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Sample records for claude amra norbert

  1. Claude Ruggieri

    NASA Technical Reports Server (NTRS)

    2004-01-01

    During the 19th century, rocket enthusiasts and inventors began to appear in almost every country. Some people thought these early rocket pioneers were geniuses, and others thought they were crazy. Claude Ruggieri, an Italian living in Paris, apparently rocketed small animals into space as early as 1806. The payloads were recovered by parachute. As depicted here by artist Larry Toschik, French authorities were not always impressed with rocket research. They halted Ruggieri's plans to launch a small boy using a rocket cluster. (Reproduced from a drawing by Larry Toschik and presented here courtesy of the artist and Motorola Inc.)

  2. Norbert Elias and the Lost Young Worker Project

    ERIC Educational Resources Information Center

    Goodwin, John; O'Connor, Henrietta

    2006-01-01

    Forty years ago, between 1962 and 1964, fieldwork was carried out on the research project "Adjustment of Young Workers to Work Situations and Adult Roles". Using archived materials relating to the little known Norbert Elias project, this paper has two aims. First, to introduce this largely unknown aspect of Elias's work to a wider…

  3. [Claude Fortier: the great history of neuroendocrinology].

    PubMed

    Rostène, William

    2005-05-01

    The work of Claude Fortier is linked to the history of neuroendocrinology. Through him and his pioneer work in Montreal with Hans Selye, the < Man of stress >, and at Laval University in Quebec City in his own laboratory, where all researchers involved in the study of the hypothalamo-hypophysial adrenal axis have been through, it is the whole saga of the search for the neuropeptide CRH (corticotropin releasing factor), and the harsh fight for the Nobel distinction that can be related. Among Claude Fortier's scientific discoveries, the feedback mechanisms of glucocorticoid hormones on brain and pituitary function, the presence of both mineralo and glucocorticoid receptors in some brain structures, and the introduction of computer science in biomedical research, can be cited. The consequences of these discoveries are illustrated in the pathologies linked to stress (anxiety, depression, addiction). Claude Fortier was not only a great figure in biomedical science, honored by several distinctions, but also an important personality in the policy of research in which he played a prominent role in Quebec medical research and allowed it to rank among the best in the world.

  4. [Claude Bernard, founder of experimental physiology].

    PubMed

    Ren, Y; Li, X; Xu, W

    2001-07-01

    Claude Bernard was a famous French physiologist and philosopher in the 19th century. His experimental researches almost involved all fields of physiology. It is generally recognized by physiologists that in the research of Bernard in the digestion of pancreas, glucogenesis in the liver, and the vasomotor mechanism and the mechanism of action of curari and carbon monoxide were all at the lead. His researches established the foundation for modern physiology, modern biochemistry and the works of Pavlov, and were the initiation of experimental physiology.

  5. Compact Claude cycle refrigerator for laboratory use

    NASA Technical Reports Server (NTRS)

    Hiersaki, Y.; Kaneko, M.; Munekata, T.; Baba, Y.; Matsubara, Y.; Yasukochi, K.

    1983-01-01

    A Claude cycle refrigerator with a three stage reciprocating expansion engine is described. Instead of a cam mechanism, valves are driven directly by magnetic solenoids operated by means of a micro processor control system. A swash plate mechanism is used to convert reciprocating motion of the expander pistons to rotary motion. A refrigeration capacity of 8 watts was achieved at 4.5 K with the operating pressure of 1.1 MPa and flow rate of 2.4 g/sec.. An effect of overintake operation was studied. Experimental results show that the efficiency of the expander has a peak point in the region of overintake operation with constant cycle speed, which agrees with theoretical results. The electrically controlled valve system is useful to vary the valve timing to achieve an optimum condition of operation.

  6. Compact Claude cycle refrigerator for laboratory use

    NASA Astrophysics Data System (ADS)

    Hiersaki, Y.; Kaneko, M.; Munekata, T.; Baba, Y.; Matsubara, Y.; Yasukochi, K.

    1983-12-01

    A Claude cycle refrigerator with a three stage reciprocating expansion engine is described. Instead of a cam mechanism, valves are driven directly by magnetic solenoids operated by means of a micro processor control system. A swash plate mechanism is used to convert reciprocating motion of the expander pistons to rotary motion. A refrigeration capacity of 8 watts was achieved at 4.5 K with the operating pressure of 1.1 MPa and flow rate of 2.4 g/sec.. An effect of overintake operation was studied. Experimental results show that the efficiency of the expander has a peak point in the region of overintake operation with constant cycle speed, which agrees with theoretical results. The electrically controlled valve system is useful to vary the valve timing to achieve an optimum condition of operation.

  7. Claude Bernard and his revelations in physiology.

    PubMed

    Breathnach, C S

    2014-03-01

    It was in Saint-Julien near Villefranche that Claude Bernard was born on 12 July 1813. About 20 years later he moved to Paris to become a dramatist but was directed into the study of medicine, the service at the Hôtel Dieu of Magendie that led him to the Collège de France. He entered Magendie's laboratory as a voluntary assistant and within a year became official préparateur. His early work on the chorda tympani and his MD thesis on gastric juice in 1843 set him on his lifelong discoveries in physiology. The central role of hepatic glycogenesis in the formation of sugar in animals was established around 1850, and he proceeded to show that section of the cervical fibres of the sympathetic chain led to congestion and increased temperature on that side of the face-resulting from paralysis of the vasomotor nerves. And there were vasodilator as well as vasoconstrictor fibres. After the salivary glands, the pancreas caught his attention and he discovered its ability to emulsify fatty material. Toxic and therapeutic substances were analysed: carbon monoxide paralyses carriage of oxygen by taking its place on haemoglobin; and curare abolishes voluntary movement by paralysis at the motor end-plate. But Bernard was above all a general physiologist, exemplified in 1872 and 1873 in his Lectures on the phenomena of life common to animals and plants, summarised in the aperçu 'the constancy of the internal environment is the condition of the free and independent life'. Claude Bernard died on Sunday 10 February 1878 in Paris.

  8. [Norbert Elias and a narrative about ageing and death].

    PubMed

    do O, Alarcon Agra

    2008-01-01

    This article investigates the contribution made by Norbert Elias (1897-1990) to the problematization of old age by analyzing his text "Envelhecer e morrer". Here, the sociologist is seen as an author of texts which can help build up references that span disciplinary boundaries, or even overcome the polarization between 'health-' and 'social-'related knowledge, making it possible to form the desired field of study on ageing. Though Elias sometimes aligns himself with ideas bordering on an idealization of ageing from a pre-capitalist 'Golden Age', he does offer insights which deserve to be taken into consideration, especially when he relates the contemporary experience of ageing to the invention of modernity itself.

  9. Claude Claremont's Contribution to the History of Science and Engineering.

    ERIC Educational Resources Information Center

    Hallenberg, Harvey R.

    1995-01-01

    Discusses the contributions of Claude Claremont to science education for children and his 1937 book, "Spanning Space," which outlines the building of models of bridges and other structures out of paper. Also describes how children and their teachers can build a model strut tower and a steam engine. (MDM)

  10. Forty Years On: Norbert Elias and the Young Worker Project. CLMS Working Paper.

    ERIC Educational Resources Information Center

    Goodwin, John; O'Connor, Henrietta

    A study performed in 1962 by Norbert Elias on the adjustment of young people to the transition from school to work had five areas of inquiry; adjustment to relationships with older workers and supervisors; adjustment to job problems; adjustment to role as workers; adjustment to role as money-earner in home relations; and adjustment to role as…

  11. A note about Norbert Wiener and his contribution to Harmonic Analysis and Tauberian Theorems

    NASA Astrophysics Data System (ADS)

    Almira, J. M.; Romero, A. E.

    2009-05-01

    In this note we explain the main motivations Norbert Wiener had for the creation of his Generalized Harmonic Analysis [13] and his Tauberian Theorems [14]. Although these papers belong to the most pure mathematical tradition, they were deeply based on some Engineering and Physics Problems and Wiener was able to use them for such diverse areas as Optics, Brownian motion, Filter Theory, Prediction Theory and Cybernetics.

  12. The aesthetics of laboratory inscription: Claude Bernard's Cahier Rouge.

    PubMed

    Sattar, Atia

    2013-03-01

    This essay explores the aesthetic sensibilities of the French physiologist Claude Bernard (1813-1878). In particular, it analyzes the Cahier Rouge (1850-1860), Bernard's acclaimed laboratory notebook. In this notebook, Bernard articulates the range of his experience as an experimental physiologist, juxtaposing without differentiation details of laboratory procedure and more personal queries, doubts, and reflections on experimentation, life, and art. Bernard's insights, it is argued, offer an aesthetic and phenomenological template for considering experimentation. His physiological point of view ranges from his own bodily aesthesis or sensory perception, through personal reflections on scientific discovery as an artistic process, to a broader metaphysical conception of life as an artistic creation. Such an aesthetic approach to physiology enables Bernard to reconcile his empirical methodology and his romantic idealism; it offers the history of laboratory science a framework for considering the individual, bodily, and emotional labor inherent in physiological experimentation.

  13. Claude Lévi-Strauss on Race, History, and Genetics

    PubMed Central

    Müller-Wille, Staffan

    2015-01-01

    In 1952, the French anthropologist Claude Lévi-Strauss published a small booklet titled Race and History. It formed part of a series of pamphlets on the so-called “race-question” by leading anthropologists and geneticists, which UNESCO published as part of its campaign against racism. Roughly twenty years later, in 1971, UNESCO invited Lévi-Strauss to give a lecture to open the International Year of Action to Combat Racism and Racial Discrimination. This time the lecture, titled “Race and culture,” caused a scandal. In 2005, on occasion of the Organisation’s 60th anniversary, Lévi-Strauss was once again invited by UNESCO to give a lecture. It followed the same lines as his 1971 speech, but now met with acclaim. In my paper I will analyze Lévi-Strauss’ interventions with respect to their reliance on contemporary genetics. Lévi-Strauss always saw a close analogy between structuralist anthropology and genetics, and derived his anti-evolutionary stance from the combinatory logic that both disciplines endorsed. I will argue, that it was this combinatory logic which created room for historical contingency and agency in Lévi-Strauss’ understanding of the history of humankind. PMID:25685173

  14. [Claude Perrault, famous architect, unknown physician, untiring researcher].

    PubMed

    Hazard, Jean

    2007-01-01

    As a famous architect Charles Perrault persuaded Colbert to appoint a committee of the "Bâtiments du Roi" made up of three persons: Le Vau, Le Brun and one of his brothers Claude whose Louis XIV chose the plan. While Le Vau was busy in Versailles Perrault's influence became dominating. Although he was an unknown medical practitioner he managed to be allowed to practise and to teach medicine and to be a member of theses' jury for twenty five years. He was highly regarded by his colleagues who did not hesitate to hold a consultation. His trip in Bordeaux was consecrated to look after his brother but because of his numerous occupations he gave up practising medicine and he only treated the members of his family, his friends and some poor. He was a tireless researcher and at the "Académie des Sciences" he looked after the "Histoire naturelle des animaux" (Natural History of the Animals). In "Les Essais de Physique" he tackled numerous problems of physiology such as elasticity and contractility of arteries, studied the sense organs and did some experiments about blood transfusion. As an exceptional man he could practise the three of the occupations.

  15. Reconsidering Feminisms and the Work of Norbert Elias for Understanding Gender, Sport and Sport-Related Activities

    ERIC Educational Resources Information Center

    Mansfield, Louise

    2008-01-01

    This paper reconsiders the relationships between feminist perspectives and the figurational/process-sociological perspective of Norbert Elias for understanding gender, sport and sport-related activities. The main aim of the article is to respond to Colwell's claim that there are differences between feminist and figurational approaches to…

  16. Children's Invented Notations and Verbal Responses to a Piano Work by Claude Debussy

    ERIC Educational Resources Information Center

    Elkoshi, Rivka

    2015-01-01

    This study considers the way children listen to classical music composed for them and the effect of age on their spontaneous invented notations and verbal responses. The musical selection is a piano piece for children by Claude Debussy:"'Jimbo's Lullaby" from "Children's Corner". Two hundred and nine children 4-9.5-years-old…

  17. [The driving force in the thinking of Norbert Elias. An attempt at psychoanalytic interpretation].

    PubMed

    Schröter, M

    1993-07-01

    The theory of civilization proposed by the eminent sociologist Norbert Elias, who died in 1990, has its roots in Freud's theory of culture. Elias always denied the importance of personal factors in connection with his work, but as has been demonstrated in connection with artists such as Leonardo da Vinci and indeed Freud himself, this does not make it any the less legitimate to go in search of those infantile/unconscious motifs and affective sources powering Elias' prodigious scholarly creativity and informing his work, in however sublimated a form. Proceeding from the observation that successful scholarly or artistic production represents a synthesis of the forces of id, ego and super-ego, i.e. of affect, knowledge and conscience, the author demonstrates that concerns of central moment to Elias' thinking--commitment and non-involvement, establishment and outsider, the restraining of aggression in the civilizational process, interdependence of individuals--are partly the product of early experiences which Elias was able to turn to fruitful account in his work.

  18. Norbert Elias's motion pictures: history, cinema and gestures in the process of civilization.

    PubMed

    Algazi, Gadi

    2008-09-01

    Norbert Elias's project in The process of civilization (1939) involved reconstructing invisible movement--both the slow tempoof long-term historical change and the modification of psychic structures and embodied dispositions. To do this, he resorted to uncommon devices: treating historical texts as constituting a series amenable to a rudimentary discourse analysis, he constructed an imagined 'curve of civilization' serving as an approximation of the hidden process of change. Elias's curve was not supposed to represent single past states, but movement itself, its direction and pace. This novel concept of historical representation was related to the perception of cinema as a new medium making actual movement visible. But beyond making it possible to imagine how one could telescope long-term historical process, cinema also held the promise of serving as a microscope, making the minute movements of the human body, gestures and manners available for close inspection. While anthropologists were devising ways of using the new medium to document fleeting gestures and bodily postures, it was used by popular audiences as a source for remodelling behaviour and acquiring polite manners and body techniques, as noticed by such acute observers as Marcel Mauss and Joseph Roth. Hence, popular appropriation of the cinema gave rise to a heightened awareness of the historicity of gestures and the changing modalities of their transmission. Cinema was itself part of the accelerated motion of history, of a perceived change of pace in the process of civilization, which in its turn shed light on its historical antecedents and played an essential role in rethinking the notion of civilization and culture.

  19. Claude Bernard, the first systems biologist, and the future of physiology.

    PubMed

    Noble, Denis

    2008-01-01

    The first systems analysis of the functioning of an organism was Claude Bernard's concept of the constancy of the internal environment (le milieu intérieur), since it implied the existence of control processes to achieve this. He can be regarded, therefore, as the first systems biologist. The new vogue for systems biology today is an important development, since it is time to complement reductionist molecular biology by integrative approaches. Claude Bernard foresaw that this would require the application of mathematics to biology. This aspect of Claude Bernard's work has been neglected by physiologists, which is why we are not as ready to contribute to the development of systems biology as we should be. In this paper, I outline some general principles that could form the basis of systems biology as a truly multilevel approach from a physiologist's standpoint. We need the insights obtained from higher-level analysis in order to succeed even at the lower levels. The reason is that higher levels in biological systems impose boundary conditions on the lower levels. Without understanding those conditions and their effects, we will be seriously restricted in understanding the logic of living systems. The principles outlined are illustrated with examples from various aspects of physiology and biochemistry. Applying and developing these principles should form a major part of the future of physiology.

  20. Plant anesthesia supports similarities between animals and plants: Claude Bernard's forgotten studies.

    PubMed

    Grémiaux, Alexandre; Yokawa, Ken; Mancuso, Stefano; Baluška, František

    2014-01-01

    The French scientist Claude Bernard (1813-1878) is famous for his discoveries in physiology and for introducing rigorous experimental methods to medicine and biology. One of his major technical innovations was the use of chemicals in order to disrupt normal physiological function to test hypotheses. But less known is his conviction that the physiological functions of all living organisms rely on the same underlying principles. He hypothesized that similarly to animals, plants are also able to sense changes in their environment. He called this ability "sensitivity." In order to test his ideas, he performed anesthesia on plants and the results of these experiments were presented in 1878 in "Leçonssur les phénomènes de la vie communs aux animaux et aux végétaux." The phenomena described by Claude Bernard more than a century ago are not fully understood yet. Here, we present a short overview of anesthetic effects in animals and we discuss how anesthesia affects plant movements, seed germination, and photosynthesis. Surprisingly, these phenomena may have ecological relevance, since stressed plants generate anesthetics such as ethylene and ether. Finally, we discuss Claude Bernard's interpretations and conclusions in the perspective of modern plant sciences.

  1. Norbert Elias, maritime supremacy and the naval profession: on Elias' unpublished studies in the genesis of the naval profession.

    PubMed

    Moelker, René

    2003-09-01

    In 1950 Norbert Elias published the first of three studies on 'The Genesis of the Naval Profession' in the British Journal of Sociology. At the time Elias was not the established scholar that he was to become in later days. In the 1950s his work on the 'Naval Profession' was not well received by the audience, even though all the major themes of the 'civilizing process' were interwoven in the article. The other two studies were never published in English journals (only one was published in a Dutch journal but received no international attention). A perusal of the Norbert Elias Archive in Marbach am Neckar in Germany--shows that the 'Naval Profession' project is larger than the intended three part series of articles for the BJS. From an outline to the project found in the archive it can be concluded that Elias intended to write a book with six to seven chapters. The key to the studies is a sketchy theory of institutions, which states that conflict promotes institutional development. Through the conflict between two occupational groups, sailors and soldiers, the naval officer becomes institutionalized as a new profession. During the period this process takes place England acquires maritime supremacy, secures the passages to the colonies and becomes an empire.

  2. Composite turbine blade design options for Claude (open) cycle OTEC power systems

    SciTech Connect

    Penney, T R

    1985-11-01

    Small-scale turbine rotors made from composites offer several technical advantages for a Claude (open) cycle ocean thermal energy conversion (OTEC) power system. Westinghouse Electric Corporation has designed a composite turbine rotor/disk using state-of-the-art analysis methods for large-scale (100-MW/sub e/) open cycle OTEC applications. Near-term demonstrations using conventional low-pressure turbine blade shapes with composite material would achieve feasibility and modern credibility of the open cycle OTEC power system. Application of composite blades for low-pressure turbo-machinery potentially improves the reliability of conventional metal blades affected by stress corrosion.

  3. [Claude Bernard-Horner's syndrome due to malignant pleural mesothelioma (author's transl)].

    PubMed

    Baris, Y I

    1980-01-01

    Seven cases of Claude Bernard-Horner's syndrome due to malignant pleural mesothelioma are described. All the patients were middle aged farmers and lived in the rural part of Central Anatolia. Two of them lived in Karain and had been exposed to inhale erionite type zeolite fibres. Hence the other five subjects lived in asbestos deposit areas. Pleural effusion, pleural thickening and nodular pleural lesions were the radiological findings. Rib erosion was found in one case. All the patients had tissue diagnosis by pleural punch biopsy, thoracoscopy or thoracotomy.

  4. From bench to bedside: Claude Bernard, Henry K. Beecher, MD, and science in anesthesia.

    PubMed

    Edwards, Matthew L

    2013-04-01

    Success with the medical management of pain grew tremendously after William Thomas Green Morton's successful demonstration of surgical anesthesia in 1846: Henry K. Beecher's clinical and experimental contributions to anesthesia during and after World War II had a profound impact on how clinicians and experimentalists study human populations in medicine. Beecher found that pain research required human subjects because pain was different for each individual. Nearly 100 years before Beecher, Claude Bernard similarly considered the complexity and uniqueness of human research subjects. Bernard and Beecher both preferred animal subjects in research when appropriate, but suggested that studies involving some mental, bodily, and cognitive processes required human subjects. Although Beecher and Bernard's lives did not overlap, these two men similarly confronted the issues of complexity in human and animal research, particularly in those phenomena involving higher cognitive functions.

  5. Ilya Neustadt, Norbert Elias, and the Leicester Department: personal correspondence and the history of sociology in Britain.

    PubMed

    Goodwin, John; Hughes, Jason

    2011-12-01

    The central aims of this paper are: (1) to explore the utility of using personal correspondence as a source of data for sociological investigations into the history of sociology in the UK; (2) in relation to this undertaking, to advance the beginnings of a figurational analysis of epistolary forms; and (3), to provide an empirically-grounded discussion of the historical significance of the Department of Sociology at the University of Leicester (a University largely ignored in 'standard histories' of the subject) at a formative phase in the development of the discipline within the UK. The correspondence drawn upon in the paper is between Norbert Elias and Ilya Neustadt between 1962 and 1964 when Elias was Professor of Sociology at the University of Ghana and Ilya Neustadt was Professor of Sociology and Head of the Sociology Department at the University of Leicester. From an analysis of this correspondence, we elucidate an emergent dynamic to the relationship between Neustadt and Elias, one which, we argue, undergirds the development of sociology at Leicester and the distinctive character of the intellectual climate that prevailed there during the 1960s. The paper concludes with a consideration of whether it was a collapse of this dynamic that led to a total breakdown in the relationship between Neustadt and Elias, and by extension, an important phase in the expansion of sociology at Leicester.

  6. Claude Bernard and an introduction to the study of experimental medicine: "physical vitalism," dialectic, and epistemology.

    PubMed

    Normandin, Sebastian

    2007-10-01

    This article explores the profound impact of the thought of Claude Bernard (1813-78) and his philosophy of experimentalism elaborated in his masterwork An Introduction to the Study of Experimental Medicine. I argue that Bernard's far-ranging theoretical impact on medicine and biology marks the end of conventional vitalism and the elusive notion of a "vital force" as a legitimate scientific concept. His understanding of medicine is as epistemologically significant in its time as Newton's contribution was to the physical sciences in the seventeenth century. This essay treats Bernard's philosophical ambitions seriously, exploring his important, even central, role in the mental world of nineteenth-century France. This includes his influence on Henri Bergson (1859-1941) and other late-nineteenth century thinkers. The subtext of Bernard's experimental epistemology is also contrasted with a key idealist philosopher of the period, the German Arthur Schopenhauer (1788-1860), and placed in the context of the larger European philosophical sphere. In contrast to much of mid-nineteenth-century philosophy, Bernard, in creating the framework for experimental medicine, argued for an experimental approach in which a priori assumptions were to be strictly constrained. Bernard's thoughts on the nature of experiment put an end to "systems" in medicine, ironically by replacing all previous medical philosophies with the all-embracing "system" of experiment. And yet, while "vital forces" fade after Bernard, a form of vitalism still flourishes. Even in Bernard's own work, in the struggle with concepts like determinism, complexity, and causality, there is a realization of the unique character of living function in a kind of "physical vitalism."

  7. The Scriptural Cantatas "Esther" and "Jacob, et Rachel" of Elisabeth-Claude Jacquet de La Guerre: Historical Context and Performance Practice

    ERIC Educational Resources Information Center

    Buckley, Elizabeth M.

    2009-01-01

    This project explores two sacred cantatas of Elisabeth-Claude Jacquet de La Guerre, "Esther" and "Jacob, et Rachel". The cultural milieu in which the sacred cantatas of Jacquet de La Guerre were written and performed will be discussed, as well as possible venues for their original performances, including the Parisian salon, and…

  8. [The chief surgeon Claude Louis Sommé (1772-1855) French military physician, surgeon of Antwerp hospital].

    PubMed

    Tricot, Jean-pierre

    2015-01-01

    Claude Louis Sommé was born in Paris in 1772. After surgical studies between 1790 and 1792, he successfully embraced a military career in the armies of Napoleon at different fronts and in several hospitals. In 1806 he submitted his doctoral thesis at the Special Medical School of Strasburg, Dissertation upon Pain. The same year he presented his dismissal from he imperial armies and became chief-surgeon at the St Elisabeth hospital of Antwerp where he stayed on duty until his death in 1855. Sommé wrote a lot of medical books: surgical, anatomical and physiological. After the battle of Waterloo one third of the injured soldiers were transferred to Antwerp and were attended in his department. He also played an important role as a professor at the Primary Medical School of Antwerp. Sommé also created the botanical garden of Antwerp, close to the hospital.

  9. Numerical studies on sizing/ rating of plate fin heat exchangers for a modified Claude cycle based helium liquefier/ refrigerator

    NASA Astrophysics Data System (ADS)

    Goyal, M.; Chakravarty, A.; Atrey, M. D.

    2017-02-01

    Performance of modern helium refrigeration/ liquefaction systems depends significantly on the effectiveness of heat exchangers. Generally, compact plate fin heat exchangers (PFHE) having very high effectiveness (>0.95) are used in such systems. Apart from basic fluid film resistances, various secondary parameters influence the sizing/ rating of these heat exchangers. In the present paper, sizing calculations are performed, using in-house developed numerical models/ codes, for a set of high effectiveness PFHE for a modified Claude cycle based helium liquefier/ refrigerator operating in the refrigeration mode without liquid nitrogen (LN2) pre-cooling. The combined effects of secondary parameters like axial heat conduction through the heat exchanger metal matrix, parasitic heat in-leak from surroundings and variation in the fluid/ metal properties are taken care of in the sizing calculation. Numerical studies are carried out to predict the off-design performance of the PFHEs in the refrigeration mode with LN2 pre-cooling. Iterative process cycle calculations are also carried out to obtain the inlet/ exit state points of the heat exchangers.

  10. [A brief history of the baroreceptor reflex: from Claude Bernard to Arthur C. Guyton. Illustrated with some classical experiments].

    PubMed

    Estañol, Bruno; Porras-Betancourt, Manuel; Padilla-Leyva, Miguel Ángel; Sentíes-Madrid, Horacio

    2011-01-01

    The baroreceptor reflex is poorly known by most physicians even though is fundamental in stabilizing the blood pressure on a beat to beat basis and is crucial for survival. Its fascinating history is briefly reviewed in this article. In 1852 Claude Bernard discovered that the sympathetic nerves of the neck innervate the blood vessels of the skin of the rabbit. Edgar Douglas Adrian in 1932 demonstrated that the sympathetic nerves that innervate the blood vessels discharge spontaneously at a rate of 4-6 per second and thus discovered the physiological basis of the vasomotor tone. In the XIX century Ludwig Traube and Karl Constantine Ewald Hering discovered that blood pressure fluctuates synchronously with respiratory movements and Sigmund Mayer observed that there are also slow non respiratory fluctuations of blood pressure. In 1921 Heinrich Ewald Hering found that high pressure baroreceptors are located in the carotid sinuses and demonstrated that the stimulation of the afferent nerve that innervates it induces bradycardia and hypotension. These studies were further advanced by Corneille Heymans who won the Nobel Prize for these studies in 1938. Later Cowley and Guyton produced sino-aortic denervation in dogs and thereby could demonstrate the fundamental importance of the baroreceptor reflex in the stabilization of blood pressure.

  11. [Social institutions and tempering of affects as "contraints" of social change. Norbert Elias' theory on the civilization theory in light of the biologic system theory of evolution].

    PubMed

    Weinich, Detlef

    2005-01-01

    This study is to be regarded as a contribution to interdisciplinary research and represents an attempt to clarify the question of whether and to what extent concepts that have been developed in the field of theoretical biology and which have a high degree of importance here can also be applied to sociological phenomena. In particular it is intended to examine the question of whether the civilizing process can be adequately treated using the evolutionary concept of "Constraints". This term, which has only recently been introduced into the discussion by PERE ALBERCH as an evolutionary factor, comprises all of the internal factors which influence the further course of the evolution of a system by ruling out certain possibilities, thus showing a limiting effect. Although "Constraints" go beyond the scope of Darwinian teachings about selection by the environment, they are increasingly accepted today as evolution factors by well-known exponents of Darwinian theory (cf. MAYNARD-SMITH 1985). The increase in popularity of "constraints" is also an expression of the rediscovery of a phenomenon which was originally expressed by RUPERT RIEDL and was introduced by him into German literature in the seventies. In the clarification of this question, special reference is made to the "theory of the civilizing process" by NORBERT ELIAS, since here a highly respected scholar has presented an important sociological theory. Moreover, there is such good scientific access to ELIAS because this author exemplifies his theses in historical terms and thus to a certain extent makes his explanations verifiable in scientific terms. In the treatment of this topic, the central terms and theses of ELIAS will be presented from the considerable scope of his work, and then illustrated with the help of several selected historical case studies. Furthermore, reference will be made at the relevant points to parallels and analogies which the works of ELIAS have to other, predominantly system

  12. [Comment on “Plate tectonics: Scientific revolution or scientific program?” by Jean-Claude Mareschal] Development of plate tectonics theory: The missing piece

    NASA Astrophysics Data System (ADS)

    Doe, Bruce R.

    The recent article by Jean-Claude Mareschal (“Plate Tectonics: Scientific Revolution or Scientific Program?” in Eos, May 19, 1987, p. 529) adds to the interesting literature on the evolution of the theory of plate tectonics. It is curious that an aspect of the general theory that seems to be little considered and mentioned by Mareschal or others who write about the history of development of the theory, but that was vitally important in my own acceptance of the theory, was the discovery of subduction and, to a lesser extent, abduction.

  13. [Claude Bernard and the Comptes Rendus de la Société de Biologie: the movie of the physiological revolution by him who made it (1849-1878)].

    PubMed

    Hainaut, Jean

    2009-01-01

    Claude Bernard presented most of his fundamental results to the Société de Biologie, including proof of the modulation of the nervous system by the internal micromilieu. However, he did not describe the principle of a stable internal milieu as a condition for free life. Physiology, which is a part of biology, was not founded on cellular biology. Rather, Claude Bernard considered chemistry, anatomy and histology as the necessary auxiliary sciences for physiology. His articles are direct pictures, and not isolated ones, despite possible limitations, from a pre-montage movie of the physiological revolution he thought he had initiated, but not finished.

  14. Claude Bernard Distinguished Lecture. Becoming a truly helpful teacher: considerably more challenging, and potentially more fun, than merely doing business as usual.

    PubMed

    Jason, Hilliard

    2007-12-01

    Few medical faculty members are adequately prepared for their instructional responsibilities. Our educational traditions were established before we had research-based understandings of the teaching-learning process and before brain research began informing our understandings of how humans achieve lasting learning. Yet, there are several advantages you may have. If your expertise is at one of the frontiers of human biology, your teaching can be inherently fascinating to aspiring health professionals. If your work has implications for human health, you have another potential basis for engaging future clinicians. And, thanks to Claude Bernard's influence, you likely are "process oriented," a necessary mindset for being an effective teacher. There are also challenges you may face. Your medical students will mostly become clinicians. Unless you can help them see connections between your offerings and their future work, you may not capture and sustain their interest. To be effective, teachers, like clinicians, need to be interactive, make on-the-spot decisions, and be "emotional literate." If you aren't comfortable with these demands, you may have work to do toward becoming a truly helpful teacher. Program changes may be needed. Might your program need to change 1) from being adversarial and controlling to being supportive and trust based or 2) from mainly dispensing information to mainly asking and inviting questions? In conclusion, making changes toward becoming a truly helpful teacher can bring benefits to your students while increasing your sense of satisfaction and fulfillment as a teacher. If you choose to change, be gentle with yourself, as you should be when expecting your students to make important changes.

  15. Norbert Elias and the civilized prison.

    PubMed

    Pratt, J

    1999-06-01

    This paper employs an Eliasian perspective to provide an historical overview to the contemporary crisis in British prisons. It argues that some of the roots of this crisis lie within the very attempts to bring prison development in line with the cultural values of modern society.

  16. The Sonnet Tradition and Claude McKay

    ERIC Educational Resources Information Center

    Denize, Donna E. M.; Newlin, Louisa

    2009-01-01

    This year marks the 400th anniversary of the publication of the first edition of Shakespeare's 154 sonnets--an excellent moment to focus on them, as well as on those written by others before and after 1609. Because these authors share an enthusiasm for poetry in general and the sonnet in particular, they want to encourage teachers to include…

  17. From Claude Bernard to the Batcave and Beyond: Using Batman as a Hook for Physiology Education

    ERIC Educational Resources Information Center

    Zehr, E. Paul

    2011-01-01

    Communicating physiology to the general public and popularizing science can be tremendously rewarding activities. Providing relevant and compelling points of linkage, however, between the scientific experiences and the interests of the general public can be challenging. One avenue for popularizing science is to link scientific concepts to images,…

  18. The 2014 Claude Bernard Distinguished Lecture: The Social Contract of Learning

    ERIC Educational Resources Information Center

    Carroll, Robert G.

    2015-01-01

    The shift to competency-based education expands the role of the teacher from that of a provider of information and into a shaper of knowledge, skills, and attitudes. These roles are facilitated by establishing a social contract between the instructor and learner, a contract that clearly defines the rights and duties of each. Adopting greater…

  19. The 2014 Claude Bernard Distinguished Lecture: the social contract of learning.

    PubMed

    Carroll, Robert G

    2015-03-01

    The shift to competency-based education expands the role of the teacher from that of a provider of information and into a shaper of knowledge, skills, and attitudes. These roles are facilitated by establishing a social contract between the instructor and learner, a contract that clearly defines the rights and duties of each. Adopting greater responsibility for the development of competencies in our learners allows faculty members to truly have an impact by shaping the behaviors of learners.

  20. Alpha List of Prime Contract Awards. Oct 92-Sep 93. FY93. (Claude Ralph - Day Francis O Co. Inc.)

    DTIC Science & Technology

    1994-03-01

    NN (r- (Y) cl 4 (In w P1 < IfIL)f in0. II4 V 010cv 04dcC 04 0010101 000 000 04< 04 0(01 001D x if 010.-V 1 LLa. . 0 0 xZZ U.L- ZZ 0 0 z Z: CIL1 I 1 0...IUI 64 lOO0N 11W 6-Z1 1, UON O O40. l𔃺 WOO j M00 00 I.- ZH 4J I caO0N i i P1 . 9 WJ 0 W cr Z .OOOOOOOOO >O Z00 0 00 4 0i 0 11cIIClOON 11W U 0 ’ ~0U0...to10 1 00 -4(’ CV 11 4) (𔃻 U4 N L M 010010 101010 f ( u)LnL II I1~ N M-cy It IN ON N) 01010 P.M. 4fý(.r ýrý() WW S11-N11 1 0 10 p1 (4 10i CO 10C

  1. Obesity and Gestational Diabetes Mellitus Pathways for Programming in Mouse, Monkey, and Man—Where Do We Go Next? The 2014 Norbert Freinkel Award Lecture

    PubMed Central

    2015-01-01

    Obesity and gestational diabetes mellitus continue to increase worldwide and span the spectrum of age, race, ethnicity, and socioeconomic status. Alarmingly, 1 in 10 infants and toddlers is obese, and 1 in 5 youths is both obese and at risk for metabolic syndrome prior to puberty. The mechanisms underlying how poor maternal health imparts risk for future metabolic disease in the offspring are beginning to emerge in deeply phenotyped human and nonhuman primate models. Maternal diet and obesity impact fuels, hormones, and inflammation with powerful effects on fetal metabolic systems. These are accompanied by persistent changes in the infant microbiome and epigenome and in offspring behavior. These results suggest that gestational and lactational dietary exposures are driving health risks in the next generation. Whether maternal diet can prevent changes in the womb to alter infant life-course disease risk is still unknown. Controlled, mechanistic studies to identify interventions are sorely needed for a healthier next generation. PMID:26207051

  2. Obesity and Gestational Diabetes Mellitus Pathways for Programming in Mouse, Monkey, and Man—Where Do We Go Next? The 2014 Norbert Freinkel Award Lecture.

    PubMed

    Friedman, Jacob E

    2015-08-01

    Obesity and gestational diabetes mellitus continue to increase worldwide and span the spectrum of age, race, ethnicity, and socioeconomic status. Alarmingly, 1 in 10 infants and toddlers is obese, and 1 in 5 youths is both obese and at risk for metabolic syndrome prior to puberty. The mechanisms underlying how poor maternal health imparts risk for future metabolic disease in the offspring are beginning to emerge in deeply phenotyped human and nonhuman primate models. Maternal diet and obesity impact fuels, hormones, and inflammation with powerful effects on fetal metabolic systems. These are accompanied by persistent changes in the infant microbiome and epigenome and in offspring behavior. These results suggest that gestational and lactational dietary exposures are driving health risks in the next generation. Whether maternal diet can prevent changes in the womb to alter infant life-course disease risk is still unknown. Controlled, mechanistic studies to identify interventions are sorely needed for a healthier next generation.

  3. Philosophical basis and some historical aspects of systems biology: from Hegel to Noble - applications for bioenergetic research.

    PubMed

    Saks, Valdur; Monge, Claire; Guzun, Rita

    2009-03-01

    We live in times of paradigmatic changes for the biological sciences. Reductionism, that for the last six decades has been the philosophical basis of biochemistry and molecular biology, is being displaced by Systems Biology, which favors the study of integrated systems. Historically, Systems Biology - defined as the higher level analysis of complex biological systems - was pioneered by Claude Bernard in physiology, Norbert Wiener with the development of cybernetics, and Erwin Schrödinger in his thermodynamic approach to the living. Systems Biology applies methods inspired by cybernetics, network analysis, and non-equilibrium dynamics of open systems. These developments follow very precisely the dialectical principles of development from thesis to antithesis to synthesis discovered by Hegel. Systems Biology opens new perspectives for studies of the integrated processes of energy metabolism in different cells. These integrated systems acquire new, system-level properties due to interaction of cellular components, such as metabolic compartmentation, channeling and functional coupling mechanisms, which are central for regulation of the energy fluxes. State of the art of these studies in the new area of Molecular System Bioenergetics is analyzed.

  4. DoD Prime Contract Awards over $25,000 by Contractor, State and City. FY 1993. (Oct-Feb). Claude Ralph-Hussman Corporation. Part 2

    DTIC Science & Technology

    1994-03-01

    m to -.4 L- C O 4 00Ac o 604 to0 00 .cI~ to6 c)In E0( 01-.( 00 >In -C go 0 N1I-C q00t C 0 -01%- NN -4.4 In%4 00 tauC ’ c-00 to Nn -- #a-" -M 600 E- W...l ol( ..40 ,,a. 4 22= .- 4 -4 0 4z W1 00 4) 04 -Nf(-4 C02-4I~( 1- u .4 N D-(OD=c -4 0 fm o o 1 > -4 mm .- C.4 0 o- L- V C3 ’.4 -- 1mc 40ca (0 - loi IL

  5. Perception of the A/H1N1 influenza pandemic and acceptance of influenza vaccination by Université Claude Bernard Lyon 1 staff: A descriptive study.

    PubMed

    Amour, Sélilah; Djhehiche, Khaled; Zamora, Adeline; Bergeret, Alain; Vanhems, Philippe

    2015-01-01

    We assessed the perception and attitudes of university staff, including medical school and other science specialties, toward the 2009 A/H1N1 influenza pandemic and influenza vaccination program. A cross-sectional online survey was conducted among 4,529 university personnel on October 19-20, 2009. Seven hundred (15%) employees participated in the study. Only 18% were willing to be vaccinated, men more than women (29% versus 9%, P < 0.001), and professors/researchers more than administrative/technical staff (30% vs. 6%, P < 0.001). Intention to be vaccinated was insufficient. Additional efforts are needed to improve information dissemination among university staff. Medical university personnel should receive more information to increase vaccine coverage and protect them as well as patients.

  6. Perception of the A/H1N1 influenza pandemic and acceptance of influenza vaccination by Université Claude Bernard Lyon 1 staff: A descriptive study

    PubMed Central

    Amour, Sélilah; Djhehiche, Khaled; Zamora, Adeline; Bergeret, Alain; Vanhems, Philippe

    2015-01-01

    We assessed the perception and attitudes of university staff, including medical school and other science specialties, toward the 2009 A/H1N1 influenza pandemic and influenza vaccination program. A cross-sectional online survey was conducted among 4,529 university personnel on October 19–20, 2009. Seven hundred (15%) employees participated in the study. Only 18% were willing to be vaccinated, men more than women (29% versus 9%, P < 0.001), and professors/researchers more than administrative/technical staff (30% vs. 6%, P < 0.001). Intention to be vaccinated was insufficient. Additional efforts are needed to improve information dissemination among university staff. Medical university personnel should receive more information to increase vaccine coverage and protect them as well as patients. PMID:25715115

  7. Beyond Compassion: Children of Sex Workers in Kolkata's Sonagachi

    ERIC Educational Resources Information Center

    Sircar, Oishik; Dutta, Debolina

    2011-01-01

    In 2005, children of sex workers from Kolkata's Sonagachi red-light district formed their own collective, Amra Padatik ("We are Foot Soldiers"), to work for gaining dignity for their mothers and claiming their own rights as children of sex workers. In this article the authors speak to AP's founder members to demystify the culture of fear…

  8. Validation of a fast method for quantification of intra-abdominal and subcutaneous adipose tissue for large-scale human studies.

    PubMed

    Borga, Magnus; Thomas, E Louise; Romu, Thobias; Rosander, Johannes; Fitzpatrick, Julie; Dahlqvist Leinhard, Olof; Bell, Jimmy D

    2015-12-01

    Central obesity is the hallmark of a number of non-inheritable disorders. The advent of imaging techniques such as MRI has allowed for a fast and accurate assessment of body fat content and distribution. However, image analysis continues to be one of the major obstacles to the use of MRI in large-scale studies. In this study we assess the validity of the recently proposed fat-muscle quantitation system (AMRA(TM) Profiler) for the quantification of intra-abdominal adipose tissue (IAAT) and abdominal subcutaneous adipose tissue (ASAT) from abdominal MR images. Abdominal MR images were acquired from 23 volunteers with a broad range of BMIs and analysed using sliceOmatic, the current gold-standard, and the AMRA(TM) Profiler based on a non-rigid image registration of a library of segmented atlases. The results show that there was a highly significant correlation between the fat volumes generated by the two analysis methods, (Pearson correlation r = 0.97, p < 0.001), with the AMRA(TM) Profiler analysis being significantly faster (~3 min) than the conventional sliceOmatic approach (~40 min). There was also excellent agreement between the methods for the quantification of IAAT (AMRA 4.73 ± 1.99 versus sliceOmatic 4.73 ± 1.75 l, p = 0.97). For the AMRA(TM) Profiler analysis, the intra-observer coefficient of variation was 1.6% for IAAT and 1.1% for ASAT, the inter-observer coefficient of variation was 1.4% for IAAT and 1.2% for ASAT, the intra-observer correlation was 0.998 for IAAT and 0.999 for ASAT, and the inter-observer correlation was 0.999 for both IAAT and ASAT. These results indicate that precise and accurate measures of body fat content and distribution can be obtained in a fast and reliable form by the AMRA(TM) Profiler, opening up the possibility of large-scale human phenotypic studies.

  9. "Requestioning" AIDS: An Ethical Reflection From 1993 to Today. Reflections on Claude Vandevyer's "Homosexuals and AIDS: A New Approach to the Illness" from Journal of Homosexuality 25(3).

    PubMed

    Lau, Travis

    2016-01-01

    This article serves as one of the supplementary pieces of this special issue on "Mapping Queer Bioethics," in which we take a solipsistic turn to "map" the Journal of Homosexuality itself. Here, the author examines the first feature-length article to address the relationship between HIV status and homosexuality. Lingering on both the temporal gap between the dawn of AIDS in American discourse and its inclusion in this journal, the author asks us to consider (in hindsight) such a delay bearing in mind queer theoretical projects of the present such as gay shame, stigma, and queer biopolitics.

  10. Teaching and Learning in the Interactive Classroom

    ERIC Educational Resources Information Center

    Silverthorn, D. U.

    2006-01-01

    The Claude Bernard Distinguished Lectureship of the Teaching of Physiology Section is presented annually at the Experimental Biology meeting. The lectureship is named for Prof. Claude Bernard, the experimental physiologist who is credited with introducing the concept of homeostasis. The 2006 Claude Bernard Distinguished Lecture was given by Dr.…

  11. Teaching and learning in the interactive classroom.

    PubMed

    Silverthorn, D U

    2006-12-01

    The Claude Bernard Distinguished Lectureship of the Teaching of Physiology Section is presented annually at the Experimental Biology meeting. The lectureship is named for Prof. Claude Bernard, the experimental physiologist who is credited with introducing the concept of homeostasis. The 2006 Claude Bernard Distinguished Lecture was given by Dr. Dee U. Silverthorn from the University of Texas at Austin, TX.

  12. Learning to Mock--Challenging the Teaching Establishment

    ERIC Educational Resources Information Center

    Gabriel, Norman

    2016-01-01

    There have been very few studies that apply the work of Mikhail Bakhtin and Norbert Elias to understand the underlying learning processes of young children. This article will explore the methodological similarities between Bakhtin's ideas about the carnivalesque and Norbert Elias's theory of established-outsider relations to explain how young…

  13. Diffractive Optics: Design, Fabrication, and Applications, Technical Digest Series, Volume 9, 1992

    DTIC Science & Technology

    1992-01-01

    Diffractive TuA, DIFFRACTIVE OPTICS FOR LASER SYSTEMS and refractive microlenses are combined to obtain improved Norbert Streibl, University Erlangen...wave linear diode-laser array into a two-dimensional distribution analysis of grating diffraction, Elias N. Glytsis, Thomas K. with symmetric...Diffractive optical elements in optoelectronics, Norbert Streibl, Physikalisches Institut, Germany. Diffractive components such as deflectors, lenses and

  14. A new laboratory instrument for defining near-saturation wetting-drying and capillary conductivity

    NASA Astrophysics Data System (ADS)

    Vache, K.; McDonnell, J. J.; Ekanayake, J.; Graham, C.

    2004-12-01

    The moisture release curve is a fundamental descriptor of soil water movement. While tension table apparatus for defining drainage curves in the near-saturated region (0 to -100 cm H2O) have been available for many decades, there has been little advance in automating the process, particularly when measurements of wetting, drying and capillary conductivity are combined. We describe a new instrument, the Automated Moisture Release Apparatus (AMRA), that uses a precision water flow measurement coupled with an accurately controlled variable hydraulic head to exactly define the relationship between matric potential and volumetric water content? from 0 to -100 cm H2O. The new instrument automates the process without any disturbance to the soil core and and has fully programmable suction steps and equilibration times. We compare AMRA moisture release curve results with published Accusand tests for four different grain size mixtures and under different sample height and volume combinations. Our results are consistent with published results and our tests provide guidance on appropriate core lengths for media characterization. AMRA results from field samples from well-characterized soils at the HJ Andrews Experimental Forest in Oregon are also described. These experiments show both consistent drying behavior and drainable porosity decline with depth in the vadose zone. Overall, the instrument's precision, programmable platform, and combined conductivity and moisture content measurement features, make it a useful tool for estimating soil water storage properties/parameters for use in vadose zone hydrology.

  15. Found Space in a Courtyard

    ERIC Educational Resources Information Center

    Curley, Kenneth

    1974-01-01

    Skyrocketing interest rates and soaring construction costs are taking their toll on college and university building programs. At St. Norbert College in De Pere, Wisconsin, plans are underway to recycle a residence hall for use as a library. (Author)

  16. The Application of USAID and the Department of Defense in a Comprehensive Government Approach

    DTIC Science & Technology

    2013-05-23

    humanitarianism-in-comprehensive-approaches (accessed 15 January 2013). 109Johanna Mendelson Forman and Claude Welch, Civil-Military Relations: USAID’s Role...Johanna Mendelson and Claude Welch. Civil-Military Relations: USAID’s Role (USAID through Associates in Rural Development, Inc, July 1998). http... Mendelson , Johanna Forman, and Claude Welch. Civil-Military Relations: USAID’s Role. USAID through Associates in Rural Development, Inc (July 1998): 5

  17. Robust SERS Enhancement Factor Statistics Using Rotational Correlation Spectroscopy

    DTIC Science & Technology

    2012-05-02

    15. SUBJECT TERMS See attached. Ted A. Laurence , Gary B. Braun, Norbert O. Reich, Martin Moskovits University of California - Santa Barbara 3227...Cheadle Hall 3rd floor, MC 2050 Santa Barbara, CA 93106 -2050 REPORT DOCUMENTATION PAGE b. ABSTRACT UU c. THIS PAGE UU 2. REPORT TYPE New Reprint 17...Spectroscopy Ted A. Laurence ,*,†,§ Gary B. Braun,‡,§ Norbert O. Reich,‡ and Martin Moskovits‡ †Physical and Life Sciences Directorate, Lawrence Livermore

  18. Death, the Military and Society: Casualties and Civil-Military Relations in Germany

    DTIC Science & Technology

    2005-08-01

    has been socially toned down. In this, he is joined by others who - like, inter alia, Norbert Fischer (2001) and the authors in the anthology by Blum...also propelled by processes renowned sociologists like Ulrich Beck, Norbert Elias, Anthony Giddens, and Ronald Inglehart came to call individualization...At around 1:00 p.m. local time on 29 May 2003 German soldiers were driving in two unar- mored Wolf vehicles on patrol in heavy terrain far out from

  19. Roles of Tunneling, Multiphoton Ionization, and Cascade Ionization for Femtosecond Optical Breakdown in Aqueous Media

    DTIC Science & Technology

    2009-09-01

    aqueous media AFOSR International Research Initiative Project SPC 053010 / EOARD Grant FA 8655-05-1-3010 Final Report September 2009 Norbert Linz...performing additional calculations complementing the data base on the dependence of temperature and pressure on internal energy. While Norbert Linz...breakdown in solids. IEEE J Quantum Electron 10:375-386 [Bor70] Born M, Wolf E (1970) Principles of Optics. Pergamon Press: Oxford [Bos93

  20. Geodiversity characterization and assessment of the Morainic Amphitheatre of Rivoli -Avigliana (NW-Italy)

    NASA Astrophysics Data System (ADS)

    Giordano, Enrico; Lucchesi, Stefania; Perotti, Luigi; Giardino, Marco

    2014-05-01

    The concept of Geodiversity in its wide sense refers specifically to particular geosystems that are in themselves complex (e.g diverse) assemblages of bedrock, landform, and soil features. Therefore, geodiversity assessment is strictly related to landscape structure, whose studies are in the field of complex Physical Geography. Moreover, Geodiversity studies provide a fundamental base for geoconservation and environmental management in a holistic way. This is particularly true within complex geomorphological environments, where many intrinsic and extrinsic factors are interconnected. Various procedures has been already applied for the creation of geodiversity maps in different geomorphological context, but especially in wide areas with a large geodiversity of landforms. Pleistocene morainic amphitheatres of the Alpine piedmont regions are indeed particular and complex environments: not only for the geological and geomorphological points of view, but also for their relationships with biotic components and human life. The aim of this study is to carry out a geodiversity characterization of the Rivoli-Avigliana Morainic Amphitheatre (AMRA; NW Italy). The AMRA separates the lower Susa Valley from the middle course of the Sangone River; it is a set of low hills and depressions related to glacial pulsations aged between 750,000 and 12,000 years ago. Earth Sciences knowledge of the area has been compared to detailed field geomorphological and territorial data in order to determine qualitative and quantitative landscape parameters and to evaluate their validity for geodiversity assessment. A first qualitative characterization of the AMRA and an estimation of its geodiversity have been performed by means of geomorphological mapping and stratigraphic studies, including geomorphosites assessment for the same area. Then, geodiversity characterization and evaluation have been performed through the definition and application of quantitative parameters (landform energy, slope

  1. Transparent Glass Ceramics Doped by Chromium(III) and Chromium(III) and Neodymium(III) as New Materials for Lasers and Luminescent Solar Concentrators.

    DTIC Science & Technology

    1987-04-30

    Laboratoire de Physico-Chimie des Materiaux Luminescents Universite Claude Bernard Lyon-Unite associee au CNRS 69622 - Villeurbanne, France Anne-Marie...Bouderbala, Georges Boulon Laboratoire de Physico-Chemie des Materiaux Luminescents Universite Claude Bernard Lyon - Unite associee au CNRS 69622

  2. Chandra Adds to Story of the Way We Were

    NASA Astrophysics Data System (ADS)

    2003-05-01

    consisting of two pairs of stars, called HD 98800A and HD 98800B. These pairs, each of which is about an Earth-Sun distance apart, orbit each other at about the same distance as Pluto orbits the Sun. "Our X-ray results are fully consistent with other observations that show that accretion of matter from a disk in HD 98800A has dropped to a low level," said Kastner. "So Chandra has thrown new weight behind the evidence that any disk in this system has been greatly diminished or destroyed in ten million years, perhaps by the ongoing formation of planets or by the companion stars." The new X-ray technique for studying disks around stars relies on the ability of Chandra's spectrometers to measure the energies of individual X-rays very precisely. By comparing the number of X-rays emitted by hot gas at specific energies from ions such as oxygen and neon, the temperature and density of particles can be determined. This new technique will help astronomers to distinguish between an accretion disk and a stellar corona as the origin of intense X-ray emission from a young star. Other members of the research team are David Huenemoerder, Norbert Schulz, and Claude Canizares from the Massachusetts Institute of Technology, and David Weintraub from Vanderbilt University. NASA's Marshall Space Flight Center in Huntsville, Ala., manages the Chandra program, and TRW, Inc., Redondo Beach, Calif., is the prime contractor for the spacecraft. The Smithsonian's Chandra X-ray Center controls science and flight operations from Cambridge, Mass., for the Office of Space Science at NASA Headquarters, Washington. The image and additional information are available at: http://chandra.harvard.edu and http://chandra.nasa.gov

  3. [Claudio Bernard and fat emulsion (or the Sleeping Beauty 150 years later)].

    PubMed

    Rodríguez de Romo, A C; Borgstein, J

    2000-01-01

    In 1848, Claude Bernard discovered the lipolytic function of the exocrine pancreas. His experimental procedure was very original and he always said that it was easily reproducible. This paper reproduces the experiments that Bernard made on the digestion of fat. The work is original because the experiments were taken from Bernard's personal manuscripts that are unpublished. The paper also deals with Claude Bernard's personal papers. Our results were like Bernard's: his experiments and conclusions were very truthful as well as his ideas on reproducibility in experimental medicine. The surgical part was not simple, so Claude Bernard probably was very skillful.

  4. The Art of Modeling Stars in the 21st Century (IAU S252)

    NASA Astrophysics Data System (ADS)

    Deng, L.; Chan, K. L.

    2008-12-01

    Preface; Organizing committee; Conference participants; Session I. Updates of physical ingredients of stellar models Norbert Langer; Session II. Physical processes in stars Kwing-Lam Chan; Session III. From physics to stars, the progenitors of white dwarfs Vittorio Canuto and Jørgen Christensen-Dalsgaard; Session IV. From physics to stars, the progenitors of neutron stars and black holes Lee Anne Willson and Martin Asplund; Session V. Physics of stars in close binaries Philipp Podsiadlowski and Licai Deng; Session VI. New tools and future perspective Werner Däppen; Summary Norbert Langer; Author index; Subject index.

  5. FNLM Medical Awards | NIH MedlinePlus the Magazine

    MedlinePlus

    ... Choppin, MD, President Emeritus, Howard Hughes Medical Institute Michael E. DeBakey Library Services Outreach Award Ann Duesing, Outreach Librarian, Claude Moore Health Sciences Library, UVA Distinguished Medical ... Citation Michael Lemole, one of the medical professionals who operated ...

  6. Atlantic Oceanography. Volume 2

    DTIC Science & Technology

    1978-08-01

    Gibbs transform fault. 4124 CLAUDE FRANKIGNOUL and TERRENCE M. JOYCE. Internal wave variability during the Internal Wave Experiment (IWEX). 4126 P.L...tions of interaction between the internal wave field and low frequency flows in the North Atlantic. 4124 CLAUDE FRANKIGNOUL and TERRENCE M. JOYCE...tertiary marine benthic gastropods. In Historical Biogeography , Plate Tectonics and the Changing Environment, A. J. Boucot and J. Gray [eds

  7. Polymers Used as Fuel for Laser Plasma Thrusters in Small Satellites

    DTIC Science & Technology

    2007-11-02

    chemical reactions (crosslinking), and the stability of the IR dye during these reactions is doubtful. We have also prepared large coated films for Claude...best” performer in the thruster tests (by Claude Phipps). The chemical structures are shown in Scheme 2. The polymers were studied with two different...2 J. Luque and D.R. Crosley, “LIFBASE: Databse and Spectral Simulation Program (Version 1.5)“, SRI International Report MO 99-009 (1999) 3 I. Kovacs

  8. Project Summaries: Office of Basic Research Contract Program, 1989-1991

    DTIC Science & Technology

    1990-08-01

    University Jean -Claude Falmagne SCIENTIFIC OBJECTIVES: The objective is to design, test and implement computerized knowledge assessment procedures, capable...estimate the effects of variability training on transfer. Results are compared to performances on tests adapted from Piaget and on field dependence...Driskell, James 109 Druckman, D. 177 Falmagne, Jean -Claude 117 Fiedler, Fred 15,34 Fields, Lanny 158 Fischer, Gerhard 91 Frederiksen, John 119 Green

  9. Biomedical engineering degrees at Lyon 1 University.

    PubMed

    Perrin, E; Berger-Vachon, C; Ray, C; Canet-Soulas, E; Hartmann, D; Oudin-Dardun, F; Briguet, A

    2007-01-01

    Biomedical diploma degrees have a long tradition at Lyon 1, Claude Bernard University. Since 2004, the transition towards the LMD system leaded to a unified Bachelor and Master Degree in Biomedical Engineering. A next evolution plans the creation of a Biomedical Engineering Department in the future Polytechnic School of Claude Bernard University. This department will form professionals in Biomedical Engineering, Medical Physics and for academic employment in Universities and research structures.

  10. Continuity and Change in the Experiences of Transition from School to Work

    ERIC Educational Resources Information Center

    Goodwin, John; O'Connor, Henrietta

    2007-01-01

    Using previously unanalysed data from Norbert Elias's lost study of young workers in Leicester--the "Adjustment of Young Workers to Work Situations and Adult Roles" (1962-1964), and data from a subsequent restudy of the same respondents in 2003-2005, this paper focuses on three main themes. First, we critically examine the concept of…

  11. Aurora-A as a Modifier of Breast Cancer Risk in BRCA 1/2 Mutation Carriers

    DTIC Science & Technology

    2007-06-01

    Dieter Schaefer, Institute of Human Genetics, University of Frankfurt, Frankfurt, Germany; Norbert Arnold, University of Schleswig- Holstein , Campus...Intron 2 Opossum Mouse Rat Cow Dog Intron 1 Figure 3 | The FGFR2 locus. a, Map of the whole FGFR2 gene, viewed relative to common SNPs on HapMap

  12. Revista de Documentacao de Estudos em Linguistica Teorica e Aplicada (DELTA): Novos Estudos em Gamatica Gerativa (Journal of Documentary Studies in Theoretical and Applied Linguistics [DELTA]: New Studies in Generative Grammar).

    ERIC Educational Resources Information Center

    Revista de Documentacao de Estudos em Linguistica Teorica e Aplicada, 2000

    2000-01-01

    This issue contains the following articles: "Resumption and Last Resort" (Joseph Aoun); "Existentials, A-Chains, and Reconstruction" (Norbert Hornstein); "How Long Was the Nineteenth Century" (David Lightfoot); "Formal Features and Parameter Setting: A View From Portuguese Past Participles and Romance Future…

  13. Bilingual Competence and Bilingual Proficiency in Child Development

    ERIC Educational Resources Information Center

    Francis, Norbert

    2011-01-01

    When two or more languages are part of a child's world, we are presented with a rich opportunity to learn something about language in general and about how the mind works. In this book, Norbert Francis examines the development of bilingual proficiency and the different kinds of competence that come together in making up its component parts. In…

  14. Handheld Concealed Weapons Detector Development

    DTIC Science & Technology

    2003-03-01

    Enforcement, Edward M. Carapezza, Donald Spector, Eds., Proc. SPIE 2938, 110 - 119 (1997). 3. Franklin Felber, Norbert Wild, Scott Nunan , Dennis Breuner... Nunan , D. Breuner, and F. Doft, "Handheld Ultrasound Concealed-Weapons Detector," in Enforcement and Security Technologies, A. Trent DePersia, J. J

  15. Using Agent Based Distillation to Explore Issues Related to Asymmetric Warfare

    DTIC Science & Technology

    2009-10-01

    hierarchical model of needs proposed by Abraham Maslow [12]. An interpretation of Maslow’s hierarchy of needs can be represented as a pyramid with the more...D. Kahnemann, E. Deiner, Dr. Phil Norbert Schwarz, « Foundations of Hedonic Psychology », Russell Sage Foundation, 1999 [12] Abraham.H. Maslow

  16. Out of a creative jumble of ideas in the middle of last Century: Wiener, interdisciplinarity, and all that.

    PubMed

    Montagnini, Leone; Tabacchi, Marco Elio; Termini, Settimo

    2016-01-01

    Is Biophysics an interdisciplinary science? In order to answer this rhetorical question, it can be useful to look back at history of disciplines, as well as that of the scientific institutions helping their development. In this contribution some aspects of the unusual hodgepodge of concepts involving Biophysics, the legacy of Cybernetics, cognitive science and the central figure of Norbert Wiener are presented and discussed.

  17. Adult and Child Identities in Irish Primary Schools, c.1830-1909

    ERIC Educational Resources Information Center

    Dolan, Paddy

    2016-01-01

    Drawing on teaching manuals, government reports and school inspectors' reports from the 1830s up to the early twentieth century, this paper traces the changing conceptual and social distance between childhood and adulthood in Ireland. Using Norbert Elias's figurational approach, it is argued that children became increasingly involved in both…

  18. "Una Communita" Poco Nota della Communicazione non Verbale: Come Communicano il Direttore e l'Orchestra (A Little Known "Community" of Nonverbal Communication: How the Conductor and Orchestra Communicate).

    ERIC Educational Resources Information Center

    Leonardi, Magda Farago

    1992-01-01

    Examines how conductors and orchestras communicate. Communication is essentially nonverbal. Conductors use gestures, gaze, facial expression, nods and posture to deliver their message. Norbert Weiner's Cybernetic Theory of human communication is seen as a means of analyzing precisely how this musical communication takes place. (16 references) (LET)

  19. Identifying Configurations of Higher Education: Reflections on Concepts That Compare Complex Cultural Settings

    ERIC Educational Resources Information Center

    Alheit, Peter

    2013-01-01

    This paper examines the idea of qualitative comparing in order to create a "heuristic concept" that will enable relational structures to be examined, drawing on the sociological tradition founded by Norbert Elias. Subsequently, an empirical research example -- the comparison of three "mentality spaces" in post-socialist…

  20. Configurations of Activity: From the Coupling of Individual Actions to the Emergence of Collective Activity. A Study of Mathematics Teaching Situation in Primary School

    ERIC Educational Resources Information Center

    Veyrunes, Philippe; Gal-Petitfaux, Nathalie; Durand, Marc

    2009-01-01

    This article presents and uses the notion of configuration of activity, which extends the Norbert Elias's original concept of social configuration based on the study and analysis of individual and collective activity. Although this concept embraces all types of social activities, in the present study the authors used it to describe and analyse…

  1. "I Couldn't Wait for the Day": Young Workers' Reflections on Education during the Transition to Work in the 1960s. CLMS Working Paper.

    ERIC Educational Resources Information Center

    Goodwin, John; O'Connor, Henrietta

    Researchers analyzed 500 never-before-analyzed interviews from a study conducted by Norbert Elias and other researchers at University of Leicester in 1962, which was one of the first studies of the transition from school to work. The Elias study explored how young people in England experienced work and adjusted their lives to the work role. All of…

  2. Wavelength Dependence of Nanosecond IR Laser-Induced Breakdown in Water: Evidence for Multiphoton Initiation via an Intermediate State

    DTIC Science & Technology

    2015-04-29

    Wavelength dependence of nanosecond IR laser-induced breakdown in water: evidence for multiphoton initiation via an intermediate state Norbert...band. Theoretical analysis based on these assumptions suggests that the seed electron density required for initiating avalanche ionization drops from...powerful for supporting higher order multiphoton processes [15-18]. However, conclusive evidence for the relevance of photoionization in ns breakdown is

  3. The Pragmatist Reader: Reading as a Meaning-Making Transaction in the English Classroom

    ERIC Educational Resources Information Center

    Taylor, Stephen

    2011-01-01

    Rosenblatt's transactional theory and Pike's aesthetic model of reading both put the reader at the heart of the reading transaction. A re-envisionment of these approaches in terms of the pragmatist reader, a concept derived from Norbert Wiley's "pragmatism's self" and the findings of a recent case study into classroom reading, leads to a…

  4. Within the Shadows.

    ERIC Educational Resources Information Center

    Griffin, Noah

    1989-01-01

    Discusses why Black inventors historically were not recognized by society and the consequences of this discrimination. Covers the following inventors who defied the odds and beat the stereotype to invent important items: (1) Norbert Rillieux; (2) Jan Ernst Matzeliger; (3) Granville T. Woods; and (4) Garrett A. Morgan. (JS)

  5. Molecular Modeling and Experimental Study of Electrocatalytic and Transport Processes in High Temperature Polymer Electrolyte Fuel Cells

    DTIC Science & Technology

    2005-12-15

    Proteins, Lecture Notes, Norbert Attig, Kurt Binder, Helmut Grubm’" uller, Kurt Kremer (Eds.), John von Neumann Institute for Computing, J - ulich, NIC...34, Materials Letters, 52, 192-196 (2002). 10. Accelrys, http://www.accelrys.com/about/msi.html 11. K.L.Yeung, E.E. Wolf , J.Catal. 13, 135(1992). 12. S. Lee

  6. Seaworthy Quantum Key Distribution Design and Validation (SEAKEY)

    DTIC Science & Technology

    2014-04-25

    with Norbert Lutkenhaus, Saikat Guha found a fundamental difference between the rates of direct-secure communication and QKD. The former is higher with...receiver Field of view REFERENCES 1. William Wolfe and George Zissis, Infrared Handbook, Office of Naval Research, Department of the Navy

  7. Internationalization, Globalization and Relationship Networks as an Epistemological Framework Based on Comparative Studies in Education

    ERIC Educational Resources Information Center

    García, Amelia Molina; Lara, José Luis Horacio Andrade

    2016-01-01

    In this paper we present some thoughts on the epistemological framework of comparative studies in education. We present some concepts on the internationalization, globalization and inter-relation networks, based on Jürgen Schriewer, Immanuel Wallerstein, and Norbert Elias's theoretical concepts. These reflections were built within the framework of…

  8. Thermodynamic design of natural gas liquefaction cycles for offshore application

    NASA Astrophysics Data System (ADS)

    Chang, Ho-Myung; Lim, Hye Su; Choe, Kun Hyung

    2014-09-01

    A thermodynamic study is carried out for natural gas liquefaction cycles applicable to offshore floating plants, as partial efforts of an ongoing governmental project in Korea. For offshore liquefaction, the most suitable cycle may be different from the on-land LNG processes under operation, because compactness and simple operation are important as well as thermodynamic efficiency. As a turbine-based cycle, closed Claude cycle is proposed to use NG (natural gas) itself as refrigerant. The optimal condition for NG Claude cycle is determined with a process simulator (Aspen HYSYS), and the results are compared with fully-developed C3-MR (propane pre-cooled mixed refrigerant) JT cycles and various N2 (nitrogen) Brayton cycles in terms of efficiency and compactness. The newly proposed NG Claude cycle could be a good candidate for offshore LNG processes.

  9. Quantitative Electron Probe Microanalysis Using a Scanning Electron Microscope and an X-Ray Energy Spectrometer.

    DTIC Science & Technology

    1980-04-01

    necessary to solve the ZAF cor- rections in an iterative manner similar to that used by J . Colby 13in the Magic IV programme . In that programme the...Combined with an Energy Dispersive X-ray Analyzer for Quantitative Analysis", X-ray Spectrometry, 2, 1973. 10. Green, L.: Journ. of Phys. E. Scient ... Instrum ., 2, (3), 1973. 11. Wodke, Norbert F. and Schamber, Frederick, MS 885 Super ML Operation and Programme Description Version 1, Unpublished, Tracor

  10. JPRS Report, West Europe.

    DTIC Science & Technology

    2007-11-02

    recent positive portrayal of Gorbachev has been replaced by a picture of a wolf in sheep’s clothing. Nobody is satisfied with the perceived opinion... Norbert de Batselier, Marcel Colla, Piet van Eeckhaut, and Luc Van den Bossche— had different ideas, ideas that clashed with what the strong-minded old...hastily compiled legislation could become a " wolf ". An immediate proposal would also have meant that it would have become neces- sary to move the

  11. The Coherence of Acoustic Signals in the Ocean and Application to the Design of Very Large Arrays

    DTIC Science & Technology

    1979-01-01

    rediscovery by Mandel and Wolf [8] in 1976i First introduced in time series analysis by Wiener [9] in 1930, it is defined as the cross-power spectral...Theory of Partial Coherence, Prenticez-Hall, Inc.:, Englewood Cliffs, N.J., 1964. (8] L. Mandel, E. Wolf , "Spectral Coherence and the Concept of...Selected Paners of Norbert Wiener, MIT Press, Cambridge, Massachusetts, 1964. *"[10] L. H. Koopmans, The Spectral Analysis of Time Series, Academic Press

  12. EGFR-Dependent Regulation of Matrix-Independent Epithelial Cell Survival

    DTIC Science & Technology

    2006-04-01

    invasion through modulation of integrin-mediated adhesion Weitian Zhang1,*, Addy Alt-Holland1,*, Alexander Margulis1, Yulia Shamis1, Norbert E. Fusenig2...play central roles in tumor cell adhesion, migration, invasion, and metastasis (Cavallaro and Christofori, 2004; Friedl and Wolf , 2003). Recent...P. and Wolf , K. (2003). Tumour-cell invasion and migration: diversity and escape mechanisms. Nat. Rev. Cancer 3, 362-374. Frisch, S. M. and Francis

  13. Effects of Low-Level Exposure to Sarin and Cyclosarin During the 1991 Gulf War on Brain Function and Brain Structure in US Veterans

    DTIC Science & Technology

    2006-01-01

    but more prevalent in deployed veterans than in nondeployed veterans (Steele 2000; Unwin et al. 1999; Wolfe et al. 2002). In the present study...analyses, Drs. Norbert Schuff, Susanne Mueller, and Ron Killiany for helpful comments, and Larry Sippos, Executive Chao et al., 26 Officer to the... Wolfe J, Borgos MS, Davis JD, et al. Health status of Persian Gulf War veterans: self-reported symptoms, environmental exposures and the effect of

  14. NATO CBRN Medical Working Group Table Top Exercise on International Health Regulations: Documentation and Output

    DTIC Science & Technology

    2014-05-01

    IDA • Small Group 3: Facilitator – Dr. Herbert Wolfe , U.S. Navy; Recorder – Ms. Julia Burr, IDA. In addition, two subject matter experts, Dr...Faix Dr. Audrey Kelley Mr. Richard Prouty Lieutenant Commander Thad Sharp Mr. James Smith Dr. Herbert Wolfe Colonel Timothy Woodruff Commands... Norbert Holysz Non-NATO Nations Austria Colonel Alois Benc Serbia Colonel Srdjan Lazic Prof. Branka Djurovic Switzerland Colonel Sergei Bankoul

  15. West Europe Report.

    DTIC Science & Technology

    2007-11-02

    REPORT CONTENTS POLITICAL AUSTRIA • Hainburg Controversy Damages Sinowatz Standing (Josef Votzi, Franz Ferdinand Wolf ; PROFIL, 31 Dec 84) .. 1...Votzi and Franz Ferdinand Wolf : "Crisis Chancellor, Chancellor Crisis"] ["Text] It is all very complicated. Sinowatz has scheduled a press con...debate between Minister for Social Administration Dallinger and self-proclaimed Dallinger foe Norbert Steger as well as Salzburg Governor Wilfried

  16. Simplified Helium Refrigerator Cycle Analysis Using the `Carnot Step'

    NASA Astrophysics Data System (ADS)

    Knudsen, P.; Ganni, V.

    2006-04-01

    An analysis of the Claude form of an idealized helium liquefier for the minimum input work reveals the `Carnot Step' for helium refrigerator cycles. As the `Carnot Step' for a multi-stage polytropic compression process consists of equal pressure ratio stages; similarly for an idealized helium liquefier the `Carnot Step' consists of equal temperature ratio stages for a given number of expansion stages. This paper presents the analytical basis and some useful equations for the preliminary examination of existing and new Claude helium refrigeration cycles.

  17. A Weather Analysis System for the Baja California Peninsula: Tropical Cyclone Season of 2008

    NASA Astrophysics Data System (ADS)

    Farfán, L. M.

    2009-05-01

    General characteristics of tropical weather systems are documented on a real-time basis. This study covers the warm season of 2008, from May through November, and includes observations from satellite imagery as well as reports from a rain-gauge network. During this season, the basin had 16 tropical storms and three of them made landfall in the Baja California peninsula, in northwestern Mexico. Tropical storm Julio developed in August and tropical storm Lowell made landfall in mid-September. Norbert, in early October, was the most intense hurricane of the season with strong winds and heavy rainfall that caused significant damage to the infrastructure in the southern peninsula. By the next day, the system moved over the mainland, causing major flooding in Sinaloa, Sonora, and Chihuahua. By request of the Baja California government, a meteorological perspective associated with the structure, intensity, and motion of Hurricane Norbert was presented. This consisted of high-resolution satellite imagery used to explain the spatial and temporal patterns of convection. This material provided an integral analysis of Norbert's behavior during its approach and passage over land, and it was one element, used by emergency managers, to determine the extent of the affected areas.

  18. Travaux Neuchatelois de linguistique (Neuchatel Working Papers in Linguistics).

    ERIC Educational Resources Information Center

    Neuchatel Univ. (Switzerland). Inst. de Linguistique.

    This collection of working papers in linguistics includes four works. "Autour de la racine indo-europeenne 'pet-' ('voler') (pour servir a l'histoire des faits latins)" ("Concerning the Indo-European Root 'Pet-' ('To Fly') (To Serve as an Example of Latin Facts)" by Claude Sandoz looks at the Latin manifestations of the root and illustrates the…

  19. Videotape Recording of Narcotic Addicts in Group Therapy: The Analysis of Communicational and Interactive Behavior.

    ERIC Educational Resources Information Center

    Soloway, Irv

    An approach to the study of drug sub-culture groups and a model for predictive research in the identification and isolation of heroin addicts are developed in this thesis. The basic methodologies employed are the linguistic methods of Kenneth Pike and Claude Levi-Strauss for use in the analysis of social phenomena. Communicative mechanisms by…

  20. Elder Abuse. Hearing before the Subcommittee on Health and Long-Term Care of the Select Committee on Aging. House of Representatives, Ninety-Ninth Congress, First Session.

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. House Select Committee on Aging.

    This document contains testimony and prepared statements from a Congressional hearing called to examine the issue of elder abuse. Chairman Claude Pepper's opening statement discusses the horror of elder abuse and calls for federal legislation, similar to the child abuse legislation, for combating elder abuse. Elder abuse is defined as physical…

  1. Federal Drug Law Enforcement and Interdiction. Hearing before the Select Committee on Narcotics Abuse and Control. House of Representatives, Ninety-Eighth Congress, Second Session, May 22, 1984.

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. House Select Committee on Narcotics Abuse and Control.

    This document contains testimony and prepared statements from the Congressional hearing on federal drug law enforcement. Statements are given from Congressman Claude Pepper, the staff director of the National Narcotics Border Interdiction System (NNBIS), an administrator from the Drug Enforcement Administration (DEA), a commissioner from the…

  2. [The sense of the senseless, psychoanalytic aspects of delusion in psychosis].

    PubMed

    Chaperot, Christophe

    2011-01-01

    The psychoanalytic approach to delusion in psychosis leads us to examine the function of a "furrow". It is necessary to remain in the furrow in order not to become delusional. References to Sigmund Freud, Jacques Lacan, Mélanie Klein and Jean-Claude Maleval enlighten us as to the origin and the function of delusion as an attempt to give meaning.

  3. Long-Term Care: Need for a National Policy. Hearing before the Subcommittee on Health and Long-Term Care of the Select Committee on Aging. House of Representatives, Ninety-Eighth Congress, First Session (December 15, 1983, San Francisco, California).

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. House Select Committee on Aging.

    This document contains transcripts of witness testimony and prepared statements from the Congressional hearing called to review the need for a national health care policy for long-term care. Opening statements are presented from committee chairman Claude Pepper and from Representatives Sala Burton and Barbara Boxer. Testmonies are presented from…

  4. On the Shoulders of Giants: From Boole to Shannon to Taube: The Origins and Development of Computerized Information from the Mid-19th Century to the Present.

    ERIC Educational Resources Information Center

    Smith, Elizabeth S.

    1993-01-01

    Describes the evolution of computerized information storage and retrieval from its mid-nineteenth century beginnings in theoretical works on logic by George Boole, to the applications of Boole's logic to switching circuits by Claude Shannon in the 1930s, to the development of coordinate indexing by Mortimer Taube in the 1940s and 1950s. (Contains…

  5. Poststructuralism as Theory and Practice in the English Classroom. ERIC Digest.

    ERIC Educational Resources Information Center

    Bush, Harold K., Jr.

    This digest provides a historical review of some current literary theories and practices which developed from contemporary philosophy. Structuralism, associated with Ferdinand de Saussure and Claude Levi-Strauss, with a seemingly scientific view of language and culture posited a systemic "center" that organized and sustained an entire…

  6. The XIIIth International Physiological Congress in Boston in 1929: American Physiology Comes of Age

    ERIC Educational Resources Information Center

    Rall, Jack A.

    2016-01-01

    In the 19th century, the concept of experimental physiology originated in France with Claude Bernard, evolved in Germany stimulated by the teaching of Carl Ludwig, and later spread to Britain and then to the United States. The goal was to develop a physicochemical understanding of physiological phenomena. The first International Physiological…

  7. Levi-Strauss's "Bricolage" and Theorizing Teachers' Work.

    ERIC Educational Resources Information Center

    Hatton, Elizabeth

    1989-01-01

    A teacher's work is compared to Claude Levi-Strauss's concept of "bricolage." A "bricoleur" is a professional do-it-yourself person, falling somewhere between an odd-job person and a craftsperson. The concept helps to explain pedagogical inadequacy by linking inherent limiting features of teachers' work and some causal…

  8. Linking Stereotype Threat and Anxiety

    ERIC Educational Resources Information Center

    Osborne, Jason W.

    2007-01-01

    Claude Steele's stereotype threat hypothesis has attracted significant attention in recent years. This study tested one of the main tenets of his theory--that stereotype threat serves to increase individual anxiety levels, thus hurting performance--using real-time measures of physiological arousal. Subjects were randomly assigned to either high or…

  9. Gender, Stereotype Threat, and Anxiety: Psychophysiological and Cognitive Evidence

    ERIC Educational Resources Information Center

    Osborne, Jason W.

    2006-01-01

    Introduction: Claude Steele's stereotype threat hypothesis proposed that negative group stereotypes increase individual anxiety levels, hurting performance. However, the role of anxiety in stereotype threat has not been fully explored. This study examined the hypothesis that experimental manipulation of stereotype threat would influence real-time…

  10. High-Current Density, High-Brightness Electron Beams from Large-Area Lanthanum Hexaboride Cathodes.

    DTIC Science & Technology

    1987-12-13

    Clarendon, Oxford, 1977), Chaps. 4.3-4.4. 15. Claude Lejeune and Jean Aubert, in Applied Charged Particle Optics, edited by A. Septier (Academic, New...Applications Intl. Corp. 1710 Goodridge Drive McLean, VA 22102 Dr. Charles C. Damm Lawrence Livermore National Laboratory P.O. Box 808 Livermore, CA 94550

  11. Intelligent Automated Process Planning and Code Generation for Computer-Controlled Inspection

    DTIC Science & Technology

    1994-01-01

    Overview of Exact and Approximate Algorithms," European Journal of Operational Research, 59, 231-247. Latombe, Jean - Claude , 1991. Robot Motion Planning...points must occur in a specific or- der. regardless of distance. The direction of the normal of the primary, secondary, and tertiary damms are

  12. Sartre: A Collection of Critical Essays. Twentieth Century Views Series.

    ERIC Educational Resources Information Center

    Kern, Edith, Ed.

    One of a series of works aimed at presenting contemporary critical opinion on major authors, this collection includes essays by Edith Kern, Claude-Edmonde Magny, Henri Peyre, Kenneth Douglas, Edmund Wilson, Theophil Spoerri, Jacques Guicharnaud, Eric Bentley, Robert Champigny, Oreste F. Pucciani, Frederic Jameson, Rene Girard, Guido…

  13. Arctic Ozone Loss in Threshold Conditions: Match Observations in 1997/1998 and 1998/1999

    DTIC Science & Technology

    2001-04-16

    Kiihlungsborn, Germany. 8Instituto Nacional de Meteorologia , Madrid, Spain. 9Deutscher Wetterdienst, HohenpeiBenberg, Germany. 10Instituto Nacional de... Meteorologia , Tenerife, Spain. 11 Atmospheric Environment Service, Downsview, On- tario, Canada. 12Royal Meteorological Institute, Brussels, Belgium...Nacional de Meteorologia , Apdo. 285, 28071 Madrid, Spain. (Jmin.Cisneros@inm.es) H. Claude, DWD, Observatory HohenpeiBenberg, Albin- Schwaiger-Weg 10

  14. Native Sons: A Critical Study of Twentieth-Century Negro American Authors.

    ERIC Educational Resources Information Center

    Margolies, Edward

    This analysis of 20th-century Negro literature contains chapters discussing 16 authors: (1) "The First Forty Years: 1900-1940," including W. E. B. DuBois, Charles W. Chesnutt, James W. Johnson, Paul L. Dunbar, Langston Hughes, Jean Toomer, Claude McKay, and Countee Cullen; (2) "Migration: William Attaway and 'Blood on the Forge'"; (3) "Richard…

  15. Studies of Phase-Conjugate Optical Device Concepts

    DTIC Science & Technology

    1989-03-01

    Electron. 10, 356 (1980). show good reproduction of the polarization of the incident 10. L. Chase, M. Claude, D. Hulin , and A. Mysyrowicz Phys. Rev. A wave...into a Referring to Fig. 1, we consider a phase-conjugate Michel - crystal of barium titanate to provide the pumping waves for son interferometer 9

  16. An Evolution in Student-Centered Teaching

    ERIC Educational Resources Information Center

    Goodman, Barbara E.

    2016-01-01

    The American Physiological Society (APS) Teaching Section annually honors an educator through its Claude Bernard Distinguished Lecture at the Experimental Biology meeting. Since I knew about my selection for almost a year, I had a long time to think about what I wanted to say and how I wanted to say it. The theme of my presentation was…

  17. A Physiologist's View of Homeostasis

    ERIC Educational Resources Information Center

    Modell, Harold; Cliff, William; Michael, Joel; McFarland, Jenny; Wenderoth, Mary Pat; Wright, Ann

    2015-01-01

    Homeostasis is a core concept necessary for understanding the many regulatory mechanisms in physiology. Claude Bernard originally proposed the concept of the constancy of the "milieu interieur," but his discussion was rather abstract. Walter Cannon introduced the term "homeostasis" and expanded Bernard's notion of…

  18. Modern Impressions

    ERIC Educational Resources Information Center

    Simkus, Joyce

    2010-01-01

    Claude Monet and the Impressionists were the forward thinkers and painters of their time. They used quick brushstrokes and a rapid pace to capture lively outdoor scenes. Inspired by the colors and shadows revealed by sunlight, the Impressionists typically worked outside, without many preliminary sketches or drafts. This was in direct contrast to…

  19. Mariculture Potential Along the Northern Gulf Coast,

    DTIC Science & Technology

    Species on which mariculture experiments have been conducted in Alabama either command a high price for food or bait, represent depressed natural...Alabama’s Claude Peteet Mariculture Center (CPMC). Polyculture experiments with penaeid shrimp and pompano have produced combined weights of 1023 kg/ha

  20. Endeavour returns from Hubble servicing

    NASA Astrophysics Data System (ADS)

    1993-12-01

    During the hour-long descent from space ESA astronaut Claude Nicollier helped mission commander Dick Covey and pilot Ken Bowersox monitor the shuttle's cockpit displays. During their 11-day mission the astronauts fitted the telescope with corrective optics and a new set of European solar panels. If all goes according to plan the observatory will be restored to very nearly its original capability. The first images from the rejuvenated telescope should be released in about 6-8 weeks. ESA had a major role in this mission. In addition to providing the solar arrays, the European Space Agency helped NASA test the Costar corrective optics system. ESA astronaut Claude Nicollier operated the shuttle's robot arm throughout the complex spacewalks to service the telescope and during the crucial capture and release phases. "This was a particularly important international mission from the standpoint of our Swiss and European Space Agency crew member Claude Nicollier, who played an incredibly important part in the repair of the Hubble Space Telescope", mission commander Dick told Swiss Minister of Internal Affairs Mrs Ruth Dreifuss, during a VIP telephone call on Sunday morning. "If there was an unsung hero of this mission it would be Claude and his arm because without them we could not have worked the way we did and been as successful as we were".

  1. ESA MS Nicollier, assisted by technicians, dons EMU lower torso in JSC's WETF

    NASA Technical Reports Server (NTRS)

    1987-01-01

    European Space Agency (ESA) Mission Specialist (MS) Claude Nicollier, seated and wearing a liquid cooling and ventilation garment (LCVG), pulls on the extravehicular mobility unit (EMU) lower torso as a technician straightens the EMU leg. Nicollier is preparing for an underwater extravehicular activity (EVA) simulation and familiarization session in JSC's Weightless Environment Training Facility (WETF) Bldg 29 pool.

  2. APS at 125: A Look Back at the Founding of the American Physiological Society

    ERIC Educational Resources Information Center

    Ryan, Kathy L.

    2013-01-01

    Early efforts in physiological research in the United States were produced by lone investigators working in laboratories funded by their own medical practices. In Europe, however, Claude Bernard and Carl Ludwig produced a new model of scientific research laboratories funded by the state that sought to develop the pursuit of biomedical research as…

  3. Safety and Efficacy of Over-the-Counter Drug Use by the Elderly. Hearing before the Subcommittee on Health and Long-Term Care of the Select Committee on Aging. House of Representatives, Ninety-Eighth Congress, First Session.

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. House Select Committee on Aging.

    This document contains the prepared statements and panel testimony from the Congressional hearing on over-the-counter (OTC) drug use by the elderly. Opening statements are given by Representatives Claude Pepper (chairman), Ralph Regula, Mary Rose Oakar, Michael Bilirakis, Tom Lantos, and Hal Daub. Topics which are covered include the incidence and…

  4. Ability Is Ageless. Hearing before the Subcommittee on Health and Long-Term Care of the Select Committee on Aging. House of Representatives, Ninety-Ninth Congress, Second Session.

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. House Select Committee on Aging.

    This document presents the text of a hearing on the relationship of ability to age, in reference to removing age caps so that age will be irrelevent to getting and keeping a job. Statements by Representatives Ron Wyden, Claude Pepper, Ralph Regula, Bill Schuette, Jim Lightfoot, Ike Skelton, George Wortley, and Don Bonker are included. Testimony by…

  5. Catastrophic Health Insurance: The Tennessee Perspective. Hearing before the Subcommittee on Health and Long-Term Care of the Select Committee on Aging. House of Representatives, Ninety-Ninth Congress, Second Session (Chattanooga, Tennessee).

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. House Select Committee on Aging.

    This document contains witnesses' testimonies and prepared statements from the Congressional hearing held in Chattanooga, Tennessee to gain that state's perspective on catastrophic health insurance. Opening statements are included from Representatives Marilyn Lloyd and Claude Pepper. Two panels of witnesses provide testimony. The first panel,…

  6. Integrate the Arts. Monet's Garden Pops Up!

    ERIC Educational Resources Information Center

    Parks, Mary

    1996-01-01

    This article outlines the steps in an art activity on the elements of landscapes and touches on the topic of perspective. In the activity students create three-dimensional secret gardens of their own out of construction paper. The activity is based on Claude Monet's painting and his garden in Giverny (Normandy, France). (SM)

  7. Retreat to Eden: Time and the Cosmos in Monet's Images of Giverny.

    ERIC Educational Resources Information Center

    Call, Michael

    1997-01-01

    Attempts to explain Claude Monet's obsession with water lilies in the last 25 years of his life through an interdisciplinary approach combining ideas from the history of landscape design, social history, and anthropology. Offers Monet's gardens at Giverny (France), his series paintings, and the railroad as some possible influences on his painting.…

  8. Peut-on ne pas etre eclectique? (Can We Not Be Eclectic?)

    ERIC Educational Resources Information Center

    Le Goffic, Pierre

    1977-01-01

    An interview with Jean-Claude Chevalier in which the advantages and dangers of eclecticism are discussed. Some topics covered are: the role of traditional grammar; recent linguistic research in French; the development of teaching methods; Chomsky's theory of universal grammar. (Text is in French.) (AMH)

  9. Actes des Journees de linguistique (Proceedings of the Linguistics Conference) (13th, Quebec, Canada, March 25-26, 1999).

    ERIC Educational Resources Information Center

    Kavanagh, Eric, Ed.

    Papers on language research in this volume include the following: Pour une comparaison des voyelles nasals du Quebec et du Haut-Jura: observations, methodologie et outils infomatiques (A Comparison of Quebec and Haut-Jura's Nasal Vowels: Observations, Methodologies, and Instrumentation) (Vincent Arnaud and Claude Paradis); Le negociation du sens…

  10. Central African Security: Conflict in the Congo

    DTIC Science & Technology

    2002-01-01

    Alliances mouvantes et conflits extraterritoriaux en Afrique Centrale. Paris: L’Hamarttan. Jean-Claude Willame, Banyarwanda et Banyamulenge: Violence...ethnique et gestion de l’identitaire au Kivu. Paris; L’Harmattan, 1997. Crawford Young, “Zaire: The Anatomy of a Failed State,” in David Birmingham & Phyllis

  11. Workers' Attitudes to Technical Change: An Integrated Survey of Research. Industrial Relations Aspects of Manpower Policy 2.

    ERIC Educational Resources Information Center

    Touraine, Alain; And Others

    Methods for encouraging positive worker attitude and behavior toward change were examined to provide a basis for re-evaluation of current policies and programs relating to introduction of technological changes. The literature reviewed is presented in sections of: (1) "The Worker and the Occupational System," by Claude Durand, (2)…

  12. Calculating the Information Content of an Information Process for a Domain Expert Using Shannon's Mathematical Theory of Communication: A Preliminary Analysis.

    ERIC Educational Resources Information Center

    Cole, Charles

    1997-01-01

    Discussion of information as a process focuses on a conceptual exercise for calculating the information content of an information process. Topics include Bertram Brookes' fundamental equation; Claude Shannon's mathematical theory of communication; set of a priori alternatives; knowledge structures; and an example of an archaeologist's information…

  13. Stereotype Threat, Identification with Academics, and Withdrawal from School: Why the Most Successful Students of Colour Might Be Most Likely to Withdraw

    ERIC Educational Resources Information Center

    Osborne, Jason W.; Walker, Christopher

    2006-01-01

    Claude Steeles' stereotype threat hypothesis posits that when there are negative stereotypes about the intellectual capacity of certain (stigmatised) groups, members of that group suffer aversive consequences; group members who are most strongly identified with the stigmatised domain in question (e.g., intellectual or academic ability) are those…

  14. Perfectible Apes in Decadent Cultures: Rousseau's Anthropology Revisited

    ERIC Educational Resources Information Center

    Wokler, Robert

    1978-01-01

    Briefly discusses the views of Claude Levi-Strauss and Robert Ardrey who cite Rousseau as a personal influence even though they hold opposing anthropological ideals. The author claims that this situation is due to misinterpretations of Rousseau's work. An interpretation of Rousseau's anthropology is given reconciling the differences. (BC)

  15. International Symposium on Molecular Spectroscopy (46th) Held in Columbus, Ohio on 17-21 June 1991,

    DTIC Science & Technology

    1991-07-01

    ISOCYANOGEN, CNCN............................ 15 min.(1;59) F. STROH and M. WINNEWISSER, Physikaliach Cheminches Inatitut, Justus - Liebig -Universitat, D...WINNEWISSER, and B. P. WINNEWISSER, Physikalisch-Chemisches Institut, Justus - Liebig -Universitat, D-6300 Giessen, Germany. TA3. IR SPECTROSCOPY WITH A...Sears, Brookhaven; David Skatrud, ARO; Manfred Winnewisser and Brenda Winnewisser, Justus Liebig Universitat; Claude Woods, University of Wisconsin

  16. Abuses in Guardianship of the Elderly and Infirm: A National Disgrace. A Briefing by the Chairman of the Subcommittee on Health and Long-Term Care of the Select Committee on Aging. House of Representatives, One Hundredth Congress, First Session (September 25, 1987).

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. House Select Committee on Aging.

    This document presents a briefing by Representative Claude Pepper on the abuses in guardianship of the elderly and infirm, and testimony from witnesses at the Congressional hearing called to examine the issue of guardianship abuse. The opening statement of Representative Pepper and a prepared statement of Representative Helen Delich Bentley are…

  17. Long-Term Care Insurance: Coverage Varies Widely in a Developing Market. Report to the Chairman, Subcommittee on Health and Long-Term Care, Select Committeee on Aging, House of Representatives.

    ERIC Educational Resources Information Center

    General Accounting Office, Washington, DC. Div. of Human Resources.

    In response to a request by Congressman Claude Pepper, the General Accounting Office (GAO) conducted a study to examine the private long-term care insurance market. The GAO analyzed the premiums, benefits, and limitations of 33 policies offered by 25 insurers in 1986. The GAO assessed the potential for abuse in this market by surveying state…

  18. A Course Connecting Astronomy to Art, History, and Literature

    ERIC Educational Resources Information Center

    Olson, Don

    2015-01-01

    For the past 20 years the author has taught an Honors College course combining astronomy and the humanities. The purpose of this note is to give examples of methods that can be adapted to classroom use for topics including night sky paintings by Vincent van Gogh, Edvard Munch, and Claude Monet, historical events influenced by astronomical factors,…

  19. The Attempted Dismantling of the Medicare Home Care Benefit. A Report by the Chairman of the Subcommittee on Health and Long-Term Care of the Select Committee on Aging. House of Representatives, Ninety-Ninth Congress, Second Session.

    ERIC Educational Resources Information Center

    Pepper, Claude

    This document presents Congressman Claude Pepper's report on the Medicare Home Care Benefit. Section I traces the history of home health care in the United States. Section II offers statistics and general background information about older Americans and Medicare. The beginning of the Medicare home care benefit and its present operation are…

  20. Promoting Learning for Culturally and Linguistically Diverse Students. Classroom Applications from Contemporary Research.

    ERIC Educational Resources Information Center

    Gersten, Russell M.; Jimenez, Robert T.

    This collection of essays is designed to help teachers of linguistically and culturally diverse students address their students' needs effectively. Essays include: "A Balanced Approach to Early Spanish Literacy Instruction" (Claude Goldenberg); "Language and Preliteracy Development of English as a Second Language Learners in Early…

  1. Kindergarten Monets

    ERIC Educational Resources Information Center

    Dionne, Suzanne

    2012-01-01

    Integrating art with literature and science enhances students' learning and retention. Whenever possible, the introduction of the author's art lessons include a relevant artist, such as Claude Monet. In this article, kindergartners paint a pond and learn how to make water lilies using colored tissue-paper squares. (Contains 4 resources.)

  2. Alcohol and the Elderly. Hearing before the Subcommittee on Health and Long-Term Care of the Select Committee on Aging. House of Representatives, Ninety-Eighth Congress, First Session (June 10, 1983, Astoria, N.Y.).

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. House Select Committee on Aging.

    The proceedings of the Congressional hearing on alcohol and the elderly are presented. Following introductory statements by the committee chairman, Senator Claude Pepper, and Representatives Mario Biaggi and Geraldine Ferraro, the briefing paper, "Crisis in Health Care Part 2: Alcoholism," prepared by the subcommittee staff is presented.…

  3. Evolution of an Educator: Lessons Learned and Challenges Ahead

    ERIC Educational Resources Information Center

    Modell, Harold I.

    2004-01-01

    In selecting a Claude Bernard Distinguished Lecturer, the Teaching Section looks for an individual who has made major contributions to physiology education. Dr. Harold Modell has certainly earned this honor. Harold has an undergraduate degree from the University of Minnesota, a Masters in biomedical engineering from Iowa State, and, continuing the…

  4. Actes des Journees de linguistique (Proceedings of the Linguistics Conference) (12th, Quebec City, Canada, March 26-27, 1998).

    ERIC Educational Resources Information Center

    Boissonneault, Chantal, Ed.

    Papers on language research include: "L'expression de l'opposition en Latin" ("The Expression of Opposition in Latin" (Claude Begin); "Le francais de l'Abitibi: characteristiques phonetiques et origine socio-geographique des locuteurs" ("The French of Abitibi: Phonetic Characteristics and Socio-Geographic Origin…

  5. Symbolic Non-Violence in the Work of Teachers in Alternative Education Settings

    ERIC Educational Resources Information Center

    Waters, Richard

    2017-01-01

    Patterns in analysis of research data on alternative education practices as well as on student and teacher experience in mainstream settings seem to support Pierre Bourdieu and Jean Claude Passeron's theory of symbolic violence. Data from teachers and students suggest that students from low socio-economic backgrounds often disengage from education…

  6. Modeling a Cryogenic HE3 Nuclear Gyro.

    DTIC Science & Technology

    1980-12-01

    Gryoscopes," J. of Applied Mechanics, Paper No. 57-A-72. Cohen - Tannoudji Claude , et al., Quantum Mechanics, (Vols. 1 and 2), John Wiley & Sons, New York...Classical treatments of the equation of motion of in a magnetic field can be found in Kittel [1976] or Cohen - Tannoudji (1977] . The same results are

  7. Quantum Mechanical Atomic Energy Operator.

    DTIC Science & Technology

    1984-12-01

    operator. 65 S. .. = . ?"L " -- ,V’ S ’ -. W W7 "b ’tp. i . -- ,’. Sr r ,- .- = . -. * -- r -. -.-- =, -. .. . .. Bibliography 1. Cohen - Tannoudji , Claude ...H(t)In(t)> = En(t)In(t)> (5.26) The solution follows the method of Cohen - Tannoudji (1:406-408), 420-423). The multipole Hamiltonian can be written as

  8. Auf De Suche Nach Der Guten Schule: In Search of a Great School

    ERIC Educational Resources Information Center

    Chirichello, Michael

    2009-01-01

    This module is the result of the author Michael Chirichello's visit to Luxembourg in 2008. He includes the contact information here for the Atert-Lycee Redange principal or director: Claude Boever, Directeur, email: directeur@alr.lu This publication aligns with the Interstate School Leaders Licensure Consortium (ISSLC) Standard 1: "An…

  9. Astronaut Jeffrey Hoffman on RMS during third of five HST EVAs

    NASA Technical Reports Server (NTRS)

    1993-01-01

    Astronaut Jeffrey A. Hoffman signals directions to Swiss Astronaut Claude Nicollier, as the latter controls the Remote Manipulator System (RMS) arm during the third of five space walks on the Hubble Space Telescope (HST) servicing mission. A portion of the Earth's surface can be seen directly behind him.

  10. Hearings Before the Select Committee on Nutrition and Human Needs of the United States Senate, Ninety-Second Congress, Second Session on Nutrition and Human Needs. Part 2--Nutritional Needs of Nation's Older Americans. Hearings Held Washington, D.C., June 14, 1972.

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. Senate Select Committee on Nutrition and Human Needs.

    This hearing before the Senate Select Committee on Nutrition and Human Needs began with opening statements by a number of senators. Following this, statements were made by a number of witnesses, including Hon. Claude Pepper, a U.S. Representative from the Eleventh District of the State of Florida; Dr. Jean Mayer, professor of nutrition, Harvard…

  11. It's a Wrap! A Study of Installations.

    ERIC Educational Resources Information Center

    Buck, Susan

    2002-01-01

    Describes an art project for junior and senior high school students called the wrapped chair project where students wrapped chairs using torn sheets in the style of artists, Christo Javacheff and Jeanne-Claude de-Guillebon. Explains that students created thumbnail sketches and drew their finished drawing in either charcoal or chalk. (CMK)

  12. Monet's Water Lilies

    ERIC Educational Resources Information Center

    Maroni, Michelle

    2006-01-01

    Students love the colors of Monet prints. The sunny yellows, misty blues, soft lavenders, and outrageous oranges. Using this as inspiration, Michelle Maroni wanted her students to discover new painting techniques and ways of planning a composition with more spontaneity. In this article, she describes how she introduced Claude Monet to her students…

  13. Harlem, History, and First-Year Composition: Reconstructing the Harlem of the 1930s through Multiple Research Methods

    ERIC Educational Resources Information Center

    Wilson, James

    2003-01-01

    Describing the Harlem Riot of 1935, black author and poet Claude McKay wrote, "On Tuesday the crowds went crazy like the remnants of a defeated, abandoned, and hungry army. Their rioting was the gesture of despair of a bewildered, baffled, and disillusioned people". By nearly all accounts, the riot marks the historical end of the Harlem…

  14. 33 CFR 117.458 - Inner Harbor Navigation Canal, New Orleans.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 1 2014-07-01 2014-07-01 false Inner Harbor Navigation Canal, New Orleans. 117.458 Section 117.458 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF... Harbor Navigation Canal, New Orleans. (a) The draws of the SR 46 (St. Claude Avenue) bridge, mile...

  15. 33 CFR 117.458 - Inner Harbor Navigation Canal, New Orleans.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 1 2011-07-01 2011-07-01 false Inner Harbor Navigation Canal, New Orleans. 117.458 Section 117.458 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF... Harbor Navigation Canal, New Orleans. (a) The draws of the SR 46 (St. Claude Avenue) bridge, mile...

  16. 33 CFR 117.458 - Inner Harbor Navigation Canal, New Orleans.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 1 2013-07-01 2013-07-01 false Inner Harbor Navigation Canal, New Orleans. 117.458 Section 117.458 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF... Harbor Navigation Canal, New Orleans. (a) The draws of the SR 46 (St. Claude Avenue) bridge, mile...

  17. 33 CFR 117.458 - Inner Harbor Navigation Canal, New Orleans.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Inner Harbor Navigation Canal, New Orleans. 117.458 Section 117.458 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF... Harbor Navigation Canal, New Orleans. (a) The draws of the SR 46 (St. Claude Avenue) bridge, mile...

  18. 33 CFR 117.458 - Inner Harbor Navigation Canal, New Orleans.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 1 2012-07-01 2012-07-01 false Inner Harbor Navigation Canal, New Orleans. 117.458 Section 117.458 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF... Harbor Navigation Canal, New Orleans. (a) The draws of the SR 46 (St. Claude Avenue) bridge, mile...

  19. Monet's Reflections

    ERIC Educational Resources Information Center

    Petrovich-Cheney, Laura

    2007-01-01

    From 1899 until his death in 1926, Claude Monet painted a series of watercolor landscapes of his water lily garden and Japanese bridge in Giverny, France. Monet eventually abandoned the banks entirely as subject matter and concentrated solely on the water. These paintings, particularly "The Water Lilies," show a surface in which the shimmering…

  20. Coding and Quantization in Communications and Microeconomics

    ERIC Educational Resources Information Center

    Xu, Yun

    2013-01-01

    Since information theory was developed by Claude E. Shannon, in addition to its primary role in communications and networking, it has broadened to find applications in many other areas of science and technology, such as microeconomics, statistics, and neuroscience. This thesis investigates the application of information theoretic viewpoints to two…

  1. Pathways and Participation in Vocational and Technical Education and Training.

    ERIC Educational Resources Information Center

    Organisation for Economic Cooperation and Development, Paris (France).

    This document presents 10 national reports on widely differing traditions regarding vocational and technical education and training (VOTEC) in Organisation for Economic Cooperation and Development countries. Chapter 1, "Synthesis of Country Reports" (Claude Pair), covers programs and pathways, quantitative trends in participation, and…

  2. Structural Reform in Higher Education Collective Bargaining. Proceedings of the Annual Conference of the National Center for the Study of Collective Bargaining in Higher Education and the Professions (12th, New York, New York, April 1984).

    ERIC Educational Resources Information Center

    Douglas, Joel M., Ed.

    Structural reform in higher education collective bargaining is examined in these conference proceedings, along with recent state bargaining legislation, and legal, union, and management views concerning sex discrimination in higher education. The 19 article topics and authors include: the problem of reshaping the fringe package (Claude Campbell);…

  3. Multiscale Problems in Materials Science: A Mathematical Approach to the Role of Uncertainty

    DTIC Science & Technology

    2010-10-01

    Claude Lebris Ecole Nationale des Ponts et Chaussées CERMICS 6-8, Avenue Blaise Pascal Marne la Vallée, France FR-77455 EOARD SPC 10-4002...Ecole Nationale des Ponts et Chaussées 6-8, Avenue Blaise Pascal Marne la Vallée FR-77455 France 8. PERFORMING ORGANIZATION REPORT NUMBER

  4. Judge Rules Plagiarism-Detection Tool Falls under "Fair Use"

    ERIC Educational Resources Information Center

    Young, Jeffrey R.

    2008-01-01

    Judge Claude M. Hilton, of the U.S. District Court in Alexandria, Virginia, in March found that scanning the student papers for the purpose of detecting plagiarism is a "highly transformative" use that falls under the fair-use provision of copyright law. He ruled that the company "makes no use of any work's particular expressive or creative…

  5. Identification of new phytoconstituents and antimicrobial activity in stem bark of Mangifera indica (L.).

    PubMed

    Singh, Ruchi; Singh, S K; Maharia, R S; Garg, A N

    2015-02-01

    Mangifera indica, commonly called mango or amra belonging to a family of Anacardiaceae, is an important medicinal plant widely used in a variety of Ayurvedic preparations. Extract of its bark, leaves, flowers and kernels are being extensively used for curing various chronic diseases. Mango wood is used in yagya as base fire through which medicated smoke is generated. Three new compounds have been isolated from methanolic and hexane extracts of stem bark: 1,2-benzenedicarboxylic acid, mono(2-ethylhexyl)ester and 9,12-tetradecadiene-1-ol-acetate from the hexane extract and 3-chloro-N-(2-phenylethyl) propanamide from the methanolic extract. These were first separated by thin layer chromatography and later in a silica gel column and identified by characteristic infrared bands corresponding to respective functional groups. The compounds were further confirmed on the basis of GC-MS fragmentation pattern after comparing the data with NIST mass spectral database. All three compounds exhibited antimicrobial activity due to triterpenoids and flavonoids. Elemental analyses by INAA show it to be enriched in essential nutrient elements such as Ca, Fe, K, Mn and Zn which all play an important role in enzymatic processes.

  6. Chandra Discovers the X-ray Signature of a Powerful Wind from a Galactic Microquasar

    NASA Astrophysics Data System (ADS)

    2000-11-01

    NASA's Chandra X-ray Observatory has detected, for the first time in X rays, a stellar fingerprint known as a P Cygni profile--the distinctive spectral signature of a powerful wind produced by an object in space. The discovery reveals a 4.5-million-mile-per-hour wind coming from a highly compact pair of stars in our galaxy, report researchers from Penn State and the Massachusetts Institute of Technology in a paper they will present on 8 November 2000 during a meeting of the High-Energy Astrophysics Division of the American Astronomical Society in Honolulu, Hawaii. The paper also has been accepted for publication in The Astrophysical Journal Letters. "To our knowledge, these are the first P Cygni profiles reported in X rays," say researchers Niel Brandt, assistant professor of astronomy and astrophysics at Penn State, and Norbert S. Schulz, research scientist at the Massachusetts Institute of Technology. The team made the discovery during their first observation of a binary-star system with the Chandra X-ray Observatory, which was launched into space in July 1999. The system, known as Circinus X-1, is located about 20,000 light years from Earth in the constellation Circinus near the Southern Cross. It contains a super-dense neutron star in orbit around a normal fusion-burning star like our Sun. Although Circinus X-1 was discovered in 1971, many properties of this system remain mysterious because Circinus X-1 lies in the galactic plane where obscuring dust and gas have blocked its effective study in many wavelengths. The P Cygni spectral profile, previously detected primarily at ultraviolet and optical wavelengths but never before in X rays, is the textbook tool astronomers rely on for probing stellar winds. The profile looks like the outline of a roller coaster, with one really big hill and valley in the middle, on a data plot with velocity on one axis and the flow rate of photons per second on the other. It is named after the famous star P Cygni, in which such

  7. Convergence Rate in Adaptive Radar

    DTIC Science & Technology

    1976-02-01

    D.R ?UMallettiS Technolorg Service Corporation < Fan85. oppr l echmology Service Corporation 2811 WILSHIRE BOULEVARD SANTA MONICA, CALIFORNIA 90403...PRINT 510 GiO TO (800810P); 13 80 Yjl(IR)=SSG#AV8 Ytl -(IR)=S$G+AVL Gu 10 300 8t y21(IR)CSSG+AVS Y22(IR):SSGtAVL GO TO0300- 82 Y31(IR)zSSGIAVS v32( IR...Research Corporation Merrill Lane Uaiversity eighas Syracuse, New, York 13210 * Attn: M!r. Sidney AplebauLa Dr. Norbert N’,oj 16 Circle Drive ’loorestown

  8. Quantum mechanical coherence, resonance, and mind

    SciTech Connect

    Stapp, H.P.

    1995-03-26

    Norbert Wiener and J.B.S. Haldane suggested during the early thirties that the profound changes in our conception of matter entailed by quantum theory opens the way for our thoughts, and other experiential or mind-like qualities, to play a role in nature that is causally interactive and effective, rather than purely epiphenomenal, as required by classical mechanics. The mathematical basis of this suggestion is described here, and it is then shown how, by giving mind this efficacious role in natural process, the classical character of our perceptions of the quantum universe can be seen to be a consequence of evolutionary pressures for the survival of the species.

  9. UCAC4 Nearby Star Survey: A Search for Our Stellar Neighbors

    DTIC Science & Technology

    2014-12-01

    UCAC4 NEARBY STAR SURVEY: A SEARCH FOR OUR STELLAR NEIGHBORS Charlie T. Finch1, Norbert Zacharias1, John P. Subasavage2, Todd J. Henry3, and Adric R...Catalog (UCAC4) in combination with photometry from the AAVSO Photometric All-Sky Survey and Two Micron All-Sky Survey to identify stars within 25 pc of...the Sun. A sample of nearby stars with accurate trigonometric parallaxes from the Research Consortium On Nearby Stars is used to generate a set of 16

  10. The story of the body and the story of the person: towards an ethics of representing human bodies and body-parts.

    PubMed

    Barilan, Y Michael

    2005-01-01

    Western culture has a few traditions of representing the human body - among them mortuary art (gisants), the freak show, the culture of the relics, renaissance art and pre-modern and modern anatomy. A historical analysis in the spirit of Norbert Elias is offered with regard to body - person relationship in anatomy. Modern anatomy is characterized by separating the story of the person from the story of the body, a strategy that is incompatible with the bio-psycho-social paradigm of clinical medicine. The paper discusses different aspects of the above traditions and how they might bear on this conflict and on contemporary bioethics and bedside practice.

  11. [Pertinence of the Elias approach in history of medicine].

    PubMed

    Wenger, Alexandre

    2003-01-01

    Norbert Elias has notably influenced the historiography of the Early Modern Period since the 1970s. In the course of the borrowing of his concepts by different disciplines, the uniqueness of these concepts was nevertheless altered. This article aims to show that Elias' 'Sociology of configurations' proposed an original point of view on Longue Durée in history. It thus suggests: 1) to re-evaluate the historical dimension of Elias' sociology; 2) to question eventual contributions to present-day research to the history of medicine and health.

  12. A-Train Data Depot (ATDD)

    NASA Technical Reports Server (NTRS)

    Smith, Peter M.; Kempler, Steven; Leptoukh, Gregory; Savtchenko, Andrey; Kummerer, Robert; Gopolan, Arun

    2008-01-01

    ATDD is a web based tool which provides collocated data and display products for a number of A-train instruments Cloudsat, Calipso, OMI, AIRS, MODIS, MLS, POLDER-3, and ECWMF model data. Products provided include Clouds, Aerosols, Water Vapor, Temperatures and trace gases. All input data is online and in HDF4, HDF5 format. Display products include curtain images, horizontal strips, line plot overlays, and GE kmz files. Sample products are shown for two type of events. Hurricane event, Norbert, Oct 8, 2008 and a dust storm event over the Arabian Sea, Nov 13-14, 2008.

  13. [The relationship between Bergson's philosophy and medicine].

    PubMed

    Kulczycki, J

    1994-01-01

    The relationship between Bergson's philosophy and medicine follows an outline of theoretical situation in philosophy in the second half of 19c. The former relationship is evident in Bergson's mind-body considerations and thoughts concerning philosophical importance of Claude Bernard's works and are of bilateral nature. Bergson criticized lokalization theory and psychophysical paralelism on the ground of the contemporary neurology and psychiatry. Conversely his ideas, particularly those concerning the nature of conscioiusness and aphasia were reflected in both psychopathology and neurology. Bergson perceives the philosophical importance of Claude Bernard primarily in his theoretical experimental bases for research in medicine and biology. The paper closes considering the importance of various conceptions of personality (including Bergson's) in philosophy of medicine and medical practice.

  14. [52th Commemoration of French Journal of Plastic Aesthetic Surgery (1956-2007). Fifty-four years of editorial; five Editors-in-chief].

    PubMed

    Cariou, J-L

    2007-08-01

    The french Society of Plastic Reconstructive and Aesthetic Surgery (SOF.CPRE) is born December 3th 1952. Initially without "aesthetic", this "key-word" is agreed in 1983 and the symbols are advanced since: SFCPR, SFCPRE, SOF.CPRE. Its official organ, formerly included in Annales de chirurgie (1954-1955), become Annales de chirurgie plastique in 1956, Annales de chirurgie plastique et esthétique in 1983 and finally Annales de chirurgie plastique esthétique (ACPE) in 1992. Since the origin, five Editors-in-chief succeded: Claude Dufourmentel, Raymond Vilain, Jean-Pierre Lalardrie, Claude Lê-Quang, Jean-Luc Cariou. Four of them are alive, Raymond Vilain is dead. The author relate here the natural story of these five editors who had all a triple route: personnal, surgical and editorial.

  15. Comparison between reverse Brayton and Kapitza based LNG boil-off gas reliquefaction system using exergy analysis

    NASA Astrophysics Data System (ADS)

    Kochunni, Sarun Kumar; Chowdhury, Kanchan

    2017-02-01

    LNG boil-off gas (BOG) reliquefaction systems in LNG carrier ships uses refrigeration devices which are based on reverse Brayton, Claude, Kapitza (modified Claude) or Cascade cycles. Some of these refrigeration devices use nitrogen as the refrigerants and hence nitrogen storage vessels or nitrogen generators needs to be installed in LNG carrier ships which consume space and add weight to the carrier. In the present work, a new configuration based on Kapitza liquefaction cycle which uses BOG itself as working fluid is proposed and has been compared with Reverse Brayton Cycle (RBC) on sizes of heat exchangers and compressor operating parameters. Exergy analysis is done after simulating at steady state with Aspen Hysys 8.6® and the comparison between RBC and Kapitza may help designers to choose reliquefaction system with appropriate process parameters and sizes of equipment. With comparable exergetic efficiency as that of an RBC, a Kaptiza system needs only BOG compressor without any need of nitrogen gas.

  16. [The Pluvinet, chemists and grocers, during the french Revolution and the Empire].

    PubMed

    Flahaut, Jean

    2003-01-01

    Between 1750 and 1813, the ancient archives described two Pluvinet: Jean-Claude and Jean-Charles (or Jean-Baptiste-Charles). They were chemists and grocers; they had various activities, with Lavoisier, with Cadet de Gassicourt, at the Council of the City of Paris, etc. But frequent confusions exist between the two first names, and it seems possible that they concern only one man, who changed his first name according to the events.

  17. West Europe Report. No. 2178.

    DTIC Science & Technology

    1983-07-22

    Jersild; BERLINGSKE TIDENDE, 23 Jun 83) 25 FRANCE PS Factions Split on Protectionism, Devaluation ( Jean -Claude Hazera; LE NOUVEL ECONOMISTE, 13 Jun...of Belgium, by reporters Charles Bricman, Benoit Califice, and Jacques Dujardin, in Liege, date and occasion not specified: "Robert the Rebel...the march on Brussels, Jacques Yerna had contacted Piette. We found the answer the next day...in the press. It was "No!" In fact, it is not very

  18. Organization of the Integrated Photonics Topical Meeting Held in Victoria, British Columbia on 30 March-1 April 1998. Technical Digest Series. Volume 4. Postconference Edition

    DTIC Science & Technology

    2007-11-02

    four- wave mixing characteristics of X./4-sn,fted DFB lasers, Jacques W.D. Chi, Jean Le Bihan, Ecole Nationale d’Inginieurs de Brest, France; K... Jacques W. D. CHI, K. Alan SHORE* and Jean LE BIHAN Ecole Nationale d’Ingenieurs de Brest, Laboratoire RESO Technopöle Brest-Iroise, C.P. 15,29608 BREST...Texas Instruments, USA Kunishige Oe, NTT Opto-electronics Laboratories, Japan Claude Rolland, Nortel Technology, Canada Jean -Francois Vinchant

  19. Development of a Higher-Order Upwind Algorithm for Discontinuous Compressible Flow

    DTIC Science & Technology

    2005-03-01

    circumstance. They were originally proposed by Leonhard Euler in the mid 1750’s, and later refined by Claude Louis Marie Henri Navier in the early 1820’s...the com- pressible Euler equations that include compact differencing cannot be applied to problems involving discontinuities (such as shock or contact...Riemann solver was investigated. This method was incorporated into a one-dimensional numerical simulation of the compressible Euler equations, and

  20. The China-Africa Connection: Implications for United States Foreign Policy

    DTIC Science & Technology

    1992-06-01

    CONNECTION: IMPLICATIONS FOR UNITED STATES FOREIGN POLICY Bernadette M. Semple June 1992 Thesis Advisor: Claude Buss Approved for public release; distribution...ELEMENT NO. NO.N. ACCESSWONR U NO. 11. 11 LIE (Incudie Secunly Glassiamlon) The China-Africa Connection: Implications for United States Foreign Policy ...June, 1992 d 130 1& ,UPPLMEINAY NIAIION The views expressed in this paper are those of the author and do not reflect the official policy or position

  1. Survivable Loosely Coupled Architectures

    DTIC Science & Technology

    2003-03-01

    Verlag Lecture Notes in Computer Science, pages 291–303, Pune, India, September 2000. [6] Saddek Bensalem, Marius Bozga, Jean - Claude Fernandez, Lucian...IEEE Computer Society. [5] John Rushby. An overview of formal verification for the time-triggered architecture. In Werner Damm and Ernst-Rüdiger...Agathe Merceron. Parametric verification of a group membership algo- rithm. In Werner Damm and Ernst-Rüdiger Olderog, editors, Formal Techniques in Real

  2. Summary of Technical Operations, 1991

    DTIC Science & Technology

    1992-01-01

    34Can We Rely on Fault Tolerant Sys- tems?," and Dr. Jean - Claude Laprie, a director at CNRS-LAAS, Toulouse, France, 14 1991 Summary of Technical...Redesign ( DAMMS -R). The domain model will be used in both the Operational Movement Program and Highway Operations Team subsystems of DAMMS -R. Project...SEI will use the model as a basis for designing reusable software packages to be used initially for DAMMS -R and subsequently for ATCCS battlefield

  3. The United Nations Security Council Veto in the New World Order

    DTIC Science & Technology

    1992-04-01

    Shoffner, SASO to FMSO: Assessing the New World Order, Military Review, Dec. 1991, at preface. 10. Natsec Strategy, supra note 1, at 3. . 11. See Cass R... Sunstein , Constitutionalism and Secession, 58 U. Chi. L. Rev. 633, 640 (1991) [hereinafter Sunstein ]. 12. See Claude, supra note 7, at 253 (on the need...File [hereinafter Genscher on Yugoslavia]. 52. See Sunstein , supra note 11, at 654. . 53. Steven L. Burg, Nationalism and Democratization in

  4. A Course Connecting Astronomy to Art, History, and Literature

    NASA Astrophysics Data System (ADS)

    Olson, Don

    2015-10-01

    For the past 20 years the author has taught an Honors College course combining astronomy and the humanities. The purpose of this note is to give examples of methods that can be adapted to classroom use for topics including night sky paintings by Vincent van Gogh, Edvard Munch, and Claude Monet, historical events influenced by astronomical factors, and literary references to the sky by authors including Chaucer, Shakespeare, and Walt Whitman.

  5. Latency-Information Theory: The Mathematical-Physical Theory of Communication-Observation

    DTIC Science & Technology

    2010-01-01

    Werner Heisenberg of quantum mechanics; 3) the source-entropy and channel-capacity lossless performance bounds of Claude Shannon that guide...through noisy intel-space channels, and where the physical time-dislocations of intel-space exhibit a passing of time Heisenberg information...life-space sensor, and where the physical time- dislocations of life-space exhibit a passing of time Heisenberg information-uncertainty; and 4

  6. ESA MS Nicollier, assisted by technicians, dons EMU upper torso in JSC's WETF

    NASA Technical Reports Server (NTRS)

    1987-01-01

    European Space Agency (ESA) Mission Specialist (MS) Claude Nicollier, wearing liquid cooling and ventilation garment (LCVG) and extravehicular mobility unit (EMU) lower torso, crouches under EMU upper torso. Technicians extend the sleeves enabling Nicollier to insert his arms into the armholes. Once fully suited in the EMU, Nicollier will be lowered via the platform into JSC's Weightless Environment Training Facility (WETF) Bldg 29 pool for an underwater extravehicular activity (EVA) simulation and familiarization session.

  7. STS-75 Payload Specialist Umberto Guidoni suits up

    NASA Technical Reports Server (NTRS)

    1996-01-01

    STS-75 Payload Specialist Umberto Guidoni (right) chats with fellow crew member Mission Specialist Claude Nicollier during suitup activities in the Operations and Checkout Building. Guidoni represents the Italian Space Agency and is one of three international crew members assigned to STS-75. He and six fellow crew members will depart shortly for Launch Pad 39B, where the Space Shuttle Columbia awaits liftoff during a two-and-a-half- hour launch window opening at 3:18 p.m. EST.

  8. Survey of Neural Net Paradigms for Specification of Discrete Networks.

    DTIC Science & Technology

    1988-01-31

    appendix. 23 References 1. Cambier, J.L., Barth , S., Reid, W.J., Barrett,S., "Advanced Pattern Recognition", F30602-80-C-0319. ADA 132 339 2. Elman, J.L...Nov. 1985. ., .U U - - A 1 Bibliography Berge, Claude, "Principles of Combinatorics", Academic Press, 1971 Fischer, Roland , "Deconstructing Reality... Roland W., "Cognitive Strategies in Stochastic Thinking", D. Reidel, 1982(?) Searle, John, "Expression and Meaning", Cambridge U. Press, 1979 Talmy

  9. Latin America Report No. 2739

    DTIC Science & Technology

    2007-11-02

    being hot never has abrupt thermometer changes upward or downward as happens with the cold nights in the desert. For Gil Castellanos the climate and... coffee -producing areas will reduce the volume of the harvest of this commodity and 1984—a high year in the biennial cycle—will paradoxically have a...course. Sylvio Claude himself shows no signs of life, for reasons of security according to some sources. No one knows whether he is brewing something

  10. [The ethics of animal experimentation].

    PubMed

    Goffi, Jean-Yves

    2013-01-01

    The paper starts with a short definition of animal experimentation, then three main approaches to the practice are considered: unconditional approval (as advocated by Claude Bernard), conditional and restricted approval (as advocated by Peter Singer) and strict prohibition (as advocated by Tom Regan and Gary Francione). It is argued that what is actually approved or condemned in animal experimentation is the value of the scientific enterprise.

  11. A Research Design for Archaeological Investigations and Architectural Evaluations within the Proposed Upper Site, New Lock and Connecting Channels, Inner Harbor Navigation Canal, New Orleans, Louisiana

    DTIC Science & Technology

    1991-02-27

    balance of trade at this date. Planters owed over three million livres for previous shipments of slaves and supplies. By that time, structures within New...Delavigine (Lots 7 to 18). The frame buildings lying within the projected passage of Jourdan Avenue between Maurais and St. Claude, were purchased by...the top lends additional rigidity. It was also justified at South Halsted Street to provide machinists with quick passage from the top of one tower

  12. The Gates, 1979-2005

    ERIC Educational Resources Information Center

    School Arts: The Art Education Magazine for Teachers, 2005

    2005-01-01

    One art critic called it pure Despite the mixed reviews of Christo and Jeanne-Claude's temporary art installation in New York's Central Park, the public reaction to The Gates was largely positive.The Gates consisted of 7,500 orange PVC frames straddling the park's walkways that varied in widths from 5 1/2 feet to 18 feet. Eight-foot-long ripstop…

  13. Army Communicator. Volume 28, Number 4, Winter 2003

    DTIC Science & Technology

    2003-01-01

    and control, communications, logistics, target acquisition and intelligence. Initially, Stryker brigades 1 through 4 will each have 12 M -198 155mm...acquisition award presented to Army organizations for 2002 - at the Acquisition Senior Leaders’ Conference in Seattle, Wash. on Aug. 14, 2003. Claude M ...the average soldier.” Other reservists from the 276th who assisted were SSG Eduardo Lopez, SPC Samuel Morales, and PFC Elvis Torres. SPC Toby

  14. The Operational Level of War

    DTIC Science & Technology

    1985-12-01

    Ramsay III, Dr. William G. Robertson, Major Claude R. Sasso, and Lieutenant Colonel Gary H. Wade. We owe special thanks to a few individuals who...initially assembled this bibliography in response to a requirement by Brigadier General William A. Stofft, then a colonel and director of CSI...and World War I. This battle analysis is accomplished largely at the operational level and is beneficial to the reader. Balck, Wilhelm ( William

  15. Nonlinear Optical Studies of Resonant Systems

    DTIC Science & Technology

    1989-06-14

    1986), Appl. Phys. Lett. 49, 1275 Cohen , E., and M.D. Sturge (1982), Phys. Rev. B 25, 3828. Cohen - Tannoudji , Claude (1977), in Frontiers in Laser...evaluation of this term including the use of reservoir theory in the density matrix ( Cohen - Tannoudji , 1977). For many cases of interest, the...review of relaxation, see Cohen -Tan -iAi, 1977). The velocity term on the left hand side describes motion of tb ’enter of mass for gas phase systems

  16. Naval War College Review. Volume 60, Number 1, Winter 2007

    DTIC Science & Technology

    2007-01-01

    nuclear diffusion network.”) 22. See John S. Hammond et al ., Smart Choices (Boston: Harvard Business School Press, 1999), p. 209. Cognitive errors may...caltechc/clibrary/CD%20056/ts056058.pdf. 115. , , [Lu Jiaben, Wang Shen- glong, Liu Wen, et al .], “‘ ’ ” [Evaluation of Health Protective Effects of...Inis L. Claude, Jr. Norman Friedman Colin Gray Capt. Wayne P. Hughes, Jr., USN (Ret.) Paul M. Kennedy James R. Kurth Robert J . Murray George H

  17. Investigations of Human Question Answering

    DTIC Science & Technology

    1990-02-01

    Aiello, & Miller, 1975; Graesser & Black, 1985; Graesser & Golding, 1988; Norman, 1973; Norman & Rumelhart, 1975; Piaget , 1952; Shanon, 1983; Trabasso...Rumelhart, D. E. (1975). Explorations in cognition. San Francisco: Freeman. Piaget , J. (1952). The origins of intelligence in children. New York...California 5825 Callaghan, Suite 225 Santa Barbara, CA 93106 San Antonio, TX 78228 Dr. Ralph Dusek Dr. Jean -Claude Falmagne V-P Human Factors Irvine

  18. Southeast Asia Report.

    DTIC Science & Technology

    1984-03-22

    Caledonia are increasing. Two weeks ago, the Melanesian tribe of Poinda, 300 kilometers from Noumea, called upon the Devillers family to leave its...land reform. Jean-Claude Devillers had won an extension of the deadline for leaving his property; however, the tribes in that area, con- vinced that...similar invi- tation had been given to the Tasmanian state minister and his officials. The Tasmanian visit will try to sort out problems of competition

  19. Solar Sea Power Plants (SSPP): A critical review and survey

    NASA Technical Reports Server (NTRS)

    Strauss, A. M.

    1974-01-01

    An overview of technical and economic matters relating to the eventual success or failure of the SSPP concept is presented, with emphasis on the pollution and energy problems which the SSPP would serve to eliminate. Factors discussed include cost, mariculture possibilities, siting, legal limitations, design materials, mooring and anchoring, and the human element involved. Several alternative power systems are considered for incorporation into SSPP design, such as Nitinol power, Claude cycle, and closed cycle engine systems.

  20. Army Logistician. Volume 39, Issue 2, March-April 2007

    DTIC Science & Technology

    2007-04-01

    Members The Honorable Claude M . Bolton, Jr. Assistant Secretary of the Army Acquisition, Logistics, and Technology Lieutenant General Ann E. Dunwoody...Shelley A. Richardson Commandant Barbara G. Mroczkowski Assistant Commandant STAFF Robert D . Paulus, Editor Janice L. Simmons, Assistant Editor April...movement control functions of the 27th Movement Control Bat- talion under the supervision of the 3d COSCOM sup- port operations staff to achieve a

  1. Portable Diode Pumped Femtosecond Lasers

    DTIC Science & Technology

    2007-03-01

    interest to the USAF is the possible development of enhanced laser gyroscopes. There are still a number of mechanical inertial navigation units being used...aerial systems such as unmanned aerial reconnaissance vehicles could benefit from inertial systems built around smaller and faster pulse rates...Related To Fast Ignitor In Inertial Confinement Fusion, 17, October 1998. 14. Jean-Claude Diels, Wolfgang Rudolph. Ultrashort Laser Pulse Phenomena: Fun

  2. Transverse and Quantum Effects in Light Control by Light; (A) Parallel Beams: Pump Dynamics for Three Level Superfluorescence; and (B) Counterflow Beams: An Algorithm for Transverse, Full Transient Effects in Optical Bi-Stability in a Fabryperot Cavity.

    DTIC Science & Technology

    1983-01-01

    International Division) - Pierre Cadieux (system routine for data bases) - Michel Cormier (user interface for data base) - Yve Claude (pagination of...like a Foucault pendulum. (See Fig. 6b). The SF process is a unique macroscopic manifestation of quantum fluctuations, even though they are proportional...otherwise. (b) No level degeneracy, T2 = T2 =, KL = 0. (c) T2 = m. (d) T2 = . Ce) KL = 0. (f) KL 5. (g) No level degeneracy. Fig. 6b. Foucault pendulum co

  3. NATO Advanced Research Workshop: Vortex Flows and Related Numerical Methods (Ecoulements Tourbillonnaires et Methodes Numeriques) Held in Grenoble-St. Pierre de Chartreuse, France on June 15-19, 1992. List of Participants (Liste des Participants), Book of Abstracts (Resumes), Instructions for Submission to the Proceedings (Format pour les Actes).

    DTIC Science & Technology

    1992-06-01

    55 e-mail: buttke@math.ias.edu e-mail: baras@imag.fr Claude Basdevant Emanuele Caglioti LMD Dipatimento Matematica Ecole Normale Superieure Universita...Dipartimento Matematica CALTECH Universita ’La Sapienza’ Pasadena, CA 91125, USA Piazzale Aldo Moro, 2 Tel.: (818) 356 44 62 00185 Roma, ITALIE Fax: (818...Vortices and Localizgtion in Euler Flows. Carlo Marchiom Dipainento di Matematica , Universitk "La Sapienza", Piazzale A.Moro 2, 00185 ROMA ,haly It is

  4. ESA MS Nicollier extends mockup tetherline prior to JSC WETF simulation

    NASA Technical Reports Server (NTRS)

    1987-01-01

    European Space Agency (ESA) Mission Specialist (MS) Claude Nicollier, turning a crank, extends a tetherline from a reel mounted on a mockup of the forward payload bay (PLB) bulkhead. Nicollier familiarizes himself with the operation of the safety tether system prior to donning an extravehicular mobility unit (EMU) and participating in an underwater extravehicular activity (EVA) simu- lation in JSC's Weightless Environment Training Facility (WETF) Bldg 29 pool.

  5. Plant anesthesia supports similarities between animals and plants

    PubMed Central

    Grémiaux, Alexandre; Yokawa, Ken; Mancuso, Stefano; Baluška, František

    2014-01-01

    The French scientist Claude Bernard (1813–1878) is famous for his discoveries in physiology and for introducing rigorous experimental methods to medicine and biology. One of his major technical innovations was the use of chemicals in order to disrupt normal physiological function to test hypotheses. But less known is his conviction that the physiological functions of all living organisms rely on the same underlying principles. He hypothesized that similarly to animals, plants are also able to sense changes in their environment. He called this ability “sensitivity.” In order to test his ideas, he performed anesthesia on plants and the results of these experiments were presented in 1878 in “Leçonssur les phénomènes de la vie communs aux animaux et aux végétaux.”1 The phenomena described by Claude Bernard more than a century ago are not fully understood yet. Here, we present a short overview of anesthetic effects in animals and we discuss how anesthesia affects plant movements, seed germination, and photosynthesis. Surprisingly, these phenomena may have ecological relevance, since stressed plants generate anesthetics such as ethylene and ether. Finally, we discuss Claude Bernard's interpretations and conclusions in the perspective of modern plant sciences. PMID:24476640

  6. Isooctane transport and remediation in soil using lysimeters

    NASA Astrophysics Data System (ADS)

    Colarieti, M. L.; Toscano, G.; Greco, G.

    2009-04-01

    The AMRA lysimeter station (near Piana di Monte Verna, Caserta, Italy) consists of eight weighable monolithic groundwater lysimeters fully equipped with sensors to provide continuous monitoring of temperature, humidity, water tension and weight, as well as ports for soil, liquid and gas sampling. An air-injection system allows to perform venting or sparging actions into contaminated soils and groundwater. A meteo station provides the indispensable data to evaluate the interactions between lysimeters and the meteorological phenomena on site. A preliminary experiment was performed last year to investigate the reactive transport of a NAPL-type contaminant under passive transport conditions and during an air-venting remediation action. 2,2,4-trimethylpentane (isooctane) was chosen as a representative contaminant from gasoline fuels. Four lysimeters containing undisturbed soil extracted from a former industrial site were used. Surface vegetation was cut to avoid leaves interference during contamination phase. Two lysimeters were contaminated by distributing a fixed amount of isooctane onto the soil surface, while two more lysimeters were left uncontaminated for reference. Only for one of the two contaminated lysimeters air was vented through a port at 150 cm depth. Air injection started 30 min after the contamination, lasted all the experiment time, and was applied also to one of the reference lysimeters. Gas samples were drawn periodically at different depths of the two contaminated lysimeters and analysed for isooctane content. Evolution of isooctane concentration profiles was different in the two contaminated lysimeters. In case of air-venting the contaminant maximum concentration was lower and the maximum depth reached by the contaminant was reduced. The time needed for a complete remediation action was compared with theoretical estimates computed according to normative procedures.

  7. First Streptococcus pyogenes signature-tagged mutagenesis screen identifies novel virulence determinants.

    PubMed

    Kizy, Anne E; Neely, Melody N

    2009-05-01

    The virulence of bacterial pathogens is a complex process that requires the dynamic expression of many genes for the pathogens to invade and circumvent host defenses, as well as to proliferate in vivo. In this study, we employed a large-scale screen, signature-tagged mutagenesis (STM), to identify Streptococcus pyogenes virulence genes important for pathogenesis within the host. Approximately 1,200 STM mutants were created and screened using the zebrafish infectious disease model. The transposon insertion site was identified for 29 of the 150 mutants that were considered attenuated for virulence. Previously reported streptococcal virulence genes, such as mga, hasA, amrA, smeZ, and two genes in the sil locus, were identified, confirming the utility of the model for revealing genes important for virulence. Multiple genes not previously implicated in virulence were also identified, including genes encoding putative transporters, hypothetical cytosolic proteins, and macrolide efflux pumps. The STM mutant strains display various levels of attenuation, and multiple separate insertions were identified in either the same gene or the same locus, suggesting that these factors are important for this type of acute, invasive infection. We further examined two such genes, silB and silC of a putative quorum-sensing regulon, and determined that they are significant virulence factors in our model of necrotizing fasciitis. sil locus promoter expression was examined under various in vitro conditions, as well as in zebrafish tissues, and was found to be differentially induced. This study was a unique investigation of S. pyogenes factors required for successful invasive infection.

  8. Isolation and characterization of a β-propeller gene containing phosphobacterium Bacillus subtilis strain KPS-11 for growth promotion of potato (Solanum tuberosum L.)

    PubMed Central

    Hanif, Muhammad Kashif; Hameed, Sohail; Imran, Asma; Naqqash, Tahir; Shahid, Muhammad; Van Elsas, Jan D.

    2015-01-01

    Phosphate-solubilizing and phytate-mineralizing bacteria collectively termed as phosphobacteria provide a sustainable approach for managing P-deficiency in agricultural soils by supplying inexpensive phosphate to plants. A phosphobacterium Bacillus subtilis strain KPS-11 (Genbank accession no. KP006655) was isolated from potato (Solanum tuberosum L.) rhizosphere and characterized for potato plant growth promoting potential. The strain utilized both Ca-phosphate and Na-phytate in vitro and produced 6.48 μg mL-1 indole-3-acetic acid in tryptophan supplemented medium. P-solubilization after 240 h was 66.4 μg mL-1 alongwith the production of 19.3 μg mL-1 gluconic acid and 5.3 μg mL-1 malic acid. The extracellular phytase activity was higher (4.3 × 10-10 kat mg-1 protein) than the cell-associated phytase activity (1.6 × 10-10 kat mg-1 protein). B. subtilis strain KPS-11 utilized 40 carbon sources and showed resistance against 20 chemicals in GENIII micro-plate system demonstrating its metabolic potential. Phytase-encoding gene β-propeller (BPP) showed 92% amino acid similarity to BPP from B. subtilis (accession no.WP_014114128.1) and 83% structural similarity to BPP from B. subtilis (accession no 3AMR_A). Potato inoculation with B. subtilis strain KPS-11 increased the root/shoot length and root/shoot weight of potato as compared to non-inoculated control plants. Moreover, rifampicin-resistant derivative of KPS-11 were able to survive in the rhizosphere and on the roots of potato up to 60 days showing its colonization potential. The study indicates that B. subtilis strain KPS-11 can be a potential candidate for development of potato inoculum in P-deficient soils. PMID:26106383

  9. Chandra Observatory Uncovers Hot Stars In The Making

    NASA Astrophysics Data System (ADS)

    2000-11-01

    their type," said Norbert S. Schulz, MIT research scientist at the Chandra X-ray Center, who leads the Orion Project. "And by extreme, we mean temperatures which are in some cases well above 60 million degrees." The hottest massive star known so far has been around 25 million degrees. The great Orion Nebula harbors the Orion Nebula Cluster (ONC), a loose association of around 2,000 mostly very young stars of a wide range of mass confined within a radius of less than 10 light years. The Orion Trapezium Cluster is a younger subgroup of stars at the core of the ONC confined within a radius of about 1.5 light years. Its median age is around 300,000 years. The constant bright light of the Trapezium and its surrounding stars at the heart of the Orion nebula (M42) are visible to the naked eye on clear nights. In X-rays, these young stars are constantly active and changing in brightness, sometimes within half a day, sometimes over weeks. "Never before Chandra have we seen images of stellar activity with such brilliance," said Joel Kastner, professor at the Chester F. Carlson Center for Imaging Science at the Rochester Institute of Technology. "Here the combination of very high angular resolution, with high quality spectra that Chandra offers, clearly pays off." The observation was performed using the High Energy Transmission Grating Spectrometer (HETGS) and the X-ray spectra were recorded with the spectroscopic array of the Advanced CCD Imaging Spectrometer (ACIS). The ACIS detector is a sophisticated version of the CCD detectors commonly used in video cameras or digital cameras. The orion stars are so bright in X-rays that they easily saturate the ccds. Here the team used the gratings as a blocking filter. Orion Trapezium - X-ray & Optical JPEG, TIFF, PS X-ray contours of the Chandra observation overlaid onto the optical Hubble image (courtesy of J. Bally, CASA Colorado). The field of view is 30"x30". Besides the bright main Trapezium stars, which were found to be extremely

  10. NOSS science working group

    NASA Astrophysics Data System (ADS)

    The members of the NOSS Science Working Group are John Apel, Pacific Marine Environmental Laboratories/NOAA; Tim Barnett, Scripps Institution of Oceanography; Francis Bretherton (chairman), National Center for Atmospheric Research; Otis Brown, University of Miami; Joost Businger, University of Washington; Garrett Campbell, NCAR; Mark Cane, Massachusetts Institute of Technology; Robert Edwards, National Marine Fisheries Service/NOAA; James Mueller, Naval Postgraduate School; Peter Niiler, Oregon State University; James J. O'Brien, Florida State University; Norman Phillips, National Meteorological Center/NOAA; Owen Phillips, The Johns Hopkins University; Stephen Piacsek, NSTL Station, NORDA; Trevor Platt, Bedford Institute of Oceanography; Stephen Pond, University of British Columbia; Stanley Ruttenberg (executive secretary), NCAR; William Schmitz, Woods Hole Oceanographic Institution; Jerry Schubel, State University of New York; Robert Stewart, Scripps; Norbert Untersteiner, NOAA; and Alan Weinstein, Naval Environmental Prediction Research Facility.

  11. Philosophical Approaches towards Sciences of Life in Early Cybernetics

    NASA Astrophysics Data System (ADS)

    Montagnini, Leone

    2008-07-01

    The article focuses on the different conceptual and philosophical approaches towards the sciences of life operating in the backstage of Early Cybernetics. After a short reconstruction of the main steps characterizing the origins of Cybernetics, from 1940 until 1948, the paper examines the complementary conceptual views between Norbert Wiener and John von Neumann, as a "fuzzy thinking" versus a "logical thinking", and the marked difference between the "methodological individualism" shared by both of them versus the "methodological collectivism" of most of the numerous scientists of life and society attending the Macy Conferences on Cybernetics. The main thesis sustained here is that these different approaches, quite invisible to the participants, were different, maybe even opposite, but they could provoke clashes, as well as cooperate in a synergic way.

  12. Social scientists in public health: a fuzzy approach.

    PubMed

    do Nascimento, Juliana Luporini; Stephan, Celso; Nunes, Everardo Duarte

    2015-05-01

    This study aims to describe and analyze the presence of social scientists, anthropologists, sociologists and political scientists in the field of public health. A survey by the Lattes Curriculum and sites of Medical Colleges, Institutes of Health Research Collective, seeking professionals who work in healthcare and have done some stage of their training in the areas of social sciences. In confluence with Norbert Elias' concepts of social networks and configuration of interdependence it was used fuzzy logic, and the tool free statistical software R version 2.12.0 which enabled a graphic representation of social scientists interdependence in the field of social sciences-health-social sciences. A total of 238 professionals were ready in 6 distinct clusters according to the distance or closer of each professional in relation to public health and social sciences. The work was shown with great analytical and graphical representation possibilities for social sciences of health, in using this innovative quantitative methodology.

  13. ON THE PRAGMATICS OF SOCIAL THEORY: THE CASE OF ELIAS'S "ON THE PROCESS OF CIVILIZATION".

    PubMed

    DA Silva, Filipe Carreira; Bucholc, Marta

    2016-09-01

    This paper proposes a new approach to the study of sociological classics. This approach is pragmatic in character. It draws upon the social pragmatism of G. H. Mead and the sociology of texts of D. F. McKenzie. Our object of study is Norbert Elias's On the Process of Civilization. The pragmatic genealogy of this book reveals the importance of taking materiality seriously. By documenting the successive entanglements between human agency and nonhuman factors, we discuss the origins of the book in the 1930s, how it was forgotten for 30 years, and how in the mid-1970s it became a sociological classic. We explain canonization as a matter of fusion between book's material form and its content, in the context of the paperback revolution of the 1960s, the events of May 1968, and the demise of Parsons' structural functionalism, and how this provided Elias with an opportunity to advance his model of sociology.

  14. [Colective process of knowledge production in health: an overview in hospital nursing practice].

    PubMed

    Meyer, Dagmar Elisabeth Estermann

    2006-01-01

    The article presents some reflections based on the authors'participation in a workshop when the subject: colective processes of knowledge production in health was discussed. Based on other authors' ideas such as Michel Focault and Norbert Elias, the author's discussion concerns some dimensions over that process in a particular knowledge considering the hospital setting and also the position of specific nursing know-how in the context of professional practice (nursing records), with central focus in the work, the disease, and the sick body. In that direction the text is structured around three inter-related/dependent central questions: which knowledge configure nursing know how in hospital context? Which registered knowledge reinforce, legitimate and feed-back the nursing know how? How does this process occur, what and for who are those effects?

  15. [Project HOPE contribution to the setting up of the professional identity of the first nurses from Alagoas, 1973-1977].

    PubMed

    Costa, Laís de Miranda Crispim; dos Santos, Regina Maria; Santos, Tânia Cristina Franco; Trezza, Maria Cristina Soares Figueiredo; Leite, Josete Luzia

    2014-01-01

    Social-historical study conducted to examine the contribution of the American Nurses of Project HOPE to the configuration of the professional identity of the first trained nurses in Alagoas, in the period of 1973-1977. The theoretical framework was the "Civilizing Process" of Norbert Elias. Primary sources were official documents and personal files of 13 respondents by oral history; the secondary sources were authors of the History of Brazil/Alagoas. Data analysis showed that the configuration of the professional identity of the first trained nurses in Alagoas was a civilizing process, with all the nuances that make up the power relations. There was a significant contribution of American Nursing. However the movement of resistance to this domination was very strong, resulting in a Course that could take advantage of technological advancement and prestige brought by the United States, to build a unique Nursing from the social fabric embroidery at this meeting with so many different cultures.

  16. [Gender relations and interdependence: reflections on changes in the hospital configuration].

    PubMed

    Pereira, Audrey Vidal; Rotenberg, Lúcia; Oliveira, Simone Santos

    2013-01-01

    The article analyzes changes that have occurred in hospitals over the years, with a focus on the dynamics of gender relations as experienced by healthcare workers. We use the notions of configuration and interdependence, taken from Norbert Elias' theory of the civilizing process, along with discussions of gender relations at work; drawing from Michel Foucault, we also reference the disciplinary practices employed down through hospital history. This linkage of discussions on gender issues and on interdependent relations opens up to a reflection on conflicts of interests, power struggles, and the balance of tensions, which in turn makes it possible to problematize gender inequalities with the ultimate aim of achieving an interdisciplinary effort that will promote health care of an integral nature.

  17. Novel procedure for characterizing nonlinear systems with memory and combating the curse of dimensionality

    NASA Astrophysics Data System (ADS)

    Nuttall, A. H.; Katz, R. A.; Hughes, D. R.; Koch, R. M.

    2015-10-01

    A well-known mathematical model for characterizing nonlinear systems was originally proposed by Vito Volterra (1860-1940) and later developed by Norbert Wiener (1894-1964). More recently, Albert Nuttall, working with coauthors, has made substantial improvements to Wiener's approach, in which kernel estimates are modeled directly rather than computed from Wiener functionals. Other enhancements made include kernel estimation using a least-square approach for obtaining a best fit to the measured system response, and procedural methods to obtain uncorrelated column-wise basis vectors in the design matrix. These techniques, among others, include: maximally-sparse sampling of the kernels (for first-, second- and third-order), combatting ill-conditioning on its own terms, and realizing an exponential decrease of the growth of the number of kernel coefficients.

  18. [Rachel Haddock Lobo: her professional life and her contribution to REBEn].

    PubMed

    Santos, Tânia Cristina Franco; Oliveira, Sonô Taíra

    2002-01-01

    This is a historical study that analyses the formation process of the professional habitus of Rachel Haddock Lobo through the reconstruction of her biography. It also analyses her contribution as 1st editor in chief of Revista Annaes de Enfermagem (Brazilian Journal of Nursing), in 1932, which is currently called Revista Brasileira de Enfermagem. The preferential primary sources of this study included written documents and the oral testimony of one of Rachel Haddock Lobo's family members. Both sources were obtained from Centro de Documentação da Escola de Enfermagem Ana Nery (Documentation Center of Ana Neri School of Nursing). Data were analyzed through the concepts of habitus and social configuration by Norbert Elias. The analysis showed that Rachel Haddock Lobo gave expressive contribution to the creation process of the journal referred, which, on its turn, had an strategic importance on the formation of the identity of the Brazilian nursing professionals at that time.

  19. Felt stigma and obesity: introducing the generalized other.

    PubMed

    Barlösius, Eva; Philipps, Axel

    2015-04-01

    People with a big body are tainted in western societies. Although most research on obesity occurs in the medical context, few studies investigate characteristics and effects of feelings and fears related to the fat stigma in the absence of overt discrimination. By linking Norbert Elias's and George H. Mead's theoretical frameworks, this paper offers a different approach to understanding and investigating felt stigma. The study is based on secondary data (25 semistructured interviews with children and adolescents). It explores internalized societal perspectives on overweight and obesity and inquires into the way in which interviewees handle the blame frame of personal responsibility during their interview. The preliminary findings suggest that specific forms of managing one's self-presentation in interviews indicate felt stigma. Consequently, the paper argues for an analytical approach that extends the focus on the content of interviews to include its dynamics.

  20. Heliophysics: Active Stars, their Astrospheres, and Impacts on Planetary Environments

    NASA Astrophysics Data System (ADS)

    Schrijver, C. J.; Bagenal, F.; Sojka, J. J.

    2016-04-01

    Preface; 1. Introduction Carolus J. Schrijver, Frances Bagenal and Jan J. Sojka; 2. Solar explosive activity throughout the evolution of the Solar System Rachel Osten; 3. Astrospheres, stellar winds, and the interstellar medium Brian Wood and Jeffrey L. Linsky; 4. Effects of stellar eruptions throughout astrospheres Ofer Cohen; 5. Characteristics of planetary systems Debra Fischer and Ji Wang; 6. Planetary dynamos: updates and new frontiers Sabine Stanley; 7. Climates of terrestrial planets David Brain; 8. Upper atmospheres of the giant planets Luke Moore, Tom Stallard and Marina Garland; 9. Aeronomy of terrestrial upper atmospheres David E. Siskind and Stephen W. Bougher; 10. Moons, asteroids, and comets interacting with their surroundings Margaret G. Kivelson; 11. Dusty plasmas Mihály Horányi; 12. Energetic-particle environments in the Solar System Norbert Krupp; 13. Heliophysics with radio scintillation and occultation Mario M. Bisi; Appendix 1. Authors and editors; List of illustrations; List of tables; References; Index.

  1. Proceedings of: 2005 Particle Acceleration Confence

    SciTech Connect

    Henderson, Stuart

    2006-01-01

    The 21st Particle Accelerator Conference, PAC05, took place at the Knoxville Convention Center (KCC) from Monday through Friday, May 16-20, 2005. Sponsored by the American Physical Society (APS), the Institute of Electrics and Electronics Engineers (IEEE) with its subdivision of Nuclear and Plasma Sciences Society (NPSS), the conference was hosted by the Oak Ridge National Laboratory (ORNL) Spallation Neutron Source (SNS) Project and Thomas Jefferson National Accelerator Facility (JLab). The conference was chaired by Norbert Holtkamp, and the Local Organizing Committee was made up of staff from the ORNL SNS Project under the chairmanship of Stuart Henderson. The conference welcomed over 1400 delegates from the United States, Europe, Asia, the Middle East, South America and from as far away as Australia. Almost 1400 papers where processed during the conference and will be published on the Joint Accelerator Conferences Website (JACoW) page.

  2. Unmanned Evaluation of the U.S. Navy MK 15 Closed-Circuit UBA (underwater Breathing Apparatus).

    DTIC Science & Technology

    1983-07-01

    FUNCTIONAL DESCRIPTION (Figure 5) The MK 15 is a closed circuit rebreather capable of providing approximately 595 liters (21 cu. ft.) of both 02 and a...8217Evaluation of Modified DRAEGER LAR V Closed - Circuit Oxygen Rebreather ,’ James R. Middleton and Claude A. Piantadosi, August i979. 4. NEDU Report 2-80...8217 Unmanned Evaluation of U.S. Navy UBA EX-16 Pre-production Model Closed Circuit Rebreather ,’ James R. Middleton, December 1979. 13 -p.ItI)1& A%0

  3. ["Kaitai-Shinsho": a change of languages and concepts].

    PubMed

    Okada, Masanobu

    2003-07-01

    The translation of "Outleedkundige Tafelen (Dutch) [Anatomische Tabellen (German)]" to "Kaitai-Shinsho" by Gempaku Sugita and others was not the mere substitution of Dutch for Japanese. They responded to the writing according to the situation of the change to modern medicine from the medicine of ancient-medieval times based on Galen's teachings, by using the Japanese culture of those days in a form of "bricolage" (a term used by Claude Levi-Strauss), in combination with Western medicine, leading to its establishment as Japanese medicine. That is, their work was not a mere translation, but an innovation of Japanese medical language system.

  4. International Conference on the Physics of Electronic and Atomic Collisions. Participants List (16th), Held in New York, New York on 26 July-1 August 1989

    DTIC Science & Technology

    1989-08-01

    AVE.LINCOLN, NE 68509-0111 CEDEX, MENLO PARK, CA 94025 USA FRANCE USA RONALD A. PHANEUF JEAN - CLAUDE POIZATOAK RIDGE NAT’L LAB ARTHUR V. PHELPS UNIVERSITE...SHABANA GAIYOOM JEAN W. GALLAGHER LATVIAN ACAD. SCI. UNIV COLLEGE LONDON N.I.S.T. RTGA, GOWER ST. A323 PHYSICS BLDG. USSR LONDON, WCIE 6BT GAITHERSBURG...TOKYO, 102 D-6300 GIESSEN, USA JAPAN FRG MANFRED SALZMAN DOUGLAS H. SAMPSON JOSEPH SANDERSON TELTOWER DAMM 223B PENN STATE UNIV UNIV COLLEGE LONDON

  5. Study of Semiconductor Clusters by Local Inverse Photo Emission

    DTIC Science & Technology

    1991-01-01

    00511 91 5 24 0’ 5 IU!tl/H~illi~~ STM Publications Semiconductors and Surfaces Dror Sarid , Brian P. McGinnis, and Tammy D. Henson, "Four-wave mixing...Los Angeles 10-17 January (1988). Dror Sarid , Tammy D. Henson, L. Stephen Bell, and Claude J. Sandroff, "Scanning tunneling microscopy of semiconductor...clusters,"J. Vac. Sci. and Tech. A 6, 424 (1988). Dror Sarid , Tammy D. Henson, Neal Armstrong, and L. Stephen Bell, "Probing of Basal Planes of MoS 2

  6. STS-46 ESA MS Nicollier and PLC Hoffman pose on OV-104's aft flight deck

    NASA Technical Reports Server (NTRS)

    1992-01-01

    STS-46 European Space Agency (ESA) Mission Specialist (MS) Claude Nicollier (left) and MS and Payload Commander (PLC) Jeffrey A. Hoffman pose in front of the onorbit station controls on the aft flight deck of Atlantis, Orbiter Vehicle (OV) 104. The overhead windows W7 and W8 appear above their heads and the aft flight deck viewing windows W9 and W10 behind them. Hoffman and Nicollier have been training together for a dozen years at JSC. Hoffman was an astronaut candidate in 1978 and Nicollier accompanied a group of trainees in 1980. Note the partially devoured chocolate Space Shuttle floating near the two.

  7. Congenital Horner Syndrome with Heterochromia Iridis Associated with Ipsilateral Internal Carotid Artery Hypoplasia

    PubMed Central

    Coulier, Julie; Rommel, Denis; Boschi, Antonella

    2015-01-01

    Background Horner syndrome (HS), also known as Claude-Bernard-Horner syndrome or oculosympathetic palsy, comprises ipsilateral ptosis, miosis, and facial anhidrosis. Case Report We report herein the case of a 67-year-old man who presented with congenital HS associated with ipsilateral hypoplasia of the internal carotid artery (ICA), as revealed by heterochromia iridis and confirmed by computed tomography (CT). Conclusions CT evaluation of the skull base is essential to establish this diagnosis and distinguish aplasia from agenesis/hypoplasia (by the absence or hypoplasia of the carotid canal) or from acquired ICA obstruction as demonstrated by angiographic CT. PMID:25749818

  8. STS-46 MS Nicollier and Payload Specialist Malerba during JSC egress training

    NASA Technical Reports Server (NTRS)

    1992-01-01

    STS-46 Atlantis, Orbiter Vehicle (OV) 104, European Space Agency (ESA) Mission Specialist (MS) Claude Nicollier (left) and Italian Payload Specialist Franco Malerba, wearing launch and entry suits (LESs) and launch and entry helmets (LEHs), pose on the poolside of JSC's Weightless Environment Training Facility (WETF) Bldg 29. The two crewmembers are preparing for a launch emergency egress (bailout) simulation during which they will be dropped into the WETF pool. After landing in the water they will test crew escape system (CES) equipment and flotation devices.

  9. [Autonomic nervous system disorders in 230 cases of basilar impression and Arnold-Chiari deformity].

    PubMed

    da Silva, J A; Brito, J C; da Nóbrega, P V

    1992-11-01

    Within the period of 1971 to 1989 we operated on 230 cases of craniocervical malformations characterised by 189 cases of basilar impression associated with Arnold-chiari malformation, 28 cases of isolated basilar impression and 13 cases of Arnold-Chiari malformation. Autonomic disturbance was observed in 136 (59.1%) cases: sexual disorders like reduced potency and impotency were observed in 86 (60.9%) out of 141 male patients, urinary symptoms in 39 (17%) patients; and other autonomic features like dyspnea, anhidrosis, hyperhidrosis, Claude Bernard-Horner syndrome and constipation in 41 (17.8%) patients.

  10. The Diplomacy of the Jaguar: French Airpower in Postcolonial African Conflicts

    DTIC Science & Technology

    2009-03-01

    flying from N’Djamena to support CAR forces trying to repel Chadian 5 rebel columns. Throughout the operation, Atlantic mari - time patrol aircraft from...Claude d’Abzac, Marie -Catherine Dubreil, and François Pernot. Abrégé d’histoire de l’aéronautique militaire et de l’Armée de l’air. Paris, France...America, 1994. Smith, Dan. Penguin Atlas of War and Peace. 4th edition. New York: Penguin, 2003. Somerville , Keith. Foreign Military Intervention in Africa

  11. Experimenting with styles of living: Bernard, Canguilhem and type 2 diabetes education.

    PubMed

    Ljungdalh, Anders Kruse

    2013-09-01

    The paper links a debate in the history of medical science between statistics and the experimental method with contemporary diabetes educational practices. An empirical example of a tension between neglect and concern in diabetes self-regulation frames the subsequent theoretical discussion between first, Claude Bernard and statistics and afterwards, Georges Canguilhem as a correlative to Bernard. Through these philosophers of medical science a connection between the experimental method and education is demonstrated. Finally, a case description of an experimental approach to alcohol and experimentation frames and highlights the educational aspect of the methodological discussion.

  12. Taking a geometric look at the socio-political functioning schemes of the living. Catastrophe theory and theoretical sociology.

    PubMed

    Morier, Clément

    2013-09-01

    The aim of this communication is to consider morphological processes in sociology, mainly through the study of the stability of forms of sociality. At the same time, it aims to study the regulation of constraints, related to an increasingly conflictual environment, through political organization. We use a specific theoretical framework: the catastrophe theory developed by René Thom in topology, further developed by Claude Bruter from a physics point of view, and reworked by Jacques Viret in biology. The idea is to show the existence of archetypal processes organizing social forms.

  13. STS-46 ESA MS Nicollier conducts IFM on OV-104's waste collection system

    NASA Technical Reports Server (NTRS)

    1992-01-01

    STS-46 European Space Agency (ESA) Mission Specialist (MS) Claude Nicollier, wearing goggles, face mask, and rubber gloves, reviews inflight maintenance (IFM) checklist procedures before starting waste collection system (WCS) fan separator repair. One of two fan separators used to transfer waster water from the waste management compartment (WMC) to the waste water tank has failed. The suspected accumulation of water in the separator was believed to have occurred during a test dumping of waste water at a lower than normal pressure to evaluate the performance of new nozzles. The WMC is located on the middeck of Atlantis, Orbiter Vehicle (OV) 104.

  14. Introduction

    NASA Astrophysics Data System (ADS)

    Eberly, J. H.

    1998-04-01

    The past few years have seen remarkable developments in the ability to control atomic motion by optical techniques. Among the key tools that have been developed for this purpose are the techniques of laser cooling, the significance of which was recognized by the award of the 1997 Nobel Prize in Physics to Steven Chu, Claude Cohen-Tannoudji, and William Phillips. These techniques have made it possible to cool atoms to temperatures lower than have been produced in any other physical system - around 10(-8) degrees Kelvin above absolute zero - and to confine those in traps for extended periods of observation.

  15. The Space Shuttle Columbia clears the tower to begin the mission. The liftoff occurred on schedule

    NASA Technical Reports Server (NTRS)

    1996-01-01

    STS-75 LAUNCH VIEW --- The Space Shuttle Columbia clears the tower to begin the mission. The liftoff occurred on schedule at 3:18:00 p.m. (EST), February 22, 1996. Visible at left is the White Room on the orbiter access arm through which the flight crew had entered the orbiter. Onboard Columbia for the scheduled two-week mission were astronauts Andrew M. Allen, commander; Scott J. Horowitz, pilot; Franklin R. Chang-Diaz, payload commander; and astronauts Maurizio Cheli, Jeffrey A. Hoffman and Claude Nicollier, along with payload specialist Umberto Guidioni. Cheli and Nicollier represent the European Space Agency (ESA), while Guidioni represents the Italian Space Agency (ASI).

  16. A remote camera at Launch Pad 39B, at the Kennedy Space Center (KSC), recorded this profile view of

    NASA Technical Reports Server (NTRS)

    1996-01-01

    STS-75 LAUNCH VIEW --- A remote camera at Launch Pad 39B, at the Kennedy Space Center (KSC), recorded this profile view of the Space Shuttle Columbia as it cleared the tower to begin the mission. The liftoff occurred on schedule at 3:18:00 p.m. (EST), February 22, 1996. Onboard Columbia for the scheduled two-week mission were astronauts Andrew M. Allen, commander; Scott J. Horowitz, pilot; Franklin R. Chang-Diaz, payload commander; and astronauts Maurizio Cheli, Jeffrey A. Hoffman and Claude Nicollier, along with payload specialist Umberto Guidioni. Cheli and Nicollier represent the European Space Agency (ESA), while Guidioni represents the Italian Space Agency (ASI).

  17. Summer Research Program (1992). Graduate Student Research Program (GSRP) Reports. Volume 10. Wright Laboratory

    DTIC Science & Technology

    1992-12-28

    Uplander Way Culver City CA 90230-6600 AFOSR/NI 110 Duncan Ave., Suite Bl15 Bldg 410 Bolling AFB DC 20332-0001 Lt Col Claude favender -;L ’,1E’N f NCS...macro until all titles art on the same line. A single title line consist of the tides on line I and their units on line 2. 2) unwrapruth Why needed...this section, we briefly review the state-of-the- art in polarinietric target detection. WVe thlen propose a new approach which treats the target

  18. The Antiaircraft Journal. Volume 95, Number 4, July-August 1952

    DTIC Science & Technology

    1952-08-01

    It stood out like a painted picture in green in an ocean of blue . Oval in shape, the surf break- ing on the white beaches, its coconut trees swaying in...trying to’ find a life raft in the vast blue ocean was like hunting the pro- verbial needle in a haystack. At times we would spot an autline on the...water that strangly resembled a raft, but an gaing dawn to examine it found it to be a cluster of seaweed ar merely the shadaw af a claud an the blue

  19. Ambient Noise and Surface Wave Dissipation in the Ocean

    DTIC Science & Technology

    1993-06-21

    9 Ckq0 s I I follows hm the rlgi-hanmd nru A third coordinate system based on the wire wave gauge array was also defined such that the army x-axis...their research followed up in the literatum As we mentioned in our review, the research in wave and ambient noie relationship is relatively sparse. We...I AD-A279 650 AM’BIET NOISE AND SURFACE WAVE DISSIPATION IN THE OCEAN Q) I by S.tais C. Feliardo S. in C invl I Wagm Claude, 1985 Unhiaity of the

  20. The United States, Vietnam, and the National Interest.

    DTIC Science & Technology

    1981-03-01

    California THESIS 1: ) THE UNITED STATES, VIETNAM, AND THE NATIONAL INTEREST, by John G.: Karas MarcA -98l Thesis Advisor: Claude A. Buss Approved for public...the use of the atomic bomb against Japan. As it had throughout World War II, the United States in the immediate postwar era continued to pay primary...relatively freely, were now required to not only pay taxes but were also required to pay rent to landlords who sat safely in Saigon. Under pressure from the

  1. F.S.V.B. Volleyball

    SciTech Connect

    2006-06-07

    22me assemblée des délégués de la Fédération Suisse de Volley Ball (F.S.V.B.), en présence entre autres de Claude Delay, représentant de la société fédérale de gymnastique et Hans Gauer, représentant de l'association suisse de gymnastique féminine. Annonce d'une démonstration d'un mini match de volley ball à Meyrin dans l'après-midi.

  2. Multiscale Problems in Materials Science: A Mathematical Approach to the Role of Uncertainty

    DTIC Science & Technology

    2012-10-01

    Claude Lebris, F. Legoll, F. Thomines Ecole Nationale des Ponts et Chaussées 6-8, Avenue Blaise Pascal Marne la Vallée 77455, France...5d. TASK NUMBER 5e. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Ecole Nationale des Ponts et Chaussées 6-8, Avenue Blaise ... Pascal Marne la Vallée 77455, France 8. PERFORMING ORGANIZATION REPORT NUMBER N/A 9. SPONSORING/MONITORING AGENCY NAME(S) AND ADDRESS

  3. Feasibility of MR-Based Body Composition Analysis in Large Scale Population Studies

    PubMed Central

    West, Janne; Dahlqvist Leinhard, Olof; Romu, Thobias; Collins, Rory; Garratt, Steve; Bell, Jimmy D.; Borga, Magnus; Thomas, Louise

    2016-01-01

    Introduction Quantitative and accurate measurements of fat and muscle in the body are important for prevention and diagnosis of diseases related to obesity and muscle degeneration. Manually segmenting muscle and fat compartments in MR body-images is laborious and time-consuming, hindering implementation in large cohorts. In the present study, the feasibility and success-rate of a Dixon-based MR scan followed by an intensity-normalised, non-rigid, multi-atlas based segmentation was investigated in a cohort of 3,000 subjects. Materials and Methods 3,000 participants in the in-depth phenotyping arm of the UK Biobank imaging study underwent a comprehensive MR examination. All subjects were scanned using a 1.5 T MR-scanner with the dual-echo Dixon Vibe protocol, covering neck to knees. Subjects were scanned with six slabs in supine position, without localizer. Automated body composition analysis was performed using the AMRA Profiler™ system, to segment and quantify visceral adipose tissue (VAT), abdominal subcutaneous adipose tissue (ASAT) and thigh muscles. Technical quality assurance was performed and a standard set of acceptance/rejection criteria was established. Descriptive statistics were calculated for all volume measurements and quality assurance metrics. Results Of the 3,000 subjects, 2,995 (99.83%) were analysable for body fat, 2,828 (94.27%) were analysable when body fat and one thigh was included, and 2,775 (92.50%) were fully analysable for body fat and both thigh muscles. Reasons for not being able to analyse datasets were mainly due to missing slabs in the acquisition, or patient positioned so that large parts of the volume was outside of the field-of-view. Discussion and Conclusions In conclusion, this study showed that the rapid UK Biobank MR-protocol was well tolerated by most subjects and sufficiently robust to achieve very high success-rate for body composition analysis. This research has been conducted using the UK Biobank Resource. PMID:27662190

  4. New Revolutionary Possibilities in Geodesy Providing the Discoveries Awarded for Physics in 2005 and 1997

    NASA Astrophysics Data System (ADS)

    Solaric, N.; Solaric, M.; Svehla, D.

    2012-03-01

    Nobel Prize for Physics in the year 2005 was awarded to Roy J. Glauber, John L. Hall and Theodor W. Hänsch in recognition of their contribution in the field of optics. Nobel Prize for physics in 1997 was awarded to Steven Chu, Claude Cohen-Tannoudji and William D. Phillips for the discovery and development of the method by means of which the atoms are cooled down and trapped by laser light. The improvements that were suggested by Theodor W. Hänsch and John L. Hall supported by the discoveries made by Steven Chu, Claude Cohen-Tannoudji and William Phillips offer new revolutionary possibilities for significant improvement of measuring accuracy in geodesy and also in many other fields of science and application. By means of optical clocks it will be possible to measure time even more precisely than by atomic clocks, providing thus more precise determination of navigational satellite orbits, and consequently the positions of points on the Earth's surface. It also opens the possibility of determining the difference of gravitational potential between the points on the Earth's surface applying thereby the theory of relativity by Einstein. In this way it will be possible to connect the heights between the continents by means of direct measurements, and also to improve the connection of levelling networks between individual countries on the continents. More precise distance measurements will also bi provided.

  5. Operational experience of the OC-OTEC experiments at NELH

    SciTech Connect

    Link, H

    1989-02-01

    The Solar Energy Research Institute, under funding and program direction from the US Department of Energy, has been operating a small-scale test apparatus to investigate key components of open- cycle ocean thermal energy conversion (OC-OTEC). The apparatus started operations in October 1987 and continues to provide valuable information on heat-and mass-transfer processes in evaporators and condensers, gas sorption processes as seawater is depressurized and repressurized, and control and instrumentation characteristics of open-cycle systems. Although other test facilities have been used to study some of these interactions, this is the largest apparatus of its kind to use seawater since Georges Claude`s efforts in 1926. The information obtained from experiments conducted in this apparatus is being used to design a larger scale experiment in which a positive net power production is expected to be demonstrated for the first time with OC-OTEC. This paper describes the apparatus, the major tests conducted during its first 18 months of operation, and the experience gained in OC-OTEC system operation. 13 refs., 8 figs.

  6. [The Helvetius dynasty].

    PubMed

    Van Heiningen, Teunis Willem

    2014-01-01

    The Helvetius dynasty originates from the Principality of Anhalt, in Germany. George Vigelius, one of its ancestors, was born in the Palatinate (Germany) and studied theology in the town of Basel (Switzerland), after which he was given the surname Swietser. In 1649, his eldest son, Johann Friedrich Swietser, moved to the United Provinces and changed his name into Johan Frederik Helvétius. In 1656, he took his doctorate of medicine at the university of Harderwyck Guelderland). He settled in Amsterdam and moved later to The Hague, where he had a lightning career. Three of his four sons studied medicine in Leyden: Jean-Balthasar, Philippe-Maximilien, and Joseph-Jean. Jean-Adrien, the second son of Johann-Friedrich, settled in Paris and took his doctorate of medicine at the university of Reims, using the pseudonym of Christian-Lebrecht Helvétius. He had a prosperous career. He was the father of Jean-Claude-Adrien Helvétius, who became also a successful physician and first physician to the queen of France. His grandson was Claude-Adrien Helvétius, who became a leading philosopher and writer.

  7. Physiological regulation through learnt control of appetites by contingencies among signals from external and internal environments.

    PubMed

    Booth, David A

    2008-11-01

    As reviewed by [Cooper, S. J. (2008). From Claude Bernard to Walter Cannon: emergence of the concept of homeostasis. Appetite 51, 419-27.] Claude Bernard's idea of stabilisation of bodily states, as realised in Walter B. Cannon's conception of homeostasis, took mathematical form during the 1940s in the principle that externally originating disturbance of a physiological parameter can feed an informative signal around the brain to trigger counteractive processes--a corrective mechanism known as negative feedback, in practice reliant on feedforward. Three decades later, enough was known of the physiology and psychology of eating and drinking for calculations to show how experimentally demonstrated mechanisms of feedforward that had been learnt from negative feedback combine to regulate exchanges of water and energy between the body and the surroundings. Subsequent systemic physiology, molecular neuroscience and experimental psychology, however, have been traduced by a misconception that learnt controls of intake are 'non-homeostatic', the myth of biological 'set points' and an historic failure to address evidence for the ingestion-adapting information-processing mechanisms on which an operationally integrative theory of eating and drinking relies.

  8. ESA astronauts assigned to Tethered Satellite System mission - STS-75

    NASA Astrophysics Data System (ADS)

    1995-01-01

    The TSS project is a joint NASA/ASI (Italian Space Agency) effort. On STS-75, the five-foot diameter (1.6 metre) Italia built satellite is scheduled to be deployed on the end of a 1 mile long (20 kilometre) conductive tether to study the electrodynamic effects of moving such a tether through the Earth's magnetic field. The experiment will also test techniques for managing the tethered spacecraft at great distances. Throughout the 13-day flight, additional experiments housed in the orbiter's payload bay will give scientists access to s for microgravity and fundamental science investigations. The USMP is designed to provide the foundation for advanced scientific investigations similar to those planned aboard the International Space Station. Claude Nicollier, who is Swiss, was selected by ESA in 1978 as one of three European payload specialists to train for the SPACELAB-1 mission. He was a mission specialist on STS- 46 (31 July-8 August 1992), during which the crew members deployed ESA's retrievable science platform (EURECA) and conducted the first TSS test flight. A few months after his return from this mission Claude Nicollier was selected as mission specialist for STS-61 (2-13 December 1993). He contributed considerably to the complete success of the Hubble Space Telescope repair and refurbishment mission and in particular the replacement of the ESA-provided solar arrays. Maurizio Cheli, an Italian, was selected by ESA in May 1992 along with five other young candidates to expand the corps of ESA astronauts. He has been in Houston since mid-1992 and has qualified as mission specialist at NASA's Johnson Space Center there. STS-75 will be his first Shuttle flight. Marine Corps Lt. Col. Andrew M. Allen will command Space Shuttle Columbia's STS-75 mission. Joining Allen are Air Force Major Scott J. Horowitz, pilot; payload commander Franklin R. Chang-Diaz, Ph. D; Italian Space Agency (ASI) TSS payload specialist Umberto Guidoni, Ph.D; mission specialist Jeffrey A

  9. The New Physics

    NASA Astrophysics Data System (ADS)

    Fraser, Gordon

    2006-04-01

    Introduction Gordon Fraser; Part I. Matter and the Universe: 1. Cosmology Wendy Freedman and Rocky Kolb; 2. Gravity Ronald Adler; 3. Astrophysics Arnon Dar; 4. Particles and the standard model Chris Quigg; 5. Superstrings Michael Green; Part II. Quantum Matter: 6. Atoms and photons Claude Cohen-Tannoudji and Jean Dalibard; 7. The quantum world of ultra-cold atoms Christopher Foot and William Phillips; 8. Superfluidity Henry Hall; 9. Quantum phase transitions Subir Sachdev; Part III. Quanta in Action: 10. Quantum entanglement Anton Zeilinger; 11. Quanta, ciphers and computers Artur Ekert; 12. Small-scale structure and nanoscience Yoseph Imry; Part IV. Calculation and Computation: 13. Nonlinearity Henry Abarbanel; 14. Complexity Antonio Politi; 15. Collaborative physics, e-science and the grid Tony Hey and Anne Trefethen; Part V. Science in Action: 16. Biophysics Cyrus Safinya; 17. Medical physics Nicolaj Pavel; 18. Physics and materials Robert Cahn; 19. Physics and society Ugo Amaldi.

  10. Introduction à L'Etude de la Médecine Expérimentale. Surgical revolution. Part I.

    PubMed

    Toledo-Pereyra, Luis H

    2009-01-01

    Claude Bernard (1813-1878), the most distinguished French physiologist of the 19th century, made incomparable contributions to the world of medicine of his times and even to ours. Bernard believed in scientific determinism and created the term milieu interieur as a manner to better understand experimental medicine and to present a new way of explaining the function of the living organism. Bernard dealt with innovative developments in the glycogenetic function of the liver, extrahepatic glycogenesis, the role of pancreatic juice in the digestion of fats, vasomotor nervous system discoveries, and other important physiological advances. In 1865, Bernard's most extraordinary book on the philosophy and understanding of experimental medicine appeared. This book represented Bernard's unique contribution to the progress of medical and surgical research. Because of the enormous implications of this work on the advancement of surgical research, which were subsequently applied to clinical surgical practice, we propose that this book created a surgical revolution.

  11. An analysis of concert saxophone vibrato through the examination of recordings by eight prominent soloists

    NASA Astrophysics Data System (ADS)

    Zinninger, Thomas

    This study examines concert saxophone vibrato through the analysis of several recordings of standard repertoire by prominent soloists. The vibrato of Vincent Abato, Arno Bornkamp, Claude Delangle, Jean-Marie Londeix, Marcel Mule, Otis Murphy, Sigurd Rascher, and Eugene Rousseau is analyzed with regards to rate, extent, shape, and discretionary use. Examination of these parameters was conducted through both general observation and precise measurements with the aid of a spectrogram. Statistical analyses of the results provide tendencies for overall vibrato use, as well as the effects of certain musical attributes (note length, tempo, dynamic, range) on vibrato. The results of this analysis are also compared among each soloist and against pre-existing theories or findings in vibrato research.

  12. Mendelevium: The Way It Was

    SciTech Connect

    2013-11-05

    A reel of black & white film shot nearly 60 years ago has surfaced at Berkeley Lab, depicting the discovery of Mendelevium - or Element 101 - as reenacted by some of the legendary scientists who did the actual work at that time. Since the 1940s, Berkeley Lab scientists were locked in a race to synthesize new elements, and more often than not, they came out winners. Sixteen elements, most of them in the actinide series at the bottom of the periodic table, were discovered and synthesized by its researchers. Retired Berkeley Lab physicist Claude Lyneis found the reel in a box of dusty and deteriorating films slated for disposal. Using digital editing skills he acquired to make videos of his son's lacrosse team, Lyneis has produced and narrated an excerpt of this nearly-lost footage. It is an entertaining and informative look at the pioneering physics performed at UC Berkeley and Lawrence Berkeley National Laboratory's hillside campus.

  13. [THE SCIENTIFIC REVOLUTION IN MEDICINE OF THE LAST QUARTER OF XIX-FIRST HALF OF XX CENTURIES. REPORT II. THE OUTSET OF REVISION OF MEDICAL SCIENCE].

    PubMed

    Stochik, A M; Zatravkin, S N

    2015-01-01

    The article affirms that onset of revision of picture of analyzed reality, methodological approaches to studying of vital activity of human organism and philosophical basics of medical science refers to 1878 and is related to publishing of "The course of general physiology" by French physiologist Claude Bernard. The implemented analysis of the text of this work permit to establish that C. Bernard undertook an attempt to introduce conception of human organism as a processing system being self-reproduced as. a result of interaction with environment due to mechanisms of self-regulation. The necessity was substantiated to make experiment the leading method of cognition of vital activity. The living wholeness (organism, cell) was proposed to be an object of experimentation. In this living wholeness its natural capacities to self-regulation of main vital processes can be preserved at its maximum. The new senses were introduced into ontological categories of thing, process, causality, portion and whole.

  14. Growing Evidence about the Relationship between Vessel Dissection and Scuba Diving.

    PubMed

    Brajkovic, Simona; Riboldi, Giulietta; Govoni, Alessandra; Corti, Stefania; Bresolin, Nereo; Comi, Giacomo Pietro

    2013-01-01

    Carotid and vertebral artery dissection are relatively frequent and risky conditions. In the last decade, different patients with extracranial (and in 1 case also intracranial) dissections associated with the practice of scuba diving were reported. The connection between the two conditions has not been fully explained so far. In the present article, we report the case of a patient presenting with Claude Bernard-Horner syndrome and homolateral XII cranial nerve palsy, manifesting a few days after diving in the cold water of a lake. The patient ended up having internal carotid artery dissection associated with the formation of a pseudoaneurysm. Here, we offer a summary of all cases reported in the literature about scuba diving and arterial dissection, and provide a critical discussion about which scuba diving-related factors can trigger the dissection of cervical vessels.

  15. A brief review of molecular information theory

    PubMed Central

    Schneider, Thomas D.

    2011-01-01

    The idea that we could build molecular communications systems can be advanced by investigating how actual molecules from living organisms function. Information theory provides tools for such an investigation. This review describes how we can compute the average information in the DNA binding sites of any genetic control protein and how this can be extended to analyze its individual sites. A formula equivalent to Claude Shannon’s channel capacity can be applied to molecular systems and used to compute the efficiency of protein binding. This efficiency is often 70% and a brief explanation for that is given. The results imply that biological systems have evolved to function at channel capacity, which means that we should be able to build molecular communications that are just as robust as our macroscopic ones. PMID:22110566

  16. Hearing Science in Mid-Eighteenth-Century Britain and France

    PubMed Central

    Gouk, Penelope; Sykes, Ingrid

    2011-01-01

    Benjamin Martin, the English natural philosopher, and Claude-Nicolas Le Cat, the French surgeon, both published important work on auditory physiology and function in the mid-eighteenth century. Despite their different backgrounds, there was consensus between the two scholars on key principles of hearing research, most notably the importance of the inner ear in relation to auditory perception. Martin's work (1755 [1763?]) drew directly on the surgical work of Le Cat (1741) to demonstrate the importance of the auditory mechanism in listening processes. Le Cat's interest in the ear, however, came in turn from his interest in surgical anatomy. Martin used Le Cat's elegant designs as a tool for the vivid communication of auditory function to a popular, fee-paying audience. The meeting of two very different minds through intellectual agreement and material transfer demonstrates the way in which principles of hearing science were established in the Enlightenment period. PMID:20634220

  17. Bruner's Search for Meaning: A Conversation between Psychology and Anthropology.

    PubMed

    Mattingly, Cheryl; Lutkehaus, Nancy C; Throop, C Jason

    2008-03-01

    We introduce a special issue of Ethos devoted to the work of Jerome Bruner and his careerlong attempts to seek innovative ways to foster a dialogue between psychology and anthropology. The articles in this special issue situate Bruner's meaning-centered approach to psychology and his groundbreaking work on narrative in the broader context of the developmental trajectory of both of fields of inquiry. Bruner's work has been enormously influential in the subfields of cultural psychology and psychological anthropology, especially because of his important contributions to our understanding of the intimate relationship between culture and mind. We examine Bruner's past and ongoing engagement with such luminary figures as Lev Vygotsky, Jean Piaget, Alfred Kroeber, Claude Lévi-Strauss, and Clifford Geertz to highlight points of convergence and tension between his version of cultural psychology and contemporary theorizing and practice in psychological anthropology. We also review his practical and theoretical contributions to the fields of medicine, law, and education.

  18. Let it burn: distinguishing inflammable airs 1766-1790.

    PubMed

    Tomory, Leslie

    2009-11-01

    The issue of the number of species of inflammable air was debated particularly in the period 1777-1786. The work of Henry Cavendish in 1766 and Alessandro Volta in 1777 in characterising two species of inflammable air set the stage for the work of other chemists, particularly in Paris, as they debated this question, mostly concerning heavy inflammable air. Different ways of generating gases were discovered up to 1783, when the synthesis of water and the proposal of carbon as an element created a framework for the question to be answered. In 1785-1786, Claude-Louis Berthollet reported the composition of heavy inflammable air and volatile alkali, while Philippe Gengembre analysed phosphorated hydrogen and hepatic air. In the end, it was the new chemical nomenclature of 1787 that spread their results widely.

  19. Whether weather affects music

    NASA Astrophysics Data System (ADS)

    Aplin, Karen L.; Williams, Paul D.

    2012-09-01

    The creative output of composers, writers, and artists is often influenced by their surroundings. To give a literary example, it has been claimed recently that some of the characters in Oliver Twist and A Christmas Carol were based on real-life people who lived near Charles Dickens in London [Richardson, 2012]. Of course, an important part of what we see and hear is not only the people with whom we interact but also our geophysical surroundings. Of all the geophysical phenomena to influence us, the weather is arguably the most significant because we are exposed to it directly and daily. The weather was a great source of inspiration for artists Claude Monet, John Constable, and William Turner, who are known for their scientifically accurate paintings of the skies [e.g., Baker and Thornes, 2006].

  20. Na(+)/H(+) antiporter (NHE1) and lactate/H(+) symporters (MCTs) in pH homeostasis and cancer metabolism.

    PubMed

    Counillon, Laurent; Bouret, Yann; Marchiq, Ibtissam; Pouysségur, Jacques

    2016-10-01

    The Na(+)/H(+)-exchanger NHE1 and the monocarboxylate transporters MCT1 and MCT4 are crucial for intracellular pH regulation, particularly under active metabolism. NHE1, a reversible antiporter, uses the energy provided by the Na(+) gradient to expel H(+) ions generated in the cytosol. The reversible H(+)/lactate(-) symporters MCT1 and 4 cotransport lactate and proton, leading to the net extrusion of lactic acid in glycolytic tumors. In the first two sections of this article we review important features and remaining questions on the structure, biochemical function and cellular roles of these transporters. We then use a fully-coupled mathematical model to simulate their relative contribution to pH regulation in response to lactate production, as it occurs in highly hypoxic and glycolytic tumor cells. This article is part of a Special Issue entitled: Mitochondrial Channels edited by Pierre Sonveaux, Pierre Maechler and Jean-Claude Martinou.

  1. Potential of proposed open-cycle OTEC experiments to achieve net power

    SciTech Connect

    Link, H F; Parsons, B K

    1986-06-01

    Researchers at the Solar Energy Research Institute (SERI) conducted systems analysis studies to determine the potential of various experiments to produce net power using the Claude open-cycle ocean thermal energy conversion (OTEC) power system. The proposed experiment test site is to be the Natural Energy Laboratory of Hawaii at Keahole Point. We found that net power is unlikely to be produced in experiment sizes that use less than about 195 kg/s (3000 gpm) of cold water, and that flow rates of 420 kg/s (6500 gpm) are necessary to achieve a net-power production of at least one-half the gross-power output of the experiment.

  2. Forces and Motion: Dynamics of the Tethered Satellite

    NASA Technical Reports Server (NTRS)

    1994-01-01

    In this 'Lift off to Learning' series, Loren Shriver, commander of STS 46, and the other members of the mission (Claude Nicollier, Marsha Ivins, Andrew Allen, Jeffrey Hoffman, Franklin Chiang-Diaz, and Franco Maerba) use computer graphics, and physical experiments to explain how the tethered satellite to be deployed during their mission will be raised, how it works, the influence of the Shuttle on the satellite and the satellite's influence on the Shuttle's orbit, the gravitational effects, and other effects concerning the Theoretical Physics used to plan this mission (gravity gradient force, center of mass, angular momentum, centrifugal force, and coriolis effect). This video ends with a discussion of the technology transfer and utilization of this tethered satellite concept and design.

  3. Aging research and education centers in the United States: a compendium.

    PubMed

    Steinecke, A; Ciok, A E

    1997-10-01

    U.S. centers and institutes for research and education devoted to aging are listed. These lists can serve as a starting point for building a more comprehensive reference resource. The first list, U.S. Aging Centers and Institutes, is a general guide to centers or institutes that combine research and education. Subsequent lists are of centers that share missions and funding sources: Geriatric Research, Education and Clinical Centers (GRECCs); Exploratory Centers for Research on Health Promotion in Older Minority Populations; Centers on the Demography of Aging (CDAs); Alzheimer's Disease Centers (ADCs); Claude D. Pepper Older Americans Independence Centers (OAICs); Nathan Shock Centers of Excellence in Basic Biology of Aging; and Roybal Centers for Research on Applied Gerontology. It is hoped that those who work in geriatrics and gerontology in academic medicine will develop a comprehensive system for collecting, updating, and disseminating complete information about the work being done on aging.

  4. Microdebrider cavitation and transcervical removal of parapharyngeal schwannomas approaching the skull base.

    PubMed

    Nicolai, Piero; Paderno, Alberto; Farina, Davide; Piazza, Cesare

    2014-12-01

    Removal of parapharyngeal space (PPS) schwannomas approaching the skull base through a purely transcervical approach requires adequate visualization of the surgical field to obtain complete resection with minimal sequelae. This is a retrospective series of four patients undergoing transcervical removal of sympathetic chain PPS schwannomas abutting the skull base by an intracapsular microdebrider tumor cavitation. Radiologic data, complications, functional outcomes, and follow-up status were considered. MRI was suggestive of PPS schwannoma in all cases, and correctly predicted the nerve of origin in three out of four cases. All patients developed postoperative Claude Bernard-Horner and first-bite syndromes. One patient also presented temporary neuropraxia of the IX cranial nerve, and another of the IX and X cranial nerves. Microdebrider cavitation of sympathetic chain PPS schwannoma abutting the skull base proved to be a reliable technique allowing good visualization of adjacent neural and vascular structures through a purely transcervical approach, while maintaining a low complication rate.

  5. Cosmic Perspectives

    NASA Astrophysics Data System (ADS)

    Biswas, S. K.; Mallik, D. C. V.; Vishveshwara, C. V.

    2008-07-01

    1. Astronomy in ancient and medieval China Joseph Needham; 2. Indian astronomy: an historical perspective B. V. Subbarayappa; 3. Making of astronomy in ancient India Debiprasad Chattopadhyaya; 4. The impact of astronomy on the development of western science Jean-Claude Pecker; 5. Man and the Universe Hubert Reeves; 6. Understanding the Universe - challenges and directions in modern observational astronomy Harlan Smith, Jr: 7. Frontiers in cosmology Fred Hoyle; 8. Did the Universe originate in a big bang? Jayant Narlikar; 9. The dark matter problem Bernard Carr; 10. Geometry and the Universe C. V. Vishveshwara; 11. The origin and evolution of life Cyril Ponnamperuma; 12. The anthropic principle: self selection as an adjunct to natural selection Brandon Carter; 13. Astrology and science: an examination of the evidence Ivan Kelly, Roger Culver and Peter Loptson; 14. Astronomy and science fiction Allen Janis.

  6. Use study of Excerpta Medica abstract journals: to drop or not to drop?

    PubMed Central

    Alligood, E C; Russo-Martin, E; Peterson, R A

    1983-01-01

    The directors of the Claude Moore Health Sciences Library, a medium-sized library serving the University of Virginia medical and nursing schools, were concerned over the increasing cost of periodical subscriptions and so studied the use of the printed copy of Excerpta Medica. This study had six parts: (1) availability in other campus libraries; (2) staff perceptions of in-library use; (3) results of studies performed by other libraries in the United States; (4) recorded in-library use; (5) users' opinions; and (6) personal interviews with library users and with selected departments tht corresponded with the forty-four subject areas of Excerpta Medica. The user-survey parts (4 and 5) elicited few responses, but personal interviews allowed a good look at levels of use and interest. The overall results convinced staff to drop some sections and publicize those that remained. PMID:6626797

  7. Cosmic Perspectives

    NASA Astrophysics Data System (ADS)

    Biswas, S. K.; Mallik, D. C. V.; Vishveshwara, C. V.

    1989-09-01

    1. Astronomy in ancient and medieval China Joseph Needham; 2. Indian astronomy: an historical perspective B. V. Subbarayappa; 3. Making of astronomy in ancient India Debiprasad Chattopadhyaya; 4. The impact of astronomy on the development of western science Jean-Claude Pecker; 5. Man and the Universe Hubert Reeves; 6. Understanding the Universe - challenges and directions in modern observational astronomy Harlan Smith, Jr: 7. Frontiers in cosmology Fred Hoyle; 8. Did the Universe originate in a big bang? Jayant Narlikar; 9. The dark matter problem Bernard Carr; 10. Geometry and the Universe C. V. Vishveshwara; 11. The origin and evolution of life Cyril Ponnamperuma; 12. The anthropic principle: self selection as an adjunct to natural selection Brandon Carter; 13. Astrology and science: an examination of the evidence Ivan Kelly, Roger Culver and Peter Loptson; 14. Astronomy and science fiction Allen Janis.

  8. STS-46 crewmembers and backup payload specialist in JSC WETF egress training

    NASA Technical Reports Server (NTRS)

    1992-01-01

    STS-46 Atlantis, Orbiter Vehicle (OV) 104, Pilot Andrew M. Allen, wearing launch and entry suit (LES) and launch and entry helment (LEH), is assisted by training support personnel as he prepares to simulate a parachute glide into water (the pool) during a launch emergency egress (bailout) simulation in JSC's Weightless Environment Training Facility Bldg 29. Allen holds onto the parachute straps before he is hoisted over the pool. Also in LES gear and waiting along the poolside are (left to right) backup Italian Payload Specialist Umberto Guidoni, Italian Payload Specialist Franco Malerba, and European Space Agency (ESA) Mission Specialist (MS) Claude Nicollier. SCUBA-equipped divers in the pool are seen at the bottom of the frame listening to instructions.

  9. Minding experience: An exploration of the concept of "experience" in the early French anthropology of Durkheim, Lévy-Bruhl, and Lévi-Strauss.

    PubMed

    Throop, C Jason

    2003-01-01

    In line with the growing concern with the unexamined reliance upon the concept of "experience" in anthropology, this article explores in some detail the various usages and definitions of the concept in the work of three of early French anthropology's most influential theorists: Emile Durkheim (1858-1918), Lucien Lévy-Bruhl (1857-1939), and Claude Lévi-Strauss (1908-). With its important influence on both British and American anthropology, the early French anthropological tradition, as epitomized in the writings of these three thinkers, has indeed played a pivotal role in shaping many current taken-for-granted understandings of the concept of experience in the discipline of anthropology as a whole. In the process of exploring how experience is viewed by these three scholars, this paper will thus take some initial steps toward the historical contextualization of many of the unquestioned assumptions underpinning current understandings of experience in the discipline of anthropology and the social sciences more generally.

  10. Hemoglobinopathies in a hospital population in Vancouver.

    PubMed Central

    Gray, G. R.; Marion, R. B.

    1978-01-01

    A number of varieties of thalassemia were found to be common in the Vancouver area and in other parts of British Columbia. Of 3117 patients whose blood samples were studied by hemoglobin electrophoresis at the Vancouver General Hospital between Jan 1, 1965 and June 30,1977, 813 had the beta-thalassemia trait, 18 had homozygous beta-thalassemia, 97 had alpha-thalassemia trait, 24 had hemoglobin H disease and 14 had miscellaneous variants. Eight patients had interactions of beta-thalassemia with hemoglobin S,C, D, O arab or Vancouver, and one patient had alpha thalassemia associated with hemoglobin Constant Spring. Twelve other variants were noted. They included hemoglobins B2, E, Q, GHsi Tsou, J Bangkok, British Columbia, KOLN, Lepore, Rampa, Tacoma, St. Claude and an unidentified alpha-chain variant. PMID:709469

  11. The New Physics

    NASA Astrophysics Data System (ADS)

    Fraser, Gordon

    2009-08-01

    Introduction Gordon Fraser; Part I. Matter and the Universe: 1. Cosmology Wendy Freedman and Rocky Kolb; 2. Gravity Ronald Adler; 3. Astrophysics Arnon Dar; 4. Particles and the standard model Chris Quigg; 5. Superstrings Michael Green; Part II. Quantum Matter: 6. Atoms and photons Claude Cohen-Tannoudji and Jean Dalibard; 7. The quantum world of ultra-cold atoms Christopher Foot and William Phillips; 8. Superfluidity Henry Hall; 9. Quantum phase transitions Subir Sachdev; Part III. Quanta in Action: 10. Quantum entanglement Anton Zeilinger; 11. Quanta, ciphers and computers Artur Ekert; 12. Small-scale structure and nanoscience Yoseph Imry; Part IV. Calculation and Computation: 13. Nonlinearity Henry Abarbanel; 14. Complexity Antonio Politi; 15. Collaborative physics, e-science and the grid Tony Hey and Anne Trefethen; Part V. Science in Action: 16. Biophysics Cyrus Safinya; 17. Medical physics Nicolaj Pavel; 18. Physics and materials Robert Cahn; 19. Physics and society Ugo Amaldi.

  12. F.S.V.B. Volleyball

    ScienceCinema

    None

    2016-07-12

    22me assemblée des délégués de la Fédération Suisse de Volley Ball (F.S.V.B.), en présence entre autres de Claude Delay, représentant de la société fédérale de gymnastique et Hans Gauer, représentant de l'association suisse de gymnastique féminine. Annonce d'une démonstration d'un mini match de volley ball à Meyrin dans l'après-midi.

  13. STS-103 Commander Brown suits up before launch

    NASA Technical Reports Server (NTRS)

    1999-01-01

    STS-103 Commander Curtis L. Brown Jr. is suited up and ready to go for the second launch attempt of Space Shuttle Discovery. The previous launch attempt on Dec. 17 was scrubbed about 8:52 p.m. due to numerous violations of weather launch commit criteria at KSC. Brown and fellow crew members Pilot Scott J. Kelly and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland and Jean-Francois Clervoy of France are scheduled to lift off at 7:50 p.m. EST Dec. 19 on mission STS-103, servicing the Hubble Space Telescope. Objectives for the nearly eight-day mission include replacing gyroscopes and an old computer, installing another solid state recorder, and replacing damaged insulation in the telescope. Discovery is expected to land at KSC Monday, Dec. 27, at about 5:24 p.m. EST.

  14. STS-103 Commander Brown arrives at SLF aboard a T-38 jet for TCDT

    NASA Technical Reports Server (NTRS)

    1999-01-01

    STS-103 Commander Curtis L. Brown Jr. is happy to arrive at Kennedy Space Center to begin Terminal Countdown Demonstration Test (TCDT) activities. The TCDT provides the crew with emergency egress training, opportunities to inspect their mission payloads in the orbiter's payload bay, and simulated countdown exercises. Also participating are Pilot Scott J. Kelly, and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland, with the European Space Agency, and Jean-Frangois Clervoy of France, also with the European Space Agency. The mission, to service the Hubble Space Telescope, is targeted for launch Dec. 6 at 2:37 a.m. EST aboard Space Shuttle Discovery.

  15. STS-103 Commander Brown arrives at KSC for launch

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Commander Curtis L. Brown Jr. smiles on his arrival at the Shuttle Landing Facility aboard a T-38 jet aircraft. He joins other crew members Pilot Scott J. Kelly and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland and Jean-Frangois Clervoy of France, for pre-launch preparations on mission STS-103 aboard Space Shuttle Discovery. Nicollier and Clervoy are with the European Space Agency. The mission, to service the Hubble Space Telescope, is scheduled for launch Dec. 11 at 12:13 a.m. EST from Launch Pad 39B. Discovery is expected to land at KSC Monday, Dec. 20, at 9:21 p.m. EST.

  16. Development of helium refrigeration/ liquefaction system at BARC, India

    NASA Astrophysics Data System (ADS)

    Ansari, N. A.; Goyal, M.; Chakravarty, A.; Menon, Rajendran S.; Jadhav, M.; Rane Nair, T., Sr.; Kumar, J.; Kumar, N.; Bharti, SK; Chakravarty, Abhilash; Jain, A.; Joemon, V.

    2017-02-01

    An experimental helium refrigerator/liquefier, using ultra high speed cryogenic turboexpanders, is designed and developed at Cryo-Technology Division, BARC. The developed system is based on the modified Claude cycle. The developed system is presently fully functional consisting of process compressor with gas management system, coldbox, helium receiver Dewar, tri-axial transfer line and helium recovery system. Extended trial runs are conducted to evaluate the performance of the developed system. During these trials, liquefaction rate of around 32 l/hr and refrigeration capacity of around 190W is achieved. The paper addresses design, development and commissioning aspects of the developed helium liquefier along with results of performance evaluation trial runs.

  17. Official portrait of the STS-46 Atlantis, Orbiter Vehicle (OV) 104, crew

    NASA Technical Reports Server (NTRS)

    1992-01-01

    The crewmembers assigned to NASA's STS-46 mission pose with seven flags that represent participation on the flight. Commander Loren J. Shriver (right), holding launch and entry helmet (LEH), and Pilot Andrew M. Allen (left), also holding LEH, are seated in the front. Standing behind them and wearing launch and entry suits (LESs) are (left to right) Mission Specialist (MS) Marsha S. Ivins, MS Claude Nicollier (representing the European Space Agency (ESA)), MS and Payload Commander (PLC) Jeffrey A. Hoffman, MS Franklin R. Chang-Diaz, and Payload Specialist Franco Malerba (flying for the Italian Space Agency (ASI)). The flags (left to right) represent the United States of America (USA), Costa Rica (Chang-Diaz's native country), Italy, Switzerland (Nicollier's homeland), NASA, ESA, and ASI. Portrait made by NASA JSC photographer Robert L. Walck.

  18. A glass half full: the dubious history of elder abuse policy.

    PubMed

    Teaster, Pamela B; Wangmo, Tenzin; Anetzberger, Georgia J

    2010-01-01

    This article highlights the brief 30-year history of major U.S. policies that address elder abuse. The history of elder abuse policy is checkered and incomplete, reflecting a lack of comprehensive federal legislation. We begin our review by discussing the scope of elder abuse policy and, in particular, the Social Security Block Grant, which has become the sole source of federal aid for Adult Protective Services programs. The other source of federal aid, typically for helping efforts by Area Agencies on Aging, is the Older Americans Act. We document the incremental but increasing attention paid to elder abuse by chronicling key initiatives, including early congressional reports and hearings; White House Conferences on Aging; and efforts by pioneers such as Mario Biaggi, Claude Pepper, John Breaux, and Orin Hatch-efforts that we believe have led to the various introductions of the Elder Justice Act.

  19. New Study Finds Increasing Gender Equity at U.S. Research Institutions

    NASA Astrophysics Data System (ADS)

    Showstack, Randy

    2009-06-01

    Women and men faculty in science, engineering, and mathematics for the most part have comparable opportunities within major U.S. research universities, according to a report released 2 June by the U.S. National Research Council (NRC). The report found that gender does not appear to have been a factor in a number of important career transitions and outcomes, including hiring for tenure track and tenure positions and promotions. “That is probably going to be surprising to many people. It was surprising to our own panel. And it may not have been the case if we had done the study in 1985 instead of 2005,” said Claude Canizares, cochair of the NRC committee that prepared the report, entitled Gender Differences at Critical Transitions in the Careers of Science, Engineering and Mathematics Faculty.

  20. Nonlinear Cochlear Signal Processing and Phoneme Perception

    NASA Astrophysics Data System (ADS)

    Allen, Jont B.; Régnier, Marion; Phatak, Sandeep; Li, Feipeng

    2009-02-01

    The most important communication signal is human speech. It is helpful to think of speech communication in terms of Claude Shannon's information theory channel model. When thus viewed, it immediately becomes clear that the most complex part of speech communication channel is in auditory system (the receiver). In my opinion, even after years of work, relatively little is know about how the human auditory system decodes speech. Given cochlear damaged, speech scores are greatly reduced, even with tiny amounts of noise. The exact reasons for this SNR-loss presently remain unclear, but I speculate that the source of this must be cochlear outer hair cell temporal processing, not central processing. Specifically, "temporal edge enhancement" of the speech signal and forward masking could easily be modified in such ears, leading to SNR-Loss. What ever the reason, SNR-Loss is the key problem that needs to be fully researched.

  1. STS-61 crewmembers training with the Remote Manipulator System

    NASA Technical Reports Server (NTRS)

    1993-01-01

    The Remote Manipulator System (RMS) eases a mannequin representing an astronaut into position for an STS-61 Hubble Space Telescope (HST) servicing task in the Space Shuttle mockup and integration laboratory at JSC (35699, 35703); Wide-angle view of the RMS easing a mannequin into position for work on the HST mock-up in bldg 9N (35700-1); Swiss scientist Claude Nicollier, mission specialist, works the control of the RMS during a training session in the manipulator development facility (MDF) in JSC's Shuttle mock-up and integration laboratory. Astronaut Kenneth D. Bowersox (left), pilot, is among the other crewmembers in training for the STS-61 HST servicing mission (35702).

  2. Mission Specialist Smith is suited and ready for launch

    NASA Technical Reports Server (NTRS)

    1999-01-01

    In the Operations and Checkout Building, STS-103 Mission Specialist Steven L. Smith signals he is suited up and ready for launch. Other crew members are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly and Mission Specialists C. Michel Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Jean-Frangois Clervoy of France and Claude Nicollier of Switzerland. Clervoy and Nicollier are with the European Space Agency. The STS-103 mission, to service the Hubble Space Telescope, is scheduled for launch Dec. 17 at 8:47 p.m. EST from Launch Pad 39B. Mission objectives include replacing gyroscopes and an old computer, installing another solid state recorder, and replacing damaged insulation in the telescope. After the 8-day, 21-hour mission, Discovery is expected to land at KSC Sunday, Dec. 26, at about 6:30 p.m. EST.

  3. Mendelevium: The Way It Was

    ScienceCinema

    None

    2016-07-12

    A reel of black & white film shot nearly 60 years ago has surfaced at Berkeley Lab, depicting the discovery of Mendelevium - or Element 101 - as reenacted by some of the legendary scientists who did the actual work at that time. Since the 1940s, Berkeley Lab scientists were locked in a race to synthesize new elements, and more often than not, they came out winners. Sixteen elements, most of them in the actinide series at the bottom of the periodic table, were discovered and synthesized by its researchers. Retired Berkeley Lab physicist Claude Lyneis found the reel in a box of dusty and deteriorating films slated for disposal. Using digital editing skills he acquired to make videos of his son's lacrosse team, Lyneis has produced and narrated an excerpt of this nearly-lost footage. It is an entertaining and informative look at the pioneering physics performed at UC Berkeley and Lawrence Berkeley National Laboratory's hillside campus.

  4. Beautiful Surfaces. Style and Substance in Florentius Schuyl's Illustrations for Descartes' Treatise on Man.

    PubMed

    Chan, Eleanor

    2016-01-01

    The assumption that the Cartesian bête-machine is the invention of René Descartes (1596-1650) is rarely contested. Close examination of Descartes' texts proves that this is a concept founded not on the basis of his own writings, but a subsequent critical interpretation, which developed and began to dominate his work after his death. Descartes' Treatise on Man, published posthumously in two rival editions, Florentius Schuyl's Latin translation De Homine (1662), and Claude Clerselier's Traité de l'homme, has proved particularly problematic. The surviving manuscript copies of the Treatise on Man left no illustrations, leaving both editors the daunting task of producing a set of images to accompany and clarify the fragmented text. In this intriguing case, the images can be seen to have spoken louder than the text which they illustrated. This paper assesses Schuyl's choice to represent Descartes' Man in a highly stylized manner, without superimposing Clerselier's intentions onto De Homine.

  5. Electronic ordering and disorder effects in the pseudogap state of YBa2Cu3Oy

    NASA Astrophysics Data System (ADS)

    Julien, Marc-Henri

    2014-03-01

    We report NMR measurements in the normal state of underdoped YBa2Cu3Oy. While unambiguous indication of charge-density-wave ordering is found in the pseudogap state, we interpret this as short range CDW order nucleated around native defects. We discuss the connections of this result to the initial evidence of CDW order in YBa2Cu3Oy from NMR in high magnetic fields, to the more recent X-ray scattering data in the normal state as well as to a wider body of experimental results which have been considered to characterize the pseudogap state. Work performed in collaboration with Tao Wu, Hadrien Mayaffre, Steffen Krämer, Mladen Horvatic & Claude Berthier (LNCMI), Ruixing Liang, Walter N. Hardy and Douglas A. Bonn (UBC).

  6. Messier, Copernicus, Flamsteed: The SAF Rare-Book Collection in Paris

    NASA Astrophysics Data System (ADS)

    Pasachoff, Jay M.

    2014-01-01

    The historic books belonging to the Société Astronomique de France, founded by Camille Flammarion in 1887, are located partly in Paris and partly at the Flammarion site in Juvisy, a Paris suburb. Their holdings include first editions of Copernicus's De Revolutionibus and of Flamsteed's star atlas, as well as Messier's own copy of his 1783 and 1784 papers with his handwritten comments and additions. I will describe the fruitless search for a Bevis atlas and the circumstances that led me to inspect these treasures. I thank David Valls-Gabaud and Philippe Morel of the Société Astronomique de France for their hospitality in Paris, Jean-Claude Pecker, and Owen Gingerich for his prior work on Messier's catalogue.

  7. [Agustín Moreno: scientific psychology and women's legal responsibility in Spain].

    PubMed

    Bandrés, Javier; Llavona, Rafael

    2011-11-01

    Agustín Moreno Rodríguez (1886-1967) studied Medicine and Natural Sciences at the Central University of Spain, in Madrid. He was a student of Dr. Luis Simarro, the University's professor of Experimental Psychology and of Tomas Maestre, the University's professor of Medical Law, Toxicology and Psychiatry. In 1910, he published the text The woman's civil and penal responsibility during the menstrual period. In this work, he approaches the question of the legal responsibility of women, based on the principle of excitation/reaction of Claude Bernard and on his personal version of the concept of iteration elaborated by Luis Simarro. Dr. Moreno also defends the thesis that menstruation adds some uniqueness to the function of the feminine psyche and, therefore, modifies the responsibility of a woman's actions. We also comment on the predominant approach to the mind of women in the Spanish scientific psychology of that time and the reaction of the Spanish feminist intellectuals.

  8. A Tutorial on Analog Computation: Computing Functions over the Reals

    NASA Astrophysics Data System (ADS)

    Campagnolo, Manuel Lameiras

    The best known programmable analog computing device is the differential analyser. The concept for the device dates back to Lord Kelvin and his brother James Thomson in 1876, and was constructed in 1932 at MIT under the supervision of Vannevar Bush. The MIT differential analyser used wheel-and-disk mechanical integrators and was able to solve sixth-order differential equations. During the 1930’s, more powerful differential analysers were built. In 1941 Claude Shannon showed that given a sufficient numbers of integrators the machines could, in theory, precisely generate the solutions of all differentially algebraic equations. Shannon’s mathematical model of the differential analyser is known as the GPAC.

  9. [Three Copt mummies of Antinoe in Lyon].

    PubMed

    Fischer, Louis Paul

    2006-01-01

    Three mummies--one of a woman and two of a woman and a child--are nowadays presented in the Museum of Anatomy Testut-Latarjet in Lyon. They have been brought in 1901 from Egypt to the Museum Guimet of Lyon and after a few years, they have been given to Professor Testut and studied by Louis Paul Fisher and Frederique Cantero in a thesis of medicine of Lyon (1991). They have been examined by x-rays non-invasive scanning by Professor Michel Bochut. Finally Professor Jean-Claude Goyon, chairman in the "Maison de l'Orient", proposed to date them from the end of the 5th or the beginning of the 6th century, after the designs and the ornaments of the clothes.

  10. Information theory in systems biology. Part II: protein-protein interaction and signaling networks.

    PubMed

    Mousavian, Zaynab; Díaz, José; Masoudi-Nejad, Ali

    2016-03-01

    By the development of information theory in 1948 by Claude Shannon to address the problems in the field of data storage and data communication over (noisy) communication channel, it has been successfully applied in many other research areas such as bioinformatics and systems biology. In this manuscript, we attempt to review some of the existing literatures in systems biology, which are using the information theory measures in their calculations. As we have reviewed most of the existing information-theoretic methods in gene regulatory and metabolic networks in the first part of the review, so in the second part of our study, the application of information theory in other types of biological networks including protein-protein interaction and signaling networks will be surveyed.

  11. Information theory in systems biology. Part I: Gene regulatory and metabolic networks.

    PubMed

    Mousavian, Zaynab; Kavousi, Kaveh; Masoudi-Nejad, Ali

    2016-03-01

    "A Mathematical Theory of Communication", was published in 1948 by Claude Shannon to establish a framework that is now known as information theory. In recent decades, information theory has gained much attention in the area of systems biology. The aim of this paper is to provide a systematic review of those contributions that have applied information theory in inferring or understanding of biological systems. Based on the type of system components and the interactions between them, we classify the biological systems into 4 main classes: gene regulatory, metabolic, protein-protein interaction and signaling networks. In the first part of this review, we attempt to introduce most of the existing studies on two types of biological networks, including gene regulatory and metabolic networks, which are founded on the concepts of information theory.

  12. The STS-103 crew address family and friends at Pad 39B

    NASA Technical Reports Server (NTRS)

    1999-01-01

    The STS-103 crew address family and friends at Launch Pad 39B. From left to right are Pilot Scott J. Kelly, Commander Curtis L. Brown Jr., and Mission Specialists C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Jean-Frangois Clervoy of France , Claude Nicollier of Switzerland and Steven L. Smith. Nicollier and Clervoy are with the European Space Agency. In the background is Space Shuttle Discovery, alongside the lighted Fixed Service Structure. The STS-103 mission, to service the Hubble Space Telescope, is scheduled for launch Dec. 17 at 8:47 p.m. EST from Launch Pad 39B. Mission objectives include replacing gyroscopes and an old computer, installing another solid state recorder, and replacing damaged insulation in the telescope. The mission is expected to last about 8 days and 21 hours. Discovery is expected to land at KSC Sunday, Dec. 26, at about 6:25 p.m. EST.

  13. STS-103 MS Nicollier prepares to enter orbiter from White Room

    NASA Technical Reports Server (NTRS)

    1999-01-01

    STS-103 Mission Specialist Claude Nicollier, in his orange launch and entry suit, shakes hands with NASA Quality Assurance Specialist Danny Wyatt in the White Room before entering the orbiter. Other closeout crew members are United Space Alliance (USA) Suit Technician Ray Cuevas (left) and USA Orbiter Vehicle Closeout Chief Travis Thompson. The White Room is an environmental chamber at the end of the orbiter access arm on the fixed service structure. It provides entry to the orbiter crew compartment. The mission, to service the Hubble Space Telescope, is scheduled to lift off at 7:50 p.m. EST Dec. 19 on mission STS-103, servicing the Hubble Space Telescope. Objectives for the nearly eight-day mission include replacing gyroscopes and an old computer, installing another solid state recorder, and replacing damaged insulation in the telescope. Discovery is expected to land at KSC Monday, Dec. 27, at about 5:24 p.m. EST.

  14. STS-103 Mission Specialist Grunsfeld suits up before launch.

    NASA Technical Reports Server (NTRS)

    1999-01-01

    After donning his launch and entry suit, STS-103 Mission Specialist John M. Grunsfeld (Ph.D.) signals he's ready for the second launch attempt of Space Shuttle Discovery. The previous launch attempt on Dec. 17 was scrubbed about 8:52 p.m. due to numerous violations of weather launch commit criteria at KSC. Grunsfeld and other crew members Commander Curtis L. Brown Jr., Pilot Scott J. Kelly and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), Claude Nicollier of Switzerland and Jean-Francois Clervoy of France are scheduled to lift off at 7:50 p.m. EST Dec. 19 on mission STS-103, servicing the Hubble Space Telescope. Objectives for the nearly eight-day mission include replacing gyroscopes and an old computer, installing another solid state recorder, and replacing damaged insulation in the telescope. Discovery is expected to land at KSC Monday, Dec. 27, at about 5:24 p.m. EST.

  15. STS-103 Pilot Kelly suits up before launch.

    NASA Technical Reports Server (NTRS)

    1999-01-01

    STS-103 Pilot Scott J. Kelly is suited up and ready for the second launch attempt of Space Shuttle Discovery. The previous launch attempt on Dec. 17 was scrubbed about 8:52 p.m. due to numerous violations of weather launch commit criteria at KSC. Kelly and fellow crew members Commander Curtis L. Brown Jr. and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland and Jean-Francois Clervoy of France are scheduled to lift off at 7:50 p.m. EST Dec. 19 on mission STS-103, servicing the Hubble Space Telescope. Objectives for the nearly eight-day mission include replacing gyroscopes and an old computer, installing another solid state recorder, and replacing damaged insulation in the telescope. Discovery is expected to land at KSC Monday, Dec. 27, at about 5:24 p.m. EST.

  16. An introduction to the medical epistemology of Georges Canguilhem: moving beyond Michel Foucault.

    PubMed

    Spicker, S F

    1987-11-01

    Although American philosophers and physicians are generally familiar with the writings of Claude Bernard (1813-1878), especially his Introduction to the Study of Experimental Medicine (1865), the medical epistemology of Georges Canguilhem, born in 1904, is virtually unknown in English speaking nations. Although indebted to Bernard for his conception of the methods to be employed in the acquisition of medical knowledge, Canguilhem radically reformulates Bernard's concepts of 'disease', 'health', 'illness', and 'pathology'. Contemporary exhortations to medical professionals and medical students that they "pay more attention to the whole patient" take on significance in working through the writings of Canguilhem; of crucial importance is the relation that obtains between a patient's unique symptomatology and the proper drug regiment that is required.

  17. [A brief history of the anatomy and physiology of a mysterious and hidden gland called the pancreas].

    PubMed

    Navarro, Salvador

    2014-11-01

    Because of its retrogastric location and appearance, which is similar to mesenteric fat, for centuries the pancreas has been a mysterious, hidden organ that has received little attention. However, its importance was intuited and described by Herophilus, Ruphos of Ephesus and Galen. This gland began to appearin distinct medical treatises from the 16th century. There are two important scientists in the history of the pancreas. The fist, Johann Georg Wirsung, described the main pancreatic duct in 1642, a date considered by many to be the start of Pancreatology. The second, Claude Bernard, described pancreatic exocrine function between 1849 and 1856 and is considered the father of pancreatic physiology. Besides these two outstanding figures, there is a constellation of personalities who contributed to improving knowledge of this enigmatic gland with the results of their studies. The aim of this article is to call attention to some of the most notable findings that have enhanced knowledge of this gland over the years.

  18. Bruner's Search for Meaning: A Conversation between Psychology and Anthropology

    PubMed Central

    Mattingly, Cheryl; Lutkehaus, Nancy C.; Throop, C. Jason

    2010-01-01

    We introduce a special issue of Ethos devoted to the work of Jerome Bruner and his careerlong attempts to seek innovative ways to foster a dialogue between psychology and anthropology. The articles in this special issue situate Bruner's meaning-centered approach to psychology and his groundbreaking work on narrative in the broader context of the developmental trajectory of both of fields of inquiry. Bruner's work has been enormously influential in the subfields of cultural psychology and psychological anthropology, especially because of his important contributions to our understanding of the intimate relationship between culture and mind. We examine Bruner's past and ongoing engagement with such luminary figures as Lev Vygotsky, Jean Piaget, Alfred Kroeber, Claude Lévi-Strauss, and Clifford Geertz to highlight points of convergence and tension between his version of cultural psychology and contemporary theorizing and practice in psychological anthropology. We also review his practical and theoretical contributions to the fields of medicine, law, and education. PMID:20706551

  19. List of participants at SIDE IV meeting, Tokyo, 27 November--1 December 2000

    NASA Astrophysics Data System (ADS)

    2001-12-01

    Mark J Ablowitz, Vsevolod Adler, Mark Alber, Said Belmehdi, Marco Boiti, Claude Brezinski, R Bullough, Y M Chiang, Theodore Chihara, Peter A Clarkson, Robert Conte, Adam Doliwa, Vladimir Dorodnitsyn, Mitsuaki Eguchi, Claire Gilson, Basil Grammaticos, Valeri Gromak, Rod Halburd, Koji Hasegawa, Jarmo Hietarinta, Ryogo Hirota, Xing Biao Hu, M Idzumi, J Inoguchi, Hiroya Ishikara, Mourad Ismail, Shin Isojima, Kenichi Ito, Yoshiaki Itoh, Masashi Iwasaki, Klara Janglajew, Michio Jimbo, Nalini Joshi, Kenji Kajiwara, Saburo Kakei, Masaru Kamata, Satoshi Kamei, Rinat Kashaev, Shingo Kawai, Taeko Kimijima, K Kimura, Anatol Kirillov, Koichi Kondo, Boris Konopelchenko, Martin Kruskal, Atsuo Kuniba, Wataru Kunishima, Franklin Lambert, Serguei Leble, Decio Levi, Shigeru Maeda, Manuel Manas, Ken-Ichi Maruno, Tetsu Masuda, J Matsukidaira, Atsushi Matsumiya, Shigeki Matsutani, Yukitaka Minesaki, Mikio Murata, Micheline Musette, Atsushi Nagai, Katsuya Nakagawa, Atsushi Nakamula, Akira Nakamura, Yoshimasa Nakamura, Frank Nijhoff, J J C Nimmo, Katsuhiro Nishinari, Michitomo Nishizawa, A Nobe, Masatoshi Noumi, Yaeko Ohsaki, Yasuhiro Ohta, Kazuo Okamoto, Alexandre Orlov, Naoki Osada, Flora Pempinelli, Spiro Pyrlis, Reinout Quispel, Orlando Ragnisco, Alfred Ramani, Jean-Pierre Ramis, Andreas Ruffing, Simon Ruijsenaars, Satoru Saito, Noriko Saitoh, Hidetaka Sakai, Paulo Santini, Narimasa Sasa, Ryu Sasaki, Yoshikatsu Sasaki, Junkichi Satsuma, Sergei Sergeev, Nobuhiko Shinzawa, Evgueni Sklyanin, Juris Suris, Norio Suzuki, Yukiko Tagami, Katsuaki Takahashi, Daisuke Takahashi, Tomoyuki Takenawa, Yoshiro Takeyama, K M Tamizhmani, T Tamizhmani, Kouichi Toda, Morikatsu Toda, Tetsuji Tokihiro, Takayuki Tsuchida, Yohei Tsuchiya, Teruhisa Tsuda, Satoru Tsujimoto, Walter Van Assche, Claude Viallet, Luc Vinet, Shinsuke Watanabe, Yoshihida Watanabe, Ralph Willox, Pavel Winternitz, Yasuhiko Yamada, Yuji Yamada, Jin Yoneda, Haruo Yoshida, Katsuhiko Yoshida, Daisuke Yoshihara, Fumitaka Yura, J

  20. [Neurologic manifestations of infectious endocarditis].

    PubMed

    Hannachi, N; Béard, T; Ben Ismail, M

    1991-01-01

    Thirty out of 287 patients (10.4%) admitted to hospital for infective endocarditis between December 1970 and January 1990 had neurological complications. Twenty-three patients had native valve infectious endocarditis and 7 had prosthetic valve endocarditis. The clinical features were characterized by the frequency of aortic valve involvement (23 out of 30) and other complications, especially cardiac failure (16 cases) and peripheral vascular manifestations (7 cases). The commonest organism was the staphylococcus (53% of identified organisms) but the number of negative blood cultures was high (50% of cases). The neurological complication was often the presenting symptom of the endocarditis (19 cases) but it occurred after bacteriological cure in 4 cases. The complications observed were cerebral ischemia (16 cases), cerebral haemorrhage (11 cases), coma (2 cases), and one peripheral neuropathy causing a Claude Bernard Horner syndrome. These complications presented with hemiplegia in 17 cases, a meningeal syndrome in 8 cases, a convulsion in 1 case, a Von Wallenberg syndrome in 1 case, and a Claude Bernard Horner syndrome in 1 case. Twelve patients had a transient or permanent neurological coma. Cerebral CT scan showed ischemic lesions in 7 cases and haemorrhagic lesions in 10 cases. Carotid angiography demonstrated mycotic aneurysms in 6 patients. Twelve patients died: the cause of death was neurological coma (7 cases), low cardiac output (4 cases) and haemorrhagic shock (1 case). Four patients underwent neurosurgery: 3 for clipping a mycotic aneurysm and 1 for drainage of an intracerebral haematoma. Poor prognostic factors were: coma, cardiac failure, cardiac valve prosthesis and, above all, the extent and multiplicity of the neurological lesions. The authors propose the following measures to improve the prognosis: early surgery in cases of large and/or mobile vegetations especially when the infecting organism is a staphylococcus and when a systemic embolism has

  1. Feasibility study of a nation-wide Early Warning System: the application of the EEW software PRESTo on the Italian Strong Motion Network (RAN)

    NASA Astrophysics Data System (ADS)

    Zollo, Aldo; Picozzi, Matteo; Elia, Luca; Martino, Claudio; Brondi, Piero; Colombelli, Simona; Emolo, Antonio; Festa, Gaetano; Marcucci, Sandro

    2014-05-01

    The past two decades have witnessed a huge progress in the development, implementation and testing of Earthquakes Early Warning Systems (EEWS) worldwide, as the result of a joint effort of the seismological and earthquake engineering communities to set up robust and efficient methodologies for the real-time seismic risk mitigation. The leading experience of the operational early warning system implemented by the Japan Meteorological Agency showed the effectiveness of a combined onsite and network-based approach to rapidly broadcast the rapid warning after a potential damaging earthquake. At the nation-wide scale, the Japanese system makes use of real-time data streamed by the extremely dense accelerograph array (about 1000 seismic instruments) deployed across Japan. With more than 750 accelerometric stations installed over all the active seismic zones, target cities and strategic infrastructures, Italy has the potential for a nation-wide early warning system, although the communication network and data sharing must be expanded and improved. A significant number of these stations are nodes of the RAN (Italian Accelerometric Network) managed by the Italian national emergency management department (Dipartimento della Protezione Civile, DPC), whose data are used for emergency response services. In the framework of the REAKT-Strategies and tools for Real Time Earthquake RisK ReducTion FP7 European project, the AMRA-RISSCLab group is engaged in a feasibility study on the implementation of the EEW software PRESTo earthquake early warning platforms on the Italian accelerometric network (RAN) PRESTo (PRobabilistic and Evolutionary early warning SysTem) is a highly configurable and easily portable platform for Earthquake Early Warning. The system processes the live accelerometric streams from the stations of a seismic network to promptly provide probabilistic and evolutionary estimates of location and magnitude of detected earthquakes while they are occurring, as well as

  2. Demographische Entwicklung in der Metropolregion Berlin-Brandenburg

    NASA Astrophysics Data System (ADS)

    Beyer, Wolf; Bluth, Friedrich

    〝Denn eins ist sicher: Die Rente.`` Der vielzitierte Satz des früheren Arbeits- und Sozialministers Norbert Blüm klingt heute vielen wie Hohn. Der Altersaufbau der deutschen Bevölkerung erinnert grafisch immer mehr an einen Baum auf dünnem Stämmchen als an eine Pyramide. Angesichts dessen rücken demographische Entwicklungen mehr und mehr in den Fokus der Öffentlichkeit. Besonders die neuen Bundesländer sind massiv von Abwanderung und einem nie dagewesenen Geburtenrückgang betroffen.DIPL.-GEOGR. UTE C. BAUERsprach mitFRIEDRICH BLUTHundWOLF BEYERüber die Besonderheiten der demographischen Prozesse in Berlin und Brandenburg. Beyer leitete bis Anfang 2004 das brandenburgische Referat für Raumbeobachtung. Seine Aufgabe bestand darin, Planungsgrundlagen für die Gemeinsame Landesplanung Berlin-Brandenburg(GL) zu schaffen. Dazu zählen auch Bevölkerungsprognosen für die Kreise und Städte Brandenburgs. Bluth ist in der Senatsverwaltung für Stadtentwicklung Berlin beschäftigt und leitet dort die Gruppe 〝Stadtwissen, Stadtentwicklungsmonitoring, Bevölkerungsprognose.``

  3. Figurational dynamics and parliamentary discourses of living standards in Ireland.

    PubMed

    Dolan, Paddy

    2009-12-01

    While the concept of living standards remains central to political debate, it has become marginal in sociological research compared to the burgeoning attention given to the topic of consumer culture in recent decades. However, they both concern how one does and should consume, and, indeed, behave at particular times. I use the theories of Norbert Elias to explain the unplanned but structured (ordered) changes in expected standards of living over time. This figurational approach is compared to other alternative explanations, particularly those advanced by Bourdieu, Veblen and Baudrillard. Though these offer some parallels with Elias's theories, I argue that consumption standards are produced and transformed through the changing dependencies and power relations between social classes. They cannot be reduced to the intentions, interests or ambitions of particular elites, nor to the needs of social systems. Using qualitative data from parliamentary debates in Ireland to trace changing norms and ideals of consumption, as well as historical data to reconstruct shifts in social interdependencies, I further contend that discourses of living standards and luxury are vital aspects of the growing identification and empathy between classes, which in turn encourages greater global integration in the face of emigration and national decline.

  4. The new science and the public sphere in the premodern era.

    PubMed

    Rupp, J C

    1995-01-01

    This paper argues that the New Science, which was seen as essentially a public enterprise, was moreover a major constituent of the public sphere in early modern era. In seventeenth- and eighteenth-century Western Europe the sphere of public experimentation, testing, and discussion related to the new science, manifested itself as a highly diversified, contested, and complex social field. Two general problems arose in constructing this cultural public sphere: the selection of participants in the debate and the inclusion of a heterogenous public in the experimental scene. National authorities employed diverse policies but none denied the necessity of public debate for testing the validity of experimentations. The public sphere had to create its own conditions of existence by imposing manifold regulations in order to make these public meetings possible and enjoyable. The regulations emphasized common interest and the moral code as the most basic condition for the sustenance of the public sphere, thus enhancing self-restraint, tolerance, and politeness on the part of both discussants and participants. The more inclusive and heterogenous the public sphere, the more these norms were required. Thus the sphere of public debate constituted by early modern science implied a civilizing process, quite different from and more encompassing than the one analyzed by Norbert Elias.

  5. The barbarism of civilization: cultural genocide and the 'stolen generations'.

    PubMed

    van Krieken, R

    1999-06-01

    Norbert Elias suggested that 'civilization' involves the transformation of human habitus so that violence of all sorts is gradually subjected to greater and more sophisticated forms of management and control, whereas 'decivilization' encompasses processes which produce an increase in violence and a breakdown in the stability and consistency of on-going social relations. What remains unexplored is the extent to which 'civilizing offensives', the self-conscious attempts to bring about 'civilization', have revolved around essentially violent policies and practices. This paper examines the systematic removal of indigenous Australian children from their families, largely for the social engineering purpose of the gradual and systematic annihilation of Aboriginal cultural identity. At the time, these policies and practices were constructed by most observers as contributing to the 'welfare' of Australian Aborigines, and this intersection of welfare and violence raises the possibility that civilization and decivilization, rather than being different processes which may or may not run alongside each other, interpenetrate each other so that, under certain circumstances, societies are 'barbaric' precisely in their movement towards increasing civilization. It may also be possible to describe the move away from the systematic removal of Aboriginal children since the 1970s as itself part of a civilizing process, an increasing recognition of the human rights of Australian Aborigines and of the inhumanity of those policies and practices. The paper concludes by addressing the implications for theories of civilization and decivilization, as well as more generally for our contemporary understanding of what it means to be a 'civilized' modern citizen.

  6. Credit and civilization.

    PubMed

    Newton, Tim

    2003-09-01

    This paper analyses financial credit in order to re-examine the work of Norbert Elias, particularly his association of interdependency complexity with social discipline, and his approach to contradiction. Following a discussion of these issues, the paper examines Elias's writing on money and explores the emergence of financial credit networks in early modern England. Attention is paid to credit networks and social discipline, to credit and the state, and to the contradictory images associated with the transition to modern cash economies. From one perspective, early modern credit networks might be read as a confirmation of Elias, particularly his argument that interdependency complexity, changing power balances and self-restraint are interwoven. Yet the development of modern cash money raises questions, not just in relation to Elias's treatment of money, but also with regard to his assumptions about social discipline and his approach to ambivalence and contradiction. Drawing on the foregoing discussion, the paper argues that the relation between interdependency complexity and social discipline is contingent and variable, and that interdependency complexity may simultaneously encourage contradictory processes, such as those of civilizing and barbarity.

  7. The ontological status of western science and medicine

    PubMed Central

    Hankey, Alex

    2012-01-01

    This paper traces the revolutionary changes that have transformed the ontological status of western physics and biology over the last thirty years, so as to show in detail how they have moved towards the perspective of the Vedic sciences. From this it appears that Ayurveda's more holistic approach is no longer in opposition to the views of physics and biology. In physics, experimental verification of phenomena associated with quantum correlations have forced scientists to accept that the macroscopic world is not strongly objective: traditional western scientific ontology stands rejected. One consequence is that the world is not necessarily reductionist i.e. based solely on the properties of its tiniest constituents. In biology, the 1930's discovery of homeostasis has reached a natural climax: the feedback instabilities, identified by Norbert Wiener as inevitably accompanying control processes, are now recognized to be states of optimal regulation, where organisms centre their function. The non-reductive properties of these states clearly distinguish the theory of control from previous physical theories; they now occupy the centre-stage of life. Possibly against expectation, their non-reductive nature makes their physics holistic: western biology seems to have broken free of reductionist physics. When Ayurveda and bioscience are compared in light of these little appreciated advances in fundamental science, the supposed differences between them are vastly reduced – they practically dissolve. Instead of being poles apart, the ontologies of western science and Ayurveda seem to have become almost identical. PMID:23125507

  8. Gregory Bateson and the mathematicians: from interdisciplinary interaction to societal functions.

    PubMed

    Heims, S P

    1977-04-01

    An instance of fruitful cross-disciplinary contacts is examined in detail. The ideas involved include (1) the double-blind hypothesis for schizophrenia, (2) the critique of game theory from the viewpoint of anthropology and psychiatry, and (3) the application of concepts of communication theory and theory of logical types to an interpretation of psychoanalytic practice. The protagonists of the interchange are Gregory Bateson and the two mathematicians Norbert Wiener and John von Neumann; the date, March 1946. This interchange and its sequels are described. While the interchanges between Bateson and Wiener were fruitful, those between Bateson and von Neumann were much less so. The latter two held conflicting premises concerning what is significant in science; Bateson's and Wiener's were compatible. In 1946, Wiener suggested that information and communication might be appropriate central concepts for psychoanalytic theory--a vague general idea which Bateson (with Ruesch) related to contemporary clinical practice. For Bateson, Wiener, and von Neumann, the cross-disciplinary interactions foreshadowed a shift in activities and new roles in society, to which the post World War II period was conducive. Von Neumann became a high-level government advisor; Wiener, an interpreter of science and technology for the general public; and Bateson a counter-culture figure.

  9. Quantum Error Correction: Optimal, Robust, or Adaptive? Or, Where is The Quantum Flyball Governor?

    NASA Astrophysics Data System (ADS)

    Kosut, Robert; Grace, Matthew

    2012-02-01

    In The Human Use of Human Beings: Cybernetics and Society (1950), Norbert Wiener introduces feedback control in this way: ``This control of a machine on the basis of its actual performance rather than its expected performance is known as feedback ... It is the function of control ... to produce a temporary and local reversal of the normal direction of entropy.'' The classic classroom example of feedback control is the all-mechanical flyball governor used by James Watt in the 18th century to regulate the speed of rotating steam engines. What is it that is so compelling about this apparatus? First, it is easy to understand how it regulates the speed of a rotating steam engine. Secondly, and perhaps more importantly, it is a part of the device itself. A naive observer would not distinguish this mechanical piece from all the rest. So it is natural to ask, where is the all-quantum device which is self regulating, ie, the Quantum Flyball Governor? Is the goal of quantum error correction (QEC) to design such a device? Devloping the computational and mathematical tools to design this device is the topic of this talk.

  10. Transcending disciplines: Scientific styles in studies of the brain in mid-twentieth century America.

    PubMed

    Abraham, Tara H

    2012-06-01

    Much scholarship in the history of cybernetics has focused on the far-reaching cultural dimensions of the movement. What has garnered less attention are efforts by cyberneticians such as Warren McCulloch and Norbert Wiener to transform scientific practice in an array of disciplines in the biomedical sciences, and the complex ways these efforts were received by members of traditional disciplines. In a quest for scientific unity that had a decidedly imperialistic flavour, cyberneticians sought to apply practices common in the exact sciences-mainly theoretical modeling-to problems in disciplines that were traditionally defined by highly empirical practices, such as neurophysiology and neuroanatomy. Their efforts were met with mixed, often critical responses. This paper attempts to make sense of such dynamics by exploring the notion of a scientific style and its usefulness in accounting for the contrasts in scientific practice in brain research and in cybernetics during the 1940s. Focusing on two key institutional contexts of brain research and the role of the Rockefeller and Macy Foundations in directing brain research and cybernetics, the paper argues that the conflicts between these fields were not simply about experiment vs. theory but turned more closely on the questions that defined each area and the language used to elaborate answers.

  11. Nurses' daily life: gender relations from the time spent in hospital1

    PubMed Central

    Pereira, Audrey Vidal

    2015-01-01

    Objective: to analyze the everyday life of nurses through the sexual work division as well as through interdependence relations and the time in hospital. Method: quanti-qualitative study, based on the Time Use Survey and in Norbert Elias's Configuration Theory of Interdependencies. Daily shifts distribution record, directed by 42 participants - with self-confrontation - by interviews which drew dialogues on subjective aspects of the everyday experiences related to use of time, based on a job at a university hospital. The theoretical intake that founded data analysis was based on concepts of conflicts of interest, power struggles, sexual work division and polychronic-monochronic concepts - whether the work environment demands multitasking nurses or not. Results: time records allowed to observe differences between the groups studied, useful to identify conflicts, tensions, power struggles and gender inequalities in interviewees' everyday affairs that do not only affect physical and mental health, but also their way of life. Conclusion: the analytical path pointed out the need for public policies that promote equity in gender relations, keeping at sight the exercise of plural discourses and tolerant stances capable to respect differences between individual and collective time. PMID:26487146

  12. Modulation theory, dispersive shock waves and Gerald Beresford Whitham

    NASA Astrophysics Data System (ADS)

    Minzoni, A. A.; Smyth, Noel F.

    2016-10-01

    Gerald Beresford (GB) Whitham, FRS, (13th December, 1927-26th January, 2014) was one of the leading applied mathematicians of the twentieth century whose work over forty years had a profound, formative impact on research on wave motion across a broad range of areas. Many of the ideas and techniques he developed have now become the standard tools used to analyse and understand wave motion, as the papers of this special issue of Physica D testify. Many of the techniques pioneered by GB Whitham have spread beyond wave propagation into other applied mathematics areas, such as reaction-diffusion, and even into theoretical physics and pure mathematics, in which Whitham modulation theory is an active area of research. GB Whitham's classic textbook Linear and Nonlinear Waves, published in 1974, is still the standard reference for the applied mathematics of wave motion. In honour of his scientific achievements, GB Whitham was elected a Fellow of the American Academy of Arts and Sciences in 1959 and a Fellow of the Royal Society in 1965. He was awarded the Norbert Wiener Prize for Applied Mathematics in 1980.

  13. Zeit im Wandel der Zeit.

    NASA Astrophysics Data System (ADS)

    Aichelburg, P. C.

    Contents: Einleitung(P. C. Aichelburg). 1. Über Zeit, Bewegung und Veränderung (Aristoteles). 2. Ewigkeit und Zeit (Plotin). 3. Was ist die Zeit? (Augustinus). 4. Von der Zeit (Immanuel Kant). 5. Newtons Ansichten über Zeit, Raum und Bewegung (Ernst Mach). 6. Über die mechanische Erklärung irreversibler Vorgänge (Ludwig Boltzmann). 7. Das Maß der Zeit (Henri Poincaré). 8. Dauer und Intuition (Henri Bergson). 9. Die Geschichte des Unendlichkeitsproblems (Bertrand Russell). 10. Raum und Zeit (Hermann Minkowski). 11. Der Unterschied von Zeit und Raum (Hans Reichenbach). 12. Newtonscher und Bergsonscher Zeitbegriff (Norbert Wiener). 13. Die Bildung des Zeitbegriffs beim Kinde (JeanPiaget).14. Eine Bemerkung über die Beziehungen zwischen Relativitätstheorie und der idealistischen Philosophie (Kurt Gödel). 15. Der zweite Hauptsatz und der Unterschied von Vergangenheit und Zukunft (Carl Friedrich v. Weizsäcker). 16. Zeit als physikalischer Begriff (Friedrich Hund). 17. Zeitmessung und Zeitbegriff in der Astronomie (Otto Heckmann). 18. Kann die Zeit rückwärts gehen? (Martin Gardner). 19. Zeit und Zeiten (Ilya Prigogine, Isabelle Stengers). 20. Zeit als dynamische Größe in der Relativitätstheorie (P. C. Aichelburg).

  14. MO-FG-213-04: Managing the Relationship

    SciTech Connect

    Wong, J.

    2015-06-15

    Research Contracts – a Primer [Norbert Pelc; Stanford University] What topics are suited to industrial grants vs. academic grants How do resources (personnel effort, tuition) get allocated and charged in academia What are reasonable resource and timeline requests for small and big projects; from small and big companies “Fair market value” considerations Sections of a research agreement (IP including software confidential information, publications, data, exclusivity, support) 4. Managing the relationship [John Wong, Johns Hopkins University] How to effectively collaborate with each other How to adapt to changes in the relationship How to renew funding with the industry Moderated Panel Discussion [All speakers + moderators] Learning Objectives: 1. Understand the motivations of each partner 2. Elements that contribute to a successful partnership 3. Avoiding pitfalls - Challenges on either side that may derail a project 4. How to frame a research grant and agreement 5. How to sustain the collaborative relationship Amit Sawant: Funding from: NIH. Varian, Elekta and VisionRT; Michelle Svatos: Employee and shareholder: Varian, Board Member, TopasMC; Kevin Brown: Employee, Elekta; T. Rock Mackie: Consultant, Accuray; Norbert Pelc: Research support: Philips Healthcare, GE Healthcare; John Wong: Funding from NIH, Xstrahl and Elekta. Co-founder and advisor for JPLC Associates, LLC.

  15. Design and Success of a 21st Century Cancer Education Program at the University of Louisville.

    PubMed

    Hein, David W; Kidd, La Creis R

    2016-07-30

    Cancer incidence, morbidity, and mortality in the Commonwealth of Kentucky are among the highest in the nation. The University of Louisville was the recipient of a National Cancer Institute (NCI)-funded cancer education program grant in 1975 under the leadership of Dr. Norbert Burzynski. A new and totally redesigned performance-based University of Louisville Cancer Education Program was funded by NCI in 2011 to recruit and motivate outstanding undergraduate and health professional students to pursue further training and careers in cancer research. Here, we describe the strategy, design, methods, implementation, and accomplishments of our twenty-first century performance-based cancer education program. Our program will meet or exceed all of its 5-year performance goals, including the total number students (n = 156) and under-represented minorities (n = 53) who successfully completed the program under the mentorship of cancer research-intensive faculty members of the James Graham Brown Cancer Center (JGBCC). The mentored research program is complemented with professional development and enhancement activities, including cancer research seminars presented by faculty members actively engaged in research centered on the diagnosis, treatment or prevention of cancer, creation of individual career development plans, exploration of cancer research careers, and acquisition of professionalism skills. Student interests towards cancer research significantly increased after completion of the program compared to baseline (P = 0.02). Based on quantitative and qualitative analysis of various components of the curricula, the trainees favor practical, engaging, and interactive activities aligned within professional career goals and objectives. For instance, the trainees prefer two 30-min small group discussions on "Navigating Careers in Cancer Research" with faculty, professional students, and program alumni. Future updates to the program include new activities that

  16. Signal processing with neural networks: throwing off the yoke of linearity

    NASA Astrophysics Data System (ADS)

    Hecht-Nielsen, Robert

    1991-11-01

    During the 1930s and 1940s Norbert Wiener and others invented the core concepts of linear signal processing. These ideas quickly became popular and played a significant role in the Allies' victory in World War II. During and after the war, linear signal processing theory was greatly expanded and began to take on the character of an imposing monolith. By the mid- 1940s, Wiener (and others, such as Dennis Gabor) came to recognize that linear signal processing theory, while interesting and very useful, was only a piece of a much larger picture. In 1946 and 1958 Gabor and Wiener, respectively, attempted to address the whole picture. While they were not completely successful, they did implicitly set an agenda for a more general approach to signal processing. Although a few others have, from time to time, addressed this agenda; in terms of the signal processing community as a whole it still remains lost in the shadow of the ever-growing monolith of linear signal processing theory. The thesis of this paper is that it is now time to get on with the Wiener and Gabor agenda. It is time to make general signal processing the mainstream focus of the subject. It is argued here that the best way to do this is to abandon the transfer function/Fourier analysis/z-transform approach of the current linear signal processing regime and replace it with a much more natural intellectual framework for general signal processing--the framework offered by neurocomputing. A potential benefit of this refocusing of the field is that the detailed engineering might soon be left to machines, while human technologists will be able to concentrate on the art of signal sculpting.

  17. Water security and societal impacts of tropical cyclones in northwestern Mexico, 1970-2010

    NASA Astrophysics Data System (ADS)

    Scott, C. A.; Farfan, L.

    2012-12-01

    Mexico.Norbert Impacts in Alamos, Sonora, 12 Oct. 2008

  18. On small things in water moving around: Purcell's contributions to biology

    NASA Astrophysics Data System (ADS)

    Berg, Howard

    2012-02-01

    I went to see Purcell after finishing my course work for the Ph.D. (1961) to ask whether I might join his group. ``But I don't have any graduate students,`` he said. ``Why is that?'' I asked. ``I can't think of anything to do,'' he replied. That was a wipe out. After I had finished my Ph.D. with Ramsey on the hydrogen maser (1964), Ed and I came up with an idea that led to work on sedimentation field-flow fractionation (PNAS 1967). We had hoped this method would be useful for biology, but problems of adsorption of proteins to surfaces stood in the way. Then I moved over to the biology department and got interested in the motile behavior of bacteria (1968). Here was a subject that I thought Ed would really enjoy. There were wonderful movies made by Norbert Pfennig of experiments done by Theodor Engelmann in the 1880's. We found a 16-mm projector and looked at these movies on Ed's office wall. Ed's first comment proved seminal, ''How can such a small cell swim in a straight line?'' We thought about how cells count molecules in their environment and wrote ``Physics of chemoreception,'' (Biophys. J.,1977). In the meantime, Ed gave a memorable lecture at Viki Weisskopf's retirement symposium, his classic ``Life at low Reynolds number'' (Am. J. Phys. 1977). Ed really wanted to understand what it would be like to swim like a bacterium! He wasn't very interested in what the literature had to say about such a problem, he wanted to think it through for himself. My role was straight man. I very much enjoyed the ride.

  19. Interrelationships between information and energy using knowledge management tools

    SciTech Connect

    Lizcano, D. E-mail: mariaaurora.martinez@udima.es; Martínez, A. María E-mail: mariaaurora.martinez@udima.es

    2014-10-06

    Edward Fredkin was an enthusiastic advocate of information-based theoretical physics, who, in the early 1980s, proposed a new theory of physics based on the idea that the universe is ultimately composed of software. According to Fredkin, reality should be considered as being composed not of particles, matter and forces or energy but of bits of data or information modified according to computational rules. Fredkin went on to demonstrate that, while energy is necessary for storing and retrieving information, it can be arbitrarily reduced in order to carry out any particular instance of information processing, and this operation does not have a lower bound. This implies that it is information rather than matter or energy that should be considered at the ultimate fundamental constituent of reality. This possibility had already been suggested by other scientists. Norbert Wiener heralded a fundamental shift from energy to information and suggested that the universe was founded essentially on the transformation of information, not energy. However, Konrad Zuse was the first, back in 1967, to defend the idea that a digital computer is computing the universe. Richard P. Feynman showed this possibility in a similar light in his reflections on how information related to matter and energy. Other pioneering research on the theory of digital physics was published by Kantor in 1977 and more recently by Stephen Wolfram in 2002, who thereby joined the host of voices upholding that it is patterns of information, not matter and energy, that constitute the cornerstones of reality. In this paper, we introduce the use of knowledge management tools for the purpose of analysing this topic.

  20. Galileo In-Situ Dust Measurements and the Physics of Jupiter's Gossamer Rings

    NASA Astrophysics Data System (ADS)

    Krueger, H.; Hamilton, D. P.; Moissl, R.; Gruen, E.

    2007-12-01

    During its late orbital mission about Jupiter, the Galileo spacecraft flew twice through the giant planet's gossamer ring system. The dusty ring material is produced when interplanetary impactors collide with embedded moonlets. Optical images imply that the rings are constrained both horizontally and vertically by the orbits of the moons Amalthea and Thebe with the exception of a faint outward protrusion called the Thebe Extension. During the ring passages, the Galileo impact-ionization dust detector counted a few thousand impacts but only about 100 complete data sets of dust impacts (i.e. impact time, impact speed, mass, impact direction, etc.) were successfully transmitted to Earth. The instrument verified the outward extension of the gossamer ring beyond Thebe's orbit and measured a major reduction in particle ring material interior to Thebe's orbit. The existence of this partially evacuated gap in ring material is also indirectly confirmed by Galileo in-situ energetic particle measurements (Norbert Krupp, priv. comm.). Detected particle sizes range from about 0.2 to 4 micron, extending the size distribution by an order of magnitude towards smaller particles than previously derived from optical imaging (Showalter et al., Icarus 2007). The grain size distribution increases towards smaller grains, showing a much higher proportion of small particles in the Amalthea gossamer ring than in the Thebe ring and the Thebe Extension. Our analysis shows that particles contributing most to the optical cross-section are about 4 micron in radius, in agreement with imaging results. Finally, Galileo also detected some micron and sub-micron grains on highly inclined orbits with inclinations up to 20 degrees. Recent modelling (Hamilton & Krueger, Nature, submitted) shows that time variable electromagnetic effects can account for all of these surprising results. In particular, when the ring particles travel through Jupiter's shadow, dust grain electric charges vary systematically

  1. Interrelationships between information and energy using knowledge management tools

    NASA Astrophysics Data System (ADS)

    Lizcano, D.; Martínez, A. María

    2014-10-01

    Edward Fredkin was an enthusiastic advocate of information-based theoretical physics, who, in the early 1980s, proposed a new theory of physics based on the idea that the universe is ultimately composed of software. According to Fredkin, reality should be considered as being composed not of particles, matter and forces or energy but of bits of data or information modified according to computational rules. Fredkin went on to demonstrate that, while energy is necessary for storing and retrieving information, it can be arbitrarily reduced in order to carry out any particular instance of information processing, and this operation does not have a lower bound. This implies that it is information rather than matter or energy that should be considered at the ultimate fundamental constituent of reality. This possibility had already been suggested by other scientists. Norbert Wiener heralded a fundamental shift from energy to information and suggested that the universe was founded essentially on the transformation of information, not energy. However, Konrad Zuse was the first, back in 1967, to defend the idea that a digital computer is computing the universe. Richard P. Feynman showed this possibility in a similar light in his reflections on how information related to matter and energy. Other pioneering research on the theory of digital physics was published by Kantor in 1977 and more recently by Stephen Wolfram in 2002, who thereby joined the host of voices upholding that it is patterns of information, not matter and energy, that constitute the cornerstones of reality. In this paper, we introduce the use of knowledge management tools for the purpose of analysing this topic.

  2. Radio Telescopes Reveal Youngest Stellar Corpse

    NASA Astrophysics Data System (ADS)

    2004-06-01

    Astronomers using a global combination of radio telescopes to study a stellar explosion some 30 million light-years from Earth have likely discovered either the youngest black hole or the youngest neutron star known in the Universe. Their discovery also marks the first time that a black hole or neutron star has been found associated with a supernova that has been seen to explode since the invention of the telescope nearly 400 years ago. M51 An artist's impression of Supernova 1986J. The newly discovered nebula around the black hole or neutron star in the center is shown in blue, and is in the center of the expanding, fragmented shell of material thrown off in the supernova explosion, which is shown in red. CREDIT: Norbert Bartel and Michael F. Bietenholz, York University; Artist: G. Arguner (Click on image for larger version) Image Files Artist's Conception (above image, 836K) Galaxy and Supernova (47K) A VLA image (left) of the galaxy NGC 891, showing the bright supernova explosion below the galaxy's center. At right, a closer view of the supernova, made with a global array of radio telescopes. CREDIT: Miguel A. Perez-Torres, Antxon Alberdi and Lucas Lara, Instituto de Astrofisica de Andalucia - CSIC, Spain, Jon Marcaide and Jose C. Guirado, Universidad de Valencia, Spain Franco Mantovani, IRA-CNR, Italy, Eduardo Ros, MPIfR, Germany, and Kurt W. Weiler, Naval Research Laboratory, USA Multi-Frequency Closeup View (201K) Blue and white area shows the nebula surrounding the black hole or neutron star lurking in the center of the supernova. This nebula is apparent at a higher radio frequency (15 GHz). The red and also the contours show the distorted, expanding shell of material thrown off in the supernova explosion. This shell is seen at a lower radio frequency (5 GHz). CREDIT: Michael F. Bietenholz and Norbert Bartel, York University, Michael Rupen, NRAO, NRAO/AUI/NSF A supernova is the explosion of a massive star after it exhausts its supply of nuclear fuel and

  3. [Ethical principles in human scientific research].

    PubMed

    Cruz-Coke, R

    1994-07-01

    Hippocrates was the first physician to use the scientific method to find rational and not religious or mythic causes, for the etiology of diseases. Hippocrates and Aristoteles did not dare to dissect the human body. Afterwards however, many scientists such as Herophilus, Erasitastrus, Vesalus and Fallopio, performed experiments in human beings using vivisection. According to that age's ideas, there was no cruelty in performing vivisection in criminals, since useful knowledge for the progress of medicine and relief of diseases was obtained. Only during the nineteenth century and with Claude Bernard (1865), the ethical principles of systematic scientific research in humans were defined. These principles were violated by nazi physicians during Hitler's dictatorship in Germany (1933-1945). As a response to these horrors, the Ethical Codes of Nuremberg (1947) and Geneva (1948), that reestablished all the strength of Hippocratic principles, were dictated. The Nuremberg rules enact that a research subject must give a voluntary consent, that the experiment must by necessary and exempt of death risk, that the research must be qualified and that the experiment must be discontinued if there is a risk for the subject. The Geneva statement is a modernized hippocratic oath that protects patient's life above all. These classical rules, in force at the present time, are the essential guides that must be applied by physicians and researchers.

  4. Neuromuscular block

    PubMed Central

    Bowman, W C

    2006-01-01

    Descriptions of the South American arrow poisons known as curares were reported by explorers in the 16th century, and their site of action in producing neuromuscular block was determined by Claude Bernard in the mid-19th century. Tubocurarine, the most important curare alkaloid, played a large part in experiments to determine the role of acetylcholine in neuromuscular transmission, but it was not until after 1943 that neuromuscular blocking drugs became established as muscle relaxants for use during surgical anaesthesia. Tubocurarine causes a number of unwanted effects, and there have been many attempts to replace it. The available drugs fall into two main categories: the depolarising blocking drugs and the nondepolarising blocking drugs. The former act by complex mixed actions and are now obsolete with the exception of suxamethonium, the rapid onset and brief duration of action of which remain useful for intubation at the start of surgical anaesthesia. The nondepolarising blocking drugs are reversible acetylcholine receptor antagonists. The main ones are the atracurium group, which possess a built-in self-destruct mechanism that makes them especially useful in kidney or liver failure, and the vecuronium group, which are especially free from unwanted side effects. Of this latter group, the compound rocuronium is of especial interest because its rapid onset of action allows it to be used for intubation, and there is promise that its duration of action may be rapidly terminated by a novel antagonist, a particular cyclodextrin, that chelates the drug, thereby removing it from the acetylcholine receptors. PMID:16402115

  5. The physiological role of cardiac cytoskeleton and its alterations in heart failure.

    PubMed

    Sequeira, Vasco; Nijenkamp, Louise L A M; Regan, Jessica A; van der Velden, Jolanda

    2014-02-01

    Cardiac muscle cells are equipped with specialized biochemical machineries for the rapid generation of force and movement central to the work generated by the heart. During each heart beat cardiac muscle cells perceive and experience changes in length and load, which reflect one of the fundamental principles of physiology known as the Frank-Starling law of the heart. Cardiac muscle cells are unique mechanical stretch sensors that allow the heart to increase cardiac output, and adjust it to new physiological and pathological situations. In the present review we discuss the mechano-sensory role of the cytoskeletal proteins with respect to their tight interaction with the sarcolemma and extracellular matrix. The role of contractile thick and thin filament proteins, the elastic protein titin, and their anchorage at the Z-disc and M-band, with associated proteins are reviewed in physiologic and pathologic conditions leading to heart failure. This article is part of a Special Issue entitled: Reciprocal influences between cell cytoskeleton and membrane channels, receptors and transporters. Guest Editor: Jean Claude Hervé

  6. Exploring molecular biology. An older surgeon looks at a new universe.

    PubMed

    Smith, M P

    1995-08-01

    The rapidity and the magnitude of progress in molecular biology slipped by many of us practicing surgeons. Although articles about molecular medicine appear regularly in our surgical literature, for many of us, their content is rather mysterious. The articles often end with a glossary, because most readers do not understand the language. In November 1993, the entire issue of the Archives of Surgery was devoted to molecular medicine. In an editorial, Claude Organ, Jr, MD, a member of this association, encouraged the surgeon to "cohabit" with the molecular scientist. Many university departments of surgery have professors who are both surgeons and molecular biologists. Ed Passaro, MD, also a member of this association, observed in 1992 that most surgeons had overlooked this new field and needed to learn about it to play a role in applying it to clinical medicine. That means knowing what new tests and treatments are available and how to apply them. It means being able to counsel patients. Also, it is important for knowledgeable surgeons to serve on the regular hospital committees that will oversee these new tests and treatments, and to offer their unique judgment in assessing risk, reward, and ethical implications.

  7. STS-103 crew take part in CEIT

    NASA Technical Reports Server (NTRS)

    1999-01-01

    In the Payload Hazardous Servicing Facility, members of the STS-103 crew look at some of the equipment to be used during their mission. The seven-member crew are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland, and Jean-Frangois Clervoy of France. Nicollier and Clervoy are with the European Space Agency. Mission STS-103 is a 'call-up' due to the need to replace portions of the pointing system, the gyros, which have begun to fail on the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. The gyroscopes allow the telescope to point at stars, galaxies and planets. The STS-103 crew will not only replace gyroscopes, it will also replace a Fine Guidance Sensor and an older computer with a new enhanced model, an older data tape recorder with a solid state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. The scheduled launch date in October is under review.

  8. Developing a quality assurance program for online services.

    PubMed

    Humphries, A W; Naisawald, G V

    1991-07-01

    A quality assurance (QA) program provides not only a mechanism for establishing training and competency standards, but also a method for continuously monitoring current service practices to correct shortcomings. The typical QA cycle includes these basic steps: select subject for review, establish measurable standards, evaluate existing services using the standards, identify problems, implement solutions, and reevaluate services. The Claude Moore Health Sciences Library (CMHSL) developed a quality assurance program for online services designed to evaluate services against specific criteria identified by research studies as being important to customer satisfaction. These criteria include reliability, responsiveness, approachability, communication, and physical factors. The application of these criteria to the library's existing online services in the quality review process is discussed with specific examples of the problems identified in each service area, as well as the solutions implemented to correct deficiencies. The application of the QA cycle to an online services program serves as a model of possible interventions. The use of QA principles to enhance online service quality can be extended to other library service areas.

  9. Twenty Years of Delila and Molecular Information Theory

    PubMed Central

    Schneider, Thomas D.

    2007-01-01

    A brief personal history is given about how information theory can be applied to binding sites of genetic control molecules on nucleic acids. The primary example used is ribosome binding sites in Escherichia coli. Once the sites are aligned, the information needed to describe the sites can be computed using Claude Shannon’s method. This is displayed by a computer graphic called a sequence logo. The logo represents an average binding site, and the mathematics easily allows one to determine the components of this average. That is, given a set of binding sites, the information for individual binding sites can also be computed. One can go further and predict the information of sites that are not in the original data set. Information theory also allows one to model the flexibility of ribosome binding sites, and this led us to a simple model for ribosome translational initiation in which the molecular components fit together only when the ribosome is at a good ribosome binding site. Since information theory is general, the same mathematics applies to human splice junctions, where we can predict the effect of sequence changes that cause human genetic diseases and cancer. The second example given is the Pribnow ‘box’ which, when viewed by the information theory method, reveals a mechanism for initiation of both transcription and DNA replication. Replication, transcription, splicing, and translation into protein represent the central dogma, so these examples show how molecular information theory is contributing to our knowledge of basic biology. PMID:18084638

  10. STS-42 Preflight Background Briefing Life Sciences (MSFC)

    NASA Technical Reports Server (NTRS)

    1992-01-01

    A panel of scientists give an overview of the experiments that are to take place on-board the STS-42 Discovery mission. Ronald J. White, International Microgravity Laboratory (IML) Program Scientist, gives a general description of why going into space with IML is so important. Robert Snyder, IML Mission Scientist, describes other aspects of the microgravity environment. Millard Reschke, Principal Investigator (PI) Microgravity Vestibular Investigation (MVI), explains what MVI is and the effects of space on the vestibular system. David Heathcote, PI for the Gravitational Plant Physiology Facility (GPPF), describes the GPPF's on-board experiment involving the effects of light and gravity on plants. Claude Brillouet, Program Scientist of the Biorack Facility, gives an overview of the Biorack equipment and experiment. Alan Mortimer, Chief Life Sciences for the Canadian Space Agency (CSA), describes the on-board experiments for the long- and short-term effects of microgravity on humans and biotechnology (cell separation techniques). The men then answer questions from the press and NASA centers.

  11. STS-103 crew take part in CEIT

    NASA Technical Reports Server (NTRS)

    1999-01-01

    During a Crew Equipment Interface Test, STS-103 Commander Curtis L. Brown Jr. (left) and Pilot Scott J. Kelly look at a replacement computer for the Hubble Space Telescope. The payload hardware is in the Payload Hazardous Servicing Facility. Other members of the crew are Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland, and Jean-Frangois Clervoy of France. Nicollier and Clervoy are with the European Space Agency. Mission STS-103 is a 'call-up' due to the need to replace portions of the pointing system, the gyros, which have begun to fail on the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. The gyroscopes allow the telescope to point at stars, galaxies and planets. The STS-103 crew will not only replace gyroscopes, it will also replace a Fine Guidance Sensor and an older computer with the new enhanced model, an older data tape recorder with a solid state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. The scheduled launch date in October is under review.

  12. [Xavier Bichat's Medical Thought in the Historical Context of French Vitalism].

    PubMed

    Hwang, Suyoung

    2012-04-30

    The French vitalism is different from vitalism in general. It is a position of some physiologists who worked from the end of the 18th century to the early days of the 19th century, defending the peculiarity of life phenomena in contrast to the Cartesian theory of the animal-machine. Its main representatives are Paul-Joseph Barthez and Theophile de Bordeu, who belonged to the vitalist school of Montpellier. They argue, in contrast to mechanism, that life involves a special principle and cannot be explained in terms of physical and chemical properties alone. Marie Francois Xavier Bichat (1771-1802), inheriting this position, endeavored to establish physiology as a science which cannot be reduced to the physical sciences. He was also the first to introduce the notion of tissues as distinct entities. The aim of his concept of physiology is to explain the whole of life phenomena through the ultimate properties of tissues, that is, through sensibility and contractility. After Bichat, Francois Magendie inherited his experimental concepts, but critiqued his vitalism. Claude Bernard, known as the founder of experimental physiology, was influenced considerably by Bichat's idea of physiology. Through the notion of tissues, he unites zoology, botany and medicine in the domain of general physiology. Additionally, his concept of "milieu interieur" results from his study of Bichat's physiology, particularly from the concept of the "natural type".

  13. Linear and nonlinear dynamics of liquid planetary cores

    NASA Astrophysics Data System (ADS)

    Lathrop, D. P.

    2013-12-01

    This is the 50th anniversary of Ed Lorenz brilliant paper "Deterministic Nonperiodic Flow.'' Lorenz's work, along with many other founders' efforts, gave rise to the study of nonlinear dynamics. That field has allowed us to move beyond simple linear characterizations of nature, and to open up a deeper understanding of the Earth, other planets, and stars. Of the many things that make the Earth a habitable home, one is the existence of a planetary magnetic field generated in our liquid iron outer core. The generation process is known to be strongly nonlinear, and thereby almost certainly turbulent. Yet it is not a simple homogeneous isotropic turbulent flow, but is instead heavily modified by rotation and magnetic forces. We attempt to better understand the Earth's core using a three-meter liquid sodium laboratory model of the core. Our work in sodium in this system has just begun. The system exhibits a variety of behaviors with at least twelve different states, drawing different amounts of power, and causing varying levels of magnetic field amplification. In some states, rotation and magnetic fields cause the dynamics to simplify relative to more general turbulent flows in comparable conditions. Acknowledgements: I gratefully acknowledge my collaborators Daniel Zimmerman, Santiago Triana, Donald Martin, Nolan Balew, Henri-Claude Nataf, and Barbara Brawn-Cinani, and funding from the National Science Foundation Earth Sciences Instrumentation and Geophysics programs.

  14. Determinism and probability in the development of the cell theory.

    PubMed

    Duchesneau, François

    2012-09-01

    A return to Claude Bernard's original use of the concept of 'determinism' displays the fact that natural laws were presumed to rule over all natural processes. In a more restricted sense, the term boiled down to a mere presupposition of constant determinant causes for those processes, leaving aside any particular ontological principle, even stochastic. The history of the cell theory until around 1900 was dominated by a twofold conception of determinant causes. Along a reductionist trend, cells' structures and processes were supposed to be accounted for through their analysis into detailed partial mechanisms. But a more holistic approach tended to subsume those analytic means and the mechanism involved under a program of global functional determinations. When mitotic and meiotic sequences in nuclear replication were being unveiled and that neo-Mendelian genetics was being grafted onto cytology and embryology, a conception of strict determinism at the nuclear level, principally represented by Wilhelm Roux and August Weismann, would seem to rule unilaterally over the mosaic interpretation of the cleavage of blastomeres. But, as shown by E.B. Wilson, in developmental processes there occur contingent outcomes of cell division which observations and experiments reveal. This induces the need to admit 'epigenetic' determinants and relativize the presumed 'preformation' of thedevelopmental phases by making room for an emergent order which the accidental circumstances of gene replication would trigger on.

  15. The discovery and rediscovery of oxygen.

    PubMed

    Sternbach, George L; Varon, Joseph

    2005-02-01

    The therapeutic use of oxygen was pioneered in the early 20(th) century by the respiratory physiologist John Scott Haldane. His work followed Claude Bernard's description of the toxic effects of carbon monoxide. Haldane, having also observed the effects of carbon monoxide poisoning, became aware of the therapeutic benefits of oxygen in this condition. He was also an advocate of oxygen as a therapeutic agent in other respiratory illness, and made efforts to define how the gas could best be administered. The history of identification of oxygen as a chemical element is convoluted. In the 17(th) century, the controversial John Mayow suggested that only a portion of air was necessary for sustaining life. Mayow's work was largely overlooked during his lifetime, and his insight was subsequently eclipsed by the phlogiston theory, an erroneous concept widely believed for nearly a century after his death. This theory was ultimately disproved by Joseph Priestley in 1774. Although the point of primacy is somewhat contentious, Priestley shares the distinction of discovering elemental oxygen with Antoine-Laurent Lavoisier, the French chemist, and Carl Wilhelm Scheele, the Swedish apothecary.

  16. From the philosophy auditorium to the neurophysiology laboratory and back: from Bergson to Damasio.

    PubMed

    Blumen, Sergiu C; Blumen, Nava

    2002-03-01

    Henri Bergson (1859-1941) was probably the most influential French philosopher at the turn of the twentieth century. In 1927 he was awarded the Nobel Prize for literature. Far beyond the restricted academic philosophical milieu, the impact of his thinking reached personalities as diverse as Claude Debussy, Marcel Proust, George Bemard Shaw, and the impressionists. His essay The Laughter (Le Rire) is one of the most profound and original ever written on the sense of humor. Bergson's opinions, with their emphasis on life, instinct and intuition, represented a deviation from the rationalist mainstream of western philosophical tradition. In some circles he was received with skepticism and irony, as in Bertrand Russel's History of Western Philosophy. Today, unbiased by theoretical "bergsonism," neurophysiologic research--as undertaken mainly by Antonio Damasio's team at Iowa University--confirms many of his hypotheses and elucidates their mechanisms. In this new light, intuition and "recognition by the body" should not be seen as the personal fantasy of an original thinker but as fundamental cognitive tools.

  17. [Present data on influenza virus isolated from ducks and chickens, and influenza virus C. Anti-influenza drugs].

    PubMed

    Fernández del Campo, José Antonio Cabezas

    2004-01-01

    Present data on influenza virus isolated from ducks and chickens, and influenza virus C. Anti-influenza drugs. Within the broad field of Glycopathology and Glycotherapeutics, research on influenza virus types A, B and C from humans and several bird species (particularly migratory birds such as ducks, since they are reservoirs for viruses), as well as the search for improved drugs designed for the prevention or treatment of epidemics/pandemics produced by most of those viruses are issues of relevant interest not only from a scientific point of view but also for repercussions on health and the important economical consequences. The research work begun by the author and collaborators at the Department of Biochemistry and Molecular Biology of the University of Salamanca (Spain) in the middle of the 1970's, developed later in close cooperation with the "(Unité d'Ecologie Virale" of the Pasteur Institute of Paris (Prof. Claude Hannoun and collaborators), has been published in about twenty papers that mainly focus on the theoretic-experimental study of: The sialidase (neuraminidase) activity of human influenza viruses types A and B. The acetylesterase activity of type C virus from humans and dogs. The sialidase activity of type A virus from ducks and pigs, in comparison with that of humans. Certain sialidase inhibitors as useful anti-influenza drugs, especially in the case of possible future influenza pandemics of avian origin.

  18. The XIIIth International Physiological Congress in Boston in 1929: American physiology comes of age.

    PubMed

    Rall, Jack A

    2016-03-01

    In the 19th century, the concept of experimental physiology originated in France with Claude Bernard, evolved in Germany stimulated by the teaching of Carl Ludwig, and later spread to Britain and then to the United States. The goal was to develop a physicochemical understanding of physiological phenomena. The first International Physiological Congress occurred in 1889 in Switzerland with an emphasis on experimental demonstrations. The XIIIth Congress, the first to be held outside of Europe, took place in Boston, MA, in 1929. It was a watershed meeting and indicated that American physiology had come of age. Meticulously organized, it was the largest congress to date, with over 1,200 participants from more than 40 countries. Getting to the congress was a cultural adventure, especially for the 400 scientists and their families from over 20 European countries, who sailed for 10 days on the S.S. Minnekahda. Many of the great physiologists of the world were in attendance, including 22 scientists who were either or would become Nobel Laureates. There were hundreds of platform presentations and many experimental demonstrations. The meeting was not without controversy as a conflict, still not completely settled, arose over the discovery of ATP. After the meeting, hundreds of participants made a memorable trip to the Marine Biological Laboratory at Woods Hole, MA, which culminated in a "good old fashioned Cape Cod Clambake." Although not as spectacular as the 1929 congress, the physiological congresses have continued with goals similar to those established more than a century ago.

  19. STS-103 crew practices driving personnel carrier, part of TCDT activities

    NASA Technical Reports Server (NTRS)

    1999-01-01

    STS-103 Mission Specialist John M. Grunsfeld (Ph.D.) (far right) practices driving a small armored personnel carrier that is part of emergency egress training during Terminal Countdown Demonstration Test (TCDT) activities. In front is Capt. George Hoggard, trainer with the KSC Fire Department. At far left is Mission Specialist Jean-Frangois Clervoy of France, who is with the European Space Agency. The tracked vehicle could be used by the crew in the event of an emergency at the pad during which the crew must make a quick exit from the area. The TCDT also provides simulated countdown exercises and opportunities to inspect the mission payloads in the orbiter's payload bay. STS-103 is a 'call-up' mission due to the need to replace and repair portions of the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The other STS-103 crew members are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, Steven L. Smith, C. Michael Foale (Ph.D.), (Ph.D.), and Claude Nicollier of Switzerland and Jean-Frangois Clervoy of France, who are with the European Space Agency. The mission is targeted for launch Dec. 6 at 2:37 a.m. EST.

  20. STS-103 crew practices driving personnel carrier during TCDT

    NASA Technical Reports Server (NTRS)

    1999-01-01

    STS-103 Mission Specialist Jean-Frangois Clervoy of France, who is with the European Space Agency, practices driving a small armored personnel carrier that is part of emergency egress training during Terminal Countdown Demonstration Test (TCDT) activities. Riding on the front is Capt. George Hoggard, trainer with the KSC Fire Department. Behind him is Pilot Scott J. Kelly; at right (with earphones) is Mission Specialist Claude Nicollier of Switzerland, who is with the European Space Agency, and at the rear Mission Specialist Steven L. Smith. The tracked vehicle could be used by the crew in the event of an emergency at the pad during which the crew must make a quick exit from the area. The TCDT also provides simulated countdown exercises and opportunities to inspect the mission payloads in the orbiter's payload bay. STS-103 is a 'call-up' mission due to the need to replace and repair portions of the Hubble Space Telescope. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The other STS-103 crew members are Commander Curtis L. Brown Jr. and Mission Specialists C. Michael Foale (Ph.D.) and John M. Grunsfeld (Ph.D.). The mission is targeted for launch Dec. 6 at 2:37 a.m. EST.

  1. STS-103 crew practices driving personnel carrier during TCDT

    NASA Technical Reports Server (NTRS)

    1999-01-01

    During Terminal Countdown Demonstration Test (TCDT) emergency egress training, STS-103 Commander Curtis L. Brown Jr. practices driving a small armored personnel carrier. Riding on the front is Capt. George Hoggard, a trainer with the KSC/CCAS Fire Department. In the carrier behind Brown is (left to right) Pilot Scott J. Kelly and Mission Specialists Steven L. Smith and John M. Grunsfeld (Ph.D.). The tracked vehicle could be used by the crew in the event of an emergency at the pad during which the crew must make a quick exit from the area. The TCDT also provides simulated countdown exercises and opportunities to inspect the mission payloads in the orbiter's payload bay. STS-103 is a 'call-up' mission due to the need to replace and repair portions of the Hubble Space Telescope. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The other STS-103 crew members are Mission Specialists C. Michael Foale (Ph.D.), plus Claude Nicollier of Switzerland and Jean-Frangois Clervoy of France, who are with the European Space Agency. The mission is targeted for launch Dec. 6 at 2:37 a.m. EST.

  2. STS-103 Pilot Scott Kelly during TCDT activities

    NASA Technical Reports Server (NTRS)

    1999-01-01

    STS-103 Pilot Scott J. Kelly is ready to take his turn at driving a small armored personnel carrier that is part of emergency egress training during Terminal Countdown Demonstration Test (TCDT) activities. Behind him (left) is Mission Specialist Jean-Frangois Clervoy of France, who is with the European Space Agency. At right is Mission Specialist Steven L. Smith. The tracked vehicle could be used by the crew in the event of an emergency at the pad during which the crew must make a quick exit from the area. The TCDT also provides simulated countdown exercises and opportunities to inspect the mission payloads in the orbiter's payload bay. STS-103 is a 'call-up' mission due to the need to replace and repair portions of the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The other STS-103 crew members are Commander Curtis L. Brown Jr. and Mission Specialists C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), and Claude Nicollier of Switzerland, who also is with the European Space Agency. The mission is targeted for launch Dec. 6 at 2:37 a.m. EST.

  3. Laws, leaders, and legends of the modern National Library of Medicine

    PubMed Central

    Smith, Kent A.

    2008-01-01

    Purpose: The paper is an expanded version of the 2007 Joseph Leiter National Library of Medicine (NLM)/Medical Library Association Lecture presented at MLA ‘07, the Medical Library Association annual meeting in Philadelphia in May 2007. It presents an historical accounting of four major pieces of legislation, beginning with the NLM Act of 1956 up through the creation of the National Center for Biotechnology Information. Brief Description: The transition from the United States Armed Forces Medical Library to the United States National Library of Medicine in 1956 was a major turning point in NLM's history, scope, and direction. The succeeding landmark legislative achievements—namely, the 1965 Medical Library Assistance Act, the 1968 Joint Resolution forming the Lister Hill National Center for Biomedical Communications, and the 1988 authorization for the National Center for Biotechnology Information— transformed the library into a major biomedical communications institution and a leader and supporter of an effective national network of libraries of medicine. The leaders of the library and its major advocates—including Dr. Michael DeBakey, Senator Lister Hill, and Senator Claude Pepper—together contributed to the creation of the modern NLM. PMID:18379667

  4. Living Together Apart in France and the United States

    PubMed Central

    Martin, Claude; Cherlin, Andrew; Cross-Barnet, Caitlin

    2014-01-01

    Union formation involves a number of stages, as does union dissolution, and new couples often spend an initial period in a non-cohabiting intimate relationship. Yet while certain couples never share the same dwelling, “living apart together”1 has not developed widely as a long-term lifestyle option. Claude Martin in France, and Andrew Cherlin and Caitlin Cross-Barnet in the United States have studied a symmetrical phenomenon, that of couples who continue to live together while considering themselves to be separated. In this article, they draw together their analyses to describe an arrangement which, while marginal, reveals situations where residential separation is not possible, either because of the need to keep up appearances, often for the children’s sake, or because total separation is too frightening or living in separate homes is unaffordable. Beyond the differences between the two countries and the two survey fields, the authors analyse the ways in which persons who “live together apart” describe their loveless relationship that has led to explicit conjugal separation within a shared home. PMID:25170338

  5. [The oldest German textbook on internal medicine of horses, edited at the Kayserlich-Köngliche Pferd-Cur und Operations Schul in Vienna in 1770].

    PubMed

    Greiner, S

    1996-06-01

    The manuscript has the title: "Erkandtnus deren innerlichen Krankheiten des Pferds überhaupt". Through two take downs of the lectures of Ludwig Scotti, the founder of the first school for veterinarians in the German speaking part of Europe and its first teacher, the manuscript is identified as another take down. The first part of the manuscript, which is about internal medicine, in large passages is a literally translation of Lafosse's "Guide de Maréchal". In most passages the second part, which is about pharmacology, is a copy of the German translation of Claude Bourgelat's "Matière médicale" published in 1766. Nevertheless Scotti brings in his own experiences by inserting in or rewriting of some chapters or by adding other theories, likewise his prescriptions cannot be found in Bourgelat's book. The manuscript is an example for the highest level in veterinary science in the second half of the 18th century. This is emphasized through the comparison with contemporary literature in German language, for example the books of von Sind and Deigendesch.

  6. The French Ambassador in Firing Room to watch launch.

    NASA Technical Reports Server (NTRS)

    1999-01-01

    In the Firing Room (left to right) Joseph Rothenberg, associate administrator, Office of Space Flight; JoAnn Morgan, associate director for Advanced Development and Shuttle Upgrades; and Madam de L'Estang and Francois Bujon de L'Estang, ambassador of France, wait for the launch of STS-103. One of the STS-103 crew, Mission Specialist Jean-Francois Clervoy, is from France, and a member of the European Space Agency (ESA). Other crew members are Commander Curtis L. Brown Jr. , Pilot Scott J. Kelly and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.) and Claude Nicollier of Switzerland (also with ESA). The mission, to service the Hubble Space Telescope, is scheduled for launch Dec. 19 at 7:50 p.m. EST from Launch Pad 39B. Mission objectives include replacing gyroscopes and an old computer, installing another solid state recorder, and replacing damaged insulation in the telescope. After the 7-day, 21-hour mission, Discovery is expected to land at KSC Monday, Dec. 27, at about 5:24 p.m. EST.

  7. The French Ambassador in Firing Room to watch launch.

    NASA Technical Reports Server (NTRS)

    1999-01-01

    On hand in the Firing Room to watch the launch of STS-103 are (left to right) Joseph Rothenberg, associate administrator, Office of Space Flight; JoAnn Morgan, associate director for Advanced Development and Shuttle Upgrades; and Francois Bujon de L'Estang, ambassador of France. Behind the ambassador is his wife, Madam de L'Estang. One of the STS-103 crew, Mission Specialist Jean-Francois Clervoy, is from France, and a member of the European Space Agency (ESA). Other crew members are Commander Curtis L. Brown Jr. , Pilot Scott J. Kelly and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.) and Claude Nicollier of Switzerland (also with ESA). The mission, to service the Hubble Space Telescope, is scheduled for launch Dec. 19 at 7:50 p.m. EST from Launch Pad 39B. Mission objectives include replacing gyroscopes and an old computer, installing another solid state recorder, and replacing damaged insulation in the telescope. After the 7-day, 21-hour mission, Discovery is expected to land at KSC Monday, Dec. 27, at about 5:24 p.m. EST

  8. A curious experiment: the paradigm switch from observation and speculation to experimentation, in the understanding of neuromuscular function and disease.

    PubMed

    Pearn, John

    2002-08-01

    The four-link chain of the motor unit represents the contemporary end-point of some two millennia of evolving knowledge in neuroscience. The paradigm shift in neuromuscular epistemology occurred in the mid-17th century. In 1666, the newly graduated Dutch doctor, Jan Swammerdam (1637-1680) published his former investigations of dissected nerve-muscle preparations. These experiments comprised the quantum leap from observation and speculation, to that of experimentation in the field of neuroanatomy and neurophysiology. In what he termed 'A Curious Experiment' he also described the phenomenon of intrinsic muscle excitability - "I cannot observe that the muscle in the living animal ever absolutely ceases from all motion". Eighty years later (1752), von Haller demonstrated experimentally that irritability (contractility) was an intrinsic property of all muscular tissue; and distinguished between the sensibility of nerve impulses and the irritability of muscular contraction. This experimental progression from Swammerdam to von Haller culminated in 1850, when Claude Bernard's studies in experimental pharmacology confirmed that muscle was a functional unit, independent of any electrical innervation via its supplying nerve. This account comprises an audit of Swammerdam's work in the perspective of neuromuscular knowledge.

  9. STS-103 crew take part in CEIT

    NASA Technical Reports Server (NTRS)

    1999-01-01

    In the Payload Hazardous Servicing Facility, members of the STS-103 crew get instructions on use of rib clamps for the Shield Shell Replacement Fabric (SSRF) task on repair of the Hubble Space Telescope. The seven-member crew are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland, and Jean-Frangois Clervoy of France. Nicollier and Clervoy are with the European Space Agency. Mission STS-103 is a 'call-up' due to the need to replace portions of the pointing system, the gyros, which have begun to fail on the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. The gyroscopes allow the telescope to point at stars, galaxies and planets. The STS-103 crew will not only replace gyroscopes, it will also replace a Fine Guidance Sensor, an older computer with a new enhanced model, an older data tape recorder with a solid state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. The scheduled launch date in October is under review.

  10. Cryogenics for the MuCool Test Area (MTA)

    SciTech Connect

    Darve, Christine; Norris, Barry; Pei, Liu-Jin; /Fermilab

    2005-09-01

    MuCool Test Area (MTA) is a complex of buildings at Fermi National Accelerator Laboratory, which are dedicated to operate components of a cooling cell to be used for Muon Collider and Neutrino Factory R&D. The long-term goal of this facility is to test ionization cooling principles by operating a 25-liter liquid hydrogen (LH{sub 2}) absorber embedded in a 5 Tesla superconducting solenoid magnet. The MTA solenoid magnet will be used with RF cavities exposed to a high intensity beam. Cryogens used at the MTA include LHe, LN{sub 2} and LH{sub 2}. The latter dictates stringent system design for hazardous locations. The cryogenic plant is a modified Tevatron refrigerator based on the Claude cycle. The implementation of an in-house refrigerator system and two 300 kilowatt screw compressors is under development. The helium refrigeration capacity is 500 W at 14 K. In addition the MTA solenoid magnet will be batch-filled with LHe every 2 days using the same cryo-plant. This paper reviews cryogenic systems used to support the Muon Collider and Neutrino Factory R&D programs and emphasizes the feasibility of handling cryogenic equipment at MTA in a safe manner.

  11. STS-61 crew utilizing Virtual Reality in training for HST repair mission

    NASA Technical Reports Server (NTRS)

    1993-01-01

    Astronaut Jeffrey A. Hoffman, one of four crewmembers for STS-61 that will conduct scheduled spacewalks during the flight, wears a special helmet and gloves designed to assist in proper positioning near the telescope while on the end of the robot arm. Crewmembers are utilizing a new virtual reality training aid which assists in refining positioning patterns for Space Shuttle Endeavour's Remote Manipulator System (RMS) (36890); Astronaut Claude Nicollier looks at a computer display of the Shuttle's robot arm movements as Thomas D. Akers and Kathryn C. Thornton, mission specialists look on. Nicollier will be responsible for maneuvering the astronauts while they stand in a foot restraint on the end of the RMS arm (36891,36894); Hoffman wears a special helmet and gloves designed to assist in proper positioning near the telescope while on the end of the robot arm (35892); Nicollier looks at a computer display of the Shuttle's robot arm movements as Akers looks on (36893); While (l-r) Astron

  12. CLIC proteins, ezrin, radixin, moesin and the coupling of membranes to the actin cytoskeleton: a smoking gun?

    PubMed

    Jiang, Lele; Phang, Juanita M; Yu, Jiang; Harrop, Stephen J; Sokolova, Anna V; Duff, Anthony P; Wilk, Krystyna E; Alkhamici, Heba; Breit, Samuel N; Valenzuela, Stella M; Brown, Louise J; Curmi, Paul M G

    2014-02-01

    The CLIC proteins are a highly conserved family of metazoan proteins with the unusual ability to adopt both soluble and integral membrane forms. The physiological functions of CLIC proteins may include enzymatic activity in the soluble form and anion channel activity in the integral membrane form. CLIC proteins are associated with the ERM proteins: ezrin, radixin and moesin. ERM proteins act as cross-linkers between membranes and the cortical actin cytoskeleton. Both CLIC and ERM proteins are controlled by Rho family small GTPases. CLIC proteins, ERM and Rho GTPases act in a concerted manner to control active membrane processes including the maintenance of microvillar structures, phagocytosis and vesicle trafficking. All of these processes involve the interaction of membranes with the underlying cortical actin cytoskeleton. The relationships between Rho GTPases, CLIC proteins, ERM proteins and the membrane:actin cytoskeleton interface are reviewed. Speculative models are proposed involving the formation of localised multi-protein complexes on the membrane surface that assemble via multiple weak interactions. This article is part of a Special Issue entitled: Reciprocal influences between cell cytoskeleton and membrane channels, receptors and transporters. Guest Editor: Jean Claude Hervé.

  13. Biochemistry and physiology within the framework of the extended synthesis of evolutionary biology.

    PubMed

    Vianello, Angelo; Passamonti, Sabina

    2016-02-09

    Functional biologists, like Claude Bernard, ask "How?", meaning that they investigate the mechanisms underlying the emergence of biological functions (proximal causes), while evolutionary biologists, like Charles Darwin, asks "Why?", meaning that they search the causes of adaptation, survival and evolution (remote causes). Are these divergent views on what is life? The epistemological role of functional biology (molecular biology, but also biochemistry, physiology, cell biology and so forth) appears essential, for its capacity to identify several mechanisms of natural selection of new characters, individuals and populations. Nevertheless, several issues remain unsolved, such as orphan metabolic activities, i.e., adaptive functions still missing the identification of the underlying genes and proteins, and orphan genes, i.e., genes that bear no signature of evolutionary history, yet provide an organism with improved adaptation to environmental changes. In the framework of the Extended Synthesis, we suggest that the adaptive roles of any known function/structure are reappraised in terms of their capacity to warrant constancy of the internal environment (homeostasis), a concept that encompasses both proximal and remote causes.

  14. Vision loss and hearing loss in painting and musical composition.

    PubMed

    Marmor, Michael F

    2014-07-01

    This article considers the impact of vision and hearing loss on great painters and musical composers. The visual work of Mary Cassatt, Georgia O'Keeffe, Edgar Degas, and Claude Monet all showed alterations as their vision failed. In contrast, Gabriel Fauré, Bedřich Smetana, and Ludwig von Beethoven wrote many of their best compositions while totally deaf, and Georg Friedrich Handel and Frederick Delius struggled to compose late in life when they lost their vision (although their hearing remained excellent). There are 2 major distinctions between the role of vision and hearing for these artistic disciplines. First, there is a surrogate means of "hearing" music, through the musical score, which allows composers to write and edit music while totally deaf. The greatest problem with deafness for a skilled composer is interference from internal noise (tinnitus). There is no surrogate for vision to allow a painter to work when the subject is a blur or the colors on the canvas cannot be distinguished. Second, although the appreciation of art is visual and that of music is auditory, the transcription of both art and musical composition is visual. Thus, visual loss does pose a problem for a composer accustomed to working with good sight, because it disrupts habitual methods of writing and editing music.

  15. STS-103 crew take part in CEIT in PHSF

    NASA Technical Reports Server (NTRS)

    1999-01-01

    During a Crew Equipment Interface Test in the Payload Hazardous Servicing Facility, members of the STS-103 crew check out the Flight Support System (FSS)from above and below. The FSS is part of the primary payload on the mission to repair the Hubble Space Telescope. The seven-member crew comprises Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D), Claude Nicollier of Switzerland, and Jean-Frangois Clervoy of France. Nicollier and Clervoy are with the European Space Agency. Mission STS-103 is a 'call-up' due to the need to replace portions of the pointing system, the gyros, which have begun to fail on the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. The gyroscopes allow the telescope to point at stars, galaxies and planets. The STS-103 crew will not only replace gyroscopes, it will also replace a Fine Guidance Sensor and an older computer with a new enhanced model, an older data tape recorder with a solid-state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. The scheduled launch date in October is under review.

  16. STS-103 MS Clervoy and Commander Brown look over Discovery after landing

    NASA Technical Reports Server (NTRS)

    1999-01-01

    After landing at the Shuttle Landing Facility, STS-103 Mission Specialist Jean-Frangois Clervoy of France (left), with the European Space Agency (ESA), and Commander Curtis L. Brown Jr. (right) look over the orbiter Discovery. They and other crew members Pilot Scott J. Kelly and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.) and Claude Nicollier of Switzerland (also with ESA), completed a successful eight-day mission to service the Hubble Space Telescope, spending the Christmas holiday in space in order to accomplish their mission before the end of 1999. During the mission, Discovery's four space-walking astronauts, Smith, Foale, Grunsfeld and Nicollier, spent 24 hours and 33 minutes upgrading and refurbishing Hubble, making it more capable than ever to renew its observations of the universe. Mission objectives included replacing gyroscopes and an old computer, installing another solid state recorder, and replacing damaged insulation in the telescope. Hubble was released from the end of Discovery's robot arm on Christmas Day. Main gear touchdown was at 7:00:47 p.m. EST. Nose gear touchdown occurred at 7:00:58 EST and wheel stop at 7:01:34 EST. This was the 96th flight in the Space Shuttle program and the 27th for the orbiter Discovery. The landing was the 20th consecutive Shuttle landing in Florida and the 13th night landing in Shuttle program history.

  17. STS-103 Commander Brown DEPARTs PAFB for Houston

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Amidst a flurry of activity, STS-103 Commander Curtis L. Brown Jr. disembarks from the bus which brought him to the runway at Patrick Air Force Base in Cocoa Beach, Fla. The STS-103 crew and their families are preparing to board an airplane that will return them to their home base at the Johnson Space Center in Houston following the successful completion of their mission. Discovery landed in darkness the previous evening, Dec. 27, on runway 33 at KSC's Shuttle Landing Facility at 7:00:47 p.m. EST. This was the first time that a Shuttle crew spent the Christmas holiday in space. The other STS-103 crew members are Pilot Scott J. Kelly and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland and Jean-Frangois Clervoy of France. The STS-103 mission accomplished outfitting the Hubble Space Telescope with six new gyroscopes, six new voltage/temperature improvement kits, a new onboard computer, a new solid state recorder and new data transmitter, a new fine guidance sensor along with new insulation on parts of the orbiting telescope. This was the 96th flight in the Space Shuttle program and the 27th for the orbiter Discovery.

  18. STS-103 Commander Brown introduces crew during interview at Pad 39B

    NASA Technical Reports Server (NTRS)

    1999-01-01

    At Launch Pad 39B, STS-103 Commander Curtis L. Brown Jr. introduces the rest of the crew: (left to right) Pilot Scott J. Kelly and Mission Specialists Steven L. Smith, Jean-Frangois Clervoy of France, who is with the European Space Agency (ESA), John M. Grunsfeld (Ph.D.), C. Michael Foale (Ph.D.), and Claude Nicollier of Switzerland, who is also with ESA. As a preparation for launch, they have been participating in Terminal Countdown Demonstration Test (TCDT) activities at KSC. The TCDT provides the crew with emergency egress training, opportunities to inspect their mission payloads in the orbiter's payload bay, and simulated countdown exercises. STS-103 is a 'call-up' mission due to the need to replace and repair portions of the Hubble Space Telescope, including the gyroscopes that allow the telescope to point at stars, galaxies and planets. The STS-103 crew will be replacing a Fine Guidance Sensor, an older computer with a new enhanced model, an older data tape recorder with a solid-state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The mission is targeted for launch Dec. 6 at 2:37 a.m. EST.

  19. STS-103 Commander Brown and his fiancee DEPART PAFB for Houston

    NASA Technical Reports Server (NTRS)

    1999-01-01

    STS-103 Commander Curtis L. Brown Jr. and his fiancee, Ann Brickert, smile for the camera on the runway at Patrick Air Force Base in Cocoa Beach, Fla. The STS-103 crew and their families are preparing to board an airplane that will return them to their home base at the Johnson Space Center in Houston following the successful completion of their mission. Discovery landed in darkness the previous evening, Dec. 27, on runway 33 at KSC's Shuttle Landing Facility at 7:00:47 p.m. EST. This was the first time that a Shuttle crew spent the Christmas holiday in space. The other STS-103 crew members are Pilot Scott J. Kelly and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland and Jean-Frangois Clervoy of France. The STS-103 mission accomplished outfitting the Hubble Space Telescope with six new gyroscopes, six new voltage/temperature improvement kits, a new onboard computer, a new solid state recorder and new data transmitter, a new fine guidance sensor along with new insulation on parts of the orbiting telescope. This was the 96th flight in the Space Shuttle program and the 27th for the orbiter Discovery.

  20. STS-103 M.S. Michael Foale during TCDT activities

    NASA Technical Reports Server (NTRS)

    1999-01-01

    STS-103 Mission Specialist C. Michael Foale (Ph.D.) is ready to take his turn at driving a small armored personnel carrier that is part of emergency egress training during Terminal Countdown Demonstration Test (TCDT) activities. The tracked vehicle could be used by the crew in the event of an emergency at the pad during which the crew must make a quick exit from the area. The TCDT also provides simulated countdown exercises and opportunities to inspect the mission payloads in the orbiter's payload bay. STS-103 is a 'call-up' mission due to the need to replace and repair portions of the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The other STS-103 crew members are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, and Mission Specialists Steven L. Smith , John M. Grunsfeld (Ph.D.), and Claude Nicollier of Switzerland and Jean-Frangois Clervoy of France, who are with the European Space Agency. The mission is targeted for launch Dec. 6 at 2:37 a.m. EST.

  1. STS-103 Pilot Kelly and Commander Brown look over Discovery after landing

    NASA Technical Reports Server (NTRS)

    1999-01-01

    After landing at the Shuttle Landing Facility, STS-103 Pilot Scott J. Kelly (left) and Commander Curtis L. Brown Jr. (right) look at the tiles on orbiter Discovery. They and other crew members Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Jean-Francois Clervoy of France and Claude Nicollier of Switzerland, completed a successful eight-day mission to service the Hubble Space Telescope, spending the Christmas holiday in space in order to accomplish their mission before the end of 1999. During the mission, Discovery's four space-walking astronauts, Smith, Foale, Grunsfeld and Nicollier, spent 24 hours and 33 minutes upgrading and refurbishing Hubble, making it more capable than ever to renew its observations of the universe. Mission objectives included replacing gyroscopes and an old computer, installing another solid state recorder, and replacing damaged insulation in the telescope. Hubble was released from the end of Discovery's robot arm on Christmas Day. Main gear touchdown was at 7:00:47 p.m. EST. Nose gear touchdown occurred at 7:00:58 EST and wheel stop at 7:01:34 EST. This was the 96th flight in the Space Shuttle program and the 27th for the orbiter Discovery. The landing was the 20th consecutive Shuttle landing in Florida and the 13th night landing in Shuttle program history.

  2. STS-103 Commander Brown answers question during interview at Pad 39B

    NASA Technical Reports Server (NTRS)

    1999-01-01

    STS-103 Commander Curtis L. Brown Jr. answers a question from the media about the mission. As a preparation for launch, the crew have been participating in Terminal Countdown Demonstration Test (TCDT) activities at KSC. The TCDT provides the crew with emergency egress training, opportunities to inspect their mission payloads in the orbiter's payload bay, and simulated countdown exercises. Other crew members are Pilot Scott J. Kelly, and Mission Specialists Steven L. Smith, Jean-Frangois Clervoy of France, who is with the European Space Agency (ESA), John M. Grunsfeld (Ph.D.), C. Michael Foale (Ph.D.), and Claude Nicollier of Switzerland, who is also with ESA. STS-103 is a 'call-up' mission due to the need to replace and repair portions of the Hubble Space Telescope, including the gyroscopes that allow the telescope to point at stars, galaxies and planets. The STS-103 crew will be replacing a Fine Guidance Sensor, an older computer with a new enhanced model, an older data tape recorder with a solid-state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The mission is targeted for launch Dec. 6 at 2:37 a.m. EST.

  3. STS-103 MS Clervoy and Nicollier and Commander Brown look over Discovery after landing

    NASA Technical Reports Server (NTRS)

    1999-01-01

    After landing at the Shuttle Landing Facility, STS-103 Mission Specialists Jean-Francois Clervoy of France and Claude Nicollier of Switzerland, who are with the European Space Agency, listen to a comment by Commander Curtis L. Brown Jr. while looking over the orbiter Discovery. Other members of the crew are Pilot Scott J. Kelly and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), and John M. Grunsfeld (Ph.D.). The crew of seven completed a successful eight-day mission to service the Hubble Space Telescope, spending the Christmas holiday in space in order to accomplish their mission before the end of 1999. During the mission, Discovery's four space-walking astronauts, Smith, Foale, Grunsfeld and Nicollier, spent 24 hours and 33 minutes upgrading and refurbishing Hubble, making it more capable than ever to renew its observations of the universe. Mission objectives included replacing gyroscopes and an old computer, installing another solid state recorder, and replacing damaged insulation in the telescope. Hubble was released from the end of Discovery's robot arm on Christmas Day. Main gear touchdown was at 7:00:47 p.m. EST. Nose gear touchdown occurred at 7:00:58 EST and wheel stop at 7:01:34 EST. This was the 96th flight in the Space Shuttle program and the 27th for the orbiter Discovery. The landing was the 20th consecutive Shuttle landing in Florida and the 13th night landing in Shuttle program history.

  4. STS-103 crew take part in CEIT

    NASA Technical Reports Server (NTRS)

    1999-01-01

    In the Payload Hazardous Servicing Facility, the STS-103 crew look over equipment to be used during their mission. The seven-member crew, taking part in a Crew Equipment Interface Test, are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland, and Jean-Frangois Clervoy of France. Nicollier and Clervoy are with the European Space Agency. Mission STS-103 is a 'call-up' due to the need to replace portions of the pointing system, the gyros, which have begun to fail on the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. The gyroscopes allow the telescope to point at stars, galaxies and planets. The STS-103 crew will not only replace gyroscopes, it will also replace a Fine Guidance Sensor and an older computer with a new enhanced model, an older data tape recorder with a solid state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. The scheduled launch date in October is under review.

  5. STS-103 crew take part in CEIT

    NASA Technical Reports Server (NTRS)

    1999-01-01

    During a Crew Equipment Interface Test, members of the STS-103 crew check out new Multi-Layer Insulation (MLI) for the Hubble Space Telescope. The payload hardware is in the Payload Hazardous Servicing Facility. From left are Mission Specialists Claude Nicollier of Switzerland, Steven L. Smith, C. Michael Foale (Ph.D.), and John M. Grunsfeld (Ph.D.). Other members of the crew are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, and Mission Specialist Jean-Frangois Clervoy of France. Nicollier and Clervoy are with the European Space Agency. Mission STS-103 is a 'call-up' due to the need to replace portions of the pointing system, the gyros, which have begun to fail on the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. The gyroscopes allow the telescope to point at stars, galaxies and planets. The STS-103 crew will not only replace gyroscopes, it will also replace a Fine Guidance Sensor and an older computer with a new enhanced model, an older data tape recorder with a solid state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with the MLI. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. The scheduled launch date in October is under review.

  6. Gay re-readings of the Harlem Renaissance poets.

    PubMed

    Woods, G

    1993-01-01

    In the light of the long-established fact of their homosexuality or bisexuality, it is high time for the cluster of "Negro Renaissance" poets, Countee Cullen, Langston Hughes, Claude McKay, and Richard Bruce Nugent, to be reappraised by and for gay readers. This paper seeks to develop gay reading strategies in relation to the poems of these writers, in order to reveal for contemporary readers likely subtexts which, at the time of their writing, were publicly read as bearing on race alone. It is often possible to read a particular poem as referring (in images such as that of the social outcast) to either racial or sexual oppression, interchangeably; and possibly, therefore, to both at once, by way of an implicit comparison. Likewise, poems on miscegenation can just as well be read, via the theme of forbidden love, as referring to homosexuality. The fact that most published critical readings deal only with the racial issue does not invalidate the likelihood that the poem can be, and indeed requires to be, read as referring, also, to sexuality. Gay readings emerge, then, not merely from these writers' representations of attractive men and boys, but also in the midst of their most famously anti-racist themes.

  7. STS-103 Discovery crawls to Launch Pad 39B

    NASA Technical Reports Server (NTRS)

    1999-01-01

    With the American flag flapping in the morning breeze, Space Shuttle Discovery across the turn basin makes its 4.2-mile (6.8 kilometer) crawl to Launch Pad 39B (background, left) atop the mobile launcher platform and crawler transporter. Once at the pad, the orbiter, external tank and solid rocket boosters will undergo final preparations for the STS-103 launch targeted for Dec. 6, 1999, at 2:37 a.m. EST. The mission is a 'call-up' due to the need to replace and repair portions of the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The STS-103 crew members are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), and Claude Nicollier of Switzerland and Jean-Frangois Clervoy of France, both with the European Space Agency.

  8. Does Stereotype Threat Affect Post-Course Scores on the Astronomy Diagnostic Test?

    NASA Astrophysics Data System (ADS)

    Deming, G. L.; Hufnagel, B.; Landato, J. M.; Hodari, A. K.

    2003-12-01

    During the 1990s, Claude Steele and others demonstrated that women mathematics students under-performed while men over-performed on selected GRE questions when told that the exam could differentiate by gender. Stereotype threat is triggered for these women when they fear someone else may negatively stereotype them, and therefore, their performance is affected. In a limited study involving 229 students, we investigated the effect of stereotype threat on performance on the Astronomy Diagnostic Test (ADT). The ADT was administered as a pre-test in four introductory astronomy classes intended for non-science majors. The same professors taught pairs of classes at the University of Maryland, a large research institution, and W. R. Harper College, a small liberal arts school. The classes were treated the same until the final day before the post-course ADT was given. One "threatened" class at each campus was told that gender mattered so they should be sure to include it on the ADT. The "control" classes were told that gender does not matter. The results show no stereotype threat effect on the women in these introductory classes. The university men did slightly over-perform at low statistical significance. As Steele suggested, students must identify with a subject in order to strongly invoke a stereotype threat. This research was supported in part by the National Science Foundation through grants REC-0089239 to GLD, DGE-97014489 to BH, and DGE-9714452 for AKH.

  9. STS-75 liftoff - clearing tower thru trees

    NASA Technical Reports Server (NTRS)

    1996-01-01

    The Space Shuttle Columbia hurtles skyward from Launch Pad 39B. Columbia lifted off right on time at 3:18:00 p.m. EST, Feb. 22, following a smooth countdown. NASA's second Shuttle mission of 1996 and the 75th overall in Shuttle program history will be highlighted by the re-flight of the Tethered Satellite System (TSS-1R) designed to investigate new sources of spacecraft power and ways to study Earth's atmosphere. Mission STS-75 also will see Columbia's seven-person crew work with the U.S. Microgravity Payload (USMP-3), which continues research efforts into development of new materials and processes that could lead to a new generation of computers, electronics and metals. The STS-75 crew includes: Mission Commander Andrew M. Allen; Pilot Scott J. 'Doc' Horowitz; Payload Commander Franklin R. Chang-Diaz; Mission Specialists Jeffrey A. Hoffman, Claude Nicollier and Maurizio Cheli; and Payload Specialist Umberto Guidoni. Nicollier and Cheli represent the European Space Agency (ESA) while Guidoni represents the Italian Space Agency (ASI).

  10. SNPnexus: a web database for functional annotation of newly discovered and public domain single nucleotide polymorphisms

    PubMed Central

    Chelala, Claude; Khan, Arshad; Lemoine, Nicholas R

    2009-01-01

    Motivation: Design a new computational tool allowing scientists to functionally annotate newly discovered and public domain single nucleotide polymorphisms in order to help in prioritizing targets in further disease studies and large-scale genotyping projects. Summary: SNPnexus database provides functional annotation for both novel and public SNPs. Possible effects on the transcriptome and proteome levels are characterized and reported from five major annotation systems providing the most extensive information on alternative splicing. Additional information on HapMap genotype and allele frequency, overlaps with potential regulatory elements or structural variations as well as related genetic diseases can be also retrieved. The SNPnexus database has a user-friendly web interface, providing single or batch query options using SNP identifiers from dbSNP as well as genomic location on clones, contigs or chromosomes. Therefore, SNPnexus is the only database currently providing a complete set of functional annotations of SNPs in public databases and newly detected from sequencing projects. Hence, we describe SNPnexus, provide details of the query options, the annotation categories as well as biological examples of use. Availability: The SNPnexus database is freely available at http://www.snp-nexus.org. Contact: claude.chelala@cancer.org.uk PMID:19098027

  11. STS-103 crew take part in CEIT

    NASA Technical Reports Server (NTRS)

    1999-01-01

    In the Payload Hazardous Servicing Facility, a member of the STS-103 crew checks out rib clamp to be used on the Shield Shell Replacement Fabric (SSRF) task on repair of the Hubble Space Telescope. The seven-member crew, taking part in a Crew Equipment Interface Test, are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland, and Jean-Frangois Clervoy of France. Nicollier and Clervoy are with the European Space Agency. Mission STS-103 is a 'call-up' due to the need to replace portions of the pointing system, the gyros, which have begun to fail on the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. The gyroscopes allow the telescope to point at stars, galaxies and planets. The STS-103 crew will not only replace gyroscopes, it will also replace a Fine Guidance Sensor and an older computer with a new enhanced model, an older data tape recorder with a solid state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. The scheduled launch date in October is under review.

  12. STS-103 M.S. Steven Smith during TCDT activities

    NASA Technical Reports Server (NTRS)

    1999-01-01

    STS-103 Mission Specialist Steven L. Smith gets ready to practice driving a small armored personnel carrier that is part of emergency egress training during Terminal Countdown Demonstration Test (TCDT) activities. The tracked vehicle could be used by the crew in the event of an emergency at the pad during which the crew must make a quick exit from the area. The TCDT also provides simulated countdown exercises and opportunities to inspect the mission payloads in the orbiter's payload bay. STS-103 is a 'call-up' mission due to the need to replace and repair portions of the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The other STS-103 crew members are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, and Mission Specialists John M. Grunsfeld (Ph.D.), C. Michael Foale (Ph.D.), (Ph.D.), and Claude Nicollier of Switzerland and Jean-Frangois Clervoy of France, who are with the European Space Agency. The mission is targeted for launch Dec. 6 at 2:37 a.m. EST.

  13. The latest developments and outlook for hydrogen liquefaction technology

    SciTech Connect

    Ohlig, K.; Decker, L.

    2014-01-29

    Liquefied hydrogen is presently mainly used for space applications and the semiconductor industry. While clean energy applications, for e.g. the automotive sector, currently contribute to this demand with a small share only, their demand may see a significant boost in the next years with the need for large scale liquefaction plants exceeding the current plant sizes by far. Hydrogen liquefaction for small scale plants with a maximum capacity of 3 tons per day (tpd) is accomplished with a Brayton refrigeration cycle using helium as refrigerant. This technology is characterized by low investment costs but lower process efficiency and hence higher operating costs. For larger plants, a hydrogen Claude cycle is used, characterized by higher investment but lower operating costs. However, liquefaction plants meeting the potentially high demand in the clean energy sector will need further optimization with regard to energy efficiency and hence operating costs. The present paper gives an overview of the currently applied technologies, including their thermodynamic and technical background. Areas of improvement are identified to derive process concepts for future large scale hydrogen liquefaction plants meeting the needs of clean energy applications with optimized energy efficiency and hence minimized operating costs. Compared to studies in this field, this paper focuses on application of new technology and innovative concepts which are either readily available or will require short qualification procedures. They will hence allow implementation in plants in the close future.

  14. Web-based Teaching Radio Interferometer for Africa

    NASA Astrophysics Data System (ADS)

    Carignan, Claude

    2015-08-01

    Practical training for the future use of the African VLBI Network (AVN) or any VLBI experiment starts by understanding the basic principles of radio observations and radio interferometry. The aim of this project is to build a basic interferometer that could be used remotely via a web interface from any country on the African continent. This should turn out as a much less expensive and much more efficient way to train AVN researchers from SKA partner countries to the principles of radio astronomy and to interferometric data analysis. The idea is based on the very successful EUHOU (European Hands-On Universe) already very successful in Europe. The former EUHOU manager, Dr Yannick Liebert, arrived for a 3 years postdoc with Prof Claude Carignan at the University of Cape Town to implement the same project on the African continent (AHI: African Hands-on Interferometry). Besides the use of AHI for the AVN researchers, this web-based system could be used be any undergraduate program on radio astronomical techniques across the African continent as the EUHOU is used all across Europe.

  15. Laser Cooling and Trapping of Neutral Atoms

    NASA Astrophysics Data System (ADS)

    Phillips, William D.

    1998-05-01

    Laser cooling was proposed in 1975 and first demonstrated for trapped ions in 1978, but the effective laser cooling of neutral atoms took longer, in part because neutrals are so hard to trap. Laser deceleration and cooling of an atomic beam came in the early 1980s, followed by magnetic trapping of atoms in 1985. In 1988 we discovered that laser cooling results in temperatures far lower than expected from the then-accepted theory. The new understanding, developed in the groups of Claude Cohen-Tannoudji and Steve Chu, of the physical process of laser cooling has allowed us to achieve temperatures below a microkelvin. Today, laser cooling and trapping is being used for applications ranging from atomic clocks to Bose-Einstein condensation. This talk is an adaptation of the Nobel Lecture given in Stockholm, December 1997. Special thanks go to my colleagues at NIST and to the entire laser cooling community. This work was supported by NIST and by the ONR.

  16. Quantum Mechanics, Volume 1

    NASA Astrophysics Data System (ADS)

    Cohen-Tannoudji, Claude; Diu, Bernard; Laloe, Frank

    1986-06-01

    Beginning students of quantum mechanics frequently experience difficulties separating essential underlying principles from the specific examples to which these principles have been historically applied. Nobel-Prize-winner Claude Cohen-Tannoudji and his colleagues have written this book to eliminate precisely these difficulties. Fourteen chapters provide a clarity of organization, careful attention to pedagogical details, and a wealth of topics and examples which make this work a textbook as well as a timeless reference, allowing to tailor courses to meet students' specific needs. Each chapter starts with a clear exposition of the problem which is then treated, and logically develops the physical and mathematical concept. These chapters emphasize the underlying principles of the material, undiluted by extensive references to applications and practical examples which are put into complementary sections. The book begins with a qualitative introduction to quantum mechanical ideas using simple optical analogies and continues with a systematic and thorough presentation of the mathematical tools and postulates of quantum mechanics as well as a discussion of their physical content. Applications follow, starting with the simplest ones like e.g. the harmonic oscillator, and becoming gradually more complicated (the hydrogen atom, approximation methods, etc.). The complementary sections each expand this basic knowledge, supplying a wide range of applications and related topics as well as detailed expositions of a large number of special problems and more advanced topics, integrated as an essential portion of the text.

  17. "The Civil Rights Movement of the 1990s?": The anti-abortion movement and the struggle for racial justice.

    PubMed

    Hughes, Richard L

    2006-01-01

    In 1964, Claude and Jeanne Nolen, who were white, joined an interracial NAACP team intent on desegregating local restaurants in Austin, Texas as a test of the recently passed Civil Rights ACt. Twenty-five years later, the Nolens pleaded "no contest" in a courtroom for their continued social activism. This time the issue was not racial segregation, but rather criminal trespassing for blockading abortion clinics with Operation Rescue. The Nolens served prison sentences for direct action protests that they believe stemmed from the same commitment to Christianity and social justice as the civil rights movements. Despite its relationship to political and cultural conservatism, the anti-abortion movement since Roe v. Wade (1973) was also a product of the progressive social movements of the turbulent sixties. Utilizing oral history interviews and organizational literature, the article explores the historical context of the anti-abortion movement, specifically how the lengthy struggle for racial justice shaped the rhetoric, tactics, and ideology of the anti-abortion activists. Even after political conservatives dominated the movement in the 1980s, the successes and failures of the sixties provided a cultural lens through which grassroots anti-abortion activists forged what was arguably the largest movement of civil disobedience in American history.

  18. Operational experience of the OC-OTEC experiments at NELH

    NASA Astrophysics Data System (ADS)

    Link, Hal

    1989-02-01

    The Solar Energy Research Institute, under funding and program direction from the U.S. Department of Energy, has been operating a small-scale test apparatus to investigate key components of open-cycle ocean thermal energy conversion (OC-OTEC). The apparatus started operations in October 1987 and continues to provide valuable information on heat- and mass-transfer processes in evaporators and condensers, gas sorption processes as seawater is depressurized and repressurized, and control and instrumentation characteristics of open-cycle systems. Although other test facilities have been used to study some of these interactions, this is the largest apparatus of its kind to use seawater since Georges Claude's efforts in 1926. The information obtained from experiments conducted in this apparatus is being used to design a larger scale experiment in which a positive net power production is expected to be demonstrated for the first time with OC-OTEC. This paper describes the apparatus, the major tests conducted during its first 18 months of operation, and the experience gained in OC-OTEC system operation.

  19. Ocean thermal energy conversion: Historical highlights, status, and forecast

    SciTech Connect

    Dugger, G.L.; Avery, W.H.; Francis, E.J.; Richards, D.

    1983-07-01

    In 1881, d'Arsonval conceived the closed-Rankine-cycle ocean thermal energy conversion (OTEC) system in which a working fluid is vaporized by heat exchange with cold water drawn from a 700-1200 m depth. In 1930, Claude demonstrated an open-cycle process in Cuba. Surface water was flash-vaporized at 3 kPa to drive a turbine directly (no secondary working fluid) and then was condensed by direct contact with water drawn from a 700-m depth through a 1.6m-diam, 1.75-km-long cold-water pipe (CWP). From a delta T of 14/sup 0/C his undersized turbine generated 22 kW. In 1956 a French team designed a 3.5-MW (net) open-cycle plant for installation off Abidjan on the Ivory Coast of Africa and demonstrated the necessary CWP deployment. The at-sea demonstrations by Mini-OTEC and OTEC-1 and other recent advances in OTEC technology summarized herein represent great progress. All of the types of plants proposed for the DOE's PON program may be worthy of development; certainly work on a grazing plant is needed. Our estimates indicate that the U.S. goals established by Public Law 96-310 leading to 10 GW of OTEC power and energy product equivalents by 1999 are achievable, provided that adequate federal financial incentives are retained to assure the building of the first few plants.

  20. Operational experience of the OC-OTEC experiments at NELH

    SciTech Connect

    Link, H.

    1989-02-01

    The Solar Energy Research Institute, under funding and program direction from the US Department of Energy, has been operating a small-scale test apparatus to investigate key components of open- cycle ocean thermal energy conversion (OC-OTEC). The apparatus started operations in October 1987 and continues to provide valuable information on heat-and mass-transfer processes in evaporators and condensers, gas sorption processes as seawater is depressurized and repressurized, and control and instrumentation characteristics of open-cycle systems. Although other test facilities have been used to study some of these interactions, this is the largest apparatus of its kind to use seawater since Georges Claude's efforts in 1926. The information obtained from experiments conducted in this apparatus is being used to design a larger scale experiment in which a positive net power production is expected to be demonstrated for the first time with OC-OTEC. This paper describes the apparatus, the major tests conducted during its first 18 months of operation, and the experience gained in OC-OTEC system operation. 13 refs., 8 figs.

  1. Integrated design of cryogenic refrigerator and liquid-nitrogen circulation loop for HTS cable

    NASA Astrophysics Data System (ADS)

    Chang, Ho-Myung; Ryu, Ki Nam; Yang, Hyung Suk

    2016-12-01

    A new concept of cryogenic cooling system is proposed and investigated for application to long-length HTS cables. One of major obstacles to the cable length of 1 km or longer is the difficulty in circulating liquid nitrogen (LN) along the cables, since the temperature rise and pressure drop of LN flow could be excessively large. This study attempts a breakthrough by integrating the refrigerator with the LN circulation loop in order to eliminate the cryogenic LN pumps, and generate a large LN flow with the power of compressors at ambient temperature. A variety of thermodynamic structures are investigated on standard and modified Claude cycles, where nitrogen is used as refrigerant and the LN circulation loop is included as part of the closed cycle. Four proposed cycles are fully analyzed and optimized with a process simulator (Aspen HYSYS) to evaluate the FOM (figure of merit) and examine the feasibility. The modified dual-pressure cycle cooled with expander stream is recommended for long HTS cables.

  2. STS-103 Pilot Kelly and MS Clervoy and Smith DEPART PAFB for Houston

    NASA Technical Reports Server (NTRS)

    1999-01-01

    STS-103 Pilot Scott J. Kelly holds his daughter as he talks to Mission Specialists and fellow crew members Jean-Frangois Clervoy of France and Steven L. Smith on the runway at Patrick Air Force Base in Cocoa Beach, Fla. The STS-103 crew and their families are preparing to board an airplane that will return them to their home base at the Johnson Space Center in Houston following the successful completion of their mission. Discovery landed in darkness the previous evening, Dec. 27, on runway 33 at KSC's Shuttle Landing Facility at 7:00:47 p.m. EST. This was the first time that a Shuttle crew spent the Christmas holiday in space. The other STS-103 crew members are Commander Curtis L. Brown Jr. and Mission Specialists C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), and Claude Nicollier of Switzerland. The STS-103 mission accomplished outfitting the Hubble Space Telescope with six new gyroscopes, six new voltage/temperature improvement kits, a new onboard computer, a new solid state recorder and new data transmitter, a new fine guidance sensor along with new insulation on parts of the orbiting telescope. This was the 96th flight in the Space Shuttle program and the 27th for the orbiter Discovery.

  3. STS-103 Payload Commander Smith and his wife DEPART PAFB for Houston

    NASA Technical Reports Server (NTRS)

    1999-01-01

    STS-103 Payload Commander Steven L. Smith and his wife, Peggy, smile for the camera on the runway at Patrick Air Force Base in Cocoa Beach, Fla. The STS-103 crew and their families are preparing to board an airplane that will return them to their home base at the Johnson Space Center in Houston following the successful completion of their mission. Discovery landed in darkness the previous evening, Dec. 27, on runway 33 at KSC's Shuttle Landing Facility at 7:00:47 p.m. EST. This was the first time that a Shuttle crew spent the Christmas holiday in space. The other STS-103 crew members are Commander Curtis L. Brown Jr.; Pilot Scott J. Kelly; and Mission Specialists C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland and Jean-Frangois Clervoy of France. The STS-103 mission accomplished outfitting the Hubble Space Telescope with six new gyroscopes, six new voltage/temperature improvement kits, a new onboard computer, a new solid state recorder and new data transmitter, a new fine guidance sensor along with new insulation on parts of the orbiting telescope. This was the 96th flight in the Space Shuttle program and the 27th for the orbiter Discovery.

  4. [The formative role of the laboratory in teaching the science of physiology].

    PubMed

    Guevara-Guzmán, Rosalinda; Urrutia Aguilar, María Esther

    2014-12-01

    Physiology teaching began with Claudius Galenus (c. 126-199 AD), known as Galen, who is considered the initiator of experimental physiology. This discipline was consolidated in the XIX century with the discoveries of Claude Bernard, which influenced the way of teaching this discipline in universities, independently from Anatomy. In Mexico, physiology teaching started in 1580. It was at the beginning of the XIX century when Valentín Gómez Farías created the professorship in Medical Sciences and Daniel Vergara Lope carried out its consolidation when he implemented a lab course. Doctor José Joaquín Izquierdo established that this subject ought to be taught by teachers with experience in research. Undoubtedly, formative physiology teaching carried out in labs must strengthen the application of method and scientific methodology in students. In this symposium, we put forward that the change in physiology teaching must promote multidisciplinary research in students, who will formulate a research question and develop an experimental model that will let them integrate their basic knowledge of physiology, pharmacology, biochemistry, and functional anatomy under the supervision of a research teacher.

  5. Heat transfer and flow friction correlations for perforated plate matrix heat exchangers

    NASA Astrophysics Data System (ADS)

    Ratna Raju, L.; Kumar, S. Sunil; Chowdhury, K.; Nandi, T. K.

    2017-02-01

    Perforated plate matrix heat exchangers (MHE) are constructed of high conductivity perforated plates stacked alternately with low conductivity spacers. They are being increasingly used in many cryogenic applications including Claude cycle or Reversed Brayton cycle cryo-refrigerators and liquefiers. Design of high NTU (number of (heat) transfer unit) cryogenic MHEs requires accurate heat transfer coefficient and flow friction factor. Thermo-hydraulic behaviour of perforated plates strongly depends on the geometrical parameters. Existing correlations, however, are mostly expressed as functions of Reynolds number only. This causes, for a given configuration, significant variations in coefficients from one correlation to the other. In this paper we present heat transfer and flow friction correlations as functions of all geometrical and other controlling variables. A FluentTM based numerical model has been developed for heat transfer and pressure drop studies over a stack of alternately arranged perforated plates and spacers. The model is validated with the data from literature. Generalized correlations are obtained through regression analysis over a large number of computed data.

  6. Looking at science on board Eureca

    NASA Astrophysics Data System (ADS)

    Minster, Olivier; Innocenti, Louisa; Mesland, Dick; Heerd, Stefan

    1993-05-01

    The European Retrievable Carrier (Eureca) is the first platform designed to be retrieved from orbit and possibly to be relaunched with a different payload. For its first mission in July 1992, Eureca was deployed from the Space Shuttle Atlantis (flight STS 46) by ESA astronaut and mission specialist, Claude Nicollier. It then used its own propulsion system to transfer to its operational orbit at 508 km where, after commissioning, payload operation started. Since Eureca has been specially designed for investigations in the microgravity environment, this publication concentrates mainly on this aspect of the mission. Microgravity research is a newcomer to the scientific disciplines and is perhaps not very well known to, or understood by, those not directly involved. An explanation of the microgravity environment is presented. This is followed by an explanation of the interest microgravity holds for researchers, and a review of the different scientific fields, Material Sciences, Fluid Physics, Life Sciences, for which investigations have been carried out during the Eureca mission, together with a brief description of the on-board facilities and their flight performances. The last two chapters describe the Space Science and technology experiments carried out during the mission.

  7. Color consilience: color through the lens of art practice, history, philosophy, and neuroscience.

    PubMed

    Conway, Bevil R

    2012-03-01

    Paintings can be interpreted as the product of the complex neural machinery that translates physical light signals into behavior, experience, and emotion. The brain mechanisms responsible for vision and perception have been sculpted during evolution and further modified by cultural exposure and development. By closely examining artists' paintings and practices, we can discover hints to how the brain works, and achieve insight into the discoveries and inventions of artists and their impact on culture. Here, I focus on an integral aspect of color, color contrast, which poses a challenge for artists: a mark situated on an otherwise blank canvas will appear a different color in the context of the finished painting. How do artists account for this change in color during the production of a painting? In the broader context of neural and philosophical considerations of color, I discuss the practices of three modern masters, Henri Matisse, Paul Cézanne, and Claude Monet, and suggest that the strategies they developed not only capitalized on the neural mechanisms of color, but also influenced the trajectory of western art history.

  8. Space polypropulsion

    NASA Astrophysics Data System (ADS)

    Kellett, B. J.; Griffin, D. K.; Bingham, R.; Campbell, R. N.; Forbes, A.; Michaelis, M. M.

    2008-05-01

    Hybrid space propulsion has been a feature of most space missions. Only the very early rocket propulsion experiments like the V2, employed a single form of propulsion. By the late fifties multi-staging was routine and the Space Shuttle employs three different kinds of fuel and rocket engines. During the development of chemical rockets, other forms of propulsion were being slowly tested, both theoretically and, relatively slowly, in practice. Rail and gas guns, ion engines, "slingshot" gravity assist, nuclear and solar power, tethers, solar sails have all seen some real applications. Yet the earliest type of non-chemical space propulsion to be thought of has never been attempted in space: laser and photon propulsion. The ideas of Eugen Saenger, Georgii Marx, Arthur Kantrowitz, Leik Myrabo, Claude Phipps and Robert Forward remain Earth-bound. In this paper we summarize the various forms of nonchemical propulsion and their results. We point out that missions beyond Saturn would benefit from a change of attitude to laser-propulsion as well as consideration of hybrid "polypropulsion" - which is to say using all the rocket "tools" available rather than possibly not the most appropriate. We conclude with three practical examples, two for the next decades and one for the next century; disposal of nuclear waste in space; a grand tour of the Jovian and Saturnian moons - with Huygens or Lunoxod type, landers; and eventually mankind's greatest space dream: robotic exploration of neighbouring planetary systems.

  9. STS-103 crew pose at 195-foot level of Fixed Service Structure

    NASA Technical Reports Server (NTRS)

    1999-01-01

    At the 195-foot level of the Fixed Service Structure on Launch Pad 39B, the STS-103 crew take a break from Terminal Countdown Demonstration Test (TCDT) activities. Standing from left to right are Mission Specialists Jean-Frangois Clervoy of France and Claude Nicollier of Switzerland, who are with the European Space Agency; Commander Curtis L. Brown Jr.; Pilot Scott J. Kelly; and Mission Specialists John M. Grunsfeld (Ph.D.), C. Michael Foale (Ph.D.) and Steven L. Smith. The TCDT provides the crew with the emergency egress training, opportunities to inspect their mission payloads in the orbiter's payload bay, and simulated countdown exercises. STS-103 is a 'call-up' mission due to the need to replace and repair portions of the Hubble Space Telescope, including the gyroscopes that allow the telescope to point at stars, galaxies and planets. The STS-103 crew will be replacing a Fine Guidance Sensor, an older computer with a new enhanced model, an older data tape recorder with a solid-state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The mission is targeted for launch Dec. 6 at 2:37 a.m. EST.

  10. Status of the "ETOILE" project for a French hadrontherapy centre.

    PubMed

    Bajard, Marcel; De Conto, Jean-Marie; Remillieux, Joseph

    2004-12-01

    It is proposed to build a national centre for light-ion hadrontherapy in France, located in Lyon in the Rhône-Alpes region. Under the auspices of University Claude Bemard Lyon-I and with the support of a research contract between Rhône-Alpes region and the Minister of Research, a design has been elaborated. This paper reviews the medical and technical characteristics of the project, called ETOILE (Espace de Traitement Oncologique par Ions Légers dans le cadre Européen). The research programs associated with ETOILE concern mainly the tracking of moving organs, the design of an in-beam PET detector, the simulation of the interaction of carbon ions with tissues and radiobiological studies on the radiosensitivity and tolerance of normal tissues and on the radioresistance of tumours. The capital cost needed to realize ETOILE is about 90 M Euro. We expect a definitive decision to build ETOILE at the end of 2004. In that case the centre will treat its first patients in 2009. A routine flux of 1000 patients per year will be reached after 3 years with an operation cost of 15 M Euro.

  11. A physiologist's view of homeostasis

    PubMed Central

    Cliff, William; Michael, Joel; McFarland, Jenny; Wenderoth, Mary Pat; Wright, Ann

    2015-01-01

    Homeostasis is a core concept necessary for understanding the many regulatory mechanisms in physiology. Claude Bernard originally proposed the concept of the constancy of the “milieu interieur,” but his discussion was rather abstract. Walter Cannon introduced the term “homeostasis” and expanded Bernard's notion of “constancy” of the internal environment in an explicit and concrete way. In the 1960s, homeostatic regulatory mechanisms in physiology began to be described as discrete processes following the application of engineering control system analysis to physiological systems. Unfortunately, many undergraduate texts continue to highlight abstract aspects of the concept rather than emphasizing a general model that can be specifically and comprehensively applied to all homeostatic mechanisms. As a result, students and instructors alike often fail to develop a clear, concise model with which to think about such systems. In this article, we present a standard model for homeostatic mechanisms to be used at the undergraduate level. We discuss common sources of confusion (“sticky points”) that arise from inconsistencies in vocabulary and illustrations found in popular undergraduate texts. Finally, we propose a simplified model and vocabulary set for helping undergraduate students build effective mental models of homeostatic regulation in physiological systems. PMID:26628646

  12. STS-103 Commander Curtis Brown during TCDT activities

    NASA Technical Reports Server (NTRS)

    1999-01-01

    STS-103 Commander Curtis L. Brown Jr. gets ready to take the helm of a small armored personnel carrier that is part of emergency egress training during Terminal Countdown Demonstration Test (TCDT) activities. The tracked vehicle could be used by the crew in the event of an emergency at the pad during which the crew must make a quick exit from the area. The TCDT also provides simulated countdown exercises and opportunities to inspect the mission payloads in the orbiter's payload bay. STS-103 is a 'call-up' mission due to the need to replace and repair portions of the Hubble Space Telescope. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The other STS-103 crew members are Pilot Scott J. Kelly, and Mission Specialists Steven L. Smith , C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), plus Claude Nicollier of Switzerland and Jean-Frangois Clervoy of France, who are with the European Space Agency. The mission is targeted for launch Dec. 6 at 2:37 a.m. EST.

  13. STS-103 crew take part in CEIT

    NASA Technical Reports Server (NTRS)

    1999-01-01

    In the Payload Hazardous Servicing Facility, STS-103 Mission Specialist Steven L. Smith (right) and other members of the crew look over new Multi-Layer Insulation (MLI) intended for the Hubble Space Telescope. The seven-member crew, taking part in a Crew Equipment Interface Test, are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, and Mission Specialists Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland, and Jean-Frangois Clervoy of France. Nicollier and Clervoy are with the European Space Agency. Mission STS-103 is a 'call-up' due to the need to replace portions of the pointing system, the gyros, which have begun to fail on the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. The gyroscopes allow the telescope to point at stars, galaxies and planets. The STS-103 crew will not only replace gyroscopes, it will also replace a Fine Guidance Sensor and an older computer with a new enhanced model, an older data tape recorder with a solid state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with the MLI. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. The scheduled launch date in October is under review.

  14. Theoretical study on the efficacy of the cold compressor based cryogenic cycles

    NASA Astrophysics Data System (ADS)

    Jadhav, Mohananand; Chakravarty, A.; Atrey, M. D.

    2017-02-01

    Cold compressor based cycles have emerged as practical necessity for sub 4.5K (sub atmospheric) large scale cryogenic systems as used in most modern high energy accelerators and tokamaks. The concept of cold compressor can be applied in a generalized way for even atmospheric (high pressure) cycles, if justified. A rise in temperature is exhibited at the exit of the cold compressor due to pressurization and the inefficiency involved in the process. This rise in temperature results in gain of sensible heat, and acts like a refrigeration load at that temperature. This loss can only be acceptable if other advantages of cold compressors are substantial. In the present work, it is tried to explore the possibility of using the emerged cold compressor technology for medium scale cryogenics. One of the objectives of the study is to develop a cold compressor based refrigeration cycle which can be implemented using the present infrastructure at Cryo-Technology Division, Bhabha Atomic Research Centre (BARC). In this endeavour, a cryogenic cycle analysis tool is developed and is validated against the process data available for 2K cryogenic plant at LHC. Three cold compressor based modifications are proposed to the presently installed modified Claude cycle based helium liquefier. These three cases are analysed and compared.

  15. A History of Chemistry (by Bernadette Bensaude-Vincent and Isabelle Stengers)

    NASA Astrophysics Data System (ADS)

    Kauffman, George B.

    1998-06-01

    translated by Deborah van Dam. Harvard University Press: Cambridge, MA and London, 1997. 305 pp. Illustrations. 16.3 x 24.0 cm. ISBN 0-674-39659-6. $35.00, £23.50. Another history of chemistry? When I studied the subject in 1950 in the late Claude K. Deischer's class at the University of Pennsylvania, our text was Frank J. Moore's A History of Chemistry (1918; 3rd ed., 1939), one of the few books, all written by practicing chemists, then available in English. Now, paradoxically, at a time when such classes are no longer a standard part of the usual undergraduate curriculum, we are treated to a plethora of histories, most written by professional historians of science. In two recent years alone four histories have appeared: David M. Knight's Ideas in Chemistry: A History of the Science (Rutgers University Press, 1992), William H. Brock's The History of Chemistry (Chapman & Hall, 1992), William H. Brock's The Norton History of Chemistry (Norton, 1993), and Bernadette Bensaude-Vincent and Isabelle Stengers's Histoire de la Chimie (Editions de la Decuoverte, 1993). The book under review here is a felicitous English translation of the last-named volume.

  16. Astronomical Dating of Monet's Paintings on the Normandy Coast

    NASA Astrophysics Data System (ADS)

    Olson, D. W.

    2016-01-01

    Claude Monet (1840-1926) is famous for landscapes accurately capturing the changing nature of seas and skies. Monet created almost two thousand paintings during his long career, and several hundred of these works depict the skies above the spectacular cliffs, arches, rocks, harbors, and beaches on the Normandy coast. Our Texas State University group made a research trip to Normandy in the summer of 2012 and found dozens of the locations where Monet set up his easel. Astronomical considerations of daylight, twilight, night skies, and tides can be used to enhance our understanding of the artist's creative process. Monet himself said, “I need the Sun or the cloudy weather to coincide again with the tide, which must be low or high in accordance with my motifs.” Astronomical methods can be used to help in dating these works, many of which have uncertain dates in the existing catalogues and literature about Monet in Normandy. Analysis using the direction of sunlight and the direction of shadows, combined with calculations of lunar phases and tide levels, meteorological records, and the artist's letters, enables us to determine the exact date and the precise time, accurate to the minute, when Monet observed the sky that inspired a painting.

  17. [The production of optical glass in France and the experiences of Ruggiero Boscovich for the production of lead glass (Part One)].

    PubMed

    Proverbio, Edoardo

    The experiences that in 1758 led John Dollond to create the first achromatic telescope highlighted the serious difficulties related to the production of lenses with a correction for chromatic aberration. These difficulties were due to the lack of suitable tools for measuring the refraction index and for verifying the curvatures of the lenses of such optical instruments. To this was added what was perhaps the greatest difficulty: i.e., that of acquiring the kinds of glass, the so-called "common" (crown) glass and "lead" (flint) glass, of which the lenses had to be made. If the theoretical works of Alexis Clairaut, of Samuel Klingenstierna, and of Ruggiero Boscovich furnished the theoretical basis for producing such lenses, and subsequently--after Boscovich's discovery of the role of the eyepieces--for creating also achromatic eyepieces, the greatest challenge from the practical point of view was that of the availability of the flint glass. In this first part of the article there is then a study of the numerous attempts and directions pursued by Clairaut and his valid collaborators--Anthéaulme, George father and son, Charles François de l'Etang, and Claude Siméon Passemant--in order to find common glass and lead glass, and to produce the first achromatic lenses and binoculars in France. An analysis follows of the experiences conducted by Boscovich, first in Vienna, and then in Milan and Venice-Murano, addressed to the production of flint glass.

  18. Epidemiology: second-rate science?

    PubMed

    Parascandola, M

    1998-01-01

    In recent years epidemiology has come under increasing criticism in regulatory and public arenas for being "unscientific." The tobacco industry has taken advantage of this, insisting for decades that evidence linking cigarettes and lung cancer falls short of proof. Moreover, many epidemiologists remain unduly skeptical and self-conscious about the status of their own causal claims. This situation persists in part because of a widespread belief that only the laboratory can provide evidence sufficient for scientific proof. Adherents of this view erroneously believe that there is no element of uncertainty or inductive inference in the "direct observation" of the laboratory researcher and that epidemiology provides mere "circumstantial" evidence. The historical roots of this attitude can be traced to philosopher John Stuart Mill and physiologist Claude Bernard and their influence on modern experimental thinking. The author uses the debate over cigarettes and lung cancer to examine ideas of proof in medical science and public health, concluding that inductive inference from a limited sample to a larger population is an element in all empirical science.

  19. Transcriptional and post-translational regulation of pannexins.

    PubMed

    Boyce, Andrew K J; Epp, Anna L; Nagarajan, Archana; Swayne, Leigh Anne

    2017-03-07

    Pannexins are a 3-membered family of proteins that form large pore ion and metabolite channels in vertebrates. The impact of pannexins on vertebrate biology is intricately tied to where and when they are expressed, and how they are modified, once produced. The purpose of this review is therefore to outline our current understanding of transcriptional and post-translational regulation of pannexins. First, we briefly summarize their discovery and characteristics. Next, we describe several aspects of transcriptional regulation, including cell and tissue-specific expression, dynamic expression over development and disease, as well as new insights into the underlying molecular machinery involved. Following this, we delve into the role of post-translational modifications in the regulation of trafficking and channel properties, highlighting important work on glycosylation, phosphorylation, S-nitrosylation and proteolytic cleavage. Embedded throughout, we also highlight important knowledge gaps and avenues of future research. This article is part of a Special Issue entitled: Gap Junction Proteins edited by Jean Claude Herve.

  20. Johann Friedrich Horner and the Repeated Discovery of Oculosympathoparesis: Whose Syndrome Is It?

    PubMed

    Abbas, Ahmed; Manjila, Sunil; Singh, Mantinderpreet; Belle, Vaijayantee; Chandar, Krishan; Miller, Jonathan P

    2015-09-01

    Disruption of cranial sympathetic tone leads to the symptom complex of miosis, ptosis, and hemifacial anhidrosis. It is widely believed that this phenomenon was discovered in 1869 by the Swiss ophthalmologist Johann Friedrich Horner, and as a result, the term Horner syndrome has become synonymous with the clinical presentation. However, the syndrome that would become Horner syndrome had actually been described several times before his report. François Pourfour du Petit documented the ocular effects of sympathetic trunk lesions in animal studies in 1727. Claude Bernard identified the full clinical triad in animal studies in 1852, and as a result, the condition is sometimes called Bernard syndrome. There were also 2 previous reports of ptosis and miosis resulting from sympathetic nerve damage in humans: 1 by Edward Selleck Hare in 1838 associated with brachial plexus tumor, and the other by Silas Weir Mitchell in 1864 associated with a gunshot wound to the neck. Although Horner was the first to objectively characterize the co-occurrence of vasomotor and ocular changes in a human patient, he did not identify the etiology of the condition, discuss its relationship to the sympathetic nervous system, or reference any of the previous studies in animals or humans. It is possible that a lack of familiarity with previous investigations delayed the full appreciation of the mechanism underlying this disorder.

  1. STS-103 crew take part in CEIT

    NASA Technical Reports Server (NTRS)

    1999-01-01

    In the Payload Hazardous Servicing Facility, some of the STS-103 crew look over lubrication devices to be used during their mission. The seven-member crew are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland, and Jean-Frangois Clervoy of France. Nicollier and Clervoy are with the European Space Agency. Mission STS-103 is a 'call-up' due to the need to replace portions of the pointing system, the gyros, which have begun to fail on the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. The gyroscopes allow the telescope to point at stars, galaxies and planets. The STS-103 crew will not only replace gyroscopes, it will also replace a Fine Guidance Sensor and an older computer with a new enhanced model, an older data tape recorder with a solid state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. The scheduled launch date in October is under review.

  2. Chess as a Behavioral Model for Cognitive Skill Research: Review of Blindfold Chess by Eliot Hearst and John Knott

    PubMed Central

    Mechner, Francis

    2010-01-01

    This multifaceted work on chess played without sight of the pieces is a sophisticated psychologist's examination of this topic and of chess skill in general, including a detailed and comprehensive historical account. This review builds on Hearst and Knott's assertion that chess can provide a uniquely useful model for research on several issues in the area of cognitive skill and imagery. A key issue is the relationship between viewing a stimulus and mental imagery in the light of blindfold chess masters' consistent reports that they do not use or have images. This review also proposes a methodology for measuring and quantifying an individual's skill shortfall from a theoretical maximum. This methodology, based on a 1951 proposal by Claude Shannon, is applicable to any choice situation in which all the available choices are known. The proposed “Proficiency” measure reflects the equivalent number of “yes–no” questions that would have been required to arrive at a best choice, considering also the time consumed. As the measure provides a valid and nonarbitrary way to compare different skills and the effects of different independent variables on a given skill, it may have a wide range of applications in cognitive skill research, skill training, and education.

  3. Between phrén and psyché: Gabriele Buccola and his contribution to the birth of experimental psychology in Italy.

    PubMed

    Degni, Silvia

    2006-01-01

    The institution in 1880 of a laboratory of experimental psychology in the San Lazzaro Mental Hospital of Reggio Emilia, directed by Augusto Tamburini, marks a fundamental stage for the birth of scientific psychology in Italy. It was in this laboratory that the Sicilian psychiatrist Gabriele Buccola worked, carrying out reaction-time experiments in a broad and systematic way on "sane" and mentally ill individuals. In so doing, he was following Claude Bernard's lesson--which was advocated also by Comte, Taine, and Ribot, as in Italy by Livi and Tamburini-- according to which mental functions are to be studied in both normal and pathological conditions. With these experiments, Buccola highlighted the way in which reaction time is tied to "attention," how it is altered by mental illness, and how there are various "modifiers" that influence the results. He also shows how the measurement of this "time" represents an important instrument for the differential diagnosis of several mental pathologies. Buccola's work, which is implemented in the first volume of experimental psychology written in Italy, demonstrates how psychology, which in the second half of the nineteenth century aspired to become an autonomous science, developed in Italy from the root of psychiatry, on the common ground of evolutionary positivism.

  4. Overview of Air Liquide refrigeration systems between 1.8 K and 200 K

    SciTech Connect

    Gondrand, C.; Durand, F.; Delcayre, F.; Crispel, S.; Baguer, G. M. Gistau

    2014-01-29

    Cryogenic refrigeration systems are necessary for numerous applications. Gas purification and distillation require temperatures between 15 K and 200 K depending on the application, space simulation chambers down to 15 K, superconductivity between 1.8 K and up to 75 K (magnets, cavities or HTS devices like cables, FCL, SMES, etc), Cold Neutron Sources between 15 and 20 K, etc. Air Liquide Advanced Technologies is designing and manufacturing refrigerators since 60 years to satisfy those needs. The step by step developments achieved have led to machines with higher efficiency and reliability. In 1965, reciprocating compressors and Joule Thomson expansion valves were used. In 1969, centripetal expanders began to be used. In 1980, oil lubricated screw compressors took the place of reciprocating compressors and a standard range of Claude cycle refrigerators was developed: the HELIAL series. 1980 was also the time for cryogenic centrifugal compressor development. In 2011, driven by the need for lower operational cost (high efficiency and low maintenance), cycle oil free centrifugal compressors on magnetic bearings were introduced instead of screw compressors. The power extracted by centripetal expanders was recovered. Based on this technology, a range of Turbo-Brayton refrigerators has been designed for temperatures between 40 K and 150 K. On-going development will enable widening the range of Turbo-Brayton refrigerators to cryogenic temperatures down to 15 K.. Cryogenic centrifugal circulators have been developed in order to answer to an increasing demand of 4 K refrigerators able to distribute cold power.

  5. Narrating consciousness: language, media and embodiment.

    PubMed

    Hayles, N Katherine; Pulizzi, James J

    2010-01-01

    Although there has long been a division in studies of consciousness between a focus on neuronal processes or conversely an emphasis on the ruminations of a conscious self, the long-standing split between mechanism and meaning within the brain was mirrored by a split without, between information as a technical term and the meanings that messages are commonly thought to convey. How to heal this breach has posed formidable problems to researchers. Working through the history of cybernetics, one of the historical sites where Claude Shannon's information theory quickly became received doctrine, we argue that the cybernetic program as it developed through second-order cybernetics and autopoietic theory remains incomplete. In this article, we return to fundamental questions about pattern and noise, context and meaning, to forge connections between consciousness, narrative and media. The thrust of our project is to reintroduce context and narrative as crucial factors in the processes of meaning-making. The project proceeds along two fronts: advancing a theoretical framework within which context plays its property central role; and demonstrating the importance of context by analyzing two fictions, Stanislaw Lem's "His Master's Voice" and Joseph McElroy's "Plus," in which context has been deformed by being wrenched away from normal human environments, with radical consequences for processes of meaning-making.

  6. STS-103 perfect night-time landing for Space Shuttle Discovery

    NASA Technical Reports Server (NTRS)

    1999-01-01

    The orbiter Discovery looks like a blue ghost as it drops from the darkness onto lighted runway 33 at KSC's Shuttle Landing Facility. After traveling more than 3,267,000 miles on a successful eight-day mission to service the Hubble Space Telescope, the orbiter touches down at 7:00:47 p.m. EST. Aboard are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland and Jean-Frangois Clervoy of France, who spent the Christmas holiday in space in order to accomplish their mission before the end of 1999. During the mission, Discovery's four space-walking astronauts, Smith, Foale, Grunsfeld and Nicollier, spent 24 hours and 33 minutes upgrading and refurbishing Hubble, making it more capable than ever to renew its observations of the universe. Mission objectives included replacing gyroscopes and an old computer, installing another solid state recorder, and replacing damaged insulation in the telescope. Hubble was released from the end of Discovery's robot arm on Christmas Day. This was the 96th flight in the Space Shuttle program and the 27th for the orbiter Discovery. The landing was the 20th consecutive Shuttle landing in Florida and the 13th night landing in Shuttle program history.

  7. STS-103 MS Clervoy tries on oxygen mask

    NASA Technical Reports Server (NTRS)

    1999-01-01

    In the bunker at Launch Pad 39B, STS-103 Mission Specialist Jean-Frangois Clervoy of France, who is with the European Space Agency (ESA), tries on an oxygen mask during Terminal Countdown Demonstration Test (TCDT) activities. The TCDT provides the crew with emergency egress training, opportunities to inspect their mission payloads in the orbiter's payload bay, and simulated countdown exercises. Other crew members taking part are Commander Curtis L. Brown Jr. and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), plus Claude Nicollier of Switzerland, who is also with ESA. STS-103 is a 'call-up' mission due to the need to replace and repair portions of the Hubble Space Telescope, including the gyroscopes that allow the telescope to point at stars, galaxies and planets. The STS-103 crew will be replacing a Fine Guidance Sensor, an older computer with a new enhanced model, an older data tape recorder with a solid-state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The mission is targeted for launch Dec. 6 at 2:37 a.m. EST.

  8. STS-103 Pilot Scott Kelly and MS John Grunsfeld try on oxygen masks

    NASA Technical Reports Server (NTRS)

    1999-01-01

    In the bunker at Launch Pad 39B, STS-103 Pilot Scott J. Kelly (left) and Mission Specialist John M. Grunsfeld (Ph.D.) (right) try on oxygen masks during Terminal Countdown Demonstration Test (TCDT) activities. The TCDT provides the crew with emergency egress training, opportunities to inspect their mission payloads in the orbiter's payload bay, and simulated countdown exercises. Other crew members taking part are Commander Curtis L. Brown Jr. and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), and Jean-Frangois Clervoy of France and Claude Nicollier of Switzerland, who are with the European Space Agency. STS-103 is a 'call-up' mission due to the need to replace and repair portions of the Hubble Space Telescope, including the gyroscopes that allow the telescope to point at stars, galaxies and planets. The STS-103 crew will be replacing a Fine Guidance Sensor, an older computer with a new enhanced model, an older data tape recorder with a solid-state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The mission is targeted for launch Dec. 6 at 2:37 a.m. EST.

  9. The STS-103 crew with loved ones at Pad 39B

    NASA Technical Reports Server (NTRS)

    1999-01-01

    The STS-103 crew pose for photographers with their loved ones at Launch Pad 39B. Space Shuttle Discovery is in the background, next to the Fixed Service Structure lit up like a Christmas tree. Viewed left to right are Mission Specialist Steven L. Smith and his wife, Peggy; Pilot Scott J. Kelly and his wife, Leslie; Commander Curtis L. Brown Jr. and his fiancee, Ann Brickert; Mission Specialist C. Michael Foale; Laurence Clervoy and her husband, Mission Specialist Jean-Frangois Clervoy; Mission Specialist John M. Grunsfeld and his wife, Carol; Mission Specialist Claude Nicollier and his wife, Susana. Nicollier and Clervoy are with the European Space Agency. The mission, to service the Hubble Space Telescope, is scheduled for launch Dec. 17 at 8:47 p.m. EST from Launch Pad 39B. Mission objectives include replacing gyroscopes and an old computer, installing another solid state recorder, and replacing damaged insulation in the telescope. The mission is expected to last about 8 days and 21 hours. Discovery is expected to land at KSC Sunday, Dec. 26, at about 6:25 p.m. EST.

  10. STS-103 Mission Specialist Foale and his family DEPART PAFB for Houston

    NASA Technical Reports Server (NTRS)

    1999-01-01

    STS-103 Mission Specialist C. Michael Foale (Ph.D.) holds one of his children on the runway at Patrick Air Force Base in Cocoa Beach, Fla., as his wife, Rhonda, looks on. The STS-103 crew and their families are preparing to board an airplane that will return them to their home base at the Johnson Space Center in Houston following the successful completion of their mission. Discovery landed in darkness the previous evening, Dec. 27, on runway 33 at KSC's Shuttle Landing Facility at 7:00:47 p.m. EST. This was the first time that a Shuttle crew spent the Christmas holiday in space. The other STS-103 crew members are Commander Curtis L. Brown Jr.; Pilot Scott J. Kelly; and Mission Specialists Steven L. Smith, John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland and Jean-Frangois Clervoy of France. The STS-103 mission accomplished outfitting the Hubble Space Telescope with six new gyroscopes, six new voltage/temperature improvement kits, a new onboard computer, a new solid state recorder and new data transmitter, a new fine guidance sensor along with new insulation on parts of the orbiting telescope. This was the 96th flight in the Space Shuttle program and the 27th for the orbiter Discovery.

  11. STS-103 crew members and their families pose for a portrait before DEPARTing

    NASA Technical Reports Server (NTRS)

    1999-01-01

    The STS-103 crew pose for a group portrait with their families and loved ones on the runway at Patrick Air Force Base in Cocoa Beach, Fla. They are preparing to board an airplane that will return them to their home base at the Johnson Space Center in Houston following the successful completion of their mission. From left to right, the crew members are Mission Specialists John M. Grunsfeld (Ph.D.), C. Michael Foale (Ph.D.), Claude Nicollier of Switzerland, Jean-Frangois Clervoy of France, and Steven L. Smith; Pilot Scott J. Kelly; and Commander Curtis L. Brown Jr. Discovery landed in darkness the previous evening, Dec. 27, on runway 33 at KSC's Shuttle Landing Facility at 7:00:47 p.m. EST. This was the first time that a Shuttle crew spent the Christmas holiday in space. The STS-103 mission accomplished outfitting the Hubble Space Telescope with six new gyroscopes, six new voltage/temperature improvement kits, a new onboard computer, a new solid state recorder and new data transmitter, a new fine guidance sensor along with new insulation on parts of the orbiting telescope. This was the 96th flight in the Space Shuttle program and the 27th for the orbiter Discovery.

  12. STS-103 Mission Specialist Grunsfeld and his family DEPART PAFB for Houston

    NASA Technical Reports Server (NTRS)

    1999-01-01

    STS-103 Mission Specialist John M. Grunsfeld (Ph.D.), with his wife, Carol, and their children, smiles for the camera on the runway at Patrick Air Force Base in Cocoa Beach, Fla. The STS-103 crew and their families are preparing to board an airplane that will return them to their home base at the Johnson Space Center in Houston following the successful completion of their mission. Discovery landed in darkness the previous evening, Dec. 27, on runway 33 at KSC's Shuttle Landing Facility at 7:00:47 p.m. EST. This was the first time that a Shuttle crew spent the Christmas holiday in space. The other STS-103 crew members are Commander Curtis L. Brown Jr.; Pilot Scott J. Kelly; and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), Claude Nicollier of Switzerland and Jean-Frangois Clervoy of France. The STS-103 mission accomplished outfitting the Hubble Space Telescope with six new gyroscopes, six new voltage/temperature improvement kits, a new onboard computer, a new solid state recorder and new data transmitter, a new fine guidance sensor along with new insulation on parts of the orbiting telescope. This was the 96th flight in the Space Shuttle program and the 27th for the orbiter Discovery.

  13. Disaster mythology and fact: Hurricane Katrina and social attachment.

    PubMed

    Jacob, Binu; Mawson, Anthony R; Payton, Marinelle; Guignard, John C

    2008-01-01

    Misconceptions about disasters and their social and health consequences remain prevalent despite considerable research evidence to the contrary. Eight such myths and their factual counterparts were reviewed in a classic report on the public health impact of disasters by Claude de Ville de Goyet entitled, The Role of WHO in Disaster Management: Relief, Rehabilitation, and Reconstruction (Geneva, World Health Organization, 1991), and two additional myths and facts were added by Pan American Health Organization. In this article, we reconsider these myths and facts in relation to Hurricane Katrina, with particular emphasis on psychosocial needs and behaviors, based on data gleaned from scientific sources as well as printed and electronic media reports. The review suggests that preparedness plans for disasters involving forced mass evacuation and resettlement should place a high priority on keeping families together--and even entire neighborhoods, where possible--so as to preserve the familiar and thereby minimize the adverse effects of separation and major dislocation on mental and physical health.

  14. Overview of Air Liquide refrigeration systems between 1.8 K and 200 K

    NASA Astrophysics Data System (ADS)

    Gondrand, C.; Durand, F.; Delcayre, F.; Crispel, S.; Baguer, G. M. Gistau

    2014-01-01

    Cryogenic refrigeration systems are necessary for numerous applications. Gas purification and distillation require temperatures between 15 K and 200 K depending on the application, space simulation chambers down to 15 K, superconductivity between 1.8 K and up to 75 K (magnets, cavities or HTS devices like cables, FCL, SMES, etc), Cold Neutron Sources between 15 and 20 K, etc. Air Liquide Advanced Technologies is designing and manufacturing refrigerators since 60 years to satisfy those needs. The step by step developments achieved have led to machines with higher efficiency and reliability. In 1965, reciprocating compressors and Joule Thomson expansion valves were used. In 1969, centripetal expanders began to be used. In 1980, oil lubricated screw compressors took the place of reciprocating compressors and a standard range of Claude cycle refrigerators was developed: the HELIAL series. 1980 was also the time for cryogenic centrifugal compressor development. In 2011, driven by the need for lower operational cost (high efficiency and low maintenance), cycle oil free centrifugal compressors on magnetic bearings were introduced instead of screw compressors. The power extracted by centripetal expanders was recovered. Based on this technology, a range of Turbo-Brayton refrigerators has been designed for temperatures between 40 K and 150 K. On-going development will enable widening the range of Turbo-Brayton refrigerators to cryogenic temperatures down to 15 K.. Cryogenic centrifugal circulators have been developed in order to answer to an increasing demand of 4 K refrigerators able to distribute cold power.

  15. STS-46 post flight press conference

    NASA Astrophysics Data System (ADS)

    1992-08-01

    At a post flight press conference, the flight crew of the STS-46 mission (Cmdr. Loren Shriver, Pilot Andrew Allen, Mission Specialists Claude Nicollier (European Space Agency (ESA)), Marsha Ivins (Flight Engineer), Jeff Hoffman (Payload Commander), Franklin Chang-Dias, and Payload Specialist Franco Malerba (Italian Space Agency (ISA))) discussed their roles in and presented video footage, slides and still photographs of the different aspects of their mission. The primary objectives of the mission were the deployment of ESA's European Retrievable Carrier (EURECA) satellite and the joint NASA/ISA deployment and testing of the Tethered Satellite System (TSS). Secondary objectives included the IMAX Camera, the Limited Duration Space Environment Candidate Materials Exposure (LDVE), and the Pituitary Growth Hormone Cell Function (PHCF) experiments. Video footage of the EURECA and TSS deployment procedures are shown. Earth views were extensive and included Javanese volcanoes, Amazon basin forest ground fires, southern Mexico, southern Bolivian volcanoes, south-west Sudan and the Sahara Desert, and Melville Island, Australia. Questions from reporters and journalists from Johnson Space Center and Kennedy Space Center were discussed.

  16. Defective interactions of protein partner with ion channels and transporters as alternative mechanisms of membrane channelopathies.

    PubMed

    Kline, Crystal F; Mohler, Peter J

    2014-02-01

    The past twenty years have revealed the existence of numerous ion channel mutations resulting in human pathology. Ion channels provide the basis of diverse cellular functions, ranging from hormone secretion, excitation-contraction coupling, cell signaling, immune response, and trans-epithelial transport. Therefore, the regulation of biophysical properties of channels is vital in human physiology. Only within the last decade has the role of non-ion channel components come to light in regard to ion channel spatial, temporal, and biophysical regulation in physiology. A growing number of auxiliary components have been determined to play elemental roles in excitable cell physiology, with dysfunction resulting in disorders and related manifestations. This review focuses on the broad implications of such dysfunction, focusing on disease-causing mutations that alter interactions between ion channels and auxiliary ion channel components in a diverse set of human excitable cell disease. This article is part of a Special Issue entitled: Reciprocal influences between cell cytoskeleton and membrane channels, receptors and transporters. Guest Editor: Jean Claude Hervé

  17. The ion channels to cytoskeleton connection as potential mechanism of mechanosensitivity.

    PubMed

    Martinac, Boris

    2014-02-01

    As biological force-sensing systems mechanosensitive (MS) ion channels present the best example of coupling molecular dynamics of membrane proteins to the mechanics of the surrounding cell membrane. In animal cells MS channels have over the past two decades been very much in focus of mechanotransduction research. In recent years this helped to raise awareness of basic and medical researchers about the role that abnormal MS channels may play in the pathophysiology of diseases, such as cardiac hypertrophy, atrial fibrillation, muscular dystrophy or polycystic kidney disease. To date a large number of MS channels from organisms of diverse phylogenetic origins have been identified at the molecular level; however, the structure of only few of them has been determined. Although their function has extensively been studied in a great variety of cells and tissues by different experimental approaches it is, with exception of bacterial MS channels, very little known about how these channels sense mechanical force and which cellular components may contribute to their function. By focusing on MS channels found in animal cells this article discusses the ways in which the connections between cytoskeleton and ion channels may contribute to mechanosensory transduction in these cells. This article is part of a Special Issue entitled: Reciprocal influences between cell cytoskeleton and membrane channels, receptors and transporters. This article is part of a Special Issue entitled: Reciprocal influences between cell cytoskeleton and membrane channels, receptors and transporters. Guest Editor: Jean Claude Hervé.

  18. STS-103 Discovery launch from Pad 39-B

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Like a roman candle, Space Shuttle Discovery roars into the clear night sky trailing brilliant exhaust from the solid rocket boosters (center) and blue mach diamonds from the main engine nozzles. Liftoff occurred at 7:50 p.m. EST from Launch Pad 39B. On board are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland and Jean-Frangois Clervoy of France. Nicollier and Clervoy are with the European Space Agency. STS-103 is a Hubble Servicing Mission, with three planned space walks designed to install new equipment and replace old. The primary objective is to replace the gyroscopes that make up the three Rate Sensor Units. Extravehicular activities include installing a new computer, changing out one of the Fine Guidance Sensors, replacing a tape recorder with a new solid state recorder, and installing a voltage/temperature improvement kit, and begin repairing the insulation on the telescope's outer surface. After the 7-day, 21-hour mission, Discovery is expected to land at KSC Monday, Dec. 27, at about 5:24 p.m. EST. This is the 27th flight of Discovery and the 96th mission in the Space Shuttle Program. It is the third launch at Kennedy Space Center in 1999.

  19. STS-103 Mission Specialist Clervoy suits up before launch

    NASA Technical Reports Server (NTRS)

    1999-01-01

    After donning his launch and entry suit, STS-103 Mission Specialist Jean-Francois Clervoy of France gives two thumbs up to show he is ready for the second launch attempt of Space Shuttle Discovery. The previous launch attempt on Dec. 17 was scrubbed about 8:52 p.m. due to numerous violations of weather launch commit criteria at KSC. Clervoy and fellow crew members Commander Curtis L. Brown Jr., Pilot Scott J. Kelly and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.) and Claude Nicollier of Switzerland are scheduled to lift off at 7:50 p.m. EST Dec. 19 on mission STS-103, servicing the Hubble Space Telescope. Objectives for the nearly eight-day mission include replacing gyroscopes and an old computer, installing another solid state recorder, and replacing damaged insulation in the telescope. Discovery is expected to land at KSC Monday, Dec. 27, at about 5:24 p.m. EST.

  20. STS-103 Discovery launch from Pad 39-B

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Liftoff of Space Shuttle Discovery leaves Launch Pad 39B (seen at right) and Earth behind, lighted by the brilliant exhaust of the solid rocket boosters and external tank. Liftoff occurred at 7:50 p.m. EST from Launch Pad 39B. On board are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland and Jean-Frangois Clervoy of France. Nicollier and Clervoy are with the European Space Agency. STS-103 is a Hubble Servicing Mission, with three planned space walks designed to install new equipment and replace old. The primary objective is to replace the gyroscopes that make up the three Rate Sensor Units. Extravehicular activities include installing a new computer, changing out one of the Fine Guidance Sensors, replacing a tape recorder with a new solid state recorder, and installing a voltage/temperature improvement kit, and begin repairing the insulation on the telescope's outer surface. After the 7-day, 21-hour mission, Discovery is expected to land at KSC Monday, Dec. 27, at about 5:24 p.m. EST. This is the 27th flight of Discovery and the 96th mission in the Space Shuttle Program. It is the third launch at Kennedy Space Center in 1999.

  1. STS-103 Discovery launch from Pad 39-B

    NASA Technical Reports Server (NTRS)

    1999-01-01

    As if spawned by the clouds of smoke and steam below, the Space Shuttle Discovery shoots into the night sky on mission STS-103. The brilliant light creates a reflection of the launch in the water nearby. Liftoff occurred at 7:50 p.m. EST from Launch Pad 39B. On board are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland and Jean-Frangois Clervoy of France. Nicollier and Clervoy are with the European Space Agency. STS-103 is a Hubble Servicing Mission, with three planned space walks designed to install new equipment and replace old. The primary objective is to replace the gyroscopes that make up the three Rate Sensor Units. Extravehicular activities include installing a new computer, changing out one of the Fine Guidance Sensors, replacing a tape recorder with a new solid state recorder, and installing a voltage/temperature improvement kit, and begin repairing the insulation on the telescope's outer surface. After the 7-day, 21-hour mission, Discovery is expected to land at KSC Monday, Dec. 27, at about 5:24 p.m. EST. This is the 27th flight of Discovery and the 96th mission in the Space Shuttle Program. It is the third launch at Kennedy Space Center in 1999.

  2. STS-103 Mission Specialist Foale suits up before launch.

    NASA Technical Reports Server (NTRS)

    1999-01-01

    STS-103 Mission Specialist C. Michael Foale (Ph.D.) dons his launch and entry suit for the second time in two days before heading out to Launch Pad 39B and liftoff of Space Shuttle Discovery. The previous launch attempt on Dec. 17 was scrubbed about 8:52 p.m. due to numerous violations of weather launch commit criteria at KSC. Foale and other crew members Commander Curtis L. Brown Jr., Pilot Scott J. Kelly and Mission Specialists Steven L. Smith, John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland and Jean-Francois Clervoy of France are scheduled to lift off at 7:50 p.m. EST Dec. 19 on mission STS-103, servicing the Hubble Space Telescope. Objectives for the nearly eight-day mission include replacing gyroscopes and an old computer, installing another solid state recorder, and replacing damaged insulation in the telescope. Discovery is expected to land at KSC Monday, Dec. 27, at about 5:24 p.m. EST.

  3. STS-103 Discovery launch from Pad 39-B

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Viewed from the roof of the Vehicle Assembly Building more than 3 miles away, the launch of Space Shuttle Discovery on mission STS-103 emblazes the night sky. Liftoff occurred at 7:50 p.m. EST from Launch Pad 39B. On board are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland and Jean-Frangois Clervoy of France. Nicollier and Clervoy are with the European Space Agency. STS-103 is a Hubble Servicing Mission, with three planned space walks designed to install new equipment and replace old. The primary objective is to replace the gyroscopes that make up the three Rate Sensor Units. Extravehicular activities include installing a new computer, changing out one of the Fine Guidance Sensors, replacing a tape recorder with a new solid state recorder, and installing a voltage/temperature improvement kit, and begin repairing the insulation on the telescope's outer surface. After the 7-day, 21-hour mission, Discovery is targeted to land at KSC Monday, Dec. 27, at about 5:24 p.m. EST. This is the 27th flight of Discovery and the 96th mission in the Space Shuttle Program. It is the third launch at Kennedy Space Center in 1999.

  4. STS-103 Mission Specialist Smith suits up before launch

    NASA Technical Reports Server (NTRS)

    1999-01-01

    After donning his launch and entry suit, sts-103 Mission Specialist Steven L. Smith shows a positive attitude over the second launch attempt for Space Shuttle Discovery. The previous launch attempt on Dec. 17 was scrubbed about 8:52 p.m. due to numerous violations of weather launch commit criteria at KSC. Smith and other crew members Commander Curtis L. Brown Jr., Pilot Scott J. Kelly and Mission Specialists C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland and Jean-Francois Clervoy of France are scheduled to lift off at 7:50 p.m. EST Dec. 19 on mission STS-103, servicing the Hubble Space Telescope. Objectives for the nearly eight-day mission include replacing gyroscopes and an old computer, installing another solid state recorder, and replacing damaged insulation in the telescope. Discovery is expected to land at KSC Monday, Dec. 27, at about 5:24 p.m. EST.

  5. STS-103 Discovery launch from Pad 39-B

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Space Shuttle Discovery hurtles through clouds of smoke and steam in its successful launch on mission STS-103. Liftoff occurred at 7:50 p.m. EST from Launch Pad 39B. On board are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland and Jean-Frangois Clervoy of France. Nicollier and Clervoy are with the European Space Agency. STS-103 is a Hubble Servicing Mission, with three planned space walks designed to install new equipment and replace old. The primary objective is to replace the gyroscopes that make up the three Rate Sensor Units. Extravehicular activities include installing a new computer, changing out one of the Fine Guidance Sensors, replacing a tape recorder with a new solid state recorder, and installing a voltage/temperature improvement kit, and begin repairing the insulation on the telescope's outer surface. After the 7-day, 21-hour mission, Discovery is targeted to land at KSC Monday, Dec. 27, at about 5:24 p.m. EST. This is the 27th flight of Discovery and the 96th mission in the Space Shuttle Program. It is the third launch at Kennedy Space Center in 1999.

  6. STS-103 crew show eagerness to get to Launch Pad 39B for launch

    NASA Technical Reports Server (NTRS)

    1999-01-01

    The STS-103 crew in their launch and entry suits signal confidence as they head out of the Operations and Checkout Building, for the second time in two days, on their way to Launch Pad 39B and liftoff of Space Shuttle Discovery. From front to back by two's are Pilot Scott J. Kelly and Commander Curtis L. Brown Jr., Mission Specialists John M. Grunsfeld (Ph.D.) and Jean-Francois Clervoy of France, C. Michael Foale (Ph.D.) and Claude Nicollier of Switzerland, and Steven L. Smith taking up the rear. The previous launch attempt on Dec. 17 was scrubbed about 8:52 p.m. due to numerous violations of weather launch commit criteria at KSC. The mission, to service the Hubble Space Telescope, is now scheduled for launch Dec. 19 at 7:50 p.m. EST from Launch Pad 39B. Mission objectives include replacing gyroscopes and an old computer, installing another solid state recorder, and replacing damaged insulation in the telescope. After the 7-day, 21-hour mission, Discovery is expected to land at KSC Monday, Dec. 27, at about 5:24 p.m. EST.

  7. STS-103 Discovery launch from Pad 39-B

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Turning night into day for a few moments while belching clouds of smoke and steam, Space Shuttle Discovery hurtles into the black sky on mission STS-103. The successful liftoff occurred at 7:50 p.m. EST from Launch Pad 39B. On board are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland and Jean-Frangois Clervoy of France. Nicollier and Clervoy are with the European Space Agency. STS-103 is a Hubble Servicing Mission, with three planned space walks designed to install new equipment and replace old. The primary objective is to replace the gyroscopes that make up the three Rate Sensor Units. Extravehicular activities include installing a new computer, changing out one of the Fine Guidance Sensors, replacing a tape recorder with a new solid state recorder, and installing a voltage/temperature improvement kit, and begin repairing the insulation on the telescope's outer surface. After the 7-day, 21-hour mission, Discovery is targeted to land at KSC Monday, Dec. 27, at about 5:24 p.m. EST. This is the 27th flight of Discovery and the 96th mission in the Space Shuttle Program. It is the third launch at Kennedy Space Center in 1999.

  8. STS-103 Discovery launch from Pad 39-B

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Turning night into day, the brilliance of Space Shuttle Discovery's launch is reflected in the waters nearby. Liftoff occurred at 7:50 p.m. EST from Launch Pad 39B. On board are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland and Jean-Frangois Clervoy of France. Nicollier and Clervoy are with the European Space Agency. STS-103 is a Hubble Servicing Mission, with three planned space walks designed to install new equipment and replace old. The primary objective is to replace the gyroscopes that make up the three Rate Sensor Units. Extravehicular activities include installing a new computer, changing out one of the Fine Guidance Sensors, replacing a tape recorder with a new solid state recorder, and installing a voltage/temperature improvement kit, and begin repairing the insulation on the telescope's outer surface. After the 7-day, 21-hour mission, Discovery is expected to land at KSC Monday, Dec. 27, at about 5:24 p.m. EST. This is the 27th flight of Discovery and the 96th mission in the Space Shuttle Program. It is the third launch at Kennedy Space Center in 1999.

  9. STS-103 Discovery launch from Pad 39-B

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Brilliant light from the successful liftoff of Space Shuttle Discovery on mission STS-103 illuminates the night sky and the nearby waters. Liftoff occurred at 7:50 p.m. EST from Launch Pad 39B. On board are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland and Jean-Frangois Clervoy of France. Nicollier and Clervoy are with the European Space Agency. STS-103 is a Hubble Servicing Mission, with three planned space walks designed to install new equipment and replace old. The primary objective is to replace the gyroscopes that make up the three Rate Sensor Units. Extravehicular activities include installing a new computer, changing out one of the Fine Guidance Sensors, replacing a tape recorder with a new solid state recorder, and installing a voltage/temperature improvement kit, and begin repairing the insulation on the telescope's outer surface. After the 7-day, 21-hour mission, Discovery is expected to land at KSC Monday, Dec. 27, at about 5:24 p.m. EST. This is the 27th flight of Discovery and the 96th mission in the Space Shuttle Program. It is the third launch at Kennedy Space Center in 1999.

  10. STS-103 crew eager for ride to Launch Pad 39B for launch

    NASA Technical Reports Server (NTRS)

    1999-01-01

    An eager STS-103 crew emerge from behind the 'Astrovan' at the Operations and Checkout Building to board the vehicle for transfer to Launch Pad 39B. Walking in pairs (from front to back) are Pilot Scott J. Kelly and Commander Curtis L. Brown Jr., Mission Specialists John M. Grunsfeld (Ph.D.) and Jean-Francois Clervoy of France, C. Michael Foale (Ph.D.) and Claude Nicollier of Switzerland, and Steven L. Smith taking up the rear. A previous launch attempt on Dec. 17 was scrubbed about 8:52 p.m. due to numerous violations of weather launch commit criteria at KSC. The mission, to service the Hubble Space Telescope, is now scheduled for launch Dec. 19 at 7:50 p.m. EST from Launch Pad 39B. Mission objectives include replacing gyroscopes and an old computer, installing another solid state recorder, and replacing damaged insulation in the telescope. After the 7-day, 21-hour mission, Discovery is expected to land at KSC Monday, Dec. 27, at about 5:24 p.m. EST.

  11. STS-103 Discovery launch from Pad 39-B

    NASA Technical Reports Server (NTRS)

    1999-01-01

    The successful liftoff of Space Shuttle Discovery on mission STS-103 illuminates the night sky. Liftoff occurred at 7:50 p.m. EST from Launch Pad 39B. On board are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland and Jean-Frangois Clervoy of France. Nicollier and Clervoy are with the European Space Agency. STS-103 is a Hubble Servicing Mission, with three planned space walks designed to install new equipment and replace old. The primary objective is to replace the gyroscopes that make up the three Rate Sensor Units. Extravehicular activities include installing a new computer, changing out one of the Fine Guidance Sensors, replacing a tape recorder with a new solid state recorder, and installing a voltage/temperature improvement kit, and begin repairing the insulation on the telescope's outer surface. After the 7-day, 21-hour mission, Discovery is expected to land at KSC Monday, Dec. 27, at about 5:24 p.m. EST. This is the 27th flight of Discovery and the 96th mission in the Space Shuttle Program. It is the third launch at Kennedy Space Center in 1999.

  12. The STS-103 crew have breakfast before launch

    NASA Technical Reports Server (NTRS)

    1999-01-01

    For the second time in two days, the STS-103 crew have breakfast before suiting up for launch. From left are Mission Specialists Claude Nicollier of Switzerland and C. Michael Foale (Ph.D.), Pilot Scott J. Kelly, Commander Curtis L. Brown Jr., and Mission Specialists Jean-Francois Clervoy of France, John M. Grunsfeld (Ph.D.) and Steven L. Smith. Nicollier and Clervoy are with the European Space Agency. The previous launch attempt on Dec. 17 was scrubbed about 8:52 p.m. due to numerous violations of weather launch commit criteria at KSC. The mission, to service the Hubble Space Telescope, is now scheduled for launch Dec. 19 at 7:50 p.m. EST from Launch Pad 39B. Mission objectives include replacing gyroscopes and an old computer, installing another solid state recorder, and replacing damaged insulation in the telescope. After the 7-day, 21-hour mission, Discovery is expected to land at KSC Monday, Dec. 27, at about 5:24 p.m. EST.

  13. STS-103 Mission Specialist Nicollier suits up before launch

    NASA Technical Reports Server (NTRS)

    1999-01-01

    After donning his launch and entry suit, a grinning STS-103 Mission Specialist Claude Nicollier of Switzerland signals he is ready for the second launch attempt of Space Shuttle Discovery. The previous launch attempt on Dec. 17 was scrubbed about 8:52 p.m. due to numerous violations of weather launch commit criteria at KSC. Nicollier and fellow crew members Commander Curtis L. Brown Jr., Pilot Scott J. Kelly and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.) and Jean-Francois Clervoy of France are scheduled to lift off at 7:50 p.m. EST Dec. 19 on mission STS-103, servicing the Hubble Space Telescope. Objectives for the nearly eight-day mission include replacing gyroscopes and an old computer, installing another solid state recorder, and replacing damaged insulation in the telescope. Discovery is expected to land at KSC Monday, Dec. 27, at about 5:24 p.m. EST.

  14. STS-103 Discovery launch from Pad 39-B

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Brilliant light from the successful liftoff of Space Shuttle Discovery on mission STS-103 illuminates the night sky and reflects in the nearby water. Liftoff occurred at 7:50 p.m. EST from Launch Pad 39B. On board are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland and Jean-Frangois Clervoy of France. Nicollier and Clervoy are with the European Space Agency. STS-103 is a Hubble Servicing Mission, with three planned space walks designed to install new equipment and replace old. The primary objective is to replace the gyroscopes that make up the three Rate Sensor Units. Extravehicular activities include installing a new computer, changing out one of the Fine Guidance Sensors, replacing a tape recorder with a new solid state recorder, and installing a voltage/temperature improvement kit, and begin repairing the insulation on the telescope's outer surface. After the 7-day, 21-hour mission, Discovery is expected to land at KSC Monday, Dec. 27, at about 5:24 p.m. EST. This is the 27th flight of Discovery and the 96th mission in the Space Shuttle Program. It is the third launch at Kennedy Space Center in 1999.

  15. [On the evolution of scientific thought].

    PubMed

    de Micheli, Alfredo; Iturralde Torres, Pedro

    2015-01-01

    The Nominalists of the XIV century, precursors of modern science, thought that science's object was not the general, vague and indeterminate but the particular, which is real and can be known directly. About the middle of the XVII Century the bases of the modern science became established thanks to a revolution fomented essentially by Galileo, Bacon and Descartes. During the XVIII Century, parallel to the development of the great current of English Empiricism, a movement of scientific renewal also arose in continental Europe following the discipline of the Dutch Physicians and of Boerhaave. In the XIX Century, Claude Bernard dominated the scientific medicine but his rigorous determinism impeded him from taking into account the immense and unforeseeable field of the random. Nowadays, we approach natural science and medicine, from particular groups of facts; that is, from the responses of Nature to specific questions, but not from the general laws. Furthermore, in recent epistemology, the concept that experimental data are not pure facts, but rather, facts interpreted within a hermeneutical context has been established. Finally a general tendency to retrieve philosophical questions concerning the understanding of essence and existence can frequently be seen in scientific inquiry. In the light of the evolution of medical thought, it is possible to establish the position of scientific medicine within the movement of ideas dominating in our time.

  16. Neuromuscular block.

    PubMed

    Bowman, W C

    2006-01-01

    Descriptions of the South American arrow poisons known as curares were reported by explorers in the 16th century, and their site of action in producing neuromuscular block was determined by Claude Bernard in the mid-19th century. Tubocurarine, the most important curare alkaloid, played a large part in experiments to determine the role of acetylcholine in neuromuscular transmission, but it was not until after 1943 that neuromuscular blocking drugs became established as muscle relaxants for use during surgical anaesthesia. Tubocurarine causes a number of unwanted effects, and there have been many attempts to replace it. The available drugs fall into two main categories: the depolarising blocking drugs and the nondepolarising blocking drugs. The former act by complex mixed actions and are now obsolete with the exception of suxamethonium, the rapid onset and brief duration of action of which remain useful for intubation at the start of surgical anaesthesia. The nondepolarising blocking drugs are reversible acetylcholine receptor antagonists. The main ones are the atracurium group, which possess a built-in self-destruct mechanism that makes them specially useful in kidney or liver failure, and the vecuronium group, which are specially free from unwanted side effects. Of this latter group, the compound rocuronium is of special interest because its rapid onset of action allows it to be used for intubation, and there is promise that its duration of action may be rapidly terminated by a novel antagonist, a particular cyclodextrin, that chelates the drug, thereby removing it from the acetylcholine receptors.

  17. Kidney and urologic disorders in the age of enlightenment.

    PubMed

    Chevalier, R L

    1994-01-01

    The Enlightenment, a unique period in the history of Europe, was founded in the scientific and intellectual revolution of the 17th century. Renal anatomy and physiology advanced through the work of men like Eustachio, Malpighi, von Rosenstein and Cotugno, who described both normal and pathologic structures. Despite the earlier discovery of renal tubules and glomeruli, their anatomic and physiologic relationship remained unclear during the 18th century. The definitive explanation would not come until the work of Bowman and Bright in the 19th century. Similarly, the role of renal nerves would not emerge until the 19th century, when Claude Bernard elucidated their role in controlling urine flow in the dog. A key figure was Morgagni (1682-1771), who provided highly precise descriptions of a number of urinary tract anomalies and forms of obstructive nephropathy and developed many insights into renal pathophysiology by pure deductive reasoning. He gave a remarkably accurate description of the basis of reflux nephropathy and recognized that urinary calculi could have many etiologies. Lithotomy was performed as a last resort, and Cheselden reduced the mortality to 17% with a perineal approach; Baseilhac designed a new instrument to facilitate the suprapubic approach. Despite the high quality of men such as Morgagni, physicians had a reputation for quackery and rapacity, and most of their efforts met with little success.

  18. The accentuation principle of figure-ground segregation and the downbeat illusion.

    PubMed

    Pinna, Baingio; Sirigu, Luca

    2016-10-01

    Pinna and Sirigu (2011) demonstrated a new principle of grouping, called the accentuation principle, stating that, all else being equal, elements tend to group in the same oriented direction of the discontinuous element placed within a whole set of continuous/homogeneous components. The discontinuous element behaves like an accent, i.e. a visual emphasis within the wholeness of components as shown in the next section. In this work, the accentuation principle has been extended to new visual domains. In particular, it is shown how this principle affects shape perception. Moreover several visual object attributes are also highlighted, among which orientation, spatial position, inner dynamics and apparent motion that determine the so-called organic segmentation and furthermore tend to induce figure-ground segregation. On the basis of the results of experimental phenomenology, the accentuation can be considered as a complex principle ruling grouping, figure-ground segregation, shape and meaning formation. Through a new musical illusion of downbeat, it is also demonstrated that this principle influences perceptual organization not only in space but also in time and, thus, in both visual and musical domains. This illusion can be heard in eight measures of Pagodes, a solo piano music by Claude Debussy (1862-1918), where a strong physical-perceptual discrepancy in terms of upbeats and downbeats inversion is strongly perceived in both staves.

  19. Milestones in the history of diabetes mellitus: The main contributors

    PubMed Central

    Karamanou, Marianna; Protogerou, Athanase; Tsoucalas, Gregory; Androutsos, George; Poulakou-Rebelakou, Effie

    2016-01-01

    Diabetes mellitus is a group of metabolic diseases involving carbohydrate, lipid, and protein metabolism. It is characterized by persistent hyperglycemia which results from defects in insulin secretion, or action or both. Diabetes mellitus has been known since antiquity. Descriptions have been found in the Egyptian papyri, in ancient Indian and Chinese medical literature, as well as, in the work of ancient Greek and Arab physicians. In the 2nd century AD Aretaeus of Cappadocia provided the first accurate description of diabetes, coining the term diabetes, while in 17th century Thomas Willis added the term mellitus to the disease, in an attempt to describe the extremely sweet taste of the urine. The important work of the 19th century French physiologist Claude Bernard, on the glycogenic action of the liver, paved the way for further progress in the study of the disease. In 1889, Oskar Minkowski and Joseph von Mering performed their famous experiment of removing the pancreas from a dog and producing severe and fatal diabetes. In 1921, Frederick Banting and Charles Best extended Minkowski’s and Mering’s experiment. They isolated insulin from pancreatic islets and administrated to patients suffering from type 1 diabetes, saving thus the lives of millions and inaugurating a new era in diabetes treatment. PMID:26788261

  20. The renaissance of Peiresc: Aubin-Louis Millin and the postrevolutionary republic of letters.

    PubMed

    Adkins, G Matthew

    2008-12-01

    This essay argues for the emergence of a cultural and epistemological divide between amateur savants and members of the Royal Academy of the Sciences in late Old Regime and revolutionary France and suggests that the amateur ideal rose in significance even as intellectual activity came to be increasingly centralized in the postrevolutionary era. At the crux of the tensions between the amateur ideal and the professionalizing reality in the immediate postrevolutionary period stood Aubin-Louis Millin and his journal, the Magasin Encyclopédique. The essay examines, in particular, the revival in the pages of the Magasin Encyclopédique of interest in Nicolas-Claude Fabri de Peiresc, the seventeenth-century icon of an amateur ideal in which investigations in the natural sciences and scholarship were private, decentralized, often provincial activities. Although the sciences in the revolutionary and Napoleonic eras were often perceived as forward looking and dismissive of the past, this essay finds that a sentimental and nostalgic attachment to the past-to a myth of Peiresc-continued to play an important role in the identity of postrevolutionary men of letters.

  1. The history of cardiac catheterization.

    PubMed

    Bourassa, Martial G

    2005-10-01

    The evolution of cardiac catheterization has occurred over at least four centuries. One of the first major steps was the description of the circulation of the blood by William Harvey in 1628. The next milestone was the measurement of arterial pressure by Stephen Hales, one century later. However, the 19th century represented the golden age of cardiovascular physiology, highlighted by the achievements of Carl Ludwig, Etienne-Jules Marey and Claude Bernard, among others. Human cardiac catheterization developed during the 20th century. The first right heart catheterization in a human was performed by Werner Forssmann on himself in 1929. Diagnostic cardiac catheterization was introduced by André Cournand and Dickinson Richards in the early 1940s, and selective coronary angiography was described by Mason Sones in the early 1960s. More recently, with the advent of catheter-based interventions, pioneered by Andreas Gruentzig in the late 1970s, there has been considerable progress in the refinement and expansion of these techniques. Currently, the Sones technique is used only infrequently, and coronary angiography and percutaneous coronary intervention rely mainly on percutaneous femoral and percutaneous radial artery approaches. On the occasion of the 50th anniversary of the Montreal Heart Institute, it seems appropriate to highlight the contribution of this institution in these two areas.

  2. Ocean energy conversion systems annual research report

    SciTech Connect

    Not Available

    1981-03-01

    Alternative power cycle concepts to the closed-cycle Rankine are evaluated and those that show potential for delivering power in a cost-effective and environmentally acceptable fashion are explored. Concepts are classified according to the ocean energy resource: thermal, waves, currents, and salinity gradient. Research projects have been funded and reported in each of these areas. The lift of seawater entrained in a vertical steam flow can provide potential energy for a conventional hydraulic turbine conversion system. Quantification of the process and assessment of potential costs must be completed to support concept evaluation. Exploratory development is being completed in thermoelectricity and 2-phase nozzles for other thermal concepts. Wave energy concepts are being evaluated by analysis and model testing with present emphasis on pneumatic turbines and wave focussing. Likewise, several conversion approaches to ocean current energy are being evaluated. The use of salinity resources requires further research in membranes or the development of membraneless processes. Using the thermal resource in a Claude cycle process as a power converter is promising, and a program of R and D and subsystem development has been initiated to provide confirmation of the preliminary conclusion.

  3. Developing computer-based training programs for basic mammalian histology: Didactic versus discovery-based design

    NASA Astrophysics Data System (ADS)

    Fabian, Henry Joel

    Educators have long tried to understand what stimulates students to learn. The Swiss psychologist and zoologist, Jean Claude Piaget, suggested that students are stimulated to learn when they attempt to resolve confusion. He reasoned that students try to explain the world with the knowledge they have acquired in life. When they find their own explanations to be inadequate to explain phenomena, students find themselves in a temporary state of confusion. This prompts students to seek more plausible explanations. At this point, students are primed for learning (Piaget 1964). The Piagetian approach described above is called learning by discovery. To promote discovery learning, a teacher must first allow the student to recognize his misconception and then provide a plausible explanation to replace that misconception (Chinn and Brewer 1993). One application of this method is found in the various learning cycles, which have been demonstrated to be effective means for teaching science (Renner and Lawson 1973, Lawson 1986, Marek and Methven 1991, and Glasson & Lalik 1993). In contrast to the learning cycle, tutorial computer programs are generally not designed to correct student misconceptions, but rather follow a passive, didactic method of teaching. In the didactic or expositional method, the student is told about a phenomenon, but is neither encouraged to explore it, nor explain it in his own terms (Schneider and Renner 1980).

  4. Ethical Implications of the Mild Encephalitis Hypothesis of Schizophrenia

    PubMed Central

    Riedmüller, Rita; Müller, Sabine

    2017-01-01

    Schizophrenia is a serious mental disease with a high mortality rate and severe social consequences. Due to insufficient knowledge about its etiopathogenesis, curative treatments are not available. One of the most promising new research concepts is the mild encephalitis hypothesis of schizophrenia, developed mainly by Karl Bechter and Norbert Müller. According to this hypothesis, a significant subgroup of schizophrenia patients suffer from a mild, but chronic, form of encephalitis with markedly different etiologies ranging from viral infections, traumas to autoimmune diseases. This inflammatory process is thought to occur in the beginning or during the course of the disease. In this article, we investigate the consequences of the mild encephalitis hypothesis of schizophrenia for the scientific community, and evaluate these consequences ethically. The mild encephalitis hypothesis implies that schizophrenia would no longer be considered an incurable psychiatric disorder. Instead, it would be considered a chronic, but treatable, neurological disease. This paradigm shift would doubtlessly have significant consequences: (1) major reforms would be necessary in the theoretical conceptualization of schizophrenia, which would challenge the psychiatric diagnostic systems, Diagnostic and Statistical Manual of Mental Disorders version 5 and ICD-10. (2) Psychotic patients should be treated in interdisciplinary teams, optimally in neuropsychiatric units; additionally, specialists for endocrinology, diabetology, and cardiology should be consulted for the frequently occuring somatic comorbidities. (3) Current diagnostic procedures and (4) therapies would have to be modified significantly. (5) There might be repercussions for the pharmaceutical industry as well: first, because old drugs with expired patent protection could partly replace expensive drugs and, second, because there would be a demand for the development of new anti-inflammatory drugs. (6) Legal evaluation of

  5. Bavarian Prime Minister to Visit la Silla

    NASA Astrophysics Data System (ADS)

    1997-03-01

    The Bavarian Prime Minister, Dr. Edmund Stoiber , is currently visiting a number of countries in South America. He is accompanied by a high-ranking delegation of representatives of Bavarian politics and industry. During this trip, the Bavarian delegation will visit the Republic of Chile, arriving in Santiago de Chile on Sunday, March 9, 1997. On the same day, Dr. Stoiber and most other members of the delegation, on the invitation of the Director General of ESO, Professor Riccardo Giacconi, will visit the ESO La Silla Observatory , located in an isolated area in the Atacama desert some 600 km north of the Chilean capital. ESO, the European Organisation for Astronomy, with Headquarters in Garching near Munich in Bavaria, welcomes this opportunity to present its high-tech research facilities to Dr. Stoiber and leaders of the Bavarian industry. During the visit, the delegation will learn about the various front-line research projects, now being carried out by astronomers from Germany and other ESO member countries with the large telescopes at La Silla. There will also be a presentation of the ESO VLT project , which will become the world's largest optical astronomical telescope, when it is ready a few years from now. The delegation will be met by the Director of the La Silla Observatory, Dr. Jorge Melnick and his scientific-technical staff which includes several members of German nationality. Also present will be ESO's Head of Administration, Dr. Norbert König (Garching) and the General Manager of ESO in Chile, Mr. Daniel Hofstadt. More information about this visit and the ESO facilities is available from the ESO Education and Public Relations Department (Tel.: +49-89-32006-276; Fax.: +49-89-3202362; email: ips@eso.org; Web: http://www.eso.org../../../epr/ ). Diese Pressemitteilung ist auch in einer Deutschen Fassung vorhanden. How to obtain ESO Press Information ESO Press Information is made available on the World-Wide Web (URL: http://www.eso.org../). ESO Press

  6. ESPAS: the European e-science platform to access near-Earth space data (Invited)

    NASA Astrophysics Data System (ADS)

    Belehaki, A.; Hapgood, M. A.; Ritschel, B.; Manola, N.

    2013-12-01

    Lebesis, Bruno Zolesi, Tatjana Gerzen, Ingemar Häggström, Anna Charisi, Ivan Galkin, Jurgen Watermann, Matthew Angling, Timo Asikainen, Alan Aylward, Henrike Barkmann, Peter Bergqvist, Andrew Bushell, Fabien Darrouzet, Dimitris Dialetis, Carl-Fredrik Enell, Daniel Heynderickx, Norbert Jakowski, Magnar Johnsen, Jean Lilensten, Ian McCrea, Kalevi Mursula, Bogdan Nicula, Michael Pezzopane, Viviane Pierrard, Bodo Reinisch, Bernd Ritschel, Luca Spogli, Iwona Stanislawska, Claudia Stolle, Eija Tanskanen, Ioanna Tsagouri, Esa Turunen, Thomas Ulich, Matthew Wild, Tim Yeoman

  7. A distributed control approach for power and energy management in a notional shipboard power system

    NASA Astrophysics Data System (ADS)

    Shen, Qunying

    The main goal of this thesis is to present a power control module (PCON) based approach for power and energy management and to examine its control capability in shipboard power system (SPS). The proposed control scheme is implemented in a notional medium voltage direct current (MVDC) integrated power system (IPS) for electric ship. To realize the control functions such as ship mode selection, generator launch schedule, blackout monitoring, and fault ride-through, a PCON based distributed power and energy management system (PEMS) is developed. The control scheme is proposed as two-layer hierarchical architecture with system level on the top as the supervisory control and zonal level on the bottom as the decentralized control, which is based on the zonal distribution characteristic of the notional MVDC IPS that was proposed as one of the approaches for Next Generation Integrated Power System (NGIPS) by Norbert Doerry. Several types of modules with different functionalities are used to derive the control scheme in detail for the notional MVDC IPS. Those modules include the power generation module (PGM) that controls the function of generators, the power conversion module (PCM) that controls the functions of DC/DC or DC/AC converters, etc. Among them, the power control module (PCON) plays a critical role in the PEMS. It is the core of the control process. PCONs in the PEMS interact with all the other modules, such as power propulsion module (PPM), energy storage module (ESM), load shedding module (LSHED), and human machine interface (HMI) to realize the control algorithm in PEMS. The proposed control scheme is implemented in real time using the real time digital simulator (RTDS) to verify its validity. To achieve this, a system level energy storage module (SESM) and a zonal level energy storage module (ZESM) are developed in RTDS to cooperate with PCONs to realize the control functionalities. In addition, a load shedding module which takes into account the reliability

  8. Current Events via Electronic Media: An Instructional Tool in a General Education Geology Course

    NASA Astrophysics Data System (ADS)

    Flood, T. P.

    2008-12-01

    St. Norbert College (SNC) is a liberal arts college in the Green Bay Metropolitan area with an enrollment of approximately 2100 students. All students are required to take one science course with a laboratory component as part of the general education program. Approximately 40% of all SNC students take introductory geology. Class size for this course is approximately 35 students. Each faculty member teaches one section per semester in a smart classroom A synthesis of current events via electronic media is an excellent pedagogical tool for the introductory geology course. An on-going informal survey of my introductory geology class indicates that between 75- 85% of all students in the class, mostly freshman and sophomores, do not follow the news on a regular basis in any format, i.e. print, internet, or television. Consequently, most are unaware of current scientific topics, events, trends, and relevancy. To address this issue, and develop a positive habit of the mind, a technique called In-the-News-Making-News (INMN) is employed. Each class period begins with a scientifically-related (mostly geology) online news article displayed on an overhead screen. The articles are drawn from a variety of sources that include international sites such as the BBC and CBC; national sites such as PBS, New York Times, and CNN; and local sites such as the Milwaukee Journal Sentinel and the Green Bay Press Gazette. After perusing the article, additional information is often acquired by "Google" to help supplement and clarify the original article. An interactive discussion follows. Topics that are typically covered include: global climate change, basic scientific and technological discoveries, paleontology/evolution, natural disasters, mineral/ energy/ water resources, funding for science, space exploration, and other. Ancillary areas that are often touched on in the conversation include ethics, politics, economics, philosophy, education, geography, culture, or other. INMN addresses

  9. Galileo in-situ dust measurements and the significance of planetary shadowing in shaping Jupiter's gossamer ring structure

    NASA Astrophysics Data System (ADS)

    Krueger, Harald; Hamilton, Douglas P.; Moissl, Richard; Gruen, Eberhard

    particle ring material interior to Thebe's orbit. The existence of this partially evacuated gap in ring is also indirectly confirmed by Galileo in-situ energetic particle measurements (Norbert Krupp, priv. comm.). Recent modelling (Hamilton & Kr¨ger, u Nature, submitted) shows that time variable electromagnetic effects can account for all of these surprising results. In particular, when the ring particles travel through Jupiter's shadow, dust grain electric charges vary systematically, driving grains out into the Thebe Extension and matching the Galileo in-situ dust measurements.

  10. Hubble Space Telescope Servicing begins.

    NASA Astrophysics Data System (ADS)

    1993-12-01

    The day's work began when astronauts Story Musgrave and Jeff Hoffman stepped out into the cargo bay at 9h41 pm CST, Saturday (4h41 am CET, Sunday). They immediately set to work replacing two gyroscope assemblies, known as the Rate Sensor Units, two associated electronics boxes, called Electronic Control Units, and eight electrical fuse plugs. The work was completed ahead of schedule, but the astronauts had trouble closing the doors of the compartment housing the gyros and took over an hour to get them shut. The astronauts also prepared equipment for the replacement of the solar arrays. "The feeling down here is one of great satisfaction for a tremendous job today" said spacecraft communicator Greg Harbaugh in mission control. "We are very proud of the work that you all did and we are very confident in the continued success of the mission. Everything is going great and tomorrow is going to be another great day". ESA astronaut Claude Nicollier played a vital role during the spacewalk moving the astronauts and their equipment around the cargo bay with the shuttle's robot arm. The Hubble Space Telescope servicing mission features more robot arm operations than any other shuttle flight. The telescope's left-hand solar array was rolled up successfully at 6h24 am CST (1h24 pm CET). The 11-tonne observatory was rotated 180 degrees on its turntable before commands were sent to retract the second array at 8h23 am CST (3h23 pm CET). The crew stopped the retraction when it appeared the system may have jammed. Mission control instructed the crew to jettison the array, a procedure that they have trained for. Tomorrow astronauts Kathy Thornton and Tom Akers will make a six-hour spacewalk to jettison the troublesome wing, store the other in the cargo bay, and install two new panels supplied by ESA. The second set of arrays feature thermal shields and a modified thermal compensation system to prevent the flexing that affected the first pair. The Hubble Space Telescope was plucked

  11. Hubble refurbished and ready for release

    NASA Astrophysics Data System (ADS)

    1993-12-01

    ) tomorrow morning. The telescope's aperture door will open just prior to the release. ESA astronaut Claude Nicollier will operate the shuttle's robot arm during the deployment, as he has throughout the lengthy spacewalks and the retrieval of the telescope. This mission has seen more arm operations than any other. Milt Heflin, NASA's lead flight director for the mission, paid tribute to Nicollier at a news conference today. "Claude was magnificent arm driver" he said. "The arm was surgically put in place every time. Folks can be very proud of him". Endeavour is scheduled to return to Earth Monday 13 December.

  12. The surprising magnetic topology of τ Sco: fossil remnant or dynamo output?

    NASA Astrophysics Data System (ADS)

    Donati, J.-F.; Howarth, I. D.; Jardine, M. M.; Petit, P.; Catala, C.; Landstreet, J. D.; Bouret, J.-C.; Alecian, E.; Barnes, J. R.; Forveille, T.; Paletou, F.; Manset, N.

    2006-08-01

    conclude that its magnetic field is most probably a fossil remnant from the star formation stage. Based on observations obtained at the Canada-France-Hawaii Telescope (CFHT) which is operated by the National Research Council of Canada, the Institut National des Science de l'Univers of the Centre National de la Recherche Scientifique of France, and the University of Hawaii. E-mail: donati@ast.obs-mip.fr (J-FD); idh@star.ucl.ac.uk (IDH); mmj@st-andrews.ac.uk (MMJ); petit@ast.obs-mip.fr (PP); claude.catala@obspm.fr (CC); jlandstr@uwo.ca (JDL); jean-claude.bouret@oamp.fr (J-CB); evelyne.alecian@obspm.fr (EA); jrb3@st-andrews.ac.uk (JRB); forveill@cfht.hawaii.edu (TF); fpaletou@ast.obs-mip.fr (FP); manset@cfht.hawaii.edu (NM)

  13. Stephen Hales: the contributions of an Enlightenment physiologist to the study of the kidney in health and disease.

    PubMed

    Eknoyan, Garabed

    2016-02-01

    Stephen Hales (1677-1761) was an English clergyman who made major contributions to a wide range of scientific topics such as botany, chemistry, pneumatics, and physiology. Early in his career he developed a keen interest in medicine through his association with his younger physician friend at Cambridge, William Stukeley (1687-1765), with whom he dissected animals and attended experiments in the laboratory of Isaac Newton. His fame as a scientist grew and by the end of his life he had achieved an international reputation as a major scientist of the Enlightenment. He is best known for his 1733 Statical Essays, in the second part of which he describes his studies in animal physiology. Most famous amongst those are his assessments of the force of the blood, which he measured in horses and dogs. Less well known and often unrecognized are his studies on the kidney in health and disease, which are the focus of this review. Amongst others Hales described the effects of hemorrhagic shock which he observed as he bled his animals while measuring their blood pressure; he then studied the effect of increasing saline perfusion pressures on the renal secretion of urine; and delved into biochemistry in exploring the composition of and solutions to dissolve bladder stones. His 1733 statement in the introduction to his hemodynamic studies that the healthy State of the Animal principally consists, in the maintaining of a due Equilibrium between the body solids and fluids literally predicts the milieu intrieur that would ultimately be formulated in 1854 by Claude Bernard (1813-1878).

  14. STS-103 crew are interviewed by media at Pad 39B

    NASA Technical Reports Server (NTRS)

    1999-01-01

    At Launch Pad 39B, Lisa Malone, chief, Media Services at KSC introduces the STS-103 crew standing ready to answer questions from the media. From left are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, and Mission Specialists Steven L. Smith, Jean-Frangois Clervoy of France, who is with the European Space Agency (ESA), John M. Grunsfeld (Ph.D.), C. Michael Foale (Ph.D.), and Claude Nicollier of Switzerland, who is also with ESA. As a preparation for launch, the crew have been participating in Terminal Countdown Demonstration Test (TCDT) activities at KSC. The TCDT provides the crew with emergency egress training, opportunities to inspect their mission payloads in the orbiter's payload bay, and simulated countdown exercises. STS-103 is a 'call-up' mission due to the need to replace and repair portions of the Hubble Space Telescope, including the gyroscopes that allow the telescope to point at stars, galaxies and planets. The STS-103 crew will be replacing a Fine Guidance Sensor, an older computer with a new enhanced model, an older data tape recorder with a solid-state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The mission is targeted for launch Dec. 6 at 2:37 a.m. EST.

  15. An evolution in student-centered teaching.

    PubMed

    Goodman, Barbara E

    2016-09-01

    The American Physiological Society (APS) Teaching Section annually honors an educator through its Claude Bernard Distinguished Lecture at the Experimental Biology meeting. Since I knew about my selection for almost a year, I had a long time to think about what I wanted to say and how I wanted to say it. The theme of my presentation was "nothing in education makes sense except in the light of student learning." My presentation began with a video of my "And, But, Therefore" description of my educational scholarship (see Randy Olson Great Challenges Day at TEDMED 2013, Ref. 10). "Physiology is the basic foundation of all the health professions AND physiology can be hard for students to figure out BUT many physiology courses expect students to memorize a large number of facts; THEREFORE, my scholarship is to help students learn physiology better for the long-term with various types of student-centered learning opportunities." To stress the goal of student-centered learning, my brief video was followed by a 2-min video of one of my students describing her experiences with student-centered learning in one of my two-semester Advanced Human Physiology classes. Since I have been convinced that Randy Olson is an expert on science communication (11), the rest of my presentation was the story about how I have evolved from a sage-on-the-stage lecturer into a student-centered learning facilitator. I have chosen Olson's "And, But, Therefore" approach to narrative for this written version of key aspects of the presentation.

  16. Laboratory investigations of the response of Brewer-Mast ozonesondes to tropospheric ozone

    NASA Astrophysics Data System (ADS)

    Tarasick, David W.; Davies, Jonathan; Anlauf, Kurt; Watt, Maurice; Steinbrecht, Wolfgang; Claude, Hans J.

    2002-08-01

    The Brewer-Mast ozonesonde was used at Canadian stations from 1966 until 1980, when the Canadian network switched to the electrochemical concentration cell sonde. While the sondes appear to agree relatively well in the stratosphere, there is an evident discrepancy of 10-20% in tropospheric measurements [e.g., Tarasick et al., 1995, Figure 4]. Comparison of Brewer-Mast sondes with a calibrated ozone source yields some interesting insight into this discrepancy. Sonde response is strongly dependent on the preflight preparation procedures employed. Although sondes prepared via procedures introduced in the 1980s [Claude et al., 1987] perform quite well, when prepared according to the procedures used in Canada in the 1970s, Brewer-Mast sondes indicate 10-30% lower ozone than the calibrator. The following points are noted in particular: (1) a new Brewer-Mast sonde shows a large (~15%) increase in sensitivity between successive experiments; (2) especially at low (<100 ppb) O3 levels, the response even of previously flown sondes increases slowly with time; and (3) sondes show an additional slow increase of response with time that is apparently caused by ozone reactions with the phosphate buffer. The overall response curve indicated by 1, 2, and 3 implies that after correction to the observed total ozone, the earlier part of a flight would yield values that are too low, while the latter part would be too high. By applying a varying ozone input, simulating the typical variation in absolute ozone concentration experienced by a sonde in flight, we show that this can explain both the average correction factor (1.255) for the Canadian Brewer-Mast record and the 10-20% discrepancy in tropospheric measurements.

  17. RU-486: a continuing saga.

    PubMed

    1988-12-01

    A month after the approved marketing of RU-486 in France as a nonsurgical option for abortion, the company Roussel-Ulcaf withdrew the product in response to boycott threats and threats to company officials and their families. The government of France approved the drug on an experimental basis under the name of Mifepristone; the conditions of the approval were that the drug had to be used within the 1st 49 days after the 1st day of last menstruation and had to be administered under medical supervision at a hospital with the expertise to perform an abortion. Following trials in France, China, and the United Kingdom, RU-486, when administered in a single dose of 3 pills, was observed to have a 95% success and to be very safe. The international boycott and personal threats propelled a convention of more than 1,000 physicians in the World Congress of Gynecology and Obstetrics in Rio de Janeiro to sign a petition that advocated to Roussel-Uclaf the importance of insuring "that women have access to the benefits of scientific progress." The World Health Organization regretted the withdrawal of the drug as 1 off-shoot of the decision would be that developing companies would not be able to run clinical trials on RU-486. Shortly after the company's decision to remove the drug, the French Minister of Health, Claude Evin, ordered a continuation of experimental trials of RU-486. While no US companies have demonstrated interest in the drug, boycotts and threats exacerbate product liability coverage problems. However, should it prove effective in treating breast cancer, endometriosis or ectopic pregnancy, RU-486 may begin to increase in distribution and use.

  18. [Quality control of capillary blood measurements in clinical services: follow up by the biologist].

    PubMed

    Desjobert, H; Durand, G; Chérubin, N; Le Moël, G

    2001-04-01

    In Bichat-Claude Bernard Hospital, the study of capillary glucose analyzers in the aim of uniformizing the selection of glucose meters, has shown the relevance of a standardized handling in order to obtain clinically interpretable results. It has been necessary to implement a quality follow up by the biologist. In the first stage, the biochemistry laboratory, with the clinical service supervisor and the supplier, has assured the training of the medical staff habilitated to use the meters and to carry out a quality control. In the second stage, the biologist implemented a monthly control on a total blood control sample, the stability of which has been checked after the necessary addition of glucose. Dosing of that sample, which is used as an external control, is carried out in parallel by the QID Precision glucose analyzer (Abbott) and by the portable Hemocue B Glucose (Vermed), which is selected as a comparison standard. This allows a monthly control of the accuracy of the meter. The condition of the equipment, as well as the weekly control follow up, validated by the nurse, is registered on a sheet prepared by the biologist. In partnership with Vermed, we have developed a processing software of the data stored in the Hemocue, allowing the automatic issue of a report summarizing the equipment condition and the data of weekly and monthly controls follow up. This report, signed by the biologist, is sent to every Service Manager and Supervising Nurse. On the basis of our one year experience, this practice has generated an efficient collaboration between the clinical services and the biochemistry laboratory, allowing to keep the quality of the capillary glucose measurements performed in inpatients.

  19. STS-103 crew pose in front of Pad 39B

    NASA Technical Reports Server (NTRS)

    1999-01-01

    During Terminal Countdown Demonstration Test (TDCT) activities at Launch Pad 39B, the STS-103 crew pose in front of the flame trench, which is situated underneath the Mobile Launcher Platform holding Space Shuttle Discovery. Standing left to right are Mission Specialists Claude Nicollier of Switzerland, who is with the European Space Agency (ESA), C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Pilot Scott J. Kelly, Commander Curtis L. Brown Jr., and Mission Specialists Jean-Frangois Clervoy of France, also with ESA, and Steven L. Smith. One of the solid rocket boosters and the external tank that are attached to Discovery can be seen in the photo. The flame trench is made of concrete and refractory brick, and contains an orbiter flame deflector on one side and solid rocket booster flame deflector on the other. The deflectors protect the flame trench floor and pad surface from the intense heat of launch. The TCDT provides the crew with emergency egress training, opportunities to inspect their mission payloads in the orbiter's payload bay, and simulated countdown exercises. STS-103 is a 'call-up' mission due to the need to replace and repair portions of the Hubble Space Telescope, including the gyroscopes that allow the telescope to point at stars, galaxies and planets. The STS-103 crew will be replacing a Fine Guidance Sensor, an older computer with a new enhanced model, an older data tape recorder with a solid-state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The mission is targeted for launch Dec. 6 at 2:37 a.m. EST.

  20. Forging the link between nuclear reactions and nuclear structure

    NASA Astrophysics Data System (ADS)

    Dickhoff, W. H.

    2016-06-01

    A review of the recent applications of the dispersive optical model (DOM) is presented. Emphasis is on the nonlocal implementation of the DOM that is capable of describing ground-state properties accurately when data like the nuclear charge density are available. The present understanding of the role of short- and long-range physics in determining proton properties near the Fermi energy for stable closed-shell nuclei has relied mostly on data from the (e, e' p) reaction. Hadronic tools to extract such spectroscopic information have been hampered by the lack of a consistent reaction description that provides unambiguous and undisputed results. The DOM, conceived by Claude Mahaux, provides a unified description of both elastic nucleon scattering and structure information related to single-particle properties below the Fermi energy. We have recently introduced a nonlocal dispersive optical potential for both the real and imaginary part. Nonlocal absorptive potentials yield equivalent elastic differential cross sections for 40Ca as compared to local ones but change the l-dependent absorption profile suggesting important consequences for the analysis of nuclear reactions. Below the Fermi energy, nonlocality is essential for an accurate representation of particle number and the nuclear charge density. Spectral properties implied by (e, e' p) and (p, 2p) reactions are correctly described, including the energy distribution of about 10% high-momentum protons obtained at Jefferson Lab. The nonlocal DOM allows a complete description of experimental data both above (up to 200 MeV) and below the Fermi energy in 40Ca. It is further demonstrated that elastic nucleon-nucleus scattering data constrain the spectral strength in the continuum of orbits that are nominally bound in the independent-particle model. Extension of this analysis to 48Ca allows a prediction of the neutron skin of this nucleus that is larger than most predictions made so far.

  1. [Alternatives to animal experimentation v.s. animal rights terrorism].

    PubMed

    Kurosawa, Tsutomu Miki

    2008-05-01

    Systematic modern animal experimentation was established by Bernard Claude who wrote "An Introduction to the Study of Experimental Medicine" in 1865. At this point, the public was already asking that the pain and distress of experimental animals be reduced. For this, scientists, William Russell and Rex Burch in 1959 proposed the principles of alternatives to animal experimentation, the "3Rs". Since that time, animal welfare advocates have promoted the 3Rs concept in biomedical research communities. However, cruel animal experiments have continued and there are reports of radical extremists showing their opposition by invasion, arson, theft and even bombing of institutions involved, resulting in killing of the animals. SHAC, one extremist group believed to be animal welfare activitists was recognized as a terrorist group after the 9.11 tragedy in USA and the government viewed their activities very seriously. In 2001, British animal extremists invaded Japanese universities and stole laboratory resources; one individual was arrested and sentenced to prison for three years; Japanese who assisted in the incident were arrested and one was sentenced for one year. In 2006, SHAC USA members were prosecuted and sentenced for up to 6 years for their terrorism activities including arson. We need to consider the background of these activities which are financially supported by animal welfare advocates. The way we, as scientists who conduct such experiments can respond is by promoting alternatives to this experimentation. In Japan, the animal welfare law was revised in 2005 stressing the importance of 3Rs in scientific activities with animals. The promotion of 3Rs should be strengthened in the pharmaceutical community.

  2. Vitalism and the resistance to experimentation on life in the eighteenth century.

    PubMed

    Wolfe, Charles T

    2013-01-01

    There is a familiar opposition between a 'Scientific Revolution' ethos and practice of experimentation, including experimentation on life, and a 'vitalist' reaction to this outlook. The former is often allied with different forms of mechanism - if all of Nature obeys mechanical laws, including living bodies, 'iatromechanism' should encounter no obstructions in investigating the particularities of animal-machines - or with more chimiatric theories of life and matter, as in the 'Oxford Physiologists'. The latter reaction also comes in different, perhaps irreducibly heterogeneous forms, ranging from metaphysical and ethical objections to the destruction of life, as in Margaret Cavendish, to more epistemological objections against the usage of instruments, the 'anatomical' outlook and experimentation, e.g. in Locke and Sydenham. But I will mainly focus on a third anti-interventionist argument, which I call 'vitalist' since it is often articulated in the writings of the so-called Montpellier Vitalists, including their medical articles for the Encyclopédie. The vitalist argument against experimentation on life is subtly different from the metaphysical, ethical and epistemological arguments, although at times it may borrow from any of them. It expresses a Hippocratic sensibility - understood as an artifact of early modernity, not as some atemporal trait of medical thought - in which Life resists the experimenter, or conversely, for the experimenter to grasp something about Life, it will have to be without torturing or radically intervening in it. I suggest that this view does not have to imply that Nature is something mysterious or sacred; nor does the vitalist have to attack experimentation on life in the name of some 'vital force' - which makes it less surprising to find a vivisectionist like Claude Bernard sounding so close to the vitalists.

  3. STS-103 crew take part in CEIT in OPF 1

    NASA Technical Reports Server (NTRS)

    1999-01-01

    In the Orbiter Processing Facility (OPF) bay 1, STS-103 crew members check out equipment to be used on planned Extravehicular Activities (EVAs) on the mission for repair of the Hubble Space Telescope. They are taking part in a Crew Equipment Interface Test (CEIT) at KSC. From left are Mission Specialists C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland, and Steven L. Smith. Other crew members at KSC for the CEIT are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, and Jean-Frangois Clervoy of France. Nicollier and Clervoy are with the European Space Agency. Mission STS-103 is a 'call-up' due to the need to replace portions of the pointing system, the gyros, which have begun to fail on the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. The gyroscopes allow the telescope to point at stars, galaxies and planets. The STS-103 crew will not only replace gyroscopes, it will also replace a Fine Guidance Sensor and an older computer with a new enhanced model, an older data tape recorder with a solid-state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. The scheduled launch date in October is under review.

  4. Galileo and Music: A Family Affair

    NASA Astrophysics Data System (ADS)

    Fabris, D.

    2011-06-01

    According to Viviani, Galileo's first biographer, the scientist was an excellent keyboard and lute player. In turn Vincenzo Galilei, father of the illustrious scientist, had been one of the most influential music theorist of his age and also a great composer and virtuoso of the lute. Galileo and his brother Michelangelo, born in 1575, inherited Vincenzo's duel skills, both in theory and practical music: Galileo's correspondences show indeed his competence in the music and in the lute playing; Michelagnolo, after being educated in part in Galileo's house in Padua, transferred to Germany in Munich, where he became a court lute player. Nevertheless, Galileo helped for the rest of his life not only his brother but also his nephews, as documented in dozen of family letters quite important to establish the central role of the music in Galileo's everyday life, a fact almost ignored by most modern biographers. The importance of music in Galileo's output and life has been first outlined by the historian of sciences Stillman Drake and by the musicologist Claude Palisca. After their studies starting in the 1960s there is a great belief that Vincenzo influenced his son Galileo, directing him towards experimentation. The aim of this paper, following the reconstruction of Galileo's soundscape proposed by Pierluigi Petrobelli, is to reexamine the surviving historical accounts on the musical passion and talent of Galileo and his family in the several houses where they performed music (in Florence, Padua, Munich, etc.) in particular on the lute, the instrument that was an important experimental tool for the scientist.

  5. [By way of a synthesis of its conceptual evolution towards scientific medicine].

    PubMed

    de Micheli-Serra, A

    1999-01-01

    A historic outline of the evolution of medical thought toward scientific medicine is presented. Galen from Pergamon, one of science's first philosophers, wrote an Institutio logica, which can be considered as an introduction to the scientific method. Later, the Nominalists of the XIV century, precursors of modern science, thought that science's object was not the general, vague and indeterminate, but the particular, which is real and can be known directly. About the middle of the XVII Century the bases of the modern science became established thanks to a revolution formented essentially by Galileo, Bacon and Descartes. During the XVIII Century, parallel to the development of the great current of English Empiricism, a movement of scientific renewal also arose in continental Europe following the discipline of the Dutch Physicians and of Boerhaave. In the last century, Claude Bernard dominated scientific medicine, but his rigorous determinism impeded him from taking into account the immense and unforeseeable field of the random. Nowadays, we approach natural science and medicine from particular groups of facts, that is, from the responses of Nature to specific questions, but not from general laws. Furthermore, in recent epistemology, the concept that experimental data are not pure facts, but rather, facts interpreted within a hermeneutical context has been established. Finally, a general tendency to retrieve philosophical questions concerning the understanding of essence and existence can frequently be seen in scientific inquiry. In the light of the evolution of medical thought, it is possible to establish the position of scientific medicine within the movement of ideas dominating in our time.

  6. The final stages of spliceosome maturation require Spp2p that can interact with the DEAH box protein Prp2p and promote step 1 of splicing.

    PubMed Central

    Roy, J; Kim, K; Maddock, J R; Anthony, J G; Woolford, J L

    1995-01-01

    Pre-mRNA processing occurs by assembly of splicing factors on the substrate to form the spliceosome followed by two consecutive RNA cleavage-ligation reactions. The Prp2 protein hydrolyzes ATP and is required for the first reaction (Yean SL, Lin RJ, 1991, Mol Cell Biol 11:5571-5577; Kim SH, Smith J, Claude A, Lin RJ, 1992, EMBO J 11:2319-2326). The Saccharomyces cerevisiae SPP2 gene was previously identified as a high-copy suppressor of temperature-sensitive prp2 mutants (Last RL, Maddock JR, Woolford JL Jr, 1987, Genetics 117:619-631). We have characterized the function of Spp2p in vivo and in vitro. Spp2p is an essential protein required for the first RNA cleavage reaction in vivo. Depletion of Spp2p from yeast cells results in accumulation of unspliced pre-mRNAs. A temperature-sensitive spp2-1 mutant accumulates pre-mRNAs in vivo and is unable to undergo the first splicing reaction in vitro. However, spliceosomal complexes are assembled in extracts prepared from the mutant. We show that Spp2p function is required after spliceosome assembly but prior to the first reaction. Spp2p associates with the spliceosome before the first RNA cleavage reaction and is likely to be released from the spliceosome following ATP hydrolysis by Prp2p. The Prp2 and Spp2 proteins are capable of physically interacting with each other. These results suggest that Spp2p interacts with Prp2p in the spliceosome prior to the first cleavage-ligation reaction. Spp2p is the first protein that has been found to interact with a DEAD/H box splicing factor. Images FIGURE 1 FIGURE 2 FIGURE 3 FIGURE 4 FIGURE 5 FIGURE 6 FIGURE 7 FIGURE 8 FIGURE 9 PMID:7493316

  7. Ocean thermal energy conversion: Perspective and status

    SciTech Connect

    Thomas, A.; Hillis, D.L.

    1990-01-01

    The use of the thermal gradient between the warm surface waters and the deep cold waters of tropical oceans was first proposed by J. A. d'Arsonval in 1881 and tried unsuccessfully be George Claude in 1930. Interest in Ocean Thermal Energy Conversion (OTEC) and other renewable energy sources revived in the 1970s as a result of oil embargoes. At that time, the emphasis was on large floating plants miles from shore producing 250--400 MW for maintained grids. When the problems of such plants became better understood and the price of oil reversed its upward trend, the emphasis shifted to smaller (10 MW) shore-based plants on tropical islands. Such plants would be especially attractive if they produce fresh water as a by-product. During the past 15 years, major progress has been made in converting OTEC unknowns into knowns. Mini-OTEC proved the closed-cycle concept. Cost-effective heat-exchanger concepts were identified. An effective biofouling control technique was discovered. Aluminum was determined to be promising for OTEC heat exchangers. Heat-transfer augmentation techniques were identified, which promised a reduction on heat-exchanger size and cost. Fresh water was produced by an OTEC open-cycle flash evaporator, using the heat energy in the seawater itself. The current R D emphasis is on the design and construction of a test facility to demonstrate the technical feasibility of the open-cycle process. The 10 MW shore-based, closed-cycle plant can be built with today's technology; with the incorporation of a flash evaporator, it will produce fresh water as well as electrical power -- both valuable commodities on many tropical islands. The open-cycle process has unknowns that require solution before the technical feasibility can be demonstrated. The economic viability of either cycle depends on reducing the capital costs of OTEC plants and on future trends in the costs of conventional energy sources. 7 refs.

  8. Ocean thermal energy conversion: Perspective and status

    NASA Astrophysics Data System (ADS)

    Thomas, Anthony; Hillis, David L.

    The use of the thermal gradient between the warm surface waters and the deep cold waters of tropical oceans was first proposed by J. A. d'Arsonval in 1881 and tried unsuccessfully by George Claude in 1930. Interest in Ocean Thermal Energy Conversion (OTEC) and other renewable energy sources revived in the 1970s as a result of oil embargoes. At that time, the emphasis was on large floating plants miles from shore producing 250 to 400 MW for maintained grids. When the problems of such plants became better understood and the price of oil reversed its upward trend, the emphasis shifted to smaller (10 MW) shore based plants on tropical islands. Such plants would be especially attractive if they produce fresh water as a by-product. During the past 15 years, major progress has been made in converting OTEC unknowns into knowns. Mini-OTEC proved the closed cycle concept. Cost effective heat exchanger concepts were identified. An effective biofouling control technique was discovered. Aluminum was determined to be promising for OTEC heat exchangers. Heat transfer augmentation techniques were identified, which promised a reduction on heat exchanger size and cost. Fresh water was produced by an OTEC open cycle flash evaporator, using the heat energy in the seawater itself. The current R and D emphasis is on the design and construction of a test facility to demonstrate the technical feasibility of the open cycle process. The 10 MW shore-based, closed cycle plant can be built with today's technology; with the incorporation of a flash evaporator, it will produce fresh water as well as electrical power; both valuable commodities on many tropical islands. The open cycle process has unknowns that require solution before the technical feasibility can be demonstrated. The economic viability of either cycle depends on reducing the capital costs of OTEC plants and on future trends in the costs of conventional energy sources.

  9. STS-103 crew practice emergency egress in the slidewire basket

    NASA Technical Reports Server (NTRS)

    1999-01-01

    In the slidewire basket on Launch Pad 39B, STS-103 Mission Specialist Steven L. Smith reaches for the lever that will release the basket. With Smith is fellow crew member Mission Specialist Jean-Frangois Clervoy of France. The baskets are part of the emergency egress system for persons in the Shuttle vehicle or on the Rotating Service Structure. Seven slidewires extend from the orbiter access arm, with a netted, flatbottom basket suspended from each wire. The STS-103 crew are taking part in Terminal Countdown Demonstration Test (TCDT) activities in preparation for launch. The other crew members are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, and Mission Specialists C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), and Claude Nicollier of Switzerland. Clervoy and Nicollier are with the European Space Agency. The TCDT provides the crew with the emergency egress training, opportunities to inspect their mission payloads in the orbiter's payload bay, and simulated countdown exercises. STS-103 is a 'call-up' mission due to the need to replace and repair portions of the Hubble Space Telescope, including the gyroscopes that allow the telescope to point at stars, galaxies and planets. The STS-103 crew will be replacing a Fine Guidance Sensor, an older computer with a new enhanced model, an older data tape recorder with a solid-state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The mission is targeted for launch Dec. 6 at 2:37 a.m. EST.

  10. STS-103 crew practice emergency egress in the slidewire basket

    NASA Technical Reports Server (NTRS)

    1999-01-01

    In the slidewire basket on Launch Pad 39B, STS-103 Mission Specialist C. Michael Foale (Ph.D.) gets ready to pull the lever, which will release the basket. With Foale are fellow crew members Mission Specialists Claude Nicollier of Switzerland and John M. Grunsfeld (Ph.D.). The baskets are part of the emergency egress system for persons in the Shuttle vehicle or on the Rotating Service Structure. Seven slidewires extend from the orbiter access arm, with a netted, flatbottom basket suspended from each wire. The STS-103 crew are taking part in Terminal Countdown Demonstration Test (TCDT) activities in preparation for launch. The other crew members taking part are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, and Mission Specialists Steven L. Smith, and Jean-Frangois Clervoy of France. Clervoy and Nicollier are with the European Space Agency. The TCDT provides the crew with the emergency egress training, opportunities to inspect their mission payloads in the orbiter's payload bay, and simulated countdown exercises. STS-103 is a 'call-up' mission due to the need to replace and repair portions of the Hubble Space Telescope, including the gyroscopes that allow the telescope to point at stars, galaxies and planets. The STS-103 crew will be replacing a Fine Guidance Sensor, an older computer with a new enhanced model, an older data tape recorder with a solid-state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The mission is targeted for launch Dec. 6 at 2:37 a.m. EST.

  11. French roots of French neo-lamarckisms, 1879-1985.

    PubMed

    Loison, Laurent

    2011-01-01

    This essay attempts to describe the neo-Lamarckian atmosphere that was dominant in French biology for more than a century. Firstly, we demonstrate that there were not one but at least two French neo-Lamarckian traditions. This implies, therefore, that it is possible to propose a clear definition of a (neo)Lamarckian conception, and by using it, to distinguish these two traditions. We will see that these two conceptions were not dominant at the same time. The first French neo-Lamarckism (1879-1931) was structured by a very mechanic view of natural processes. The main representatives of this first period were scientists such as Alfred Giard (1846-1908), Gaston Bonnier (1853-1922) and Félix Le Dantec (1869-1917). The second Lamarckism - much more vitalist in its inspiration - started to develop under the supervision of people such as Albert Vandel (1894-1980) and Pierre-Paul Grassé (1895-1985). Secondly, this essay suggests that the philosophical inclinations of these neo-Lamarckisms reactivated a very ancient and strong dichotomy of French thought. One part of this dichotomy is a material, physicalist tradition, which started with René Descartes but developed extensively during the 18th and 19th centuries. The other is a spiritual and vitalist reaction to the first one, which also had a very long history, though it is most closely associated with the work of Henri Bergson. Through Claude Bernard, the first neo-Lamarckians tried to construct a mechanical and determinist form of evolutionary theory which was, in effect, a Cartesian theory. The second wave of neo-Lamarckians wanted to reconsider the autonomy and reactivity of life forms, in contrast to purely physical systems.

  12. Dystrophin complex functions as a scaffold for signalling proteins.

    PubMed

    Constantin, Bruno

    2014-02-01

    of a Special Issue entitled: Reciprocal influences between cell cytoskeleton and membrane channels, receptors and transporters. Guest Editor: Jean Claude Hervé.

  13. [The Vitruvian Man: an anatomical drawing for proportions by Leonardo Da Vinci].

    PubMed

    Le Floch-Prigent, P

    2008-12-01

    The aim of the study was to find out and to analyse the text by Vitruvius which inspired the famous drawing by Leonardo da Vinci (circa 1490) kept in the Galleria dell'Accademia, in Venezia, Italy: the man inscribed in one circle and in one square. The book "de Architectura" by Vitruvius Marcus Pollio was printed several times since the Renaissance when both the roman architecture of antiquity and this text became very popular. From a French translation by Claude Perrault in 1864, it became easy to find a French translation with the original text in Latin (Paris, 2003, Les Belles Lettres, French text by Pierre Gros). The drawing by Leonardo da Vinci illustrates with great accuracy and fidelity the quotation of Vitruvius (with the exception of two of the 12 main relationships). The genius of Leonardo da Vinci was to keep only one trunk, head and neck for two pairs of limbs: scapular and pelvic; to make the circle tangent to the lower edge of the square; to adjust a few features of the quotation for the equilibrium of the whole figure; and of course to bring his incredible skill as a drawer (one of the best of his century). The drawing was made on a sheet of paper 344x245mm, in black ink which became dark brown with time; several lines complete the figure above and below; a short caption and a horizontal scale appear just under the drawing. The celebrity of the drawing, a symbol of the Renaissance, of the equilibrium of man and mankind, of the universality of the artists and intellectuals of the time (Humanism) made it iconic and it has been constantly reproduced and adapted especially for advertisement and logos, not only in the medical field.

  14. A multi-disciplinary approach to the origins of music: perspectives from anthropology, archaeology, cognition and behaviour.

    PubMed

    Morley, Iain

    2014-01-01

    Archaeological evidence for musical activities pre-dates even the earliest-known cave art and it remains the case that no human culture has yet been encountered that does not practise some recognisably musical activity. Yet the human abilities to make and appreciate music have been described as "amongst the most mysterious with which [we are] endowed" (Charles Darwin, 1872) and music itself as "the supreme mystery of the science of man" (Claude Levi-Strauss, 1970). Like language, music has been the subject of keen investigation across a great diversity of fields, from neuroscience and psychology, to ethnography, to studies of its structures in its own dedicated field, musicology; unlike the evolution of human language abilities, it is only recently that the origins of musical capacities have begun to receive dedicated attention. It is increasingly clear that human musical abilities are fundamentally related to other important human abilities, yet much remains mysterious about this ubiquitous human phenomenon, not least its prehistoric origins. It is evident that no single field of investigation can address the wide range of issues relevant to answering the question of music's origins. This review brings together evidence from a wide range of anthropological and human sciences, including palaeoanthropology, archaeology, neuroscience, primatology and developmental psychology, in an attempt to elucidate the nature of the foundations of music, how they have evolved, and how they are related to capabilities underlying other important human behaviours. It is proposed that at their most fundamental level musical behaviours (including both vocalisation and dance) are forms of deliberate metrically-organised gesture, and constitute a specialised use of systems dedicated to the expression and comprehension of social and emotional information between individuals. The abilities underlying these behaviours are selectively advantageous themselves; in addition, various mechanisms

  15. What do we do, if some of the MICE magnets can't be kept cold using the two-stage coolers?

    SciTech Connect

    Green, Michael A.

    2011-01-26

    Tests of the spectrometer solenoids have not been encouraging in terms of keeping the magnets cold using three 1.5 W (at 4.2 K) coolers. The spectrometer solenoids are being rebuilt with additional cooling capacity at 4.2 K. It is hoped that there will be sufficient 4.2 K cooling to keep the magnets cold. The spectrometer solenoids can be kept cold using liquid helium (up to a boil-off of 20 liters per day). This option does not apply for the other magnets in the MICE cooling channel, because there is not enough liquid helium storage within the magnet cold mass. It is important that the MICE collaboration ask the question, “How do we keep the MICE cooling channel magnets cold, if there isn’t sufficient cooling from the 4.2 K coolers?” This report discusses the cooling requirements at both 40 K and 4.2 K for all three types of MICE cooling channel magnets. This report discusses the steps that must be taken in the magnet fabrication to permit the magnets to be cooled using a small (20 to 40 W) external 4.2 K Claude cycle refrigerator. One must also ask the question as to whether there is enough excess capacity in the decay solenoid refrigerator to cool some of the MICE magnets. A plan for cooling the magnets using a Linde 1400 series refrigerator is presented. A plan for increasing the 4.4 K refrigeration from the existing decay solenoid refrigerator is also presented.

  16. AGC1/2, the mitochondrial aspartate-glutamate carriers.

    PubMed

    Amoedo, N D; Punzi, G; Obre, E; Lacombe, D; De Grassi, A; Pierri, C L; Rossignol, R

    2016-10-01

    In this review we discuss the structure and functions of the aspartate/glutamate carriers (AGC1-aralar and AGC2-citrin). Those proteins supply the aspartate synthesized within mitochondrial matrix to the cytosol in exchange for glutamate and a proton. A structure of an AGC carrier is not available yet but comparative 3D models were proposed. Moreover, transport assays performed by using the recombinant AGC1 and AGC2, reconstituted into liposome vesicles, allowed to explore the kinetics of those carriers and to reveal their specific transport properties. AGCs participate to a wide range of cellular functions, as the control of mitochondrial respiration, calcium signaling and antioxydant defenses. AGC1 might also play peculiar tissue-specific functions, as it was found to participate to cell-to-cell metabolic symbiosis in the retina. On the other hand, AGC1 is involved in the glutamate-mediated excitotoxicity in neurons and AGC gene or protein alterations were discovered in rare human diseases. Accordingly, a mice model of AGC1 gene knock-out presented with growth delay and generalized tremor, with myelinisation defects. More recently, AGC was proposed to play a crucial role in tumor metabolism as observed from metabolomic studies showing that the asparate exported from the mitochondrion by AGC1 is employed in the regeneration of cytosolic glutathione. Therefore, given the central role of AGCs in cell metabolism and human pathology, drug screening are now being developed to identify pharmacological modulators of those carriers. This article is part of a Special Issue entitled: Mitochondrial Channels edited by Pierre Sonveaux, Pierre Maechler and Jean-Claude Martinou.

  17. Hα kinematics of the Spitzer Infrared Nearby Galaxies Survey - II

    NASA Astrophysics Data System (ADS)

    Dicaire, I.; Carignan, C.; Amram, P.; Hernandez, O.; Chemin, L.; Daigle, O.; de Denus-Baillargeon, M.-M.; Balkowski, C.; Boselli, A.; Fathi, K.; Kennicutt, R. C.

    2008-04-01

    This is the second part of an Hα kinematics follow-up survey of the Spitzer Infrared Nearby Galaxies Survey (SINGS) sample. The aim of this paper is to shed new light on the role of baryons and their kinematics and on the dark/luminous matter relation in the star-forming regions of galaxies, in relation with studies at other wavelengths. The data for 37 galaxies are presented. The observations were made using Fabry-Perot interferometry with the photon-counting camera FaNTOmM on four different telescopes, namely the Canada-France-Hawaii 3.6-m, the ESO La Silla 3.6-m, the William Herschel 4.2-m and the Observatoire du mont Mégantic 1.6-m telescopes. The velocity fields are computed using custom IDL routines designed for an optimal use of the data. The kinematical parameters and rotation curves are derived using the GIPSY software. It is shown that non-circular motions associated with galactic bars affect the kinematical parameters fitting and the velocity gradient of the rotation curves. This leads to incorrect determinations of the baryonic and dark matter distributions in the mass models derived from those rotation curves. Based on observations made with the ESO 3.60-m telescope at La Silla Observatories under programme ID 076.B-0859 and on observations obtained at the Canada-France-Hawaii Telescope (CFHT) which is operated by the National Research Council of Canada, the Institut National des Sciences de l'Univers of the Centre National de la Recherche Scientifique of France and the University of Hawaii. E-mail: isabelle@astro.umontreal.ca (ID);claude.carignan@umontreal.ca (CC) ‡ Visiting Astronomer, Canada-France-Hawaii Telescope, operated by the National Research Council of Canada, the Centre National de la Recherche Scientifique de France and the University of Hawaii.

  18. Flow field analysis of high-speed helium turboexpander for cryogenic refrigeration and liquefaction cycles

    NASA Astrophysics Data System (ADS)

    Sam, Ashish Alex; Ghosh, Parthasarathi

    2017-03-01

    Turboexpander constitutes one of the vital components of Claude cycle based helium refrigerators and liquefiers that are gaining increasing technological importance. These turboexpanders which are of radial inflow in configuration are generally high-speed micro turbines, due to the low molecular weight and density of helium. Any improvement in efficiency of these machines requires a detailed understanding of the flow field. Computational Fluid Dynamics analysis (CFD) has emerged as a necessary tool for the determination of the flow fields in cryogenic turboexpanders, which is often not possible through experiments. In the present work three-dimensional transient flow analysis of a cryogenic turboexpander for helium refrigeration and liquefaction cycles were performed using Ansys CFX®, to understand the flow field of a high-speed helium turboexpander, which in turn will help in taking appropriate decisions regarding modifications of established design methodology for improved efficiency of these machines. The turboexpander is designed based on Balje's nsds diagram and the inverse design blade profile generation formalism prescribed by Hasselgruber and Balje. The analyses include the study of several losses, their origins, the increase in entropy due to these losses, quantification of losses and the effects of various geometrical parameters on these losses. Through the flow field analysis it was observed that in the nozzle, flow separation at the nozzle blade suction side and trailing edge vortices resulted in loss generation, which calls for better nozzle blade profile. The turbine wheel flow field analysis revealed that the significant geometrical parameters of the turbine wheel blade like blade inlet angle, blade profile, tip clearance height and trailing edge thickness need to be optimised for improved performance of the turboexpander. The detailed flow field analysis in this paper can be used to improve the mean line design methodology for turboexpanders used

  19. Foreword

    NASA Astrophysics Data System (ADS)

    Aime, C.; Soummer, R.

    very short explanation of how the reports are ordered is given here. The Journées of 2003 started with the delocalized lectures (delocalized means here “not in Paris”!) of the Collège de France, of Antoine Labeyrie who wrote a report on Removal of coronagraphy residues with an adaptive hologram. Three invited seminars follow: Olivier Guyon (Pupil remapping techniques), Daniel Rouan (Ultra-nulling interferometers), and Kjetil Dohlen (Phase masks in astronomy). An illustration from Daniel Rouan's talk on the properties of Prouhet-Thué-Morse series was also selected for the cover figure of this edition. These papers are followed by the courses and communications given during the 4 days of the school, in a slightly different order of their presentation. The first two days were on atmospheric turbulence and adaptive optics for coronagraphy, and also coronagraphic space projects. Steve Ridgway gives a general introduction to the problem (Astronomy with high contrast imaging). This is followed by a presentation on Fourier and Statistical Optics: Shaped and Apodized apertures (Claude Aime), The effect of a coronagraph on the statistics of adaptive optics pinned speckles (Claude Aime and Rémi Soummer). A general introduction to the problem of atmospheric turbulence is made by Julien Borgnino. A presentation of the Concordia site with emphasis on its advantages for high contrast imaging is given by Eric Fossat. Several presentations relative to numerical simulations of Adaptive Optics and coronagraphy follow: Marcel Carbillet (AO for very high contrast imaging), Lyu Abe and Anthony Boccaletti share two presentations on Numerical simulations for coronagraphy. These presentations are followed by reports on experiments: Sandrine Thomas (SAM-the SOAR adaptive module), Pierre Baudoz (Cryogenic IR test of the 4QPM coronagraph), Anthony Boccaletti (Coronagraphy with JWST in the thermal IR). Pierre Bourget (Hg-Mask Coronagraph) ends this part with a coronagraph using a mercury

  20. Le Laboratoire de Mécanique Appliquée Raymond Chaléat a 40 ans !

    NASA Astrophysics Data System (ADS)

    Comité D'Organisation Du Colloque Ime 2002, Le

    2002-12-01

    Le LMARC a été créé par Raymond Chaléat dans les locaux de l'École Nationale d'Horlogerie (a présent Lycée Technique Jules Haag).L'équipe de recherche était alors constituée de 2 enseignants-chercheurs (Raymond Chaléat et Gérard Lallement) et d'un technicien (Bernard Prêtre). Les travaux de recherche se situaient naturellement dans le domaine de la chronométrie et en particulier dans la mécanique non linéaire analytique inhérente à la montre en fonctionnement. En effet, Raymond Chaléat fut l'élève, puis le collaborateur du Professeur Jules Haag, mathématicien et mécanicien, lui-même élève de Poincarré.Le LMARC a étendu ses activités avec l'arrivée de Claude Oudet, puis de Claude Oytana à la rhéologie des matériaux solides qui est devenue plus tard l'Équipe Propriétés Mécaniques des Matériaux. En parallèle, G. Lallement a créé une équipe Vibrations devenue à ce jour Dynamique des Structures. À ce jour, le Laboratoire compte plus de 110 personnes dont 40 doctorants.Il a depuis diversifié ses activités avec 3 nouvelles équipes tournées vers la Modélisation et la Mise en Forme des Matériaux, les Micromachines et la Biomécanique et les Mécanismes. Il a su également prendre toute sa place au sein de l'Institut des Microtechniques de Franche-Comté en contribuant à plusieurs thèmes.Notre Laboratoire a été l'un des premiers laboratoires associé au CNRS (4ème) et a toujours été rattaché à l'Université de Franche-Comté (Présidence par C. Oytana de 1996 a 2001) par l'entremise de I'UFR Sciences et Techniques. Il a toujours maintenu des liens forts avec I'ENSMM (École Nationale Supérieure de Mécanique et des Microtechniques) d'une part par ses enseignants-chercheurs et d'autre part deux de ses directeurs, Raymond Chaléat et actuellement Jean-Claude Gelin.En plus de ses relations constantes avec l'industrie régionale, le LMARC a développé des actions contractuelles avec de grands groupes tels que EDF

  1. A Glimpse of the Young Milky Way

    NASA Astrophysics Data System (ADS)

    2002-10-01

    metal-deficient stars that is currently being carried out at Hamburger Sternwarte [4]. Over a period of more than 10 years, a large collection of photographic pictures of the southern sky were obtained with the ESO 1-m Schmidt Telescope, a wide-angle telescope at the La Silla observatory in Chile that has now been decommissioned. Thanks to a large glass prism in the front of the telescope, every object in the observed sky field - stars as well as galaxies - was imaged as a small spectrum, providing a first rough idea about its type and composition. The main aim of this "Hamburg/ESO survey" (with Dieter Reimers , Associate Director of the Hamburger Sternwarte, as Principal Investigator and Lutz Wisotzki , now at Astrophysikalisches Institut Potsdam, Germany, as Project Scientist) was to find quasars (particularly active centres of galaxies), a task that was accomplished most successfully, cf. e.g., ESO PR 10/97 and ESO PR 08/00 (Report F). A very welcome by-product of this survey has been a rich harvest of very metal-poor stars . This part of the project is led by Norbert Christlieb , also from the Hamburg Observatory, and now on sabbatical leave at the Research School of Astronomy and Astrophysics of the Australian National University (Canberra, Australia). Using fast computers and advanced pattern-recognition software to analyze the photographic exposures and thus to sift through millions of registered stellar spectra, about 8000 candidates for very metal-poor stars were found. These stars are now being scrutinized spectroscopically one-by-one with many medium-sized telescopes all over the world. Confirmed candidates are then observed with the largest telescopes in the world in order to obtain very detailed spectra (of high spectral resolution), which allow the astronomers to determine their chemical composition accurately. The very metal-deficient star HE 0107-5240 ESO PR Photo 25a/02 ESO PR Photo 25a/02 [Preview - JPEG: 400 x 458 pix - 86k [Normal - JPEG: 800 x 915

  2. Argonne National Laboratory summary site environmental report for calendar year 2006.

    SciTech Connect

    Golchert, N. W.; ESH /QA Oversight

    2008-03-27

    This booklet is designed to inform the public about what Argonne National Laboratory is doing to monitor its environment and to protect its employees and neighbors from any adverse environmental impacts from Argonne research. The Downers Grove South Biology II class was selected to write this booklet, which summarizes Argonne's environmental monitoring programs for 2006. Writing this booklet also satisfies the Illinois State Education Standard, which requires that students need to know and apply scientific concepts to graduate from high school. This project not only provides information to the public, it will help students become better learners. The Biology II class was assigned to condense Argonne's 300-page, highly technical Site Environmental Report into a 16-page plain-English booklet. The site assessment relates to the class because the primary focus of the Biology II class is ecology and the environment. Students developed better learning skills by working together cooperatively, writing and researching more effectively. Students used the Argonne Site Environmental Report, the Internet, text books and information from Argonne scientists to help with their research on their topics. The topics covered in this booklet are the history of Argonne, groundwater, habitat management, air quality, Argonne research, Argonne's environmental non-radiological program, radiation, and compliance. The students first had to read and discuss the Site Environmental Report and then assign topics to focus on. Dr. Norbert Golchert and Mr. David Baurac, both from Argonne, came into the class to help teach the topics more in depth. The class then prepared drafts and wrote a final copy. Ashley Vizek, a student in the Biology class stated, 'I reviewed my material and read it over and over. I then took time to plan my paper out and think about what I wanted to write about, put it into foundation questions and started to write my paper. I rewrote and revised so I think the amount of

  3. How Much Mass Makes a Black Hole? - Astronomers Challenge Current Theories

    NASA Astrophysics Data System (ADS)

    2010-08-01

    exploded and left a magnetar remnant must have had a shorter life than the surviving stars in the cluster. "Because the lifespan of a star is directly linked to its mass - the heavier a star, the shorter its life - if we can measure the mass of any one surviving star, we know for sure that the shorter-lived star that became the magnetar must have been even more massive," says co-author and team leader Simon Clark. "This is of great significance since there is no accepted theory for how such extremely magnetic objects are formed." The astronomers therefore studied the stars that belong to the eclipsing double system W13 in Westerlund 1 using the fact that, in such a system, masses can be directly determined from the motions of the stars. By comparison with these stars, they found that the star that became the magnetar must have been at least 40 times the mass of the Sun. This proves for the first time that magnetars can evolve from stars so massive we would normally expect them to form black holes. The previous assumption was that stars with initial masses between about 10 and 25 solar masses would form neutron stars and those above 25 solar masses would produce black holes. "These stars must get rid of more than nine tenths of their mass before exploding as a supernova, or they would otherwise have created a black hole instead," says co-author Ignacio Negueruela. "Such huge mass losses before the explosion present great challenges to current theories of stellar evolution." "This therefore raises the thorny question of just how massive a star has to be to collapse to form a black hole if stars over 40 times as heavy as our Sun cannot manage this feat," concludes co-author Norbert Langer. The formation mechanism preferred by the astronomers postulates that the star that became the magnetar - the progenitor - was born with a stellar companion. As both stars evolved they would begin to interact, with energy derived from their orbital motion expended in ejecting the requisite

  4. Elaboration d'un composite conducteur a base de polypyrrole et de nanofibres de cellulose

    NASA Astrophysics Data System (ADS)

    Bideau, Benoit

    Le projet de production de nanocellulose à grande échelle par l'équipe de recherche du professeur Claude Daneault, ne pourra se faire sans avoir démontré sa quelconque utilité sur le marché économique. C'est dans cette optique que s'est articulé mon travail afin de mettre en avant une des voix de valorisation de ces nanocelluloses. Nous avons travaillé plus précisément sur le développement d'un nanocomposite conducteur biodégradable. Nous nous sommes proposé dans ce travail de développer une technique simple et écologique permettant la conception d'un matériau composite conducteur. Nous avons étudié l'influence des nanofibres de cellulose, du pyrrole, de la température, de la durée de polymérisation et l'ajout d'additifs dans le matériau composite. L'étude de ces paramètres nous a permis de déterminer les meilleures conditions pour le développement d'un film composite conducteur avec des propriétés mécaniques acceptables. L'ajout de ce renfort (nanofibres), au sein de la matrice de polypyrrole a permis d'obtenir des films intéressants, de part leurs propriétés mécaniques, électriques et de leur caractère biodégradable. Des comparaisons ont été effectuées avec des fibres oxydées, afin d'étudier l'apport des nanofibres de cellulose au composite. Notre étude a ensuite été élargie à l'ajout d'additifs dans les matériaux conducteurs afin d'améliorer certaines propriétés du composite. L'objectif de ce travail visait l'étude de l'incorporation des nanofibres de cellulose dans une matrice de polypyrrole en vue de son utilisation en tant que matériau conducteur biodégradable pour des applications dans le domaine énergétique. Mots Clés: Nanocellulose, polypyrrole, composite, conducteur, biodégradable, propriétés mécaniques, additifs.

  5. Édouard Manet's Tabes Dorsalis: From Painful Ataxia to Phantom Limb.

    PubMed

    Bogousslavsky, Julien; Tatu, Laurent

    2016-01-01

    . Having become bedridden, he had to be amputated of one leg, which was developing gangrene probably associated with ergot overuse. While he died shortly thereafter, we have some witness anecdotes suggesting that he experienced a phantom limb: when Claude Monet (1840-1926) visited him and sat down on his bed, Manet violently shouted at him that he was just sitting on his (absent) leg, which provoked terrible pains. With its facts and mysteries, the subtle interaction between Manet's illness and his work output remains one of the most intriguing stories in neurology of art.

  6. Medicine in the Encyclopédie (1751-1780) of Diderot and d'Alembert.

    PubMed

    De Santo, Natale G; Bisaccia, Carmela; Cirillo, Massimo; Richet, Gabriel

    2011-01-01

    On July 1, 1751, the royal Parisian printer Le Breton published the first volume of the Encyclopédie of Diderot and d'Alembert, a rational dictionary, in folio and in alphabetical order, sold by subscription. The whole work was completed in 1780 (a total of 35 volumes, of which 12 were of illustrations, 4 of supplements and 2 of indices). In 1782 it was followed by the Encyclopédie méthodique, printed by Panckoucke, which ended in 1832 with volume number 166. The frontispiece of the first volume, designed by Charles-Nicolas Cochin Jr. and engraved by Benoît-Louis Prévost showed the columns of an Ionic temple where the Truth appears between Reason and Philosophy. Reason is shown trying to break the veil of Truth, and Philosophy trying to embellish it. Below are the philosophers, their eyes fixed on Truth. Theology is on his knees with his back facing Truth, and seems to receive light from the top. The subsequent chain of figures depicts Memory, Ancient History, Modern History, Geometry, Astronomy and Physics. Below are Optics, Botany, Chemistry and Agriculture. On the bottom line one finds the representatives of arts and professions derived from science. In a 42-page preface ("Discours préliminaire") d'Alembert discussed the path to new knowledge as one "based on what we receive through senses. Ideas depend on senses." The medical collaborators were, or became, famous. Medicine was considered to be rooted in experiment, in patients and in measurements. Functions started to be described with numbers. It was the birth of determinism which was later reinforced by Magendie and Claude Bernard. Albrecht Haller, president of the Academy of Science at Göttingen, as well as a member of all European academies, wrote seminal entries. New accurate definitions appeared for life, disease, death, infections, plague, epidemics, hygiene, fevers and edema. Semiology, the study of signs, became the visible explanation of deranged function, diagnosis and prognosis.

  7. Superior sulcus (Pancoast) tumors: current evidence on diagnosis and radical treatment

    PubMed Central

    Foroulis, Christophoros N.; Darwiche, Kaid; Katsikogiannis, Nikolaos; Machairiotis, Nikolaos; Karapantzos, Ilias; Tsakiridis, Kosmas; Huang, Haidong; Zarogoulidis, Konstantinos

    2013-01-01

    Pancoast tumors account for less than 5% of all bronchogenic carcinomas. These tumors are located in the apex of the lung and involve through tissue contiguity the apical chest wall and/or the structures of the thoracic inlet. The tumors become clinically evident with the characteristic symptoms of the “Pancoast-Tobias syndrome” which includes Claude-Bernard-Horner syndrome, severe pain in the shoulder radiating toward the axilla and/or scapula and along the ulnar distribution of the upper arm, atrophy of hand and arm muscles and obstruction of the subclavian vein resulting in edema of the upper arm. The diagnosis will be made by the combination of the characteristic clinical symptoms with the radiographic findings of a mass or opacity in the apex of the lung infiltrating the 1st and/or 2nd ribs. A tissue diagnosis of the tumor via CT-guided FNA/B should always be available before the initiation of treatment. Bronchoscopy, thoracoscopy and biopsy of palpable supraclavicular nodes are alternative ways to obtain a tissue diagnosis. Adenocarcinomas account for 2/3 of all Pancoast tumors, while the rest of the tumors are squamous cell and large cell carcinomas. Magnetic resonance imaging of the thoracic inlet is always recommended to define the exact extent of tumor invasion within the thoracic inlet before surgical intervention. Pancoast tumors are by definition T3 or T4 tumors. Induction chemo-radiotherapy is the standard of care for any potentially resectable Pancoast tumor followed by an attempt to achieve a complete tumor resection. Resection can be made through a variety of anterior and posterior approaches to the thoracic inlet. The choice of the approach depends on the location of the tumor (posterior - middle - anterior compartment of the thoracic inlet) and the depth/extent of invasion. Prognosis depends mainly on T stage of tumor, response to preoperative chemo-radiotherapy and completeness of resection. Resection of the invaded strictures of the

  8. Listening to the Shepard-Risset Glissando: the Relationship between Emotional Response, Disruption of Equilibrium, and Personality

    PubMed Central

    Vernooij, Eveline; Orcalli, Angelo; Fabbro, Franco; Crescentini, Cristiano

    2016-01-01

    The endless scale illusion, obtained by cyclically repeating a chromatic scale made up of Shepard tones, has been used in a variety of musical works. Music psychology and neuroscience has been interested in this particular psychoacoustic phenomenon mainly for studying the cognitive processes of pitch perception involved. In the present study, we investigated the emotional states induced by the Shepard-Risset glissando, a variant of the Shepard scale. For this purpose we chose three musical stimuli: a Matlab-generated Shepard Risset glissando, Jean-Claude Risset's Computer Suite from Little Boy, which presents a Shepard-Risset glissando integrated in the aesthetic context of a composition, and an ordinary orchestral glissando taken from the opening of Iannis Xenakis's Metastasis. Seventy-three volunteers completed a listening experiment during which they rated their emotional response to these stimuli on a seven-point Likert scale and indicated whether they had experienced a disruption of equilibrium. Personality was also measured with the Five-Factor Model of personality traits. The results show that negative emotions were most strongly evoked during listening to each of the stimuli. We also found that the Shepard-Risset glissando illusion, both within the aesthetic context of a musical composition and on its own, was capable of evoking disruption of equilibrium, frequently leading to the associated feeling of falling. Moreover, generally for the Shepard-Risset glissando illusion, higher negative emotional ratings were given by individuals who had experienced a feeling of disturbance of equilibrium relative to those who had not had this experience. Finally, we found a complex pattern of relationships between personality and the subjective experience of the glissando. Openness to experience correlated positively with positive emotion ratings for the Computer Suite, while agreeableness correlated negatively with positive emotion ratings for the Matlab stimulus

  9. SIMMAX: A modern analog technique to deduce Atlantic sea surface temperatures from planktonic foraminifera in deep-sea sediments

    NASA Astrophysics Data System (ADS)

    Pflaumann, Uwe; Duprat, Josette; Pujol, Claude; Labeyrie, Laurent D.

    1996-02-01

    leave the system.) (Paper 95PA01743,SIMMAX: A modern analog technique to deduce Atlantic sea surfacetemperatures from planktonic foraminifera in deep-sea sediments, UwePflaumann, Josette Duprat, Claude Pujol, and Laurent D. Labeyrie).Diskette may be ordered from American Geophysical Union, 2000Florida Avenue, N.W., Washington, DC 20009; Payment mustaccompany order.

  10. The 2016 Transit of Mercury Observed from Major Solar Telescopes and Satellites

    NASA Astrophysics Data System (ADS)

    Pasachoff, Jay M.; Schneider, Glenn; Gary, Dale; Chen, Bin; Sterling, Alphonse C.; Reardon, Kevin P.; Dantowitz, Ronald; Kopp, Greg A.

    2016-10-01

    We report observations from the ground and space of the 9 May 2016 transit of Mercury. We build on our explanation of the black-drop effect in transits of Venus based on spacecraft observations of the 1999 transit of Mercury (Schneider, Pasachoff, and Golub, Icarus 168, 249, 2004). In 2016, we used the 1.6-m New Solar Telescope at the Big Bear Solar Observatory with active optics to observe Mercury's transit at high spatial resolution. We again saw a small black-drop effect as 3rd contact neared, confirming the data that led to our earlier explanation as a confluence of the point-spread function and the extreme solar limb darkening (Pasachoff, Schneider, and Golub, in IAU Colloq. 196, 2004). We again used IBIS on the Dunn Solar Telescope of the Sacramento Peak Observatory, as A. Potter continued his observations, previously made at the 2006 transit of Mercury, at both telescopes of the sodium exosphere of Mercury (Potter, Killen, Reardon, and Bida, Icarus 226, 172, 2013). We imaged the transit with IBIS as well as with two RED Epic IMAX-quality cameras alongside it, one with a narrow passband. We show animations of our high-resolution ground-based observations along with observations from XRT on JAXA's Hinode and from NASA's Solar Dynamics Observatory. Further, we report on the limit of the transit change in the Total Solar Irradiance, continuing our interest from the transit of Venus TSI (Schneider, Pasachoff, and Willson, ApJ 641, 565, 2006; Pasachoff, Schneider, and Willson, AAS 2005), using NASA's SORCE/TIM and the Air Force's TCTE/TIM. See http://transitofvenus.info and http://nicmosis.as.arizona.edu.Acknowledgments: We were glad for the collaboration at Big Bear of Claude Plymate and his colleagues of the staff of the Big Bear Solar Observatory. We also appreciate the collaboration on the transit studies of Robert Lucas (Sydney, Australia) and Evan Zucker (San Diego, California). JMP appreciates the sabbatical hospitality of the Division of Geosciences and

  11. Endeavour blasts-off on ambitious mission

    NASA Astrophysics Data System (ADS)

    1993-12-01

    "I am delighted to see the servicing mission off to such a beautiful start", said Roger Bonnet, ESA's Director of Science, who watched the launch from the Kennedy Space Center, Florida. "We are anxious to see the Hubble Space Telescope restored to its full capability so astronomers world- wide can take advantage of this unique observatory". During the eight and a half minute climb to orbit ESA astronaut Claude Nicollier helped the shuttle commander and pilot monitor the cockpit displays. Nicollier is the first international astronaut to serve as a shuttle's flight engineer. He will perform the same task at the end of the mission for reentry and landing. The European Space Agency has a major role in the telescope servicing mission. In addition to the presence of its astronaut, the agency is supplying new, improved power generating solar arrays and helped NASA test the Costar system of corrective optics. Nicollier will be responsible for operation of the shuttle's robot arm during the 11-day mission. He will use the arm to pluck the telescope from orbit and move astronauts and equipment around the payload bay during the mission's five spacewalks. The astronauts are spending their first hours in space setting up equipment in the orbiter's crew cabin. They will fire the shuttle's manoeuvring jets before going to bed to begin the two-day pursuit of the orbiting telescope. There will be three orbital manoeuvres tomorrow to further close the gap. The shuttle is due to reach the telescope Saturday and repair work will begin Sunday. Checkouts of the four space suits and the robot arm will occupy the crew tomorrow. Nicollier will use the arm to inspect the equipment in the cargo bay and later practise the manoeuvre he will use on Saturday to capture the telescope. Hubble Space Telescope science operations will be suspended at midnight tonight EST (06h00 a.m. CET tomorrow) and the HST aperture door closed at 07h30 a.m. EST (01h30 p.m. CET).

  12. CONCEPTUAL DESIGN REPORT FOR A FAST MUON TRIGGER

    SciTech Connect

    OBRIEN,E.; BASYE, A.; ISENHOWER, D.; JUMPER, D.; SPARKS, N.; TOWELL, R.; WATTS, C.; WOOD, J.; WRIGHT, R.; HAGGERTY, J.; LYNCH, D.; BARISH, K.; EYSER, K.O.; SETO, R.; HU, S.; LI, X.; ZHOU, S.; GLENN, A.; KINNEY, E.; KIRILUK, K.; NAGLE, J.; CHI, C.Y.; SIPPACH, W.; ZAJC. W.; BUTLER, C.; HE, X.; OAKLEY, C.; YING, J.; BLACKBURN, J.; CHIU, M.; PERDEKAMP, M.G.; KIM, Y.J.; KOSTER, J.; LAYTON, D.; MAKINS, N.; MEREDITH, B.; NORTHACKER, D.; PENG, J.-C.; SEIDL, R.; THORSLAND, E.; WADHAMS, S.; WILLIAMSON, S.; YANG, R.; HILL, J.; KEMPEL, T.; LAJOIE, J.; SLEEGE, G.; VALE, C.; WEI, F.; SAITO, N.; HONG, B.; KIM, B.; LEE, K.; LEE, K.S.; PARK, S.; SIM, K.-S.; AOKI, K.; DAIRAKU, S.; IMAI, K.; KARATSU, K.; MURAKAMI, T.; SATO, A.; SENZAKA, K.; SHOJI, K.; TANIDA, K.; BROOKS, M.; LEITCH, M.; ADAMS, J.; CARINGI, A.; FADEM, B.; IDE, J.; LICHTENWALNER, P.; FIELDS, D.; MAO, Y.; HAN, R.; BUNCE, G.; XIE, W.; FUKAO, Y.; TAKETANI, A.; KURITA, K.; MURATA, J.

    2007-08-01

    This document is a Conceptual Design Report for a fast muon trigger for the PHENIX experiment that will enable the study of flavor separated quark and anti-quark spin polarizations in the proton. A powerful way of measuring these polarizations is via single spin asymmetries for W boson production in polarized proton-proton reactions. The measurement is done by tagging W{sup +} and W{sup -} via their decay into high transverse momentum leptons in the forward directions. The PHENIX experiment is capable of measuring high momentum muons at forward rapidity, but the current online trigger does not have sufficient rejection to sample the rare leptons fromW decay at the highest luminosities at the Relativistic Heavy Ion Collider (RHIC). This Report details the goals, design, R&D, and schedule for building new detectors and trigger electronics to use the full RHIC luminosity to make this critical measurement. The idea for W boson measurements in polarized proton-proton collisions at RHIC was first suggested by Jacques Soffer and Claude Bourrely in 1995. This prompted the RIKEN institute in Japan to supply funds to build a second muon arm for PHENIX (south muon arm). The existence of both a north and south muon arm makes it possible to utilize a Z{sup 0} sample to study and control systematic uncertainties which arise in the reconstruction of high momentum muons. This document has its origins in recommendations made by a NSAC Subcommittee that reviewed the U.S. Heavy Ion Physics Program in June 2004. Part of their Recommendation 1 was to 'Invest in near-term detector upgrades of the two large experiments, PHENIX and STAR'. In Recommendation 2 the subcommittee stated '- detector improvements proceed at a rate that allows a timely determination of the flavor dependence of the quark-antiquark sea polarization through W-asymmetry measurements' as we are proposing here. On September 13, 2004 DOE requested from BNL a report articulating a research plan for the RHIC spin physics

  13. Tropical volcanic islands: best first cycle erosion laboratories.

    NASA Astrophysics Data System (ADS)

    Rad, S.; Rive, K.; Gaillardet, J.; Allegre, C. J.

    2007-12-01

    with higher mechanical denudation rates. \\small Setareh Denise Rad, Claude Jean Allegre and Pascale Louvat, 2007, Hidden erosion on volcanic islands, Earth and Planetary Science Letters. In Press.

  14. The MIT Program, Competition, and Ethics

    NASA Astrophysics Data System (ADS)

    Bradt, Hale V.

    2013-01-01

    The MIT program in x-ray astronomy was, and still is, diverse and productive. Bruno Rossi and later George Clark, as the nominal leaders of the “x-ray astronomy group” created a “hands-off” culture wherein individual researchers could develop their own independent programs. Walter Lewin, Claude Canizares, and I as well as those in the next academic generations, e.g., Saul Rappaport and George Ricker, were able to thrive in this environment. MIT researchers were principal investigators or providers of x-ray instruments on sounding rockets and balloons in the 1960s and then in later years on nine satellite missions, OSO-7, SAS-3, HEAO-1, Einstein, ASCA, RXTE, Chandra, HETE-2, and Suzaku. Such a diverse program involved collaborations with other institutions and of course striving for primacy in discovery and competition for NASA resources. Looking back, I see a high degree of ethical behavior among the observational x-ray community during those years. In competition, we remembered that we might well be collaborating the following year and behaved accordingly. Many of us in the x-ray community had been friends since graduate school days and did not want to lose those relationships. Am I viewing the past through rose colored glasses? I think not. A vignette on this topic: In 1967, I was debating vigorously with Herb Gursky of AS&E about which institution, MIT or AS&E, should be the lead on the fourth paper (Oda et al. 1967, ApJ 148, L5) based on data from the 1966 AS&E rocket flight which had led to Allan Sandage’s (and Japanese) identification of Sco X-1 (Sandage, et al. 1966, ApJ. 146, 316). I and my Italian colleague, Gianfranco Spada, and our Japanese colleague, Minoru Oda, both then visiting MIT, had actively supported that flight. After one rather heated discussion with Herb about this, - I was the heated one; he always remained calm - he left my office saying: “Hale, however this comes out, let’s remain friends.” I treasured that comment and

  15. Quantifying the impact of daily and seasonal variation in sap pH on xylem dissolved inorganic carbon estimates in plum trees.

    PubMed

    Erda, F G; Bloemen, J; Steppe, K

    2014-01-01

    In studies on internal CO2 transport, average xylem sap pH (pH(x)) is one of the factors used for calculation of the concentration of dissolved inorganic carbon in the xylem sap ([CO2 *]). Lack of detailed pH(x) measurements at high temporal resolution could be a potential source of error when evaluating [CO2*] dynamics. In this experiment, we performed continuous measurements of CO2 concentration ([CO2]) and stem temperature (T(stem)), complemented with pH(x) measurements at 30-min intervals during the day at various stages of the growing season (Day of the Year (DOY): 86 (late winter), 128 (mid-spring) and 155 (early summer)) on a plum tree (Prunus domestica L. cv. Reine Claude d'Oullins). We used the recorded pH(x) to calculate [CO2*] based on T(stem) and the corresponding measured [CO2]. No statistically significant difference was found between mean [CO2*] calculated with instantaneous pH(x) and daily average pH(x). However, using an average pH(x) value from a different part of the growing season than the measurements of [CO2] and T(stem) to estimate [CO2*] led to a statistically significant error. The error varied between 3.25 ± 0.01% under-estimation and 3.97 ± 0.01% over-estimation, relative to the true [CO2*] data. Measured pH(x) did not show a significant daily variation, unlike [CO2], which increased during the day and declined at night. As the growing season progressed, daily average [CO2] (3.4%, 5.3%, 7.4%) increased and average pH(x) (5.43, 5.29, 5.20) decreased. Increase in [CO2] will increase its solubility in xylem sap according to Henry's law, and the dissociation of [CO2*] will negatively affect pH(x). Our results are the first quantifying the error in [CO2*] due to the interaction between [CO2] and pH(x) on a seasonal time scale. We found significant changes in pH(x) across the growing season, but overall the effect on the calculation of [CO2*] remained within an error range of 4%. However, it is possible that the error could be more

  16. Reconstruction of the Abdominal Wall in Anatomical Plans. Pre- and Postoperative Keys in Repairing “Cold” Incisional Hernias

    PubMed Central

    POPA, FLORINA; ROSCA, OANA; GEORGESCU, ALEXANDRU; CANNISTRA, CLAUDIO

    2016-01-01

    Background and aims The clinical results of the vertical “vest-over-pants” Mayo repair were evaluated, and the risk factors for incisional hernia recurrence were studied. The purpose of this study is to point out the importance of reducing pre and post operative risk factors in the incisional hernia repair process in order to achieve a physiologically normal abdominal wall. Methods Twenty patients diagnosed with incisional hernia underwent an abdominal reconstruction procedure using the Mayo (Paletot) technique at Bichat Claude Bernard Hospital between 2005 and 2015. All procedures were performed by a single surgeon and all patients were pre-operatively prepared, identifying all coexisting conditions and treating them accordingly before undergoing surgery. Results All patients underwent at least one surgical operation before the hernia repair procedure and a quarter had experienced at least three, prior to this one. Nine patients had a body mass index of >30 kg/m2. Additional risk factors and comorbidities included obesity in 45%, diabetes mellitus in 10%, smoking in 55%, and high blood pressure in 40%. Hernia defect width was from 3 cm (25% F) to 15 cm (5% M) of which nine patients (45%) had a 10 cm defect. Most of the patients had an average hospitalization of 7 days. The patients were carefully monitored and were called on periodic consultations after 3, 6, and 12 months from the moment of the procedure. Patient feedback regarding hernia recurrence and complaints about the scar were noted. Physical examination is essential in determining the hernia recurrence therefore the scar was examined for any abnormalities that may have occurred, which was defined as any palpable or detected fascial defect located within seven centimeters of the hernia repair. Post-operative complications: seroma formation, wound hematoma, superficial and deep wound infection, recurrences and chronic pain were followed and no complications were registered during the follow-up period

  17. FILAMENT FORMATION BY ESCHERICHIA COLI AT INCREASED HYDROSTATIC PRESSURES1

    PubMed Central

    Zobell, Claude E.; Cobet, Andre B.

    1964-01-01

    ZoBell, Claude E. (University of California, La Jolla), and Andre B. Cobet. Filament formation by Escherichia coli at increased hydrostatic pressures. J. Bacteriol. 87:710–719. 1964.—The reproduction as well as the growth of Escherichia coli is retarded by hydrostatic pressures ranging from 200 to 500 atm. Reproduction was indicated by an increase in the number of cells determined by plating on EMB Agar as well as by direct microscopic counts. Growth, which is not necessarily synonymous with reproduction, was indicated by increase in dry weight and protein content of the bacterial biomass. At increased pressures, cells of three different strains of E. coli tended to form long filaments. Whereas most normal cells of E. coli that developed at 1 atm were only about 2 μ long, the mean length of those that developed at 475 atm was 2.93 μ for strain R4, 3.99 μ for strain S, and 5.82 μ for strain B cells. Nearly 90% of the bacterial biomass produced at 475 atm by strain B was found in filaments exceeding 5 μ in length; 74.7 and 16.4% of the biomass produced at 475 atm by strains S and R4, respectively, occurred in such filaments. Strain R4 formed fewer and shorter (5 to 35 μ) filaments than did the other two strains, whose filaments ranged in length from 5 to >100 μ. The bacterial biomass produced at all pressures had approximately the same content of protein and nucleic acids. But at increased pressures appreciably more ribonucleic acid (RNA) and proportionately less deoxyribonucleic acid (DNA) was found per unit of biomass. Whereas the RNA content per cell increased with cell length, the amount of DNA was nearly the same in long filaments formed at increased pressure as in cells of normal length formed at 1 atm. The inverse relationship between the concentration of DNA and cell length in all three strains of E. coli suggests that the failure of DNA to replicate at increased pressure may be responsible for a repression of cell division and consequent filament

  18. Memories of Maurice Jacob (1933-2007) Proceedings of the Maurice Jacob Memorial Meeting (CERN, 11 September 2007) Memories of Maurice Jacob (1933-2007) Proceedings of the Maurice Jacob Memorial Meeting (CERN, 11 September 2007)

    NASA Astrophysics Data System (ADS)

    Alvarez-Gaume, Luis; Heinz, Ulrich

    2008-07-01

    Maurice Jacob passed away unexpectedly on 2 May 2007. Soon after the terrible news arrived, it was thought appropriate to organize a memorial meeting at CERN. The meeting took place on 11 September 2007, and a large number of friends and colleagues participated in the event. The idea was to have brief presentations on the many scientific activities in which Maurice had been engaged, to provide a sketch of his personal trajectory. We also had spontaneous anecdotes and recollections from the audience which, unfortunately, did not make it into this special issue but enriched all of us present. The meeting took place in an afternoon, hence we were faced with the difficult task of selecting from the many presentations that could have been made by his colleagues and collaborators. The end results are the papers contained in this special issue. They provide a short overview of the breadth and depth of Maurice's physics, on the one hand, and of his deep commitment to European and world physics and to the interface between science and society, on the other hand. The first two talks were given by his fellow students and life-long friends Claude Cohen-Tannoudji and Robert Pick. These were mostly personal recollections, less focussed on scientific issues per se but reminding us how Maurice grew into the renowned scientist he later became. Cecilia Jarlskog, a longtime collaborator and friend, provided us with a beautiful view of the wonderfully multifaceted activities Maurice was able to accomplish. Peter Landshoff also spoke about his more than 35 years of personal and scientific interaction with Maurice. The talks presented during the second part of the meeting went a bit more into the technical details of the wide spectrum of scientific activities pursued by Maurice. We had contributions by Helmut Satz (whose transparencies were kindly presented by Urs Wiedemann) and Ulrich Heinz, with the closing talk presented by John Ellis. We have lost a great friend and an excellent

  19. Radically Different Kinetics at Low Temperatures

    NASA Astrophysics Data System (ADS)

    Sims, Ian

    2014-06-01

    The use of the CRESU (Cinétique de Réaction en Ecoulement Supersonique Uniforme, or Reaction Kinetics in Uniform Supersonic Flow) technique coupled with pulsed laser photochemical kinetics methods has shown that reactions involving radicals can be very rapid at temperatures down to 10 K or below. The results have had a major impact in astrochemistry and planetology, as well as proving an exacting test for theory. The technique has also been applied to the formation of transient complexes of interest both in atmospheric chemistry and combustion. Until now, all of the chemical reactions studied in this way have taken place on attractive potential energy surfaces with no overall barrier to reaction. The F + H2 {→} HF + H reaction does possess a substantial energetic barrier ({\\cong} 800 K), and might therefore be expected to slow to a negligible rate at very low temperatures. In fact, this H-atom abstraction reaction does take place efficiently at low temperatures due entirely to tunneling. I will report direct experimental measurements of the rate of this reaction down to a temperature of 11 K, in remarkable agreement with state-of-the-art quantum reactive scattering calculations by François Lique (Université du Havre) and Millard Alexander (University of Maryland). It is thought that long chain cyanopolyyne molecules H(C2)nCN may play an important role in the formation of the orange haze layer in Titan's atmosphere. The longest carbon chain molecule observed in interstellar space, HC11N, is also a member of this series. I will present new results, obtained in collaboration with Jean-Claude Guillemin (Ecole de Chimie de Rennes) and Stephen Klippenstein (Argonne National Labs), on reactions of C2H, CN and C3N radicals (using a new LIF scheme by Hoshina and Endo which contribute to the low temperature formation of (cyano)polyynes. H. Sabbah, L. Biennier, I. R. Sims, Y. Georgievskii, S. J. Klippenstein, I. W. M. Smith, Science 317, 102 (2007). S. D. Le Picard, M

  20. ARC+(Registered Trademark) and ARC PC Welding Simulators: Teach Welders with Virtual Interactive 3D Technologies

    NASA Technical Reports Server (NTRS)

    Choquet, Claude

    2011-01-01

    123 Certification Inc., a Montreal based company, has developed an innovative hands-on welding simulator solution to help build the welding workforce in the most simple way. The solution lies in virtual reality technology, which has been fully tested since the early 90's. President and founder of 123 Certification Inc., Mr. Claude Choquet Ing. Msc. IWE. acts as a bridge between the welding and the programming world. Working in these fields for more than 20 years. he has filed 12 patents world-wide for a gesture control platform with leading edge hardware related to simulation. In the summer of 2006. Mr Choquet was proud to be invited to the annual IIW International Weld ing Congress in Quebec City to launch the ARC+ welding simulator. A 100% virtual reality system and web based training center was developed to simulate multi process. multi-materiaL multi-position and multi pass welding. The simulator is intended to train welding students and apprentices in schools or industries. The welding simulator is composed of a real welding e[eetrode holder (SMAW-GTAW) and gun (GMAW-FCAW). a head mounted display (HMD), a 6 degrees of freedom tracking system for interaction between the user's hands and head. as well as external audio speakers. Both guns and HMD are interacting online and simultaneously. The welding simulation is based on the law of physics and empirical results from detailed analysis of a series of welding tests based on industrial applications tested over the last 20 years. The simulation runs in real-time, using a local logic network to determine the quality and shape of the created weld. These results are based on the orientation distance. and speed of the welding torch and depth of penetration. The welding process and resulting weld bc.1d are displayed in a virtual environment with screenplay interactive training modules. For review. weld quality and recorded process values can be displayed and diagnosed after welding. To help in the le.tming process, a