Sample records for claude amra norbert

  1. [Was Claude Bernard an atheist?].

    PubMed

    Donnet, V

    1998-01-01

    During his stay at Villefranche-sur-Saône College, Claude Bernard became acquainted with Ferdinand Donnet, appointed a short while ago, priest of the Parish. This priest became Cardinal and carried out his apostolate at Bordeaux for 47 years. 40 years after their meeting at Villefranche, Cardinal Donnet and Claude Bernard found again each other as "Sénateurs d'Empire" in Paris. In his writings, Claude Bernard never mentioned Religion: he rather gave impression, in many ways, of being anticlerical! Paul Bert and his colleagues looked upon Claude Bernard as a great priest of atheism. Shortly after his death, Cardinal Donnet wrote a letter where he entirely proved that Claude Bernard has been, on the contrary, a fervent catholic.

  2. [Norbert Elias on the phenomenology of aging and death].

    PubMed

    Faria, Lina; Santos, Luiz Antonio de Castro; Patiño, Rafael Andrés

    2017-12-18

    This study focuses on the contribution by German sociologist Norbert Elias (1897-1990) to the theme of aging and death. A reading of Elias' work allows reconsidering his analyses and perspectives on the thresholds of aging and death in societies with different demographic histories. Norbert Elias addressed these issues in The Loneliness of the Dying, published in 1982 in Germany and with an expanded version in 1985 in England. The author delves into his own experience with aging as inspiration for constructing his work, referring to his personal history and career as a social scientist, dialoguing with both the social and human sciences and with knowledge in the field of health. Elias endeavors to understand how the aging body is experienced and represented by the elderly person and how younger people grasp the processes and stages of advancing age. His thinking is attuned to the multiplicity of metaphors and meanings on finitude, on processes of aging and rites of passage in "younger" societies or more demographically "mature" ones. These are the concerns and inquiries of Norbert Elias that we will reflect on, in dialogue with his studies on finitude or the final moments of existence.

  3. Rocks at Belle-Isle, Port-Domois, Claude Monet

    ERIC Educational Resources Information Center

    Rauch, Marion Cosgrove

    2004-01-01

    This article is a description of the artist Claude Monet. The article describes the life and art of Claude Monet, focusing in on his work, Rocks at Bell-Isle, Port-Domois. A brief discussion of the significant elements of the painting is provided. The article also includes a list of discussion questions and suggested classroom activities.

  4. Claude Ruggieri

    NASA Technical Reports Server (NTRS)

    2004-01-01

    During the 19th century, rocket enthusiasts and inventors began to appear in almost every country. Some people thought these early rocket pioneers were geniuses, and others thought they were crazy. Claude Ruggieri, an Italian living in Paris, apparently rocketed small animals into space as early as 1806. The payloads were recovered by parachute. As depicted here by artist Larry Toschik, French authorities were not always impressed with rocket research. They halted Ruggieri's plans to launch a small boy using a rocket cluster. (Reproduced from a drawing by Larry Toschik and presented here courtesy of the artist and Motorola Inc.)

  5. On Norbert Wiener on language

    NASA Astrophysics Data System (ADS)

    Julià, Pere

    2001-06-01

    Norbert Wiener (1948, 1950) subscribed to the traditional outlook on language as a formal object (L)—a system of forms and rules that can presumably be described in abstraction from speakers, listeners, and their interaction with the world and with themselves. Information and communication theories, which Wiener also pioneered, similarly reify the object of study in lieu of treating it as the natural phenomenon it obviously is. Terms like `input,' `output,' `message,' `transmission,' `processing,' etc. implicitly legitimize older views as to the use of language as a "tool" or "instrument" for expressing feelings, thoughts, ideas, etc.; more important yet, they stand in the way of a satisfactory account of self-referentiality, which finds its natural place within the broader context of self-regulation. Cybernetics may be said to have lost sight of the "kybernetes," which gave it its name. The ways in which language participates in—or even helps to integrate—the behavior of the total human individual in his/her adaptation to their milieu casts a new light on questions about self-organization, meaning, experience, and creativity.

  6. Forty Years On: Norbert Elias and the Young Worker Project. CLMS Working Paper.

    ERIC Educational Resources Information Center

    Goodwin, John; O'Connor, Henrietta

    A study performed in 1962 by Norbert Elias on the adjustment of young people to the transition from school to work had five areas of inquiry; adjustment to relationships with older workers and supervisors; adjustment to job problems; adjustment to role as workers; adjustment to role as money-earner in home relations; and adjustment to role as…

  7. Reconsidering Feminisms and the Work of Norbert Elias for Understanding Gender, Sport and Sport-Related Activities

    ERIC Educational Resources Information Center

    Mansfield, Louise

    2008-01-01

    This paper reconsiders the relationships between feminist perspectives and the figurational/process-sociological perspective of Norbert Elias for understanding gender, sport and sport-related activities. The main aim of the article is to respond to Colwell's claim that there are differences between feminist and figurational approaches to…

  8. A note about Norbert Wiener and his contribution to Harmonic Analysis and Tauberian Theorems

    NASA Astrophysics Data System (ADS)

    Almira, J. M.; Romero, A. E.

    2009-05-01

    In this note we explain the main motivations Norbert Wiener had for the creation of his Generalized Harmonic Analysis [13] and his Tauberian Theorems [14]. Although these papers belong to the most pure mathematical tradition, they were deeply based on some Engineering and Physics Problems and Wiener was able to use them for such diverse areas as Optics, Brownian motion, Filter Theory, Prediction Theory and Cybernetics.

  9. [Claude Bernard - then and now].

    PubMed

    Wise, Peter

    2017-01-01

    The early life of Claude Bernard - dreamer and frustrated playwright - reveals no indication of his future scientific aptitude. Cartesian doubt, a principle that he would adhere to lifelong, clouded a failed pharmacy apprenticeship that led to medical studies in Paris - but without great success. Research was his only aim, it was made possible only by a lucrative but unsuccessful arranged marriage. His passion for work and over-riding principles of truth and proof would ultimately allow him to stand out from his peers with recognition by multiple French professional societies - and the wider scientific world. In today's world, the two centuries-long practice of homeopathy illustrates his abhorrence of ''practice without proof'': a dominance by economic factors that is apparent in cancer chemotherapy, where new drug approval is often based on statistics rather than genuine clinical benefit. Bernard was indeed sceptical about the (ab)use of statistics - a caution even more necessary today. His experimental method stands out as a signal principle in research. This was cleverly taken out of context by Emile Zola, who used it to support his ideas on the literary naturalism that appeared in his Rougon-Macquart cycle of books - and that led him to dedicate his book, Le Roman Expérimental, to Claude Bernard himself. © Société de Biologie, 2017.

  10. Claude McKay: Black Protest in Western Traditional Form.

    ERIC Educational Resources Information Center

    Hudson-Weems, Clenora

    1992-01-01

    The protest poetry of Claude McKay, a leading writer of the Harlem Renaissance, is couched in the Western sonnet form. How the poetic form supports or conflicts with the messages of African-American pride and contempt for racism is examined. (SLD)

  11. In Memoriam: Claude Klee, M.D. | Center for Cancer Research

    Cancer.gov

    Claude Klee, M.D., a true giant among the many great biochemists at the National Institutes of Health (NIH), died on Monday, April 3, after suffering a heart attack. She was 85 years old.  Learn more...     

  12. Variability, Constraints, and Creativity: Shedding Light on Claude Monet.

    ERIC Educational Resources Information Center

    Stokes, Patricia D.

    2001-01-01

    Discusses how creative individuals maintain high levels of variability, examining how Claude Monet's habitually high level of variability in painting was acquired during his childhood and early apprenticeship and maintained throughout his adult career by a continuous series of task constraints imposed by the artist on his own work. For Monet,…

  13. Plant anesthesia supports similarities between animals and plants: Claude Bernard's forgotten studies.

    PubMed

    Grémiaux, Alexandre; Yokawa, Ken; Mancuso, Stefano; Baluška, František

    2014-01-01

    The French scientist Claude Bernard (1813-1878) is famous for his discoveries in physiology and for introducing rigorous experimental methods to medicine and biology. One of his major technical innovations was the use of chemicals in order to disrupt normal physiological function to test hypotheses. But less known is his conviction that the physiological functions of all living organisms rely on the same underlying principles. He hypothesized that similarly to animals, plants are also able to sense changes in their environment. He called this ability "sensitivity." In order to test his ideas, he performed anesthesia on plants and the results of these experiments were presented in 1878 in "Leçonssur les phénomènes de la vie communs aux animaux et aux végétaux." The phenomena described by Claude Bernard more than a century ago are not fully understood yet. Here, we present a short overview of anesthetic effects in animals and we discuss how anesthesia affects plant movements, seed germination, and photosynthesis. Surprisingly, these phenomena may have ecological relevance, since stressed plants generate anesthetics such as ethylene and ether. Finally, we discuss Claude Bernard's interpretations and conclusions in the perspective of modern plant sciences.

  14. [Two 150 years anniversaries: Claude Bernard's internal environment and Addison disease].

    PubMed

    Schreiber, V

    2005-01-01

    In 2005 two 150 years anniversaries, which essentially influenced the development of modern medicine will be celebrated. French physiologist Claude Bernard from College de France published his work "Lectures on Experimental Physiology, applied to medicine" and British medical doctor T. Addison described insufficiency of adrenal cortex, today known as Addison disease.

  15. Variability, constraints, and creativity. Shedding light on Claude Monet.

    PubMed

    Stokes, P D

    2001-04-01

    Recent experimental research suggests 2 things. The first is that along with learning how to do something, people also learn how variably or differently to continue doing it. The second is that high variability is maintained by constraining, precluding a currently successful, often repetitive solution to a problem. In this view, Claude Monet's habitually high level of variability in painting was acquired during his childhood and early apprenticeship and was maintained throughout his adult career by a continuous series of task constraints imposed by the artist on his own work. For Monet, variability was rewarded and rewarding.

  16. Children's Invented Notations and Verbal Responses to a Piano Work by Claude Debussy

    ERIC Educational Resources Information Center

    Elkoshi, Rivka

    2015-01-01

    This study considers the way children listen to classical music composed for them and the effect of age on their spontaneous invented notations and verbal responses. The musical selection is a piano piece for children by Claude Debussy:"'Jimbo's Lullaby" from "Children's Corner". Two hundred and nine children 4-9.5-years-old…

  17. [Claude Balme, a caregiver of the Egyptian expedition of Bonaparte (1766-1850)].

    PubMed

    Ségal, Alain

    2014-01-01

    The author explains military surgeon Balme's biograpyhy, especially during Bonaparte's Egyptian campaign (1798-1801). As there is some possible confusion with another Claude Balme, some archives deserve to be closely scrutinized. Through Balme's reports the author insists on his courageous part in several scurvy or plague epidemics. He was himself marked on his face; he ended his life in Lyons as a town-councillor.

  18. Open-cycle OTEC system performance analysis. [Claude cycle

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lewandowski, A.A.; Olson, D.A.; Johnson, D.H.

    1980-10-01

    An algorithm developed to calculate the performance of Claude-Cycle ocean thermal energy conversion (OTEC) systems is described. The algorithm treats each component of the system separately and then interfaces them to form a complete system, allowing a component to be changed without changing the rest of the algorithm. Two components that are subject to change are the evaporator and condenser. For this study we developed mathematical models of a channel-flow evaporator and both a horizontal jet and spray director contact condenser. The algorithm was then programmed to run on SERI's CDC 7600 computer and used to calculate the effect onmore » performance of deaerating the warm and cold water streams before entering the evaporator and condenser, respectively. This study indicates that there is no advantage to removing air from these streams compared with removing the air from the condenser.« less

  19. Composite turbine blade design options for Claude (open) cycle OTEC power systems

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Penney, T R

    1985-11-01

    Small-scale turbine rotors made from composites offer several technical advantages for a Claude (open) cycle ocean thermal energy conversion (OTEC) power system. Westinghouse Electric Corporation has designed a composite turbine rotor/disk using state-of-the-art analysis methods for large-scale (100-MW/sub e/) open cycle OTEC applications. Near-term demonstrations using conventional low-pressure turbine blade shapes with composite material would achieve feasibility and modern credibility of the open cycle OTEC power system. Application of composite blades for low-pressure turbo-machinery potentially improves the reliability of conventional metal blades affected by stress corrosion.

  20. Electronic Still Camera image of Astronaut Claude Nicollier working with RMS

    NASA Image and Video Library

    1993-12-05

    S61-E-006 (5 Dec 1993) --- The robot arm controlling work of Swiss scientist Claude Nicollier was photographed with an Electronic Still Camera (ESC), and down linked to ground controllers soon afterward. With the mission specialist's assistance, Endeavour's crew captured the Hubble Space Telescope (HST) on December 4, 1993. Four of the seven crew members will work in alternating pairs outside Endeavour's shirt sleeve environment to service the giant telescope. Electronic still photography is a relatively new technology which provides the means for a handheld camera to electronically capture and digitize an image with resolution approaching film quality. The electronic still camera has flown as an experiment on several other shuttle missions.

  1. The aesthetics of laboratory inscription: Claude Bernard's Cahier Rouge.

    PubMed

    Sattar, Atia

    2013-03-01

    This essay explores the aesthetic sensibilities of the French physiologist Claude Bernard (1813-1878). In particular, it analyzes the Cahier Rouge (1850-1860), Bernard's acclaimed laboratory notebook. In this notebook, Bernard articulates the range of his experience as an experimental physiologist, juxtaposing without differentiation details of laboratory procedure and more personal queries, doubts, and reflections on experimentation, life, and art. Bernard's insights, it is argued, offer an aesthetic and phenomenological template for considering experimentation. His physiological point of view ranges from his own bodily aesthesis or sensory perception, through personal reflections on scientific discovery as an artistic process, to a broader metaphysical conception of life as an artistic creation. Such an aesthetic approach to physiology enables Bernard to reconcile his empirical methodology and his romantic idealism; it offers the history of laboratory science a framework for considering the individual, bodily, and emotional labor inherent in physiological experimentation.

  2. Between the laboratory and the museum: Claude Bernard and the problem of time.

    PubMed

    Schmidgen, Henning

    2013-01-01

    This paper explores the relation between biological and historical time with respect to Claude Bernard's Lectures on the Phenomena of Life Common to Animals and Plants (1878). These lectures mirror Bernard's turn from the experimental physiology of animal organisms to a "general physiology" of elementary organisms, or cells, and discuss the problematic interrelation of science, life, and time. The paper argues that experimental life sciences in Bernard's sense are always also "living sciences," i.e., sciences in dynamic development. The perspectives of this conception are discussed with reference to Hans-Jörg Rheinberger's historical studies concerning the materiality and semiotics of "experimental systems."

  3. [Claude Perrault, famous architect, unknown physician, untiring researcher].

    PubMed

    Hazard, Jean

    2007-01-01

    As a famous architect Charles Perrault persuaded Colbert to appoint a committee of the "Bâtiments du Roi" made up of three persons: Le Vau, Le Brun and one of his brothers Claude whose Louis XIV chose the plan. While Le Vau was busy in Versailles Perrault's influence became dominating. Although he was an unknown medical practitioner he managed to be allowed to practise and to teach medicine and to be a member of theses' jury for twenty five years. He was highly regarded by his colleagues who did not hesitate to hold a consultation. His trip in Bordeaux was consecrated to look after his brother but because of his numerous occupations he gave up practising medicine and he only treated the members of his family, his friends and some poor. He was a tireless researcher and at the "Académie des Sciences" he looked after the "Histoire naturelle des animaux" (Natural History of the Animals). In "Les Essais de Physique" he tackled numerous problems of physiology such as elasticity and contractility of arteries, studied the sense organs and did some experiments about blood transfusion. As an exceptional man he could practise the three of the occupations.

  4. The Scriptural Cantatas "Esther" and "Jacob, et Rachel" of Elisabeth-Claude Jacquet de La Guerre: Historical Context and Performance Practice

    ERIC Educational Resources Information Center

    Buckley, Elizabeth M.

    2009-01-01

    This project explores two sacred cantatas of Elisabeth-Claude Jacquet de La Guerre, "Esther" and "Jacob, et Rachel". The cultural milieu in which the sacred cantatas of Jacquet de La Guerre were written and performed will be discussed, as well as possible venues for their original performances, including the Parisian salon, and…

  5. [Claude Bernard and the Comptes Rendus de la Société de Biologie: the movie of the physiological revolution by him who made it (1849-1878)].

    PubMed

    Hainaut, Jean

    2009-01-01

    Claude Bernard presented most of his fundamental results to the Société de Biologie, including proof of the modulation of the nervous system by the internal micromilieu. However, he did not describe the principle of a stable internal milieu as a condition for free life. Physiology, which is a part of biology, was not founded on cellular biology. Rather, Claude Bernard considered chemistry, anatomy and histology as the necessary auxiliary sciences for physiology. His articles are direct pictures, and not isolated ones, despite possible limitations, from a pre-montage movie of the physiological revolution he thought he had initiated, but not finished.

  6. Simulation and statistical analysis for the optimization of nitrogen liquefaction plant with cryogenic Claude cycle using process modeling tool: ASPEN HYSYS

    NASA Astrophysics Data System (ADS)

    Joshi, D. M.

    2017-09-01

    Cryogenic technology is used for liquefaction of many gases and it has several applications in food process engineering. Temperatures below 123 K are considered to be in the field of cryogenics. Extreme low temperatures are a basic need for many industrial processes and have several applications, such as superconductivity of magnets, space, medicine and gas industries. Several methods can be used to obtain the low temperatures required for liquefaction of gases. The process of cooling or refrigerating a gas to a temperature below its critical temperature so that liquid can be formed at some suitable pressure, which is below the critical pressure, is the basic liquefaction process. Different cryogenic cycle configurations are designed for getting the liquefied form of gases at different temperatures. Each of the cryogenic cycles like Linde cycle, Claude cycle, Kapitza cycle or modified Claude cycle has its own advantages and disadvantages. The placement of heat exchangers, Joule-Thompson valve and turboexpander decides the configuration of a cryogenic cycle. Each configuration has its own efficiency according to the application. Here, a nitrogen liquefaction plant is used for the analysis purpose. The process modeling tool ASPEN HYSYS can provide a software simulation approach before the actual implementation of the plant in the field. This paper presents the simulation and statistical analysis of the Claude cycle with the process modeling tool ASPEN HYSYS. It covers the technique used to optimize the liquefaction of the plant. The simulation results so obtained can be used as a reference for the design and optimization of the nitrogen liquefaction plant. Efficient liquefaction will give the best performance and productivity to the plant.

  7. Norbert Elias's motion pictures: history, cinema and gestures in the process of civilization.

    PubMed

    Algazi, Gadi

    2008-09-01

    Norbert Elias's project in The process of civilization (1939) involved reconstructing invisible movement--both the slow tempoof long-term historical change and the modification of psychic structures and embodied dispositions. To do this, he resorted to uncommon devices: treating historical texts as constituting a series amenable to a rudimentary discourse analysis, he constructed an imagined 'curve of civilization' serving as an approximation of the hidden process of change. Elias's curve was not supposed to represent single past states, but movement itself, its direction and pace. This novel concept of historical representation was related to the perception of cinema as a new medium making actual movement visible. But beyond making it possible to imagine how one could telescope long-term historical process, cinema also held the promise of serving as a microscope, making the minute movements of the human body, gestures and manners available for close inspection. While anthropologists were devising ways of using the new medium to document fleeting gestures and bodily postures, it was used by popular audiences as a source for remodelling behaviour and acquiring polite manners and body techniques, as noticed by such acute observers as Marcel Mauss and Joseph Roth. Hence, popular appropriation of the cinema gave rise to a heightened awareness of the historicity of gestures and the changing modalities of their transmission. Cinema was itself part of the accelerated motion of history, of a perceived change of pace in the process of civilization, which in its turn shed light on its historical antecedents and played an essential role in rethinking the notion of civilization and culture.

  8. Exergy analysis of helium liquefaction systems based on modified Claude cycle with two-expanders

    NASA Astrophysics Data System (ADS)

    Thomas, Rijo Jacob; Ghosh, Parthasarathi; Chowdhury, Kanchan

    2011-06-01

    Large-scale helium liquefaction systems, being energy-intensive, demand judicious selection of process parameters. An effective tool for design and analysis of thermodynamic cycles for these systems is exergy analysis, which is used to study the behavior of a helium liquefaction system based on modified Claude cycle. Parametric evaluation using process simulator Aspen HYSYS® helps to identify the effects of cycle pressure ratio and expander flow fraction on the exergetic efficiency of the liquefaction cycle. The study computes the distribution of losses at different refrigeration stages of the cycle and helps in selecting optimum cycle pressures, operating temperature levels of expanders and mass flow rates through them. Results from the analysis may help evolving guidelines for designing appropriate thermodynamic cycles for practical helium liquefaction systems.

  9. A case of undeclared debt? Claude Lévi-Strauss' ambiguities and paradoxes toward analytical psychology.

    PubMed

    Serina, Florent

    2018-06-09

    If his relationship to Sigmund Freud's psychoanalysis has been widely acknowledged, Claude Lévi-Strauss' rapport with C.G. Jung's analytical psychology remains quite obscure. While secondary commentary has been abundant, its approach has above all been intertextual, to the detriment of a rigorously historical reading. Even if certain arguments put forward by supporters of so-called "influence" deserve to be taken into account, especially because they highlight Lévi-Strauss ambiguities and paradoxes toward Jung, this paper provides proof that a precise reading of the texts, with the help of recent studies on the intellectual genesis of Lévi-Strauss, lead to reject the thesis of an unstated debt owed by the French anthropologist to the Zurich psychologist. © 2018 Wiley Periodicals, Inc.

  10. Ilya Neustadt, Norbert Elias, and the Leicester Department: personal correspondence and the history of sociology in Britain.

    PubMed

    Goodwin, John; Hughes, Jason

    2011-12-01

    The central aims of this paper are: (1) to explore the utility of using personal correspondence as a source of data for sociological investigations into the history of sociology in the UK; (2) in relation to this undertaking, to advance the beginnings of a figurational analysis of epistolary forms; and (3), to provide an empirically-grounded discussion of the historical significance of the Department of Sociology at the University of Leicester (a University largely ignored in 'standard histories' of the subject) at a formative phase in the development of the discipline within the UK. The correspondence drawn upon in the paper is between Norbert Elias and Ilya Neustadt between 1962 and 1964 when Elias was Professor of Sociology at the University of Ghana and Ilya Neustadt was Professor of Sociology and Head of the Sociology Department at the University of Leicester. From an analysis of this correspondence, we elucidate an emergent dynamic to the relationship between Neustadt and Elias, one which, we argue, undergirds the development of sociology at Leicester and the distinctive character of the intellectual climate that prevailed there during the 1960s. The paper concludes with a consideration of whether it was a collapse of this dynamic that led to a total breakdown in the relationship between Neustadt and Elias, and by extension, an important phase in the expansion of sociology at Leicester. © London School of Economics and Political Science 2011.

  11. [Claude Bernard, the experimental method, and the Société de Biologie].

    PubMed

    Bange, Christian

    2009-01-01

    Claude Bernard was one of the founder of the Société de Biologie created in 1849. He actively took part to it from its very beginning by presenting various communications and several important memoirs. Epistemological thoughts found in these memoirs lead to the methodological chapters introducing the volumes of his edited lessons given at the Collège de France. In 1865, these texts formed the basis to his Introduction à l'étude de la Médecine expérimentale, in which Bernard claims the experimental method should rely on the principle of determinism of the phenomena of Life. He was a dutiful President of the Société from 1867 until his death. He nevertheless was not often involved in debates, but agreed on the defense of the scientific principles he had claimed. He remained influential until his death, as noted in 1899 by the report Engène Gley wrote on the Société de Biologie during its fifty first years. Gley points regularly to Bernard's axioms which remained the true scientific credo of French biologists.

  12. Philosophical Basis and Some Historical Aspects of Systems Biology: From Hegel to Noble - Applications for Bioenergetic Research

    PubMed Central

    Saks, Valdur; Monge, Claire; Guzun, Rita

    2009-01-01

    We live in times of paradigmatic changes for the biological sciences. Reductionism, that for the last six decades has been the philosophical basis of biochemistry and molecular biology, is being displaced by Systems Biology, which favors the study of integrated systems. Historically, Systems Biology - defined as the higher level analysis of complex biological systems - was pioneered by Claude Bernard in physiology, Norbert Wiener with the development of cybernetics, and Erwin Schrödinger in his thermodynamic approach to the living. Systems Biology applies methods inspired by cybernetics, network analysis, and non-equilibrium dynamics of open systems. These developments follow very precisely the dialectical principles of development from thesis to antithesis to synthesis discovered by Hegel. Systems Biology opens new perspectives for studies of the integrated processes of energy metabolism in different cells. These integrated systems acquire new, system-level properties due to interaction of cellular components, such as metabolic compartmentation, channeling and functional coupling mechanisms, which are central for regulation of the energy fluxes. State of the art of these studies in the new area of Molecular System Bioenergetics is analyzed. PMID:19399243

  13. The Earth Summit: a vision shared. An interview with Jean-Claude Faby.

    PubMed

    Hoeffel, P H

    1992-01-01

    Interviewed by Development Forum, the director of UNCED's New York office, Jean-Claude Faby, who has been intimately involved in the negotiations preceding the Earth Summit, discusses his view of the process and expectations of global meeting. Faby explains that during the preparatory process, nongovernmental organizations (NGOs) have played an instrumental role. For example, women have raised issues concerning women, and their efforts are reflected in Agenda 21, the action plan of the Rio Declaration. Although describing the NGOs' critical assessment of the process as a health impatience, Faby notes that the issues to be confronted in Rio are some of the most complicated and vexing environmental and development problems facing the world community. Faby explains that the business community, an important player in the issues at hand, has also taken an active role in the negotiations. Faby acknowledges that the negotiations have witnessed a rift between North and South over the language of the document, a debate that will probably continue during the summit itself. Some of the issues of contention are military spending (a particularly concern of NGOs) and the North's high level of consumption, which the South insists must be addressed. Faby also discusses the issue of implementation and funding following the conclusion of the summit. Although implementation would require some $125 billion (a relatively modest figure), Faby expects that no neat funding package will emerge from Rio. In fact, funding will be one of the primary concerns of the Rio follow-up. Concerning the institutional follow-up of the summit, some are calling for the formation of a new institution, while others oppose such a move.

  14. Numerical studies on sizing/ rating of plate fin heat exchangers for a modified Claude cycle based helium liquefier/ refrigerator

    NASA Astrophysics Data System (ADS)

    Goyal, M.; Chakravarty, A.; Atrey, M. D.

    2017-02-01

    Performance of modern helium refrigeration/ liquefaction systems depends significantly on the effectiveness of heat exchangers. Generally, compact plate fin heat exchangers (PFHE) having very high effectiveness (>0.95) are used in such systems. Apart from basic fluid film resistances, various secondary parameters influence the sizing/ rating of these heat exchangers. In the present paper, sizing calculations are performed, using in-house developed numerical models/ codes, for a set of high effectiveness PFHE for a modified Claude cycle based helium liquefier/ refrigerator operating in the refrigeration mode without liquid nitrogen (LN2) pre-cooling. The combined effects of secondary parameters like axial heat conduction through the heat exchanger metal matrix, parasitic heat in-leak from surroundings and variation in the fluid/ metal properties are taken care of in the sizing calculation. Numerical studies are carried out to predict the off-design performance of the PFHEs in the refrigeration mode with LN2 pre-cooling. Iterative process cycle calculations are also carried out to obtain the inlet/ exit state points of the heat exchangers.

  15. Beyond Compassion: Children of Sex Workers in Kolkata's Sonagachi

    ERIC Educational Resources Information Center

    Sircar, Oishik; Dutta, Debolina

    2011-01-01

    In 2005, children of sex workers from Kolkata's Sonagachi red-light district formed their own collective, Amra Padatik ("We are Foot Soldiers"), to work for gaining dignity for their mothers and claiming their own rights as children of sex workers. In this article the authors speak to AP's founder members to demystify the culture of fear…

  16. 78 FR 17207 - Granting of Request for Early Termination of the Waiting Period Under the Premerger Notification...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-20

    .... 20130471 G Sun Pharmaceutical Industries Limited; Takeda Pharmaceutical Company Limited; Sun Pharmaceutical.... Martin, Ph.D.; Gilead Sciences, Inc.; John C. Martin, Ph.D. 20130547 G Jindal Poly Films Limited; Exxon... Norbert W. Bischofberger, Ph.D.; Gilead Sciences, Inc.; Norbert W. Bischofberger, Ph.D. 20130611 G...

  17. Learning to Mock--Challenging the Teaching Establishment

    ERIC Educational Resources Information Center

    Gabriel, Norman

    2016-01-01

    There have been very few studies that apply the work of Mikhail Bakhtin and Norbert Elias to understand the underlying learning processes of young children. This article will explore the methodological similarities between Bakhtin's ideas about the carnivalesque and Norbert Elias's theory of established-outsider relations to explain how young…

  18. Breast fat volume measurement using wide-bore 3 T MRI: comparison of traditional mammographic density evaluation with MRI density measurements using automatic segmentation.

    PubMed

    Petridou, E; Kibiro, M; Gladwell, C; Malcolm, P; Toms, A; Juette, A; Borga, M; Dahlqvist Leinhard, O; Romu, T; Kasmai, B; Denton, E

    2017-07-01

    To compare magnetic resonance imaging (MRI)-derived breast density measurements using automatic segmentation algorithms with radiologist estimations using the Breast Imaging Reporting and Data Systems (BI-RADS) density classification. Forty women undergoing mammography and dynamic breast MRI as part of their clinical management were recruited. Fat-water separated MRI images derived from a two-point Dixon technique, phase-sensitive reconstruction, and atlas-based segmentation were obtained before and after intravenous contrast medium administration. Breast density was assessed using software from Advanced MR Analytics (AMRA), Linköping, Sweden, with results compared to the widely used four-quartile quantitative BI-RADS scale. The proportion of glandular tissue in the breast on MRI was derived from the AMRA sequence. The mean unenhanced breast density was 0.31±0.22 (mean±SD; left) and 0.29±0.21 (right). Mean breast density on post-contrast images was 0.32±0.19 (left) and 0.32±0.2 (right). There was "almost perfect" correlation between pre- and post-contrast breast density quantification: Spearman's correlation rho=0.98 (95% confidence intervals [CI]: 0.97-0.99; left) and rho=0.99 (95% CI: 0.98-0.99; right). The 95% limits of agreement were -0.11-0.08 (left) and -0.08-0.03 (right). Interobserver reliability for BI-RADS was "substantial": weighted Kappa k=0.8 (95% CI: 0.74-0.87). The Spearman correlation coefficient between BI-RADS and MRI breast density was rho=0.73 (95% CI: 0.60-0.82; left) and rho=0.75 (95% CI: 0.63-0.83; right) which was also "substantial". The AMRA sequence provides a fully automated, reproducible, objective assessment of fibroglandular breast tissue proportion that correlates well with mammographic assessment of breast density with the added advantage of avoidance of ionising radiation. Copyright © 2017 The Royal College of Radiologists. All rights reserved.

  19. Geodiversity characterization and assessment of the Morainic Amphitheatre of Rivoli -Avigliana (NW-Italy)

    NASA Astrophysics Data System (ADS)

    Giordano, Enrico; Lucchesi, Stefania; Perotti, Luigi; Giardino, Marco

    2014-05-01

    The concept of Geodiversity in its wide sense refers specifically to particular geosystems that are in themselves complex (e.g diverse) assemblages of bedrock, landform, and soil features. Therefore, geodiversity assessment is strictly related to landscape structure, whose studies are in the field of complex Physical Geography. Moreover, Geodiversity studies provide a fundamental base for geoconservation and environmental management in a holistic way. This is particularly true within complex geomorphological environments, where many intrinsic and extrinsic factors are interconnected. Various procedures has been already applied for the creation of geodiversity maps in different geomorphological context, but especially in wide areas with a large geodiversity of landforms. Pleistocene morainic amphitheatres of the Alpine piedmont regions are indeed particular and complex environments: not only for the geological and geomorphological points of view, but also for their relationships with biotic components and human life. The aim of this study is to carry out a geodiversity characterization of the Rivoli-Avigliana Morainic Amphitheatre (AMRA; NW Italy). The AMRA separates the lower Susa Valley from the middle course of the Sangone River; it is a set of low hills and depressions related to glacial pulsations aged between 750,000 and 12,000 years ago. Earth Sciences knowledge of the area has been compared to detailed field geomorphological and territorial data in order to determine qualitative and quantitative landscape parameters and to evaluate their validity for geodiversity assessment. A first qualitative characterization of the AMRA and an estimation of its geodiversity have been performed by means of geomorphological mapping and stratigraphic studies, including geomorphosites assessment for the same area. Then, geodiversity characterization and evaluation have been performed through the definition and application of quantitative parameters (landform energy, slope

  20. [Social institutions and tempering of affects as "contraints" of social change. Norbert Elias' theory on the civilization theory in light of the biologic system theory of evolution].

    PubMed

    Weinich, Detlef

    2005-01-01

    This study is to be regarded as a contribution to interdisciplinary research and represents an attempt to clarify the question of whether and to what extent concepts that have been developed in the field of theoretical biology and which have a high degree of importance here can also be applied to sociological phenomena. In particular it is intended to examine the question of whether the civilizing process can be adequately treated using the evolutionary concept of "Constraints". This term, which has only recently been introduced into the discussion by PERE ALBERCH as an evolutionary factor, comprises all of the internal factors which influence the further course of the evolution of a system by ruling out certain possibilities, thus showing a limiting effect. Although "Constraints" go beyond the scope of Darwinian teachings about selection by the environment, they are increasingly accepted today as evolution factors by well-known exponents of Darwinian theory (cf. MAYNARD-SMITH 1985). The increase in popularity of "constraints" is also an expression of the rediscovery of a phenomenon which was originally expressed by RUPERT RIEDL and was introduced by him into German literature in the seventies. In the clarification of this question, special reference is made to the "theory of the civilizing process" by NORBERT ELIAS, since here a highly respected scholar has presented an important sociological theory. Moreover, there is such good scientific access to ELIAS because this author exemplifies his theses in historical terms and thus to a certain extent makes his explanations verifiable in scientific terms. In the treatment of this topic, the central terms and theses of ELIAS will be presented from the considerable scope of his work, and then illustrated with the help of several selected historical case studies. Furthermore, reference will be made at the relevant points to parallels and analogies which the works of ELIAS have to other, predominantly system

  1. Claude Bernard Distinguished Lecture. Becoming a truly helpful teacher: considerably more challenging, and potentially more fun, than merely doing business as usual.

    PubMed

    Jason, Hilliard

    2007-12-01

    Few medical faculty members are adequately prepared for their instructional responsibilities. Our educational traditions were established before we had research-based understandings of the teaching-learning process and before brain research began informing our understandings of how humans achieve lasting learning. Yet, there are several advantages you may have. If your expertise is at one of the frontiers of human biology, your teaching can be inherently fascinating to aspiring health professionals. If your work has implications for human health, you have another potential basis for engaging future clinicians. And, thanks to Claude Bernard's influence, you likely are "process oriented," a necessary mindset for being an effective teacher. There are also challenges you may face. Your medical students will mostly become clinicians. Unless you can help them see connections between your offerings and their future work, you may not capture and sustain their interest. To be effective, teachers, like clinicians, need to be interactive, make on-the-spot decisions, and be "emotional literate." If you aren't comfortable with these demands, you may have work to do toward becoming a truly helpful teacher. Program changes may be needed. Might your program need to change 1) from being adversarial and controlling to being supportive and trust based or 2) from mainly dispensing information to mainly asking and inviting questions? In conclusion, making changes toward becoming a truly helpful teacher can bring benefits to your students while increasing your sense of satisfaction and fulfillment as a teacher. If you choose to change, be gentle with yourself, as you should be when expecting your students to make important changes.

  2. Teaching and Learning in the Interactive Classroom

    ERIC Educational Resources Information Center

    Silverthorn, D. U.

    2006-01-01

    The Claude Bernard Distinguished Lectureship of the Teaching of Physiology Section is presented annually at the Experimental Biology meeting. The lectureship is named for Prof. Claude Bernard, the experimental physiologist who is credited with introducing the concept of homeostasis. The 2006 Claude Bernard Distinguished Lecture was given by Dr.…

  3. Revista de Documentacao de Estudos em Linguistica Teorica e Aplicada (DELTA): Novos Estudos em Gamatica Gerativa (Journal of Documentary Studies in Theoretical and Applied Linguistics [DELTA]: New Studies in Generative Grammar).

    ERIC Educational Resources Information Center

    Revista de Documentacao de Estudos em Linguistica Teorica e Aplicada, 2000

    2000-01-01

    This issue contains the following articles: "Resumption and Last Resort" (Joseph Aoun); "Existentials, A-Chains, and Reconstruction" (Norbert Hornstein); "How Long Was the Nineteenth Century" (David Lightfoot); "Formal Features and Parameter Setting: A View From Portuguese Past Participles and Romance Future…

  4. Thermodynamic design of natural gas liquefaction cycles for offshore application

    NASA Astrophysics Data System (ADS)

    Chang, Ho-Myung; Lim, Hye Su; Choe, Kun Hyung

    2014-09-01

    A thermodynamic study is carried out for natural gas liquefaction cycles applicable to offshore floating plants, as partial efforts of an ongoing governmental project in Korea. For offshore liquefaction, the most suitable cycle may be different from the on-land LNG processes under operation, because compactness and simple operation are important as well as thermodynamic efficiency. As a turbine-based cycle, closed Claude cycle is proposed to use NG (natural gas) itself as refrigerant. The optimal condition for NG Claude cycle is determined with a process simulator (Aspen HYSYS), and the results are compared with fully-developed C3-MR (propane pre-cooled mixed refrigerant) JT cycles and various N2 (nitrogen) Brayton cycles in terms of efficiency and compactness. The newly proposed NG Claude cycle could be a good candidate for offshore LNG processes.

  5. Pure Red Cell Aplasia After Chemotherapy for Hodgkin’s Lymphoma: In Vitro Evidence for T Cell Mediated Suppression of Erythropoiesis and Response to Sequential Cyclosporin and Erythropoietin

    DTIC Science & Technology

    1994-01-01

    serologies revealed no evidence of recent or active parvovirus , hepatitis A, B, C, or Immunophenotyping studies on peripheral blood lym- Epstein-Barr...impair erythropoietin production in humans [27-291 and Norbert Frickhofer for the B 19 parvovirus studies and in mice [301. As was documented

  6. JPRS Report, East Europe

    DTIC Science & Technology

    1991-02-01

    claims in order, monetize the property of the government enterprise as quickly and efficiently as possible, or dispose of it in accordance with...bank withheld credit and one of the halls was not completed. Shortly afterward, Mr. Claude Flauraud, director of development and export sales for...perish." Claude Flauraud came to Lodz three times. During one of the meetings, when Strug’s former liquidator was late, Flauraud heard the following

  7. Overview 2010 of ARL Program on Network Science for Human Decision Making

    DTIC Science & Technology

    2011-01-01

    pressure and subliminal seduction; but always through a sequence of decisions, either conscious or not. Network characteristics cannot be deduced from the...Time, Communication , and the Nervous System”, in Norbert Wiener: Collected Works, Volume IV, pp.220-252, The MIT Press, Cambridge, MA (1985). 16. P

  8. Identifying Configurations of Higher Education: Reflections on Concepts That Compare Complex Cultural Settings

    ERIC Educational Resources Information Center

    Alheit, Peter

    2013-01-01

    This paper examines the idea of qualitative comparing in order to create a "heuristic concept" that will enable relational structures to be examined, drawing on the sociological tradition founded by Norbert Elias. Subsequently, an empirical research example -- the comparison of three "mentality spaces" in post-socialist…

  9. "Una Communita" Poco Nota della Communicazione non Verbale: Come Communicano il Direttore e l'Orchestra (A Little Known "Community" of Nonverbal Communication: How the Conductor and Orchestra Communicate).

    ERIC Educational Resources Information Center

    Leonardi, Magda Farago

    1992-01-01

    Examines how conductors and orchestras communicate. Communication is essentially nonverbal. Conductors use gestures, gaze, facial expression, nods and posture to deliver their message. Norbert Weiner's Cybernetic Theory of human communication is seen as a means of analyzing precisely how this musical communication takes place. (16 references) (LET)

  10. DC Voltage Interface Standards for Naval Applications

    DTIC Science & Technology

    2015-06-24

    norbert.doerry@navy.mil Dr. John Amy Naval Sea Systems Command United States Navy Washington DC , USA john.amy@navy.mil Abstract—. MIL-STD-1399...standards have been established for DC interfaces on U.S. naval surface ships. This paper provides recommendations for specific standard DC

  11. Internationalization, Globalization and Relationship Networks as an Epistemological Framework Based on Comparative Studies in Education

    ERIC Educational Resources Information Center

    García, Amelia Molina; Lara, José Luis Horacio Andrade

    2016-01-01

    In this paper we present some thoughts on the epistemological framework of comparative studies in education. We present some concepts on the internationalization, globalization and inter-relation networks, based on Jürgen Schriewer, Immanuel Wallerstein, and Norbert Elias's theoretical concepts. These reflections were built within the framework of…

  12. Using Agent Based Distillation to Explore Issues Related to Asymmetric Warfare

    DTIC Science & Technology

    2009-10-01

    hierarchical model of needs proposed by Abraham Maslow [12]. An interpretation of Maslow’s hierarchy of needs can be represented as a pyramid with the more...D. Kahnemann, E. Deiner, Dr. Phil Norbert Schwarz, « Foundations of Hedonic Psychology », Russell Sage Foundation, 1999 [12] Abraham.H. Maslow

  13. Aurora-A as a Modifier of Breast Cancer Risk in BRCA 1/2 Mutation Carriers

    DTIC Science & Technology

    2007-06-01

    Dieter Schaefer, Institute of Human Genetics, University of Frankfurt, Frankfurt, Germany; Norbert Arnold, University of Schleswig- Holstein , Campus...Intron 2 Opossum Mouse Rat Cow Dog Intron 1 Figure 3 | The FGFR2 locus. a, Map of the whole FGFR2 gene, viewed relative to common SNPs on HapMap

  14. Adult and Child Identities in Irish Primary Schools, c.1830-1909

    ERIC Educational Resources Information Center

    Dolan, Paddy

    2016-01-01

    Drawing on teaching manuals, government reports and school inspectors' reports from the 1830s up to the early twentieth century, this paper traces the changing conceptual and social distance between childhood and adulthood in Ireland. Using Norbert Elias's figurational approach, it is argued that children became increasingly involved in both…

  15. Self-Enhancing Seminars and Experiential Journals for Cooperating Teachers: A Professional Growth Model.

    ERIC Educational Resources Information Center

    Hauser, Jerald; Zimmerman, Gloria

    Since 1989, professional growth seminars at St. Norbert College (Wisconsin) have brought cooperating teachers together to share their thoughts and emotions related to the experience of student teacher mentoring. In these seminars, the mentors gather for mutual instruction and support. Each seminar series consists of six 2-hour meetings during a…

  16. Simplified Helium Refrigerator Cycle Analysis Using the `Carnot Step'

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    P. Knudsen; V. Ganni

    2006-05-01

    An analysis of the Claude form of an idealized helium liquefier for the minimum input work reveals the ''Carnot Step'' for helium refrigerator cycles. As the ''Carnot Step'' for a multi-stage polytropic compression process consists of equal pressure ratio stages; similarly for an idealized helium liquefier the ''Carnot Step'' consists of equal temperature ratio stages for a given number of expansion stages. This paper presents the analytical basis and some useful equations for the preliminary examination of existing and new Claude helium refrigeration cycles.

  17. Configurations of Activity: From the Coupling of Individual Actions to the Emergence of Collective Activity. A Study of Mathematics Teaching Situation in Primary School

    ERIC Educational Resources Information Center

    Veyrunes, Philippe; Gal-Petitfaux, Nathalie; Durand, Marc

    2009-01-01

    This article presents and uses the notion of configuration of activity, which extends the Norbert Elias's original concept of social configuration based on the study and analysis of individual and collective activity. Although this concept embraces all types of social activities, in the present study the authors used it to describe and analyse…

  18. The Pragmatist Reader: Reading as a Meaning-Making Transaction in the English Classroom

    ERIC Educational Resources Information Center

    Taylor, Stephen

    2011-01-01

    Rosenblatt's transactional theory and Pike's aesthetic model of reading both put the reader at the heart of the reading transaction. A re-envisionment of these approaches in terms of the pragmatist reader, a concept derived from Norbert Wiley's "pragmatism's self" and the findings of a recent case study into classroom reading, leads to a…

  19. Transitioning Technology to Naval Ships

    DTIC Science & Technology

    2010-06-18

    GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Dr. Norbert Doerry 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING...6.3.3 Evaluation of IPS and NGIPS........................................................................................ 48 6.4 Set Based Design on...56 7.2 Employ More Robust Metrics........................................................................................... 57 7.2.1 Knowledge

  20. The Body's Civilisation/Decivilisation: Emotional, Social, and Historical Tensions

    ERIC Educational Resources Information Center

    Veiga, Cynthia

    2018-01-01

    In this article, I discuss the paradoxes of the body's civilising processes in dialogue with Norbert Elias's sociological theory. As a premise, I contend that modernity's civilising rationality has taken the body, the senses, and emotions in such a fragmented manner that we sometimes lose sight of the dimension that body and person are…

  1. Bilingual Competence and Bilingual Proficiency in Child Development

    ERIC Educational Resources Information Center

    Francis, Norbert

    2011-01-01

    When two or more languages are part of a child's world, we are presented with a rich opportunity to learn something about language in general and about how the mind works. In this book, Norbert Francis examines the development of bilingual proficiency and the different kinds of competence that come together in making up its component parts. In…

  2. The Sonnet Tradition and Claude McKay

    ERIC Educational Resources Information Center

    Denize, Donna E. M.; Newlin, Louisa

    2009-01-01

    This year marks the 400th anniversary of the publication of the first edition of Shakespeare's 154 sonnets--an excellent moment to focus on them, as well as on those written by others before and after 1609. Because these authors share an enthusiasm for poetry in general and the sonnet in particular, they want to encourage teachers to include…

  3. Premixed Turbulent Combustion in High Reynolds Number Regimes of Thickened Flamelets and Distributed Reactions

    DTIC Science & Technology

    2016-03-24

    thickened preheat (TP) regime that is bounded by the Klimov-Williams limit, (b) the broken reaction layers (BR) boundary and the partially-distributed...b) the broken reaction layers (BR) boundary that is bounded by Norbert Peters predicted limit, and the partially-distributed reactions (PDR...Nomenclature BR = broken reaction layer boundary DR = distributed reaction zone boundary Ka = Karlovitz number of Peters (Eq. 1) equal to (δF,L

  4. Plant anesthesia supports similarities between animals and plants

    PubMed Central

    Grémiaux, Alexandre; Yokawa, Ken; Mancuso, Stefano; Baluška, František

    2014-01-01

    The French scientist Claude Bernard (1813–1878) is famous for his discoveries in physiology and for introducing rigorous experimental methods to medicine and biology. One of his major technical innovations was the use of chemicals in order to disrupt normal physiological function to test hypotheses. But less known is his conviction that the physiological functions of all living organisms rely on the same underlying principles. He hypothesized that similarly to animals, plants are also able to sense changes in their environment. He called this ability “sensitivity.” In order to test his ideas, he performed anesthesia on plants and the results of these experiments were presented in 1878 in “Leçonssur les phénomènes de la vie communs aux animaux et aux végétaux.”1 The phenomena described by Claude Bernard more than a century ago are not fully understood yet. Here, we present a short overview of anesthetic effects in animals and we discuss how anesthesia affects plant movements, seed germination, and photosynthesis. Surprisingly, these phenomena may have ecological relevance, since stressed plants generate anesthetics such as ethylene and ether. Finally, we discuss Claude Bernard's interpretations and conclusions in the perspective of modern plant sciences. PMID:24476640

  5. Seaworthy Quantum Key Distribution Design and Validation (SEAKEY)

    DTIC Science & Technology

    2015-08-07

    absorption and scattering using MODTRAN [ Berk et al.]. Thus, channel efficiency is expressed as follows: G=GT×exp[−αL], (10) where exp[−αL] is...34 New Journal of Physics 13, 013003 (2011). [Scarani et al.] Valerio Scarani, Helle Bechmann-Pasquinucci, Nicolas J . Cerf, Miloslav Dušek, Norbert...050303 (2005). [Renner and Cirac] R. Renner and J . I. Cirac, de Finetti representation theorem for infinite-dimensional quantum systems and

  6. Promising New High-Explosives: Triaminoguanidinium (TAG) and Dinitramide (DN) Salts

    DTIC Science & Technology

    2008-12-01

    1 PROMISING NEW HIGH- EXPLOSIVES : TRIAMINOGUANIDINIUM (TAG) AND DINITRAMIDE (DN) SALTS Thomas M. Klapötke,* Norbert Mayr, L.d.R. and Jörg...Me-AtNO2, 4) shows great explosion performance and may be an alternative to commonly used and toxic RDX. An improved synthesis for the promising...Including the good thermal stability 9 could be an alternative to RDX as a high explosive . In addition, the thermal behavior under confinement and the

  7. Out of a creative jumble of ideas in the middle of last Century: Wiener, interdisciplinarity, and all that.

    PubMed

    Montagnini, Leone; Tabacchi, Marco Elio; Termini, Settimo

    2016-01-01

    Is Biophysics an interdisciplinary science? In order to answer this rhetorical question, it can be useful to look back at history of disciplines, as well as that of the scientific institutions helping their development. In this contribution some aspects of the unusual hodgepodge of concepts involving Biophysics, the legacy of Cybernetics, cognitive science and the central figure of Norbert Wiener are presented and discussed. Copyright © 2015 Elsevier B.V. All rights reserved.

  8. Proper-Motion Study of the Magellanic Clouds Using SPM Material

    DTIC Science & Technology

    2010-12-01

    F. VAN ALTENA I, NORBERT ZACHARIAS2, DANA I. CASETTI-DINESCU I, VLADIMIR I. KORCHAGIN I, iMANTSPLATAIS3, DAVID G. MONE -r4, CARLOS E. LOPEZ5, DAVID...difference of the two clouds to within ±54 km S-I. The absolute proper-motion results are consistent with the Clouds’ orbits being marginally bound...consistent with the Clouds’ orbits being marginally bound to the Milky Way, albeit on an elongated orbit. The inferred relative velocity between the

  9. Experimental Comparison of Two Quantum Computing Architectures

    DTIC Science & Technology

    2017-03-28

    IN A U G U RA L A RT IC LE CO M PU TE R SC IE N CE S Experimental comparison of two quantum computing architectures Norbert M. Linkea,b,1, Dmitri...the vast computing power a universal quantumcomputer could offer, several candidate systems are being explored. They have allowed experimental ...existing systems and the role of architecture in quantum computer design . These will be crucial for the realization of more advanced future incarna

  10. Me, myself, and I: the rise of the modern self.

    PubMed

    Hanna, Robert; Izenberg, Gerald; Martin, Raymond; Wiley, Norbert; Seigel, Jerrold

    2011-10-01

    Moderated by Robert Hanna (University of Colorado), historians Gerald Izenberg (Washington University, St. Louis) and Jerrold Seigel (New York University), philosopher Raymond Martin (University of Maryland and Union College), and sociologist Norbert Wiley (University of Illinois) trace the evolution of the meaning of self from antiquity to the present and consider how the self described by classical philosophers matches the reality of what we know about ourselves from human experience and research. © 2011 New York Academy of Sciences.

  11. [52th Commemoration of French Journal of Plastic Aesthetic Surgery (1956-2007). Fifty-four years of editorial; five Editors-in-chief].

    PubMed

    Cariou, J-L

    2007-08-01

    The french Society of Plastic Reconstructive and Aesthetic Surgery (SOF.CPRE) is born December 3th 1952. Initially without "aesthetic", this "key-word" is agreed in 1983 and the symbols are advanced since: SFCPR, SFCPRE, SOF.CPRE. Its official organ, formerly included in Annales de chirurgie (1954-1955), become Annales de chirurgie plastique in 1956, Annales de chirurgie plastique et esthétique in 1983 and finally Annales de chirurgie plastique esthétique (ACPE) in 1992. Since the origin, five Editors-in-chief succeded: Claude Dufourmentel, Raymond Vilain, Jean-Pierre Lalardrie, Claude Lê-Quang, Jean-Luc Cariou. Four of them are alive, Raymond Vilain is dead. The author relate here the natural story of these five editors who had all a triple route: personnal, surgical and editorial.

  12. Great Help for Older Americans | NIH MedlinePlus the Magazine

    MedlinePlus

    ... that may prevent or delay disability. Claude D. Pepper Older American Independence Centers (OAICs) University of California ... Wake Forest University P.I. Stephen Kritchevsky, PhD Pepper Coordinating Center Kevin High, MD University of Florida ...

  13. The ARGO Project: assessing NA-TECH risks on off-shore oil platforms

    NASA Astrophysics Data System (ADS)

    Capuano, Paolo; Basco, Anna; Di Ruocco, Angela; Esposito, Simona; Fusco, Giannetta; Garcia-Aristizabal, Alexander; Mercogliano, Paola; Salzano, Ernesto; Solaro, Giuseppe; Teofilo, Gianvito; Scandone, Paolo; Gasparini, Paolo

    2017-04-01

    ARGO (Analysis of natural and anthropogenic risks on off-shore oil platforms) is a 2 years project, funded by the DGS-UNMIG (Directorate General for Safety of Mining and Energy Activities - National Mining Office for Hydrocarbons and Georesources) of Italian Ministry of Economic Development. The project, coordinated by AMRA (Center for the Analysis and Monitoring of Environmental Risk), aims at providing technical support for the analysis of natural and anthropogenic risks on offshore oil platforms. In order to achieve this challenging objective, ARGO brings together climate experts, risk management experts, seismologists, geologists, chemical engineers, earth and coastal observation experts. ARGO has developed methodologies for the probabilistic analysis of industrial accidents triggered by natural events (NA-TECH) on offshore oil platforms in the Italian seas, including extreme events related to climate changes. Furthermore the environmental effect of offshore activities has been investigated, including: changes on seismicity and on the evolution of coastal areas close to offshore platforms. Then a probabilistic multi-risk framework has been developed for the analysis of NA-TECH events on offshore installations for hydrocarbon extraction.

  14. Open-cycle systems performance analysis programming guide

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Olson, D.A.

    1981-12-01

    The Open-Cycle OTEC Systems Performance Analysis Program is an algorithm programmed on SERI's CDC Cyber 170/720 computer to predict the performance of a Claude-cycle, open-cycle OTEC plant. The algorithm models the Claude-cycle system as consisting of an evaporator, a turbine, a condenser, deaerators, a condenser gas exhaust, a cold water pipe and cold and warm seawater pumps. Each component is a separate subroutine in the main program. A description is given of how to write Fortran subroutines to fit into the main program for the components of the OTEC plant. An explanation is provided of how to use the algorithm.more » The main program and existing component subroutines are described. Appropriate common blocks and input and output variables are listed. Preprogrammed thermodynamic property functions for steam, fresh water, and seawater are described.« less

  15. STS-103 Photo-op/Suit-up/Depart O&C/Launch Discovery On-Orbit/Landing/Crew Egress

    NASA Technical Reports Server (NTRS)

    2001-01-01

    The crew of the STS-103 space mission are shown as they prepare for launch and landing of the space shuttle discovery. The crew includes: Commander Curtis L. Brown, Pilot Scott J. Kelly, and Mission Specialists: Steven L. Smith, C. Michael Foale, John M. Grunsfeld, Claude Nicollier and Jean-francois Clervoy. Footage of these astronauts during suit-up, Ingress, Egress and Operations and Checkout (O&C) is presented. Live footage of the countdown and launch of the space shuttle discovery is shown from various vantage points such as the Tower 1, Vehicle Assembly Building (VAB), and pad perimeter. Once in orbit, a presentation of Steven Smith, John Grunsfield, Michael Foale and Claude Nicollier performing three spacewalks to repair the HST is shown. The landing of the space shuttle discovery at the Kenndy Space Center is shown.

  16. International outlook - Partial victory simply not good enough.

    PubMed

    Williams, Susan

    2014-11-27

    IT IS rare that the question of who should lead health policy in the European Commission receives UK media coverage. But after incoming president Jean-Claude Juncker announced the portfolios of his fellow European commissioners in September, alarm bells were ringing.

  17. 78 FR 47489 - Unblocking of Specially Designated Nationals and Blocked Persons Pursuant to the Foreign...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-05

    ...; c/o INVERPUNTO DEL VALLE S.A., Cali, Colombia; c/o INVERSIONES CIFUENTES Y CIA. S. EN C., Medellin...: INVERPUNTO DEL VALLE S.A.; Linked To: INVERSIONES CIFUENTES Y CIA. S. EN C.; Linked To: LE CLAUDE, S.A. DE C...

  18. 75 FR 10789 - Appointments to Performance Review Board for Senior Executive Service

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-09

    ... Executive Service employees: Perry E. Anthony, Ph.D., Deputy Commissioner, Rehabilitation Services Administration, Department of Education. Abram Claude, Jr., Private Citizen Paul M. Laird, Assistant Director, Industries, Education and Vocational Training and Chief Operating Officer/FPI, Department of Justice. All...

  19. Actes des Journees de linguistique (Proceedings of the Linguistics Conference) (12th, Quebec City, Canada, March 26-27, 1998).

    ERIC Educational Resources Information Center

    Boissonneault, Chantal, Ed.

    Papers on language research include: "L'expression de l'opposition en Latin" ("The Expression of Opposition in Latin" (Claude Begin); "Le francais de l'Abitibi: characteristiques phonetiques et origine socio-geographique des locuteurs" ("The French of Abitibi: Phonetic Characteristics and Socio-Geographic Origin…

  20. Survey of Neural Net Paradigms for Specification of Discrete Networks.

    DTIC Science & Technology

    1988-01-31

    special applications, such as 3-d imaging, scene segmentation, temporal imaging models, nor phonological analysis of speech. The cost of problem...Nov. 1985. ., .U U - - A 1 Bibliography Berge, Claude, "Principles of Combinatorics", Academic Press, 1971 Fischer, Roland, " Deconstructing Reality

  1. [The nineteenth century roots of the contemporary biological revolution].

    PubMed

    Swynghedauw, Bernard

    2006-01-01

    The recent publication of the human genomic sequence is the most important progress in biology. It originates from four major watersheds between 1860-1865, namely the biological evolution by Darwin in 1858, the Mendel laws of heredity in 1865, the basis of physiology established by Claude Bernard also in 1865, and the discoveries of microbacteria by Louis Pasteur around 1857. Before 1860, biology did not exist as a science. After 1860, the Darwin's theory progressively became a law after the discovery of the DNA polymorphism and that of the mechanisms of genetic mixing. So far the Mendel's laws were confirmed in parallel with the development of molecular genetics after the discovery of DNA structure and genetic code. The discovery of hormones is one example, amongst several on how integrative physiology applies to Claude Bernard's basis. Finally, based on Pasteur's discovery and Pasteur Institutes, microbiology became a tool for molecular biologists.

  2. The Loneliness of the Aging in Two Contemporary Novels.

    PubMed

    Oró-Piqueras, Maricel

    2016-04-01

    In The Loneliness of the Dying (1985), sociologist Norbert Elias claims that "aging" and "old age" have become frightening, almost taboo terms in Western society because death is increasingly made invisible in advanced societies. Years ago, death was a part of life and the dead were granted the honor of passing away in their homes, surrounded by their communities; in present-day society, most have never seen a corpse and are ignorant of anything related to death. According to Elias, the consequences of this distancing from death have been a distancing from the aging process as a whole. This paper aims to analyze to what extent Norbert Elias's theories about death and the aging process are reflected in contemporary British fiction, using two novels as case studies. Ending Up (1974) and These Foolish Things (2004) depict older British characters who decide to share their last years when they realize that they are increasingly forgotten and invisible both within their communities and their families. In each of their particular styles, bleak and ironic in the case of Kingsley Amis's Ending Up, and refreshingly humorous and moving in the case of Deborah Moggach's These Foolish Things, both authors reflect on possible outcomes for an increasingly aging population. © The Author 2014. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  3. Shades of Monet.

    ERIC Educational Resources Information Center

    Baber, Bonnie

    1999-01-01

    Presents an art lesson for elementary students using painter Claude Monet as an introduction to Impressionism. Discusses Monet and his artwork. Explains that the students copy Monet's painting "The House of Parliament, Sunset" in order to draw the contour or outline of the buildings. (CMK)

  4. A Monet Garden Installation: A Momentary Gift of Art.

    ERIC Educational Resources Information Center

    McGonigle, Kathleen

    2002-01-01

    Discusses art lessons where students created a three-dimensional rendering of Claude Monet's gardens using the Impressionist style. Focused on teaching students about art history, Impressionistic art, and installation of art. Addresses the goals of the lesson and the process of creating the art. (CMK)

  5. Promoting Learning for Culturally and Linguistically Diverse Students. Classroom Applications from Contemporary Research.

    ERIC Educational Resources Information Center

    Gersten, Russell M.; Jimenez, Robert T.

    This collection of essays is designed to help teachers of linguistically and culturally diverse students address their students' needs effectively. Essays include: "A Balanced Approach to Early Spanish Literacy Instruction" (Claude Goldenberg); "Language and Preliteracy Development of English as a Second Language Learners in Early…

  6. Hearing on H.R. 670, The School Completion and Incentives Act. Hearing before the Subcommittee on Elementary, Secondary, and Vocational Education of the Committee on Education and Labor. House of Representatives, One Hundred First Congress, First Session (Miami, Florida).

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. House Committee on Education and Labor.

    This document presents witness testimony and prepared statements from the Congressional hearing. Statements are included from Representatives Claude Pepper, Carl Perkins, Charles Hayes, and Nick Rahall. Witnesses providing testimony include: (1) Joseph Fernandez, Superintendent of Dade County Public Schools, Florida; (2) Nan Rich, who describes…

  7. Gender, Stereotype Threat, and Anxiety: Psychophysiological and Cognitive Evidence

    ERIC Educational Resources Information Center

    Osborne, Jason W.

    2006-01-01

    Introduction: Claude Steele's stereotype threat hypothesis proposed that negative group stereotypes increase individual anxiety levels, hurting performance. However, the role of anxiety in stereotype threat has not been fully explored. This study examined the hypothesis that experimental manipulation of stereotype threat would influence real-time…

  8. NextGen Avionics Roadmap Version 1.0

    DTIC Science & Technology

    2008-10-24

    monetized benefit streams when available. Since the source analyses had been conducted at different times using a range of operational and economic...Mrkoci BAE Systems Dave Nakamura Boeing Rob Pappas FAA Dharmesh Patel Honeywell Art Politano FAA Jean- Claude Richard Thales Avionics Brian E. Smith

  9. Peut-on ne pas etre eclectique? (Can We Not Be Eclectic?)

    ERIC Educational Resources Information Center

    Le Goffic, Pierre

    1977-01-01

    An interview with Jean-Claude Chevalier in which the advantages and dangers of eclecticism are discussed. Some topics covered are: the role of traditional grammar; recent linguistic research in French; the development of teaching methods; Chomsky's theory of universal grammar. (Text is in French.) (AMH)

  10. EURYDICE Seminar on the Role of School Heads in Education Systems. Main Speeches. (Paris, France, June 29, 1995).

    ERIC Educational Resources Information Center

    EURYDICE European Unit, Brussels (Belgium).

    Three speeches from a seminar include: (1) "Introductory Statement" (Antoine Bousquet); (2) "Objectives and Reforms of the French Education System" (Claude Thelot); and (3) "School Heads in the French Education System" (Louis Baladier). The seminar program and a list of participants also are included. (EH)

  11. A Physiologist's View of Homeostasis

    ERIC Educational Resources Information Center

    Modell, Harold; Cliff, William; Michael, Joel; McFarland, Jenny; Wenderoth, Mary Pat; Wright, Ann

    2015-01-01

    Homeostasis is a core concept necessary for understanding the many regulatory mechanisms in physiology. Claude Bernard originally proposed the concept of the constancy of the "milieu interieur," but his discussion was rather abstract. Walter Cannon introduced the term "homeostasis" and expanded Bernard's notion of…

  12. HMO's and Medicare: Problems in the Oversight of a Promising Partnership. Hearing before the Subcommittee on Health and Long-Term Care of the Select Committee on Aging. House of Representatives, Ninety-Ninth Congress, First Session.

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. House Select Committee on Aging.

    This document contains witness testimonies and prepared statements from the Congressional hearing called to examine problems in the partnership of Medicare and Health Maintenance Organizations (HMO's). Opening statements are included from committee chairman Claude Pepper and from Representative Lawrence J. Smith. Two panels of witnesses address…

  13. Catastrophic Health Insurance: The Tennessee Perspective. Hearing before the Subcommittee on Health and Long-Term Care of the Select Committee on Aging. House of Representatives, Ninety-Ninth Congress, Second Session (Chattanooga, Tennessee).

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. House Select Committee on Aging.

    This document contains witnesses' testimonies and prepared statements from the Congressional hearing held in Chattanooga, Tennessee to gain that state's perspective on catastrophic health insurance. Opening statements are included from Representatives Marilyn Lloyd and Claude Pepper. Two panels of witnesses provide testimony. The first panel,…

  14. Federal Drug Law Enforcement and Interdiction. Hearing before the Select Committee on Narcotics Abuse and Control. House of Representatives, Ninety-Eighth Congress, Second Session, May 22, 1984.

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. House Select Committee on Narcotics Abuse and Control.

    This document contains testimony and prepared statements from the Congressional hearing on federal drug law enforcement. Statements are given from Congressman Claude Pepper, the staff director of the National Narcotics Border Interdiction System (NNBIS), an administrator from the Drug Enforcement Administration (DEA), a commissioner from the…

  15. Poststructuralism as Theory and Practice in the English Classroom. ERIC Digest.

    ERIC Educational Resources Information Center

    Bush, Harold K., Jr.

    This digest provides a historical review of some current literary theories and practices which developed from contemporary philosophy. Structuralism, associated with Ferdinand de Saussure and Claude Levi-Strauss, with a seemingly scientific view of language and culture posited a systemic "center" that organized and sustained an entire…

  16. Sartre: A Collection of Critical Essays. Twentieth Century Views Series.

    ERIC Educational Resources Information Center

    Kern, Edith, Ed.

    One of a series of works aimed at presenting contemporary critical opinion on major authors, this collection includes essays by Edith Kern, Claude-Edmonde Magny, Henri Peyre, Kenneth Douglas, Edmund Wilson, Theophil Spoerri, Jacques Guicharnaud, Eric Bentley, Robert Champigny, Oreste F. Pucciani, Frederic Jameson, Rene Girard, Guido…

  17. Comparison between reverse Brayton and Kapitza based LNG boil-off gas reliquefaction system using exergy analysis

    NASA Astrophysics Data System (ADS)

    Kochunni, Sarun Kumar; Chowdhury, Kanchan

    2017-02-01

    LNG boil-off gas (BOG) reliquefaction systems in LNG carrier ships uses refrigeration devices which are based on reverse Brayton, Claude, Kapitza (modified Claude) or Cascade cycles. Some of these refrigeration devices use nitrogen as the refrigerants and hence nitrogen storage vessels or nitrogen generators needs to be installed in LNG carrier ships which consume space and add weight to the carrier. In the present work, a new configuration based on Kapitza liquefaction cycle which uses BOG itself as working fluid is proposed and has been compared with Reverse Brayton Cycle (RBC) on sizes of heat exchangers and compressor operating parameters. Exergy analysis is done after simulating at steady state with Aspen Hysys 8.6® and the comparison between RBC and Kapitza may help designers to choose reliquefaction system with appropriate process parameters and sizes of equipment. With comparable exergetic efficiency as that of an RBC, a Kaptiza system needs only BOG compressor without any need of nitrogen gas.

  18. Modeling of SOC-700 Hyperspectral Imagery with the CAMEO-SIM Code

    DTIC Science & Technology

    2007-10-26

    Yannick, 2001, “SOC-700 and HS-Analysis 2 User’s Manual”, Surface Optics, San Diego [2] Cohen, Michael F. and Wallace, John R., 1993, “ Radiosity ...and Realistic Image Synthesis”, Academic Press, San Francisco [3] Sillion, Francois X. and Puech, Claude, 1994, “ Radiosity and Global Illumination

  19. 75 FR 43809 - Airworthiness Directives; Piper Aircraft, Inc. PA-28, PA-32, PA-34, and PA-44 Series Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-27

    ... Aircraft Owners and Pilots Association (AOPA), Barry Rogers, Bruce Chien, and Harry Cook commented that... Absorbed by Piper John Witosky, Thomas McIntosh, Claude Dalrymple, Jr., M. Hefter, and George Haffey..., Barry Rogers, Matt Gunsch, Thomas McIntosh, and four other commenters stated that the FAA needs to...

  20. Levi-Strauss's "Bricolage" and Theorizing Teachers' Work.

    ERIC Educational Resources Information Center

    Hatton, Elizabeth

    1989-01-01

    A teacher's work is compared to Claude Levi-Strauss's concept of "bricolage." A "bricoleur" is a professional do-it-yourself person, falling somewhere between an odd-job person and a craftsperson. The concept helps to explain pedagogical inadequacy by linking inherent limiting features of teachers' work and some causal…

  1. Structural Reform in Higher Education Collective Bargaining. Proceedings of the Annual Conference of the National Center for the Study of Collective Bargaining in Higher Education and the Professions (12th, New York, New York, April 1984).

    ERIC Educational Resources Information Center

    Douglas, Joel M., Ed.

    Structural reform in higher education collective bargaining is examined in these conference proceedings, along with recent state bargaining legislation, and legal, union, and management views concerning sex discrimination in higher education. The 19 article topics and authors include: the problem of reshaping the fringe package (Claude Campbell);…

  2. Alcohol and the Elderly. Hearing before the Subcommittee on Health and Long-Term Care of the Select Committee on Aging. House of Representatives, Ninety-Eighth Congress, First Session (June 10, 1983, Astoria, N.Y.).

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. House Select Committee on Aging.

    The proceedings of the Congressional hearing on alcohol and the elderly are presented. Following introductory statements by the committee chairman, Senator Claude Pepper, and Representatives Mario Biaggi and Geraldine Ferraro, the briefing paper, "Crisis in Health Care Part 2: Alcoholism," prepared by the subcommittee staff is presented.…

  3. Stereotype Threat, Identification with Academics, and Withdrawal from School: Why the Most Successful Students of Colour Might Be Most Likely to Withdraw

    ERIC Educational Resources Information Center

    Osborne, Jason W.; Walker, Christopher

    2006-01-01

    Claude Steeles' stereotype threat hypothesis posits that when there are negative stereotypes about the intellectual capacity of certain (stigmatised) groups, members of that group suffer aversive consequences; group members who are most strongly identified with the stigmatised domain in question (e.g., intellectual or academic ability) are those…

  4. Beyond the Laboratory: Evaluating the Survey Evidence for the Disidentification Explanation of Black-White Differences in Achievement.

    ERIC Educational Resources Information Center

    Morgan, Stephen L.; Mehta, Jal D.

    2004-01-01

    The black-white gap in achievement, as measured by performance on standardized tests, has received considerable attention from researchers in the past five years. Claude Steele's stereotype threat and disidentification mechanism is perhaps the most heralded of the new explanations for residual racial differences that persist after adjustments for…

  5. Test Scores and Stereotypes.

    ERIC Educational Resources Information Center

    Gose, Ben

    1995-01-01

    A psychologist's research suggests that black and female students may have lower standardized test scores and academic achievement because they have accepted stereotypes concerning their ability. Critics feel the researcher, Claude M. Steele, may be overlooking other factors. Steele has developed a program a Stanford University (California) to…

  6. Actes des Journees de linguistique (Proceedings of the Linguistics Conference) (13th, Quebec, Canada, March 25-26, 1999).

    ERIC Educational Resources Information Center

    Kavanagh, Eric, Ed.

    Papers on language research in this volume include the following: Pour une comparaison des voyelles nasals du Quebec et du Haut-Jura: observations, methodologie et outils infomatiques (A Comparison of Quebec and Haut-Jura's Nasal Vowels: Observations, Methodologies, and Instrumentation) (Vincent Arnaud and Claude Paradis); Le negociation du sens…

  7. Observatoire de Lyon

    NASA Astrophysics Data System (ADS)

    Murdin, P.

    2000-11-01

    The Observatoire de Lyon is a laboratory of Université Claude Bernard Lyon1, under the authority of the INSTITUT NATIONAL DES SCIENCES DE L'UNIVERS. It constitutes the Centre de Recherche astrophysique de Lyon together with the astrophysics group of the École Normale Supérieure de Lyon....

  8. Kindergarten Monets

    ERIC Educational Resources Information Center

    Dionne, Suzanne

    2012-01-01

    Integrating art with literature and science enhances students' learning and retention. Whenever possible, the introduction of the author's art lessons include a relevant artist, such as Claude Monet. In this article, kindergartners paint a pond and learn how to make water lilies using colored tissue-paper squares. (Contains 4 resources.)

  9. Evolution of an Educator: Lessons Learned and Challenges Ahead

    ERIC Educational Resources Information Center

    Modell, Harold I.

    2004-01-01

    In selecting a Claude Bernard Distinguished Lecturer, the Teaching Section looks for an individual who has made major contributions to physiology education. Dr. Harold Modell has certainly earned this honor. Harold has an undergraduate degree from the University of Minnesota, a Masters in biomedical engineering from Iowa State, and, continuing the…

  10. Repetition Makes an Impression.

    ERIC Educational Resources Information Center

    Slemmer, Paula M.

    1999-01-01

    Describes two art projects, one for second-grade students and the other for third-grade students, inspired by the artwork of Claude Monet. The second-graders created leaf prints to frame the Impressionist autumn trees they painted, while the third-grade lesson centered around the videotape "Linnea in Monet's Garden." (CMK)

  11. 33 CFR 117.458 - Inner Harbor Navigation Canal, New Orleans.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Inner Harbor Navigation Canal, New Orleans. 117.458 Section 117.458 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF... Harbor Navigation Canal, New Orleans. (a) The draws of the SR 46 (St. Claude Avenue) bridge, mile 0.5...

  12. Symbolic Non-Violence in the Work of Teachers in Alternative Education Settings

    ERIC Educational Resources Information Center

    Waters, Richard

    2017-01-01

    Patterns in analysis of research data on alternative education practices as well as on student and teacher experience in mainstream settings seem to support Pierre Bourdieu and Jean Claude Passeron's theory of symbolic violence. Data from teachers and students suggest that students from low socio-economic backgrounds often disengage from education…

  13. Workers' Attitudes to Technical Change: An Integrated Survey of Research. Industrial Relations Aspects of Manpower Policy 2.

    ERIC Educational Resources Information Center

    Touraine, Alain; And Others

    Methods for encouraging positive worker attitude and behavior toward change were examined to provide a basis for re-evaluation of current policies and programs relating to introduction of technological changes. The literature reviewed is presented in sections of: (1) "The Worker and the Occupational System," by Claude Durand, (2)…

  14. Abuses in Guardianship of the Elderly and Infirm: A National Disgrace. A Briefing by the Chairman of the Subcommittee on Health and Long-Term Care of the Select Committee on Aging. House of Representatives, One Hundredth Congress, First Session (September 25, 1987).

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. House Select Committee on Aging.

    This document presents a briefing by Representative Claude Pepper on the abuses in guardianship of the elderly and infirm, and testimony from witnesses at the Congressional hearing called to examine the issue of guardianship abuse. The opening statement of Representative Pepper and a prepared statement of Representative Helen Delich Bentley are…

  15. Elder Abuse. Hearing before the Subcommittee on Health and Long-Term Care of the Select Committee on Aging. House of Representatives, Ninety-Ninth Congress, First Session.

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. House Select Committee on Aging.

    This document contains testimony and prepared statements from a Congressional hearing called to examine the issue of elder abuse. Chairman Claude Pepper's opening statement discusses the horror of elder abuse and calls for federal legislation, similar to the child abuse legislation, for combating elder abuse. Elder abuse is defined as physical…

  16. Unprovable Security of Two-Message Zero Knowledge

    DTIC Science & Technology

    2012-12-19

    functions on NP-hardness. In STOC ’06, pages 701–710, 2006. 10 [BCC88] Gilles Brassard, David Chaum , and Claude Crépeau. Minimum disclosure proofs...security of several primitives (e.g., Schnorr’s identification scheme, commitment schemes secure under weak notions of selective open- ing, Chaum blind

  17. Identification with Academics, Academic Outcomes, and Withdrawal from School in High School Students: Is There a Racial Paradox?

    ERIC Educational Resources Information Center

    Osborne, Jason W.; Walker, Christopher; Rausch, John L.

    Identification with academics, or the extent to which academic is central to self-concept, has been linked to academic outcomes conceptually and empirically, at least in samples of white college students. However, Claude Steele's Stereotype Threat Hypothesis (1997) proposes something of a racial paradox, by which the most identified students of…

  18. Linking Stereotype Threat and Anxiety

    ERIC Educational Resources Information Center

    Osborne, Jason W.

    2007-01-01

    Claude Steele's stereotype threat hypothesis has attracted significant attention in recent years. This study tested one of the main tenets of his theory--that stereotype threat serves to increase individual anxiety levels, thus hurting performance--using real-time measures of physiological arousal. Subjects were randomly assigned to either high or…

  19. Coding and Quantization in Communications and Microeconomics

    ERIC Educational Resources Information Center

    Xu, Yun

    2013-01-01

    Since information theory was developed by Claude E. Shannon, in addition to its primary role in communications and networking, it has broadened to find applications in many other areas of science and technology, such as microeconomics, statistics, and neuroscience. This thesis investigates the application of information theoretic viewpoints to two…

  20. Panning for Gold: Utility of the World Wide Web for Metadata and Authority Control in Special Collections.

    ERIC Educational Resources Information Center

    Ellero, Nadine P.

    2002-01-01

    Describes the use of the World Wide Web as a name authority resource and tool for special collections' analytic-level cataloging, based on experiences at The Claude Moore Health Sciences Library. Highlights include primary documents and metadata; authority control and the Web as authority source information; and future possibilities. (Author/LRW)

  1. Long-Term Care: Need for a National Policy. Hearing before the Subcommittee on Health and Long-Term Care of the Select Committee on Aging. House of Representatives, Ninety-Eighth Congress, First Session (December 15, 1983, San Francisco, California).

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. House Select Committee on Aging.

    This document contains transcripts of witness testimony and prepared statements from the Congressional hearing called to review the need for a national health care policy for long-term care. Opening statements are presented from committee chairman Claude Pepper and from Representatives Sala Burton and Barbara Boxer. Testmonies are presented from…

  2. Resonant and Nonresonant Nonlinear Optical Spectroscopy of CDSE Quantum Dots for Nonlinear Photonic Applications

    DTIC Science & Technology

    2006-11-01

    Temple D., Yoo K. P., Kim S. Y., Mott A., Namkung M., and Jung S. S., 2003: Large and pure refractive nonlinearity of nanostructure silica ... aerogel , Appl. Phys. Lett., 82(25), 4444-4446. [18] Sun W., Patton T., Stultz L., andClaude J. P., 2003: Resonant third-order nonlinearities of tetrakis

  3. A-Train Data Depot (ATDD)

    NASA Technical Reports Server (NTRS)

    Smith, Peter M.; Kempler, Steven; Leptoukh, Gregory; Savtchenko, Andrey; Kummerer, Robert; Gopolan, Arun

    2008-01-01

    ATDD is a web based tool which provides collocated data and display products for a number of A-train instruments Cloudsat, Calipso, OMI, AIRS, MODIS, MLS, POLDER-3, and ECWMF model data. Products provided include Clouds, Aerosols, Water Vapor, Temperatures and trace gases. All input data is online and in HDF4, HDF5 format. Display products include curtain images, horizontal strips, line plot overlays, and GE kmz files. Sample products are shown for two type of events. Hurricane event, Norbert, Oct 8, 2008 and a dust storm event over the Arabian Sea, Nov 13-14, 2008.

  4. STS-46 TCDT Slideware Training and Photo Session

    NASA Technical Reports Server (NTRS)

    1992-01-01

    The crew of STS-46, Commander Loren J. Shriver, Pilot Andrew M. Allen, Payload Specialist Franco Malerba, Mission Specialists Jeffrey A. Hoffman, Franklin R. Chang-Diaz, Claude Nicollier, and Marsha S. Ivins are seen introducing themselves and discussing the mission during a photo session. The crew then answers questions from the press.

  5. The XIIIth International Physiological Congress in Boston in 1929: American Physiology Comes of Age

    ERIC Educational Resources Information Center

    Rall, Jack A.

    2016-01-01

    In the 19th century, the concept of experimental physiology originated in France with Claude Bernard, evolved in Germany stimulated by the teaching of Carl Ludwig, and later spread to Britain and then to the United States. The goal was to develop a physicochemical understanding of physiological phenomena. The first International Physiological…

  6. 76 FR 45614 - Notice of Availability of the Final Environmental Impact Statement for the Proposed Over the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-29

    ... hours. The FIRS is available 24 hours a day, 7 days a week, to leave a message or question with the above individual. You will receive a reply during normal business hours. SUPPLEMENTARY INFORMATION: The OTR Corporation, formed by the artists Christo and Jeanne-Claude, proposes to install a work of art...

  7. Integrate the Arts. Monet's Garden Pops Up!

    ERIC Educational Resources Information Center

    Parks, Mary

    1996-01-01

    This article outlines the steps in an art activity on the elements of landscapes and touches on the topic of perspective. In the activity students create three-dimensional secret gardens of their own out of construction paper. The activity is based on Claude Monet's painting and his garden in Giverny (Normandy, France). (SM)

  8. Show Me the Monet!...and Other Artists.

    ERIC Educational Resources Information Center

    Roman, Michele

    1999-01-01

    Describes a project designed to advertise art history where eighth-grade students painted the classroom door windows throughout their school recreating famous classic paintings from various artists, such as Claude Monet or Vincent van Gogh. Explains that the students learned about different artistic styles and exhibited a great deal of pride in…

  9. Retreat to Eden: Time and the Cosmos in Monet's Images of Giverny.

    ERIC Educational Resources Information Center

    Call, Michael

    1997-01-01

    Attempts to explain Claude Monet's obsession with water lilies in the last 25 years of his life through an interdisciplinary approach combining ideas from the history of landscape design, social history, and anthropology. Offers Monet's gardens at Giverny (France), his series paintings, and the railroad as some possible influences on his painting.…

  10. The Attempted Dismantling of the Medicare Home Care Benefit. A Report by the Chairman of the Subcommittee on Health and Long-Term Care of the Select Committee on Aging. House of Representatives, Ninety-Ninth Congress, Second Session.

    ERIC Educational Resources Information Center

    Pepper, Claude

    This document presents Congressman Claude Pepper's report on the Medicare Home Care Benefit. Section I traces the history of home health care in the United States. Section II offers statistics and general background information about older Americans and Medicare. The beginning of the Medicare home care benefit and its present operation are…

  11. APS at 125: A Look Back at the Founding of the American Physiological Society

    ERIC Educational Resources Information Center

    Ryan, Kathy L.

    2013-01-01

    Early efforts in physiological research in the United States were produced by lone investigators working in laboratories funded by their own medical practices. In Europe, however, Claude Bernard and Carl Ludwig produced a new model of scientific research laboratories funded by the state that sought to develop the pursuit of biomedical research as…

  12. Modern Impressions

    ERIC Educational Resources Information Center

    Simkus, Joyce

    2010-01-01

    Claude Monet and the Impressionists were the forward thinkers and painters of their time. They used quick brushstrokes and a rapid pace to capture lively outdoor scenes. Inspired by the colors and shadows revealed by sunlight, the Impressionists typically worked outside, without many preliminary sketches or drafts. This was in direct contrast to…

  13. Monet's Water Lilies

    ERIC Educational Resources Information Center

    Maroni, Michelle

    2006-01-01

    Students love the colors of Monet prints. The sunny yellows, misty blues, soft lavenders, and outrageous oranges. Using this as inspiration, Michelle Maroni wanted her students to discover new painting techniques and ways of planning a composition with more spontaneity. In this article, she describes how she introduced Claude Monet to her students…

  14. It's a Wrap! A Study of Installations.

    ERIC Educational Resources Information Center

    Buck, Susan

    2002-01-01

    Describes an art project for junior and senior high school students called the wrapped chair project where students wrapped chairs using torn sheets in the style of artists, Christo Javacheff and Jeanne-Claude de-Guillebon. Explains that students created thumbnail sketches and drew their finished drawing in either charcoal or chalk. (CMK)

  15. STS-46 ESA MS Nicollier in life raft during water egress training at JSC WETF

    NASA Technical Reports Server (NTRS)

    1992-01-01

    STS-46 Atlantis, Orbiter Vehicle (OV) 104, European Space Agency (ESA) Mission Specialist (MS) Claude Nicollier, wearing launch and entry suit (LES) and launch and entry helmet (LEH), floats in a one-person life raft during a launch emergency egress (bailout) simulation conducted in JSC's Weightless Environment Training Facility (WETF) Bldg 29 pool.

  16. Safety and Efficacy of Over-the-Counter Drug Use by the Elderly. Hearing before the Subcommittee on Health and Long-Term Care of the Select Committee on Aging. House of Representatives, Ninety-Eighth Congress, First Session.

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. House Select Committee on Aging.

    This document contains the prepared statements and panel testimony from the Congressional hearing on over-the-counter (OTC) drug use by the elderly. Opening statements are given by Representatives Claude Pepper (chairman), Ralph Regula, Mary Rose Oakar, Michael Bilirakis, Tom Lantos, and Hal Daub. Topics which are covered include the incidence and…

  17. Monet Flowers: How My Summer Trip Inspired a Garden of Art...

    ERIC Educational Resources Information Center

    Dunay, Cecelia M.

    1998-01-01

    Describes a lesson plan designed for first- through fifth-grade students in which they made their own impressionist-style artworks. Explains that the lesson was introduced with a discussion on Claude Monet, his many art prints, and the impressionist genre. Explores the differences between things of nature and man-made objects. Notes materials and…

  18. Biological Basis for Chemoprevention of Ovarian Cancer. Addendum

    DTIC Science & Technology

    2007-10-01

    Campbell I, Chang-Claude J, Peel D, Anton-Culver H, Berchuck A, Schildkraut J, Whittemore A, McGuire V, DiCioccio RA, Duffy D, Chenevix-Trench G...promotor polymorphism and ovarian cancer risk. Int J Cancer 2000;86:436–9. 23. Menin C, Banna GL, De Salvo G, et al. Lack of association between

  19. Biological Basis for Chemoprevention of Ovarian Cancer

    DTIC Science & Technology

    2006-10-01

    2005;16:955-63. 11) Kelemen L, James M, Spurdle A, Campbell I, Chang-Claude J, Peel D, Anton-Culver H, Berchuck A, Schildkraut J, Whittemore A...X., Abbazadegan, M., et al. CYP17 promotor polymorphism and ovarian cancer risk. Intl J Cancer. 2000; 86: 436-9. 23.Menin, C., Banna , G. L., De

  20. Videotape Recording of Narcotic Addicts in Group Therapy: The Analysis of Communicational and Interactive Behavior.

    ERIC Educational Resources Information Center

    Soloway, Irv

    An approach to the study of drug sub-culture groups and a model for predictive research in the identification and isolation of heroin addicts are developed in this thesis. The basic methodologies employed are the linguistic methods of Kenneth Pike and Claude Levi-Strauss for use in the analysis of social phenomena. Communicative mechanisms by…

  1. Monet's Reflections

    ERIC Educational Resources Information Center

    Petrovich-Cheney, Laura

    2007-01-01

    From 1899 until his death in 1926, Claude Monet painted a series of watercolor landscapes of his water lily garden and Japanese bridge in Giverny, France. Monet eventually abandoned the banks entirely as subject matter and concentrated solely on the water. These paintings, particularly "The Water Lilies," show a surface in which the shimmering…

  2. 365 days UNDER ANTARCTIC ICE - a Djamel Tahi film, produced by Terra Incognita in coproduction with CNRS

    NASA Astrophysics Data System (ADS)

    Schlich, R.; Lorius, C.

    2009-04-01

    The 1st July 1957 marks the beginning of the International Geophysical Year. The scientific world decided to explore the Antarctic. Twelve nations would join efforts to initiate a vast research programme aimed to penetrate the mysteries of the white continent. Three Frenchmen, Jacques Dubois, a meteorologist, Roland Schlich, a geophysicist, and Claude Lorius a glaciologist, occupied the Charcot Station built near the South magnetic pole and located 320 km from the coast, during a whole year without any possibility of relief. They wintered from January 1957 to January 1958 in an aluminium hut only 24 m2 in size, buried under the ice. Today, Roland Schlich of the School and Observatory of Earth Sciences, Strasbourg and Claude Lorius of the Laboratory of Glaciology and Geophysics of the Environment, Grenoble, are the last witnesses of this wintering and they remember … The film traces this human and scientific adventure, thanks to their evidence and unpublished documents, filmed 50 years ago. The English version of the film is sponsored by the European Geosciences Union (EGU) and the Scientific Committee on Antarctic Research (SCAR).

  3. Physiological regulation through learnt control of appetites by contingencies among signals from external and internal environments.

    PubMed

    Booth, David A

    2008-11-01

    As reviewed by [Cooper, S. J. (2008). From Claude Bernard to Walter Cannon: emergence of the concept of homeostasis. Appetite 51, 419-27.] Claude Bernard's idea of stabilisation of bodily states, as realised in Walter B. Cannon's conception of homeostasis, took mathematical form during the 1940s in the principle that externally originating disturbance of a physiological parameter can feed an informative signal around the brain to trigger counteractive processes--a corrective mechanism known as negative feedback, in practice reliant on feedforward. Three decades later, enough was known of the physiology and psychology of eating and drinking for calculations to show how experimentally demonstrated mechanisms of feedforward that had been learnt from negative feedback combine to regulate exchanges of water and energy between the body and the surroundings. Subsequent systemic physiology, molecular neuroscience and experimental psychology, however, have been traduced by a misconception that learnt controls of intake are 'non-homeostatic', the myth of biological 'set points' and an historic failure to address evidence for the ingestion-adapting information-processing mechanisms on which an operationally integrative theory of eating and drinking relies.

  4. Judge Rules Plagiarism-Detection Tool Falls under "Fair Use"

    ERIC Educational Resources Information Center

    Young, Jeffrey R.

    2008-01-01

    Judge Claude M. Hilton, of the U.S. District Court in Alexandria, Virginia, in March found that scanning the student papers for the purpose of detecting plagiarism is a "highly transformative" use that falls under the fair-use provision of copyright law. He ruled that the company "makes no use of any work's particular expressive or creative…

  5. Native Sons: A Critical Study of Twentieth-Century Negro American Authors.

    ERIC Educational Resources Information Center

    Margolies, Edward

    This analysis of 20th-century Negro literature contains chapters discussing 16 authors: (1) "The First Forty Years: 1900-1940," including W. E. B. DuBois, Charles W. Chesnutt, James W. Johnson, Paul L. Dunbar, Langston Hughes, Jean Toomer, Claude McKay, and Countee Cullen; (2) "Migration: William Attaway and 'Blood on the Forge'"; (3) "Richard…

  6. A Course Connecting Astronomy to Art, History, and Literature

    ERIC Educational Resources Information Center

    Olson, Don

    2015-01-01

    For the past 20 years the author has taught an Honors College course combining astronomy and the humanities. The purpose of this note is to give examples of methods that can be adapted to classroom use for topics including night sky paintings by Vincent van Gogh, Edvard Munch, and Claude Monet, historical events influenced by astronomical factors,…

  7. An Evolution in Student-Centered Teaching

    ERIC Educational Resources Information Center

    Goodman, Barbara E.

    2016-01-01

    The American Physiological Society (APS) Teaching Section annually honors an educator through its Claude Bernard Distinguished Lecture at the Experimental Biology meeting. Since I knew about my selection for almost a year, I had a long time to think about what I wanted to say and how I wanted to say it. The theme of my presentation was…

  8. Travaux Neuchatelois de linguistique (Neuchatel Working Papers in Linguistics).

    ERIC Educational Resources Information Center

    Neuchatel Univ. (Switzerland). Inst. de Linguistique.

    This collection of working papers in linguistics includes four works. "Autour de la racine indo-europeenne 'pet-' ('voler') (pour servir a l'histoire des faits latins)" ("Concerning the Indo-European Root 'Pet-' ('To Fly') (To Serve as an Example of Latin Facts)" by Claude Sandoz looks at the Latin manifestations of the root and illustrates the…

  9. Ability Is Ageless. Hearing before the Subcommittee on Health and Long-Term Care of the Select Committee on Aging. House of Representatives, Ninety-Ninth Congress, Second Session.

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. House Select Committee on Aging.

    This document presents the text of a hearing on the relationship of ability to age, in reference to removing age caps so that age will be irrelevent to getting and keeping a job. Statements by Representatives Ron Wyden, Claude Pepper, Ralph Regula, Bill Schuette, Jim Lightfoot, Ike Skelton, George Wortley, and Don Bonker are included. Testimony by…

  10. Long-Term Care Insurance: Coverage Varies Widely in a Developing Market. Report to the Chairman, Subcommittee on Health and Long-Term Care, Select Committeee on Aging, House of Representatives.

    ERIC Educational Resources Information Center

    General Accounting Office, Washington, DC. Div. of Human Resources.

    In response to a request by Congressman Claude Pepper, the General Accounting Office (GAO) conducted a study to examine the private long-term care insurance market. The GAO analyzed the premiums, benefits, and limitations of 33 policies offered by 25 insurers in 1986. The GAO assessed the potential for abuse in this market by surveying state…

  11. Culture and Identity: Critical Considerations for Successful State-building Endeavors

    DTIC Science & Technology

    2010-05-21

    cultures. The literature consulted was largely based on anthropological and political science research both of which also included references to...ambiguity. 79 For the purposes of this research and analysis, the definitions of culture offered by the political science and anthropological ...is both a metaquestion, and 80 Claude Lévi-Strauss, “Social Structure” in Anthropology Today

  12. 76 FR 11561 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-02

    ....A., Cali, Colombia; c/o INVERSIONES CIFUENTES Y CIA. S. EN C., Medellin, Colombia; c/o PARQUES...., Mexico City, Distrito Federal, Mexico; c/o INVERSIONES CIFUENTES Y CIA. S. EN C., Medellin, Colombia; c/o..., Colombia; c/o INVERSIONES CIFUENTES Y CIA. S. EN C., Medellin, Colombia; c/o LE CLAUDE, S.A. DE C.V...

  13. The 2014 Claude Bernard Distinguished Lecture: the social contract of learning.

    PubMed

    Carroll, Robert G

    2015-03-01

    The shift to competency-based education expands the role of the teacher from that of a provider of information and into a shaper of knowledge, skills, and attitudes. These roles are facilitated by establishing a social contract between the instructor and learner, a contract that clearly defines the rights and duties of each. Adopting greater responsibility for the development of competencies in our learners allows faculty members to truly have an impact by shaping the behaviors of learners. Copyright © 2015 The American Physiological Society.

  14. The 2014 Claude Bernard Distinguished Lecture: The Social Contract of Learning

    ERIC Educational Resources Information Center

    Carroll, Robert G.

    2015-01-01

    The shift to competency-based education expands the role of the teacher from that of a provider of information and into a shaper of knowledge, skills, and attitudes. These roles are facilitated by establishing a social contract between the instructor and learner, a contract that clearly defines the rights and duties of each. Adopting greater…

  15. Latency-Information Theory: The Mathematical-Physical Theory of Communication-Observation

    DTIC Science & Technology

    2010-01-01

    Werner Heisenberg of quantum mechanics; 3) the source-entropy and channel-capacity lossless performance bounds of Claude Shannon that guide...through noisy intel-space channels, and where the physical time-dislocations of intel-space exhibit a passing of time Heisenberg information...life-space sensor, and where the physical time- dislocations of life-space exhibit a passing of time Heisenberg information-uncertainty; and 4

  16. 33 CFR 117.458 - Inner Harbor Navigation Canal, New Orleans.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Harbor Navigation Canal, New Orleans. (a) The draws of the SR 46 (St. Claude Avenue) bridge, mile 0.5 (GIWW mile 6.2 East of Harvey Lock), the SR 39 (Judge Seeber/Claiborne Avenue) bridge, mile 0.9 (GIWW mile 6.7 East of Harvey Lock), and the Florida Avenue bridge, mile 1.7 (GIWW mile 7.5 East of Harvey...

  17. 33 CFR 117.458 - Inner Harbor Navigation Canal, New Orleans.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Harbor Navigation Canal, New Orleans. (a) The draws of the SR 46 (St. Claude Avenue) bridge, mile 0.5 (GIWW mile 6.2 East of Harvey Lock), the SR 39 (Judge Seeber/Claiborne Avenue) bridge, mile 0.9 (GIWW mile 6.7 East of Harvey Lock), and the Florida Avenue bridge, mile 1.7 (GIWW mile 7.5 East of Harvey...

  18. 33 CFR 117.458 - Inner Harbor Navigation Canal, New Orleans.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Harbor Navigation Canal, New Orleans. (a) The draws of the SR 46 (St. Claude Avenue) bridge, mile 0.5 (GIWW mile 6.2 East of Harvey Lock), the SR 39 (Judge Seeber/Claiborne Avenue) bridge, mile 0.9 (GIWW mile 6.7 East of Harvey Lock), and the Florida Avenue bridge, mile 1.7 (GIWW mile 7.5 East of Harvey...

  19. [The sense of the senseless, psychoanalytic aspects of delusion in psychosis].

    PubMed

    Chaperot, Christophe

    2011-01-01

    The psychoanalytic approach to delusion in psychosis leads us to examine the function of a "furrow". It is necessary to remain in the furrow in order not to become delusional. References to Sigmund Freud, Jacques Lacan, Mélanie Klein and Jean-Claude Maleval enlighten us as to the origin and the function of delusion as an attempt to give meaning.

  20. European astronaut training in Houston.

    PubMed

    Chiarenza, O

    1993-11-01

    Three European astronauts are currently training as Space Shuttle Mission Specialists at NASA's Johnson Space Center in Houston. Two of the astronauts, Maurizio Cheli and Jean-Francois Clervoy, recently became members of NASA's 'astronaut pool' and have entered the Advanced Training phase. The third one, Claude Nicollier, is now preparing for the mission to service the Hubble Space Telescope in December.

  1. Painting a Data-Rich Picture

    ERIC Educational Resources Information Center

    Earl, Lorna; Katz, Steven

    2005-01-01

    Using data for school reform is like painting a series of pictures--pictures that are subtle and capture the nuances of the subject. This is a far cry from drawing stick figures or paint-by-numbers. Imagine the experiences of the French painter Claude Monet as he wandered through his garden at Giverny at different times of the day and year,…

  2. STS-46 crewmembers during water egress training in JSC's WETF Bldg 29

    NASA Technical Reports Server (NTRS)

    1992-01-01

    STS-46 Atlantis, Orbiter Vehicle (OV) 104, European Space Agency (ESA) Mission Specialist (MS) Claude Nicollier (left) and backup Italian Payload Specialist Umberto Guidoni, seated at the pool's side, relax before participating in a launch emergency egress (bailout) simulation in JSC's Weightless Environment Training Facility (WETF) Bldg 29. The two participants are wearing launch and entry suits (LESs) during the pretest briefing.

  3. MIT Lincoln Laboratory Annual Report 2007: Technology in Support of National Security

    DTIC Science & Technology

    2007-01-01

    technical innovation and scientific discoveries. MISSION: TechnoLogy In SupporT of naTIonaL SecurITy 2007 Dr. Claude R. Canizares Vice president for...problems. The Lincoln Laboratory New Technology Initiatives Program is one of several internal technology innovation mechanisms. Technologies emerging...externships. LIFT2, an innovative professional learning program for science, technology , and math teachers, serves Massachusetts metro south/west region

  4. The Gates, 1979-2005

    ERIC Educational Resources Information Center

    School Arts: The Art Education Magazine for Teachers, 2005

    2005-01-01

    One art critic called it pure Despite the mixed reviews of Christo and Jeanne-Claude's temporary art installation in New York's Central Park, the public reaction to The Gates was largely positive.The Gates consisted of 7,500 orange PVC frames straddling the park's walkways that varied in widths from 5 1/2 feet to 18 feet. Eight-foot-long ripstop…

  5. Astronaut Jeffrey Hoffman on RMS during third of five HST EVAs

    NASA Image and Video Library

    1993-12-07

    STS061-105-026 (7 Dec. 1993) --- Astronaut Jeffrey A. Hoffman signals directions to European Space Agency (ESA) astronaut Claude Nicollier, as the latter controls the Remote Manipulator System (RMS) arm during the third of five Extravehicular Activities (EVA) on the Hubble Space Telescope (HST) servicing mission. Astronauts Hoffman and F. Story Musgrave earlier changed out the Wide Field\\Planetary Camera (WF\\PC).

  6. Where Are They Now: Emily Burnett Aims Even Higher Thanks to Internship Experience | Poster

    Cancer.gov

    Emily Burnett, a five-time intern with NCI at Frederick’s Occupational Health Services (OHS), says the Werner H. Kirsten Student Intern Program program helped shape her current career trajectory. When she began her first OHS internship in 2015, her heart was set on becoming a nurse. However, after working with mentor Sarah Hooper and secondary mentor Patricia Claude, she

  7. Identification of new phytoconstituents and antimicrobial activity in stem bark of Mangifera indica (L.).

    PubMed

    Singh, Ruchi; Singh, S K; Maharia, R S; Garg, A N

    2015-02-01

    Mangifera indica, commonly called mango or amra belonging to a family of Anacardiaceae, is an important medicinal plant widely used in a variety of Ayurvedic preparations. Extract of its bark, leaves, flowers and kernels are being extensively used for curing various chronic diseases. Mango wood is used in yagya as base fire through which medicated smoke is generated. Three new compounds have been isolated from methanolic and hexane extracts of stem bark: 1,2-benzenedicarboxylic acid, mono(2-ethylhexyl)ester and 9,12-tetradecadiene-1-ol-acetate from the hexane extract and 3-chloro-N-(2-phenylethyl) propanamide from the methanolic extract. These were first separated by thin layer chromatography and later in a silica gel column and identified by characteristic infrared bands corresponding to respective functional groups. The compounds were further confirmed on the basis of GC-MS fragmentation pattern after comparing the data with NIST mass spectral database. All three compounds exhibited antimicrobial activity due to triterpenoids and flavonoids. Elemental analyses by INAA show it to be enriched in essential nutrient elements such as Ca, Fe, K, Mn and Zn which all play an important role in enzymatic processes. Copyright © 2014 Elsevier B.V. All rights reserved.

  8. Potential Implications of Changes in ChalleNGe Admission Criteria: A Literature Review

    DTIC Science & Technology

    2015-04-01

    experiment, Steele, Spencer , and Aronson (2002) administered a 25- minute section of the math GRE [58]. Some women were given a “stereotype-threat...final.pdf. [31] Uguroglu, Margaret E., and Herbert J. Walberg. 1979. “Motivation and Achievement: A Quantitative Synthesis.” American Educational...Analysis of Educational Productivity.” Education Economics 7 (3): 199-208. [58] Steele, Claude M., Steven J. Spencer , and Joshua Aronson. 2002

  9. [The ethics of animal experimentation].

    PubMed

    Goffi, Jean-Yves

    2013-01-01

    The paper starts with a short definition of animal experimentation, then three main approaches to the practice are considered: unconditional approval (as advocated by Claude Bernard), conditional and restricted approval (as advocated by Peter Singer) and strict prohibition (as advocated by Tom Regan and Gary Francione). It is argued that what is actually approved or condemned in animal experimentation is the value of the scientific enterprise.

  10. A Special Force: Origin and Development of the Jedburgh Project in Support of Operation Overload

    DTIC Science & Technology

    1991-06-07

    final preparations for de ,ployment. It Includes ai study of the recruitment process used to man the force ad the training prngram undertaken to prepare...le Borgne, Prince Michel de Bourbon de Parme, Colonel (Ret.) Robert Cantais, Joseph Carbuccia, Robert Clause, Rene Esteve, Francois Franceschi, Joe... de Francesco, Maurice Geminel, Adrien Grafeville, Colonel (Ret.) Paul Grall, Claude l’Herbette, Xavier Humblet, Lieutenant Colonel (Ret.) Pierre

  11. Thematic Trends in Claude McKay's Selected Poems of "the Harlem Era"

    ERIC Educational Resources Information Center

    Adewumi, Samuel Idowu; Kayode, Moses Bolawale

    2014-01-01

    Black American Literature is a microcosm of the history of the black people's presence on the American continent as it is known today. The literature of the Black Americans cannot be fully separated from the experience of Slavery and Racism which characterized their lives as a community of people whose social, economic and political privileges are…

  12. European Space Agency (ESA) Mission Specialist Nicollier trains in JSC's WETF

    NASA Technical Reports Server (NTRS)

    1987-01-01

    European Space Agency (ESA) Mission Specialist (MS) Claude Nicollier (left) is briefed by Randall S. McDaniel on Space Shuttle extravehicular activity (EVA) tools and equipment prior to donning an extravehicular mobility unit and participating in an underwater EVA simulation in JSC's Weightless Environment Training Facility (WETF) Bldg 29 pool. Nicollier is holding the EMU mini workstation. Other equipment on the table includes EVA tool caddies and EVA crewmember safety tethers.

  13. [Primary intramedullary lymphoma. Case report].

    PubMed

    Peltier, J; Cretu, I; Fichten, A; Toussaint, P; Desenclos, C; Le Gars, D

    2007-11-01

    A 66-year-old female presented primary intramedullary spinal cord lymphoma. This patient was referred for lower limbs weakness, which had developed six weeks earlier and right C5 radiculalgia. Physical examination revealed a medullary syndrome with Claude-Bernard-Horner syndrome. The diagnosis was established after MRI and biopsy (dorsal myelotomy). The patient was given chemotherapy and craniospinal adjuvant radiotherapy (30 Grays). The clinical, radiological and therapeutic features are discussed.

  14. Predicting Suicide Attacks: Integrating Spatial, Temporal, and Social Features of Terrorist Attack Targets

    DTIC Science & Technology

    2013-01-01

    used in health and criminol- ogy to predict outcomes (Browning, Cagney, and Wen, 2003; Samp- son, Morenoff, and Gannon -Rowley, 2002 ). For each...Bernard, H . Russell , and Gery W. Ryan, Analyzing Qualitative Data: Systematic Approaches, Thousand Oaks, Calif.: Sage, 2010. Berrebi, Claude, “Evidence...PERSON a. REPORT unclassified b . ABSTRACT unclassified c. THIS PAGE unclassified Standard Form 298 (Rev. 8-98) Prescribed by ANSI Std Z39-18

  15. Military Review: The Professional Journal of the U.S. Army. Volume 87, Number 4, July-August 2007

    DTIC Science & Technology

    2007-08-01

    Structures, Taji 10. Al Sumood State Company - Foundry, Taji 11. Nassr State Company for Mechanical Ind. - Trailers , Taji 12. Nassr State Company for...Oriental & African Studies (SOAS), london School of economics, london, UK. 35. Comments made to the author at a reception honoring Ambassador Muham...replete with F-bombs, the training events are clarified with allusions to Jean-Claude Van Damme movies , and the central thesis is a recurring conclusion

  16. A Course Connecting Astronomy to Art, History, and Literature

    NASA Astrophysics Data System (ADS)

    Olson, Don

    2015-10-01

    For the past 20 years the author has taught an Honors College course combining astronomy and the humanities. The purpose of this note is to give examples of methods that can be adapted to classroom use for topics including night sky paintings by Vincent van Gogh, Edvard Munch, and Claude Monet, historical events influenced by astronomical factors, and literary references to the sky by authors including Chaucer, Shakespeare, and Walt Whitman.

  17. [The Pluvinet, chemists and grocers, during the french Revolution and the Empire].

    PubMed

    Flahaut, Jean

    2003-01-01

    Between 1750 and 1813, the ancient archives described two Pluvinet: Jean-Claude and Jean-Charles (or Jean-Baptiste-Charles). They were chemists and grocers; they had various activities, with Lavoisier, with Cadet de Gassicourt, at the Council of the City of Paris, etc. But frequent confusions exist between the two first names, and it seems possible that they concern only one man, who changed his first name according to the events.

  18. Shortening The Defense Acquisition Cycle: A Transformation Imperative. Center for Strategic Leadership. November 2002. Issues Paper 13-02

    DTIC Science & Technology

    2002-11-01

    rated. Par tic i pants in these re struc tur ing strat e gies met dif fer ent lev els of suc cess. Monetizers and Evap o ra tors pro vided op por tu ni...have all but elim i nated young work ers in the De fense De part ment’s ac - qui si tion op er a tions.” Mr. Claude M. Bolton Jr., As sis tant Sec re

  19. Comparing Benefit Estimation Techniques: Residential Flood Hazard Reduction Benefits in Roanoke, Virginia

    DTIC Science & Technology

    1998-03-01

    benefit estimation techniques used to monetize the value of flood hazard reduction in the City of Roanoke. Each method was then used to estimate...behavior. This framework justifies interpreting people’s choices to infer and then monetize their preferences. If individuals have well-ordered and...Journal of Agricultural Economics. 68 (1986) 2: 280-290. Soule, Don M. and Claude M. Vaughn, "Flood Protection Benefits as Reflected in Property

  20. Evaluating Navy’s Funded Graduate Education Program. A Return-on-Investment Framework

    DTIC Science & Technology

    2010-01-01

    decisionmaking, and increased retention. Some of this value can be monetized , and costs and benefits to the Navy can be estimated using enhanced...support of LCDR Claude McRoberts, CAPT Karen Emmel, CDR Darin Evenson, CAPT John Coronado, CDR Rob Tortora, CAPT Richard Moyer, LCDR Joseph Scott...step is to monetize the data on education effects by assigning values to the education outcomes predicted in step two and calculating an annual

  1. Investigation of New Subsystem Concepts to Improve the Operational and Hydrodynamic Capabilities of Advanced Amphibian Vehicles

    DTIC Science & Technology

    1980-06-01

    Appendix C), only the following three offered even a slight hope that they might be useful to amphibian developments: the Amphibious Air Track, page A...be associated with future amphibians. Within the past year, the University of Michigan College of Engineering has established the Office for the...Land Interface: Claude A. Blackmon, Beryle G. Stinson Jack K. Stoll AD 881 357 Engineering Design Handbook; Wheeled Amphbians: No author listed AD

  2. Buhne Point Shoreline Erosion Demonstration Project. Volume 4. Appendices H-L.

    DTIC Science & Technology

    1987-08-01

    Districts Corps of Engineers Prepared by Moffatt & Nichol, EngineE -s 250 W. Wardlow Road Long Beach, CA 90807 L-2434.03 August 1987...Francisco District, Corps of Engineers Dave Eyres Federal Highway Administration Ervin Renner Humboldt County Board of Supervisors Tom Smith Federal...James A. Gast Humboldt Bay Harbor District Claude Wong U.S. Army Corps of Engineers , Los Angeles Dean Ray Coastal Commission, Eureka Ervin Renner

  3. OPERATION DOMINIC, FISH BOWL SERIES. Project Officer’s Report. Project 8B. Nuclear Weapon X-Ray Effects as Measured by Passive Instruments

    DTIC Science & Technology

    1985-09-01

    different environ- ments of SF’ and Marshmallow . The data from the Marshmallow gages are reduced and reported in this section; comparison to SF...were adjusted accordingly. Failure of similar gages to fracture in the Marshmallow event made it appear desirable to increase the probability of...and Capt. Claude M. Gillespie; "Reentry Vehicle Composites (U)" POR-1853, Project 834, Operation Nougat, Shot Marshmallow , May 1963; Air Force

  4. Economic contribution of 'artificial upwelling' mariculture to sea-thermal power generation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Roels, O.A.

    1976-07-01

    Deep-sea water has two valuable properties: it is uniformly cold and, compared to surface water, it is rich in nutrients such as nitrate and phosphate which are necessary for plant growth. In tropical and subtropical areas, the temperature difference between the warm surface water and the cold deep water can be used for sea-thermal power generation or other cooling applications such as air-conditioning, ice-making, desalination, and cooling of refineries, power plants, etc. Once the deep water is brought to the surface, utilization of both the cold temperature and the nutrient content is likely to be more advantageous than the usemore » of only one of them. Claude demonstrated the technical feasibility of sea-thermal power generation in Cuba in 1930. The technical feasibility of artificial upwelling mariculture in the St. Croix installation has been demonstrated. Results to date demonstrate that the gross sales value of the potential mariculture yield from a given volume of deep-sea water is many times that of the sales value of the power which can be generated by the Claude process from the same volume of deep water. Utilizing both the nutrient content and the cold temperature of the deep water may therefore make sea-thermal power generation economically feasible.« less

  5. Contribution of physiologists to the identification of the humoral component of immunity in the 19th century

    PubMed Central

    Lahaie, Yves-Marie

    2017-01-01

    ABSTRACT The history of antimicrobial humoral immunity usually focuses on the works of the German school at the end of the 19th century, born in the tradition of chemistry and disinfection. Starting from an old quarrel of priority about serotherapy between Emil von Behring (1854–1917) and the French physiologists Charles Richet (1850–1935) and Jules Héricourt (1850–1938), we first confirm that the latter stated the principle of serotherapy in 1888 and put it into practice before the seminal Behring's article in 1890, observing several adverse effects of this new immunotherapy. We also find that researchers who can be considered heirs of the French school of Physiology founded by Claude Bernard (1813–1878) also investigated the field of humoral immunity in the 1870–1880s. Maurice Raynaud (1834–1881), Auguste Chauveau (1827–1917), and eventually Charles Richet applied the experimental method of Claude Bernard to the young field of microbiology, illustrating a movement called by Jacques Léonard “physiologization of the pasteurism.” However, the contribution of physiologists in this field started before Louis Pasteur, leading to the conclusion that physiologists and chemists synergistically contributed to the birth of bacteriology and immunology. PMID:28557665

  6. Logistical Support of the China Relief Expedition

    DTIC Science & Technology

    1991-06-01

    fruits and jelly .8 Additionally, hard bread (hard tack), rice, beans (preferred over rice by the soldiers), flour, sugar, coffee were issued. These...Sir Claude MacDonald to Captain John Jellicoe, Royal Navy. In the message, MacDonald asked for more troops immediately. Jellicoe relayed the message...to Rear Admiral Edward H. Seymour, Royal Navy, who immediately, in concert with the allies, began to land naval forces to increase the size of the

  7. A Research Design for Archaeological Investigations and Architectural Evaluations within the Proposed Upper Site, New Lock and Connecting Channels, Inner Harbor Navigation Canal, New Orleans, Louisiana

    DTIC Science & Technology

    1991-02-27

    balance of trade at this date. Planters owed over three million livres for previous shipments of slaves and supplies. By that time, structures within New...Delavigine (Lots 7 to 18). The frame buildings lying within the projected passage of Jourdan Avenue between Maurais and St. Claude, were purchased by...the top lends additional rigidity. It was also justified at South Halsted Street to provide machinists with quick passage from the top of one tower

  8. STS-103 crew perform virtual reality training in building 9N

    NASA Image and Video Library

    1999-05-24

    S99-05679 (24 May 1999) --- Astronauts Claude Nicollier (seated), representing the European Space Agency (ESA), and John M. Grunsfeld use virtual reality hardware to rehearse some of their duties for the upcoming STS-103 mission, NASA's third servicing visit to the Earth-orbiting Hubble Space Telescope (HST). The two mission specialists will be joined by five other astronauts, including a second ESA representative, for the STS-103 mission, scheduled for autumn of this year.

  9. Where Are They Now: Emily Burnett Aims Even Higher Thanks to Internship Experience | Poster

    Cancer.gov

    Emily Burnett, a five-time intern with NCI at Frederick’s Occupational Health Services (OHS), says the Werner H. Kirsten Student Intern Program program helped shape her current career trajectory. When she began her first OHS internship in 2015, her heart was set on becoming a nurse. However, after working with mentor Sarah Hooper and secondary mentor Patricia Claude, she decided to pursue a “higher level of medicine”—physician’s assistant.

  10. Space Shuttle Projects

    NASA Image and Video Library

    1999-07-01

    The STS-103 crew portrait includes (from left) C. Michael Foale, mission specialist; Claude Nicollier, mission specialist representing the European Space Agency (ESA) ; Scott J. Kelly, pilot; Curtis L. Brown, commander; and mission specialists Jean-Francois Clervoy (ESA), John M. Grunsfeld, and Steven L. Smith. Launched aboard the Space Shuttle Discovery on December 19, 1999 at 6:50 p.m. (CST), the STS-103 mission served as the third Hubble Space Telescope (HST) servicing mission.

  11. [Gender relations and interdependence: reflections on changes in the hospital configuration].

    PubMed

    Pereira, Audrey Vidal; Rotenberg, Lúcia; Oliveira, Simone Santos

    2013-01-01

    The article analyzes changes that have occurred in hospitals over the years, with a focus on the dynamics of gender relations as experienced by healthcare workers. We use the notions of configuration and interdependence, taken from Norbert Elias' theory of the civilizing process, along with discussions of gender relations at work; drawing from Michel Foucault, we also reference the disciplinary practices employed down through hospital history. This linkage of discussions on gender issues and on interdependent relations opens up to a reflection on conflicts of interests, power struggles, and the balance of tensions, which in turn makes it possible to problematize gender inequalities with the ultimate aim of achieving an interdisciplinary effort that will promote health care of an integral nature.

  12. Philosophical Approaches towards Sciences of Life in Early Cybernetics

    NASA Astrophysics Data System (ADS)

    Montagnini, Leone

    2008-07-01

    The article focuses on the different conceptual and philosophical approaches towards the sciences of life operating in the backstage of Early Cybernetics. After a short reconstruction of the main steps characterizing the origins of Cybernetics, from 1940 until 1948, the paper examines the complementary conceptual views between Norbert Wiener and John von Neumann, as a "fuzzy thinking" versus a "logical thinking", and the marked difference between the "methodological individualism" shared by both of them versus the "methodological collectivism" of most of the numerous scientists of life and society attending the Macy Conferences on Cybernetics. The main thesis sustained here is that these different approaches, quite invisible to the participants, were different, maybe even opposite, but they could provoke clashes, as well as cooperate in a synergic way.

  13. Bibliography on Cold Regions Science and Technology Volume 53, Part 2

    DTIC Science & Technology

    1999-12-01

    A.T. Claud, C. 53-1504 Interaction of ice floes with ships on offshore structures Case study of antarctic mesolow [1995, eng] 53-329 Coffey, M.T. [1992...in a dry-snow Dethloff, K Biogeochemistry of antarctic sea ice: a case study on avalanche [1998, eng] 53-2018 Climate variability in a nonlinear...concrete with respect to Effect of the Endicott Causeway on the population of Ferguson, M.E. frost resistance: a case study [1998, eng] 53-952 broad

  14. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hiebert, Ray; Hiebert, Roselyn

    This brief booklet gives a snapshot view of 25 men, each of whom contributed an important building block to the foundations of atomic science. The 25 men are: Anaxagoras; Archimedes; Avogadro, Amedeo; Berthollet, Claude Louis; Berzelius, Jons Jakob; Boyle, Robert; Bruno, Giordano; Copernicus; Dalton, John; Davy, Humphry; Democritus; Descartes, Rene; Empedocles; Fpicurus; Franklin, Benjamin; Galilei, Galileo; Gassendi, Pierre; Gay-Lussac, Joseph Louis; Lavoisier, Antoine; Leucippus; Lucretius; Newton, Isaac; Proust, Joseph Louis; Pythagoras; and Wollaston, William Hyde.

  15. STS-46 crewmembers participate in Fixed Base (FB) SMS training at JSC

    NASA Technical Reports Server (NTRS)

    1992-01-01

    STS-46 Atlantis, Orbiter Vehicle (OV) 104, Pilot Andrew M. Allen hands Mission Specialist (MS) and Payload Commander (PLC) Jeffrey A. Hoffman checklists from middeck locker MF43E during training session in JSC's fixed base (FB) shuttle mission simulator (SMS) located in Mission Simulation and Training Facility Bldg 5. European Space Agency (ESA) MS Claude Nicollier outfitted with communications kit assembly headset (HDST) and equipment looks beyond Hoffman to the opposite side of the middeck.

  16. [Alexis Carrell: the mystification ...].

    PubMed

    Vanderpooten, C

    1996-01-01

    Alexis Carrel is died in 1944. A half-century later, the most we know about his life comes from his widow. Pupil of the Jesuits, faith lost with Claude Bernard, recovered thanks to his wife, papers lefts to the Jesuits ..., all is well. Too beautiful edifying story to be true ... Details show that mystification trouble is in it. Who was, what thought exactly Carrel? Light may be shed only by an exhaustive study of his manuscripts and letters.

  17. Solar Sea Power Plants (SSPP): A critical review and survey

    NASA Technical Reports Server (NTRS)

    Strauss, A. M.

    1974-01-01

    An overview of technical and economic matters relating to the eventual success or failure of the SSPP concept is presented, with emphasis on the pollution and energy problems which the SSPP would serve to eliminate. Factors discussed include cost, mariculture possibilities, siting, legal limitations, design materials, mooring and anchoring, and the human element involved. Several alternative power systems are considered for incorporation into SSPP design, such as Nitinol power, Claude cycle, and closed cycle engine systems.

  18. (Meetings on the structure and properties of implanted ceramics)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    McHargue, C.J.; Horton, L.L.

    1990-01-01

    The visit to the University Claude Bernard was for the purpose of analyzing data obtained there and at ORNL in a collaborative research program, to exchange samples, to plan further work, and to revise drafts of two manuscripts for publication. One of the travelers served on the jury for the doctoral examination of E. Abonneau. The travelers also attended the NATO-ASI entitled Diamond and Diamond-Like Films and Coatings'' and served on the Organizing Committee.

  19. Is It in U.S. National Interests to Maintain Forward Deployed Military Forces in Asia

    DTIC Science & Technology

    2001-05-01

    also desires to purchase four Arleigh Burke -Class Guided Missile Destroyers (AEGIS) from the U.S. to provide it the capability to intercept China’s land...missile defense with the 7th Fleet’s two Aleigh Burke -Class Destroyers. Even if President George W. Bush’s Administration decides to sell Taiwan the...East, ed. Joe C. Dixon (Washington D.C.: U.S. Government Printing Office, 1980), 21. 16 Claude A. Buss , The United States and the Philippines

  20. STS-103 inflight crew portrait on the flight deck

    NASA Image and Video Library

    2000-01-28

    STS103-397-035 (19 - 27 December 1999) --- The seven astronauts aboard the Space Shuttle Discovery for NASA's third servicing visit to the Hubble Space Telescope (HST) pose for the traditional inflight crew portrait..In front are, from left, astronauts Claude Nicollier, Scott J. Kelly and John M. Grunsfeld. Behind them are.astronauts Steven L. Smith, C. Michael Foale, Curtis L. Brown, Jr., and Jean-Francois Clervoy. Nicollier and Clervoy are astronauts from the European Space Agency (ESA).

  1. STS-75 Payload Specialist Umberto Guidoni suits up

    NASA Technical Reports Server (NTRS)

    1996-01-01

    STS-75 Payload Specialist Umberto Guidoni (right) chats with fellow crew member Mission Specialist Claude Nicollier during suitup activities in the Operations and Checkout Building. Guidoni represents the Italian Space Agency and is one of three international crew members assigned to STS-75. He and six fellow crew members will depart shortly for Launch Pad 39B, where the Space Shuttle Columbia awaits liftoff during a two-and-a-half- hour launch window opening at 3:18 p.m. EST.

  2. Multiscale Materials Science - A Mathematical Approach to the Role of Defects and Uncertainty

    DTIC Science & Technology

    2016-10-28

    AFRL-AFOSR-UK-TR-2016-0034 Multiscale materials science - a mathematical approach to the role of defects and uncertainty Claude Le Bris ECOLE...science - a mathematical approach to the role of defects and uncertainty 5a.  CONTRACT NUMBER 5b.  GRANT NUMBER FA8655-13-1-3061 5c.  PROGRAM ELEMENT...1FORM SF 298 10/31/2016https://livelink.ebs.afrl.af.mil/livelink/llisapi.dll Contract FA 8655-13-1-3061 Multiscale materials science: a mathematical

  3. Magnitude Anomalies and Propagation of Local Phases

    DTIC Science & Technology

    1983-01-31

    PORTMSI 27 rue Claude Bernard 75005 PARIS - FRANCE AP()R h- ’,*174 2. SPOOSOtGINMONITAJNG AGENCY NAME(S) AND AOORIS,4ES) 1.SPONSONG/MOWTOFMG AFOSR DTBLDG...200SWJ There are three main parts in this report: - a study of magnitude anomalies in French Polynesia. A first approach gives an anomaly per station...which is roughly a function of a’zimuth valid for all French Polynesia plus a station’s constant. A more detailed study shows the influence of local

  4. Astronauts Chang-Diaz, Hoffman and Nicollier eating in their sleep racks

    NASA Image and Video Library

    1996-03-13

    STS075-302-016 (22 Feb.-9 March 1996) --- Soon after reaching Earth orbit, the blue shift team set up what they referred to as a "formal" meal on the space shuttle Columbia's middeck. Left to right are astronauts Franklin R. Chang-Diaz, STS-75 payload commander; Jeffrey A. Hoffman and Claude Nicollier, both mission specialists. Hoffman later told a gathering of Johnson Space Center employees that the meal was accompanied by classical music. Photo credit: NASA or National Aeronautics and Space Administration

  5. (Collaboration for improved understanding of implanted ceramics)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    McHargue, C.J.

    1990-04-09

    The visit to the University Claude Bernard was to analyze data obtained there and at ORNL in a collaborative research program, to exchange samples, to plan further work, and to prepare drafts of two manuscripts for publication. The traveler also attended a meeting of the organizers of a NATO-ASI entitled Diamond and Diamond-Like Films and Coatings'' that will be held in Italy in July--August 1990. The purpose of this organizing meeting was to establish the program and other organization details.

  6. We Bomb, Therefore We Are: The Evolution of Terrorist Group Life Cycles

    DTIC Science & Technology

    1994-03-24

    and arms robberies peaked during this phase, a marked qhift toward political action occurred. 𔃺°Quoted in Gilio , Tupamaros, 79 and 82. "•Ucbano...52. 蕀Quoted in Gilio , 120. 63 Claude Fly on 7 August 1970: and ended with abduction of British Ambassador Geoffrey Jackson on 8 January 1971...stabilize the present system "•’Quoted in della Porta, "Political Socialization," 273. 2 Quoted in Gilio , Tupamaros, 78. 2mIbid., 268. 14Ibid., 270. 124

  7. Symposium on Turbulent Shear Flows (8th) Held in Munich, Germany on 9-11 September 1991. Volume 2. Sessions 19-31, Poster Sessions

    DTIC Science & Technology

    1991-09-01

    FLAMES IN THE ATrR)S1]1 IERE USING A SECOND MOMNT TURBULENCE MODEL Hermilo RAMIREZ -LEON, Claude REY and Jean-Frangois SINI LABORATOIRE DE MECANIQUE DES...65 directly satisfied by an extended version of the C= F , ax6 aX5 artificial compressibility implicit method ( Ramirez -Leon et al,, 1991). 08 2 IR ap...the isotropization-of-production concept. For the compressible fluid case, Ramirez -Leon et al (1990) With regard to Eq (2), the right-hand side of

  8. 2nd EVA - MS Foale and Nicollier during FGS changeout

    NASA Image and Video Library

    1999-12-24

    STS103-501-026 (19 - 27 December 1999) --- Astronauts C. Michael Foale, left, and Claude Nicollier (on Discovery's robotic arm) install a Fine Guidance Sensor (FGS) into a protective enclosure in the Shuttle’s payload bay. Foale and Nicollier performed the second of three space walks to service the Hubble Space Telescope (HST) on the STS-103 mission. A large format camera inside Discovery's cabin was used to record this high-resolution image, while the Shuttle was orbiting above ocean and clouds.

  9. STS-75 Flight Day 10

    NASA Technical Reports Server (NTRS)

    1996-01-01

    On this tenth day of the STS-75 mission, the flight crew, Cmdr. Andrew Allen, Pilot Scott Horowitz, Payload Cmdr. Franklin Chang-Diaz, Payload Specialist Umberto Guidoni (Italy), and Missions Specialists Jeffrey Hoffman, Maurizio Cheli (ESA), and Claude Nicollier (ESA), are shown performing middeck and Microgravity lab experiments, including the Material pour l'Etude des Phenomenes Interessant la Solidification sur Terre et en Orbite (MEPHISTO) experiment, as well as some material burn tests. Earth views include cloud cover and horizon shots.

  10. Identification, Characterization and Clinical Development of the New Generation of Breast Cancer Susceptibility Alleles

    DTIC Science & Technology

    2007-03-01

    Gohrke S, SchŸrmann P, Bogdanova N, Dšrk T , Fagerholm R , Aaltonen K, Blomqvist C, Nevanlinna H, Seal S, Renwick A, Stratton MR, Rahman N, Sangrajrang...Easton DF, Sodha N, Seal S, Barfoot R , Mangion J, Chang-Claude J, Eccles D, Eeles RA, Evans DG, Houlston RS, Murday VA, Narod S, Peretz T , Peto J...Barfoot R , Chagtai T , Jayatilake H, McGuffog L, Hanks S, Evans DG, Eccles D, The Breast Cancer Susceptibility Collaboration (UK), Easton DF and

  11. STS103-S-002

    NASA Image and Video Library

    1999-08-01

    STS103-S-002 (August 1999) --- These seven astronauts have been assigned as crew members for NASA's third servicing mission to the Hubble Space Telescope (HST). They are, from the left, astronauts C. Michael Foale, Claude Nicollier, Scott J. Kelly, Curtis L. Brown, Jr., Jean-Francois Clervoy, John M. Grunsfeld and Steven L. Smith. Brown and Kelly are commander and pilot, respectively. All the others are mission specialists (MS), with international MS Nicollier and Clervoy representing the European Space Agency (ESA).

  12. BKCASE(TM) Body of Knowledge and Curriculum to Advance Systems Engineering

    DTIC Science & Technology

    2010-04-28

    Lawson, Lawson Konsult AB, Sweden Johann Amsenga, Eclipse RDC, South Africa Alex Lee , Defence Science and Technology Agency, Singapore Erik Aslaksen...Engineering Division, US Tim Ferris, University of South Australia and INCOSE, Australia Jean-Claude Roussel, EADS, France Kevin Forsberg, Center for...Systems Management and INCOSE, US Sven-Olaf Schulze, Berner & Mattner Systemtechnik GmbH, Germany Richard Freeman, Air Force Center for Systems

  13. Colloquium on High Resolution Molecular Spectroscopy (8th), 19-23 September 1983 (Colloque sur la Spectroscopie Moleculaire a Haute Resolution (Huitieme), 19-23 Septembre 1983).

    DTIC Science & Technology

    1983-09-23

    avec lea autres State. A FITTING PROCEDURE FOP EXTENSIVELY PERTURBED HAMILTONIANS APPLICATION TO THE A1I- STATE OF CO ANDRE LE FLOCH AND JEAN MASSON...BENICHOU, Jean -Claude DEROCHE Laboratoire d’Infrarouge, Associg au C.N.R.S. Universitf de Paris-Sud, Bitiment 350 91405 ORSAY Cfdex, France Le pompage...MEUDON, FRANCE and Jean -Yves RONCIN Equipe de Spectroscopie, C.N.R.S. (L.A. 171, Universitis de Lyon I et Saint-Etienne) 158 bis Cours Fauriel, 42023

  14. Macromolecules and Enzymes: The Geneva Heritage from Kurt H. Meyer and Edmond H. Fischer.

    PubMed

    Fischer, Edmond H; Piguet, Alfred

    2009-12-01

    On the 26th May 2009, Edmond Fischer, winner with Ed Krebs of the Nobel prize in physiology or medicine in 1992, and his colleague at the time of his research activities at the Ecole de chimie of the University of Geneva, Alfred Piguet, met with Andreas Hauser, Claude Piguet and Howard Riezman of the Section de chimie et biochimie of the University of Geneva to talk about how they became scientists under the impetus of Kurt H. Meyer and what became of them thereafter.

  15. Control of defect localization in crystalline wrinkling by curvature and topology

    NASA Astrophysics Data System (ADS)

    Lopez Jimenez, Francisco

    We investigate the influence of curvature and topology on crystalline wrinkling patterns in generic elastic bilayers. Our numerical analysis predicts that the total number of defects created by adiabatic compression exhibits universal quadratic scaling for spherical, ellipsoidal and toroidal surfaces over a wide range of system sizes. However, both the localization of individual defects and the orientation of defect chains depend strongly on the local Gaussian curvature and its gradients across a surface. Our results imply that curvature and topology can be utilized to pattern defects in elastic materials, thus promising improved control over hierarchical bending, buckling or folding processes. Generally, this study suggests that bilayer systems provide an inexpensive yet valuable experimental test-bed for exploring the effects of geometrically induced forces on assemblies of topological charges. Joint work with Norbert Stoop, Romain Lagrange, Jorn Dunkel and Pedro M. Reis.

  16. F.S.V.B. Volleyball

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None

    2006-06-07

    22me assemblée des délégués de la Fédération Suisse de Volley Ball (F.S.V.B.), en présence entre autres de Claude Delay, représentant de la société fédérale de gymnastique et Hans Gauer, représentant de l'association suisse de gymnastique féminine. Annonce d'une démonstration d'un mini match de volley ball à Meyrin dans l'après-midi.

  17. The Recognition of Words from Phonemes in Continuous Speech.

    DTIC Science & Technology

    1981-12-01

    C A BAKER UNCLASSIFIED AFIT/GE/EE/810ŝ NL EEEEEEIIEEEEI EEEEEEEEEEEEEE EEEEIIEEEIIEI IIIEEEEIIEIIEE EIEEEEEEEEIIEE IIIEIIEEEEEEEE r- ~. 7 c ~ F IVV...82 06 16 011 AFIT/GE/EE/ 81 D -9 THE RECOGNITION OF WORDS FROM PHONEMES IN CONTINUOUS SPEECH THESIS AFIT/GE/EE/81D-9 Claude A. Baker Captain USAF...33. OU Qbey 14. ZX zoo 34. UX foot 15. SH 5h e 35. UU b.Qt 16. ZH azure 36. UH up 17. MX me 37. UH about 18. NX no 38. ER woQrd 19. NG sinkg 39. XX NA

  18. Various view with fish-eye lens of STS-103 crew on aft flight deck

    NASA Image and Video Library

    2000-01-28

    STS103-375-019 (19-27 December 1999) ---.Six members of the STS-103 crew are seen in this "fish-eye" lens scene taken on Discovery's flight deck during the deployment of the Hubble Space Telescope (HST). From left are astronauts Jean-Francois Clervoy, C. Michael Foale, Claude Nicollier, Curtis L. Brown, Jr., John M. Grunsfeld and Scott J. Kelly. Brown and Kelly are commander and pilot, respectively. All the others are mission specialists, with international MS Nicollier and Clervoy representing the European Space Agency (ESA). Astronaut Steven L. Smith, payload commander, took the photo.

  19. BKCASE (trademark): Body of Knowledge and Curriculum to Advance Systems Engineering

    DTIC Science & Technology

    2010-10-01

    Association Francaise d‘lingeniere Systeme, France Tim  Ferris University of South Australia, Australia Kevin Forsberg Center for Systems Management US 7... Lee Defence Science and Technology Agency,  Singapore Ray Madachy Naval Postgraduate School, US James Martin Aerospace Corporation US    ,  Greg...Pyster Stevens Institute of Technology, US Garry Roedler Lockheed Martin, US Jean‐Claude Roussel EADS, France 9/2010 Sven‐Olaf Schulze Berner & Mattner

  20. Felt stigma and obesity: introducing the generalized other.

    PubMed

    Barlösius, Eva; Philipps, Axel

    2015-04-01

    People with a big body are tainted in western societies. Although most research on obesity occurs in the medical context, few studies investigate characteristics and effects of feelings and fears related to the fat stigma in the absence of overt discrimination. By linking Norbert Elias's and George H. Mead's theoretical frameworks, this paper offers a different approach to understanding and investigating felt stigma. The study is based on secondary data (25 semistructured interviews with children and adolescents). It explores internalized societal perspectives on overweight and obesity and inquires into the way in which interviewees handle the blame frame of personal responsibility during their interview. The preliminary findings suggest that specific forms of managing one's self-presentation in interviews indicate felt stigma. Consequently, the paper argues for an analytical approach that extends the focus on the content of interviews to include its dynamics. Copyright © 2015 Elsevier Ltd. All rights reserved.

  1. Proceedings of: 2005 Particle Acceleration Confence

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Henderson, Stuart

    2006-01-01

    The 21st Particle Accelerator Conference, PAC05, took place at the Knoxville Convention Center (KCC) from Monday through Friday, May 16-20, 2005. Sponsored by the American Physical Society (APS), the Institute of Electrics and Electronics Engineers (IEEE) with its subdivision of Nuclear and Plasma Sciences Society (NPSS), the conference was hosted by the Oak Ridge National Laboratory (ORNL) Spallation Neutron Source (SNS) Project and Thomas Jefferson National Accelerator Facility (JLab). The conference was chaired by Norbert Holtkamp, and the Local Organizing Committee was made up of staff from the ORNL SNS Project under the chairmanship of Stuart Henderson. The conference welcomedmore » over 1400 delegates from the United States, Europe, Asia, the Middle East, South America and from as far away as Australia. Almost 1400 papers where processed during the conference and will be published on the Joint Accelerator Conferences Website (JACoW) page.« less

  2. Isolation and Characterization of a Toxic Moiety of Low Molecular Weight from Clostridium botulinum Type A

    PubMed Central

    Gerwing, Julia; Dolman, Claude E.; Bains, Hardial S.

    1965-01-01

    Gerwing, Julia (The University of British Columbia, Vancouver, B.C., Canada), Claude E. Dolman, and Hardial S. Bains. Isolation and characterization of a toxic moiety of low molecular weight from Clostridium botulinum type A. J. Bacteriol. 89:1383–1386. 1965.—A toxic moiety of low molecular weight has been isolated from a type A strain of Clostridium botulinum, by a method involving ammonium sulfate precipitation and elution through diethylaminoethyl cellulose at pH 5.6. By means of electrophoresis and ultracentrifugation, the toxic substance was shown to be homogeneous; a molecular weight of 12,200 was calculated. Images PMID:14293025

  3. Physics in the Art Museum

    NASA Astrophysics Data System (ADS)

    Dale, Daniel A.; Bailey, Brenae L.

    2003-02-01

    Parisian artist Paul Signac met the impressionists Claude Monet and Georges Seurat in 1884. Their influence spurred his work in pointillism (or, where the juxtaposition of small dots of color in conjunction with the limited resolving power of the human eye lead to the impression of color coalescence).1-4 To stimulate a cross-disciplinary appreciation of science and art, we used the University of Wyoming Art Museum's Signac painting "Barques de Pêche à Marseilles" (see Fig. 1) to explore diffraction theory and the anatomical limitations to our vision during an optics exercise done in the museum.

  4. ["Kaitai-Shinsho": a change of languages and concepts].

    PubMed

    Okada, Masanobu

    2003-07-01

    The translation of "Outleedkundige Tafelen (Dutch) [Anatomische Tabellen (German)]" to "Kaitai-Shinsho" by Gempaku Sugita and others was not the mere substitution of Dutch for Japanese. They responded to the writing according to the situation of the change to modern medicine from the medicine of ancient-medieval times based on Galen's teachings, by using the Japanese culture of those days in a form of "bricolage" (a term used by Claude Levi-Strauss), in combination with Western medicine, leading to its establishment as Japanese medicine. That is, their work was not a mere translation, but an innovation of Japanese medical language system.

  5. STS-46 ESA MS Nicollier conducts IFM on OV-104's waste collection system

    NASA Technical Reports Server (NTRS)

    1992-01-01

    STS-46 European Space Agency (ESA) Mission Specialist (MS) Claude Nicollier, wearing goggles, face mask, and rubber gloves, reviews inflight maintenance (IFM) checklist procedures before starting waste collection system (WCS) fan separator repair. One of two fan separators used to transfer waster water from the waste management compartment (WMC) to the waste water tank has failed. The suspected accumulation of water in the separator was believed to have occurred during a test dumping of waste water at a lower than normal pressure to evaluate the performance of new nozzles. The WMC is located on the middeck of Atlantis, Orbiter Vehicle (OV) 104.

  6. Early Rockets

    NASA Image and Video Library

    2004-04-15

    During the 19th century, rocket enthusiasts and inventors began to appear in almost every country. Some people thought these early rocket pioneers were geniuses, and others thought they were crazy. Claude Ruggieri, an Italian living in Paris, apparently rocketed small animals into space as early as 1806. The payloads were recovered by parachute. As depicted here by artist Larry Toschik, French authorities were not always impressed with rocket research. They halted Ruggieri's plans to launch a small boy using a rocket cluster. (Reproduced from a drawing by Larry Toschik and presented here courtesy of the artist and Motorola Inc.)

  7. ON THE PRAGMATICS OF SOCIAL THEORY: THE CASE OF ELIAS'S "ON THE PROCESS OF CIVILIZATION".

    PubMed

    DA Silva, Filipe Carreira; Bucholc, Marta

    2016-09-01

    This paper proposes a new approach to the study of sociological classics. This approach is pragmatic in character. It draws upon the social pragmatism of G. H. Mead and the sociology of texts of D. F. McKenzie. Our object of study is Norbert Elias's On the Process of Civilization. The pragmatic genealogy of this book reveals the importance of taking materiality seriously. By documenting the successive entanglements between human agency and nonhuman factors, we discuss the origins of the book in the 1930s, how it was forgotten for 30 years, and how in the mid-1970s it became a sociological classic. We explain canonization as a matter of fusion between book's material form and its content, in the context of the paperback revolution of the 1960s, the events of May 1968, and the demise of Parsons' structural functionalism, and how this provided Elias with an opportunity to advance his model of sociology. © 2016 Wiley Periodicals, Inc.

  8. Heliophysics: Active Stars, their Astrospheres, and Impacts on Planetary Environments

    NASA Astrophysics Data System (ADS)

    Schrijver, C. J.; Bagenal, F.; Sojka, J. J.

    2016-04-01

    Preface; 1. Introduction Carolus J. Schrijver, Frances Bagenal and Jan J. Sojka; 2. Solar explosive activity throughout the evolution of the Solar System Rachel Osten; 3. Astrospheres, stellar winds, and the interstellar medium Brian Wood and Jeffrey L. Linsky; 4. Effects of stellar eruptions throughout astrospheres Ofer Cohen; 5. Characteristics of planetary systems Debra Fischer and Ji Wang; 6. Planetary dynamos: updates and new frontiers Sabine Stanley; 7. Climates of terrestrial planets David Brain; 8. Upper atmospheres of the giant planets Luke Moore, Tom Stallard and Marina Garland; 9. Aeronomy of terrestrial upper atmospheres David E. Siskind and Stephen W. Bougher; 10. Moons, asteroids, and comets interacting with their surroundings Margaret G. Kivelson; 11. Dusty plasmas Mihály Horányi; 12. Energetic-particle environments in the Solar System Norbert Krupp; 13. Heliophysics with radio scintillation and occultation Mario M. Bisi; Appendix 1. Authors and editors; List of illustrations; List of tables; References; Index.

  9. [Project HOPE contribution to the setting up of the professional identity of the first nurses from Alagoas, 1973-1977].

    PubMed

    Costa, Laís de Miranda Crispim; dos Santos, Regina Maria; Santos, Tânia Cristina Franco; Trezza, Maria Cristina Soares Figueiredo; Leite, Josete Luzia

    2014-01-01

    Social-historical study conducted to examine the contribution of the American Nurses of Project HOPE to the configuration of the professional identity of the first trained nurses in Alagoas, in the period of 1973-1977. The theoretical framework was the "Civilizing Process" of Norbert Elias. Primary sources were official documents and personal files of 13 respondents by oral history; the secondary sources were authors of the History of Brazil/Alagoas. Data analysis showed that the configuration of the professional identity of the first trained nurses in Alagoas was a civilizing process, with all the nuances that make up the power relations. There was a significant contribution of American Nursing. However the movement of resistance to this domination was very strong, resulting in a Course that could take advantage of technological advancement and prestige brought by the United States, to build a unique Nursing from the social fabric embroidery at this meeting with so many different cultures.

  10. List of participants at SIDE IV meeting, Tokyo, 27 November--1 December 2000

    NASA Astrophysics Data System (ADS)

    2001-12-01

    Mark J Ablowitz, Vsevolod Adler, Mark Alber, Said Belmehdi, Marco Boiti, Claude Brezinski, R Bullough, Y M Chiang, Theodore Chihara, Peter A Clarkson, Robert Conte, Adam Doliwa, Vladimir Dorodnitsyn, Mitsuaki Eguchi, Claire Gilson, Basil Grammaticos, Valeri Gromak, Rod Halburd, Koji Hasegawa, Jarmo Hietarinta, Ryogo Hirota, Xing Biao Hu, M Idzumi, J Inoguchi, Hiroya Ishikara, Mourad Ismail, Shin Isojima, Kenichi Ito, Yoshiaki Itoh, Masashi Iwasaki, Klara Janglajew, Michio Jimbo, Nalini Joshi, Kenji Kajiwara, Saburo Kakei, Masaru Kamata, Satoshi Kamei, Rinat Kashaev, Shingo Kawai, Taeko Kimijima, K Kimura, Anatol Kirillov, Koichi Kondo, Boris Konopelchenko, Martin Kruskal, Atsuo Kuniba, Wataru Kunishima, Franklin Lambert, Serguei Leble, Decio Levi, Shigeru Maeda, Manuel Manas, Ken-Ichi Maruno, Tetsu Masuda, J Matsukidaira, Atsushi Matsumiya, Shigeki Matsutani, Yukitaka Minesaki, Mikio Murata, Micheline Musette, Atsushi Nagai, Katsuya Nakagawa, Atsushi Nakamula, Akira Nakamura, Yoshimasa Nakamura, Frank Nijhoff, J J C Nimmo, Katsuhiro Nishinari, Michitomo Nishizawa, A Nobe, Masatoshi Noumi, Yaeko Ohsaki, Yasuhiro Ohta, Kazuo Okamoto, Alexandre Orlov, Naoki Osada, Flora Pempinelli, Spiro Pyrlis, Reinout Quispel, Orlando Ragnisco, Alfred Ramani, Jean-Pierre Ramis, Andreas Ruffing, Simon Ruijsenaars, Satoru Saito, Noriko Saitoh, Hidetaka Sakai, Paulo Santini, Narimasa Sasa, Ryu Sasaki, Yoshikatsu Sasaki, Junkichi Satsuma, Sergei Sergeev, Nobuhiko Shinzawa, Evgueni Sklyanin, Juris Suris, Norio Suzuki, Yukiko Tagami, Katsuaki Takahashi, Daisuke Takahashi, Tomoyuki Takenawa, Yoshiro Takeyama, K M Tamizhmani, T Tamizhmani, Kouichi Toda, Morikatsu Toda, Tetsuji Tokihiro, Takayuki Tsuchida, Yohei Tsuchiya, Teruhisa Tsuda, Satoru Tsujimoto, Walter Van Assche, Claude Viallet, Luc Vinet, Shinsuke Watanabe, Yoshihida Watanabe, Ralph Willox, Pavel Winternitz, Yasuhiko Yamada, Yuji Yamada, Jin Yoneda, Haruo Yoshida, Katsuhiko Yoshida, Daisuke Yoshihara, Fumitaka Yura, J

  11. The Space Shuttle Columbia clears the tower to begin the mission. The liftoff occurred on schedule

    NASA Technical Reports Server (NTRS)

    1996-01-01

    STS-75 LAUNCH VIEW --- The Space Shuttle Columbia clears the tower to begin the mission. The liftoff occurred on schedule at 3:18:00 p.m. (EST), February 22, 1996. Visible at left is the White Room on the orbiter access arm through which the flight crew had entered the orbiter. Onboard Columbia for the scheduled two-week mission were astronauts Andrew M. Allen, commander; Scott J. Horowitz, pilot; Franklin R. Chang-Diaz, payload commander; and astronauts Maurizio Cheli, Jeffrey A. Hoffman and Claude Nicollier, along with payload specialist Umberto Guidioni. Cheli and Nicollier represent the European Space Agency (ESA), while Guidioni represents the Italian Space Agency (ASI).

  12. A remote camera at Launch Pad 39B, at the Kennedy Space Center (KSC), recorded this profile view of

    NASA Technical Reports Server (NTRS)

    1996-01-01

    STS-75 LAUNCH VIEW --- A remote camera at Launch Pad 39B, at the Kennedy Space Center (KSC), recorded this profile view of the Space Shuttle Columbia as it cleared the tower to begin the mission. The liftoff occurred on schedule at 3:18:00 p.m. (EST), February 22, 1996. Onboard Columbia for the scheduled two-week mission were astronauts Andrew M. Allen, commander; Scott J. Horowitz, pilot; Franklin R. Chang-Diaz, payload commander; and astronauts Maurizio Cheli, Jeffrey A. Hoffman and Claude Nicollier, along with payload specialist Umberto Guidioni. Cheli and Nicollier represent the European Space Agency (ESA), while Guidioni represents the Italian Space Agency (ASI).

  13. F.S.V.B. Volleyball

    ScienceCinema

    None

    2017-12-09

    22me assemblée des délégués de la Fédération Suisse de Volley Ball (F.S.V.B.), en présence entre autres de Claude Delay, représentant de la société fédérale de gymnastique et Hans Gauer, représentant de l'association suisse de gymnastique féminine. Annonce d'une démonstration d'un mini match de volley ball à Meyrin dans l'après-midi.

  14. View of Southern Cross, Alpha and Beta Centauri

    NASA Image and Video Library

    1996-03-18

    STS075-351-022 (22 Feb.- 9 March 1996) --- The space shuttle Columbia's vertical stabilizer appears to point to the four stars of the Southern Cross. The scene was captured with a 35mm camera just prior to a sunrise. The seven member crew was launched aboard the space shuttle Columbia on Feb. 22, 1996, and landed on March 9, 1996. Crew members were Andrew M. Allen, mission commander; Scott J. Horowitz, pilot; Franklin R. Chang-Diaz, payload commander; and Maurizio Cheli, European Space Agency (ESA); Jeffrey A. Hoffman and Claude Nicollier, ESA, all mission specialists; along with payload specialist Umberto Guidoni of the Italian Space Agency (ASI).

  15. Tethered Satellite System (TSS)-1R survey photography

    NASA Image and Video Library

    1996-03-18

    STS075-325-014 (25 Feb. 1996) --- The frayed end of the tether portion of the Tethered Satellite System (TSS) is seen at the end of the supportive boom. On February 25, 1996, the crew deployed the TSS, which later broke free. The seven member crew was launched aboard the Space Shuttle Columbia on February 22, 1996, and landed on March 9, 1996. Crewmembers were Andrew M. Allen, mission commander; Scott J. Horowitz, pilot; Franklin R. Chang-Diaz, payload commander; and Maurizio Cheli, European Space Agency (ESA); Jeffrey A. Hoffman and Claude Nicollier (ESA), all mission specialists; along with payload specialist Umberto Guidoni of the Italian Space Agency (ASI).

  16. View of the TSS-1R after the tether broke

    NASA Image and Video Library

    1996-04-03

    STS075-360-021 (22 Feb.- 9 March 1996) --- The loose tether forms a faint diagonal line in this scene recorded on a later fly-by. On Feb. 25, 1996, the crew deployed the Tethered Satellite System (TSS), which later broke free. The seven member crew was launched aboard the space shuttle Columbia on Feb. 22, 1996, and landed on March 9, 1996. Crew members were Andrew M. Allen, mission commander; Scott J. Horowitz, pilot; Franklin R. Chang-Diaz, payload commander; and Maurizio Cheli, European Space Agency (ESA); Jeffrey A. Hoffman and Claude Nicollier, ESA, all mission specialists; along with payload specialist Umberto Guidoni of the Italian Space Agency (ASI).

  17. Official portrait of the STS-46 Atlantis, Orbiter Vehicle (OV) 104, crew

    NASA Image and Video Library

    1999-02-26

    STS046-S-002 (May 1992) --- The crew members assigned to the STS-46 mission pose with seven flags that represent participation on the flight. Loren J. Shriver (right front) is mission commander; Andrew M. Allen (left front) is pilot. Others are (left to right) Marsha S. Ivins, mission specialist; Claude Nicollier, mission specialist representing the European Space Agency (ESA); Jeffrey A. Hoffman, payload commander; Franklin R. Chang-Diaz, mission specialist; and Franco Malerba, flying for the Italian Space Agency (ASI). The flags, left to right, represent the United States of America, Costa Rica (Chang's native country), Italy, Switzerland (Nicollier's homeland), NASA, ESA and ASI.

  18. STS-46 ESA MS Nicollier and PLC Hoffman pose on OV-104's aft flight deck

    NASA Technical Reports Server (NTRS)

    1992-01-01

    STS-46 European Space Agency (ESA) Mission Specialist (MS) Claude Nicollier (left) and MS and Payload Commander (PLC) Jeffrey A. Hoffman pose in front of the onorbit station controls on the aft flight deck of Atlantis, Orbiter Vehicle (OV) 104. The overhead windows W7 and W8 appear above their heads and the aft flight deck viewing windows W9 and W10 behind them. Hoffman and Nicollier have been training together for a dozen years at JSC. Hoffman was an astronaut candidate in 1978 and Nicollier accompanied a group of trainees in 1980. Note the partially devoured chocolate Space Shuttle floating near the two.

  19. From Claude Bernard to the Batcave and beyond: using Batman as a hook for physiology education.

    PubMed

    Zehr, E Paul

    2011-03-01

    Communicating physiology to the general public and popularizing science can be tremendously rewarding activities. Providing relevant and compelling points of linkage, however, between the scientific experiences and the interests of the general public can be challenging. One avenue for popularizing science is to link scientific concepts to images, personalities, and icons in popular culture. Currently, comic book superhero movies and television shows are extremely popular, and Batman was used as the vehicle for popularizing concepts of exercise science, neuroscience, and physiology in my recent book, Becoming Batman: the Possibility of a Superhero. The objective of this book was to bring scientific understanding to the broader public by using the physical image and impression everyone has of Batman and his abilities and then connecting this to the underlying science. The objective of this article is to share some of the details of the process and the positive and negative outcomes of using such an approach with other academics who may be interested in similar activities. It is my goal that by sharing this experience I may stimulate like-minded readers to initiate their own similar projects and to also be emboldened to try and integrate popular culture touchstones in their own teaching practice.

  20. From Claude Bernard to the Batcave and Beyond: Using Batman as a Hook for Physiology Education

    ERIC Educational Resources Information Center

    Zehr, E. Paul

    2011-01-01

    Communicating physiology to the general public and popularizing science can be tremendously rewarding activities. Providing relevant and compelling points of linkage, however, between the scientific experiences and the interests of the general public can be challenging. One avenue for popularizing science is to link scientific concepts to images,…

  1. Jupiter Red 'Monet'

    NASA Image and Video Library

    2017-08-30

    Citizen scientist David Englund created this avant-garde Jovian artwork using data from the JunoCam imager on NASA's Juno spacecraft. The unique interpretation of Jupiter's Great Red Spot was done in a style that pays tribute to French Impressionist painter Claude Monet. The original image was taken on July 10, 2017 at 7:12 p.m. PDT (10:12 p.m. EDT), as the Juno spacecraft performed its 7th close flyby of Jupiter. At the time the image was taken, the spacecraft was 10,274 miles (16,535 kilometers) from the tops of the clouds of the planet, at a latitude of -36.9 degrees. https://photojournal.jpl.nasa.gov/catalog/PIA21779

  2. An analysis of concert saxophone vibrato through the examination of recordings by eight prominent soloists

    NASA Astrophysics Data System (ADS)

    Zinninger, Thomas

    This study examines concert saxophone vibrato through the analysis of several recordings of standard repertoire by prominent soloists. The vibrato of Vincent Abato, Arno Bornkamp, Claude Delangle, Jean-Marie Londeix, Marcel Mule, Otis Murphy, Sigurd Rascher, and Eugene Rousseau is analyzed with regards to rate, extent, shape, and discretionary use. Examination of these parameters was conducted through both general observation and precise measurements with the aid of a spectrogram. Statistical analyses of the results provide tendencies for overall vibrato use, as well as the effects of certain musical attributes (note length, tempo, dynamic, range) on vibrato. The results of this analysis are also compared among each soloist and against pre-existing theories or findings in vibrato research.

  3. Bandwidth efficient coding: Theoretical limits and real achievements. Error control techniques for satellite and space communications

    NASA Technical Reports Server (NTRS)

    Costello, Daniel J., Jr.; Courturier, Servanne; Levy, Yannick; Mills, Diane G.; Perez, Lance C.; Wang, Fu-Quan

    1993-01-01

    In his seminal 1948 paper 'The Mathematical Theory of Communication,' Claude E. Shannon derived the 'channel coding theorem' which has an explicit upper bound, called the channel capacity, on the rate at which 'information' could be transmitted reliably on a given communication channel. Shannon's result was an existence theorem and did not give specific codes to achieve the bound. Some skeptics have claimed that the dramatic performance improvements predicted by Shannon are not achievable in practice. The advances made in the area of coded modulation in the past decade have made communications engineers optimistic about the possibility of achieving or at least coming close to channel capacity. Here we consider the possibility in the light of current research results.

  4. An assessment of the costs and benefits of interventions aimed at improving rural community water supplies in developed countries.

    PubMed

    Hunter, Paul R; Pond, Kathy; Jagals, Paul; Cameron, John

    2009-06-01

    We report a cost benefit analyses (CBA) for water interventions in rural populations of developed country sub-regions. A Bayesian belief network was used to estimate the cost benefit ratio using Monte Carlo simulation. Where possible we used input data from recently published primary research or systematic reviews. Otherwise variables were derived from previous work in the peer-reviewed or grey literature. For these analyses we considered the situation of people with small and very small community supplies that may not be adequately managed. For the three developed country sub-regions Amr-A (America region A), Eur-A (European region A) and Wpr-A (Western Pacific region A), we estimate the costs of acute diarrhoeal illness associated with small community supplies to be U$4671 million (95% CI 1721-9592), the capital costs of intervention to be USD 13703 million (95% CI 6670-20735), additional annual maintenance to be USD 804 million (95%CI 359-1247) and the CB ratio to be 2.78 (95%CI 0.86-6.5). However, we also estimated the cost of post infectious irritable bowel syndrome (IBS) following drinking water-associated acute gastroenteritis to be USD 11896 million (95%CI 3118-22657). When the benefits of reduced IBS are added to the analysis the CB ratio increases to 9.87 (95%CI 3.34-20.49). The most important driver of uncertainty was the estimate of the cost of illness. However, there are very few good estimates of costs in improving management of small rural supplies in the literature. Investments in drinking-water provision in rural settings are highly cost beneficial in the developed world. In the developed world, the CB ratio is substantially positive especially once the impact of IBS is included.

  5. Isolation and characterization of a β-propeller gene containing phosphobacterium Bacillus subtilis strain KPS-11 for growth promotion of potato (Solanum tuberosum L.)

    PubMed Central

    Hanif, Muhammad Kashif; Hameed, Sohail; Imran, Asma; Naqqash, Tahir; Shahid, Muhammad; Van Elsas, Jan D.

    2015-01-01

    Phosphate-solubilizing and phytate-mineralizing bacteria collectively termed as phosphobacteria provide a sustainable approach for managing P-deficiency in agricultural soils by supplying inexpensive phosphate to plants. A phosphobacterium Bacillus subtilis strain KPS-11 (Genbank accession no. KP006655) was isolated from potato (Solanum tuberosum L.) rhizosphere and characterized for potato plant growth promoting potential. The strain utilized both Ca-phosphate and Na-phytate in vitro and produced 6.48 μg mL-1 indole-3-acetic acid in tryptophan supplemented medium. P-solubilization after 240 h was 66.4 μg mL-1 alongwith the production of 19.3 μg mL-1 gluconic acid and 5.3 μg mL-1 malic acid. The extracellular phytase activity was higher (4.3 × 10-10 kat mg-1 protein) than the cell-associated phytase activity (1.6 × 10-10 kat mg-1 protein). B. subtilis strain KPS-11 utilized 40 carbon sources and showed resistance against 20 chemicals in GENIII micro-plate system demonstrating its metabolic potential. Phytase-encoding gene β-propeller (BPP) showed 92% amino acid similarity to BPP from B. subtilis (accession no.WP_014114128.1) and 83% structural similarity to BPP from B. subtilis (accession no 3AMR_A). Potato inoculation with B. subtilis strain KPS-11 increased the root/shoot length and root/shoot weight of potato as compared to non-inoculated control plants. Moreover, rifampicin-resistant derivative of KPS-11 were able to survive in the rhizosphere and on the roots of potato up to 60 days showing its colonization potential. The study indicates that B. subtilis strain KPS-11 can be a potential candidate for development of potato inoculum in P-deficient soils. PMID:26106383

  6. Living autobiographically: Concepts of aging and artistic expression in painting and modern dance.

    PubMed

    Banerjee, Mita; Wohlmann, Anita; Dahm, Ralf

    2017-01-01

    This article discusses the ways in which artists have incorporated or failed to incorporate the aging process of their bodies into their art. Using Russian ballet dancer Mikhail Baryshnikov and the French painter Claude Monet as cases in point, we explore situations in which physical changes brought about by aging compromises artists' ability to engage with their artistic medium. Connecting Monet's oeuvre and Baryshnikov's dance performances to life writing accounts, we draw on John Paul Eakin's concept of "living autobiographically": In this vein, life writing research does not only have to take into account concepts of identity as they emerge from life writing narratives, but it also needs to explore the somatic, corporeal and material dimensions of these narratives. Copyright © 2016. Published by Elsevier Inc.

  7. Messier, Copernicus, Flamsteed: The SAF Rare-Book Collection in Paris

    NASA Astrophysics Data System (ADS)

    Pasachoff, Jay M.

    2014-01-01

    The historic books belonging to the Société Astronomique de France, founded by Camille Flammarion in 1887, are located partly in Paris and partly at the Flammarion site in Juvisy, a Paris suburb. Their holdings include first editions of Copernicus's De Revolutionibus and of Flamsteed's star atlas, as well as Messier's own copy of his 1783 and 1784 papers with his handwritten comments and additions. I will describe the fruitless search for a Bevis atlas and the circumstances that led me to inspect these treasures. I thank David Valls-Gabaud and Philippe Morel of the Société Astronomique de France for their hospitality in Paris, Jean-Claude Pecker, and Owen Gingerich for his prior work on Messier's catalogue.

  8. An Englishman abroad: Charles Blagden's visit to Paris in 1783.

    PubMed

    Fauque, Danielle M E

    2008-12-20

    Once the preliminaries of peace had been signed in January 1783, after the war of American independence, exchanges between British and French men of science resumed their normal course. On a visit to Paris in 1783, the francophile Charles Blagden (with the encouragement of Joseph Banks) made a number of contacts that fostered relations between the Royal Society and the Académie royale des sciences. In the course of this and several subsequent visits to France, Blagden became especially intimate with the chemist Claude-Louis Berthollet. His correspondence, now in the Royal Society, is a rich source for our understanding of some of the leading scientific debates of the day, in particular concerning the nature of water, which forms the main subject of this article.

  9. An introduction to the medical epistemology of Georges Canguilhem: moving beyond Michel Foucault.

    PubMed

    Spicker, S F

    1987-11-01

    Although American philosophers and physicians are generally familiar with the writings of Claude Bernard (1813-1878), especially his Introduction to the Study of Experimental Medicine (1865), the medical epistemology of Georges Canguilhem, born in 1904, is virtually unknown in English speaking nations. Although indebted to Bernard for his conception of the methods to be employed in the acquisition of medical knowledge, Canguilhem radically reformulates Bernard's concepts of 'disease', 'health', 'illness', and 'pathology'. Contemporary exhortations to medical professionals and medical students that they "pay more attention to the whole patient" take on significance in working through the writings of Canguilhem; of crucial importance is the relation that obtains between a patient's unique symptomatology and the proper drug regiment that is required.

  10. STS-103 Crew at Breakfast, Suiting, Departing O&C

    NASA Technical Reports Server (NTRS)

    1999-01-01

    The Hubble Space Telescope (HST) team is preparing for NASA's third scheduled service call to Hubble. This mission, STS-103, will launch from Kennedy Space Center aboard the Space Shuttle Discovery. The seven flight crew members for STS-103 are: Commander Curtis L. Brown (his sixth flight), Pilot Scott J. Kelly and European Space Agency (ESA) astronaut Jean-Francois Clervoy (his third flight) will join space walkers Steven L. Smith (his third flight), C. Michael Foale (his fifth flight), John M. Grunsfeld (his third flight) and ESA astronaut Claude Nicollier (his fourth flight). This current video presents a live footage of the seven STS-103 crewmembers eating breakfast, suiting, and departing the O&C (Operations and Checkout) before the 6:50 p.m. lift-off.

  11. Introduction A l'Etude de la Médecine Expérimentale--surgical revolution part II.

    PubMed

    Toledo-Pereyra, Luis H

    2009-01-01

    The book that Claude Bernard (1813-1878) published in 1865, the Introduction à l'Etude de la Médecine Expérimentale, fostered a revolution that we believe influenced the practice of surgery when the discipline became a scientific enterprise. In Part I, we set the stage by presenting the life and accomplishments of Bernard, by reviewing his science, and introducing his experimental medicine work. In this issue in Part II, we further analyze his book and determine the "why" of a genuine surgical revolution. What were the factors that generated this revolution, and how a new generation of surgeons learned to become better researchers, and thus better surgeons, were the main objectives of this work. Science, research, and surgery became highly intertwined and the surgeon pursued these fields of knowledge more effectively.

  12. Let it burn: distinguishing inflammable airs 1766-1790.

    PubMed

    Tomory, Leslie

    2009-11-01

    The issue of the number of species of inflammable air was debated particularly in the period 1777-1786. The work of Henry Cavendish in 1766 and Alessandro Volta in 1777 in characterising two species of inflammable air set the stage for the work of other chemists, particularly in Paris, as they debated this question, mostly concerning heavy inflammable air. Different ways of generating gases were discovered up to 1783, when the synthesis of water and the proposal of carbon as an element created a framework for the question to be answered. In 1785-1786, Claude-Louis Berthollet reported the composition of heavy inflammable air and volatile alkali, while Philippe Gengembre analysed phosphorated hydrogen and hepatic air. In the end, it was the new chemical nomenclature of 1787 that spread their results widely.

  13. Whether weather affects music

    NASA Astrophysics Data System (ADS)

    Aplin, Karen L.; Williams, Paul D.

    2012-09-01

    The creative output of composers, writers, and artists is often influenced by their surroundings. To give a literary example, it has been claimed recently that some of the characters in Oliver Twist and A Christmas Carol were based on real-life people who lived near Charles Dickens in London [Richardson, 2012]. Of course, an important part of what we see and hear is not only the people with whom we interact but also our geophysical surroundings. Of all the geophysical phenomena to influence us, the weather is arguably the most significant because we are exposed to it directly and daily. The weather was a great source of inspiration for artists Claude Monet, John Constable, and William Turner, who are known for their scientifically accurate paintings of the skies [e.g., Baker and Thornes, 2006].

  14. STS-103 crew return at building 990, Ellington Field

    NASA Image and Video Library

    1999-12-29

    Photographic documentation showing STS-103 crew return at bldg. 990, Ellington Field. Views include: Mission Specialist (MS) John M. Grunsfeld at podium (16048); MS Jean-Francois Clervoy at podium (16049); Grunsfeld signs autographs (16050); woman and child (16051); MS Claude Nicollier meets his Swiss-American fan club (16052); Clervoy holds child (16053); mission commander Curtis L. Brown signs autographs (16054, 16057); MS E. Michael Foale signs autographs (16055); MS and Payload Commander (PLC) Steven L. Smith kneels and holds child (16056); overall view of stage showing Brown at podium with crew seated behind him; from left to right: Nicollier, pilot Scott J. Kelly, Clervoy, Grunsfeld, Mr. George Abbey (JSC director), Foale and Smith (16058); Nicollier at podium (16059); Mr. George Abbey at the podium (16060): Foale ath the podium (16061); Kelly signs autographs (16062).

  15. Information theory in systems biology. Part II: protein-protein interaction and signaling networks.

    PubMed

    Mousavian, Zaynab; Díaz, José; Masoudi-Nejad, Ali

    2016-03-01

    By the development of information theory in 1948 by Claude Shannon to address the problems in the field of data storage and data communication over (noisy) communication channel, it has been successfully applied in many other research areas such as bioinformatics and systems biology. In this manuscript, we attempt to review some of the existing literatures in systems biology, which are using the information theory measures in their calculations. As we have reviewed most of the existing information-theoretic methods in gene regulatory and metabolic networks in the first part of the review, so in the second part of our study, the application of information theory in other types of biological networks including protein-protein interaction and signaling networks will be surveyed. Copyright © 2015 Elsevier Ltd. All rights reserved.

  16. New Study Finds Increasing Gender Equity at U.S. Research Institutions

    NASA Astrophysics Data System (ADS)

    Showstack, Randy

    2009-06-01

    Women and men faculty in science, engineering, and mathematics for the most part have comparable opportunities within major U.S. research universities, according to a report released 2 June by the U.S. National Research Council (NRC). The report found that gender does not appear to have been a factor in a number of important career transitions and outcomes, including hiring for tenure track and tenure positions and promotions. “That is probably going to be surprising to many people. It was surprising to our own panel. And it may not have been the case if we had done the study in 1985 instead of 2005,” said Claude Canizares, cochair of the NRC committee that prepared the report, entitled Gender Differences at Critical Transitions in the Careers of Science, Engineering and Mathematics Faculty.

  17. Information Theory Applied to Animal Communication Systems and Its Possible Application to SETI

    NASA Astrophysics Data System (ADS)

    Hanser, Sean F.; Doyle, Laurance R.; McCowan, Brenda; Jenkins, Jon M.

    2004-06-01

    Information theory, as first introduced by Claude Shannon (Shannon &Weaver 1949) quantitatively evaluates the organizational complexity of communication systems. At the same time George Zipf was examining linguistic structure in a way that was mathematically similar to the components of the Shannon first-order entropy (Zipf 1949). Both Shannon's and Zipf's mathematical procedures have been applied to animal communication and recently have been providing insightful results. The Zipf plot is a useful tool for a first estimate of the characterization of a communication system's complexity (which can later be examined for complex structure at deeper levels using Shannon entropic analysis). In this paper we shall discuss some of the applications and pitfalls of using the Zipf distribution as a preliminary evaluator of the communication complexity of a signaling system.

  18. "The human use of human beings": Interdisciplinarity, transdisciplinarity and all that in biophysics and beyond.

    PubMed

    Tabacchi, Marco Elio; Termini, Settimo

    2017-10-01

    Biophysics, just by looking at its name, indicates an interdisciplinary scientific activity, although the notion of interdisciplinarity, as such, seems to be not widely or specifically discussed by biophysicists. The same seems to have happened as well in the early stages of the development of cybernetics, notably in Norbert Wiener's writings. This situation seems to contrast with what has happened in subsequent developments of cybernetics ideas, notably in general system theory and cognitive sciences. After a few general reflections on the notion of interdisciplinarity, its sophisticated variants and the path leading to the birth of cognitive science, we shall refer to Wiener's thought to extracts aspects and indications that could be useful today, also for what concerns the social responsibility of scientists, which could be seen as stemming from a very general form of interdisciplinarity. After a few general reflections on the notion of interdisciplinarity, its sophisticated variants and the path leading to the birth of cognitive science, we shall refer to Wiener's thought to extracts aspects and indications that could be useful today, also for what concerns the social responsibility of scientists. Copyright © 2017 Elsevier B.V. All rights reserved.

  19. Modulation theory, dispersive shock waves and Gerald Beresford Whitham

    NASA Astrophysics Data System (ADS)

    Minzoni, A. A.; Smyth, Noel F.

    2016-10-01

    Gerald Beresford (GB) Whitham, FRS, (13th December, 1927-26th January, 2014) was one of the leading applied mathematicians of the twentieth century whose work over forty years had a profound, formative impact on research on wave motion across a broad range of areas. Many of the ideas and techniques he developed have now become the standard tools used to analyse and understand wave motion, as the papers of this special issue of Physica D testify. Many of the techniques pioneered by GB Whitham have spread beyond wave propagation into other applied mathematics areas, such as reaction-diffusion, and even into theoretical physics and pure mathematics, in which Whitham modulation theory is an active area of research. GB Whitham's classic textbook Linear and Nonlinear Waves, published in 1974, is still the standard reference for the applied mathematics of wave motion. In honour of his scientific achievements, GB Whitham was elected a Fellow of the American Academy of Arts and Sciences in 1959 and a Fellow of the Royal Society in 1965. He was awarded the Norbert Wiener Prize for Applied Mathematics in 1980.

  20. Zeit im Wandel der Zeit.

    NASA Astrophysics Data System (ADS)

    Aichelburg, P. C.

    Contents: Einleitung(P. C. Aichelburg). 1. Über Zeit, Bewegung und Veränderung (Aristoteles). 2. Ewigkeit und Zeit (Plotin). 3. Was ist die Zeit? (Augustinus). 4. Von der Zeit (Immanuel Kant). 5. Newtons Ansichten über Zeit, Raum und Bewegung (Ernst Mach). 6. Über die mechanische Erklärung irreversibler Vorgänge (Ludwig Boltzmann). 7. Das Maß der Zeit (Henri Poincaré). 8. Dauer und Intuition (Henri Bergson). 9. Die Geschichte des Unendlichkeitsproblems (Bertrand Russell). 10. Raum und Zeit (Hermann Minkowski). 11. Der Unterschied von Zeit und Raum (Hans Reichenbach). 12. Newtonscher und Bergsonscher Zeitbegriff (Norbert Wiener). 13. Die Bildung des Zeitbegriffs beim Kinde (JeanPiaget).14. Eine Bemerkung über die Beziehungen zwischen Relativitätstheorie und der idealistischen Philosophie (Kurt Gödel). 15. Der zweite Hauptsatz und der Unterschied von Vergangenheit und Zukunft (Carl Friedrich v. Weizsäcker). 16. Zeit als physikalischer Begriff (Friedrich Hund). 17. Zeitmessung und Zeitbegriff in der Astronomie (Otto Heckmann). 18. Kann die Zeit rückwärts gehen? (Martin Gardner). 19. Zeit und Zeiten (Ilya Prigogine, Isabelle Stengers). 20. Zeit als dynamische Größe in der Relativitätstheorie (P. C. Aichelburg).

  1. Nurses' daily life: gender relations from the time spent in hospital.

    PubMed

    Pereira, Audrey Vidal

    2015-01-01

    to analyze the everyday life of nurses through the sexual work division as well as through interdependence relations and the time in hospital. quanti-qualitative study, based on the Time Use Survey and in Norbert Elias's Configuration Theory of Interdependencies. Daily shifts distribution record, directed by 42 participants--with self-confrontation--by interviews which drew dialogues on subjective aspects of the everyday experiences related to use of time, based on a job at a university hospital. The theoretical intake that founded data analysis was based on concepts of conflicts of interest, power struggles, sexual work division and polychronic-monochronic concepts--whether the work environment demands multitasking nurses or not. time records allowed to observe differences between the groups studied, useful to identify conflicts, tensions, power struggles and gender inequalities in interviewees' everyday affairs that do not only affect physical and mental health, but also their way of life. the analytical path pointed out the need for public policies that promote equity in gender relations, keeping at sight the exercise of plural discourses and tolerant stances capable to respect differences between individual and collective time.

  2. Quantum Error Correction: Optimal, Robust, or Adaptive? Or, Where is The Quantum Flyball Governor?

    NASA Astrophysics Data System (ADS)

    Kosut, Robert; Grace, Matthew

    2012-02-01

    In The Human Use of Human Beings: Cybernetics and Society (1950), Norbert Wiener introduces feedback control in this way: ``This control of a machine on the basis of its actual performance rather than its expected performance is known as feedback ... It is the function of control ... to produce a temporary and local reversal of the normal direction of entropy.'' The classic classroom example of feedback control is the all-mechanical flyball governor used by James Watt in the 18th century to regulate the speed of rotating steam engines. What is it that is so compelling about this apparatus? First, it is easy to understand how it regulates the speed of a rotating steam engine. Secondly, and perhaps more importantly, it is a part of the device itself. A naive observer would not distinguish this mechanical piece from all the rest. So it is natural to ask, where is the all-quantum device which is self regulating, ie, the Quantum Flyball Governor? Is the goal of quantum error correction (QEC) to design such a device? Devloping the computational and mathematical tools to design this device is the topic of this talk.

  3. Cosmic Perspectives

    NASA Astrophysics Data System (ADS)

    Biswas, S. K.; Mallik, D. C. V.; Vishveshwara, C. V.

    2008-07-01

    1. Astronomy in ancient and medieval China Joseph Needham; 2. Indian astronomy: an historical perspective B. V. Subbarayappa; 3. Making of astronomy in ancient India Debiprasad Chattopadhyaya; 4. The impact of astronomy on the development of western science Jean-Claude Pecker; 5. Man and the Universe Hubert Reeves; 6. Understanding the Universe - challenges and directions in modern observational astronomy Harlan Smith, Jr: 7. Frontiers in cosmology Fred Hoyle; 8. Did the Universe originate in a big bang? Jayant Narlikar; 9. The dark matter problem Bernard Carr; 10. Geometry and the Universe C. V. Vishveshwara; 11. The origin and evolution of life Cyril Ponnamperuma; 12. The anthropic principle: self selection as an adjunct to natural selection Brandon Carter; 13. Astrology and science: an examination of the evidence Ivan Kelly, Roger Culver and Peter Loptson; 14. Astronomy and science fiction Allen Janis.

  4. Mission Specialist Smith is suited and ready for launch

    NASA Technical Reports Server (NTRS)

    1999-01-01

    In the Operations and Checkout Building, STS-103 Mission Specialist Steven L. Smith signals he is suited up and ready for launch. Other crew members are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly and Mission Specialists C. Michel Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Jean-Frangois Clervoy of France and Claude Nicollier of Switzerland. Clervoy and Nicollier are with the European Space Agency. The STS-103 mission, to service the Hubble Space Telescope, is scheduled for launch Dec. 17 at 8:47 p.m. EST from Launch Pad 39B. Mission objectives include replacing gyroscopes and an old computer, installing another solid state recorder, and replacing damaged insulation in the telescope. After the 8-day, 21-hour mission, Discovery is expected to land at KSC Sunday, Dec. 26, at about 6:30 p.m. EST.

  5. STS-99 Endeavour rolls out to Launch Pad 39A

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Framed by branches of oak leaves in this photo, Space Shuttle Endeavour, on its mobile launcher platform, is transferred to Launch Pad 39B via the crawler-transporter. The van behind it is barely noticeable next to the gigantic stature of the moving vehicle. Launch of STS-103 is targeted for Dec. 16 at 9:18 p.m. EST. The crew, comprising Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland, with the European Space Agency (ESA), and Jean-Frangois Clervoy of France, also with ESA, will be servicing the Hubble Space Telescope, replacing gyros, insulation and equipment in up to three space walks. Landing is targeted for Dec. 26 about 6:56 p.m. at KSC's Shuttle Landing Facility.

  6. Use study of Excerpta Medica abstract journals: to drop or not to drop?

    PubMed Central

    Alligood, E C; Russo-Martin, E; Peterson, R A

    1983-01-01

    The directors of the Claude Moore Health Sciences Library, a medium-sized library serving the University of Virginia medical and nursing schools, were concerned over the increasing cost of periodical subscriptions and so studied the use of the printed copy of Excerpta Medica. This study had six parts: (1) availability in other campus libraries; (2) staff perceptions of in-library use; (3) results of studies performed by other libraries in the United States; (4) recorded in-library use; (5) users' opinions; and (6) personal interviews with library users and with selected departments tht corresponded with the forty-four subject areas of Excerpta Medica. The user-survey parts (4 and 5) elicited few responses, but personal interviews allowed a good look at levels of use and interest. The overall results convinced staff to drop some sections and publicize those that remained. PMID:6626797

  7. [History of the Montpellier Society of Biology].

    PubMed

    Bali, Jean-Pierre

    2017-01-01

    The provincial branch of Montpellier was officially created in April, 1956, that is to say if the gestation was long since the birth of the Society of Biology of Paris in 1848. During this long period, famous personalities of Montpellier in the field of biology and physiology came to Paris to present their work, published in the "Comptes Rendus des Séances de la Société de Biologie et de ses Filiales". Following its creation as a 1901 law public association, the provincial branch organized communication sessions, followed by thematic meetings on various topics, always in the spirit of Claude Bernard on the transversality of knowledge. Through the visit of a portrait gallery of famous personalities, the main lines of the life of this provincial branch of Montpellier will be presented. © Société de Biologie, 2017.

  8. Information theory in systems biology. Part I: Gene regulatory and metabolic networks.

    PubMed

    Mousavian, Zaynab; Kavousi, Kaveh; Masoudi-Nejad, Ali

    2016-03-01

    "A Mathematical Theory of Communication", was published in 1948 by Claude Shannon to establish a framework that is now known as information theory. In recent decades, information theory has gained much attention in the area of systems biology. The aim of this paper is to provide a systematic review of those contributions that have applied information theory in inferring or understanding of biological systems. Based on the type of system components and the interactions between them, we classify the biological systems into 4 main classes: gene regulatory, metabolic, protein-protein interaction and signaling networks. In the first part of this review, we attempt to introduce most of the existing studies on two types of biological networks, including gene regulatory and metabolic networks, which are founded on the concepts of information theory. Copyright © 2015 Elsevier Ltd. All rights reserved.

  9. STS-103 Mission Highlights Resource Tape (2 of 2)

    NASA Technical Reports Server (NTRS)

    2000-01-01

    The STS-103 flight crew, Commander Curtis L. Brown, Pilot Scott J. Kelly, Mission Specialists Steven L. Smith, C. Michael Foale, John M. Grunsfeld, Claude Nicollier, and Jean-Francois Clervoy, are seen passing over the Yucatan and Florida Peninsulas. Smith and Grunsfeld replace and change the S-band single transmission cables during the third and final space walk of this mission. Crewmembers are also seen taking video documentation of the solar arrays. Footage presented includes the release of the Hubble Space Telescope, thruster firing and orbit adjust burn over the Central Indian Ocean and Australia. Also shown is the night landing of Discovery at Kennedy Space Center, crew departure from the vehicle, and short statements made by the crew. This is tape 2 of 2; tape 1 has a report number of NONP-NASA-VT-2000036030.

  10. STS-103 Discovery reaches to Launch Pad 39B

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Space Shuttle Discovery approaches Launch Pad 39B where the orbiter, external tank and solid rocket boosters will undergo final preparations for the STS-103 launch. The mission is a 'call-up' due to the need to replace and repair portions of the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The STS-103 crew members are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), and Claude Nicollier of Switzerland and Jean-Frangois Clervoy of France, both with the European Space Agency. The mission is targeted for launch Dec. 6 at 2:37 a.m. EST.

  11. STS-103 Discovery reaches to Launch Pad 39B

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Space Shuttle Discovery arrives at Launch Pad 39B where the orbiter, external tank and solid rocket boosters will undergo final preparations for the STS-103 launch. The mission is a 'call-up' due to the need to replace and repair portions of the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The STS-103 crew members are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), and Claude Nicollier of Switzerland and Jean-Frangois Clervoy of France, both with the European Space Agency. The mission is targeted for launch Dec. 6 at 2:37 a.m. EST aboard Space Shuttle Discovery.

  12. Alpha List of Prime Contract Awards. Oct 92-Sep 93. FY93. (Claude Ralph - Day Francis O Co. Inc.)

    DTIC Science & Technology

    1994-03-01

    4LLAA ( LU AC x 0 m LA (LA 0 x1 (1A)LALLCA(A( AcCA L A 0 ( tALALA01upIc (00.- U1 C(0 (D0 (0’.CD(0 (D (D (D (DW 00 0 (m (m (0CD(D0(m0w(0(20 (D0w Lo(1(0...COVcII N 44444444444 4444444444 N c04 II 44 4444 N 0041 caoacao acca 0i 0o cn I’ ID6 OOCNY 2 N4NrJNNNNNN0 NNNNNNNNNN C3 cO-4 11 L) U0 0 0 0 0 0c 0 0 0 0...0.4 .. 14൰*o0oo 00 0 0 - .4 N 4j H 4 I0cc WOO 004 INN C 10 10 100N04144443(300 t0 I0.4 ffM MN 14 100 N 0YMIn C 0 0 (1 H ma I (fl>( IIO N N NN N 0 4

  13. Gregory Bateson and the mathematicians: from interdisciplinary interaction to societal functions.

    PubMed

    Heims, S P

    1977-04-01

    An instance of fruitful cross-disciplinary contacts is examined in detail. The ideas involved include (1) the double-blind hypothesis for schizophrenia, (2) the critique of game theory from the viewpoint of anthropology and psychiatry, and (3) the application of concepts of communication theory and theory of logical types to an interpretation of psychoanalytic practice. The protagonists of the interchange are Gregory Bateson and the two mathematicians Norbert Wiener and John von Neumann; the date, March 1946. This interchange and its sequels are described. While the interchanges between Bateson and Wiener were fruitful, those between Bateson and von Neumann were much less so. The latter two held conflicting premises concerning what is significant in science; Bateson's and Wiener's were compatible. In 1946, Wiener suggested that information and communication might be appropriate central concepts for psychoanalytic theory--a vague general idea which Bateson (with Ruesch) related to contemporary clinical practice. For Bateson, Wiener, and von Neumann, the cross-disciplinary interactions foreshadowed a shift in activities and new roles in society, to which the post World War II period was conducive. Von Neumann became a high-level government advisor; Wiener, an interpreter of science and technology for the general public; and Bateson a counter-culture figure.

  14. Chandra Adds to Story of the Way We Were

    NASA Astrophysics Data System (ADS)

    2003-05-01

    consisting of two pairs of stars, called HD 98800A and HD 98800B. These pairs, each of which is about an Earth-Sun distance apart, orbit each other at about the same distance as Pluto orbits the Sun. "Our X-ray results are fully consistent with other observations that show that accretion of matter from a disk in HD 98800A has dropped to a low level," said Kastner. "So Chandra has thrown new weight behind the evidence that any disk in this system has been greatly diminished or destroyed in ten million years, perhaps by the ongoing formation of planets or by the companion stars." The new X-ray technique for studying disks around stars relies on the ability of Chandra's spectrometers to measure the energies of individual X-rays very precisely. By comparing the number of X-rays emitted by hot gas at specific energies from ions such as oxygen and neon, the temperature and density of particles can be determined. This new technique will help astronomers to distinguish between an accretion disk and a stellar corona as the origin of intense X-ray emission from a young star. Other members of the research team are David Huenemoerder, Norbert Schulz, and Claude Canizares from the Massachusetts Institute of Technology, and David Weintraub from Vanderbilt University. NASA's Marshall Space Flight Center in Huntsville, Ala., manages the Chandra program, and TRW, Inc., Redondo Beach, Calif., is the prime contractor for the spacecraft. The Smithsonian's Chandra X-ray Center controls science and flight operations from Cambridge, Mass., for the Office of Space Science at NASA Headquarters, Washington. The image and additional information are available at: http://chandra.harvard.edu and http://chandra.nasa.gov

  15. Hearing Science in Mid-Eighteenth-Century Britain and France

    PubMed Central

    Gouk, Penelope; Sykes, Ingrid

    2011-01-01

    Benjamin Martin, the English natural philosopher, and Claude-Nicolas Le Cat, the French surgeon, both published important work on auditory physiology and function in the mid-eighteenth century. Despite their different backgrounds, there was consensus between the two scholars on key principles of hearing research, most notably the importance of the inner ear in relation to auditory perception. Martin's work (1755 [1763?]) drew directly on the surgical work of Le Cat (1741) to demonstrate the importance of the auditory mechanism in listening processes. Le Cat's interest in the ear, however, came in turn from his interest in surgical anatomy. Martin used Le Cat's elegant designs as a tool for the vivid communication of auditory function to a popular, fee-paying audience. The meeting of two very different minds through intellectual agreement and material transfer demonstrates the way in which principles of hearing science were established in the Enlightenment period. PMID:20634220

  16. Hearing science in mid-eighteenth-century Britain and France.

    PubMed

    Gouk, Penelope; Sykes, Ingrid

    2011-10-01

    Benjamin Martin, the English natural philosopher, and Claude-Nicolas Le Cat, the French surgeon, both published important work on auditory physiology and function in the mid-eighteenth century. Despite their different backgrounds, there was consensus between the two scholars on key principles of hearing research, most notably the importance of the inner ear in relation to auditory perception. Martin's work (1755 [1763?]) drew directly on the surgical work of Le Cat (1741) to demonstrate the importance of the auditory mechanism in listening processes. Le Cat's interest in the ear, however, came in turn from his interest in surgical anatomy. Martin used Le Cat's elegant designs as a tool for the vivid communication of auditory function to a popular, fee-paying audience. The meeting of two very different minds through intellectual agreement and material transfer demonstrates the way in which principles of hearing science were established in the Enlightenment period.

  17. The New Physics

    NASA Astrophysics Data System (ADS)

    Fraser, Gordon

    2006-04-01

    Introduction Gordon Fraser; Part I. Matter and the Universe: 1. Cosmology Wendy Freedman and Rocky Kolb; 2. Gravity Ronald Adler; 3. Astrophysics Arnon Dar; 4. Particles and the standard model Chris Quigg; 5. Superstrings Michael Green; Part II. Quantum Matter: 6. Atoms and photons Claude Cohen-Tannoudji and Jean Dalibard; 7. The quantum world of ultra-cold atoms Christopher Foot and William Phillips; 8. Superfluidity Henry Hall; 9. Quantum phase transitions Subir Sachdev; Part III. Quanta in Action: 10. Quantum entanglement Anton Zeilinger; 11. Quanta, ciphers and computers Artur Ekert; 12. Small-scale structure and nanoscience Yoseph Imry; Part IV. Calculation and Computation: 13. Nonlinearity Henry Abarbanel; 14. Complexity Antonio Politi; 15. Collaborative physics, e-science and the grid Tony Hey and Anne Trefethen; Part V. Science in Action: 16. Biophysics Cyrus Safinya; 17. Medical physics Nicolaj Pavel; 18. Physics and materials Robert Cahn; 19. Physics and society Ugo Amaldi.

  18. The New Physics

    NASA Astrophysics Data System (ADS)

    Fraser, Gordon

    2009-08-01

    Introduction Gordon Fraser; Part I. Matter and the Universe: 1. Cosmology Wendy Freedman and Rocky Kolb; 2. Gravity Ronald Adler; 3. Astrophysics Arnon Dar; 4. Particles and the standard model Chris Quigg; 5. Superstrings Michael Green; Part II. Quantum Matter: 6. Atoms and photons Claude Cohen-Tannoudji and Jean Dalibard; 7. The quantum world of ultra-cold atoms Christopher Foot and William Phillips; 8. Superfluidity Henry Hall; 9. Quantum phase transitions Subir Sachdev; Part III. Quanta in Action: 10. Quantum entanglement Anton Zeilinger; 11. Quanta, ciphers and computers Artur Ekert; 12. Small-scale structure and nanoscience Yoseph Imry; Part IV. Calculation and Computation: 13. Nonlinearity Henry Abarbanel; 14. Complexity Antonio Politi; 15. Collaborative physics, e-science and the grid Tony Hey and Anne Trefethen; Part V. Science in Action: 16. Biophysics Cyrus Safinya; 17. Medical physics Nicolaj Pavel; 18. Physics and materials Robert Cahn; 19. Physics and society Ugo Amaldi.

  19. Obesity and Gestational Diabetes Mellitus Pathways for Programming in Mouse, Monkey, and Man—Where Do We Go Next? The 2014 Norbert Freinkel Award Lecture

    PubMed Central

    2015-01-01

    Obesity and gestational diabetes mellitus continue to increase worldwide and span the spectrum of age, race, ethnicity, and socioeconomic status. Alarmingly, 1 in 10 infants and toddlers is obese, and 1 in 5 youths is both obese and at risk for metabolic syndrome prior to puberty. The mechanisms underlying how poor maternal health imparts risk for future metabolic disease in the offspring are beginning to emerge in deeply phenotyped human and nonhuman primate models. Maternal diet and obesity impact fuels, hormones, and inflammation with powerful effects on fetal metabolic systems. These are accompanied by persistent changes in the infant microbiome and epigenome and in offspring behavior. These results suggest that gestational and lactational dietary exposures are driving health risks in the next generation. Whether maternal diet can prevent changes in the womb to alter infant life-course disease risk is still unknown. Controlled, mechanistic studies to identify interventions are sorely needed for a healthier next generation. PMID:26207051

  20. MO-FG-213-04: Managing the Relationship

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wong, J.

    and Research Contracts – a Primer [Norbert Pelc; Stanford University] What topics are suited to industrial grants vs. academic grants How do resources (personnel effort, tuition) get allocated and charged in academia What are reasonable resource and timeline requests for small and big projects; from small and big companies “Fair market value” considerations Sections of a research agreement (IP including software confidential information, publications, data, exclusivity, support) 4. Managing the relationship [John Wong, Johns Hopkins University] How to effectively collaborate with each other How to adapt to changes in the relationship How to renew funding with the industry Moderated Panel Discussion [All speakers + moderators] Learning Objectives: 1. Understand the motivations of each partner 2. Elements that contribute to a successful partnership 3. Avoiding pitfalls - Challenges on either side that may derail a project 4. How to frame a research grant and agreement 5. How to sustain the collaborative relationship Amit Sawant: Funding from: NIH. Varian, Elekta and VisionRT; Michelle Svatos: Employee and shareholder: Varian, Board Member, TopasMC; Kevin Brown: Employee, Elekta; T. Rock Mackie: Consultant, Accuray; Norbert Pelc: Research support: Philips Healthcare, GE Healthcare; John Wong: Funding from NIH, Xstrahl and Elekta. Co-founder and advisor for JPLC Associates, LLC.« less

  1. Using cosmogenic nuclides to date the stabilisation age of relict rockglaciers

    NASA Astrophysics Data System (ADS)

    Kronig, Olivia; Reitner, Jürgen M.; Christl, Marcus; Ivy-Ochs, Susan

    2017-04-01

    Active rockglaciers are periglacial landforms which are creeping down mountain slopes due to plastic deformation of the interstitial ice. The occurrence of active rockglaciers is an indicator of Alpine permafrost. Relict rockglaciers are not moving anymore because the ice melted, but they give evidence for the earlier existence of permafrost. In the Alps, relict rockglaciers can often be found below today's tree line raising the question of when these landforms have last been active. Judging from the present position of the relict rockglaciers, the lower permafrost limit during the time of their activity must have been hundreds of meters lower than it is today. Already in the early days of rockglacier research, the potential of relict rockglaciers as a paleoclimate proxy was recognised (Barsch 1977, Haeberli 1985). However, obtaining absolute ages on relict rockglaciers has always been a major difficulty. Lately it has been shown that with cosmogenic nuclides it is possible to date the stabilisation age of relict rockglaciers, but it has been applied only in a few cases (Ivy-Ochs et al. 2009). According to Reitner (2007), the lowest relict rockglaciers of the eastern Alps, the Tandl rockglaciers, are located in the Province of Carinthia (Austria). The Tandl rockglaciers are a complex series of rockglaciers spanning from around 2300 m down to 1220 m a.s.l. Due to their low position and based on modelling estimates on permafrost distribution in the area (Avian & Kellerer-Pirklbauer 2012), it is plausible that these low rockglaciers were active even prior to the Younger Dryas. Therefore, samples from the entire rockglacier series were taken for 10Be exposure dating. Furthermore, the close proximity of the rockglaciers to moraines associated to the Gschnitz stadial allow comparing the dating results to equilibrium line depression reconstructions. Less than 10 km to the southwest, a second rockglacier series, the Norbert rockglaciers, was sampled. In contrast to the

  2. Bruner's Search for Meaning: A Conversation between Psychology and Anthropology

    PubMed Central

    Mattingly, Cheryl; Lutkehaus, Nancy C.; Throop, C. Jason

    2010-01-01

    We introduce a special issue of Ethos devoted to the work of Jerome Bruner and his careerlong attempts to seek innovative ways to foster a dialogue between psychology and anthropology. The articles in this special issue situate Bruner's meaning-centered approach to psychology and his groundbreaking work on narrative in the broader context of the developmental trajectory of both of fields of inquiry. Bruner's work has been enormously influential in the subfields of cultural psychology and psychological anthropology, especially because of his important contributions to our understanding of the intimate relationship between culture and mind. We examine Bruner's past and ongoing engagement with such luminary figures as Lev Vygotsky, Jean Piaget, Alfred Kroeber, Claude Lévi-Strauss, and Clifford Geertz to highlight points of convergence and tension between his version of cultural psychology and contemporary theorizing and practice in psychological anthropology. We also review his practical and theoretical contributions to the fields of medicine, law, and education. PMID:20706551

  3. [Agustín Moreno: scientific psychology and women's legal responsibility in Spain].

    PubMed

    Bandrés, Javier; Llavona, Rafael

    2011-11-01

    Agustín Moreno Rodríguez (1886-1967) studied Medicine and Natural Sciences at the Central University of Spain, in Madrid. He was a student of Dr. Luis Simarro, the University's professor of Experimental Psychology and of Tomas Maestre, the University's professor of Medical Law, Toxicology and Psychiatry. In 1910, he published the text The woman's civil and penal responsibility during the menstrual period. In this work, he approaches the question of the legal responsibility of women, based on the principle of excitation/reaction of Claude Bernard and on his personal version of the concept of iteration elaborated by Luis Simarro. Dr. Moreno also defends the thesis that menstruation adds some uniqueness to the function of the feminine psyche and, therefore, modifies the responsibility of a woman's actions. We also comment on the predominant approach to the mind of women in the Spanish scientific psychology of that time and the reaction of the Spanish feminist intellectuals.

  4. Minding experience: An exploration of the concept of "experience" in the early French anthropology of Durkheim, Lévy-Bruhl, and Lévi-Strauss.

    PubMed

    Throop, C Jason

    2003-01-01

    In line with the growing concern with the unexamined reliance upon the concept of "experience" in anthropology, this article explores in some detail the various usages and definitions of the concept in the work of three of early French anthropology's most influential theorists: Emile Durkheim (1858-1918), Lucien Lévy-Bruhl (1857-1939), and Claude Lévi-Strauss (1908-). With its important influence on both British and American anthropology, the early French anthropological tradition, as epitomized in the writings of these three thinkers, has indeed played a pivotal role in shaping many current taken-for-granted understandings of the concept of experience in the discipline of anthropology as a whole. In the process of exploring how experience is viewed by these three scholars, this paper will thus take some initial steps toward the historical contextualization of many of the unquestioned assumptions underpinning current understandings of experience in the discipline of anthropology and the social sciences more generally. Copyright 2003 Wiley Periodicals, Inc.

  5. Disaster mythology and fact: Hurricane Katrina and social attachment.

    PubMed

    Jacob, Binu; Mawson, Anthony R; Payton, Marinelle; Guignard, John C

    2008-01-01

    Misconceptions about disasters and their social and health consequences remain prevalent despite considerable research evidence to the contrary. Eight such myths and their factual counterparts were reviewed in a classic report on the public health impact of disasters by Claude de Ville de Goyet entitled, The Role of WHO in Disaster Management: Relief, Rehabilitation, and Reconstruction (Geneva, World Health Organization, 1991), and two additional myths and facts were added by Pan American Health Organization. In this article, we reconsider these myths and facts in relation to Hurricane Katrina, with particular emphasis on psychosocial needs and behaviors, based on data gleaned from scientific sources as well as printed and electronic media reports. The review suggests that preparedness plans for disasters involving forced mass evacuation and resettlement should place a high priority on keeping families together--and even entire neighborhoods, where possible--so as to preserve the familiar and thereby minimize the adverse effects of separation and major dislocation on mental and physical health.

  6. [Influence of disease on Matisse and Monet painting].

    PubMed

    Castillo-Ojugas, Antonio

    2003-01-01

    Henri Matisse (1869-1954) "Fauvisme", radically changed as for 1941, when he endured a severe surgery due to intestinal cancer. The resulting wound got necrosis, leading to a deficit at his abdominal muscles that impeached him to remain standing and paint. Sitting on his wheelchair, he started to cut out pieces of papers with which we created artistic collages. He died in 1954, aged 84, almost 13 years after his surgery. Claude Monet (1840-1926). After a journey to Venice in 1908, when he was 68 years old, cataracts were detected in Monet's both eyes, leading to the loss of his sight on his left eye and to an abnormal perception of colours on his right one. These alterations can be detected at his pieces of work. The surgery on his right eye en 1923, evoluted to a rare complication, know as "Xantopsia", that is, yellow-coloured sight, which was partially corrected through "Zeiss" linses. He died on lung cancer on 5th December 1926, aged 86.

  7. The history of stress hyperglycaemia.

    PubMed

    Balasanthiran, A; Shotliff, K

    2015-01-01

    Stress hyperglycaemia, is a common phenomenon, frequently associated with adverse outcomes in a number of prevalent conditions including myocardial infarction and stroke. Knowledge on stress hyperglycaemia evolved in tandem with knowledge relating to homeostasis, stress and disease and involved some of the world's most eminent thinkers. Despite this, it still remains under-recognised. This paper illustrates significant points in the history of stress hyperglycaemia, from antiquity through to the present day, as well as the challenges faced in translating research into clinical benefit for patients. Profiles of significant protagonists including Claude Bernard, Walter Cannon and Hans Seyle are presented, as well their roles in the emergence of modern-day terminology and pathophysiological models. Major themes such as 'fight or flight' and homeostasis are central to this discussion. Closer to the present day, the role of stress hyperglycaemia in a number of common medical conditions is explored in more detail. Contention around evidence for treatment and the future risk of diabetes mellitus are also discussed.

  8. STS-103 Mission Specialist Smith suits up before launch

    NASA Technical Reports Server (NTRS)

    1999-01-01

    After donning his launch and entry suit, sts-103 Mission Specialist Steven L. Smith shows a positive attitude over the second launch attempt for Space Shuttle Discovery. The previous launch attempt on Dec. 17 was scrubbed about 8:52 p.m. due to numerous violations of weather launch commit criteria at KSC. Smith and other crew members Commander Curtis L. Brown Jr., Pilot Scott J. Kelly and Mission Specialists C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland and Jean-Francois Clervoy of France are scheduled to lift off at 7:50 p.m. EST Dec. 19 on mission STS-103, servicing the Hubble Space Telescope. Objectives for the nearly eight-day mission include replacing gyroscopes and an old computer, installing another solid state recorder, and replacing damaged insulation in the telescope. Discovery is expected to land at KSC Monday, Dec. 27, at about 5:24 p.m. EST.

  9. [The three lives of the Count de Bonneval, alias Osman Pasha (1675-1747)].

    PubMed

    Fabre, André-Julien

    2008-12-01

    Count Claude-Alexandre de Bonneval (1675-1747), had a unusual existence: he had three consecutive lives: as an Officer in the Royal Guard of Louis XIV, as Major-General with Prince Emmanuel of Savoy and, finally, as Ottoman Pasha in Constantinople. He was a man of multiple facets: soldier and political adviser, swordsman and world traveller, friend of Casanova, Fenelon, Montesquieu and Leibniz. He was also an inveterate transgressor of every rule and, in the end, a renegade apostate. Many explanations have been offered for his astounding life: plain aristocratic frivolity, emotional instability, and possibly, in reference to a permanent quest for new adventures, countries or religions, a touch of transformism. Obviously, Bonneval concealed, behind a flamboyant personality, some sort of psychiatric fragility which might suggest, in retrospect, a "paranoid syndrome" but, certainly, no trace of what is common in psychopathic patients, a weariness of life. Bonneval loved each one of his three lives and the feeling was mutual.

  10. [THE SCIENTIFIC REVOLUTION IN MEDICINE OF THE LAST QUARTER OF XIX-FIRST HALF OF XX CENTURIES. REPORT II. THE OUTSET OF REVISION OF MEDICAL SCIENCE].

    PubMed

    Stochik, A M; Zatravkin, S N

    2015-01-01

    The article affirms that onset of revision of picture of analyzed reality, methodological approaches to studying of vital activity of human organism and philosophical basics of medical science refers to 1878 and is related to publishing of "The course of general physiology" by French physiologist Claude Bernard. The implemented analysis of the text of this work permit to establish that C. Bernard undertook an attempt to introduce conception of human organism as a processing system being self-reproduced as. a result of interaction with environment due to mechanisms of self-regulation. The necessity was substantiated to make experiment the leading method of cognition of vital activity. The living wholeness (organism, cell) was proposed to be an object of experimentation. In this living wholeness its natural capacities to self-regulation of main vital processes can be preserved at its maximum. The new senses were introduced into ontological categories of thing, process, causality, portion and whole.

  11. Introduction à L'Etude de la Médecine Expérimentale. Surgical revolution. Part I.

    PubMed

    Toledo-Pereyra, Luis H

    2009-01-01

    Claude Bernard (1813-1878), the most distinguished French physiologist of the 19th century, made incomparable contributions to the world of medicine of his times and even to ours. Bernard believed in scientific determinism and created the term milieu interieur as a manner to better understand experimental medicine and to present a new way of explaining the function of the living organism. Bernard dealt with innovative developments in the glycogenetic function of the liver, extrahepatic glycogenesis, the role of pancreatic juice in the digestion of fats, vasomotor nervous system discoveries, and other important physiological advances. In 1865, Bernard's most extraordinary book on the philosophy and understanding of experimental medicine appeared. This book represented Bernard's unique contribution to the progress of medical and surgical research. Because of the enormous implications of this work on the advancement of surgical research, which were subsequently applied to clinical surgical practice, we propose that this book created a surgical revolution.

  12. Beautiful Surfaces. Style and Substance in Florentius Schuyl's Illustrations for Descartes' Treatise on Man.

    PubMed

    Chan, Eleanor

    2016-01-01

    The assumption that the Cartesian bête-machine is the invention of René Descartes (1596-1650) is rarely contested. Close examination of Descartes' texts proves that this is a concept founded not on the basis of his own writings, but a subsequent critical interpretation, which developed and began to dominate his work after his death. Descartes' Treatise on Man, published posthumously in two rival editions, Florentius Schuyl's Latin translation De Homine (1662), and Claude Clerselier's Traité de l'homme, has proved particularly problematic. The surviving manuscript copies of the Treatise on Man left no illustrations, leaving both editors the daunting task of producing a set of images to accompany and clarify the fragmented text. In this intriguing case, the images can be seen to have spoken louder than the text which they illustrated. This paper assesses Schuyl's choice to represent Descartes' Man in a highly stylized manner, without superimposing Clerselier's intentions onto De Homine.

  13. [Adélaïde Hautval (1906-1988): An exemplary medical personality].

    PubMed

    Halioua, Bruno; Hauptmann, Georges

    2015-12-01

    Adélaïde Hautval (1906-1988), psychiatrist, was arrested in April 1942 having defended a Jewish family abused by German soldiers. She was imprisoned in Bourges and in several camps in France (Pithiviers, Beaune-la-Rolande, Orléans, Romainville) before being deported as a "Friend of the Jews" at Auschwitz in the convoy of 23 January 1943, said 31,000 convoy with 229 other resistant women, Marie-Claude Vaillant-Couturier, Charlotte Delbo, Danielle Casanova. She refused to participate in the "medical" experience of Nazi doctors Clauberg, Schumann, Wirths and Mengele at Birkenau. She was then deported to Ravensbrück. During her deportation, she illustrated her dedication in the medical management of the deportees. She testified repeatedly on her experience of remote doctor. Hautval Adélaïde was the first French woman doctor named Righteous among the Nations in 1965. Copyright © 2015 Elsevier Masson SAS. All rights reserved.

  14. STS-61 crew utilizing Virtual Reality in training for HST repair mission

    NASA Technical Reports Server (NTRS)

    1993-01-01

    Astronaut Jeffrey A. Hoffman, one of four crewmembers for STS-61 that will conduct scheduled spacewalks during the flight, wears a special helmet and gloves designed to assist in proper positioning near the telescope while on the end of the robot arm. Crewmembers are utilizing a new virtual reality training aid which assists in refining positioning patterns for Space Shuttle Endeavour's Remote Manipulator System (RMS) (36890); Astronaut Claude Nicollier looks at a computer display of the Shuttle's robot arm movements as Thomas D. Akers and Kathryn C. Thornton, mission specialists look on. Nicollier will be responsible for maneuvering the astronauts while they stand in a foot restraint on the end of the RMS arm (36891,36894); Hoffman wears a special helmet and gloves designed to assist in proper positioning near the telescope while on the end of the robot arm (35892); Nicollier looks at a computer display of the Shuttle's robot arm movements as Akers looks on (36893); While (l-r) Astron

  15. Mendelevium: The Way It Was

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None

    A reel of black & white film shot nearly 60 years ago has surfaced at Berkeley Lab, depicting the discovery of Mendelevium - or Element 101 - as reenacted by some of the legendary scientists who did the actual work at that time. Since the 1940s, Berkeley Lab scientists were locked in a race to synthesize new elements, and more often than not, they came out winners. Sixteen elements, most of them in the actinide series at the bottom of the periodic table, were discovered and synthesized by its researchers. Retired Berkeley Lab physicist Claude Lyneis found the reel inmore » a box of dusty and deteriorating films slated for disposal. Using digital editing skills he acquired to make videos of his son's lacrosse team, Lyneis has produced and narrated an excerpt of this nearly-lost footage. It is an entertaining and informative look at the pioneering physics performed at UC Berkeley and Lawrence Berkeley National Laboratory's hillside campus.« less

  16. [Dietary modernity and food consumption: socio-anthropological contributions to research in nutrition].

    PubMed

    Fonseca, Alexandre Brasil; de Souza, Thaís Salema Nogueira; Frozi, Daniela Sanches; Pereira, Rosangela Alves

    2011-09-01

    The scope of this work was to illustrate what dietary modernity represents for sociology and anthropology, which is a subject based on a bibliographic review that is discussed in this article. Initially, the presence of the theme of food and nutrition was assessed in studies in the social sciences, by focusing on the approaches related to dietary modernity, especially as found in the works of Claude Fischler. The main subjects of discussion were related to food and nutrition and changes in the work environment, the expansion of commerce, the feminization of society and the question of identity. By understanding the food phenomenon and consumption thereof using a more qualitative approach, it is possible to make progress in configuring the nutritional sciences, adopting a comprehensive approach to food and nutrition in this day and age. Future studies should be dedicated to investigating food consumption as a social phenomenon in order to aggregate new analytical components with a biomedical emphasis to the body of results.

  17. Integrated design of cryogenic refrigerator and liquid-nitrogen circulation loop for HTS cable

    NASA Astrophysics Data System (ADS)

    Chang, Ho-Myung; Ryu, Ki Nam; Yang, Hyung Suk

    2016-12-01

    A new concept of cryogenic cooling system is proposed and investigated for application to long-length HTS cables. One of major obstacles to the cable length of 1 km or longer is the difficulty in circulating liquid nitrogen (LN) along the cables, since the temperature rise and pressure drop of LN flow could be excessively large. This study attempts a breakthrough by integrating the refrigerator with the LN circulation loop in order to eliminate the cryogenic LN pumps, and generate a large LN flow with the power of compressors at ambient temperature. A variety of thermodynamic structures are investigated on standard and modified Claude cycles, where nitrogen is used as refrigerant and the LN circulation loop is included as part of the closed cycle. Four proposed cycles are fully analyzed and optimized with a process simulator (Aspen HYSYS) to evaluate the FOM (figure of merit) and examine the feasibility. The modified dual-pressure cycle cooled with expander stream is recommended for long HTS cables.

  18. Hypothalamic neurones governing glucose homeostasis.

    PubMed

    Coppari, R

    2015-06-01

    The notion that the brain directly controls the level of glucose in the blood (glycaemia) independent of its known action on food intake and body weight has been known ever since 1849. That year, the French physiologist Dr Claude Bernard reported that physical puncture of the floor of the fourth cerebral ventricle rapidly leads to an increased level of sugar in the blood (and urine) in rabbits. Despite this important discovery, it took approximately 150 years before significant efforts aimed at understanding the underlying mechanism of brain-mediated control of glucose metabolism were made. Technological developments allowing for genetically-mediated manipulation of selected molecular pathways in a neurone-type-specific fashion unravelled the importance of specific molecules in specific neuronal populations. These neuronal pathways govern glucose metabolism in the presence and even in the absence of insulin. Also, a peculiarity of these pathways is that certain biochemically-defined neurones govern glucose metabolism in a tissue-specific fashion. © 2015 British Society for Neuroendocrinology.

  19. Mendelevium: The Way It Was

    ScienceCinema

    None

    2018-05-30

    A reel of black & white film shot nearly 60 years ago has surfaced at Berkeley Lab, depicting the discovery of Mendelevium - or Element 101 - as reenacted by some of the legendary scientists who did the actual work at that time. Since the 1940s, Berkeley Lab scientists were locked in a race to synthesize new elements, and more often than not, they came out winners. Sixteen elements, most of them in the actinide series at the bottom of the periodic table, were discovered and synthesized by its researchers. Retired Berkeley Lab physicist Claude Lyneis found the reel in a box of dusty and deteriorating films slated for disposal. Using digital editing skills he acquired to make videos of his son's lacrosse team, Lyneis has produced and narrated an excerpt of this nearly-lost footage. It is an entertaining and informative look at the pioneering physics performed at UC Berkeley and Lawrence Berkeley National Laboratory's hillside campus.

  20. Environment Eu agrees on cut in greenhouse gases

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    1997-03-12

    In an unexpected development, the European Union`s (EU) Council of Environment Ministers has agreed to a 2010 deadline for a 15% reduction in emissions of greenhouse gases. The agreement outlines the European Commission`s strategy for the reduction of greenhouse gases, including carbon dioxide (CO{sub 2}), to be negotiated in the UN conference on climate change to be held in Kyoto, Japan in December (CW, Feb. 26, p. 8). The European Chemical Industry Council (Cefic) says the commission`s target could curb competitiveness and even lead to the closure of some plants. {open_quotes}It`s certainly a target that is unrealistic--2010 is too close.more » Industry needs more time to adjust, assuming that it can at all,{close_quotes} Cefic environment counselor Claude Culem tells CW. {open_quotes}It [is] obviously a unilateral decision [made] by the commission with little [consideration] for industry.{close_quotes}« less

  1. The STS-103 crew address family and friends at Pad 39B

    NASA Technical Reports Server (NTRS)

    1999-01-01

    The STS-103 crew address family and friends at Launch Pad 39B. From left to right are Pilot Scott J. Kelly, Commander Curtis L. Brown Jr., and Mission Specialists C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Jean-Frangois Clervoy of France , Claude Nicollier of Switzerland and Steven L. Smith. Nicollier and Clervoy are with the European Space Agency. In the background is Space Shuttle Discovery, alongside the lighted Fixed Service Structure. The STS-103 mission, to service the Hubble Space Telescope, is scheduled for launch Dec. 17 at 8:47 p.m. EST from Launch Pad 39B. Mission objectives include replacing gyroscopes and an old computer, installing another solid state recorder, and replacing damaged insulation in the telescope. The mission is expected to last about 8 days and 21 hours. Discovery is expected to land at KSC Sunday, Dec. 26, at about 6:25 p.m. EST.

  2. Development and performance evaluation of high speed cryogenic turboexpanders at BARC, India

    NASA Astrophysics Data System (ADS)

    Chakravarty, A.; Menon, R. S.; Goyal, M.; Ahmed, N.; Jadhav, M.; Rane, T.; Nair, S. R.; Kumar, J.; Kumar, N.; Bharti, S. K.; Jain, A.; Joemon, V.

    2017-12-01

    Turboexpanders are a key focus area for Bhabha Atomic Research Centre (BARC), Mumbai, India in the program for development of helium refrigerators and liquefiers for intra departmental requirements. To start with, a turbine impeller with major diameter 16 mm and design speed of 264,000 RPM, suited for use in the 1st stage of a modified Claude cycle/reverse Brayton cycle based standard helium liquefier/refrigerator, is developed. Later on, a second series of turboexpander with the same major diameter (16 mm) and design speed of 260,000 RPM is developed with “splitter” blades at the major diameter end. Yet another turboexpander series, size 16.5 mm and design speed 168,000 RPM, is also developed suited for use in the 2nd stage of a standard helium liquefier/refrigerator. The present article describes these turboexpander development efforts at BARC, including results obtained during field trials with the BARC helium refrigerator and liquefier.

  3. STS-103 Discovery crawls to Launch Pad 39B

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Space Shuttle Discovery makes the turn toward Launch Pad 39B on its 4.2-mile (6.8 kilometer) trek atop the mobile launcher platform and crawler transporter. Once at the pad, the orbiter, external tank and solid rocket boosters will undergo final preparations for the STS-103 launch targeted for Dec. 6, 1999, at 2:37 a.m. EST. The mission is a 'call-up' due to the need to replace and repair portions of the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The STS-103 crew members are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), and Claude Nicollier of Switzerland and Jean-Frangois Clervoy of France, both with the European Space Agency.

  4. STS-103 Discovery reaches to Launch Pad 39B

    NASA Technical Reports Server (NTRS)

    1999-01-01

    At Launch Pad 39B, Space Shuttle Discovery towers against the hazy blue sky after a seven-hour trek from the Vehicle Assembly Building. The orbiter, external tank and solid rocket boosters will undergo final preparations for the STS-103 launch. The mission is a 'call-up' due to the need to replace and repair portions of the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The STS-103 crew members are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), and Claude Nicollier of Switzerland and Jean-Frangois Clervoy of France, both with the European Space Agency. The mission is targeted for launch Dec. 6 at 2:37 a.m. EST.

  5. STS-103 Discovery crawls to Launch Pad 39B

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Space Shuttle Discovery stands poised in the open door of the Vehicle Assembly Building before its 4.2-mile (6.8 kilometer) crawl to Launch Pad 39B atop the mobile launcher platform and crawler transporter. Once at the pad, the orbiter, external tank and solid rocket boosters will undergo final preparations for the STS-103 launch targeted for Dec. 6, 1999, at 2:37 a.m. EST. The mission is a 'call-up' due to the need to replace and repair portions of the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The STS-103 crew members are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), and Claude Nicollier of Switzerland and Jean-Frangois Clervoy of France, both with the European Space Agency.

  6. STS-103 Discovery crawls to Launch Pad 39B

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Space Shuttle Discovery clears the Vehicle Assembly Building (left) on its 4.2-mile (6.8 kilometer) crawl to Launch Pad 39B atop the mobile launcher platform and crawler transporter. Once at the pad, the orbiter, external tank and solid rocket boosters will undergo final preparations for the STS-103 launch targeted for Dec. 6, 1999, at 2:37 a.m. EST. The mission is a 'call-up' due to the need to replace and repair portions of the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The STS-103 crew members are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), and Claude Nicollier of Switzerland and Jean-Frangois Clervoy of France, both with the European Space Agency.

  7. British Muslims and the UK government's 'war on terror' within: evidence of a clash of civilizations or emergent de-civilizing processes?

    PubMed

    Vertigans, Stephen

    2010-03-01

    In the immediate aftermath of the September 2001 attacks on America, defending civilization was quickly established at the core of the 'war on terror'. Unintentionally or otherwise this incorporation of civilization connected with Samuel Huntington's 'Clash of Civilizations' thesis. Within the 'war on terror' the dark side of counterterrorism has become apparent through international practices like extrajudicial killing, extraordinary rendition and torture. The impact of Western governments' policies upon their indigenous Muslim populations has also been problematic but social and political analysis has been relatively limited. This paper seeks to help address the scarcity of sociological contributions. Hidden costs of the UK government's attempts to utilize violence and enhance social constraints within the nation-state are identified. It is argued that although counterterrorism strategies are contributing to a self-fulfilling spiral of hatred that could be considered evidence in support of the 'Clash of Civilizations', the thesis is unhelpful when trying to grasp the underlying processes. Instead the paper draws upon Norbert Elias's application of the concepts of 'civilizing' and 'de-civilizing' to help improve levels of understanding about the processes and consequences of particular Muslim communities being targeted by security forces. The paper concludes with an exploration of the majority of the population's acquiescence and willingness to accept restraints upon Muslims in order to safeguard their own security.

  8. Transcending disciplines: Scientific styles in studies of the brain in mid-twentieth century America.

    PubMed

    Abraham, Tara H

    2012-06-01

    Much scholarship in the history of cybernetics has focused on the far-reaching cultural dimensions of the movement. What has garnered less attention are efforts by cyberneticians such as Warren McCulloch and Norbert Wiener to transform scientific practice in an array of disciplines in the biomedical sciences, and the complex ways these efforts were received by members of traditional disciplines. In a quest for scientific unity that had a decidedly imperialistic flavour, cyberneticians sought to apply practices common in the exact sciences-mainly theoretical modeling-to problems in disciplines that were traditionally defined by highly empirical practices, such as neurophysiology and neuroanatomy. Their efforts were met with mixed, often critical responses. This paper attempts to make sense of such dynamics by exploring the notion of a scientific style and its usefulness in accounting for the contrasts in scientific practice in brain research and in cybernetics during the 1940s. Focusing on two key institutional contexts of brain research and the role of the Rockefeller and Macy Foundations in directing brain research and cybernetics, the paper argues that the conflicts between these fields were not simply about experiment vs. theory but turned more closely on the questions that defined each area and the language used to elaborate answers. Copyright © 2012 Elsevier Ltd. All rights reserved.

  9. Diurnal behaviour of some salivary parameters in patients with diabetes mellitus (flow rate, pH, thiocianat, LDH activity)--note II.

    PubMed

    Ionescu, S; Bădiţă, D; Artino, M; Dragomir, M; Huidovici, E; Niţă, V; Chiţoi, E

    1998-01-01

    The study was performed on 31 diabetic patients of both sexes, divided in 2 groups: group I--17 patients with insulin-dependent diabetes (IDDM) and group II--14 patients with noninsulin-dependent diabetes (NIDDM) and compared with a control group of 16 non-diabetic subjects. Mixed saliva was sampled without stimulation during 2 periods of the day: 07:30-08:00 before breakfast and 17:30-18:00 before dinner. We determined: salivary flow rate, pH with Merck indicator and, after homogenization, the thiocianat with the FeCl3 method and LDH activity (the Norbert method adapted in our laboratory for saliva). Our study showed the same diurnal changes in flow rate and salivary pH in both diabetic and control groups: minimal values in the morning and maximal ones in the afternoon. In non-smoking diabetic patients the salivary thiocianat had maximal values in the morning and minimal ones in the afternoon; similar behaviour, but less obvious was observed in smoking diabetic patients and in the control group regardless of the smoking habit. LDH activity showed unsignificant diurnal variations in the diabetic patients. In the control group we found a significant decrease of LDH activity in the afternoon. The discussion is about the implication of these salivary parameters in the pathology of oral cavity: gingivitis, periodontitis and caries in diabetic patients.

  10. Reply to comment by Claude Michel on "A general power equation for predicting bed load transport rates in gravel bed rivers"

    Treesearch

    Jeffrey J. Barry; John M. Buffington; John G. King

    2005-01-01

    We thank Michel [2005] for the opportunity to improve our bed load transport equation [Barry et al., 2004, equation (6)] and to resolve the dimensional complexity that he identified. However, we do not believe that the alternative bed load transport equation proposed by Michel [2005] provides either the mechanistic insight or predictive power of our transport equation...

  11. Validating Reference Equations for Impulse Oscillometry in Healthy Mexican Children.

    PubMed

    Gochicoa-Rangel, Laura; Del Río-Hidalgo, Rodrigo; Hernández-Ruiz, Juana; Rodríguez-Moreno, Luis; Martínez-Briseño, David; Mora-Romero, Uri; Cid-Juárez, Silvia; García-Sancho, Cecilia; Torre-Bouscoulet, Luis

    2017-09-01

    The impulse oscillometry system (IOS) measures the impedance (Z) of the respiratory system, but proper interpretation of its results requires adequate reference values. The objectives of this work were: (1) to validate the reference equations for the IOS published previously by our group and (2) to compare the adjustment of new available reference equations for the IOS from different countries in a sample of healthy children. Subjects were healthy 4-15-y-old children from the metropolitan area of Mexico City, who performed an IOS test. The functional IOS parameters obtained were compared with the predicted values from 12 reference equations determined in studies of different ethnic groups. The validation methods applied were: analysis of the differences between measured and predicted values for each reference equation; correlation and concordance coefficients; adjustment by Z-score values; percentage of predicted value; and the percentage of patients below the lower limit of normality or above the upper limit of normality. Of the 224 participants, 117 (52.3%) were girls, and the mean age was 8.6 ± 2.3 y. The equations that showed the best adjustment for the different parameters were those from the studies by Nowowiejska et al (2008) and Gochicoa et al (2015). The equations proposed by Frei et al (2005), Hellinckx et al (1998), Kalhoff et al (2011), Klug and Bisgaard (1998), de Assumpção et al (2016), and Dencker et al (2006) overestimated the airway resistance of the children in our sample, whereas the equation of Amra et al (2008) underestimated it. In the analysis of the lower and upper limits of normality, Gochicoa et al equation was the closest, since 5% of subjects were below or above percentiles 5 and 95, respectively. The study found that, in general, all of the equations showed greater error at the extremes of the age distribution. Because of the robust adjustment of the present study reference equations for the IOS, it can be recommended for both

  12. Le Laboratoire de Mécanique Appliquée Raymond Chaléat a 40 ans !

    NASA Astrophysics Data System (ADS)

    Comité D'Organisation Du Colloque Ime 2002, Le

    2002-12-01

    Le LMARC a été créé par Raymond Chaléat dans les locaux de l'École Nationale d'Horlogerie (a présent Lycée Technique Jules Haag).L'équipe de recherche était alors constituée de 2 enseignants-chercheurs (Raymond Chaléat et Gérard Lallement) et d'un technicien (Bernard Prêtre). Les travaux de recherche se situaient naturellement dans le domaine de la chronométrie et en particulier dans la mécanique non linéaire analytique inhérente à la montre en fonctionnement. En effet, Raymond Chaléat fut l'élève, puis le collaborateur du Professeur Jules Haag, mathématicien et mécanicien, lui-même élève de Poincarré.Le LMARC a étendu ses activités avec l'arrivée de Claude Oudet, puis de Claude Oytana à la rhéologie des matériaux solides qui est devenue plus tard l'Équipe Propriétés Mécaniques des Matériaux. En parallèle, G. Lallement a créé une équipe Vibrations devenue à ce jour Dynamique des Structures. À ce jour, le Laboratoire compte plus de 110 personnes dont 40 doctorants.Il a depuis diversifié ses activités avec 3 nouvelles équipes tournées vers la Modélisation et la Mise en Forme des Matériaux, les Micromachines et la Biomécanique et les Mécanismes. Il a su également prendre toute sa place au sein de l'Institut des Microtechniques de Franche-Comté en contribuant à plusieurs thèmes.Notre Laboratoire a été l'un des premiers laboratoires associé au CNRS (4ème) et a toujours été rattaché à l'Université de Franche-Comté (Présidence par C. Oytana de 1996 a 2001) par l'entremise de I'UFR Sciences et Techniques. Il a toujours maintenu des liens forts avec I'ENSMM (École Nationale Supérieure de Mécanique et des Microtechniques) d'une part par ses enseignants-chercheurs et d'autre part deux de ses directeurs, Raymond Chaléat et actuellement Jean-Claude Gelin.En plus de ses relations constantes avec l'industrie régionale, le LMARC a développé des actions contractuelles avec de grands groupes tels que EDF

  13. Web-based Teaching Radio Interferometer for Africa

    NASA Astrophysics Data System (ADS)

    Carignan, Claude

    2015-08-01

    Practical training for the future use of the African VLBI Network (AVN) or any VLBI experiment starts by understanding the basic principles of radio observations and radio interferometry. The aim of this project is to build a basic interferometer that could be used remotely via a web interface from any country on the African continent. This should turn out as a much less expensive and much more efficient way to train AVN researchers from SKA partner countries to the principles of radio astronomy and to interferometric data analysis. The idea is based on the very successful EUHOU (European Hands-On Universe) already very successful in Europe. The former EUHOU manager, Dr Yannick Liebert, arrived for a 3 years postdoc with Prof Claude Carignan at the University of Cape Town to implement the same project on the African continent (AHI: African Hands-on Interferometry). Besides the use of AHI for the AVN researchers, this web-based system could be used be any undergraduate program on radio astronomical techniques across the African continent as the EUHOU is used all across Europe.

  14. The STS-103 crew with loved ones at Pad 39B

    NASA Technical Reports Server (NTRS)

    1999-01-01

    The STS-103 crew pose for photographers with their loved ones at Launch Pad 39B. Space Shuttle Discovery is in the background, next to the Fixed Service Structure lit up like a Christmas tree. Viewed left to right are Mission Specialist Steven L. Smith and his wife, Peggy; Pilot Scott J. Kelly and his wife, Leslie; Commander Curtis L. Brown Jr. and his fiancee, Ann Brickert; Mission Specialist C. Michael Foale; Laurence Clervoy and her husband, Mission Specialist Jean-Frangois Clervoy; Mission Specialist John M. Grunsfeld and his wife, Carol; Mission Specialist Claude Nicollier and his wife, Susana. Nicollier and Clervoy are with the European Space Agency. The mission, to service the Hubble Space Telescope, is scheduled for launch Dec. 17 at 8:47 p.m. EST from Launch Pad 39B. Mission objectives include replacing gyroscopes and an old computer, installing another solid state recorder, and replacing damaged insulation in the telescope. The mission is expected to last about 8 days and 21 hours. Discovery is expected to land at KSC Sunday, Dec. 26, at about 6:25 p.m. EST.

  15. A Genealogy of Animal Diseases and Social Anthropology (1870-2000).

    PubMed

    Keck, Frédéric

    2018-03-23

    Culling, vaccinating, and monitoring animals are the three main techniques used in contemporary veterinary public health to manage animal diseases that can be transmitted to humans. Each technique is underpinned by different ontological understandings of how microbes figure in relations between humans and animals. Therefore, animal diseases are not only a question for an applied anthropology but also involve the theoretical core of the discipline: that is, understanding how social causality emerges out of physical causality. To defend this argument, the article describes what Herbert Spencer wrote about foot-and-mouth disease; what William Robertson Smith thought about sacrifice in the context of bovine tuberculosis; how Emile Durkheim took vaccination for smallpox as a metaphor for the pathologies of the social; and what Claude Lévi-Strauss wrote about mad cow disease. The conceptions of the social in the writing of these four authors are analyzed through their understanding of the risk of transmission of animal diseases to humans, moving from prevention to precaution to preparedness. © 2018 by the American Anthropological Association.

  16. Heat transfer and flow friction correlations for perforated plate matrix heat exchangers

    NASA Astrophysics Data System (ADS)

    Ratna Raju, L.; Kumar, S. Sunil; Chowdhury, K.; Nandi, T. K.

    2017-02-01

    Perforated plate matrix heat exchangers (MHE) are constructed of high conductivity perforated plates stacked alternately with low conductivity spacers. They are being increasingly used in many cryogenic applications including Claude cycle or Reversed Brayton cycle cryo-refrigerators and liquefiers. Design of high NTU (number of (heat) transfer unit) cryogenic MHEs requires accurate heat transfer coefficient and flow friction factor. Thermo-hydraulic behaviour of perforated plates strongly depends on the geometrical parameters. Existing correlations, however, are mostly expressed as functions of Reynolds number only. This causes, for a given configuration, significant variations in coefficients from one correlation to the other. In this paper we present heat transfer and flow friction correlations as functions of all geometrical and other controlling variables. A FluentTM based numerical model has been developed for heat transfer and pressure drop studies over a stack of alternately arranged perforated plates and spacers. The model is validated with the data from literature. Generalized correlations are obtained through regression analysis over a large number of computed data.

  17. STS-75 liftoff - left side close up

    NASA Technical Reports Server (NTRS)

    1996-01-01

    The Space Shuttle Columbia hurtles skyward from Launch Pad 39B. Columbia lifted off right on time at 3:18:00 p.m. EST, Feb. 22, following a smooth countdown. NASA's second Shuttle mission of 1996 and the 75th overall in Shuttle program history will be highlighted by the re-flight of the Tethered Satellite System (TSS-1R) designed to investigate new sources of spacecraft power and ways to study Earth's atmosphere. Mission STS-75 also will see Columbia's seven-person crew work with the U.S. Microgravity Payload (USMP-3), which continues research efforts into development of new materials and processes that could lead to a new generation of computers, electronics and metals. The STS-75 crew includes: Mission Commander Andrew M. Allen; Pilot Scott J. 'Doc' Horowitz; Payload Commander Franklin R. Chang-Diaz; Mission Specialists Jeffrey A. Hoffman, Claude Nicollier and Maurizio Cheli; and Payload Specialist Umberto Guidoni. Nicollier and Cheli represent the European Space Agency (ESA) while Guidoni represents the Italian Space Agency (ASI).

  18. STS-75 liftoff - left side view - closeup

    NASA Technical Reports Server (NTRS)

    1996-01-01

    A smooth countdown culminates in an on-time liftoff as the Space Shuttle Columbia climbs skyward atop a column of flame. The launch from Pad 39B occurred at 3:18:00 P.M. EST, February 22, 1996. Aboard for Mission STS-75 is an international crew headed by Mission Commander Andrew M. Allen; Scott J. 'Doc' Horowitz is pilot; Franklin R. Chang-Diaz is payload commander. Serving as mission specialists are Jeffrey A. Hoffman, Maurizio Cheli and Claude Nicollier. Cheli, from Italy, and Nicollier, from Switzerland, both represent the European Space Agency (ESA). Assigned as payload specialist is Italian Umberto Guidoni, who represents the Italian Space Agency (ASI). During a mission scheduled to last nearly 14 days the flightg crew will be working with two primary parylods: the U.S./Italian Tethered Satellite System (TSS-1R), which is being re-flown, and the U.S. Microgravity Payload (USMP-3), making its third spaceflight. Mission STS-75 marks the second Shuttle flight of 1996 and the 75th Shuttle launch overall.

  19. STS-75 liftoff - left side view from across marsh

    NASA Technical Reports Server (NTRS)

    1996-01-01

    A smooth countdown culminates in an on-time liftoff as the Space Shuttle Columbia climbs skyward atop a column of flame. The launch from Pad 39B occurred at 3:18:00 P.M. EST, February 22, 1996. Aboard for Mission STS-75 is an international crew headed by Mission Commander Andrew M. Allen; Scott J. 'Doc' Horowitz is pilot; Franklin R. Chang-Diaz is payload commander. Serving as mission specialists are Jeffrey A. Hoffman, Maurizio Cheli and Claude Nicollier. Cheli, from Italy, and Nicollier, from Switzerland, both represent the European Space Agency (ESA). Assigned as payload specialist is Italian Umberto Guidoni, who represents the Italian Space Agency (ASI). During a mission scheduled to last nearly 14 days the flightg crew will be working with two primary parylods: the U.S./Italian Tethered Satellite System (TSS-1R), which is being re-flown, and the U.S. Microgravity Payload (USMP-3), making its third spaceflight. Mission STS-75 marks the second Shuttle flight of 1996 and the 75th Shuttle launch overall.

  20. Living Together Apart in France and the United States

    PubMed Central

    Martin, Claude; Cherlin, Andrew; Cross-Barnet, Caitlin

    2014-01-01

    Union formation involves a number of stages, as does union dissolution, and new couples often spend an initial period in a non-cohabiting intimate relationship. Yet while certain couples never share the same dwelling, “living apart together”1 has not developed widely as a long-term lifestyle option. Claude Martin in France, and Andrew Cherlin and Caitlin Cross-Barnet in the United States have studied a symmetrical phenomenon, that of couples who continue to live together while considering themselves to be separated. In this article, they draw together their analyses to describe an arrangement which, while marginal, reveals situations where residential separation is not possible, either because of the need to keep up appearances, often for the children’s sake, or because total separation is too frightening or living in separate homes is unaffordable. Beyond the differences between the two countries and the two survey fields, the authors analyse the ways in which persons who “live together apart” describe their loveless relationship that has led to explicit conjugal separation within a shared home. PMID:25170338

  1. Clinical and surgical anatomy of the liver: a review for clinicians.

    PubMed

    Juza, Ryan M; Pauli, Eric M

    2014-07-01

    The liver is the largest gland in the body occupying 2.5% of total body weight and providing a host of functions necessary for maintaining normal physiological homeostasis. Despite the complexity of its functions, the liver has a homogenous appearance, making hepatic anatomy a challenging topic of discussion. To address this issue, scholars have devoted time to establishing a framework for describing hepatic anatomy to aid clinicians. Work by the anatomist Sir James Cantlie provided the first accurate division between the right and left liver in 1897. The French surgeon and anatomist Claude Couinaud provided additional insight by introducing the Couinaud segments on the basis of hepatic vasculature. These fundamental studies provided a framework for medical and surgical discussions of hepatic anatomy and were essential for the advancement of modern medicine. In this article, the authors review the normal anatomy and physiology of the liver with a view to enhancing the clinician's knowledge base. They also provide a convenient model to assist with understanding and discussion of liver anatomy. Copyright © 2014 Wiley Periodicals, Inc.

  2. Epidemiology: second-rate science?

    PubMed

    Parascandola, M

    1998-01-01

    In recent years epidemiology has come under increasing criticism in regulatory and public arenas for being "unscientific." The tobacco industry has taken advantage of this, insisting for decades that evidence linking cigarettes and lung cancer falls short of proof. Moreover, many epidemiologists remain unduly skeptical and self-conscious about the status of their own causal claims. This situation persists in part because of a widespread belief that only the laboratory can provide evidence sufficient for scientific proof. Adherents of this view erroneously believe that there is no element of uncertainty or inductive inference in the "direct observation" of the laboratory researcher and that epidemiology provides mere "circumstantial" evidence. The historical roots of this attitude can be traced to philosopher John Stuart Mill and physiologist Claude Bernard and their influence on modern experimental thinking. The author uses the debate over cigarettes and lung cancer to examine ideas of proof in medical science and public health, concluding that inductive inference from a limited sample to a larger population is an element in all empirical science.

  3. [Osteosynthesis of distal radius fractures by by flexible intramedullary nailing (Geneva experience)].

    PubMed

    Flisch, C W; Della Santa, D R

    1998-01-01

    In 1949 Leslie Rush described a new method of management of Colles' fractures by means of a rigid medullary nail. Claude Py in 1969 followed this concept but used two flexible intramedullary pins. After briefly recalling the biomechanical principle and operating technique, the authors outline their series of 39 extra- and intra-articular fractures (10 males and 29 females) operated between March 1995 and April 1996 with an average follow-up of 6.5 months (1.5-14.5 months). The radiological and functional results are discussed: 55% of the cases showed good anatomical reduction whereas 59% achieved a satisfactory functional result. The advantage of this operating technique lies in its simplicity. Nevertheless, considerable experience is necessary owing to the relatively high complication rate (secondary displacement, tendon or nerve lesions, reflex sympathetic dystrophy). However, this method requires only a limited amount of time and remains a good indication for extra-articular and simple articular fractures. In the case of severe posterior comminution, the use of cancellous bone graft can help to prevent secondary dorsal impaction and its repercussion on distal radio-ulnar function.

  4. Anatomic variants in Dandy-Walker complex.

    PubMed

    Jurcă, Maria Claudia; Kozma, Kinga; Petcheşi, CodruŢa Diana; Bembea, Marius; Pop, Ovidiu Laurean; MuŢiu, Gabriela; Coroi, Mihaela Cristiana; Jurcă, Alexandru Daniel; Dobjanschi, Luciana

    2017-01-01

    Dandy-Walker complex (DWC) is a malformative association of the central nervous system. DWC includes four different types: Dandy-Walker malformation (vermis agenesis or hypoplasia, cystic dilatation of the fourth ventricle and a large posterior fossa); Dandy-Walker variant (vermis hypoplasia, cystic dilatation of the fourth ventricle, normal posterior fossa); mega cysterna magna (large posterior fossa, normal vermis and fourth ventricle) and posterior fossa arachnoid cyst. We present and discuss four cases with different morphological and clinical forms of the Dandy-Walker complex. In all four cases, diagnosis was reached by incorporation of clinical (macrocephaly, seizures) and imaging [X-ray, computed tomography (CT), magnetic resonance imaging (MRI)] data. Two patients were diagnosed with Dandy-Walker complex, one patient was diagnosed with Dandy-Walker variant in a rare association with neurofibromatosis and one patient was diagnosed with a posterior fossa arachnoid cyst associated with left-sided Claude Bernard-Horner syndrome, congenital heart disease (coarctation of the aorta, mitral stenosis) and gastroesophageal reflux. In all forms of DWC, the clinical, radiological and functional manifestations are variable and require adequate diagnostic and therapeutic measures.

  5. Developing a quality assurance program for online services.

    PubMed Central

    Humphries, A W; Naisawald, G V

    1991-01-01

    A quality assurance (QA) program provides not only a mechanism for establishing training and competency standards, but also a method for continuously monitoring current service practices to correct shortcomings. The typical QA cycle includes these basic steps: select subject for review, establish measurable standards, evaluate existing services using the standards, identify problems, implement solutions, and reevaluate services. The Claude Moore Health Sciences Library (CMHSL) developed a quality assurance program for online services designed to evaluate services against specific criteria identified by research studies as being important to customer satisfaction. These criteria include reliability, responsiveness, approachability, communication, and physical factors. The application of these criteria to the library's existing online services in the quality review process is discussed with specific examples of the problems identified in each service area, as well as the solutions implemented to correct deficiencies. The application of the QA cycle to an online services program serves as a model of possible interventions. The use of QA principles to enhance online service quality can be extended to other library service areas. PMID:1909197

  6. Developing a quality assurance program for online services.

    PubMed

    Humphries, A W; Naisawald, G V

    1991-07-01

    A quality assurance (QA) program provides not only a mechanism for establishing training and competency standards, but also a method for continuously monitoring current service practices to correct shortcomings. The typical QA cycle includes these basic steps: select subject for review, establish measurable standards, evaluate existing services using the standards, identify problems, implement solutions, and reevaluate services. The Claude Moore Health Sciences Library (CMHSL) developed a quality assurance program for online services designed to evaluate services against specific criteria identified by research studies as being important to customer satisfaction. These criteria include reliability, responsiveness, approachability, communication, and physical factors. The application of these criteria to the library's existing online services in the quality review process is discussed with specific examples of the problems identified in each service area, as well as the solutions implemented to correct deficiencies. The application of the QA cycle to an online services program serves as a model of possible interventions. The use of QA principles to enhance online service quality can be extended to other library service areas.

  7. Interactions of Pannexin1 channels with purinergic and NMDA receptor channels.

    PubMed

    Li, Shuo; Bjelobaba, Ivana; Stojilkovic, Stanko S

    2018-01-01

    Pannexins are a three-member family of vertebrate plasma membrane spanning molecules that have homology to the invertebrate gap junction forming proteins, the innexins. However, pannexins do not form gap junctions but operate as plasma membrane channels. The best-characterized member of these proteins, Pannexin1 (Panx1) was suggested to be functionally associated with purinergic P2X and N-methyl-D-aspartate (NMDA) receptor channels. Activation of these receptor channels by their endogenous ligands leads to cross-activation of Panx1 channels. This in turn potentiates P2X and NMDA receptor channel signaling. Two potentiation concepts have been suggested: enhancement of the current responses and/or sustained receptor channel activation by ATP released through Panx1 pore and adenosine generated by ectonucleotidase-dependent dephosphorylation of ATP. Here we summarize the current knowledge and hypotheses about interactions of Panx1 channels with P2X and NMDA receptor channels. This article is part of a Special Issue entitled: Gap Junction Proteins edited by Jean Claude Herve. Published by Elsevier B.V.

  8. Operational experience of the OC-OTEC experiments at NELH

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Link, H

    1989-02-01

    The Solar Energy Research Institute, under funding and program direction from the US Department of Energy, has been operating a small-scale test apparatus to investigate key components of open- cycle ocean thermal energy conversion (OC-OTEC). The apparatus started operations in October 1987 and continues to provide valuable information on heat-and mass-transfer processes in evaporators and condensers, gas sorption processes as seawater is depressurized and repressurized, and control and instrumentation characteristics of open-cycle systems. Although other test facilities have been used to study some of these interactions, this is the largest apparatus of its kind to use seawater since Georges Claude`smore » efforts in 1926. The information obtained from experiments conducted in this apparatus is being used to design a larger scale experiment in which a positive net power production is expected to be demonstrated for the first time with OC-OTEC. This paper describes the apparatus, the major tests conducted during its first 18 months of operation, and the experience gained in OC-OTEC system operation. 13 refs., 8 figs.« less

  9. [A brief history of the anatomy and physiology of a mysterious and hidden gland called the pancreas].

    PubMed

    Navarro, Salvador

    2014-11-01

    Because of its retrogastric location and appearance, which is similar to mesenteric fat, for centuries the pancreas has been a mysterious, hidden organ that has received little attention. However, its importance was intuited and described by Herophilus, Ruphos of Ephesus and Galen. This gland began to appearin distinct medical treatises from the 16th century. There are two important scientists in the history of the pancreas. The fist, Johann Georg Wirsung, described the main pancreatic duct in 1642, a date considered by many to be the start of Pancreatology. The second, Claude Bernard, described pancreatic exocrine function between 1849 and 1856 and is considered the father of pancreatic physiology. Besides these two outstanding figures, there is a constellation of personalities who contributed to improving knowledge of this enigmatic gland with the results of their studies. The aim of this article is to call attention to some of the most notable findings that have enhanced knowledge of this gland over the years. Copyright © 2014 Elsevier España, S.L.U. and AEEH y AEG. All rights reserved.

  10. STS-46 post flight press conference

    NASA Astrophysics Data System (ADS)

    1992-08-01

    At a post flight press conference, the flight crew of the STS-46 mission (Cmdr. Loren Shriver, Pilot Andrew Allen, Mission Specialists Claude Nicollier (European Space Agency (ESA)), Marsha Ivins (Flight Engineer), Jeff Hoffman (Payload Commander), Franklin Chang-Dias, and Payload Specialist Franco Malerba (Italian Space Agency (ISA))) discussed their roles in and presented video footage, slides and still photographs of the different aspects of their mission. The primary objectives of the mission were the deployment of ESA's European Retrievable Carrier (EURECA) satellite and the joint NASA/ISA deployment and testing of the Tethered Satellite System (TSS). Secondary objectives included the IMAX Camera, the Limited Duration Space Environment Candidate Materials Exposure (LDVE), and the Pituitary Growth Hormone Cell Function (PHCF) experiments. Video footage of the EURECA and TSS deployment procedures are shown. Earth views were extensive and included Javanese volcanoes, Amazon basin forest ground fires, southern Mexico, southern Bolivian volcanoes, south-west Sudan and the Sahara Desert, and Melville Island, Australia. Questions from reporters and journalists from Johnson Space Center and Kennedy Space Center were discussed.

  11. STS-46 Post Flight Press Conference

    NASA Technical Reports Server (NTRS)

    1992-01-01

    At a post flight press conference, the flight crew of the STS-46 mission (Cmdr. Loren Shriver, Pilot Andrew Allen, Mission Specialists Claude Nicollier (European Space Agency (ESA)), Marsha Ivins (Flight Engineer), Jeff Hoffman (Payload Commander), Franklin Chang-Dias, and Payload Specialist Franco Malerba (Italian Space Agency (ISA))) discussed their roles in and presented video footage, slides and still photographs of the different aspects of their mission. The primary objectives of the mission were the deployment of ESA's European Retrievable Carrier (EURECA) satellite and the joint NASA/ISA deployment and testing of the Tethered Satellite System (TSS). Secondary objectives included the IMAX Camera, the Limited Duration Space Environment Candidate Materials Exposure (LDVE), and the Pituitary Growth Hormone Cell Function (PHCF) experiments. Video footage of the EURECA and TSS deployment procedures are shown. Earth views were extensive and included Javanese volcanoes, Amazon basin forest ground fires, southern Mexico, southern Bolivian volcanoes, south-west Sudan and the Sahara Desert, and Melville Island, Australia. Questions from reporters and journalists from Johnson Space Center and Kennedy Space Center were discussed.

  12. INVITED SPEAKERS Invited Speakers

    NASA Astrophysics Data System (ADS)

    2011-01-01

    Alain AspectPalaiseau Markus AspelmeyerVienna Vanderlei BagnatoSão Paulo Victor BalykinMoscow Kristian BaumannZürich Jim BergquistNIST, Boulder Frédéric ChevyENS, Paris John CloseCanberra Claude Cohen-TannoudjiENS, Paris Jean DalibardENS, Paris Eugene DemlerHarvard Michael DoserCERN Markus DrescherHamburg Francesca FerlainoInnsbruck Victor FlambaumSydney Chiara FortFlorence Elisabeth GiacobinoENS, Paris Philippe GrangierPalaiseau Chris GreeneJILA, Boulder Markus GreinerHarvard Eric HesselsToronto Hidetoshi KatoriTokyo Wolfgang KetterleMIT Michael KohlCambridge Wu-Ming LiuBeijing Francesco MinardiFlorence Holger MüllerBerkeley Karim MurrGarching Hanns-Christoph NägerlInnsbruck Jeremy O'BrienBristol Silke OspelkausJILA, Boulder Krzysztof PachuckiWarsaw Bill PhillipsGaithersburg Randolf PohlGarching Eugene PolzikCopenhagen Cindy RegalJILA, Boulder Jakob ReichelENS, Paris Helmut RitschInnsbruck Christian RoosInnsbruck Mark SaffmanWisconsin Christophe SalomonENS, Paris Gora ShlyapnikovOrsay Richard TaiebParis Masahito UedaTokyo Chris ValeMelbourne Andreas WallraffZürich Matthias WeidemüllerHeidelberg Martin WeitzBonn Artur WideraBonn David WinelandNIST, Boulder

  13. Thermodynamic Analysis on of Skid-Mounted Coal-bed Methane Liquefaction Device using Cryogenic Turbo-Expander

    NASA Astrophysics Data System (ADS)

    Chen, Shuangtao; Niu, Lu; Zeng, Qiang; Li, Xiaojiang; Lou, Fang; Chen, Liang; Hou, Yu

    2017-12-01

    Coal-bed methane (CBM) reserves are rich in Sinkiang of China, and liquefaction is a critical step for the CBM exploration and utilization. Different from other CBM gas fields in China, CBM distribution in Sinkiang is widespread but scattered, and the pressure, flow-rate and nitrogen content of CBM feed vary significantly. The skid-mounted liquefaction device is suggested as an efficient and economical way to recover methane. Turbo-expander is one of the most important parts which generates the cooling capacity for the cryogenic liquefaction system. Using turbo-expander, more cooling capacity and higher liquefied fraction can be achieved. In this study, skid-mounted CBM liquefaction processes based on Claude cycle are established. Cryogenic turbo-expander with high expansion ratio is employed to improve the efficiency of CBM liquefaction process. The unit power consumption per liquefaction mole flow-rate for CBM feed gas is used as the object function for process optimization, compressor discharge pressure, flow ratio of feed gas to turbo-expander and nitrogen friction are analyzed, and optimum operation range of the liquefaction processes are obtained.

  14. The birth of the most important 18th century dental text: Pierre Fauchard's Le Chirurgien Dentiste.

    PubMed

    Spielman, Andrew I

    2007-10-01

    Pierre Fauchard (1678-1761) is considered the father of modern dentistry. His seminal book, Le Chirurgien Dentiste, ou Traité des Dents (1728), is the discipline's first complete work. During the five years preceding its publication (1723-1728), Pierre Fauchard sought the opinions, contributions, and "approbation" (approval) of 19 of his colleagues: six physicians, 12 surgeons, and one dentist. The first and most important contributor to the manuscript was Jean Devaux, surgeon and mentor to Fauchard. The next six reviewers were illustrious physicians and scientists of the time: Philippe Hecquet, Jean-Claude Adrien Helvetius, Jean Baptiste Silva, Antoine DeJussieu, Raymond Jacob Finot, and Antoine Benignus Winslow. The subsequent 12 reviewers were all sworn-surgeons (certified by St. Côme), including a lone dentist, Laudumiey, surgeon-dentist to His Majesty, Philip V, King of Spain. Fauchard knew that for dentistry to be regarded as a learned profession, and perhaps for Fauchard to be recognized as its leader, he needed the support and approval of the establishment before publishing his book. This is an account of how he attained this endorsement.

  15. Dynamical systems theory and applications

    NASA Astrophysics Data System (ADS)

    Awrejcewicz, Jan

    2006-08-01

    The 7th International Conference devoted to "Dynamical Systems-Theory and Applications" hold in 8-11 December, 2003 in Łódź, Poland, and it was organized by the staff of Department of Automatics and Biomechanics of the Technical University of Łódź. It was financially supported by the Rector of the Technical University of Łódź and the Department of Education and Physical Culture of the Łódź City Hall. The members of the International Scientific Committee included: Igor V. Andrianov (Dniepropetrovsk), Jan Awrejcewicz (Łódź), Iliya Blekhman (Sankt Petersburg), Roman Bogacz (Warszawa), Dick van Campen (Eindhoven), Zbigniew Engel (Kraków), Lothar Gaul (Stuttgart), Józef Giergiel (Kraków), Michał Kleiber (Warszawa), Vadim A. Krysko (Saratov), Włodzimierz Kurnik (Warszawa), Claude-Henri Lamarque (Lyon), Leonid I. Manevitch (Moscow), Jan Osiecki (Warszawa), Wiesaw Ostachowicz (Gdańsk), Ladislav Pust (Prague), Giuseppe Rega (Rome), Tsuneo Someya (Tokyo), Zbigniew Starczewski (Warszawa), Eugeniusz Świtoński (Gliwice), Andrzej Tylikowski (Warszawa), Tadeusz Uhl (Kraków), Aleksander F. Vakakis (Illinois), Józef Wojnarowski (Gliwice).

  16. STS-103 Discovery crawls to Launch Pad 39B

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Space Shuttle Discovery, atop the mobile launcher platform and crawler transporter, nears the top of Launch Pad 39B after a 4.2-mile crawl from the Vehicle Assembly Building. At left are the Rotating Service Structure and the Fixed Service Structure, which will enable final preparations of the orbiter, external tank and solid rocket boosters for the STS-103 launch targeted for Dec. 6, 1999, at 2:37 a.m. EST. The mission is a 'call-up' due to the need to replace and repair portions of the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The STS-103 crew members are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), and Claude Nicollier of Switzerland and Jean-Frangois Clervoy of France, both with the European Space Agency.

  17. STS-103 Discovery crawls to Launch Pad 39B

    NASA Technical Reports Server (NTRS)

    1999-01-01

    With the American flag flapping in the morning breeze, Space Shuttle Discovery across the turn basin makes its 4.2-mile (6.8 kilometer) crawl to Launch Pad 39B (background, left) atop the mobile launcher platform and crawler transporter. Once at the pad, the orbiter, external tank and solid rocket boosters will undergo final preparations for the STS-103 launch targeted for Dec. 6, 1999, at 2:37 a.m. EST. The mission is a 'call-up' due to the need to replace and repair portions of the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The STS-103 crew members are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), and Claude Nicollier of Switzerland and Jean-Frangois Clervoy of France, both with the European Space Agency.

  18. European Glaucoma Society Terminology and Guidelines for Glaucoma, 4th Edition - Part 1Supported by the EGS Foundation

    PubMed Central

    2017-01-01

    Nordmann Norbert Pfeiffer Luis Abegao Pinto Luca Rossetti John Salmon Leo Schmetterer Riccardo Scotto Tarek Shaarawy Ingeborg Stalmans Gordana Sunaric Megevand Ernst Tamm John Thygesen Fotis Topouzis Carlo Enrico Traverso Anja Tuulonen Ananth Viswanathan Thierry Zeyen The Guidelines Task Force  Luca Bagnasco Anders Heijl Carlo Enrico Traverso Augusto Azuara Blanco Alessandro Bagnis David Garway Heath Michele Iester Yves Lachkar Ingeborg Stalmans Gordana Sunaric Mégevand Fotis Topouzis Anja Tuulonen Ananth Viswanathan The EGS Executive Committee  Carlo Enrico Traverso (President) Anja Tuulonen (Vice President) Roger Hitchings (Past President) Anton Hommer (Treasurer) Barbara Cvenkel Julian Garcia Feijoo David Garway Heath Norbert Pfeiffer Ingeborg Stalmans The Board of the European Glaucoma Society Foundation  Roger Hitchings (Chair) Carlo E. Traverso (Vice Chair) Franz Grehn Anders Heijl John Thygesen Fotis Topouzis Thierry Zeyen The EGS Committees  CME and Certification  Gordana Sunaric Mégevand (Chair) Carlo Enrico Traverso (Co-chair) Delivery of Care  Anton Hommer (Chair) EU Action  Thierry Zeyen (Chair) Carlo E. Traverso (Co-chair) Education  John Thygesen (Chair) Fotis Topouzis (Co-chair) Glaucogene  Ananth Viswanathan (Chair) Fotis Topouzis (Co-chair) Industry Liaison  Roger Hitchings (Chair) Information Technology  Ingeborg Stalmans (Chair) Carlo E. Traverso (Co-chair) National Society Liaison  Anders Heijl (Chair) Program Planning  Fotis Topouzis (Chair) Ingeborg Stalmans (Co-chair) Quality and Outcomes  Anja Tuulonen (Chair) Augusto Azuara Blanco (Co-chair) Scientific  Franz Grehn (Chair) David Garway Heath (Co-chair) PMID:27378485

  19. Magmatic processes evidenced by borehole dilatometer data at Campi Flegrei, Italy.

    NASA Astrophysics Data System (ADS)

    Di Lieto, Bellina; Romano, Pierdomenico; Scarpa, Roberto; Orazi, Massimo

    2017-04-01

    Since spring 2004 a joint research project (AMRA, UniSa, INGV) has been developed in Italy to install borehole strainmeters aimed at enhanced INGV monitoring systems. Six Sacks-Evertson dilatometers were installed around Campi Flegrei and Vesuvius during 2004-2005, and in 2008 these were supplemented by two arrays of long-baseline underground water tube tiltmeters. Renewed activity started since 2004-2005, characterized by a low rate of vertical displacement, amounting initially to a few cm/year. Recent deformation in the Campi Flegrei caldera is dominated by aseismic inflation, interrupted by minor transient aseismic reversals in rate. These are typically below the noise level or are poorly sampled by the low sampling frequency of most geodetic techniques, but can be quantified relatively easily using high sensitivity strainmeters and tiltmeters. These instruments provide coherent views of deformation at several different time scales capturing reversals in rate with periods from minutes to months. Monotonic uplift episodes have been recorded with durations of several weeks to a few years. During the summer of 2006 a long term strain episode related to an increase of CO2 emission, evidenced by borehole tiltmeters and continuous GPS sensors, has been observed by the borehole dilatometers array. This strain episode preceded caldera microseismic activity by few months, as was also observed during the 1982 period of unrest. Other aseismic slip episodes were recorded in October 2006 and in March 2010, several minutes before the most significant seismic swarms (VT and/or LP events) occurred after the 1982-1984 uplift. The time scale of these transient strain events lasted less than one hour, putting further constraints on the origin of ground uplifts at Campi Flegrei. Their locations are compatible with the source inferred from long term deformation signals, at about 4 km depth beneath Pozzuoli. The current array provides us with a glimpse of the potential utility of a

  20. Radio Telescopes Reveal Youngest Stellar Corpse

    NASA Astrophysics Data System (ADS)

    2004-06-01

    Astronomers using a global combination of radio telescopes to study a stellar explosion some 30 million light-years from Earth have likely discovered either the youngest black hole or the youngest neutron star known in the Universe. Their discovery also marks the first time that a black hole or neutron star has been found associated with a supernova that has been seen to explode since the invention of the telescope nearly 400 years ago. M51 An artist's impression of Supernova 1986J. The newly discovered nebula around the black hole or neutron star in the center is shown in blue, and is in the center of the expanding, fragmented shell of material thrown off in the supernova explosion, which is shown in red. CREDIT: Norbert Bartel and Michael F. Bietenholz, York University; Artist: G. Arguner (Click on image for larger version) Image Files Artist's Conception (above image, 836K) Galaxy and Supernova (47K) A VLA image (left) of the galaxy NGC 891, showing the bright supernova explosion below the galaxy's center. At right, a closer view of the supernova, made with a global array of radio telescopes. CREDIT: Miguel A. Perez-Torres, Antxon Alberdi and Lucas Lara, Instituto de Astrofisica de Andalucia - CSIC, Spain, Jon Marcaide and Jose C. Guirado, Universidad de Valencia, Spain Franco Mantovani, IRA-CNR, Italy, Eduardo Ros, MPIfR, Germany, and Kurt W. Weiler, Naval Research Laboratory, USA Multi-Frequency Closeup View (201K) Blue and white area shows the nebula surrounding the black hole or neutron star lurking in the center of the supernova. This nebula is apparent at a higher radio frequency (15 GHz). The red and also the contours show the distorted, expanding shell of material thrown off in the supernova explosion. This shell is seen at a lower radio frequency (5 GHz). CREDIT: Michael F. Bietenholz and Norbert Bartel, York University, Michael Rupen, NRAO, NRAO/AUI/NSF A supernova is the explosion of a massive star after it exhausts its supply of nuclear fuel and

  1. Laws, leaders, and legends of the modern National Library of Medicine

    PubMed Central

    Smith, Kent A.

    2008-01-01

    Purpose: The paper is an expanded version of the 2007 Joseph Leiter National Library of Medicine (NLM)/Medical Library Association Lecture presented at MLA ‘07, the Medical Library Association annual meeting in Philadelphia in May 2007. It presents an historical accounting of four major pieces of legislation, beginning with the NLM Act of 1956 up through the creation of the National Center for Biotechnology Information. Brief Description: The transition from the United States Armed Forces Medical Library to the United States National Library of Medicine in 1956 was a major turning point in NLM's history, scope, and direction. The succeeding landmark legislative achievements—namely, the 1965 Medical Library Assistance Act, the 1968 Joint Resolution forming the Lister Hill National Center for Biomedical Communications, and the 1988 authorization for the National Center for Biotechnology Information— transformed the library into a major biomedical communications institution and a leader and supporter of an effective national network of libraries of medicine. The leaders of the library and its major advocates—including Dr. Michael DeBakey, Senator Lister Hill, and Senator Claude Pepper—together contributed to the creation of the modern NLM. PMID:18379667

  2. Providing consumer health information through institutional collaboration.

    PubMed Central

    Humphries, A W; Kochi, J K

    1994-01-01

    In the past several years, The Claude Moore Health Sciences Library of the University of Virginia Health Sciences Center (HSC) has noted a growing demand for consumer health information. However, because the primary role of the library is to provide information services to health professionals at the HSC, questions have been raised as to the amount of time, energy, and money that should be expended to provide health care information to consumers. The library staff, because it can provide special expertise regarding the availability and utilization of consumer health materials, has felt the responsibility to participate in HSC initiatives that reach a broad audience. Library efforts in that regard include assisting with inventory and management of patient education materials, participating in a community health promotion task force, collaborating with hospital departments in planning a consumer health information center, establishing a consumer health information reference section in the library, and obtaining a grant to offer a networked health information system to local public and community college libraries. Consumers of health information benefit from the enhanced services that result from combining the expertise of health professionals and patient educators with the information management skills of library staff. PMID:8136761

  3. Active space debris removal by using laser propulsion

    NASA Astrophysics Data System (ADS)

    Rezunkov, Yu. A.

    2013-03-01

    At present, a few projects on the space debris removal by using highpower lasers are developed. One of the established projects is the ORION proposed by Claude Phipps from Photonics Associates Company and supported by NASA (USA) [1]. But the technical feasibility of the concept is limited by sizes of the debris objects (from 1 to 10 cm) because of a small thrust impulse generated at the laser ablation of the debris materials. At the same time, the removal of rocket upper stages and satellites, which have reached the end of their lives, has been carried out only in a very small number of cases and most of them remain on the Low Earth Orbits (LEO). To reduce the amount of these large-size objects, designing of space systems allowing deorbiting upper rocket stages and removing large-size satellite remnants from economically and scientifically useful orbits to disposal ones is considered. The suggested system is based on high-power laser propulsion. Laser-Orbital Transfer Vehicle (LOTV) with the developed aerospace laser propulsion engine is considered as applied to the problem of mitigation of man-made large-size space debris in LEO.

  4. STS-103 M.S. Steven Smith during TCDT activities

    NASA Technical Reports Server (NTRS)

    1999-01-01

    STS-103 Mission Specialist Steven L. Smith gets ready to practice driving a small armored personnel carrier that is part of emergency egress training during Terminal Countdown Demonstration Test (TCDT) activities. The tracked vehicle could be used by the crew in the event of an emergency at the pad during which the crew must make a quick exit from the area. The TCDT also provides simulated countdown exercises and opportunities to inspect the mission payloads in the orbiter's payload bay. STS-103 is a 'call-up' mission due to the need to replace and repair portions of the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The other STS-103 crew members are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, and Mission Specialists John M. Grunsfeld (Ph.D.), C. Michael Foale (Ph.D.), (Ph.D.), and Claude Nicollier of Switzerland and Jean-Frangois Clervoy of France, who are with the European Space Agency. The mission is targeted for launch Dec. 6 at 2:37 a.m. EST.

  5. STS-103: Flight Day 6 Highlights and Crew Activities Report

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Discovery's astronauts (Mission Commander, Curtis L. Brown; Pilot, Scott J. Kelly; Mission Specialists, Steven L. Smith, C. Michael Foale, and John M. Grunsfeld; and (ESA) Mission Specialists, Claude Nicollier and Jean-Francois Clervoy) deliver a Christmas present to the world, putting the Hubble Space Telescope back into service after 24 hours and 33 minutes of repairs and upgrades that make the orbital observatory more capable than ever. European Space Agency Astronaut Jean-Francois Clervoy uses the shuttle's robot arm to release the telescope at 5:03 p.m. CST, then places the arm into an upright salute as Commander Curt Brown fires Discovery's steering jets to begin separating from the telescope. The telescope's re-deployment takes place at an altitude of 370 statute miles as the two spacecraft fly over the South Pacific's coral sea northeast of Australia. At 5:39 CST, Brown executes a second steering jet burn, lowering Discovery's orbit slightly, so that it will begin orbiting faster than the telescope and move away at just under 6 statute miles per orbit. Afterward, each of the seven astronauts on board calls down holiday wishes from space in several languages.

  6. Epidemiology: second-rate science?

    PubMed Central

    Parascandola, M

    1998-01-01

    In recent years epidemiology has come under increasing criticism in regulatory and public arenas for being "unscientific." The tobacco industry has taken advantage of this, insisting for decades that evidence linking cigarettes and lung cancer falls short of proof. Moreover, many epidemiologists remain unduly skeptical and self-conscious about the status of their own causal claims. This situation persists in part because of a widespread belief that only the laboratory can provide evidence sufficient for scientific proof. Adherents of this view erroneously believe that there is no element of uncertainty or inductive inference in the "direct observation" of the laboratory researcher and that epidemiology provides mere "circumstantial" evidence. The historical roots of this attitude can be traced to philosopher John Stuart Mill and physiologist Claude Bernard and their influence on modern experimental thinking. The author uses the debate over cigarettes and lung cancer to examine ideas of proof in medical science and public health, concluding that inductive inference from a limited sample to a larger population is an element in all empirical science. Images p313-a p317-a p318-a PMID:9672568

  7. The mitochondrial pyruvate carrier in health and disease: To carry or not to carry?

    PubMed

    Bender, Tom; Martinou, Jean-Claude

    2016-10-01

    Mitochondria play a key role in energy metabolism, hosting the machinery for oxidative phosphorylation, the most efficient cellular pathway for generating ATP. A major checkpoint in this process is the transport of pyruvate produced by cytosolic glycolysis into the mitochondrial matrix, which is accomplished by the recently identified mitochondrial pyruvate carrier (MPC). As the gatekeeper for pyruvate entry into mitochondria, the MPC is thought to be of fundamental importance in establishing the metabolic programming of a cell. This is especially relevant in the context of the aerobic glycolysis, also known as the Warburg effect, which is a hallmark in many types of cancer, and MPC loss of function promotes cancer growth. Moreover, mitochondrial pyruvate uptake is needed for efficient hepatic gluconeogenesis and the regulation of blood glucose levels. In this review we discuss recent advances in our knowledge of the MPC, and we argue that it may offer a promising target in diseases like cancer and type 2 diabetes. This article is part of a Special Issue entitled: Mitochondrial Channels edited by Pierre Sonveaux, Pierre Maechler and Jean-Claude Martinou. Copyright © 2016 Elsevier B.V. All rights reserved.

  8. A retrospective study of daptomycin use in a Paris teaching-hospital.

    PubMed

    Marc, F; Esquirol, C; Papy, E; Longuet, P; Armand-Lefevre, L; Rioux, C; Diamantis, S; Dumortier, C; Bourgeois-Nicolaos, N; Lucet, J-C; Wolff, M; Arnaud, P

    2014-01-01

    We retrospectively studied daptomycin use during 2010 at the Bichat-Claude-Bernard teaching-hospital (Paris) to observe the evolution of daptomycin prescriptions. Twenty-one patients were included and several parameters were documented: site of infection, bacterial species involved, reason for daptomycin use, dose and clinical outcome. Ninety-five percent of daptomycin prescritions were off-label and most did not comply with local guidelines. Fifteen of the 21 patients were cured (71%), including 9 patients of the 12 with off-label and off-local recommendation prescriptions (75%). Osteitis and Enterococcus spp endocarditis were the new indications. Daptomycin was increasingly used at higher doses: 52% of our patients were given doses above 6mg/kg. Staphylococcus spp. was the most frequent pathogen responsible for infection is our patients, followed by Enterococcus spp. Daptomycin use is likely to evolve because of its effectiveness in the treatment of osteitis, left-sided and Enterococcus spp. infective endocarditis. It is generally used at higher doses, which are well tolerated. However, therapeutic monitoring needs to be developed. The antibiotic commission of our hospital gave new recommendations for daptomycin use in 2011. Copyright © 2013 Elsevier Masson SAS. All rights reserved.

  9. A History of Chemistry (by Bernadette Bensaude-Vincent and Isabelle Stengers)

    NASA Astrophysics Data System (ADS)

    Kauffman, George B.

    1998-06-01

    translated by Deborah van Dam. Harvard University Press: Cambridge, MA and London, 1997. 305 pp. Illustrations. 16.3 x 24.0 cm. ISBN 0-674-39659-6. $35.00, £23.50. Another history of chemistry? When I studied the subject in 1950 in the late Claude K. Deischer's class at the University of Pennsylvania, our text was Frank J. Moore's A History of Chemistry (1918; 3rd ed., 1939), one of the few books, all written by practicing chemists, then available in English. Now, paradoxically, at a time when such classes are no longer a standard part of the usual undergraduate curriculum, we are treated to a plethora of histories, most written by professional historians of science. In two recent years alone four histories have appeared: David M. Knight's Ideas in Chemistry: A History of the Science (Rutgers University Press, 1992), William H. Brock's The History of Chemistry (Chapman & Hall, 1992), William H. Brock's The Norton History of Chemistry (Norton, 1993), and Bernadette Bensaude-Vincent and Isabelle Stengers's Histoire de la Chimie (Editions de la Decuoverte, 1993). The book under review here is a felicitous English translation of the last-named volume.

  10. Conditioning from an information processing perspective.

    PubMed

    Gallistel, C R.

    2003-04-28

    The framework provided by Claude Shannon's [Bell Syst. Technol. J. 27 (1948) 623] theory of information leads to a quantitatively oriented reconceptualization of the processes that mediate conditioning. The focus shifts from processes set in motion by individual events to processes sensitive to the information carried by the flow of events. The conception of what properties of the conditioned and unconditioned stimuli are important shifts from the tangible properties to the intangible properties of number, duration, frequency and contingency. In this view, a stimulus becomes a CS if its onset substantially reduces the subject's uncertainty about the time of occurrence of the next US. One way to represent the subject's knowledge of that time of occurrence is by the cumulative probability function, which has two limiting forms: (1) The state of maximal uncertainty (minimal knowledge) is represented by the inverse exponential function for the random rate condition, in which the US is equally likely at any moment. (2) The limit to the subject's attainable certainty is represented by the cumulative normal function, whose momentary expectation is the CS-US latency minus the time elapsed since CS onset. Its standard deviation is the Weber fraction times the CS-US latency.

  11. Color consilience: color through the lens of art practice, history, philosophy, and neuroscience.

    PubMed

    Conway, Bevil R

    2012-03-01

    Paintings can be interpreted as the product of the complex neural machinery that translates physical light signals into behavior, experience, and emotion. The brain mechanisms responsible for vision and perception have been sculpted during evolution and further modified by cultural exposure and development. By closely examining artists' paintings and practices, we can discover hints to how the brain works, and achieve insight into the discoveries and inventions of artists and their impact on culture. Here, I focus on an integral aspect of color, color contrast, which poses a challenge for artists: a mark situated on an otherwise blank canvas will appear a different color in the context of the finished painting. How do artists account for this change in color during the production of a painting? In the broader context of neural and philosophical considerations of color, I discuss the practices of three modern masters, Henri Matisse, Paul Cézanne, and Claude Monet, and suggest that the strategies they developed not only capitalized on the neural mechanisms of color, but also influenced the trajectory of western art history. © 2012 New York Academy of Sciences.

  12. Linear and quadratic models of point process systems: contributions of patterned input to output.

    PubMed

    Lindsay, K A; Rosenberg, J R

    2012-08-01

    In the 1880's Volterra characterised a nonlinear system using a functional series connecting continuous input and continuous output. Norbert Wiener, in the 1940's, circumvented problems associated with the application of Volterra series to physical problems by deriving from it a new series of terms that are mutually uncorrelated with respect to Gaussian processes. Subsequently, Brillinger, in the 1970's, introduced a point-process analogue of Volterra's series connecting point-process inputs to the instantaneous rate of point-process output. We derive here a new series from this analogue in which its terms are mutually uncorrelated with respect to Poisson processes. This new series expresses how patterned input in a spike train, represented by third-order cross-cumulants, is converted into the instantaneous rate of an output point-process. Given experimental records of suitable duration, the contribution of arbitrary patterned input to an output process can, in principle, be determined. Solutions for linear and quadratic point-process models with one and two inputs and a single output are investigated. Our theoretical results are applied to isolated muscle spindle data in which the spike trains from the primary and secondary endings from the same muscle spindle are recorded in response to stimulation of one and then two static fusimotor axons in the absence and presence of a random length change imposed on the parent muscle. For a fixed mean rate of input spikes, the analysis of the experimental data makes explicit which patterns of two input spikes contribute to an output spike. Copyright © 2012 Elsevier Ltd. All rights reserved.

  13. Development of a Modular Research Platform to Create Medical Observational Studies for Mobile Devices.

    PubMed

    Zens, Martin; Grotejohann, Birgit; Tassoni, Adrian; Duttenhoefer, Fabian; Südkamp, Norbert P; Niemeyer, Philipp

    2017-05-23

    Observational studies have proven to be a valuable resource in medical research, especially when performed on a large scale. Recently, mobile device-based observational studies have been discovered by an increasing number of researchers as a promising new source of information. However, the development and deployment of app-based studies is not trivial and requires profound programming skills. The aim of this project was to develop a modular online research platform that allows researchers to create medical studies for mobile devices without extensive programming skills. The platform approach for a modular research platform consists of three major components. A Web-based platform forms the researchers' main workplace. This platform communicates via a shared database with a platform independent mobile app. Furthermore, a separate Web-based login platform for physicians and other health care professionals is outlined and completes the concept. A prototype of the research platform has been developed and is currently in beta testing. Simple questionnaire studies can be created within minutes and published for testing purposes. Screenshots of an example study are provided, and the general working principle is displayed. In this project, we have created a basis for a novel research platform. The necessity and implications of a modular approach were displayed and an outline for future development given. International researchers are invited and encouraged to participate in this ongoing project. ©Martin Zens, Birgit Grotejohann, Adrian Tassoni, Fabian Duttenhoefer, Norbert P Südkamp, Philipp Niemeyer. Originally published in JMIR Research Protocols (http://www.researchprotocols.org), 23.05.2017.

  14. Hubble refurbished and ready for release

    NASA Astrophysics Data System (ADS)

    1993-12-01

    ) tomorrow morning. The telescope's aperture door will open just prior to the release. ESA astronaut Claude Nicollier will operate the shuttle's robot arm during the deployment, as he has throughout the lengthy spacewalks and the retrieval of the telescope. This mission has seen more arm operations than any other. Milt Heflin, NASA's lead flight director for the mission, paid tribute to Nicollier at a news conference today. "Claude was magnificent arm driver" he said. "The arm was surgically put in place every time. Folks can be very proud of him". Endeavour is scheduled to return to Earth Monday 13 December.

  15. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lizcano, D., E-mail: david.lizcano@udima.es, E-mail: mariaaurora.martinez@udima.es; Martínez, A. María, E-mail: david.lizcano@udima.es, E-mail: mariaaurora.martinez@udima.es

    Edward Fredkin was an enthusiastic advocate of information-based theoretical physics, who, in the early 1980s, proposed a new theory of physics based on the idea that the universe is ultimately composed of software. According to Fredkin, reality should be considered as being composed not of particles, matter and forces or energy but of bits of data or information modified according to computational rules. Fredkin went on to demonstrate that, while energy is necessary for storing and retrieving information, it can be arbitrarily reduced in order to carry out any particular instance of information processing, and this operation does not havemore » a lower bound. This implies that it is information rather than matter or energy that should be considered at the ultimate fundamental constituent of reality. This possibility had already been suggested by other scientists. Norbert Wiener heralded a fundamental shift from energy to information and suggested that the universe was founded essentially on the transformation of information, not energy. However, Konrad Zuse was the first, back in 1967, to defend the idea that a digital computer is computing the universe. Richard P. Feynman showed this possibility in a similar light in his reflections on how information related to matter and energy. Other pioneering research on the theory of digital physics was published by Kantor in 1977 and more recently by Stephen Wolfram in 2002, who thereby joined the host of voices upholding that it is patterns of information, not matter and energy, that constitute the cornerstones of reality. In this paper, we introduce the use of knowledge management tools for the purpose of analysing this topic.« less

  16. History of diabetes mellitus.

    PubMed

    Ahmed, Awad M

    2002-04-01

    Clinical features similar to diabetes mellitus were described 3000 years ago by the ancient Egyptians. The term "diabetes" was first coined by Araetus of Cappodocia (81-133AD). Later, the word mellitus (honey sweet) was added by Thomas Willis (Britain) in 1675 after rediscovering the sweetness of urine and blood of patients (first noticed by the ancient Indians). It was only in 1776 that Dobson (Britain) firstly confirmed the presence of excess sugar in urine and blood as a cause of their sweetness. In modern time, the history of diabetes coincided with the emergence of experimental medicine. An important milestone in the history of diabetes is the establishment of the role of the liver in glycogenesis, and the concept that diabetes is due to excess glucose production Claude Bernard (France) in 1857. The role of the pancreas in pathogenesis of diabetes was discovered by Mering and Minkowski (Austria) 1889. Later, this discovery constituted the basis of insulin isolation and clinical use by Banting and Best (Canada) in 1921. Trials to prepare an orally administrated hypoglycemic agent ended successfully by first marketing of tolbutamide and carbutamide in 1955. This report will also discuss the history of dietary management and acute and chronic complications of diabetes.

  17. "The Civil Rights Movement of the 1990s?": The anti-abortion movement and the struggle for racial justice.

    PubMed

    Hughes, Richard L

    2006-01-01

    In 1964, Claude and Jeanne Nolen, who were white, joined an interracial NAACP team intent on desegregating local restaurants in Austin, Texas as a test of the recently passed Civil Rights ACt. Twenty-five years later, the Nolens pleaded "no contest" in a courtroom for their continued social activism. This time the issue was not racial segregation, but rather criminal trespassing for blockading abortion clinics with Operation Rescue. The Nolens served prison sentences for direct action protests that they believe stemmed from the same commitment to Christianity and social justice as the civil rights movements. Despite its relationship to political and cultural conservatism, the anti-abortion movement since Roe v. Wade (1973) was also a product of the progressive social movements of the turbulent sixties. Utilizing oral history interviews and organizational literature, the article explores the historical context of the anti-abortion movement, specifically how the lengthy struggle for racial justice shaped the rhetoric, tactics, and ideology of the anti-abortion activists. Even after political conservatives dominated the movement in the 1980s, the successes and failures of the sixties provided a cultural lens through which grassroots anti-abortion activists forged what was arguably the largest movement of civil disobedience in American history.

  18. KSC-99pp1473

    NASA Image and Video Library

    1999-12-19

    Space Shuttle Discovery hurtles through clouds of smoke and steam in its successful launch on mission STS-103. Liftoff occurred at 7:50 p.m. EST from Launch Pad 39B. On board are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland and Jean-François Clervoy of France. Nicollier and Clervoy are with the European Space Agency. STS-103 is a Hubble Servicing Mission, with three planned space walks designed to install new equipment and replace old. The primary objective is to replace the gyroscopes that make up the three Rate Sensor Units. Extravehicular activities include installing a new computer, changing out one of the Fine Guidance Sensors, replacing a tape recorder with a new solid state recorder, and installing a voltage/temperature improvement kit, and begin repairing the insulation on the telescope's outer surface. After the 7-day, 21-hour mission, Discovery is targeted to land at KSC Monday, Dec. 27, at about 5:24 p.m. EST. This is the 27th flight of Discovery and the 96th mission in the Space Shuttle Program. It is the third launch at Kennedy Space Center in 1999

  19. Patent Reform Proposals Raise the Stakes for Researchers, Manufacturers of Biologics

    PubMed Central

    Kravetz, Shayna B.; Frei, Rosemary

    2008-01-01

    When the founding fathers provided for patents in the American Constitution, they could hardly have envisioned the 21st-century demands the U.S. Patents and Trademarks Office (PTO) face today. The PTO is an institution that is, by definition, concerned with the new—one essential element of a patent is novelty; however, it is also struggling to fit the needs of modern biotech research and development within a framework conceived by the young American government in the 18th century. In their new book Biotechnology and the Patent System (AEI Press, Washington, DC, 2007), Claude Barfield, PhD, and John Calfee, PhD, both Resident Scholars at the American Enterprise Institute, Washington, DC, discuss reforms being considered by legislators, lawyers, and members of the biotechnology industry that could modernize the patent system and make it work for all the stakeholders. The proposed reforms include changing the way patent applications are filed and pursued, limiting encumbrances that slow the application process, providing more funding to the PTO to speed consideration of applications, granting interested parties the right to intervene while a patent application is being considered, and limiting the administrative and economic burdens associated with the mushrooming numbers of patents for each product or process. PMID:25126213

  20. Astronomical Dating of Monet's Paintings on the Normandy Coast

    NASA Astrophysics Data System (ADS)

    Olson, D. W.

    2016-01-01

    Claude Monet (1840-1926) is famous for landscapes accurately capturing the changing nature of seas and skies. Monet created almost two thousand paintings during his long career, and several hundred of these works depict the skies above the spectacular cliffs, arches, rocks, harbors, and beaches on the Normandy coast. Our Texas State University group made a research trip to Normandy in the summer of 2012 and found dozens of the locations where Monet set up his easel. Astronomical considerations of daylight, twilight, night skies, and tides can be used to enhance our understanding of the artist's creative process. Monet himself said, “I need the Sun or the cloudy weather to coincide again with the tide, which must be low or high in accordance with my motifs.” Astronomical methods can be used to help in dating these works, many of which have uncertain dates in the existing catalogues and literature about Monet in Normandy. Analysis using the direction of sunlight and the direction of shadows, combined with calculations of lunar phases and tide levels, meteorological records, and the artist's letters, enables us to determine the exact date and the precise time, accurate to the minute, when Monet observed the sky that inspired a painting.

  1. STS-103 Payload Commander Smith and his wife DEPART PAFB for Houston

    NASA Technical Reports Server (NTRS)

    1999-01-01

    STS-103 Payload Commander Steven L. Smith and his wife, Peggy, smile for the camera on the runway at Patrick Air Force Base in Cocoa Beach, Fla. The STS-103 crew and their families are preparing to board an airplane that will return them to their home base at the Johnson Space Center in Houston following the successful completion of their mission. Discovery landed in darkness the previous evening, Dec. 27, on runway 33 at KSC's Shuttle Landing Facility at 7:00:47 p.m. EST. This was the first time that a Shuttle crew spent the Christmas holiday in space. The other STS-103 crew members are Commander Curtis L. Brown Jr.; Pilot Scott J. Kelly; and Mission Specialists C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland and Jean-Frangois Clervoy of France. The STS-103 mission accomplished outfitting the Hubble Space Telescope with six new gyroscopes, six new voltage/temperature improvement kits, a new onboard computer, a new solid state recorder and new data transmitter, a new fine guidance sensor along with new insulation on parts of the orbiting telescope. This was the 96th flight in the Space Shuttle program and the 27th for the orbiter Discovery.

  2. STS-103 Pilot Kelly and MS Clervoy and Smith DEPART PAFB for Houston

    NASA Technical Reports Server (NTRS)

    1999-01-01

    STS-103 Pilot Scott J. Kelly holds his daughter as he talks to Mission Specialists and fellow crew members Jean-Frangois Clervoy of France and Steven L. Smith on the runway at Patrick Air Force Base in Cocoa Beach, Fla. The STS-103 crew and their families are preparing to board an airplane that will return them to their home base at the Johnson Space Center in Houston following the successful completion of their mission. Discovery landed in darkness the previous evening, Dec. 27, on runway 33 at KSC's Shuttle Landing Facility at 7:00:47 p.m. EST. This was the first time that a Shuttle crew spent the Christmas holiday in space. The other STS-103 crew members are Commander Curtis L. Brown Jr. and Mission Specialists C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), and Claude Nicollier of Switzerland. The STS-103 mission accomplished outfitting the Hubble Space Telescope with six new gyroscopes, six new voltage/temperature improvement kits, a new onboard computer, a new solid state recorder and new data transmitter, a new fine guidance sensor along with new insulation on parts of the orbiting telescope. This was the 96th flight in the Space Shuttle program and the 27th for the orbiter Discovery.

  3. Vascular access: an historical perspective from Sir William Harvey to the 1956 Nobel prize to André F. Cournand, Werner Forssmann, and Dickinson W. Richards.

    PubMed

    Sette, Piersandro; Dorizzi, Romolo M; Azzini, Anna M

    2012-01-01

    Sir William Harvey (1578-1657), who had many precursors, discovered blood circulation in 1628 after a significant number of anatomic dissection of cadavers; his studies were continued by Sir Christopher Wren and Daniel Johann Major. The first central vein catheterization was performed on a horse by Stephen Hales, an English Vicar. In 1844, a century later, the French biologist Claude Bernard attempted the first carotid artery cannulation and repeated the procedure in the jugular vein, again on a horse. He was first to report the complications now well known to be associated with this maneuver. In 1929 Werner Forssmann tried cardiac catheterization on himself, but could not investigate the procedure further since his findings were rejected and ridiculed by colleagues. His work was continued by André Frédéric Cournand and Dickinson Woodruff Richards Jr in the United States. In 1956 the three physicians shared the Nobel Prize for Medicine for their studies on vascular and cardiac systems. The genius and the perseverance of the three physicians paved the way towards peripheral and central catheter vein placement, one of the most frequently performed maneuvers in hospitals. Its history still remains unknown to most and deserves a short description.

  4. The origins, early development and status of Bourdieu's concept of 'cultural capital'.

    PubMed

    Robbins, Derek

    2005-03-01

    The paper examines the context of the first introduction of the concept of 'cultural capital' in the sociology of education analyses undertaken in the early 1960s and published by Bourdieu in collaboration with Jean-Claude Passeron in 'Les etudiants et leurs etudes' (1964a) and Les Heritiers (1964b). It first considers the cultural contexts within which Bourdieu's thinking about culture originated--both in relation to his social origins and in relation to his intellectual training. It then examines the extent to which Bourdieu's early anthropological research in Algeria was influenced by his knowledge of American acculturation theory. It concludes that Bourdieu sought to use acculturation theory in a distinctive way--one which he articulated more confidently as he explored the relationship between agency and structural explanation in the late 1960s and early 1970s. The specific educational researches which stimulated the articulation of the concept of 'linguistic' or 'cultural' capital belonged to the period in which Bourdieu was only just beginning to refine his post-structuralist philosophy of social scientific explanation. To use these concepts now involves deploying them reflexively in accordance with Bourdieu's later thinking rather than at face value as they were first developed during the period in which he and Passeron were 'apprentice' researchers.

  5. STS-103 Mission Highlights Resource Tape (1 of 2)

    NASA Technical Reports Server (NTRS)

    2000-01-01

    The STS-103 flight crew, Commander Curtis L. Brown, Pilot Scott J. Kelly, Mission Specialists Steven L. Smith, C. Michael Foale, John M. Grunsfeld, Claude Nicollier, and Jean-Francois Clervoy, are seen performing pre-launch activities such as crew suit-up, and ride out to the launch pad for a night launch. Also, included are various panoramic views of the shuttle on the pad. The crew is readied in the White Room for their mission. After the closing of the hatch and arm retraction, launch activities are shown including countdown, engine ignition, launch, and the separation of the Solid Rocket Boosters. Once on-orbit the primary objective is to capture and service the Hubble Space Telescope. Included are various live shots of the payload bay showing the flight support system, the orbiter replacement unit carrier and the forward fixture that house the new Fine Guidance System (FGS). Smith and Grunsfeld replaces and changes the sensor units during the first space walk of this mission. The second space walk by Nicollier and Foale includes the changing of the computer and installation of the FGS. This is tape 1 of 2, tape 2 has a report number of NONP-NASA-VT-2000036031.

  6. Hubble peeks at a spiral galaxy

    NASA Image and Video Library

    2015-07-10

    This little-known galaxy, officially named J04542829-6625280, but most often referred to as LEDA 89996, is a classic example of a spiral galaxy. The galaxy is much like our own galaxy, the Milky Way. The disk-shaped galaxy is seen face on, revealing the winding structure of the spiral arms. Dark patches in these spiral arms are in fact dust and gas — the raw materials for new stars. The many young stars that form in these regions make the spiral arms appear bright and bluish. The galaxy sits in a vibrant area of the night sky within the constellation of Dorado (The Swordfish), and appears very close to the Large Magellanic Cloud — one of the satellite galaxies of the Milky Way. The observations were carried out with the high resolution channel of Hubble’s Advanced Camera for Surveys. Image credit: ESA/Hubble & NASA, Acknowledgement: Flickr user C. Claude NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

  7. Spatio-temporal regulation of connexin43 phosphorylation and gap junction dynamics.

    PubMed

    Solan, Joell L; Lampe, Paul D

    2018-01-01

    Gap junctions are specialized membrane domains containing tens to thousands of intercellular channels. These channels permit exchange of small molecules (<1000Da) including ions, amino acids, nucleotides, metabolites and secondary messengers (e.g., calcium, glucose, cAMP, cGMP, IP 3 ) between cells. The common reductionist view of these structures is that they are composed entirely of integral membrane proteins encoded by the 21 member connexin human gene family. However, it is clear that the normal physiological function of this structure requires interaction and regulation by a variety of proteins, especially kinases. Phosphorylation is capable of directly modulating connexin channel function but the most dramatic effects on gap junction activity occur via the organization of the gap junction structures themselves. This is a direct result of the short half-life of the primary gap junction protein, connexin, which requires them to be constantly assembled, remodeled and turned over. The biological consequences of this remodeling are well illustrated during cardiac ischemia, a process wherein gap junctions are disassembled and remodeled resulting in arrhythmia and ultimately heart failure. This article is part of a Special Issue entitled: Gap Junction Proteins edited by Jean Claude Herve. Copyright © 2017 Elsevier B.V. All rights reserved.

  8. EU to review implications of tax

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Scott, A.

    1997-05-21

    The European Council of Ministers has postponed discussion of the European Commission`s proposed energy tax and has authorized a study to reevaluate the technical and legal implications and the costs and benefits of the tax. The reevaluation comes as a ray of hope to European chemical industry officials, who are concerned about the effects of the tax on the industry`s international competitiveness. The commission`s proposal would tax natural gas, electricity, and coal in the European Union (EU) for the first time. It would raise taxes throughout the EU to one level. In its current form the energy tax would devastatemore » the European industry`s competitiveness outside the region, says European Chemical Industry Council (Cefic) counsel Claude Culem. We`re willing to improve emissions to achieve environmental goals - we don`t need energy taxes, Culem tells CW. The whole project is dangerous, not necessarily in the short term, but certainly in the long term. European Parliament ministers are scheduled to debate the issue with the Dutch government, which holds the EU presidency, and hope to wrap up proceedings over the summer. The tax may only be adopted when ministers agree on it unanimously. If it is approved, it would be implemented in two stages, in 2000 and 2002.« less

  9. Mathematical modeling of a Fermilab helium liquefier coldbox

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Geynisman, M.G.; Walker, R.J.

    1995-12-01

    Fermilab Central Helium Liquefier (CHL) facility is operated 24 hours-a-day to supply 4.6{degrees}K for the Fermilab Tevatron superconducting proton-antiproton collider Ring and to recover warm return gases. The centerpieces of the CHL are two independent cold boxes rated at 4000 and 5400 liters/hour with LN{sub 2} precool. These coldboxes are Claude cycle and have identical heat exchangers trains, but different turbo-expanders. The Tevatron cryogenics demand for higher helium supply from CHL was the driving force to investigate an installation of an expansion engine in place of the Joule-Thompson valve. A mathematical model was developed to describe the thermo- and gas-dynamicmore » processes for the equipment included in the helium coldbox. The model is based on a finite element approach, opposite to a global variables approach, thus providing for higher accuracy and conversion stability. Though the coefficients used in thermo- and gas-dynamic equations are unique for a given coldbox, the general approach, the equations, the methods of computations, and most of the subroutines written in FORTRAN can be readily applied to different coldboxes. The simulation results are compared against actual operating data to demonstrate applicability of the model.« less

  10. Cryogenics for the MuCool Test Area (MTA)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Darve, Christine; Norris, Barry; Pei, Liu-Jin

    2005-09-01

    MuCool Test Area (MTA) is a complex of buildings at Fermi National Accelerator Laboratory, which are dedicated to operate components of a cooling cell to be used for Muon Collider and Neutrino Factory R&D. The long-term goal of this facility is to test ionization cooling principles by operating a 25-liter liquid hydrogen (LH{sub 2}) absorber embedded in a 5 Tesla superconducting solenoid magnet. The MTA solenoid magnet will be used with RF cavities exposed to a high intensity beam. Cryogens used at the MTA include LHe, LN{sub 2} and LH{sub 2}. The latter dictates stringent system design for hazardous locations.more » The cryogenic plant is a modified Tevatron refrigerator based on the Claude cycle. The implementation of an in-house refrigerator system and two 300 kilowatt screw compressors is under development. The helium refrigeration capacity is 500 W at 14 K. In addition the MTA solenoid magnet will be batch-filled with LHe every 2 days using the same cryo-plant. This paper reviews cryogenic systems used to support the Muon Collider and Neutrino Factory R&D programs and emphasizes the feasibility of handling cryogenic equipment at MTA in a safe manner.« less

  11. Development of the oil-water monitor

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Swanson, C.

    1990-04-02

    The oil-water monitor is a device invented by Dr. Claude Swanson of Applied Physics Technology to respond to the petroleum-loss problem in crude oil transfers. It is a device which measures water content in crude oil and other petroleum products, in a flowing pipe such as a pipeline or tanker manifold. It is capable of accurately measuring the water contamination levels in crude oil shipments, in real time as the crude oil flows through the loading manifold into the tanker, or at the receiving point as the oil is off-loaded It has application in the verification of oil volumes andmore » concentration of contaminants at petroleum transfer points. The industry-estimated level of water loss at transfer points due to inadequate monitoring technology amounts to several billion dollars per year, so there is a definite perceived need within the petroleum community for this type of accurate water monitoring technology. The device has been patented, and initial feasibility experiments have been conducted. The present research is directed toward developing and demonstrating a bench model prototype of the oil-water monitor, complete with the computer software and automated microwave equipment and electronics which will demonstrate the performance of the invention, for implementation in full-scale fielded systems. 3 figs.« less

  12. Cryogenics for the MuCool Test Area (MTA)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Darve, Christine; Norris, Barry; Pei, Liujin

    2006-03-20

    MuCool Test Area (MTA) is a complex of buildings at Fermi National Accelerator Laboratory, which are dedicated to operate components of a cooling cell to be used for Muon Collider and Neutrino Factory R and D. The long-term goal of this facility is to test ionization cooling principles by operating a 25-liter liquid hydrogen (LH2) absorber embedded in a 5 Tesla superconducting solenoid magnet. The MTA solenoid magnet will be used with RF cavities exposed to a high intensity beam. Cryogens used at the MTA include LHe, LN2 and LH2. The latter dictates stringent system design for hazardous locations. Themore » cryogenic plant is a modified Tevatron refrigerator based on the Claude cycle. The implementation of an in-house refrigerator system and two 300 kilowatt screw compressors is under development. The helium refrigeration capacity is 500 W at 14 K. In addition the MTA solenoid magnet will be batch-filled with LHe every 2 days using the same cryo-plant. This paper reviews cryogenic systems used to support the Muon Collider and Neutrino Factory R and D programs and emphasizes the feasibility of handling cryogenic equipment at MTA in a safe manner.« less

  13. A physiologist's view of homeostasis

    PubMed Central

    Cliff, William; Michael, Joel; McFarland, Jenny; Wenderoth, Mary Pat; Wright, Ann

    2015-01-01

    Homeostasis is a core concept necessary for understanding the many regulatory mechanisms in physiology. Claude Bernard originally proposed the concept of the constancy of the “milieu interieur,” but his discussion was rather abstract. Walter Cannon introduced the term “homeostasis” and expanded Bernard's notion of “constancy” of the internal environment in an explicit and concrete way. In the 1960s, homeostatic regulatory mechanisms in physiology began to be described as discrete processes following the application of engineering control system analysis to physiological systems. Unfortunately, many undergraduate texts continue to highlight abstract aspects of the concept rather than emphasizing a general model that can be specifically and comprehensively applied to all homeostatic mechanisms. As a result, students and instructors alike often fail to develop a clear, concise model with which to think about such systems. In this article, we present a standard model for homeostatic mechanisms to be used at the undergraduate level. We discuss common sources of confusion (“sticky points”) that arise from inconsistencies in vocabulary and illustrations found in popular undergraduate texts. Finally, we propose a simplified model and vocabulary set for helping undergraduate students build effective mental models of homeostatic regulation in physiological systems. PMID:26628646

  14. STS-103 Mission Specialist Grunsfeld and his family DEPART PAFB for Houston

    NASA Technical Reports Server (NTRS)

    1999-01-01

    STS-103 Mission Specialist John M. Grunsfeld (Ph.D.), with his wife, Carol, and their children, smiles for the camera on the runway at Patrick Air Force Base in Cocoa Beach, Fla. The STS-103 crew and their families are preparing to board an airplane that will return them to their home base at the Johnson Space Center in Houston following the successful completion of their mission. Discovery landed in darkness the previous evening, Dec. 27, on runway 33 at KSC's Shuttle Landing Facility at 7:00:47 p.m. EST. This was the first time that a Shuttle crew spent the Christmas holiday in space. The other STS-103 crew members are Commander Curtis L. Brown Jr.; Pilot Scott J. Kelly; and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), Claude Nicollier of Switzerland and Jean-Frangois Clervoy of France. The STS-103 mission accomplished outfitting the Hubble Space Telescope with six new gyroscopes, six new voltage/temperature improvement kits, a new onboard computer, a new solid state recorder and new data transmitter, a new fine guidance sensor along with new insulation on parts of the orbiting telescope. This was the 96th flight in the Space Shuttle program and the 27th for the orbiter Discovery.

  15. STS-103 crew members and their families pose for a portrait before DEPARTing

    NASA Technical Reports Server (NTRS)

    1999-01-01

    The STS-103 crew pose for a group portrait with their families and loved ones on the runway at Patrick Air Force Base in Cocoa Beach, Fla. They are preparing to board an airplane that will return them to their home base at the Johnson Space Center in Houston following the successful completion of their mission. From left to right, the crew members are Mission Specialists John M. Grunsfeld (Ph.D.), C. Michael Foale (Ph.D.), Claude Nicollier of Switzerland, Jean-Frangois Clervoy of France, and Steven L. Smith; Pilot Scott J. Kelly; and Commander Curtis L. Brown Jr. Discovery landed in darkness the previous evening, Dec. 27, on runway 33 at KSC's Shuttle Landing Facility at 7:00:47 p.m. EST. This was the first time that a Shuttle crew spent the Christmas holiday in space. The STS-103 mission accomplished outfitting the Hubble Space Telescope with six new gyroscopes, six new voltage/temperature improvement kits, a new onboard computer, a new solid state recorder and new data transmitter, a new fine guidance sensor along with new insulation on parts of the orbiting telescope. This was the 96th flight in the Space Shuttle program and the 27th for the orbiter Discovery.

  16. STS-103 Mission Specialist Foale and his family DEPART PAFB for Houston

    NASA Technical Reports Server (NTRS)

    1999-01-01

    STS-103 Mission Specialist C. Michael Foale (Ph.D.) holds one of his children on the runway at Patrick Air Force Base in Cocoa Beach, Fla., as his wife, Rhonda, looks on. The STS-103 crew and their families are preparing to board an airplane that will return them to their home base at the Johnson Space Center in Houston following the successful completion of their mission. Discovery landed in darkness the previous evening, Dec. 27, on runway 33 at KSC's Shuttle Landing Facility at 7:00:47 p.m. EST. This was the first time that a Shuttle crew spent the Christmas holiday in space. The other STS-103 crew members are Commander Curtis L. Brown Jr.; Pilot Scott J. Kelly; and Mission Specialists Steven L. Smith, John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland and Jean-Frangois Clervoy of France. The STS-103 mission accomplished outfitting the Hubble Space Telescope with six new gyroscopes, six new voltage/temperature improvement kits, a new onboard computer, a new solid state recorder and new data transmitter, a new fine guidance sensor along with new insulation on parts of the orbiting telescope. This was the 96th flight in the Space Shuttle program and the 27th for the orbiter Discovery.

  17. Defining the factors that affect solute permeation of gap junction channels.

    PubMed

    Valiunas, Virginijus; Cohen, Ira S; Brink, Peter R

    2018-01-01

    This review focuses on the biophysical properties and structure of the pore and vestibule of homotypic gap junction channels as they relate to channel permeability and selectivity. Gap junction channels are unique in their sole role to connect the cytoplasm of two adjacent cells. In general, these channels are considered to be poorly selective, possess open probabilities approximating unity, and exhibit mean open times ranging from milliseconds to seconds. These properties suggest that such channels can function as delivery pathways from cell to cell for solutes that are significantly larger than monovalent ions. We have taken quantitative data from published works concerning unitary conductance, ion flux, and permeability for homotypic connexin 43 (Cx43), Cx40, Cx26, Cx50, and Cx37, and performed a comparative analysis of conductance and/or ion/solute flux versus diffusion coefficient. The analysis of monovalent cation flux portrays the pore as equivalent to an aqueous space where hydrogen bonding and weak interactions with binding sites dominate. For larger solutes, size, shape and charge are also significant components in determining the permeation rate. This article is part of a Special Issue entitled: Gap Junction Proteins edited by Jean Claude Herve. Copyright © 2017 Elsevier B.V. All rights reserved.

  18. Narrating consciousness: language, media and embodiment.

    PubMed

    Hayles, N Katherine; Pulizzi, James J

    2010-01-01

    Although there has long been a division in studies of consciousness between a focus on neuronal processes or conversely an emphasis on the ruminations of a conscious self, the long-standing split between mechanism and meaning within the brain was mirrored by a split without, between information as a technical term and the meanings that messages are commonly thought to convey. How to heal this breach has posed formidable problems to researchers. Working through the history of cybernetics, one of the historical sites where Claude Shannon's information theory quickly became received doctrine, we argue that the cybernetic program as it developed through second-order cybernetics and autopoietic theory remains incomplete. In this article, we return to fundamental questions about pattern and noise, context and meaning, to forge connections between consciousness, narrative and media. The thrust of our project is to reintroduce context and narrative as crucial factors in the processes of meaning-making. The project proceeds along two fronts: advancing a theoretical framework within which context plays its property central role; and demonstrating the importance of context by analyzing two fictions, Stanislaw Lem's "His Master's Voice" and Joseph McElroy's "Plus," in which context has been deformed by being wrenched away from normal human environments, with radical consequences for processes of meaning-making.

  19. Galaxy with a view

    NASA Image and Video Library

    2015-07-06

    This little-known galaxy, officially named J04542829-6625280, but most often referred to as LEDA 89996, is a classic example of a spiral galaxy. The galaxy is much like our own galaxy, the Milky Way. The disc-shaped galaxy is seen face on, revealing the winding structure of the spiral arms. Dark patches in these spiral arms are in fact dust and gas — the raw materials for new stars. The many young stars that form in these regions make the spiral arms appear bright and bluish. The galaxy sits in a vibrant area of the night sky within the constellation of Dorado (The Swordfish), and appears very close to the Large Magellanic Cloud  — one of the satellite galaxies of the Milky Way. The observations were carried out with the high resolution channel of Hubble’s Advanced Camera for Surveys. This instrument has delivered some of the sharpest views of the Universe so far achieved by mankind. This image covers only a tiny patch of sky — about the size of a one cent euro coin held 100 metres away! A version of this image was entered into the Hubble’s Hidden Treasures image processing competition by flickr user c.claude.

  20. STS-75 Flight Day 1

    NASA Technical Reports Server (NTRS)

    1996-01-01

    On this first day of the STS-75 mission, the flight crew, Cmdr. Andrew Allen, Pilot Scott Horowitz, Payload Cmdr. Franklin Chang-Diaz, Payload Specialist Umberto Guidoni (Italy), and Mission Specialists Jeffrey Hoffman, Maurizio Cheli (ESA) and Claude Nicollier (ESA), were shown performing pre-launch and launching activities. This international space mission's primary objective is the deployment of the Tethered Satellite System Reflight (TSS-1R) to a 12 mile length from the shuttle, a variety of experiments, and the satellite retrieval. These experiments include: Research on Orbital Plasma Electrodynamics (ROPE); TSS Deployer Core Equipment and Satellite Core Equipment (DCORE/SCORE); Research on Electrodynamic Tether Effects (RETE); Magnetic Field Experiments for TSS Missions (TEMAG); Shuttle Electrodynamic Tether Systems (SETS); Shuttle Potential and Return Electron Experiment (SPREE); Tether Optical Phenomena Experiment (TOP); and Observations at the Earth's Surface of Electromagnetic Emissions by TSS (OESSE). The mission's secondary objectives were those experiments found in the United States Microgravity Payload-3 (USMP-3), which include: Advanced Automated Directional Solidification Furnace (AADSF); Material pour l'Etude des Phenomenes Interessant la Solidification sur Terre et en Orbite (MEPHISTO); Space Acceleration Measurement System (SAMS); Orbital Acceleration Research Experiment (OARE); Critical Fluid Scattering Experiment (ZENO); and Isothermal Dendritic Growth Experiment (IDGE).

  1. Patent reform proposals raise the stakes for researchers, manufacturers of biologics.

    PubMed

    Kravetz, Shayna B; Frei, Rosemary

    2008-03-01

    When the founding fathers provided for patents in the American Constitution, they could hardly have envisioned the 21st-century demands the U.S. Patents and Trademarks Office (PTO) face today. The PTO is an institution that is, by definition, concerned with the new-one essential element of a patent is novelty; however, it is also struggling to fit the needs of modern biotech research and development within a framework conceived by the young American government in the 18th century. In their new book Biotechnology and the Patent System (AEI Press, Washington, DC, 2007), Claude Barfield, PhD, and John Calfee, PhD, both Resident Scholars at the American Enterprise Institute, Washington, DC, discuss reforms being considered by legislators, lawyers, and members of the biotechnology industry that could modernize the patent system and make it work for all the stakeholders. The proposed reforms include changing the way patent applications are filed and pursued, limiting encumbrances that slow the application process, providing more funding to the PTO to speed consideration of applications, granting interested parties the right to intervene while a patent application is being considered, and limiting the administrative and economic burdens associated with the mushrooming numbers of patents for each product or process.

  2. The AGING Initiative experience: a call for sustained support for team science networks.

    PubMed

    Garg, Tullika; Anzuoni, Kathryn; Landyn, Valentina; Hajduk, Alexandra; Waring, Stephen; Hanson, Leah R; Whitson, Heather E

    2018-05-18

    Team science, defined as collaborative research efforts that leverage the expertise of diverse disciplines, is recognised as a critical means to address complex healthcare challenges, but the practical implementation of team science can be difficult. Our objective is to describe the barriers, solutions and lessons learned from our team science experience as applied to the complex and growing challenge of multiple chronic conditions (MCC). MCC is the presence of two or more chronic conditions that have a collective adverse effect on health status, function or quality of life, and that require complex healthcare management, decision-making or coordination. Due to the increasing impact on the United States society, MCC research has been identified as a high priority research area by multiple federal agencies. In response to this need, two national research entities, the Healthcare Systems Research Network (HCSRN) and the Claude D. Pepper Older Americans Independence Centers (OAIC), formed the Advancing Geriatrics Infrastructure and Network Growth (AGING) Initiative to build nationwide capacity for MCC team science. This article describes the structure, lessons learned and initial outcomes of the AGING Initiative. We call for funding mechanisms to sustain infrastructures that have demonstrated success in fostering team science and innovation in translating findings to policy change necessary to solve complex problems in healthcare.

  3. Application of Semi-Definite Programming for Many-Fermion Systems

    NASA Astrophysics Data System (ADS)

    Zhao, Zhengji; Braams, Bastiaan; Fukuda, Mituhiro; Overton, Michael

    2003-03-01

    The ground state energy and other important observables of a many-fermion system with one- and two-body interactions only can all be obtained from the first order and second order Reduced Density Matrices (RDM's) of the system. Using these density matrices and a family of associated representability conditions one may obtain an approximation method for electronic structure theory that is in the mathematical form of Semi-Definite Programming (SDP): minimize a linear matrix functional over a space of positive semidefinite matrices subject to linear constraints. The representability conditions are some known necessary conditions, starting with the well-known P, Q, and G conditions [Claude Garrod and Jerome K. Percus, Reducation of the N-Particle Variational Problem, J. Math. Phys. 5 (1964) 1756-1776]. The RDM method with SDP has great potential advantages over the wave function method when the particle number N is large. The dimension of the full configuration space increases exponentially with N, but in RDM method with SDP the dimension of the objective matrix (which includes RDM's) increases only polynomially with N. We will report on the effect of adding the generalized three-index conditions proposed in [R. M. Erdahl, Representability, Int. J. Quantum Chem. 13 (1978) 697-718].

  4. Exploring forward physics with the PHENIX MPC-EX upgrade

    NASA Astrophysics Data System (ADS)

    Novitzky, Norbert; Phenix Collaboration

    2014-09-01

    The MPC-EX detector is a Si-W preshower extension to the existing Muon Piston Calorimeter (MPC) at PHENIX. Located at forward rapidity, 3 . 1 < | η | < 3 . 8 , the MPC-EX consists of eight layers of alternating W absorber and Si minipad sensors. Covering a large range at forward rapidity makes the MPC-EX and MPC ideal to access low-x partons in the A nucleus of p + A collisions. The neutral pion and direct photon are excellent probes to separate between the initial and final state effects of the pA collisions. Isolating the direct photon signal requires the MPC-EX to be able to distinguish single showers from double showers. The single versus double shower separation was tested with an electron beam at the SLAC test beam facility. Results from the test beam data will be presented in this talk. The MPC-EX detector is a Si-W preshower extension to the existing Muon Piston Calorimeter (MPC) at PHENIX. Located at forward rapidity, 3 . 1 < | η | < 3 . 8 , the MPC-EX consists of eight layers of alternating W absorber and Si minipad sensors. Covering a large range at forward rapidity makes the MPC-EX and MPC ideal to access low-x partons in the A nucleus of p + A collisions. The neutral pion and direct photon are excellent probes to separate between the initial and final state effects of the pA collisions. Isolating the direct photon signal requires the MPC-EX to be able to distinguish single showers from double showers. The single versus double shower separation was tested with an electron beam at the SLAC test beam facility. Results from the test beam data will be presented in this talk. Norbert Novitzky for PHENIX collaboration.

  5. Water security and societal impacts of tropical cyclones in northwestern Mexico, 1970-2010

    NASA Astrophysics Data System (ADS)

    Scott, C. A.; Farfan, L.

    2012-12-01

    Mexico.Norbert Impacts in Alamos, Sonora, 12 Oct. 2008

  6. "Back on Track": A Mobile App Observational Study Using Apple's ResearchKit Framework.

    PubMed

    Zens, Martin; Woias, Peter; Suedkamp, Norbert P; Niemeyer, Philipp

    2017-02-28

    In March 2015, Apple Inc announced ResearchKit, a novel open-source framework intended to help medical researchers to easily create apps for medical studies. With the announcement of this framework, Apple presented 5 apps built in a beta phase based on this framework. The objective of this study was to better understand decision making in patients with acute anterior cruciate ligament (ACL) ruptures. Here, we describe the development of a ResearchKit app for this study. A multilanguage observatory study was conducted. At first a suitable research topic, target groups, participating territories, and programming method were carefully identified. The ResearchKit framework was used to program the app. A secure server connection was realized via Secure Sockets Layer. A data storage and security concept separating personal information and study data was proposed. Furthermore, an efficient method to allow multilanguage support and distribute the app in many territories was presented. Ethical implications were considered and taken into account regarding privacy policies. An app study based on ResearchKit was developed without comprehensive iPhone Operating System (iOS) development experience. The Apple App Store is a major distribution channel causing significant download rates (>1.200/y) without active recruitment. Preliminary data analysis showed moderate dropout rates and a good quality of data. A total of 180 participants were currently enrolled with 107 actively participating and producing 424 completed surveys in 9 out of 24 months. ResearchKit is an easy-to-use framework and powerful tool to create medical studies. Advantages are the modular built, the extensive reach of iOS devices, and the convenient programming environment. ©Martin Zens, Peter Woias, Norbert P Suedkamp, Philipp Niemeyer. Originally published in JMIR Mhealth and Uhealth (http://mhealth.jmir.org), 28.02.2017.

  7. Linear and nonlinear dynamics of liquid planetary cores

    NASA Astrophysics Data System (ADS)

    Lathrop, D. P.

    2013-12-01

    This is the 50th anniversary of Ed Lorenz brilliant paper "Deterministic Nonperiodic Flow.'' Lorenz's work, along with many other founders' efforts, gave rise to the study of nonlinear dynamics. That field has allowed us to move beyond simple linear characterizations of nature, and to open up a deeper understanding of the Earth, other planets, and stars. Of the many things that make the Earth a habitable home, one is the existence of a planetary magnetic field generated in our liquid iron outer core. The generation process is known to be strongly nonlinear, and thereby almost certainly turbulent. Yet it is not a simple homogeneous isotropic turbulent flow, but is instead heavily modified by rotation and magnetic forces. We attempt to better understand the Earth's core using a three-meter liquid sodium laboratory model of the core. Our work in sodium in this system has just begun. The system exhibits a variety of behaviors with at least twelve different states, drawing different amounts of power, and causing varying levels of magnetic field amplification. In some states, rotation and magnetic fields cause the dynamics to simplify relative to more general turbulent flows in comparable conditions. Acknowledgements: I gratefully acknowledge my collaborators Daniel Zimmerman, Santiago Triana, Donald Martin, Nolan Balew, Henri-Claude Nataf, and Barbara Brawn-Cinani, and funding from the National Science Foundation Earth Sciences Instrumentation and Geophysics programs.

  8. The accentuation principle of figure-ground segregation and the downbeat illusion.

    PubMed

    Pinna, Baingio; Sirigu, Luca

    2016-10-01

    Pinna and Sirigu (2011) demonstrated a new principle of grouping, called the accentuation principle, stating that, all else being equal, elements tend to group in the same oriented direction of the discontinuous element placed within a whole set of continuous/homogeneous components. The discontinuous element behaves like an accent, i.e. a visual emphasis within the wholeness of components as shown in the next section. In this work, the accentuation principle has been extended to new visual domains. In particular, it is shown how this principle affects shape perception. Moreover several visual object attributes are also highlighted, among which orientation, spatial position, inner dynamics and apparent motion that determine the so-called organic segmentation and furthermore tend to induce figure-ground segregation. On the basis of the results of experimental phenomenology, the accentuation can be considered as a complex principle ruling grouping, figure-ground segregation, shape and meaning formation. Through a new musical illusion of downbeat, it is also demonstrated that this principle influences perceptual organization not only in space but also in time and, thus, in both visual and musical domains. This illusion can be heard in eight measures of Pagodes, a solo piano music by Claude Debussy (1862-1918), where a strong physical-perceptual discrepancy in terms of upbeats and downbeats inversion is strongly perceived in both staves. Copyright © 2016 Elsevier B.V. All rights reserved.

  9. KSC-99pp1474

    NASA Image and Video Library

    1999-12-19

    Turning night into day for a few moments while belching clouds of smoke and steam, Space Shuttle Discovery hurtles into the black sky on mission STS-103. The successful liftoff occurred at 7:50 p.m. EST from Launch Pad 39B. On board are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland and Jean-François Clervoy of France. Nicollier and Clervoy are with the European Space Agency. STS-103 is a Hubble Servicing Mission, with three planned space walks designed to install new equipment and replace old. The primary objective is to replace the gyroscopes that make up the three Rate Sensor Units. Extravehicular activities include installing a new computer, changing out one of the Fine Guidance Sensors, replacing a tape recorder with a new solid state recorder, and installing a voltage/temperature improvement kit, and begin repairing the insulation on the telescope's outer surface. After the 7-day, 21-hour mission, Discovery is targeted to land at KSC Monday, Dec. 27, at about 5:24 p.m. EST. This is the 27th flight of Discovery and the 96th mission in the Space Shuttle Program. It is the third launch at Kennedy Space Center in 1999

  10. A plea for "variational neuroethology". Comment on "Answering Schrödinger's question: A free-energy formulation" by M.J. Desormeau Ramstead et al.

    NASA Astrophysics Data System (ADS)

    Daunizeau, Jean

    2018-03-01

    What is life? According to Erwin Schrödinger [13], the living cell departs from other physical systems in that it - apparently - resists the second law of thermodynamics by restricting the dynamical repertoire (minimizing the entropy) of its physiological states. This is a physical rephrasing of Claude Bernard's biological notion of homeostasis, namely: the capacity of living systems to self-organize in order to maintain the stability of their internal milieu despite uninterrupted exchanges with an ever-altering external environment [2]. The important point here is that physical systems can neither identify nor prevent a state of high entropy. The Free Energy Principle or FEP was originally proposed as a mathematical description of how the brain actually solves this issue [4]. In line with the Bayesian brain hypothesis, the FEP views the brain as a hierarchical statistical learning machine, endowed with the imperative of minimizing Free Energy, i.e. prediction error. Action prescription under the FEP, however, does not follow standard Bayesian decision theory. Rather, action is assumed to further minimize Free Energy, which makes the active brain a self-fulfilling prophecy machine [6]. This is adaptive, under the assumption that evolution has equipped the brain with innate priors centered on homeostatic set points. In turn, avoiding (surprising) violations of such prior predictions implements homeostatic regulation [10], which becomes increasingly anticipatory as learning unfolds over the course of ontological development [5].

  11. Monet's Painting under the Microscope

    NASA Astrophysics Data System (ADS)

    Dredge, Paula; Wuhrer, Richard; Phillips, Matthew R.

    2003-04-01

    An oil painting by Claude Monet, Port-Goulphar, Belle-Ile 1887 (collection of the Art Gallery of New South Wales), was examined to determine both the identity of the pigments used by the artist in this painting and his technique of mixing colors and laying paint on the canvas. The extremely complex construction of the painting was revealed by optical microscopy, scanning electron microscopy (SEM), energy dispersive X-ray analysis (EDS), and X-ray mapping (XRM) analysis of cross sections of paint flakes excised from damaged regions of Port-Goulphar, Belle-Ile. Nine different pigments were found on the painting. Many of the identified colors were modern pigments that became available only late in the 19th century as a result of scientific advances in pigment chemistry. Although similar colors were available in a natural mineral form, they lacked the vivid color of their manufactured counterparts. The use of these new synthetic metallic oxide colors by Monet accounts for the brilliance of his paintings. In addition, a separation between successive paint layers was observed in some areas of paint chip cross sections, indicating that oil-based paint was applied to paint that had dried, and consequently, Port-Goulphar, Belle-Ile was painted over a long period of time. This observation is contrary to the general perception of Monet's technique of painting freely and quickly.

  12. STS-103 crew take part in CEIT

    NASA Technical Reports Server (NTRS)

    1999-01-01

    In the Payload Hazardous Servicing Facility, the STS-103 crew look over equipment to be used during their mission. The seven-member crew, taking part in a Crew Equipment Interface Test, are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland, and Jean-Frangois Clervoy of France. Nicollier and Clervoy are with the European Space Agency. Mission STS-103 is a 'call-up' due to the need to replace portions of the pointing system, the gyros, which have begun to fail on the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. The gyroscopes allow the telescope to point at stars, galaxies and planets. The STS-103 crew will not only replace gyroscopes, it will also replace a Fine Guidance Sensor and an older computer with a new enhanced model, an older data tape recorder with a solid state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. The scheduled launch date in October is under review.

  13. KSC-99pp1509

    NASA Image and Video Library

    1999-12-27

    After landing at the Shuttle Landing Facility, STS-103 Pilot Scott J. Kelly (left) and Commander Curtis L. Brown Jr. (right) look at the tiles on orbiter Discovery. They and other crew members Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Jean-Francois Clervoy of France and Claude Nicollier of Switzerland, completed a successful eight-day mission to service the Hubble Space Telescope, spending the Christmas holiday in space in order to accomplish their mission before the end of 1999. During the mission, Discovery's four space-walking astronauts, Smith, Foale, Grunsfeld and Nicollier, spent 24 hours and 33 minutes upgrading and refurbishing Hubble, making it more capable than ever to renew its observations of the universe. Mission objectives included replacing gyroscopes and an old computer, installing another solid state recorder, and replacing damaged insulation in the telescope. Hubble was released from the end of Discovery's robot arm on Christmas Day. Main gear touchdown was at 7:00:47 p.m. EST. Nose gear touchdown occurred at 7:00:58 p.m. EST and wheel stop at 7:01:34 p.m. EST. This was the 96th flight in the Space Shuttle program and the 27th for the orbiter Discovery. The landing was the 20th consecutive Shuttle landing in Florida and the 13th night landing in Shuttle program history

  14. Developing computer-based training programs for basic mammalian histology: Didactic versus discovery-based design

    NASA Astrophysics Data System (ADS)

    Fabian, Henry Joel

    Educators have long tried to understand what stimulates students to learn. The Swiss psychologist and zoologist, Jean Claude Piaget, suggested that students are stimulated to learn when they attempt to resolve confusion. He reasoned that students try to explain the world with the knowledge they have acquired in life. When they find their own explanations to be inadequate to explain phenomena, students find themselves in a temporary state of confusion. This prompts students to seek more plausible explanations. At this point, students are primed for learning (Piaget 1964). The Piagetian approach described above is called learning by discovery. To promote discovery learning, a teacher must first allow the student to recognize his misconception and then provide a plausible explanation to replace that misconception (Chinn and Brewer 1993). One application of this method is found in the various learning cycles, which have been demonstrated to be effective means for teaching science (Renner and Lawson 1973, Lawson 1986, Marek and Methven 1991, and Glasson & Lalik 1993). In contrast to the learning cycle, tutorial computer programs are generally not designed to correct student misconceptions, but rather follow a passive, didactic method of teaching. In the didactic or expositional method, the student is told about a phenomenon, but is neither encouraged to explore it, nor explain it in his own terms (Schneider and Renner 1980).

  15. STS-103 perfect night-time landing for Space Shuttle Discovery

    NASA Technical Reports Server (NTRS)

    1999-01-01

    The orbiter Discovery looks like a blue ghost as it drops from the darkness onto lighted runway 33 at KSC's Shuttle Landing Facility. After traveling more than 3,267,000 miles on a successful eight-day mission to service the Hubble Space Telescope, the orbiter touches down at 7:00:47 p.m. EST. Aboard are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland and Jean-Frangois Clervoy of France, who spent the Christmas holiday in space in order to accomplish their mission before the end of 1999. During the mission, Discovery's four space-walking astronauts, Smith, Foale, Grunsfeld and Nicollier, spent 24 hours and 33 minutes upgrading and refurbishing Hubble, making it more capable than ever to renew its observations of the universe. Mission objectives included replacing gyroscopes and an old computer, installing another solid state recorder, and replacing damaged insulation in the telescope. Hubble was released from the end of Discovery's robot arm on Christmas Day. This was the 96th flight in the Space Shuttle program and the 27th for the orbiter Discovery. The landing was the 20th consecutive Shuttle landing in Florida and the 13th night landing in Shuttle program history.

  16. KSC-99pp1511

    NASA Image and Video Library

    1999-12-27

    KENNEDY SPACE CENTER, Fla. -- The orbiter Discovery looks like a blue ghost as it drops from the darkness onto lighted runway 33 at KSC's Shuttle Landing Facility. After traveling more than 3,267,000 miles on a successful eight-day mission to service the Hubble Space Telescope, the orbiter touches down at 7:00:47 p.m. EST. Aboard are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland and Jean-François Clervoy of France, who spent the Christmas holiday in space in order to accomplish their mission before the end of 1999. During the mission, Discovery's four space-walking astronauts, Smith, Foale, Grunsfeld and Nicollier, spent 24 hours and 33 minutes upgrading and refurbishing Hubble, making it more capable than ever to renew its observations of the universe. Mission objectives included replacing gyroscopes and an old computer, installing another solid state recorder, and replacing damaged insulation in the telescope. Hubble was released from the end of Discovery's robot arm on Christmas Day. This was the 96th flight in the Space Shuttle program and the 27th for the orbiter Discovery. The landing was the 20th consecutive Shuttle landing in Florida and the 13th night landing in Shuttle program history

  17. Final report on development and testing of the microwave oil-water monitor

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Swanson, C.

    1991-06-15

    The oil-water monitor is a device invented by Dr. Claude Swanson of Applied Physics Technology to respond to the petroleum-loss problem in crude oil transfers. It is a device which measures water content in crude oil and other petroleum products, in a flowing pipe such as a pipeline or tanker manifold. It is capable of accurately measuring the water contamination levels in crude oil shipments, in real time as the crude oil flows through the loading manifold into the tanker, or at the receiving point as the oil is off-loaded. The oil-water monitor has application in the verification of oilmore » volumes and concentration of contaminants at petroleum transfer points. The industry-estimated level of water loss at transfer points due to inadequate monitoring technology amounts to several billion dollars per year, so there is a definite perceived need within the petroleum community for this type of accurate water monitoring technology. News articles indicating the importance of this problem are shown. The microwave oil-water monitor measures the water content in the oil, whether in the form of small droplets or large globules. Therefore it can be applied to the crude oil as it flows through crude oil pipes into the ship, or at transfer points in a crude oil distribution system. 4 refs., 18 figs.« less

  18. Vision loss and hearing loss in painting and musical composition.

    PubMed

    Marmor, Michael F

    2014-07-01

    This article considers the impact of vision and hearing loss on great painters and musical composers. The visual work of Mary Cassatt, Georgia O'Keeffe, Edgar Degas, and Claude Monet all showed alterations as their vision failed. In contrast, Gabriel Fauré, Bedřich Smetana, and Ludwig von Beethoven wrote many of their best compositions while totally deaf, and Georg Friedrich Handel and Frederick Delius struggled to compose late in life when they lost their vision (although their hearing remained excellent). There are 2 major distinctions between the role of vision and hearing for these artistic disciplines. First, there is a surrogate means of "hearing" music, through the musical score, which allows composers to write and edit music while totally deaf. The greatest problem with deafness for a skilled composer is interference from internal noise (tinnitus). There is no surrogate for vision to allow a painter to work when the subject is a blur or the colors on the canvas cannot be distinguished. Second, although the appreciation of art is visual and that of music is auditory, the transcription of both art and musical composition is visual. Thus, visual loss does pose a problem for a composer accustomed to working with good sight, because it disrupts habitual methods of writing and editing music. Copyright © 2014 American Academy of Ophthalmology. Published by Elsevier Inc. All rights reserved.

  19. Monet's painting under the microscope.

    PubMed

    Dredge, Paula; Wuhrer, Richard; Phillips, Matthew R

    2003-04-01

    An oil painting by Claude Monet, Port-Goulphar, Belle-Ile 1887 (collection of the Art Gallery of New South Wales), was examined to determine both the identity of the pigments used by the artist in this painting and his technique of mixing colors and laying paint on the canvas. The extremely complex construction of the painting was revealed by optical microscopy, scanning electron microscopy (SEM), energy dispersive X-ray analysis (EDS), and X-ray mapping (XRM) analysis of cross sections of paint flakes excised from damaged regions of Port-Goulphar, Belle-Ile. Nine different pigments were found on the painting. Many of the identified colors were modern pigments that became available only late in the 19th century as a result of scientific advances in pigment chemistry. Although similar colors were available in a natural mineral form, they lacked the vivid color of their manufactured counterparts. The use of these new synthetic metallic oxide colors by Monet accounts for the brilliance of his paintings. In addition, a separation between successive paint layers was observed in some areas of paint chip cross sections, indicating that oil-based paint was applied to paint that had dried, and consequently, Port-Goulphar, Belle-Ile was painted over a long period of time. This observation is contrary to the general perception of Monet's technique of painting freely and quickly.

  20. STS-103 crew take part in CEIT

    NASA Technical Reports Server (NTRS)

    1999-01-01

    In the Payload Hazardous Servicing Facility, members of the STS-103 crew look at some of the equipment to be used during their mission. The seven-member crew are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland, and Jean-Frangois Clervoy of France. Nicollier and Clervoy are with the European Space Agency. Mission STS-103 is a 'call-up' due to the need to replace portions of the pointing system, the gyros, which have begun to fail on the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. The gyroscopes allow the telescope to point at stars, galaxies and planets. The STS-103 crew will not only replace gyroscopes, it will also replace a Fine Guidance Sensor and an older computer with a new enhanced model, an older data tape recorder with a solid state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. The scheduled launch date in October is under review.

  1. STS-103 crew take part in CEIT

    NASA Technical Reports Server (NTRS)

    1999-01-01

    In the Payload Hazardous Servicing Facility, some of the STS-103 crew look over lubrication devices to be used during their mission. The seven-member crew are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland, and Jean-Frangois Clervoy of France. Nicollier and Clervoy are with the European Space Agency. Mission STS-103 is a 'call-up' due to the need to replace portions of the pointing system, the gyros, which have begun to fail on the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. The gyroscopes allow the telescope to point at stars, galaxies and planets. The STS-103 crew will not only replace gyroscopes, it will also replace a Fine Guidance Sensor and an older computer with a new enhanced model, an older data tape recorder with a solid state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. The scheduled launch date in October is under review.

  2. KSC-99pp1089

    NASA Image and Video Library

    1999-09-02

    In the Payload Hazardous Servicing Facility, members of the STS-103 crew look at some of the equipment to be used during their mission. The seven-member crew are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland, and Jean-François Clervoy of France. Nicollier and Clervoy are with the European Space Agency. Mission STS-103 is a "call-up" due to the need to replace portions of the pointing system, the gyros, which have begun to fail on the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. The gyroscopes allow the telescope to point at stars, galaxies and planets. The STS-103 crew will not only replace gyroscopes, it will also replace a Fine Guidance Sensor and an older computer with a new enhanced model, an older data tape recorder with a solid state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. The scheduled launch date in October is under review

  3. KSC-99pp1087

    NASA Image and Video Library

    1999-09-02

    In the Payload Hazardous Servicing Facility, some of the STS-103 crew look over lubrication devices to be used during their mission. The seven-member crew are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland, and Jean-François Clervoy of France. Nicollier and Clervoy are with the European Space Agency. Mission STS-103 is a "call-up" due to the need to replace portions of the pointing system, the gyros, which have begun to fail on the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. The gyroscopes allow the telescope to point at stars, galaxies and planets. The STS-103 crew will not only replace gyroscopes, it will also replace a Fine Guidance Sensor and an older computer with a new enhanced model, an older data tape recorder with a solid state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. The scheduled launch date in October is under review

  4. KSC-99pp1086

    NASA Image and Video Library

    1999-09-02

    In the Payload Hazardous Servicing Facility, the STS-103 crew look over equipment to be used during their mission. The seven-member crew, taking part in a Crew Equipment Interface Test, are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland, and Jean-François Clervoy of France. Nicollier and Clervoy are with the European Space Agency. Mission STS-103 is a "call-up" due to the need to replace portions of the pointing system, the gyros, which have begun to fail on the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. The gyroscopes allow the telescope to point at stars, galaxies and planets. The STS-103 crew will not only replace gyroscopes, it will also replace a Fine Guidance Sensor and an older computer with a new enhanced model, an older data tape recorder with a solid state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. The scheduled launch date in October is under review

  5. Foreword

    NASA Astrophysics Data System (ADS)

    Aime, C.; Soummer, R.

    very short explanation of how the reports are ordered is given here. The Journées of 2003 started with the delocalized lectures (delocalized means here “not in Paris”!) of the Collège de France, of Antoine Labeyrie who wrote a report on Removal of coronagraphy residues with an adaptive hologram. Three invited seminars follow: Olivier Guyon (Pupil remapping techniques), Daniel Rouan (Ultra-nulling interferometers), and Kjetil Dohlen (Phase masks in astronomy). An illustration from Daniel Rouan's talk on the properties of Prouhet-Thué-Morse series was also selected for the cover figure of this edition. These papers are followed by the courses and communications given during the 4 days of the school, in a slightly different order of their presentation. The first two days were on atmospheric turbulence and adaptive optics for coronagraphy, and also coronagraphic space projects. Steve Ridgway gives a general introduction to the problem (Astronomy with high contrast imaging). This is followed by a presentation on Fourier and Statistical Optics: Shaped and Apodized apertures (Claude Aime), The effect of a coronagraph on the statistics of adaptive optics pinned speckles (Claude Aime and Rémi Soummer). A general introduction to the problem of atmospheric turbulence is made by Julien Borgnino. A presentation of the Concordia site with emphasis on its advantages for high contrast imaging is given by Eric Fossat. Several presentations relative to numerical simulations of Adaptive Optics and coronagraphy follow: Marcel Carbillet (AO for very high contrast imaging), Lyu Abe and Anthony Boccaletti share two presentations on Numerical simulations for coronagraphy. These presentations are followed by reports on experiments: Sandrine Thomas (SAM-the SOAR adaptive module), Pierre Baudoz (Cryogenic IR test of the 4QPM coronagraph), Anthony Boccaletti (Coronagraphy with JWST in the thermal IR). Pierre Bourget (Hg-Mask Coronagraph) ends this part with a coronagraph using a mercury

  6. "Requestioning" AIDS: An Ethical Reflection From 1993 to Today. Reflections on Claude Vandevyer's "Homosexuals and AIDS: A New Approach to the Illness" from Journal of Homosexuality 25(3).

    PubMed

    Lau, Travis

    2016-01-01

    This article serves as one of the supplementary pieces of this special issue on "Mapping Queer Bioethics," in which we take a solipsistic turn to "map" the Journal of Homosexuality itself. Here, the author examines the first feature-length article to address the relationship between HIV status and homosexuality. Lingering on both the temporal gap between the dawn of AIDS in American discourse and its inclusion in this journal, the author asks us to consider (in hindsight) such a delay bearing in mind queer theoretical projects of the present such as gay shame, stigma, and queer biopolitics.

  7. Determinism and probability in the development of the cell theory.

    PubMed

    Duchesneau, François

    2012-09-01

    A return to Claude Bernard's original use of the concept of 'determinism' displays the fact that natural laws were presumed to rule over all natural processes. In a more restricted sense, the term boiled down to a mere presupposition of constant determinant causes for those processes, leaving aside any particular ontological principle, even stochastic. The history of the cell theory until around 1900 was dominated by a twofold conception of determinant causes. Along a reductionist trend, cells' structures and processes were supposed to be accounted for through their analysis into detailed partial mechanisms. But a more holistic approach tended to subsume those analytic means and the mechanism involved under a program of global functional determinations. When mitotic and meiotic sequences in nuclear replication were being unveiled and that neo-Mendelian genetics was being grafted onto cytology and embryology, a conception of strict determinism at the nuclear level, principally represented by Wilhelm Roux and August Weismann, would seem to rule unilaterally over the mosaic interpretation of the cleavage of blastomeres. But, as shown by E.B. Wilson, in developmental processes there occur contingent outcomes of cell division which observations and experiments reveal. This induces the need to admit 'epigenetic' determinants and relativize the presumed 'preformation' of thedevelopmental phases by making room for an emergent order which the accidental circumstances of gene replication would trigger on. Copyright © 2012 Elsevier Ltd. All rights reserved.

  8. STS-103 crew take part in CEIT

    NASA Technical Reports Server (NTRS)

    1999-01-01

    In the Payload Hazardous Servicing Facility, STS-103 Mission Specialist Steven L. Smith (right) and other members of the crew look over new Multi-Layer Insulation (MLI) intended for the Hubble Space Telescope. The seven-member crew, taking part in a Crew Equipment Interface Test, are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, and Mission Specialists Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland, and Jean-Frangois Clervoy of France. Nicollier and Clervoy are with the European Space Agency. Mission STS-103 is a 'call-up' due to the need to replace portions of the pointing system, the gyros, which have begun to fail on the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. The gyroscopes allow the telescope to point at stars, galaxies and planets. The STS-103 crew will not only replace gyroscopes, it will also replace a Fine Guidance Sensor and an older computer with a new enhanced model, an older data tape recorder with a solid state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with the MLI. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. The scheduled launch date in October is under review.

  9. Space polypropulsion

    NASA Astrophysics Data System (ADS)

    Kellett, B. J.; Griffin, D. K.; Bingham, R.; Campbell, R. N.; Forbes, A.; Michaelis, M. M.

    2008-05-01

    Hybrid space propulsion has been a feature of most space missions. Only the very early rocket propulsion experiments like the V2, employed a single form of propulsion. By the late fifties multi-staging was routine and the Space Shuttle employs three different kinds of fuel and rocket engines. During the development of chemical rockets, other forms of propulsion were being slowly tested, both theoretically and, relatively slowly, in practice. Rail and gas guns, ion engines, "slingshot" gravity assist, nuclear and solar power, tethers, solar sails have all seen some real applications. Yet the earliest type of non-chemical space propulsion to be thought of has never been attempted in space: laser and photon propulsion. The ideas of Eugen Saenger, Georgii Marx, Arthur Kantrowitz, Leik Myrabo, Claude Phipps and Robert Forward remain Earth-bound. In this paper we summarize the various forms of nonchemical propulsion and their results. We point out that missions beyond Saturn would benefit from a change of attitude to laser-propulsion as well as consideration of hybrid "polypropulsion" - which is to say using all the rocket "tools" available rather than possibly not the most appropriate. We conclude with three practical examples, two for the next decades and one for the next century; disposal of nuclear waste in space; a grand tour of the Jovian and Saturnian moons - with Huygens or Lunoxod type, landers; and eventually mankind's greatest space dream: robotic exploration of neighbouring planetary systems.

  10. Rotating disk atomization of Gd and Gd-Y for hydrogen liquefaction via magnetocaloric cooling

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Slinger, Tyler

    2016-12-17

    In order to enable liquid hydrogen fuel cell technologies for vehicles the cost of hydrogen liquefaction should be lowered. The current method of hydrogen liquefaction is the Claude cycle that has a figure of merit (FOM) of 0.3-0.35. New magnetocaloric hydrogen liquefaction devices have been proposed with a FOM>0.5, which is a significant improvement. A significant hurdle to realizing these devices is the synthesis of spherical rare earth based alloy powders of 200μm in diameter. In this study a centrifugal atomization method that used a rotating disk with a rotating oil quench bath was developed to make gadolinium and gadolinium-yttriummore » spheres. The composition of the spherical powders included pure Gd and Gd 0.91Y 0.09. The effect of atomization parameters, such as superheat, melt properties, disk shape, disk speed, and melt system materials and design, were investigated on the size distribution and morphology of the resulting spheres. The carbon, nitrogen, and oxygen impurity levels also were analyzed and compared with the magnetic performance of the alloys. The magnetic properties of the charge material as well as the resulting powders were measured using a vibrating sample magnetometer. The saturation magnetization and Curie temperature were the target properties for the resulting spheres. These values were compared with measurements taken on the charge material in order to investigate the effect of atomization processing on the alloys.« less

  11. STS-103 crew take part in CEIT

    NASA Technical Reports Server (NTRS)

    1999-01-01

    During a Crew Equipment Interface Test, STS-103 Commander Curtis L. Brown Jr. (left) and Pilot Scott J. Kelly look at a replacement computer for the Hubble Space Telescope. The payload hardware is in the Payload Hazardous Servicing Facility. Other members of the crew are Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland, and Jean-Frangois Clervoy of France. Nicollier and Clervoy are with the European Space Agency. Mission STS-103 is a 'call-up' due to the need to replace portions of the pointing system, the gyros, which have begun to fail on the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. The gyroscopes allow the telescope to point at stars, galaxies and planets. The STS-103 crew will not only replace gyroscopes, it will also replace a Fine Guidance Sensor and an older computer with the new enhanced model, an older data tape recorder with a solid state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. The scheduled launch date in October is under review.

  12. [On the evolution of scientific thought].

    PubMed

    de Micheli, Alfredo; Iturralde Torres, Pedro

    2015-01-01

    The Nominalists of the XIV century, precursors of modern science, thought that science's object was not the general, vague and indeterminate but the particular, which is real and can be known directly. About the middle of the XVII Century the bases of the modern science became established thanks to a revolution fomented essentially by Galileo, Bacon and Descartes. During the XVIII Century, parallel to the development of the great current of English Empiricism, a movement of scientific renewal also arose in continental Europe following the discipline of the Dutch Physicians and of Boerhaave. In the XIX Century, Claude Bernard dominated the scientific medicine but his rigorous determinism impeded him from taking into account the immense and unforeseeable field of the random. Nowadays, we approach natural science and medicine, from particular groups of facts; that is, from the responses of Nature to specific questions, but not from the general laws. Furthermore, in recent epistemology, the concept that experimental data are not pure facts, but rather, facts interpreted within a hermeneutical context has been established. Finally a general tendency to retrieve philosophical questions concerning the understanding of essence and existence can frequently be seen in scientific inquiry. In the light of the evolution of medical thought, it is possible to establish the position of scientific medicine within the movement of ideas dominating in our time. Copyright © 2014 Instituto Nacional de Cardiología Ignacio Chávez. Published by Masson Doyma México S.A. All rights reserved.

  13. STS-103 crew look over payload inside Discovery

    NASA Technical Reports Server (NTRS)

    1999-01-01

    At Launch Pad 39B, STS-103 Mission Specialist C. Michael Foale (Ph.D.) looks over the Hubble servicing cargo in the payload bay of Space Shuttle Discovery. The activity is part of the Terminal Countdown Demonstration Test (TCDT), which also provides the crew with emergency egress training and a simulated countdown exercise. Other crew members taking part in the TCDT are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, and Mission Specialists Steven L. Smith, John M. Grunsfeld (Ph.D.), Jean- Fran'''ois Clervoy of France, and Claude Nicollier of Switzerland. Clervoy and Nicollier are with the European Space Agency. STS-103 is a 'call-up' mission due to the need to replace and repair portions of the Hubble Space Telescope, including the gyroscopes that allow the telescope to point at stars, galaxies and planets. The STS-103 crew will be replacing a Fine Guidance Sensor, an older computer with a new enhanced model, an older data tape recorder with a solid-state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The mission is targeted for launch Dec. 6 at 2:37 a.m. EST.

  14. STS-103 crew wait inside Discovery for simulated countdown exercise

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Seated in the orbiter Discovery for a simulated countdown exercise is STS-103 Pilot Scott J. Kelly. The simulation is part of Terminal Countdown Demonstration Test (TCDT) activities. The TCDT also provides the crew with emergency egress training and opportunities to inspect their mission payload in the orbiter's payload bay. Other crew members taking part in the TCDT are Commander Curtis L. Brown Jr., and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Jean- Fran'''ois Clervoy of France, and Claude Nicollier of Switzerland. Clervoy and Nicollier are with the European Space Agency. STS-103 is a 'call-up' mission due to the need to replace and repair portions of the Hubble Space Telescope, including the gyroscopes that allow the telescope to point at stars, galaxies and planets. The STS-103 crew will be replacing a Fine Guidance Sensor, an older computer with a new enhanced model, an older data tape recorder with a solid-state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The mission is targeted for launch Dec. 6 at 2:37 a.m. EST.

  15. STS-103 crew wait inside Discovery for simulated countdown exercise

    NASA Technical Reports Server (NTRS)

    1999-01-01

    STS-103 Mission Specialist John M. Grunsfeld (Ph.D.) sits inside orbiter Discovery waiting for the start of a simulated countdown exercise. The simulation is part of Terminal Countdown Demonstration Test (TCDT) activities. The TCDT also provides the crew with emergency egress training and opportunities to inspect their mission payload in the orbiter's payload bay. Other crew members taking part in the TCDT are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), Jean-Fran'''ois Clervoy of France, and Claude Nicollier of Switzerland. Clervoy and Nicollier are with the European Space Agency. STS-103 is a 'call-up' mission due to the need to replace and repair portions of the Hubble Space Telescope, including the gyroscopes that allow the telescope to point at stars, galaxies and planets. The STS-103 crew will be replacing a Fine Guidance Sensor, an older computer with a new enhanced model, an older data tape recorder with a solid-state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The mission is targeted for launch Dec. 6 at 2:37 a.m. EST.

  16. STS-103 crew wait inside Discovery for simulated countdown exercise

    NASA Technical Reports Server (NTRS)

    1999-01-01

    STS-103 Mission Commander Curtis L. Brown Jr. sits inside orbiter Discovery waiting for the start of a simulated countdown exercise. The simulation is part of Terminal Countdown Demonstration Test (TCDT) activities. The TCDT also provides the crew with emergency egress training and opportunities to inspect their mission payload in the orbiter's payload bay. Other crew members taking part in the TCDT are Pilot Scott J. Kelly, and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Jean-Fran'''ois Clervoy of France, and Claude Nicollier of Switzerland. Clervoy and Nicollier are with the European Space Agency. STS-103 is a 'call-up' mission due to the need to replace and repair portions of the Hubble Space Telescope, including the gyroscopes that allow the telescope to point at stars, galaxies and planets. The STS-103 crew will be replacing a Fine Guidance Sensor, an older computer with a new enhanced model, an older data tape recorder with a solid-state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The mission is targeted for launch Dec. 6 at 2:37 a.m. EST.

  17. [Protoplasm, coagulation and colloids : Forgotten chapter in the research history of anesthesia between Zeitgeist and paradigm].

    PubMed

    Perouansky, M

    2015-05-01

    The historically most important mechanistic theories attributed the fundamental cause of anesthesia to interactions betweeen anesthetics and proteins as early as the 1870s. According to the underlying thought, the resulting changes in the consistency of cellular protoplasm were the cause of the anesthetized state of the whole organism.These protoplasm coagulation theories, as they were collectively referred to, brought the contemporary enthusiasm for protoplasm, the rapid advances in colloid chemistry and the unified theory of narcosis proclamed by Claude Bernard under a unified mechanistic theory that reflected the Zeitgeist of the epoch.This research effort, on the intersection of the developing disciplines of cellular biology and colloid chemistry, lasted for almost a century. It involved scientists of worldwide reputation and resulted in a number of elegant theories. Contrary to widespread opinion, proteins and not lipids were recognized and investigated first as the critical molecular target of anesthetics more than a century prior to their much publicized rediscovery in 1984.The protoplasm coagulation theories of anesthesia were pursued after the First World War across ideological trenches by scientists in Europe, the Soviet Union and the United States. They united research in anesthesia with research of fundamental cell biology.In contrast to the much less fruitful lipid theories, protoplasm coagulation theories are largely forgotten without leaving a trace in contemporary discussions of the history of anesthesia. For many tyears, however, they constituted an essential part of fundamental anesthetic research and must therefore be mentioned in any historical review.

  18. KSC-99pp1477

    NASA Image and Video Library

    1999-12-19

    KENNEDY SPACE CENTER, FLA. -- As if spawned by the clouds of smoke and steam below, the Space Shuttle Discovery shoots into the night sky on mission STS-103. The brilliant light creates a reflection of the launch in the water nearby. Liftoff occurred at 7:50 p.m. EST from Launch Pad 39B. On board are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland and Jean-François Clervoy of France. Nicollier and Clervoy are with the European Space Agency. STS-103 is a Hubble Servicing Mission, with three planned space walks designed to install new equipment and replace old. The primary objective is to replace the gyroscopes that make up the three Rate Sensor Units. Extravehicular activities include installing a new computer, changing out one of the Fine Guidance Sensors, replacing a tape recorder with a new solid state recorder, and installing a voltage/temperature improvement kit, and begin repairing the insulation on the telescope's outer surface. After the 7-day, 21-hour mission, Discovery is expected to land at KSC Monday, Dec. 27, at about 5:24 p.m. EST. This is the 27th flight of Discovery and the 96th mission in the Space Shuttle Program. It is the third launch at Kennedy Space Center in 1999

  19. KSC-99pp1331

    NASA Image and Video Library

    1999-11-16

    In the bunker at Launch Pad 39B, STS-103 Mission Specialist Jean-François Clervoy of France, who is with the European Space Agency (ESA), tries on an oxygen mask during Terminal Countdown Demonstration Test (TCDT) activities. The TCDT provides the crew with emergency egress training, opportunities to inspect their mission payloads in the orbiter's payload bay, and simulated countdown exercises. Other crew members taking part are Commander Curtis L. Brown Jr. and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), plus Claude Nicollier of Switzerland, who is also with ESA. STS-103 is a "call-up" mission due to the need to replace and repair portions of the Hubble Space Telescope, including the gyroscopes that allow the telescope to point at stars, galaxies and planets. The STS-103 crew will be replacing a Fine Guidance Sensor, an older computer with a new enhanced model, an older data tape recorder with a solid-state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The mission is targeted for launch Dec. 6 at 2:37 a.m. EST

  20. The latest developments and outlook for hydrogen liquefaction technology

    NASA Astrophysics Data System (ADS)

    Ohlig, K.; Decker, L.

    2014-01-01

    Liquefied hydrogen is presently mainly used for space applications and the semiconductor industry. While clean energy applications, for e.g. the automotive sector, currently contribute to this demand with a small share only, their demand may see a significant boost in the next years with the need for large scale liquefaction plants exceeding the current plant sizes by far. Hydrogen liquefaction for small scale plants with a maximum capacity of 3 tons per day (tpd) is accomplished with a Brayton refrigeration cycle using helium as refrigerant. This technology is characterized by low investment costs but lower process efficiency and hence higher operating costs. For larger plants, a hydrogen Claude cycle is used, characterized by higher investment but lower operating costs. However, liquefaction plants meeting the potentially high demand in the clean energy sector will need further optimization with regard to energy efficiency and hence operating costs. The present paper gives an overview of the currently applied technologies, including their thermodynamic and technical background. Areas of improvement are identified to derive process concepts for future large scale hydrogen liquefaction plants meeting the needs of clean energy applications with optimized energy efficiency and hence minimized operating costs. Compared to studies in this field, this paper focuses on application of new technology and innovative concepts which are either readily available or will require short qualification procedures. They will hence allow implementation in plants in the close future.

  1. Overview of Air Liquide refrigeration systems between 1.8 K and 200 K

    NASA Astrophysics Data System (ADS)

    Gondrand, C.; Durand, F.; Delcayre, F.; Crispel, S.; Baguer, G. M. Gistau

    2014-01-01

    Cryogenic refrigeration systems are necessary for numerous applications. Gas purification and distillation require temperatures between 15 K and 200 K depending on the application, space simulation chambers down to 15 K, superconductivity between 1.8 K and up to 75 K (magnets, cavities or HTS devices like cables, FCL, SMES, etc), Cold Neutron Sources between 15 and 20 K, etc. Air Liquide Advanced Technologies is designing and manufacturing refrigerators since 60 years to satisfy those needs. The step by step developments achieved have led to machines with higher efficiency and reliability. In 1965, reciprocating compressors and Joule Thomson expansion valves were used. In 1969, centripetal expanders began to be used. In 1980, oil lubricated screw compressors took the place of reciprocating compressors and a standard range of Claude cycle refrigerators was developed: the HELIAL series. 1980 was also the time for cryogenic centrifugal compressor development. In 2011, driven by the need for lower operational cost (high efficiency and low maintenance), cycle oil free centrifugal compressors on magnetic bearings were introduced instead of screw compressors. The power extracted by centripetal expanders was recovered. Based on this technology, a range of Turbo-Brayton refrigerators has been designed for temperatures between 40 K and 150 K. On-going development will enable widening the range of Turbo-Brayton refrigerators to cryogenic temperatures down to 15 K.. Cryogenic centrifugal circulators have been developed in order to answer to an increasing demand of 4 K refrigerators able to distribute cold power.

  2. STS-103 crew take part in CEIT in PHSF

    NASA Technical Reports Server (NTRS)

    1999-01-01

    In the Payload Hazardous Servicing Facility, four STS-103 crew members check the Flight Support System avionics to be used for repair and upgrade of the Hubble Space Telescope. The crew are at KSC to take part in a Crew Equipment Interface Test. The seven-member crew comprises Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D), Claude Nicollier of Switzerland, and Jean-Frangois Clervoy of France. Nicollier and Clervoy are with the European Space Agency. Mission STS-103 is a 'call-up' due to the need to replace portions of the pointing system, the gyros, which have begun to fail on the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. The gyroscopes allow the telescope to point at stars, galaxies and planets. The STS-103 crew will not only replace gyroscopes, it will also replace a Fine Guidance Sensor and an older computer with a new enhanced model, an older data tape recorder with a solid-state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. The scheduled launch date in October is under review.

  3. STS-103 crew take part in CEIT in PHSF

    NASA Technical Reports Server (NTRS)

    1999-01-01

    During a Crew Equipment Interface Test (CEIT), members of the STS-103 crew check out a portable foot restraint on the Flight Support System that will be used on the mission, repairing the Hubble Space Telescope. The seven-member crew comprises Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D), Claude Nicollier of Switzerland, and Jean-Frangois Clervoy of France. Nicollier and Clervoy are with the European Space Agency. Mission STS-103 is a 'call-up' due to the need to replace portions of the pointing system, the gyros, which have begun to fail on the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. The gyroscopes allow the telescope to point at stars, galaxies and planets. The STS-103 crew will not only replace gyroscopes, it will also replace a Fine Guidance Sensor and an older computer with a new enhanced model, an older data tape recorder with a solid-state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. The scheduled launch date in October is under review.

  4. STS-103 MS Clervoy and Nicollier and Commander Brown look over Discovery after landing

    NASA Technical Reports Server (NTRS)

    1999-01-01

    After landing at the Shuttle Landing Facility, STS-103 Mission Specialists Jean-Francois Clervoy of France and Claude Nicollier of Switzerland, who are with the European Space Agency, listen to a comment by Commander Curtis L. Brown Jr. while looking over the orbiter Discovery. Other members of the crew are Pilot Scott J. Kelly and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), and John M. Grunsfeld (Ph.D.). The crew of seven completed a successful eight-day mission to service the Hubble Space Telescope, spending the Christmas holiday in space in order to accomplish their mission before the end of 1999. During the mission, Discovery's four space-walking astronauts, Smith, Foale, Grunsfeld and Nicollier, spent 24 hours and 33 minutes upgrading and refurbishing Hubble, making it more capable than ever to renew its observations of the universe. Mission objectives included replacing gyroscopes and an old computer, installing another solid state recorder, and replacing damaged insulation in the telescope. Hubble was released from the end of Discovery's robot arm on Christmas Day. Main gear touchdown was at 7:00:47 p.m. EST. Nose gear touchdown occurred at 7:00:58 EST and wheel stop at 7:01:34 EST. This was the 96th flight in the Space Shuttle program and the 27th for the orbiter Discovery. The landing was the 20th consecutive Shuttle landing in Florida and the 13th night landing in Shuttle program history.

  5. STS-103 Pilot Scott Kelly and MS John Grunsfeld try on oxygen masks

    NASA Technical Reports Server (NTRS)

    1999-01-01

    In the bunker at Launch Pad 39B, STS-103 Pilot Scott J. Kelly (left) and Mission Specialist John M. Grunsfeld (Ph.D.) (right) try on oxygen masks during Terminal Countdown Demonstration Test (TCDT) activities. The TCDT provides the crew with emergency egress training, opportunities to inspect their mission payloads in the orbiter's payload bay, and simulated countdown exercises. Other crew members taking part are Commander Curtis L. Brown Jr. and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), and Jean-Frangois Clervoy of France and Claude Nicollier of Switzerland, who are with the European Space Agency. STS-103 is a 'call-up' mission due to the need to replace and repair portions of the Hubble Space Telescope, including the gyroscopes that allow the telescope to point at stars, galaxies and planets. The STS-103 crew will be replacing a Fine Guidance Sensor, an older computer with a new enhanced model, an older data tape recorder with a solid-state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The mission is targeted for launch Dec. 6 at 2:37 a.m. EST.

  6. STS-103 MS Clervoy tries on oxygen mask

    NASA Technical Reports Server (NTRS)

    1999-01-01

    In the bunker at Launch Pad 39B, STS-103 Mission Specialist Jean-Frangois Clervoy of France, who is with the European Space Agency (ESA), tries on an oxygen mask during Terminal Countdown Demonstration Test (TCDT) activities. The TCDT provides the crew with emergency egress training, opportunities to inspect their mission payloads in the orbiter's payload bay, and simulated countdown exercises. Other crew members taking part are Commander Curtis L. Brown Jr. and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), plus Claude Nicollier of Switzerland, who is also with ESA. STS-103 is a 'call-up' mission due to the need to replace and repair portions of the Hubble Space Telescope, including the gyroscopes that allow the telescope to point at stars, galaxies and planets. The STS-103 crew will be replacing a Fine Guidance Sensor, an older computer with a new enhanced model, an older data tape recorder with a solid-state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The mission is targeted for launch Dec. 6 at 2:37 a.m. EST.

  7. KSC-99pp1510

    NASA Image and Video Library

    1999-12-27

    After landing at the Shuttle Landing Facility, the STS-103 crew poses in front of the orbiter Discovery. Standing left to right are Commander Curtis L. Brown Jr., Mission Specialist Claude Nicollier of Switzerland, Pilot Scott J. Kelly, and Mission Specialists Jean-Francois Clervoy of France, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.) and Steven L. Smith. The crew of seven completed a successful eight-day mission to service the Hubble Space Telescope, spending the Christmas holiday in space in order to accomplish their mission before the end of 1999. During the mission, Discovery's four space-walking astronauts, Smith, Foale, Grunsfeld and Nicollier, spent 24 hours and 33 minutes upgrading and refurbishing Hubble, making it more capable than ever to renew its observations of the universe. Mission objectives included replacing gyroscopes and an old computer, installing another solid state recorder, and replacing damaged insulation in the telescope. Hubble was released from the end of Discovery's robot arm on Christmas Day. Main gear touchdown was at 7:00:47 p.m. EST. Nose gear touchdown occurred at 7:00:58 p.m. EST and wheel stop at 7:01:34 p.m. EST. This was the 96th flight in the Space Shuttle program and the 27th for the orbiter Discovery. The landing was the 20th consecutive Shuttle landing in Florida and the 13th night landing in Shuttle program history

  8. KSC-99pp1505

    NASA Image and Video Library

    1999-12-27

    After landing at the Shuttle Landing Facility, STS-103 Mission Specialist Jean-François Clervoy of France (left), with the European Space Agency (ESA), and Commander Curtis L. Brown Jr. (right) look over the orbiter Discovery. They and other crew members Pilot Scott J. Kelly and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.) and Claude Nicollier of Switzerland (also with ESA), completed a successful eight-day mission to service the Hubble Space Telescope, spending the Christmas holiday in space in order to accomplish their mission before the end of 1999. During the mission, Discovery's four space-walking astronauts, Smith, Foale, Grunsfeld and Nicollier, spent 24 hours and 33 minutes upgrading and refurbishing Hubble, making it more capable than ever to renew its observations of the universe. Mission objectives included replacing gyroscopes and an old computer, installing another solid state recorder, and replacing damaged insulation in the telescope. Hubble was released from the end of Discovery's robot arm on Christmas Day. Main gear touchdown was at 7:00:47 p.m. EST. Nose gear touchdown occurred at 7:00:58 p.m. EST and wheel stop at 7:01:34 p.m. EST. This was the 96th flight in the Space Shuttle program and the 27th for the orbiter Discovery. The landing was the 20th consecutive Shuttle landing in Florida and the 13th night landing in Shuttle program history

  9. KSC-99pp1507

    NASA Image and Video Library

    1999-12-27

    After landing at the Shuttle Landing Facility, STS-103 Mission Specialists Jean-Francois Clervoy of France and Claude Nicollier of Switzerland, who are with the European Space Agency, listen to a comment by Commander Curtis L. Brown Jr. while looking over the orbiter Discovery. Other members of the crew are Pilot Scott J. Kelly and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), and John M. Grunsfeld (Ph.D.). The crew of seven completed a successful eight-day mission to service the Hubble Space Telescope, spending the Christmas holiday in space in order to accomplish their mission before the end of 1999. During the mission, Discovery's four space-walking astronauts, Smith, Foale, Grunsfeld and Nicollier, spent 24 hours and 33 minutes upgrading and refurbishing Hubble, making it more capable than ever to renew its observations of the universe. Mission objectives included replacing gyroscopes and an old computer, installing another solid state recorder, and replacing damaged insulation in the telescope. Hubble was released from the end of Discovery's robot arm on Christmas Day. Main gear touchdown was at 7:00:47 p.m. EST. Nose gear touchdown occurred at 7:00:58 p.m. EST and wheel stop at 7:01:34 p.m. EST. This was the 96th flight in the Space Shuttle program and the 27th for the orbiter Discovery. The landing was the 20th consecutive Shuttle landing in Florida and the 13th night landing in Shuttle program history

  10. KSC-99pp1504

    NASA Image and Video Library

    1999-12-27

    KENNEDY SPACE CENTER, Fla. -- The Space Shuttle Discovery drops out of the darkness onto runway 33 at the Shuttle Landing Facility after traveling more than 3,267,000 miles on a successful eight-day mission to service the Hubble Space Telescope. Astronauts Curtis L. Brown Jr., Commander; Scott J. Kelly, Pilot; and Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland and Jean-François Clervoy of France, all Mission Specialists, spent the Christmas holiday in space in order to accomplish their mission before the end of 1999. During the mission, Discovery's four space-walking astronauts, Smith, Foale, Grunsfeld and Nicollier, spent 24 hours and 33 minutes upgrading and refurbishing Hubble, making it more capable than ever to renew its observations of the universe. Mission objectives included replacing gyroscopes and an old computer, installing another solid state recorder, and replacing damaged insulation in the telescope. Hubble was released from the end of Discovery's robot arm on Christmas Day. Main gear touchdown was at 7:00:47 p.m. EST. Nose gear touchdown occurred at 7:00:58 p.m. EST and wheel stop at 7:01:34 p.m. EST. This was the 96th flight in the Space Shuttle program and the 27th for the orbiter Discovery. The landing was the 20th consecutive Shuttle landing in Florida and the 13th night landing in Shuttle program history

  11. Carbon from Crust to Core: A history of deep carbon science

    NASA Astrophysics Data System (ADS)

    Mitton, Simon

    2017-04-01

    As an academic historian of science, I am writing a history of the discovery of the interior workings of our dynamic planet. I am preparing a book, titled Carbon from Crust to Core: A Chronicle of Deep Carbon Science, in which I will present the first history of deep carbon science. I will identify and document key discoveries, the impact of new knowledge, and the roles of deep carbon scientists and their institutions from the 1400s to the present. This innovative book will set down the engaging human story of many remarkable scientists from whom we have learned about Earth's interior, and particularly the fascinating story of carbon in Earth. I will describe a great journey of discovery that has led to a better understanding of the physical, chemical, and biological behaviour of carbon in the vast majority of Earth's interior. My poster has a list of remarkable Deep Carbon Explorers, from Georgius Agricola (1494-1555) to Claude ZoBell (1904-1989). Come along to my poster and add to my compilation: choose pioneers from history, or nominate your colleagues, or even add a selfie! As a biographer, I am keen to add researchers who may have been overlooked in the standard histories of geology and geophysics. And I am always on the lookout for standout stories and personal recollections. I am equipped to do oral history interviews. What's your story? Cambridge University Press will publish the book in 2019.

  12. STS-103 crew looks over Discovery after a night-time landing at the SLF

    NASA Technical Reports Server (NTRS)

    1999-01-01

    After landing at the Shuttle Landing Facility, the STS-103 crew looks over the orbiter Discovery. In the foreground, from left, are Mission Specialist Jean-Francois Clervoy of France, Pilot Scott J. Kelly, Commander Curtis L. Brown Jr. and Mission Specialist C. Michael Foale (Ph.D.); behind them, from left, are Mission Specialists Steven L. Smith and Claude Nicollier of Switzerland. The remaining crew member (not shown) is Mission Specialist John M. Grunsfeld (Ph.D.). The crew of seven completed a successful eight-day mission to service the Hubble Space Telescope, spending the Christmas holiday in space in order to accomplish their mission before the end of 1999. During the mission, Discovery's four space-walking astronauts, Smith, Foale, Grunsfeld and Nicollier, spent 24 hours and 33 minutes upgrading and refurbishing Hubble, making it more capable than ever to renew its observations of the universe. Mission objectives included replacing gyroscopes and an old computer, installing another solid state recorder, and replacing damaged insulation in the telescope. Hubble was released from the end of Discovery's robot arm on Christmas Day. Main gear touchdown was at 7:00:47 p.m. EST. Nose gear touchdown occurred at 7:00:58 EST and wheel stop at 7:01:34 EST. This was the 96th flight in the Space Shuttle program and the 27th for the orbiter Discovery. The landing was the 20th consecutive Shuttle landing in Florida and the 13th night landing in Shuttle program history.

  13. STS-103 crew take part in CEIT

    NASA Technical Reports Server (NTRS)

    1999-01-01

    In the Payload Hazardous Servicing Facility, a member of the STS-103 crew checks out rib clamp to be used on the Shield Shell Replacement Fabric (SSRF) task on repair of the Hubble Space Telescope. The seven-member crew, taking part in a Crew Equipment Interface Test, are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland, and Jean-Frangois Clervoy of France. Nicollier and Clervoy are with the European Space Agency. Mission STS-103 is a 'call-up' due to the need to replace portions of the pointing system, the gyros, which have begun to fail on the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. The gyroscopes allow the telescope to point at stars, galaxies and planets. The STS-103 crew will not only replace gyroscopes, it will also replace a Fine Guidance Sensor and an older computer with a new enhanced model, an older data tape recorder with a solid state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. The scheduled launch date in October is under review.

  14. Does Stereotype Threat Affect Post-Course Scores on the Astronomy Diagnostic Test?

    NASA Astrophysics Data System (ADS)

    Deming, G. L.; Hufnagel, B.; Landato, J. M.; Hodari, A. K.

    2003-12-01

    During the 1990s, Claude Steele and others demonstrated that women mathematics students under-performed while men over-performed on selected GRE questions when told that the exam could differentiate by gender. Stereotype threat is triggered for these women when they fear someone else may negatively stereotype them, and therefore, their performance is affected. In a limited study involving 229 students, we investigated the effect of stereotype threat on performance on the Astronomy Diagnostic Test (ADT). The ADT was administered as a pre-test in four introductory astronomy classes intended for non-science majors. The same professors taught pairs of classes at the University of Maryland, a large research institution, and W. R. Harper College, a small liberal arts school. The classes were treated the same until the final day before the post-course ADT was given. One "threatened" class at each campus was told that gender mattered so they should be sure to include it on the ADT. The "control" classes were told that gender does not matter. The results show no stereotype threat effect on the women in these introductory classes. The university men did slightly over-perform at low statistical significance. As Steele suggested, students must identify with a subject in order to strongly invoke a stereotype threat. This research was supported in part by the National Science Foundation through grants REC-0089239 to GLD, DGE-97014489 to BH, and DGE-9714452 for AKH.

  15. The latest developments and outlook for hydrogen liquefaction technology

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ohlig, K.; Decker, L.

    2014-01-29

    Liquefied hydrogen is presently mainly used for space applications and the semiconductor industry. While clean energy applications, for e.g. the automotive sector, currently contribute to this demand with a small share only, their demand may see a significant boost in the next years with the need for large scale liquefaction plants exceeding the current plant sizes by far. Hydrogen liquefaction for small scale plants with a maximum capacity of 3 tons per day (tpd) is accomplished with a Brayton refrigeration cycle using helium as refrigerant. This technology is characterized by low investment costs but lower process efficiency and hence highermore » operating costs. For larger plants, a hydrogen Claude cycle is used, characterized by higher investment but lower operating costs. However, liquefaction plants meeting the potentially high demand in the clean energy sector will need further optimization with regard to energy efficiency and hence operating costs. The present paper gives an overview of the currently applied technologies, including their thermodynamic and technical background. Areas of improvement are identified to derive process concepts for future large scale hydrogen liquefaction plants meeting the needs of clean energy applications with optimized energy efficiency and hence minimized operating costs. Compared to studies in this field, this paper focuses on application of new technology and innovative concepts which are either readily available or will require short qualification procedures. They will hence allow implementation in plants in the close future.« less

  16. KSC-99pp1099

    NASA Image and Video Library

    1999-09-03

    During a Crew Equipment Interface Test (CEIT), members of the STS-103 crew check out tools to be used on planned Extravehicular Activities (EVAs) on the mission for repair of the Hubble Space Telescope. In uniform, from left, are Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), Claude Nicollier of Switzerland, and John M. Grunsfeld (Ph.D.). Other crew members at KSC for the CEIT are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, and Jean-François Clervoy of France. Nicollier and Clervoy are with the European Space Agency. Mission STS-103 is a "call-up" due to the need to replace portions of the pointing system, the gyros, which have begun to fail on the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. The gyroscopes allow the telescope to point at stars, galaxies and planets. The STS-103 crew will not only replace gyroscopes, it will also replace a Fine Guidance Sensor and an older computer with a new enhanced model, an older data tape recorder with a solid-state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. The scheduled launch date in October is under review

  17. KSC-99pp1092

    NASA Image and Video Library

    1999-09-02

    During a Crew Equipment Interface Test, STS-103 Commander Curtis L. Brown Jr. (left) and Pilot Scott J. Kelly look at a replacement computer for the Hubble Space Telescope. The payload hardware is in the Payload Hazardous Servicing Facility. Other members of the crew are Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland, and Jean-François Clervoy of France. Nicollier and Clervoy are with the European Space Agency. Mission STS-103 is a "call-up" due to the need to replace portions of the pointing system, the gyros, which have begun to fail on the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. The gyroscopes allow the telescope to point at stars, galaxies and planets. The STS-103 crew will not only replace gyroscopes, it will also replace a Fine Guidance Sensor and an older computer with the new enhanced model, an older data tape recorder with a solid state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. The scheduled launch date in October is under review

  18. Linking Nuclear Reactions and Nuclear Structure on the Way to the Drip Line

    NASA Astrophysics Data System (ADS)

    Dickhoff, Willem

    2012-10-01

    The present understanding of the role of short- and long-range physics in determining proton properties near the Fermi energy for stable closed-shell nuclei has relied on data from the (e,e'p) reaction. Hadronic tools to extract such spectroscopic information have been hampered by the lack of a consistent reaction description that provides unambiguous and undisputed results. The dispersive optical model (DOM), originally conceived by Claude Mahaux, provides a unified description of both elastic nucleon scattering and structure information related to single-particle properties below the Fermi energy. The DOM provides the starting point to provide a framework in which nuclear reactions and structure data can be analyzed consistently to provide unambiguous spectroscopic information including its asymmetry dependence. Recent extensions of this approach include the treatment of non-locality to describe experimental data like the nuclear charge density based on information of the spectral density below the Fermi energy, the application of the DOM ingredients to the description of transfer reactions, a comparison of the microscopic content of the nucleon self-energy based on Faddeev-RPA calculations emphasizing long-range correlations with DOM potentials, and a study of the relation between a self-energy which includes the effect of short-range correlations with DOM potentials. The most recent Dom implementation currently in progress abandons the constraint of local potentials completely to allow an accurate description of various properties of the nuclear ground state.

  19. STS-103 crew take part in CEIT

    NASA Technical Reports Server (NTRS)

    1999-01-01

    In the Payload Hazardous Servicing Facility, members of the STS-103 crew get instructions on use of rib clamps for the Shield Shell Replacement Fabric (SSRF) task on repair of the Hubble Space Telescope. The seven-member crew are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland, and Jean-Frangois Clervoy of France. Nicollier and Clervoy are with the European Space Agency. Mission STS-103 is a 'call-up' due to the need to replace portions of the pointing system, the gyros, which have begun to fail on the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. The gyroscopes allow the telescope to point at stars, galaxies and planets. The STS-103 crew will not only replace gyroscopes, it will also replace a Fine Guidance Sensor, an older computer with a new enhanced model, an older data tape recorder with a solid state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. The scheduled launch date in October is under review.

  20. STS-103 crew pose at 195-foot level of Fixed Service Structure

    NASA Technical Reports Server (NTRS)

    1999-01-01

    At the 195-foot level of the Fixed Service Structure on Launch Pad 39B, the STS-103 crew take a break from Terminal Countdown Demonstration Test (TCDT) activities. Standing from left to right are Mission Specialists Jean-Frangois Clervoy of France and Claude Nicollier of Switzerland, who are with the European Space Agency; Commander Curtis L. Brown Jr.; Pilot Scott J. Kelly; and Mission Specialists John M. Grunsfeld (Ph.D.), C. Michael Foale (Ph.D.) and Steven L. Smith. The TCDT provides the crew with the emergency egress training, opportunities to inspect their mission payloads in the orbiter's payload bay, and simulated countdown exercises. STS-103 is a 'call-up' mission due to the need to replace and repair portions of the Hubble Space Telescope, including the gyroscopes that allow the telescope to point at stars, galaxies and planets. The STS-103 crew will be replacing a Fine Guidance Sensor, an older computer with a new enhanced model, an older data tape recorder with a solid-state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The mission is targeted for launch Dec. 6 at 2:37 a.m. EST.

  1. Superphenix: Restarting, with emphasis on research

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    1994-04-01

    French Prime Minister Edouard Baladour announced on February 22 that the Superphenix fast reactor at Creys-Malville will be allowed to restart. Along with his industry minister, Gerard Longuet, and the environment minister, Michel Bamier, Baladour has accepted the recommendation for reissuance of an operating license submitted to the ministers in January by the nuclear installations safety directorate (DSIN). In announcing their approval for restart, the ministers emphasized that the reactor was to be used as a research and demonstration facility rather than a power station. In particular, they said it should be used to investigate the possibility of using fastmore » reactors as plutonium burners rather than breeders and for the incineration of other long-lived actinide wastes. This point was made also by DSIN Director Andre-Claude Lacoste in his recommendations, but appears to have been given more weight by the government ministers. The ministers also accepted the DSIN recommendation that restart be conditional on completion of improvements to fire protection systems for the secondary sodium coolant ducts. Baladour said that it would take several months to complete this work, but other sources have suggested that the reactor could be ready to operate this month. DSIN has also stipulated that the power level be limited for several months to around 50 percent of the plant`s 1200-MWe potential in order to check out all the systems carefully.« less

  2. [The production of optical glass in France and the experiences of Ruggiero Boscovich for the production of lead glass (Part One)].

    PubMed

    Proverbio, Edoardo

    The experiences that in 1758 led John Dollond to create the first achromatic telescope highlighted the serious difficulties related to the production of lenses with a correction for chromatic aberration. These difficulties were due to the lack of suitable tools for measuring the refraction index and for verifying the curvatures of the lenses of such optical instruments. To this was added what was perhaps the greatest difficulty: i.e., that of acquiring the kinds of glass, the so-called "common" (crown) glass and "lead" (flint) glass, of which the lenses had to be made. If the theoretical works of Alexis Clairaut, of Samuel Klingenstierna, and of Ruggiero Boscovich furnished the theoretical basis for producing such lenses, and subsequently--after Boscovich's discovery of the role of the eyepieces--for creating also achromatic eyepieces, the greatest challenge from the practical point of view was that of the availability of the flint glass. In this first part of the article there is then a study of the numerous attempts and directions pursued by Clairaut and his valid collaborators--Anthéaulme, George father and son, Charles François de l'Etang, and Claude Siméon Passemant--in order to find common glass and lead glass, and to produce the first achromatic lenses and binoculars in France. An analysis follows of the experiences conducted by Boscovich, first in Vienna, and then in Milan and Venice-Murano, addressed to the production of flint glass.

  3. KSC-99pp1098

    NASA Image and Video Library

    1999-09-02

    During a Crew Equipment Interface Test (CEIT), members of the STS-103 crew check out a portable foot restraint on the Flight Support System that will be used on the mission, repairing the Hubble Space Telescope. The seven-member crew comprises Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D), Claude Nicollier of Switzerland, and Jean-François Clervoy of France. Nicollier and Clervoy are with the European Space Agency. Mission STS-103 is a "call-up" due to the need to replace portions of the pointing system, the gyros, which have begun to fail on the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. The gyroscopes allow the telescope to point at stars, galaxies and planets. The STS-103 crew will not only replace gyroscopes, it will also replace a Fine Guidance Sensor and an older computer with a new enhanced model, an older data tape recorder with a solid-state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. The scheduled launch date in October is under review

  4. KSC-99pp1332

    NASA Image and Video Library

    1999-11-16

    In the bunker at Launch Pad 39B, STS-103 Pilot Scott J. Kelly (left) and Mission Specialist John M. Grunsfeld (Ph.D.) (right) try on oxygen masks during Terminal Countdown Demonstration Test (TCDT) activities. The TCDT provides the crew with emergency egress training, opportunities to inspect their mission payloads in the orbiter's payload bay, and simulated countdown exercises. Other crew members taking part are Commander Curtis L. Brown Jr. and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), and Jean-François Clervoy of France and Claude Nicollier of Switzerland, who are with the European Space Agency. STS-103 is a "call-up" mission due to the need to replace and repair portions of the Hubble Space Telescope, including the gyroscopes that allow the telescope to point at stars, galaxies and planets. The STS-103 crew will be replacing a Fine Guidance Sensor, an older computer with a new enhanced model, an older data tape recorder with a solid-state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The mission is targeted for launch Dec. 6 at 2:37 a.m. EST

  5. KSC-99pp1342

    NASA Image and Video Library

    1999-11-17

    Taking a break during emergency egress training at Launch Pad 39B are (left to right) STS-103 Mission Specialists Jean-François Clervoy of France, Claude Nicollier of Switzerland, Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, and Mission Specialists John M. Grunsfeld (Ph.D.), C. Michael Foale (Ph.D.) and Steven L. Smith. Clervoy and Nicollier are with the European Space Agency. The training is part of Terminal Countdown Demonstration Test (TCDT) activities that also include opportunities to inspect the mission payloads in the orbiter's payload bay and simulated countdown exercises. STS-103 is a "call-up" mission due to the need to replace and repair portions of the Hubble Space Telescope, including the gyroscopes that allow the telescope to point at stars, galaxies and planets. The STS-103 crew will be replacing a Fine Guidance Sensor, an older computer with a new enhanced model, an older data tape recorder with a solid-state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The mission is targeted for launch Dec. 6 at 2:37 a.m. EST

  6. KSC-99pp1346

    NASA Image and Video Library

    1999-11-17

    STS-103 Mission Specialist John M. Grunsfeld (Ph.D.) sits inside orbiter Discovery waiting for the start of a simulated countdown exercise. The simulation is part of Terminal Countdown Demonstration Test (TCDT) activities. The TCDT also provides the crew with emergency egress training and opportunities to inspect their mission payload in the orbiter's payload bay. Other crew members taking part in the TCDT are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), Jean-François Clervoy of France, and Claude Nicollier of Switzerland. Clervoy and Nicollier are with the European Space Agency. STS-103 is a "call-up" mission due to the need to replace and repair portions of the Hubble Space Telescope, including the gyroscopes that allow the telescope to point at stars, galaxies and planets. The STS-103 crew will be replacing a Fine Guidance Sensor, an older computer with a new enhanced model, an older data tape recorder with a solid-state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The mission is targeted for launch Dec. 6 at 2:37 a.m. EST

  7. KSC-99pp1100

    NASA Image and Video Library

    1999-09-03

    In the Orbiter Processing Facility (OPF) bay 1, STS-103 Commander Curtis L. Brown Jr. sits in the command seat of the orbiter Discovery, inspecting the window. Brown and other crew members are at KSC to take part in a Crew Equipment Interface Test. The rest of the crew are Pilot Scott J. Kelly, and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland, and Jean-François Clervoy of France. Nicollier and Clervoy are with the European Space Agency. Mission STS-103 is a "call-up" due to the need to replace portions of the pointing system, the gyros, which have begun to fail on the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. The gyroscopes allow the telescope to point at stars, galaxies and planets. The STS-103 crew will not only replace gyroscopes, it will also replace a Fine Guidance Sensor and an older computer with a new enhanced model, an older data tape recorder with a solid-state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. The scheduled launch date in October is under review

  8. KSC-99pp1347

    NASA Image and Video Library

    1999-11-17

    STS-103 Mission Commander Curtis L. Brown Jr. sits inside orbiter Discovery waiting for the start of a simulated countdown exercise. The simulation is part of Terminal Countdown Demonstration Test (TCDT) activities. The TCDT also provides the crew with emergency egress training and opportunities to inspect their mission payload in the orbiter's payload bay. Other crew members taking part in the TCDT are Pilot Scott J. Kelly, and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Jean-François Clervoy of France, and Claude Nicollier of Switzerland. Clervoy and Nicollier are with the European Space Agency. STS-103 is a "call-up" mission due to the need to replace and repair portions of the Hubble Space Telescope, including the gyroscopes that allow the telescope to point at stars, galaxies and planets. The STS-103 crew will be replacing a Fine Guidance Sensor, an older computer with a new enhanced model, an older data tape recorder with a solid-state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The mission is targeted for launch Dec. 6 at 2:37 a.m. EST

  9. KSC-99pp1088

    NASA Image and Video Library

    1999-09-02

    In the Payload Hazardous Servicing Facility, members of the STS-103 crew get instructions on use of rib clamps for the Shield Shell Replacement Fabric (SSRF) task on repair of the Hubble Space Telescope. The seven-member crew are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland, and Jean-François Clervoy of France. Nicollier and Clervoy are with the European Space Agency. Mission STS-103 is a "call-up" due to the need to replace portions of the pointing system, the gyros, which have begun to fail on the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. The gyroscopes allow the telescope to point at stars, galaxies and planets. The STS-103 crew will not only replace gyroscopes, it will also replace a Fine Guidance Sensor, an older computer with a new enhanced model, an older data tape recorder with a solid state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. The scheduled launch date in October is under review

  10. KSC-99pp1328

    NASA Image and Video Library

    1999-11-16

    At Launch Pad 39B, STS-103 Commander Curtis L. Brown Jr. introduces the rest of the crew: (left to right) Pilot Scott J. Kelly and Mission Specialists Steven L. Smith, Jean-François Clervoy of France, who is with the European Space Agency (ESA), John M. Grunsfeld (Ph.D.), C. Michael Foale (Ph.D.), and Claude Nicollier of Switzerland, who is also with ESA. As a preparation for launch, they have been participating in Terminal Countdown Demonstration Test (TCDT) activities at KSC. The TCDT provides the crew with emergency egress training, opportunities to inspect their mission payloads in the orbiter's payload bay, and simulated countdown exercises. STS-103 is a "call-up" mission due to the need to replace and repair portions of the Hubble Space Telescope, including the gyroscopes that allow the telescope to point at stars, galaxies and planets. The STS-103 crew will be replacing a Fine Guidance Sensor, an older computer with a new enhanced model, an older data tape recorder with a solid-state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The mission is targeted for launch Dec. 6 at 2:37 a.m. EST

  11. STS-103 crew take part in CEIT in the orbiter Discovery

    NASA Technical Reports Server (NTRS)

    1999-01-01

    In the mid-deck of the orbiter Discovery, STS-103 crew Commander Curtis L. Brown Jr. and Pilot Scott J. Kelly check out part of the equipment to be flown on the mission, the repair and upgrade of the Hubble Space Telescope. They are at KSC taking part in a Crew Equipment Interface Test along with other crew members Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland, and Jean-Fran'''ois Clervoy of France. Nicollier and Clervoy are with the European Space Agency. Mission STS-103 is a 'call-up' due to the need to replace portions of the pointing system, the gyros, which have begun to fail on the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. The gyroscopes allow the telescope to point at stars, galaxies and planets. The STS-103 crew will not only replace gyroscopes, it will also replace a Fine Guidance Sensor and an older computer with a new enhanced model, an older data tape recorder with a solid-state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. The scheduled launch date in October is under review.

  12. Monocarboxylate transporters in the brain and in cancer.

    PubMed

    Pérez-Escuredo, Jhudit; Van Hée, Vincent F; Sboarina, Martina; Falces, Jorge; Payen, Valéry L; Pellerin, Luc; Sonveaux, Pierre

    2016-10-01

    Monocarboxylate transporters (MCTs) constitute a family of 14 members among which MCT1-4 facilitate the passive transport of monocarboxylates such as lactate, pyruvate and ketone bodies together with protons across cell membranes. Their anchorage and activity at the plasma membrane requires interaction with chaperon protein such as basigin/CD147 and embigin/gp70. MCT1-4 are expressed in different tissues where they play important roles in physiological and pathological processes. This review focuses on the brain and on cancer. In the brain, MCTs control the delivery of lactate, produced by astrocytes, to neurons, where it is used as an oxidative fuel. Consequently, MCT dysfunctions are associated with pathologies of the central nervous system encompassing neurodegeneration and cognitive defects, epilepsy and metabolic disorders. In tumors, MCTs control the exchange of lactate and other monocarboxylates between glycolytic and oxidative cancer cells, between stromal and cancer cells and between glycolytic cells and endothelial cells. Lactate is not only a metabolic waste for glycolytic cells and a metabolic fuel for oxidative cells, but it also behaves as a signaling agent that promotes angiogenesis and as an immunosuppressive metabolite. Because MCTs gate the activities of lactate, drugs targeting these transporters have been developed that could constitute new anticancer treatments. This article is part of a Special Issue entitled: Mitochondrial Channels edited by Pierre Sonveaux, Pierre Maechler and Jean-Claude Martinou. Copyright © 2016 The Authors. Published by Elsevier B.V. All rights reserved.

  13. X-rays Provide a New Way to Investigate Exploding Stars

    NASA Astrophysics Data System (ADS)

    2007-05-01

    exhausted. The duration of this X-ray emission traces the amount of material left on the white dwarf after the nova explosion. Optical Image of Andromeda Galaxy (M31) Optical Image of Andromeda Galaxy (M31) A well determined start time of the optical nova outburst and the X-ray turn-on and turn-off times are therefore important benchmarks for replication in computer models of novae. Whilst monitoring the M31 novae, frequently over several months, for the appearance and subsequent disappearance of the X-rays, Pietsch made an important discovery. Some novae start to emit X-rays and then turn them off again within just a few months. "These novae are a new class. They would have been overlooked before," says Pietsch. That's because previous surveys looked only every six months or so. Within that time, the fast X-ray novae could have blinked both on and off. In addition to discovering the short-lived ones, the new survey also confirms that other novae generate X-rays over a much longer time. XMM-Newton detected seven novae that were still shining X-rays into space, up to a decade after the original eruption. The differing lengths of times are thought to reflect the masses of the white dwarfs at the heart of the nova explosion. The fastest evolving novae are thought to be those coming from the most massive white dwarfs. To investigate further, the team have been awarded more XMM-Newton and Chandra observing time. They now plan to monitor M31's novae every ten days for several months, starting in November 2007 to glean more information about these puzzling stellar explosions. Notes for editors: X-ray monitoring of optical novae in M31 from July 2004 to February 2005 by W. Pietsch et al. is published in Astronomy and Astrophysics, 465, 375-392 (2007). For more information: Wolfgang Pietsch wnp@mpe.mpg.de Norbert Schartel Norbert.Schartel@sciops.esa.int

  14. Jets Spout Far Closer to Black Hole Than Thought, Scientists Say

    NASA Astrophysics Data System (ADS)

    2004-01-01

    opportunity to study the origin, evolution, and long-term behavior of jets because the X rays come from a region very close to the black hole. Of the hundreds of jets observed in the radio and X-ray bands, this is the only one for which we have a solid statement that it contains atomic nuclei and for which we are sure of the internal temperature and density." Supermassive black holes with jets, such as quasars, might display similar behavior, but they are so massive and so distant that changes cannot be observed because time scales are too long. Thus SS 433 serves as a laboratory to study the jet phenomenon "close to home," Marshall said. As such, further Chandra observations are planned. Collaborators on the investigation were Claude Canizares, Julie Kane, and Norbert Schulz, all of MIT. For images, refer to http://space.mit.edu/~hermanm/ss433.html.

  15. Diagnosis, Prevalence, Awareness, Treatment, Prevention, and Control of Hypertension in Cameroon: Protocol for a Systematic Review and Meta-Analysis of Clinic-Based and Community-Based Studies.

    PubMed

    Kuate Defo, Barthelemy; Mbanya, Jean Claude; Tardif, Jean-Claude; Ekundayo, Olugbemiga; Perreault, Sylvie; Potvin, Louise; Cote, Robert; Kengne, Andre Pascal; Choukem, Simeon Pierre; Assah, Felix; Kingue, Samuel; Richard, Lucie; Pongou, Roland; Frohlich, Katherine; Saji, Jude; Fournier, Pierre; Sobngwi, Eugene; Ridde, Valery; Dubé, Marie-Pierre; De Denus, Simon; Mbacham, Wilfred; Lafrance, Jean-Philippe; Nsagha, Dickson Shey; Mampuya, Warner; Dzudie, Anastase; Cloutier, Lyne; Zarowsky, Christina; Tanya, Agatha; Ndom, Paul; Hatem, Marie; Rey, Evelyne; Roy, Louise; Borgès Da Silva, Roxane; Dagenais, Christian; Todem, David; Weladji, Robert; Mbanya, Dora; Emami, Elham; Njoumemi, Zakariaou; Monnais, Laurence; Dubois, Carl-Ardy

    2017-05-29

    independently search, screen, extract data, and assess the quality of selected studies using suitable tools. Selected studies will be analyzed by narrative synthesis, meta-analysis, or both, depending on the nature of the data retrieved in line with the review objectives. This review is part of an ongoing research program on disease prevention and control in the context of the dual burden of communicable and noncommunicable diseases in Africa. The first results are expected in 2017. This review will provide a comprehensive assessment of the burden of hypertension and control measures that have been designed and implemented in Cameroon. Findings will form the knowledge base relevant to stakeholders across the health system and researchers who are involved in hypertension prevention and control in the community and clinic settings in Cameroon, as a yardstick for similar African countries. PROSPERO registration number: CRD42017054950; http://www.crd.york.ac.uk/PROSPERO/ display_record.asp?ID=CRD42017054950 (Archived by WebCite at http://www.webcitation.org/6qYSjt9Jc). ©Barthelemy Kuate Defo, Jean Claude Mbanya, Jean-Claude Tardif, Olugbemiga Ekundayo, Sylvie Perreault, Louise Potvin, Robert Cote, Andre Pascal Kengne, Simeon Pierre Choukem, Felix Assah, Samuel Kingue, Lucie Richard, Roland Pongou, Katherine Frohlich, Jude Saji, Pierre Fournier, Eugene Sobngwi, Valery Ridde, Marie-Pierre Dubé, Simon De Denus, Wilfred Mbacham, Jean-Philippe Lafrance, Dickson Shey Nsagha, Warner Mampuya, Anastase Dzudie, Lyne Cloutier, Christina Zarowsky, Agatha Tanya, Paul Ndom, Marie Hatem, Evelyne Rey, Louise Roy, Roxane Borgès Da Silva, Christian Dagenais, David Todem, Robert Weladji, Dora Mbanya, Elham Emami, Zakariaou Njoumemi, Laurence Monnais, Carl-Ardy Dubois. Originally published in JMIR Research Protocols (http://www.researchprotocols.org), 29.05.2017.

  16. Hubble Space Telescope Servicing begins.

    NASA Astrophysics Data System (ADS)

    1993-12-01

    The day's work began when astronauts Story Musgrave and Jeff Hoffman stepped out into the cargo bay at 9h41 pm CST, Saturday (4h41 am CET, Sunday). They immediately set to work replacing two gyroscope assemblies, known as the Rate Sensor Units, two associated electronics boxes, called Electronic Control Units, and eight electrical fuse plugs. The work was completed ahead of schedule, but the astronauts had trouble closing the doors of the compartment housing the gyros and took over an hour to get them shut. The astronauts also prepared equipment for the replacement of the solar arrays. "The feeling down here is one of great satisfaction for a tremendous job today" said spacecraft communicator Greg Harbaugh in mission control. "We are very proud of the work that you all did and we are very confident in the continued success of the mission. Everything is going great and tomorrow is going to be another great day". ESA astronaut Claude Nicollier played a vital role during the spacewalk moving the astronauts and their equipment around the cargo bay with the shuttle's robot arm. The Hubble Space Telescope servicing mission features more robot arm operations than any other shuttle flight. The telescope's left-hand solar array was rolled up successfully at 6h24 am CST (1h24 pm CET). The 11-tonne observatory was rotated 180 degrees on its turntable before commands were sent to retract the second array at 8h23 am CST (3h23 pm CET). The crew stopped the retraction when it appeared the system may have jammed. Mission control instructed the crew to jettison the array, a procedure that they have trained for. Tomorrow astronauts Kathy Thornton and Tom Akers will make a six-hour spacewalk to jettison the troublesome wing, store the other in the cargo bay, and install two new panels supplied by ESA. The second set of arrays feature thermal shields and a modified thermal compensation system to prevent the flexing that affected the first pair. The Hubble Space Telescope was plucked

  17. Ethical Implications of the Mild Encephalitis Hypothesis of Schizophrenia

    PubMed Central

    Riedmüller, Rita; Müller, Sabine

    2017-01-01

    Schizophrenia is a serious mental disease with a high mortality rate and severe social consequences. Due to insufficient knowledge about its etiopathogenesis, curative treatments are not available. One of the most promising new research concepts is the mild encephalitis hypothesis of schizophrenia, developed mainly by Karl Bechter and Norbert Müller. According to this hypothesis, a significant subgroup of schizophrenia patients suffer from a mild, but chronic, form of encephalitis with markedly different etiologies ranging from viral infections, traumas to autoimmune diseases. This inflammatory process is thought to occur in the beginning or during the course of the disease. In this article, we investigate the consequences of the mild encephalitis hypothesis of schizophrenia for the scientific community, and evaluate these consequences ethically. The mild encephalitis hypothesis implies that schizophrenia would no longer be considered an incurable psychiatric disorder. Instead, it would be considered a chronic, but treatable, neurological disease. This paradigm shift would doubtlessly have significant consequences: (1) major reforms would be necessary in the theoretical conceptualization of schizophrenia, which would challenge the psychiatric diagnostic systems, Diagnostic and Statistical Manual of Mental Disorders version 5 and ICD-10. (2) Psychotic patients should be treated in interdisciplinary teams, optimally in neuropsychiatric units; additionally, specialists for endocrinology, diabetology, and cardiology should be consulted for the frequently occuring somatic comorbidities. (3) Current diagnostic procedures and (4) therapies would have to be modified significantly. (5) There might be repercussions for the pharmaceutical industry as well: first, because old drugs with expired patent protection could partly replace expensive drugs and, second, because there would be a demand for the development of new anti-inflammatory drugs. (6) Legal evaluation of

  18. Hurricane Odile

    NASA Image and Video Library

    2017-12-08

    At about 10:45 p.m. Mountain Daylight Time (MDT) on September 14, 2014, Hurricane Odile made landfall as a Category 3 storm near Cabo San Lucas, Mexico. According to the U.S. National Hurricane Center, Odile arrived with wind speeds of 110 knots (204 kilometers or 127 miles per hour). The storm tied Olivia (1967) as the strongest hurricane to make landfall in the state of Baja California Sur in the satellite era. The Moderate Resolution Imaging Spectroradiometer (MODIS) on NASA’s Terra satellite acquired this natural-color view of the storm at about noon MDT on September 14, when it was still southeast of the Baja California peninsula. Unisys Weather reported that the Category 4 storm had maximum sustained wind speeds of 115 knots (213 kilometers per hour) at the time. Odile had weakened to a Category 2 hurricane by 6 a.m. MDT on September 15. The storm was expected to continue weakening as it moved up the peninsula and over the area’s rough terrain, according to weather blogger Jeff Masters. Meteorologists noted that while damaging winds posed the biggest threat in the short term, inland areas of the U.S. Southwest could face heavy rainfall by September 16. The rain expected from Odile came one week after the U.S. Southwest experienced flash floods from the remnants of Hurricane Norbert. According to weather and climate blogger Eric Holthaus, those floods did little to relieve the area’s ongoing drought. NASA image by Jeff Schmaltz, LANCE/EOSDIS Rapid Response. Caption by Kathryn Hansen. Instrument(s): Terra - MODIS Read more: earthobservatory.nasa.gov/IOTD/view.php?id=84378&eocn... NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on

  19. Bavarian Prime Minister to Visit la Silla

    NASA Astrophysics Data System (ADS)

    1997-03-01

    The Bavarian Prime Minister, Dr. Edmund Stoiber , is currently visiting a number of countries in South America. He is accompanied by a high-ranking delegation of representatives of Bavarian politics and industry. During this trip, the Bavarian delegation will visit the Republic of Chile, arriving in Santiago de Chile on Sunday, March 9, 1997. On the same day, Dr. Stoiber and most other members of the delegation, on the invitation of the Director General of ESO, Professor Riccardo Giacconi, will visit the ESO La Silla Observatory , located in an isolated area in the Atacama desert some 600 km north of the Chilean capital. ESO, the European Organisation for Astronomy, with Headquarters in Garching near Munich in Bavaria, welcomes this opportunity to present its high-tech research facilities to Dr. Stoiber and leaders of the Bavarian industry. During the visit, the delegation will learn about the various front-line research projects, now being carried out by astronomers from Germany and other ESO member countries with the large telescopes at La Silla. There will also be a presentation of the ESO VLT project , which will become the world's largest optical astronomical telescope, when it is ready a few years from now. The delegation will be met by the Director of the La Silla Observatory, Dr. Jorge Melnick and his scientific-technical staff which includes several members of German nationality. Also present will be ESO's Head of Administration, Dr. Norbert König (Garching) and the General Manager of ESO in Chile, Mr. Daniel Hofstadt. More information about this visit and the ESO facilities is available from the ESO Education and Public Relations Department (Tel.: +49-89-32006-276; Fax.: +49-89-3202362; email: ips@eso.org; Web: http://www.eso.org../../../epr/ ). Diese Pressemitteilung ist auch in einer Deutschen Fassung vorhanden. How to obtain ESO Press Information ESO Press Information is made available on the World-Wide Web (URL: http://www.eso.org../). ESO Press

  20. STS-103 crew take part in CEIT in OPF 1

    NASA Technical Reports Server (NTRS)

    1999-01-01

    In the Orbiter Processing Facility (OPF) bay 1, STS-103 crew members check out equipment to be used on planned Extravehicular Activities (EVAs) on the mission for repair of the Hubble Space Telescope. They are taking part in a Crew Equipment Interface Test (CEIT) at KSC. From left are Mission Specialists C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland, and Steven L. Smith. Other crew members at KSC for the CEIT are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, and Jean-Frangois Clervoy of France. Nicollier and Clervoy are with the European Space Agency. Mission STS-103 is a 'call-up' due to the need to replace portions of the pointing system, the gyros, which have begun to fail on the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. The gyroscopes allow the telescope to point at stars, galaxies and planets. The STS-103 crew will not only replace gyroscopes, it will also replace a Fine Guidance Sensor and an older computer with a new enhanced model, an older data tape recorder with a solid-state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. The scheduled launch date in October is under review.

  1. STS-103 crew wait inside Discovery for simulated countdown exercise

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Strapped into their seats inside the orbiter Discovery for a simulated countdown exercise are (left to right) STS-103 Mission Specialists Claude Nicollier of Switzerland, Steven L. Smith, and C. Michael Foale (Ph.D.). The simulation is part of Terminal Countdown Demonstration Test (TCDT) activities. The TCDT also provides the crew with emergency egress training and opportunities to inspect their mission payload in the orbiter's payload bay. Other crew members taking part in the TCDT are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, and Mission Specialists C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), and Jean-Fran'''ois Clervoy of France. Clervoy and Nicollier are with the European Space Agency. STS-103 is a 'call-up' mission due to the need to replace and repair portions of the Hubble Space Telescope, including the gyroscopes that allow the telescope to point at stars, galaxies and planets. The STS-103 crew will be replacing a Fine Guidance Sensor, an older computer with a new enhanced model, an older data tape recorder with a solid-state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The mission is targeted for launch Dec. 6 at 2:37 a.m. EST.

  2. STS-103 crew wait inside Discovery for simulated countdown exercise

    NASA Technical Reports Server (NTRS)

    1999-01-01

    STS-103 Mission Specialists Jean-Fran'''ois Clervoy of France takes his seat inside the Space Shuttle Discovery during a practice launch countdown, part of Terminal Countdown Demonstration Test (TCDT) activities, while astronaut David 'Doc' Brown checks him out. The TCDT also provides the crew with emergency egress training and opportunities to inspect their mission payload in the orbiter's payload bay. Other crew members taking part in the TCDT are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), and Claude Nicollier of Switzerland. Clervoy and Nicollier are with the European Space Agency. STS-103 is a 'call-up' mission due to the need to replace and repair portions of the Hubble Space Telescope, including the gyroscopes that allow the telescope to point at stars, galaxies and planets. The STS-103 crew will be replacing a Fine Guidance Sensor, an older computer with a new enhanced model, an older data tape recorder with a solid-state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The mission is targeted for launch Dec. 6 at 2:37 a.m. EST.

  3. STS-103 crew learn about use of slideware basket at Pad 39B

    NASA Technical Reports Server (NTRS)

    1999-01-01

    At the slidewire area of Launch Pad 39B, the STS-103 crew listen to use of the emergency egress equipment. From left are the trainer, with crew members Mission Specialists Steven L. Smith, Jean-Frangois Clervoy of France, Claude Nicollier of Switzerland, John M. Grunsfeld (Ph.D.), Pilot Steven J. Kelly, C. Michael Foale (Ph.D.), and (kneeling) Commander Curtis L. Brown Jr. Clervoy and Nicollier are both with the European Space Agency. As a preparation for launch, the crew have been participating in Terminal Countdown Demonstration Test (TCDT) activities at KSC. The TCDT provides the crew with emergency egress training, opportunities to inspect their mission payloads in the orbiter's payload bay, and simulated countdown exercises. STS-103 is a 'call-up' mission due to the need to replace and repair portions of the Hubble Space Telescope, including the gyroscopes that allow the telescope to point at stars, galaxies and planets. The STS-103 crew will be replacing a Fine Guidance Sensor, an older computer with a new enhanced model, an older data tape recorder with a solid-state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The mission is targeted for launch Dec. 6 at 2:37 a.m. EST.

  4. STS-103 crew take part in CEIT in PHSF

    NASA Technical Reports Server (NTRS)

    1999-01-01

    During a Crew Equipment Interface Test in the Payload Hazardous Servicing Facility, members of the STS-103 crew check out the Flight Support System (FSS)from above and below. The FSS is part of the primary payload on the mission to repair the Hubble Space Telescope. The seven-member crew comprises Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D), Claude Nicollier of Switzerland, and Jean-Frangois Clervoy of France. Nicollier and Clervoy are with the European Space Agency. Mission STS-103 is a 'call-up' due to the need to replace portions of the pointing system, the gyros, which have begun to fail on the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. The gyroscopes allow the telescope to point at stars, galaxies and planets. The STS-103 crew will not only replace gyroscopes, it will also replace a Fine Guidance Sensor and an older computer with a new enhanced model, an older data tape recorder with a solid-state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. The scheduled launch date in October is under review.

  5. Systems biology of eukaryotic superorganisms and the holobiont concept.

    PubMed

    Kutschera, Ulrich

    2018-06-14

    The founders of modern biology (Jean Lamarck, Charles Darwin, August Weismann etc.) were organismic life scientists who attempted to understand the morphology and evolution of living beings as a whole (i.e., the phenotype). However, with the emergence of the study of animal and plant physiology in the nineteenth century, this "holistic view" of the living world changed and was ultimately replaced by a reductionistic perspective. Here, I summarize the history of systems biology, i.e., the modern approach to understand living beings as integrative organisms, from genotype to phenotype. It is documented that the physiologists Claude Bernard and Julius Sachs, who studied humans and plants, respectively, were early pioneers of this discipline, which was formally founded 50 years ago. In 1968, two influential monographs, authored by Ludwig von Bertalanffy and Mihajlo D. Mesarović, were published, wherein a "systems theory of biology" was outlined. Definitions of systems biology are presented with reference to metabolic or cell signaling networks, analyzed via genomics, proteomics, and other methods, combined with computer simulations/mathematical modeling. Then, key insights of this discipline with respect to epiphytic microbes (Methylobacterium sp.) and simple bacteria (Mycoplasma sp.) are described. The principles of homeostasis, molecular systems energetics, gnotobiology, and holobionts (i.e., complexities of host-microbiota interactions) are outlined, and the significance of systems biology for evolutionary theories is addressed. Based on the microbe-Homo sapiens-symbiosis, it is concluded that human biology and health should be interpreted in light of a view of the biomedical sciences that is based on the holobiont concept.

  6. The XIIIth International Physiological Congress in Boston in 1929: American physiology comes of age.

    PubMed

    Rall, Jack A

    2016-03-01

    In the 19th century, the concept of experimental physiology originated in France with Claude Bernard, evolved in Germany stimulated by the teaching of Carl Ludwig, and later spread to Britain and then to the United States. The goal was to develop a physicochemical understanding of physiological phenomena. The first International Physiological Congress occurred in 1889 in Switzerland with an emphasis on experimental demonstrations. The XIIIth Congress, the first to be held outside of Europe, took place in Boston, MA, in 1929. It was a watershed meeting and indicated that American physiology had come of age. Meticulously organized, it was the largest congress to date, with over 1,200 participants from more than 40 countries. Getting to the congress was a cultural adventure, especially for the 400 scientists and their families from over 20 European countries, who sailed for 10 days on the S.S. Minnekahda. Many of the great physiologists of the world were in attendance, including 22 scientists who were either or would become Nobel Laureates. There were hundreds of platform presentations and many experimental demonstrations. The meeting was not without controversy as a conflict, still not completely settled, arose over the discovery of ATP. After the meeting, hundreds of participants made a memorable trip to the Marine Biological Laboratory at Woods Hole, MA, which culminated in a "good old fashioned Cape Cod Clambake." Although not as spectacular as the 1929 congress, the physiological congresses have continued with goals similar to those established more than a century ago. Copyright © 2016 The American Physiological Society.

  7. STS-61 crew utilizing Virtual Reality in training for HST repair mission

    NASA Image and Video Library

    1993-06-11

    Astronaut Jeffrey A. Hoffman, one of four crewmembers for STS-61 that will conduct scheduled spacewalks during the flight, wears a special helmet and gloves designed to assist in proper positioning near the telescope while on the end of the robot arm. Crewmembers are utilizing a new virtual reality training aid which assists in refining positioning patterns for Space Shuttle Endeavour's Remote Manipulator System (RMS) (36890); Astronaut Claude Nicollier looks at a computer display of the Shuttle's robot arm movements as Thomas D. Akers and Kathryn C. Thornton, mission specialists look on. Nicollier will be responsible for maneuvering the astronauts while they stand in a foot restraint on the end of the RMS arm (36891,36894); Hoffman wears a special helmet and gloves designed to assist in proper positioning near the telescope while on the end of the robot arm (35892); Nicollier looks at a computer display of the Shuttle's robot arm movements as Akers looks on (36893); While (l-r) Astronauts Kenneth Bowersox, Kathryn Thornton, Richard O. Covey and Thomas D. Akers watch, Nicollier moves the Robot arm to desired locations in the Shuttle's payload bay using the Virtual Reality program (36895); Bowersox takes his turn maneuvering the RMS while mission specialist Hoffman, wearing the Virtual Reality helmet, follows his own progress on the end of the robot arm. Crewmembers participating during the training session are (l-r) Astronauts Akers, Hoffman, Bowersox, Nicollier, Covey, and Thornton. In the background, David Homan, an engineer in the JSC Engineering Directorate's Automation and Robotics Division, looks on (36896).

  8. STS-103 crew take part in CEIT in PHSF

    NASA Technical Reports Server (NTRS)

    1999-01-01

    During a Crew Equipment Interface Test in the Payload Hazardous Servicing Facility, members of the STS-103 crew check out the top of the Flight Support System (FSS) for the mission, the repair and upgrade of the Hubble Space Telescope. The number one in the foreground refers to one of the berthing latches on the FSS. The seven-member crew comprises Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D), Claude Nicollier of Switzerland, and Jean-Frangois Clervoy of France. Nicollier and Clervoy are with the European Space Agency. Mission STS-103 is a 'call-up' due to the need to replace portions of the pointing system, the gyros, which have begun to fail on the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. The gyroscopes allow the telescope to point at stars, galaxies and planets. The STS-103 crew will not only replace gyroscopes, it will also replace a Fine Guidance Sensor and an older computer with a new enhanced model, an older data tape recorder with a solid-state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. The scheduled launch date in October is under review.

  9. KSC-99pp1506

    NASA Image and Video Library

    1999-12-27

    After landing at the Shuttle Landing Facility, the STS-103 crew looks over the orbiter Discovery. In the foreground, from left, are Mission Specialist Jean-Francois Clervoy of France, Pilot Scott J. Kelly, Commander Curtis L. Brown Jr. and Mission Specialist C. Michael Foale (Ph.D.); behind them, from left, are Mission Specialists Steven L. Smith and Claude Nicollier of Switzerland. The remaining crew member (not shown) is Mission Specialist John M. Grunsfeld (Ph.D.). The crew of seven completed a successful eight-day mission to service the Hubble Space Telescope, spending the Christmas holiday in space in order to accomplish their mission before the end of 1999. During the mission, Discovery's four space-walking astronauts, Smith, Foale, Grunsfeld and Nicollier, spent 24 hours and 33 minutes upgrading and refurbishing Hubble, making it more capable than ever to renew its observations of the universe. Mission objectives included replacing gyroscopes and an old computer, installing another solid state recorder, and replacing damaged insulation in the telescope. Hubble was released from the end of Discovery's robot arm on Christmas Day. Main gear touchdown was at 7:00:47 p.m. EST. Nose gear touchdown occurred at 7:00:58 p.m. EST and wheel stop at 7:01:34 p.m. EST. This was the 96th flight in the Space Shuttle program and the 27th for the orbiter Discovery. The landing was the 20th consecutive Shuttle landing in Florida and the 13th night landing in Shuttle program history

  10. Exploring the Rays of Debussy

    NASA Image and Video Library

    2017-12-08

    NASA image acquired: March 29, 2011 Bright rays, consisting of impact ejecta and secondary craters, spread across this NAC image and radiate from Debussy crater, located at the top. The image, acquired yesterday during the first orbit for which MDIS was imaging, shows just a small portion of Debussy's large system of rays in greater detail than ever previously seen. Images acquired during MESSENGER's second Mercury flyby showed that Debussy's rays extend for hundreds of kilometers across Mercury's surface. Debussy crater was named in March 2010, in honor of the French composer Claude Debussy (1862-1918). On March 17, 2011 (March 18, 2011, UTC), MESSENGER became the first spacecraft to orbit the planet Mercury. The mission is currently in its commissioning phase, during which spacecraft and instrument performance are verified through a series of specially designed checkout activities. In the course of the one-year primary mission, the spacecraft's seven scientific instruments and radio science investigation will unravel the history and evolution of the Solar System's innermost planet. Visit the Why Mercury? section of this website to learn more about the science questions that the MESSENGER mission has set out to answer. Credit: NASA/Johns Hopkins University Applied Physics Laboratory/Carnegie Institution of Washington NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Join us on Facebook

  11. Intracellular trafficking pathways of Cx43 gap junction channels.

    PubMed

    Epifantseva, Irina; Shaw, Robin M

    2018-01-01

    Gap Junction (GJ) channels, including the most common Connexin 43 (Cx43), have fundamental roles in excitable tissues by facilitating rapid transmission of action potentials between adjacent cells. For instance, synchronization during each heartbeat is regulated by these ion channels at the cardiomyocyte cell-cell border. Cx43 protein has a short half-life, and rapid synthesis and timely delivery of those proteins to particular subdomains are crucial for the cellular organization of gap junctions and maintenance of intracellular coupling. Impairment in gap junction trafficking contributes to dangerous complications in diseased hearts such as the arrhythmias of sudden cardiac death. Of recent interest are the protein-protein interactions with the Cx43 carboxy-terminus. These interactions have significant impact on the full length Cx43 lifecycle and also contribute to trafficking of Cx43 as well as possibly other functions. We are learning that many of the known non-canonical roles of Cx43 can be attributed to the recently identified six endogenous Cx43 truncated isoforms which are produced by internal translation. In general, alternative translation is a new leading edge for proteome expansion and therapeutic drug development. This review highlights recent mechanisms identified in the trafficking of gap junction channels, involvement of other proteins contributing to the delivery of channels to the cell-cell border, and understanding of possible roles of the newly discovered alternatively translated isoforms in Cx43 biology. This article is part of a Special Issue entitled: Gap Junction Proteins edited by Jean Claude Herve. Copyright © 2017 Elsevier B.V. All rights reserved.

  12. [From Nebuchadnezzar to the randomized controlled trial--milestones in the development of clinical research].

    PubMed

    Oberbaum, Menachem; Lysy, Joseph; Gropp, Cornelius

    2011-08-01

    The first clinical experiment is described in the bible: The prophet Daniel is reported being nourished during ten days by seeds and water only, in order to check if his physical state would deteriorate as a result of this minimal nutrition. In the 15th century, French surgeon Ambroise Parí experimented with a mixture of turpentine, egg protein and rose oil to treat combat wounds, which is thought to be the first clinical study to be reported. In the 19th century British scientist James Lind designed the first controlled prospective study with parallel groups, proving that ingesting citrus fruit prevents scurvy. A short time afterwards British scientist John Haygarth was the first to use a placebo drug in a clinical study. Important work on placebo was conducted by the American scientists Austin Flint and later by Henry K. Beecher, who showed that placebo itself has biological properties. The importance of comparative studies was first understood by French psychologist CLaude Bernard. He is considered the founder of the modern scientific method based on observation, analysis of data and examination of hypotheses. Bernard's work was based on the work of fellow Frenchman Pierre Charles Alexandre Louis, who is justly considered a founding father of modern epidemiology, and who was the first to use statistics in clinical experiments. Random distributions in clinical studies were reported even before this time, for instance in the work of the Flemish physician Johannes Baptista van Helmont. Danish Nobel prize winner Johannes Fibiger pioneered the use of selection bias in his work with diphtheria serum.

  13. What do we do, if some of the MICE magnets can't be kept cold using the two-stage coolers?

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Green, Michael A.

    2011-01-26

    Tests of the spectrometer solenoids have not been encouraging in terms of keeping the magnets cold using three 1.5 W (at 4.2 K) coolers. The spectrometer solenoids are being rebuilt with additional cooling capacity at 4.2 K. It is hoped that there will be sufficient 4.2 K cooling to keep the magnets cold. The spectrometer solenoids can be kept cold using liquid helium (up to a boil-off of 20 liters per day). This option does not apply for the other magnets in the MICE cooling channel, because there is not enough liquid helium storage within the magnet cold mass. Itmore » is important that the MICE collaboration ask the question, “How do we keep the MICE cooling channel magnets cold, if there isn’t sufficient cooling from the 4.2 K coolers?” This report discusses the cooling requirements at both 40 K and 4.2 K for all three types of MICE cooling channel magnets. This report discusses the steps that must be taken in the magnet fabrication to permit the magnets to be cooled using a small (20 to 40 W) external 4.2 K Claude cycle refrigerator. One must also ask the question as to whether there is enough excess capacity in the decay solenoid refrigerator to cool some of the MICE magnets. A plan for cooling the magnets using a Linde 1400 series refrigerator is presented. A plan for increasing the 4.4 K refrigeration from the existing decay solenoid refrigerator is also presented.« less

  14. Overview of Air Liquide refrigeration systems between 1.8 K and 200 K

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gondrand, C.; Durand, F.; Delcayre, F.

    Cryogenic refrigeration systems are necessary for numerous applications. Gas purification and distillation require temperatures between 15 K and 200 K depending on the application, space simulation chambers down to 15 K, superconductivity between 1.8 K and up to 75 K (magnets, cavities or HTS devices like cables, FCL, SMES, etc), Cold Neutron Sources between 15 and 20 K, etc. Air Liquide Advanced Technologies is designing and manufacturing refrigerators since 60 years to satisfy those needs. The step by step developments achieved have led to machines with higher efficiency and reliability. In 1965, reciprocating compressors and Joule Thomson expansion valves weremore » used. In 1969, centripetal expanders began to be used. In 1980, oil lubricated screw compressors took the place of reciprocating compressors and a standard range of Claude cycle refrigerators was developed: the HELIAL series. 1980 was also the time for cryogenic centrifugal compressor development. In 2011, driven by the need for lower operational cost (high efficiency and low maintenance), cycle oil free centrifugal compressors on magnetic bearings were introduced instead of screw compressors. The power extracted by centripetal expanders was recovered. Based on this technology, a range of Turbo-Brayton refrigerators has been designed for temperatures between 40 K and 150 K. On-going development will enable widening the range of Turbo-Brayton refrigerators to cryogenic temperatures down to 15 K.. Cryogenic centrifugal circulators have been developed in order to answer to an increasing demand of 4 K refrigerators able to distribute cold power.« less

  15. War and hunting poisons of the New World. Part 1. Notes on the early history of curare.

    PubMed

    Bisset, N G

    1992-02-01

    The history to about 1850 of the muscle-relaxant poison curare is discussed, especially the developments leading to the botanical identification of the plants that yield the alkaloidal active principles: Loganiaceae (Strychnos species) and Menispermaceae (Abuta, Chondrodendron, and Curarea species). One of the earliest encounters with the poison appears to have been during the exploration of the Lake Maracaibo region in Colombia by Alonso Pérez de Tolosa in 1548. It is pointed out (yet again) that Sir Walter Ralegh did not bring back the poison to Europe in 1595 and that it was Keymis who first came across the word ourari when exploring the lower reaches of the Orinoco in 1596. Gumilla, La Condamine, Ulloa, Veigl, and others gave much additional information about the poison during the 18th century. Scientific studies began in the latter part of the century when Schreber listed the botanical identities of four of the plant components entering into the curare prepared by the Akawai Indians of Surinam. As far as is known, none of these people actually saw curare being made. Thereafter, progress was rapid. Humboldt and Bonpland were the first trained scientists to witness the preparation of the poison, at the very beginning of the 19th century. Subsequent exploration by Martius and Spix, Poeppig, Youd, the Schomburgk brothers, De Castelnau and Deville, Spruce, and others, up to the middle of the century, extended and deepened botanical and ethnological knowledge of curare. Study of its physiology started at about that time with the classical experiments of Rudolf von Koelliker and Claude Bernard.

  16. The infundibulo-tuberal syndrome caused by craniopharyngiomas: clinicopathological evidence from an historical French cohort (1705-1973).

    PubMed

    Castro-Dufourny, Inés; Carrasco, Rodrigo; Prieto, Ruth; Barrios, Laura; Pascual, José M

    2015-10-01

    Infundibulo-tuberal syndrome groups endocrine, metabolic and behavioral disturbances caused by lesions involving the upper neurohypophysis (median eminence) and adjacent basal hypothalamus (tuber cinereum). It was originally described by Henri Claude and Jean Lhermitte in 1917, in a patient with a craniopharyngioma. This study investigates the clinical, pathological and surgical evidence verifying the infundibulo-tuberal syndrome caused by craniopharyngiomas (CPs). A systematic retrospective review of craniopharyngiomas reported in French literature between 1705 and 1973 was conducted. A total of 128 well described reports providing a comprehensive clinical and pathological description of the tumors were selected. This series represents the historical French cohort of CPs reported in the pre-CT/MRI era. Three major syndromes caused by CPs were categorized: pituitary syndrome (35%), infundibulo-tuberal syndrome (52%) and hypothalamic syndrome (49%). CP topography was significantly related to the type of syndrome described (p < 0.001). Infundibulo-tuberal syndrome occurred in CPs which replaced or invaded the third ventricle floor. In contrast, the majority of sellar/suprasellar CPs growing below the third ventricle showed a pituitary syndrome (82%). Cases with hypothalamic syndrome were characterized by anatomical integrity of the pituitary gland and stalk (p = 0.033) and occurred predominantly in adults older than 41 years old (p < 0.005). Among infundibulo-tuberal symptoms, abnormal somnolence was not related with the presence of hydrocephalus. All squamous-papillary CPs presented psychiatric disturbances (p < 0.001). This historical CP cohort evidences a clinical-topographical correlation between the patient's type of syndrome and the anatomical structures involved by the tumor along the hypophysial-hypothalamic axis.

  17. Cato Guldberg and Peter Waage, the history of the Law of Mass Action, and its relevance to clinical pharmacology.

    PubMed

    Ferner, Robin E; Aronson, Jeffrey K

    2016-01-01

    We have traced the historical link between the Law of Mass Action and clinical pharmacology. The Law evolved from the work of the French chemist Claude Louis Berthollet, was first formulated by Cato Guldberg and Peter Waage in 1864 and later clarified by the Dutch chemist Jacobus van 't Hoff in 1877. It has profoundly influenced our qualitative and quantitative understanding of a number of physiological and pharmacological phenomena. According to the Law of Mass Action, the velocity of a chemical reaction depends on the concentrations of the reactants. At equilibrium the concentrations of the chemicals involved bear a constant relation to each other, described by the equilibrium constant, K. The Law of Mass Action is relevant to various physiological and pharmacological concepts, including concentration-effect curves, dose-response curves, and ligand-receptor binding curves, all of which are important in describing the pharmacological actions of medications, the Langmuir adsorption isotherm, which describes the binding of medications to proteins, activation curves for transmembrane ion transport, enzyme inhibition and the Henderson-Hasselbalch equation, which describes the relation between pH, as a measure of acidity and the concentrations of the contributory acids and bases. Guldberg and Waage recognized the importance of dynamic equilibrium, while others failed to do so. Their ideas, over 150 years old, are embedded in and still relevant to clinical pharmacology. Here we explain the ideas and in a subsequent paper show how they are relevant to understanding adverse drug reactions. © 2015 The British Pharmacological Society.

  18. Galileo and Music: A Family Affair

    NASA Astrophysics Data System (ADS)

    Fabris, D.

    2011-06-01

    According to Viviani, Galileo's first biographer, the scientist was an excellent keyboard and lute player. In turn Vincenzo Galilei, father of the illustrious scientist, had been one of the most influential music theorist of his age and also a great composer and virtuoso of the lute. Galileo and his brother Michelangelo, born in 1575, inherited Vincenzo's duel skills, both in theory and practical music: Galileo's correspondences show indeed his competence in the music and in the lute playing; Michelagnolo, after being educated in part in Galileo's house in Padua, transferred to Germany in Munich, where he became a court lute player. Nevertheless, Galileo helped for the rest of his life not only his brother but also his nephews, as documented in dozen of family letters quite important to establish the central role of the music in Galileo's everyday life, a fact almost ignored by most modern biographers. The importance of music in Galileo's output and life has been first outlined by the historian of sciences Stillman Drake and by the musicologist Claude Palisca. After their studies starting in the 1960s there is a great belief that Vincenzo influenced his son Galileo, directing him towards experimentation. The aim of this paper, following the reconstruction of Galileo's soundscape proposed by Pierluigi Petrobelli, is to reexamine the surviving historical accounts on the musical passion and talent of Galileo and his family in the several houses where they performed music (in Florence, Padua, Munich, etc.) in particular on the lute, the instrument that was an important experimental tool for the scientist.

  19. Computed tomographic findings in 205 dogs with clinical signs compatible with middle ear disease: a retrospective study.

    PubMed

    Belmudes, Audrey; Pressanti, Charline; Barthez, Paul Y; Castilla-Castaño, Eloy; Fabries, Lionel; Cadiergues, Marie C

    2018-02-01

    Computed tomography (CT) is considered to be the reference method to evaluate middle ear structures. To evaluate the presence and severity of CT changes in the middle ear and establish if any specific clinical presentations are associated with otitis media. Medical records of animals referred for CT with history and clinical signs consistent with middle ear disease. Retrospective evaluation of CT examinations of tympanic bullae performed over a six year period. Medical records were reviewed for signalment, clinical signs and cytological evaluation of the external ear canal. Dogs were divided into three clinical groups: chronic otitis externa (Group 1), peripheral vestibular disorder (Group 2) and other clinical presentations (Group 3). Group 1 - Of 214 ears, 87 (40.7%) had CT abnormalities: 38 of 87 (17.7%) had material-filled bullae, 42 of 87 (19.6%) had thickened bullae walls and seven of 87 (3.2%) had lysis of the bulla. Abnormalities were significantly more frequent in dogs with suppurative otitis than in erythemato-ceruminous otitis (57% and 23%, respectively; P = 0.003). Proliferative otitis, particularly in French bulldogs, was associated with severe otitis media. Group 2 - Of the 106 ears, 91 (85.8%) had normal tympanic bullae. Group 3 - Of the 26 ears from deaf dogs, 17 had filled bullae; all nine affected dogs were Cavalier King Charles spaniels. All dogs with Claude Bernard Horner syndrome or head tilt had normal tympanic bullae. CT is useful for canine chronic otitis externa, particularly in suppurative or proliferative otitis, even in the absence of associated neurological signs. © 2017 ESVD and ACVD.

  20. [Homage to Doctor Theodore Vetter (1916-2004). President of the French Society of the History of Medicine from 1976 to 1978].

    PubMed

    Le Minor, Jean-Marie

    2007-01-01

    Théodore Vetter (Strasbourg, 1916, June 19th - 2004, July 8th) was qualified as a medical doctor in medicine in 1948 in Strasbourg, and then followed complementary courses in medical biology in Paris. He realized most of his career as an adviser for medical research in pharmaceutical industry. He presented an early talent for drawing and graphic arts, encouraged by Georges Ritleng (1875-1972), headmaster of the School of decorative arts in Strasbourg. One expression of the artistic gift of Th. Vetter consisted in design and making of ex-libris, field in which he acquired an international reputation. In total, he realized about two hundred ex-libris, mostly for physicians. Also attracted by the history of medicine, he became a member of the Société Française d'Histoire de la Médecine; he was general secretary from 1965 to 1970, then he became vice-president and president from 1976 to 1978. He was the author of about a hundred works concerning the history of medicine; all were characterized by a great rigour and by the direct use of original sources. Among his main works, his studies on the oculist Jacques Daviel (1693-1762), popularizer of the surgery of cataract, on the surgeon Claude Nicolas Le Cat (1700-1768), on the birth of pathology, a commented edition of the complete works of Hippocrates, translated by M.P.E. Littré (1801-1881), and numerous papers on the history of medicine in Strasbourg and Alsace.

  1. STS-103 crew take part in CEIT in the orbiter Discovery

    NASA Technical Reports Server (NTRS)

    1999-01-01

    In the payload bay of the orbiter Discovery, STS-103 Mission Specialists John M. Grunsfeld (Ph.D.), left, and Claude Nicollier of Switzerland, right, are briefed on part of the equipment they will use on their mission by a worker from Johnson Space Center, center. The mission involves the repair and upgrade of the Hubble Space Telescope. The crew, who are at KSC to take part in a Crew Equipment Interface Test, also includes Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), and Jean-Fran'''ois Clervoy of France. Nicollier and Clervoy are with the European Space Agency. Mission STS-103 is a 'call-up' due to the need to replace portions of the pointing system, the gyros, which have begun to fail on the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. The gyroscopes allow the telescope to point at stars, galaxies and planets. The STS- 103 crew will not only replace gyroscopes, it will also replace a Fine Guidance Sensor and an older computer with a new enhanced model, an older data tape recorder with a solid-state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. The scheduled launch date in October is under review.

  2. STS-103 crew take part in CEIT in OPF 1

    NASA Technical Reports Server (NTRS)

    1999-01-01

    In the Orbiter Processing Facility (OPF) bay 1, STS-103 crew members look over equipment to be used on planned Extravehicular Activities (EVAs) on the mission for repair of the Hubble Space Telescope. They are taking part in a Crew Equipment Interface Test (CEIT) at KSC. From left are Mission Specialists C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.) Claude Nicollier of Switzerland, and Steven L. Smith. Other crew members at KSC for the CEIT are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, and Jean-Frangois Clervoy of France. Nicollier and Clervoy are with the European Space Agency. Mission STS-103 is a 'call-up' due to the need to replace portions of the pointing system, the gyros, which have begun to fail on the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. The gyroscopes allow the telescope to point at stars, galaxies and planets. The STS-103 crew will not only replace gyroscopes, it will also replace a Fine Guidance Sensor and an older computer with a new enhanced model, an older data tape recorder with a solid-state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. The scheduled launch date in October is under review.

  3. Chandra Discovers the X-ray Signature of a Powerful Wind from a Galactic Microquasar

    NASA Astrophysics Data System (ADS)

    2000-11-01

    NASA's Chandra X-ray Observatory has detected, for the first time in X rays, a stellar fingerprint known as a P Cygni profile--the distinctive spectral signature of a powerful wind produced by an object in space. The discovery reveals a 4.5-million-mile-per-hour wind coming from a highly compact pair of stars in our galaxy, report researchers from Penn State and the Massachusetts Institute of Technology in a paper they will present on 8 November 2000 during a meeting of the High-Energy Astrophysics Division of the American Astronomical Society in Honolulu, Hawaii. The paper also has been accepted for publication in The Astrophysical Journal Letters. "To our knowledge, these are the first P Cygni profiles reported in X rays," say researchers Niel Brandt, assistant professor of astronomy and astrophysics at Penn State, and Norbert S. Schulz, research scientist at the Massachusetts Institute of Technology. The team made the discovery during their first observation of a binary-star system with the Chandra X-ray Observatory, which was launched into space in July 1999. The system, known as Circinus X-1, is located about 20,000 light years from Earth in the constellation Circinus near the Southern Cross. It contains a super-dense neutron star in orbit around a normal fusion-burning star like our Sun. Although Circinus X-1 was discovered in 1971, many properties of this system remain mysterious because Circinus X-1 lies in the galactic plane where obscuring dust and gas have blocked its effective study in many wavelengths. The P Cygni spectral profile, previously detected primarily at ultraviolet and optical wavelengths but never before in X rays, is the textbook tool astronomers rely on for probing stellar winds. The profile looks like the outline of a roller coaster, with one really big hill and valley in the middle, on a data plot with velocity on one axis and the flow rate of photons per second on the other. It is named after the famous star P Cygni, in which such

  4. STS-103 crew look over payload inside Discovery

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Members of the STS-103 crew, with representatives from Goddard Space Flight Center, look over the Hubble servicing cargo in the payload bay of Space Shuttle Discovery at Launch Pad 39B. From left are Mission Specialist Steven L. Smith and Claude Nicollier of Switzerland; Steve Pataki and Dave Southwick, with Goddard; and Mission Commander Curtis L. Brown Jr. Inspecting the payload is part of the Terminal Countdown Demonstration Test (TCDT), which also provides the crew with emergency egress training and a simulated countdown exercise. Other crew members taking part in the TCDT are Pilot Scott J. Kelly, and Mission Specialists C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), and Jean- Fran'''ois Clervoy of France. Clervoy and Nicollier are with the European Space Agency. STS-103 is a 'call-up' mission due to the need to replace and repair portions of the Hubble Space Telescope, including the gyroscopes that allow the telescope to point at stars, galaxies and planets. The STS-103 crew will be replacing a Fine Guidance Sensor, an older computer with a new enhanced model, an older data tape recorder with a solid-state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The mission is targeted for launch Dec. 6 at 2:37 a.m. EST.

  5. KSC-99padig036

    NASA Image and Video Library

    1999-11-13

    KENNEDY SPACE CENTER, FLA. -- Towering atop the mobile launcher platform and crawler transporter, Space Shuttle Discovery negotiates a turn in the crawlerway on its trek from the Vehicle Assembly Building to Launch Pad 39B. While at the pad, the orbiter, external tank and solid rocket boosters will undergo final preparations for the STS-103 launch targeted for Dec. 6, 1999, at 2:37 a.m. EST. The mission is a "call-up" due to the need to replace portions of the pointing system the gyros which have begun to fail on the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. The gyroscopes allow the telescope to point at stars, galaxies and planets. The STS-103 crew will also be installing a Fine Guidance Sensor, a new enhanced computer, a solid-state digital recorder, and a new spare transmitter to replace older equipment, and replacing degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The STS-103 crew members are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, Mission Specialist Steven L. Smith, Mission Specialist C. Michael Foale (Ph.D.), Mission Specialist John M. Grunsfeld (Ph.D.), and Mission Specialist Claude Nicollier of Switzerland, and Mission Specialist Jean-François Clervoy of France, both with the European Space Agency

  6. KSC-99padig035

    NASA Image and Video Library

    1999-11-13

    KENNEDY SPACE CENTER, FLA. -- Under low clouds and fog, Space Shuttle Discovery makes its trek along the stretch of crawlerway between the Vehicle Assembly Building and Launch Pad 39B atop the mobile launcher platform and crawler transporter. Once at the pad, the orbiter, external tank and solid rocket boosters will undergo final preparations for the STS-103 launch targeted for Dec. 6, 1999, at 2:37 a.m. EST. The mission is a "call-up" due to the need to replace portions of the pointing system the gyros which have begun to fail on the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. The gyroscopes allow the telescope to point at stars, galaxies and planets. The STS-103 crew will also be installing a Fine Guidance Sensor, a new enhanced computer, a solid-state digital recorder, and a new spare transmitter to replace older equipment, and replacing degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The STS-103 crew members are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, Mission Specialist Steven L. Smith, Mission Specialist C. Michael Foale (Ph.D.), Mission Specialist John M. Grunsfeld (Ph.D.), and Mission Specialist Claude Nicollier of Switzerland, and Mission Specialist Jean-François Clervoy of France, both with the European Space Agency

  7. KSC-99padig033

    NASA Image and Video Library

    1999-11-13

    KENNEDY SPACE CENTER, FLA. -- Under low clouds and fog, Space Shuttle Discovery makes its trek along the stretch of crawlerway between the Vehicle Assembly Building and Launch Pad 39B atop the mobile launcher platform and crawler transporter. Once at the pad, the orbiter, external tank and solid rocket boosters will undergo final preparations for the STS-103 launch targeted for Dec. 6, 1999, at 2:37 a.m. EST. The mission is a "call-up" due to the need to replace portions of the pointing system the gyros which have begun to fail on the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. The gyroscopes allow the telescope to point at stars, galaxies and planets. The STS-103 crew will also be installing a Fine Guidance Sensor, a new enhanced computer, a solid-state digital recorder, and a new spare transmitter to replace older equipment, and replacing degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The STS-103 crew members are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, Mission Specialist Steven L. Smith, Mission Specialist C. Michael Foale (Ph.D.), Mission Specialist John M. Grunsfeld (Ph.D.), and Mission Specialist Claude Nicollier of Switzerland, and Mission Specialist Jean-François Clervoy of France, both with the European Space Agency.

  8. STS-103 MS Clervoy and Pilot Kelly inspect slideware basket at Pad 39B

    NASA Technical Reports Server (NTRS)

    1999-01-01

    At Launch Pad 39B. STS-103 Mission Specialist Jean-Frangois Clervoy of France, who is with the European Space Agency (ESA), and Pilot Steven J. Kelly inspect the slidewire basket, part of the emergency egress system for persons in the Shuttle vehicle or on the Rotating Service Structure. Seven slidewires extend from the orbiter access arm, with a netted, flatbottom basket suspended from each wire. The STS-103 crew have been participating in Terminal Countdown Demonstration Test (TCDT) activities at KSC. Other crew members are Commander Curtis L. Brown Jr. and Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), and Claude Nicollier of Switzerland, also with ESA. The TCDT provides the crew with the emergency egress training, opportunities to inspect their mission payloads in the orbiter's payload bay, and simulated countdown exercises. STS-103 is a 'call-up' mission due to the need to replace and repair portions of the Hubble Space Telescope, including the gyroscopes that allow the telescope to point at stars, galaxies and planets. The STS-103 crew will be replacing a Fine Guidance Sensor, an older computer with a new enhanced model, an older data tape recorder with a solid-state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The mission is targeted for launch Dec. 6 at 2:37 a.m. EST.

  9. STS-103 crew practice emergency egress in the slidewire basket

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Standing left to right, STS-103 Pilot Scott J. Kelly, Commander Curtis L. Brown Jr., and Mission Specialist Jean-Frangois Clervoy of France take a break during practice using the slidewire baskets, part of Terminal Countdown Demonstration Test (TCDT) activities in preparation for launch. The other crew members taking part are Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), and Claude Nicollier of Switzerland. Clervoy and Nicollier are with the European Space Agency. The baskets are part of the emergency egress system for persons in the Shuttle vehicle or on the Rotating Service Structure. Seven slidewires extend from the orbiter access arm, with a netted, flatbottom basket suspended from each wire. The TCDT also provides the crew with opportunities to inspect their mission payloads in the orbiter's payload bay, and simulated countdown exercises. STS-103 is a 'call-up' mission due to the need to replace and repair portions of the Hubble Space Telescope, including the gyroscopes that allow the telescope to point at stars, galaxies and planets. The STS-103 crew will be replacing a Fine Guidance Sensor, an older computer with a new enhanced model, an older data tape recorder with a solid-state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The mission is targeted for launch Dec. 6 at 2:37 a.m. EST.

  10. French roots of French neo-lamarckisms, 1879-1985.

    PubMed

    Loison, Laurent

    2011-01-01

    This essay attempts to describe the neo-Lamarckian atmosphere that was dominant in French biology for more than a century. Firstly, we demonstrate that there were not one but at least two French neo-Lamarckian traditions. This implies, therefore, that it is possible to propose a clear definition of a (neo)Lamarckian conception, and by using it, to distinguish these two traditions. We will see that these two conceptions were not dominant at the same time. The first French neo-Lamarckism (1879-1931) was structured by a very mechanic view of natural processes. The main representatives of this first period were scientists such as Alfred Giard (1846-1908), Gaston Bonnier (1853-1922) and Félix Le Dantec (1869-1917). The second Lamarckism - much more vitalist in its inspiration - started to develop under the supervision of people such as Albert Vandel (1894-1980) and Pierre-Paul Grassé (1895-1985). Secondly, this essay suggests that the philosophical inclinations of these neo-Lamarckisms reactivated a very ancient and strong dichotomy of French thought. One part of this dichotomy is a material, physicalist tradition, which started with René Descartes but developed extensively during the 18th and 19th centuries. The other is a spiritual and vitalist reaction to the first one, which also had a very long history, though it is most closely associated with the work of Henri Bergson. Through Claude Bernard, the first neo-Lamarckians tried to construct a mechanical and determinist form of evolutionary theory which was, in effect, a Cartesian theory. The second wave of neo-Lamarckians wanted to reconsider the autonomy and reactivity of life forms, in contrast to purely physical systems.

  11. [Alternatives to animal experimentation v.s. animal rights terrorism].

    PubMed

    Kurosawa, Tsutomu Miki

    2008-05-01

    Systematic modern animal experimentation was established by Bernard Claude who wrote "An Introduction to the Study of Experimental Medicine" in 1865. At this point, the public was already asking that the pain and distress of experimental animals be reduced. For this, scientists, William Russell and Rex Burch in 1959 proposed the principles of alternatives to animal experimentation, the "3Rs". Since that time, animal welfare advocates have promoted the 3Rs concept in biomedical research communities. However, cruel animal experiments have continued and there are reports of radical extremists showing their opposition by invasion, arson, theft and even bombing of institutions involved, resulting in killing of the animals. SHAC, one extremist group believed to be animal welfare activitists was recognized as a terrorist group after the 9.11 tragedy in USA and the government viewed their activities very seriously. In 2001, British animal extremists invaded Japanese universities and stole laboratory resources; one individual was arrested and sentenced to prison for three years; Japanese who assisted in the incident were arrested and one was sentenced for one year. In 2006, SHAC USA members were prosecuted and sentenced for up to 6 years for their terrorism activities including arson. We need to consider the background of these activities which are financially supported by animal welfare advocates. The way we, as scientists who conduct such experiments can respond is by promoting alternatives to this experimentation. In Japan, the animal welfare law was revised in 2005 stressing the importance of 3Rs in scientific activities with animals. The promotion of 3Rs should be strengthened in the pharmaceutical community.

  12. 3D seismic imaging of an active, normal fault zone in southern Apennines (Italy): Clues on fluid-driven microearthquake fracturing

    NASA Astrophysics Data System (ADS)

    Amoroso, O.; Zollo, A.; Virieux, J.

    2012-12-01

    We have reconstructed a 3D detailed image of the crustal volume embedding the active normal fault system in southern Apennines (Italy). It is obtained by the inversion of P and S first arrival times from microearthquakes recorded in the area. The issues of data quality and the implementation of robust tomographic inversion strategy have been addressed to improve the resolution of the seismic image. The arrival times measurements are enhanced by applying techniques based on polarization filtering and refined re-picking. Data inversion has been performed by using a delay-time 3D tomographic method for the joint determination of source locations and velocity model. The dataset consists of 1311 events with magnitude ranging between [0.1, 3.2], recorded from August 2005 to April 2011 by 42 stations operated by the consortium AMRA scarl and INGV. We used a multi-scale inversion approach, in order to first estimate the large wavelength components of the velocity model and then to progressively introduce smaller scale components. P- and S-wave velocity models show a strong lateral variation along a direction orthogonal to the Apeninic chain, between 0-15 km depth. This variation defines two geological formations which are characterized by relatively low and high P-wave velocities. The sharpest lateral transition occurs in the NE direction: it is well correlated with the location of the NW-SE oriented, primary normal fault associated with the 1980, Ms 6.9 earthquake, which cuts at SW the outcrops of the carbonatic Campanian platform, and separates at NE the older Mesozoic limestone formations from the younger Pliocene-Quaternary basin deposits. The main lithological formations, as identified in the referenced active seismic CROP04 profile, can be recognized in the inferred velocity model. In particular, the structural feature associated with the uplift of the Apulian Platform is well detected by the high P-velocity anomaly ranging between 6.0-6.8 km/s. The thickening of the

  13. Vitalism and the resistance to experimentation on life in the eighteenth century.

    PubMed

    Wolfe, Charles T

    2013-01-01

    There is a familiar opposition between a 'Scientific Revolution' ethos and practice of experimentation, including experimentation on life, and a 'vitalist' reaction to this outlook. The former is often allied with different forms of mechanism - if all of Nature obeys mechanical laws, including living bodies, 'iatromechanism' should encounter no obstructions in investigating the particularities of animal-machines - or with more chimiatric theories of life and matter, as in the 'Oxford Physiologists'. The latter reaction also comes in different, perhaps irreducibly heterogeneous forms, ranging from metaphysical and ethical objections to the destruction of life, as in Margaret Cavendish, to more epistemological objections against the usage of instruments, the 'anatomical' outlook and experimentation, e.g. in Locke and Sydenham. But I will mainly focus on a third anti-interventionist argument, which I call 'vitalist' since it is often articulated in the writings of the so-called Montpellier Vitalists, including their medical articles for the Encyclopédie. The vitalist argument against experimentation on life is subtly different from the metaphysical, ethical and epistemological arguments, although at times it may borrow from any of them. It expresses a Hippocratic sensibility - understood as an artifact of early modernity, not as some atemporal trait of medical thought - in which Life resists the experimenter, or conversely, for the experimenter to grasp something about Life, it will have to be without torturing or radically intervening in it. I suggest that this view does not have to imply that Nature is something mysterious or sacred; nor does the vitalist have to attack experimentation on life in the name of some 'vital force' - which makes it less surprising to find a vivisectionist like Claude Bernard sounding so close to the vitalists.

  14. A multi-disciplinary approach to the origins of music: perspectives from anthropology, archaeology, cognition and behaviour.

    PubMed

    Morley, Iain

    2014-01-01

    Archaeological evidence for musical activities pre-dates even the earliest-known cave art and it remains the case that no human culture has yet been encountered that does not practise some recognisably musical activity. Yet the human abilities to make and appreciate music have been described as "amongst the most mysterious with which [we are] endowed" (Charles Darwin, 1872) and music itself as "the supreme mystery of the science of man" (Claude Levi-Strauss, 1970). Like language, music has been the subject of keen investigation across a great diversity of fields, from neuroscience and psychology, to ethnography, to studies of its structures in its own dedicated field, musicology; unlike the evolution of human language abilities, it is only recently that the origins of musical capacities have begun to receive dedicated attention. It is increasingly clear that human musical abilities are fundamentally related to other important human abilities, yet much remains mysterious about this ubiquitous human phenomenon, not least its prehistoric origins. It is evident that no single field of investigation can address the wide range of issues relevant to answering the question of music's origins. This review brings together evidence from a wide range of anthropological and human sciences, including palaeoanthropology, archaeology, neuroscience, primatology and developmental psychology, in an attempt to elucidate the nature of the foundations of music, how they have evolved, and how they are related to capabilities underlying other important human behaviours. It is proposed that at their most fundamental level musical behaviours (including both vocalisation and dance) are forms of deliberate metrically-organised gesture, and constitute a specialised use of systems dedicated to the expression and comprehension of social and emotional information between individuals. The abilities underlying these behaviours are selectively advantageous themselves; in addition, various mechanisms

  15. The calcium feedback loop and T cell activation: how cytoskeleton networks control intracellular calcium flux.

    PubMed

    Joseph, Noah; Reicher, Barak; Barda-Saad, Mira

    2014-02-01

    . Guest Editor: Jean Claude Hervé. © 2013.

  16. Research Priorities to Advance the Health and Health Care of Older Adults with Multiple Chronic Conditions.

    PubMed

    Tisminetzky, Mayra; Bayliss, Elizabeth A; Magaziner, Jay S; Allore, Heather G; Anzuoni, Kathryn; Boyd, Cynthia M; Gill, Thomas M; Go, Alan S; Greenspan, Susan L; Hanson, Leah R; Hornbrook, Mark C; Kitzman, Dalane W; Larson, Eric B; Naylor, Mary D; Shirley, Benjamin E; Tai-Seale, Ming; Teri, Linda; Tinetti, Mary E; Whitson, Heather E; Gurwitz, Jerry H

    2017-07-01

    To prioritize research topics relevant to the care of the growing population of older adults with multiple chronic conditions (MCCs). Survey of experts in MCC practice, research, and policy. Topics were derived from white papers, funding announcements, or funded research projects relating to older adults with MCCs. Survey conducted through the Health Care Systems Research Network (HCSRN) and Claude D. Pepper Older Americans Independence Centers (OAICs) Advancing Geriatrics Infrastructure and Network Growth Initiative, a joint endeavor of the HCSRN and OAICs. Individuals affiliated with the HCSRN or OAICs and national MCC experts, including individuals affiliated with funding agencies having MCC-related grant portfolios. A "top box" methodology was used, counting the number of respondents selecting the top response on a 5-point Likert scale and dividing by the total number of responses to calculate a top box percentage for each of 37 topics. The highest-ranked research topics relevant to the health and healthcare of older adults with MCCs were health-related quality of life in older adults with MCCs; development of assessment tools (to assess, e.g., symptom burden, quality of life, function); interactions between medications, disease processes, and health outcomes; disability; implementation of novel (and scalable) models of care; association between clusters of chronic conditions and clinical, financial, and social outcomes; role of caregivers; symptom burden; shared decision-making to enhance care planning; and tools to improve clinical decision-making. Study findings serve to inform the development of a comprehensive research agenda to address the challenges relating to the care of this "high-need, high-cost" population and the healthcare delivery systems responsible for serving it. © 2017, Copyright the Authors Journal compilation © 2017, The American Geriatrics Society.

  17. The short history of gastroenterology.

    PubMed

    Sródka, A

    2003-12-01

    In this paper research on the stomach and bowel physiology is presented in a historical perspective. The author tries to show how digestive processes were interpreted by the ancients and how they tried to adjust them to the dominating humoral theory of disease. It is pointed out that the breakthrough which created a new way of understanding of the function of the digestive system was made by Andreas Vesalius and his modern model of anatomy. The meaning of acceptance of chemical processes in digestion by iatrochemics representatives in XVII century is shown. Physiological research in XIX century, which decided about a rapid development of physiology, especially the physiology of the gastrointestinal tract, is discussed. Experiments were performed by all main representatives of this discipline: Claude Bernard, Jan Ewangelista Purkyne, Rudolph Heidenhain and especially Ivan Pavlov, who, thanks to the discoveries in the secretion physiology, explained basic functions of the central nervous system. The XX century was dominated by the research showing the important role of the endocrine system and biological agents in the regulation of secretion and motility of the digestive system. The following discoveries are discussed: Ernest Sterling (secretin), John Edkins (gastrin) and André Latarjet and Lester Dragstedt (acetylcholine). It is underlined that Polish scientists play an important role in the development of the gastroenterological science--among others, Walery Jaworski, who made a historical suggestion about the role of the spiral bacteria in etiopathogenesis of the peptic ulcer, Leon Popielski, who stated the stimulating influence of histamine on the stomach acid secretion, Julian Walawski, who discovered enterogastrons--hormones decreasing secretion. As a supplement, there is the list of achievements in the field of the physiology and pathology of the gastrointestinal tract awarded with Nobel Prize and the list of most important Polish papers in this field.

  18. STS-103 crew practice emergency egress in the slidewire basket

    NASA Technical Reports Server (NTRS)

    1999-01-01

    In the slidewire basket on Launch Pad 39B, STS-103 Mission Specialists Jean-Frangois Clervoy of France (left) and Steven L. Smith take a break to pose for the photographer. The baskets are part of the emergency egress system for persons in the Shuttle vehicle or on the Rotating Service Structure. Seven slidewires extend from the orbiter access arm, with a netted, flatbottom basket suspended from each wire. The STS-103 crew are taking part in Terminal Countdown Demonstration Test (TCDT) activities in preparation for launch. The other crew members are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, and Mission Specialists C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), and Claude Nicollier of Switzerland. Clervoy and Nicollier are with the European Space Agency. The TCDT provides the crew with the emergency egress training, opportunities to inspect their mission payloads in the orbiter's payload bay, and simulated countdown exercises. STS-103 is a 'call-up' mission due to the need to replace and repair portions of the Hubble Space Telescope, including the gyroscopes that allow the telescope to point at stars, galaxies and planets. The STS-103 crew will be replacing a Fine Guidance Sensor, an older computer with a new enhanced model, an older data tape recorder with a solid-state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The mission is targeted for launch Dec. 6 at 2:37 a.m. EST.

  19. STS-103 crew practice emergency egress in the slidewire basket

    NASA Technical Reports Server (NTRS)

    1999-01-01

    In the slidewire basket on Launch Pad 39B, STS-103 Mission Specialist Steven L. Smith reaches for the lever that will release the basket. With Smith is fellow crew member Mission Specialist Jean-Frangois Clervoy of France. The baskets are part of the emergency egress system for persons in the Shuttle vehicle or on the Rotating Service Structure. Seven slidewires extend from the orbiter access arm, with a netted, flatbottom basket suspended from each wire. The STS-103 crew are taking part in Terminal Countdown Demonstration Test (TCDT) activities in preparation for launch. The other crew members are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, and Mission Specialists C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), and Claude Nicollier of Switzerland. Clervoy and Nicollier are with the European Space Agency. The TCDT provides the crew with the emergency egress training, opportunities to inspect their mission payloads in the orbiter's payload bay, and simulated countdown exercises. STS-103 is a 'call-up' mission due to the need to replace and repair portions of the Hubble Space Telescope, including the gyroscopes that allow the telescope to point at stars, galaxies and planets. The STS-103 crew will be replacing a Fine Guidance Sensor, an older computer with a new enhanced model, an older data tape recorder with a solid-state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The mission is targeted for launch Dec. 6 at 2:37 a.m. EST.

  20. STS-103 crew practice emergency egress in the slidewire basket

    NASA Technical Reports Server (NTRS)

    1999-01-01

    In the slidewire basket on Launch Pad 39B, STS-103 Commander Curtis L. Brown Jr. (left) and Pilot Scott J. Kelly (right) adjust their equipment. The baskets are part of the emergency egress system for persons in the Shuttle vehicle or on the Rotating Service Structure. Seven slidewires extend from the orbiter access arm, with a netted, flatbottom basket suspended from each wire. The other crew members are Mission Specialists Steven L. Smith, C. Michael Foale (Ph.D.), John M. Grunsfeld (Ph.D.), Claude Nicollier of Switzerland, with the European Space Agency (ESA), and Jean-Frangois Clervoy of France, also with ESA.. The STS-103 crew are taking part in Terminal Countdown Demonstration Test (TCDT) activities in preparation for launch. The TCDT provides the crew with the emergency egress training, opportunities to inspect their mission payloads in the orbiter's payload bay, and simulated countdown exercises. STS-103 is a 'call-up' mission due to the need to replace and repair portions of the Hubble Space Telescope, including the gyroscopes that allow the telescope to point at stars, galaxies and planets. The STS-103 crew will be replacing a Fine Guidance Sensor, an older computer with a new enhanced model, an older data tape recorder with a solid-state digital recorder, a failed spare transmitter with a new one, and degraded insulation on the telescope with new thermal insulation. The crew will also install a Battery Voltage/Temperature Improvement Kit to protect the spacecraft batteries from overcharging and overheating when the telescope goes into a safe mode. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The mission is targeted for launch Dec. 6 at 2:37 a.m. EST.