Sample records for classification guide nuclear

  1. 10 CFR 1045.37 - Classification guides.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 4 2014-01-01 2014-01-01 false Classification guides. 1045.37 Section 1045.37 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) NUCLEAR CLASSIFICATION AND DECLASSIFICATION Generation and Review of Documents Containing Restricted Data and Formerly Restricted Data § 1045.37 Classification guides...

  2. 10 CFR 1045.37 - Classification guides.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 4 2013-01-01 2013-01-01 false Classification guides. 1045.37 Section 1045.37 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) NUCLEAR CLASSIFICATION AND DECLASSIFICATION Generation and Review of Documents Containing Restricted Data and Formerly Restricted Data § 1045.37 Classification guides...

  3. 10 CFR 1045.37 - Classification guides.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 4 2012-01-01 2012-01-01 false Classification guides. 1045.37 Section 1045.37 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) NUCLEAR CLASSIFICATION AND DECLASSIFICATION Generation and Review of Documents Containing Restricted Data and Formerly Restricted Data § 1045.37 Classification guides...

  4. 10 CFR 1045.37 - Classification guides.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Classification guides. 1045.37 Section 1045.37 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) NUCLEAR CLASSIFICATION AND DECLASSIFICATION Generation and Review of Documents Containing Restricted Data and Formerly Restricted Data § 1045.37 Classification guides...

  5. 10 CFR 1045.37 - Classification guides.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 4 2011-01-01 2011-01-01 false Classification guides. 1045.37 Section 1045.37 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) NUCLEAR CLASSIFICATION AND DECLASSIFICATION Generation and Review of Documents Containing Restricted Data and Formerly Restricted Data § 1045.37 Classification guides...

  6. 14 CFR 1203.412 - Classification guides.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 5 2013-01-01 2013-01-01 false Classification guides. 1203.412 Section... PROGRAM Guides for Original Classification § 1203.412 Classification guides. (a) General. A classification guide, based upon classification determinations made by appropriate program and classification...

  7. 14 CFR 1203.412 - Classification guides.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 5 2012-01-01 2012-01-01 false Classification guides. 1203.412 Section... PROGRAM Guides for Original Classification § 1203.412 Classification guides. (a) General. A classification guide, based upon classification determinations made by appropriate program and classification...

  8. 14 CFR 1203.412 - Classification guides.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 5 2011-01-01 2010-01-01 true Classification guides. 1203.412 Section 1203... Guides for Original Classification § 1203.412 Classification guides. (a) General. A classification guide, based upon classification determinations made by appropriate program and classification authorities...

  9. 14 CFR § 1203.412 - Classification guides.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 5 2014-01-01 2014-01-01 false Classification guides. § 1203.412 Section... PROGRAM Guides for Original Classification § 1203.412 Classification guides. (a) General. A classification guide, based upon classification determinations made by appropriate program and classification...

  10. 32 CFR 2001.15 - Classification guides.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 6 2013-07-01 2013-07-01 false Classification guides. 2001.15 Section 2001.15..., NATIONAL ARCHIVES AND RECORDS ADMINISTRATION CLASSIFIED NATIONAL SECURITY INFORMATION Classification § 2001.15 Classification guides. (a) Preparation of classification guides. Originators of classification...

  11. 32 CFR 2001.15 - Classification guides.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 6 2012-07-01 2012-07-01 false Classification guides. 2001.15 Section 2001.15..., NATIONAL ARCHIVES AND RECORDS ADMINISTRATION CLASSIFIED NATIONAL SECURITY INFORMATION Classification § 2001.15 Classification guides. (a) Preparation of classification guides. Originators of classification...

  12. 32 CFR 2001.15 - Classification guides.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 6 2014-07-01 2014-07-01 false Classification guides. 2001.15 Section 2001.15..., NATIONAL ARCHIVES AND RECORDS ADMINISTRATION CLASSIFIED NATIONAL SECURITY INFORMATION Classification § 2001.15 Classification guides. (a) Preparation of classification guides. Originators of classification...

  13. 32 CFR 2001.15 - Classification guides.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 6 2010-07-01 2010-07-01 false Classification guides. 2001.15 Section 2001.15..., NATIONAL ARCHIVES AND RECORDS ADMINISTRATION CLASSIFIED NATIONAL SECURITY INFORMATION Classification § 2001.15 Classification guides. (a) Preparation of classification guides. Originators of classification...

  14. 32 CFR 2001.15 - Classification guides.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 6 2011-07-01 2011-07-01 false Classification guides. 2001.15 Section 2001.15..., NATIONAL ARCHIVES AND RECORDS ADMINISTRATION CLASSIFIED NATIONAL SECURITY INFORMATION Classification § 2001.15 Classification guides. (a) Preparation of classification guides. Originators of classification...

  15. 32 CFR 2700.22 - Classification guides.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 6 2012-07-01 2012-07-01 false Classification guides. 2700.22 Section 2700.22... SECURITY INFORMATION REGULATIONS Derivative Classification § 2700.22 Classification guides. OMSN shall issue classification guides pursuant to section 2-2 of E.O. 12065. These guides, which shall be used to...

  16. 32 CFR 2700.22 - Classification guides.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 6 2014-07-01 2014-07-01 false Classification guides. 2700.22 Section 2700.22... SECURITY INFORMATION REGULATIONS Derivative Classification § 2700.22 Classification guides. OMSN shall issue classification guides pursuant to section 2-2 of E.O. 12065. These guides, which shall be used to...

  17. 32 CFR 2700.22 - Classification guides.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 6 2013-07-01 2013-07-01 false Classification guides. 2700.22 Section 2700.22... SECURITY INFORMATION REGULATIONS Derivative Classification § 2700.22 Classification guides. OMSN shall issue classification guides pursuant to section 2-2 of E.O. 12065. These guides, which shall be used to...

  18. 32 CFR 2700.22 - Classification guides.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 6 2011-07-01 2011-07-01 false Classification guides. 2700.22 Section 2700.22... SECURITY INFORMATION REGULATIONS Derivative Classification § 2700.22 Classification guides. OMSN shall issue classification guides pursuant to section 2-2 of E.O. 12065. These guides, which shall be used to...

  19. Combinational pixel-by-pixel and object-level classifying, segmenting, and agglomerating in performing quantitative image analysis that distinguishes between healthy non-cancerous and cancerous cell nuclei and delineates nuclear, cytoplasm, and stromal material objects from stained biological tissue materials

    DOEpatents

    Boucheron, Laura E

    2013-07-16

    Quantitative object and spatial arrangement-level analysis of tissue are detailed using expert (pathologist) input to guide the classification process. A two-step method is disclosed for imaging tissue, by classifying one or more biological materials, e.g. nuclei, cytoplasm, and stroma, in the tissue into one or more identified classes on a pixel-by-pixel basis, and segmenting the identified classes to agglomerate one or more sets of identified pixels into segmented regions. Typically, the one or more biological materials comprises nuclear material, cytoplasm material, and stromal material. The method further allows a user to markup the image subsequent to the classification to re-classify said materials. The markup is performed via a graphic user interface to edit designated regions in the image.

  20. 32 CFR 2700.22 - Classification guides.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... SECURITY INFORMATION REGULATIONS Derivative Classification § 2700.22 Classification guides. OMSN shall... direct derivative classification, shall identify the information to be protected in specific and uniform...

  1. Comprehensive phylogeny, biogeography and new classification of the diverse bee tribe Megachilini: Can we use DNA barcodes in phylogenies of large genera?

    PubMed

    Trunz, V; Packer, L; Vieu, J; Arrigo, N; Praz, C J

    2016-10-01

    Classification and evolutionary studies of particularly speciose clades pose important challenges, as phylogenetic analyses typically sample a small proportion of the existing diversity. We examine here one of the largest bee genera, the genus Megachile - the dauber and leafcutting bees. Besides presenting a phylogeny based on five nuclear genes (5480 aligned nucleotide positions), we attempt to use the phylogenetic signal of mitochondrial DNA barcodes, which are rapidly accumulating and already include a substantial proportion of the known species diversity in the genus. We used barcodes in two ways: first, to identify particularly divergent lineages and thus to guide taxon sampling in our nuclear phylogeny; second, to augment taxon sampling by combining nuclear markers (as backbone for ancient divergences) with DNA barcodes. Our results indicate that DNA barcodes bear phylogenetic signal limited to very recent divergences (3-4 my before present). Sampling within clades of very closely related species may be augmented using this technique, but our results also suggest statistically supported, but incongruent placements of some taxa. However, the addition of one single nuclear gene (LW-rhodopsin) to the DNA barcode data was enough to recover meaningful placement with high clade support values for nodes up to 15 million years old. We discuss different proposals for the generic classification of the tribe Megachilini. Finding a classification that is both in agreement with our phylogenetic hypotheses and practical in terms of diagnosability is particularly challenging as our analyses recover several well-supported clades that include morphologically heterogeneous lineages. We favour a classification that recognizes seven morphologically well-delimited genera in Megachilini: Coelioxys, Gronoceras, Heriadopsis, Matangapis, Megachile, Noteriades and Radoszkowskiana. Our results also lead to the following classification changes: the groups known as Dinavis, Neglectella, Eurymella and Phaenosarus are reestablished as valid subgenera of the genus Megachile, while the subgenus Alocanthedon is placed in synonymy with M. (Callomegachile), the subgenera Parachalicodoma and Largella with M. (Pseudomegachile), Anodonteutricharaea with M. (Paracella), Platysta with M. (Eurymella), and Grosapis and Eumegachile with M. (Megachile) (new synonymies). In addition, we use maximum likelihood reconstructions of ancestral geographic ranges to infer the origin of the tribe and reconstruct the main dispersal routes explaining the current, cosmopolitan distribution of this genus. Copyright © 2016 Elsevier Inc. All rights reserved.

  2. Taxonomy for Common-Cause Failure Vulnerability and Mitigation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wood, Richard Thomas; Korsah, Kofi; Mullens, James Allen

    2015-09-01

    Applying current guidance and practices for common-cause failure (CCF) mitigation to digital instrumentation and control (I&C) systems has proven problematic, and the regulatory environment has been unpredictable. The potential for CCF vulnerability inhibits I&C modernization, thereby challenging the long-term sustainability of existing plants. For new plants and advanced reactor concepts, concern about CCF vulnerability in highly integrated digital I&C systems imposes a design burden that results in higher costs and increased complexity. The regulatory uncertainty in determining which mitigation strategies will be acceptable (e.g., what diversity is needed and how much is sufficient) drives designers to adopt complicated, costly solutionsmore » devised for existing plants. To address the conditions that constrain the transition to digital I&C technology by the US nuclear industry, crosscutting research is needed to resolve uncertainty, demonstrate necessary characteristics, and establish an objective basis for qualification of digital technology for nuclear power plant (NPP) I&C applications. To fulfill this research need, Oak Ridge National Laboratory is investigating mitigation of CCF vulnerability for nuclear-qualified applications. The outcome of this research is expected to contribute to a fundamentally sound, comprehensive basis to qualify digital technology for nuclear power applications. This report documents the development of a CCF taxonomy. The basis for the CCF taxonomy was generated by determining consistent terminology and establishing a classification approach. The terminology is based on definitions from standards, guides, and relevant nuclear power industry technical reports. The classification approach is derived from identified classification schemes focused on I&C systems and key characteristics, including failure modes. The CCF taxonomy provides the basis for a systematic organization of key systems aspects relevant to analyzing the potential for CCF vulnerability and the suitability of mitigation techniques. Development of an effective CCF taxonomy will help to provide a framework for establishing the objective analysis and assessment capabilities desired to facilitate rigorous identification of fault types and triggers that are the fundamental elements of CCF.« less

  3. 77 FR 8902 - Draft Regulatory Guide: Issuance, Availability Decommissioning of Nuclear Power Reactors

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-15

    ... Decommissioning of Nuclear Power Reactors AGENCY: Nuclear Regulatory Commission. ACTION: Draft regulatory guide... draft regulatory guide (DG) DG-1271 ``Decommissioning of Nuclear Power Reactors.'' This guide describes... Regulatory Guide 1.184, ``Decommissioning of Nuclear Power Reactors,'' dated July 2000. This proposed...

  4. NASA Scope and Subject Category Guide

    NASA Technical Reports Server (NTRS)

    2011-01-01

    This guide provides a simple, effective tool to assist aerospace information analysts and database builders in the high-level subject classification of technical materials. Each of the 76 subject categories comprising the classification scheme is presented with a description of category scope, a listing of subtopics, cross references, and an indication of particular areas of NASA interest. The guide also includes an index of nearly 3,000 specific research topics cross referenced to the subject categories. The portable document format (PDF) version of the guide contains links in the index from each input subject to its corresponding categories. In addition to subject classification, the guide can serve as an aid to searching databases that use the classification scheme, and is also an excellent selection guide for those involved in the acquisition of aerospace literature. The CD-ROM contains both HTML and PDF versions.

  5. Cataloging Guide for Instructional Materials Used in Livonia Public Schools Instructional Materials Centers.

    ERIC Educational Resources Information Center

    Livonia Public Schools, MI.

    This working guide for Livonia's Public Schools provides detailed instructions in preparing and handling catalog cards, a supplemental cataloging and classification guide, and typing rules for technical processing. Standard abbreviations are given for making classification entries, and separate cataloging instructions are given for charts,…

  6. Rule-guided human classification of Volunteered Geographic Information

    NASA Astrophysics Data System (ADS)

    Ali, Ahmed Loai; Falomir, Zoe; Schmid, Falko; Freksa, Christian

    2017-05-01

    During the last decade, web technologies and location sensing devices have evolved generating a form of crowdsourcing known as Volunteered Geographic Information (VGI). VGI acted as a platform of spatial data collection, in particular, when a group of public participants are involved in collaborative mapping activities: they work together to collect, share, and use information about geographic features. VGI exploits participants' local knowledge to produce rich data sources. However, the resulting data inherits problematic data classification. In VGI projects, the challenges of data classification are due to the following: (i) data is likely prone to subjective classification, (ii) remote contributions and flexible contribution mechanisms in most projects, and (iii) the uncertainty of spatial data and non-strict definitions of geographic features. These factors lead to various forms of problematic classification: inconsistent, incomplete, and imprecise data classification. This research addresses classification appropriateness. Whether the classification of an entity is appropriate or inappropriate is related to quantitative and/or qualitative observations. Small differences between observations may be not recognizable particularly for non-expert participants. Hence, in this paper, the problem is tackled by developing a rule-guided classification approach. This approach exploits data mining techniques of Association Classification (AC) to extract descriptive (qualitative) rules of specific geographic features. The rules are extracted based on the investigation of qualitative topological relations between target features and their context. Afterwards, the extracted rules are used to develop a recommendation system able to guide participants to the most appropriate classification. The approach proposes two scenarios to guide participants towards enhancing the quality of data classification. An empirical study is conducted to investigate the classification of grass-related features like forest, garden, park, and meadow. The findings of this study indicate the feasibility of the proposed approach.

  7. 76 FR 46330 - NUREG-1934, Nuclear Power Plant Fire Modeling Application Guide (NPP FIRE MAG); Second Draft...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-02

    ... NUCLEAR REGULATORY COMMISSION [NRC-2009-0568] NUREG-1934, Nuclear Power Plant Fire Modeling Application Guide (NPP FIRE MAG); Second Draft Report for Comment AGENCY: Nuclear Regulatory Commission... 1023259), ``Nuclear Power Plant Fire Modeling Application Guide (NPP FIRE MAG), Second Draft Report for...

  8. 78 FR 53774 - Guide for the Evaluation of Alert and Notification Systems for Nuclear Power Plants, FEMA-REP-10...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-30

    ...] Guide for the Evaluation of Alert and Notification Systems for Nuclear Power Plants, FEMA-REP-10, Rev. 1... the Guide for the Evaluation of Alert and Notification Systems for Nuclear Power Plants, FEMA-REP-10... Agency (FEMA) issued FEMA-REP-10, Guide for the Evaluation of Alert and Notification Systems for Nuclear...

  9. High-Altitude Electromagnetic Pulse (HEMP) Testing

    DTIC Science & Technology

    2011-11-10

    Security Classification Guide ( SCG ). b. The HEMP simulation facility shall have a measured map of the peak amplitude waveform of the...Quadripartite Standardization Agreement s, sec second SCG security classification guide SN serial number SOP Standard Operating Procedure

  10. Acceptable Risk? The Nuclear Age in the United States. Study/Action Guide [and] Companion to Study/Action Guide for Congregations and Religious Groups.

    ERIC Educational Resources Information Center

    American Friends Service Committee, Philadelphia, PA. National Action/Research on the Military Industrial Complex.

    A study-action guide and a companion guide are intended to help citizens explore some of the challenging dilemmas of U.S. nuclear policy. The two guides place strong emphasis on group discussion and participation as well as action citizens might want to take to bring about a non-nuclear world. The companion guide is intended for congregations and…

  11. Guide to the TANDEM System for the Modern Languages Department Tape Library: A Non-Technical Guide for Teachers.

    ERIC Educational Resources Information Center

    Hounsell, D.; And Others

    This guide for teachers to the tape indexing system (TANDEM) in use at the Modern Languages Department at Portsmouth Polytechnic focuses on tape classification, numbering, labeling, and shelving system procedures. The appendixes contain information on: (1) the classification system and related codes, (2) color and letter codes, (3) marking of tape…

  12. Analysis and classification of the tools for assessing the risks associated with industrial machines.

    PubMed

    Paques, Joseph-Jean; Gauthier, François; Perez, Alejandro

    2007-01-01

    To assess and plan future risk-analysis research projects, 275 documents describing methods and tools for assessing the risks associated with industrial machines or with other sectors such as the military, and the nuclear and aeronautics industries, etc., were collected. These documents were in the format of published books or papers, standards, technical guides and company procedures collected throughout industry. From the collected documents, 112 documents were selected for analysis; 108 methods applied or potentially applicable for assessing the risks associated with industrial machines were analyzed and classified. This paper presents the main quantitative results of the analysis of the methods and tools.

  13. Nuclear Technology Series. Nuclear Reactor (Plant) Operator Trainee. A Suggested Program Planning Guide. Revised June 80.

    ERIC Educational Resources Information Center

    Center for Occupational Research and Development, Inc., Waco, TX.

    This program planning guide for a two-year postsecondary nuclear reactor (plant) operator trainee program is designed for use with courses 1-16 of thirty-five in the Nuclear Technology Series. The purpose of the guide is to describe the nuclear power field and its job categories for specialists, technicians and operators; and to assist planners,…

  14. 75 FR 1830 - Final Regulatory Guide: Issuance, Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-13

    ... review of applications for permits and licenses. RG 5.71, ``Cyber Security Programs for Nuclear... NUCLEAR REGULATORY COMMISSION [NRC-2010-0009] Final Regulatory Guide: Issuance, Availability AGENCY: Nuclear Regulatory Commission. ACTION: Notice of Issuance and Availability of Regulatory Guide...

  15. 78 FR 38739 - Special Nuclear Material Control and Accounting Systems for Nuclear Power Plants

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-27

    ... NUCLEAR REGULATORY COMMISSION [NRC-2012-0109] Special Nuclear Material Control and Accounting... Guide (RG) 5.29, ``Special Nuclear Material Control and Accounting Systems for Nuclear Power Plants... material control and accounting. This guide applies to all nuclear power plants. ADDRESSES: Please refer to...

  16. 14 CFR 1203.406 - Additional classification factors.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... PROGRAM Guides for Original Classification § 1203.406 Additional classification factors. In determining the appropriate classification category, the following additional factors should be considered: (a... 14 Aeronautics and Space 5 2011-01-01 2010-01-01 true Additional classification factors. 1203.406...

  17. 32 CFR 2400.15 - Classification guides.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 6 2012-07-01 2012-07-01 false Classification guides. 2400.15 Section 2400.15 National Defense Other Regulations Relating to National Defense OFFICE OF SCIENCE AND TECHNOLOGY POLICY REGULATIONS TO IMPLEMENT E.O. 12356; OFFICE OF SCIENCE AND TECHNOLOGY POLICY INFORMATION SECURITY PROGRAM...

  18. 32 CFR 2400.15 - Classification guides.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 6 2010-07-01 2010-07-01 false Classification guides. 2400.15 Section 2400.15 National Defense Other Regulations Relating to National Defense OFFICE OF SCIENCE AND TECHNOLOGY POLICY REGULATIONS TO IMPLEMENT E.O. 12356; OFFICE OF SCIENCE AND TECHNOLOGY POLICY INFORMATION SECURITY PROGRAM...

  19. 32 CFR 2400.15 - Classification guides.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 6 2011-07-01 2011-07-01 false Classification guides. 2400.15 Section 2400.15 National Defense Other Regulations Relating to National Defense OFFICE OF SCIENCE AND TECHNOLOGY POLICY REGULATIONS TO IMPLEMENT E.O. 12356; OFFICE OF SCIENCE AND TECHNOLOGY POLICY INFORMATION SECURITY PROGRAM...

  20. 32 CFR 2400.15 - Classification guides.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 6 2014-07-01 2014-07-01 false Classification guides. 2400.15 Section 2400.15 National Defense Other Regulations Relating to National Defense OFFICE OF SCIENCE AND TECHNOLOGY POLICY REGULATIONS TO IMPLEMENT E.O. 12356; OFFICE OF SCIENCE AND TECHNOLOGY POLICY INFORMATION SECURITY PROGRAM...

  1. 32 CFR 2400.15 - Classification guides.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 6 2013-07-01 2013-07-01 false Classification guides. 2400.15 Section 2400.15 National Defense Other Regulations Relating to National Defense OFFICE OF SCIENCE AND TECHNOLOGY POLICY REGULATIONS TO IMPLEMENT E.O. 12356; OFFICE OF SCIENCE AND TECHNOLOGY POLICY INFORMATION SECURITY PROGRAM...

  2. 75 FR 18241 - Draft Regulatory Guide: Issuance, Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-09

    ... NUCLEAR REGULATORY COMMISSION [NRC-2010-0148] Draft Regulatory Guide: Issuance, Availability AGENCY: Nuclear Regulatory Commission. ACTION: Notice of Issuance and Availability of Draft Regulatory.... Introduction The U.S. Nuclear Regulatory Commission (NRC) is issuing for public comment a draft guide in the...

  3. 75 FR 45166 - Draft Regulatory Guide: Issuance, Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-02

    ... NUCLEAR REGULATORY COMMISSION [NRC-2010-0265] Draft Regulatory Guide: Issuance, Availability AGENCY: Nuclear Regulatory Commission. ACTION: Notice of Issuance and Availability of Draft Regulatory.... Introduction The U.S. Nuclear Regulatory Commission (NRC) is issuing for public comment a draft guide in the...

  4. 14 CFR § 1203.407 - Duration of classification.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 5 2014-01-01 2014-01-01 false Duration of classification. § 1203.407... SECURITY PROGRAM Guides for Original Classification § 1203.407 Duration of classification. (a) At the time of original classification, the original classification authority shall establish a specific date or...

  5. 75 FR 48382 - Draft Regulatory Guide: Issuance, Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-10

    ... NUCLEAR REGULATORY COMMISSION [NRC-2010-0275] Draft Regulatory Guide: Issuance, Availability AGENCY: Nuclear Regulatory Commission. ACTION: Notice of Issuance and Availability of Draft Regulatory Guide, DG-1228, ``Standard Format and Content of License Termination Plans for Nuclear Power Reactors.'' FOR FURTHER INFORMATION CONTACT: James C....

  6. 75 FR 20868 - Notice of Issuance of Regulatory Guide

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-21

    ...: Nuclear Regulatory Commission. ACTION: Notice of Issuance and Availability of Regulatory Guide 1.68.2... Water-Cooled Nuclear Power Plants.'' FOR FURTHER INFORMATION CONTACT: Mark P. Orr, Regulatory Guide... Shutdown Capability for Water-Cooled Nuclear Power Plants,'' was issued with a temporary identification as...

  7. Guide to the measurement of tree characteristics important to the quality classification for young hardwood trees

    Treesearch

    David L. Sonderman

    1979-01-01

    A procedure is shown for measuring external tree characteristics that are important in determining the current and future quality of young hardwood trees. This guide supplements a precious study which describes the quality classification system for young hardwood trees

  8. 15 CFR 2008.9 - Classification guides.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 15 Commerce and Foreign Trade 3 2010-01-01 2010-01-01 false Classification guides. 2008.9 Section 2008.9 Commerce and Foreign Trade Regulations Relating to Foreign Trade Agreements OFFICE OF THE UNITED STATES TRADE REPRESENTATIVE REGULATIONS TO IMPLEMENT E.O. 12065; OFFICE OF THE UNITED STATES TRADE...

  9. 15 CFR 2008.9 - Classification guides.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 15 Commerce and Foreign Trade 3 2012-01-01 2012-01-01 false Classification guides. 2008.9 Section 2008.9 Commerce and Foreign Trade Regulations Relating to Foreign Trade Agreements OFFICE OF THE UNITED STATES TRADE REPRESENTATIVE REGULATIONS TO IMPLEMENT E.O. 12065; OFFICE OF THE UNITED STATES TRADE...

  10. 15 CFR 2008.9 - Classification guides.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 15 Commerce and Foreign Trade 3 2011-01-01 2011-01-01 false Classification guides. 2008.9 Section 2008.9 Commerce and Foreign Trade Regulations Relating to Foreign Trade Agreements OFFICE OF THE UNITED STATES TRADE REPRESENTATIVE REGULATIONS TO IMPLEMENT E.O. 12065; OFFICE OF THE UNITED STATES TRADE...

  11. 15 CFR 2008.9 - Classification guides.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 15 Commerce and Foreign Trade 3 2013-01-01 2013-01-01 false Classification guides. 2008.9 Section 2008.9 Commerce and Foreign Trade Regulations Relating to Foreign Trade Agreements OFFICE OF THE UNITED STATES TRADE REPRESENTATIVE REGULATIONS TO IMPLEMENT E.O. 12065; OFFICE OF THE UNITED STATES TRADE...

  12. 15 CFR 2008.9 - Classification guides.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 15 Commerce and Foreign Trade 3 2014-01-01 2014-01-01 false Classification guides. 2008.9 Section 2008.9 Commerce and Foreign Trade Regulations Relating to Foreign Trade Agreements OFFICE OF THE UNITED STATES TRADE REPRESENTATIVE REGULATIONS TO IMPLEMENT E.O. 12065; OFFICE OF THE UNITED STATES TRADE...

  13. Seizure Recognition and Observation: A Guide for Allied Health Professionals.

    ERIC Educational Resources Information Center

    Epilepsy Foundation of America, Landover, MD.

    Intended for allied health professionals, this guide provides information on seizure recognition and classification to help them assist the patient, the family, and the treating physician in obtaining control of epileptic seizures. A section on seizure recognition describes epilepsy and seizures, covering seizure classification and the causes of…

  14. Suggestion on the safety classification of spent fuel dry storage in China’s pressurized water reactor nuclear power plant

    NASA Astrophysics Data System (ADS)

    Liu, Ting; Qu, Yunhuan; Meng, De; Zhang, Qiaoer; Lu, Xinhua

    2018-01-01

    China’s spent fuel storage in the pressurized water reactors(PWR) is stored with wet storage way. With the rapid development of nuclear power industry, China’s NPPs(NPPs) will not be able to meet the problem of the production of spent fuel. Currently the world’s major nuclear power countries use dry storage as a way of spent fuel storage, so in recent years, China study on additional spent fuel dry storage system mainly. Part of the PWR NPP is ready to apply for additional spent fuel dry storage system. It also need to safety classificate to spent fuel dry storage facilities in PWR, but there is no standard for safety classification of spent fuel dry storage facilities in China. Because the storage facilities of the spent fuel dry storage are not part of the NPP, the classification standard of China’s NPPs is not applicable. This paper proposes the safety classification suggestion of the spent fuel dry storage for China’s PWR NPP, through to the study on China’s safety classification principles of PWR NPP in “Classification for the items of pressurized water reactor nuclear power plants (GB/T 17569-2013)”, and safety classification about spent fuel dry storage system in NUREG/CR - 6407 in the United States.

  15. The Concise Guide to Pharmacology 2013/14: Enzymes

    PubMed Central

    Alexander, Stephen PH; Benson, Helen E; Faccenda, Elena; Pawson, Adam J; Sharman, Joanna L; Spedding, Michael; Peters, John A; Harmar, Anthony J

    2013-01-01

    The Concise Guide to PHARMACOLOGY 2013/14 provides concise overviews of the key properties of over 2000 human drug targets with their pharmacology, plus links to an open access knowledgebase of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. The full contents can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.12444/full. Enzymes are one of the seven major pharmacological targets into which the Guide is divided, with the others being G protein-coupled receptors, ligand-gated ion channels, ion channels, nuclear hormone receptors, catalytic receptors and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. A new landscape format has easy to use tables comparing related targets. It is a condensed version of material contemporary to late 2013, which is presented in greater detail and constantly updated on the website www.guidetopharmacology.org, superseding data presented in previous Guides to Receptors and Channels. It is produced in conjunction with NC-IUPHAR and provides the official IUPHAR classification and nomenclature for human drug targets, where appropriate. It consolidates information previously curated and displayed separately in IUPHAR-DB and the Guide to Receptors and Channels, providing a permanent, citable, point-in-time record that will survive database updates. PMID:24528243

  16. The Concise Guide to Pharmacology 2013/14: G Protein-Coupled Receptors

    PubMed Central

    Alexander, Stephen PH; Benson, Helen E; Faccenda, Elena; Pawson, Adam J; Sharman, Joanna L; Spedding, Michael; Peters, John A; Harmar, Anthony J

    2013-01-01

    The Concise Guide to PHARMACOLOGY 2013/14 provides concise overviews of the key properties of over 2000 human drug targets with their pharmacology, plus links to an open access knowledgebase of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. The full contents can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.12444/full. G protein-coupled receptors are one of the seven major pharmacological targets into which the Guide is divided, with the others being G protein-coupled receptors, ligand-gated ion channels, ion channels, catalytic receptors, nuclear hormone receptors, transporters and enzymes. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. A new landscape format has easy to use tables comparing related targets. It is a condensed version of material contemporary to late 2013, which is presented in greater detail and constantly updated on the website www.guidetopharmacology.org, superseding data presented in previous Guides to Receptors and Channels. It is produced in conjunction with NC-IUPHAR and provides the official IUPHAR classification and nomenclature for human drug targets, where appropriate. It consolidates information previously curated and displayed separately in IUPHAR-DB and the Guide to Receptors and Channels, providing a permanent, citable, point-in-time record that will survive database updates. PMID:24517644

  17. The Concise Guide to Pharmacology 2013/14: Transporters

    PubMed Central

    Alexander, Stephen PH; Benson, Helen E; Faccenda, Elena; Pawson, Adam J; Sharman, Joanna L; Spedding, Michael; Peters, John A; Harmar, Anthony J

    2013-01-01

    The Concise Guide to PHARMACOLOGY 2013/14 provides concise overviews of the key properties of over 2000 human drug targets with their pharmacology, plus links to an open access knowledgebase of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. The full contents can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.12444/full. Transporters are one of the seven major pharmacological targets into which the Guide is divided, with the others being G protein-coupled receptors, ligand-gated ion channels, ion channels, catalytic receptors, nuclear hormone receptors and enzymes. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. A new landscape format has easy to use tables comparing related targets. It is a condensed version of material contemporary to late 2013, which is presented in greater detail and constantly updated on the website www.guidetopharmacology.org, superseding data presented in previous Guides to Receptors and Channels. It is produced in conjunction with NC-IUPHAR and provides the official IUPHAR classification and nomenclature for human drug targets, where appropriate. It consolidates information previously curated and displayed separately in IUPHAR-DB and the Guide to Receptors and Channels, providing a permanent, citable, point-in-time record that will survive database updates. PMID:24528242

  18. Automated database-guided expert-supervised orientation for immunophenotypic diagnosis and classification of acute leukemia

    PubMed Central

    Lhermitte, L; Mejstrikova, E; van der Sluijs-Gelling, A J; Grigore, G E; Sedek, L; Bras, A E; Gaipa, G; Sobral da Costa, E; Novakova, M; Sonneveld, E; Buracchi, C; de Sá Bacelar, T; te Marvelde, J G; Trinquand, A; Asnafi, V; Szczepanski, T; Matarraz, S; Lopez, A; Vidriales, B; Bulsa, J; Hrusak, O; Kalina, T; Lecrevisse, Q; Martin Ayuso, M; Brüggemann, M; Verde, J; Fernandez, P; Burgos, L; Paiva, B; Pedreira, C E; van Dongen, J J M; Orfao, A; van der Velden, V H J

    2018-01-01

    Precise classification of acute leukemia (AL) is crucial for adequate treatment. EuroFlow has previously designed an AL orientation tube (ALOT) to guide towards the relevant classification panel (T-cell acute lymphoblastic leukemia (T-ALL), B-cell precursor (BCP)-ALL and/or acute myeloid leukemia (AML)) and final diagnosis. Now we built a reference database with 656 typical AL samples (145 T-ALL, 377 BCP-ALL, 134 AML), processed and analyzed via standardized protocols. Using principal component analysis (PCA)-based plots and automated classification algorithms for direct comparison of single-cells from individual patients against the database, another 783 cases were subsequently evaluated. Depending on the database-guided results, patients were categorized as: (i) typical T, B or Myeloid without or; (ii) with a transitional component to another lineage; (iii) atypical; or (iv) mixed-lineage. Using this automated algorithm, in 781/783 cases (99.7%) the right panel was selected, and data comparable to the final WHO-diagnosis was already provided in >93% of cases (85% T-ALL, 97% BCP-ALL, 95% AML and 87% mixed-phenotype AL patients), even without data on the full-characterization panels. Our results show that database-guided analysis facilitates standardized interpretation of ALOT results and allows accurate selection of the relevant classification panels, hence providing a solid basis for designing future WHO AL classifications. PMID:29089646

  19. 14 CFR 1203.412 - Classification guides.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... of the classification designations (i.e., Top Secret, Secret or Confidential) apply to the identified... writing by an official with original Top Secret classification authority; the identity of the official...

  20. 75 FR 3760 - Draft Regulatory Guide: Issuance, Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-22

    ... NUCLEAR REGULATORY COMMISSION [NRC-2010-0018] Draft Regulatory Guide: Issuance, Availability AGENCY: Nuclear Regulatory Commission. ACTION: Notice of Issuance and Availability of Draft Regulatory...) is issuing for public comment a draft guide in the agency's ``Regulatory Guide'' series. This series...

  1. 75 FR 20645 - Draft Regulatory Guide: Issuance, Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-20

    ... NUCLEAR REGULATORY COMMISSION [NRC-2010-0158] Draft Regulatory Guide: Issuance, Availability AGENCY: Nuclear Regulatory Commission. ACTION: Notice of Issuance and Availability of Draft Regulatory... draft guide in the agency's ``Regulatory Guide'' series. This series was developed to describe and make...

  2. 76 FR 189 - Final Regulatory Guide: Issuance, Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-03

    .../reading-rm/doc-collections/ . In addition, regulatory guides are available for inspection at the NRC's... NUCLEAR REGULATORY COMMISSION [NRC-2010-0265] Final Regulatory Guide: Issuance, Availability AGENCY: Nuclear Regulatory Commission. ACTION: Notice of Issuance and Availability of Regulatory Guide 3...

  3. 75 FR 5355 - Notice of Extension of Comment Period for NUREG-1934, Nuclear Power Plant Fire Modeling...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-02

    ..., Nuclear Power Plant Fire Modeling Application Guide (NPP FIRE MAG), Draft Report for Comment AGENCY... 1019195), Nuclear Power Plant Fire Modeling Application Guide (NPP FIRE MAG), Draft Report for Comment... Plant Fire Modeling Application Guide (NPP FIRE MAG)'' is available electronically under ADAMS Accession...

  4. 14 CFR 1203.408 - Assistance by installation security classification officers.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... ADMINISTRATION INFORMATION SECURITY PROGRAM Guides for Original Classification § 1203.408 Assistance by installation security classification officers. Installation Security Classification Officers, as the... 14 Aeronautics and Space 5 2011-01-01 2010-01-01 true Assistance by installation security...

  5. 14 CFR 1203.408 - Assistance by installation security classification officers.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... ADMINISTRATION INFORMATION SECURITY PROGRAM Guides for Original Classification § 1203.408 Assistance by installation security classification officers. Installation Security Classification Officers, as the... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Assistance by installation security...

  6. 75 FR 12804 - Withdrawal of Regulatory Guide 8.6

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-17

    ... NUCLEAR REGULATORY COMMISSION [NRC-2010-0103] Withdrawal of Regulatory Guide 8.6 AGENCY: Nuclear...[uuml]ller Counters.'' FOR FURTHER INFORMATION CONTACT: Harriet Karagiannis, U.S. Nuclear Regulatory... . SUPPLEMENTARY INFORMATION: I. Introduction The U.S. Nuclear Regulatory Commission (NRC) is withdrawing...

  7. 76 FR 6085 - Draft Regulatory Guide: Issuance, Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-03

    ...-2011-0014] RIN 3150-AI49 Draft Regulatory Guide: Issuance, Availability AGENCY: Nuclear Regulatory Commission. ACTION: Notice Availability of Draft Regulatory Guide. SUMMARY: The U.S. Nuclear Regulatory Commission (Commission or NRC) is issuing for public comment Draft Regulatory Guide, DG-5019, ``Reporting and...

  8. 75 FR 53352 - Draft Regulatory Guide: Issuance, Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-31

    ... Guide, DG-1247, ``Design-Basis Hurricane and Hurricane Missiles for Nuclear Power Plants.'' FOR FURTHER...'s ``Regulatory Guide'' series. This series was developed to describe and make available to the.... The draft regulatory guide (DG), entitled, ``Design-Basis Hurricane and Hurricane Missiles for Nuclear...

  9. 32 CFR 2001.22 - Derivative classification.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 6 2012-07-01 2012-07-01 false Derivative classification. 2001.22 Section 2001... Identification and Markings § 2001.22 Derivative classification. (a) General. Information classified derivatively on the basis of source documents or classification guides shall bear all markings prescribed in...

  10. 32 CFR 2001.22 - Derivative classification.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 6 2013-07-01 2013-07-01 false Derivative classification. 2001.22 Section 2001... Identification and Markings § 2001.22 Derivative classification. (a) General. Information classified derivatively on the basis of source documents or classification guides shall bear all markings prescribed in...

  11. 32 CFR 2001.22 - Derivative classification.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 6 2014-07-01 2014-07-01 false Derivative classification. 2001.22 Section 2001... Identification and Markings § 2001.22 Derivative classification. (a) General. Information classified derivatively on the basis of source documents or classification guides shall bear all markings prescribed in...

  12. 32 CFR 2001.22 - Derivative classification.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 6 2011-07-01 2011-07-01 false Derivative classification. 2001.22 Section 2001... Identification and Markings § 2001.22 Derivative classification. (a) General. Information classified derivatively on the basis of source documents or classification guides shall bear all markings prescribed in...

  13. The Dilemmas of Developing an Indigenous Advanced Arms Industry for Developing Countries: The Case of India and China

    DTIC Science & Technology

    2006-12-01

    of providing nuclear power. Once you have the nuclear weapons, they require a delivery system resulting in a missile program. It is afforded higher...out that some domestic advancements may be made in certain sectors, such as nuclear bombs and missiles, because resources may be spent on narrowly...capital, fighter, aviation, nuclear weapons, missiles 16. PRICE CODE 17. SECURITY CLASSIFICATION OF REPORT Unclassified 18. SECURITY CLASSIFICATION

  14. 77 FR 24228 - Condition Monitoring Techniques for Electric Cables Used in Nuclear Power Plants

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-23

    ... Used in Nuclear Power Plants AGENCY: Nuclear Regulatory Commission. ACTION: Regulatory guide; issuance... guide, (RG) 1.218, ``Condition Monitoring Techniques for Electric Cables Used in Nuclear Power Plants... of electric cables for nuclear power plants. RG 1.218 is not intended to be prescriptive, instead it...

  15. 76 FR 63541 - Design-Basis Hurricane and Hurricane Missiles for Nuclear Power Plants

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-13

    ... Hurricane Missiles for Nuclear Power Plants AGENCY: Nuclear Regulatory Commission. ACTION: Regulatory guide... regulatory guide, (RG) 1.221, ``Design-Basis Hurricane and Hurricane Missiles for Nuclear Power Plants... missiles that a nuclear power plant should be designed to withstand to prevent undue risk to the health and...

  16. Nuclear Dangers: A Resource Guide for Secondary School Teachers. Teaching Nuclear Issues.

    ERIC Educational Resources Information Center

    Meier, Paulette; McPherson, Beth

    Provided in this guide are annotated lists of teacher and student resources for teaching and learning about nuclear issues in the secondary school. Resources are grouped into five major sections. The first section (background reading for teachers) contains books and articles focusing on nuclear issues (nuclear war; arms race/disarmament; nuclear…

  17. 75 FR 43208 - Withdrawal of Regulatory Guide 5.17

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-23

    ... Engineering, Office of Nuclear Regulatory Research, U.S. Nuclear Regulatory Commission, Washington, DC 20555.... Introduction The U.S. Nuclear Regulatory Commission (NRC) is withdrawing Regulatory Guide 5.17, ``Truck... Development Branch, Division of Engineering, Office of Nuclear Regulatory Research. [FR Doc. 2010-18077 Filed...

  18. Applying a food processing-based classification system to a food guide: a qualitative analysis of the Brazilian experience.

    PubMed

    Davies, Vanessa Fernandes; Moubarac, Jean-Claude; Medeiros, Kharla Janinny; Jaime, Patricia Constante

    2018-01-01

    The present paper aimed to identify the stakeholders, as well as their arguments and recommendations, in the debate on the application of a food processing-based classification system to the new Brazilian Food Guide. Qualitative approach; an analysis was made of documents resulting from the consultation conducted for the development of the new Brazilian Food Guide, which uses the NOVA classification for its dietary recommendations. A thematic matrix was constructed and the resulting themes represented the main points for discussion raised during the consultation. Brazil. Actors from academia, government and associations/unions/professional bodies/organizations related to the area of nutrition and food security; non-profit institutions linked to consumer interests and civil society organizations; organizations, associations and food unions linked to the food industry; and individuals. Four themes were identified: (i) conflicting paradigms; (ii) different perceptions about the role and need of individuals; (iii) we want more from the new food guide; and (iv) a sustainable guide. There was extensive participation from different sectors of society. The debate generated by the consultation revealed two main conflicting opinions: a view aligned with the interests of the food industry and a view of healthy eating which serves the interests of the population. The first group was against the adoption of a food processing-based classification system in a public policy such as the new Brazilian Food Guide. The second group, although mostly agreeing with the new food guide, argued that it failed to address some important issues related to the food and nutrition agenda in Brazil.

  19. Evaluation of the Retrieval of Nuclear Science Document References Using the Universal Decimal Classification as the Indexing Language for a Computer-Based System

    ERIC Educational Resources Information Center

    Atherton, Pauline; And Others

    A single issue of Nuclear Science Abstracts, containing about 2,300 abstracts, was indexed by Universal Decimal Classification (UDC) using the Special Subject Edition of UDC for Nuclear Science and Technology. The descriptive cataloging and UDC-indexing records formed a computer-stored data base. A systematic random sample of 500 additional…

  20. 76 FR 55137 - Monitoring the Effectiveness of Maintenance at Nuclear Power Plants

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-06

    ... NUCLEAR REGULATORY COMMISSION [NRC-2011-0212] Monitoring the Effectiveness of Maintenance at... comment draft regulatory guide (DG) DG-1278, ``Monitoring the Effectiveness of Maintenance at Nuclear Power Plants.'' This guide endorses Revision 4A to Nuclear Management and Resources Council (NUMARC) 93...

  1. 76 FR 46856 - Qualification of Connection Assemblies for Nuclear Power Plants

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-03

    ... Power Plants AGENCY: Nuclear Regulatory Commission. ACTION: Regulatory guide; issuance. SUMMARY: The U.S..., ``Qualification of Connection Assemblies for Nuclear Power Plants.'' This guide describes a method that the NRC... in nuclear power plants. The environmental qualification helps ensure that connection assemblies can...

  2. Nuclear Technology Series. Radiation Protection Technician. A Suggested Program Planning Guide. Revised June 80.

    ERIC Educational Resources Information Center

    Center for Occupational Research and Development, Inc., Waco, TX.

    This program planning guide for a two-year postsecondary radiation protection technician program is designed for use with courses 17-22 of thirty-five included in the Nuclear Technology Series. The purpose of the guide is to describe the nuclear power field and its job categories for specialists, technicians, and operators; and to assist planners,…

  3. Common occupational classification system - revision 3

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Stahlman, E.J.; Lewis, R.E.

    1996-05-01

    Workforce planning has become an increasing concern within the DOE community as the Office of Environmental Restoration and Waste Management (ER/WM or EM) seeks to consolidate and refocus its activities and the Office of Defense Programs (DP) closes production sites. Attempts to manage the growth and skills mix of the EM workforce while retaining the critical skills of the DP workforce have been difficult due to the lack of a consistent set of occupational titles and definitions across the complex. Two reasons for this difficulty may be cited. First, classification systems commonly used in industry often fail to cover inmore » sufficient depth the unique demands of DOE`s nuclear energy and research community. Second, the government practice of contracting the operation of government facilities to the private sector has introduced numerous contractor-specific classification schemes to the DOE complex. As a result, sites/contractors report their workforce needs using unique classification systems. It becomes difficult, therefore, to roll these data up to the national level necessary to support strategic planning and analysis. The Common Occupational Classification System (COCS) is designed to overcome these workforce planning barriers. The COCS is based on earlier workforce planning activities and the input of technical, workforce planning, and human resource managers from across the DOE complex. It provides a set of mutually-exclusive occupation titles and definitions that cover the broad range of activities present in the DOE complex. The COCS is not a required record-keeping or data management guide. Neither is it intended to replace contractor/DOE-specific classification systems. Instead, the system provides a consistent, high- level, functional structure of occupations to which contractors can crosswalk (map) their job titles.« less

  4. 75 FR 52996 - Draft Regulatory Guide: Issuance, Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-30

    ... NUCLEAR REGULATORY COMMISSION [NRC-2010-0287] Draft Regulatory Guide: Issuance, Availability AGENCY: Nuclear Regulatory Commission. ACTION: Notice of issuance and availability of Draft Regulatory Guide, DG-8035, ``Administrative Practices in Radiation Surveys and Monitoring.'' FOR FURTHER...

  5. 76 FR 38212 - Notice of Issuance of Regulatory Guide

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-29

    ... NUCLEAR REGULATORY COMMISSION [NRC-2010-0275] Notice of Issuance of Regulatory Guide AGENCY: Nuclear Regulatory Commission. ACTION: Notice of Issuance and Availability of Revision 1 of Regulatory Guide (RG) 1.179, ``Standard Format [[Page 38213

  6. Classification of instability after reverse shoulder arthroplasty guides surgical management and outcomes.

    PubMed

    Abdelfattah, Adham; Otto, Randall J; Simon, Peter; Christmas, Kaitlyn N; Tanner, Gregory; LaMartina, Joey; Levy, Jonathan C; Cuff, Derek J; Mighell, Mark A; Frankle, Mark A

    2018-04-01

    Revision of unstable reverse shoulder arthroplasty (RSA) remains a significant challenge. The purpose of this study was to determine the reliability of a new treatment-guiding classification for instability after RSA, to describe the clinical outcomes of patients stabilized operatively, and to identify those with higher risk of recurrence. All patients undergoing revision for instability after RSA were identified at our institution. Demographic, clinical, radiographic, and intraoperative data were collected. A classification was developed using all identified causes of instability after RSA and allocating them to 1 of 3 defined treatment-guiding categories. Eight surgeons reviewed all data and applied the classification scheme to each case. Interobserver and intraobserver reliability was used to evaluate the classification scheme. Preoperative clinical outcomes were compared with final follow-up in stabilized shoulders. Forty-three revision cases in 34 patients met the inclusion for study. Five patients remained unstable after revision. Persistent instability most commonly occurred in persistent deltoid dysfunction and postoperative acromial fractures but also in 1 case of soft tissue impingement. Twenty-one patients remained stable at minimum 2 years of follow-up and had significant improvement of clinical outcome scores and range of motion. Reliability of the classification scheme showed substantial and almost perfect interobserver and intraobserver agreement among all the participants (κ = 0.699 and κ = 0.851, respectively). Instability after RSA can be successfully treated with revision surgery using the reliable treatment-guiding classification scheme presented herein. However, more understanding is needed for patients with greater risk of recurrent instability after revision surgery. Copyright © 2017 Journal of Shoulder and Elbow Surgery Board of Trustees. Published by Elsevier Inc. All rights reserved.

  7. Growing Up in a Nuclear World: A Resource Guide for Elementary School Teachers. Teaching Nuclear Issues.

    ERIC Educational Resources Information Center

    Meier, Paulette; McPherson, Beth

    Provided in this guide are annotated lists of teacher and student resources for teaching and learning about nuclear issues in the elementary/junior high school (grades K-8). Resources are grouped into five major sections. The first section (background reading for teachers) contains books and articles focusing on nuclear issues (nuclear war; arms…

  8. 76 FR 31382 - Notice of Issuance of Regulatory Guide

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-31

    ... NUCLEAR REGULATORY COMMISSION [NRC-2010-0287] Notice of Issuance of Regulatory Guide AGENCY: Nuclear Regulatory Commission. ACTION: Notice of Issuance and Availability of Regulatory Guide 8.2, Revision 1, ``Administrative Practices in Radiation Surveys and Monitoring.'' FOR FURTHER INFORMATION...

  9. 14 CFR 1203.405 - Proprietary information.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... PROGRAM Guides for Original Classification § 1203.405 Proprietary information. Proprietary information made available to NASA is subject to examination for classification purposes under the criteria set... the proposal but believes that security classification would be appropriate under the criteria of...

  10. 10 CFR 1045.13 - Classification prohibitions.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 4 2013-01-01 2013-01-01 false Classification prohibitions. 1045.13 Section 1045.13 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) NUCLEAR CLASSIFICATION AND DECLASSIFICATION Identification of Restricted Data and Formerly Restricted Data Information § 1045.13 Classification prohibitions...

  11. 10 CFR 1045.13 - Classification prohibitions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 4 2012-01-01 2012-01-01 false Classification prohibitions. 1045.13 Section 1045.13 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) NUCLEAR CLASSIFICATION AND DECLASSIFICATION Identification of Restricted Data and Formerly Restricted Data Information § 1045.13 Classification prohibitions...

  12. 10 CFR 1045.13 - Classification prohibitions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 4 2014-01-01 2014-01-01 false Classification prohibitions. 1045.13 Section 1045.13 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) NUCLEAR CLASSIFICATION AND DECLASSIFICATION Identification of Restricted Data and Formerly Restricted Data Information § 1045.13 Classification prohibitions...

  13. 10 CFR 1045.13 - Classification prohibitions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 4 2011-01-01 2011-01-01 false Classification prohibitions. 1045.13 Section 1045.13 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) NUCLEAR CLASSIFICATION AND DECLASSIFICATION Identification of Restricted Data and Formerly Restricted Data Information § 1045.13 Classification prohibitions...

  14. KWOC (Key-Word-Out-of-Context) Index of US Nuclear Regulatory Commission Regulatory Guide Series

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jennings, S.D.

    1990-04-01

    To meet the objectives of the program funded by the Department of Energy (DOE)-Nuclear Energy (NE) Technology Support Programs, the Performance Assurance Project Office (PAPO) administers a Performance Assurance Information Program that collects, compiles, and distributes program-related information, reports, and publications for the benefit of the DOE-NE program participants. THE KWOC Index of US Nuclear Regulatory Commission Regulatory Guide Series'' is prepared as an aid in searching for specific topics in the US Nuclear Regulatory Commission, Regulatory Guide Series.

  15. 76 FR 6086 - Draft Regulatory Guide: Issuance, Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-03

    ... NUCLEAR REGULATORY COMMISSION 10 CFR Part 73 [NRC-2011-0015] RIN 3150-AI49 Draft Regulatory Guide: Issuance, Availability AGENCY: Nuclear Regulatory Commission. ACTION: Notice of Availability of Draft... comment Draft Regulatory Guide, DG-5020, ``Applying for Enhanced Weapons Authority, Applying for...

  16. 75 FR 29785 - Draft Regulatory Guide: Issuance, Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-27

    ... Guide, DG-1248, ``Nuclear Power Plant Simulation Facilities for Use in Operator Training, License..., ``Nuclear Power Plant Simulation Facilities for Use in Operator Training, License Examinations, and... or acceptance of a nuclear power plant simulation facility for use in operator and senior operator...

  17. The Heart of Matter: A Nuclear Chemistry Module. Teacher's Guide.

    ERIC Educational Resources Information Center

    Viola, Vic; Hearle, Robert

    This teacher's guide is designed to provide science teachers with the necessary guidance and suggestions for teaching nuclear chemistry. In this book, the fundamental concepts of nuclear science and the applications of nuclear energy are discussed. The material in this book can be integrated with the other modules in a sequence that helps students…

  18. 76 FR 28102 - Notice of Issuance of Regulatory Guide

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-13

    ... Analysis, Office of Nuclear Regulatory Research, U.S. Nuclear Regulatory Commission, Washington, DC 20555... agency's ``Regulatory Guide'' series. This series was developed to describe and make available to the... guide. Licensees should identify how chosen approaches and methods (whether they are quantitative or...

  19. 75 FR 37842 - Notice of Issuance of Regulatory Guide

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-30

    ... INFORMATION CONTACT: R. A. Jervey, Regulatory Guide Development Branch, Division of Engineering, Office of...) 251-7404 or e-mail [email protected] . SUPPLEMENTARY INFORMATION: I. Introduction The U.S. Nuclear..., Regulatory Guide Development Branch, Division of Engineering, Office of Nuclear Regulatory Research. [FR Doc...

  20. Science, Society, and America's Nuclear Waste: The Nuclear Waste Policy Act, Unit 3. Teacher Guide. Second Edition.

    ERIC Educational Resources Information Center

    Department of Energy, Washington, DC. Office of Civilian Radioactive Waste Management, Washington, DC.

    This guide is Unit 3 of the four-part series, Science, Society, and America's Nuclear Waste, produced by the U.S. Department of Energy's Office of Civilian Radioactive Waste Management. The goal of this unit is to identify the key elements of the United States' nuclear waste dilemma and introduce the Nuclear Waste Policy Act and the role of the…

  1. 10 CFR 1045.8 - Procedural exemptions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Classification. (b) A request for an exemption shall be made in writing to the Director of Classification and... DEPARTMENT OF ENERGY (GENERAL PROVISIONS) NUCLEAR CLASSIFICATION AND DECLASSIFICATION Program Management of the Restricted Data and Formerly Restricted Data Classification System § 1045.8 Procedural exemptions...

  2. 10 CFR 1045.8 - Procedural exemptions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Classification. (b) A request for an exemption shall be made in writing to the Director of Classification and... DEPARTMENT OF ENERGY (GENERAL PROVISIONS) NUCLEAR CLASSIFICATION AND DECLASSIFICATION Program Management of the Restricted Data and Formerly Restricted Data Classification System § 1045.8 Procedural exemptions...

  3. 14 CFR 1203.407 - Duration of classification.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 1203.407 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION INFORMATION SECURITY PROGRAM Guides for Original Classification § 1203.407 Duration of classification. (a) Information shall be classified as long as required by national security considerations. When it can be determined, a specific...

  4. 14 CFR 1203.407 - Duration of classification.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Section 1203.407 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION INFORMATION SECURITY PROGRAM Guides for Original Classification § 1203.407 Duration of classification. (a) Information shall be classified as long as required by national security considerations. When it can be determined, a specific...

  5. 75 FR 28073 - Draft Regulatory Guide: Issuance, Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-19

    ... NUCLEAR REGULATORY COMMISSION [NRC-2010-0181] Draft Regulatory Guide: Issuance, Availability AGENCY: Nuclear Regulatory Commission. ACTION: Notice of Issuance and Availability of Draft Regulatory Guide, DG-3039, ``Standard Format and Content for Emergency Plans for Fuel Cycle and Materials Facilities.'' FOR FURTHER INFORMATION CONTACT: Kevin M....

  6. 76 FR 2726 - Withdrawal of Regulatory Guide 1.154

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-14

    ... NUCLEAR REGULATORY COMMISSION [NRC-2011-0010] Withdrawal of Regulatory Guide 1.154 AGENCY: Nuclear Regulatory Commission. ACTION: Withdrawal of Regulatory Guide 1.154, ``Format and Content of Plant-Specific Pressurized Thermal Shock Safety Analysis Reports for Pressurized Water Reactors.'' FOR FURTHER INFORMATION CONTACT: Mekonen M. Bayssie,...

  7. 76 FR 24539 - Final Regulatory Guide: Issuance, Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-02

    ... NUCLEAR REGULATORY COMMISSION [NRC-2010-0181] Final Regulatory Guide: Issuance, Availability AGENCY: Nuclear Regulatory Commission. ACTION: Notice of Issuance and Availability of Regulatory Guide (RG) 3.67, ``Standard Format and Content for Emergency Plans for Fuel Cycle and Materials Facilities.'' FOR FURTHER INFORMATION CONTACT: Kevin M. Ramse...

  8. Science, Society, and America's Nuclear Waste: Nuclear Waste, Unit 1. Teacher Guide. Second Edition.

    ERIC Educational Resources Information Center

    Department of Energy, Washington, DC. Office of Civilian Radioactive Waste Management, Washington, DC.

    This guide is Unit 1 of the four-part series Science, Society, and America's Nuclear Waste produced by the U.S. Department of Energy's Office of Civilian Radioactive Waste Management. The goal of this unit is to help students establish the relevance of the topic of nuclear waste to their everyday lives and activities. Particular attention is…

  9. Understanding Nuclear Weapons and Arms Control: A Guide to the Issues. New Edition.

    ERIC Educational Resources Information Center

    Mayers, Teena

    Intended for secondary and college level students and teachers, this guide discusses the nuclear arms control issue. There are four sections. Section I discusses U.S. nuclear strategy from 1945 to the present, strategic nuclear weapons competition between the United States and the Union of Soviet Socialist Republics (U.S.S.R.), U.S.…

  10. Hypothesis-driven classification of materials using nuclear magnetic resonance relaxometry

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Espy, Michelle A.; Matlashov, Andrei N.; Schultz, Larry J.

    Technologies related to identification of a substance in an optimized manner are provided. A reference group of known materials is identified. Each known material has known values for several classification parameters. The classification parameters comprise at least one of T.sub.1, T.sub.2, T.sub.1.rho., a relative nuclear susceptibility (RNS) of the substance, and an x-ray linear attenuation coefficient (LAC) of the substance. A measurement sequence is optimized based on at least one of a measurement cost of each of the classification parameters and an initial probability of each of the known materials in the reference group.

  11. 10 CFR 1045.39 - Challenging classification and declassification determinations.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ..., a further appeal may be made to the Chief Health, Safety and Security Officer. (c) Classification... 10 Energy 4 2011-01-01 2011-01-01 false Challenging classification and declassification determinations. 1045.39 Section 1045.39 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) NUCLEAR CLASSIFICATION...

  12. 10 CFR 1045.19 - Accountability for classification and declassification determinations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... classification or declassification determination concerning RD or FRD information is made, the Director of... 10 Energy 4 2010-01-01 2010-01-01 false Accountability for classification and declassification determinations. 1045.19 Section 1045.19 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) NUCLEAR CLASSIFICATION...

  13. 10 CFR 1045.39 - Challenging classification and declassification determinations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ..., a further appeal may be made to the Chief Health, Safety and Security Officer. (c) Classification... 10 Energy 4 2010-01-01 2010-01-01 false Challenging classification and declassification determinations. 1045.39 Section 1045.39 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) NUCLEAR CLASSIFICATION...

  14. 10 CFR 1045.19 - Accountability for classification and declassification determinations.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... classification or declassification determination concerning RD or FRD information is made, the Director of... 10 Energy 4 2011-01-01 2011-01-01 false Accountability for classification and declassification determinations. 1045.19 Section 1045.19 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) NUCLEAR CLASSIFICATION...

  15. 10 CFR 61.55 - Waste classification.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 2 2014-01-01 2014-01-01 false Waste classification. 61.55 Section 61.55 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR LAND DISPOSAL OF RADIOACTIVE WASTE Technical Requirements for Land Disposal Facilities § 61.55 Waste classification. (a) Classification of waste for near...

  16. 10 CFR 61.55 - Waste classification.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 2 2012-01-01 2012-01-01 false Waste classification. 61.55 Section 61.55 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR LAND DISPOSAL OF RADIOACTIVE WASTE Technical Requirements for Land Disposal Facilities § 61.55 Waste classification. (a) Classification of waste for near...

  17. 10 CFR 61.55 - Waste classification.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 2 2013-01-01 2013-01-01 false Waste classification. 61.55 Section 61.55 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR LAND DISPOSAL OF RADIOACTIVE WASTE Technical Requirements for Land Disposal Facilities § 61.55 Waste classification. (a) Classification of waste for near...

  18. Matching Three Classifications of Secondary Students to Differential Levels of Study Guides.

    ERIC Educational Resources Information Center

    Horton, Steven V.; And Others

    1991-01-01

    This study examined the effectiveness of matching 82 secondary students (learning disabled, remedial, and nondisabled) to differential levels of study guides. The study evaluated two treatment conditions (multilevel study guides containing different levels of referential cues, and single-level study guides without referential cues), used in…

  19. Nuclear Medicine Technology: A Suggested Postsecondary Curriculum.

    ERIC Educational Resources Information Center

    Technical Education Research Center, Cambridge, MA.

    The purpose of this curriculum guide is to assist administrators and instructors in establishing nuclear medicine technician programs that will meet the accreditation standards of the American Medical Association (AMA) Council on Medical Education. The guide has been developed to prepare nuclear medicine technicians (NMT's) in two-year…

  20. 75 FR 16202 - Notice of Issuance of Regulatory Guide

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-31

    ..., Revision 2, ``An Acceptable Model and Related Statistical Methods for the Analysis of Fuel Densification.... Introduction The U.S. Nuclear Regulatory Commission (NRC) is issuing a revision to an existing guide in the... nuclear power reactors. To meet these objectives, the guide describes statistical methods related to...

  1. 6 CFR 7.28 - Automatic declassification.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Classification Appeals Panel (ISCAP) for approval. (d) Declassification guides that narrowly and precisely define... years after the date of its original classification with the exception of specific information exempt...

  2. 75 FR 36715 - Final Regulatory Guide: Issuance, Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-28

    ... INFORMATION: I. Introduction The U.S. Nuclear Regulatory Commission (NRC or Commission) is issuing a revision..., Chief, Regulatory Guide Development Branch, Division of Engineering, Office of Nuclear Regulatory...

  3. THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Overview.

    PubMed

    Alexander, Stephen Ph; Kelly, Eamonn; Marrion, Neil V; Peters, John A; Faccenda, Elena; Harding, Simon D; Pawson, Adam J; Sharman, Joanna L; Southan, Christopher; Buneman, O Peter; Cidlowski, John A; Christopoulos, Arthur; Davenport, Anthony P; Fabbro, Doriano; Spedding, Michael; Striessnig, Jörg; Davies, Jamie A

    2017-12-01

    The Concise Guide to PHARMACOLOGY 2017/18 is the third in this series of biennial publications. This version provides concise overviews of the key properties of nearly 1800 human drug targets with an emphasis on selective pharmacology (where available), plus links to an open access knowledgebase of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. Although the Concise Guide represents approximately 400 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point-in-time record that will survive database updates. The full contents of this section can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.13882/full. In addition to this overview, in which are identified 'Other protein targets' which fall outside of the subsequent categorisation, there are eight areas of focus: G protein-coupled receptors, ligand-gated ion channels, voltage-gated ion channels, other ion channels, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid-2017, and supersedes data presented in the 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the Nomenclature Committee of the Union of Basic and Clinical Pharmacology (NC-IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate. © 2017 The Authors. British Journal of Pharmacology published by John Wiley & Sons Ltd on behalf of British Pharmacological Society.

  4. The Concise Guide to PHARMACOLOGY 2015/16: Overview.

    PubMed

    Alexander, Stephen Ph; Kelly, Eamonn; Marrion, Neil; Peters, John A; Benson, Helen E; Faccenda, Elena; Pawson, Adam J; Sharman, Joanna L; Southan, Christopher; Buneman, O Peter; Catterall, William A; Cidlowski, John A; Davenport, Anthony P; Fabbro, Doriano; Fan, Grace; McGrath, John C; Spedding, Michael; Davies, Jamie A

    2015-12-01

    The Concise Guide to PHARMACOLOGY 2015/16 provides concise overviews of the key properties of over 1750 human drug targets with their pharmacology, plus links to an open access knowledgebase of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. The full contents can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.13347/full. This compilation of the major pharmacological targets is divided into eight areas of focus: G protein-coupled receptors, ligand-gated ion channels, voltage-gated ion channels, other ion channels, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The Concise Guide is published in landscape format in order to facilitate comparison of related targets. It is a condensed version of material contemporary to late 2015, which is presented in greater detail and constantly updated on the website www.guidetopharmacology.org, superseding data presented in the previous Guides to Receptors & Channels and the Concise Guide to PHARMACOLOGY 2013/14. It is produced in conjunction with NC-IUPHAR and provides the official IUPHAR classification and nomenclature for human drug targets, where appropriate. It consolidates information previously curated and displayed separately in IUPHAR-DB and GRAC and provides a permanent, citable, point-in-time record that will survive database updates. © 2015 The Authors. British Journal of Pharmacology published by John Wiley & Sons Ltd on behalf of The British Pharmacological Society.

  5. 10 CFR 1045.14 - Process for classification and declassification of restricted data and formerly restricted data...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Process for classification and declassification of... (GENERAL PROVISIONS) NUCLEAR CLASSIFICATION AND DECLASSIFICATION Identification of Restricted Data and Formerly Restricted Data Information § 1045.14 Process for classification and declassification of...

  6. 10 CFR 1045.14 - Process for classification and declassification of restricted data and formerly restricted data...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 4 2014-01-01 2014-01-01 false Process for classification and declassification of... (GENERAL PROVISIONS) NUCLEAR CLASSIFICATION AND DECLASSIFICATION Identification of Restricted Data and Formerly Restricted Data Information § 1045.14 Process for classification and declassification of...

  7. 10 CFR 1045.14 - Process for classification and declassification of restricted data and formerly restricted data...

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 4 2013-01-01 2013-01-01 false Process for classification and declassification of... (GENERAL PROVISIONS) NUCLEAR CLASSIFICATION AND DECLASSIFICATION Identification of Restricted Data and Formerly Restricted Data Information § 1045.14 Process for classification and declassification of...

  8. 10 CFR 1045.14 - Process for classification and declassification of restricted data and formerly restricted data...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 4 2012-01-01 2012-01-01 false Process for classification and declassification of... (GENERAL PROVISIONS) NUCLEAR CLASSIFICATION AND DECLASSIFICATION Identification of Restricted Data and Formerly Restricted Data Information § 1045.14 Process for classification and declassification of...

  9. 75 FR 43207 - Notice of Issuance of Regulatory Guide

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-23

    ... INFORMATION: I. Introduction The U.S. Nuclear Regulatory Commission (NRC) is issuing a revision to an existing.... Jervey, Acting Chief, Regulatory Guide Development Branch, Division of Engineering, Office of Nuclear...

  10. Principles of Guided Missiles and Nuclear Weapons.

    ERIC Educational Resources Information Center

    Naval Personnel Program Support Activity, Washington, DC.

    Fundamentals of missile and nuclear weapons systems are presented in this book which is primarily prepared as the second text of a three-volume series for students of the Navy Reserve Officers' Training Corps and the Officer Candidate School. Following an introduction to guided missiles and nuclear physics, basic principles and theories are…

  11. 78 FR 35330 - Initial Test Programs for Water-Cooled Nuclear Power Plants

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-12

    ... this notice is provided the first time that a document is referenced. Revision 4 of Regulatory Guide 1... FURTHER INFORMATION CONTACT: Mark Orr, Office of Nuclear Regulatory Research, U.S. Nuclear Regulatory... Guide'' series. This series was developed to describe and make available to the public information such...

  12. Quantification of the Spatial Organization of the Nuclear Lamina as a Tool for Cell Classification

    PubMed Central

    Righolt, Christiaan H.; Zatreanu, Diana A.; Raz, Vered

    2013-01-01

    The nuclear lamina is the structural scaffold of the nuclear envelope that plays multiple regulatory roles in chromatin organization and gene expression as well as a structural role in nuclear stability. The lamina proteins, also referred to as lamins, determine nuclear lamina organization and define the nuclear shape and the structural integrity of the cell nucleus. In addition, lamins are connected with both nuclear and cytoplasmic structures forming a dynamic cellular structure whose shape changes upon external and internal signals. When bound to the nuclear lamina, the lamins are mobile, have an impact on the nuclear envelop structure, and may induce changes in their regulatory functions. Changes in the nuclear lamina shape cause changes in cellular functions. A quantitative description of these structural changes could provide an unbiased description of changes in cellular function. In this review, we describe how changes in the nuclear lamina can be measured from three-dimensional images of lamins at the nuclear envelope, and we discuss how structural changes of the nuclear lamina can be used for cell classification. PMID:27335676

  13. Quantification of the Spatial Organization of the Nuclear Lamina as a Tool for Cell Classification.

    PubMed

    Righolt, Christiaan H; Zatreanu, Diana A; Raz, Vered

    2013-01-01

    The nuclear lamina is the structural scaffold of the nuclear envelope that plays multiple regulatory roles in chromatin organization and gene expression as well as a structural role in nuclear stability. The lamina proteins, also referred to as lamins, determine nuclear lamina organization and define the nuclear shape and the structural integrity of the cell nucleus. In addition, lamins are connected with both nuclear and cytoplasmic structures forming a dynamic cellular structure whose shape changes upon external and internal signals. When bound to the nuclear lamina, the lamins are mobile, have an impact on the nuclear envelop structure, and may induce changes in their regulatory functions. Changes in the nuclear lamina shape cause changes in cellular functions. A quantitative description of these structural changes could provide an unbiased description of changes in cellular function. In this review, we describe how changes in the nuclear lamina can be measured from three-dimensional images of lamins at the nuclear envelope, and we discuss how structural changes of the nuclear lamina can be used for cell classification.

  14. 10 CFR 1045.17 - Classification levels.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... classification include detailed technical descriptions of critical features of a nuclear explosive design that... classification include designs for specific weapon components (not revealing critical features), key features of uranium enrichment technologies, or specifications of weapon materials. (3) Confidential. The Director of...

  15. 10 CFR 1045.17 - Classification levels.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... classification include detailed technical descriptions of critical features of a nuclear explosive design that... classification include designs for specific weapon components (not revealing critical features), key features of uranium enrichment technologies, or specifications of weapon materials. (3) Confidential. The Director of...

  16. 10 CFR 1045.17 - Classification levels.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... classification include detailed technical descriptions of critical features of a nuclear explosive design that... classification include designs for specific weapon components (not revealing critical features), key features of uranium enrichment technologies, or specifications of weapon materials. (3) Confidential. The Director of...

  17. 10 CFR 1045.17 - Classification levels.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... classification include detailed technical descriptions of critical features of a nuclear explosive design that... classification include designs for specific weapon components (not revealing critical features), key features of uranium enrichment technologies, or specifications of weapon materials. (3) Confidential. The Director of...

  18. 10 CFR 1045.3 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... ENERGY (GENERAL PROVISIONS) NUCLEAR CLASSIFICATION AND DECLASSIFICATION Program Management of the Restricted Data and Formerly Restricted Data Classification System § 1045.3 Definitions. As used in this part...) The expiration of a maximum time frame for duration of classification established under Executive...

  19. 10 CFR 1045.3 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... ENERGY (GENERAL PROVISIONS) NUCLEAR CLASSIFICATION AND DECLASSIFICATION Program Management of the Restricted Data and Formerly Restricted Data Classification System § 1045.3 Definitions. As used in this part...) The expiration of a maximum time frame for duration of classification established under Executive...

  20. 10 CFR 1045.3 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... ENERGY (GENERAL PROVISIONS) NUCLEAR CLASSIFICATION AND DECLASSIFICATION Program Management of the Restricted Data and Formerly Restricted Data Classification System § 1045.3 Definitions. As used in this part...) The expiration of a maximum time frame for duration of classification established under Executive...

  1. Map Classification: A Comparison of Schemes with Special Reference to the Continent of Africa. Occasional Papers, Number 154.

    ERIC Educational Resources Information Center

    Merrett, Christopher E.

    This guide to the theory and practice of map classification begins with a discussion of the filing of maps and the function of map classification based on area and theme as illustrated by four maps of Africa. The description of the various classification systems which follows is divided into book schemes with provision for maps (including Dewey…

  2. Land cover change detection using a GIS-guided, feature-based classification of Landsat thematic mapper data. [Geographic Information System

    NASA Technical Reports Server (NTRS)

    Enslin, William R.; Ton, Jezching; Jain, Anil

    1987-01-01

    Landsat TM data were combined with land cover and planimetric data layers contained in the State of Michigan's geographic information system (GIS) to identify changes in forestlands, specifically new oil/gas wells. A GIS-guided feature-based classification method was developed. The regions extracted by the best image band/operator combination were studied using a set of rules based on the characteristics of the GIS oil/gas pads.

  3. 10 CFR 1045.14 - Process for classification and declassification of restricted data and formerly restricted data...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Classification shall determine whether the information is RD within 90 days of receipt by doing the following: (i... 10 Energy 4 2011-01-01 2011-01-01 false Process for classification and declassification of... (GENERAL PROVISIONS) NUCLEAR CLASSIFICATION AND DECLASSIFICATION Identification of Restricted Data and...

  4. Nuclear Age Issues: A Teacher's Resource Guide for Kindergarten through Grade Twelve. Publication No. X-127.

    ERIC Educational Resources Information Center

    Los Angeles Unified School District, CA. Office of Instruction.

    This teacher's resource guide is designed to facilitate the planning of science and history/social science classroom instruction concerning nuclear age issues for elementary and secondary students. The materials introduce this topic with an interdisciplinary approach to a broad range of nuclear topics. The booklet is divided into five sections.…

  5. Linear Classification of Dairy Cattle. Slide Script.

    ERIC Educational Resources Information Center

    Sipiorski, James; Spike, Peter

    This slide script, part of a series of slide scripts designed for use in vocational agriculture classes, deals with principles of the linear classification of dairy cattle. Included in the guide are narrations for use with 63 slides, which illustrate the following areas that are considered in the linear classification system: stature, strength,…

  6. 10 CFR 1045.40 - Marking requirements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... DEPARTMENT OF ENERGY (GENERAL PROVISIONS) NUCLEAR CLASSIFICATION AND DECLASSIFICATION Generation and Review... holder that it contains RD or FRD information, the level of classification assigned, and the additional... classification level of the document, the following notices shall appear on the front of the document, as...

  7. 10 CFR 1045.40 - Marking requirements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... DEPARTMENT OF ENERGY (GENERAL PROVISIONS) NUCLEAR CLASSIFICATION AND DECLASSIFICATION Generation and Review... holder that it contains RD or FRD information, the level of classification assigned, and the additional... classification level of the document, the following notices shall appear on the front of the document, as...

  8. 78 FR 58574 - Maintenance, Testing, and Replacement of Vented Lead-Acid Storage Batteries for Nuclear Power Plants

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-24

    ... time that a document is referenced. Revision 3 of Regulatory Guide 1.129 is available in ADAMS under...-251-7455; email: [email protected] . Both of the Office of Nuclear Regulatory Research, U.S... NRC is issuing a revision to an existing guide in the NRC's ``Regulatory Guide'' series. This series...

  9. Development and initial validation of the Classification of Early-Onset Scoliosis (C-EOS).

    PubMed

    Williams, Brendan A; Matsumoto, Hiroko; McCalla, Daren J; Akbarnia, Behrooz A; Blakemore, Laurel C; Betz, Randal R; Flynn, John M; Johnston, Charles E; McCarthy, Richard E; Roye, David P; Skaggs, David L; Smith, John T; Snyder, Brian D; Sponseller, Paul D; Sturm, Peter F; Thompson, George H; Yazici, Muharrem; Vitale, Michael G

    2014-08-20

    Early-onset scoliosis is a heterogeneous condition, with highly variable manifestations and natural history. No standardized classification system exists to describe and group patients, to guide optimal care, or to prognosticate outcomes within this population. A classification system for early-onset scoliosis is thus a necessary prerequisite to the timely evolution of care of these patients. Fifteen experienced surgeons participated in a nominal group technique designed to achieve a consensus-based classification system for early-onset scoliosis. A comprehensive list of factors important in managing early-onset scoliosis was generated using a standardized literature review, semi-structured interviews, and open forum discussion. Three group meetings and two rounds of surveying guided the selection of classification components, subgroupings, and cut-points. Initial validation of the system was conducted using an interobserver reliability assessment based on the classification of a series of thirty cases. Nominal group technique was used to identify three core variables (major curve angle, etiology, and kyphosis) with high group content validity scores. Age and curve progression ranked slightly lower. Participants evaluated the cases of thirty patients with early-onset scoliosis for reliability testing. The mean kappa value for etiology (0.64) was substantial, while the mean kappa values for major curve angle (0.95) and kyphosis (0.93) indicated almost perfect agreement. The final classification consisted of a continuous age prefix, etiology (congenital or structural, neuromuscular, syndromic, and idiopathic), major curve angle (1, 2, 3, or 4), and kyphosis (-, N, or +) variables, and an optional progression modifier (P0, P1, or P2). Utilizing formal consensus-building methods in a large group of surgeons experienced in treating early-onset scoliosis, a novel classification system for early-onset scoliosis was developed with all core components demonstrating substantial to excellent interobserver reliability. This classification system will serve as a foundation to guide ongoing research efforts and standardize communication in the clinical setting. Copyright © 2014 by The Journal of Bone and Joint Surgery, Incorporated.

  10. Vehicle classification system : FHWA perspective

    DOT National Transportation Integrated Search

    2000-08-01

    Issues related to vehicle classification in light of the Federal Highway Administration (FHWA) Traffic Monitoring Guide (TMG) revision will be discussed. The discussion will look at the expressed needs of the data users and the associated impacts on ...

  11. Feasibility of clinical detection of cervical dysplasia using angle-resolved low coherence interferometry measurements of depth-resolved nuclear morphology.

    PubMed

    Ho, Derek; Drake, Tyler K; Smith-McCune, Karen K; Darragh, Teresa M; Hwang, Loris Y; Wax, Adam

    2017-03-15

    This study sought to establish the feasibility of using in situ depth-resolved nuclear morphology measurements for detection of cervical dysplasia. Forty enrolled patients received routine cervical colposcopy with angle-resolved low coherence interferometry (a/LCI) measurements of nuclear morphology. a/LCI scans from 63 tissue sites were compared to histopathological analysis of co-registered biopsy specimens which were classified as benign, low-grade squamous intraepithelial lesion (LSIL), or high-grade squamous intraepithelial lesion (HSIL). Results were dichotomized as dysplastic (LSIL/HSIL) versus non-dysplastic and HSIL versus LSIL/benign to determine both accuracy and potential clinical utility of a/LCI nuclear morphology measurements. Analysis of a/LCI data was conducted using both traditional Mie theory based processing and a new hybrid algorithm that provides improved processing speed to ascertain the feasibility of real-time measurements. Analysis of depth-resolved nuclear morphology data revealed a/LCI was able to detect a significant increase in the nuclear diameter at the depth bin containing the basal layer of the epithelium for dysplastic versus non-dysplastic and HSIL versus LSIL/Benign biopsy sites (both p < 0.001). Both processing techniques resulted in high sensitivity and specificity (>0.80) in identifying dysplastic biopsies and HSIL. The hybrid algorithm demonstrated a threefold decrease in processing time at a slight cost in classification accuracy. The results demonstrate the feasibility of using a/LCI as an adjunctive clinical tool for detecting cervical dysplasia and guiding the identification of optimal biopsy sites. The faster speed from the hybrid algorithm offers a promising approach for real-time clinical analysis. © 2016 UICC.

  12. Feasibility of clinical detection of cervical dysplasia using angle-resolved low coherence interferometry measurements of depth-resolved nuclear morphology

    PubMed Central

    Ho, Derek; Drake, Tyler K.; Smith-McCune, Karen K.; Darragh, Teresa M.; Hwang, Loris Y.; Wax, Adam

    2017-01-01

    This study sought to establish the feasibility of using in situ depth-resolved nuclear morphology measurements for detection of cervical dysplasia. Forty (40) enrolled patients received routine cervical colposcopy with angle-resolved low coherence interferometry (a/LCI) measurements of nuclear morphology. a/LCI scans from 63 tissue sites were compared to histopathological analysis of co-registered biopsy specimens which were classified as benign, low-grade squamous intraepithelial lesion (LSIL), or high-grade squamous intraepithelial lesion (HSIL). Results were dichotomized as dysplastic (LSIL/HSIL) versus non-dysplastic and HSIL versus LSIL/benign to determine both accuracy and potential clinical utility of a/LCI nuclear morphology measurements. Analysis of a/LCI data was conducted using both traditional Mie theory based processing and a new hybrid algorithm that provides improved processing speed to ascertain the feasibility of real-time measurements. Analysis of depth-resolved nuclear morphology data revealed a/LCI was able to detect a significant increase in the nuclear diameter at the depth bin containing the basal layer of the epithelium for dysplastic versus non-dysplastic and HSIL versus LSIL/Benign biopsy sites (both p < 0.001). Both processing techniques resulted in high sensitivity and specificity (> 0.80) in identifying dysplastic biopsies and HSIL. The hybrid algorithm demonstrated a threefold decrease in processing time at a slight cost in classification accuracy. The results demonstrate the feasibility of using a/LCI as an adjunctive clinical tool for detecting cervical dysplasia and guiding the identification of optimal biopsy sites. The faster speed from the hybrid algorithm offers a promising approach for real-time clinical analysis. PMID:27883177

  13. Traffic monitoring guide

    DOT National Transportation Integrated Search

    1995-02-01

    This guide is designed to provide direction on the monitoring of traffic characteristics. It begins with a discussion of the structure of traffic characteristics monitoring and traffic counting. The next two sections cover vehicle classification and ...

  14. Supervised Semantic Classification for Nuclear Proliferation Monitoring

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Vatsavai, Raju; Cheriyadat, Anil M; Gleason, Shaun Scott

    2010-01-01

    Existing feature extraction and classification approaches are not suitable for monitoring proliferation activity using high-resolution multi-temporal remote sensing imagery. In this paper we present a supervised semantic labeling framework based on the Latent Dirichlet Allocation method. This framework is used to analyze over 120 images collected under different spatial and temporal settings over the globe representing three major semantic categories: airports, nuclear, and coal power plants. Initial experimental results show a reasonable discrimination of these three categories even though coal and nuclear images share highly common and overlapping objects. This research also identified several research challenges associated with nuclear proliferationmore » monitoring using high resolution remote sensing images.« less

  15. 21 CFR 892.1400 - Nuclear sealed calibration source.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... reference radionuclide intended for calibration of medical nuclear radiation detectors. (b) Classification... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Nuclear sealed calibration source. 892.1400... (CONTINUED) MEDICAL DEVICES RADIOLOGY DEVICES Diagnostic Devices § 892.1400 Nuclear sealed calibration source...

  16. 21 CFR 892.1400 - Nuclear sealed calibration source.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... reference radionuclide intended for calibration of medical nuclear radiation detectors. (b) Classification... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Nuclear sealed calibration source. 892.1400... (CONTINUED) MEDICAL DEVICES RADIOLOGY DEVICES Diagnostic Devices § 892.1400 Nuclear sealed calibration source...

  17. 21 CFR 892.1400 - Nuclear sealed calibration source.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... reference radionuclide intended for calibration of medical nuclear radiation detectors. (b) Classification... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Nuclear sealed calibration source. 892.1400... (CONTINUED) MEDICAL DEVICES RADIOLOGY DEVICES Diagnostic Devices § 892.1400 Nuclear sealed calibration source...

  18. 21 CFR 892.1400 - Nuclear sealed calibration source.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... reference radionuclide intended for calibration of medical nuclear radiation detectors. (b) Classification... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Nuclear sealed calibration source. 892.1400... (CONTINUED) MEDICAL DEVICES RADIOLOGY DEVICES Diagnostic Devices § 892.1400 Nuclear sealed calibration source...

  19. 21 CFR 892.1400 - Nuclear sealed calibration source.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... reference radionuclide intended for calibration of medical nuclear radiation detectors. (b) Classification... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Nuclear sealed calibration source. 892.1400... (CONTINUED) MEDICAL DEVICES RADIOLOGY DEVICES Diagnostic Devices § 892.1400 Nuclear sealed calibration source...

  20. Semantic and topological classification of images in magnetically guided capsule endoscopy

    NASA Astrophysics Data System (ADS)

    Mewes, P. W.; Rennert, P.; Juloski, A. L.; Lalande, A.; Angelopoulou, E.; Kuth, R.; Hornegger, J.

    2012-03-01

    Magnetically-guided capsule endoscopy (MGCE) is a nascent technology with the goal to allow the steering of a capsule endoscope inside a water filled stomach through an external magnetic field. We developed a classification cascade for MGCE images with groups images in semantic and topological categories. Results can be used in a post-procedure review or as a starting point for algorithms classifying pathologies. The first semantic classification step discards over-/under-exposed images as well as images with a large amount of debris. The second topological classification step groups images with respect to their position in the upper gastrointestinal tract (mouth, esophagus, stomach, duodenum). In the third stage two parallel classifications steps distinguish topologically different regions inside the stomach (cardia, fundus, pylorus, antrum, peristaltic view). For image classification, global image features and local texture features were applied and their performance was evaluated. We show that the third classification step can be improved by a bubble and debris segmentation because it limits feature extraction to discriminative areas only. We also investigated the impact of segmenting intestinal folds on the identification of different semantic camera positions. The results of classifications with a support-vector-machine show the significance of color histogram features for the classification of corrupted images (97%). Features extracted from intestinal fold segmentation lead only to a minor improvement (3%) in discriminating different camera positions.

  1. Classification of materials using nuclear magnetic resonance dispersion and/or x-ray absorption

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Espy, Michelle A.; Matlashov, Andrei N.; Schultz, Larry J.

    Methods for determining the identity of a substance are provided. A classification parameter set is defined to allow identification of substances that previously could not be identified or to allow identification of substances with a higher degree of confidence. The classification parameter set may include at least one of relative nuclear susceptibility (RNS) or an x-ray linear attenuation coefficient (LAC). RNS represents the density of hydrogen nuclei present in a substance relative to the density of hydrogen nuclei present in water. The extended classification parameter set may include T.sub.1, T.sub.2, and/or T.sub.1.rho. as well as at least one additional classificationmore » parameter comprising one of RNS or LAC. Values obtained for additional classification parameters as well as values obtained for T.sub.1, T.sub.2, and T.sub.1.rho. can be compared to known classification parameter values to determine whether a particular substance is a known material.« less

  2. Guide for the preparation of applications for Nuclear Pharmacy Licenses

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1985-08-01

    The purpose of this regulatory guide is to provide assistance to applicants and licensees in preparing applications for new licenses, license amendments, and license renewals for the possession, use, and distribution of by-product material in nuclear pharmacy operations.

  3. 76 FR 20052 - Notice of Issuance of Regulatory Guide

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-11

    ... Guide 1.149, ``Nuclear Power Plant Simulation Facilities for Use in Operator Training, License..., ``Nuclear Power Plant Simulation Facilities for Use in Operator Training, License Examinations, and... simulation facility for use in operator and senior operator training, license examination operating tests...

  4. 75 FR 81675 - Notice of Issuance of Regulatory Guide

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-28

    ... Fuel Cycle Facilities.'' FOR FURTHER INFORMATION CONTACT: Mekonen M. Bayssie, Regulatory Guide... Materials in Liquid and Gaseous Effluents from Nuclear Fuel Cycle Facilities,'' was published as Draft... guidance is applicable to nuclear fuel cycle facilities, with the exception of uranium milling facilities...

  5. 76 FR 2725 - Draft Regulatory Guide: Issuance, Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-14

    .... The draft regulatory guide, entitled, ``Inspection of Water-Control Structures Associated with Nuclear... and surveillance program for dams, slopes, canals, and other water-control structures associated with emergency cooling water systems or flood protection of nuclear power plants. II. Further Information The NRC...

  6. Integrated Remote Sensing Modalities for Classification at a Legacy Test Site

    NASA Astrophysics Data System (ADS)

    Lee, D. J.; Anderson, D.; Craven, J.

    2016-12-01

    Detecting, locating, and characterizing suspected underground nuclear test sites is of interest to the worldwide nonproliferation monitoring community. Remote sensing provides both cultural and surface geological information over a large search area in a non-intrusive manner. We have characterized a legacy nuclear test site at the Nevada National Security Site (NNSS) using an aerial system based on RGB imagery, light detection and ranging, and hyperspectral imaging. We integrate these different remote sensing modalities to perform pattern recognition and classification tasks on the test site. These tasks include detecting cultural artifacts and exotic materials. We evaluate if the integration of different remote sensing modalities improves classification performance.

  7. Deep canyon and subalpine riparian and wetland plant associations of the Malheur, Umatilla, and Wallowa-Whitman National Forests.

    Treesearch

    Aaron F. Wells

    2006-01-01

    This guide presents a classification of the deep canyon and subalpine riparian and wetland vegetation types of the Malheur, Umatilla, and Wallowa-Whitman National Forests. A primary goal of the deep canyon and subalpine riparian and wetland classification was a seamless linkage with the midmontane northeastern Oregon riparian and wetland classification provided by...

  8. Author-Editor Guide to Technical Publications Preparation. Revision

    DTIC Science & Technology

    1990-01-01

    meteorology, climatology, military technical publications. ( ") <- 15: Number of Pages: 68 17. Security Classification of Report: Unclassified 1... Security Classification of this Page: Unclassified 19. Security Classification of Abstract: Unclassified 20. Limitation of Abstract: UL Standard Form 298...34 There are, however, February 1983. numerous exceptions. Although some technical material may not be classified in accordance with security AFR 83-2, Air

  9. EPRI Guide to Managing Nuclear Utility Protective Clothing Programs. PCEVAL User`s Manual, A computer code for evaluating the economics of nuclear plant protective clothing programs: Final report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kelly, J.J.; Kelly, D.M.

    1993-10-01

    The Electric Power Research Institute (EPRI) commissioned a radioactive waste related project (RP2414-34) in 1989 to produce a guide for developing and managing nuclear plant protective clothing programs. Every nuclear facility must coordinate some type of protective clothing program for its radiation workers to ensure proper and safe protection for the wearer and to maintain control over the spread of contamination. Yet, every nuclear facility has developed its own unique program for managing such clothing. Accordingly, a need existed for a reference guide to assist with standardizing protective clothing programs and in controlling the potentially escalating economics of such programs.more » The initial Guide to Managing Nuclear Utility Protective Clothing Programs, NP-7309, was published in May 1991. Since that time, a number of utilities have reviewed and/or used the report to enhance their protective clothing programs. Some of these utilities requested that a computer program be developed to assist utilities in evaluating the economics of protective clothing programs consistent with the guidance in NP-7309. The PCEVAL computer code responds to that industry need. This report, the PCEVAL User`s Manual, provides detailed instruction on use of the software.« less

  10. TCP/IP Implementations and Vendors Guide,

    DTIC Science & Technology

    1986-02-01

    DOCUMENTATION PAGE la. REPORT SECURITY CLASSIFICATION lb. RESTRICTIVE MARKINGS 2a. SECURITY CLASSIFICATION AUTHORITY 3. DISTRIBUTION/ AVAILABILIT OF...UNIX System V (5.2) IMPLEMENTATION-LANGUAGE: C DISTRIBUTOR: UNIQ Digital Technologies 28 S. Water St. Batavia, fI1 60510 (312) 879-1008 CONTACT

  11. 6 CFR 7.28 - Automatic declassification.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... years after the date of its original classification with the exception of specific information exempt... information whenever the information exempted does not identify a confidential human source or human... Classification Appeals Panel (ISCAP) for approval. (d) Declassification guides that narrowly and precisely define...

  12. 6 CFR 7.28 - Automatic declassification.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... years after the date of its original classification with the exception of specific information exempt... information whenever the information exempted does not identify a confidential human source or human... Classification Appeals Panel (ISCAP) for approval. (d) Declassification guides that narrowly and precisely define...

  13. 6 CFR 7.28 - Automatic declassification.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... years after the date of its original classification with the exception of specific information exempt... information whenever the information exempted does not identify a confidential human source or human... Classification Appeals Panel (ISCAP) for approval. (d) Declassification guides that narrowly and precisely define...

  14. 6 CFR 7.28 - Automatic declassification.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... years after the date of its original classification with the exception of specific information exempt... information whenever the information exempted does not identify a confidential human source or human... Classification Appeals Panel (ISCAP) for approval. (d) Declassification guides that narrowly and precisely define...

  15. Nuclear routing networks span between nuclear pore complexes and genomic DNA to guide nucleoplasmic trafficking of biomolecules

    PubMed Central

    Malecki, Marek; Malecki, Bianca

    2012-01-01

    In health and disease, biomolecules, which are involved in gene expression, recombination, or reprogramming have to traffic through the nucleoplasm, between nuclear pore complexes (NPCs) and genomic DNA (gDNA). This trafficking is guided by the recently revealed nuclear routing networks (NRNs). In this study, we aimed to investigate, if the NRNs have established associations with the genomic DNA in situ and if the NRNs have capabilities to bind the DNA de novo. Moreover, we aimed to study further, if nucleoplasmic trafficking of the histones, rRNA, and transgenes’ vectors, between the NPCs and gDNA, is guided by the NRNs. We used Xenopus laevis oocytes as the model system. We engineered the transgenes’ DNA vectors equipped with the SV40 LTA nuclear localization signals (NLS) and/or HIV Rev nuclear export signals (NES). We purified histones, 5S rRNA, and gDNA. We rendered all these molecules superparamagnetic and fluorescent for detection with nuclear magnetic resonance (NMR), total reflection x-ray fluorescence (TXRF), energy dispersive x-ray spectroscopy (EDXS), and electron energy loss spectroscopy (EELS). The NRNs span between the NPCs and genomic DNA. They form firm bonds with the gDNA in situ. After complete digestion of the nucleic acids with the RNases and DNases, the newly added DNA - modified with the dNTP analogs, bonds firmly to the NRNs. Moreover, the NRNs guide the trafficking of the DNA transgenes’ vectors - modified with the SV40 LTA NLS, following their import into the nuclei through the NPCs. The pathway is identical to that of histones. The NRNs also guide the trafficking of the DNA transgenes’ vectors, modified with the HIV Rev NES, to the NPCs, followed by their export out of the nuclei. Ribosomal RNAs follow the same pathway. To summarize, the NRNs are the structures connecting the NPCs and the gDNA. They guide the trafficking of the biomolecules between the NPCs and the gDNA. PMID:23275893

  16. 75 FR 45171 - Notice of Issuance of Regulatory Guide

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-02

    ... Engineering, Office of Nuclear Regulatory Research, U.S. Nuclear Regulatory Commission, Washington, DC 20555...-3040. This guide describes some engineering practices and methods generally considered by the NRC to be... they reflect the latest general engineering approaches that are acceptable to the NRC staff. If future...

  17. 77 FR 48177 - Fuel Oil Systems for Emergency Power Supplies

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-13

    ... NUCLEAR REGULATORY COMMISSION [NRC-2012-0159] Fuel Oil Systems for Emergency Power Supplies AGENCY: Nuclear Regulatory Commission. ACTION: Draft regulatory guide; extension of comment period. SUMMARY: On... Regulatory Guide, DG- 1282, ``Fuel Oil Systems for Emergency Power Supplies,'' in the Federal Register for a...

  18. The nuclear present. A guide to recent books on nuclear war, weapons, the peace movement, and related issues, with a chronology of nuclear events, 1789-1991

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Burns, G.

    The Nuclear Present brings the interested reader up-to-date on significant English-language books about nuclear weapons and related topics, identifying primarily important works of nuclear non-fiction that have come out since 1984. Each reference has a paragraph of comment about its subject and value. General organizational areas include the following: Reference Works; Nuclear weapons and Nuclear war (14 sub-headings including overviews, development, effects, tests, arms race, prospectives, legal considerations etc.); Strategy; proliferation; Stratigic Defense; Arms control and disarmament; ethical, pholosophical and religous perspectives; new paths to peace; periodic guide; the Chernobyl Disaster. An extensive Nuclear Chronology (1789-1991) written by the authormore » allows a fairly detailed sense of the historical record of nuclear weapons, including testing, manufacture, use and movements for arms control and disarmament.« less

  19. Plant Science. Instructor Guide [and] Student Reference. Volume 24, Numbers 3 and 4.

    ERIC Educational Resources Information Center

    Humphrey, John Kevin

    This document consists of two separately published guides for a course on plant science: an instructor's guide and a student's reference manual. Each part consists of eight lessons and cover the following topics: (1) importance of plants; (2) classification of plants; (3) plant growth factors; (4) weeds, diseases, insects; (5) germination; (6)…

  20. 17 CFR 200.507 - Declassification dates on derivative documents.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... derivative documents. 200.507 Section 200.507 Commodity and Securities Exchanges SECURITIES AND EXCHANGE... of National Security Information and Material § 200.507 Declassification dates on derivative... derivative document that derives its classification from the approved use of the classification guide of...

  1. A Characteristics-Based Approach to Radioactive Waste Classification in Advanced Nuclear Fuel Cycles

    NASA Astrophysics Data System (ADS)

    Djokic, Denia

    The radioactive waste classification system currently used in the United States primarily relies on a source-based framework. This has lead to numerous issues, such as wastes that are not categorized by their intrinsic risk, or wastes that do not fall under a category within the framework and therefore are without a legal imperative for responsible management. Furthermore, in the possible case that advanced fuel cycles were to be deployed in the United States, the shortcomings of the source-based classification system would be exacerbated: advanced fuel cycles implement processes such as the separation of used nuclear fuel, which introduce new waste streams of varying characteristics. To be able to manage and dispose of these potential new wastes properly, development of a classification system that would assign appropriate level of management to each type of waste based on its physical properties is imperative. This dissertation explores how characteristics from wastes generated from potential future nuclear fuel cycles could be coupled with a characteristics-based classification framework. A static mass flow model developed under the Department of Energy's Fuel Cycle Research & Development program, called the Fuel-cycle Integration and Tradeoffs (FIT) model, was used to calculate the composition of waste streams resulting from different nuclear fuel cycle choices: two modified open fuel cycle cases (recycle in MOX reactor) and two different continuous-recycle fast reactor recycle cases (oxide and metal fuel fast reactors). This analysis focuses on the impact of waste heat load on waste classification practices, although future work could involve coupling waste heat load with metrics of radiotoxicity and longevity. The value of separation of heat-generating fission products and actinides in different fuel cycles and how it could inform long- and short-term disposal management is discussed. It is shown that the benefits of reducing the short-term fission-product heat load of waste destined for geologic disposal are neglected under the current source-based radioactive waste classification system, and that it is useful to classify waste streams based on how favorable the impact of interim storage is on increasing repository capacity. The need for a more diverse set of waste classes is discussed, and it is shown that the characteristics-based IAEA classification guidelines could accommodate wastes created from advanced fuel cycles more comprehensively than the U.S. classification framework.

  2. 77 FR 64564 - Implementation of Regulatory Guide 1.221 on Design-Basis Hurricane and Hurricane Missiles

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-22

    ...-Basis Hurricane and Hurricane Missiles AGENCY: Nuclear Regulatory Commission. ACTION: Proposed interim...-ISG-024, ``Implementation of Regulatory Guide 1.221 on Design-Basis Hurricane and Hurricane Missiles....221, ``Design-Basis Hurricane and Hurricane Missiles for Nuclear Power Plants.'' DATES: Submit...

  3. 76 FR 82323 - Design, Inspection, and Testing Criteria for Air Filtration and Adsorption Units

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-30

    ... NUCLEAR REGULATORY COMMISSION [NRC-2011-0296] Design, Inspection, and Testing Criteria for Air... for public comment draft regulatory guide (DG), DG-1274, ``Design, Inspection, and Testing Criteria... Systems in Light-Water-Cooled Nuclear Power Plants.'' This guide applies to the design, inspection, and...

  4. 78 FR 36278 - Fuel Oil Systems for Emergency Power Supplies

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-17

    ... this notice (if that document is available in ADAMS) is provided the first time that a document is..., Office of Nuclear Regulatory Research, U.S. Nuclear Regulatory Commission, Washington, DC 20555-0001... issuing a revision to an existing guide in the NRC's ``Regulatory Guide'' series. This series was...

  5. Classification, disease, and diagnosis.

    PubMed

    Jutel, Annemarie

    2011-01-01

    Classification shapes medicine and guides its practice. Understanding classification must be part of the quest to better understand the social context and implications of diagnosis. Classifications are part of the human work that provides a foundation for the recognition and study of illness: deciding how the vast expanse of nature can be partitioned into meaningful chunks, stabilizing and structuring what is otherwise disordered. This article explores the aims of classification, their embodiment in medical diagnosis, and the historical traditions of medical classification. It provides a brief overview of the aims and principles of classification and their relevance to contemporary medicine. It also demonstrates how classifications operate as social framing devices that enable and disable communication, assert and refute authority, and are important items for sociological study.

  6. CRISPR-Cas9 nuclear dynamics and target recognition in living cells

    PubMed Central

    Ma, Hanhui; Tu, Li-Chun; Zhang, Shaojie; Grunwald, David

    2016-01-01

    The bacterial CRISPR-Cas9 system has been repurposed for genome engineering, transcription modulation, and chromosome imaging in eukaryotic cells. However, the nuclear dynamics of clustered regularly interspaced short palindromic repeats (CRISPR)–associated protein 9 (Cas9) guide RNAs and target interrogation are not well defined in living cells. Here, we deployed a dual-color CRISPR system to directly measure the stability of both Cas9 and guide RNA. We found that Cas9 is essential for guide RNA stability and that the nuclear Cas9–guide RNA complex levels limit the targeting efficiency. Fluorescence recovery after photobleaching measurements revealed that single mismatches in the guide RNA seed sequence reduce the target residence time from >3 h to as low as <2 min in a nucleotide identity- and position-dependent manner. We further show that the duration of target residence correlates with cleavage activity. These results reveal that CRISPR discriminates between genuine versus mismatched targets for genome editing via radical alterations in residence time. PMID:27551060

  7. Effect of Quantitative Nuclear Image Features on Recurrence of Ductal Carcinoma In Situ (DCIS) of the Breast

    PubMed Central

    Axelrod, David E.; Miller, Naomi A.; Lickley, H. Lavina; Qian, Jin; Christens-Barry, William A.; Yuan, Yan; Fu, Yuejiao; Chapman, Judith-Anne W.

    2008-01-01

    Background Nuclear grade has been associated with breast DCIS recurrence and progression to invasive carcinoma; however, our previous study of a cohort of patients with breast DCIS did not find such an association with outcome. Fifty percent of patients had heterogeneous DCIS with more than one nuclear grade. The aim of the current study was to investigate the effect of quantitative nuclear features assessed with digital image analysis on ipsilateral DCIS recurrence. Methods Hematoxylin and eosin stained slides for a cohort of 80 patients with primary breast DCIS were reviewed and two fields with representative grade (or grades) were identified by a Pathologist and simultaneously used for acquisition of digital images for each field. Van Nuys worst nuclear grade was assigned, as was predominant grade, and heterogeneous grading when present. Patients were grouped by heterogeneity of their nuclear grade: Group A: nuclear grade 1 only, nuclear grades 1 and 2, or nuclear grade 2 only (32 patients), Group B: nuclear grades 1, 2 and 3, or nuclear grades 2 and 3 (31 patients), Group 3: nuclear grade 3 only (17 patients). Nuclear fine structure was assessed by software which captured thirty-nine nuclear feature values describing nuclear morphometry, densitometry, and texture. Step-wise forward Cox regressions were performed with previous clinical and pathologic factors, and the new image analysis features. Results Duplicate measurements were similar for 89.7% to 97.4% of assessed image features. The rate of correct classification of nuclear grading with digital image analysis features was similar in the two fields, and pooled assessment across both fields. In the pooled assessment, a discriminant function with one nuclear morphometric and one texture feature was significantly (p = 0.001) associated with nuclear grading, and provided correct jackknifed classification of a patient’s nuclear grade for Group A (78.1%), Group B (48.4%), and Group C (70.6%). The factors significantly associated with DCIS recurrence were those previously found, type of initial presentation (p = 0.03) and amount of parenchymal involvement (p = 0.05), along with the morphometry image feature of ellipticity (p = 0.04). Conclusion Analysis of nuclear features measured by image cytometry may contribute to the classification and prognosis of breast DCIS patients with more than one nuclear grade. PMID:18779878

  8. 76 FR 50274 - Terrestrial Environmental Studies for Nuclear Power Stations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-12

    ... NUCLEAR REGULATORY COMMISSION [NRC-2011-0182] Terrestrial Environmental Studies for Nuclear Power... draft regulatory guide (DG), DG-4016, ``Terrestrial Environmental Studies for Nuclear Power Stations... environmental studies and analyses supporting licensing decisions for nuclear power reactors. DATES: Submit...

  9. Integration of adaptive guided filtering, deep feature learning, and edge-detection techniques for hyperspectral image classification

    NASA Astrophysics Data System (ADS)

    Wan, Xiaoqing; Zhao, Chunhui; Gao, Bing

    2017-11-01

    The integration of an edge-preserving filtering technique in the classification of a hyperspectral image (HSI) has been proven effective in enhancing classification performance. This paper proposes an ensemble strategy for HSI classification using an edge-preserving filter along with a deep learning model and edge detection. First, an adaptive guided filter is applied to the original HSI to reduce the noise in degraded images and to extract powerful spectral-spatial features. Second, the extracted features are fed as input to a stacked sparse autoencoder to adaptively exploit more invariant and deep feature representations; then, a random forest classifier is applied to fine-tune the entire pretrained network and determine the classification output. Third, a Prewitt compass operator is further performed on the HSI to extract the edges of the first principal component after dimension reduction. Moreover, the regional growth rule is applied to the resulting edge logical image to determine the local region for each unlabeled pixel. Finally, the categories of the corresponding neighborhood samples are determined in the original classification map; then, the major voting mechanism is implemented to generate the final output. Extensive experiments proved that the proposed method achieves competitive performance compared with several traditional approaches.

  10. User Education Resources: USER.

    ERIC Educational Resources Information Center

    Condon, Patrick; Cook, Johanna

    This report describes User Education Resources (USER), an Australian database containing both print and audiovisual materials related to library instruction. Intended to make a wide range of ideas readily available to librarians interested in educating library patrons, USER collects catalog guides, classification guides, evaluation forms, floor…

  11. Short Course in Highway Lighting.

    ERIC Educational Resources Information Center

    Federal Highway Administration (DOT), Washington, DC.

    This course guide in highway lighting includes an overview of trends in highway lighting, illustrated information on three light sources for today's luminaires, a reference guide to lamp classification, specifications for highway lighting equipment, and instructions for calculating appropriate use. Maintenance notes on highway illumination and…

  12. A novel method to guide classification of para swimmers with limb deficiency.

    PubMed

    Hogarth, Luke; Payton, Carl; Van de Vliet, Peter; Connick, Mark; Burkett, Brendan

    2018-05-30

    The International Paralympic Committee has directed International Federations that govern Para sports to develop evidence-based classification systems. This study defined the impact of limb deficiency impairment on 100 m freestyle performance to guide an evidence-based classification system in Para Swimming, which will be implemented following the 2020 Tokyo Paralympic games. Impairment data and competitive race performances of 90 international swimmers with limb deficiency were collected. Ensemble partial least squares regression established the relationship between relative limb length measures and competitive 100 m freestyle performance. The model explained 80% of the variance in 100 m freestyle performance, and found hand length and forearm length to be the most important predictors of performance. Based on the results of this model, Para swimmers were clustered into four-, five-, six- and seven-class structures using nonparametric kernel density estimations. The validity of these classification structures, and effectiveness against the current classification system, were examined by establishing within-class variations in 100 m freestyle performance and differences between adjacent classes. The derived classification structures were found to be more effective than current classification based on these criteria. This study provides a novel method that can be used to improve the objectivity and transparency of decision-making in Para sport classification. Expert consensus from experienced coaches, Para swimmers, classifiers and sport science and medicine personnel will benefit the translation of these findings into a revised classification system that is accepted by the Para swimming community. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

  13. 78 FR 64028 - Decommissioning of Nuclear Power Reactors

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-25

    ... NUCLEAR REGULATORY COMMISSION [NRC-2012-0035] Decommissioning of Nuclear Power Reactors AGENCY... Commission (NRC) is issuing Revision 1 of regulatory guide (RG) 1.184 ``Decommissioning of Nuclear Power... the NRC's regulations relating to the decommissioning process for nuclear power reactors. The revision...

  14. 76 FR 65541 - Assuring the Availability of Funds for Decommissioning Nuclear Reactors

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-21

    ... NUCLEAR REGULATORY COMMISSION [NRC-2009-0263] Assuring the Availability of Funds for Decommissioning Nuclear Reactors AGENCY: Nuclear Regulatory Commission. ACTION: Regulatory guide; issuance. SUMMARY: The U.S. Nuclear Regulatory Commission (NRC or Commission) is issuing a revision to Regulatory...

  15. Method for automatically scramming a nuclear reactor

    DOEpatents

    Ougouag, Abderrafi M.; Schultz, Richard R.; Terry, William K.

    2005-12-27

    An automatically scramming nuclear reactor system. One embodiment comprises a core having a coolant inlet end and a coolant outlet end. A cooling system operatively associated with the core provides coolant to the coolant inlet end and removes heated coolant from the coolant outlet end, thus maintaining a pressure differential therebetween during a normal operating condition of the nuclear reactor system. A guide tube is positioned within the core with a first end of the guide tube in fluid communication with the coolant inlet end of the core, and a second end of the guide tube in fluid communication with the coolant outlet end of the core. A control element is positioned within the guide tube and is movable therein between upper and lower positions, and automatically falls under the action of gravity to the lower position when the pressure differential drops below a safe pressure differential.

  16. [Value of a novel categorization of congenital double-outlet right ventricle on guiding the choice of surgical approaches].

    PubMed

    Pang, Kunjing; Meng, Hong; Wang, Hao; Hu, Shengshou; Hua, Zhongdong; Pan, Xiangbin; Li, Shoujun

    2015-11-01

    To explore the feasibility and value of a new categorization of double outlet right ventricular (DORV) on guiding the optimal choices of surgical approaches. Five hundred and twenty one DORV patients diagnosed by echocardiography, angiocardiography and CT at Fuwai Hospital from May 2003 to September 2014 were enrolled in this retrospective study. Congenital DORV was categorized according to three basic factors as follows: the positional relationships of great arteries (normal relation or abnormal relation), the relationships of the ventricular septal defect (VSD) to the great arteries (committed VSD or remote VSD), the presence or absence of pulmonary outflow tract obstruction (POTO). Eight types of DORV were established: type I (normal relation, committed VSD, without POTO), type II (normal relation, committed VSD, POTO), type III (normal relation, remote VSD, without POTO), type IV (normal relation, remote VSD, POTO), type V (abnormal relation, committed VSD, without POTO), type VI (abnormal relation, committed VSD, POTO), type VII (abnormal relation, remote VSD, without POTO), type VIII (abnormal relation, remote VSD, POTO). Feasibility of this classification and the value of this classification on guiding the choice of surgical approaches were analyzed. Among the five hundred and twenty one patients, there were 90 patients (17.3%) with type I DORV, 94 patients (18.0%) with type II, 33 patients (6.3%) with type III, 34 patients (6.5%) with type IV, 64 patients (12.3%) with type V, 61 patients (11.7%) with type VI, 33 patients (6.3%) with type VII, 112 patients (21.5%) with type VIII. Thus, all patients could be typed by this classification method. The echocardiography diagnosis was consistent with the intra-operative and or cardiac catheterization/CT findings. Excluding the contraindications of bi-ventricular repair, different surgical approaches were performed in every subtype of DORV according the classification, which indicated that this novel categorization could accurately guide the clinic managements. This novel DORV categorization can accurately diagnose DORV lesions, and guide the clinic therapy choice.

  17. Osteochondritis dissecans of the humeral capitellum: reliability of four classification systems using radiographs and computed tomography.

    PubMed

    Claessen, Femke M A P; van den Ende, Kimberly I M; Doornberg, Job N; Guitton, Thierry G; Eygendaal, Denise; van den Bekerom, Michel P J

    2015-10-01

    The radiographic appearance of osteochondritis dissecans (OCD) of the humeral capitellum varies according to the stage of the lesion. It is important to evaluate the stage of OCD lesion carefully to guide treatment. We compared the interobserver reliability of currently used classification systems for OCD of the humeral capitellum to identify the most reliable classification system. Thirty-two musculoskeletal radiologists and orthopaedic surgeons specialized in elbow surgery from several countries evaluated anteroposterior and lateral radiographs and corresponding computed tomography (CT) scans of 22 patients to classify the stage of OCD of the humeral capitellum according to the classification systems developed by (1) Minami, (2) Berndt and Harty, (3) Ferkel and Sgaglione, and (4) Anderson on a Web-based study platform including a Digital Imaging and Communications in Medicine viewer. Magnetic resonance imaging was not evaluated as part of this study. We measured agreement among observers using the Siegel and Castellan multirater κ. All OCD classification systems, except for Berndt and Harty, which had poor agreement among observers (κ = 0.20), had fair interobserver agreement: κ was 0.27 for the Minami, 0.23 for Anderson, and 0.22 for Ferkel and Sgaglione classifications. The Minami Classification was significantly more reliable than the other classifications (P < .001). The Minami Classification was the most reliable for classifying different stages of OCD of the humeral capitellum. However, it is unclear whether radiographic evidence of OCD of the humeral capitellum, as categorized by the Minami Classification, guides treatment in clinical practice as a result of this fair agreement. Copyright © 2015 Journal of Shoulder and Elbow Surgery Board of Trustees. Published by Elsevier Inc. All rights reserved.

  18. A Global Covariance Descriptor for Nuclear Atypia Scoring in Breast Histopathology Images.

    PubMed

    Khan, Adnan Mujahid; Sirinukunwattana, Korsuk; Rajpoot, Nasir

    2015-09-01

    Nuclear atypia scoring is a diagnostic measure commonly used to assess tumor grade of various cancers, including breast cancer. It provides a quantitative measure of deviation in visual appearance of cell nuclei from those in normal epithelial cells. In this paper, we present a novel image-level descriptor for nuclear atypia scoring in breast cancer histopathology images. The method is based on the region covariance descriptor that has recently become a popular method in various computer vision applications. The descriptor in its original form is not suitable for classification of histopathology images as cancerous histopathology images tend to possess diversely heterogeneous regions in a single field of view. Our proposed image-level descriptor, which we term as the geodesic mean of region covariance descriptors, possesses all the attractive properties of covariance descriptors lending itself to tractable geodesic-distance-based k-nearest neighbor classification using efficient kernels. The experimental results suggest that the proposed image descriptor yields high classification accuracy compared to a variety of widely used image-level descriptors.

  19. Influence of nuclei segmentation on breast cancer malignancy classification

    NASA Astrophysics Data System (ADS)

    Jelen, Lukasz; Fevens, Thomas; Krzyzak, Adam

    2009-02-01

    Breast Cancer is one of the most deadly cancers affecting middle-aged women. Accurate diagnosis and prognosis are crucial to reduce the high death rate. Nowadays there are numerous diagnostic tools for breast cancer diagnosis. In this paper we discuss a role of nuclear segmentation from fine needle aspiration biopsy (FNA) slides and its influence on malignancy classification. Classification of malignancy plays a very important role during the diagnosis process of breast cancer. Out of all cancer diagnostic tools, FNA slides provide the most valuable information about the cancer malignancy grade which helps to choose an appropriate treatment. This process involves assessing numerous nuclear features and therefore precise segmentation of nuclei is very important. In this work we compare three powerful segmentation approaches and test their impact on the classification of breast cancer malignancy. The studied approaches involve level set segmentation, fuzzy c-means segmentation and textural segmentation based on co-occurrence matrix. Segmented nuclei were used to extract nuclear features for malignancy classification. For classification purposes four different classifiers were trained and tested with previously extracted features. The compared classifiers are Multilayer Perceptron (MLP), Self-Organizing Maps (SOM), Principal Component-based Neural Network (PCA) and Support Vector Machines (SVM). The presented results show that level set segmentation yields the best results over the three compared approaches and leads to a good feature extraction with a lowest average error rate of 6.51% over four different classifiers. The best performance was recorded for multilayer perceptron with an error rate of 3.07% using fuzzy c-means segmentation.

  20. Hyperspectral recognition of processing tomato early blight based on GA and SVM

    NASA Astrophysics Data System (ADS)

    Yin, Xiaojun; Zhao, SiFeng

    2013-03-01

    Processing tomato early blight seriously affect the yield and quality of its.Determine the leaves spectrum of different disease severity level of processing tomato early blight.We take the sensitive bands of processing tomato early blight as support vector machine input vector.Through the genetic algorithm(GA) to optimize the parameters of SVM, We could recognize different disease severity level of processing tomato early blight.The result show:the sensitive bands of different disease severity levels of processing tomato early blight is 628-643nm and 689-692nm.The sensitive bands are as the GA and SVM input vector.We get the best penalty parameters is 0.129 and kernel function parameters is 3.479.We make classification training and testing by polynomial nuclear,radial basis function nuclear,Sigmoid nuclear.The best classification model is the radial basis function nuclear of SVM. Training accuracy is 84.615%,Testing accuracy is 80.681%.It is combined GA and SVM to achieve multi-classification of processing tomato early blight.It is provided the technical support of prediction processing tomato early blight occurrence, development and diffusion rule in large areas.

  1. 77 FR 60481 - Design, Inspection, and Testing Criteria for Air Filtration and Adsorption Units of Post-Accident...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-03

    ...The U.S. Nuclear Regulatory Commission (NRC or the Commission) is issuing a revision to Regulatory Guide (RG) 1.52, ``Design, Inspection, and Testing Criteria for Air Filtration and Adsorption Units of Post-accident Engineered-Safety-Feature Atmosphere Cleanup Systems in Light-Water-Cooled Nuclear Power Plants.'' This guide applies to the design, inspection, and testing of air filtration and iodine adsorption units of engineered-safety-feature (ESF) atmosphere cleanup systems in light-water-cooled nuclear power plants.

  2. 76 FR 66089 - Access Authorization Program for Nuclear Power Plants

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-25

    ... NUCLEAR REGULATORY COMMISSION [NRC-2011-0245] Access Authorization Program for Nuclear Power... Program for Nuclear Power Plants.'' This guide describes a method that NRC staff considers acceptable to... Regulations (10 CFR), section 73.56, ``Personnel Access Authorization Requirements for Nuclear Power Plants...

  3. Elementary Science Resource Guide.

    ERIC Educational Resources Information Center

    Texas Education Agency, Austin. Div. of Curriculum Development.

    This guide for elementary teachers provides information on getting ideas into action, designing and implementing the right situation, ways in which to evaluate science process activities with students, and seven sample units. The units cover using the senses, magnets, forces, weather forecasting, classification of living things, and the physical…

  4. 10 CFR 95.37 - Classification and preparation of documents.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Information must contain the identity of the source document or the classification guide, including the agency.../Exemption) Classifier: (Name/Title/Number) (2) For Restricted Data documents: (i) Identity of the classifier. The identity of the classifier must be shown by completion of the “Derivative Classifier” line. The...

  5. 10 CFR 95.37 - Classification and preparation of documents.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Information must contain the identity of the source document or the classification guide, including the agency.../Exemption) Classifier: (Name/Title/Number) (2) For Restricted Data documents: (i) Identity of the classifier. The identity of the classifier must be shown by completion of the “Derivative Classifier” line. The...

  6. 10 CFR 95.37 - Classification and preparation of documents.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Information must contain the identity of the source document or the classification guide, including the agency.../Exemption) Classifier: (Name/Title/Number) (2) For Restricted Data documents: (i) Identity of the classifier. The identity of the classifier must be shown by completion of the “Derivative Classifier” line. The...

  7. Technetium-99m: basic nuclear physics and chemical properties.

    PubMed

    Castronovo, F P

    1975-05-01

    The nuclear physics and chemical properties of technetium-99m are reviewed. The review of basic nuclear physics includes: classification of nuclides, nuclear stability, production of radionuclides, artificial production of molybdenum-99, production of technetium 99m and -99Mo-99mTc generators. The discussion of the chemistry of technetium includes a profile of several -99mCc-labeled radiopharmaceuticals.

  8. Confinement of Radioactive Materials at Defense Nuclear Facilities

    DTIC Science & Technology

    2004-10-01

    The design of defense nuclear facilities includes systems whose reliable operation is vital to the protection of the public, workers, and the...final safety-class barrier to the release of hazardous materials with potentially serious public consequences. The Defense Nuclear Facilities Safety...the public at certain defense nuclear facilities . This change has resulted in downgrading of the functional safety classification of confinement

  9. Gyrotropic Guiding-Center Fluid Theory for Turbulent Inhomogeneous Magnetized Plasma

    DTIC Science & Technology

    2006-01-01

    this paper, a new fluid theory is given in the guiding-center and gyrotropic approximation which is derivable from the Vlasov-Maxwell equations . The... equations can be solved (1) by using measurements of the low-order velocity moments to specify the initial and boundary conditions. 15. SUBJECT TERMS...Vlasov-Maxwell equations Fokker-Planck operator guiding-center Inhomogeneous, gyrotropic, magnetized plasma 16. SECURITY CLASSIFICATION OF: 17

  10. 78 FR 15753 - Maintenance, Testing, and Replacement of Vented Lead-Acid Storage Batteries for Nuclear Power Plants

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-12

    .... Although a time limit is given, comments and suggestions in connection with items for inclusion in guides currently being developed or improvements in all published guides are encouraged at any time. ADDRESSES: You...: 301-251-7455, or by email: [email protected] . Both of the Office of Nuclear Regulatory Research...

  11. 77 FR 18271 - Terrestrial Environmental Studies for Nuclear Power Stations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-27

    ... NUCLEAR REGULATORY COMMISSION [NRC-2011-0182] Terrestrial Environmental Studies for Nuclear Power... Environmental Studies for Nuclear Power Stations.'' This guide provides technical guidance that the NRC staff... nuclear power reactors. ADDRESSES: Please refer to Docket ID NRC-2011-0182 when contacting the NRC about...

  12. Residential Wiring. Second Edition.

    ERIC Educational Resources Information Center

    Taylor, Mark; And Others

    This guide is designed to assist teachers conducting a course to prepare students for entry-level employment in the residential wiring trade. Included in the guide are six instructional units and the following sections of information for teachers: guidelines in using the unit components; academic and workplace skills classifications and…

  13. 10 CFR 1045.2 - Applicability.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Applicability. 1045.2 Section 1045.2 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) NUCLEAR CLASSIFICATION AND DECLASSIFICATION Program Management of the Restricted Data and Formerly Restricted Data Classification System § 1045.2 Applicability. This subpart...

  14. 10 CFR 1045.1 - Purpose and scope.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... OF ENERGY (GENERAL PROVISIONS) NUCLEAR CLASSIFICATION AND DECLASSIFICATION Program Management of the Restricted Data and Formerly Restricted Data Classification System § 1045.1 Purpose and scope. This subpart establishes responsibilities associated with this part, describes the Openness Advisory Panel, defines key...

  15. 10 CFR 1045.1 - Purpose and scope.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... OF ENERGY (GENERAL PROVISIONS) NUCLEAR CLASSIFICATION AND DECLASSIFICATION Program Management of the Restricted Data and Formerly Restricted Data Classification System § 1045.1 Purpose and scope. This subpart establishes responsibilities associated with this part, describes the Openness Advisory Panel, defines key...

  16. 78 FR 25488 - Qualification Tests for Safety-Related Actuators in Nuclear Power Plants

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-01

    ... NUCLEAR REGULATORY COMMISSION [NRC-2013-0079] Qualification Tests for Safety-Related Actuators in... regulatory guide (DG), DG-1235, ``Qualification Tests for Safety-Related Actuators in Nuclear Power Plants...-251- 7495, email: [email protected] . Both of the Office of Nuclear Regulatory Research, U.S. Nuclear...

  17. 76 FR 82201 - General Site Suitability Criteria for Nuclear Power Stations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-30

    ..., and 52 [NRC-2011-0297] General Site Suitability Criteria for Nuclear Power Stations AGENCY: Nuclear... Suitability Criteria for Nuclear Power Stations.'' This guide describes a method that the NRC staff considers acceptable to implement the site suitability requirements for nuclear power stations. DATES: Submit comments...

  18. 76 FR 74630 - Making Changes to Emergency Plans for Nuclear Power Reactors

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-01

    ... NUCLEAR REGULATORY COMMISSION 10 CFR Parts 50 and 52 RIN 3150-AI10 [NRC-2008-0122] Making Changes to Emergency Plans for Nuclear Power Reactors AGENCY: Nuclear Regulatory Commission. ACTION... guide (RG) 1.219, ``Guidance on Making Changes to Emergency Plans for Nuclear Power Reactors.'' This...

  19. 78 FR 24438 - Evaluations of Explosions Postulated To Occur at Nearby Facilities and on Transportation Routes...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-25

    ... Nearby Facilities and on Transportation Routes Near Nuclear Power Plants AGENCY: Nuclear Regulatory... Nearby Facilities and on Transportation Routes Near Nuclear Power Plants.'' This regulatory guide describes for applicants seeking nuclear power reactor licenses and licensees of nuclear power reactors...

  20. 78 FR 73566 - Standard Format and Content for a License Application for an Independent Spent Fuel Storage...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-06

    ...The U.S. Nuclear Regulatory Commission (NRC) is issuing for public comment draft regulatory guide (DG), DG-3042, ``Standard Format and Content for a License Application for an Independent Spent Fuel Storage Installation or a Monitored Retrievable Storage Facility.'' This draft regulatory guide is proposed revision 2 of Regulatory Guide 3.50, which provides a format that the NRC considers acceptable for submitting the information for license applications to store spent nuclear fuel, high-level radioactive waste, and/or reactor-related Greater than Class C waste.

  1. Multi-Level Scenario Module 1: 7th Division

    DTIC Science & Technology

    2009-03-01

    MQ1B Recon Sq 1x RC135S Recon Sq 5x RC135VW Cythera Paros Shaw Peterson Fighter Sq 24x F16CD BLK-50 Fighter Sq 24x F15E Fighter Sq 24x A/0A10A Airlift Sq...Mountain Home Amphibious Assault Ship, Multipurpose (LHD) Amphibious Transport Dock (LPD) Dock Landing Ship ( LSD ) Guided Missile Cruiser (CG...Destroyer (DDG) x2 Submarine, Nuclear Powered (SSN) x 6 Guided Missile Submarine, Nuclear Powered (SSGN) Cythera Paros Shaw Peterson Guided

  2. Event-Related fMRI of Category Learning: Differences in Classification and Feedback Networks

    ERIC Educational Resources Information Center

    Little, Deborah M.; Shin, Silvia S.; Sisco, Shannon M.; Thulborn, Keith R.

    2006-01-01

    Eighteen healthy young adults underwent event-related (ER) functional magnetic resonance imaging (fMRI) of the brain while performing a visual category learning task. The specific category learning task required subjects to extract the rules that guide classification of quasi-random patterns of dots into categories. Following each classification…

  3. Vegetation classification system for California: user's guide

    Treesearch

    Serena C. Hunter; Timothy E. Paysen

    1986-01-01

    The Vegetation Classification System for California is an unbiased system of defining and naming units of vegetation. The concept was devised by an interagency, interdisciplinary team (Paysen and others 1980, 1982). The system derives its uniqueness from its impartiality to any particular agency or resource discipline, thus providing a long-needed link between diverse...

  4. Science, Society, and America's Nuclear Waste: Ionizing Radiation, Unit 2. Teacher Guide. Second Edition.

    ERIC Educational Resources Information Center

    Department of Energy, Washington, DC. Office of Civilian Radioactive Waste Management, Washington, DC.

    This guide is Unit 2 of the four-part series, Science, Society, and America's Nuclear Waste, produced by the U.S. Department of Energy's Office of Civilian Radioactive Waste Management. The goal of this unit is to convey factual information relevant to radioactivity and radiation and relate that information both to the personal lives of students…

  5. Study Guide for TCT in Science.

    ERIC Educational Resources Information Center

    Clark, Gene

    This study guide was developed for individuals preparing to take the Georgia Teacher Certification Test (TCT) in science. Content objectives of the test are listed and encompass: (1) scientific processes, research, and classification; (2) earth sciences; (3) characteristics and properties of matter, energy, and chemical change; (4) biology of life…

  6. Product Guide/1972 [Air Pollution Control Association].

    ERIC Educational Resources Information Center

    Journal of the Air Pollution Control Association, 1971

    1971-01-01

    Reprinted in this pamphlet is the fifth annual directory of air pollution control products as compiled in the "Journal of the Air Pollution Control Association" for December, 1971. The 16-page guide lists manufacturers of emission control equipment and air pollution instrumentation under product classifications as derived from McGraw-Hill's "Air…

  7. 10 CFR 1045.5 - Sanctions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Sanctions. 1045.5 Section 1045.5 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) NUCLEAR CLASSIFICATION AND DECLASSIFICATION Program Management of the Restricted Data and Formerly Restricted Data Classification System § 1045.5 Sanctions. (a) Knowing, willful...

  8. 10 CFR 1045.12 - Authorities.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Authorities. 1045.12 Section 1045.12 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) NUCLEAR CLASSIFICATION AND DECLASSIFICATION Identification of Restricted Data and Formerly Restricted Data Information § 1045.12 Authorities. (a) The Director of Classification may...

  9. TFM classification and staging of oral submucous fibrosis: A new proposal.

    PubMed

    Arakeri, Gururaj; Thomas, Deepak; Aljabab, Abdulsalam S; Hunasgi, Santosh; Rai, Kirthi Kumar; Hale, Beverley; Fonseca, Felipe Paiva; Gomez, Ricardo Santiago; Rahimi, Siavash; Merkx, Matthias A W; Brennan, Peter A

    2018-04-01

    We have evaluated the rationale of existing grading and staging schemes of oral submucous fibrosis (OSMF) based on how they are categorized. A novel classification and staging scheme is proposed. A total of 300 OSMF patients were evaluated for agreement between functional, clinical, and histopathological staging. Bilateral biopsies were assessed in 25 patients to evaluate for any differences in histopathological staging of OSMF in the same mouth. Extent of clinician agreement for categorized staging data was evaluated using Cohen's weighted kappa analysis. Cross-tabulation was performed on categorical grading data to understand the intercorrelation, and the unweighted kappa analysis was used to assess the bilateral grade agreement. Probabilities of less than 0.05 were considered significant. Data were analyzed using SPSS Statistics (version 25.0, IBM, USA). A low agreement was found between all the stages depicting the independent nature of trismus, clinical features, and histopathological components (K = 0.312, 0.167, 0.152) in OSMF. Following analysis, a three-component classification scheme (TFM classification) was developed that describes the severity of each independently, grouping them using a novel three-tier staging scheme as a guide to the treatment plan. The proposed classification and staging could be useful for effective communication, categorization, and for recording data and prognosis, and for guiding treatment plans. Furthermore, the classification considers OSMF malignant transformation in detail. © 2018 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  10. A guide to studying human hair follicle cycling in vivo

    PubMed Central

    Oh, Ji Won; Kloepper, Jennifer; Langan, Ewan A.; Kim, Yongsoo; Yeo, Joongyeub; Kim, Min Ji; Hsi, Tsai-Ching; Rose, Christian; Yoon, Ghil Suk; Lee, Seok-Jong; Seykora, John; Kim, Jung Chul; Sung, Young Kwan

    2015-01-01

    Hair follicles (HFs) undergo life-long cyclical transformations, progressing through stages of rapid growth (anagen), regression (catagen), and relative “quiescence” (telogen). Since HF cycling abnormalities underlie many human hair growth disorders, the accurate classification of individual cycle stages within skin biopsies is clinically important and essential for hair research. For preclinical human hair research purposes, human scalp skin can be xenografted onto immunocompromised mice to study human HF cycling and manipulate long-lasting anagen in vivo. While available for mice, a comprehensive guide on how to recognize different human hair cycle stages in vivo is lacking. Here, we present such a guide, which uses objective, well-defined, and reproducible criteria and integrates simple morphological indicators with advanced, (immuno)-histochemical markers. This guide also characterizes human HF cycling in xenografts and highlights the utility of this model for in vivo hair research. Detailed schematic drawings and representative micrographs provide examples of how best to identify human HF stages, even in sub-optimally sectioned tissue, and practical recommendations are given for designing human-on-mouse hair cycle experiments. Thus, this guide seeks to offer a benchmark for human hair cycle stage classification, for both hair research experts and newcomers to the field. PMID:26763421

  11. 77 FR 36017 - Regulatory Guide 7.3, Procedures for Picking Up and Receiving Packages of Radioactive Material

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-15

    ... Receiving Packages of Radioactive Material AGENCY: Nuclear Regulatory Commission. ACTION: Notice of... Guide (RG) 7.3, ``Procedures for Picking Up and Receiving Packages of Radioactive Material.'' The guide..., ``Administrative Guide for Verifying Compliance with Packaging Requirements for Shipment and Receipt of Radioactive...

  12. A multi-temporal fusion-based approach for land cover mapping in support of nuclear incident response

    NASA Astrophysics Data System (ADS)

    Sah, Shagan

    An increasingly important application of remote sensing is to provide decision support during emergency response and disaster management efforts. Land cover maps constitute one such useful application product during disaster events; if generated rapidly after any disaster, such map products can contribute to the efficacy of the response effort. In light of recent nuclear incidents, e.g., after the earthquake/tsunami in Japan (2011), our research focuses on constructing rapid and accurate land cover maps of the impacted area in case of an accidental nuclear release. The methodology involves integration of results from two different approaches, namely coarse spatial resolution multi-temporal and fine spatial resolution imagery, to increase classification accuracy. Although advanced methods have been developed for classification using high spatial or temporal resolution imagery, only a limited amount of work has been done on fusion of these two remote sensing approaches. The presented methodology thus involves integration of classification results from two different remote sensing modalities in order to improve classification accuracy. The data used included RapidEye and MODIS scenes over the Nine Mile Point Nuclear Power Station in Oswego (New York, USA). The first step in the process was the construction of land cover maps from freely available, high temporal resolution, low spatial resolution MODIS imagery using a time-series approach. We used the variability in the temporal signatures among different land cover classes for classification. The time series-specific features were defined by various physical properties of a pixel, such as variation in vegetation cover and water content over time. The pixels were classified into four land cover classes - forest, urban, water, and vegetation - using Euclidean and Mahalanobis distance metrics. On the other hand, a high spatial resolution commercial satellite, such as RapidEye, can be tasked to capture images over the affected area in the case of a nuclear event. This imagery served as a second source of data to augment results from the time series approach. The classifications from the two approaches were integrated using an a posteriori probability-based fusion approach. This was done by establishing a relationship between the classes, obtained after classification of the two data sources. Despite the coarse spatial resolution of MODIS pixels, acceptable accuracies were obtained using time series features. The overall accuracies using the fusion-based approach were in the neighborhood of 80%, when compared with GIS data sets from New York State. This fusion thus contributed to classification accuracy refinement, with a few additional advantages, such as correction for cloud cover and providing for an approach that is robust against point-in-time seasonal anomalies, due to the inclusion of multi-temporal data. We concluded that this approach is capable of generating land cover maps of acceptable accuracy and rapid turnaround, which in turn can yield reliable estimates of crop acreage of a region. The final algorithm is part of an automated software tool, which can be used by emergency response personnel to generate a nuclear ingestion pathway information product within a few hours of data collection.

  13. 77 FR 70846 - Regulatory Guide 1.182, “Assessing and Managing Risk Before Maintenance Activities at Nuclear...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-27

    ... Risk Before Maintenance Activities at Nuclear Power Plants'' AGENCY: Nuclear Regulatory Commission... Activities at Nuclear Power Plants,'' published in May 2000. The document is redundant due to the inclusion... Risk Before Maintenance Activities at Nuclear Power Plants,'' published in May 2000. The requirements...

  14. Revisiting the structure/function relationships of H/ACA(-like) RNAs: a unified model for Euryarchaea and Crenarchaea

    PubMed Central

    Toffano-Nioche, Claire; Gautheret, Daniel; Leclerc, Fabrice

    2015-01-01

    A structural and functional classification of H/ACA and H/ACA-like motifs is obtained from the analysis of the H/ACA guide RNAs which have been identified previously in the genomes of Euryarchaea (Pyrococcus) and Crenarchaea (Pyrobaculum). A unified structure/function model is proposed based on the common structural determinants shared by H/ACA and H/ACA-like motifs in both Euryarchaea and Crenarchaea. Using a computational approach, structural and energetic rules for the guide:target RNA-RNA interactions are derived from structural and functional data on the H/ACA RNP particles. H/ACA(-like) motifs found in Pyrococcus are evaluated through the classification and their biological relevance is discussed. Extra-ribosomal targets found in both Pyrococcus and Pyrobaculum might support the hypothesis of a gene regulation mediated by H/ACA(-like) guide RNAs in archaea. PMID:26240384

  15. Symptom classification in irritable bowel syndrome as a guide to treatment.

    PubMed

    Wiesner, Maureen; Naylor, Sally J; Copping, Ann; Furlong, Anita; Lynch, Andrew G; Parkes, Miles; Hunter, John O

    2009-01-01

    The treatment of irritable bowel syndrome (IBS) remains unsatisfactory. There are no objective markers for diagnosis, and classification (currently based on symptoms) provides little insight into potential causes or optimal therapy. The aim of this study was to determine whether a Swedish classification of IBS based on cluster analysis of patients' symptoms might provide a guide to successful treatment. Patients in a research clinic for IBS were classified according to criteria published by Ragnarsson & Bodemar (R&B) and also assessed independently by a clinician. Patients fulfilling the R&B criteria for subgroups 1 and 2 received specific treatments, either bulk laxatives or dietary treatment to reduce colonic fermentation, respectively. Patients who did not fit into these categories were given "best treatment" targeted at their predominant symptoms, but not limited in any way. Results before and after follow-up were assessed using a validated symptom-scoring scale. Seventy-one successive patients were recruited, and the numbers falling into R&B subgroups 1 and 2 were 15 (21%), and 28 (39%), respectively, leaving 28 (39%) unclassified. Receiver operating characteristic plots showed that the criteria for separation into subgroups 1 and 2 correlated well with the clinician's assessment. After treatment, symptom scores for the whole group showed a significant improvement (p<0.0001), but results were significantly better in subgroups 1 and 2 than in those unclassified, even when allowance was made for a potential therapeutic placebo effect of 40%. The R&B classification provides a helpful guide to treatment in many cases of IBS.

  16. Crisis Communications between Superpowers

    DTIC Science & Technology

    1990-02-12

    Comunications Between Superpowers FORMAT: Individual Study Project DATE: 12 February 1990 PAGES: 28 CLASSIFICATIONs Unclassified Ever since the United...have not. Increasing numbers of Third World countries have the potential to develop and use nuclear weapons. Nuclear terrorism could become a possibility

  17. Nuclear Power Plant Thermocouple Sensor-Fault Detection and Classification Using Deep Learning and Generalized Likelihood Ratio Test

    NASA Astrophysics Data System (ADS)

    Mandal, Shyamapada; Santhi, B.; Sridhar, S.; Vinolia, K.; Swaminathan, P.

    2017-06-01

    In this paper, an online fault detection and classification method is proposed for thermocouples used in nuclear power plants. In the proposed method, the fault data are detected by the classification method, which classifies the fault data from the normal data. Deep belief network (DBN), a technique for deep learning, is applied to classify the fault data. The DBN has a multilayer feature extraction scheme, which is highly sensitive to a small variation of data. Since the classification method is unable to detect the faulty sensor; therefore, a technique is proposed to identify the faulty sensor from the fault data. Finally, the composite statistical hypothesis test, namely generalized likelihood ratio test, is applied to compute the fault pattern of the faulty sensor signal based on the magnitude of the fault. The performance of the proposed method is validated by field data obtained from thermocouple sensors of the fast breeder test reactor.

  18. 76 FR 32878 - Draft Regulatory Guide: Issuance, Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-07

    ...-0129] Draft Regulatory Guide: Issuance, Availability AGENCY: Nuclear Regulatory Commission. ACTION: Notice of Issuance and Availability of Draft Regulatory Guide, DG-1253, ``Preoperational Testing of Emergency Core Cooling Systems for Pressurized-Water Reactors''. FOR FURTHER INFORMATION CONTACT: Mekonen M...

  19. A Classification System to Guide Physical Therapy Management in Huntington Disease: A Case Series.

    PubMed

    Fritz, Nora E; Busse, Monica; Jones, Karen; Khalil, Hanan; Quinn, Lori

    2017-07-01

    Individuals with Huntington disease (HD), a rare neurological disease, experience impairments in mobility and cognition throughout their disease course. The Medical Research Council framework provides a schema that can be applied to the development and evaluation of complex interventions, such as those provided by physical therapists. Treatment-based classifications, based on expert consensus and available literature, are helpful in guiding physical therapy management across the stages of HD. Such classifications also contribute to the development and further evaluation of well-defined complex interventions in this highly variable and complex neurodegenerative disease. The purpose of this case series was to illustrate the use of these classifications in the management of 2 individuals with late-stage HD. Two females, 40 and 55 years of age, with late-stage HD participated in this case series. Both experienced progressive declines in ambulatory function and balance as well as falls or fear of falling. Both individuals received daily care in the home for activities of daily living. Physical therapy Treatment-Based Classifications for HD guided the interventions and outcomes. Eight weeks of in-home balance training, strength training, task-specific practice of functional activities including transfers and walking tasks, and family/carer education were provided. Both individuals demonstrated improvements that met or exceeded the established minimal detectible change values for gait speed and Timed Up and Go performance. Both also demonstrated improvements on Berg Balance Scale and Physical Performance Test performance, with 1 of the 2 individuals exceeding the established minimal detectible changes for both tests. Reductions in fall risk were evident in both cases. These cases provide proof-of-principle to support use of treatment-based classifications for physical therapy management in individuals with HD. Traditional classification of early-, mid-, and late-stage disease progression may not reflect patients' true capabilities; those with late-stage HD may be as responsive to interventions as those at an earlier disease stage.Video Abstract available for additional insights from the authors (see Supplemental Digital Content 1, available at: http://links.lww.com/JNPT/A172).

  20. Science, Society, and America's Nuclear Waste: The Waste Management System, Unit 4. Teacher Guide. Second Edition.

    ERIC Educational Resources Information Center

    Department of Energy, Washington, DC. Office of Civilian Radioactive Waste Management, Washington, DC.

    This guide is Unit 4 of the four-part series, Science, Society, and America's Nuclear Waste, produced by the U.S. Department of Energy's Office Civilian Radioactive Waste Management. The goal of this unit is to explain how transportation, a geologic repository, and the multi-purpose canister will work together to provide short-term and long-term…

  1. 76 FR 65753 - Monitoring the Effectiveness of Maintenance at Nuclear Power Plants

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-24

    ... NUCLEAR REGULATORY COMMISSION [NRC-2011-0212] Monitoring the Effectiveness of Maintenance at...) re-issued Draft Regulatory Guide, DG-1278, ``Monitoring the Effectiveness of Maintenance at Nuclear... Revision 4A to Nuclear Management and Resources Council (NUMARC) 93-01, ``Industry Guideline for Monitoring...

  2. 77 FR 30030 - Monitoring the Effectiveness of Maintenance at Nuclear Power Plants

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-21

    ... NUCLEAR REGULATORY COMMISSION [NRC-2011-0212] Monitoring the Effectiveness of Maintenance at... (RG) 1.160, ``Monitoring the Effectiveness of Maintenance at Nuclear Power Plants.'' This guide endorses Revision 4A to Nuclear Management and Resources Council (NUMARC) 93-01, ``Industry Guideline for...

  3. 75 FR 79049 - Notice of Issuance of Regulatory Guide

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-17

    ..., Division of Engineering, Office of Nuclear Regulatory Research, U.S. Nuclear Regulatory Commission... INFORMATION: I. Introduction The U.S. Nuclear Regulatory Commission (NRC) is issuing a revision to an existing... Development Branch, Division of Engineering, Office of Nuclear Regulatory Research. [FR Doc. 2010-31731 Filed...

  4. Certification of Professional School Personnel in Manitoba: A Handbook for Graduates of Manitoba's Teacher Training Institutions = Delivrance des brevets au personnel professionnel du Manitoba: Guide a l'attention des diplomes des etablissements de formation d'enseignants du Manitoba.

    ERIC Educational Resources Information Center

    Manitoba Dept. of Education and Training, Winnipeg.

    This guide, with alternating pages of text in English and French, provides information about the process of obtaining teacher certification in Manitoba (Canada). The guide discusses professional and vocational certification; application procedures; teaching prior to certification; salary classification; salary reclassification; official statements…

  5. EPRI guide to managing nuclear utility protective clothing programs

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kelly, J.J.

    1991-05-01

    The Electric Power Research Institute (EPRI) commissioned a radioactive waste related project (RP2414-34) during the last quarter of 1989 to produce a guide for developing and managing nuclear protective clothing programs. Every nuclear facility must coordinate some type of protective clothing program for its radiation workers to insure proper and safe protection for the wearer and to maintain control over the spread of contamination. Yet, every nuclear facility has developed its own unique program for managing such clothing. Accordingly, a need existed for a reference guide to assist with the standardization of protective clothing programs and to assist in controllingmore » the potentially runaway economics of such programs. This document is the first known effort to formalize the planning and economic factors surrounding a nuclear utility protective clothing program. It is intended to be informative by addressing the various pieces of information necessary to establish and maintain an effective, professionally managed protective clothing program. It also attempts to provide guidance toward tailoring the information and providing examples within the report to fit each utility's specific needs. This report is further intended to address new issues and trends occurring throughout the nuclear industry in late 1989 which can have either a significant positive or negative impact on the operations or economics of nuclear protective clothing programs. 1 ref., 11 tabs.« less

  6. Crown-condition classification: a guide to data collection and analysis

    Treesearch

    Michael E. Schomaker; Stanley J. Zarnoch; William A. Bechtold; David J. Latelle; William G. Burkman; Susan M. Cox

    2007-01-01

    The Forest Inventory and Analysis (FIA) Program of the Forest Service, U.S. Department of Agriculture, conducts a national inventory of forests across the United States. A systematic subset of permanent inventory plots in 38 States is currently sampled every year for numerous forest health indicators. One of these indicators, crown-condition classification, is designed...

  7. Combined Edition of Family Planning Library Manual and Family Planning Classification.

    ERIC Educational Resources Information Center

    Planned Parenthood--World Population, New York, NY. Katherine Dexter McCormick Library.

    This edition combines two previous publications of the Katharine Dexter McCormick Library into one volume: the Family Planning Library Manual, a guide for starting a family planning and population library or information center, and the Family Planning Classification, a coding system for organizing book and non-book materials so that they can be…

  8. Food Service Management. Second Edition. Answer Book/Teacher's Guide. Second Edition.

    ERIC Educational Resources Information Center

    Hatchett, Melvin S.; Zelade, Richard

    This document contains a student assignment book with 22 assignments for a course in food service management and a teacher's guide with answers to the assignments and tips on presenting the lessons to which they pertain. The assignments cover the following topics: career opportunities; entering the food service industry; classifications of…

  9. Anaerobic Digestion II. Sludge Treatment and Disposal Course #166. Instructor's Guide [and] Student Workbook.

    ERIC Educational Resources Information Center

    Arasmith, E. E.

    This lesson is the second of a two-part series on anaerobic digestion. Topics discussed include classification of digester by function, roof design, and temperature range, mixing systems, gas system components, operational control basics, and general safety considerations. The lesson includes an instructor's guide and student workbook. The…

  10. Manufacturing Materials and Processes. Grade 11-12. Course #8165 (Semester). Technology Education Course Guide. Industrial Arts/Technology Education.

    ERIC Educational Resources Information Center

    North Carolina State Dept. of Public Instruction, Raleigh. Div. of Vocational Education.

    This guide is intended for use in teaching an introductory course in manufacturing materials and processes. The course centers around four basic materials--metallics, polymers, ceramics, and composites--and seven manufacturing processes--casting, forming, molding, separating, conditioning, assembling, and finishing. Concepts and classifications of…

  11. 10 CFR 1045.4 - Responsibilities.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... declassification of RD and FRD in accordance with the Atomic Energy Act; (2) In coordination with the DoD, develop regulations to implement the RD and FRD classification system; (3) Determine whether nuclear-related information is RD; (4) Oversee agency implementation of the RD and FRD classification system to ensure...

  12. 10 CFR 1045.4 - Responsibilities.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... declassification of RD and FRD in accordance with the Atomic Energy Act; (2) In coordination with the DoD, develop regulations to implement the RD and FRD classification system; (3) Determine whether nuclear-related information is RD; (4) Oversee agency implementation of the RD and FRD classification system to ensure...

  13. 10 CFR 1045.4 - Responsibilities.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... declassification of RD and FRD in accordance with the Atomic Energy Act; (2) In coordination with the DoD, develop regulations to implement the RD and FRD classification system; (3) Determine whether nuclear-related information is RD; (4) Oversee agency implementation of the RD and FRD classification system to ensure...

  14. 10 CFR 1045.4 - Responsibilities.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... declassification of RD and FRD in accordance with the Atomic Energy Act; (2) In coordination with the DoD, develop regulations to implement the RD and FRD classification system; (3) Determine whether nuclear-related information is RD; (4) Oversee agency implementation of the RD and FRD classification system to ensure...

  15. 10 CFR 1045.4 - Responsibilities.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... declassification of RD and FRD in accordance with the Atomic Energy Act; (2) In coordination with the DoD, develop regulations to implement the RD and FRD classification system; (3) Determine whether nuclear-related information is RD; (4) Oversee agency implementation of the RD and FRD classification system to ensure...

  16. 10 CFR 1045.7 - Suggestions or complaints.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Suggestions or complaints. 1045.7 Section 1045.7 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) NUCLEAR CLASSIFICATION AND DECLASSIFICATION Program Management of... declassification policies and procedures may direct them in writing to the Director, Office of Classification, HS...

  17. 10 CFR 1045.3 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... ENERGY (GENERAL PROVISIONS) NUCLEAR CLASSIFICATION AND DECLASSIFICATION Program Management of the Restricted Data and Formerly Restricted Data Classification System § 1045.3 Definitions. As used in this part: Agency means any “Executive Agency” as defined in 5 U.S.C. 105; any “Military Department” as defined in 5...

  18. 77 FR 73056 - Initial Test Programs for Water-Cooled Nuclear Power Plants

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-07

    ... NUCLEAR REGULATORY COMMISSION [NRC-2012-0293] Initial Test Programs for Water-Cooled Nuclear Power... (DG), DG-1259, ``Initial Test Programs for Water-Cooled Nuclear Power Plants.'' This guide describes the general scope and depth that the staff of the NRC considers acceptable for Initial Test Programs...

  19. 78 FR 37325 - License Renewal of Nuclear Power Plants; Generic Environmental Impact Statement and Standard...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-20

    ... Nuclear Power Plants; Generic Environmental Impact Statement and Standard Review Plans for Environmental... for Nuclear Power Plants, Supplement 1: Operating License Renewal'' (ESRP). The ESRP serves as a guide... published a final rule, ``Revisions to Environmental Review for Renewal of Nuclear Power Plant Operating...

  20. 10 CFR 5.520 - Job classification and structure.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Energy NUCLEAR REGULATORY COMMISSION NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR... Education Programs or Activities Prohibited § 5.520 Job classification and structure. A recipient shall not: (a) Classify a job as being for males or for females; (b) Maintain or establish separate lines of...

  1. 10 CFR 5.520 - Job classification and structure.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Energy NUCLEAR REGULATORY COMMISSION NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR... Education Programs or Activities Prohibited § 5.520 Job classification and structure. A recipient shall not: (a) Classify a job as being for males or for females; (b) Maintain or establish separate lines of...

  2. 10 CFR 5.520 - Job classification and structure.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Energy NUCLEAR REGULATORY COMMISSION NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR... Education Programs or Activities Prohibited § 5.520 Job classification and structure. A recipient shall not: (a) Classify a job as being for males or for females; (b) Maintain or establish separate lines of...

  3. 10 CFR 5.520 - Job classification and structure.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Energy NUCLEAR REGULATORY COMMISSION NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR... Education Programs or Activities Prohibited § 5.520 Job classification and structure. A recipient shall not: (a) Classify a job as being for males or for females; (b) Maintain or establish separate lines of...

  4. 10 CFR 5.520 - Job classification and structure.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Energy NUCLEAR REGULATORY COMMISSION NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR... Education Programs or Activities Prohibited § 5.520 Job classification and structure. A recipient shall not: (a) Classify a job as being for males or for females; (b) Maintain or establish separate lines of...

  5. 10 CFR 1045.15 - Classification and declassification presumptions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... experimental physics, engineering, materials science, biology and medicine; (2) Magnetic confinement fusion... the application of the criteria in § 1045.16 indicates otherwise: (1) Detailed designs, specifications... design and analysis of nuclear weapons; (3) Vulnerabilities of U.S. nuclear weapons to sabotage...

  6. 10 CFR 1045.15 - Classification and declassification presumptions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... experimental physics, engineering, materials science, biology and medicine; (2) Magnetic confinement fusion... the application of the criteria in § 1045.16 indicates otherwise: (1) Detailed designs, specifications... design and analysis of nuclear weapons; (3) Vulnerabilities of U.S. nuclear weapons to sabotage...

  7. SDIO (Strategic Defense Initiative Office) Technical Information Management Center Bibliography of Unclassified Reports: January - December 1986.

    DTIC Science & Technology

    1986-12-01

    Classification. U Security Marks, Accession *:U00298 AD *. ADA096538 TITLE: Assessment of the Crossed Porro Prism Resonator AUTHOR. Seea, B.A.; Fueloep, K...Laser Range Finder Mechanical Property Stability Resonator Porro Prism Standord Mirror Examine Pgs: 16 Classification: U Security Marks: Accession...Gamma-Ray Laser Graser Mossbauer Effect Borrman Superradiance Nuclear-Magnetic Resonance Pgs: 26 Classification: U Security Marks: Accession *:U00484 AD

  8. The classification of phobic disorders.

    PubMed

    Sheehan, D V; Sheehan, K H

    The history of classification of phobic disorders is reviewed. Problems in the ability of current classification schemes to predict, control and describe the relationship between the symptoms and other phenomena are outlined. A new classification of phobic disorders is proposed based on the presence or absence of an endogenous anxiety syndrome with the phobias. The two categories of phobic disorder have a different clinical presentation and course, a different mean age of onset, distribution of age of onset, sex distribution, response to treatment modalities, GSR testing and habituation response. Empirical evidence supporting this proposal is cited. This classification has heuristic merit in guiding research efforts and discussions and in directing the clinician to a simple and practical solution of his patient's phobic disorder.

  9. Effects of granularity on the natural classification of loose cover layer rock

    NASA Astrophysics Data System (ADS)

    Zhang, Shuhui; Wang, Peng; Zhang, Zhiqiang

    2018-03-01

    In the sublevel caving method, with developing depth of underground mines increasing, the ore loss and dilution is become more and more remarkable that is due to the natural classification of loose cover layer rock. Therefore, this paper researches that granularity are one of the main factors affecting the natural classification, and carries out a physical simulation experiment of loose cover layer rock granularity effects of natural classification. Through the experiment we found that granularity has important effect on natural classification. Under the condition of the same weight, we found the closer of granularities that consist of cover layer rock, the less prone to natural classification. Otherwise, it will be prone to natural classification. This study has a guiding significance for a mine, forming a scientific and reasonable cover layer rock, and reducing the ore loss and dilution in the mining process.

  10. A Guide for Setting the Cut-Scores to Minimize Weighted Classification Errors in Test Batteries

    ERIC Educational Resources Information Center

    Grabovsky, Irina; Wainer, Howard

    2017-01-01

    In this article, we extend the methodology of the Cut-Score Operating Function that we introduced previously and apply it to a testing scenario with multiple independent components and different testing policies. We derive analytically the overall classification error rate for a test battery under the policy when several retakes are allowed for…

  11. Predicting protein complexes using a supervised learning method combined with local structural information.

    PubMed

    Dong, Yadong; Sun, Yongqi; Qin, Chao

    2018-01-01

    The existing protein complex detection methods can be broadly divided into two categories: unsupervised and supervised learning methods. Most of the unsupervised learning methods assume that protein complexes are in dense regions of protein-protein interaction (PPI) networks even though many true complexes are not dense subgraphs. Supervised learning methods utilize the informative properties of known complexes; they often extract features from existing complexes and then use the features to train a classification model. The trained model is used to guide the search process for new complexes. However, insufficient extracted features, noise in the PPI data and the incompleteness of complex data make the classification model imprecise. Consequently, the classification model is not sufficient for guiding the detection of complexes. Therefore, we propose a new robust score function that combines the classification model with local structural information. Based on the score function, we provide a search method that works both forwards and backwards. The results from experiments on six benchmark PPI datasets and three protein complex datasets show that our approach can achieve better performance compared with the state-of-the-art supervised, semi-supervised and unsupervised methods for protein complex detection, occasionally significantly outperforming such methods.

  12. A Basic Guide to Nuclear Power.

    ERIC Educational Resources Information Center

    Martocci, Barbara; Wilson, Greg

    More than 100 nuclear power plants supply over 17 percent of the electricity in the United States. The basic principles of how nuclear energy works and how it is used to make electricity are explained in this profusely illustrated booklet written for the average sixth grade reader. Discussions include: (1) atomic structure; (2) nuclear fission;…

  13. Citizen Education on Nuclear Technology (CENT). Teacher's Guide.

    ERIC Educational Resources Information Center

    Intermountain Science Experience Center, ID Falls, ID.

    Using an interdisciplinary approach, this curriculum focuses on understanding: (1) the fundamental principles of operating a nuclear power plant; (2) the place of nuclear energy in the overall energy supply/demand situation; (3) risk-benefit balance of the major energy sources; and (4) the role of political action in developing nuclear energy…

  14. Introduction to Grassland Management. Instructor Guide, Student Reference [and] Crop and Grassland Plant Identification Manual.

    ERIC Educational Resources Information Center

    Suits, Susie

    This packet contains an Instructor guide and student reference for a course in introduction to grassland management, as well as a crop and grassland plant identification manual. The three-unit curriculum contains the following 11 lessons: (unit I, grasslands and grassland plants): (1) an introduction to grasslands; (2) plant classification; (3)…

  15. Appraising fuels and flammability in western aspen: a prescribed fire guide

    Treesearch

    James K. Brown; Dennis G. Simmerman

    1986-01-01

    Describes a method for appraising fuels and fire behavior potential in aspen forests to guide the use of prescribed fire and the preparation of fire prescriptions. Includes an illustrated classification of aspen fuels; appraisals of fireline intensity, rate of spread, adjective ratings for fire behavior and probability of burn success; and evaluations of seasonal...

  16. Plant association and management guide for the western hemlock zone.

    Treesearch

    Christopher Topik; Nancy M. Halverson; Dale G. Brockway

    1986-01-01

    This guide presents the plant association classification for the western hemlock zone of the Gifford Pinchot National Forest. The bulk of the forest below about 3000 feet in elevation is included in this zone, comprising about one half of the entire landbase. Much of this area is blanketed with productive stands of Douglas-fir.

  17. A Guide to Studying Human Hair Follicle Cycling In Vivo.

    PubMed

    Oh, Ji Won; Kloepper, Jennifer; Langan, Ewan A; Kim, Yongsoo; Yeo, Joongyeub; Kim, Min Ji; Hsi, Tsai-Ching; Rose, Christian; Yoon, Ghil Suk; Lee, Seok-Jong; Seykora, John; Kim, Jung Chul; Sung, Young Kwan; Kim, Moonkyu; Paus, Ralf; Plikus, Maksim V

    2016-01-01

    Hair follicles (HFs) undergo lifelong cyclical transformations, progressing through stages of rapid growth (anagen), regression (catagen), and relative "quiescence" (telogen). Given that HF cycling abnormalities underlie many human hair growth disorders, the accurate classification of individual cycle stages within skin biopsies is clinically important and essential for hair research. For preclinical human hair research purposes, human scalp skin can be xenografted onto immunocompromised mice to study human HF cycling and manipulate long-lasting anagen in vivo. Although available for mice, a comprehensive guide on how to recognize different human hair cycle stages in vivo is lacking. In this article, we present such a guide, which uses objective, well-defined, and reproducible criteria, and integrates simple morphological indicators with advanced, (immuno)-histochemical markers. This guide also characterizes human HF cycling in xenografts and highlights the utility of this model for in vivo hair research. Detailed schematic drawings and representative micrographs provide examples of how best to identify human HF stages, even in suboptimally sectioned tissue, and practical recommendations are given for designing human-on-mouse hair cycle experiments. Thus, this guide seeks to offer a benchmark for human hair cycle stage classification, for both hair research experts and newcomers to the field. Copyright © 2015 The Authors. Published by Elsevier Inc. All rights reserved.

  18. Prosodic analysis by rule

    NASA Astrophysics Data System (ADS)

    Lindsay, D.

    1985-02-01

    Research on the automatic computer analysis of intonation using linguistic knowledge is described. The use of computer programs to analyze and classify fundamental frequency (FO) contours, and work on the psychophysics of British English intonation and on the phonetics of FO contours are described. Results suggest that FO can be conveniently tracked to represent intonation through time, which can be subsequently used by a computer program as the basis for analysis. Nuclear intonation, where the intonational nucleus is the region of auditory prominence, or information focus, found in all spoken sentences was studied. The main mechanism behind such prominence is the perception of an extensive FO movement on the nuclear syllable. A classification of the nuclear contour shape is a classification of the sentence type, often into categories that cannot be readily determined from only the segmental phonemes of the utterance.

  19. Federal guide for a radiological response: Supporting the Nuclear Regulatory Commission during the initial hours of a serious accident

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hogan, R.T.

    1993-11-01

    This document is a planning guide for those Federal agencies that work with the Nuclear Regulatory commission (NRC) during the initial hours of response to a serious radiological emergency in which the NRC is the Lead Federal Agency (LFA). These Federal agencies are: DOE, EPA, USDA, HHS, NOAA, and FEMA. This guide is intended to help these agencies prepare for a prompt response. Instructions are provided on receiving the initial notification, the type of person to send to the scene, the facility at which people are needed, how to get them to that facility, and what they should do whenmore » they arrive. Federal agencies not specifically mentioned in this guide may also be asked to support the NRC.« less

  20. 77 FR 33253 - Regulatory Guide 8.33, Quality Management Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-05

    ... NUCLEAR REGULATORY COMMISSION [NRC-2012-0126] Regulatory Guide 8.33, Quality Management Program... Regulatory Commission (NRC or Commission) is withdrawing Regulatory Guide (RG) 8.33, ``Quality Management... Quality Management Program was deleted from the regulations as part of an overall revision in 2002 of the...

  1. Emesis and Defecations Induced by the 5-Hydroxytryptamine (5-HT3) Receptor Anatagonist Zacopride in the Ferret

    DTIC Science & Technology

    1990-02-16

    TERMS 8. NUMBER OF PAGES 8 16. PRICE CODE 17 SECURITY CLASSIFICATION is. SECURITY CLASSIFICATION 19. SECURITY CLASSIFICATION 20. LIMITATION OF OP...the Defense Nuclear erties, i.e., granisetron [BRL43694; Endo-N-[9-methyl-9-aza- Agency has been given or should be inferred. Research was conducted...BMY25801, batanopride; BRL43694, granisetron ; GI, gastrointestinal; ACh, acetylcholine. 1034 1990 Emetic Properties of Zacopnde 1035 benzamide HCI; Gylys et

  2. Rapid Identification of Candida Species by Using Nuclear Magnetic Resonance Spectroscopy and a Statistical Classification Strategy

    PubMed Central

    Himmelreich, Uwe; Somorjai, Ray L.; Dolenko, Brion; Lee, Ok Cha; Daniel, Heide-Marie; Murray, Ronan; Mountford, Carolyn E.; Sorrell, Tania C.

    2003-01-01

    Nuclear magnetic resonance (NMR) spectra were acquired from suspensions of clinically important yeast species of the genus Candida to characterize the relationship between metabolite profiles and species identification. Major metabolites were identified by using two-dimensional correlation NMR spectroscopy. One-dimensional proton NMR spectra were analyzed by using a staged statistical classification strategy. Analysis of NMR spectra from 442 isolates of Candida albicans, C. glabrata, C. krusei, C. parapsilosis, and C. tropicalis resulted in rapid, accurate identification when compared with conventional and DNA-based identification. Spectral regions used for the classification of the five yeast species revealed species-specific differences in relative amounts of lipids, trehalose, polyols, and other metabolites. Isolates of C. parapsilosis and C. glabrata with unusual PCR fingerprinting patterns also generated atypical NMR spectra, suggesting the possibility of intraspecies discontinuity. We conclude that NMR spectroscopy combined with a statistical classification strategy is a rapid, nondestructive, and potentially valuable method for identification and chemotaxonomic characterization that may be broadly applicable to fungi and other microorganisms. PMID:12902244

  3. Discrimination of irradiated MOX fuel from UOX fuel by multivariate statistical analysis of simulated activities of gamma-emitting isotopes

    NASA Astrophysics Data System (ADS)

    Åberg Lindell, M.; Andersson, P.; Grape, S.; Hellesen, C.; Håkansson, A.; Thulin, M.

    2018-03-01

    This paper investigates how concentrations of certain fission products and their related gamma-ray emissions can be used to discriminate between uranium oxide (UOX) and mixed oxide (MOX) type fuel. Discrimination of irradiated MOX fuel from irradiated UOX fuel is important in nuclear facilities and for transport of nuclear fuel, for purposes of both criticality safety and nuclear safeguards. Although facility operators keep records on the identity and properties of each fuel, tools for nuclear safeguards inspectors that enable independent verification of the fuel are critical in the recovery of continuity of knowledge, should it be lost. A discrimination methodology for classification of UOX and MOX fuel, based on passive gamma-ray spectroscopy data and multivariate analysis methods, is presented. Nuclear fuels and their gamma-ray emissions were simulated in the Monte Carlo code Serpent, and the resulting data was used as input to train seven different multivariate classification techniques. The trained classifiers were subsequently implemented and evaluated with respect to their capabilities to correctly predict the classes of unknown fuel items. The best results concerning successful discrimination of UOX and MOX-fuel were acquired when using non-linear classification techniques, such as the k nearest neighbors method and the Gaussian kernel support vector machine. For fuel with cooling times up to 20 years, when it is considered that gamma-rays from the isotope 134Cs can still be efficiently measured, success rates of 100% were obtained. A sensitivity analysis indicated that these methods were also robust.

  4. Resource Letter MP-1: The Manhattan Project and related nuclear research

    NASA Astrophysics Data System (ADS)

    Reed, B. Cameron

    2005-09-01

    This Resource Letter provides a guide to literature on the Manhattan Project and related nuclear research. Books and journal articles are cited for the following topics: general works, technical works, biographical and autobiographical works, the German nuclear program, and technical papers of historical interest. A list of videos and websites dealing with the Manhattan Project, nuclear weapons, and nuclear issues is also given.

  5. Multi-dimensional classification of GABAergic interneurons with Bayesian network-modeled label uncertainty.

    PubMed

    Mihaljević, Bojan; Bielza, Concha; Benavides-Piccione, Ruth; DeFelipe, Javier; Larrañaga, Pedro

    2014-01-01

    Interneuron classification is an important and long-debated topic in neuroscience. A recent study provided a data set of digitally reconstructed interneurons classified by 42 leading neuroscientists according to a pragmatic classification scheme composed of five categorical variables, namely, of the interneuron type and four features of axonal morphology. From this data set we now learned a model which can classify interneurons, on the basis of their axonal morphometric parameters, into these five descriptive variables simultaneously. Because of differences in opinion among the neuroscientists, especially regarding neuronal type, for many interneurons we lacked a unique, agreed-upon classification, which we could use to guide model learning. Instead, we guided model learning with a probability distribution over the neuronal type and the axonal features, obtained, for each interneuron, from the neuroscientists' classification choices. We conveniently encoded such probability distributions with Bayesian networks, calling them label Bayesian networks (LBNs), and developed a method to predict them. This method predicts an LBN by forming a probabilistic consensus among the LBNs of the interneurons most similar to the one being classified. We used 18 axonal morphometric parameters as predictor variables, 13 of which we introduce in this paper as quantitative counterparts to the categorical axonal features. We were able to accurately predict interneuronal LBNs. Furthermore, when extracting crisp (i.e., non-probabilistic) predictions from the predicted LBNs, our method outperformed related work on interneuron classification. Our results indicate that our method is adequate for multi-dimensional classification of interneurons with probabilistic labels. Moreover, the introduced morphometric parameters are good predictors of interneuron type and the four features of axonal morphology and thus may serve as objective counterparts to the subjective, categorical axonal features.

  6. 75 FR 33361 - Notice of Issuance of Regulatory Guide

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-11

    ... staff needs in its review of applications for permits and licenses. Revision 4 of Regulatory Guide 1.28... (Design and Construction).'' Proposed RG 1.28, Revision 4, extends the scope of the NRC's endorsement to...: Nuclear Regulatory Commission. ACTION: Notice of Issuance and Availability of Regulatory Guide 1.28...

  7. Phase I Forest Area Estimation Using Landsat TM and Iterative Guided Spectral Class Rejection: Assessment of Possible Training Data Protocols

    Treesearch

    John A. Scrivani; Randolph H. Wynne; Christine E. Blinn; Rebecca F. Musy

    2001-01-01

    Two methods of training data collection for automated image classification were tested in Virginia as part of a larger effort to develop an objective, repeatable, and low-cost method to provide forest area classification from satellite imagery. The derived forest area estimates were compared to estimates derived from a traditional photo-interpreted, double sample. One...

  8. Financial Accounting: Classifications and Standard Terminology for Local and State School Systems. State Educational Records and Reports Series: Handbook II, Revised.

    ERIC Educational Resources Information Center

    Roberts, Charles T., Comp.; Lichtenberger, Allan R., Comp.

    This handbook has been prepared as a vehicle or mechanism for program cost accounting and as a guide to standard school accounting terminology for use in all types of local and intermediate education agencies. In addition to classification descriptions, program accounting definitions, and proration of cost procedures, some units of measure and…

  9. How the Use of the International Classification of Functioning, Disability and Health for Children and Youth Changed the Individualized Education Programs in Portugal

    ERIC Educational Resources Information Center

    Silveira-Maia, Mónica; Lopes-dos-Santos, Pedro; Sanches-Ferreira, Manuela

    2017-01-01

    Current Portuguese Public Law No. 3/2008 requires the use of the International Classification of Functioning, Health and Disability for Children and Youth (ICF-CY) as a reference framework to guide assessment and intervention procedures for students with additional support needs. This study explores whether the ICF-CY use fostered multidimensional…

  10. Engineering Design Handbook. Development Guide for Reliability. Part 6. Mathematical Appendix and Glossary

    DTIC Science & Technology

    1976-01-08

    Corps, nonmilitary Government agencies, contractors, private industry, individuals, universities , and others must purchase these Handbooks from...verified by an official Department of Army representative and processed from Defense Documentation Center ( DDC ), ATTN: DDC -TSR, Cameron Station...tell, by looking at a failed item, what classification of failure is involved. Some of the classifications are for mathematical conven- ience only

  11. A statistically valid method for using FIA plots to guide spectral class rejection in producing stratification maps

    Treesearch

    Michael L. Hoppus; Andrew J. Lister

    2002-01-01

    A Landsat TM classification method (iterative guided spectral class rejection) produced a forest cover map of southern West Virginia that provided the stratification layer for producing estimates of timberland area from Forest Service FIA ground plots using a stratified sampling technique. These same high quality and expensive FIA ground plots provided ground reference...

  12. An evaluation of sampling and full enumeration strategies for Fisher Jenks classification in big data settings

    USGS Publications Warehouse

    Rey, Sergio J.; Stephens, Philip A.; Laura, Jason R.

    2017-01-01

    Large data contexts present a number of challenges to optimal choropleth map classifiers. Application of optimal classifiers to a sample of the attribute space is one proposed solution. The properties of alternative sampling-based classification methods are examined through a series of Monte Carlo simulations. The impacts of spatial autocorrelation, number of desired classes, and form of sampling are shown to have significant impacts on the accuracy of map classifications. Tradeoffs between improved speed of the sampling approaches and loss of accuracy are also considered. The results suggest the possibility of guiding the choice of classification scheme as a function of the properties of large data sets.

  13. EUS-guided biopsy for the diagnosis and classification of lymphoma.

    PubMed

    Ribeiro, Afonso; Pereira, Denise; Escalón, Maricer P; Goodman, Mark; Byrne, Gerald E

    2010-04-01

    EUS-guided FNA and Tru-cut biopsy (TCB) is highly accurate in the diagnosis of lymphoma. Subclassification, however, may be difficult in low-grade non-Hodgkin lymphoma and Hodgkin lymphoma. To determine the yield of EUS-guided biopsy to classify lymphoma based on the World Health Organization classification of tumors of hematopoietic lymphoid tissues. Retrospective study. Tertiary referral center. A total of 24 patients referred for EUS-guided biopsy who had a final diagnosis of lymphoma or "highly suspicious for lymphoma." EUS-guided FNA and TCB combined with flow cytometry (FC) analysis. MAIN OUTCOMES MEASUREMENT: Lymphoma subclassification accuracy of EUS guided biopsy. Twenty-four patients were included in this study. Twenty-three patients underwent EUS-FNA, and 1 patient had only TCB. Twenty-two underwent EUS-TCB combined with FNA. EUS correctly diagnosed lymphoma in 19 out of 24 patients (79%), and subclassification was determined in 16 patients (66.6%). Flow cytometry correctly identified B-cell monoclonality in 95% (18 out of 19). In 1 patient diagnosed as having marginal-zone lymphoma by EUS-FNA/FC only, the diagnosis was changed to hairy cell leukemia after a bone marrow biopsy was obtained. EUS had a lower yield in nonlarge B-cell lymphoma (only 9 out of 15 cases [60%]) compared with large B-cell lymphoma (78%; P = .3 [Fisher exact test]). Retrospective, small number of patients. EUS-guided biopsy has a lower yield to correctly classify Hodgkin lymphoma and low-grade lymphoma compared with high-grade diffuse large B-cell lymphoma. Copyright 2010 American Society for Gastrointestinal Endoscopy. Published by Mosby, Inc. All rights reserved.

  14. Resource Letter PSNAC-1: Physics and society: Nuclear arms control

    NASA Astrophysics Data System (ADS)

    Glaser, Alexander; Mian, Zia

    2008-01-01

    This Resource Letter provides a guide to the literature on nuclear arms control for the nonspecialist. Journal articles and books are cited for the following topics: nuclear weapons, fissile materials, nonproliferation, missiles and missile defenses, verification, disarmament, and the role of scientists in arms control.

  15. Clinico-pathological Correlation of Thyroid Nodule Ultrasound and Cytology Using the TIRADS and Bethesda Classifications.

    PubMed

    Singaporewalla, R M; Hwee, J; Lang, T U; Desai, V

    2017-07-01

    Clinico-pathological correlation of thyroid nodules is not routinely performed as until recently there was no objective classification system for reporting thyroid nodules on ultrasound. We compared the Thyroid Imaging Reporting and Data System (TIRADS) of classifying thyroid nodules on ultrasound with the findings on fine-needle aspiration cytology (FNAC) reported using the Bethesda System. A retrospective analysis of 100 consecutive cases over 1 year (Jan-Dec 2015) was performed comparing single-surgeon-performed bedside thyroid nodule ultrasound findings based on the TIRADS classification to the FNAC report based on the Bethesda Classification. TIRADS 1 (normal thyroid gland) and biopsy-proven malignancy referred by other clinicians were excluded. Benign-appearing nodules were reported as TIRADS 2 and 3. Indeterminate or suspected follicular lesions were reported as TIRADS 4, and malignant-appearing nodules were classified as TIRADS 5 during surgeon-performed bedside ultrasound. All the nodules were subjected to ultrasound-guided FNAC, and TIRADS findings were compared to Bethesda FNAC Classification. Of the 100 cases, 74 were considered benign or probably benign, 20 were suspicious for malignancy, and 6 were indeterminate on ultrasound. Overall concordance rate with FNAC was 83% with sensitivity and specificity of 70.6 and 90.4%, respectively. The negative predictive value was 93.8%. It is essential for clinicians performing bedside ultrasound thyroid and guided FNAC to document their sonographic impression of the nodule in an objective fashion using the TIRADS classification and correlate with the gold standard cytology to improve their learning curve and audit their results.

  16. Development of a spatially universal framework for classifying stream assemblages with application to conservation planning for Great Lakes lotic fish communities

    USGS Publications Warehouse

    McKenna, James E.; Schaeffer, Jeffrey S.; Stewart, Jana S.; Slattery, Michael T.

    2015-01-01

    Classifications are typically specific to particular issues or areas, leading to patchworks of subjectively defined spatial units. Stream conservation is hindered by the lack of a universal habitat classification system and would benefit from an independent hydrology-guided spatial framework of units encompassing all aquatic habitats at multiple spatial scales within large regions. We present a system that explicitly separates the spatial framework from any particular classification developed from the framework. The framework was constructed from landscape variables that are hydrologically and biologically relevant, covered all space within the study area, and was nested hierarchically and spatially related at scales ranging from the stream reach to the entire region; classifications may be developed from any subset of the 9 basins, 107 watersheds, 459 subwatersheds, or 10,000s of valley segments or stream reaches. To illustrate the advantages of this approach, we developed a fish-guided classification generated from a framework for the Great Lakes region that produced a mosaic of habitat units which, when aggregated, formed larger patches of more general conditions at progressively broader spatial scales. We identified greater than 1,200 distinct fish habitat types at the valley segment scale, most of which were rare. Comparisons of biodiversity and species assemblages are easily examined at any scale. This system can identify and quantify habitat types, evaluate habitat quality for conservation and/or restoration, and assist managers and policymakers with prioritization of protection and restoration efforts. Similar spatial frameworks and habitat classifications can be developed for any organism in any riverine ecosystem.

  17. 76 FR 14108 - Notice of Issuance of Regulatory Guide

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-15

    ..., telephone (301) 251-7569 or e-mail [email protected] . SUPPLEMENTARY INFORMATION: I. Introduction The U.S.... Thomas H. Boyce, Chief, Regulatory Guide Development Branch, Division of Engineering, Office of Nuclear...

  18. Nuclear Computerized Library for Assessing Reactor Reliability (NUCLARR). Version 3.5, Quick Reference Guide

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gilbert, B.G.; Richards, R.E.; Reece, W.J.

    1992-10-01

    This Reference Guide contains instructions on how to install and use Version 3.5 of the NRC-sponsored Nuclear Computerized Library for Assessing Reactor Reliability (NUCLARR). The NUCLARR data management system is contained in compressed files on the floppy diskettes that accompany this Reference Guide. NUCLARR is comprised of hardware component failure data (HCFD) and human error probability (HEP) data, both of which are available via a user-friendly, menu driven retrieval system. The data may be saved to a file in a format compatible with IRRAS 3.0 and commercially available statistical packages, or used to formulate log-plots and reports of data retrievalmore » and aggregation findings.« less

  19. Guiding the United States Government Response to an Overseas Chemical, Biological, Radiological, or Nuclear Disaster

    DTIC Science & Technology

    2001-02-01

    NUCLEAR DISASTER by Roman N. Hrycaj, Colonel, USAF A Research Report Submitted to the Faculty In Partial Fulfillment of the Graduation Requirements... Nuclear Disaster Contract Number Grant Number Program Element Number Author(s) Hrycaj, Roman N. Project Number Task Number Work Unit Number

  20. 75 FR 2894 - Withdrawal of Regulatory Guide 1.148

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-19

    ... Valve Assemblies in Systems Important to Safety in Nuclear Power Plants.'' FOR FURTHER INFORMATION... for Active Valve Assemblies in Systems Important to Safety in Nuclear Power Plants.'' RG 1.148 was... qualifying active mechanical equipment used in nuclear power plants. The NRC is withdrawing RG 1.148 because...

  1. 75 FR 62610 - Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Plant...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-12

    ...: Draft Regulatory Guide DG-1237, ``Guidance on Making Changes to Emergency Plans for Nuclear Power Reactors,'' Interim Staff Guidance (ISG) NSIR/DPR-ISG-01, ``Emergency Planning for Nuclear Power Plants... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS...

  2. 78 FR 47015 - Software Requirement Specifications for Digital Computer Software Used in Safety Systems of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-02

    ... NUCLEAR REGULATORY COMMISSION [NRC-2012-0195] Software Requirement Specifications for Digital Computer Software Used in Safety Systems of Nuclear Power Plants AGENCY: Nuclear Regulatory Commission... issuing a revised regulatory guide (RG), revision 1 of RG 1.172, ``Software Requirement Specifications for...

  3. 77 FR 60482 - Regulatory Guide 5.67, Material Control and Accounting for Uranium Enrichment Facilities...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-03

    ... Accounting for Uranium Enrichment Facilities Authorized To Produce Special Nuclear Material of Low Strategic... Accounting for Uranium Enrichment Facilities Authorized to Produce Special Nuclear Material of Low Strategic... INFORMATION CONTACT: Glenn Tuttle, Office of Nuclear Material Safety and Safeguards, Division of Fuel Cycle...

  4. 76 FR 50275 - Guidance for the Assessment of Beyond-Design-Basis Aircraft Impacts

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-12

    ...: Mekonen M. Bayssie, Regulatory Guide Development Branch, Division of Engineering, Office of Nuclear... e-mail to [email protected] . SUPPLEMENTARY INFORMATION: I. Introduction The Nuclear..., Division of Engineering, Office of Nuclear Regulatory Research. [FR Doc. 2011-20513 Filed 8-11-11; 8:45 am...

  5. 75 FR 45677 - Draft Regulatory Guide, DG-1216,”Plant-Specific Applicability of Transition Break Size Specified...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-03

    ... NUCLEAR REGULATORY COMMISSION [NRC-2010-0229] Draft Regulatory Guide, DG-1216,''Plant-Specific... Commission (NRC) is extending the public comment period for DG-1216 from August 25, 2010 to November 8, 2010... [email protected] . The Draft Regulatory Guide, DG-1216, ``Plant- Specific Applicability of...

  6. The Environmental Impact of Electrical Power Generation: Nuclear and Fossil. Teacher's Guide.

    ERIC Educational Resources Information Center

    Pennsylvania State Dept. of Education, Harrisburg.

    This teacher's guide accompanies a course concerning the need, environmental costs, and benefits of electrical power generation. Each chapter of this guide corresponds to a chapter in the course text, and includes the following: a list of behavioral objectives for the corresponding chapter, a list of suggested activities, recommended audio-visual…

  7. Accurate shade image matching by using a smartphone camera.

    PubMed

    Tam, Weng-Kong; Lee, Hsi-Jian

    2017-04-01

    Dental shade matching by using digital images may be feasible when suitable color features are properly manipulated. Separating the color features into feature spaces facilitates favorable matching. We propose using support vector machines (SVM), which are outstanding classifiers, in shade classification. A total of 1300 shade tab images were captured using a smartphone camera with auto-mode settings and no flash. The images were shot at angled distances of 14-20cm from a shade guide at a clinic equipped with light tubes that produced a 4000K color temperature. The Group 1 samples comprised 1040 tab images, for which the shade guide was randomly positioned in the clinic, and the Group 2 samples comprised 260 tab images, for which the shade guide had a fixed position in the clinic. Rectangular content was cropped manually on each shade tab image and further divided into 10×2 blocks. The color features extracted from the blocks were described using a feature vector. The feature vectors in each group underwent SVM training and classification by using the "leave-one-out" strategy. The top one and three accuracies of Group 1 were 0.86 and 0.98, respectively, and those of Group 2 were 0.97 and 1.00, respectively. This study provides a feasible technique for dental shade classification that uses the camera of a mobile device. The findings reveal that the proposed SVM classification might outperform the shade-matching results of previous studies that have performed similarity measurements of ΔE levels or used an S, a*, b* feature set. Copyright © 2016 Japan Prosthodontic Society. Published by Elsevier Ltd. All rights reserved.

  8. The Use of the International Classification of Functioning, Disability and Health, Version for Children and Youth (ICF-CY), in Portuguese Special Education Assessment and Eligibility Procedures: The Professionals' Perceptions

    ERIC Educational Resources Information Center

    Sanches-Ferreira, Manuela; Silveira-Maia, Mónica; Alves, Sílvia

    2014-01-01

    Portugal was the first country decreeing the mandatory use of the International Classification of Functioning, Disability and Health: Child and Youth (ICF-CY) framework for guiding special education assessment process and to base eligibility decision-making on students' functioning profiles--in contrast with traditional approaches centred on…

  9. Updating Classifications of Ceramic Dental Materials: A Guide to Material Selection.

    PubMed

    McLaren, Edward A; Figueira, Johan

    2015-06-01

    The indications for and composition of today's dental ceramic materials serve as the basis for determining the appropriate class of ceramics to use for a given case. By understanding the classifications, composition, and characteristics of the latest all-ceramic materials, which are presented in this article in order of most to least conservative, dentists and laboratory technicians can best determine the ideal material for a particular treatment.

  10. Java Web Start based software for automated quantitative nuclear analysis of prostate cancer and benign prostate hyperplasia.

    PubMed

    Singh, Swaroop S; Kim, Desok; Mohler, James L

    2005-05-11

    Androgen acts via androgen receptor (AR) and accurate measurement of the levels of AR protein expression is critical for prostate research. The expression of AR in paired specimens of benign prostate and prostate cancer from 20 African and 20 Caucasian Americans was compared to demonstrate an application of this system. A set of 200 immunopositive and 200 immunonegative nuclei were collected from the images using a macro developed in Image Pro Plus. Linear Discriminant and Logistic Regression analyses were performed on the data to generate classification coefficients. Classification coefficients render the automated image analysis software independent of the type of immunostaining or image acquisition system used. The image analysis software performs local segmentation and uses nuclear shape and size to detect prostatic epithelial nuclei. AR expression is described by (a) percentage of immunopositive nuclei; (b) percentage of immunopositive nuclear area; and (c) intensity of AR expression among immunopositive nuclei or areas. The percent positive nuclei and percent nuclear area were similar by race in both benign prostate hyperplasia and prostate cancer. In prostate cancer epithelial nuclei, African Americans exhibited 38% higher levels of AR immunostaining than Caucasian Americans (two sided Student's t-tests; P < 0.05). Intensity of AR immunostaining was similar between races in benign prostate. The differences measured in the intensity of AR expression in prostate cancer were consistent with previous studies. Classification coefficients are required due to non-standardized immunostaining and image collection methods across medical institutions and research laboratories and helps customize the software for the specimen under study. The availability of a free, automated system creates new opportunities for testing, evaluation and use of this image analysis system by many research groups who study nuclear protein expression.

  11. Clinical Assessment of the Infant and Child Following Perinatal Brachial Plexus Injury

    PubMed Central

    Duff, Susan V.; DeMatteo, Carol

    2015-01-01

    STUDY DESIGN Literature review INTRODUCTION After perinatal brachial plexus injury (PBPI), clinicians play an important role in injury classification as well as the assessment of recovery and secondary conditions. Early assessment guides the initial plan of care and influences follow-up and long-term outcome. PURPOSE To review methods used to assess, classify and monitor the extent and influence of PBPI with an emphasis on guidelines for clinicians. METHODS We use The International Classification of Functioning, Disability, and Health (ICF) model to provide a guide to assessment after PBPI for rehabilitation clinicians. DISCUSSION With information gained from targeted assessments, clinicians can design interventions to increase the opportunities infants and children have for optimal recovery and to attain skills that allow participation in areas of interest. PMID:25840493

  12. Applying the International Classification of Functioning, Disability and Health to guide home health care services planning and delivery in Thailand.

    PubMed

    Pimdee, Atipong; Nualnetr, Nomjit

    2017-01-01

    Home health care is an essential service for home-bound patients in Thailand. In this action research study, we used the International Classification of Functioning, Disability and Health (ICF) framework to modify home health care services provided by a university hospital. Staff responsible for delivering the services (physical therapist, nurses, and Thai traditional medicine practitioners) participated in the development of an ICF-based assessment tool and home health care service procedure. After an 8-month trial of implementing these changes, professional satisfaction and empowerment were high among the home health care team members. Patients and their caregivers were also satisfied with the services. In conclusion, the ICF is an effective means of guiding home health care.

  13. Selective Immunophenotyping for Diagnosis of B-cell Neoplasms: Immunohistochemistry and Flow Cytometry Strategies and Results

    PubMed Central

    Boyd, Scott D.; Natkunam, Yasodha; Allen, John R.; Warnke, Roger A.

    2012-01-01

    Determining the immunophenotype of hematologic malignancies is now an indispensible part of diagnostic classification, and can help to guide therapy, or to predict clinical outcome. Diagnostic workup should be guided by morphologic findings and evaluate clinically important markers, but ideally should avoid the use of overly-broad panels of immunostains that can reveal incidental findings of uncertain significance and give rise to increased costs. Here, we outline our approach to diagnosis of B cell neoplasms, combining histologic and clinical data with tailored panels of immunophenotyping reagents, in the context of the 2008 World Health Organization classification. We present data from cases seen at our institution from 2004-8 using this approach, to provide a practical reference for findings seen in daily diagnostic practice. PMID:22820658

  14. Field Guide to the Plant Community Types of Voyageurs National Park

    USGS Publications Warehouse

    Faber-Langendoen, Don; Aaseng, Norman; Hop, Kevin; Lew-Smith, Michael

    2007-01-01

    INTRODUCTION The objective of the U.S. Geological Survey-National Park Service Vegetation Mapping Program is to classify, describe, and map vegetation for most of the park units within the National Park Service (NPS). The program was created in response to the NPS Natural Resources Inventory and Monitoring Guidelines issued in 1992. Products for each park include digital files of the vegetation map and field data, keys and descriptions to the plant communities, reports, metadata, map accuracy verification summaries, and aerial photographs. Interagency teams work in each park and, following standardized mapping and field sampling protocols, develop products and vegetation classification standards that document the various vegetation types found in a given park. The use of a standard national vegetation classification system and mapping protocol facilitate effective resource stewardship by ensuring compatibility and widespread use of the information throughout the NPS as well as by other Federal and state agencies. These vegetation classifications and maps and associated information support a wide variety of resource assessment, park management, and planning needs, and provide a structure for framing and answering critical scientific questions about plant communities and their relation to environmental processes across the landscape. This field guide is intended to make the classification accessible to park visitors and researchers at Voyageurs National Park, allowing them to identify any stand of natural vegetation and showing how the classification can be used in conjunction with the vegetation map (Hop and others, 2001).

  15. Accurate Detection of Dysmorphic Nuclei Using Dynamic Programming and Supervised Classification.

    PubMed

    Verschuuren, Marlies; De Vylder, Jonas; Catrysse, Hannes; Robijns, Joke; Philips, Wilfried; De Vos, Winnok H

    2017-01-01

    A vast array of pathologies is typified by the presence of nuclei with an abnormal morphology. Dysmorphic nuclear phenotypes feature dramatic size changes or foldings, but also entail much subtler deviations such as nuclear protrusions called blebs. Due to their unpredictable size, shape and intensity, dysmorphic nuclei are often not accurately detected in standard image analysis routines. To enable accurate detection of dysmorphic nuclei in confocal and widefield fluorescence microscopy images, we have developed an automated segmentation algorithm, called Blebbed Nuclei Detector (BleND), which relies on two-pass thresholding for initial nuclear contour detection, and an optimal path finding algorithm, based on dynamic programming, for refining these contours. Using a robust error metric, we show that our method matches manual segmentation in terms of precision and outperforms state-of-the-art nuclear segmentation methods. Its high performance allowed for building and integrating a robust classifier that recognizes dysmorphic nuclei with an accuracy above 95%. The combined segmentation-classification routine is bound to facilitate nucleus-based diagnostics and enable real-time recognition of dysmorphic nuclei in intelligent microscopy workflows.

  16. Accurate Detection of Dysmorphic Nuclei Using Dynamic Programming and Supervised Classification

    PubMed Central

    Verschuuren, Marlies; De Vylder, Jonas; Catrysse, Hannes; Robijns, Joke; Philips, Wilfried

    2017-01-01

    A vast array of pathologies is typified by the presence of nuclei with an abnormal morphology. Dysmorphic nuclear phenotypes feature dramatic size changes or foldings, but also entail much subtler deviations such as nuclear protrusions called blebs. Due to their unpredictable size, shape and intensity, dysmorphic nuclei are often not accurately detected in standard image analysis routines. To enable accurate detection of dysmorphic nuclei in confocal and widefield fluorescence microscopy images, we have developed an automated segmentation algorithm, called Blebbed Nuclei Detector (BleND), which relies on two-pass thresholding for initial nuclear contour detection, and an optimal path finding algorithm, based on dynamic programming, for refining these contours. Using a robust error metric, we show that our method matches manual segmentation in terms of precision and outperforms state-of-the-art nuclear segmentation methods. Its high performance allowed for building and integrating a robust classifier that recognizes dysmorphic nuclei with an accuracy above 95%. The combined segmentation-classification routine is bound to facilitate nucleus-based diagnostics and enable real-time recognition of dysmorphic nuclei in intelligent microscopy workflows. PMID:28125723

  17. Interplay of biopharmaceutics, biopharmaceutics drug disposition and salivary excretion classification systems

    PubMed Central

    Idkaidek, Nasir M.

    2013-01-01

    The aim of this commentary is to investigate the interplay of Biopharmaceutics Classification System (BCS), Biopharmaceutics Drug Disposition Classification System (BDDCS) and Salivary Excretion Classification System (SECS). BCS first classified drugs based on permeability and solubility for the purpose of predicting oral drug absorption. Then BDDCS linked permeability with hepatic metabolism and classified drugs based on metabolism and solubility for the purpose of predicting oral drug disposition. On the other hand, SECS classified drugs based on permeability and protein binding for the purpose of predicting the salivary excretion of drugs. The role of metabolism, rather than permeability, on salivary excretion is investigated and the results are not in agreement with BDDCS. Conclusion The proposed Salivary Excretion Classification System (SECS) can be used as a guide for drug salivary excretion based on permeability (not metabolism) and protein binding. PMID:24493977

  18. Transporter taxonomy - a comparison of different transport protein classification schemes.

    PubMed

    Viereck, Michael; Gaulton, Anna; Digles, Daniela; Ecker, Gerhard F

    2014-06-01

    Currently, there are more than 800 well characterized human membrane transport proteins (including channels and transporters) and there are estimates that about 10% (approx. 2000) of all human genes are related to transport. Membrane transport proteins are of interest as potential drug targets, for drug delivery, and as a cause of side effects and drug–drug interactions. In light of the development of Open PHACTS, which provides an open pharmacological space, we analyzed selected membrane transport protein classification schemes (Transporter Classification Database, ChEMBL, IUPHAR/BPS Guide to Pharmacology, and Gene Ontology) for their ability to serve as a basis for pharmacology driven protein classification. A comparison of these membrane transport protein classification schemes by using a set of clinically relevant transporters as use-case reveals the strengths and weaknesses of the different taxonomy approaches.

  19. Congenital Differences of the Upper Extremity: Classification and Treatment Principles

    PubMed Central

    2011-01-01

    For hand surgeons, the treatment of children with congenital differences of the upper extremity is challenging because of the diverse spectrum of conditions encountered, but the task is also rewarding because it provides surgeons with the opportunity to impact a child's growth and development. An ideal classification of congenital differences of the upper extremity would reflect the full spectrum of morphologic abnormalities and encompass etiology, a guide to treatment, and provide prognoses. In this report, I review current classification systems and discuss their contradictions and limitations. In addition, I present a modified classification system and provide treatment principles. As our understanding of the etiology of congenital differences of the upper extremity increases and as experience of treating difficult cases accumulates, even an ideal classification system and optimal treatment strategies will undoubtedly continue to evolve. PMID:21909463

  20. Computer-aided classification of optical images for diagnosis of osteoarthritis in the finger joints.

    PubMed

    Zhang, Jiang; Wang, James Z; Yuan, Zhen; Sobel, Eric S; Jiang, Huabei

    2011-01-01

    This study presents a computer-aided classification method to distinguish osteoarthritis finger joints from healthy ones based on the functional images captured by x-ray guided diffuse optical tomography. Three imaging features, joint space width, optical absorption, and scattering coefficients, are employed to train a Least Squares Support Vector Machine (LS-SVM) classifier for osteoarthritis classification. The 10-fold validation results show that all osteoarthritis joints are clearly identified and all healthy joints are ruled out by the LS-SVM classifier. The best sensitivity, specificity, and overall accuracy of the classification by experienced technicians based on manual calculation of optical properties and visual examination of optical images are only 85%, 93%, and 90%, respectively. Therefore, our LS-SVM based computer-aided classification is a considerably improved method for osteoarthritis diagnosis.

  1. Nuclear Engine System Simulation (NESS). Version 2.0: Program user's guide

    NASA Technical Reports Server (NTRS)

    Pelaccio, Dennis G.; Scheil, Christine M.; Petrosky, Lyman

    1993-01-01

    This Program User's Guide discusses the Nuclear Thermal Propulsion (NTP) engine system design features and capabilities modeled in the Nuclear Engine System Simulation (NESS): Version 2.0 program (referred to as NESS throughout the remainder of this document), as well as its operation. NESS was upgraded to include many new modeling capabilities not available in the original version delivered to NASA LeRC in Dec. 1991, NESS's new features include the following: (1) an improved input format; (2) an advanced solid-core NERVA-type reactor system model (ENABLER 2); (3) a bleed-cycle engine system option; (4) an axial-turbopump design option; (5) an automated pump-out turbopump assembly sizing option; (6) an off-design gas generator engine cycle design option; (7) updated hydrogen properties; (8) an improved output format; and (9) personal computer operation capability. Sample design cases are presented in the user's guide that demonstrate many of the new features associated with this upgraded version of NESS, as well as design modeling features associated with the original version of NESS.

  2. Remote sensing change detection methods to track deforestation and growth in threatened rainforests in Madre de Dios, Peru

    USGS Publications Warehouse

    Shermeyer, Jacob S.; Haack, Barry N.

    2015-01-01

    Two forestry-change detection methods are described, compared, and contrasted for estimating deforestation and growth in threatened forests in southern Peru from 2000 to 2010. The methods used in this study rely on freely available data, including atmospherically corrected Landsat 5 Thematic Mapper and Moderate Resolution Imaging Spectroradiometer (MODIS) vegetation continuous fields (VCF). The two methods include a conventional supervised signature extraction method and a unique self-calibrating method called MODIS VCF guided forest/nonforest (FNF) masking. The process chain for each of these methods includes a threshold classification of MODIS VCF, training data or signature extraction, signature evaluation, k-nearest neighbor classification, analyst-guided reclassification, and postclassification image differencing to generate forest change maps. Comparisons of all methods were based on an accuracy assessment using 500 validation pixels. Results of this accuracy assessment indicate that FNF masking had a 5% higher overall accuracy and was superior to conventional supervised classification when estimating forest change. Both methods succeeded in classifying persistently forested and nonforested areas, and both had limitations when classifying forest change.

  3. 10 CFR Appendix I to Part 50 - Numerical Guides for Design Objectives and Limiting Conditions for Operation To Meet the...

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... in Light-Water-Cooled Nuclear Power Reactor Effluents I Appendix I to Part 50 Energy NUCLEAR... Criterion “As Low as is Reasonably Achievable” for Radioactive Material in Light-Water-Cooled Nuclear Power... light-water-cooled nuclear power reactors licensed under 10 CFR part 50 or part 52 of this chapter. The...

  4. 10 CFR Appendix I to Part 50 - Numerical Guides for Design Objectives and Limiting Conditions for Operation To Meet the...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... in Light-Water-Cooled Nuclear Power Reactor Effluents I Appendix I to Part 50 Energy NUCLEAR... Criterion “As Low as is Reasonably Achievable” for Radioactive Material in Light-Water-Cooled Nuclear Power... light-water-cooled nuclear power reactors licensed under 10 CFR part 50 or part 52 of this chapter. The...

  5. 10 CFR Appendix I to Part 50 - Numerical Guides for Design Objectives and Limiting Conditions for Operation To Meet the...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... in Light-Water-Cooled Nuclear Power Reactor Effluents I Appendix I to Part 50 Energy NUCLEAR... Criterion “As Low as is Reasonably Achievable” for Radioactive Material in Light-Water-Cooled Nuclear Power... light-water-cooled nuclear power reactors licensed under 10 CFR part 50 or part 52 of this chapter. The...

  6. Differentiation of Crataegus spp. guided by nuclear magnetic resonance spectrometry with chemometric analyses.

    PubMed

    Lund, Jensen A; Brown, Paula N; Shipley, Paul R

    2017-09-01

    For compliance with US Current Good Manufacturing Practice regulations for dietary supplements, manufacturers must provide identity of source plant material. Despite the popularity of hawthorn as a dietary supplement, relatively little is known about the comparative phytochemistry of different hawthorn species, and in particular North American hawthorns. The combination of NMR spectrometry with chemometric analyses offers an innovative approach to differentiating hawthorn species and exploring the phytochemistry. Two European and two North American species, harvested from a farm trial in late summer 2008, were analyzed by standard 1D 1 H and J-resolved (JRES) experiments. The data were preprocessed and modelled by principal component analysis (PCA). A supervised model was then generated by partial least squares-discriminant analysis (PLS-DA) for classification and evaluated by cross validation. Supervised random forests models were constructed from the dataset to explore the potential of machine learning for identification of unique patterns across species. 1D 1 H NMR data yielded increased differentiation over the JRES data. The random forests results correlated with PLS-DA results and outperformed PLS-DA in classification accuracy. In all of these analyses differentiation of the Crataegus spp. was best achieved by focusing on the NMR spectral region that contains signals unique to plant phenolic compounds. Identification of potentially significant metabolites for differentiation between species was approached using univariate techniques including significance analysis of microarrays and Kruskall-Wallis tests. Copyright © 2017 Elsevier Ltd. All rights reserved.

  7. Supporting breast-feeding when a woman is homeless.

    PubMed

    Crespo-Fierro, Michele; Lunney, Margaret

    2011-01-01

    This case study demonstrates use of standardized nursing languages in the care of new mothers in community settings. The author collected data from clinical practice as an instructor in a baccalaureate nursing program and from the research literature. The appropriate nursing diagnoses, outcomes, and interventions were identified in partnership with the new mother. This case shows that NANDA International (NANDA-I), the Nursing Outcomes Classification (NOC), and the Nursing Interventions Classification (NIC) are useful to direct nursing care in community settings. When teaching nursing students in a baccalaureate program, nurse faculty can use NANDA-I, NOC, and NIC classifications to guide the growing practice of nursing students in community settings. © 2011, The Authors. International Journal of Nursing Terminologies and Classifications © 2011, NANDA International.

  8. 76 FR 14107 - Notice of Issuance of Regulatory Guide

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-15

    ... INFORMATION: I. Introduction The U.S. Nuclear Regulatory Commission (NRC or Commission) is issuing a revision... Branch, Division of Engineering, Office of Nuclear Regulatory Research. [FR Doc. 2011-5967 Filed 3-14-11...

  9. Why Nuclear Education? A Sourcebook for Educators and Parents.

    ERIC Educational Resources Information Center

    Alexander, Susan

    This guide is designed as a resource for individuals and groups who are considering why and how to implement teaching about nuclear issues in the classroom. Section I presents some questions frequently asked about nuclear education and responses based upon the experience and research of Educators for Social Responsibility. Section II highlights…

  10. 77 FR 50722 - Software Unit Testing for Digital Computer Software Used in Safety Systems of Nuclear Power Plants

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-22

    ... NUCLEAR REGULATORY COMMISSION [NRC-2012-0195] Software Unit Testing for Digital Computer Software...) is issuing for public comment draft regulatory guide (DG), DG-1208, ``Software Unit Testing for Digital Computer Software used in Safety Systems of Nuclear Power Plants.'' The DG-1208 is proposed...

  11. 78 FR 47011 - Software Unit Testing for Digital Computer Software Used in Safety Systems of Nuclear Power Plants

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-02

    ... NUCLEAR REGULATORY COMMISSION [NRC-2012-0195] Software Unit Testing for Digital Computer Software... revised regulatory guide (RG), revision 1 of RG 1.171, ``Software Unit Testing for Digital Computer Software Used in Safety Systems of Nuclear Power Plants.'' This RG endorses American National Standards...

  12. 78 FR 31614 - Implementation of Regulatory Guide 1.221 on Design-Basis Hurricane and Hurricane Missiles

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-24

    ... for Nuclear Power Plants,'' in support of NRC reviews of early site permit (ESP), standard design... NUREG-0800, ``Standard Review Plan for the Review of Safety Analysis Reports for Nuclear Power Plants... License Applications for Nuclear Power Plants, (LWR Edition)'' (ML070630003) In addition, this ISG...

  13. UNESCO Chemistry Teaching Project in Asia: Experiments on Nuclear Science.

    ERIC Educational Resources Information Center

    Dhabanandana, Salag

    This teacher's guide on nuclear science is divided into two parts. The first part is a discussion of some of the concepts in nuclear chemistry including radioactivity, types of disintegration, radioactive decay and growth, and tracer techniques. The relevant experiments involving the use of radioisotopes are presented in the second part. The…

  14. 76 FR 24062 - Florida Power and Light Company, St. Lucie, Unit Nos. 1 and 2; Exemption

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-29

    ... (d) is again required. Regulatory Guide 5.73, Fatigue Management for Nuclear Power Plant Personnel, endorses the Nuclear Energy Institute (NEI) report NEI 06- 11, revision 1, ``Managing Personnel Fatigue at Nuclear Power Plants,'' with certain clarifications, additions and exceptions. The NRC staff has endorsed...

  15. Understanding Nuclear Weapons and Arms Control: A Guide to the Issues. Instructor's Manual.

    ERIC Educational Resources Information Center

    Zahka, William J.; Mayers, Teena Karsa

    Intended for teachers of secondary and college level students, this instructor's guide presents an overview of materials covered in the student text, followed by four categories of examination questions and teaching aids. The guide reflects the format of the student text and is divided into four sections. A brief description is provided of each…

  16. Lauren classification and individualized chemotherapy in gastric cancer.

    PubMed

    Ma, Junli; Shen, Hong; Kapesa, Linda; Zeng, Shan

    2016-05-01

    Gastric cancer is one of the most common malignancies worldwide. During the last 50 years, the histological classification of gastric carcinoma has been largely based on Lauren's criteria, in which gastric cancer is classified into two major histological subtypes, namely intestinal type and diffuse type adenocarcinoma. This classification was introduced in 1965, and remains currently widely accepted and employed, since it constitutes a simple and robust classification approach. The two histological subtypes of gastric cancer proposed by the Lauren classification exhibit a number of distinct clinical and molecular characteristics, including histogenesis, cell differentiation, epidemiology, etiology, carcinogenesis, biological behaviors and prognosis. Gastric cancer exhibits varied sensitivity to chemotherapy drugs and significant heterogeneity; therefore, the disease may be a target for individualized therapy. The Lauren classification may provide the basis for individualized treatment for advanced gastric cancer, which is increasingly gaining attention in the scientific field. However, few studies have investigated individualized treatment that is guided by pathological classification. The aim of the current review is to analyze the two major histological subtypes of gastric cancer, as proposed by the Lauren classification, and to discuss the implications of this for personalized chemotherapy.

  17. A new classification system for congenital laryngeal cysts.

    PubMed

    Forte, Vito; Fuoco, Gabriel; James, Adrian

    2004-06-01

    A new classification system for congenital laryngeal cysts based on the extent of the cyst and on the embryologic tissue of origin is proposed. Retrospective chart review. The charts of 20 patients with either congenital or acquired laryngeal cysts that were treated surgically between 1987 and 2002 at the Hospital for Sick Children, Toronto were retrospectively reviewed. Clinical presentation, radiologic findings, surgical management, histopathology, and outcome were recorded. A new classification system is proposed to better appreciate the origin of these cysts and to guide in their successful surgical management. Fourteen of the supraglottic and subglottic simple mucous retention cysts posed no diagnostic or therapeutic challenge and were treated successfully by a single endoscopic excision or marsupialization. The remaining six patients with congenital cysts in the study were deemed more complex, and all required open surgical procedures for cure. On the basis of the analysis of the data of these patients, a new classification of congenital laryngeal cysts is proposed. Type I cysts are confined to the larynx, the cyst wall composed of endodermal elements only, and can be managed endoscopically. Type II cysts extend beyond the confines of the larynx and require an external approach. The Type II cysts are further subclassified histologically on the basis of the embryologic tissue of origin: IIa, composed of endoderm only and IIb, containing endodermal and mesodermal elements (epithelium and cartilage) in the wall of the cyst. A new classification system for congenital laryngeal cysts is proposed on the basis of the extent of the cyst and the embryologic tissue of origin. This classification can help guide the surgeon with initial management and help us better understand the origin of these cysts.

  18. Effect of Process-Oriented Guided-Inquiry Learning on Non-majors Biology Students' Understanding of Biological Classification

    NASA Astrophysics Data System (ADS)

    Wozniak, Breann M.

    The purpose of this study was to examine the effect of process-oriented guided-inquiry learning (POGIL) on non-majors college biology students' understanding of biological classification. This study addressed an area of science instruction, POGIL in the non-majors college biology laboratory, which has yet to be qualitatively and quantitatively researched. A concurrent triangulation mixed methods approach was used. Students' understanding of biological classification was measured in two areas: scores on pre and posttests (consisting of 11 multiple choice questions), and conceptions of classification as elicited in pre and post interviews and instructor reflections. Participants were Minnesota State University, Mankato students enrolled in BIOL 100 Summer Session. One section was taught with the traditional curriculum (n = 6) and the other section in the POGIL curriculum (n = 10) developed by the researcher. Three students from each section were selected to take part in pre and post interviews. There were no significant differences within each teaching method (p < .05). There was a tendency of difference in the means. The POGIL group may have scored higher on the posttest (M = 8.830 +/- .477 vs. M = 7.330 +/- .330; z =-1.729, p = .084) and the traditional group may have scored higher on the pretest than the posttest (M = 8.333 +/- .333 vs M = 7.333 +/- .333; z = -1.650 , p = .099). Two themes emerged after the interviews and instructor reflections: 1) After instruction students had a more extensive understanding of classification in three areas: vocabulary terms, physical characteristics, and types of evidence used to classify. Both groups extended their understanding, but only POGIL students could explain how molecular evidence is used in classification. 2) The challenges preventing students from understanding classification were: familiar animal categories and aquatic habitats, unfamiliar organisms, combining and subdividing initial groupings, and the hierarchical nature of classification. The POGIL students were the only group to surpass these challenges after the teaching intervention. This study shows that POGIL is an effective technique at eliciting students' misconceptions, and addressing these misconceptions, leading to an increase in student understanding of biological classification.

  19. Compartiendo la Ciencia con los Ninos: Una Guia para los Padres (Sharing Science with Children: A Guide for Parents).

    ERIC Educational Resources Information Center

    North Carolina Museum of Life and Science, Durham.

    This guide offers Spanish-speaking parents ways in which they can help their children learn about science at home and in the community. Science is a way of looking at the world. It uses everyday techniques such as observation and classification to give us information about things and how they work. Advice to parents that want to support their…

  20. Visualizing the molecular sociology at the HeLa cell nuclear periphery.

    PubMed

    Mahamid, Julia; Pfeffer, Stefan; Schaffer, Miroslava; Villa, Elizabeth; Danev, Radostin; Cuellar, Luis Kuhn; Förster, Friedrich; Hyman, Anthony A; Plitzko, Jürgen M; Baumeister, Wolfgang

    2016-02-26

    The molecular organization of eukaryotic nuclear volumes remains largely unexplored. Here we combined recent developments in cryo-electron tomography (cryo-ET) to produce three-dimensional snapshots of the HeLa cell nuclear periphery. Subtomogram averaging and classification of ribosomes revealed the native structure and organization of the cytoplasmic translation machinery. Analysis of a large dynamic structure-the nuclear pore complex-revealed variations detectable at the level of individual complexes. Cryo-ET was used to visualize previously elusive structures, such as nucleosome chains and the filaments of the nuclear lamina, in situ. Elucidation of the lamina structure provides insight into its contribution to metazoan nuclear stiffness. Copyright © 2016, American Association for the Advancement of Science.

  1. Wildfire Prevention Strategies.

    ERIC Educational Resources Information Center

    National Wildlife Coordinating Group, Boise, ID.

    This document provides information and guidance on wildfire prevention strategies. Chapters include: (1) "Introduction"; (2) "How to Use this Guide"; (3) "Fire Cause Classification"; (4) "Relative Effectiveness"; (5) "Degree of Difficulty"; (6) "Intervention Techniques"; (7)…

  2. Limitations and implications of stream classification

    USGS Publications Warehouse

    Juracek, K.E.; Fitzpatrick, F.A.

    2003-01-01

    Stream classifications that are based on channel form, such as the Rosgen Level II classification, are useful tools for the physical description and grouping of streams and for providing a means of communication for stream studies involving scientists and (or) managers with different backgrounds. The Level II classification also is used as a tool to assess stream stability, infer geomorphic processes, predict future geomorphic response, and guide stream restoration or rehabilitation activities. The use of the Level II classification for these additional purposes is evaluated in this paper. Several examples are described to illustrate the limitations and management implications of the Level II classification. Limitations include: (1) time dependence, (2) uncertain applicability across physical environments, (3) difficulty in identification of a true equilibrium condition, (4) potential for incorrect determination of bankfull elevation, and (5) uncertain process significance of classification criteria. Implications of using stream classifications based on channel form, such as Rosgen's, include: (1) acceptance of the limitations, (2) acceptance of the risk of classifying streams incorrectly, and (3) classification results may be used inappropriately. It is concluded that use of the Level II classification for purposes beyond description and communication is not appropriate. Research needs are identified that, if addressed, may help improve the usefulness of the Level II classification.

  3. Operation Tomodachi Registry: Radiation Data Compendium

    DTIC Science & Technology

    2013-08-01

    affiliated individuals were potentially exposed to radiation as a result of the Fukushima Daiichi Nuclear Power Station radiological releases that followed...Radiation Dose, Department of Defense, Japan, Fukushima , Earthquake, Tsunami, Environmental Data, Radiation Data 16. SECURITY CLASSIFICATION OF: 17...materials from the Fukushima Daiichi Nuclear Power Station (FDNPS), the Department of Defense (DOD) responded by providing humanitarian assistance

  4. Phylogeny of the cycads based on multiple single copy nuclear genes: congruence of concatenation and species tree inference methods

    USDA-ARS?s Scientific Manuscript database

    Despite a recent new classification, a stable tree of life for the cycads has been elusive, particularly regarding resolution of Bowenia, Stangeria and Dioon. In this study we apply five single copy nuclear genes (SCNGs) to the phylogeny of the order Cycadales. We specifically aim to evaluate seve...

  5. 48 CFR 952.204-76 - Conditional payment of fee or profit-safeguarding restricted data and other classified information.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... compartmented information (SCI), or high risk nuclear weapons-related data. (ii) Contractor actions that result... as SCI, or high risk nuclear weapons-related data. (iii) Failure to promptly report the loss... Secret, any classification level of information in a SAP, information identified as SCI, or high risk...

  6. Deep learning application: rubbish classification with aid of an android device

    NASA Astrophysics Data System (ADS)

    Liu, Sijiang; Jiang, Bo; Zhan, Jie

    2017-06-01

    Deep learning is a very hot topic currently in pattern recognition and artificial intelligence researches. Aiming at the practical problem that people usually don't know correct classifications some rubbish should belong to, based on the powerful image classification ability of the deep learning method, we have designed a prototype system to help users to classify kinds of rubbish. Firstly the CaffeNet Model was adopted for our classification network training on the ImageNet dataset, and the trained network was deployed on a web server. Secondly an android app was developed for users to capture images of unclassified rubbish, upload images to the web server for analyzing backstage and retrieve the feedback, so that users can obtain the classification guide by an android device conveniently. Tests on our prototype system of rubbish classification show that: an image of one single type of rubbish with origin shape can be better used to judge its classification, while an image containing kinds of rubbish or rubbish with changed shape may fail to help users to decide rubbish's classification. However, the system still shows promising auxiliary function for rubbish classification if the network training strategy can be optimized further.

  7. Security management techniques and evaluative checklists for security force effectiveness. Technical report (final) Sep 80-Jul 81

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Schurman, D.L.; Datesman, G.H. Jr; Truitt, J.O.

    The report presents a system for evaluating and correcting deficiencies in security-force effectiveness in licensed nuclear facilities. There are four checklists which security managers can copy directly, or can use as guidelines for developing their own checklists. The checklists are keyed to corrective-action guides found in the body of the report. In addition to the corrective-action guides, the report gives background information on the nature of security systems and discussions of various special problems of the licensed nuclear industry.

  8. 21 CFR 876.5365 - Esophageal dilator.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... and weighted with mercury or a metal olive-shaped weight that slides on a guide, such as a string or... esophageal or gastrointestinal bougies and the esophageal dilator (metal olive). (b) Classification. Class II...

  9. 32 CFR 1700.8 - Action on the request.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... recommendations, ODNI staff shall be guided by the procedures specified in § 1700.10 regarding confidential...) When the withholding is based in whole or in part on a security classification, the explanation shall...

  10. 32 CFR 1700.8 - Action on the request.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... recommendations, ODNI staff shall be guided by the procedures specified in § 1700.10 regarding confidential...) When the withholding is based in whole or in part on a security classification, the explanation shall...

  11. The Use and Abuse of Diagnostic/Classification Criteria

    PubMed Central

    June, Rayford R.; Aggarwal, Rohit

    2015-01-01

    In rheumatic diseases, classification criteria have been developed to identify well-defined homogenous cohorts for clinical research. Although, they are commonly used in clinical practice, their use may not be appropriate for routine diagnostic clinical care. Classification criteria are being revised with improved methodology and further understanding of disease pathophysiology, but still may not encompass all unique clinical situations to be applied for diagnosis of heterogeneous, rare, evolving rheumatic diseases. Diagnostic criteria development is challenging primarily due to difficulty for universal application given significant differences in prevalence of rheumatic diseases based on geographical area and clinic settings. Despite these shortcomings, the clinician can still use classification criteria for understanding the disease as well as a guide for diagnosis with a few caveats. We present the limits of current classification criteria, describe their use and abuse in clinical practice, and how they should be used with caution when applied in clinics. PMID:26096094

  12. Watermelons Not War! A Support Book for Parenting in the Nuclear Age.

    ERIC Educational Resources Information Center

    Cloud, Kate; And Others

    The Nuclear Education Project (NEP), a group of five women concerned about parenting in a nuclear age, developed this guide to help parents and others develop a sense of hope and promote a greater involvement in the democratic political process. Chapter I, "The Heart of the Matter," presents sections on answering possible questions children might…

  13. 77 FR 40921 - Communication With Transport Vehicles

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-11

    ... NUCLEAR REGULATORY COMMISSION [NRC-2012-0163] Communication With Transport Vehicles AGENCY... Transport Vehicles,'' published in May 1975. The guide is being withdrawn because it is outdated due to... withdrawing Regulatory Guide 5.32, revision 1, ``Communication with Transport Vehicles,'' published in May...

  14. 76 FR 24538 - Draft Regulatory Guide: Issuance, Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-02

    ... Guide, DG-1264, ``Thermal Overload Protection for Electric Motors On Motor- Operated Valves.'' FOR FURTHER INFORMATION CONTACT: Darrell Murdock, U.S. Nuclear Regulatory Commission, Washington, DC 20555-0001, telephone: 301-251- 7629 or e-mail [email protected] . SUPPLEMENTARY INFORMATION: I...

  15. Quantitative evaluation of variations in rule-based classifications of land cover in urban neighbourhoods using WorldView-2 imagery.

    PubMed

    Belgiu, Mariana; Dr Guţ, Lucian; Strobl, Josef

    2014-01-01

    The increasing availability of high resolution imagery has triggered the need for automated image analysis techniques, with reduced human intervention and reproducible analysis procedures. The knowledge gained in the past might be of use to achieving this goal, if systematically organized into libraries which would guide the image analysis procedure. In this study we aimed at evaluating the variability of digital classifications carried out by three experts who were all assigned the same interpretation task. Besides the three classifications performed by independent operators, we developed an additional rule-based classification that relied on the image classifications best practices found in the literature, and used it as a surrogate for libraries of object characteristics. The results showed statistically significant differences among all operators who classified the same reference imagery. The classifications carried out by the experts achieved satisfactory results when transferred to another area for extracting the same classes of interest, without modification of the developed rules.

  16. Quantitative evaluation of variations in rule-based classifications of land cover in urban neighbourhoods using WorldView-2 imagery

    PubMed Central

    Belgiu, Mariana; Drǎguţ, Lucian; Strobl, Josef

    2014-01-01

    The increasing availability of high resolution imagery has triggered the need for automated image analysis techniques, with reduced human intervention and reproducible analysis procedures. The knowledge gained in the past might be of use to achieving this goal, if systematically organized into libraries which would guide the image analysis procedure. In this study we aimed at evaluating the variability of digital classifications carried out by three experts who were all assigned the same interpretation task. Besides the three classifications performed by independent operators, we developed an additional rule-based classification that relied on the image classifications best practices found in the literature, and used it as a surrogate for libraries of object characteristics. The results showed statistically significant differences among all operators who classified the same reference imagery. The classifications carried out by the experts achieved satisfactory results when transferred to another area for extracting the same classes of interest, without modification of the developed rules. PMID:24623959

  17. Quantitative evaluation of variations in rule-based classifications of land cover in urban neighbourhoods using WorldView-2 imagery

    NASA Astrophysics Data System (ADS)

    Belgiu, Mariana; ǎguţ, Lucian, , Dr; Strobl, Josef

    2014-01-01

    The increasing availability of high resolution imagery has triggered the need for automated image analysis techniques, with reduced human intervention and reproducible analysis procedures. The knowledge gained in the past might be of use to achieving this goal, if systematically organized into libraries which would guide the image analysis procedure. In this study we aimed at evaluating the variability of digital classifications carried out by three experts who were all assigned the same interpretation task. Besides the three classifications performed by independent operators, we developed an additional rule-based classification that relied on the image classifications best practices found in the literature, and used it as a surrogate for libraries of object characteristics. The results showed statistically significant differences among all operators who classified the same reference imagery. The classifications carried out by the experts achieved satisfactory results when transferred to another area for extracting the same classes of interest, without modification of the developed rules.

  18. 77 FR 3514 - Protection Against Turbine Missiles

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-24

    ... NUCLEAR REGULATORY COMMISSION [NRC-2009-0481] Protection Against Turbine Missiles AGENCY: Nuclear... (NRC or Commission) is issuing a revision to Regulatory Guide 1.115, ``Protection Against Turbine... structures, systems, and components against missiles resulting from turbine failure by the appropriate...

  19. 77 FR 14047 - Guidance for Decommissioning Planning During Operations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-08

    ...)-4014, ``Decommissioning Planning During Operations.'' This action is necessary to correct the NRC's... NUCLEAR REGULATORY COMMISSION [NRC-2011-0286] Guidance for Decommissioning Planning During Operations AGENCY: Nuclear Regulatory Commission. ACTION: Draft regulatory guide; correction. SUMMARY: The U...

  20. Surgical management of morbidity due to lymphatic filariasis: the usefulness of a standardized international clinical classification of hydroceles.

    PubMed

    Capuano, G P; Capuano, C

    2012-03-01

    The objective of this work is to evaluate the usefulness of a standardized clinical classification of hydroceles in lymphatic filariasis endemic countries to guide their surgical management. 64 patients with hydroceles were operated in 2009-2010, in Level II hospitals (WHO classification), during two visits to Fiji, by the same mobile surgical team. The number of hydroceles treated was 83. We developed and evaluated a much needed clinical classification of hydroceles based on four criteria: Type (uni/bilateral); Side (left/right); Stage of enlargement of the scrotum rated from I to VI; Grade of burial of the penis rated from 0 to 4. It lead to the conclusion that 1) A Stage I or II hydrocele, associated with Grade 0 or 1 penis burial could be considered a "Simple Hydrocele". The surgical treatment is simple with no anticipated early complication. WHO Level II of health care structure seems adapted. 2) A Stage III or IV hydrocele associated with Grade 2, 3 or 4 penis burial could be considered a "Complicated Hydrocele". The operation is longer, more complicated and the possibility of occurrence of complications seems greater. A level III health care facility would be more adapted under the normal functioning of the health system. We conclude that a standardized clinical classification of hydroceles based on the Stage of enlargement of the scrotum and the Grade of burial of the penis appears to be a useful tool to guide the decision about the level of care and the surgical technique required. We use the same classification for penoscrotal lymphoedema. A decision tree is presented for the management of hydroceles in lymphatic filariasis endemic countries which could usefully complement the "Algorithm for management of scrotal swelling" proposed by WHO in 2002. An international classification system of hydroceles would also allow standardization and facilitate study design and comparisons of their results.

  1. A multi-temporal analysis approach for land cover mapping in support of nuclear incident response

    NASA Astrophysics Data System (ADS)

    Sah, Shagan; van Aardt, Jan A. N.; McKeown, Donald M.; Messinger, David W.

    2012-06-01

    Remote sensing can be used to rapidly generate land use maps for assisting emergency response personnel with resource deployment decisions and impact assessments. In this study we focus on constructing accurate land cover maps to map the impacted area in the case of a nuclear material release. The proposed methodology involves integration of results from two different approaches to increase classification accuracy. The data used included RapidEye scenes over Nine Mile Point Nuclear Power Station (Oswego, NY). The first step was building a coarse-scale land cover map from freely available, high temporal resolution, MODIS data using a time-series approach. In the case of a nuclear accident, high spatial resolution commercial satellites such as RapidEye or IKONOS can acquire images of the affected area. Land use maps from the two image sources were integrated using a probability-based approach. Classification results were obtained for four land classes - forest, urban, water and vegetation - using Euclidean and Mahalanobis distances as metrics. Despite the coarse resolution of MODIS pixels, acceptable accuracies were obtained using time series features. The overall accuracies using the fusion based approach were in the neighborhood of 80%, when compared with GIS data sets from New York State. The classifications were augmented using this fused approach, with few supplementary advantages such as correction for cloud cover and independence from time of year. We concluded that this method would generate highly accurate land maps, using coarse spatial resolution time series satellite imagery and a single date, high spatial resolution, multi-spectral image.

  2. Nuclear Reactor Physics

    NASA Astrophysics Data System (ADS)

    Stacey, Weston M.

    2001-02-01

    An authoritative textbook and up-to-date professional's guide to basic and advanced principles and practices Nuclear reactors now account for a significant portion of the electrical power generated worldwide. At the same time, the past few decades have seen an ever-increasing number of industrial, medical, military, and research applications for nuclear reactors. Nuclear reactor physics is the core discipline of nuclear engineering, and as the first comprehensive textbook and reference on basic and advanced nuclear reactor physics to appear in a quarter century, this book fills a large gap in the professional literature. Nuclear Reactor Physics is a textbook for students new to the subject, for others who need a basic understanding of how nuclear reactors work, as well as for those who are, or wish to become, specialists in nuclear reactor physics and reactor physics computations. It is also a valuable resource for engineers responsible for the operation of nuclear reactors. Dr. Weston Stacey begins with clear presentations of the basic physical principles, nuclear data, and computational methodology needed to understand both the static and dynamic behaviors of nuclear reactors. This is followed by in-depth discussions of advanced concepts, including extensive treatment of neutron transport computational methods. As an aid to comprehension and quick mastery of computational skills, he provides numerous examples illustrating step-by-step procedures for performing the calculations described and chapter-end problems. Nuclear Reactor Physics is a useful textbook and working reference. It is an excellent self-teaching guide for research scientists, engineers, and technicians involved in industrial, research, and military applications of nuclear reactors, as well as government regulators who wish to increase their understanding of nuclear reactors.

  3. [The electronic use of the NANDA-, NOC- and NIC- classifications and implications for nursing practice].

    PubMed

    Bernhart-Just, Alexandra; Hillewerth, Kathrin; Holzer-Pruss, Christina; Paprotny, Monika; Zimmermann Heinrich, Heidi

    2009-12-01

    The data model developed on behalf of the Nursing Service Commission of the Canton of Zurich (Pflegedienstkommission des Kantons Zürich) is based on the NANDA nursing diagnoses, the Nursing Outcome Classification, and the Nursing Intervention Classification (NNN Classifications). It also includes integrated functions for cost-centered accounting, service recording, and the Swiss Nursing Minimum Data Set. The data model uses the NNN classifications to map a possible form of the nursing process in the electronic patient health record, where the nurse can choose nursing diagnoses, outcomes, and interventions relevant to the patient situation. The nurses' choice is guided both by the different classifications and their linkages, and the use of specific text components pre-defined for each classification and accessible through the respective linkages. This article describes the developed data model and illustrates its clinical application in a specific patient's situation. Preparatory work required for the implementation of NNN classifications in practical nursing such as content filtering and the creation of linkages between the NNN classifications are described. Against the background of documentation of the nursing process based on the DAPEP(1) data model, possible changes and requirements are deduced. The article provides a contribution to the discussion of a change in documentation of the nursing process by implementing nursing classifications in electronic patient records.

  4. Solid-State Nuclear Power

    NASA Technical Reports Server (NTRS)

    George, Jeffrey A.

    2012-01-01

    A strategy for "Solid-State" Nuclear Power is proposed to guide development of technologies and systems into the second 50 years of nuclear spaceflight. The strategy emphasizes a simple and highly integrated system architecture with few moving parts or fluid loops; the leverage of modern advances in materials, manufacturing, semiconductors, microelectromechanical and nanotechnology devices; and the targeted advancement of high temperature nuclear fuels, materials and static power conversion to enable high performance from simple system topologies.

  5. 78 FR 663 - Decommissioning Planning During Operations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-04

    ...] Decommissioning Planning During Operations AGENCY: Nuclear Regulatory Commission. ACTION: Regulatory guide..., ``Decommissioning Planning During Operations.'' The guide describes a method that the NRC staff considers acceptable for use by holders of licenses in complying with the NRC's Decommissioning Planning Rule (DPR) (76 FR...

  6. 75 FR 35508 - Draft Regulatory Guide: Issuance, Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-22

    ... Systems and Networks,'' requires licensees to develop cyber-security plans and programs to protect critical digital assets, including digital safety systems, from malicious cyber attacks. Regulatory Guide 5.71, ``Cyber Security Programs for Nuclear Facilities,'' provides guidance to meet the requirements of...

  7. 78 FR 37850 - Quality Assurance Program Requirements (Operations)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-24

    ... NUCLEAR REGULATORY COMMISSION [NRC-2013-0021] Quality Assurance Program Requirements (Operations... Regulatory Commission (NRC) is issuing a revision to Regulatory Guide (RG) 1.33, ``Quality Assurance Program... managerial and administrative Quality Assurance (QA) controls for nuclear power plants during operations...

  8. Long-term proliferation and safeguards issues in future technologies

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Keisch, B.; Auerbach, C.; Fainberg, A.

    1986-02-01

    The purpose of the task was to assess the effect of potential new technologies, nuclear and non-nuclear, on safeguards needs and non-proliferation policies, and to explore possible solutions to some of the problems envisaged. Eight subdivisions were considered: New Enrichment Technologies; Non-Aqueous Reprocessing Technologies; Fusion; Accelerator-Driven Reactor Systems; New Reactor Types; Heavy Water and Deuterium; Long-Term Storage of Spent Fuel; and Other Future Technologies (Non-Nuclear). For each of these subdivisions, a careful review of the current world-wide effort in the field provided a means of subjectively estimating the viability and qualitative probability of fruition of promising technologies. Technologies for whichmore » safeguards and non-proliferation requirements have been thoroughly considered by others were not restudied here (e.g., the Fast Breeder Reactor). The time scale considered was 5 to 40 years for possible initial demonstration although, in some cases, a somewhat optimistic viewpoint was embraced. Conventional nuclear-material safeguards are only part of the overall non-proliferation regime. Other aspects are international agreements, export controls on sensitive technologies, classification of information, intelligence gathering, and diplomatic initiatives. The focus here is on safeguards, export controls, and classification.« less

  9. Development of the Updated Environmental Protection Agency Manual of Protective Action Guides (PAGS) and Protective Actions for Nuclear Incidents

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Carter, L.M.

    2008-07-01

    As a student intern with the United States Environmental Protection Agency (EPA) Headquarters, the author was trained in the National Response Plan (NRP) and assisted in the editing of the new (unpublished) EPA Protective Action Guides (PAGs) [1] which has been revised in light of the perceived post 9/11 potential for 'Dirty Bomb' and 'Improvised Nuclear Device' attacks on civilian areas. Technical aspects and the public policy aspects of developing the new guides are discussed. Early Phase initial responses discussed include: Notification of state and/or local authorities, immediate evacuation/sheltering prior to release information or measurements, monitoring of releases and exposuremore » rate measurements, estimation of dose consequences, implementation of protective actions in other areas. The new PAG clarifies the use of 1992 PAGs [2] for incidents other than nuclear power plant accidents, lowers projected thyroid dose for potassium iodine (KI), provides drinking water guidance, includes guidance for long-term site restoration, and updates dosimetry from ICRP 26 to ICRP 60. (authors)« less

  10. Your Career and Nuclear Weapons: A Guide for Young Scientists and Engineers.

    ERIC Educational Resources Information Center

    Albrecht, Andreas; And Others

    This four-part booklet examines various issues related to nuclear weapons and how they will affect an individual working as a scientist or engineer. It provides information about the history of nuclear weapons, about the weapons industry which produces them, and about new weapons programs. Issues are raised so that new or future graduates may make…

  11. 10 CFR Appendix I to Part 50 - Numerical Guides for Design Objectives and Limiting Conditions for Operation To Meet the...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... in Light-Water-Cooled Nuclear Power Reactor Effluents I Appendix I to Part 50 Energy NUCLEAR... Criterion “As Low as is Reasonably Achievable” for Radioactive Material in Light-Water-Cooled Nuclear Power Reactor Effluents SECTION I. Introduction. Section 50.34a provides that an application for a construction...

  12. 10 CFR Appendix I to Part 50 - Numerical Guides for Design Objectives and Limiting Conditions for Operation To Meet the...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... in Light-Water-Cooled Nuclear Power Reactor Effluents I Appendix I to Part 50 Energy NUCLEAR... Criterion “As Low as is Reasonably Achievable” for Radioactive Material in Light-Water-Cooled Nuclear Power Reactor Effluents SECTION I. Introduction. Section 50.34a provides that an application for a construction...

  13. Automated Feature Identification and Classification Using Automated Feature Weighted Self Organizing Map (FWSOM)

    NASA Astrophysics Data System (ADS)

    Starkey, Andrew; Usman Ahmad, Aliyu; Hamdoun, Hassan

    2017-10-01

    This paper investigates the application of a novel method for classification called Feature Weighted Self Organizing Map (FWSOM) that analyses the topology information of a converged standard Self Organizing Map (SOM) to automatically guide the selection of important inputs during training for improved classification of data with redundant inputs, examined against two traditional approaches namely neural networks and Support Vector Machines (SVM) for the classification of EEG data as presented in previous work. In particular, the novel method looks to identify the features that are important for classification automatically, and in this way the important features can be used to improve the diagnostic ability of any of the above methods. The paper presents the results and shows how the automated identification of the important features successfully identified the important features in the dataset and how this results in an improvement of the classification results for all methods apart from linear discriminatory methods which cannot separate the underlying nonlinear relationship in the data. The FWSOM in addition to achieving higher classification accuracy has given insights into what features are important in the classification of each class (left and right-hand movements), and these are corroborated by already published work in this area.

  14. Effects of a didactic and guided-imagery intervention regarding horrendous death by nuclear war upon fear of death, health locus of control, and social responsibility in health education college students

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Campanelli, L.C.

    1987-01-01

    This investigation studied the effects of a videotaped lecture explaining horrendous death theory, with a guided imagery component describing horrendous death of a beloved other, upon action toward anti-nuclearism and three individual difference variables. The primary purpose of this study was to determine the effects of a videotaped lecture on college students' fear of death, health locus of control, and social responsibility. A second purpose was to determine whether participants who viewed the videotape were likely to sign a petition against nuclear war, in support of the Physicians for Social Responsibility's position against nuclearism. One hundred fifty-two (152) college studentsmore » participated in this study; approximately 55% were female and 50% were seniors. No significant differences were found regarding individual difference variables, except concerning fear of death of self between death education and non-death education experimental groups. Although an interaction effect was found, the hypothesis that experimental groups would be more likely to sign the petition against nuclear was not confirmed.« less

  15. 75 FR 79049 - Final Regulatory Guide: Issuance, Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-17

    ... (RG) 5.80, ``Pressure-Sensitive and Tamper-Indicating Device Seals for Material Control and Accounting... and licenses. Regulatory Guide 5.80, ``Pressure-Sensitive and Tamper-Indicating Device Seals for... and Use of Pressure-Sensitive Seals on Containers for Onsite Storage of Special Nuclear Material...

  16. 77 FR 18871 - Administrative Guide for Verifying Compliance With Packaging Requirements for Shipment and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-28

    ... Packaging Requirements for Shipment and Receipt of Radioactive Material AGENCY: Nuclear Regulatory... with Packaging Requirements for Shipment and Receipt of Radioactive Material.'' This regulatory guide... for transporting licensed material under 10 CFR part 71, ``Packaging and Transportation of Radioactive...

  17. Criticality Safety Basics for INL FMHs and CSOs

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    V. L. Putman

    2012-04-01

    Nuclear power is a valuable and efficient energy alternative in our energy-intensive society. However, material that can generate nuclear power has properties that require this material be handled with caution. If improperly handled, a criticality accident could result, which could severely harm workers. This document is a modular self-study guide about Criticality Safety Principles. This guide's purpose it to help you work safely in areas where fissionable nuclear materials may be present, avoiding the severe radiological and programmatic impacts of a criticality accident. It is designed to stress the fundamental physical concepts behind criticality controls and the importance of criticalitymore » safety when handling fissionable materials outside nuclear reactors. This study guide was developed for fissionable-material-handler and criticality-safety-officer candidates to use with related web-based course 00INL189, BEA Criticality Safety Principles, and to help prepare for the course exams. These individuals must understand basic information presented here. This guide may also be useful to other Idaho National Laboratory personnel who must know criticality safety basics to perform their assignments safely or to design critically safe equipment or operations. This guide also includes additional information that will not be included in 00INL189 tests. The additional information is in appendices and paragraphs with headings that begin with 'Did you know,' or with, 'Been there Done that'. Fissionable-material-handler and criticality-safety-officer candidates may review additional information at their own discretion. This guide is revised as needed to reflect program changes, user requests, and better information. Issued in 2006, Revision 0 established the basic text and integrated various programs from former contractors. Revision 1 incorporates operation and program changes implemented since 2006. It also incorporates suggestions, clarifications, and additional information from readers and from personnel who took course 00INL189. Revision 1 also completely reorganized the training to better emphasize physical concepts behind the criticality controls that fissionable material handlers and criticality safety officers must understand. The reorganization is based on and consistent with changes made to course 00INL189 due to a review of course exam results and to discussions with personnel who conduct area-specific training.« less

  18. Automated Classification of Phonological Errors in Aphasic Language

    PubMed Central

    Ahuja, Sanjeev B.; Reggia, James A.; Berndt, Rita S.

    1984-01-01

    Using heuristically-guided state space search, a prototype program has been developed to simulate and classify phonemic errors occurring in the speech of neurologically-impaired patients. Simulations are based on an interchangeable rule/operator set of elementary errors which represent a theory of phonemic processing faults. This work introduces and evaluates a novel approach to error simulation and classification, it provides a prototype simulation tool for neurolinguistic research, and it forms the initial phase of a larger research effort involving computer modelling of neurolinguistic processes.

  19. Electrocardiography: A Technologist's Guide to Interpretation.

    PubMed

    Tso, Colin; Currie, Geoffrey M; Gilmore, David; Kiat, Hosen

    2015-12-01

    The nuclear medicine technologist works with electrocardiography when performing cardiac stress testing and gated cardiac imaging and when monitoring critical patients. To enhance patient care, basic electrocardiogram interpretation skills and recognition of key arrhythmias are essential for the nuclear medicine technologist. This article provides insight into the anatomy of an electrocardiogram trace, covers basic electrocardiogram interpretation methods, and describes an example case typical in the nuclear medicine environment. © 2015 by the Society of Nuclear Medicine and Molecular Imaging, Inc.

  20. Bats in the Classroom: A Conceptual Guide for Biology Teachers.

    ERIC Educational Resources Information Center

    Rankin, W. T.; Lewis, Norma G.

    2002-01-01

    Explains how to use bats to introduce different biological concepts such as classification and phylogeny, altruistic behavior, flight, coevolution, or physiological adaptations. Discusses common myths regarding bats and provides information on additional classroom materials. (YDS)

  1. 7 CFR 658.5 - Criteria.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... information from several sources including national cooperative soil surveys or other acceptable soil surveys, NRCS field office technical guides, soil potential ratings or soil productivity ratings, land capability classifications, and important farmland determinations. Based on this information, groups of soils...

  2. 7 CFR 658.5 - Criteria.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... information from several sources including national cooperative soil surveys or other acceptable soil surveys, NRCS field office technical guides, soil potential ratings or soil productivity ratings, land capability classifications, and important farmland determinations. Based on this information, groups of soils...

  3. Inherited Congenital Cataract: A Guide to Suspect the Genetic Etiology in the Cataract Genesis

    PubMed Central

    Messina-Baas, Olga; Cuevas-Covarrubias, Sergio A.

    2017-01-01

    Cataracts are the principal cause of treatable blindness worldwide. Inherited congenital cataract (CC) shows all types of inheritance patterns in a syndromic and nonsyndromic form. There are more than 100 genes associated with cataract with a predominance of autosomal dominant inheritance. A cataract is defined as an opacity of the lens producing a variation of the refractive index of the lens. This variation derives from modifications in the lens structure resulting in light scattering, frequently a consequence of a significant concentration of high-molecular-weight protein aggregates. The aim of this review is to introduce a guide to identify the gene involved in inherited CC. Due to the manifold clinical and genetic heterogeneity, we discarded the cataract phenotype as a cardinal sign; a 4-group classification with the genes implicated in inherited CC is proposed. We consider that this classification will assist in identifying the probable gene involved in inherited CC. PMID:28611546

  4. Application of NEPA to nuclear weapons production, storage, and testing Weinberger v. Catholic Action of Hawaii/Peace Education Project

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sauber, A.J.

    The National Environmental Policy Act (NEPA) requirement of environmental impact statements for the testing of military equipment, specifically nuclear weapons, conflicts with national security objectives. The author examines NEPA and the Freedom of Information Act (FOIA) in terms of the environmental effects of weapons testing and the relevant case law. The Supreme Court's decision in Catholic Action of Hawaii/Peace Education Project sought to resolve the conflict by distinguishing between a project which is contemplated and one which is proposed. The classification scheme embodied in the FOIA exemption for national security may cause unwarranted frustration of NEPA's goals. The author outlinesmore » a new classification system and review mechanism that could curb military abuse in this area.« less

  5. 75 FR 9626 - Notice of Issuance of Regulatory Guide

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-03

    ... maintain variables and systems that can affect the fission process, the integrity of the reactor core, the... on some other defined basis. GDC 24 requires that interconnection of the protection and control..., Regulatory Guide Development Branch, Division of Engineering, Office of Nuclear Regulatory Research. [FR Doc...

  6. 78 FR 64030 - Monitoring Criteria and Methods To Calculate Occupational Radiation Doses

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-25

    ... NUCLEAR REGULATORY COMMISSION [NRC-2013-0234] Monitoring Criteria and Methods To Calculate... regulatory guide (DG), DG-8031, ``Monitoring Criteria and Methods to Calculate Occupational Radiation Doses.'' This guide describes methods that the NRC staff considers acceptable for licensees to use to determine...

  7. Industrial Radiography Instructor's Guide.

    ERIC Educational Resources Information Center

    Richardson, Harry D.

    The curriculum guide was developed for teacher use in an 80-hour course for industrial radiographers. The units include: (1) The Structure of Matter and Radiation, (2) Nuclear Reactions and Radioisotopes, (3) The Nature and Consequences of Radiation Exposure, (4) Radiation Attenuation, (5) Absorption of Radiation, (6) Radiation Detection and…

  8. Perspectives on Next Steps in Classification of Orofacial Pain – Part 2: Role of psychosocial factors

    PubMed Central

    Durham, Justin; Raphael, Karen G.; Benoliel, Rafael; Ceusters, Werner; Michelotti, Ambra; Ohrbach, Richard

    2015-01-01

    This paper was initiated by a symposium, in which the present authors contributed, organised by the International RDC/TMD Consortium Network in March 2013. The purpose of the paper is to review the status of biobehavioural research – both quantitative and qualitative – related to orofacial pain with respect to the etiology, pathophysiology, diagnosis and management of orofacial pain conditions, and how this information can optimally be used for developing a structured orofacial pain classification system for research. In particular, we address: representation of psychosocial entities in classification systems, use of qualitative research to identify and understand the full scope of psychosocial entities and their interaction, and the usage of classification system for guiding treatment. We then provide recommendations for addressing these problems, including how ontological principles can inform this process. PMID:26257252

  9. Classification of full-thickness rotator cuff lesions: a review

    PubMed Central

    Lädermann, Alexandre; Burkhart, Stephen S.; Hoffmeyer, Pierre; Neyton, Lionel; Collin, Philippe; Yates, Evan; Denard, Patrick J.

    2016-01-01

    Rotator cuff lesions (RCL) have considerable variability in location, tear pattern, functional impairment, and repairability. Historical classifications for differentiating these lesions have been based upon factors such as the size and shape of the tear, and the degree of atrophy and fatty infiltration. Additional recent descriptions include bipolar rotator cuff insufficiency, ‘Fosbury flop tears’, and musculotendinous lesions. Recommended treatment is based on the location of the lesion, patient factors and associated pathology, and often includes personal experience and data from case series. Development of a more comprehensive classification which integrates historical and newer descriptions of RCLs may help to guide treatment further. Cite this article: Lädermann A, Burkhart SS, Hoffmeyer P, et al. Classification of full thickness rotator cuff lesions: a review. EFORT Open Rev 2016;1:420-430. DOI: 10.1302/2058-5241.1.160005. PMID:28461921

  10. Nuclear fuel element nut retainer cup. [PWR

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Walton, L.A.

    1977-07-19

    A typical embodiment has an end fitting for a nuclear reactor fuel element that is joined to the control rod guide tubes by means of a nut plate assembly. The nut plate assembly has an array of nuts, each engaging the respective threaded end of the control rod guide tubes. The nuts, moreover, are retained on the plate during handling and before fuel element assembly by means of hollow cylindrical locking cups that are brazed to the plate and loosely circumscribe the individual enclosed nuts. After the nuts are threaded onto the respective guide tube ends, the locking cups aremore » partially deformed to prevent one or more of the nuts from working loose during reactor operation. The locking cups also prevent loose or broken end fitting parts from becoming entrained in the reactor coolant.« less

  11. Accurate diagnosis of thyroid follicular lesions from nuclear morphology using supervised learning.

    PubMed

    Ozolek, John A; Tosun, Akif Burak; Wang, Wei; Chen, Cheng; Kolouri, Soheil; Basu, Saurav; Huang, Hu; Rohde, Gustavo K

    2014-07-01

    Follicular lesions of the thyroid remain significant diagnostic challenges in surgical pathology and cytology. The diagnosis often requires considerable resources and ancillary tests including immunohistochemistry, molecular studies, and expert consultation. Visual analyses of nuclear morphological features, generally speaking, have not been helpful in distinguishing this group of lesions. Here we describe a method for distinguishing between follicular lesions of the thyroid based on nuclear morphology. The method utilizes an optimal transport-based linear embedding for segmented nuclei, together with an adaptation of existing classification methods. We show the method outputs assignments (classification results) which are near perfectly correlated with the clinical diagnosis of several lesion types' lesions utilizing a database of 94 patients in total. Experimental comparisons also show the new method can significantly outperform standard numerical feature-type methods in terms of agreement with the clinical diagnosis gold standard. In addition, the new method could potentially be used to derive insights into biologically meaningful nuclear morphology differences in these lesions. Our methods could be incorporated into a tool for pathologists to aid in distinguishing between follicular lesions of the thyroid. In addition, these results could potentially provide nuclear morphological correlates of biological behavior and reduce health care costs by decreasing histotechnician and pathologist time and obviating the need for ancillary testing. Copyright © 2014 Elsevier B.V. All rights reserved.

  12. Monitoring and Morphologic Classification of Pediatric Cataract Using Slit-Lamp-Adapted Photography.

    PubMed

    Long, Erping; Lin, Zhuoling; Chen, Jingjing; Liu, Zhenzhen; Cao, Qianzhong; Lin, Haotian; Chen, Weirong; Liu, Yizhi

    2017-11-01

    To investigate the feasibility of pediatric cataract monitoring and morphologic classification using slit lamp-adapted anterior segmental photography in a large cohort that included uncooperative children. Patients registered in the Childhood Cataract Program of the Chinese Ministry of Health were prospectively selected. Eligible patients underwent slit-lamp adapted anterior segmental photography to record and monitor the morphology of their cataractous lenses. A set of assistance techniques for slit lamp-adapted photography was developed to instruct the parents of uncooperative children how to help maintain the child's head position and keep the eyes open after sleep aid administration. Briefly, slit lamp-adapted photography was completed for all 438 children, including 260 (59.4%) uncooperative children with our assistance techniques. All 746 images of 438 patients successfully confirmed the diagnoses and classifications. Considering the lesion location, pediatric cataract morphologies could be objectively classified into the seven following types: total; nuclear; polar, including two subtypes (anterior and posterior); lamellar; nuclear combined with cortical, including three subtypes (coral-like, dust-like, and blue-dot); cortical; and Y suture. The top three types of unilateral cataracts were polar (55, 42.3%), total (42, 32.3%), and nuclear (23, 17.7%); and the top three types of bilateral cataracts were nuclear (110, 35.8%), total (102, 33.2%), and lamellar (34, 11.1%). Slit lamp-adapted anterior segmental photography is applicable for monitoring and classifying the morphologies of pediatric cataracts and is even safe and feasible for uncooperative children with assistance techniques and sleep aid administration. This study proposes a novel strategy for the preoperative evaluation and evidence-based management of pediatric ophthalmology (Clinical Trials.gov, NCT02748031).

  13. Academic Radiologist Subspecialty Identification Using a Novel Claims-Based Classification System.

    PubMed

    Rosenkrantz, Andrew B; Wang, Wenyi; Hughes, Danny R; Ginocchio, Luke A; Rosman, David A; Duszak, Richard

    2017-06-01

    The objective of the present study is to assess the feasibility of a novel claims-based classification system for payer identification of academic radiologist subspecialties. Using a categorization scheme based on the Neiman Imaging Types of Service (NITOS) system, we mapped the Medicare Part B services billed by all radiologists from 2012 to 2014, assigning them to the following subspecialty categories: abdominal imaging, breast imaging, cardiothoracic imaging, musculoskeletal imaging, nuclear medicine, interventional radiology, and neuroradiology. The percentage of subspecialty work relative value units (RVUs) to total billed work RVUs was calculated for each radiologist nationwide. For radiologists at the top 20 academic departments funded by the National Institutes of Health, those percentages were compared with subspecialties designated on faculty websites. NITOS-based subspecialty assignments were also compared with the only radiologist subspecialty classifications currently recognized by Medicare (i.e., nuclear medicine and interventional radiology). Of 1012 academic radiologists studied, the median percentage of Medicare-billed NITOS-based subspecialty work RVUs matching the subspecialty designated on radiologists' own websites ranged from 71.3% (for nuclear medicine) to 98.9% (for neuroradiology). A NITOS-based work RVU threshold of 50% correctly classified 89.8% of radiologists (5.9% were not mapped to any subspecialty; subspecialty error rate, 4.2%). In contrast, existing Medicare provider codes identified only 46.7% of nuclear medicine physicians and 39.4% of interventional radiologists. Using a framework based on a recently established imaging health services research tool that maps service codes based on imaging modality and body region, Medicare claims data can be used to consistently identify academic radiologists by subspecialty in a manner not possible with the use of existing Medicare physician specialty identifiers. This method may facilitate more appropriate performance metrics for subspecialty academic physicians under emerging value-based payment models.

  14. Implementation of a documentation model comprising nursing terminologies--theoretical and methodological issues.

    PubMed

    von Krogh, Gunn; Nåden, Dagfinn

    2008-04-01

    To describe and discuss theoretical and methodological issues of implementation of a nursing services documentation model comprising NANDA nursing diagnoses, Nursing Intervention Classification and Nursing Outcome Classification terminologies. The model is developed for electronic patient record and was implemented in a psychiatric hospital on an organizational level and on five test wards in 2001-2005. The theory of Rogers guided the process of innovation, whereas the implementation procedure of McCloskey and Bulecheck combined with adult learning principals guided the test site implementation. The test wards managed in different degrees to adopt the model. Two wards succeeded fully, including a ward with high percentage of staff with interdisciplinary background. Better planning regarding the impact of the organization's innovative aptitude, the innovation strategies and the use of differentiated methods regarding the clinician's individual premises for learning nursing terminologies might have enhanced the adoption to the model. To better understand the nature of barriers and the importance of careful planning regarding the implementation of electronic patient record elements in nursing care services, focusing on nursing terminologies. Further to indicate how a theory and specific procedure can be used to guide the process of implementation throughout the different levels of management.

  15. Report: EPA Improved Its National Security Information Program, but Some Improvements Still Needed

    EPA Pesticide Factsheets

    Report #16-P-0196, June 2, 2016. The EPA will continue to improve its national security information program by completing information classification guides that can be used uniformly and consistently throughout the agency.

  16. Provisional in-silico biopharmaceutics classification (BCS) to guide oral drug product development

    PubMed Central

    Wolk, Omri; Agbaria, Riad; Dahan, Arik

    2014-01-01

    The main objective of this work was to investigate in-silico predictions of physicochemical properties, in order to guide oral drug development by provisional biopharmaceutics classification system (BCS). Four in-silico methods were used to estimate LogP: group contribution (CLogP) using two different software programs, atom contribution (ALogP), and element contribution (KLogP). The correlations (r2) of CLogP, ALogP and KLogP versus measured LogP data were 0.97, 0.82, and 0.71, respectively. The classification of drugs with reported intestinal permeability in humans was correct for 64.3%–72.4% of the 29 drugs on the dataset, and for 81.82%–90.91% of the 22 drugs that are passively absorbed using the different in-silico algorithms. Similar permeability classification was obtained with the various in-silico methods. The in-silico calculations, along with experimental melting points, were then incorporated into a thermodynamic equation for solubility estimations that largely matched the reference solubility values. It was revealed that the effect of melting point on the solubility is minor compared to the partition coefficient, and an average melting point (162.7°C) could replace the experimental values, with similar results. The in-silico methods classified 20.76% (±3.07%) as Class 1, 41.51% (±3.32%) as Class 2, 30.49% (±4.47%) as Class 3, and 6.27% (±4.39%) as Class 4. In conclusion, in-silico methods can be used for BCS classification of drugs in early development, from merely their molecular formula and without foreknowledge of their chemical structure, which will allow for the improved selection, engineering, and developability of candidates. These in-silico methods could enhance success rates, reduce costs, and accelerate oral drug products development. PMID:25284986

  17. Gynecomastia Classification for Surgical Management: A Systematic Review and Novel Classification System.

    PubMed

    Waltho, Daniel; Hatchell, Alexandra; Thoma, Achilleas

    2017-03-01

    Gynecomastia is a common deformity of the male breast, where certain cases warrant surgical management. There are several surgical options, which vary depending on the breast characteristics. To guide surgical management, several classification systems for gynecomastia have been proposed. A systematic review was performed to (1) identify all classification systems for the surgical management of gynecomastia, and (2) determine the adequacy of these classification systems to appropriately categorize the condition for surgical decision-making. The search yielded 1012 articles, and 11 articles were included in the review. Eleven classification systems in total were ascertained, and a total of 10 unique features were identified: (1) breast size, (2) skin redundancy, (3) breast ptosis, (4) tissue predominance, (5) upper abdominal laxity, (6) breast tuberosity, (7) nipple malposition, (8) chest shape, (9) absence of sternal notch, and (10) breast skin elasticity. On average, classification systems included two or three of these features. Breast size and ptosis were the most commonly included features. Based on their review of the current classification systems, the authors believe the ideal classification system should be universal and cater to all causes of gynecomastia; be surgically useful and easy to use; and should include a comprehensive set of clinically appropriate patient-related features, such as breast size, breast ptosis, tissue predominance, and skin redundancy. None of the current classification systems appears to fulfill these criteria.

  18. 77 FR 55877 - Initial Test Program of Condensate and Feedwater Systems for Light-Water Reactors

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-11

    ...-492- 3668; email: [email protected] . NRC's Agencywide Documents Access and Management System... Systems for Light-Water Reactors AGENCY: Nuclear Regulatory Commission. ACTION: Regulatory guide; issuance... Systems for Boiling Water Reactor Power Plants.'' This regulatory guide is being revised to: (1) Expand...

  19. Energy from the Atom.

    ERIC Educational Resources Information Center

    Smith, Patricia L.

    This curriculum guide was written to supplement fifth and sixth grade science units on matter and energy. It was designed to provide more in-depth material on the atom. The first part, "Teacher Guide," contains background information, biographical sketches of persons in the history of nuclear energy, vocabulary, answer sheets, management sheets…

  20. 75 FR 16516 - Draft Regulatory Guide: Issuance, Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-01

    ...: R.A. Jervey, U.S. Nuclear Regulatory Commission, Washington, DC 20555-0001, telephone: (301) 251...'' series. This series was developed to describe and make available to the public such information as.... Although a time limit is given, comments and suggestions in connection with items for inclusion in guides...

  1. 75 FR 16525 - Notice of Issuance of Regulatory Guide

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-01

    ... CONTACT: Mekonen M. Bayssie, Regulatory Guide Development Branch, Division of Engineering, Office of...) 251-7489 or e-mail [email protected] . SUPPLEMENTARY INFORMATION: I. Introduction The U.S..., Division of Engineering, Office of Nuclear Regulatory Research. [FR Doc. 2010-7391 Filed 3-31-10; 8:45 am...

  2. NUCLEAR SCIENCE, AN INTRODUCTORY COURSE.

    ERIC Educational Resources Information Center

    SULCOSKI, JOHN W.

    THIS CURRICULUM GUIDE DESCRIBES A TWELFTH-GRADE INTERDISCIPLINARY, INTRODUCTORY NUCLEAR SCIENCE COURSE. IT IS BELIEVED TO FILL THE NEED FOR AN ADVANCED COURSE THAT IS TIMELY, CHALLENGING, AND APPROPRIATE AS A SEQUENTIAL ADDITION TO THE BIOLOGY-CHEMISTRY-PHYSICS SEQUENCE. PRELIMINARY INFORMATION COVERS SUCH MATTERS AS (1) RADIOISOTOPE WORK AREAS,…

  3. Nuclear Science Teaching Aids and Activities.

    ERIC Educational Resources Information Center

    Woodburn, John H.

    This publication is a sourcebook for science teachers. It provides guides for basic laboratory work in nuclear energy, suggesting various teacher and student demonstrations. Ideas for science clubs, science fairs, and project research seminars are presented. Problem-solving activities for both science and mathematics classes are included, as well…

  4. Despair and Personal Power in the Nuclear Age.

    ERIC Educational Resources Information Center

    Macy, Joanna Rogers

    This guide to personal empowerment provides 47 exercises for dealing with feelings of despair, isolation, and powerlessness associated with the growing threat of nuclear war, progressive destruction of the environment, and unprecedented human misery. The first of eight chapters describes psychological responses. to planetary perils and discusses…

  5. Gender classification system in uncontrolled environments

    NASA Astrophysics Data System (ADS)

    Zeng, Pingping; Zhang, Yu-Jin; Duan, Fei

    2011-01-01

    Most face analysis systems available today perform mainly on restricted databases of images in terms of size, age, illumination. In addition, it is frequently assumed that all images are frontal and unconcealed. Actually, in a non-guided real-time supervision, the face pictures taken may often be partially covered and with head rotation less or more. In this paper, a special system supposed to be used in real-time surveillance with un-calibrated camera and non-guided photography is described. It mainly consists of five parts: face detection, non-face filtering, best-angle face selection, texture normalization, and gender classification. Emphases are focused on non-face filtering and best-angle face selection parts as well as texture normalization. Best-angle faces are figured out by PCA reconstruction, which equals to an implicit face alignment and results in a huge increase of the accuracy for gender classification. Dynamic skin model and a masked PCA reconstruction algorithm are applied to filter out faces detected in error. In order to fully include facial-texture and shape-outline features, a hybrid feature that is a combination of Gabor wavelet and PHoG (pyramid histogram of gradients) was proposed to equitable inner texture and outer contour. Comparative study on the effects of different non-face filtering and texture masking methods in the context of gender classification by SVM is reported through experiments on a set of UT (a company name) face images, a large number of internet images and CAS (Chinese Academy of Sciences) face database. Some encouraging results are obtained.

  6. Statewide land cover derived from multiseasonal Landsat TM data: A retrospective of the WISCLAND project

    USGS Publications Warehouse

    Reese, H.M.; Lillesand, T.M.; Nagel, D.E.; Stewart, J.S.; Goldmann, R.A.; Simmons, T.E.; Chipman, J.W.; Tessar, P.A.

    2002-01-01

    Landsat Thematic Mapper (TM) data were the basis in production of a statewide land cover data set for Wisconsin, undertaken in partnership with U.S. Geological Survey's (USGS) Gap Analysis Program (GAP). The data set contained seven classes comparable to Anderson Level I and 24 classes comparable to Anderson Level II/III. Twelve scenes of dual-date TM data were processed with methods that included principal components analysis, stratification into spectrally consistent units, separate classification of upland, wetland, and urban areas, and a hybrid supervised/unsupervised classification called "guided clustering." The final data had overall accuracies of 94% for Anderson Level I upland classes, 77% for Level II/III upland classes, and 84% for Level II/III wetland classes. Classification accuracies for deciduous and coniferous forest were 95% and 93%, respectively, and forest species' overall accuracies ranged from 70% to 84%. Limited availability of acceptable imagery necessitated use of an early May date in a majority of scene pairs, perhaps contributing to lower accuracy for upland deciduous forest species. The mixed deciduous/coniferous forest class had the lowest accuracy, most likely due to distinctly classifying a purely mixed class. Mixed forest signatures containing oak were often confused with pure oak. Guided clustering was seen as an efficient classification method, especially at the tree species level, although its success relied in part on image dates, accurate ground troth, and some analyst intervention. ?? 2002 Elsevier Science Inc. All rights reserved.

  7. Proposal of a new radiological classification system for spinal meningiomas as a descriptive tool and surgical guide.

    PubMed

    Bayoumi, Ahmed B; Laviv, Yosef; Yokus, Burhan; Efe, Ibrahim E; Toktas, Zafer Orkun; Kilic, Turker; Demir, Mustafa K; Konya, Deniz; Kasper, Ekkehard M

    2017-11-01

    1) To provide neurosurgeons and radiologists with a new quantitative and anatomical method to describe spinal meningiomas (SM) consistently. 2) To provide a guide to the surgical approach needed and amount of bony resection required based on the proposed classification. 3) To report the distribution of our 58 cases of SM over different Stages and Subtypes in correlation to the surgical treatment needed for each case. 4) To briefly review the literature on the rare non-conventional surgical corridors to resect SM. We reviewed the literature to report on previously published cohorts and classifications used to describe the location of the tumor inside the spinal canal. We reviewed the cases that were published prior showing non-conventional surgical approaches to resect spinal meningiomas. We proposed our classification system composed of Staging based on maximal cross-sectional surface area of tumor inside canal, Typing based on number of quadrants occupied by tumor and Subtyping based on location of the tumor bulk to spinal cord. Extradural and extra-spinal growth were also covered by our classification. We then applied it retrospectively on our 58 cases. 12 articles were published illustrating overlapping terms to describe spinal meningiomas. Another 7 articles were published reporting on 23 cases of anteriorly located spinal meningiomas treated with approaches other than laminectomies/laminoplasties. 4 Types, 9 Subtypes and 4 Stages were described in our Classification System. In our series of 58 patients, no midline anterior type was represented. Therefore, all our cases were treated by laminectomies or laminoplasties (with/without facetectomies) except a case with a paraspinal component where a costotransversectomy was needed. Spinal meningiomas can be radiologically described in a precise fashion. Selection of surgical corridor depends mainly on location of tumor bulk inside canal. Copyright © 2017 Elsevier B.V. All rights reserved.

  8. "Life without nuclear power": A nuclear plant retirement formulation model and guide based on economics. San Onofre Nuclear Generating Station case: Economic impacts and reliability considerations leading to plant retirement

    NASA Astrophysics Data System (ADS)

    Wasko, Frank

    Traditionally, electric utilities have been slow to change and very bureaucratic in nature. This culture, in and of itself, has now contributed to a high percentage of United States electric utilities operating uneconomical nuclear plants (Crooks, 2014). The economic picture behind owning and operating United States nuclear plants is less than favorable for many reasons including rising fuel, capital and operating costs (EUCG, 2012). This doctoral dissertation is specifically focused on life without nuclear power. The purpose of this dissertation is to create a model and guide that will provide electric utilities who currently operate or will operate uneconomical nuclear plants the opportunity to economically assess whether or not their nuclear plant should be retired. This economic assessment and stakeholder analysis will provide local government, academia and communities the opportunity to understand how Southern California Edison (SCE) embraced system upgrade import and "voltage support" opportunities to replace "base load" generation from San Onofre Nuclear Generating Station (SONGS) versus building new replacement generation facilities. This model and guide will help eliminate the need to build large replacement generation units as demonstrated in the SONGS case analysis. The application of The Nuclear Power Retirement Model and Guide will provide electric utilities with economic assessment parameters and an evaluation assessment progression needed to better evaluate when an uneconomical nuclear plant should be retired. It will provide electric utilities the opportunity to utilize sound policy, planning and development skill sets when making this difficult decision. There are currently 62 nuclear power plants (with 100 nuclear reactors) operating in the United States (EIA, 2014). From this group, 38 are at risk of early retirement based on the work of Cooper (2013). As demonstrated in my model, 35 of the 38 nuclear power plants qualify to move to the economic assessment review and then on to the stakeholder cost benefit analysis (if model qualifications are met) leading to a final plant retirement decision. This application via the model and guide, in turn, will lead electric utilities to explore system upgrade import opportunities and mitigation measures versus building new replacement generation facilities. United States nuclear reactors are licensed for 40 years with a 20 year extension available prior to the expiration date (EIA, 2013). Since late 2012, electric power companies have announced the early retirement of four uneconomical nuclear power plants while other studies have indicated that as many as 70 percent of United States nuclear power plants are potentially at risk for early retirement (Crooks, 2014 and Cooper, 2013). A high percentage of these aforementioned nuclear plants have operating licenses that will not expire until 2030 and beyond. Thus, for the most part, replacement power contingency planning has not been initiated for these plants or is still in preliminary stages. The recent nuclear plant retirements are the first since 1998 (EIA, 2013). Decisions to retire the plants involved concerns over maintenance and repair costs as well as declining profitability (EIA, 2013). In addition, the Energy Information Administration (2010-2012) released data that demonstrated that the worst 25 percent of United States nuclear plants are far more expensive to operate and generate electricity than new gas plants. It is equally important to understand and explain the economic and power replacement implications to both ratepayers and end-users. A SONGS case study analysis will review the economic, operational and political challenges that SCE faced leading to the retirement decision of SONGS. As preface to the case study, replacement steam generators (RSGs) were installed in Unit 2 in 2009 and in Unit 3 in 2010. In January 2012, while Unit 2 was down for routine maintenance, a small leak was discovered inside a steam generator in Unit 3. Because of the situation, both units remained shut down to evaluate the cause of the leakage and to make repairs. SCE submitted plans to the Nuclear Regulatory Commission (NRC) to re-start Unit 2 at reduced power. However, concerns over the length of the review process and the high costs associated with steam generator repairs led SCE to retire both reactors (SCE SONGS Fact Sheets, 2012-2013). Finally, collaborative resource power replacement planning is needed more than ever as nuclear facilities in the United States are now being retired for economic related reasons (Crooks, 2014). This collaborative power replacement process and implementation must encompass all relevant stakeholders including state grid operators, ratepayers, shareholders and the electric utility company.

  9. 78 FR 63517 - Control of Ferrite Content in Stainless Steel Weld Metal

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-24

    ...The U.S. Nuclear Regulatory Commission (NRC) is issuing a revision to Regulatory Guide (RG) 1.31, ``Control of Ferrite Content in Stainless Steel Weld Metal.'' This guide (Revision 4) describes a method that the NRC staff considers acceptable for controlling ferrite content in stainless steel weld metal. It updates the guide to remove references to outdated standards and to remove an appendix that has been incorporated into relevant specifications.

  10. A Teacher's Guide for the Environmental Impact of Electrical Power Generation: Nuclear and Fossil. A Minicourse for Secondary Schools and Adult Education. Teacher's Guide.

    ERIC Educational Resources Information Center

    McDermott, John J., Ed.

    According to this guide, the major goal of this minicourse, developed for secondary and adult education, is to have the student gather pertinent information relative to the generation of electrical energy and to draw his own conclusions concerning the need for this energy supply. If in his mind such a need exists, he should make a judgment as to…

  11. Hedge math: Theoretical limits on minimum stockpile size across nuclear hedging strategies

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lafleur, Jarret Marshall; Roesler, Alexander W.

    2016-09-01

    In June 2013, the Department of Defense published a congressionally mandated, unclassified update on the U.S. Nuclear Employment Strategy. Among the many updates in this document are three key ground rules for guiding the sizing of the non-deployed U.S. nuclear stockpile. Furthermore, these ground rules form an important and objective set of criteria against which potential future stockpile hedging strategies can be evaluated.

  12. Export Control Guide: Loose Parts Monitoring Systems for Nuclear Power Plants

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Langenberg, Donald W.

    2012-12-01

    This report describes a typical LPMS, emphasizing its application to the RCS of a modern NPP. The report also examines the versatility of AE monitoring technology by describing several nuclear applications other than loose parts monitoring, as well as some non-nuclear applications. In addition, LPMS implementation requirements are outlined, and LPMS suppliers are identified. Finally, U.S. export controls applicable to LPMSs are discussed.

  13. Detailed requirements for a next generation nuclear data structure.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Brown, D.

    2016-07-05

    This document attempts to compile the requirements for the top-levels of a hierarchical arrangement of nuclear data such as found in the ENDF format. This set of requirements will be used to guide the development of a new data structure to replace the legacy ENDF format.

  14. A PROTOTYPE MANUAL ON CIVIL DEFENSE ASPECTS OF WATERWORKS OPERATIONS

    DTIC Science & Technology

    survival and recovery in the event of a nuclear war; (2) to stimulate and assist water utilities i developing emergency plans to cope with a nuclear ... disaster ; (3) to provide a procedural guide for restoration and for training personnel in postattack emergency repair procedures, recovery techniques, and safety measures.

  15. 77 FR 50720 - Test Documentation for Digital Computer Software Used in Safety Systems of Nuclear Power Plants

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-22

    ... NUCLEAR REGULATORY COMMISSION [NRC-2012-0195] Test Documentation for Digital Computer Software...) is issuing for public comment draft regulatory guide (DG), DG-1207, ``Test Documentation for Digital... practices for test documentation for software and computer systems as described in the Institute of...

  16. Resource Letter PD-1 on Particle Detectors

    ERIC Educational Resources Information Center

    Trower, W. Peter

    1970-01-01

    Intended to guide college physicists to literature on nuclear and sub-nuclear particle detectors. The paper contains a discussion of (1) interactions of particles with matter and (2) individual particle detectors, each section being followed by an annotated bibliography of selected reference materials. Rankings are given to the articles on the…

  17. 77 FR 63343 - Biweekly Notice: Applications and Amendments to Facility Operating Licenses and Combined Licenses...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-16

    ... PWR [Pressurized-Water Reactor] Steam Generator Tubes'' (Reference 32) and [Nuclear Energy Institute... maintains the required structural margins of the SG tubes for both normal and accident conditions. Nuclear Energy Institute 97-06, ``Steam Generator Program Guidelines'' (Reference 8), and NRC Regulatory Guide 1...

  18. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Weimar, Mark R.; Daly, Don S.; Wood, Thomas W.

    Both nuclear power and nuclear weapons programs should have (related) economic signatures which are detectible at some scale. We evaluated this premise in a series of studies using national economic input/output (IO) data. Statistical discrimination models using economic IO tables predict with a high probability whether a country with an unknown predilection for nuclear weapons proliferation is in fact engaged in nuclear power development or nuclear weapons proliferation. We analyzed 93 IO tables, spanning the years 1993 to 2005 for 37 countries that are either members or associates of the Organization for Economic Cooperation and Development (OECD). The 2009 OECDmore » input/output tables featured 48 industrial sectors based on International Standard Industrial Classification (ISIC) Revision 3, and described the respective economies in current country-of-origin valued currency. We converted and transformed these reported values to US 2005 dollars using appropriate exchange rates and implicit price deflators, and addressed discrepancies in reported industrial sectors across tables. We then classified countries with Random Forest using either the adjusted or industry-normalized values. Random Forest, a classification tree technique, separates and categorizes countries using a very small, select subset of the 2304 individual cells in the IO table. A nation’s efforts in nuclear power, be it for electricity or nuclear weapons, are an enterprise with a large economic footprint -- an effort so large that it should discernibly perturb coarse country-level economics data such as that found in yearly input-output economic tables. The neoclassical economic input-output model describes a country’s or region’s economy in terms of the requirements of industries to produce the current level of economic output. An IO table row shows the distribution of an industry’s output to the industrial sectors while a table column shows the input required of each industrial sector by a given industry.« less

  19. Float level switch for a nuclear power plant containment vessel

    DOEpatents

    Powell, J.G.

    1993-11-16

    This invention is a float level switch used to sense rise or drop in water level in a containment vessel of a nuclear power plant during a loss of coolant accident. The essential components of the device are a guide tube, a reed switch inside the guide tube, a float containing a magnetic portion that activates a reed switch, and metal-sheathed, ceramic-insulated conductors connecting the reed switch to a monitoring system outside the containment vessel. Special materials and special sealing techniques prevent failure of components and allow the float level switch to be connected to a monitoring system outside the containment vessel. 1 figures.

  20. Float level switch for a nuclear power plant containment vessel

    DOEpatents

    Powell, James G.

    1993-01-01

    This invention is a float level switch used to sense rise or drop in water level in a containment vessel of a nuclear power plant during a loss of coolant accident. The essential components of the device are a guide tube, a reed switch inside the guide tube, a float containing a magnetic portion that activates a reed switch, and metal-sheathed, ceramic-insulated conductors connecting the reed switch to a monitoring system outside the containment vessel. Special materials and special sealing techniques prevent failure of components and allow the float level switch to be connected to a monitoring system outside the containment vessel.

  1. Workshop Physics Activity Guide, Module 3: Heat Temperature and Nuclear Radiation, Thermodynamics, Kinetic Theory, Heat Engines, Nuclear Decay, and Random Monitoring (Units 16 - 18 & 28)

    NASA Astrophysics Data System (ADS)

    Laws, Priscilla W.

    2004-05-01

    The Workshop Physics Activity Guide is a set of student workbooks designed to serve as the foundation for a two-semester calculus-based introductory physics course. It consists of 28 units that interweave text materials with activities that include prediction, qualitative observation, explanation, equation derivation, mathematical modeling, quantitative experiments, and problem solving. Students use a powerful set of computer tools to record, display, and analyze data, as well as to develop mathematical models of physical phenomena. The design of many of the activities is based on the outcomes of physics education research.

  2. piRNA-guided slicing of transposon transcripts enforces their transcriptional silencing via specifying the nuclear piRNA repertoire.

    PubMed

    Senti, Kirsten-André; Jurczak, Daniel; Sachidanandam, Ravi; Brennecke, Julius

    2015-08-15

    PIWI clade Argonaute proteins silence transposon expression in animal gonads. Their target specificity is defined by bound ∼23- to 30-nucleotide (nt) PIWI-interacting RNAs (piRNAs) that are processed from single-stranded precursor transcripts via two distinct pathways. Primary piRNAs are defined by the endonuclease Zucchini, while biogenesis of secondary piRNAs depends on piRNA-guided transcript cleavage and results in piRNA amplification. Here, we analyze the interdependencies between these piRNA biogenesis pathways in developing Drosophila ovaries. We show that secondary piRNA-guided target slicing is the predominant mechanism that specifies transcripts—including those from piRNA clusters—as primary piRNA precursors and defines the spectrum of Piwi-bound piRNAs in germline cells. Post-transcriptional silencing in the cytoplasm therefore enforces nuclear transcriptional target silencing, which ensures the tight suppression of transposons during oogenesis. As target slicing also defines the nuclear piRNA pool during mouse spermatogenesis, our findings uncover an unexpected conceptual similarity between the mouse and fly piRNA pathways. © 2015 Senti et al.; Published by Cold Spring Harbor Laboratory Press.

  3. The Warning System in Disaster Situations: A Selective Analysis.

    DTIC Science & Technology

    DISASTERS, *WARNING SYSTEMS), CIVIL DEFENSE, SOCIAL PSYCHOLOGY, REACTION(PSYCHOLOGY), FACTOR ANALYSIS, CLASSIFICATION, STATISTICAL DATA, TIME ... MANAGEMENT PLANNING AND CONTROL, DAMAGE, CONTROL SYSTEMS, THREAT EVALUATION, DECISION MAKING, DATA PROCESSING, COMMUNICATION SYSTEMS, NUCLEAR EXPLOSIONS

  4. A thyroid nodule classification method based on TI-RADS

    NASA Astrophysics Data System (ADS)

    Wang, Hao; Yang, Yang; Peng, Bo; Chen, Qin

    2017-07-01

    Thyroid Imaging Reporting and Data System(TI-RADS) is a valuable tool for differentiating the benign and the malignant thyroid nodules. In clinic, doctors can determine the extent of being benign or malignant in terms of different classes by using TI-RADS. Classification represents the degree of malignancy of thyroid nodules. TI-RADS as a classification standard can be used to guide the ultrasonic doctor to examine thyroid nodules more accurately and reliably. In this paper, we aim to classify the thyroid nodules with the help of TI-RADS. To this end, four ultrasound signs, i.e., cystic and solid, echo pattern, boundary feature and calcification of thyroid nodules are extracted and converted into feature vectors. Then semi-supervised fuzzy C-means ensemble (SS-FCME) model is applied to obtain the classification results. The experimental results demonstrate that the proposed method can help doctors diagnose the thyroid nodules effectively.

  5. Radiation protection issues on preparedness and response for a severe nuclear accident: experiences of the Fukushima accident.

    PubMed

    Homma, T; Takahara, S; Kimura, M; Kinase, S

    2015-06-01

    Radiation protection issues on preparedness and response for a severe nuclear accident are discussed in this paper based on the experiences following the accident at Fukushima Daiichi nuclear power plant. The criteria for use in nuclear emergencies in the Japanese emergency preparedness guide were based on the recommendations of International Commission of Radiological Protection (ICRP) Publications 60 and 63. Although the decision-making process for implementing protective actions relied heavily on computer-based predictive models prior to the accident, urgent protective actions, such as evacuation and sheltering, were implemented effectively based on the plant conditions. As there were no recommendations and criteria for long-term protective actions in the emergency preparedness guide, the recommendations of ICRP Publications 103, 109, and 111 were taken into consideration in determining the temporary relocation of inhabitants of heavily contaminated areas. These recommendations were very useful in deciding the emergency protective actions to take in the early stages of the Fukushima accident. However, some suggestions have been made for improving emergency preparedness and response in the early stages of a severe nuclear accident. © The Chartered Institution of Building Services Engineers 2014.

  6. Classification of Computer-Aided Design-Computer-Aided Manufacturing Applications for the Reconstruction of Cranio-Maxillo-Facial Defects.

    PubMed

    Wauters, Lauri D J; Miguel-Moragas, Joan San; Mommaerts, Maurice Y

    2015-11-01

    To gain insight into the methodology of different computer-aided design-computer-aided manufacturing (CAD-CAM) applications for the reconstruction of cranio-maxillo-facial (CMF) defects. We reviewed and analyzed the available literature pertaining to CAD-CAM for use in CMF reconstruction. We proposed a classification system of the techniques of implant and cutting, drilling, and/or guiding template design and manufacturing. The system consisted of 4 classes (I-IV). These classes combine techniques used for both the implant and template to most accurately describe the methodology used. Our classification system can be widely applied. It should facilitate communication and immediate understanding of the methodology of CAD-CAM applications for the reconstruction of CMF defects.

  7. Classification capacity of a modular neural network implementing neurally inspired architecture and training rules.

    PubMed

    Poirazi, Panayiota; Neocleous, Costas; Pattichis, Costantinos S; Schizas, Christos N

    2004-05-01

    A three-layer neural network (NN) with novel adaptive architecture has been developed. The hidden layer of the network consists of slabs of single neuron models, where neurons within a slab--but not between slabs--have the same type of activation function. The network activation functions in all three layers have adaptable parameters. The network was trained using a biologically inspired, guided-annealing learning rule on a variety of medical data. Good training/testing classification performance was obtained on all data sets tested. The performance achieved was comparable to that of SVM classifiers. It was shown that the adaptive network architecture, inspired from the modular organization often encountered in the mammalian cerebral cortex, can benefit classification performance.

  8. CNN Newsroom Classroom Guides. October 1999.

    ERIC Educational Resources Information Center

    Cable News Network, Atlanta, GA.

    These guides, designed to accompany the daily Cable News Network (CNN) Newsroom broadcasts for October 1-29, 1999, provide program rundowns, suggestions for class activities and discussion, links to relevant World Wide Web sites, and a list of related news terms. Top stories include: nuclear accident in Japan (October 1); debate over the nuclear…

  9. 77 FR 33253 - Regulatory Guide 8.24, Revision 2, Health Physics Surveys During Enriched Uranium-235 Processing...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-05

    ... NUCLEAR REGULATORY COMMISSION [NRC-2010-0115] Regulatory Guide 8.24, Revision 2, Health Physics..., ``Health Physics Surveys During Enriched Uranium-235 Processing and Fuel Fabrication'' was issued with a... specifically with the following aspects of an acceptable occupational health physics program that are closely...

  10. 78 FR 37848 - ASME Code Cases Not Approved for Use

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-24

    ...The U.S. Nuclear Regulatory Commission (NRC) is issuing for public comment draft regulatory guide (DG), DG-1233, ``ASME Code Cases not Approved for Use.'' This regulatory guide lists the American Society of Mechanical Engineers (ASME) Code Cases that the NRC has determined not to be acceptable for use on a generic basis.

  11. 77 FR 40385 - Withdrawal of Regulatory Guide 7.3; Procedures for Picking Up and Receiving Packages of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-09

    ... Picking Up and Receiving Packages of Radioactive Material AGENCY: Nuclear Regulatory Commission. ACTION... Receiving Packages of Radioactive Material.'' The RG is being withdrawn because it is outdated and the..., ``Administrative Guide for Verifying Compliance with Packaging Requirements for Shipment and Receipt of Radioactive...

  12. 75 FR 45172 - Withdrawal of Regulatory Guides 3.44 and 3.49

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-02

    ... Format and Content for the Safety Analysis Report for an Independent Spent Fuel Storage Installation... on the format and content of the safety analysis report that is required as part of an application to...: Nuclear Regulatory Commission. ACTION: Withdrawal of Regulatory Guide 3.44, ``Standard Format and Content...

  13. Import routes and nuclear functions of Argonaute and other small RNA-silencing proteins.

    PubMed

    Schraivogel, Daniel; Meister, Gunter

    2014-09-01

    Small RNAs are important regulators of gene expression in many different organisms. Nuclear and cytoplasmic biogenesis enzymes generate functional small RNAs from double-stranded (ds) or single-stranded (ss) RNA precursors, and mature small RNAs are loaded into Argonaute proteins. In the cytoplasm, small RNAs guide Argonaute proteins to complementary RNAs leading to cleavage of these targets, translational silencing, or mRNA decay. In the nucleus Argonaute proteins engage in transcriptional silencing processes such as epigenetic silencing of repetitive elements at the chromatin level. During the past few years many novel functions of small RNA-guided gene silencing proteins in the nucleus have been reported. However, their specific import routes are largely unknown. In this review we summarize the current knowledge on nuclear transport routes that Argonaute and other RNA-silencing proteins take to carry out their various functions in the nucleus. Copyright © 2014 Elsevier Ltd. All rights reserved.

  14. DOE Office of Scientific and Technical Information (OSTI.GOV)

    MITCHELL,GERRY W.; LONGLEY,SUSAN W.; PHILBIN,JEFFREY S.

    This Safety Analysis Report (SAR) is prepared in compliance with the requirements of DOE Order 5480.23, Nuclear Safety Analysis Reports, and has been written to the format and content guide of DOE-STD-3009-94 Preparation Guide for U. S. Department of Energy Nonreactor Nuclear Safety Analysis Reports. The Hot Cell Facility is a Hazard Category 2 nonreactor nuclear facility, and is operated by Sandia National Laboratories for the Department of Energy. This SAR provides a description of the HCF and its operations, an assessment of the hazards and potential accidents which may occur in the facility. The potential consequences and likelihood ofmore » these accidents are analyzed and described. Using the process and criteria described in DOE-STD-3009-94, safety-related structures, systems and components are identified, and the important safety functions of each SSC are described. Additionally, information which describes the safety management programs at SNL are described in ancillary chapters of the SAR.« less

  15. High Pressure Coolant Injection (HPCI) System Risk-Based Inspection Guide for Browns Ferry Nuclear Power Station

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wong, S.; DiBiasio, A.; Gunther, W.

    1993-09-01

    The High Pressure Coolant Injection (HPCI) system has been examined from a risk perspective. A System Risk-Based Inspection Guide (S-RIG) has been developed as an aid to HPCI system inspections at the Browns Ferry Nuclear Power Plant, Units 1, 2 and 3. The role of. the HPCI system in mitigating accidents is discussed in this S-RIG, along with insights on identified risk-based failure modes which could prevent proper operation of the system. The S-RIG provides a review of industry-wide operating experience, including plant-specific illustrative examples to augment the PRA and operational considerations in identifying a catalogue of basic PRA failuremore » modes for the HPCI system. It is designed to be used as a reference for routine inspections, self-initiated safety system functional inspections (SSFIs), and the evaluation of risk significance of component failures at the nuclear power plant.« less

  16. 77 FR 60478 - Control of Ferrite Content in Stainless Steel Weld Metal

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-03

    ...The U.S. Nuclear Regulatory Commission (NRC or the Commission) is issuing for public comment draft regulatory guide (DG), DG-1279, ``Control of Ferrite Content in Stainless Steel Weld Metal.'' This guide describes a method that the NRC staff considers acceptable for controlling ferrite content in stainless steel weld metal. Revision 4 updates the guide to remove references to outdated standards and to remove an appendix that has been incorporated into relevant specifications.

  17. Program Office Guide to Ada. Edition 1

    DTIC Science & Technology

    1986-09-17

    publication. MARK V. ZIEMBA , 2Lt, USAF Project Officer, Software Engineering Tools & Methods ARTHUR G. DECELLES, Capt, USAF Program Manager, Computer...UNLIMITED G3 SAME AS RPT D DTIC USERS 21 ABSTRACT SECURITY CLASSIFICATION UNCLASSIFIED 22a. NAME OF RESPONSIBLE INDIVIDUAL M.V. Ziemba

  18. CVAE-VEH Horticulture Course Outline.

    ERIC Educational Resources Information Center

    Texas A and M Univ., College Station. Vocational Instructional Services.

    This curriculum guide consists of 14 units for use in teaching a high school level horticulture course. Covered in the individual units are the following topics: opportunities in horticultural occupations; plant classification and identification; structures and equipment used in producing greenhouse, ornamental, and nursery plants; greenhouse…

  19. Atomic papers: a citizen's guide to selected books and articles on the bomb, the arms race, nuclear power, the peace movement, and related issues

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Burns, G.

    This bibliography, updated from an earlier 1947 printing, is divided into 18 separate areas. It will allow the reader to identify books and recent journal and magazine articles on the panoply of nuclear issues. It assumed that better information enables more-effective involvement in the effort to secure real peace, and not the dubious peace achieved through nuclear terror.

  20. A Guide to Nuclear Weapons Phenomena and Effects Literature

    DTIC Science & Technology

    1984-10-31

    and Disarmament Agency. An article entitled "Limited Nuclear War" in Scientific American (Reference ECE-14) is also of interest because of its rela... Sistems and the Aemosphere’-BCj=9. 43 Personne l; .-EP)- / 47 Civilian .S’ector and the .Environment, (ECE) 50 5 SPECIAL REFERENCE MATERIALS (R) ’<ൾ...approximations. DNA has sponsored the development of software for scientific and military applications of nuclear weapon phenomena and effects information

  1. Atlas-guided prostate intensity modulated radiation therapy (IMRT) planning.

    PubMed

    Sheng, Yang; Li, Taoran; Zhang, You; Lee, W Robert; Yin, Fang-Fang; Ge, Yaorong; Wu, Q Jackie

    2015-09-21

    An atlas-based IMRT planning technique for prostate cancer was developed and evaluated. A multi-dose atlas was built based on the anatomy patterns of the patients, more specifically, the percent distance to the prostate and the concaveness angle formed by the seminal vesicles relative to the anterior-posterior axis. A 70-case dataset was classified using a k-medoids clustering analysis to recognize anatomy pattern variations in the dataset. The best classification, defined by the number of classes or medoids, was determined by the largest value of the average silhouette width. Reference plans from each class formed a multi-dose atlas. The atlas-guided planning (AGP) technique started with matching the new case anatomy pattern to one of the reference cases in the atlas; then a deformable registration between the atlas and new case anatomies transferred the dose from the atlas to the new case to guide inverse planning with full automation. 20 additional clinical cases were re-planned to evaluate the AGP technique. Dosimetric properties between AGP and clinical plans were evaluated. The classification analysis determined that the 5-case atlas would best represent anatomy patterns for the patient cohort. AGP took approximately 1 min on average (corresponding to 70 iterations of optimization) for all cases. When dosimetric parameters were compared, the differences between AGP and clinical plans were less than 3.5%, albeit some statistical significances observed: homogeneity index (p  >  0.05), conformity index (p  <  0.01), bladder gEUD (p  <  0.01), and rectum gEUD (p  =  0.02). Atlas-guided treatment planning is feasible and efficient. Atlas predicted dose can effectively guide the optimizer to achieve plan quality comparable to that of clinical plans.

  2. 78 FR 47012 - Developing Software Life Cycle Processes Used in Safety Systems of Nuclear Power Plants

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-02

    ... NUCLEAR REGULATORY COMMISSION [NRC-2012-0195] Developing Software Life Cycle Processes Used in... revised regulatory guide (RG), revision 1 of RG 1.173, ``Developing Software Life Cycle Processes for... Developing a Software Project Life Cycle Process,'' issued 2006, with the clarifications and exceptions as...

  3. Dialogue: A Teaching Guide to Nuclear Issues.

    ERIC Educational Resources Information Center

    Educators for Social Responsibility, Cambridge, MA.

    Materials in this manual are designed to help educators raise the issue of nuclear war through a "day of dialog" on the subject. There are seven sections. Section 1 contains a project reationale; suggestions for implementation; methods for meeting resistance; tips for schoolwide, parent-teacher, and community discussion; uses of the media; and…

  4. 75 FR 54918 - Draft Regulatory Guide, DG-1247, “Design-Basis Hurricane and Hurricane Missiles for Nuclear Power...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-09

    ... that the staff uses in evaluating specific problems or postulated accidents, and data that the staff... turbine missiles. NUREG/CR 7004 is the technical basis for regulatory guidance on design-basis hurricane... hurricane wind speeds for new nuclear power plants. [[Page 54919

  5. Teaching about Conflict, Nuclear War and the Future.

    ERIC Educational Resources Information Center

    Zola, John; Sieck, Reny

    Designed for teachers of students in grades 5-12, the guide provides over 25 lesson plans and 45 student handouts for teaching units on conflict, nuclear war, and future studies. In the first unit, students define conflict, learn conflict-related vocabulary, illustrate knowledge of conflict types through the use of cartoons, recognize common…

  6. 76 FR 40943 - Notice of Issuance of Regulatory Guide

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-12

    ..., Revision 3, ``Criteria for Use of Computers in Safety Systems of Nuclear Power Plants.'' FOR FURTHER..., ``Criteria for Use of Computers in Safety Systems of Nuclear Power Plants,'' was issued with a temporary... Fuel Reprocessing Plants,'' to 10 CFR part 50 with regard to the use of computers in safety systems of...

  7. 76 FR 52715 - Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS Subcommittee on Regulatory...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-23

    ... review Draft Final Regulatory Guide (RG) 1.93, ``Availability of Electric Power Sources,'' Revision 1 and new Draft Final RG 1.218, ``Condition Monitoring Techniques for Electric Cables Used in Nuclear Power... NUCLEAR REGULATORY COMMISSION Advisory Committee on Reactor Safeguards (ACRS); Meeting of the ACRS...

  8. The Harnessed Atom: Nuclear Energy & Electricity.

    ERIC Educational Resources Information Center

    Department of Energy, Washington, DC. Nuclear Energy Office.

    This document is part of a nuclear energy curriculum designed for grades six through eight. The complete kit includes a written text, review exercises, activities for the students, and a teachers guide. The 19 lessons in the curriculum are divided into four units including: (1) "Energy and Electricity"; (2) "Understanding Atoms and Radiation"; (3)…

  9. 76 FR 43356 - Evaluations of Explosions Postulated To Occur at Nearby Facilities and on Transportation Routes...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-20

    ... the ``Regulatory Guides'' collection of the NRC's Library at http://www.nrc.gov/reading-rm/doc... NUCLEAR REGULATORY COMMISSION [NRC-2011-0152] Evaluations of Explosions Postulated To Occur at..., ``Evaluations of Explosions Postulated to Occur at Nearby Facilities and on Transportation Routes Near Nuclear...

  10. COL Application Content Guide for HTGRs: Revision to RG 1.206, Part 1 - Status Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wayne Moe

    2012-08-01

    A combined license (COL) application is required by the Nuclear Regulatory Commission (NRC) for all proposed nuclear plants. The information requirements for a COL application are set forth in 10 CFR 52.79, “Contents of Applications; Technical Information in Final Safety Analysis Report.” An applicant for a modular high temperature gas-cooled reactor (HTGR) must develop and submit for NRC review and approval a COL application which conforms to these requirements. The technical information necessary to allow NRC staff to evaluate a COL application and resolve all safety issues related to a proposed nuclear plant is detailed and comprehensive. To this, Regulatorymore » Guide (RG) 1.206, “Combined License Applications for Nuclear Power Plants” (LWR Edition), was developed to assist light water reactor (LWR) applicants in incorporating and effectively formatting required information for COL application review (Ref. 1). However, the guidance prescribed in RG 1.206 presumes a LWR design proposal consistent with the systems and functions associated with large LWR power plants currently operating under NRC license.« less

  11. Decomposition of the Seismic Source Using Numerical Simulations and Observations of Nuclear Explosions

    DTIC Science & Technology

    2017-05-31

    SUBJECT TERMS nonlinear finite element calculations, nuclear explosion monitoring, topography 16. SECURITY CLASSIFICATION OF: 17. LIMITATION OF ABSTRACT 18...3D North Korea calculations........ Figure 6. The CRAM 3D finite element outer grid (left) is rectangular......................... Figure 7. Stress...Figure 6. The CRAM 3D finite element outer grid (left) is rectangular. The inner grid (center) is shaped to match the shape of the explosion shock wave

  12. A Review of the Air Chemistry and Relevant Parameters for the Modelling of the Nuclear Induced Lightning.

    DTIC Science & Technology

    1984-05-31

    MARK %C-, S UNCLASSIFIED 2o SEC. - l R Y C.-ASSF.CAT’ION...1971). 31. C. S . Lakshminarasimha and J. Lucas, J. Phys D 10,313 (1977). 32. R. W. Crompton, L. G. H. Huxley and D. J. Sutton , Proc. R. Soc. London...APR EDITION OF I.AN 73 S OBSOLE’E SECURITY CLASSIFICATION I1F THIS PAI,E %.. % %% " -6 % * U ,4 % 4 SECURITY CLASSIFICATION OF THIS PAGE 11.

  13. Round Cell Tumors: Classification and Immunohistochemistry.

    PubMed

    Sharma, Shweta; Kamala, R; Nair, Divya; Ragavendra, T Raju; Mhatre, Swapnil; Sabharwal, Robin; Choudhury, Basanta Kumar; Rana, Vivek

    2017-01-01

    Round cell tumors as the name suggest are comprised round cells with increased nuclear-cytoplasmic ratio. This group of tumor includes entities such as peripheral neuroectodermal tumor, rhabdomyosarcoma, synovial sarcoma, non-Hodgkin's lymphoma, neuroblastoma, hepatoblastoma, Wilms' tumor, and desmoplastic small round cell tumor. These round cells tumors are characterized by typical histological pattern, immunohistochemical, and electron microscopic features that can help in differential diagnosis. The present article describes the classification and explains the histopathology and immunohistochemistry of some important round cell tumors.

  14. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sanfilippo, Antonio P.; Chikkagoudar, Satish

    We describe an approach to analyzing trade data which uses clustering to detect similarities across shipping manifest records, classification to evaluate clustering results and categorize new unseen shipping data records, and visual analytics to provide to support situation awareness in dynamic decision making to monitor and warn against the movement of radiological threat materials through search, analysis and forecasting capabilities. The evaluation of clustering results through classification and systematic inspection of the clusters show the clusters have strong semantic cohesion and offer novel ways to detect transactions related to nuclear smuggling.

  15. Nonlinear, non-stationary image processing technique for eddy current NDE

    NASA Astrophysics Data System (ADS)

    Yang, Guang; Dib, Gerges; Kim, Jaejoon; Zhang, Lu; Xin, Junjun; Udpa, Lalita

    2012-05-01

    Automatic analysis of eddy current (EC) data has facilitated the analysis of large volumes of data generated in the inspection of steam generator tubes in nuclear power plants. The traditional procedure for analysis of EC data includes data calibration, pre-processing, region of interest (ROI) detection, feature extraction and classification. Accurate ROI detection has been enhanced by pre-processing, which involves reducing noise and other undesirable components as well as enhancing defect indications in the raw measurement. This paper presents the Hilbert-Huang Transform (HHT) for feature extraction and support vector machine (SVM) for classification. The performance is shown to significantly better than the existing rule based classification approach used in industry.

  16. 21 CFR 886.1870 - Stereoscope.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...-dimensional appearance of solidity and relief. It is intended to measure the angle of strabismus (eye muscle deviation), evaluate binocular vision (usage of both eyes to see), and guide a patient's corrective exercises of eye muscles. (b) Classification. Class I (general controls). The AC-powered device and the...

  17. 21 CFR 886.1870 - Stereoscope.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...-dimensional appearance of solidity and relief. It is intended to measure the angle of strabismus (eye muscle deviation), evaluate binocular vision (usage of both eyes to see), and guide a patient's corrective exercises of eye muscles. (b) Classification. Class I (general controls). The AC-powered device and the...

  18. Ornamental and Turfgrass Pest Control.

    ERIC Educational Resources Information Center

    Arizona Univ., Tucson. Cooperative Extension Service.

    This guide provides basic information regarding the utilization and application of pesticides. Classifications are given for herbicides, insecticides, fungicides, and fumigants with indications of how each works. Types of application and appropriate equipment are discussed. Safety to both the applicator and the environment are stressed. A glossary…

  19. 14 CFR 1203.401 - Effect of open publication.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 5 2011-01-01 2010-01-01 true Effect of open publication. 1203.401 Section 1203.401 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION INFORMATION SECURITY PROGRAM Guides for Original Classification § 1203.401 Effect of open publication. Public disclosure...

  20. 14 CFR 1203.401 - Effect of open publication.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 5 2012-01-01 2012-01-01 false Effect of open publication. 1203.401 Section 1203.401 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION INFORMATION SECURITY PROGRAM Guides for Original Classification § 1203.401 Effect of open publication. Public disclosure...

  1. 14 CFR 1203.401 - Effect of open publication.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Effect of open publication. 1203.401 Section 1203.401 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION INFORMATION SECURITY PROGRAM Guides for Original Classification § 1203.401 Effect of open publication. Public disclosure...

  2. 14 CFR 1203.401 - Effect of open publication.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 5 2013-01-01 2013-01-01 false Effect of open publication. 1203.401 Section 1203.401 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION INFORMATION SECURITY PROGRAM Guides for Original Classification § 1203.401 Effect of open publication. Public disclosure...

  3. Neural-Fuzzy model Based Steel Pipeline Multiple Cracks Classification

    NASA Astrophysics Data System (ADS)

    Elwalwal, Hatem Mostafa; Mahzan, Shahruddin Bin Hj.; Abdalla, Ahmed N.

    2017-10-01

    While pipes are cheaper than other means of transportation, this cost saving comes with a major price: pipes are subject to cracks, corrosion etc., which in turn can cause leakage and environmental damage. In this paper, Neural-Fuzzy model for multiple cracks classification based on Lamb Guide Wave. Simulation results for 42 sample were collected using ANSYS software. The current research object to carry on the numerical simulation and experimental study, aiming at finding an effective way to detection and the localization of cracks and holes defects in the main body of pipeline. Considering the damage form of multiple cracks and holes which may exist in pipeline, to determine the respective position in the steel pipe. In addition, the technique used in this research a guided lamb wave based structural health monitoring method whereas piezoelectric transducers will use as exciting and receiving sensors by Pitch-Catch method. Implementation of simple learning mechanism has been developed specially for the ANN for fuzzy the system represented.

  4. Automated Patent Categorization and Guided Patent Search using IPC as Inspired by MeSH and PubMed.

    PubMed

    Eisinger, Daniel; Tsatsaronis, George; Bundschus, Markus; Wieneke, Ulrich; Schroeder, Michael

    2013-04-15

    Document search on PubMed, the pre-eminent database for biomedical literature, relies on the annotation of its documents with relevant terms from the Medical Subject Headings ontology (MeSH) for improving recall through query expansion. Patent documents are another important information source, though they are considerably less accessible. One option to expand patent search beyond pure keywords is the inclusion of classification information: Since every patent is assigned at least one class code, it should be possible for these assignments to be automatically used in a similar way as the MeSH annotations in PubMed. In order to develop a system for this task, it is necessary to have a good understanding of the properties of both classification systems. This report describes our comparative analysis of MeSH and the main patent classification system, the International Patent Classification (IPC). We investigate the hierarchical structures as well as the properties of the terms/classes respectively, and we compare the assignment of IPC codes to patents with the annotation of PubMed documents with MeSH terms.Our analysis shows a strong structural similarity of the hierarchies, but significant differences of terms and annotations. The low number of IPC class assignments and the lack of occurrences of class labels in patent texts imply that current patent search is severely limited. To overcome these limits, we evaluate a method for the automated assignment of additional classes to patent documents, and we propose a system for guided patent search based on the use of class co-occurrence information and external resources.

  5. Automated Patent Categorization and Guided Patent Search using IPC as Inspired by MeSH and PubMed

    PubMed Central

    2013-01-01

    Document search on PubMed, the pre-eminent database for biomedical literature, relies on the annotation of its documents with relevant terms from the Medical Subject Headings ontology (MeSH) for improving recall through query expansion. Patent documents are another important information source, though they are considerably less accessible. One option to expand patent search beyond pure keywords is the inclusion of classification information: Since every patent is assigned at least one class code, it should be possible for these assignments to be automatically used in a similar way as the MeSH annotations in PubMed. In order to develop a system for this task, it is necessary to have a good understanding of the properties of both classification systems. This report describes our comparative analysis of MeSH and the main patent classification system, the International Patent Classification (IPC). We investigate the hierarchical structures as well as the properties of the terms/classes respectively, and we compare the assignment of IPC codes to patents with the annotation of PubMed documents with MeSH terms. Our analysis shows a strong structural similarity of the hierarchies, but significant differences of terms and annotations. The low number of IPC class assignments and the lack of occurrences of class labels in patent texts imply that current patent search is severely limited. To overcome these limits, we evaluate a method for the automated assignment of additional classes to patent documents, and we propose a system for guided patent search based on the use of class co-occurrence information and external resources. PMID:23734562

  6. The Energy Films Index. An Educator's Guide to Current Energy Films.

    ERIC Educational Resources Information Center

    Scherner, Sharon; And Others

    This guide cites and describes 241 films on energy. The categories are: general films on energy, conservation of energy, history of energy development, coal, electricity, food and energy, geothermal, natural gas, nuclear energy, oil/petroleum, oil shale, solar energy, tar sands, tidal energy, wind, impacts of energy, and future of energy. For each…

  7. 78 FR 55117 - Ultimate Heat Sink for Nuclear Power Plants; Draft Regulatory Guide

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-09

    ... applicants may use to implement general design criteria (GDC) that are applicable to the ultimate heat sink... only for comments received on or before this date. Although a time limit is given, comments and... published guides are encouraged at any time. ADDRESSES: You may submit comment by any of the following...

  8. Gap analysis survey: an aid in transitioning to standardized curricula for nuclear medicine technology.

    PubMed

    Bires, Angela Macci; Mason, Donna L; Gilmore, David; Pietrzyk, Carly

    2012-09-01

    This article discusses the process by which the Society of Nuclear Medicine Technology Section (SNMTS) is assisting educators as they transition to comply with the fourth edition of the Curriculum Guide for Educational Programs in Nuclear Medicine Technology. An electronic survey was sent to a list of nuclear medicine technology programs compiled by the educational division of the SNMTS. The collected data included committee member demographics, goals and objectives, conference call minutes, consultation discussions, transition examples, 4- and 2-y program curricula, and certificate program curricula. There were 56 responses to the survey. All respondents were program directors, with 3 respondents having more than one type of program, for a total of 59 programs. Of these, 19 (33.93%) were baccalaureate, 19 (28.57%) associate, and 21 (37.5%) certificate. Forty-eight respondents (85.71%) had accreditation through the Joint Review Commission on Educational Programs in Nuclear Medicine Technology, 6 (10.71%) had regional accreditation, and 2 (3.57%) were accredited through other entities. Thirteen categories of required general education courses were identified, and the existing program curricula of 9 (69.2%) courses were more than 50% compliant with the fourth edition Curriculum Guide. The fact that no measurable gap could be found within the didactic professional content across programs was due to the lack of a degree requirement and content standardization within the profession. The data indicated that the participating programs offer a minimum of 1-15 contact hours in emerging technology modalities. The required clinical hours ranged from 765 to 1,920 for degree or certificate completion. The average number of clinical hours required for all programs was 1,331.69. Standardization of the number and types of courses is needed both for current baccalaureate programs and for clinical education. This standardization will guide programs in transitioning from a certificate or associate level to the baccalaureate level. The greatest obstacle is in expanding curricula to meet the recommendations of the fourth edition Curriculum Guide. Such expansion to entry-level competency may be met by incorporating hybrid imaging courses, secondary-level courses, and equivalency courses on the basic sciences and emerging technologies.

  9. Application of time series discretization using evolutionary programming for classification of precancerous cervical lesions.

    PubMed

    Acosta-Mesa, Héctor-Gabriel; Rechy-Ramírez, Fernando; Mezura-Montes, Efrén; Cruz-Ramírez, Nicandro; Hernández Jiménez, Rodolfo

    2014-06-01

    In this work, we present a novel application of time series discretization using evolutionary programming for the classification of precancerous cervical lesions. The approach optimizes the number of intervals in which the length and amplitude of the time series should be compressed, preserving the important information for classification purposes. Using evolutionary programming, the search for a good discretization scheme is guided by a cost function which considers three criteria: the entropy regarding the classification, the complexity measured as the number of different strings needed to represent the complete data set, and the compression rate assessed as the length of the discrete representation. This discretization approach is evaluated using a time series data based on temporal patterns observed during a classical test used in cervical cancer detection; the classification accuracy reached by our method is compared with the well-known times series discretization algorithm SAX and the dimensionality reduction method PCA. Statistical analysis of the classification accuracy shows that the discrete representation is as efficient as the complete raw representation for the present application, reducing the dimensionality of the time series length by 97%. This representation is also very competitive in terms of classification accuracy when compared with similar approaches. Copyright © 2014 Elsevier Inc. All rights reserved.

  10. Computational Pathology to Discriminate Benign from Malignant Intraductal Proliferations of the Breast

    PubMed Central

    Oh, Eun-Yeong; Lerwill, Melinda F.; Brachtel, Elena F.; Jones, Nicholas C.; Knoblauch, Nicholas W.; Montaser-Kouhsari, Laleh; Johnson, Nicole B.; Rao, Luigi K. F.; Faulkner-Jones, Beverly; Wilbur, David C.; Schnitt, Stuart J.; Beck, Andrew H.

    2014-01-01

    The categorization of intraductal proliferative lesions of the breast based on routine light microscopic examination of histopathologic sections is in many cases challenging, even for experienced pathologists. The development of computational tools to aid pathologists in the characterization of these lesions would have great diagnostic and clinical value. As a first step to address this issue, we evaluated the ability of computational image analysis to accurately classify DCIS and UDH and to stratify nuclear grade within DCIS. Using 116 breast biopsies diagnosed as DCIS or UDH from the Massachusetts General Hospital (MGH), we developed a computational method to extract 392 features corresponding to the mean and standard deviation in nuclear size and shape, intensity, and texture across 8 color channels. We used L1-regularized logistic regression to build classification models to discriminate DCIS from UDH. The top-performing model contained 22 active features and achieved an AUC of 0.95 in cross-validation on the MGH data-set. We applied this model to an external validation set of 51 breast biopsies diagnosed as DCIS or UDH from the Beth Israel Deaconess Medical Center, and the model achieved an AUC of 0.86. The top-performing model contained active features from all color-spaces and from the three classes of features (morphology, intensity, and texture), suggesting the value of each for prediction. We built models to stratify grade within DCIS and obtained strong performance for stratifying low nuclear grade vs. high nuclear grade DCIS (AUC = 0.98 in cross-validation) with only moderate performance for discriminating low nuclear grade vs. intermediate nuclear grade and intermediate nuclear grade vs. high nuclear grade DCIS (AUC = 0.83 and 0.69, respectively). These data show that computational pathology models can robustly discriminate benign from malignant intraductal proliferative lesions of the breast and may aid pathologists in the diagnosis and classification of these lesions. PMID:25490766

  11. HEp-2 cell image classification method based on very deep convolutional networks with small datasets

    NASA Astrophysics Data System (ADS)

    Lu, Mengchi; Gao, Long; Guo, Xifeng; Liu, Qiang; Yin, Jianping

    2017-07-01

    Human Epithelial-2 (HEp-2) cell images staining patterns classification have been widely used to identify autoimmune diseases by the anti-Nuclear antibodies (ANA) test in the Indirect Immunofluorescence (IIF) protocol. Because manual test is time consuming, subjective and labor intensive, image-based Computer Aided Diagnosis (CAD) systems for HEp-2 cell classification are developing. However, methods proposed recently are mostly manual features extraction with low accuracy. Besides, the scale of available benchmark datasets is small, which does not exactly suitable for using deep learning methods. This issue will influence the accuracy of cell classification directly even after data augmentation. To address these issues, this paper presents a high accuracy automatic HEp-2 cell classification method with small datasets, by utilizing very deep convolutional networks (VGGNet). Specifically, the proposed method consists of three main phases, namely image preprocessing, feature extraction and classification. Moreover, an improved VGGNet is presented to address the challenges of small-scale datasets. Experimental results over two benchmark datasets demonstrate that the proposed method achieves superior performance in terms of accuracy compared with existing methods.

  12. Robust nuclear lamina-based cell classification of aging and senescent cells

    PubMed Central

    Righolt, Christiaan H.; van 't Hoff, Merel L.R.; Vermolen, Bart J.; Young, Ian T.; Raz, Vered

    2011-01-01

    Changes in the shape of the nuclear lamina are exhibited in senescent cells, as well as in cells expressing mutations in lamina genes. To identify cells with defects in the nuclear lamina we developed an imaging method that quantifies the intensity and curvature of the nuclear lamina. We show that this method accurately describes changes in the nuclear lamina. Spatial changes in nuclear lamina coincide with redistribution of lamin A proteins and local reduction in protein mobility in senescent cell. We suggest that local accumulation of lamin A in the nuclear envelope leads to bending of the structure. A quantitative distinction of the nuclear lamina shape in cell populations was found between fresh and senescent cells, and between primary myoblasts from young and old donors. Moreover, with this method mutations in lamina genes were significantly distinct from cells with wild-type genes. We suggest that this method can be applied to identify abnormal cells during aging, in in vitro propagation, and in lamina disorders. PMID:22199022

  13. Robust nuclear lamina-based cell classification of aging and senescent cells.

    PubMed

    Righolt, Christiaan H; van 't Hoff, Merel L R; Vermolen, Bart J; Young, Ian T; Raz, Vered

    2011-12-01

    Changes in the shape of the nuclear lamina are exhibited in senescent cells, as well as in cells expressing mutations in lamina genes. To identify cells with defects in the nuclear lamina we developed an imaging method that quantifies the intensity and curvature of the nuclear lamina. We show that this method accurately describes changes in the nuclear lamina. Spatial changes in nuclear lamina coincide with redistribution of lamin A proteins and local reduction in protein mobility in senescent cell. We suggest that local accumulation of lamin A in the nuclear envelope leads to bending of the structure. A quantitative distinction of the nuclear lamina shape in cell populations was found between fresh and senescent cells, and between primary myoblasts from young and old donors. Moreover, with this method mutations in lamina genes were significantly distinct from cells with wild-type genes. We suggest that this method can be applied to identify abnormal cells during aging, in in vitro propagation, and in lamina disorders.

  14. Nuclear Computerized Library for Assessing Reactor Reliability (NUCLARR)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gilbert, B.G.; Richards, R.E.; Reece, W.J.

    1992-10-01

    This Reference Guide contains instructions on how to install and use Version 3.5 of the NRC-sponsored Nuclear Computerized Library for Assessing Reactor Reliability (NUCLARR). The NUCLARR data management system is contained in compressed files on the floppy diskettes that accompany this Reference Guide. NUCLARR is comprised of hardware component failure data (HCFD) and human error probability (HEP) data, both of which are available via a user-friendly, menu driven retrieval system. The data may be saved to a file in a format compatible with IRRAS 3.0 and commercially available statistical packages, or used to formulate log-plots and reports of data retrievalmore » and aggregation findings.« less

  15. Moving Forward with Enhancements for Our Customers

    DTIC Science & Technology

    2008-11-18

    The original document contains color images. 14. ABSTRACT 15. SUBJECT TERMS 16. SECURITY CLASSIFICATION OF: 17. LIMITATION OF ABSTRACT SAR 18...Materials and Testing Alion Science & Technology CBRNIAC Chemical, Biological Radiological, Nuclear Battelle Memorial CPIAC Chemical Propulsion Johns

  16. Risk-benefit analysis of navigation techniques for vertebral transpedicular instrumentation: a prospective study.

    PubMed

    Noriega, David C; Hernández-Ramajo, Rubén; Rodríguez-Monsalve Milano, Fiona; Sanchez-Lite, Israel; Toribio, Borja; Ardura, Francisco; Torres, Ricardo; Corredera, Raul; Kruger, Antonio

    2017-01-01

    Pedicle screws in spinal surgery have allowed greater biomechanical stability and higher fusion rates. However, malposition is very common and may cause neurologic, vascular, and visceral injuries and compromise mechanical stability. The purpose of this study was to compare the malposition rate between intraoperative computed tomography (CT) scan assisted-navigation and free-hand fluoroscopy-guided techniques for placement of pedicle screw instrumentation. This is a prospective, randomized, observational study. A total of 114 patients were included: 58 in the assisted surgery group and 56 in the free-hand fluoroscopy-guided surgery group. Analysis of screw position was assessed using the Heary classification. Breach severity was defined according to the Gertzbein classification. Radiation doses were evaluated using thermoluminescent dosimeters, and estimates of effective and organ doses were made based on scan technical parameters. Consecutive patients with degenerative disease, who underwent surgical procedures using the free-hand, or intraoperative navigation technique for placement of transpedicular instrumentation, were included in the study. Forty-four out of 625 implanted screws were malpositioned: 11 (3.6%) in the navigated surgery group and 33 (10.3%) in the free-hand group (p<.001). Screw position according to the Heary scale was Grade II (4 navigated surgery, 6 fluoroscopy guided), Grade III (3 navigated surgery, 11 fluoroscopy guided), Grade IV (4 navigated surgery, 16 fluoroscopy guided), and Grade V (1 fluoroscopy guided). There was only one symptomatic case in the conventional surgery group. Breach severity was seven Grade A and four Grade B in the navigated surgery group, and eight Grade A, 24 Grade B, and one Grade C in free-hand fluoroscopy-guided surgery group. Radiation received per patient was 5.8 mSv (4.8-7.3). The median dose received in the free-hand fluoroscopy group was 1 mGy (0.8-1.1). There was no detectable radiation level in the navigation-assisted surgery group, whereas the effective dose was 10 µGy in the free-hand fluoroscopy-guided surgery group. Malposition rate, both symptomatic and asymptomatic, in spinal surgery is reduced when using CT-guided placement of transpedicular instrumentation compared with placement under fluoroscopic guidance, with radiation values within the safety limits for health. Larger studies are needed to determine risk-benefit in these patients. Copyright © 2016 Elsevier Inc. All rights reserved.

  17. Topical index and bibliography of U.S. Geological Survey Trace Elements and related reports

    USGS Publications Warehouse

    Curtis, Diane; Houser, Shirley S.

    1952-01-01

    Part 1, the topical index, lists the titles of reports prepared from 1941 to December 1952, in conjunction with the Geological Survey's program of uranium and other elements of related interest. It includes not only completed Trace Elements reports and those now in preparation, but also Survey publications, publications by Survey personnel in scientific journals, and open-fie releases. The titles are grouped topically under the headings listed in the table of contents. Entries in each category are listed alphabetically, by author, and numbered consecutively. Many of the reports have been cross-indexed, where appropriate. The classification of the Trace Elements reports, insofar as it is known, has been indicated after the title of the report. The classification of some of the earlier Trace Elements reports is uncertain. The Geological Survey does not have additional copies of most of the reports listed, but copies of some of the completed reports can be loaned on request to organizations officially cooperating with the Atomic Energy Commission. Many Trace Elements reports have been made available to the public, either by open-file release, reproduction by Technical Information Service, Oak Ridge (referred to as TIS), by publication as a Geological Survey circular or bulletin or by a publication in a scientific journal. This information is given, following the title of the report. If the abstract of a Trace Element report has been published in Nuclear Science Abstracts, it is noted by the initials NSA following the title of the report. Part 2 is a reference guide to information on the Trace Elements program that is available to the public. This information is categorized according to the type of publication or release.

  18. Molecular classifications of breast carcinoma with similar terminology and different definitions: are they the same?

    PubMed

    Tang, Ping; Wang, Jianmin; Bourne, Patria

    2008-04-01

    There are 4 major molecular classifications in the literature that divide breast carcinoma into basal and nonbasal subtypes, with basal subtypes associated with poor prognosis. Basal subtype is defined as positive for cytokeratin (CK) 5/6, CK14, and/or CK17 in CK classification; negative for ER, PR, and HER2 in triple negative (TN) classification; negative for ER and negative or positive for HER2 in ER/HER2 classification; and positive for CK5/6, CK14, CK17, and/or EGFR; and negative for ER, PR, and HER2 in CK/TN classification. These classifications use similar terminology but different definitions; it is critical to understand the precise relationship between them. We compared these 4 classifications in 195 breast carcinomas and found that (1) the rates of basal subtypes varied from 5% to 36% for ductal carcinoma in situ and 14% to 40% for invasive ductal carcinoma. (2) The rates of basal subtypes varied from 19% to 76% for HG carcinoma and 1% to 7% for NHG carcinoma. (3) The rates of basal subtypes were strongly associated with tumor grades (P < .001) in all classifications and associated with tumor types (in situ versus invasive ductal carcinomas) in TN (P < .001) and CK/TN classifications (P = .035). (4) These classifications were related but not interchangeable (kappa ranges from 0.140 to 0.658 for HG carcinoma and from 0.098 to 0.654 for NHG carcinoma). In conclusion, although these classifications all divide breast carcinoma into basal and nonbasal subtypes, they are not interchangeable. More studies are needed to evaluate to their values in predicting prognosis and guiding individualized therapy.

  19. 78 FR 30213 - 1-Naphthaleneacetic acid; Pesticide Tolerances

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-22

    ... Industrial Classification System (NAICS) codes is not intended to be exhaustive, but rather provides a guide... filing. Based upon review of the data supporting the petition, EPA has revised the proposed tolerance on... for which there is reliable information.'' This includes exposure through drinking water and in...

  20. Pesticide Application and Safety Training. Sale Publication 4070.

    ERIC Educational Resources Information Center

    Stimmann, M. W.

    This guide is intended for use by those preparing to take the California certification examination for commercial pesticide applicators. The first chapter gives brief descriptions and illustrations of types of insect, vertebrate, plant, and microorganism pests. The other chapters cover pesticide classifications and formulations, labels and…

  1. California Community Colleges Student Attendance Accounting Manual.

    ERIC Educational Resources Information Center

    Cook, Gary L.; Nussbaum, Thomas J.

    Presenting guidelines for student attendance accounting developed by the Chancellor's Office of the California Community Colleges, this manual provides an update to the original guide published in 1983. Chapter 1 explains general items such as the academic calendar, admissions policies, student classification by enrollment status, and conditions…

  2. 77 FR 50727 - Configuration Management Plans for Digital Computer Software Used in Safety Systems of Nuclear...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-22

    ... comments received on or before this date. Although a time limit is given, comments and suggestions in... guides are encouraged at any time. ADDRESSES: You may access information and comment submissions related... Research, U.S. Nuclear Regulatory Commission, Washington, DC 20555-0001; telephone: 301-251-7494 or email...

  3. Survey of Codes Employing Nuclear Damage Assessment

    DTIC Science & Technology

    1977-10-01

    surveyed codes were com- DO 73Mu 1473 ETN OF 1NOVSSSOLETE UNCLASSIFIED 1 SECURITY CLASSIFICATION OF THIS f AGE (Wh*11 Date Efntered)S<>-~C. I UNCLASSIFIED...level and above) TALLEY/TOTEM not nuclear TARTARUS too highly aggregated (battalion level and above) UNICORN highly aggregated force allocation code...vulnerability data can bq input by the user as he receives them, and there is the abil ’ity to replay any situation using hindsight. The age of target

  4. 13 CFR 121.201 - What size standards has SBA identified by North American Industry Classification System codes?

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... footnote 1 221112 Fossil Fuel Electric Power Generation See footnote 1 221113 Nuclear Electric Power... Materials and Basic Forms and Shapes Merchant Wholesalers 100 424690 Other Chemical and Allied Products...

  5. Management of Low-Flow Vascular Malformations: Clinical Presentation, Classification, Patient Selection, Imaging and Treatment

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    McCafferty, Ian, E-mail: ian.mccafferty@uhb.nhs.uk

    This review article aims to give an overview of the current state of imaging, patient selection, agents and techniques used in the management of low-flow vascular malformations. The review includes the current classifications for low-flow vascular malformations including the 2014 updates. Clinical presentation and assessment is covered with a detailed section on the common sclerosant agents used to treat low-flow vascular malformations, including dosing and common complications. Imaging is described with a guide to a simple stratification of the use of imaging for diagnosis and interventional techniques.

  6. Comprehensive Stuttering Treatment for Adolescents: A Case Study.

    PubMed

    Coleman, Craig E

    2018-01-09

    This article will focus on a hypothetical case study to highlight comprehensive assessment and treatment for adolescent children who stutter. Assessment and treatment are laid out with a literature review utilizing the components of the International Classification of Functioning, Disability and Health model. Specific assessment and treatment strategies and approaches are discussed. Using the International Classification of Functioning, Disability and Health model can help guide clinicians through the assessment and treatment process to ensure that all areas of stuttering are considered. Comprehensive assessment and treatment helps clinicians address all relevant elements of a stuttering disorder, rather than focusing exclusively on reducing speech disruptions.

  7. American Journal of Physics Resource Letters - The Future of Nuclear Power

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Parks, Cecil V; Flanagan, George F; Kulynych, George E

    2010-01-01

    This Resource Letter is intended to summarize the status of nuclear power in the world today, prospects of significant expansion of nuclear power over the next several decades, the planning of and forecasts for the addition of new power reactors, and issues surrounding the addition of these new reactors. Owing to the breadth of this subject, the list of references includes journal articles, web pages, and reports to guide the reader on the subject. The subject of nuclear power and its related issues are dynamic, so the most current information is likely to be found on reputable websites.

  8. Guide to the US collection of antarctic meteorites 1976-1988 (everything you wanted to know about the meteorite collection). Antarctic Meteorite Newsletter, Volume 13, Number 1

    NASA Technical Reports Server (NTRS)

    Score, Roberta; Lindstrom, Marilyn M.

    1990-01-01

    The state of the collection of Antarctic Meteorites is summarized. This guide is intended to assist investigators plan their meteorite research and select and request samples. Useful information is presented for all classified meteorites from 1976 to 1988 collections, as of Sept. 1989. The meteorite collection has grown over 13 years to include 4264 samples of which 2754 have been classified. Most of the unclassified meteorites are ordinary chondrites because the collections have been culled for specimens of special petrologic type. The guide consists of two large classification tables. They are preceded by a list of sample locations and important notes to make the tables understandable.

  9. Operations Praetorian, Phalanx, Fusileer, and Grenadier, Events HURON LANDING/DIAMOND ACE, MINI JADE, TOMME/MIDNIGHT ZEPHYR, MIDAS MYTH/MILAGRO and MISTY RAIN

    DTIC Science & Technology

    1993-07-01

    General requirements and standards governing safety were based on the FCTC "Safety and Health Compliance Guide for Underground and Nuclear Effects Tests...Defense (DOD)-sponsored underground nuclear tests were conducted from 23 September 1982 through 6 April 1985 to study weapons effects . All six were...weapons- related or effects purposes, and 33 were safety experiments. An additional 24 nuclear experiments were conducted from December 1954 to February

  10. 78 FR 38739 - Standard Format and Content for Post-Shutdown Decommissioning Activities Report

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-27

    ...The U.S. Nuclear Regulatory Commission (NRC) is issuing Revision 1 of Regulatory Guide (RG) 1.185, ``Standard Format and Content for Post-shutdown Decommissioning Activities Report.'' This guide describes a method that the NRC staff considers acceptable for use in complying with the Commission's requirements regarding the submission of a post-shutdown decommissioning activities report (PSDAR).

  11. 77 FR 75198 - Standard Format and Content for Post-Shutdown Decommissioning Activities Report

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-19

    ...The U.S. Nuclear Regulatory Commission (NRC) is issuing for public comment draft regulatory guide (DG), DG-1272, ``Standard Format and Content for Post-shutdown Decommissioning Activities Report.'' This guide describes a method that the NRC staff considers acceptable for use in complying with the Commission's requirements regarding the submission of a post-shutdown decommissioning activities report (PSDAR).

  12. 10 CFR Appendix C to Part 50 - A Guide for the Financial Data and Related Information Required To Establish Financial...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Required To Establish Financial Qualifications for Construction Permits and Combined Licenses C Appendix C... FACILITIES Pt. 50, App. C Appendix C to Part 50—A Guide for the Financial Data and Related Information... production plant costs $ (b) Transmission, distribution, and general plant costs $ (c) Nuclear fuel inventory...

  13. Increasing Pupil Physical Activity: A Comprehensive Professional Development Effort

    ERIC Educational Resources Information Center

    Kulinna, Pamela Hodges

    2012-01-01

    Study aim: To determine if pupil physical activity and Body Mass Index classifications maintained or improved after a one-year professional development program involving both classroom and physical education teachers. Guskey's model of teacher change guided this study. Material and methods: Indigenous children from ten schools (N = 320) in grades…

  14. A Filmography for American Indian Education.

    ERIC Educational Resources Information Center

    Williams, Carroll Warner; Bird, Gloria

    The filmography on American Indian education lists existing films in current distribution. The introduction explains the purpose of the guide, the procedure used to compile it, samples of questionnaires used, films as audiovisual classroom aids, the classification of films for classroom use, the relation of film use to individual curricula, some…

  15. 78 FR 33731 - Propamocarb; Pesticide Tolerances

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-05

    ... Modeling System (PRZM/EXAMS) and Screening Concentration in Ground Water (SCI- GROW) models, the estimated... Classification System (NAICS) codes is not intended to be exhaustive, but rather provides a guide to help readers... to the notice of filing. Based upon review of the data supporting the petition, EPA has revised the...

  16. 78 FR 24094 - Azoxystrobin; Pesticide Tolerances

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-24

    ... Classification System (NAICS) codes is not intended to be exhaustive, but rather provides a guide to help readers... response to the notice of filing. Based upon review of the data supporting the petition, EPA is... exposures for which there is reliable information.'' This includes exposure through drinking water and in...

  17. Faculty Member's Guide to U.S. Immigration Law. Revised.

    ERIC Educational Resources Information Center

    Smith, Eugene H.; Baron, Marvin J.

    Immigration laws and regulations pertaining to foreign students and scholars are summarized as an aid to faculty members. Basic immigration documents and terminology are explained, including the passport, visa, immigration status or classification, Form 1-20 ID, the "green card", and Departure Record. Classes of nonimmigrants are described,…

  18. Scenario Analysis: An Integrative Study and Guide to Implementation in the United States Air Force

    DTIC Science & Technology

    1994-09-01

    Environmental Analysis ................................ 3-3 Classifications of Environments ......................... 3-5 Characteristics of... Environments ........................ 3-8 iii Page Components of the Environmental Analysis Process ........... 3-12 Forecasting... Environmental Analysis ...................... 3-4 3-2 Model of the Industry Environment ......................... 3-6 3-3 Model of Macroenvironment

  19. A Transdiagnostic Perspective on Cognitive, Affective, and Neurobiological Processes Underlying Human Suffering

    ERIC Educational Resources Information Center

    Garland, Eric L.; Howard, Matthew O.

    2014-01-01

    The Diagnostic and Statistical Manual of Mental Disorders and International Classification of Diseases classify mental health disorders on the basis of their putatively distinct symptom profiles. Although these nosologies are highly influential, they also have been derided as mere "field guides" because they focus solely on the…

  20. ICF-CY: A Universal Tool for Documentation of Disability

    ERIC Educational Resources Information Center

    Simeonsson, Rune J.

    2009-01-01

    The "International Classification of Functioning, Disability and Health--ICF" (ICF-CY) conceptual framework offers a new paradigm and taxonomy of human functioning disability, which can be used to guide holistic and interdisciplinary approaches to assessment and intervention. In settings serving children, youth, or adults with disabilities, the…

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