCl2 had no obvious effect on the binding of Pb(II) but greatly diminished the adsorption of Cd(II), which indicated that different functional groups in squid melanin are responsible for their adsorption. IR analysis of metal ion-enriched squid melanin demonstrated that the possible functional groups responsible for metal binding were phenolic hydroxyl (OH), carboxyl (COOH), and amine groups (NH). This study reports a new material for the removal of heavy metals from low-strength wastewater. PMID:20148082

  8. X-ray VS He II lambda 1640 A correlation of II Peg

    NASA Astrophysics Data System (ADS)

    Esendemir, A.; Alev, H. M.

    1992-11-01

    The He II lambda 1640 A emission feature on the IUE spectra of II Peg has been compared with the observed X-ray flux. The atmospheric activity level is determined by comparing the several diagnostic line intensities with the solar case.

  9. A Nozaki-Hiyama-Kishi Ni(II)/Cr(II) coupling approach to the phomactins.

    PubMed

    Mi, B; Maleczka, R E

    2001-05-17

    [reaction: see text] Through a unified synthetic strategy, appropriately functionalized bicyclic starting materials can be elaborated via Ni(II)/Cr(II) macrocylization to [9.3.1] bicycles. Elaboration of these core structures allows access to phomactin C/D analogues and establishes the first synthetic approach to phomactin A affording an intact octahydrochromene/macrocyclic ring system.

  10. AT2 DS II - Accelerator System Design (Part II) - CCC Video Conference

    ScienceCinema

    None

    2017-12-09

    Discussion Session - Accelerator System Design (Part II) Tutors: C. Darve, J. Weisend II, Ph. Lebrun, A. Dabrowski, U. Raich Video Conference with the CERN Control Center. Experts in the field of Accelerator science will be available to answer the students questions. This session will link the CCC and SA (using Codec VC).

  11. Biosorption of copper(II) and lead(II) onto potassium hydroxide treated pine cone powder.

    PubMed

    Ofomaja, A E; Naidoo, E B; Modise, S J

    2010-08-01

    Pine cone powder surface was treated with potassium hydroxide and applied for copper(II) and lead(II) removal from solution. Isotherm experiments and desorption tests were conducted and kinetic analysis was performed with increasing temperatures. As solution pH increased, the biosorption capacity and the change in hydrogen ion concentration in solution increased. The change in hydrogen ion concentration for lead(II) biosorption was slightly higher than for copper(II) biosorption. The results revealed that ion-exchange is the main mechanism for biosorption for both metal ions. The pseudo-first order kinetic model was unable to describe the biosorption process throughout the effective biosorption period while the modified pseudo-first order kinetics gave a better fit but could not predict the experimentally observed equilibrium capacities. The pseudo-second order kinetics gave a better fit to the experimental data over the temperature range from 291 to 347 K and the equilibrium capacity increased from 15.73 to 19.22 mg g(-1) for copper(II) and from 23.74 to 26.27 for lead(II). Activation energy was higher for lead(II) (22.40 kJ mol(-1)) than for copper(II) (20.36 kJ mol(-1)). The free energy of activation was higher for lead(II) than for copper(II) and the values of DeltaH* and DeltaS* indicate that the contribution of reorientation to the activation stage is higher for lead(II) than copper(II). This implies that lead(II) biosorption is more spontaneous than copper(II) biosorption. Equilibrium studies showed that the Langmuir isotherm gave a better fit for the equilibrium data indicating monolayer coverage of the biosorbent surface. There was only a small interaction between metal ions when simultaneously biosorbed and cation competition was higher for the Cu-Pb system than for the Pb-Cu system. Desorption studies and the Dubinin-Radushkevich isotherm and energy parameter, E, also support the ion-exchange mechanism. Copyright 2010 Elsevier Ltd. All rights reserved.

  12. Spectroscopic and thermal degradation behavior of Cr(III), Mn(II), Fe(III), Co(II), Ni(II), Cu(II) and Zn(II) complexes with thiopental sodium anesthesia drug

    NASA Astrophysics Data System (ADS)

    Refat, Moamen S.

    2013-04-01

    A new series of Cr(III), Mn(II), Fe(III), Co(II), Ni(II), Cu(II) and Zn(II) complexes have been synthesized with thiopental sodium anesthesia drug. The elemental analyses of the complexes are confined to stoichiometry of the formulas [M(TPL)3]ṡnH2O (M = Cr(III) or Fe(III); n = 6 or 5), [M(TPL)2(H2O)2]ṡnH2O (M = Mn(II), Co(II) or Ni(II); n = 0 or 4), and [M(TPL)2] (M = Cu(II) or Zn(II); n = 2 or 0) respectively, where TPL is thiopental chelating agent. Structures have been discussed and suggested upon elemental analyses, infrared, Raman, electronic, electron spin resonance, 1H NMR spectral data and magnetic studies. The X-ray powder diffraction (XRD) was performed of metal complexes. The XRD patterns indicate crystalline nature for the complexes. The measured low molar conductance values in dimethylsulfoxide indicate that the complexes are non-electrolyte nature. Spectroscopic discussion refer that coordination take place through three types: Cdbnd N (pyrimidine moiety) nitrogen and C2sbnd S (2-thiolate group) for Cr(III), Mn(II) and Fe(III), C6dbnd O (amido group) oxygen and C2sbnd S (2-thiolate group) for Co(II) and Ni(II), and Cu(II) and Zn(II) ions coordinated via Cdbnd N (pyrimidine moiety) nitrogen, C2dbnd S (2-thiolate group) and C6dbnd O (amido group) oxygen, respectively. The thermal behavior (TG/DTG/DTA) of the complexes was studied and kinetic parameters were determined by Horowitz-Metzger and Coats-Redfern methods. The thiopental and its complexes have been screened for their antimicrobial (G+ and G-) bacteria (Escherichia coli, Staphylococcus aureus, Bacillus subtilis and Pseudomonas aeruginosa) and fungi (Aspergillus flavus and Candida albicans) activities by minimum inhibitory concentration (MIC) method.

  13. Synthesis, investigation and spectroscopic characterization of piroxicam ternary complexes of Fe(II), Fe(III), Co(II), Ni(II), Cu(II) and Zn(II) with glycine and DL-phenylalanine

    NASA Astrophysics Data System (ADS)

    Mohamed, Gehad G.; El-Gamel, Nadia E. A.

    2004-11-01

    The ternary piroxicam (Pir; 4-hydroxy-2-methyl- N-(2-pyridyl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide) complexes of Fe(II), Fe(III), Co(II), Ni(II), Cu(II) and Zn(II) with various amino acids (AA) such as glycine (Gly) or DL-phenylalanine (PhA) were prepared and characterized by elemental analyses, molar conductance, IR, UV-Vis, magnetic moment, diffuse reflectance and X-ray powder diffraction. The UV-Vis spectra of Pir and the effect of metal chelation on the different interligand transitions are discussed in detailed manner. IR and UV-Vis spectra confirm that Pir behaves as a neutral bidentate ligand coordinated to the metal ions via the pyridine- N and carbonyl group of the amide moiety. Gly molecule acted as a uninegatively monodentate ligand and coordinate to the metal ions through its carboxylic group, in addition PhA acted as a uninegatively bidentate ligand and coordinate to the metal ions through its carboxylic and amino groups. All the chelates have octahedral geometrical structures while Cu(II)- and Zn(II)-ternary chelates with PhA have square planar geometrical structures. The molar conductance data reveal that most of these chelates are non electrolytes, while Fe(III)-Pir-Gly, Co(II)-, Ni(II)-, Cu(II)- and Zn(II)-Pir-PhA cheletes were 1:1 electrolytes. X-ray powder diffraction is used as a new tool to estimate the crystallinity of chelates as well as to elucidate their geometrical structures.

  14. PBFA II energy-storage-section design

    NASA Astrophysics Data System (ADS)

    Wilson, J. M.

    PBFA II will be the second thirty-six module accelerator built at Sandia National Laboratories for particle beam fusion feasibility studies. Each module of the machine will deliver 2.8 terawatts to a central experimental chamber. The total power delivered (100 terawatts) is expected to permit ignition scaling studies beginning in 1986. The FBFA II energy storage system consists of thirty-six 6.0-MV, 400-kJ, Marx generators with their high voltage trigger and charging systems, and electro-mechanical output switching system. The current design of this section of the machine is described. Constraints imposed by the existing tank and building are presented, as they relate to locating support systems in the oil section of PBFA II. The charging system and output switches were designed and are described. A conceptual design for the Marx triggering system is also presented. Additional hardware (monitors, grounding connections, etc.) is discussed briefly with design given where available.

  15. Mutagenic effects of lead (II) bromide.

    PubMed

    Maslat, A O; Haas, H J

    1989-12-01

    The mutagenicity of lead (II) bromide (a combustion product of the gasoline additives lead (IV) tetraethyl and 1,2-dibromoethane) was investigated using various strains of bacteria. Taking prodigiosin (the red pigment) production as a marker, lead (II) bromide was found to be mutagenic in S. marcescens, leading to the appearance of white mutant colonies that are unable to produce such a pigment. This compound was also found to be mutagenic in E. coli KMBL1851, resulting in the appearance of rifampicin-resistant mutants in addition to Met+ and His+ revertants. Some of the S. marcescens mutants were found to be reversible, able to resynthesize prodigiosin. Differences in the sensitivity to antibiotics as well as in the biochemical properties were detected between the mutants and their corresponding wild types. Lead (II) bromide gave positive results in the Ames test performed with strain TA 1535.

  16. Mg II profile variations of Zeta Aurigae

    NASA Technical Reports Server (NTRS)

    Ahmad, I. A.; Chapman, R. D.; Kondo, Y.

    1983-01-01

    Variations in the Mg II 2800-A doublet of Zeta Aurigae have been observed. The Mg II profiles deviate from simple P-Cygni profiles in that they exhibit an absorption feature consistent with Chapman's (1981) interpretation of C IV absorption as evidence of a column of accretion onto the B-star component of the binary. The opening angle of the shock cone containing the accretion column is found to exceed 16 deg, implying a stellar wind velocity of approximately 67 km/s, unless the H II region temperature is unusually high. The turbulence velocity of the wind then appears to be about 33 km/s, compared to values of order 10 km/s previously determined closer to the K-star surface.

  17. Sister chromatid segregation in meiosis II

    PubMed Central

    Wassmann, Katja

    2013-01-01

    Meiotic divisions (meiosis I and II) are specialized cell divisions to generate haploid gametes. The first meiotic division with the separation of chromosomes is named reductional division. The second division, which takes place immediately after meiosis I without intervening S-phase, is equational, with the separation of sister chromatids, similar to mitosis. This meiotic segregation pattern requires the two-step removal of the cohesin complex holding sister chromatids together: cohesin is removed from chromosome arms that have been subjected to homologous recombination in meiosis I and from the centromere region in meiosis II. Cohesin in the centromere region is protected from removal in meiosis I, but this protection has to be removed—deprotected”—for sister chromatid segregation in meiosis II. Whereas the mechanisms of cohesin protection are quite well understood, the mechanisms of deprotection have been largely unknown until recently. In this review I summarize our current knowledge on cohesin deprotection. PMID:23574717

  18. Enhanced adsorption of Cu(II) and Cd(II) by phosphoric acid-modified biochars.

    PubMed

    Peng, Hongbo; Gao, Peng; Chu, Gang; Pan, Bo; Peng, Jinhui; Xing, Baoshan

    2017-10-01

    In this research, adsorption of Cu(II) and Cd(II) by biochars was investigated. To enhance the adsorption of these two metal ions, a simple modification of biochars by phosphoric acid (H 3 PO 4 ) was carried out. The surface area was larger and the contents of oxygen-containing functional groups of modified biochars were more than pristine biochars. In comparison with pristine biochar, modified biochars sorbed Cu(II) and Cd(II) much more strongly. Surface area had significant effects on the sorption of Cu(II) and Cd(II) by modified biochars, it also resulted in the higher sorption for the pristine biochar at high pyrolysis temperature. X-ray photoelectron spectroscopy analyses indicated that the quantities of carboxyl (-COOH) and hydroxyl (-OH) functional groups of modified biochars were larger than those of pristine biochar at the same pyrolysis temperature. Compared with that of pristine biochars, the strong ability of -COOH and -OH of modified biochars to form complexes with Cu(II)/Cd(II) ions resulted in higher adsorption of these two metal ions. The phosphorus-containing groups of modified biochars, such as P=O and P=OOH from the result of Fourier transform infrared spectroscopy, interacted and also formed complexes with metal ions, possibly resulting in the enhanced adsorption of Cu(II) and Cd(II). Thus, sorption of metal ions by modified biochars was controlled by the mechanism of surface complexation between oxygen containing functional groups and metals. In general, the H 3 PO 4 modification was an effective method to prepare biochars with a high affinity for the sorption of heavy metals. Copyright © 2017 Elsevier Ltd. All rights reserved.

  19. Intrafibrillar Mineral May be Absent in Dentinogenesis Imperfecta Type II (DI-II)

    SciTech Connect

    Pople, John A

    2001-03-29

    High-resolution synchrotron radiation computed tomography (SRCT) and small angle x-ray scattering (SAXS) were performed on normal and dentinogenesis imperfecta type II (DI-II) teeth. Three normal and three DI-II human third molars were used in this study. The normal molars were unerupted and had intact enamel; donors were female and ranged in age from 18-21y. The DI-II specimens, which were also unerupted with intact enamel, came from a single female donor age 20y. SRCT showed that the mineral concentration was 33% lower on average in the DI-II dentin with respect to normal dentin. The SAXS spectra from normal dentin exhibited low-anglemore » diffraction peaks at harmonics of 67.6 nm, consistent with nucleation and growth of the apatite phase within gaps in the collagen fibrils (intrafibrillar mineralization). In contrast, the low-angle peaks were almost nonexistent in the DI-II dentin. Crystallite thickness was independent of location in both DI-II and normal dentin, although the crystallites were significantly thicker in DI-II dentin (6.8 nm (s.d. = 0.5) vs 5.1 nm (s.d. = 0.6)). The shape factor of the crystallites, as determined by SAXS, showed a continuous progression in normal dentin from roughly one-dimensional (needle-like) near the pulp to two-dimensional (plate-like) near the dentin-enamel junction. The crystallites in DI-II dentin, on the other hand, remained needle-like throughout. The above observations are consistent with an absence of intrafibrillar mineral in DI-II dentin.« less

  20. Competitive adsorption of Cu(II)-EDTA and Cd(II)-EDTA onto TiO{sub 2}

    SciTech Connect

    Yang, J.K.; Davis, A.P.

    1999-08-01

    Cu(II), EDTA, Cu(II)-EDTA, Cd(II)-EDTA, and Cu(II)/Cd(II) and Cu(II)-EDTA/Cd(II)-EDTA competitive adsorption onto TiO{sub 2} has been studied with variation of pH and concentration. For Cu(II) and EDTA, typical cationic and anionic types of adsorption are noted, respectively. Ligand-type adsorption is found for Cu(II)-EDTA and Cd(II)-EDTA under both single and competitive conditions. Surface complexation modeling considered inner-sphere complexation and the diffuse layer model employing MINTEQA2; surface complexes used include Ti-(OH{sub 2})O-Cu{sup +}, Ti-(OH)EDTAH{sub 2}{sup {minus}2}, Ti-(OH)EDTA-Cu{sup {minus}2}, and Ti-(OH)EDTA-Cd{sup {minus}2}. Experimental and model predictions suggest no competitive adsorption between Cu(II) and Cd(II) at 5 {times} 10{sup {minus}5} M. On the other hand,more » adsorption data and model predictions indicate that Cd(II)-EDTA adsorption is favored over that of Cu(II)-EDTA with some competition for adsorption sites. Cd(II)-EDTA Adsorption was only slightly affected by the presence of Cu(II)-EDTA; however, Cu(II)-EDTA adsorption was strongly influenced by the presence of Cd(II)-EDTA, especially as the molar ratio of Cd(II)-EDTA/Cu(II)-EDTA increased. A modified surface complexation constant for Cd(II)-EDTA is required to explain the competitive data, suggesting surface site heterogeneity.« less

  1. Testicular gonadotropin-releasing hormone II receptor (GnRHR-II) knockdown constitutively impairs diurnal testosterone secretion in the boar

    USDA-ARS?s Scientific Manuscript database

    The second mammalian GnRH isoform (GnRH-II) and its specific receptor (GnRHR-II) are highly expressed in the testis, suggesting an important role in testis biology. Gene coding errors prevent the production of GnRH-II and GnRHR-II in many species, but both genes are functional in swine. We have demo...

  2. Psychometric Properties of the Beck Depression Inventory-II (BDI-II) among Community-Dwelling Older Adults

    ERIC Educational Resources Information Center

    Segal, Daniel L.; Coolidge, Frederick L.; Cahill, Brian S.; O'Riley, Alisa A.

    2008-01-01

    The psychometric properties of the Beck Depression Inventory-II (BDI-II) as a self-administered screening tool for depressive symptoms were examined in a sample of community-dwelling older and younger adults. Participants completed the BDI-II, the Center for Epidemiologic Studies Depression Scale, the Coolidge Axis II Inventory, the Perceived…

  3. trans-Bis(hexafluoroantimonato)(phthalocyaninato)copper(II).

    PubMed

    Gardberg, A S; Ibers, J A

    2001-05-01

    The title compound, trans-bis(hexafluoroantimonato-F)(phthalocyaninato-kappa(4)N(29,30,31,32))copper(II), [Cu(SbF(6))(2)(C(32)H(16)N(8))] or Cu(pc)(SbF(6))(2) (pc is phthalocyaninate), comprises a six-coordinate Cu atom, lying on an inversion center, bonded to four N atoms of a phthalocyanine ring and to F atoms of two trans SbF(6)(-) groups. The compound is presumed to consist of a Cu(II) center and a doubly oxidized phthalocyanine ring, by analogy with Cu(pc)(ReO(4))(2).

  4. Delta II ICESAT Second Stage Arrival

    NASA Image and Video Library

    2017-12-18

    The United Launch Alliance Delta II second stage is being transported to Space Launch Complex-2 at Vandenberg Air Force Base in California. NASA's Ice, Cloud and land Elevation Satellite-2 (ICESat-2) will launch later this year on the final Delta II rocket. ICESat-2 will measure the height of a changing Earth, one laser pulse at a time, 10,000 laser pulses a second. The satellite will carry a single instrument, the Advanced Topographic Laser Altimeter System. ICESat-2 will help scientists investigate why, and how much our planet's frozen and icy areas, called the cryosphere, is changing in a warming climate.

  5. Delta II ICESAT Second Stage Arrival

    NASA Image and Video Library

    2017-12-18

    Workers stand with the Delta II second stage inside the horizontal processing facility at Space Launch Complex-2 at Vandenberg Air Force Base in California. NASA's Ice, Cloud and land Elevation Satellite-2 (ICESat-2) will launch later this year on the final Delta II rocket. ICESat-2 will measure the height of a changing Earth, one laser pulse at a time, 10,000 laser pulses a second. The satellite will carry a single instrument, the Advanced Topographic Laser Altimeter System. ICESat-2 will help scientists investigate why, and how much our planet's frozen and icy areas, called the cryosphere, is changing in a warming climate.

  6. Delta II ICESAT Second Stage Arrival

    NASA Image and Video Library

    2017-12-18

    The United Launch Alliance Delta II second stage has arrived at the horizontal processing facility at Space Launch Complex-2 at Vandenberg Air Force Base in California. NASA's Ice, Cloud and land Elevation Satellite-2 (ICESat-2) will launch later this year on the final Delta II rocket. ICESat-2 will measure the height of a changing Earth, one laser pulse at a time, 10,000 laser pulses a second. The satellite will carry a single instrument, the Advanced Topographic Laser Altimeter System. ICESat-2 will help scientists investigate why, and how much our planet's frozen and icy areas, called the cryosphere, is changing in a warming climate.

  7. Naturalness in testable type II seesaw scenarios

    NASA Astrophysics Data System (ADS)

    Dev, P. S. Bhupal; Vila, Clara Miralles; Rodejohann, Werner

    2017-08-01

    New physics coupling to the Higgs sector of the Standard Model can lead to dangerously large corrections to the Higgs mass. We investigate this problem in the type II seesaw model for neutrino mass, where a weak scalar triplet is introduced. The interplay of direct and indirect constraints on the type II seesaw model with its contribution to the Higgs mass is analyzed. The focus lies on testable triplet masses and (sub) eV-scale triplet vacuum expectation values. We identify scenarios that are testable in collider and/or lepton flavor violation experiments, while satisfying the Higgs naturalness criterion.

  8. The PIP-II Reference Design Report

    SciTech Connect

    Lebedev, Valeri,

    2015-06-01

    The Proton Improvement Plan-II (PIP-II) is a high-intensity proton facility being developed to support a world-leading neutrino program over the next two decades at Fermilab. PIP-II is an integral part of the U.S. Intensity Frontier Roadmap as described in the Particle Physics Project Prioritization Panel (P5) report of May 2014 [1]. As an immediate goal PIP-II is focused on upgrades to the Fermilab accelerator complex capable of providing a beam power in excess of 1 MW on target at the initiation of LBNF [1,2] operations. PIP-II is a part of a longer-term concept for a sustained campaign of upgrades andmore » improvements to achieve multi-MW capabilities at Fermilab. PIP-II is based on three major thrusts. They are (1) the recently completed upgrades to the Recycler and Main Injector (MI) for the NOvA experiment, (2) the Proton Improvement Plan [3] currently underway, and (3) the Project X Reference Design [4]. Note that: The Proton Improvement Plan (PIP) consolidates a set of improvements to the existing Linac, Booster, and Main Injector (MI) aimed at supporting 15 Hz Booster beam operation. In combination, the NOvA upgrades and PIP create a capability of delivering 700 kW beam power from the Main Injector at 120 GeV; The scope of the Project X Reference Design Report was aimed well beyond PIP. It described a complete concept for a multi-MW proton facility that could support a broad particle physics program based on neutrino, kaon, muon, and nucleon experiments [5,6]. The Project X conceptual design has evolved over a number of years, incorporating continuous input on physics research goals and advances in the underlying technology development programs [7,8,9]. PIP-II, to high degree, inherits these goals as the goals for future developments and upgrades. This document (PIP-II Reference Design Report) describes an initial step in the development of the Fermilab accelerating complex. The plan described in this Report balances the far-term goals of the Laboratory

  9. Paralysis Episodes in Carbonic Anhydrase II Deficiency.

    PubMed

    Al-Ibrahim, Alia; Al-Harbi, Mosa; Al-Musallam, Sulaiman

    2003-01-01

    Carbonic anhydrase II (CAII) deficiency is an autosomal recessive disorder manifest by osteopetrosis, renal tubular acidosis, and cerebral calcification. Other features include growth failure and mental retardation. Complications of the osteopetrosis include frequent bone fractures, cranial nerve compression, and dental mal-occlusion. A hyper-chloremic metabolic acidosis, sometimes with hypokalemia, occurs due to renal tubular acidosis that may be proximal, distal, or more commonly, the combined type. Such patients may present with global hypotonia, muscle weakness or paralysis. We report a case of CA II deficiency with recurrent attacks of acute paralysis which was misdiagnosed initially as Guillian-Barre syndrome.

  10. Diagnostic front end for BESSY II.

    PubMed

    Peatman, W B; Holldack, K

    1998-05-01

    For BESSY II, synchrotron radiation beam diagnostics will be incorporated in both the insertion-device front ends and the dipole-beamline front ends. In order to gain a complete picture of the source characteristics, a diagnostic front end has been designed and tested for dipole radiation. This consists of (i) a pinhole array imaging system, (ii) a double-blade system for the determination of the vertical center of gravity of the synchrotron radiation fan, and (iii) a Bragg-Fresnel multilayer system for the most precise image information about the source size and shape.

  11. THE TORY II-A REACTOR PROGRAM

    SciTech Connect

    Reynolds, H.

    1963-09-01

    The design requirements, the findamental design problems, and the test facility for the Tory II-A reactor are described. Tory II-A was an engineering test reactor, built and tested to gain information on the materials, engineering, and physics problems. The available air allowed fullpower full-temperature operation of the reactor for a period of less thand two minutes. The reactor was first operated at 50 Mw in May 1961. In late September and early October of 1961 the reactor was tsken to high power three times in succession. These runs were followed by remote disassembly of the reactor. (M.C.G.)

  12. Delta II Second stage lift and mate

    NASA Image and Video Library

    2007-01-19

    On Pad 17-B at Cape Canaveral Air Force Station, the Delta II second stage is moved inside level 9 of the tower. It will be mated with the first stage already in place. The Delta II is the launch vehicle for the THEMIS spacecraft. THEMIS consists of five identical probes, the largest number of scientific satellites ever launched into orbit aboard a single rocket. This unique constellation of satellites will resolve the tantalizing mystery of what causes the spectacular sudden brightening of the aurora borealis and aurora australis - the fiery skies over the Earth's northern and southern polar regions. THEMIS is scheduled to launch Feb. 15 from Cape Canaveral Air Force Station.

  13. Spectroscopic, DNA binding ability, biological activity, DFT calculations and non linear optical properties (NLO) of novel Co(II), Cu(II), Zn(II), Cd(II) and Hg(II) complexes with ONS Schiff base

    NASA Astrophysics Data System (ADS)

    Abdel Aziz, Ayman A.; Elantabli, Fatma M.; Moustafa, H.; El-Medani, Samir M.

    2017-08-01

    The reaction of Co(II), Cu(II), Zn(II), Cd(II) and Hg(II) with the synthesized N-(2-hydroxy-1-naphthylidene)-2-aminothiophenol Schiff base ligand (H2L) at room temperature resulted in the formation of the five complexes; [Co(HL)2]H2O, 1; [M(HL)2] (M = Cu, Zn and Cd), (2-4) and [Hg(HL)Cl], 5. The ligand and its complexes were characterized based on elemental analyses, IR, 1H NMR, magnetic measurement, molar conductance, and thermal analysis. Coats and Redfern method was used to compute the kinetic and thermodynamic parameters. Antimicrobial activities of H2L and its complexes have been studied. The binding of Co(II), Cu(II) and Zn(II) complexes to calf thymus DNA (CT-DNA) has been investigated using UV-Vis and fluorescence absorption spectra. The results indicated that the ligand and its complexes may bind to DNA by intercalation modes, with a much higher binding affinity of the complexes than that of the ligand. The equilibrium geometries of the studied complexes are investigated theoretically at the B3LYP/LANL2DZ level of theory, and it was found that these geometries are non-linear. The calculated EHOMO and ELUMO energies of the studied complexes can be used to calculate the global properties. The calculated nonlinear optical parameters (NLO); first order hyperpolarizibility (β) of the studied complexes show promising optical properties.

  14. Spectroscopic (FT-IR, FT-Raman, 1H, 13C NMR, UV/VIS), thermogravimetric and antimicrobial studies of Ca(II), Mn(II), Cu(II), Zn(II) and Cd(II) complexes of ferulic acid

    NASA Astrophysics Data System (ADS)

    Kalinowska, M.; Piekut, J.; Bruss, A.; Follet, C.; Sienkiewicz-Gromiuk, J.; Świsłocka, R.; Rzączyńska, Z.; Lewandowski, W.

    2014-03-01

    The molecular structure of Mn(II), Cu(II), Zn(II), Cd(II) and Ca(II) ferulates (4-hydroxy-3-methoxycinnamates) was studied. The selected metal ferulates were synthesized. Their composition was established by means of elementary and thermogravimetric analysis. The following spectroscopic methods were used: infrared (FT-IR), Raman (FT-Raman), nuclear magnetic resonance (13C, 1H NMR) and ultraviolet-visible (UV/VIS). On the basis of obtained results the electronic charge distribution in studied metal complexes in comparison with ferulic acid molecule was discussed. The microbiological study of ferulic acid and ferulates toward Escherichia coli, Bacillus subtilis, Candida albicans, Pseudomonas aeruginosa, Staphylococcus aureus and Proteus vulgaris was done.

  15. Spectroscopic (FT-IR, FT-Raman, 1H, 13C NMR, UV/VIS), thermogravimetric and antimicrobial studies of Ca(II), Mn(II), Cu(II), Zn(II) and Cd(II) complexes of ferulic acid.

    PubMed

    Kalinowska, M; Piekut, J; Bruss, A; Follet, C; Sienkiewicz-Gromiuk, J; Świsłocka, R; Rzączyńska, Z; Lewandowski, W

    2014-03-25

    The molecular structure of Mn(II), Cu(II), Zn(II), Cd(II) and Ca(II) ferulates (4-hydroxy-3-methoxycinnamates) was studied. The selected metal ferulates were synthesized. Their composition was established by means of elementary and thermogravimetric analysis. The following spectroscopic methods were used: infrared (FT-IR), Raman (FT-Raman), nuclear magnetic resonance ((13)C, (1)H NMR) and ultraviolet-visible (UV/VIS). On the basis of obtained results the electronic charge distribution in studied metal complexes in comparison with ferulic acid molecule was discussed. The microbiological study of ferulic acid and ferulates toward Escherichia coli, Bacillus subtilis, Candida albicans, Pseudomonas aeruginosa, Staphylococcus aureus and Proteus vulgaris was done. Copyright © 2013 Elsevier B.V. All rights reserved.

  16. Predicting outcomes in organophosphate poisoning based on APACHE II and modified APACHE II scores.

    PubMed

    Eizadi-Mood, N; Saghaei, M; Jabalameli, M

    2007-07-01

    The aim of this study was to evaluate the scores of the Acute Physiology and Chronic Health Evaluation (APACHE) II and a modified APACHE II system (MAS), without parameters of biochemical tests; and to find prognostic value of individual elements of the APACHE II and MAS in predicting outcomes in organophosphate (OP) poisoning. Data were collected from 131 patients. The median (25th-75th percentiles) of APACHE II score for survivors without intubation were found to be lower than those of non survivors or survivors with intubation and ventilation, [4 (1-7); versus 17.5 (7.8-29), and 13.5 (7.8-16.3)]. Logistic regression analysis identified white blood cell (WBC), potassium, Glasgow coma scale (GCS), age and sodium in APACHE II; GCS and mean arterial pressure in MAS system as prognostically valuable. There was no statistically significance difference between APACHE II and MAS scores in terms of area under Receiver Operating Characteristic Curve [(0.902, 95% confidence interval: (0.837-0.947) for APACHE II), and (0.892, 95% confidence interval: (0.826-0.940) for MAS); P=0.74) to predict need for intubation. It is concluded usage of MAS facilitates the prognostication of the OP poisoned patients due to simplicity, less time-consuming and effectiveness in an emergency situation.

  17. [Evaluation of serum PIVKA-II by Lumipulse PrestoII assay].

    PubMed

    Hiramatsu, Kumiko; Tanaka, Yasuhito; Takagi, Kazumi; Kani, Satomi; Goto, Takaaki; Takasaka, Yoshimitsu; Matsuura, Kentaro; Sugauchi, Fuminaka; Moriyama, Kazushige; Murakami, Hiroshi; Kitajima, Sachiko; Mizokami, Masashi

    2009-03-01

    Measurements of serum concentrations of Des-gamma-carboxy Prothrombin (PIVKA-II) are widely used for diagnosing hepatocellular carcinoma (HCC). Recently, in Lumipulsef assay, it was reported that antibodies against alkaline phosphatase (ALP) derived from anti bleeding sheets led false high values of PIVKA-II in the patients with HCC resection. To improve the previous issue, newly developed Lumipulse PrestoII assay was examined. (1) The assay was reliable and positively correlated with the previous assays (Lumipulse f and Picolumi, R = 0.997 and 0.994 (n=115), respectively). (2) Eleven cases, which had false high values of PIVKA-II by the Lumipulsef assay, were examined by the PrestoII assay with excess of inactive ALP. The false high values of 10 cases were improved, but only one was still high. False reactivity of this case was stronger than other cases, more effective adsorption was required. (3) Comparing the absorbent activity of inactive ALP among 6 different kinds, we found inactive ALP with much higher adsorbent activity. When this inactive ALP was applied to assay, false high values of PIVKA-II were improved in all 11 cases. In conclusion, the PrestoII assay, which applies the inactive ALP with high activity, is reliable and useful for clinical screening.

  18. Lifetimes and Oscillator Strengths for Ultraviolet Transitions in P II, Cl II and Cl III

    NASA Technical Reports Server (NTRS)

    Cheng, S.; Federman, S. R.; Schectman, R. M.; Brown, M.; Irving, R. E.; Fritts, M. C.; Gibson, N. D.

    2006-01-01

    Oscillator strengths for transitions in P II, Cl II and Cl III are derived from lifetimes and branching factions measured with beam-foil techniques. The focus is on the multiplets with a prominent interstellar line at 1153 A in P II which is seen in spectra of hot stars, and the lines at 1071 A in Cl II and 1011 A in Cl III whose lines are seen in spectra of diffuse interstellar clouds and the Io torus acquired with the Far Ultraviolet Spectroscopic Explorer. These data represent the first complete set of experimental f-values for the lines in the multiplets. Our results for P II (lambda)1153 agree well with Curtis semi-empirical predictions, as well as the large scale computations by Hibbert and by Tayal. The data for Cl II (lambda)1071 also agree very well with the most recent theoretical effort and with Morton s newest recommendations. For Cl III, however, our f-values are significantly larger than those given by Morton; instead, they are more consistent with recent large-scale theoretical calculations. Extensive tests provide confirmation that LS coupling rules apply to the transitions for the multiplets in Cl II and Cl III.

  19. Adsorption and desorption of Cu(II), Cd(II) and Pb(II) ions using chitosan crosslinked with epichlorohydrin-triphosphate as the adsorbent.

    PubMed

    Laus, Rogério; Costa, Thiago G; Szpoganicz, Bruno; Fávere, Valfredo T

    2010-11-15

    In this study, chitosan (CTS) was crosslinked with both epichlorohydrin (ECH) and triphosphate (TPP), by covalent and ionic crosslinking, respectively. The resulting new CTS-ECH-TPP adsorbent was characterized by CHN analysis, EDS, FTIR spectroscopy, TGA and DSC, and the adsorption and desorption of Cu(II), Cd(II) and Pb(II) ions in aqueous solution were investigated. Potentiometric studies were also performed and revealed three titratable protons for each pK(a) value of 5.14, 6.76 and 9.08. The results obtained showed that the optimum pH values for adsorption were 6.0 for Cu(II), 7.0 for Cd(II) and 5.0 for Pb(II). The kinetics study demonstrated that the adsorption process proceeded according to the pseudo-second-order model. Three isotherm models (Langmuir, Freundlich and Dubinin-Radushkevich) were employed in the analysis of the adsorption equilibrium data. The Langmuir model resulted in the best fit and the new adsorbent had maximum adsorption capacities for Cu(II), Cd(II) and Pb(II) ions of 130.72, 83.75 and 166.94 mg g(-1), respectively. Desorption studies revealed that HNO(3) and HCl were the best eluents for desorption of Cu(II), Cd(II) and Pb(II) ions from the crosslinked chitosan. Copyright © 2010 Elsevier B.V. All rights reserved.

  20. Coordination sphere vibrations in copper(II), nickel(II) and cobalt(II) complexes with 4-imidazoleacetic acid; metal isotope, deuteration, and density functional study.

    PubMed

    Drozdzewski, Piotr; Pawlak, Barbara

    2004-06-01

    Low-frequency vibrational spectra of Cu(II), Ni(II) and Co(II) complexes with 4-imidazoleacetic acid (HIA) are discussed. Metal isotope and deuteration effects were measured and used to assign the metal-ligand vibrations. These effects were included in density functional calculations carried out for the [Cu(IA)2] complex.

  1. STELLAR POPULATIONS AND THE STAR FORMATION HISTORIES OF LOW SURFACE BRIGHTNESS GALAXIES. II. H II REGIONS

    SciTech Connect

    Schombert, James; McGaugh, Stacy; Maciel, Tamela, E-mail: jschombe@uoregon.edu, E-mail: stacy.mcgaugh@case.edu, E-mail: tm419@cam.ac.uk

    2013-08-01

    The luminosities, colors, and H{alpha} emission for 429 H II regions in 54 low surface brightness (LSB) galaxies are presented. While the number of H II regions per galaxy is lower in LSB galaxies compared to star-forming irregulars and spirals, there is no indication that the size or luminosity function of H II regions differs from other galaxy types. The lower number of H II regions per galaxy is consistent with their lower total star formation rates. The fraction of the total L{sub H{alpha}} contributed by H II regions varies from 10% to 90% in LSB galaxies (the rest ofmore » the H{alpha} emission being associated with a diffuse component) with no correlation with galaxy stellar or gas mass. Bright H II regions have bluer colors, similar to the trend in spirals; their number and luminosities are consistent with the hypothesis that they are produced by the same H II luminosity function as spirals. Comparison with stellar population models indicates that the brightest H II regions in LSB galaxies range in cluster mass from a few 10{sup 3} M{sub Sun} (e.g., {rho} Oph) to globular-cluster-sized systems (e.g., 30 Dor) and that their ages are consistent with clusters from 2 to 15 Myr old. The faintest H II regions are comparable to those in the LMC powered by a single O or B star. Thus, star formation in LSB galaxies covers the full range of stellar cluster mass.« less

  2. The Bipolar II Depression Questionnaire: A Self-Report Tool for Detecting Bipolar II Depression

    PubMed Central

    Leung, Chi Ming; Yim, Chi Lap; Yan, Connie T. Y.; Chan, Cheuk Chi; Xiang, Yu-Tao; Mak, Arthur D. P.; Fok, Marcella Lei-Yee; Ungvari, Gabor S.

    2016-01-01

    Bipolar II (BP-II) depression is often misdiagnosed as unipolar (UP) depression, resulting in suboptimal treatment. Tools for differentiating between these two types of depression are lacking. This study aimed to develop a simple, self-report screening instrument to help distinguish BP-II depression from UP depressive disorder. A prototype BP-II depression questionnaire (BPIIDQ-P) was constructed following a literature review, panel discussions and a field trial. Consecutively assessed patients with a diagnosis of depressive disorder or BP with depressive episodes completed the BPIIDQ-P at a psychiatric outpatient clinic in Hong Kong between October and December 2013. Data were analyzed using discriminant analysis and logistic regression. Of the 298 subjects recruited, 65 (21.8%) were males and 233 (78.2%) females. There were 112 (37.6%) subjects with BP depression [BP-I = 42 (14.1%), BP-II = 70 (23.5%)] and 182 (62.4%) with UP depression. Based on family history, age at onset, postpartum depression, episodic course, attacks of anxiety, hypersomnia, social phobia and agoraphobia, the 8-item BPIIDQ-8 was constructed. The BPIIDQ-8 differentiated subjects with BP-II from those with UP depression with a sensitivity/specificity of 0.75/0.63 for the whole sample and 0.77/0.72 for a female subgroup with a history of childbirth. The BPIIDQ-8 can differentiate BP-II from UP depression at the secondary care level with satisfactory to good reliability and validity. It has good potential as a screening tool for BP-II depression in primary care settings. Recall bias, the relatively small sample size, and the high proportion of females in the BP-II sample limit the generalization of the results. PMID:26963908

  3. Dynamics of Spiral Arm Ionized Gas Observed in [N II] and [C II

    NASA Astrophysics Data System (ADS)

    Langer, William

    2015-10-01

    We propose to study the interaction of spiral arms with the highly ionized interarm gas; the resulting compression and conversion of this diffuse gas is a fundamental and initial step in the formation of dense clouds and ultimately star formation in spiral galaxies. We will observe two important tracers of ionized gas, the far-infrared spectral lines of [C II] and [N II], which can delineate the distribution of ionized gas components. Two key results from a Herschel HIFI [C II] survey include the delineation of the structure of spiral arm lanes in [C II], HI and CO gas tracers, including the detection of a compressed WIM in [C II] on the leading edge of spiral arms, and the vertical scale height of [C II] versus HI and CO. A limited Herschel HIFI [N II] survey revealed surprisingly strong and widespread emission in the arms. We propose using the SOFIA/GREAT instrument to make a cross-scan map in [N II] and [C II] along the Scutum-Crux spiral arm tangency at l=30(o) , to study the dynamics of the low density ionized gas entering the spiral arm and within the spiral arms, with respect to atomic and molecular gas. The spiral arm tangencies offer a long path length over a relatively narrow velocity interval, allowing detection of low emissivity lines, and the Scutum-Crux arm is observable by SOFIA from the Northern Hemisphere. A cross-scan in b at l=30(o) will delineate the vertical distribution of ionized gas. We will use these data to understand the forces and pressures that determine the vertical distribution of gas in the disk and the interaction of spiral arm potentials in compressing the ionized interarm gas, which is the first stage of forming the neutral dense clouds in the arms.

  4. THE GREEN BANK TELESCOPE H II REGION DISCOVERY SURVEY. II. THE SOURCE CATALOG

    SciTech Connect

    Anderson, L. D.; Bania, T. M.; Balser, Dana S.

    2011-06-01

    The Green Bank Telescope (GBT) H II Region Discovery Survey has doubled the number of known H II regions in the Galactic zone 343{sup 0} {<=} l {<=} 67{sup 0} with | b | {<=} 1{sup 0}. We detected 603 discrete hydrogen radio recombination line (RRL) components at 9 GHz (3 cm) from 448 targets. Our targets were selected based on spatially coincident mid-infrared and 20 cm radio continuum emission. Such sources are almost invariably H II regions; we detected hydrogen RRL emission from 95% of our target sample. The sensitivity of the GBT and the power of its spectrometermore » together made this survey possible. Here, we provide a catalog of the measured properties of the RRL and continuum emission from the survey nebulae. The derived survey completeness limit, 180 mJy at 9 GHz, is sufficient to detect all H II regions ionized by single O-stars to a distance of 12 kpc. These recently discovered nebulae share the same distribution on the sky as does the previously known census of Galactic H II regions. On average, however, the new nebulae have fainter continuum fluxes, smaller continuum angular sizes, fainter RRL intensities, and smaller RRL line widths. Though small in angular size, many of our new nebulae show little spatial correlation with tracers associated with extremely young H II regions, implying that our sample spans a range of evolutionary states. We discovered 34 first quadrant negative-velocity H II regions, which lie at extreme distances from the Sun and appear to be part of the Outer Arm. We found RRL emission from 208 Spitzer GLIMPSE 8.0 {mu}m 'bubble' sources, 65 of which have been cataloged previously. It thus appears that nearly all GLIMPSE bubbles are H II regions and that {approx}50% of all Galactic H II regions have a bubble morphology at 8.0 {mu}m.« less

  5. Report of Programme Commission II (Natural Sciences).

    ERIC Educational Resources Information Center

    United Nations Educational, Scientific, and Cultural Organization, Paris (France). General Conference.

    As the first part of the report of the Programme Commission II, a summary of discussions on plans for natural sciences and their applications is presented in this document. The two agenda items are: (1) detailed consideration of the 1973-74 draft program and budget and of the 1973-78 draft medium-term outline, and (2) desirability of adopting an…

  6. Ir Spectroscopy and Nickel (II) Hexammines

    ERIC Educational Resources Information Center

    Reedijk, J.; And Others

    1975-01-01

    Describes an experiment, for the general chemistry laboratory, intended to introduce the student to infrared spectroscopy. After being introduced to the theory of molecular vibrations on an elementary level, each student receives a list of 5-7 nickel (II) ammines to be prepared, analyzed and characterized by infrared spectoscopy. (MLH)

  7. Occupational Information 1990/91. Volume II.

    ERIC Educational Resources Information Center

    Nebraska Univ., Lincoln. Nebraska Career Information System.

    The Nebraska Occupational Information books (volumes I and II) contain information about 386 different occupations in the state and answer questions about specific occupations in detail. The descriptions are arranged according to a U.S. Department of Labor classification system, with occupational titles clustered in general groups of selected…

  8. EBR-II fuel slug casting experience

    SciTech Connect

    Wilkes, C. W.; Batte`, G. L.; Tracy, D. B.

    1987-07-01

    The following paper presents a chronology of EBR-II fuel slug casting experience. Starting with the early vendor campaigns, the paper explains how production of EBR-II fuel, as well as fuel for off-site reactors, has evolved. The production facilities (i.e., EFL, Room 20, FMF, etc.) and casting techniques are discussed in detail. The paper also presents how the original casting operations have improved and the problems encountered as the techniques were developed. Extensive descriptions and data are given on the major experimental programs currently ongoing at EBR-II. Major programs include the IFR lead subassemblies, large diameter slugs, IFR metal fuel RBCB,more » and the FFTF subassembly program. Concluding the paper is a brief description of future development projects being considered and a summation of how EBR-II Fuels and Materials has been able to overcome various administration obstacles (i.e., improved security and safeguards measures) to continue to meet the increasing demands of fuel production while maintaining an aggressive and active research and development program in fuel slug production.« less

  9. African Americans and World War II.

    ERIC Educational Resources Information Center

    Kersten, Andrew E.

    2002-01-01

    Focuses on the experience of African Americans during World War II on the homefront and in the armed forces. States that African Americans not only fought fascism overseas but also apartheid in the United States, also known as the "Double V." (CMK)

  10. Leveraging Information Technology. Track II: Innovative Management.

    ERIC Educational Resources Information Center

    CAUSE, Boulder, CO.

    Seven papers from the 1987 CAUSE conference's Track II, Innovative Management, are presented. They include: "Is This Creative, or What!" (Kenneth C. Blythe); "Joint Application Design: Can a User Committee Design a System in Four Days?" (Diane Kent, David Smithers); "Making It Happen without Appropriation" (Robert E.…

  11. Are coronal type II shocks piston driven?

    NASA Technical Reports Server (NTRS)

    Gopalswamy, N.; Kundu, M. R.

    1992-01-01

    Flare blast waves and shocks piston driven by coronal mass ejections (CMEs) have been proposed to be responsible for generating type II radio bursts in the solar corona. The idea for piston-driven shocks came primarily from temporal association of shocks and CMEs. Our compilation of CME events with simultaneous radio observations with positional information supports idea of flare blast waves.

  12. Project Final Report: HPC-Colony II

    SciTech Connect

    Jones, Terry R; Kale, Laxmikant V; Moreira, Jose

    2013-11-01

    This report recounts the HPC Colony II Project which was a computer science effort funded by DOE's Advanced Scientific Computing Research office. The project included researchers from ORNL, IBM, and the University of Illinois at Urbana-Champaign. The topic of the effort was adaptive system software for extreme scale parallel machines. A description of findings is included.

  13. Metalloantibiotics: synthesis, characterization and in-vitro antibacterial studies on cobalt (II), copper (II), nickel (II) and zinc (II) complexes with cloxacillin.

    PubMed

    Chohan, Zahid H; Supuran, Claudiu T

    2006-08-01

    The synthesis and characterization of cloxacillin (clox) complexes with divalent metal ions [Co (II), Cu (II), Ni (II) and Zn (II)] is described. The nature of bonding of the chelated cloxacillin and the structures of the metal complexes have been elucidated on the basis of their physical and spectroscopic data. In all the complexes, the cloxacillin acts as a uninegatively charged bidentate ligand with coordination involving the carboxylate-O and endocyclic-N of the beta-lactam ring. The new compounds have been screened for in-vitro antibacterial activity against Escherichia coli (a), Klebsiella pneumonae (b), Proteus mirabilis (c), Pseudomonas aeruginosa (d), Salmonella typhi (e), Shigella dysentriae (f), Bacillus cereus (g), Corynebacterium diphtheriae (h), Staphylococcus aureus (j) and Streptococcus pyogenes (k) bacterial strains. The brine shrimp bioassay was also carried out to study their in-vitro cytotoxic properties. All compounds, respectively, showed a promising activity (90%) against five bacterial species at 10 microg/ml concentration and a significant activity (52%) against the same test bacteria at 25 microg/ml concentration.

  14. II Zw 40 - 30 Doradus on Steroids

    NASA Astrophysics Data System (ADS)

    Leitherer, Claus; Lee, Janice C.; Levesque, Emily M.

    2017-11-01

    We obtained HST COS G140L spectra of the enigmatic nearby blue compact dwarf galaxy II Zw 40. The galaxy hosts a nuclear super star cluster embedded in a radio-bright nebula, similar to those observed in the related blue compact dwarfs NGC 5253 and Henize 2-10. The ultraviolet spectrum of II Zw 40 is exceptional in terms of the strength of He II 1640, O III] 1666 and C III] 1909. We determined reddening, age, and the cluster mass from the ultraviolet data. The super nebula and the ionizing cluster exceed the ionizing luminosity and stellar mass of the local benchmark 30 Doradus by an order of magnitude. Comparison with stellar evolution models accounting for rotation reveals serious short-comings: these models do not account for the presence of Wolf-Rayet-like stars at young ages observed in II Zw 40. Photoionization modeling is used to probe the origin of the nebular lines and determine gas phase abundances. C/O is solar, in agreement with the result of the stellar-wind modeling.

  15. SAGE II Version 7.00 Release

    Atmospheric Science Data Center

    2013-07-10

    ... algorithms from SAGE III v4.00 Ceased removal of the water vapor extinction in the 600nm channel due to uncertainty in the H2O ... Updated our estimation of the SAGE II water vapor channel filter location drift resulting in better agreement with more modern datasets ...

  16. Arsenal Workers During World War II

    NASA Technical Reports Server (NTRS)

    1945-01-01

    During World War II, Arsenal workers from Huntsville, Alabama. and surrounding areas responded to the call for civilian defense workers. This February 20, 1945 photo shows workers filling colored smoke grenades that were used for signaling. (Courtesy of Huntsville/Madison County Public Library)

  17. Circuit II--A Conversational Graphical Interface.

    ERIC Educational Resources Information Center

    Singer, Ronald A.

    1993-01-01

    Provides an overview of Circuit II, an interactive system that provides users with a graphical representation of an electronic circuit within which questions may be posed and manipulated, and discusses how mouse selections have analogous roles to certain natural language features, such as anaphora, deixis, and ellipsis. (13 references) (EA)

  18. The Uptake Mechanism of Cd(II), Cr(VI), Cu(II), Pb(II), and Zn(II) by Mycelia and Fruiting Bodies of Galerina vittiformis

    PubMed Central

    Damodaran, Dilna; Balakrishnan, Raj Mohan; Shetty, Vidya K.

    2013-01-01

    Optimum concentrations of heavy metals like copper, cadmium, lead, chromium, and zinc in soil are essential in carrying out various cellular activities in minimum concentrations and hence help in sustaining all life forms, although higher concentration of these metals is lethal to most of the life forms. Galerina vittiformis, a macrofungus, was found to accumulate these heavy metals into its fleshy fruiting body in the order Pb(II) > Cd(II) > Cu(II) > Zn(II) > Cr(VI) from 50 mg/kg soil. It possesses various ranges of potential cellular mechanisms that may be involved in detoxification of heavy metals and thus increases its tolerance to heavy metal stress, mainly by producing organic acids and phytochelatins (PCs). These components help in repairing stress damaged proteins and compartmentalisation of metals to vacuoles. The stress tolerance mechanism can be deduced by various analytical tools like SEM-EDX, FTIR, and LC-MS. Production of two kinds of phytochelatins was observed in the organism in response to metal stress. PMID:24455671

  19. Plasma Filled Diode Experiments on Gamble II

    DTIC Science & Technology

    1993-06-01

    on Gamble II shots is shown in Fig. 4. The diode impedance is plotted for different (assumed) densities, corresponding to the 3 - -+- Shot #5245 M ...Conf. on Plasma Science (Williamsburg 1991) p. 164. 3P.J. Goodrich, R.C. Fisher, D.O. Hinshelwood, J.R. Soller, R.J. Commisso , and B.V. Weber, in Proc

  20. An ADC Interface for the Apple II.

    ERIC Educational Resources Information Center

    Leiker, P. Steven

    1990-01-01

    Described is the construction of a simple analog-to-digital convertor circuit to interface an Apple II+ microcomputer to a light sensor used in conjunction with a holographic gear inspector. A list of parts, circuit diagram, and a simple BASIC program for the convertor are provided. (CW)

  1. Class II malocclusion occlusal severity description

    PubMed Central

    JANSON, Guilherme; SATHLER, Renata; FERNANDES, Thais Maria Freire; ZANDA, Marcelo; PINZAN, Arnaldo

    2010-01-01

    Objectives It is well known that the efficacy and the efficiency of a Class II malocclusion treatment are aspects closely related to the severity of the dental anteroposterior discrepancy. Even though, sample selection based on cephalometric variables without considering the severity of the occlusal anteroposterior discrepancy is still common in current papers. In some of them, when occlusal parameters are chosen, the severity is often neglected. The purpose of this study is to verify the importance given to the classification of Class II malocclusion, based on the criteria used for sample selection in a great number of papers published in the orthodontic journal with the highest impact factor. Material and Methods A search was performed in PubMed database for full-text research papers referencing Class II malocclusion in the history of the American Journal of Orthodontics and Dentofacial Orthopedics (AJO-DO). Results A total of 359 papers were retrieved, among which only 72 (20.06%) papers described the occlusal severity of the Class II malocclusion sample. In the other 287 (79.94%) papers that did not specify the anteroposterior discrepancy severity, description was considered to be crucial in 159 (55.40%) of them. Conclusions Omission in describing the occlusal severity demands a cautious interpretation of 44.29% of the papers retrieved in this study. PMID:20835576

  2. Internet Image Viewer (iiV)

    PubMed Central

    Lee, Joel T; Munch, Kristin R; Carlis, John V; Pardo, José V

    2008-01-01

    Background Visualizing 3-dimensional (3-D) datasets is an important part of modern neuroimaging research. Many tools address this problem; however, they often fail to address specific needs and flexibility, such as the ability to work with different data formats, to control how and what data are displayed, to interact with values, and to undo mistakes. Results iiV, an interactive software program for displaying 3-D brain images, is described. This tool was programmed to solve basic problems in 3-D data visualization. It is written in Java so it is extensible, is platform independent, and can display images within web pages. iiV displays 3-D images as 2-dimensional (2-D) slices with each slice being an independent object with independent features such as location, zoom, colors, labels, etc. Feature manipulation becomes easier by having a full set of editing capabilities including the following: undo or redo changes; drag, copy, delete and paste objects; and save objects with their features to a file for future editing. It can read multiple standard positron emission tomography (PET) and magnetic resonance imaging (MRI) file formats like ECAT, ECAT7, ANALYZE, NIfTI-1 and DICOM. We present sample applications to illustrate some of the features and capabilities. Conclusion iiV is an image display tool with many useful features. It is highly extensible, platform independent, and web-compatible. This report summarizes its features and applications, while illustrating iiV's usefulness to the biomedical imaging community. PMID:18510765

  3. Fiber, Fabric and Fashion. Environment II.

    ERIC Educational Resources Information Center

    Arizona State Univ., Tempe.

    A competency-based instructional guide for grades 7-14, this volume is one of three parts, each of which focuses on a different environment (psychomotor, cognitive, or affective), and each of which includes competencies and learning activities for each of three instructional levels. The topics for this volume (Environment II--cognitive) are…

  4. Community Living Skills Guide: Money Management II.

    ERIC Educational Resources Information Center

    Kreps, Alice Roelofs; Black, Jan

    One of twenty course guides in the Community Living Skills Guide for the College for Living series, this document provides guidelines and workbook activities for the course, Money Management II (Checkbooks, Budgets, and Survival Math.) The series of courses for developmentally disabled adults is intended to supplement residential programs and to…

  5. Motivations for speeding : Volume II : findings report.

    DOT National Transportation Integrated Search

    2013-09-01

    This is Volume II of a three-volume report. It contains the results of a study that examined the speeding behavior of drivers in their own vehicles over the course of three to four weeks of naturalistic driving in urban (Seattle, WA) and rural (Colle...

  6. Cu(II) promotes amyloid pore formation

    SciTech Connect

    Zhang, Hangyu, E-mail: hangyuz@uw.edu; Rochet, Jean-Christophe; Stanciu, Lia A.

    2015-08-14

    The aggregation of α-synuclein is associated with dopamine neuron death in Parkinson's disease. There is controversy in the field over the question of which species of the aggregates, fibrils or protofibrils, are toxic. Moreover, compelling evidence suggested the exposure to heavy metals to be a risk of PD. Nevertheless, the mechanism of metal ions in promoting PD remains unclear. In this research, we investigated the structural basis of Cu(II) induced aggregation of α-synuclein. Using transmission electron microscopy experiments, Cu(II) was found to promote in vitro aggregation of α-synuclein by facilitating annular protofibril formation rather than fibril formation. Furthermore, neuroprotective baicalein disaggregatedmore » annular protofibrils accompanied by considerable decrease of β-sheet content. These results strongly support the hypothesis that annular protofibrils are the toxic species, rather than fibrils, thereby inspiring us to search novel therapeutic strategies for the suppression of the toxic annular protofibril formation. - Highlights: • Cu(II) promoted the annular protofibril formation of α-synuclein in vitro. • Cu(II) postponed the in vitro fibrillization of α-synuclein. • Neuroprotective baicalein disaggregated annular protofibrils.« less

  7. The Ned IIS project - forest ecosystem management

    Treesearch

    W. Potter; D. Nute; J. Wang; F. Maier; Michael Twery; H. Michael Rauscher; P. Knopp; S. Thomasma; M. Dass; H. Uchiyama

    2002-01-01

    For many years we have held to the notion that an Intelligent Information System (IIS) is composed of a unified knowledge base, database, and model base. The main idea behind this notion is the transparent processing of user queries. The system is responsible for "deciding" which information sources to access in order to fulfil a query regardless of whether...

  8. Molecular Medicine II: Hormone Dependent Cancers

    DTIC Science & Technology

    2005-04-01

    family, member 4 deiodinase, iodothyronine, -3.1 Dio2 thyroid hormone catabolism type II serne (cysteine) -4.3 Serpina3n proteinas inhibitor, clade A...ElO, and the anti- p44/42 teins and recruit various proteinases , including matrix metal- MAPK rabbit polyclonal antibody were from Cell Signaling Tech

  9. World War II Informational Fact Sheets.

    ERIC Educational Resources Information Center

    Department of Defense, Washington, DC.

    This commemorative book provides numerous fact sheets on various aspects of World War II, both on the fighting front and the homefront. Replicas of posters of the war era, descriptions of battles with maps, contributions of women and minorities to the war effort, even music of the wartime era, add to this collection of resource materials useful to…

  10. A Camp Director Remembers World War II.

    ERIC Educational Resources Information Center

    Cohen, Helen Herz

    2003-01-01

    A girl's camp in Maine during World War II had to deal with food rationing and black-market food dealers. Campers picked beans to raise money for refugees, sewed clothes for refugees, and spotted for enemy planes from Mt. Pleasant. An attempt to use a horse-drawn cart for transportation failed, and good help was hard to find. (TD)

  11. Unlearning Established Organizational Routines--Part II

    ERIC Educational Resources Information Center

    Fiol, C. Marlena; O'Connor, Edward J.

    2017-01-01

    Purpose: The purpose of Part II of this two-part paper is to uncover important differences in the nature of the three unlearning subprocesses, which call for different leadership interventions to motivate people to move through them. Design/methodology/approach: The paper draws on research in behavioral medicine and psychology to demonstrate that…

  12. VELOCITY-RESOLVED [C ii] EMISSION AND [C ii]/FIR MAPPING ALONG ORION WITH HERSCHEL.

    PubMed

    Goicoechea, Javier R; Teyssier, D; Etxaluze, M; Goldsmith, P F; Ossenkopf, V; Gerin, M; Bergin, E A; Black, J H; Cernicharo, J; Cuadrado, S; Encrenaz, P; Falgarone, E; Fuente, A; Hacar, A; Lis, D C; Marcelino, N; Melnick, G J; Müller, H S P; Persson, C; Pety, J; Röllig, M; Schilke, P; Simon, R; Snell, R L; Stutzki, J

    2015-10-10

    We present the first ~7.5'×11.5' velocity-resolved (~0.2 km s -1 ) map of the [C ii] 158 μ m line toward the Orion molecular cloud 1 (OMC 1) taken with the Herschel /HIFI instrument. In combination with far-infrared (FIR) photometric images and velocity-resolved maps of the H41 α hydrogen recombination and CO J =2-1 lines, this data set provides an unprecedented view of the intricate small-scale kinematics of the ionized/PDR/molecular gas interfaces and of the radiative feedback from massive stars. The main contribution to the [C ii] luminosity (~85 %) is from the extended, FUV-illuminated face of the cloud ( G 0 >500, n H >5×10 3 cm -3 ) and from dense PDRs ( G ≳10 4 , n H ≳10 5 cm -3 ) at the interface between OMC 1 and the H ii region surrounding the Trapezium cluster. Around ~15 % of the [C ii] emission arises from a different gas component without CO counterpart. The [C ii] excitation, PDR gas turbulence, line opacity (from [ 13 C ii]) and role of the geometry of the illuminating stars with respect to the cloud are investigated. We construct maps of the L [C ii]/ L FIR and L FIR / M Gas ratios and show that L [C ii]/ L FIR decreases from the extended cloud component (~10 -2 -10 -3 ) to the more opaque star-forming cores (~10 -3 -10 -4 ). The lowest values are reminiscent of the "[C ii] deficit" seen in local ultra-luminous IR galaxies hosting vigorous star formation. Spatial correlation analysis shows that the decreasing L [C ii]/ L FIR ratio correlates better with the column density of dust through the molecular cloud than with L FIR / M Gas . We conclude that the [C ii] emitting column relative to the total dust column along each line of sight is responsible for the observed L [C ii]/ L FIR variations through the cloud.

  13. VELOCITY-RESOLVED [C ii] EMISSION AND [C ii]/FIR MAPPING ALONG ORION WITH HERSCHEL *,**

    PubMed Central

    Goicoechea, Javier R.; Teyssier, D.; Etxaluze, M.; Goldsmith, P.F.; Ossenkopf, V.; Gerin, M.; Bergin, E.A.; Black, J.H.; Cernicharo, J.; Cuadrado, S.; Encrenaz, P.; Falgarone, E.; Fuente, A.; Hacar, A.; Lis, D.C.; Marcelino, N.; Melnick, G.J.; Müller, H.S.P.; Persson, C.; Pety, J.; Röllig, M.; Schilke, P.; Simon, R.; Snell, R.L.; Stutzki, J.

    2015-01-01

    We present the first ~7.5′×11.5′ velocity-resolved (~0.2 km s−1) map of the [C ii] 158 μm line toward the Orion molecular cloud 1 (OMC 1) taken with the Herschel/HIFI instrument. In combination with far-infrared (FIR) photometric images and velocity-resolved maps of the H41α hydrogen recombination and CO J=2-1 lines, this data set provides an unprecedented view of the intricate small-scale kinematics of the ionized/PDR/molecular gas interfaces and of the radiative feedback from massive stars. The main contribution to the [C ii] luminosity (~85 %) is from the extended, FUV-illuminated face of the cloud (G0>500, nH>5×103 cm−3) and from dense PDRs (G≳104, nH≳105 cm−3) at the interface between OMC 1 and the H ii region surrounding the Trapezium cluster. Around ~15 % of the [C ii] emission arises from a different gas component without CO counterpart. The [C ii] excitation, PDR gas turbulence, line opacity (from [13C ii]) and role of the geometry of the illuminating stars with respect to the cloud are investigated. We construct maps of the L[C ii]/LFIR and LFIR/MGas ratios and show that L[C ii]/LFIR decreases from the extended cloud component (~10−2–10−3) to the more opaque star-forming cores (~10−3–10−4). The lowest values are reminiscent of the “[C ii] deficit” seen in local ultra-luminous IR galaxies hosting vigorous star formation. Spatial correlation analysis shows that the decreasing L[C ii]/LFIR ratio correlates better with the column density of dust through the molecular cloud than with LFIR/MGas. We conclude that the [C ii] emitting column relative to the total dust column along each line of sight is responsible for the observed L[C ii]/LFIR variations through the cloud. PMID:26568638

  14. AIM-9X Block II Sidewinder (AIM-9X Blk II)

    DTIC Science & Technology

    2015-12-01

    Selected Acquisition Report ( SAR ) RCS: DD-A&T(Q&A)823-442 AIM-9X Block II Sidewinder (AIM-9X Blk II) As of FY 2017 President’s Budget Defense...Acquisition Management Information Retrieval (DAMIR) March 23, 2016 15:14:10 UNCLASSIFIED AIM-9X Blk II December 2015 SAR March 23, 2016 15:14:10... SAR March 23, 2016 15:14:10 UNCLASSIFIED 3 PB - President’s Budget PE - Program Element PEO - Program Executive Officer PM - Program Manager POE

  15. Trident II (D-5) Sea Launched Ballistic Missile UGM 133A (Trident II Missile)

    DTIC Science & Technology

    2015-12-01

    Selected Acquisition Report ( SAR ) RCS: DD-A&T(Q&A)823-178 Trident II (D-5) Sea-Launched Ballistic Missile UGM 133A (Trident II Missile) As of FY...December 2015 SAR March 17, 2016 12:10:33 UNCLASSIFIED 2 Table of Contents Common Acronyms and Abbreviations for MDAP Programs 3 Program...Acquisition Unit Cost Trident II Missile December 2015 SAR March 17, 2016 12:10:33 UNCLASSIFIED 3 PB - President’s Budget PE - Program Element PEO - Program

  16. Arginase II inhibition prevents nitrate tolerance

    PubMed Central

    Khong, SML; Andrews, KL; Huynh, NN; Venardos, K; Aprico, A; Michell, DL; Zarei, M; Moe, KT; Dusting, GJ; Kaye, DM; Chin-Dusting, JPF

    2012-01-01

    BACKGROUND AND PURPOSE Nitrate tolerance, the loss of vascular responsiveness with continued use of nitrates, remains incompletely understood and is a limitation of these therapeutic agents. Vascular superoxide, generated by uncoupled endothelial NOS (eNOS), may play a role. As arginase competes with eNOS for L-arginine and may exacerbate the production of reactive oxygen species (ROS), we hypothesized that arginase inhibition might reduce nitrate tolerance. EXPERIMENTAL APPROACH Vasodilator responses were measured in aorta from C57Bl/6 and arginase II knockout (argII –/–) mice using myography. Uncoupling of eNOS, determined as eNOS monomer : dimer ratio, was assessed using low-temperature SDS-PAGE and ROS levels were measured using L-012 and lucigenin-enhanced chemiluminescence. KEY RESULTS Repeated application of glyceryl trinitrate (GTN) on aorta isolated from C57Bl/6 mice produced a 32-fold rightward shift of the concentration–response curve. However this rightward shift (or resultant tolerance) was not observed in the presence of the arginase inhibitor (s)-(2-boronethyl)-L-cysteine HCl (BEC; 100 µM) nor in aorta isolated from argII –/– mice. Similar findings were obtained after inducing nitrate tolerance in vivo. Repeated administration of GTN in human umbilical vein endothelial cells induced uncoupling of eNOS from its dimeric state and increased ROS levels, which were reduced with arginase inhibition and exogenous L-arginine. Aortae from GTN tolerant C57Bl/6 mice exhibited increased arginase activity and ROS production, whereas vessels from argII –/– mice did not. CONCLUSION AND IMPLICATIONS Arginase II removal prevents nitrate tolerance. This may be due to decreased uncoupling of eNOS and consequent ROS production. PMID:22288373

  17. Dust Production in Type II SNe

    NASA Astrophysics Data System (ADS)

    Andrews, Jennifer; Barlow, Mike; Clayton, Geoffrey; Ercolano, Barbara; Gordon, Karl; Meixner, Margaret; Sugerman, Ben; Welch, Doug

    2008-03-01

    Recent detection of large amounts of dust in high redshift galaxies has led to an increased interest in the importance of Type II supernovae (SNe) as dust producers. The dust in high-z galaxies must come from young, massive stars, so Type II SNe are one of the few possible sources. We propose to observe three very bright Type II SNe (SN 2007it, 2007oc and 2007od) in nearby galaxies. The ages of these SNe mean that they will be perfectly timed to be in their dust formation phases during Cycle 5. Three observational signatures of this dust formation can be seen, a decrease in the continuum brightness in the visible, a developing infrared excess, and asymmetric, blue-shifted emission-line profiles. We are already planning photometric and spectroscopic observations of these SNe with Gemini and SMARTS, but observations of the IR emission are needed to confirm that dust formation has occurred. These three indicators usually appear around 300-600 days after the SN explosion, when the brightness of the SN has diminished considerably. Fortunately, these three SNe are all unusually bright, allowing us a rare opportunity to follow them through and beyond their dust formation phases. With Spitzer, we will be able to carefully study the IR emission, and together with the Gemini and SMARTS data, we may be able to double the number of Type II SNe known to have shown all three dust formation signatures. This increased sample size will help answer what fraction of Type II SNe produce dust, how much dust they produce, and what conditions of the SNe ejecta affect the dust formation. These estimates will put strong constraints on the formation of dust seen in young, high redshift galaxies.

  18. Zn(II) ions Substantially Perturb Cu(II) ion Coordination in Amyloid-β at Physiological pH

    PubMed Central

    Silva, K. Ishara; Saxena, Sunil

    2013-01-01

    The interaction of Cu(II) and Zn(II) ions with Amyloid-β (Aβ) plays an important role in the etiology of Alzheimer’s disease. We describe the use of electron spin resonance (ESR) to measure metal binding competition between Cu(II) and Zn(II) in Amyloid-β at physiological pH. Continuous wave (CW) ESR show that Cu(II) has a significantly higher affinity towards Aβ(1–16) than Zn(II) at physiological pH. Importantly, of the two known Cu(II) coordination modes in Aβ, component I and component II, Zn(II) displaces Cu(II) only from component I. Our results indicate that at excess amounts of Zn(II) component II becomes the most dominant coordination mode. This observation is important as Aβ aggregates in the brain contain a high Zn(II) ion concentration. In order to determine details of the metal ion competition, ESEEM experiments were carried out on Aβ variants that were systematically 15N labeled. In the presence of Zn(II), most peptides use His 14 as an equatorial ligand to bind Cu(II) ions. Interestingly, Zn(II) ions completely substitute Cu(II) ions that are simultaneously coordinated to His6 and His13. Furthermore, in the presence of Zn(II), the proportion of Cu(II) ions that are simultaneously coordinated to His 13 and His 14 is increased. Based on our results we suggest that His 13 plays a critical role in modulating the morphology of Aβ aggregates. PMID:23841511

  19. Synthesis and characterization of VO(II), Co(II), Ni(II), Cu(II) and Zn(II) complexes of chromone based azo-linked Schiff base ligand

    NASA Astrophysics Data System (ADS)

    Anitha, C.; Sheela, C. D.; Tharmaraj, P.; Johnson Raja, S.

    2012-12-01

    Azo-Schiff-base complexes of VO(II), Co(II), Ni(II), Cu(II) and Zn(II) have been synthesized and characterized by elemental analysis, IR, UV-Vis, 1H NMR, mass spectra, molar conductance, magnetic susceptibility measurement, electron spin resonance (EPR), CV, fluorescence, NLO and SEM. The conductance data indicate the nonelectrolytic nature of the complexes, except VO(II) complex which is electrolytic in nature. On the basis of electronic spectra and magnetic susceptibility octahedral geometry has been proposed for the complexes. The EPR spectra of copper and oxovanadium complexes in DMSO at 300 and 77 K were recorded and its salient features are reported. The redox behavior of the copper(II) complex was studied using cyclic voltammetry. The in vitro antimicrobial activity against Staphylococcus aureus, Escherichia coli, Salmonella enterica typhi, Bacillus subtilis and Candida strains was studied and compared with that of free ligand by well-diffusion technique. The azo Schiff base exhibited fluorescence properties originating from intraligand (π-π∗) transitions and metal-mediated enhancement is observed on complexation and so the synthesized complexes can serve as potential photoactive materials as indicated from their characteristic fluorescence properties. On the basis of the optimized structures, the second-order nonlinear optical properties (NLO) are calculated by using second-harmonic generation (SHG) and also the surface morphology of the complexes was studied by SEM.

  20. The ultraviolet IUE spectrum of the population II horizontal-branch A star HD 109995

    NASA Technical Reports Server (NTRS)

    Adelman, S. J.; Leckrone, D. S.

    1986-01-01

    Eight SWP and six LWP high dispersion IUE images of the field horizontal-branch A star HD 109995 have been averaged to increase the signal-to-noise ratio. The line density in the UV is greater than that of the optical region, but less than that of comparable population I A stars. Many of the identified lines are those of Fe II. Lines of C I, C II, N I, O I, Mg I, Mg II, Al II, Al III, Si I, Si II, P II, S I, Cl I, Ti II, V II, Cr II, Mn II, Fe I, Co II, Ni II, Zn II, and Ge II are also present. Definite interstellar lines of C II, Mg I, Mg II, Al II, Si II, and Fe II were found.

  1. Validation and refinement of mixture volumetric material properties identified in superpave monitoring project II : phase II.

    DOT National Transportation Integrated Search

    2015-02-01

    This study was initiated to validate and refine mixture volumetric material properties identified in the : Superpave Monitoring Project II. It has been found that differences in performance are primarily controlled : by differences in gradation and r...

  2. Biochemical and Spectroscopic Observation of Mn(II) Sequestration from Bacterial Mn(II) Transport Machinery by Calprotectin.

    PubMed

    Hadley, Rose C; Gagnon, Derek M; Brophy, Megan Brunjes; Gu, Yu; Nakashige, Toshiki G; Britt, R David; Nolan, Elizabeth M

    2018-01-10

    Human calprotectin (CP, S100A8/S100A9 oligomer) is a metal-sequestering host-defense protein that prevents bacterial acquisition of Mn(II). In this work, we investigate Mn(II) competition between CP and two solute-binding proteins that Staphylococcus aureus and Streptococcus pneumoniae, Gram-positive bacterial pathogens of significant clinical concern, use to obtain Mn(II) when infecting a host. Biochemical and electron paramagnetic resonance (EPR) spectroscopic analyses demonstrate that CP outcompetes staphylococcal MntC and streptococcal PsaA for Mn(II). This behavior requires the presence of excess Ca(II) ions, which enhance the Mn(II) affinity of CP. This report presents new spectroscopic evaluation of two Mn(II) proteins important for bacterial pathogenesis, direct observation of Mn(II) sequestration from bacterial Mn(II) acquisition proteins by CP, and molecular insight into the extracellular battle for metal nutrients that occurs during infection.

  3. Stability constants of Ni(II)- and Cu(II)-N-heterocycle complexes according to spectrophotometric data

    NASA Astrophysics Data System (ADS)

    Badhe, Samata; Tekade, Pradip; Bajaj, Sonal; Thakare, Shrikant

    2015-12-01

    The interaction of Ni(II) and Cu(II) with ethyl 4-(4-hydroxyphenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine- 5-carboxylate [Ligand 1], 4-(1H-benzimidazol-2-yl)phenol [Ligand 2], and 2-(3-phenylamino- 4,5-dihydro-1,2-oxazol-5-yl)phenol [Ligand 3] have been studied by spectrophotometric technique at 0.01 M ionic strength and 28°C in 70% dioxane—water mixture. The data obtained were used to estimate the stability constant of these ligands. Spectrophotometric investigation of Ni(II) and Cu(II) complexes with these ligands shows 1: 1 complex formation. The formation of complexes has been studied by Job's variation method. The values of conditional stability constants of Cu(II) complexes are greater than the corresponding Ni(II) complexes. The greater value of stability constant of Cu(II) complexes may be due to the fact of more stable nature of Cu(II). The value of stability constant of Cu(II)—Ligand 2 complex is greater than that of Cu(II)-Ligand 1 and Cu(II)-Ligand 3. The same of Ni(II)-Ligand 3 complex is greater than that of Ni(II)-Ligand 1 and Ni(II)-Ligand 2.

  4. Formation of layered Fe(II)-Al(III)-hydroxides during reaction of Fe(II) with aluminum oxide.

    PubMed

    Elzinga, Evert J

    2012-05-01

    The reactivity of aqueous Fe(II) with aluminum oxide in anoxic solutions was investigated with batch kinetic experiments combined with Fe K edge X-ray absorption spectroscopy measurements to characterize Fe(II) sorption products. Formation of Fe(II)-Al(III)-layered double hydroxides with an octahedral sheet structure similar to nikischerite (NaFe(II)(6) Al(3)(SO(4))(2)(OH)(18) (H(2)O)(12)) was observed within a few hours during sorption at pH 7.5 and aqueous Fe(II) concentrations of 1-3 mM. These Fe(II) phases are composed of brucite-like Fe(II)(OH)(2) sheets with partial substitution of Al(III) for Fe(II), charge balanced by anions coordinated along the basal planes. Their fast rate of formation suggests that these previously unrecognized Fe(II) phases, which are structurally and compositionally similar to green rust, may be an important sink of Fe(II) in suboxic and anoxic geochemical environments, and impact the fate of structurally compatible trace metals, such as Co(II), Ni(II), and Zn(II), as well as redox-reactive species including Cr(VI) and U(VI). Further studies are required to assess the thermodynamics, formation kinetics, and stability of these Fe(II) minerals under field conditions. © 2012 American Chemical Society

  5. Cationic dirhodium(II,II) complexes for the electrocatalytic reduction of CO 2 to HCOOH

    DOE PAGES

    Witt, Suzanne E.; White, Travis A.; Li, Zhanyong; ...

    2016-09-22

    Two formamidinate bridged dirhodium(II,II) complexes with chelating diimine ligands L, [Rh 2(μ-DTolF) 2(L) 2] 2+, were shown to electrocatalytically reduce CO 2 in the presence of H 2O. Analysis of the reaction mixture and headspace following bulk electrolysis revealed H 2 and HCOOH as the major products. Finally, the variation in relative product formation is discussed.

  6. On the Nature of Ultra-faint Dwarf Galaxy Candidates. II. The Case of Cetus II

    NASA Astrophysics Data System (ADS)

    Conn, Blair C.; Jerjen, Helmut; Kim, Dongwon; Schirmer, Mischa

    2018-04-01

    We obtained deep Gemini GMOS-S g, r photometry of the ultra-faint dwarf galaxy candidate Cetus II with the aim of providing stronger constraints on its size, luminosity, and stellar population. Cetus II is an important object in the size–luminosity plane, as it occupies the transition zone between dwarf galaxies and star clusters. All known objects smaller than Cetus II (r h ∼ 20 pc) are reported to be star clusters, while most larger objects are likely dwarf galaxies. We found a prominent excess of main-sequence stars in the color–magnitude diagram of Cetus II, best described by a single stellar population with an age of 11.2 Gyr, metallicity of [Fe/H] = ‑1.28 dex, an [α/Fe] = 0.0 dex at a heliocentric distance of 26.3 ± 1.2 kpc. As well as being spatially located within the Sagittarius dwarf tidal stream, these properties are well matched to the Sagittarius galaxy’s Population B stars. Interestingly, like our recent findings on the ultra-faint dwarf galaxy candidate Tucana V, the stellar field in the direction of Cetus II shows no evidence of a concentrated overdensity despite tracing the main sequence for over six magnitudes. These results strongly support the picture that Cetus II is not an ultra-faint stellar system in the Milky Way halo, but made up of stars from the Sagittarius tidal stream.

  7. Potential future applications for the tracking and data relay satellite II (TDRS II) system

    NASA Technical Reports Server (NTRS)

    Gibbons, Richard C.

    1995-01-01

    During the conceptual design phases of the tracking and data relay satellite (TDRS) II system provision was made for a future service growth (FSG) payload with an undefined mission. The intent of the FSG was to provide a resource for TDRS II applications which would be available to meet a change in requirements for the operational TDRS II system. This paper summarizes the effect of the consideration of potential FSG applications imposed on the tracking and data relay satellite (TDRS) II system. The following applications were considered as FSG candidates: An optical 650 Mbps space-to-space link (SSL) coupled to an optical or RF downlink, an RF or optical crosslink to extend the baseline TDRS II system coverage, -zone of exclusion (ZOE) closure, relay for lunar communications either RF or optically, and relay for Martian communications either RF or optically. This paper summarizes work done in the 1990 time frame on the above stated applications. Since then, NASA has sponsored several studies (during phase B of the TDRS II development cycle) of the ZOE closure application of the FSG. The purpose of this paper is to report on the efforts previously considered for the FSG. A previous paper was presented at the 1991 Congress related to the second application above. This paper extends this effort to the four stated applications.

  8. The CAIN II (Controlled Access by Individual Number, Phase II) access-control system:

    SciTech Connect

    Rumble, R.P.; Jong, D.Y.; Kluz, S.M.

    1988-06-01

    This paper describes the access-control system that is being built at the Lawrence Livermore National Laboratory. Called the Controlled Access by Individual Number, Phase II (CAIN II) project, it is part of the Safeguards and Security Enhancements/endash/Phase 1 (SSE-1) line item. Under normal circumstances, the CAIN II system operates without human intervention. The CAIN II system consists of three major subsystems: The CAIN II Main Computer (CMC) subsystem/emdash/four DEC model 8250 VAX computers, connected in a cluster; The Front End Processor (FEP) subsystem/emdash/MicroVAX II computers driving communications servers; and The Entry-Control Device (ECD) subsystem/emdash/the actual equipment that controls personnel access.more » There are four types of entry-control devices: booths, single-door portals, staffed badge-readers, and sally ports. Several hundred entry-control devices may be connected to the access-control system. Each entry-control device contains the entire list of persons permitted to enter its controlled area and can make the GO/NO-GO decision about passage on its own.« less

  9. Synthesis, antimicrobial activity, structural and spectral characterization and DFT calculations of Co(II), Ni(II), Cu(II) and Pd(II) complexes of 4-amino-5-pyrimidinecarbonitrile

    NASA Astrophysics Data System (ADS)

    Mohamed, Tarek A.; Shaaban, Ibrahim A.; Farag, Rabei S.; Zoghaib, Wajdi M.; Afifi, Mahmoud S.

    2015-01-01

    Co(II), Ni(II), Cu(II) and Pd(II) complexes of 4-amino-5-pyrimidinecarbonitrile (APC) have been synthesized and characterized using elemental analysis, magnetic susceptibility, mass spectrometry, infrared (4000-200 cm-1), UV-Visible (200-1100 nm), 1H NMR and ESR spectroscopy as well as TGA analysis. The molar conductance measurements in DMSO imply non-electrolytic complexes, formulated as [M(APC)2Cl2] where M = Co(II), Ni(II), Cu(II) and Pd(II). The infrared spectra of Co(II), Ni(II) and Cu(II) complexes indicate a bidentate type of bonding for APC through the exocyclic amino and adjacent pyrimidine nitrogen as donors whereas APC coordinated to Pd(II) ion as a monodentated ligand via a pyrimidine nitrogen donor. The magnetic measurements and the electronic absorption spectra support distorted octahedral geometries for Co(II), Ni(II) and Cu(II) complexes however a square planar complex was favored for the Pd(II) complex (C2h skeleton symmetry). In addition, we carried out B3LYP and ω-B97XD geometry optimization at 6-31G(d) basis set except for Pd(II) where we implemented LanL2DZ/6-31G(d) combined basis set. The computational results favor all trans geometrical isomers where amino N, pyrimidine N and Cl are trans to each other (structure 1). Finally, APC and its divalent metal ion complexes were screened for their antibacterial activity, and the synthesized complexes were found to be more potent antimicrobial agents than APC against one or more microbial species.

  10. Generation of a Mouse Model for Arginase II Deficiency by Targeted Disruption of the Arginase II Gene

    PubMed Central

    Shi, Ou; Morris, Sidney M.; Zoghbi, Huda; Porter, Carl W.; O'Brien, William E.

    2001-01-01

    Mammals express two isoforms of arginase, designated types I and II. Arginase I is a component of the urea cycle, and inherited defects in arginase I have deleterious consequences in humans. In contrast, the physiologic role of arginase II has not been defined, and no deficiencies in arginase II have been identified in humans. Mice with a disruption in the arginase II gene were created to investigate the role of this enzyme. Homozygous arginase II-deficient mice were viable and apparently indistinguishable from wild-type mice, except for an elevated plasma arginine level which indicates that arginase II plays an important role in arginine homeostasis. PMID:11154268

  11. Regiones H II alrededor de estrellas WR

    NASA Astrophysics Data System (ADS)

    Giménez Benitez, S.; Niemela, V.

    En base a observaciones espectroscópicas en el rango óptico, obtenidas en el CASLEO, se estudian las condiciones físicas de tres regiones H II alrededor de estrellas WR: N76 en el entorno de Ab7, en la Nube Menor de Magallanes, N79 alrededor de Br 2, en la Nube Mayor de Magallanes y G2.4+1.4 alrededor de WR 102, en nuestra Galaxia. Estas regiones presentan una alta ionización. Se observa la línea nebular de HeII en 4686 Å . Utilizando líneas nebulares de diagnóstico, se derivan los valores de la densidad y la temperatura electrónica, así como también las abundancias de algunos de los elementos químicos nebulares.

  12. Delta II ICESAT Second Stage Arrival

    NASA Image and Video Library

    2017-12-18

    A convoy of vehicles accompanies the United Launch Alliance Delta II second stage on its way to the horizontal processing facility at Space Launch Complex-2 at Vandenberg Air Force Base in California. NASA's Ice, Cloud and land Elevation Satellite-2 (ICESat-2) will launch later this year on the final Delta II rocket. ICESat-2 will measure the height of a changing Earth, one laser pulse at a time, 10,000 laser pulses a second. The satellite will carry a single instrument, the Advanced Topographic Laser Altimeter System. ICESat-2 will help scientists investigate why, and how much our planet's frozen and icy areas, called the cryosphere, is changing in a warming climate.

  13. Delta II ICESAT Second Stage Arrival

    NASA Image and Video Library

    2017-12-18

    The United Launch Alliance Delta II second stage emerges from NASA's Building 1555 at Vandenberg Air Force Base in California. It will be transported to the horizontal processing facility at Space Launch Complex-2. NASA's Ice, Cloud and land Elevation Satellite-2 (ICESat-2) will launch later this year on the final Delta II rocket. ICESat-2 will measure the height of a changing Earth, one laser pulse at a time, 10,000 laser pulses a second. The satellite will carry a single instrument, the Advanced Topographic Laser Altimeter System. ICESat-2 will help scientists investigate why, and how much our planet's frozen and icy areas, called the cryosphere, is changing in a warming climate.

  14. Delta II ICESAT Second Stage Arrival

    NASA Image and Video Library

    2017-12-18

    The United Launch Alliance Delta II second stage arrives at NASA's Building 1555 at Vandenberg Air Force Base in California. It will be offloaded and prepared for transport to the horizontal processing facility at Space Launch Complex-2. NASA's Ice, Cloud and land Elevation Satellite-2 (ICESat-2) will launch later this year on the final Delta II rocket. ICESat-2 will measure the height of a changing Earth, one laser pulse at a time, 10,000 laser pulses a second. The satellite will carry a single instrument, the Advanced Topographic Laser Altimeter System. ICESat-2 will help scientists investigate why, and how much our planet's frozen and icy areas, called the cryosphere, is changing in a warming climate.

  15. Revisiting the photosystem II repair cycle

    PubMed Central

    Theis, Jasmine; Schroda, Michael

    2016-01-01

    ABSTRACT The ability of photosystem (PS) II to catalyze the light-driven oxidation of water comes along with its vulnerability to oxidative damage, in particular of the D1 core subunit. Photodamaged PSII undergoes repair in a multi-step process involving (i) reversible phosphorylation of PSII core subunits; (ii) monomerization and lateral migration of the PSII core from grana to stroma thylakoids; (iii) partial disassembly of PSII; (iv) proteolytic degradation of damaged D1; (v) replacement of damaged D1 protein with a new copy; (vi) reassembly of PSII monomers and migration back to grana thylakoids for dimerization and supercomplex assembly. Here we review the current knowledge on the PSII repair cycle. PMID:27494214

  16. 1996 Site environmental report. Volume II

    SciTech Connect

    NONE

    1997-09-01

    Ernest Orlando Lawrence Berkeley National Laboratory presents Volume II, data appendix as a reference document to supplement the 1996 Site Environmental Report. Volume II contains the raw environmental monitoring and sampling data used to generate many of the summary results included in the main report for both routine and nonroutine activities. This appendix includes a legend that cross-references the enclosed data tables with summary tables in the main report. The legend also provides a listing of more detailed descriptions for the station location codes used in the appendices` tables. Data presented in the tables are given in Systeme International (SI)more » units. The glossary found in the main report contains a listing of the SI units.« less

  17. TRUPACT-II 157 Examination Report

    SciTech Connect

    Barry H. O'Brien; Jeffrey M. Lacy; Kip E. Archibald

    2003-12-01

    This report presents the results of examination and recovery activities performed on the TRUPACT-II 157 shipping container. The container was part of a contact-handled transuranic waste shipment being transported on a truck to the Waste Isolation Pilot Plant in New Mexico when an accident occurred. Although the transport vehicle sustained only minor damage, airborne transuranic contamination was detected in air samples extracted from inside TRUPACT-II 157 at the Waste Isolation Pilot Plant. Consequently, the shipping container was rejected, resealed, and returned to the Idaho National Engineering and Environmental Laboratory where the payload was disassembled, examined, and recovered for subsequent reshipmentmore » to the Waste Isolation Pilot Plant. This report documents the results of those activities.« less

  18. The Bionic Clicker Mark I & II

    PubMed Central

    Magee, Elliott G.; Ourselin, S.; Nikitichev, Daniil; Vercauteren, T.; Vanhoestenberghe, Anne

    2017-01-01

    In this manuscript, we present two 'Bionic Clicker' systems, the first designed to demonstrate electromyography (EMG) based control systems for educational purposes and the second for research purposes. EMG based control systems pick up electrical signals generated by muscle activation and use these as inputs for controllers. EMG controllers are widely used in prosthetics to control limbs. The Mark I (MK I) clicker allows the wearer to change the slide of a presentation by raising their index finger. It is built around a microcontroller and a bio-signals shield. It generated a lot of interest from both the public and research community. The Mark II (MK II) device presented here was designed to be a cheaper, sleeker, and more customizable system that can be easily modified and directly transmit EMG data. It is built using a wireless capable microcontroller and a muscle sensor. PMID:28829413

  19. The Bionic Clicker Mark I & II.

    PubMed

    Magee, Elliott G; Ourselin, S; Nikitichev, Daniil; Vercauteren, T; Vanhoestenberghe, Anne

    2017-08-14

    In this manuscript, we present two 'Bionic Clicker' systems, the first designed to demonstrate electromyography (EMG) based control systems for educational purposes and the second for research purposes. EMG based control systems pick up electrical signals generated by muscle activation and use these as inputs for controllers. EMG controllers are widely used in prosthetics to control limbs. The Mark I (MK I) clicker allows the wearer to change the slide of a presentation by raising their index finger. It is built around a microcontroller and a bio-signals shield. It generated a lot of interest from both the public and research community. The Mark II (MK II) device presented here was designed to be a cheaper, sleeker, and more customizable system that can be easily modified and directly transmit EMG data. It is built using a wireless capable microcontroller and a muscle sensor.

  20. [Mania associated with Usher syndrome type II].

    PubMed

    Praharaj, Samir Kumar; Acharya, Mahima; Sarvanan, Arul; Kongasseri, Sreejayan; Behere, Rishikesh V; Sharma, P S V N

    2012-01-01

    Usher syndrome (or Hallgren syndrome) is an autosomal recessive genetic disorder characterized by sensorineural deafness, retinitis pigmentosa, and variable vestibular deficit; Usher syndrome type II is the most common form. Various neuropsychiatric disorders have been reported to occur in those with Usher syndrome, including schizophrenia-like disorder, atypical psychosis, recurrent depressive illness, neurotic disorder, and mental retardation; however, bipolar disorder is not common in those with Usher syndrome. Herein we describe a 30-year-old male with Usher syndrome type II that developed features indicative of a probable manic episode. The patient had complete remission of symptoms in response to treatment with olanzapine 20 mg d-1. In persons with dual sensory impairment there are inherent problems with assessment and diagnosis is difficult due to their limited communication abilities. The diagnosis of Usher syndrome depends heavily on behavioral observation and disturbances in vegetative functions.

  1. Delta II ICESat-2 Fairing Transport

    NASA Image and Video Library

    2018-02-23

    Both halves of the United Launch Alliance (ULA) Delta II rocket payload fairing were moved inside ULA's Building B8337 at Vandenberg Air Force Base in California. Technicians begin the process to remove them from their transporters. NASA's Ice, Cloud and land Elevation Satellite-2 (ICESat-2) will launch later this year on the final Delta II rocket. ICESat-2 will measure the height of a changing Earth, one laser pulse at a time, 10,000 laser pulses a second. The satellite will carry a single instrument, the Advanced Topographic Laser Altimeter System. ICESat-2 will help scientists investigate why, and how much our planet's frozen and icy areas, called the cryosphere, is changing in a warming climate.

  2. LSPRAY-II: A Lagrangian Spray Module

    NASA Technical Reports Server (NTRS)

    Raju, M. S.

    2004-01-01

    LSPRAY-II is a Lagrangian spray solver developed for application with parallel computing and unstructured grids. It is designed to be massively parallel and could easily be coupled with any existing gas-phase flow and/or Monte Carlo Probability Density Function (PDF) solvers. The solver accommodates the use of an unstructured mesh with mixed elements of either triangular, quadrilateral, and/or tetrahedral type for the gas flow grid representation. It is mainly designed to predict the flow, thermal and transport properties of a rapidly vaporizing spray because of its importance in aerospace application. The manual provides the user with an understanding of various models involved in the spray formulation, its code structure and solution algorithm, and various other issues related to parallelization and its coupling with other solvers. With the development of LSPRAY-II, we have advanced the state-of-the-art in spray computations in several important ways.

  3. Iron(II)-Catalyzed Hydrophosphination of Isocyanates.

    PubMed

    Sharpe, Helen R; Geer, Ana M; Lewis, William; Blake, Alexander J; Kays, Deborah L

    2017-04-18

    The first transition metal catalyzed hydrophosphination of isocyanates is presented. The use of low-coordinate iron(II) precatalysts leads to an unprecedented catalytic double insertion of isocyanates into the P-H bond of diphenylphosphine to yield phosphinodicarboxamides [Ph 2 PC(=O)N(R)C(=O)N(H)R], a new family of derivatized organophosphorus compounds. This remarkable result can be attributed to the low-coordinate nature of the iron(II) centers whose inherent electron deficiency enables a Lewis-acid mechanism in which a combination of the steric pocket of the metal center and substrate size determines the reaction products and regioselectivity. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  4. Delta II Second stage lift and mate

    NASA Image and Video Library

    2007-01-19

    On Pad 17-B at Cape Canaveral Air Force Station, the Delta II second stage is being lifted alongside the mobile service tower. Once inside, it will be mated with the first stage already in place. The Delta II is the launch vehicle for the THEMIS spacecraft. THEMIS consists of five identical probes, the largest number of scientific satellites ever launched into orbit aboard a single rocket. This unique constellation of satellites will resolve the tantalizing mystery of what causes the spectacular sudden brightening of the aurora borealis and aurora australis - the fiery skies over the Earth's northern and southern polar regions. THEMIS is scheduled to launch Feb. 15 from Cape Canaveral Air Force Station.

  5. Delta II Second stage lift and mate

    NASA Image and Video Library

    2007-01-19

    On Pad 17-B at Cape Canaveral Air Force Station, the Delta II second stage arrives at level 9 of the tower. The second stage will be moved inside and mated with the first stage already in place. The Delta II is the launch vehicle for the THEMIS spacecraft THEMIS consists of five identical probes, the largest number of scientific satellites ever launched into orbit aboard a single rocket. This unique constellation of satellites will resolve the tantalizing mystery of what causes the spectacular sudden brightening of the aurora borealis and aurora australis - the fiery skies over the Earth's northern and southern polar regions. THEMIS is scheduled to launch Feb. 15 from Cape Canaveral Air Force Station.

  6. Delta II Second stage lift and mate

    NASA Image and Video Library

    2007-01-19

    On Pad 17-B at Cape Canaveral Air Force Station, workers attach an overhead crane to the Delta II second stage in order to raise it to vertical. It will be lifted into the mobile service tower and mated with the first stage already in place. The Delta II is the launch vehicle for the THEMIS spacecraft. THEMIS consists of five identical probes, the largest number of scientific satellites ever launched into orbit aboard a single rocket. This unique constellation of satellites will resolve the tantalizing mystery of what causes the spectacular sudden brightening of the aurora borealis and aurora australis - the fiery skies over the Earth's northern and southern polar regions. THEMIS is scheduled to launch Feb. 15 from Cape Canaveral Air Force Station.

  7. Delta II Second stage lift and mate

    NASA Image and Video Library

    2007-01-19

    On Pad 17-B at Cape Canaveral Air Force Station, the Delta II second stage is lifted toward the mobile service tower. Once inside, it will be mated with the first stage already in place. The Delta II is the launch vehicle for the THEMIS spacecraft. THEMIS consists of five identical probes, the largest number of scientific satellites ever launched into orbit aboard a single rocket. This unique constellation of satellites will resolve the tantalizing mystery of what causes the spectacular sudden brightening of the aurora borealis and aurora australis - the fiery skies over the Earth's northern and southern polar regions. THEMIS is scheduled to launch Feb. 15 from Cape Canaveral Air Force Station.

  8. Adiem II end terminal for concrete barrier : final report.

    DOT National Transportation Integrated Search

    2001-03-01

    On September 9, 1997, an ADIEM II (Advanced Dynamic Impact Extension Module) was installed on Interstate 5 near Salem, Oregon. The ADIEM II offered a redirecting, energy-absorbing crash cushion and end treatment for portable and permanent protection ...

  9. Genetics Home Reference: hereditary sensory and autonomic neuropathy type II

    MedlinePlus

    ... Home Health Conditions HSAN2 Hereditary sensory and autonomic neuropathy type II Printable PDF Open All Close All ... expand/collapse boxes. Description Hereditary sensory and autonomic neuropathy type II ( HSAN2 ) is a condition that primarily ...

  10. Synthesis, spectroscopic characterization and biological activities of N4O2 Schiff base ligand and its metal complexes of Co(II), Ni(II), Cu(II) and Zn(II)

    NASA Astrophysics Data System (ADS)

    Al-Resayes, Saud I.; Shakir, Mohammad; Abbasi, Ambreen; Amin, Kr. Mohammad Yusuf; Lateef, Abdul

    The Schiff base ligand, bis(indoline-2-one)triethylenetetramine (L) obtained from condensation of triethylenetetramine and isatin was used to synthesize the complexes of type, [ML]Cl2 [M = Co(II), Ni(II), Cu(II) and Zn(II)]. L was characterized on the basis of the results of elemental analysis, FT-IR, 1H and 13C NMR, mass spectroscopic studies. The stoichiometry, bonding and stereochemistries of complexes were ascertained on the basis of results of elemental analysis, magnetic susceptibility values, molar conductance and various spectroscopic studies. EPR, UV-vis and magnetic moments revealed an octahedral geometry for complexes. L and its Cu(II) and Zn(II) complexes were screened for their antibacterial activity. Analgesic activity of Cu(II) and Zn(II) complexes was also tested in rats by tail flick method. Both complexes were found to possess good antibacterial and moderate analgesic activity.

  11. Synthesis, spectroscopic characterization, molecular modeling and antimicrobial activities of Mn(II), Co(II), Ni(II), Cu(II) complexes containing the tetradentate aza Schiff base ligand

    NASA Astrophysics Data System (ADS)

    Chandra, Sulekh; Ruchi

    2013-02-01

    Mn(II), Co(II), Ni(II), and Cu(II) complexes with a tetradentate macrocyclic ligand [1.2.5.6tetraoxo-3,4,7,8tetraaza-(1,2,3,4,5,6,7,8)tetrabenzene(L)] were synthesized and characterized by elemental analysis, molar conductance measurements, mass, nmr, i.r., electronic and e.p.r. spectral studies. All the complexes are non electrolytes in nature and may be formulated as [M(L)X2] [where, M = Mn(II), Co(II), Ni(II), Cu(II) and X = Cl-, CH3COO-]. On the basis of i.r., electronic and e.p.r. spectral studies a distorted octahedral geometry has been assigned for all complexes. The antimicrobial activities and LD50 values of the ligand and its complexes, as growth inhibiting agents, have been screened in vitro against two different species of bacteria and plant pathogenic fungi.

  12. 46 CFR 50.30-15 - Class II pressure vessels.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Fabrication Inspection § 50.30-15 Class II pressure vessels. (a) Class II pressure vessels shall be subject to... the fit-up of the vessel at this stage of fabrication, and in addition, observe the welding and...

  13. 46 CFR 50.30-15 - Class II pressure vessels.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Fabrication Inspection § 50.30-15 Class II pressure vessels. (a) Class II pressure vessels shall be subject to... the fit-up of the vessel at this stage of fabrication, and in addition, observe the welding and...

  14. Synthesis, characterization and in vitro anticancer activity of 18-membered octaazamacrocyclic complexes of Co(II), Ni(II), Cd(II) and Sn(II)

    NASA Astrophysics Data System (ADS)

    Kareem, Abdul; Zafar, Hina; Sherwani, Asif; Mohammad, Owais; Khan, Tahir Ali

    2014-10-01

    An effective series of 18 membered octaazamacrocyclic complexes of the type [MLX2], where X = Cl or NO3 have been synthesized by template condensation reaction of oxalyl dihydrazide with dibenzoylmethane and metal salt in 2:2:1 molar ratio. The formation of macrocyclic framework, stereochemistry and their overall geometry have been characterized by various physico-chemical studies viz., elemental analysis, electron spray ionization-mass spectrometry (ESI-MS), I.R, UV-Vis, 1H NMR, 13C NMR spectroscopy, X-ray diffraction (XRD) and TGA/DTA studies. These studies suggest formation of octahedral macrocyclic complexes of Co(II), Ni(II), Cd(II) and Sn(II). The molar conductance values suggest nonelectrolytic nature for all the complexes. Thermogravimatric analysis shows that all the complexes are stable up to 600 °C. All these complexes have been tested against different human cancer cell lines i.e. human hepatocellular carcinoma (Hep3B), human cervical carcinoma (HeLa), human breast adenocarcinoma (MCF7) and normal cells (PBMC). The newly synthesized 18-membered octaazamacrocyclic complexes during in vitro anticancer evaluation, displayed moderate to good cytotoxicity on liver (Hep3B), cervical (HeLa) and breast (MCF7) cancer cell lines, respectively. The most effective anticancer cadmium complex (C34H28N10CdO10) was found to be active with IC50 values, 2.44 ± 1.500, 3.55 ± 1.600 and 4.82 ± 1.400 in micro-molar on liver, cervical and breast cancer cell lines, respectively.

  15. The H II regions of IC 1613

    NASA Technical Reports Server (NTRS)

    Price, Jill S.; Mason, Stephen F.; Gullixson, Craig A.

    1990-01-01

    New H-alpha images are presented of IC 1613, a small irregular galaxy in the Local Group. The images, obtained with a CCD on the 42-in telescope at Lowell Observatory, have been calibrated and used to produce an H-alpha luminosity function and a size distribution for the H II regions in IC 1613. The results are compared to results for NGC 6822 and the Magellanic Clouds. The size distribution is found to be Poissonian over a limited range.

  16. Status of PLS-II Upgrade Program

    SciTech Connect

    Kim, Kyung-Ryul; Wiedemann, Helmut; Park, Sung-Ju

    2010-06-23

    The Pohang Light Source (PLS) at the Pohang Accelerator Laboratory has been operated first at 2.0 GeV since 1995, and later was upgraded to 2.5 GeV. During this time, 6 insertion devices like undulators and multipole wigglers have been put into operation to produce special photon beams, with a total of 27 beamlines installed and 3 beamlines under construction. Recently, Korea synchrotron user's community is demanding high beam stability, higher photon energies as well as more straight sections for insertion devices in the PLS. To meet the user requirements, the PLS-II upgrade program has been launched in January, 2009, incorporatingmore » a modified chromatic version of Double Bend Achromat (DBA) to achieve almost twice as many straight sections as the current PLS with a design goal of the relatively low emittance, {epsilon}, of 5.9 nm{center_dot}rad. In the PLS-II, the top-up injection using full energy linac is planned for much higher stable beam as well and thus the production of hard x-ray undulator radiation of 8 to 13 keV is anticipated to allow for the successful research program namely Protein Crystallography. The PLS-II machine components of storage ring, linear accelerator and photon beamlines will be partly dismantled and reinstalled in a 6-months shutdown beginning January, 2011 and then the PLS-II upgrade be started the initial commissioning with a 100 mA beam current from July in 2011.« less

  17. Plasma wakefield acceleration experiments at FACET II

    NASA Astrophysics Data System (ADS)

    Joshi, C.; Adli, E.; An, W.; Clayton, C. E.; Corde, S.; Gessner, S.; Hogan, M. J.; Litos, M.; Lu, W.; Marsh, K. A.; Mori, W. B.; Vafaei-Najafabadi, N.; O'shea, B.; Xu, Xinlu; White, G.; Yakimenko, V.

    2018-03-01

    During the past two decades of research, the ultra-relativistic beam-driven plasma wakefield accelerator (PWFA) concept has achieved many significant milestones. These include the demonstration of ultra-high gradient acceleration of electrons over meter-scale plasma accelerator structures, efficient acceleration of a narrow energy spread electron bunch at high-gradients, positron acceleration using wakes in uniform plasmas and in hollow plasma channels, and demonstrating that highly nonlinear wakes in the ‘blow-out regime’ have the electric field structure necessary for preserving the emittance of the accelerating bunch. A new 10 GeV electron beam facility, Facilities for Accelerator Science and Experimental Test (FACET) II, is currently under construction at SLAC National Accelerator Laboratory for the next generation of PWFA research and development. The FACET II beams will enable the simultaneous demonstration of substantial energy gain of a small emittance electron bunch while demonstrating an efficient transfer of energy from the drive to the trailing bunch. In this paper we first describe the capabilities of the FACET II facility. We then describe a series of PWFA experiments supported by numerical and particle-in-cell simulations designed to demonstrate plasma wake generation where the drive beam is nearly depleted of its energy, high efficiency acceleration of the trailing bunch while doubling its energy and ultimately, quantifying the emittance growth in a single stage of a PWFA that has optimally designed matching sections. We then briefly discuss other FACET II plasma-based experiments including in situ positron generation and acceleration, and several schemes that are promising for generating sub-micron emittance bunches that will ultimately be needed for both an early application of a PWFA and for a plasma-based future linear collider.

  18. Delta II JPSS-1 Interstage Lift & Mate

    NASA Image and Video Library

    2016-07-13

    The interstage of the United Launch Alliance Delta II rocket that will launch the Joint Polar Satellite System-1 (JPSS-1) is lifted at Space Launch Complex 2 on Vandenberg Air Force Base in California. JPSS, a next-generation environmental satellite system, is a collaborative program between the National Oceanic and Atmospheric Administration (NOAA) and NASA. To learn more about JPSS-1, visit www.jpss.noaa.gov.

  19. Collagen type II modification by hypochlorite.

    PubMed

    Olszowski, Sławomir; Mak, Paweł; Olszowska, Ewa; Marcinkiewicz, Janusz

    2003-01-01

    Oxidation of proteins is a common phenomenon in the inflammatory process mediated by highly reactive agents such as hypochlorite (HOCl/OCl(-)) produced by activated neutrophils. For instance, in rheumatoid arthritis hypochlorite plays an important role in joint destruction. One of the major targets for HOCl/OCl(-) is collagen type II (CII) - the primary cartilage protein. In our study, HOCl/OCl(-) mediated collagen II modifications were tested using various methods: circular dichroism (CD), HPLC, ELISA, dynamic light scattering (DLS), fluorimetry and spectrophotometry. It was shown that hypochlorite action causes deamination with consecutive carbonyl group formation and transformation of tyrosine residues to dichlorotyrosine. Moreover, it was shown that ammonium chloramine (NH(2)Cl) formed in the reaction mixture reacts with CII. However, in this case the yield of carbonyl groups and dichlorotyrosine is lower than that observed for HOCl/OCl(-) by 50%. CD data revealed that collagen II exists as a random coil in the samples and that chlorination is followed by CII fragmentation. In the range of low HOCl/OCl(-) concentrations (up to 1 mM) 10-90 kDa peptides are predominant whereas massive production of shorter peptides was observed for high (5 mM) hypochlorite concentration. DLS measurements showed that chlorination with HOCl/OCl(-) decreases the radius of collagen II aggregates from 30 to 6.8 nm. Taking into account the fact that chlorinated collagen is partially degraded, the DLS results suggest that smaller micelles are formed of the 10-90 kDa peptide fraction. Moreover, collagen chlorination results in epitope modification which affects CII recognition by anti-CII antibodies. Finally, since in the synovial fluid the plausible hypochlorite concentration is smaller than that used in the model the change of size of molecular aggregates seems to be the best marker of hypochlorite-mediated collagen oxidation.

  20. Delta II JPSS-1 Rocket on Pad

    NASA Image and Video Library

    2017-11-13

    At Vandenberg Air Force Base in California, this panoramic view shows the United Launch Alliance Delta II rocket at Space Launch Complex 2 from the gantry shortly after rollback. Preparations are underway to launch the Joint Polar Satellite System-1, or JPSS-1, spacecraft built by Ball Aerospace and Technologies Corp. of Boulder, Colorado. JPSS is the first in a series four next-generation environmental satellites in a collaborative program between the NOAA and NASA.

  1. Triangulum II. Not Especially Dense After All

    NASA Astrophysics Data System (ADS)

    Kirby, Evan N.; Cohen, Judith G.; Simon, Joshua D.; Guhathakurta, Puragra; Thygesen, Anders O.; Duggan, Gina E.

    2017-04-01

    Among the Milky Way satellites discovered in the past three years, Triangulum II has presented the most difficulty in revealing its dynamical status. Kirby et al. identified it as the most dark-matter-dominated galaxy known, with a mass-to-light ratio within the half-light radius of {3600}-2100+3500 {M}⊙ {L}⊙ -1. On the other hand, Martin et al. measured an outer velocity dispersion that is 3.5 ± 2.1 times larger than the central velocity dispersion, suggesting that the system might not be in equilibrium. From new multi-epoch Keck/DEIMOS measurements of 13 member stars in Triangulum II, we constrain the velocity dispersion to be {σ }v< 3.4 km s-1 (90% C.L.). Our previous measurement of {σ }v, based on six stars, was inflated by the presence of a binary star with variable radial velocity. We find no evidence that the velocity dispersion increases with radius. The stars display a wide range of metallicities, indicating that Triangulum II retained supernova ejecta and therefore possesses, or once possessed, a massive dark matter halo. However, the detection of a metallicity dispersion hinges on the membership of the two most metal-rich stars. The stellar mass is lower than galaxies of similar mean stellar metallicity, which might indicate that Triangulum II is either a star cluster or a tidally stripped dwarf galaxy. Detailed abundances of one star show heavily depressed neutron-capture abundances, similar to stars in most other ultra-faint dwarf galaxies but unlike stars in globular clusters. The data presented herein were obtained at the W. M. Keck Observatory, which is operated as a scientific partnership among the California Institute of Technology, the University of California and the National Aeronautics and Space Administration. The Observatory was made possible by the generous financial support of the W. M. Keck Foundation.

  2. Delta II JPSS-1 Spacecraft Arrival

    NASA Image and Video Library

    2017-09-01

    A technician at Vandenberg Air Force Base in California inspects the shipping container for the Joint Polar Satellite System-1, or JPSS-1, as it arrives at the Astrotech Processing Facility. JPSS is the first in a series four next-generation environmental satellites in a collaborative program between the National Oceanic and Atmospheric Administration (NOAA) and NASA. The satellite is scheduled to liftoff Nov. 10, 2017 atop a United Launch Alliance Delta II rocket.

  3. Delta II JPSS-1 Spacecraft Arrival

    NASA Image and Video Library

    2017-09-01

    Technicians at Vandenberg Air Force Base in California inspect the shipping container for the Joint Polar Satellite System-1, or JPSS-1, as it arrives at the Astrotech Processing Facility. JPSS is the first in a series four next-generation environmental satellites in a collaborative program between the National Oceanic and Atmospheric Administration (NOAA) and NASA. The satellite is scheduled to liftoff Nov. 10, 2017 atop a United Launch Alliance Delta II rocket.

  4. Level II Ergonomic Analyses, Dover AFB, DE

    DTIC Science & Technology

    1999-02-01

    IERA-RS-BR-TR-1999-0002 UNITED STATES AIR FORCE IERA Level II Ergonomie Analyses, Dover AFB, DE Andrew Marcotte Marilyn Joyce The Joyce...Antonio, Texas 78205 February 1999 Approved for public release; distribution is unlimited. DTIC QUALITY DISSECTED 1 Institute for Environment...Safety and Occupational Health Risk Analysis Risk Analysis Directorate Health and Safety Division 2513 Kennedy Circle Brooks Air Force Base TX 78235

  5. Plasma wakefield acceleration experiments at FACET II

    DOE PAGES

    Joshi, C.; Adli, E.; An, W.; ...

    2018-01-12

    During the past two decades of research, the ultra-relativistic beam-driven plasma wakefield accelerator (PWFA) concept has achieved many significant milestones. These include the demonstration of ultra-high gradient acceleration of electrons over meter-scale plasma accelerator structures, efficient acceleration of a narrow energy spread electron bunch at high-gradients, positron acceleration using wakes in uniform plasmas and in hollow plasma channels, and demonstrating that highly nonlinear wakes in the 'blow-out regime' have the electric field structure necessary for preserving the emittance of the accelerating bunch. A new 10 GeV electron beam facility, Facilities for Accelerator Science and Experimental Test (FACET) II, is currentlymore » under construction at SLAC National Accelerator Laboratory for the next generation of PWFA research and development. The FACET II beams will enable the simultaneous demonstration of substantial energy gain of a small emittance electron bunch while demonstrating an efficient transfer of energy from the drive to the trailing bunch. In this paper we first describe the capabilities of the FACET II facility. We then describe a series of PWFA experiments supported by numerical and particle-in-cell simulations designed to demonstrate plasma wake generation where the drive beam is nearly depleted of its energy, high efficiency acceleration of the trailing bunch while doubling its energy and ultimately, quantifying the emittance growth in a single stage of a PWFA that has optimally designed matching sections. Here, we briefly discuss other FACET II plasma-based experiments including in situ positron generation and acceleration, and several schemes that are promising for generating sub-micron emittance bunches that will ultimately be needed for both an early application of a PWFA and for a plasma-based future linear collider.« less

  6. Gerst during BASS-II experiment

    NASA Image and Video Library

    2014-07-30

    ISS040-E-083576 (30 July 2014) --- European Space Agency astronaut Alexander Gerst, Expedition 40 flight engineer, performs two tests with a combustion experiment known as the Burning and Suppression of Solids (BASS-II) in the Microgravity Science Glovebox (MSG) in the Destiny laboratory of the International Space Station. The experiment seeks to provide insight on how flames burn in space compared to Earth which may provide fire safety benefits aboard future spacecraft.

  7. Gerst during BASS-II experiment

    NASA Image and Video Library

    2014-07-30

    ISS040-E-083578 (30 July 2014) --- European Space Agency astronaut Alexander Gerst, Expedition 40 flight engineer, performs two tests with a combustion experiment known as the Burning and Suppression of Solids (BASS-II) in the Microgravity Science Glovebox (MSG) in the Destiny laboratory of the International Space Station. The experiment seeks to provide insight on how flames burn in space compared to Earth which may provide fire safety benefits aboard future spacecraft.

  8. Sensitivity of Escherichia coli (MutT) and human (MTH1) 8-oxo-dGTPases to in vitro inhibition by the carcinogenic metals, nickel(II), copper(II), cobalt(II) and cadmium(II).

    PubMed

    Porter, D W; Yakushiji, H; Nakabeppu, Y; Sekiguchi, M; Fivash, M J; Kasprzak, K S

    1997-09-01

    The toxicity of Ni(II), Co(II) and Cu(II) in animals, and that of Cd(II) in cultured cells, has been associated with generation of the promutagenic lesion 8-oxo-7,8-dihydroguanine (8-oxoguanine) in DNA, among other effects. One possible source of this base may be 8-oxo-7,8-dihydro-2'-deoxyguanosine-5'-triphosphate (8-oxo-dGTP), a product of oxidative damage to the nucleotide pool, from which it is incorporated into DNA. To promote such incorporation, the metals would have to inhibit specific cellular 8-oxo-dGTPases that eliminate 8-oxo-dGTP from the nucleotide pool. The present study was designed to test such inhibition in vitro on 8-oxo-dGTPases from two different species, the human MTH1 protein and Escherichia coli MutT protein. In the presence of Mg(II), the natural activator of 8-oxo-dGTPases, all four metals were found to inhibit both enzymes. For MTH1, the IC50 values (+/- SE; n = 3-4) were 17 +/- 2 microM for Cu(II), 30 +/- 8 microM for Cd(II), 376 +/- 71 microM for Co(II) and 801 +/- 97 microM for Ni(II). For MutT, they were 60 +/- 6 microM for Cd(II), 102 +/- 8 microM for Cu(II), 1461 +/- 96 microM for Ni(II) and 8788 +/- 1003 microM for Co(II). Thus, Cu(II) and Cd(II) emerged as much stronger inhibitors than Ni(II) and Co(II), and MTH1 appeared to be generally more sensitive to metal inhibition than MutT. Interestingly, in the absence of Mg(II), the activity of the enzymes could be restored by Co(II) to 73% of that with Mg(II) alone for MutT, and 34% for MTH1, the other metals being much less or non-effective. The difference in sensitivity to metal inhibition between the two enzymes may reflect the differences in the amino acid ligands, especially the cysteine ligand, outside their evolutionarily conserved Mg(II)-binding active sites, which might indicate predominantly non-competitive or uncompetitive mechanism of the inhibition. The overall results suggest that inhibition of 8-oxo-dGTPases may be involved in the mechanisms of induction of the 8

  9. Synthesis and characterization of new complexes of nickel (II), palladium (II) and platinum(II) with derived sulfonamide ligand: Structure, DFT study, antibacterial and cytotoxicity activities

    NASA Astrophysics Data System (ADS)

    Bouchoucha, Afaf; Zaater, Sihem; Bouacida, Sofiane; Merazig, Hocine; Djabbar, Safia

    2018-06-01

    The synthesis, characterization and biological study of new nickel (II), palladium (II), and platinum (II) complexes with sulfamethoxazole ligand used in pharmaceutical field, were reported. [MLCl2].nH2O is the general formula obtained for Pd(II) and Pt(II) complexes. These complexes have been prepared and characterized by elemental analysis, FTIR, 1HNMR spectral, magnetic measurements, UV-Visible spectra, and conductivity. The DFT calculation was applied to optimize the geometric structure of the Pd(II) and Pt(II) complexes. A new single-crystal X-ray structure of the Ni(II) complex has been determined. It crystallized in monoclinic system with P 21/c space group and Z = 8. The invitro antibacterial activity of ligand and complexes against Escherichia coli, P. aeruginosa, Klebsiella pneumoniae, S. aureus, Bacillus subtilis species has been carried out and compared using agar-diffusion method. The Pd(II) and Pt(II) complexes showed a remarkable inhibition against bacteria tested. The invitro cytotoxicity assay of the complexes against three cell lines chronic myelogenous leukaemia (K562), human colon adenocarcinoma (HT-29) and breast cancer (MCF-7) was also reported.

  10. Pomelo II: finding differentially expressed genes

    PubMed Central

    Morrissey, Edward R.; Diaz-Uriarte, Ramón

    2009-01-01

    Pomelo II (http://pomelo2.bioinfo.cnio.es) is an open-source, web-based, freely available tool for the analysis of gene (and protein) expression and tissue array data. Pomelo II implements: permutation-based tests for class comparisons (t-test, ANOVA) and regression; survival analysis using Cox model; contingency table analysis with Fisher's exact test; linear models (of which t-test and ANOVA are especial cases) that allow additional covariates for complex experimental designs and use empirical Bayes moderated statistics. Permutation-based and Cox model analysis use parallel computing, which permits taking advantage of multicore CPUs and computing clusters. Access to, and further analysis of, additional biological information and annotations (PubMed references, Gene Ontology terms, KEGG and Reactome pathways) are available either for individual genes (from clickable links in tables and figures) or sets of genes. The source code is available, allowing for extending and reusing the software. A comprehensive test suite is also available, and covers both the user interface and the numerical results. The possibility of including additional covariates, parallelization of computation, open-source availability of the code and comprehensive testing suite make Pomelo II a unique tool. PMID:19435879

  11. Status of the LCLS-II undulators

    SciTech Connect

    Wallén, E., E-mail: ejwallen@lbl.gov; Arbelaez, D.; Brown, A.

    2016-07-27

    The new free electron laser facility Linear Coherent Light Source II (LCLS-II) under construction at SLAC National Accelerator Laboratory will use planar variable gap undulators of hybrid type for the production of free electron laser (FEL) radiation. The LCLS-II will include two FELs with two separate rows of undulators to generate soft and hard x-rays. The soft x-rays will be produced by undulators with 39 mm period length (SXR) and the hard x-rays will be produced by undulators with 26 mm period length (HXR). Both the SXR and the HXR undulators are 3.4 m long and they use a commonmore » support structure and frame. In total 21 SXR and 32 HXR undulators will be produced by Lawrence Berkeley National Laboratory in collaboration with SLAC National Accelerator Laboratory. A full-scale prototype with 32 mm period length, called HXU, has been assembled at Lawrence Berkeley National Laboratory (LBNL). The present status of the design, prototyping, and pre-series production of the SXR and HXR undulators are presented in this paper together with the first results from measurements on the full scale HXU prototype.« less

  12. SRC-II environmental requirements. Draft

    SciTech Connect

    Barrett, M.; Richardson, S.

    1981-04-01

    A major goal of the DOE program to develop synthetic fuel processes is to reduce undesirable environmental, health, safety, and socioeconomic (EHS and S) effects of the processes. To meet this goal for the SRC-II demonstration plant, a number of activities have been proposed. This report identifies those activities that have been presented in the more formal documents generated during the program. They represent the DOE commitments to minimize, measure, and evaluate EHS and S effects. It was necessary, in most cases, to abstract from the formal documents listing the statements that are pertinent to EHS and S concerns. Theremore » does not appear to be a central document containing a focused program in which these commitments are addressed in a logical sequence. There appears to be no single organization for EHS and S activities in the SRC-II program. The coordination of EHS and S efforts under a single authority chartered as part of the program is recommended. If environmental, health, safety, and socioeconomic activities under the SRC-II demonstration program are dispersed among several organizations, there is danger of overlap of efforts, imbalance of funding, and possible oversight of major concerns that should be addressed in this program. The final section of this report lists seven activities that appear needed within such a program but have not been addressed in the documents studied.« less

  13. LCLS-II CRYOMODULE TRANSPORT SYSTEM TESTING

    SciTech Connect

    Huque, Naeem; Daly, Edward F.; McGee, Michael W.

    2018-04-01

    The Cryomodules (CM) for the Linear Coherent Light Source II (LCLS-II) will be shipped to SLAC (Menlo Park, California) from JLab (Newport News, Virginia) and FNAL (Batavia, Illinois). A transportation system has been designed and built to safely transport the CMs over the road. It uses an array of helical isolator springs to attenuate shocks on the CM to below 1.5g in all directions. The system rides on trailers equipped with Air-Ride suspension, which attenuates vibration loads. The prototype LCLS-II CM (pCM) was driven 750 miles to test the transport system; shock loggers recorded the shock attenuation on the pCMmore » and vacuum gauges were used to detect any compromises in beamline vacuum. Alignment measurements were taken before and after the trip to check whether cavity positions had shifted beyond the ± 0.2mm spec. Passband frequencies and cavity gradients were measured at 2K at the Cryomodule Test Facility (CMTF) at JLab to identify any degradation of CM performance after transportation. The transport system was found to have safely carried the CM and is cleared to begin shipments from JLab and FNAL to SLAC.« less

  14. Internal kinematics of H II galaxies

    NASA Astrophysics Data System (ADS)

    Carvalho, M. S.; Plana, H.

    2014-10-01

    H II galaxies are dwarf galaxies characterized by high stellar formation rate with spectrum dominated by strong emission lines, superimposed on a weak stellar continuum. The study of internal kinematics of these objects may be realized using the observed emission lines. Based on these lines we obtained monochromatic intensity, velocity dispersion and radial velocity maps. We have studied the internal kinematics of two H II galaxies: UM 461 and CTS 1020, observed with the Gemini South telescope using the GMOS instrument equipped with an IFU. We aim to investigate the origin of the line-broadening observed on emission lines from the use of kinematics diagnostic diagrams: I vs σ, I vs V, eV vs σ. The analysis of these diagrams was based on the Cometary Stirring Model that allows us to identify, for example, the presence of expanding shells and stellar winds. We found that radial velocity and velocity dispersion maps, for each galaxy, show a different kinematical pattern, although both are H II galaxies. CTS 1020 shows a velocity gradient consistent with a rotating disc with a velocity amplitude of ˜ 40 km s^{-1}. On the other hand UM 461 does not exhibit a typical pattern of a rotating system, despite of the observed velocity gradient in both emission nuclei.

  15. Chromospheric Activity in Population II Giants

    NASA Technical Reports Server (NTRS)

    Harper, Graham M.

    2004-01-01

    One of the mysteries of Population II giants is that they still show chromospheric emission despite their great age. The global dynamo which was active during their main-sequence lifetimes is expected to become extremely weak through magnetic rotational braking. The nature of the observed emission is not understood; although acoustic shock waves might provide the heating, acoustic waves are not predicted to drive the observed mass loss - which in turn requires the dissipation of magneto-hydrodynamic waves. This program was designed to search for the faint stellar H Ly beta emission wings and the fluorescent Fe II and H2 emission from one of the brightest, metal poor, Population II stars. These FUSE diagnostics, when combined with existing UV and optical spectra, help determine the major radiative cooling channels for the chromosphere. This observation was to complement that previously planned for the mildly metal deficient giant alpha Boo (K2 III). However, alpha Boo has yet to be observed with FUSE.

  16. Psychiatry and race during World War II.

    PubMed

    Dwyer, Ellen

    2006-04-01

    Although the American literature on "war neuroses" expanded during World War II, psychiatrists remained more interested in dramatic instances of "combat fatigue" than in the problems of soldiers who broke down far from the field of battle. This bias in the medical literature shaped both diagnosis and treatment. It had an especially powerful effect on African American soldiers who, in the "Jim Crow" army of World War II, were assigned in disproportionate numbers to service units. When military neuropsychiatrists did write about troubled young African Americans, many revealed a racial conservatism that was surprising given the liberal environmentalist paradigm of the day. (Here, a particularly useful source is the two-volume history of Neuropsychiatry in World War II, produced by the Medical Department of the U.S. Army.) The major challenge to such views came from the National Medical Association (NMA). Despite its many criticisms of military medicine, the NMA argued that African American soldiers and veterans needed more, not fewer, psychiatric services. NMA members also joined their white counterparts in the campaign to diminish the stigma of mental illness, especially among the families of soldiers returning home. We need more investigation of the subsequent history of race and psychiatry, especially within the Veterans Administration.

  17. TORY II-C NUCLEAR INSTRUMENTATION SYSTEM

    SciTech Connect

    Leger-Barter, G.St.

    1963-01-01

    The design of the nuclear instrumentation system for the Pluto series of nuclear ramjet test reactors is an attempt to provide a very flexible nuclear sensing system that will be adequate for Tory II-C and following test reactors. The nuclear detectors will be exposed to the leakage neutron flux from the reactor during operation. Since leakage flux is proportional to reactor power, the neutron detectors will give a measure of reactor power. A difficulty in providing nuclear instruments for this reactor is the uncertainty in the neutron energy spectrum of the leakage flux at the detectors. Since detector response variesmore » with neutron energy, a large margin of flexibility is desirable. A difficulty that may be encountered is a significant shift in neutron energy spectrum at high power and temperature. This shift would make indicated nuclear power nonlinear with calorimetric power. A difficulty in insufficient instrument overlap is encountered with the Tory II-A experiment, where a large margin of flexibility could be useful. The detector placement for the Tory II-A experiment has the power range detectors in line with the reactor and main air pipe. At high air flows there is a much greater mass of air between the detectors and the reactor, allowing fewer neutrons to reach the detectors per unit reactor power. This result is the reason for the power range detectors being placed off to the side of the Tory IIC test vehicle. (auth)« less

  18. Methods for preparation of cyclopentadienyliron (II) arenes

    DOEpatents

    Keipert, Steven J.

    1991-01-01

    Two improved methods for preparation of compounds with the structure shown in equation X [(Cp)--Fe--(Ar)].sup.+.sub.b X.sup.b- (X) where Cp is an eta.sup.5 complexed, substituted or unsubstituted, cyclopentadienyl or indenyl anion, Ar is an eta.sup.6 complexed substituted or unsubstituted, pi-arene ligand anad X is a b-valent anion where b is an integer between 1 and 3. The two methods, which differ in the source of the cyclopentadienyl anion - Lewis acid complex, utilize a Lewis acid assisted ligand transfer reaction. The cyclopentadienyl anion ligand, assisted by a Lewis acid is transferred to ferrous ion in the presence of an arene. In the first method, the cyclopentadienyl anion is derived from ferrocene and ferrous chloride. In this reaction, the cyclopentadienyliron (II) arene product is derived partially from ferrocene and partially from the ferrous salt. In the second method, the cyclopentadienyl anion - Lewis acid complex is formed by direct reaction of the Lewis acid with an inorganic cyclopentadienide salt. The cyclopentadienyliron (II) arene product of this reaction is derived entirely from the ferrous salt. Cyclopentadienyliron (II) arene cations are of great interest due to their utility as photoactivatable catalysts for a variety of polymerization reactions.

  19. AUGO II: a comprehensive subauroral zone observatory

    NASA Astrophysics Data System (ADS)

    Schofield, I. S.; Connors, M. G.

    2010-12-01

    A new geophysical observatory dedicated to the study of the aurora borealis will be built 25 km southwest of the town of Athabasca, Alberta, Canada. It is anticipated to see first light in the winter of 2010/2011 and be fully operational in the fall of 2011. Based on the highly successful Athabasca University Geophysical Observatory (AUGO), opened in 2002 at the Athabasca University campus in Athabasca, Alberta, AUGO II will have expanded observational capacity featuring up to eight climate-controlled domed optical observation suites for instrumentation, on-site accommodation for up to six researchers, and most importantly, dark skies free of light pollution from urban development. AUGO II will share the same advantages as its predecessor, one being its location in central Alberta, allowing routine study of the subauroral zone, auroral oval studies during active times, and very rarely of the polar cap. Like the original AUGO, AUGO II will be in close proximity to major highways, be connected to a high bandwidth network, and be within two hour driving distance to the city of Edmonton and its international airport. Opportunities are open for guest researchers in space physics to conduct auroral studies at this new, state-of-the-art research facility through the installation of remotely controlled instruments and/or campaigns. An innovative program of instrument development will accompany the new observatory’s enhanced infrastructure with a focus on magnetics and H-beta meridian scanning photometry.

  20. Sex differences in the drinking response to angiotensin II (AngII): Effect of body weight.

    PubMed

    Santollo, Jessica; Torregrossa, Ann-Marie; Daniels, Derek

    2017-07-01

    Sex differences in fluid intake stimulated by angiotensin II (AngII) have been reported, but the direction of the differences is inconsistent. To resolve these discrepancies, we measured water intake by male and female rats given AngII. Males drank more than females, but when intake was normalized to body weight, the sex difference was reversed. Weight-matched males and females, however, had no difference in intake. Using a linear mixed model analysis, we found that intake was influenced by weight, sex, and AngII dose. We used linear regression to disentangle these effects further. Comparison of regression coefficients revealed sex and weight differences at high doses of AngII. Specifically, after 100ng AngII, weight was a predictor of intake in males, but not in females. Next, we tested for differences in AngII-induced intake in male and females allowed to drink both water and saline. Again, males drank more water than females, but females showed a stronger preference for saline. Drinking microstructure analysis suggested that these differences were mediated by postingestive signals and more bottle switches by the females. Finally, we probed for differences in the expression of components of the renin-angiotensin system in the brains of males and females and found sex differences in several genes in discrete brain regions. These results provide new information to help understand key sex differences in ingestive behaviors, and highlight the need for additional research to understand baseline sex differences, particularly in light of the new NIH initiative to balance sex in biomedical research. Copyright © 2017 Elsevier Inc. All rights reserved.

  1. 40 CFR Appendix II to Subpart E - Sampling Tables

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Sampling Tables II Appendix II to Subpart E Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) NOISE ABATEMENT PROGRAMS... II to Subpart E—Sampling Tables Table 1—Model Year Production Volume of 50-99 Vehicles Cumulative...

  2. 20 CFR 404.1313 - World War II service excluded.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 2 2012-04-01 2012-04-01 false World War II service excluded. 404.1313... DISABILITY INSURANCE (1950- ) Wage Credits for Veterans and Members of the Uniformed Services World War II Veterans § 404.1313 World War II service excluded. Your service was not in the active service of the United...

  3. 20 CFR 404.1312 - World War II service included.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 2 2014-04-01 2014-04-01 false World War II service included. 404.1312... DISABILITY INSURANCE (1950- ) Wage Credits for Veterans and Members of the Uniformed Services World War II Veterans § 404.1312 World War II service included. Your service was in the active service of the United...

  4. 20 CFR 404.1313 - World War II service excluded.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 2 2014-04-01 2014-04-01 false World War II service excluded. 404.1313... DISABILITY INSURANCE (1950- ) Wage Credits for Veterans and Members of the Uniformed Services World War II Veterans § 404.1313 World War II service excluded. Your service was not in the active service of the United...

  5. 20 CFR 404.1313 - World War II service excluded.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 20 Employees' Benefits 2 2013-04-01 2013-04-01 false World War II service excluded. 404.1313... DISABILITY INSURANCE (1950- ) Wage Credits for Veterans and Members of the Uniformed Services World War II Veterans § 404.1313 World War II service excluded. Your service was not in the active service of the United...

  6. 20 CFR 404.1312 - World War II service included.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 2 2012-04-01 2012-04-01 false World War II service included. 404.1312... DISABILITY INSURANCE (1950- ) Wage Credits for Veterans and Members of the Uniformed Services World War II Veterans § 404.1312 World War II service included. Your service was in the active service of the United...

  7. 20 CFR 404.1312 - World War II service included.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 20 Employees' Benefits 2 2013-04-01 2013-04-01 false World War II service included. 404.1312... DISABILITY INSURANCE (1950- ) Wage Credits for Veterans and Members of the Uniformed Services World War II Veterans § 404.1312 World War II service included. Your service was in the active service of the United...

  8. Synthesis, characterization, and antioxidant/cytotoxic activity of new chromone Schiff base nano-complexes of Zn(II), Cu(II), Ni(II) and Co(II)

    NASA Astrophysics Data System (ADS)

    Saif, M.; El-Shafiy, Hoda F.; Mashaly, Mahmoud M.; Eid, Mohamed F.; Nabeel, A. I.; Fouad, R.

    2016-08-01

    A chromone Schiff base complexes of Zn(II) (1), Cu(II) (2), Ni(II) (3) and Co(II) (4) were successfully prepared in nano domain with crystalline or amorphous structures. The spectroscopic data revealed that the Schiff base ligand behaves as a monoanionic tridentate ligand. The metal complexes exhibited octahedral geometry. Transmission electron microscope (TEM) analysis showed that Cu(II) complex have aggregated nanospheres morphology. The obtained nano-complexes were tested as antioxidant and antitumor agents. The H2L and its Cu(II) complex (2) were found to be more potent antioxidant (IC50(H2L) = 0.93 μM; IC50(Cu(II) complex) = 1.1 μM than standard ascorbic acid (IC50 = 2.1 μM) as evaluated by DPPH• method. The H2L and its complexes (1-4) were tested for their in vitro cytotoxicity against Ehrlich Ascites Carcinoma cell line (EAC). The Cu(II) nano-complex (2) effectively inhibited EAC growth with IC50 value of 47 μM in comparison with its parent compound and other prepared complexes. The high antioxidant activity and antitumor activity of Cu(II) nano-complex (2) were attributed to their chemical structure, Cu(II) reducing capacity, and nanosize property. The toxicity test on mice showed that Zn(II) (1) and Cu(II) (2) nano-complex have lower toxicity than the standard cis-platin.

  9. 40 CFR Appendix II to Part 261 - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 25 2010-07-01 2010-07-01 false II Appendix II to Part 261 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) IDENTIFICATION AND LISTING OF HAZARDOUS WASTE Appendix II to Part 261 ...

  10. Determination of Pb(II), Zn(II), Cd(II), and Co(II) ions by flame atomic absorption spectrometry in food and water samples after preconcentration by coprecipitation with Mo(VI)-diethyldithiocarbamate.

    PubMed

    Tufekci, Mehmet; Bulut, Volkan Numan; Elvan, Hamide; Ozdes, Duygu; Soylak, Mustafa; Duran, Celal

    2013-02-01

    A new, simple, and rapid separation and preconcentration procedure, for determination of Pb(II), Cd(II), Zn(II), and Co(II) ions in environmental real samples, has been developed. The method is based on the combination of coprecipitation of analyte ions by the aid of the Mo(VI)-diethyldithiocarbamate-(Mo(VI)-DDTC) precipitate and flame atomic absorption spectrometric determinations. The effects of experimental conditions like pH of the aqueous solution, amounts of DDTC and Mo(VI), standing time, centrifugation rate and time, sample volume, etc. and also the influences of some foreign ions were investigated in detail on the quantitative recoveries of the analyte ions. The preconcentration factors were found to be 150 for Pb(II), Zn(II) and Co(II), and 200 for Cd(II) ions. The detection limits were in the range of 0.1-2.2 μg L(-1) while the relative standard deviations were found to be lower than 5 % for the studied analyte ions. The accuracy of the method was checked by spiked/recovery tests and the analysis of certified reference material (CRM TMDW-500 Drinking Water). The procedure was successfully applied to seawater and stream water as liquid samples and baby food and dried eggplant as solid samples in order to determine the levels of Pb(II), Cd(II), Zn(II), and Co(II) ions.

  11. 20 CFR 404.1312 - World War II service included.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false World War II service included. 404.1312... DISABILITY INSURANCE (1950- ) Wage Credits for Veterans and Members of the Uniformed Services World War II Veterans § 404.1312 World War II service included. Your service was in the active service of the United...

  12. 20 CFR 404.1313 - World War II service excluded.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false World War II service excluded. 404.1313... DISABILITY INSURANCE (1950- ) Wage Credits for Veterans and Members of the Uniformed Services World War II Veterans § 404.1313 World War II service excluded. Your service was not in the active service of the United...

  13. 40 CFR Appendix II to Subpart E - Sampling Tables

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Sampling Tables II Appendix II to Subpart E Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) NOISE ABATEMENT PROGRAMS... II to Subpart E—Sampling Tables Table 1—Model Year Production Volume of 50-99 Vehicles Cumulative...

  14. 40 CFR Appendix II to Subpart E - Sampling Tables

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Sampling Tables II Appendix II to Subpart E Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) NOISE ABATEMENT PROGRAMS... II to Subpart E—Sampling Tables Table 1—Model Year Production Volume of 50-99 Vehicles Cumulative...

  15. 40 CFR Appendix II to Part 86 - Temperature Schedules

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 19 2011-07-01 2011-07-01 false Temperature Schedules II Appendix II... Appendix II to Part 86—Temperature Schedules (a) Ambient temperature cycle for the diurnal emission portion of the evaporative emission test (see § 86.133). Table I—Temperature Versus Time Sequence Use linear...

  16. 40 CFR Appendix II to Part 86 - Temperature Schedules

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 19 2010-07-01 2010-07-01 false Temperature Schedules II Appendix II... Appendix II to Part 86—Temperature Schedules (a) Ambient temperature cycle for the diurnal emission portion of the evaporative emission test (see § 86.133). Table I—Temperature Versus Time Sequence Use linear...

  17. 40 CFR Appendix II to Part 86 - Temperature Schedules

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 20 2013-07-01 2013-07-01 false Temperature Schedules II Appendix II... Appendix II to Part 86—Temperature Schedules (a) Ambient temperature cycle for the diurnal emission portion of the evaporative emission test (see § 86.133). Table I—Temperature Versus Time Sequence Use linear...

  18. 40 CFR Appendix II to Part 86 - Temperature Schedules

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 20 2012-07-01 2012-07-01 false Temperature Schedules II Appendix II... Appendix II to Part 86—Temperature Schedules (a) Ambient temperature cycle for the diurnal emission portion of the evaporative emission test (see § 86.133). Table I—Temperature Versus Time Sequence Use linear...

  19. 10 CFR Appendix II to Part 504 - Fuel Price Computation

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 504—Fuel Price Computation (a) Introduction. This appendix provides the equations and parameters... responsible for computing the annual fuel price and inflation indices by using Equation II-1 and Equation II-2, respectively. The petitioner may compute the fuel price index specified in Equation II-1 or use his own price...

  20. 20 CFR 404.1313 - World War II service excluded.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 2 2011-04-01 2011-04-01 false World War II service excluded. 404.1313... DISABILITY INSURANCE (1950- ) Wage Credits for Veterans and Members of the Uniformed Services World War II Veterans § 404.1313 World War II service excluded. Your service was not in the active service of the United...

  1. 20 CFR 404.1312 - World War II service included.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 2 2011-04-01 2011-04-01 false World War II service included. 404.1312... DISABILITY INSURANCE (1950- ) Wage Credits for Veterans and Members of the Uniformed Services World War II Veterans § 404.1312 World War II service included. Your service was in the active service of the United...

  2. Lead(II) complex formation with glutathione.

    PubMed

    Mah, Vicky; Jalilehvand, Farideh

    2012-06-04

    A structural investigation of complexes formed between the Pb(2+) ion and glutathione (GSH, denoted AH(3) in its triprotonated form), the most abundant nonprotein thiol in biological systems, was carried out for a series of aqueous solutions at pH 8.5 and C(Pb(2+)) = 10 mM and in the solid state. The Pb L(III)-edge extended X-ray absorption fine structure (EXAFS) oscillation for a solid compound with the empirical formula [Pb(AH(2))]ClO(4) was modeled with one Pb-S and two short Pb-O bond distances at 2.64 ± 0.04 and 2.28 ± 0.04 Å, respectively. In addition, Pb···Pb interactions at 4.15 ± 0.05 Å indicate dimeric species in a network where the thiolate group forms an asymmetrical bridge between two Pb(2+) ions. In aqueous solution at the mole ratio GSH/Pb(II) = 2.0 (C(Pb(2+)) = 10 mM, pH 8.5), lead(II) complexes with two thiolate ligands form, characterized by a ligand-to-metal charge-transfer band (LMCT) S(-) → Pb(2+) at 317 nm in the UV-vis spectrum and mean Pb-S and Pb-(N/O) bond distances of 2.65 ± 0.04 and 2.51 ± 0.04 Å, respectively, from a Pb L(III)-edge EXAFS spectrum. For solutions with higher mole ratios, GSH/Pb(II) ≥ 3.0, electrospray ionization mass spectroscopy spectra identified a triglutathionyllead(II) complex, for which Pb L(III)-edge EXAFS spectroscopy shows a mean Pb-S distance of 2.65 ± 0.04 Å in PbS(3) coordination, (207)Pb NMR spectroscopy displays a chemical shift of 2793 ppm, and in the UV-vis spectrum, an S(-) → Pb(2+) LMCT band appears at 335 nm. The complex persists at high excess of GSH and also at ∼25 K in frozen glycerol (33%)/water glasses for GSH/Pb(II) mole ratios from 4.0 to 10 (C(Pb(2+)) = 10 mM) measured by Pb L(III)-edge EXAFS spectroscopy.

  3. Competitive adsorption of Cu(II) and Cd(II) ions by chitosan crosslinked with epichlorohydrin-triphosphate.

    PubMed

    Laus, Rogério; de Fávere, Valfredo Tadeu

    2011-10-01

    In this study, chitosan (CTS) was crosslinked with both epichlorohydrin (ECH) and triphosphate (TPP), by covalent and ionic crosslinking reactions, respectively. The resulting adsorbent (CTS-ECH-TPP) was characterized by SEM, CHN, EDS, FT-IR and TGA analyses, and tested for metal adsorption. The adsorbent was used in batch experiments to evaluate the adsorption of Cu(II) and Cd(II) ions in single and binary metal solutions. In single metal solutions the maximum adsorption capacities for Cu(II) and Cd(II) ions, obtained by Langmuir model, were 130.72 and 83.75 mg g⁻¹, respectively. Adsorption isotherms for binary solutions showed that the presence of Cu(II) decreased Cd(II) adsorption due to a significant competition effect, that is, the adsorbent was selective towards Cu(II) rather than Cd(II). Crown Copyright © 2011. Published by Elsevier Ltd. All rights reserved.

  4. Cluster II quartet take the stage together

    NASA Astrophysics Data System (ADS)

    1999-11-01

    This is the only occasion on which all four of ESA's Cluster II spacecraft will be on display together in Europe. Four Spacecraft, One Mission The unique event takes place near the end of the lengthy assembly and test programme, during which each individual spacecraft is being assembled in sequence, one after the other. Two have already completed their assembly and systems testing and are about to be stored in special containers at IABG prior to shipment to the Baikonur launch site in Kazakhstan next spring. In the case of the other two, flight models 5 and 8, installation of the science payloads has finished, but their exhaustive series of environmental tests at IABG have yet to begin. Following delivery to the launch site next April, the satellites will be launched in pairs in June and July 2000. Two Soyuz rockets, each with a newly designed Fregat upper stage, are being provided by the Russian-French Starsem company. This will be the first time ESA satellites have been launched from the former Soviet Union. Cluster II is a replacement for the original Cluster mission, which was lost during the maiden launch of Ariane 5 in June 1996. ESA, given the mission's importance in its overall strategy in the area of the Sun-Earth connection, decided to rebuild this unique project. ESA member states supported that proposal. On 3 April 1997, the Agency's Science Programme Committee agreed. Cluster II was born. European Teamwork Scientific institutions and industrial enterprises in almost all the 14 ESA member states and the United States are taking part in the Cluster II project. Construction of the eight Cluster / Cluster II spacecraft has been a major undertaking for European industry. Built into each 1200 kg satellite are six propellant tanks, two pressure tanks, eight thrusters, 80 metres of pipework, about 5 km of wiring, 380 connectors and more than 14 000 electrical contacts. All the spacecraft were assembled in the giant clean room at the Friedrichshafen plant of

  5. Reaction of a model siderophore with Ni(II), Co(II) and Zn(II) in aqueous solution: kinetics and spectroscopy.

    PubMed

    Barreto, Wagner J; Ando, Romulo A; Santos, Paulo S; Silva, Waleria P

    2008-02-01

    A spectroscopic study was performed showing that the [Fe(III)(L(2-))(2)](1-) (L(2-)=dopacatecholate) complex reacts with Ni(II), Co(II) and Zn(II) in an aqueous solution containing S(2)O(3)(2-) resulting in the soluble [M(L(1-))(3)](1-) (L(1-)=dopasemiquinone; M=Ni(II), Co(II) or Zn(II) complex species. The Raman and IR spectra of the [CTA][M(L(1-))(3)] complexes, CTA=hexadecyltrimethylammonium cation, in the solid state were obtained. The kinetic constants for the metal substitution reactions were determined at four different temperatures, providing values for DeltaH(not equal), DeltaS(not equal) and DeltaG(not equal). The reactions were slow (k=10(-11) Ms(-1)) and endothermic. The system investigated can be considered as a simplified model to explain some aspects of siderophore chemistry.

  6. Structural and functional characteristics of plant proteinase inhibitor-II (PI-II) family.

    PubMed

    Rehman, Shazia; Aziz, Ejaz; Akhtar, Wasim; Ilyas, Muhammad; Mahmood, Tariq

    2017-05-01

    Plant proteinase inhibitor-II (PI-II) proteins are one of the promising defensive proteins that helped the plants to resist against different kinds of unfavorable conditions. Different roles for PI-II have been suggested such as regulation of endogenous proteases, modulation of plant growth and developmental processes and mediating stress responses. The basic knowledge on genetic and molecular diversity of these proteins has provided significant insight into their gene structure and evolutionary relationships in various members of this family. Phylogenetic comparisons of these family genes in different plants suggested that the high rate of retention of gene duplication and inhibitory domain multiplication may have resulted in the expansion and functional diversification of these proteins. Currently, a large number of transgenic plants expressing PI-II genes are being developed for enhancing the defensive capabilities against insects, bacteria and pathogenic fungi. Much emphasis is yet to be given to exploit this ever expanding repertoire of genes for improving abiotic stress resistance in transgenic crops. This review presents an overview about the current knowledge on PI-II family genes, their multifunctional role in plant defense and physiology with their potential applications in biotechnology.

  7. Outer atmospheres of cool stars. II - Mg II flux profiles and chromospheric radiative loss rates

    NASA Technical Reports Server (NTRS)

    Basri, G. S.; Linsky, J. L.

    1979-01-01

    International Ultraviolet Explorer high-resolution spectra of the Mg II lines at 2796, 2803 A in 15 stars of spectral type G2-M2 including a wide range of luminosities are presented. These spectra are calibrated in absolute flux units at earth and at the stellar surface, and the chromospheric radiative loss rates in the Mg II lines are compared with corresponding rates in the Ca II H, K, and 8542 lines. The ratio of Mg II surface flux to total surface flux is found to be independent of stellar luminosity and thus gravity; may decrease slowly with decreasing effective temperature, and increases with decreasing period among RS Canum Venaticorum binaries. The factor of 10 range in this ratio at each effective temperature may be due to differences in the fractional surface area covered by plages and may indicate that stars of all luminosity classes have chromospheric plages. In this small data sample no evidence is found that the Mg II line surface fluxes indicate whether a star possesses a transition region and hot corona.

  8. Distance dependence of intrahelix Ru(II)* to Os(II) polypyridyl excited-state energy transfer in oligoproline assemblies.

    PubMed

    Brennaman, M Kyle; Fleming, Cavan N; Slate, Cheryl A; Serron, Scafford A; Bettis, Stephanie E; Erickson, Bruce W; Papanikolas, John M; Meyer, Thomas J

    2013-05-30

    Energy transfer between the metal-to-ligand charge transfer (MLCT) excited states of [Pra [M(II)(bpy)2(4-Me-4'(-N(H)CO)bpy)](PF6)2 units ([Pra(M(II)bpy2(mbpy)](2+): M(II) = Ru(II) or Os(II), bpy = 2,2'-bipyridine, mbpy = 4'-methyl-2,2'-bipyridine-4-carboxamido, Pra = 4-M(II)-L-proline) linked covalently to oligoproline assemblies in room temperature acetonitrile occurs on the picosecond-nanosecond time scale and has been time-resolved by transient emission measurements. Three derivatized oligoprolines, [CH3-CO-Pro6-Pra[Os(II)(bpy)2(mbpy)](2+)-Pro2-Pra[Ru(II)(bpy)2(mbpy)](2+)-Pro2-Pra[Ru(II)(bpy)2(mbpy)](2+)-Pro6-Glu-NH2](6+) (ORR-2, Pro = L-proline and Glu = glutamic acid); [CH3-CO-Pro6-Pra[Os(II)(bpy)2(mbpy)](2+)-Pro3-Pra[Ru(II)(bpy)2(mbpy)](2+)-Pro3-Pra[Ru(II)(bpy)2(mbpy)](2+)-Pro6-Glu-NH2](6+) (ORR-3); and CH3-CO-Pro6-Pra[Os(II)(bpy)2(mbpy)](2+)-Pro5-Pra[Ru(II)(bpy)2(mbpy)](2+)-Pro5-Pra[Ru(II)(bpy)2(mbpy)](2+)Pro6-Glu2-NH2](6+) (ORR-5), were prepared by using solid-phase peptide synthesis. Given the helical nature of the resulting assemblies and the nature of the synthesis, composition, length, and loading pattern are precisely controlled in the assemblies. In acetonitrile, they adopt a proline I helical secondary structure, confirmed by circular dichroism, in which the appended chromophores are ordered in well-defined orientations and internuclear separation distances although helix formation for ORR-2 is incomplete. Quantitative comparison of oligoproline ground-state absorption and steady-state emission spectra to those for the constituents, [Boc-Pra[M(II)(bpy)2(mbpy)](2+)-OH](PF6)2 (Boc = N(α)-(1,1-dimethylethoxycarbonyl), shows that following Ru(II) light absorption, Ru(II)* undergoes facile energy transfer resulting in sensitization of Os(II). Sensitization efficiencies are 93% for ORR-2, 77% for ORR-3, and 73% for ORR-5. Picosecond-resolved emission measurements reveal complex, coupled dynamics that arise from excited-state decay and kinetically

  9. Properties of anthranilate synthetase component II from Pseudomonas putida

    SciTech Connect

    Goto, Y.; Zalkin, H.; Keim, P.S.

    1976-02-25

    The interaction of Pseudomonas putida anthranilate synthetase Component II (AS II) with glutamine, glutamine analogs, and iodoacetamide has been investigated in order to clarify the initial steps in the mechanism for glutamine utilization. AS II is alkylated and irreversibly inactivated by covalent attachment of approximately 1 eq of L-2-amino-4-oxo-5-chloropentanoic acid (chloroketone) or 1 eq. of iodoacetamide. Alkylation of AS II by chloroketone involves initial formation of an enzyme-inhibitor complex having a K/sub i/ of 28 ..mu..M. Alkylation of AS II by iodoacetamide occurs without initial formation of a reversible complex. In both cases glutamine protects against alkylation and exhibits competitivemore » kinetics. When anthranilate synthetase Component I (AS I) is associated with AS II, the second substrate, chorismate, enhances alkylation of AS II by chloroketone. Alkylation of AS II by iodoacetamide is unaffected by AS I and chorismate. These results suggest a role of a chorismate AS I complex to promote binding of glutamine to AS II or to facilitate conversion of an AS II glutamine complex to the covalent glutamyl-AS II intermediate. This conclusion is supported by the fact that glutaminase activity of AS II, which requires formation of the glutamyl-AS II intermediate, is stimulated by AS I and chorismate. The dissociation constant for binding of glutamine to AS II is approximately 2.3 mM. The dissociation constant for binding of glutamine to AS I-AS II is approximately 1.3 mM. These binding constants are similar to the kinetic constants for glutamine determined in the overall reaction and the glutaminase reaction, and for competition against inactivation by chloroketone.« less

  10. Water exchange dynamics of manganese(II), cobalt(II), and nickel(II) ions in aqueous solution.

    PubMed

    Loffler, Hannes H; Mohammed, Ahmed M; Inada, Yasuhiro; Funahashi, Shigenobu

    2006-12-01

    The first row transition metal ions Mn(2+), Co(2+), and Ni(2+) have been studied by classical umbrella sampling molecular dynamics simulations. The water exchange mechanisms, estimates of reaction rates, as well as structural changes during the activation process are discussed. Mn(2+) was found to react via an I(A) mechanism, whereas Co(2+) and Ni(2+) both proceed via I(D). Reaction rate constants are generally higher than those obtained by experiment but the simply constructed metal(II) ion-water potential reproduces the relative order quite well.

  11. Study of the kinetics of the transport of Cu(II), Cd(II) and Ni(II) ions through a liquid membrane.

    PubMed

    Granado-Castro, María D; Galindo-Riaño, María D; Domínguez-Lledó, F C; Díaz-López, C; García-Vargas, M

    2008-06-01

    The coupled transport of Cu(II), Cd(II) and Ni(II) ions through a bulk liquid membrane (BLM) containing pyridine-2-acetaldehyde benzoylhydrazone (2-APBH) as carrier dissolved in toluene has been studied. Once the optimal conditions of extraction of each metal were established, a comparative study of the transport kinetics for these metals was performed by means of a kinetic model involving two consecutive irreversible first-order reactions. The kinetic parameters (apparent rate constants of the metal extraction and re-extraction reactions (k(1), k(2)), the maximum reduced concentration of the metal in the liquid membrane (R(o)max), the time of the maximum value of R(o)(t(max)) and the maximum entry and exit fluxes of the metal through the liquid membrane (J(f)max and J(s)max) of the extraction and stripping reactions were evaluated and results showed good agreement between experimental data and theoretical predictions. Complete transport through the membrane took place according to the following order: Cd(II)>Cu(II)>Ni(II), with similar kinetic parameters obtained for Cu(II) and Cd(III). The transport behaviour of Ni(II) was different to that of Cu(II) and Cd(III), probably due to the different stoichiometry of the nickel complex compared to those of the other metal ions and the different chemical conditions required for its formation. The influence of the sample salinity on the transport kinetics was studied. k(1) values decreased slightly when the feed solution salinity was increased for Cu(II) and Ni(II), but not for Cd(II). Values of k(2) were practically unaffected. The proposed BLM was applied to the preconcentration and separation of metal ions (prior to their determination) in water samples with different saline matrices (CRM, river water and seawater), and good agreement with the certified values was obtained.

  12. Carbonic Anhydrase Inhibitors. Part 461 Inhibition of Carbonic Anhydrase Isozymes I, II and IV With Trifluoromethylsulfonamide Derivatives and Their Zinc(II) and Copper(II) Complexes

    PubMed Central

    Mincione, Giovanna; Scozzafava, Andrea

    1997-01-01

    Reaction of aromatic/heterocyclic sulfonamides containing a free amino group with triflic anhydride afforded compounds possessing trifluoromethanesulfonamido moieties in their molecule. The Zn(II) and Cu(II) complexes of these new sulfonamides were prepared and characterized by standard procedures (elemental analysis, spectroscopic, magnetic, thermogravimetric and conductimetric measurements). The new derivatives showed good inhibitory activity against three isozymes of carbonic anhydrase (CA), i.e., CA I, II and IV. PMID:18475762

  13. 20 CFR 404.1340 - Wage credits for World War II and post-World War II veterans.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 2 2014-04-01 2014-04-01 false Wage credits for World War II and post-World... Uniformed Services Amounts of Wage Credits and Limits on Their Use § 404.1340 Wage credits for World War II and post-World War II veterans. In determining your entitlement to, and the amount of, your monthly...

  14. 20 CFR 404.1340 - Wage credits for World War II and post-World War II veterans.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 20 Employees' Benefits 2 2013-04-01 2013-04-01 false Wage credits for World War II and post-World... Uniformed Services Amounts of Wage Credits and Limits on Their Use § 404.1340 Wage credits for World War II and post-World War II veterans. In determining your entitlement to, and the amount of, your monthly...

  15. 20 CFR 404.1340 - Wage credits for World War II and post-World War II veterans.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 2 2012-04-01 2012-04-01 false Wage credits for World War II and post-World... Uniformed Services Amounts of Wage Credits and Limits on Their Use § 404.1340 Wage credits for World War II and post-World War II veterans. In determining your entitlement to, and the amount of, your monthly...

  16. Diet History Questionnaire II (DHQ II) for U.S. and Canada | EGRP/DCCPS/NCI/NIH

    Cancer.gov

    The Diet History Questionnaire II (DHQ II) is a freely available food frequency questionnaire (FFQ) for use by researchers, clinicians, or educators to assess food and dietary supplement intakes. The Canadian version of DHQ II is still available, but there is a newer U.S. version, DHQ III.

  17. 20 CFR 404.1340 - Wage credits for World War II and post-World War II veterans.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Wage credits for World War II and post-World War II veterans. 404.1340 Section 404.1340 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL... Uniformed Services Amounts of Wage Credits and Limits on Their Use § 404.1340 Wage credits for World War II...

  18. 20 CFR 404.1340 - Wage credits for World War II and post-World War II veterans.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 2 2011-04-01 2011-04-01 false Wage credits for World War II and post-World War II veterans. 404.1340 Section 404.1340 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL... Uniformed Services Amounts of Wage Credits and Limits on Their Use § 404.1340 Wage credits for World War II...

  19. Single molecule studies of RNA polymerase II transcription in vitro.

    PubMed

    Horn, Abigail E; Goodrich, James A; Kugel, Jennifer F

    2014-01-01

    Eukaryotic mRNA transcription by RNA polymerase II (RNAP II) is the first step in gene expression and a key determinant of cellular regulation. Elucidating the mechanism by which RNAP II synthesizes RNA is therefore vital to determining how genes are controlled under diverse biological conditions. Significant advances in understanding RNAP II transcription have been achieved using classical biochemical and structural techniques; however, aspects of the transcription mechanism cannot be assessed using these approaches. The application of single-molecule techniques to study RNAP II transcription has provided new insight only obtainable by studying molecules in this complex system one at a time.

  20. Iminodiacetic acid functionalized cation exchange resin for adsorptive removal of Cr(VI), Cd(II), Ni(II) and Pb(II) from their aqueous solutions.

    PubMed

    Misra, R K; Jain, S K; Khatri, P K

    2011-01-30

    Iminodiacetic acid functionality has been introduced on styrene-divinyl benzene co-polymeric beads and characterized by FT-IR in order to develop weak acid based cation exchange resin. This resin was evaluated for the removal of different heavy metal ions namely Cd(II), Cr(VI), Ni(II) and Pb(II) from their aqueous solutions. The results showed greater affinity of resin towards Cr(VI) for which 99.7% removal achieved in optimal conditions following the order Ni(II)>Pb(II)>Cd(II) with 65%, 59% and 28% removal. Experiments were also directed towards kinetic studies of adsorption and found to follow first order reversible kinetic model with the overall rate constants 0.3250, 0.2393, 0.4290 and 0.2968 for Cr(VI), Ni(II), Pb(II) and Cd(II) removal respectively. Detailed studies of Cr(VI) removal has been carried out to see the effect of pH, resin dose and metal ion concentration on adsorption and concluded that complexation enhanced the chromium removal efficacy of resin drastically, which is strongly pH dependent. The findings were also supported by the comparison of FT-IR spectra of neat resin with the chromium-adsorbed resin. Copyright © 2010 Elsevier B.V. All rights reserved.

  1. Biosorption properties of Cd(II), Pb(II), and Cu(II) of extracellular polymeric substances (EPS) extracted from Aspergillus fumigatus and determined by polarographic method.

    PubMed

    Yin, Yurong; Hu, Yongyou; Xiong, Fen

    2013-08-01

    Extracellular polymeric substances (EPS) were extracted from Aspergillus fumigatus using cationic exchange resin technique. The EPS were mainly composed of polysaccharide and low quantities of protein and nucleic acid. Biosorption of Cd(II), Pb(II), and Cu(II) of EPS was investigated as a function of pH using differential pulse polarography and the Ruzic model. Results showed that the EPS biosorption capacity determined using either the direct titration curves i = f(C M) or the method proposed by Ruzic (Analytica Chimica Acta 140:99-113, 1982) were coincident. Cu(II) had the highest affinity with EPS followed by Pb(II) and Cd(II). The total number of binding sites for Cu(II) and Cd(II) increased with pH in the range of 4.0-7.0. Similar trend was observed for Pb(II) at pH 4.0-5.0, while precipitates were observed at pH 6.0 and 7.0. The conditional binding constants of these three metals displayed low levels of fluctuation with pH and ranged from 4.02 ± 0.02 to 5.54 ± 0.05.

  2. Preconcentration of Cu(II), Co(II), and Ni(II) using an Optimized Enrichment Procedure: Useful and Alternative Methodology for Flame Atomic Absorption Spectrometry.

    PubMed

    Tokay, Feyzullah; Bağdat, Sema

    2016-03-01

    In this paper, a new solid phase extraction procedure is described for Cu(II), Co(II), and Ni(II). Silica gel which was coated with N,N'-bis(4-methoxysalicylidene) ethylenediamine (MSE) is used as a sorbent. Three independent variables were optimized using central composite design (CCD) for sorption and elution of metal ions. The optimum values of sorption and elution variables allowed simultaneous preconcentration of the ions in same conditions as follows, for sorption, pH 6.9, flow rate 5.4 mL min(-1), sample volume 50.0 mL, and for elution, flow rate 2.6 mL min(-1), eluent concentration 1.0 mol L(-1), eluent volume 5.0 mL. The detection limits (LOD) were found to be 1.1 µg L(-1) for Cu(II), 7.4 µg L(-1) for Co(II), and 7.5 µg L(-1) for Ni(II) and preconcentration factor was 200 for each of the ions. The accuracy of the method was tested with Lake Ontario water and multi-element standard solution. The proposed method was also applied to various water samples. The proposed method can be alternatively suggested as accurate, precise, easy, and a cheap method for Cu(II), Co(II), and Ni(II) determination. © The Author(s) 2016.

  3. Characterization and biological studies on Co(II), Ni(II) and Cu(II) complexes of carbohydrazones ending by pyridyl ring

    NASA Astrophysics Data System (ADS)

    Abu El-Reash, G. M.; El-Gammal, O. A.; Ghazy, S. E.; Radwan, A. H.

    2013-03-01

    The chelating behavior of ligands based on carbohydrazone core modified with pyridine end towards Co(II), Ni(II) and Cu(II) ions have been examined. The ligands derived from the condensation of carbohydrazide with 2-acetylpyridine (H2APC) and 4-acetylpyridine (H2APEC). The 1H NMR, IR data and the binding energy calculations of H2APC revealed the presence of two stereoisomers syn and anti in the solid state and in the solution. The 1H NMR, IR data and the binding energy calculations confirmed the presence of H2APEC in one keto form only in the solid state and in the solution. The spectroscopic data confirmed that H2APC behaves as a monobasic pentadentate in Co(II) and Cu(II) complexes and as mononegative tetradentate in Ni(II) complex. On the other hand, H2APEC acts as a mononegative tridentate in Co(II) complex, neutral tridentate in Ni(II) complex and neutral bidentate in Cu(II) complex. The electronic spectra and the magnetic measurements of complexes as well as the ESR of the copper complexes suggested the octahedral geometry. The bond length and bond angles were evaluated by DFT method using material studio program. The thermal behavior and the kinetic parameters of degradation were determined using Coats-Redfern and Horowitz-Metzger methods. The antioxidant (DDPH and ABTS methods), anti-hemolytic and in vitro Ehrlich ascites of the compounds have been screened.

  4. Synthesis, characterization, DFT and biological studies of isatinpicolinohydrazone and its Zn(II), Cd(II) and Hg(II) complexes

    NASA Astrophysics Data System (ADS)

    El-Gammal, O. A.; Rakha, T. H.; Metwally, H. M.; Abu El-Reash, G. M.

    2014-06-01

    Isatinpicolinohydrazone (H2IPH) and its Zn(II), Cd(II) and Hg(II) complexes have been synthesized and investigated using physicochemical techniques viz. IR, 1H NMR, 13C NMR, UV-Vis spectrometric methods and magnetic moment measurements. The investigation revealed that H2IPH acts as binegative tetradentate in Zn(II), neutral tridentate in Cd(II) and as neutral bidentate towards Hg(II) complex. Octahedral geometry is proposed for all complexes. The bond length, bond angle, chemical reactivity, energy components (kcal/mol), binding energy (kcal/mol) and dipole moment (Debyes) for all the title compounds were evaluated by DFT and also MEP for the ligand is shown. Theoretical infrared intensities of H2IPH and also the theoretical electronic spectra of the ligand and its complexes were calculated. The thermal behavior and the kinetic parameters of degradation were determined using Coats-Redfern and Horowitz-Metzger methods. The in vitro antibacterial studies of the complexes proved them as growth inhibiting agents. The DDPH antioxidant of the compounds have been screened. Antitumor activity, carried out in vitro on human mammary gland (breast) MCF7, have shown that Hg(II) complex exhibited potent activity followed by Zn(II), Cd(II) complexes and the ligand.

  5. Mechanism of Cu(II), Cd(II) and Pb(II) ions sorption from aqueous solutions by macroporous poly(glycidyl methacrylate-co-ethylene glycol dimethacrylate)

    NASA Astrophysics Data System (ADS)

    Nastasović, Aleksandra B.; Ekmeščić, Bojana M.; Sandić, Zvjezdana P.; Ranđelović, Danijela V.; Mozetič, Miran; Vesel, Alenka; Onjia, Antonije E.

    2016-11-01

    The mechanism of Cu(II), Cd(II) and Pb(II) ions sorption from aqueous solutions by macroporous poly(glycidyl methacrylate-co-ethylene glycol dimethacrylate) (PGME) functionalized by reaction of the pendant epoxy groups with diethylene triamine (PGME-deta) was studied using X-ray photoelectron spectroscopy (XPS) and Fourier transform infrared spectroscopy (FTIR) analysis. Atomic force microscopy (AFM) and scanning energy-dispersive X-ray spectroscopy (SEM-EDX) were used for the determination of surface morphology of the copolymer particles. The sorption behavior of heavy metals Cu(II), Cd(II) and Pb(II) ions sorption was investigated in batch static experiments under non-competitive conditions at room temperature (298 K). The obtained results were fitted to pseudo-first order, pseudo-second order and intraparticle diffusion kinetic model. The kinetics studies showed that Cu(II), Cd(II) and Pb(II) sorption obeys the pseudo-second-order model under all investigated operating conditions with evident influence of pore diffusion.

  6. A Combined MG II/CA II Survey of Stellar Magnetic Activity in the Solar Neighborhood

    NASA Technical Reports Server (NTRS)

    Wicklund, B. M.; Donahue, R. A.; Dobson, A. K.; Baliunas, Sallie L.

    1997-01-01

    We use nearly contemporaneus low-resolution IUE observations of Mg II h + k emission and Mount Wilson Observatory Ca II H + K S indices for 33 pairs of observations of lower main sequence stars to formulate a relationship that will permit accurate predictions of S values as a function of (B - V) color and Mg II h + k flux. The resulting relationship is useful because it will extend the set of solar neighborhood stars for which a uniform estimate of chromospheric activity is available to include stars that are not observable from Mount Wilson as well as providing additional estimates of activity levels for stars that are on the Mount Wilson HK Project observing list.

  7. Synthesis, spectroscopic characterization, molecular modeling and potentiometric studies of Co(II), Ni(II), Cu(II) and Zn(II) complexes with 1,1-diaminobutane-Schiff base

    NASA Astrophysics Data System (ADS)

    Alaghaz, Abdel-Nasser M. A.

    2014-08-01

    Complexes of cobalt(II), nickel(II), copper(II) and zinc(II) of general composition [M(L)(H2O)2]·2H2O have been synthesized [L = N,N";-bis(2-hydroxybenzylidene)-1,1-diaminobutane]. The elemental analysis, molar conductance measurements, magnetic susceptibility measurements, mass, IR, UV, NMR, SEM, EDX, thermal and EPR spectral studies of the compounds led to the conclusion that the ligand acts as a tetradentate manner. The molar conductance of the complexes in fresh solution of DMSO lies in the range of 7.46-9.13 Ω-1 cm2 mol-1 indicating their non-electrolytic behavior. On the basis of analytical and spectroscopic techniques, octahedral geometry of the complexes was proposed. The Schiff base acts as tetradentate ligand, coordinated through deprotonated phenolic oxygen and azomethine nitrogen atoms. The ligand field parameters were calculated for Co(II), Ni(II) and Cu(II) complexes and their values were found in the range reported for a octahedral structure. The molecular parameters of the ligand and its Co(II), Ni(II), Cu(II) and Zn(II) complexes have been calculated. Protonation constants of Schiff base and stability constants of their binary metal complexes have been determined potentiometrically in 50% DMSO-water media at 25 °C and ionic strength 0.10 M sodium perchlorate.

  8. Structural visualization of the p53/RNA polymerase II assembly

    PubMed Central

    Singh, Sameer K.; Qiao, Zhen; Song, Lihua; Jani, Vijay; Rice, William; Eng, Edward; Coleman, Robert A.; Liu, Wei-Li

    2016-01-01

    The master tumor suppressor p53 activates transcription in response to various cellular stresses in part by facilitating recruitment of the transcription machinery to DNA. Recent studies have documented a direct yet poorly characterized interaction between p53 and RNA polymerase II (Pol II). Therefore, we dissected the human p53/Pol II interaction via single-particle cryo-electron microscopy, structural docking, and biochemical analyses. This study reveals that p53 binds Pol II via the Rpb1 and Rpb2 subunits, bridging the DNA-binding cleft of Pol II proximal to the upstream DNA entry site. In addition, the key DNA-binding surface of p53, frequently disrupted in various cancers, remains exposed within the assembly. Furthermore, the p53/Pol II cocomplex displays a closed conformation as defined by the position of the Pol II clamp domain. Notably, the interaction of p53 and Pol II leads to increased Pol II elongation activity. These findings indicate that p53 may structurally regulate DNA-binding functions of Pol II via the clamp domain, thereby providing insights into p53-regulated Pol II transcription. PMID:27920087

  9. Fe (III), Co(II), Ni(II), Cu(II) and Zn(II) complexes of schiff bases based-on glycine and phenylalanine: Synthesis, magnetic/thermal properties and antimicrobial activity

    NASA Astrophysics Data System (ADS)

    Sevgi, Fatih; Bagkesici, Ugur; Kursunlu, Ahmed Nuri; Guler, Ersin

    2018-02-01

    Zinc (II), copper (II), nickel (II), cobalt (II) and iron (III) complexes of Schiff bases (LG, LP) derived from 2-hydroxynaphthaldehyde with glycine and phenylalanine were reported and characterized by 1H NMR, 13C NMR, elemental analyses, melting point, FT-IR, magnetic susceptibility and thermal analyses (TGA). TGA data show that iron and cobalt include to the coordinated water and metal:ligand ratio is 1:2 while the complex stoichiometry for Ni (II), Cu (II) and Zn (II) complexes is 1:1. As expected, Ni (II) and Zn (II) complexes are diamagnetic; Cu (II), Co (II) and Fe (III) complexes are paramagnetic character due to a strong ligand of LG and LP. The LG, LP and their metal complexes were screened for their antimicrobial activities against five Gram-positive (Staphylococcus aureus, Methicillin resistant Staphylococcus aureus (MRSA), Bacillus cereus, Streptococcus mutans and Enterococcus faecalis) and three Gram-negative (Escherichia coli, Klebsiella pneumoniae and Pseudomonas aeruginosa) and one fungi (Candida albicans) by using broth microdilution techniques. The activity data show that ligands and their metal complexes exhibited moderate to good activity against Gram-positive bacteria and fungi.

  10. Photoreactions of ruthenium(II) and osmium(II) complexes with deoxyribonucleic acid (DNA).

    PubMed

    Moucheron, C; Kirsch-De Mesmaeker, A; Kelly, J M

    1997-09-01

    The design of Ru(II) and Os(II) complexes which are photoreactive with deoxyribonucleic acid (DNA) represents one of the main targets for the development of novel molecular tools for the study of DNA and, in the future, for the production of new, metal-based, anti-tumor drugs. In this review, we explain how it is possible to make a complex photoreactive with nucleobases and nucleic acids. According to the photophysical behaviour of the Ru(II) compounds, two types of photochemistry are expected: (1) photosubstitution of a ligand by a nucleobase and another monodentate ligand, which takes place from the triplet, metal-centred (3MC) state; this state is populated thermally from the lowest lying triplet metal to ligand charge transfer (3MLCT) state; (2) photoreaction from the 3MLCT state, corresponding to photoredox processes with DNA bases. The two photoreactivities are in competition. By modulating appropriately the redox properties of the 3MLCT state, an electron transfer process from the base to the excited complex takes place, and is directly correlated with DNA cleavage or the formation of an adduct of the complex to DNA. In this adduct, guanine is linked by N2 to the alpha-position of a non-chelating nitrogen of the polyazaaromatic ligand without destruction of the complex. Different strategies are explained which increase the affinity of the complexes for DNA and direct the complex photoreactivity to sites of special DNA topology or targeted sequences of bases. Moreover, the replacement of the Ru(II) ion by the Os(II) ion in the photoreactive complexes leads to an increased specificity of photoreaction. Indeed, only one type of photoreactivity (from the 3MLCT state) is present for the Os(II) complexes because the 3MC state is too high in energy to be populated at room temperature.

  11. Competitive Removal of Cu(II) and Cd(II) from Water Using a Biocomposite Hydrogel.

    PubMed

    Maity, Jayabrata; Ray, Samit Kumar

    2017-12-07

    With an objective to improve the adsorption properties of a synthetic hydrogel, potato starch (PS) was incorporated in the ter-copolymer (TP) of acrylic acid (AA), acrylamide (AM), and bicarboxylic itaconic acid (IA) during polymerization of the monomers. The resulting TP-PS composite hydrogels were characterized by Fourier-transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), thermogravimetric analysis (TGA), nuclear magnetic resonance (NMR), scanning electron microscopy with energy dispersive X-ray spectroscopy (SEM/EDX), and rheological properties. These hydrogels were used for removal of Cu(II) and Cd(II) as single and binary competitive mixtures from water. The effect of PS as well as various physicochemical parameters such as solution pH, adsorbent dosage, contact time of gel with metal ion in water, and concentration of metal ion in water was studied in batch experiments. The adsorption results indicated that the gels could be used as an efficient adsorbent for removal of Cu(II) and Cd(II) from water as single as well as binary mixtures. The TP-PS4 gel containing 4 wt % starch showed a removal % of 85.8 and 77.6 and adsorption capacity (mg/g gel) of 214.5 and 193.9 for Cu(II) and Cd(II), respectively, from water containing 50 mg/L of each of these metal ions in a solution pH of 5.5 and a dose of only 0.2 g/L gel.

  12. LipidII: Just Another Brick in the Wall?

    PubMed Central

    Scheffers, Dirk-Jan; Tol, Menno B.

    2015-01-01

    Nearly all bacteria contain a peptidoglycan cell wall. The peptidoglycan precursor molecule is LipidII, containing the basic peptidoglycan building block attached to a lipid. Although the suitability of LipidII as an antibacterial target has long been recognized, progress on elucidating the role(s) of LipidII in bacterial cell biology has been slow. The focus of this review is on exciting new developments, both with respect to antibacterials targeting LipidII as well as the emerging role of LipidII in organizing the membrane and cell wall synthesis. It appears that on both sides of the membrane, LipidII plays crucial roles in organizing cytoskeletal proteins and peptidoglycan synthesis machineries. Finally, the recent discovery of no less than three different categories of LipidII flippases will be discussed. PMID:26679002

  13. Characterization and expression of MHC class II alpha and II beta genes in mangrove red snapper (Lutjanus argentimaculatus).

    PubMed

    Wang, Tianyan; Tan, Shangjin; Cai, Zhonghua

    2015-12-01

    The major histocompatibility complex (MHC) class II plays a key role in adaptive immunity by presenting foreign peptides to CD4(+) T cells and by triggering the adaptive immune response. While the structure and function of MHC class II have been well characterized in mammalian, limited research has been done on fishes. In this study, we characterized the gene structure and expression of MHC class II α (Lunar-DAA) and II β (Lunar-DAB) of mangrove red snapper (Lutjanus argentimaculatus). Both genes shared, respectively, a high similarity and typical features with other vertebrate MHC class II α and II β. The phylogenetic analysis of the deduced peptides revealed that both Lunar-DAA and Lunar-DAB were located in the teleost subclass. Western blotting analyses indicated that both MHC class II α and II β were expressed ubiquitously in immune-related cells, tissues and organs, and that MHC class II α and II β chains existed mainly as heterodimers. While it was highly expressed in gills, thymus, head kidney (HK), spleen, head kidney macrophage and spleen leucocytes, MHC class II β chain was expressed with a low abundance in skin, intestine, stomach and heart. The highest expression of MHC class II β in thymus confirmed the conclusion that thymus is one of the primary lymphoid organs in fishes. The detection of MHC class II αβ dimers in HK macrophages and spleen leucocytes indicated that HK macrophages and spleen leucocytes play a critical role in the adaptive immunity in fishes. All these results provide valuable information for understanding the structure of MHC class II α and II β and their function in immune responses. Copyright © 2015 Elsevier Ltd. All rights reserved.

  14. THE MASSES OF POPULATION II WHITE DWARFS

    SciTech Connect

    Kalirai, Jason S.; Davis, D. Saul; Richer, Harvey B.

    2009-11-01

    Globular star clusters are among the first stellar populations to have formed in the Milky Way, and thus only a small sliver of their initial spectrum of stellar types are still burning hydrogen on the main sequence today. Almost all of the stars born with more mass than 0.8 M{sub sun} have evolved to form the white dwarf cooling sequence of these systems, and the distribution and properties of these remnants uniquely holds clues related to the nature of the now evolved progenitor stars. With ultra-deep Hubble Space Telescope imaging observations, rich white dwarf populations of four nearby Milky Waymore » globular clusters have recently been uncovered, and are found to extend impressive 5-8 mag in the faint-blue region of the Hertzsprung-Russell diagram. In this paper, we characterize the properties of these population II remnants by presenting the first direct mass measurements of individual white dwarfs near the tip of the cooling sequence in the nearest of the Milky Way globulars, M4. Based on Gemini/GMOS and Keck/LRIS multiobject spectroscopic observations, our results indicate that 0.8 M{sub sun} population II main-sequence stars evolving today form 0.53 +- 0.01 M{sub sun} white dwarfs. We discuss the implications of this result as it relates to our understanding of stellar structure and evolution of population II stars and for the age of the Galactic halo, as measured with white dwarf cooling theory.« less

  15. Spectral modeling of Type II SNe

    NASA Astrophysics Data System (ADS)

    Dessart, Luc

    2015-08-01

    The red supergiant phase represents the final stage of evolution in the life of moderate mass (8-25Msun) massive stars. Hidden from view, the core changes considerably its structure, progressing through the advanced stages of nuclear burning, and eventually becomes degenerate. Upon reaching the Chandrasekhar mass, this Fe or ONeMg core collapses, leading to the formation of a proto neutron star. A type II supernova results if the shock that forms at core bounce, eventually wins over the envelope accretion and reaches the progenitor surface.The electromagnetic display of such core-collapse SNe starts with this shock breakout, and persists for months as the ejecta releases the energy deposited initially by the shock or continuously through radioactive decay. Over a timescale of weeks to months, the originally optically-thick ejecta thins out and turns nebular. SN radiation contains a wealth of information about the explosion physics (energy, explosive nucleosynthesis), the progenitor properties (structure and composition). Polarised radiation also offers signatures that can help constrain the morphology of the ejecta.In this talk, I will review the current status of type II SN spectral modelling, and emphasise that a proper solution requires a time dependent treatment of the radiative transfer problem. I will discuss the wealth of information that can be gleaned from spectra as well as light curves, from both the early times (photospheric phase) and late times (nebular phase). I will discuss the diversity of Type SNe properties and how they are related to the diversity of red supergiant stars from which they originate.SN radiation offers an alternate means of constraining the properties of red-supergiant stars. To wrap up, I will illustrate how SNe II-P can also be used as probes, for example to constrain the metallicity of their environment.

  16. Status of TJ-II project

    SciTech Connect

    Alejaldre, C.; Blaumoser, M.; Almoguera, L.

    1995-04-01

    The flexible Heliac TJ-II is a medium six device (R=1.5m, [a]=0.2 m, B(0)=1.0 T) in an advanced stage of construction at Centro de Investigaciones Energeticas Medio Ambientales y Tecnologicas (CIEMAT), Madrid. The problems encountered during manufacturing so far have been solved satisfactorily. Nevertheless the narrow tolerances, which result from the compact machine design, create real challenges for all the component manufacturers. In this paper we present the present status of the project with a particular emphasis on the construction situation of the main components. 1 ref., 2 figs., 1 tab.

  17. Atmospheric variability experiment /AVE II/ pilot experiment

    NASA Technical Reports Server (NTRS)

    Turner, R. E.; Scroggins, J. R.

    1974-01-01

    The Atmospheric Variability Experiment (AVE II) was conducted in May 1974. Rawinsonde releases were made at 54 upper-air stations in two thirds of the eastern U.S. at 3-hr intervals for a 24-hr period. Radar data were obtained from 11 stations located near the center of the observational area, and as many data as possible were collected from the Nimbus 5, NOAA 2, ATS-3, and DMSP satellites. The present paper provides an overview of the experiment and describes how the user community can obtain copies of the data.

  18. 40K Fastrac II Bantam Test

    NASA Technical Reports Server (NTRS)

    1997-01-01

    A close-up view of Bantam duration testing of the 40K Fastrac II Engine for X-34 at Marshall Space Flight Center's (MSFC) test stand 116. The Bantam test refers to the super lightweight engines of the Fastrac program. The engines were designed as part of the low cost X-34 Reusable Launch Vehicle (RLV). The testing of these engines at MSFC allowed the engineers to determine the capabilities of these engines and the metal alloys that were used in their construction. The Fastrac and X-34 programs were cancelled in 2001.

  19. Luminosity measurement with the CLEO II detector

    NASA Astrophysics Data System (ADS)

    Crawford, G.; Daubenmier, C. M.; Fulton, R.; Fujino, D.; Gan, K. K.; Honscheid, K.; Kagan, H.; Kass, R.; Lee, J.; Malchow, R.; Skovpen, Y.; Sung, M.; White, C.; Butler, F.; Fu, X.; Kalbfleisch, G.; Ross, W. R.; Skubic, P.; Wood, M.; Fast, J.; McIlwain, R. L.; Miao, T.; Miller, D. H.; Modesitt, M.; Payne, D.; Shibata, E. I.; Shipsey, I. P. J.; Wang, P. N.; Battle, M.; Ernst, J.; Gibbons, L.; Kwon, Y.; Roberts, S.; Thorndike, E. H.; Wang, C. H.; Dominick, J.; Lambrecht, M.; Sanghera, S.; Shelkov, V.; Skwarnicki, T.; Stroynowski, R.; Volobouev, I.; Wei, G.; Zadorozhny, P.; Artuso, M.; Goldberg, M.; He, D.; Horwitz, N.; Kennett, R.; Mountain, R.; Moneti, G. C.; Muheim, F.; Mukhin, Y.; Playfer, S.; Rozen, Y.; Stone, S.; Thulasidas, M.; Vasseur, G.; Xing, X.; Zhu, G.; Bartelt, J.; Csorna, S. E.; Egyed, Z.; Jain, V.; Kinoshita, K.; Edwards, K. W.; Ogg, M.; Bellerive, A.; Britton, D. I.; Hyatt, E. R. F.; MacFarlane, D. B.; Patel, P. M.; Barish, B.; Chadha, M.; Chan, S.; Cowen, D. F.; Eigen, G.; Miller, J. S.; O'Grady, C.; Urheim, J.; Weinstein, A. J.; Acosta, D.; Athanas, M.; Masek, G.; Paar, H. P.; Sivertz, M.; Gronberg, J.; Kutschke, R.; Menary, S.; Morrison, R. J.; Nakanishi, S.; Nelson, H. N.; Nelson, T. K.; Qiao, C.; Richman, J. D.; Ryd, A.; Tajima, H.; Sperka, D.; Witherell, M. S.; Procario, M.; Balest, R.; Cho, K.; Daoudi, M.; Ford, W. T.; Johnson, D. R.; Lingel, K.; Lohner, M.; Rankin, P.; Smith, J. G.; Alexander, J. P.; Bebek, C.; Berkelman, K.; Bloom, K.; Browder, T. E.; Cassel, D. G.; Cho, H. A.; Coffman, D. M.; Drell, P. S.; Ehrlich, R.; Gaiderev, P.; Galik, R. S.; Garcia-Sciveres, M.; Geiser, B.; Gittelman, B.; Gray, S. W.; Hartill, D. L.; Heltsley, B. K.; Jones, C. D.; Jones, S. L.; Kandaswamy, J.; Katayama, N.; Kim, P. C.; Kreinick, D. L.; Ludwig, G. S.; Masui, J.; Mevissen, J.; Mistry, N. B.; Ng, C. R.; Nordberg, E.; Patterson, J. R.; Peterson, D.; Riley, D.; Salman, S.; Sapper, M.; Würthwein, F.; Avery, P.; Freyberger, A.; Rodriguez, J.; Stephens, R.; Yang, S.; Yelton, J.; Cinabro, D.; Henderson, S.; Liu, T.; Saulnier, M.; Wilson, R.; Yamamoto, H.; Bergfeld, T.; Eisenstein, B. I.; Gollin, G.; Ong, B.; Palmer, M.; Selen, M.; Thaler, J. J.; Sadoff, A. J.; Ammar, R.; Ball, S.; Baringer, P.; Bean, A.; Besson, D.; Coppage, D.; Copty, N.; Davis, R.; Hancock, N.; Kelly, M.; Kotov, S.; Kravchenko, I.; Kwak, N.; Lam, H.; Kubota, Y.; Lattery, M.; Momayezi, M.; Nelson, J. K.; Patton, S.; Perticone, D.; Poling, R.; Savinov, V.; Schrenk, S.; Wang, R.; Alam, M. S.; Kim, I. J.; Nemati, B.; O'Neill, J. J.; Severini, H.; Sun, C. R.; Zoeller, M. M.; CLEO Collaboration

    1994-07-01

    A measurement of absolute integrated luminosity is presented using the CLEO II detector operating at the CESR e +e - storage ring. Independent analyses of three different final states (e +e -, γγ, and μ+μ-) at √s ⋍ 10 GeV normalize to the expected theoretical cross sections and correct for detection efficiencies. The resulting luminosities are measured with systematic errors of ±1.8%, ±1.6%, and ±2.2%, respectively, and are consistent with one another. The combined luminosity has a systematic error of ±1.0%.

  20. Science Driven Instrumentation for LCLS-II

    SciTech Connect

    Arthur, John; Bergmann, Uwe; Brunger, Axel

    2014-03-24

    The world’s first x-ray free electron laser (XFEL), LCLS, has now been operating for more than three years and all six experimental stations are supporting user science and producing high impact scientific results. Other countries are rapidly catching up and a second XFEL, SACLA, is already operating in Japan with others coming on line in Germany, Korea and Switzerland within the next three to five years. In order to increase capability and capacity of LCLS, the Department of Energy has funded LCLS-II.

  1. Delta II - SIRTF Lift and Mate

    NASA Image and Video Library

    2003-07-28

    Workers help guide the second stage of the Delta II Heavy rocket onto the first stage, below. The rocket will launch the Space Infrared Telescope Facility (SIRTF), currently scheduled for mid-August. SIRTF consists of three cryogenically cooled science instruments and an 0.85-meter telescope, and is one of NASA's largest infrared telescopes to be launched. SIRTF will obtain images and spectra by detecting the infrared energy, or heat, radiated by objects in space. Most of this infrared radiation is blocked by the Earth's atmosphere and cannot be observed from the ground.

  2. Delta II - SIRTF Lift and Mate

    NASA Image and Video Library

    2003-07-28

    On Launch Complex 17-B, Cape Canaveral Air Force Station, the second stage of the Delta II Heavy rocket is ready to be lifted up the mobile service tower. The rocket will launch the Space Infrared Telescope Facility (SIRTF), currently scheduled for mid-August. SIRTF consists of three cryogenically cooled science instruments and an 0.85-meter telescope, and is one of NASA's largest infrared telescopes to be launched. SIRTF will obtain images and spectra by detecting the infrared energy, or heat, radiated by objects in space. Most of this infrared radiation is blocked by the Earth's atmosphere and cannot be observed from the ground.

  3. Delta II - SIRTF Lift and Mate

    NASA Image and Video Library

    2003-07-28

    The second stage of the Delta II Heavy rocket is ready for mating onto the first stage, below. The rocket will launch the Space Infrared Telescope Facility (SIRTF), currently scheduled for mid-August. SIRTF consists of three cryogenically cooled science instruments and an 0.85-meter telescope, and is one of NASA's largest infrared telescopes to be launched. SIRTF will obtain images and spectra by detecting the infrared energy, or heat, radiated by objects in space. Most of this infrared radiation is blocked by the Earth's atmosphere and cannot be observed from the ground.

  4. Delta II - SIRTF Lift and Mate

    NASA Image and Video Library

    2003-07-28

    Workers on Launch Complex 17-B, Cape Canaveral Air Force Station, prepare for mating the second stage of the Delta II Heavy rocket to the first stage below. The rocket will launch the Space Infrared Telescope Facility (SIRTF), currently scheduled for mid-August. SIRTF consists of three cryogenically cooled science instruments and an 0.85-meter telescope, and is one of NASA's largest infrared telescopes to be launched. SIRTF will obtain images and spectra by detecting the infrared energy, or heat, radiated by objects in space. Most of this infrared radiation is blocked by the Earth's atmosphere and cannot be observed from the ground.

  5. PBFA II, the Pulsed Power Characterization Phase

    DTIC Science & Technology

    1987-06-01

    S. S. Payne, R. J. Commisso , J. M . Grossmann, D. D. Hinshelwood, R. A. Meger, J. M . Neri, W. F. Oliphant, P. F. Ottinger, B. V. Weber, "Plasma...Plasma Opening Switches," Appl. Phys. Lett., 42, 943 (1983). [31] B. V. Weber, J. R. Boller, R. J. Commisso , J. M . Grossmann, D. D. Hinshelwood, R. A...PBFA II, THE PULSED POYER CHARACTERIZATION PHASE T. H. Martin, B. N. Turman, S. A. Goldstein, J. M . Wilson, D. L. Cook D. H. McDaniel, E. L

  6. Delta II JPSS-1 Prelaunch Press Conference

    NASA Image and Video Library

    2017-11-12

    At Vandenberg Air Force Base in California, Scott Messer, United Launch Alliance program manager for NASA missions, speaks to members of the media at a prelaunch news conference for the Joint Polar Satellite System-1, or JPSS-1. Built by Ball Aerospace and Technologies Corp. of Boulder, Colorado, JPSS is the first in a series four next-generation environmental satellites in a collaborative program between the NOAA and NASA. Liftoff atop a United Launch Alliance Delta II rocket is scheduled to take place from Vandenberg's Space Launch Complex 2 at 1:47 a.m. PST (4:47 a.m. EST), on Nov. 14, 2017.

  7. Delta II JPSS-1 Prelaunch Press Conference

    NASA Image and Video Library

    2017-11-12

    At Vandenberg Air Force Base in California, Steve Volz, director of NOAA’s Satellite and Information Service, speaks to members of the media at a prelaunch news conference for the Joint Polar Satellite System-1, or JPSS-1. Built by Ball Aerospace and Technologies Corp. of Boulder, Colorado, JPSS is the first in a series four next-generation environmental satellites in a collaborative program between the NOAA and NASA. Liftoff atop a United Launch Alliance Delta II rocket is scheduled to take place from Vandenberg's Space Launch Complex 2 at 1:47 a.m. PST (4:47 a.m. EST), on Nov. 14, 2017.

  8. Anomalous Cepheids and population II blue stragglers

    NASA Astrophysics Data System (ADS)

    Nemec, James M.

    Recent studies of anomalous Cepheids (ACs) and population II blue stragglers (BSs), including photometrically variable BSs (VBSs), are reviewed. The VBSs represent about 25 percent of the BSs, the majority of which are SX Phe short-period variables in the Cepheid instability strip. Mass estimates derived using various techniques suggest that both ACs and BSs are relatively massive (about 1.0-1.6 solar mass). The recent discovery that two BSs in the globular cluster NGC 5466 are contact binaries, and the earlier discovery that one of the BSs in Omega Cen is an eclipsing binary, provide direct evidence that at least some BSs are binary systems.

  9. Delta II JPSS-1 Prelaunch Press Conference

    NASA Image and Video Library

    2017-11-12

    At Vandenberg Air Force Base in California, Tori McLendon, speaks to members of the media at a prelaunch news conference for the Joint Polar Satellite System-1, or JPSS-1. Built by Ball Aerospace and Technologies Corp. of Boulder, Colorado, JPSS is the first in a series four next-generation environmental satellites in a collaborative program between the NOAA and NASA. Liftoff atop a United Launch Alliance Delta II rocket is scheduled to take place from Vandenberg's Space Launch Complex 2 at 1:47 a.m. PST (4:47 a.m. EST), on Nov. 14, 2017.

  10. Control rod studies (Tory II-C)

    SciTech Connect

    Hadley, J.W.

    1962-11-15

    This memorandum outlines the area of interest in connection with the SSBN launch application, on modification of the Tory II-C control rod system; and suggest a plan of development of information. Because of the very limited space for overall missile length, little room is available for control rod motion upstream from the core. Shortening the rod stroke, and the total length occupied by control rod mechanism., becomes very desirable. Changes in the actuator and linkage mechanism will clearly help, and should be investigated. However, this is concerned only with neutronic aspects.

  11. EBR-II and TREAT Digitization Project

    SciTech Connect

    Griffith, George W.; Rabiti, Cristian

    2015-09-01

    Digitizing the technical drawings for EBR-II and TREAT provides multiple benefits. Moving the scanned or hard copy drawings to modern 3-D CAD (Computer Aided Drawing) format saves data that could be lost over time. The 3-D drawings produce models that can interface with other drawings to make complex assemblies. The 3-D CAD format can also include detailed material properties and parametric coding that can tie critical dimensions together allowing easier modification. Creating the new files from the old drawings has found multiple inconsistencies that are being flagged or corrected improving understanding of the reactor(s).

  12. Investigation of intermediates and transition states in the catalytic mechanisms of active site substituted cobalt(II), nickel(II), zinc(II), and cadmium(II) horse liver alcohol dehydrogenase

    SciTech Connect

    Dunn, M.F.; Dietrich, H.; MacGibbon, A.K.H.

    1982-01-12

    Active site substituted Co(II)-, Ni(II)-, and Cd(II)-horse liver alcohol dehydrogenase derivatives are compared to the native Zn(II)-enzyme with respect to the kinetic properties associated with the formation and decay of the intermediate observed in the reaction of the binary E-(NADH) complex with the intense substrate chromophore trans-4-(N,N-dimethylamino) cinnamaldehyde (DACA), lambda/sub max/ 398 nm (H/sub 2/O). All the metal ion subsituted enzymes were found to form intermediates with red-shifted spectra upon reaction with DACA and NADH. The magnitudes of (1) the red shifts, (2) the specific rate constants (k/sub off/) for dissociation of DACA from the intermediate, and (3) the hydridemore » transfer rate constants (k /sub H/) were found to correlate with the expected order of the Lewis acid acidities (assuming tetrahedral coordination); i.e., Co(II) > Ni(II) greater than or equal to Zn(II) >> Cd(II). The k/sub H/ value for the Co(II)-E was found to be 1.4-fold greater than the value of 7.2 s/sup -1/ for Zn(II)-E, while the Cd(II)-E was40-fold lower. It is concluded that the close similarities in kinetic properties exhibited by Co(II)-, Ni(II)-, and Zn(II)-enzymes arise from the close similarities in coordination geometries and Lewis acid strengths which lead to highly similar transition states for the processes of intemediate formation and decay. (JMT)« less

  13. Methodology and clinical significance of heparin cofactor II. Probable heparin cofactor II deficiency in a patient with cerebrovascular thrombosis.

    PubMed

    Tran, T H; Zbinden, B; Lämmle, B; Duckert, F

    1985-10-01

    HC II was functionally determined by thrombin inhibition in the presence of heparin in AT III-free plasma prepared by immunoadsorption on anti-AT III-Sepharose 4B column. HC II antigen concentration was assayed using specific antibodies to HC II. Simultaneously, AT III was measured. Plasma levels of HC II and AT III were determined in 110 patients with thrombotic tendency and two patients with obstetric complications and DIC. Highly significant correlations between activity and antigen prove the suitability of the methods. Reduced levels of HC II to about 50% with normal AT III values were repeatedly found in one patient with thrombotic tendency. The course of AT III and HC II during the process of DIC suggests that HC II may function as a thrombin inhibitor reserve when AT III becomes subnormally low.

  14. Synthesis, Characterization, Antimicrobial and Antiproliferative Activity Evaluation of Cu(II), Co(II), Zn(II), Ni(II) and Pt(II) Complexes with Isoniazid-Derived Compound.

    PubMed

    Pahonțu, Elena; Ilieș, Diana-Carolina; Shova, Sergiu; Oprean, Camelia; Păunescu, Virgil; Olaru, Octavian Tudorel; Rădulescu, Flavian Ștefan; Gulea, Aurelian; Roșu, Tudor; Drăgănescu, Doina

    2017-04-19

    Hydrazone complexes of Cu(II), Co(II), Zn(II), Ni(II) and Pt(II) with N -isonicotinoyl- N '-(3-metoxy-2 hydroxybenzaldehyde)-hydrazone ( HL ) were synthesized and characterized by different physico-chemical techniques including elemental and thermal analysis, magnetic susceptibility measurements, molar electric conductivity, as well as IR (infrared), ¹H-NMR and 13 C-NMR (hydrogen and carbon nuclear magnetic resonance, UV-Vis (ultraviolet-visible), FAB (fast atom bombardment), EPR (electron paramagnetic resonance), and mass spectroscopies. The crystal structure of ligand was determined by single crystal X-ray diffraction studies. Spectral data showed that hydrazone behaves as an ONO tridentate ligand through the azomethine nitrogen, phenolate and keto oxygen atoms. For the copper(II) complexes, metal-ligand bonding parameters were evaluated from the EPR spectra. These parameters indicate the presence of in-plane π bonding. In addition, the f values of complexes 1 - 4 indicate small distortion from planarity. The effect of these complexes on proliferation of human breast cancer (MCF-7 and SKBR-3), human melanoma (A375), lung adenocarcinoma cells (NCI-H1573) and their antibacterial activity against Escherichia coli , Klebsiella pneumoniae , Staphylococcus aureus and Candida albicans strains were studied and compared with those of free ligand. The ligand and complexes 1 - 3 showed significant antimicrobial activity against the Gram-positive bacteria Staphylococcus aureus and Candida albicans in comparison to the control drugs. The complexes 2 - 4 could be potential antitumor agents, leading to a significant improvement of the cytotoxic activity when compared with HL .

  15. NSLS-II Preliminary Design Report

    SciTech Connect

    Dierker, S.

    2007-11-01

    Following the CD0 approval of the National Synchrotron Light Source II (NSLS-II) during August 2005, Brookhaven National Laboratory prepared a conceptual design for a worldclass user facility for scientific research using synchrotron radiation. DOE SC review of the preliminary baseline in December 2006 led to the subsequent CD1 approval (approval of alternative selection and cost range). This report is the documentation of the preliminary design work for the NSLS-II facility. The preliminary design of the Accelerator Systems (Part 1) was developed mostly based of the Conceptual Design Report, except for the Booster design, which was changed from in-storage-ring tunnel configurationmore » to in external- tunnel configuration. The design of beamlines (Part 2) is based on designs developed by engineering firms in accordance with the specification provided by the Project. The conventional facility design (Part 3) is the Title 1 preliminary design by the AE firm that met the NSLS-II requirements. Last and very important, Part 4 documents the ES&H design and considerations related to this preliminary design. The NSLS-II performance goals are motivated by the recognition that major advances in many important technology problems will require scientific breakthroughs in developing new materials with advanced properties. Achieving this will require the development of new tools that will enable the characterization of the atomic and electronic structure, chemical composition, and magnetic properties of materials, at nanoscale resolution. These tools must be nondestructive, to image and characterize buried structures and interfaces, and they must operate in a wide range of temperatures and harsh environments. The NSLS-II facility will provide ultra high brightness and flux and exceptional beam stability. It will also provide advanced insertion devices, optics, detectors, and robotics, and a suite of scientific instruments designed to maximize the scientific output of the

  16. Extravehicular - Astronaut Edward H. White II

    NASA Image and Video Library

    1965-06-03

    S65-30202 (3 June 1965) --- Astronaut Edward H. White II, pilot on the Gemini-Titan IV (GT-4) spaceflight, floats in the zero gravity of space outside the Gemini IV spacecraft. His face is covered by a shaded visor to protect him from the unfiltered rays of the sun. White became the first American astronaut to walk in space. He remained outside the spacecraft for 21 minutes during the third revolution of the Gemini IV mission. He wears a specially designed spacesuit for the EVA. He?s holding the Hand-Held Self-Maneuvering Unit (HHSMU), with which he controlled his movements while in space, and a camera is attached to the HHSMU. He was attached to the spacecraft by a 25-feet umbilical line and a 23-feet tether line, both wrapped together with gold tape to form one cord. He wears an emergency oxygen supply check pack. Astronaut James A. McDivitt is command pilot for the GT-4 mission. The mission was a four-day, 62-revolution flight, during which McDivitt and White performed a series of scientific and engineering experiments. (This image is black and white) Photo credit: NASA EDITOR?S NOTE: Astronaut Edward H. White II died in the Apollo/Saturn 204 fire at Cape Kennedy, Florida, on Jan. 27, 1967.

  17. Fusion Power Demonstrations I and II

    SciTech Connect

    Doggett, J.N.

    1985-01-01

    In this report we present a summary of the first phase of the Fusion Power Demonstration (FPD) design study. During this first phase, we investigated two configurations, performed detailed studies of major components, and identified and examined critical issues. In addition to these design specific studies, we also assembled a mirror-systems computer code to help optimize future device designs. The two configurations that we have studied are based on the MARS magnet configuration and are labeled FPD-I and FPD-II. The FPD-I configuration employs the same magnet set used in the FY83 FPD study, whereas the FPD-II magnets are a new,more » much smaller set chosen to help reduce the capital cost of the system. As part of the FPD study, we also identified and explored issues critical to the construction of an Engineering Test Reactor (ETR). These issues involve subsystems or components, which because of their cost or state of technology can have a significant impact on our ability to meet FPD's mission requirements on the assumed schedule. General Dynamics and Grumman Aerospace studied two of these systems, the high-field choke coil and the halo pump/direct converter, in great detail and their findings are presented in this report.« less

  18. Spray Forming Aluminum - Final Report (Phase II)

    SciTech Connect

    D. D. Leon

    1999-07-08

    The U.S. Department of Energy - Office of Industrial Technology (DOE) has an objective to increase energy efficient and enhance competitiveness of American metals industries. To support this objective, ALCOA Inc. entered into a cooperative program to develop spray forming technology for aluminum. This Phase II of the DOE Spray Forming Program would translate bench scale spray forming technology into a cost effective world class process for commercialization. Developments under DOE Cooperative Agreement No. DE-FC07-94ID13238 occurred during two time periods due to budgetary constraints; April 1994 through September 1996 and October 1997 and December 1998. During these periods, ALCOA Incmore » developed a linear spray forming nozzle and specific support processes capable of scale-up for commercial production of aluminum sheet alloy products. Emphasis was given to alloys 3003 and 6111, both being commercially significant alloys used in the automotive industry. The report reviews research performed in the following areas: Nozzel Development, Fabrication, Deposition, Metal Characterization, Computer Simulation and Economics. With the formation of a Holding Company, all intellectual property developed in Phases I and II of the Project have been documented under separate cover for licensing to domestic producers.« less

  19. Software Quality Control at Belle II

    NASA Astrophysics Data System (ADS)

    Ritter, M.; Kuhr, T.; Hauth, T.; Gebard, T.; Kristof, M.; Pulvermacher, C.; Belle Software Group, II

    2017-10-01

    Over the last seven years the software stack of the next generation B factory experiment Belle II has grown to over one million lines of C++ and Python code, counting only the part included in offline software releases. There are several thousand commits to the central repository by about 100 individual developers per year. To keep a coherent software stack of high quality that it can be sustained and used efficiently for data acquisition, simulation, reconstruction, and analysis over the lifetime of the Belle II experiment is a challenge. A set of tools is employed to monitor the quality of the software and provide fast feedback to the developers. They are integrated in a machinery that is controlled by a buildbot master and automates the quality checks. The tools include different compilers, cppcheck, the clang static analyzer, valgrind memcheck, doxygen, a geometry overlap checker, a check for missing or extra library links, unit tests, steering file level tests, a sophisticated high-level validation suite, and an issue tracker. The technological development infrastructure is complemented by organizational means to coordinate the development.

  20. Conditions Database for the Belle II Experiment

    NASA Astrophysics Data System (ADS)

    Wood, L.; Elsethagen, T.; Schram, M.; Stephan, E.

    2017-10-01

    The Belle II experiment at KEK is preparing for first collisions in 2017. Processing the large amounts of data that will be produced will require conditions data to be readily available to systems worldwide in a fast and efficient manner that is straightforward for both the user and maintainer. The Belle II conditions database was designed with a straightforward goal: make it as easily maintainable as possible. To this end, HEP-specific software tools were avoided as much as possible and industry standard tools used instead. HTTP REST services were selected as the application interface, which provide a high-level interface to users through the use of standard libraries such as curl. The application interface itself is written in Java and runs in an embedded Payara-Micro Java EE application server. Scalability at the application interface is provided by use of Hazelcast, an open source In-Memory Data Grid (IMDG) providing distributed in-memory computing and supporting the creation and clustering of new application interface instances as demand increases. The IMDG provides fast and efficient access to conditions data via in-memory caching.

  1. NDCX-II target experiments and simulations

    DOE PAGES

    Barnard, J. J.; More, R. M.; Terry, M.; ...

    2013-06-13

    The ion accelerator NDCX-II is undergoing commissioning at Lawrence Berkeley National Laboratory (LBNL). Its principal mission is to explore ion-driven High Energy Density Physics (HEDP) relevant to Inertial Fusion Energy (IFE) especially in the Warm Dense Matter (WDM) regime. We have carried out hydrodynamic simulations of beam-heated targets for parameters expected for the initial configuration of NDCX-II. For metal foils of order one micron thick (thin targets), the beam is predicted to heat the target in a timescale comparable to the hydrodynamic expansion time for experiments that infer material properties from measurements of the resulting rarefaction wave. We have alsomore » carried out hydrodynamic simulations of beam heating of metallic foam targets several tens of microns thick (thick targets) in which the ion range is shorter than the areal density of the material. In this case shock waves will form and we derive simple scaling laws for the efficiency of conversion of ion energy into kinetic energy of fluid flow. Geometries with a tamping layer may also be used to study the merging of a tamper shock with the end-of-range shock. As a result, this process can occur in tamped, direct drive IFE targets.« less

  2. The MORPHEUS II protein crystallization screen

    SciTech Connect

    Gorrec, Fabrice, E-mail: fgorrec@mrc-lmb.cam.ac.uk

    2015-06-27

    MORPHEUS II is a 96-condition initial crystallization screen formulated de novo. The screen incorporates reagents selected from the Protein Data Bank to yield crystals that are not observed in traditional conditions. In addition, the formulation facilitates the optimization and cryoprotection of crystals. High-quality macromolecular crystals are a prerequisite for the process of protein structure determination by X-ray diffraction. Unfortunately, the relative yield of diffraction-quality crystals from crystallization experiments is often very low. In this context, innovative crystallization screen formulations are continuously being developed. In the past, MORPHEUS, a screen in which each condition integrates a mix of additives selected frommore » the Protein Data Bank, a cryoprotectant and a buffer system, was developed. Here, MORPHEUS II, a follow-up to the original 96-condition initial screen, is described. Reagents were selected to yield crystals when none might be observed in traditional initial screens. Besides, the screen includes heavy atoms for experimental phasing and small polyols to ensure the cryoprotection of crystals. The suitability of the resulting novel conditions is shown by the crystallization of a broad variety of protein samples and their efficiency is compared with commercially available conditions.« less

  3. Cobalt(II) selective membrane electrode based on palladium(II) dichloro acetylthiophene fenchone azine.

    PubMed

    Isa, I M; Mustafar, S; Ahmad, M; Hashim, N; Ghani, S A

    2011-12-15

    A new cobalt(II) ion selective electrode based on palladium(II) dichloro acetylthiophene fenchone azine(I) has been developed. The best membrane composition is found to be 10:60:10:21.1 (I)/PVC/NaTPB/DOP (w/w). The electrode exhibits a Nerstian response in the range of 1.0 × 10(-1)-1.0 × 10(-6)M with a detection limit and slope of 8.0 × 10(-7)M and 29.6 ± 0.2 mV per decade respectively. The response time is within the range of 20-25s and can be used for a period of up to 4 months. The electrode developed reveals good selectivity for cobalt(II) and could be used in pH range of 3-7. The electrode has been successfully used in the determination of cobalt(II) in water samples. Crown Copyright © 2011. Published by Elsevier B.V. All rights reserved.

  4. Program Activity/Training Plans. STIP II (Skill Training Improvement Programs Round II).

    ERIC Educational Resources Information Center

    Los Angeles Community Coll. District, CA.

    Detailed operational guidelines, training objectives, and learning activities are provided for the Los Angeles Community College District's Skill Training Improvement Programs (STIP II), which are designed to train students for immediate employment. The first of four reports covers Los Angeles Southwest College's computer programming trainee…

  5. Aviation Pilot Training II. Task Analyses: [Year II.] Field Review Copy.

    ERIC Educational Resources Information Center

    Upchurch, Richard

    This guide for aviation pilot II training begins with a course description, resource information, and a course outline. Tasks/competencies are categorized into 10 concept/duty areas: understanding aircraft staffs and procedures for safe recovery; understanding procedures for constant altitude turns; understanding procedures for traffic pattern…

  6. Lateral cephalometric diagnosis of asymmetry in Angle Class II subdivision compared to Class I and II.

    PubMed

    Meloti, Aparecida Fernanda; Gonçalves, Renata de Cássia; Silva, Ertty; Martins, Lídia Parsekian; dos Santos-Pinto, Ary

    2014-01-01

    Lateral cephalometric radiographs are traditionally required for orthodontic treatment, yet rarely used to assess asymmetries. The objective of the present study was to use lateral cephalometric radiographs to identify existing skeletal and dentoalveolar morphological alterations in Class II subdivision and to compare them with the existing morphology in Class I and II relationship. Ninety initial lateral cephalometric radiographs of male and female Brazilian children aged between 12 to 15 years old were randomly and proportionally divided into three groups: Group 1 (Class I), Group 2 (Class II) and Group 3 (Class II subdivision). Analysis of lateral cephalometric radiographs included angular measurements, horizontal linear measurements and two indexes of asymmetry that were prepared for this study. In accordance with an Index of Dental Asymmetry (IDA), greater mandibular dental asymmetry was identified in Group 3. An Index of Mandibular Asymmetry (IMA) revealed less skeletal and dental mandibular asymmetry in Group 2, greater skeletal mandibular asymmetry in Group 1, and greater mandibular dental asymmetry in Group 3. Both IDA and IMA revealed greater mandibular dental asymmetry for Group 3 in comparison to Groups 1 and 2. These results are in accordance with those found by other diagnostic methods, showing that lateral cephalometric radiography is an acceptable method to identify existing skeletal and dentoalveolar morphological alterations in malocclusions.

  7. Electrochemical Microsensors for the Detection of Cadmium(II) and Lead(II) Ions in Plants

    PubMed Central

    Krystofova, Olga; Trnkova, Libuse; Adam, Vojtech; Zehnalek, Josef; Hubalek, Jaromir; Babula, Petr; Kizek, Rene

    2010-01-01

    Routine determination of trace metals in complex media is still a difficult task for many analytical instruments. The aim of this work was to compare three electro-chemical instruments [a standard potentiostat (Autolab), a commercially available miniaturized potentiostat (PalmSens) and a homemade micropotentiostat] for easy-to-use and sensitive determination of cadmium(II) and lead(II) ions. The lowest detection limits (hundreds of pM) for both metals was achieved by using of the standard potentiostat, followed by the miniaturized potentiostat (tens of nM) and the homemade instrument (hundreds of nM). Nevertheless, all potentiostats were sensitive enough to evaluate contamination of the environment, because the environmental limits for both metals are higher than detection limits of the instruments. Further, we tested all used potentiostats and working electrodes on analysis of environmental samples (rainwater, flour and plant extract) with artificially added cadmium(II) and lead(II). Based on the similar results obtained for all potentiostats we choose a homemade instrument with a carbon tip working electrode for our subsequent environmental experiments, in which we analyzed maize and sunflower seedlings and rainwater obtained from various sites in the Czech Republic. PMID:22219663

  8. Oscillator Strengths for Ultraviolet Transitions in P II and Cu II for Interstellar Studies

    NASA Astrophysics Data System (ADS)

    Brown, Michael; Federman, S. R.; Curtis, L. J.; Cheng, S.; Irving, R. E.; Torok, S.; Schectman, R. M.

    2008-05-01

    Information on the makeup of the solid material in space as well as on the production of elements in our Galaxy and beyond may be gained through analysis of ultraviolet absorption from ions in interstellar clouds. High quality oscillator strengths are needed in order to convert the amount of absorption into an accurate abundance from data acquired with the Hubble Space Telescope and the Far Ultraviolet Spectroscopic Explorer. Lifetimes from our most recent beam-foil experiments for ultraviolet transitions in P II and Cu II are reported. When combined with our measured branching fractions, oscillator strengths for all transitions within the P II multiplet (3s23p2 3P-3s23p4s 3Po) at 1154 Å were determined. There was close agreement between our laboratory measurements and theoretical and semi-empirical calculations, suggesting a means for calibrating fast-beam instruments in the far ultraviolet. The Cu II results for the 1358 Å line (3d10 1S-3d9(2D)4p 3D0) provide further evidence for a short lifetime for the upper state of interest.

  9. Geochemistry of the alginite and amorphous organic matter from type II-S kerogens

    USGS Publications Warehouse

    Stankiewicz, B.A.; Kruge, M.A.; Mastalerz, Maria; Salmon, G.L.

    1996-01-01

    Maceral fractions of the Type II-S kerogens from the Monterey Formation (Miocene. California. U.S.A.) and Duwi Formation (Campanian/Maastrichtian, Egypt) were separated by density gradient centrifugation. The Monterey Fm. kerogen sample was comprised chiefly of light red-fluorescing amorphous organic matter (AOM), the flash pyrolyzate of which was characterized by a predominance of alkylbenzenes, alkylthiophenes and alkylpyrroles. In contrast, the pyrolyzates of its alginite concentrate showed a highly aliphatic character, typical of this maceral, with the series of n-alkenes and n-alkanes (C6- C26) predominating. The pyrolyzate of the dominant light brown-fluorescing AOM of the Duwi Fm. kerogen had a relatively high concentration of alkylbenzenes and alkylthiophenes, while its elginite concentrate showed a more aliphatic character upon pyrolysis. There was a marked enrichment of thiophenic sulfur in the light-colored AOM of both samples (and also pyrrolic nitrogen in the case of the Monterey) relative to the alginite. The results support a bacterially-mediated, degradative origin for Type II-S amorphous organic matter, with algal remains as the primary source of the kerogen.

  10. The Genocidal Mentality: Philip II of Spain and Sultan Abdul Hamid II.

    ERIC Educational Resources Information Center

    Kuttner, Robert E.

    1986-01-01

    Historical comparison of Sultan Abdul Hamid of Turkey and King Philip II of Spain with Adolph Hitler revealed similar personality traits, possibly characteristic determinants of individuals prone to undertake genocidal measures. Commitment to bureaucratic detail coupled with opportunistic belief in Messianic destiny are key factors in these…

  11. OUTLINE OF MATHEMATICS- LEVELS II A AND II B FOR TALENT PRESERVATION CLASSES IN GRADE EIGHT.

    ERIC Educational Resources Information Center

    Houston Public Schools, TX.

    MEASUREMENT, GEOMETRY, DECIMAL FRACTIONS, AND PERCENTAGE CONSTITUTE UNIT CONTENT FOR LEVEL II-A. NO STEP-BY-STEP PROCEDURES ARE GIVEN. EACH UNIT HAS GENERAL PROCEDURAL AND CONTENT APPROACH SUGGESTIONS. THE UNIT BEGINS WITH MEASUREMENT BECAUSE MOST CLASS MEMBERS WILL BE TAKING A PRACTICAL ARTS COURSE AND WILL NEED TO BE ABLE TO MEASURE MATERIALS.…

  12. Trident II (D-5) Sea-Launched Ballistic Missile UGM 133A (Trident II Missile)

    DTIC Science & Technology

    2013-12-01

    unfavorable net change in the schedule variance is due to stopping Interferometric Fiber Optic Gyro assembly operations as a result of a technical problem...with oxygen depletion in the fill gas causing a frequency response problem with an optoelectrical gyro part. Trident II Missile December 2013 SAR

  13. Angiotensin II signaling promotes follicle growth and dominance in cattle.

    PubMed

    Ferreira, Rogério; Gasperin, Bernardo; Rovani, Monique; Santos, Joabel; Barreta, Marcos; Bohrer, Rodrigo; Price, Christopher; Gonçalves, Paulo Bayard Dias

    2011-12-01

    It is generally understood that angiotensin II (AngII) promotes follicle atresia in rats, although recent data suggested that this may not be true in cattle. In this study, we aimed to determine in vivo whether AngII alters follicle development in cattle, using intrafollicular injection of AngII or antagonist into the growing dominant follicle or the second largest subordinate follicle. Injection of saralasin, an AngII antagonist, into the growing dominant follicle inhibited follicular growth, and this inhibitory effect was overcome by systemic FSH supplementation. Injection of AngII into the dominant follicle did not affect follicular growth, whereas injection of AngII into the second largest follicle prevented the expected atresia of this subordinate follicle, and the treated follicle grew at the same rate as the dominant follicle for the next 24 h. Inhibition of AngII action in the dominant follicle decreased estradiol concentrations in follicular fluid and the abundance of mRNA encoding aromatase, 3β-hydroxysteroid dehydrogenase, LH receptor, and cyclinD2 in granulosa cells, with minimal effects on theca cells. The effect of AngII on aromatase mRNA levels was confirmed using an in vitro granulosa cell culture system. In conclusion, these data suggest that AngII signaling promotes follicle growth in cattle and does so by regulating genes involved in estradiol secretion and granulosa cell proliferation and differentiation.

  14. Synthesis, magnetism and spectral studies of six defective dicubane tetranuclear {M4O6} (M = Ni(II), Co(II), Zn(II)) and three trinuclear Cd(II) complexes with polydentate Schiff base ligands.

    PubMed

    Jiang, Lin; Zhang, Dong-Yan; Suo, Jing-Jing; Gu, Wen; Tian, Jin-Lei; Liu, Xin; Yan, Shi-Ping

    2016-06-21

    A series of Ni(II), Co(II), Zn(II) and Cd(II) complexes with polytopic Schiff base ligands have been synthesized. The single-crystal X-ray crystallography results show that tetranuclear complexes have common face-shared defective dicubane cores, whereas trinuclear Cd(II) complexes are almost linear entities. Synthesis methods (solvent evaporation and hydrothermal synthesis), reaction conditions (pH, solvents and dosage) and coligands (azide, methanol, chloride and acetate) play vital roles in determining the final structure of the complexes and therefore their magnetic properties. In complexes , the terminal and central M(2+) ions are connected through mixed bridges, μ-phenoxido/μ1,1,1-X and μ-Oalphatic/μ1,1,1-X, while central two M(2+) ions are linked by double bridges, μ1,1,1-X (X = azido and methoxido groups for and respectively). For complex , two central Ni(II) ions are connected through two μ1,1,1-N3(-) which is relatively less reported. For complexes , there are two kinds of Cd(II), the centre Cd(II) ions are eight-coordinated with triangle dodecahedral geometries, while the two side Cd(II) ions are six-coordinated with trigonal prism geometries using chlorides or acetates as terminal ligands. Magnetic susceptibility measurements (χM) for compounds have been performed, and they reveal predominant ferromagnetic exchange interactions in Co(II) and Ni(II) tetramers. The photoluminescence studies show that the Zn(II) complex and three Cd(II) complexes have strong fluorescence, and the lifetimes are measured to be in the 10(2) nanosecond timescale.

  15. Synthesis, characterization and anti-microbial activity of a novel macrocyclic ligand derived from the reaction of 2,6-pyridinedicarboxylic acid with homopiperazine and its Co(II), Ni(II), Cu(II), and Zn(II) complexes

    NASA Astrophysics Data System (ADS)

    Soleimani, Esmaiel

    2011-05-01

    The preparation of a novel macrocyclic ligand ( 1), N,N'-diethylhomopiperazinyl,2,6-pyridinedicarboxylate and its Co(II), Ni(II), Cu(II), and Zn(II) complexes are described. The ligand was prepared in EtOH from the reaction of dipotassium salt of 2,6-pyridinedicarboxylic acid with 1,2-dibromoethane in the presence of homopiperazine. Reaction of macrocyclic ligand ( 1) in EtOH with CoCl 2.6H 2O, NiCl 2.6H 2O, CuCl 2.2H 2O, and ZnCl 2·2H 2O yielded the complexes with the general formula [M(L)Cl 2] {where M = Co(II) ( 2), Ni(II) ( 3), Cu(II) ( 4), Zn ( 5), respectively}. The analysis of IR, 1H and 13C NMR spectral data of macrocyclic ligand ( 1) and its Zn(II) complex ( 5) together with their molar conductivity values, and the magnetic moments of the complexes suggest that the macrocyclic ligand ( 1) is bonded to metal(II) ions through two oxygen atoms of ester moiety and the two nitrogen atoms of homopiperazine ring. The electronic spectral data of these complexes in DMSO are in good agreement with the octahedral coordination of M(II) ions. The ligand field parameters for these complexes, i.e. splitting energy and Racah parameter were calculated to be 14,945 and 673 cm -1 for the Co(II) ( 2), 16,260 and 774 cm -1 for the Ni(II) ( 3) complexes respectively. The spliting energy of 17,262 cm -1 was obtained for the Cu(II) complex ( 4).

  16. Unsupervised Clustering of Type II Supernova Light Curves

    NASA Astrophysics Data System (ADS)

    Rubin, Adam; Gal-Yam, Avishay

    2016-09-01

    As new facilities come online, the astronomical community will be provided with extremely large data sets of well-sampled light curves (LCs) of transients. This motivates systematic studies of the LCs of supernovae (SNe) of all types, including the early rising phase. We performed unsupervised k-means clustering on a sample of 59 R-band SN II LCs and find that the rise to peak plays an important role in classifying LCs. Our sample can be divided into three classes: slowly rising (II-S), fast rise/slow decline (II-FS), and fast rise/fast decline (II-FF). We also identify three outliers based on the algorithm. The II-FF and II-FS classes are disjoint in their decline rates, while the II-S class is intermediate and “bridges the gap.” This may explain recent conflicting results regarding II-P/II-L populations. The II-FS class is also significantly less luminous than the other two classes. Performing clustering on the first two principal component analysis components gives equivalent results to using the full LC morphologies. This indicates that Type II LCs could possibly be reduced to two parameters. We present several important caveats to the technique, and find that the division into these classes is not fully robust. Moreover, these classes have some overlap, and are defined in the R band only. It is currently unclear if they represent distinct physical classes, and more data is needed to study these issues. However, we show that the outliers are actually composed of slowly evolving SN IIb, demonstrating the potential of such methods. The slowly evolving SNe IIb may arise from single massive progenitors.

  17. (1)H NMR assignment corrections and (1)H, (13)C, (15)N NMR coordination shifts structural correlations in Fe(II), Ru(II) and Os(II) cationic complexes with 2,2'-bipyridine and 1,10-phenanthroline.

    PubMed

    Pazderski, Leszek; Pawlak, Tomasz; Sitkowski, Jerzy; Kozerski, Lech; Szłyk, Edward

    2010-06-01

    (1)H, (13)C and (15)N NMR studies of iron(II), ruthenium(II) and osmium(II) tris-chelated cationic complexes with 2,2'-bipyridine and 1,10-phenanthroline of the general formula [M(LL)(3)](2+) (M = Fe, Ru, Os; LL = bpy, phen) were performed. Inconsistent literature (1)H signal assignments were corrected. Significant shielding of nitrogen-adjacent protons [H(6) in bpy, H(2) in phen] and metal-bonded nitrogens was observed, being enhanced in the series Ru(II) --> Os(II) --> Fe(II) for (1)H, Fe(II) --> Ru(II) --> Os(II) for (15)N and bpy --> phen for both nuclei. The carbons are deshielded, the effect increasing in the order Ru(II) --> Os(II) --> Fe(II). Copyright (c) 2010 John Wiley & Sons, Ltd.

  18. Characterization and lead(II), cadmium(II), nickel(II) biosorption of dried marine brown macro algae Cystoseira barbata.

    PubMed

    Yalçın, Sibel; Sezer, Semih; Apak, Reşat

    2012-09-01

    The objectives of this research are to identify the functional groups and determine corresponding pK (a) values of the acidic sites on dried brown algae Cystoseira barbata using FTIR and potentiometric titrations, and to investigate the biosorption ability of biomass towards divalent nickel, cadmium, and lead ions. Adsorption was studied as a function of solution pH and contact time, and experimental data were evaluated by the Langmuir isotherm model. CaCl(2) pretreatment was applied to the sorbent for enhancing the metal uptake capacity. The effect of solution pH on biosorption equilibrium was investigated in the pH range of 1.5-5.0. Individual as well as competitive adsorption capacity of the sorbent were studied for metal cations and mixtures. The retention of the tested metal ions was mostly influenced from pH in the range of 1.5-2.5, then stayed almost constant up to 5.0, while Ni(II) uptake showed the highest variation with pH. Potentiometric titrations were performed to find the number of strong and weak acidic groups and their acidity constants. The density of strong and weak acidic functional groups in the biomass were found to be 0.9 and 2.26 mmol/g, respectively. The FTIR spectra of the sorbent samples indicated various functionalities on the biomass surface including carboxyl, hydroxyl, and amino and sulphonate groups which are responsible for the binding of metal ions. The capacity of the biomass for single metal ions (around 1 mmol/g) was increased to 1.3 mmol/g in competitive adsorption, Pb(II) showing the highest Langmuir intensity constant. Considering its extremely high abundance and low cost, C. barbata may be potentially important in metal ion removal from contaminated water and industrial effluents.

  19. [Ti II] and [Ni II] Emission from the Strontium Filament of eta Carinae

    NASA Technical Reports Server (NTRS)

    Bautista, M. A.; Hartman, H.; GUll, T. R.; Smith, N.; Lodders, K.

    2007-01-01

    We study the nature of the [Ti II] and [Ni II] emission from the so-called strontium filament found in the ejecta of eta Carinae. To this purpose we employ multilevel models of the Ti II and Ni II systems which are used to investigate the physical condition of the filament and the excitation mechanisms of the observed lines. For the Ti II ion, for which no atomic data was previously available, we carry out ab initio calculations of radiative transition rates and electron impact excitation rate coefficients. It is found that the observed spectrum is consistent with the lines being excited in a mostly neutral region with an electron density of the order of 10(exp 7) per cubic centimeter and a temperature around 6000 K. In analyzing three observations with different slit orientations recorded between March 2000 and November 2001 we find line ratios that change among various observations, in a way consistent with changes of up to an order of magnitude in the strength of the continuum radiation field. These changes result from different samplings of the extended filament, due to the different slit orientations used for each observation, and yield clues on the spatial extent and optical depth of the filament. The observed emission indicates a large Ti/Ni abundance ratio relative to solar abundances. It is suggested that the observed high Ti/Ni ratio in gas is caused by dust-gas fractionation processes and does not reflect the absolute Ti/Ni ratio in the ejecta of eta Carinae. We study the condensation chemistry of Ti, Ni and Fe within the filament and suggest that the observed gas phase overabundance of Ti is likely the result of selective photo-evaporation of Ti-bearing grains. Some mechanisms for such a scenario are proposed.

  20. LARGE-SCALE FLUCTUATIONS IN THE He II Ly{alpha} FOREST AND He II REIONIZATION

    SciTech Connect

    Furlanetto, Steven R.; Dixon, Keri L., E-mail: sfurlane@astro.ucla.ed

    2010-05-01

    We examine large-scale fluctuations in the He II Ly{alpha} forest transmission during and after He II reionization. We use a simple Monte Carlo model to distribute quasars throughout a large volume and compute the resulting radiation field along one-dimensional skewers. In agreement with previous studies, we find that the rarity of these sources induces order unity fluctuations in the mean optical depth after reionization, even when averaged over large segments ({approx}10-100Mpc across). We compare our models to existing data along five He II Ly{alpha} forest lines of sight spanning z {approx} 2-3.2. The large cosmic variance contained in our modelmore » plausibly explains many of the observed fluctuations at z {approx_lt} 2.5. But our models cannot accommodate the large fluctuations toward high optical depths on {approx}30Mpc scales observed at z {approx} 2.7-2.9, and the measured optical depths ({tau}{sub eff} {approx_gt} 4) at z>2.9 are difficult to explain with a smoothly evolving mean radiation field. In order to better understand these data, we construct a toy model of He II reionization, in which we assume that regions with the smallest radiation fields in a post-reionization universe (or farthest from strong ionizing sources) are completely dark during reionization. The observed fluctuations fit much more comfortably into this model, and we therefore argue that, according to present data, He II reionization does not complete until z {approx_lt} 2.9.« less

  1. Infalling Faint [O II] Emitters in Abell 851. II. Environment, Kinematics, and Star Formation History

    NASA Astrophysics Data System (ADS)

    Sato, Taro; Martin, Crystal L.

    2006-08-01

    We report on the local environment, kinematics, and star formation history of [O II]-selected objects in the z~0.4 galaxy cluster Abell 851, using Keck optical spectra. A large fraction (~55%) of cluster [O II] emitters show strong Balmer absorptions (>~4 Å in Hδ equivalent width). These e(a)-type spectra have been attributed to dusty starburst galaxies by Poggianti & Wu, an interpretation supported by our reddening measurements, which show a high frequency of very reddened [E(B-V)>~0.5] galaxies. Our spectral modeling requires starburst ages of <~1 Gyr, which is shorter than the cluster crossing timescale. We argue that this starburst phase occurs during cluster infall on the basis of the radial velocity distribution of the [O II] emitters, which present a deficit of systems near the cluster systemic velocity when compared to a virialized population (or a backsplash population). The spatial segregation of some redshifted and blueshifted groups strongly indicates that the accretion was recent. Throughout the cluster, the presence of [O II] emitters is strongly suppressed in dense environments. Our analysis supports previous suggestions that dusty starburst galaxies arise at the expense of gas-rich spiral galaxies [i.e., the e(c) type; Dressler and coworkers]. In addition, we describe a fainter population comprised largely of dwarf galaxies (Martin and coworkers) and find an even stronger suppression of [O II] emitters in high-density environments, indicative of more effective destruction by harassment and/or gas stripping. Comparison to previous morphological studies, limited to the cluster core, suggests that galaxy-galaxy interactions may trigger the starbursts. The high e(a) galaxy fraction in Abell 851 as compared to that in the field, however, suggests that some cluster-specific mechanism, likely related to the dynamical assembly of the cluster, also contributes to the high number of starbursts.

  2. Removal of Co(II), Cu(II) and Pb(II) ions by polymer based 2-hydroxyethyl methacrylate: thermodynamics and desorption studies

    PubMed Central

    2012-01-01

    Removal thermodynamics and desorption studies of some heavy metal ions such as Co(II), Cu(II) and Pb(II) by polymeric surfaces such as poly 2-hydroxyethyl methacrylate (PHEMA) and copolymer 2-hydroxyethyl methacrylate with monomer methyl methacrylate P(MMA-HEMA) as adsorbent surfaces from aqueous single solution were investigated with respect to the changes in pH of solution, adsorbent composition, contact time and temperature in the individual aqueous solution. The linear correlation coefficients of Langmuir and Freundlich isotherms were obtained and the results revealed that the Langmuir isotherm fitted the experiment results better than Freundlich isotherm. Using the Langmuir model equation, the monolayer removal capacity of PHEMA surface was found to be 0.7388, 0.8396 and 3.0367 mg/g for Co(II), Cu(ΙΙ) and Pb(II) ions and removal capacity of P(MMA-HEMA) was found to be 28.8442, 31.1526 and 31.4465 mg/g for Co(II), Cu(ΙΙ) and Pb(II) ions, respectively. Changes in the standard Gibbs free energy (ΔG0), standard enthalpy (ΔH0) and standard entropy (ΔS0) showed that the removals of mentioned ions onto PHEMA and P(MMA-HEMA) are spontaneous and exothermic at 293–323 K. The maximum desorption efficiency was 75.26% for Pb(II) using 0.100 M HNO3, 70.10% for Cu(II) using 0.100 M HCl, 59.20% for 0.100 M HCl 63.67% Co(II). PMID:23369255

  3. Silver(I), Mercury(II), Cadmium(II), and Zinc(II) Target Exposed Enzymic Iron-Sulfur Clusters when They Toxify Escherichia coli

    PubMed Central

    Xu, Fang Fang

    2012-01-01

    The toxicity of soft metals is of broad interest to microbiologists, both because such metals influence the community structures in natural environments and because several metals are used as antimicrobial agents. Their potency roughly parallels their thiophilicity, suggesting that their primary biological targets are likely to be enzymes that contain key sulfhydryl moieties. A recent study determined that copper poisons Escherichia coli in part by attacking the exposed [4Fe-4S] clusters of dehydratases. The present investigation sought to test whether other soft metals also target these enzymes. In vitro experiments revealed that low-micromolar concentrations of Ag(I) and Hg(II) directly inactivated purified fumarase A, a member of the dehydratase family. The enzyme was also poisoned by higher levels of Cd(II) and Zn(II), but it was unaffected by even millimolar concentrations of Mn(II), Co(II), Ni(II), and Pb(II). Electron paramagnetic resonance analysis and measurements of released iron confirmed that damage was associated with destruction of the [4Fe-4S] cluster, and indeed, the reconstruction of the cluster fully restored activity. Growth studies were then performed to test whether dehydratase damage might underlie toxicity in vivo. Barely toxic doses of Ag(I), Hg(II), Cd(II), and Zn(II) inactivated all tested members of the [4Fe-4S] dehydratase family. Again, activity was recovered when the clusters were rebuilt. The metals did not diminish the activities of other sampled enzymes, including NADH dehydrogenase I, an iron-sulfur protein whose clusters are shielded by polypeptide. Thus, the data indicate that dehydratases are damaged by the concentrations of metals that initiate bacteriostasis. PMID:22344668

  4. Elaborated studies for the ligitional behavior of thiouracil derivative towards Ni(II), Pd(II), Pt(IV), Cu(II) and UO2 ² ions.

    PubMed

    Abou-Melha, Khlood Saad

    2012-11-01

    A synthesis of new thiouracil derivative was carried out and deliberately investigated. A new series of complexes was prepared using Ni(II), Pd(II), Pt(IV), Cu(II) and UO(2)(+2) ions. IR spectral data proposed the coordination mod of the ligand towards each metal ion and displays the binegative pentadentate mod as the maximum mod of coordination obtained with Ni(II) and Cu(II) complexes. (1)HNMR spectrum of UO(2)(+2) complex in comparing with the free ligand spectrum supports the binegative appearance of the coordinated ligand through the ionization of CO and CS groups. The electronic spectral data as well as the magnetic moment measurements are coincide with each others to propose the square-planar geometry with Ni(II), Pd(II) and Cu(II) complexes and octahedral geometry with the others. ESR spectrum of Cu(II) complex displays axially symmetric g tensor parameters with g(11)>g(⊥)>2.0023 indicating that the [Formula: see text] orbital as a ground state with the square-planar geometry. The TG analysis for all isolated complexes were carried out to assert about the presence of water molecules physically or chemically attached with the central atom. The biological study was carried out against different microorganisms as gram negative, gram positive and fungi. The comparable data display the relative priority of Ni(II) complex in comparing with others against all organisms but, the other complexes display activity by the same with the free ligand. Copyright © 2012 Elsevier B.V. All rights reserved.

  5. Synthesis, characterization, DFT calculations and biological studies of Mn(II), Fe(II), Co(II) and Cd(II) complexes based on a tetradentate ONNO donor Schiff base ligand

    NASA Astrophysics Data System (ADS)

    Abdel-Rahman, Laila H.; Ismail, Nabawia M.; Ismael, Mohamed; Abu-Dief, Ahmed M.; Ahmed, Ebtehal Abdel-Hameed

    2017-04-01

    This study highlights synthesis and characterization of a tetradentate ONNO Schiff base ligand namely (1, 1‧- (pyridine-2, 3-dimethyliminomethyl) naphthalene-2, 2‧-diol) and hereafter denotes as "HNDAP″ and selected metal complexes including Mn(II), Fe(II), Co(II) and Cd(II) as a central metal. HNDAP was synthesized from 1:2 M ratio condensation of 2, 3-diaminopyridine and 2- hydroxy-1-naphthaldhyde, respectively. The stoichiometric ratios of the prepared complexes were estimated using complementary techniques such as; elemental analyses (-C, H, N), FT-IR, magnetic measurements and molar conductivity. Furthermore, their physicochemical studies were carried out using thermal TGA, DTA and kinetic-thermodynamic studies along with DFT calculations. The results of elemental analyses showed that these complexes are present in a 1:1 metal-to- ligand molar ratio. Moreover, the magnetic susceptibilities values at room temperature revealed that Mn(II), Fe(II) and Co(II) complexes are paramagnetic in nature and have an octahedral (Oh) geometry. In contrast, Cd(II) is diamagnetic and stabilizes in square planar sites. The molar conductivity measurements indicated that all complexes are nonelectrolytes in dimethyl formamide. Spectral data suggested that the ligand is as tetradentate and coordinated with Co(II) ion through two phenolic OH and two azomethine nitrogen. However, for Mn(II), Fe(II) and Cd(II) complexes, the coordination occurred through two phenolic oxygen and two azomethine nitrogen with deprotonation of OH groups. The proposed chemical structures have been validated by quantum mechanics calculations. Antimicrobial activities of both the HNDAP Schiff base ligand and its metal complexes were tested against strains of Gram (-ve) E. coli and Gram (+ve) B. subtilis and S. aureus bacteria and C. albicans, A. flavus and T. rubrum fungi. All the prepared compounds showed good results of inhibition against the selected pathogenic microorganisms. The investigated

  6. Kinetics of FeII-polyaminocarboxylate oxidation by molecular oxygen

    NASA Astrophysics Data System (ADS)

    Wilson, Jessica M.; Farley, Kevin J.; Carbonaro, Richard F.

    2018-03-01

    Complexation of iron by naturally-occurring and synthetic organic ligands has a large effect on iron oxidation and reduction rates which in turn affect the aqueous geochemistry of many other chemical constituents. In this study, the kinetics of FeII oxidation in the presence of the polyaminocarboxylate synthetic chelating agents ethylene glycol tetraacetic acid (EGTA) and trimethylenediamine-N,N,N‧,N‧-tetraacetic acid (TMDTA) was investigated over the pH range 5.50-8.53. Batch oxidation experiments in the presence of molecular oxygen were conducted using a 2:1 M concentration ratio of polyaminocarboxylate (ligand, L) to FeII. The experimental data resembled first order kinetics for the oxidation of FeII-L to FeIII-L and observed rate constants at pH 6.0 were comparable to rate constants for the oxidation of inorganic FeII. Similar to other structurally-similar FeII-polyaminocarboxylate complexes, oxidation rates of FeII-EGTA and FeII-TMDTA decrease with increasing pH, which is the opposite trend for the oxidation of FeII complexed with inorganic ligands. However, the oxidation rates of FeII complexed with EGTA and TMDTA were considerably lower (4-5 orders of magnitude) than FeII complexed to ethylenediaminetetraacetic acid (EDTA). The distinguishing feature of the slower-reacting complexes is that they have a longer backbone between diamine functional groups. An analytical equilibrium model was developed to determine the contributions of the species FeIIL2- and FeII(H)L- to the overall oxidation rate of FeII-L. Application of this model indicated that the protonated FeII(H)L species are more than three orders of magnitude more reactive than FeIIL2-. These rate constants were used in a coupled kinetic equilibrium numerical model where the ligand to iron ratio (TOTL:TOTFe) and pH were varied to evaluate the effect on the FeII oxidation rate. Overall, increasing TOTL:TOTFe for EGTA and TMDTA enhances FeII oxidation rates at lower pH and inhibits FeII oxidation

  7. Predictive value of the APACHE II, SAPS II, SOFA and GCS scoring systems in patients with severe purulent bacterial meningitis.

    PubMed

    Pietraszek-Grzywaczewska, Iwona; Bernas, Szymon; Łojko, Piotr; Piechota, Anna; Piechota, Mariusz

    2016-01-01

    Scoring systems in critical care patients are essential for predicting of the patient outcome and evaluating the therapy. In this study, we determined the value of the Acute Physiology and Chronic Health Evaluation II (APACHE II), Simplified Acute Physiology Score II (SAPS II), Sequential Organ Failure Assessment (SOFA) and Glasgow Coma Scale (GCS) scoring systems in the prediction of mortality in adult patients admitted to the intensive care unit (ICU) with severe purulent bacterial meningitis. We retrospectively analysed data from 98 adult patients with severe purulent bacterial meningitis who were admitted to the single ICU between March 2006 and September 2015. Univariate logistic regression identified the following risk factors of death in patients with severe purulent bacterial meningitis: APACHE II, SAPS II, SOFA, and GCS scores, and the lengths of ICU stay and hospital stay. The independent risk factors of patient death in multivariate analysis were the SAPS II score, the length of ICU stay and the length of hospital stay. In the prediction of mortality according to the area under the curve, the SAPS II score had the highest accuracy followed by the APACHE II, GCS and SOFA scores. For the prediction of mortality in a patient with severe purulent bacterial meningitis, SAPS II had the highest accuracy.

  8. Solid phase selective separation and preconcentration of Cu(II) by Cu(II)-imprinted polymethacrylic microbeads.

    PubMed

    Dakova, Ivanka; Karadjova, Irina; Ivanov, Ivo; Georgieva, Ventsislava; Evtimova, Bisera; Georgiev, George

    2007-02-12

    Ion-imprinted polymer (IIP) particles are prepared by copolymerization of methacrylic acid as monomer, trimethylolpropane trimethacrylate as crosslinking agent and 2,2'-azo-bis-isobutyronitrile as initiator in the presence of Cu(II), a Cu(II)-4-(2-pyridylazo)resorcinol (Cu(II)-PAR) complex, and PAR only. A batch procedure is used for the determination of the characteristics of the Cu(II) solid phase extraction from the IIP produced. The results obtained show that the Cu(II)-PAR IIP has the greatest adsorption capacity (37.4 micromol g(-1) of dry copolymer) among the IIPs investigated. The optimal pH value for the quantitative preconcentration is 7, and full desorption is achieved by 1 M HNO(3). The selectivity coefficients (S(Cu/Me)) for Me=Ni(II), Co(II) are 45.0 and 38.5, respectively. It is established that Cu(II)-PAR IIPs can be used repeatedly without a considerable adsorption capacity loss. The determination of Cu(II) ions in seawater shows that the interfering matrix does not influence the preconcentration and selectivity values of the Cu(II)-PAR IIPs. The detection and quantification limits are 0.001 micromol L(-1) (3sigma) and 0.003 micromol L(-1) (6sigma), respectively.

  9. Biosorption of Fe(II) and Mn(II) Ions from Aqueous Solution by Rice Husk Ash

    PubMed Central

    Zhao, Jiaying; Jiang, Zhao; Shan, Dexin; Lu, Yan

    2014-01-01

    Rice husk ash (RHA), an agricultural waste, was used as biosorbent for the removal of Iron(II) and Manganese(II) ions from aqueous solutions. The structural and morphological characteristics of RHA and its elemental compositions before and after adsorption of Fe(II) and Mn(II) were determined by scanning electron microscopic (SEM) and X-ray fluorescence (XRF) analyses. Batch experiments were carried out to determine the influence of initial pH, contact time, adsorbent dosage, and initial concentration on the removal of Fe(II) and Mn(II) ions. Langmuir, Freundlich, and Dubinin-Radushkevich (D-R) models were applied to describe the biosorption isotherm of the metal ions by RHA. The correlation coefficient (R 2) of Langmuir and Freundlich isotherm models equals 0.995 and 0.901 for Fe(II), 0.9862 and 0.8924 for Mn(II), respectively, so the Langmuir model fitted the equilibrium data better than the Freundlich isotherm model. The mean free energy values evaluated from the D-R model indicated that the biosorption of Fe(II) and Mn(II) onto RHA was physical in nature. Experimental data also showed that the biosorption processes of both metal ions complied with the pseudo-second-order kinetics. PMID:24982918

  10. Probing HeII Reionization at z>3.5 with Resolved HeII Lyman Alpha Forest Spectra

    NASA Astrophysics Data System (ADS)

    Worseck, Gabor

    2017-08-01

    The advent of GALEX and COS have revolutionized our view of HeII reionization, the final major phase transition of the intergalactic medium. COS spectra of the HeII Lyman alpha forest have confirmed with high confidence the high HeII transmission that signifies the completion of HeII reionization at z 2.7. However, the handful of z>3.5 quasars observed to date show a set of HeII transmission 'spikes' and larger regions with non-zero transmission that suggest HeII reionization was well underway by z=4. This is in striking conflict with predictions from state-of-the-art radiative transfer simulations of a HeII reionization driven by bright quasars. Explaining these measurements may require either faint quasars or more exotic sources of hard photons at z>4, with concomitant implications for HI reionization. However, many of the observed spikes are unresolved in G140L spectra and are significantly impacted by Poisson noise. Current data cannot reliably probe the ionization state of helium at z>3.5.We request 41 orbits to obtain science-grade G130M spectra of the two UV-brightest HeII-transmitting QSOs at z>3.5 to confirm and resolve their HeII transmission spikes as an unequivocal test of early HeII reionization. These spectra are complemented by recently obtained data from 8m telescopes: (1) Echelle spectra of the coeval HI Lya forest to map the underlying density field that modulates the HeII absorption, and (2) Our dedicated survey for foreground QSOs that may source the HeII transmission. Our recent HST programs revealed the only two viable targets to resolve the z>3.5 HeII Lyman alpha forest, and to conclusively solve this riddle.

  11. Type-II Symmetry-Protected Topological Dirac Semimetals

    NASA Astrophysics Data System (ADS)

    Chang, Tay-Rong; Xu, Su-Yang; Sanchez, Daniel S.; Tsai, Wei-Feng; Huang, Shin-Ming; Chang, Guoqing; Hsu, Chuang-Han; Bian, Guang; Belopolski, Ilya; Yu, Zhi-Ming; Yang, Shengyuan A.; Neupert, Titus; Jeng, Horng-Tay; Lin, Hsin; Hasan, M. Zahid

    2017-07-01

    The recent proposal of the type-II Weyl semimetal state has attracted significant interest. In this Letter, we propose the concept of the three-dimensional type-II Dirac fermion and theoretically identify this new symmetry-protected topological state in the large family of transition-metal icosagenides, M A3 (M =V , Nb, Ta; A =Al , Ga, In). We show that the VAl3 family features a pair of strongly Lorentz-violating type-II Dirac nodes and that each Dirac node can be split into four type-II Weyl nodes with chiral charge ±1 via symmetry breaking. Furthermore, we predict that the Landau level spectrum arising from the type-II Dirac fermions in VAl3 is distinct from that of known Dirac or Weyl semimetals. We also demonstrate a topological phase transition from a type-II Dirac semimetal to a quadratic Weyl semimetal or a topological crystalline insulator via crystalline distortions.

  12. The Southern H ii Region Discovery Survey (SHRDS): Pilot Survey

    SciTech Connect

    Brown, C.; Dickey, John M.; Jordan, C.

    2017-07-01

    The Southern H ii Region Discovery Survey is a survey of the third and fourth quadrants of the Galactic plane that will detect radio recombination line (RRL) and continuum emission at cm-wavelengths from several hundred H ii region candidates using the Australia Telescope Compact Array. The targets for this survey come from the WISE Catalog of Galactic H ii Regions and were identified based on mid-infrared and radio continuum emission. In this pilot project, two different configurations of the Compact Array Broad Band receiver and spectrometer system were used for short test observations. The pilot surveys detected RRL emission frommore » 36 of 53 H ii region candidates, as well as seven known H ii regions that were included for calibration. These 36 recombination line detections confirm that the candidates are true H ii regions and allow us to estimate their distances.« less

  13. Cephalic angiotensin receptors mediating drinking to systemic angiotensin II.

    PubMed

    Johnson, A K; Schwob, J E

    1975-01-01

    In rats implanted with cannulae to allow delivery of solutions to the cerebral ventricular system, pretreatment with 5 mug or 0.5 mug of saralasin acetate (Sar1 Ala8 Angiotensin II), an angiotensin II competitive analog, significantly attenuated drinking to subcutaneous (SC) injections of 500 mug of angiotensin II. However, pretreatment with either SC (5 mug or 20 mug) or with intravenous (5 mug) saralasin had no effect on drinking to SC angiotensin II (500 mug). Intracranial (IC) injections of 5 mug of saralasin had no effect on drinking in response to SC injections of 0.8 cc of a 10 percent NaCl solution and did not attenuate ingestion of a milk solution in a dessert test. On the basis of the specificity and the greater efficacy shown by IC saralasin in attenuating drinking to systemically applied angiotensin II, it was concluded that circulating angiotensin II reaches brain periventricular receptors which mediate drinking.

  14. Lidar conversion parameters derived from SAGE II extinction measurements

    NASA Technical Reports Server (NTRS)

    Thomason, L. W.; Osborn, M. T.

    1992-01-01

    SAGE II multiwavelength aerosol extinction measurements are used to estimate mass- and extinction-to-backscatter conversion parameters. The basis of the analysis is the principal component analysis of the SAGE II extinction kernels to estimate both total aerosol mass and aerosol backscatter at a variety of wavelengths. Comparisons of coincident SAGE II extinction profiles with 0.694-micron aerosol backscatter profiles demonstrate the validity of the method.

  15. Temperature gradients and chemical abundances in H II regions

    NASA Astrophysics Data System (ADS)

    Arellano-Córdova, K. Z.; Rodríguez, M.; Delgado-Inglada, G.

    2017-07-01

    We have collected a sample of 112 H II regions with measurements of Te[N II] and Te[O III] to study the effect of using relations between these two temperatures in the determination of oxygen abundances. The results confirm that the temperature relation depends on the degree of ionization of the H II regions. We propose new temperature relations that consider this dependence and lead to better estimates of electron temperatures and oxygen abundances.

  16. Documentation of angiotensin II receptors in glomerular epithelial cells

    NASA Technical Reports Server (NTRS)

    Sharma, M.; Sharma, R.; Greene, A. S.; McCarthy, E. T.; Savin, V. J.; Cowley, A. W. (Principal Investigator)

    1998-01-01

    Angiotensin II decreases glomerular filtration rate, renal plasma flow, and glomerular capillary hydraulic conductivity. Although angiotensin II receptors have been demonstrated in mesangial cells and proximal tubule cells, the presence of angiotensin II receptors in glomerular epithelial cells has not previously been shown. Previously, we have reported that angiotensin II caused an accumulation of cAMP and a reorganization of the actin cytoskeleton in cultured glomerular epithelial cells. Current studies were conducted to verify the presence of angiotensin II receptors by immunological and non-peptide receptor ligand binding techniques and to ascertain the activation of intracellular signal transduction in glomerular epithelial cells in response to angiotensin II. Confluent monolayer cultures of glomerular epithelial cells were incubated with angiotensin II, with or without losartan and/or PD-123,319 in the medium. Membrane vesicle preparations were obtained by homogenization of washed cells followed by centrifugation. Sodium dodecyl sulfate-polyacrylamide gel electrophoresis of membrane proteins followed by multiscreen immunoblotting was used to determine the presence of angiotensin II receptor type 1 (AT1) or type 2 (AT2). Angiotensin II-mediated signal transduction in glomerular epithelial cells was studied by measuring the levels of cAMP, using radioimmunoassay. Results obtained in these experiments showed the presence of both AT1 and AT2 receptor types in glomerular epithelial cells. Angiotensin II was found to cause an accumulation of cAMP in glomerular epithelial cells, which could be prevented only by simultaneous use of losartan and PD-123,319, antagonists for AT1 and AT2, respectively. The presence of both AT1 and AT2 receptors and an increase in cAMP indicate that glomerular epithelial cells respond to angiotensin II in a manner distinct from that of mesangial cells or proximal tubular epithelial cells. Our results suggest that glomerular epithelial

  17. Heparin cofactor II-dependent antithrombin activity of calcium spirulan.

    PubMed

    Hayakawa, Y; Hayashi, T; Hayashi, K; Hayashi, T; Ozawa, T; Niiya, K; Sakuragawa, N

    1996-07-01

    Calcium spirulan (Ca-SP), a novel sulfated polysaccharide isolated from the blue-green alga Spirulina platensis, enhanced the antithrombin activity of heparin cofactor II (HC II) more than 10000-fold. The apparent second-order rate constant of thrombin inhibition by HC II was calculated to be 4.2 x 10(4) M-1 min-1 in the absence of Ca-SP, and it increased in the presence of 50 micrograms/ml Ca-SP to 4.5 x 10(8) M-1 min-1. Ca-SP effectively induced the formation of a thrombin-HC II complex in plasma. In the presence of Ca-SP, both the recombinant HC II variants Lys173-->Leu and Arg 189-->His, which are defective in interactions with heparin and dermatan sulfate, respectively, inhibited thrombin in a manner similar to native rHC II. This result indicates that the binding site of HC II for Ca-SP is different from the heparin- or dermatan sulfate-binding site. When we removed the calcium from the Ca-SP, the compound did not exert any antithrombin activity. Furthermore, Na-SP, which was prepared by replacement of the calcium in Ca-SP with sodium, accelerated the antithrombin activity of HC II as Ca-SP did. We therefore suggest that the molecular conformation maintained by Ca or Na is indispensable to the antithrombin activity of Ca-SP. The HC II-dependent antithrombin activity of Ca-SP was almost totally abolished by treatment with chondroitinase AC I, heparinase or heparitinase, but not by treatment with chondroitinase ABC and chondroitinase AC II, suggesting that a heparin- or dermatan sulfate-like structure is not responsible for the activation of HC II by Ca-SP. Ca-SP is therefore thought to be a unique sulfated polysaccharide which shows a strong antithrombin effect in an exclusively HC II-dependent manner.

  18. A high resolution atlas of Mg II profiles

    NASA Technical Reports Server (NTRS)

    Ewald, R.; Nichols-Bohlin, Joy Y.; Kondo, Yoji

    1990-01-01

    An atlas of high dispersion Mg II profiles for standard stars of spectral types B0 through G9 is presented. The atlas contains plots of the Mg II profiles for approximately 65 stars and associated equivalent width measurements for both absorption and emission components, and the subordinate lines. The atlas is used to investigate systematic behavior of the Mg II profiles and correlation of the behavior with spectral classification.

  19. Finite State Machines and Modal Models in Ptolemy II

    DTIC Science & Technology

    2009-11-01

    Finite State Machines and Modal Models in Ptolemy II Edward A. Lee Electrical Engineering and Computer Sciences University of California at Berkeley...DATES COVERED 00-00-2009 to 00-00-2009 4. TITLE AND SUBTITLE Finite State Machines and Modal Models in Ptolemy II 5a. CONTRACT NUMBER 5b...describes the usage and semantics of finite-state machines (FSMs) and modal models in Ptolemy II. FSMs are actors whose behavior is described using a

  20. 49 CFR 172.438 - RADIOACTIVE YELLOW-II label.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false RADIOACTIVE YELLOW-II label. 172.438 Section 172... REQUIREMENTS, AND SECURITY PLANS Labeling § 172.438 RADIOACTIVE YELLOW-II label. (a) Except for size and color, the RADIOACTIVE YELLOW-II must be as follows: EC02MR91.033 (b) In addition to complying with § 172.407...

  1. 49 CFR 172.438 - RADIOACTIVE YELLOW-II label.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 2 2012-10-01 2012-10-01 false RADIOACTIVE YELLOW-II label. 172.438 Section 172... REQUIREMENTS, AND SECURITY PLANS Labeling § 172.438 RADIOACTIVE YELLOW-II label. (a) Except for size and color, the RADIOACTIVE YELLOW-II must be as follows: EC02MR91.033 (b) In addition to complying with § 172.407...

  2. 49 CFR 172.438 - RADIOACTIVE YELLOW-II label.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 2 2011-10-01 2011-10-01 false RADIOACTIVE YELLOW-II label. 172.438 Section 172... REQUIREMENTS, AND SECURITY PLANS Labeling § 172.438 RADIOACTIVE YELLOW-II label. (a) Except for size and color, the RADIOACTIVE YELLOW-II must be as follows: EC02MR91.033 (b) In addition to complying with § 172.407...

  3. 49 CFR 172.438 - RADIOACTIVE YELLOW-II label.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 2 2013-10-01 2013-10-01 false RADIOACTIVE YELLOW-II label. 172.438 Section 172... REQUIREMENTS, AND SECURITY PLANS Labeling § 172.438 RADIOACTIVE YELLOW-II label. (a) Except for size and color, the RADIOACTIVE YELLOW-II must be as follows: EC02MR91.033 (b) In addition to complying with § 172.407...

  4. 49 CFR 172.438 - RADIOACTIVE YELLOW-II label.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 2 2014-10-01 2014-10-01 false RADIOACTIVE YELLOW-II label. 172.438 Section 172... REQUIREMENTS, AND SECURITY PLANS Labeling § 172.438 RADIOACTIVE YELLOW-II label. (a) Except for size and color, the RADIOACTIVE YELLOW-II must be as follows: EC02MR91.033 (b) In addition to complying with § 172.407...

  5. TAMDAR Sensor Validation in 2003 AIRS II

    NASA Technical Reports Server (NTRS)

    Daniels, Taumi S.; Murray, John J.; Anderson, Mark V.; Mulally, Daniel J.; Jensen, Kristopher R.; Grainger, Cedric A.; Delene, David J.

    2005-01-01

    This study entails an assessment of TAMDAR in situ temperature, relative humidity and winds sensor data from seven flights of the UND Citation II. These data are undergoing rigorous assessment to determine their viability to significantly augment domestic Meteorological Data Communications Reporting System (MDCRS) and the international Aircraft Meteorological Data Reporting (AMDAR) system observational databases to improve the performance of regional and global numerical weather prediction models. NASA Langley Research Center participated in the Second Alliance Icing Research Study from November 17 to December 17, 2003. TAMDAR data taken during this period is compared with validation data from the UND Citation. The data indicate acceptable performance of the TAMDAR sensor when compared to measurements from the UND Citation research instruments.

  6. Apple II PASCAL programs for molecular biologists.

    PubMed Central

    Malthiery, B; Bellon, B; Giorgi, D; Jacq, B

    1984-01-01

    A collection of PASCAL programs designed for the Apple II microcomputer is presented. These DNA sequence handling and analysis programs are interactive and may be used even by people with no computer experience. The package allows the user to enter a sequence from the keyboard, to modify it, to generate the reverse complement, to create new sequences from parts of other ones, to display or print sequences in various formats. Some analysis tasks are also performed: Translation, searches for restriction sites, for homology with subsequences, either perfect or with an adjustable match percentage. In addition, two programs are also included: The first one allows DNA data sequences generated with a BASIC program under the CP/M operating system to be used with these PASCAL programs. The second one is designed for the automatic assembly of DNA fragments sequences, obtained with the GILBERT-MAXAM or M13 techniques, into a complete sequence. PMID:6320099

  7. Robotic dry stripping of airframes - Phase II

    NASA Astrophysics Data System (ADS)

    Pauli, Robert A.; Wittenberg, Art M.

    1989-03-01

    This paper describes a program for the development of a dust-free closed-cycle robotic system for dry stripping of airframes, designed to insure dust-free work environment and reduce plastic-media loss, the contamination risk, and the media inventory requirement. Phase I of the program involved building a prototype of the proposed robotic arm and its dust enclosure to prove basic automation concepts, showing reasonable paint removal rate from a curved surface, and establishing that the process is dust-free and recovers plastic media in a closed-cycle fashion. This paper contains calculations on the effect of different blasting parameters in order to determine optimum values required for the completion of Phase I. Also presented is the progress achieved by the Phase II of the program, which is to prove the total concept by building the complete system and demonstrating its capability.

  8. [Orthodontic failures in Class II cases].

    PubMed

    Boileau, Marie-José

    2016-03-01

    In Class II treatment, as with all malformations, therapeutic failure can impact some or all of our treatment aims, whether occlusal, functional or esthetic. Using clinical cases, we will first define the concept of failure and the limits of what is acceptable in these different areas. We will then attempt to determine the main causes underlying our failures in order to better avoid them. An analysis of the literature and of the clinical cases demonstrates that our failures are most often caused by a misevaluation of the amount and direction of residual growth, poor control of the vertical dimension, inadequate management of functional problems, an inadequate position of the maxillary and mandibular incisors. In addition to these major treatment errors, one also encounters insufficient patient cooperation, which needs to be assessed and maintained in order to limit the number of failures and treatment drop-outs. © EDP Sciences, SFODF, 2016.

  9. Delta II JPSS-1 Prelaunch Press Conference

    NASA Image and Video Library

    2017-11-12

    At Vandenberg Air Force Base in California, U. S. Air Force Capt. Ross Malugani, launch weather officer at Vandenberg's 30th Space Wing, speaks to members of the media at a prelaunch news conference for the Joint Polar Satellite System-1, or JPSS-1. Built by Ball Aerospace and Technologies Corp. of Boulder, Colorado, JPSS is the first in a series four next-generation environmental satellites in a collaborative program between the NOAA and NASA. Liftoff atop a United Launch Alliance Delta II rocket is scheduled to take place from Vandenberg's Space Launch Complex 2 at 1:47 a.m. PST (4:47 a.m. EST), on Nov. 14, 2017.

  10. Combined Final Report for Colony II Project

    SciTech Connect

    Kale, Laxmikant; Jones, Terry; Moreira, Jose

    2013-10-23

    (This report was originally submmited by the lead PI (Terry Jones, ORNL) on October 22, 2013 to the program manager, Lucy Nowell. It is being submitted from University of Illinois in accordance with instructions). HPC Colony II seeks to provide portable performance for leadership class machines. Our strategy is based on adaptive system software that aims to make the intelligent decisions necessary to allow domain scientists to safely focus on their task at hand and allow the system software stack to adapt their application to the underlying architecture. This report describes the research undertaken towards these objectives and the resultsmore » obtained over the performance period of the project.« less

  11. Delta II THEMIS Pre-Launch

    NASA Image and Video Library

    2002-01-01

    In this close-up aerial view, the Delta II rocket with the THEMIS spacecraft atop sits ready for launch on Pad 17-B at Cape Canaveral Air Force Station as the mobile service tower begins to move away. THEMIS, an acronym for Time History of Events and Macroscale Interactions during Substorms, consists of five identical probes that will track violent, colorful eruptions near the North Pole. This will be the largest number of scientific satellites NASA has ever launched into orbit aboard a single rocket. The THEMIS mission aims to unravel the mystery behind auroral substorms, an avalanche of magnetic energy powered by the solar wind that intensifies the northern and southern lights. The mission will investigate what causes auroras in the Earth’s atmosphere to dramatically change from slowly shimmering waves of light to wildly shifting streaks of bright color. Launch is scheduled for 6:05 p.m.

  12. Delta II THEMIS Pre-Launch

    NASA Image and Video Library

    2002-01-01

    The Delta II rocket with the THEMIS spacecraft atop sits ready for launch on Pad 17-B at Cape Canaveral Air Force Station in this aerial view of the launch complex area as the mobile service tower begins to move away. THEMIS, an acronym for Time History of Events and Macroscale Interactions during Substorms, consists of five identical probes that will track violent, colorful eruptions near the North Pole. This will be the largest number of scientific satellites NASA has ever launched into orbit aboard a single rocket. The THEMIS mission aims to unravel the mystery behind auroral substorms, an avalanche of magnetic energy powered by the solar wind that intensifies the northern and southern lights. The mission will investigate what causes auroras in the Earth’s atmosphere to dramatically change from slowly shimmering waves of light to wildly shifting streaks of bright color. Launch is scheduled for 6:05 p.m.

  13. Delta II THEMIS Pre-Launch

    NASA Image and Video Library

    2002-01-01

    In this close-up aerial view, the Delta II rocket with the THEMIS spacecraft atop sits ready for launch on Pad 17-B at Cape Canaveral Air Force Station. THEMIS, an acronym for Time History of Events and Macroscale Interactions during Substorms, consists of five identical probes that will track violent, colorful eruptions near the North Pole. This will be the largest number of scientific satellites NASA has ever launched into orbit aboard a single rocket. The THEMIS mission aims to unravel the mystery behind auroral substorms, an avalanche of magnetic energy powered by the solar wind that intensifies the northern and southern lights. The mission will investigate what causes auroras in the Earth’s atmosphere to dramatically change from slowly shimmering waves of light to wildly shifting streaks of bright color. Launch is scheduled for 6:05 p.m.

  14. Delta II THEMIS Pre-Launch

    NASA Image and Video Library

    2002-01-01

    In this aerial view, the Delta II rocket with the THEMIS spacecraft sits ready for launch on Pad 17-B at Cape Canaveral Air Force Station, as the mobile service tower moves away from the pad. THEMIS, an acronym for Time History of Events and Macroscale Interactions during Substorms, consists of five identical probes that will track violent, colorful eruptions near the North Pole. This will be the largest number of scientific satellites NASA has ever launched into orbit aboard a single rocket. The THEMIS mission aims to unravel the mystery behind auroral substorms, an avalanche of magnetic energy powered by the solar wind that intensifies the northern and southern lights. The mission will investigate what causes auroras in the Earth’s atmosphere to dramatically change from slowly shimmering waves of light to wildly shifting streaks of bright color. Launch is scheduled for 6:05 p.m.

  15. Delta II THEMIS Pre-Launch

    NASA Image and Video Library

    2002-01-01

    In this close-up aerial view, the Delta II rocket with the THEMIS spacecraft atop sits ready for launch on Pad 17-B at Cape Canaveral Air Force Station as the mobile service tower moves away from the pad. THEMIS, an acronym for Time History of Events and Macroscale Interactions during Substorms, consists of five identical probes that will track violent, colorful eruptions near the North Pole. This will be the largest number of scientific satellites NASA has ever launched into orbit aboard a single rocket. The THEMIS mission aims to unravel the mystery behind auroral substorms, an avalanche of magnetic energy powered by the solar wind that intensifies the northern and southern lights. The mission will investigate what causes auroras in the Earth’s atmosphere to dramatically change from slowly shimmering waves of light to wildly shifting streaks of bright color. Launch is scheduled for 6:05 p.m.

  16. Delta II - SIRTF Lift and Mate

    NASA Image and Video Library

    2003-07-28

    Seen from below inside the mobile service tower on Launch Complex 17-B, Cape Canaveral Air Force Station, the second stage of the Delta II Heavy rocket is being lowered toward the first stage for mating. The rocket will launch the Space Infrared Telescope Facility (SIRTF), currently scheduled for mid-August. SIRTF consists of three cryogenically cooled science instruments and an 0.85-meter telescope, and is one of NASA's largest infrared telescopes to be launched. SIRTF will obtain images and spectra by detecting the infrared energy, or heat, radiated by objects in space. Most of this infrared radiation is blocked by the Earth's atmosphere and cannot be observed from the ground.

  17. Delta II SIRTF Booster Lift & Mate

    NASA Image and Video Library

    2003-03-05

    One of nine solid rocket boosters is lifted on Launch Complex 17-B, Cape Canaveral Air Force Station, for mating with the Delta II rocket in the background. The second stage will later be hoisted atop the first stage. The Delta rocket is the launch vehicle for the Space Infrared Telescope Facility. SIRTF will obtain images and spectra by detecting the infrared energy, or heat, radiated by objects in space. Most of this infrared radiation is blocked by the Earth's atmosphere and cannot be observed from the ground. Consisting of an 0.85-meter telescope and three cryogenically cooled science instruments, SIRTF is one of NASA's largest infrared telescopes to be launched. SIRTF is scheduled for launch April 15 at 4:34:07 a.m. EDT.

  18. Delta II JPSS-1 Prelaunch Press Conference

    NASA Image and Video Library

    2017-11-12

    At Vandenberg Air Force Base in California, NASA and industry leaders speak to members of the media at a prelaunch news conference for the Joint Polar Satellite System-1, or JPSS-1. Participants, from left, are Steve Volz, director of NOAA’s Satellite and Information Service, Greg Mandt, director of the NOAA Joint Polar Satellite System Program, Sandra Smalley, director of the Joint Agency Satellite Division at NASA Headquarters, Omar Baez, NASA launch director, and Scott Messer, United Launch Alliance program manager for NASA missions. Built by Ball Aerospace and Technologies Corp. of Boulder, Colorado, JPSS is the first in a series four next-generation environmental satellites in a collaborative program between the NOAA and NASA. Liftoff atop a United Launch Alliance Delta II rocket is scheduled to take place from Vandenberg's Space Launch Complex 2 at 1:47 a.m. PST (4:47 a.m. EST), on Nov. 14, 2017.

  19. Delta II JPSS-1 Prelaunch Press Conference

    NASA Image and Video Library

    2017-11-12

    At Vandenberg Air Force Base in California, NASA and industry leaders speak to members of the media at a prelaunch news conference for the Joint Polar Satellite System-1, or JPSS-1. Participants, from left, are Sandra Smalley, director of the Joint Agency Satellite Division at NASA Headquarters, Omar Baez, NASA launch director, and Scott Messer, United Launch Alliance program manager for NASA missions. Built by Ball Aerospace and Technologies Corp. of Boulder, Colorado, JPSS is the first in a series four next-generation environmental satellites in a collaborative program between the NOAA and NASA. Liftoff atop a United Launch Alliance Delta II rocket is scheduled to take place from Vandenberg's Space Launch Complex 2 at 1:47 a.m. PST (4:47 a.m. EST), on Nov. 14, 2017.

  20. Delta II JPSS-1 Prelaunch Press Conference

    NASA Image and Video Library

    2017-11-12

    Vandenberg Air Force Base in California, NASA and industry leaders speak to members of the media at a prelaunch news conference for the Joint Polar Satellite System-1, or JPSS-1. Participants, from left, are Greg Mandt, director of the NOAA Joint Polar Satellite System Program, Sandra Smalley, director of the Joint Agency Satellite Division at NASA Headquarters, Omar Baez, NASA launch director, Scott Messer, United Launch Alliance program manager for NASA missions, and U. S. Air Force Capt. Ross Malugani, launch weather officer at Vandenberg's 30th Space Wing. Built by Ball Aerospace and Technologies Corp. of Boulder, Colorado, JPSS is the first in a series four next-generation environmental satellites in a collaborative program between the NOAA and NASA. Liftoff atop a United Launch Alliance Delta II rocket is scheduled to take place from Vandenberg's Space Launch Complex 2 at 1:47 a.m. PST (4:47 a.m. EST), on Nov. 14, 2017.

  1. Delta II JPSS-1 Prelaunch Press Conference

    NASA Image and Video Library

    2017-11-12

    At Vandenberg Air Force Base in California, NASA and industry leaders speak to members of the media at a prelaunch news conference for the Joint Polar Satellite System-1, or JPSS-1. Participants, from left, are Steve Volz, director of NOAA’s Satellite and Information Service, and Greg Mandt, director of the NOAA Joint Polar Satellite System Program. Built by Ball Aerospace and Technologies Corp. of Boulder, Colorado, JPSS is the first in a series four next-generation environmental satellites in a collaborative program between the NOAA and NASA. Liftoff atop a United Launch Alliance Delta II rocket is scheduled to take place from Vandenberg's Space Launch Complex 2 at 1:47 a.m. PST (4:47 a.m. EST), on Nov. 14, 2017.

  2. Delta II JPSS-1 Prelaunch Press Conference

    NASA Image and Video Library

    2017-11-12

    At Vandenberg Air Force Base in California, NASA and industry leaders speak to members of the media at a prelaunch news conference for the Joint Polar Satellite System-1, or JPSS-1. Participants, from left, are Steve Volz, director of NOAA’s Satellite and Information Service, Greg Mandt, director of the NOAA Joint Polar Satellite System Program, and Sandra Smalley, director of the Joint Agency Satellite Division at NASA Headquarters. Built by Ball Aerospace and Technologies Corp. of Boulder, Colorado, JPSS is the first in a series four next-generation environmental satellites in a collaborative program between the NOAA and NASA. Liftoff atop a United Launch Alliance Delta II rocket is scheduled to take place from Vandenberg's Space Launch Complex 2 at 1:47 a.m. PST (4:47 a.m. EST), on Nov. 14, 2017.

  3. Atlas of Comet Halley 1910 II

    NASA Technical Reports Server (NTRS)

    Brandt, J. C.; Donn, B.

    1986-01-01

    An Atlas of Comet Halley 1910 II photographs and spectra is being prepared. The major section consists of 838 photographic observations from fifteen observatories around the world. Multiple images of many photographs are reproduced to bring out detail in the near nucleus region, in the coma and in the tail. The Atlas contains a total of 1209 photographic images of the 1910 apparition. In addition there are sections showing drawings from 1935 and 1910. A short section compares 1910 drawings and photographs. The final two sections display digitally processed images from 1910 and 1910 spectra. A three part appendix contains diagrams of various data associated with the 1910 apparition, a set of tables of all 1910 images and a bibliography.

  4. Development of hearing. Part II. Embryology.

    PubMed

    Peck, J E

    1994-11-01

    We humans hear the way we do because of at least three major forces. The first is phylogeny, the evolutionary changes in the auditory system since its beginnings. Another is embryology, the development of the system in each individual. Finally, there is the biologically determined mechanism we are born with and our interaction with the environment in early postnatal life. This series of articles reviews each aspect so that we may have a fuller appreciation of how it is we come to hear the way we do. Part I described the phylogeny of the auditory system. Part II traces the development in prenatal life of the internal, middle, and external ear and the nervous system by days, weeks, and months. Wherever possible, parallels are drawn between phylogenetic and embryologic development. Part III considers the postnatal aspects of auditory development.

  5. Delta II MER-A Spirit Launch

    NASA Image and Video Library

    2003-06-11

    Amid billows of smoke and steam, the Delta II rocket with its Mars Exploration Rover (MER-A) payload lifts off the pad on time at 1:58 p.m. EDT from Launch Complex 17-A, Cape Canaveral Air Force Station. MER-A, known as "Spirit," is the first of two rovers being launched to Mars. When the two rovers arrive at the red planet in 2004, they will bounce to airbag-cushioned landings at sites offering a balance of favorable conditions for safe landings and interesting science. The rovers see sharper images, can explore farther and examine rocks better than anything that has ever landed on Mars. The designated site for the MER-A mission is Gusev Crater, which appears to have been a crater lake. The second rover, MER-B, is scheduled to launch June 25.

  6. Delta II MER-A Spirit Launch

    NASA Image and Video Library

    2003-06-10

    As if perched on top of a candle, the Mars Exploration Rover known as “Spirit” is hurled into space on a Delta II rocket. Liftoff occurred on time at 1:58 p.m. EDT from Launch Complex 17-A, Cape Canaveral Air Force Station. MER-A is the first of two rovers being launched to Mars. When the two rovers arrive at the red planet in 2004, they will bounce to airbag-cushioned landings at sites offering a balance of favorable conditions for safe landings and interesting science. The rovers see sharper images, can explore farther and examine rocks better than anything that has ever landed on Mars. The designated site for the MER-A mission is Gusev Crater, which appears to have been a crater lake. The second rover, MER-B, is scheduled to launch June 25.

  7. Delta II MER-A Spirit Launch

    NASA Image and Video Library

    2003-06-10

    The Delta II rocket with its Mars Exploration Rover (MER-A) payload leaps from the smoke and steam below into space. Liftoff occurred on time at 1:58 p.m. EDT from Launch Complex 17-A, Cape Canaveral Air Force Station. MER-A, known as "Spirit," is the first of two rovers being launched to Mars. When the two rovers arrive at the red planet in 2004, they will bounce to airbag-cushioned landings at sites offering a balance of favorable conditions for safe landings and interesting science. The rovers see sharper images, can explore farther and examine rocks better than anything that has ever landed on Mars. The designated site for the MER-A mission is Gusev Crater, which appears to have been a crater lake. The second rover, MER-B, is scheduled to launch June 25.

  8. Delta II MER-A Spirit Launch

    NASA Image and Video Library

    2003-06-10

    A trail of smoke is all that identifies the Delta II rocket with its Mars Exploration Rover (MER-A) payload as it hurtles into space. Liftoff occurred on time at 1:58 p.m. EDT from Launch Complex 17-A, Cape Canaveral Air Force Station. MER-A, known as "Spirit," is the first of two rovers being launched to Mars. When the two rovers arrive at the red planet in 2004, they will bounce to airbag-cushioned landings at sites offering a balance of favorable conditions for safe landings and interesting science. The rovers see sharper images, can explore farther and examine rocks better than anything that has ever landed on Mars. The designated site for the MER-A mission is Gusev Crater, which appears to have been a crater lake. The second rover, MER-B, is scheduled to launch June 25.

  9. SHARC II Observations of the Galactic Center

    NASA Astrophysics Data System (ADS)

    Staguhn, J. G.; Benford, D. J.; Dowell, C. D.

    2003-05-01

    We present the first images of the Galactic Center region obtained with the new Caltech Submillimeter Observatory facility camera SHARC II. Most of the observations show the 350μ m dust continuum emission from this region. The observing mode we used is similar to fast scanning. This mode does not require on- and off-source observations, since the emission from the sky and detector noise can be derived from the on source observations alone. This is possible because the fast scanning on the sky provides spatial correlations between bolometer pixels due to atmospheric emission and temporal correlations between pixels due to celestial emission. This difference of correlations permits the separation of the atmosphere from the celestial source. The observations therefore do not suffer from possible contamination from emission in an off position used for sky subtraction.

  10. ALIDA-II: An Improved Disclosure Scale.

    PubMed

    van Dam, Mary Ann

    2015-01-01

    Disclosure, or degree of "outness" has been recognized as an important measurement in lesbian and gay populations to provide better understanding of various health issues associated with disclosure. In 2008, A Lesbian Identity Disclosure Assessment (ALIDA) was created to quantify the daily degree of disclosure. Reliability for the instrument was adequate for both lesbians with and without children. It was recognized, through statistical analysis, that the instrument may be lacking an important concept that, when included, may raise the instrument's reliability. Hence, the concept of "general public" disclosure was added to ALIDA-II, and the instrument was tested in a new study. Reliability for lesbians with and without children increased to ideal levels with consistent factor analyses and predictive variables on regression models. This instrument should be used widely, and although the instrument has been used in lesbians only, the use in gay men is now being tested.

  11. Women in Astronomy II: Ten Years After

    NASA Technical Reports Server (NTRS)

    Sargent, Wallace

    2004-01-01

    The meeting "Women in Astronomy II: Ten Years After" took place at the California Institute of Technology in Pasadena, CA June 27-28, 2003. The meeting was sponsored by the Committee on the Status of Women of the American Astronomical Society and was attended by about 155 participants. The purpose of the meeting was: "To review the current status of women in astronomy, understand their work environment, assess development since the 1992 Baltimore conference, and recommend future actions that will improve the environment for all astronomers." A description of the meeting and its background can be found at http://www.aas.org/%7Ecswa/WIA2003.html. The proceedings are being edited by Profs. Meg Urry (Yale University) and Ran Bagenal (University of Colorado). The principal outcome of WIAII was a series of recommendations, "The Pasadena Recommendations", which have been approved by the AAS Council and which can be found at http://www.aas.org/%7Ecswa/.

  12. Nucleosynthesis in Type II Supernova Explosions

    NASA Astrophysics Data System (ADS)

    Elliott, Carrie; Hix, W. Raphael; Harris, A.; Manneschmidt, A.

    2016-09-01

    Type II are the most common class of the ``core collapse'' supernova, involving the destruction of a high mass star (> 8M⊙). Their death is a result of a self-gravitational force becoming unbalanced as fusion ceases in the stellar core, leading to the collapse of the core to form a neutron star. The propagation of the shock ignites fusion into heavier elements as it progress through the star. This process is the origin of most elements present in the universe. In recent years, the complex nature of the explosion (its hydrodynamics, transport of energy, and the created isotopes) have been studied with increasing physical fidelity. Detailed nucleosynthesis from models of these core collapse supernovae is calculated in a post-processing step, using thermodynamic trajectories. My work on the project has been to develop the tools to visualize the results of post-processing calculations in the 2D grid. National Science Foundation (NSF).

  13. Lunar Orbiter II - Photographic Mission Summary

    NASA Technical Reports Server (NTRS)

    1967-01-01

    Lunar Orbiter II photography of landing sites, and spacecraft systems performance. The second of five Lunar Orbiter spacecraft was successfully launched from Launch Complex 13 at the Air Force Eastern Test Range by an Atlas-Agena launch vehicle at 23:21 GMT on November 6, 1966. Tracking data from the Cape Kennedy and Grand Bahama tracking stations were used to control and guide the launch vehicle during Atlas powered flight. The Agena spacecraft combination was maneuvered into a 100-nautical-mile-altitude Earth orbit by the preset on-board Agena computer. In addition, the Agena computer determined the maneuver 1 and engine-bum period required to inject the spacecraft on the cislunar trajectory 20 minutes after launch. Tracking data from the downrange stations and the Johannesburg, South Africa station were used to monitor the entire boost trajectory.

  14. Promoting weight loss in type II diabetes.

    PubMed

    Brown, S A; Upchurch, S; Anding, R; Winter, M; Ramìrez, G

    1996-06-01

    To examine strategies-behavioral therapies, exercise, diet, anorectic drugs, surgery, or a combination of strategies-used for promoting weight loss in people with type II diabetes. Meta-analysis was used to synthesize research of promoting weight loss in the population. Literature search strategies involved reviewing bibliographies, conducting computer searches and surveys of relevant master's degree programs, and contacting representatives of the Centers for Disease Control. The final sample consisted of 89 studies involving 1,800 subjects. Data were extracted on 80 variables characterizing the sample of studies/subjects and on 23 outcome variables, including weight, metabolic control, lipids, and other physiological parameters. Diet alone had the largest statistically significant impact on weight loss (-20 lb) and metabolic control (-2.7% in glycosylated hemoglobin). All diets significantly improved fasting blood sugar. Behavioral programs alone had a statistically significant impact on weight loss (-6.4 lb) and metabolic control (-1.5%) but effects were less than for diet alone. Data from the few exercise studies indicated that weighted average effects for exercise on weight loss (-3.4 lb) and metabolic control (-0.8%) were less than diet alone. Behavioral therapy plus diet plus exercise was associated with statistically significant effect size estimates for weight loss (-8.5 lb) and metabolic control (-1.6%). Diet alone achieved better results. Effects of weight promotion strategies, in general, were smaller in experimental studies and for individuals over age 55. Dietary strategies are most effective for promoting short-term weight loss in type II diabetes. A number of gaps exist in the extant literature- descriptions of subjects, interventions, or longitudinal outcomes beyond 12 months after intervention.

  15. Wavelengths, energy levels and hyperfine structure of Mn II and Sc II.

    NASA Astrophysics Data System (ADS)

    Nave, Gillian; Pickering, Juliet C.; Townley-Smith, Keeley I. M.; Hala, .

    2015-08-01

    For many decades, the Atomic Spectroscopy Groups at the National Institute of Standards and Technology (NIST) and Imperial College London (ICL) have measured atomic data of astronomical interest. Our spectrometers include Fourier transform (FT) spectrometers at NIST and ICL covering the region 1350 Å to 5.5 μm and a 10.7-m grating spectrometer at NIST covering wavelengths from 300 - 5000 Å. Sources for these spectra include high-current continuous and pulsed hollow cathode (HCL) lamps, Penning discharges, and sliding spark discharges. Recent work has focused on the measurement and analysis of wavelengths, energy levels, and hyperfine structure (HFS) constants for iron-group elements. The analysis of FT spectra of Cr I, Mn I, and Mn II is being led by ICL and is described in a companion poster [1]. Current work being led by NIST includes the analysis of HFS in Mn II, analysis of Mn II in the vacuum ultraviolet, and a comprehensive analysis of Sc II.Comprehensive HFS constants for Mn II are needed for the interpretation of stellar spectra and incorrect abundances may be obtained when HFS is omitted. Holt et al. [2] have measured HFS constants for 59 levels of Mn II using laser spectroscopy. We used FT spectra of Mn/Ni and Mn/Cu HCLs covering wavelength ranges from 1350 Å to 5.4 μm to confirm 26 of the A constants of Holt et al. and obtain values for roughly 40 additional levels. We aim to obtain HFS constants for the majority of lines showing significant HFS that are observed in chemically-peculiar stars.Spectra of Sc HCLs have been recorded from 1800 - 6700 Å using a vacuum ultraviolet FT spectrometer at NIST. Additional measurements to cover wavelengths above 6700 Å and below 1800 Å are in progress. The spectra are being analyzed by NIST and Alighar Muslim University, India in order to derive improved wavelengths, energy levels, and hyperfine structure parameters.This work was partially supported by NASA, the STFC and PPARC (UK), the Royal Society of the UK

  16. The Portuguese long version of the Copenhagen Psychosocial Questionnaire II (COPSOQ II) - a validation study.

    PubMed

    Rosário, Susel; Azevedo, Luís F; Fonseca, João A; Nienhaus, Albert; Nübling, Matthias; da Costa, José Torres

    2017-01-01

    Psychosocial risks are now widely recognised as one of the biggest challenges for occupational safety and health (OSH) and a major public health concern. The aim of this paper is to investigate the Portuguese long version of the Copenhagen Psychosocial Questionnaire II (COPSOQ II), in order to analyse the psychometric properties of the instrument and to validate it. The Portuguese COPSOQ II was issued to a total of 745 Portuguese employees from both private and public organisations across several economic sectors at a baseline and then 2 weeks later. Methodological quality appraisal was based on COnsensus-based Standards for the selection of health Measurement INstruments (COSMIN) recommendations. An analysis of the psychometric properties of the long version of COPSOQ II (internal consistency, intraclass correlation coefficient, floor and ceiling effects, response rate, missing values, mean and standard deviation, exploratory factor analysis) was performed to determine the validity and reliability of the instrument. The COPSOQ II had a response rate of 60.6% (test) and a follow-up response rate of 59.5% (retest). In general, a Cronbach's alpha of the COPSOQ scales (test and retest) was above the conventional threshold of 0.70. The test-retest reliability estimated by the intraclass correlation coefficient (ICC) showed a higher reliability for most of the scales, above the conventional 0.7, except for eight scales. The proportion of the missing values was less than 1.3%, except for two scales. The average scores and standard deviations showed similar results to the original Danish study, except for eight scales. All of the scales had low floor and ceiling effects, with one exception . Overall, the exploratory factor analysis presented good results in 27 scales assuming a reflective measurement model. The hypothesized factor structure under a reflective model was not supported in 14 scales and for some but not all of these scales the explanation may be a formative

  17. Tuning the reactivity of osmium(II) and ruthenium(II) arene complexes under physiological conditions.

    PubMed

    Peacock, Anna F A; Habtemariam, Abraha; Fernández, Rafael; Walland, Victoria; Fabbiani, Francesca P A; Parsons, Simon; Aird, Rhona E; Jodrell, Duncan I; Sadler, Peter J

    2006-02-08

    The Os(II) arene ethylenediamine (en) complexes [(eta(6)-biphenyl)Os(en)Cl][Z], Z = BPh(4) (4) and BF(4) (5), are inactive toward A2780 ovarian cancer cells despite 4 being isostructural with an active Ru(II) analogue, 4R. Hydrolysis of 5 occurred 40 times more slowly than 4R. The aqua adduct 5A has a low pK(a) (6.3) compared to that of [(eta(6)-biphenyl)Ru(en)(OH(2))](2+) (7.7) and is therefore largely in the hydroxo form at physiological pH. The rate and extent of reaction of 5 with 9-ethylguanine were also less than those of 4R. We replaced the neutral en ligand by anionic acetylacetonate (acac). The complexes [(eta(6)-arene)Os(acac)Cl], arene = biphenyl (6), benzene (7), and p-cymene (8), adopt piano-stool structures similar to those of the Ru(II) analogues and form weak dimers through intermolecular (arene)C-H...O(acac) H-bonds. Remarkably, these Os(II) acac complexes undergo rapid hydrolysis to produce not only the aqua adduct, [(eta(6)-arene)Os(acac)(OH(2))](+), but also the hydroxo-bridged dimer, [(eta(6)-arene)Os(mu(2)-OH)(3)Os(eta(6)-arene)](+). The pK(a) values for the aqua adducts 6A, 7A, and 8A (7.1, 7.3, and 7.6, respectively) are lower than that for [(eta(6)-p-cymene)Ru(acac)(OH(2))](+) (9.4). Complex 8A rapidly forms adducts with 9-ethylguanine and adenosine, but not with cytidine or thymidine. Despite their reactivity toward nucleobases, complexes 6-8 were inactive toward A549 lung cancer cells. This is attributable to rapid hydrolysis and formation of unreactive hydroxo-bridged dimers which, surprisingly, were the only species present in aqueous solution at biologically relevant concentrations. Hence, the choice of chelating ligand in Os(II) (and Ru(II)) arene complexes can have a dramatic effect on hydrolysis behavior and nucleobase binding and provides a means of tuning the reactivity and the potential for discovery of anticancer complexes.

  18. Glutamate Ligation in the Ni(II)- and Co(II)-Responsive Escherichia coli Transcriptional Regulator, RcnR

    SciTech Connect

    Carr, Carolyn E.; Musiani, Francesco; Huang, Hsin-Ting

    2017-05-18

    Escherichia coli RcnR (resistance to cobalt and nickel regulator, EcRcnR) is a metal-responsive repressor of the genes encoding the Ni(II) and Co(II) exporter proteins RcnAB by binding to PRcnAB. The DNA binding affinity is weakened when the cognate ions Ni(II) and Co(II) bind to EcRcnR in a six-coordinate site that features a (N/O)5S ligand donor-atom set in distinct sites: while both metal ions are bound by the N terminus, Cys35, and His64, Co(II) is additionally bound by His3. On the other hand, the noncognate Zn(II) and Cu(I) ions feature a lower coordination number, have a solvent-accessible binding site, and coordinatemore » protein ligands that do not include the N-terminal amine. A molecular model of apo-EcRcnR suggested potential roles for Glu34 and Glu63 in binding Ni(II) and Co(II) to EcRcnR. The roles of Glu34 and Glu63 in metal binding, metal selectivity, and function were therefore investigated using a structure/function approach. X-ray absorption spectroscopy was used to assess the structural changes in the Ni(II), Co(II), and Zn(II) binding sites of Glu → Ala and Glu → Cys variants at both positions. The effect of these structural alterations on the regulation of PrcnA by EcRcnR in response to metal binding was explored using LacZ reporter assays. These combined studies indicate that while Glu63 is a ligand for both metal ions, Glu34 is a ligand for Co(II) but possibly not for Ni(II). The Glu34 variants affect the structure of the cognate metal sites, but they have no effect on the transcriptional response. In contrast, the Glu63 variants affect both the structure and transcriptional response, although they do not completely abolish the function of EcRcnR. The structure of the Zn(II) site is not significantly perturbed by any of the glutamic acid variations. The spectroscopic and functional data obtained on the mutants were used to calculate models of the metal-site structures of EcRcnR bound to Ni(II), Co(II), and Zn(II). The results are

  19. NDCX-II project commencing at LBNL

    SciTech Connect

    Friedman, A; Kwan, J

    2009-10-22

    Earlier this year, the U.S. Department of Energy Office of Fusion Energy Sciences approved the NDCX-II project, a second-generation Neutralized Drift Compression eXperiment. NDCX-II is a collaborative effort of scientists and engineers from Lawrence Berkeley National Laboratory (LBNL), Lawrence Livermore National Laboratory (LLNL), and the Princeton Plasma Physics Laboratory (PPPL), in a formal collaboration known as the Virtual National Laboratory for Heavy Ion Fusion Science (HIFS-VNL). Supported by $11 M of funding from the American Recovery and Reinvestment Act, construction at LBNL commenced in July of 2009, with completion anticipated in March of 2012. Applications of this facility will includemore » studies of: the basic physics of the poorly understood 'warm dense matter' regime of temperatures around 1 eV and densities near solid, using uniform, volumetric ion heating of thin foil targets; ion energy coupling into an ablating plasma (such as that which occurs in an inertial fusion target) using beams with time-varying kinetic energy; space-charge-dominated ion beam dynamics; and beam focusing and pulse compression in neutralizing plasma. The machine will complement facilities at GSI in Darmstadt, Germany, but will employ lower ion kinetic energies and commensurately shorter stopping ranges in matter. Much of this research will contribute directly toward the collaboration's ultimate goal of electric power production via heavy-ion beam-driven inertial confinement fusion ('Heavy-Ion Fusion', or HIF). In inertial fusion, a target containing fusion fuel is heated by energetic 'driver' beams, and undergoes a miniature thermonuclear explosion. Currently the largest U.S. research program in inertial confinement is at Livermore's National Ignition Facility (NIF), a multibillion-dollar, stadium-sized laser facility optimized for studying physics issues relevant to nuclear stockpile stewardship. Nonetheless, NIF is expected to establish the fundamental feasibility

  20. Csk regulates angiotensin II-induced podocyte apoptosis.

    PubMed

    Zhang, Lu; Ren, Zhilong; Yang, Qian; Ding, Guohua

    2016-07-01

    Increasing data have shown that angiotensin II (Ang II) perpetuates podocyte injury and promotes progression to end-stage kidney disease. The mechanism underlying Ang II-induced podocyte apoptosis has not been established. C-terminal Src kinase (Csk) is a cytoplasmic kinase that interacts with scaffolding proteins involved in cell growth, adhesion, and polarization, and the role of Csk in regulating cellular apoptosis has gradually attracted attention. This study evaluates the role of Csk in Ang II-induced podocyte apoptosis. In vivo, Wistar rats were randomly subjected to a normal saline or Ang II infusion. In vitro, we exposed differentiated mouse podocytes to Ang II. Ang II increased Csk expression and induced podocyte apoptosis, stimulated Csk translocation and binding to Caveolin-1, and stimulated decreased Fyn pY416, increased Fyn pY529, and nephrin dephosphorylation. Csk knockdown prevented Ang II-induced podocyte apoptosis, reduced Fyn kinase inactivation, and increased the interaction between nephrin and the activated form of Fyn, accompanied by a reduced interaction between Csk and Caveolin-1. These findings indicate that Ang II induces podocyte injury via a Csk-dependent pathway.