Sample records for clear linear relationship

  1. Characterizing driver-response relationships in marine pelagic ecosystems for improved ocean management.

    PubMed

    Hunsicker, Mary E; Kappel, Carrie V; Selkoe, Kimberly A; Halpern, Benjamin S; Scarborough, Courtney; Mease, Lindley; Amrhein, Alisan

    2016-04-01

    Scientists and resource managers often use methods and tools that assume ecosystem components respond linearly to environmental drivers and human stressors. However, a growing body of literature demonstrates that many relationships are-non-linear, where small changes in a driver prompt a disproportionately large ecological response. We aim to provide a comprehensive assessment of the relationships between drivers and ecosystem components to identify where and when non-linearities are likely to occur. We focused our analyses on one of the best-studied marine systems, pelagic ecosystems, which allowed us to apply robust statistical techniques on a large pool of previously published studies. In this synthesis, we (1) conduct a wide literature review on single driver-response relationships in pelagic systems, (2) use statistical models to identify the degree of non-linearity in these relationships, and (3) assess whether general patterns exist in the strengths and shapes of non-linear relationships across drivers. Overall we found that non-linearities are common in pelagic ecosystems, comprising at least 52% of all driver-response relation- ships. This is likely an underestimate, as papers with higher quality data and analytical approaches reported non-linear relationships at a higher frequency (on average 11% more). Consequently, in the absence of evidence for a linear relationship, it is safer to assume a relationship is non-linear. Strong non-linearities can lead to greater ecological and socioeconomic consequences if they are unknown (and/or unanticipated), but if known they may provide clear thresholds to inform management targets. In pelagic systems, strongly non-linear relationships are often driven by climate and trophodynamic variables but are also associated with local stressors, such as overfishing and pollution, that can be more easily controlled by managers. Even when marine resource managers cannot influence ecosystem change, they can use information about threshold responses to guide how other stressors are managed and to adapt to new ocean conditions. As methods to detect and reduce uncertainty around threshold values improve, managers will be able to better understand and account for ubiquitous non-linear relationships.

  2. Smoking, Exercise, and Physical Fitness

    DTIC Science & Technology

    1990-11-30

    mile runi and muscular (sit-ups), as well as lean body mass showed clear linear relationships with caloric expenditure resultini from exercise...continuous walking, swimming, bicyling, playing racket sports, aerobic dancing ,/exercising, weight lifting, performing calisthenics, and playing basketball

  3. The Radial Variation of the Solar Wind Temperature-Speed Relationship

    NASA Astrophysics Data System (ADS)

    Elliott, H. A.; McComas, D. J.

    2010-12-01

    Generally, the solar wind temperature (T) and speed (V) are well correlated except in Interplanetary Coronal Mass Ejections where this correlation breaks down. We have shown that at 1 AU the speed-temperature relationship is often well represented by a linear fit for a speed range spanning both the slow and fast wind. By examining all of the ACE and OMNI measurements, we found that when coronal holes are large the fast wind can have a different T-V relationship than the slow wind. The best example of this was in 2003 when there was a very large and long-lived outward polarity coronal hole at low latitudes. The long-lived nature of the hole made it possible to clearly distinguish that large holes can have a different T-V relationship. We found it to be rare that holes are large enough and last long enough to have enough data points to clearly demonstrate this effect. In this study we compare the 2003 coronal hole observations from ACE with the Ulysses polar coronal hole measurements. In an even earlier ACE study we found that both the compressions and rarefactions curves are linear, but the compression curve is shifted to higher temperatures. In this presentation we use Helios, Ulysses, and ACE measurements to examine how the T-V relationship varies with distance. The dynamic evolution of the solar wind parameters is revealed when we first separate compressions and rarefactions and then determine the radial profiles of the solar wind parameters. We find that T-V relationship varies with distance and in particular beyond 3 AU the differences between the compressions and rarefactions are quite important and at such distances a simple linear fit does not represent the T-V distribution very well.

  4. The Non-Linear Relationship between BMI and Health Care Costs and the Resulting Cost Fraction Attributable to Obesity.

    PubMed

    Laxy, Michael; Stark, Renée; Peters, Annette; Hauner, Hans; Holle, Rolf; Teuner, Christina M

    2017-08-30

    This study aims to analyse the non-linear relationship between Body Mass Index (BMI) and direct health care costs, and to quantify the resulting cost fraction attributable to obesity in Germany. Five cross-sectional surveys of cohort studies in southern Germany were pooled, resulting in data of 6757 individuals (31-96 years old). Self-reported information on health care utilisation was used to estimate direct health care costs for the year 2011. The relationship between measured BMI and annual costs was analysed using generalised additive models, and the cost fraction attributable to obesity was calculated. We found a non-linear association of BMI and health care costs with a continuously increasing slope for increasing BMI without any clear threshold. Under the consideration of the non-linear BMI-cost relationship, a shift in the BMI distribution so that the BMI of each individual is lowered by one point is associated with a 2.1% reduction of mean direct costs in the population. If obesity was eliminated, and the BMI of all obese individuals were lowered to 29.9 kg/m², this would reduce the mean direct costs by 4.0% in the population. Results show a non-linear relationship between BMI and health care costs, with very high costs for a few individuals with high BMI. This indicates that population-based interventions in combination with selective measures for very obese individuals might be the preferred strategy.

  5. Relationships between depression, anxiety, and pain in a group of university music students.

    PubMed

    Wristen, Brenda W; Fountain, Sarah E

    2013-09-01

    There is emerging interest in studying the incidence of music-related injuries and problems among students. The current study drew on a data set collected from 287 music majors and minors at a large US midwestern university school of music in order to determine if correlations existed between anxiety and/or depression and the reported presence of physical pain, and to understand the nature of any such relationships. Physical pain symptoms were scored on a scale of 0 (none) to 10 (excruciating) and summed across 21 body regions. Depression and anxiety symptoms were scored as none (0), mild (1), moderate (2), or severe (3), and each summed across either 13 symptoms for depression or 8 symptoms for anxiety. The potential linear relationship among these variables was evaluated using F-tests (as part of ANOVAs) and linear regression parameter estimation techniques. The explanatory value of these relationships was evaluated using R² values. Results indicate a clear positive linear relationship between both depression and pain, and anxiety and pain. However, the presence of depression and/or anxiety symptoms was insufficient to explain variability in pain scores of these participants.

  6. Dynamic linkages among the gold market, US dollar and crude oil market

    NASA Astrophysics Data System (ADS)

    Mo, Bin; Nie, He; Jiang, Yonghong

    2018-02-01

    This paper aims to examine the dynamic linkages among the gold market, US dollar and crude oil market. The analysis also delves more deeply into the effect of the global financial crisis on the short-term relationship. We use fractional cointegration to analyze the long-term memory feature of these volatility processes to investigate whether they are tied through a common long-term equilibrium. The DCC-MGARCH model is employed to investigate the time-varying long-term linkages among these markets. The Krystou-Labys non-linear asymmetric Granger causality method is used to examine the effect of the financial crisis. We find that (i) there is clearly a long-term dependence among these markets; (ii) the dynamic gold-oil relationship is always positive and the oil-dollar relationship is always negative; and (iii) after the crisis, we can observe evidence of a positive non-linear causal relationship from gold to US dollar and US dollar to crude oil, and a negative non-linear causal relationship from US dollar to gold. Investors who want to construct their optimal portfolios and policymakers who aim to make effective macroeconomic policies should take these findings into account.

  7. An Exploratory Study of Resting Cardiac Rate and Variability from the Last Trimester of Prenatal Life Through the First Year of Postnatal Life

    ERIC Educational Resources Information Center

    Lewis, Michael; And Others

    1970-01-01

    The data indicate no relationship between maternal and fetal data. Moreover, there are clear developmental patterns of resting cardiac response over the first year of life, with rate and variability showing linear decreases. (Author/WY)

  8. Defining the "older" crash victim: the relationship between age and serious injury in motor vehicle crashes.

    PubMed

    Newgard, Craig D

    2008-07-01

    Age is often used as a predictor of injury and mortality in motor vehicle crashes (MVCs), however, the age that defines an "older" occupant in terms of injury-risk remains unclear, as do specific injury patterns associated with increasing age. The objective of this study was to evaluate the relationship between age and serious injury (including injury patterns) for occupants involved in MVCs. This was a retrospective cohort study using a national population-based cohort of adult front-seat occupants involved in MVCs and included in the National Automotive Sampling System Crashworthiness Data System database from 1995 to 2006. The primary outcome was serious injury, defined as an abbreviated injury scale (AIS) score >/=3 in any body region. Anatomic injury patterns were also assessed by age. One hundred thousand one hundred and fifty-six adult front-seat occupants were included in the analysis, of which 14,128 (2%) were seriously injured. Age was a strong predictor of serious injury using a variety of different age covariates (categorical, continuous, and polynomial) in multivariable regression models (p<0.0001 for all). There was evidence of a strong non-linear relationship between age and serious injury (p<0.001 for comparison of non-linear to linear representation of age). There was no age that clearly defined an "older" occupant by injury risk, as the odds of injury increased with increasing age across all age groups. The proportion of serious head and extremity injuries gradually increased with increasing age, while serious chest injuries markedly increased after 60 years. Age is a strong predictor of serious injury from motor vehicle trauma, the risk of which increases in non-linear fashion as age increases. There is no specific age that clearly defines an "older" occupant by injury risk.

  9. Econometric testing on linear and nonlinear dynamic relation between stock prices and macroeconomy in China

    NASA Astrophysics Data System (ADS)

    Borjigin, Sumuya; Yang, Yating; Yang, Xiaoguang; Sun, Leilei

    2018-03-01

    Many researchers have realized that there is a strong correlation between stock prices and macroeconomy. In order to make this relationship clear, a lot of studies have been done. However, the causal relationship between stock prices and macroeconomy has still not been well explained. A key point is that, most of the existing research adopts linear and stable models to investigate the correlation of stock prices and macroeconomy, while the real causality of that may be nonlinear and dynamic. To fill this research gap, we investigate the nonlinear and dynamic causal relationships between stock prices and macroeconomy. Based on the case of China's stock prices and acroeconomy measures from January 1992 to March 2017, we compare the linear Granger causality test models with nonlinear ones. Results demonstrate that the nonlinear dynamic Granger causality is much stronger than linear Granger causality. From the perspective of nonlinear dynamic Granger causality, China's stock prices can be viewed as "national economic barometer". On the one hand, this study will encourage researchers to take nonlinearity and dynamics into account when they investigate the correlation of stock prices and macroeconomy; on the other hand, our research can guide regulators and investors to make better decisions.

  10. Estimation of sea surface temperature from remote measurements in the 11-13 micron window region

    NASA Technical Reports Server (NTRS)

    Prabhakara, C.; Conrath, B. J.; Kunde, V. G.

    1972-01-01

    The Nimbus-4 IRIS data was examined in the spectral region 775 to 1250/cm (8-13 microns) for useful information to determine the sea surface temperature. The high spectral resolution data of IRIS was degraded to low resolution by averaging to simulate a multi-channel radiometer in the window region. These simulated data show that within the region 775-975/cm (12.9-10.25 microns) the brightness temperatures are linearly related to the absorption parameters. Such a linear relationship is observed over cloudy as well as clear regions and over a wide range of latitudes. From this linear relationship it is feasible to correct for the atmospheric attenuation and get the sea surface temperature, accurate to within 1 K, in a cloud free field of view. The information about the cloud cover is taken from the TV pictures and BUV albedo measurements on board the Nimbus-4 satellite.

  11. Patterns of shading tolerance determined from experimental ...

    EPA Pesticide Factsheets

    An extensive review of the experimental literature on seagrass shading evaluated the relationship between experimental light reductions, duration of experiment and seagrass response metrics to determine whether there were consistent statistical patterns. There were highly significant linear relationships of both percent biomass and percent shoot density reduction versus percent light reduction (versus controls), although unexplained variation in the data were high. Duration of exposure affected extent of response for both metrics, but was more clearly a factor in biomass response. Both biomass and shoot density showed linear responses to duration of light reduction for treatments 60%. Unexplained variation was again high, and greater for shoot density than biomass. With few exceptions, regressions of both biomass and shoot density on light reduction for individual species and for genera were statistically significant, but also tended to show high degrees of variability in data. Multivariate regressions that included both percent light reduction and duration of reduction as dependent variables increased the percentage of variation explained in almost every case. Analysis of response data by seagrass life history category (Colonizing, Opportunistic, Persistent) did not yield clearly separate response relationships in most cases. Biomass tended to show somewhat less variation in response to light reduction than shoot density, and of the two, may be the prefe

  12. Estimating potency for the Emax-model without attaining maximal effects.

    PubMed

    Schoemaker, R C; van Gerven, J M; Cohen, A F

    1998-10-01

    The most widely applied model relating drug concentrations to effects is the Emax model. In practice, concentration-effect relationships often deviate from a simple linear relationship but without reaching a clear maximum because a further increase in concentration might be associated with unacceptable or distorting side effects. The parameters for the Emax model can only be estimated with reasonable precision if the curve shows sign of reaching a maximum, otherwise both EC50 and Emax estimates may be extremely imprecise. This paper provides a solution by introducing a new parameter (S0) equal to Emax/EC50 that can be used to characterize potency adequately even if there are no signs of a clear maximum. Simulations are presented to investigate the nature of the new parameter and published examples are used as illustration.

  13. Non-linear effects of the built environment on automobile-involved pedestrian crash frequency: A machine learning approach.

    PubMed

    Ding, Chuan; Chen, Peng; Jiao, Junfeng

    2018-03-01

    Although a growing body of literature focuses on the relationship between the built environment and pedestrian crashes, limited evidence is provided about the relative importance of many built environment attributes by accounting for their mutual interaction effects and their non-linear effects on automobile-involved pedestrian crashes. This study adopts the approach of Multiple Additive Poisson Regression Trees (MAPRT) to fill such gaps using pedestrian collision data collected from Seattle, Washington. Traffic analysis zones are chosen as the analytical unit. The effects of various factors on pedestrian crash frequency investigated include characteristics the of road network, street elements, land use patterns, and traffic demand. Density and the degree of mixed land use have major effects on pedestrian crash frequency, accounting for approximately 66% of the effects in total. More importantly, some factors show clear non-linear relationships with pedestrian crash frequency, challenging the linearity assumption commonly used in existing studies which employ statistical models. With various accurately identified non-linear relationships between the built environment and pedestrian crashes, this study suggests local agencies to adopt geo-spatial differentiated policies to establish a safe walking environment. These findings, especially the effective ranges of the built environment, provide evidence to support for transport and land use planning, policy recommendations, and road safety programs. Copyright © 2018 Elsevier Ltd. All rights reserved.

  14. Statistical Tests of System Linearity Based on the Method of Surrogate Data

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hunter, N.; Paez, T.; Red-Horse, J.

    When dealing with measured data from dynamic systems we often make the tacit assumption that the data are generated by linear dynamics. While some systematic tests for linearity and determinism are available - for example the coherence fimction, the probability density fimction, and the bispectrum - fi,u-ther tests that quanti$ the existence and the degree of nonlinearity are clearly needed. In this paper we demonstrate a statistical test for the nonlinearity exhibited by a dynamic system excited by Gaussian random noise. We perform the usual division of the input and response time series data into blocks as required by themore » Welch method of spectrum estimation and search for significant relationships between a given input fkequency and response at harmonics of the selected input frequency. We argue that systematic tests based on the recently developed statistical method of surrogate data readily detect significant nonlinear relationships. The paper elucidates the method of surrogate data. Typical results are illustrated for a linear single degree-of-freedom system and for a system with polynomial stiffness nonlinearity.« less

  15. Mathematical optimization of high dose-rate brachytherapy—derivation of a linear penalty model from a dose-volume model

    NASA Astrophysics Data System (ADS)

    Morén, B.; Larsson, T.; Carlsson Tedgren, Å.

    2018-03-01

    High dose-rate brachytherapy is a method for cancer treatment where the radiation source is placed within the body, inside or close to a tumour. For dose planning, mathematical optimization techniques are being used in practice and the most common approach is to use a linear model which penalizes deviations from specified dose limits for the tumour and for nearby organs. This linear penalty model is easy to solve, but its weakness lies in the poor correlation of its objective value and the dose-volume objectives that are used clinically to evaluate dose distributions. Furthermore, the model contains parameters that have no clear clinical interpretation. Another approach for dose planning is to solve mixed-integer optimization models with explicit dose-volume constraints which include parameters that directly correspond to dose-volume objectives, and which are therefore tangible. The two mentioned models take the overall goals for dose planning into account in fundamentally different ways. We show that there is, however, a mathematical relationship between them by deriving a linear penalty model from a dose-volume model. This relationship has not been established before and improves the understanding of the linear penalty model. In particular, the parameters of the linear penalty model can be interpreted as dual variables in the dose-volume model.

  16. How things fall apart: understanding the nature of internalizing through its relationship with impairment.

    PubMed

    Markon, Kristian E

    2010-08-01

    The literature suggests that internalizing psychopathology relates to impairment incrementally and gradually. However, the form of this relationship has not been characterized. This form is critical to understanding internalizing psychopathology, as it is possible that internalizing may accelerate in effect at some level of severity, defining a natural boundary of abnormality. Here, a novel method-semiparametric structural equation modeling-was used to model the relationship between internalizing and impairment in a sample of 8,580 individuals from the 2000 British Office for National Statistics Survey of Psychiatric Morbidity, a large, population-representative study of psychopathology. This method allows one to model relationships between latent internalizing and impairment without assuming any particular form a priori and to compare models in which the relationship is constant and linear. Results suggest that the relationship between internalizing and impairment is in fact linear and constant across the entire range of internalizing variation and that it is impossible to nonarbitrarily define a specific level of internalizing beyond which consequences suddenly become catastrophic in nature. Results demonstrate the phenomenological continuity of internalizing psychopathology, highlight the importance of impairment as well as symptoms, and have clear implications for defining mental disorder. Copyright 2010 APA, all rights reserved

  17. The artificial neural network modelling of the piezoelectric actuator vibrations using laser displacement sensor

    NASA Astrophysics Data System (ADS)

    Paralı, Levent; Sarı, Ali; Kılıç, Ulaş; Şahin, Özge; Pěchoušek, Jiří

    2017-09-01

    We report an improvement of the artificial neural network (ANN) modelling of a piezoelectric actuator vibration based on the experimental data. The controlled vibrations of an actuator were obtained by utilizing the swept-sine signal excitation. The peak value in the displacement signal response was measured by a laser displacement sensor. The piezoelectric actuator was modelled in both linear and nonlinear operating range. A consistency from 90.3 up to 98.9% of ANN modelled output values and experimental ones was reached. The obtained results clearly demonstrate exact linear relationship between the ANN model and experimental values.

  18. Relationships for electron-vibrational coupling in conjugated π organic systems

    NASA Astrophysics Data System (ADS)

    O'Neill, L.; Lynch, P.; McNamara, M.; Byrne, H. J.

    2005-06-01

    A series of π conjugated systems were studied by absorption, photoluminescence and vibrational spectroscopy. As is common for these systems, a linear relationship between the positioning of the absorption and photoluminescence maxima plotted against inverse conjugation length is observed. The relationships are in good agreement with the simple particle in a box method, one of the earliest descriptions of the properties of one-dimensional organic molecules. In addition to the electronic transition energies, it was observed that the Stokes shift also exhibited a well-defined relationship with increasing conjugation length, implying a correlation between the electron-vibrational coupling and chain length. This correlation is further examined using Raman spectroscopy, whereby the integrated Raman scattering is seen to behave superlinearly with chain length. There is a clear indication that the vibrational activity and thus nonradiative decay processes are controllable through molecular structure. The correlations between the Stokes energies and the vibrational structure are also observed in a selection of PPV based polymers and a clear trend of increasing luminescence efficiency with decreasing vibrational activity and Stokes shift is observable. The implications of such structure property relationships in terms of materials design are discussed.

  19. Modification of the acid/base properties of γ-Al2O3 by oxide additives: An ethanol TPD investigation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kwak, Ja Hun; Lee, Jaekyoung; Szanyi, Janos

    2016-02-26

    The electronic properties of oxide-modified γ Al2O3 surfaces were investigated by using ethanol TPD. Ethanol TPD showed remarkable sensitivity toward the surface structures and electronic properties of the aluminas modified by various transition metal oxides. Maximum desorption rates for the primary product of ethanol adsorption, ethylene, were observed at 225 °C on non-modified γ-Al2O3. Desorption temperature of ethanol over a γ Al2O3 samples with different amounts of BaO linearly increased with increasing loading. On the contrary, ethanol desorption temperature on Pt modified γ-Al2O3 after calcined at 500 oC linearly decreased with increasing Pt loading. These results clearly suggested that themore » acid/base properties of the γ-Al2O3 surface can be strongly affected by ad-atoms. For confirming these arguments, we performed ethanol TPD experiments on various oxide modified γ-Al2O3 and normalized the maximum desorption temperatures based on the same number of oxide dopants. These normalized ethanol desorption temperatures linearly correlate with the electronegativity of the metal atom in the oxide. This linear relationship clearly demonstrates that the acidic properties of alumina surfaces can be systematically changed by ad-atoms.« less

  20. Polyphenolic, polysaccharide and oligosaccharide composition of Tempranillo red wines and their relationship with the perceived astringency.

    PubMed

    Quijada-Morín, Natalia; Williams, Pascale; Rivas-Gonzalo, Julián C; Doco, Thierry; Escribano-Bailón, M Teresa

    2014-07-01

    The influence of the proanthocyanidic, polysaccharide and oligosaccharide composition on astringency perception of Tempranillo wines has been evaluated. Statistical analyses revealed the existence of relationships between chemical composition and perceived astringency. Proanthocyanidic subunit distribution had the strongest contribution to the multiple linear regression (MLR) model. Polysaccharide families showed clear opposition to astringency perception according to principal component analysis (PCA) results, being stronger for mannoproteins and rhamnogalacturonan-II (RG-II), but only Polysaccharides Rich in Arabinose and Galactose (PRAGs) were considered in the final fitted MLR model, which explained 96.8% of the variability observed in the data. Oligosaccharides did not show a clear opposition, revealing that structure and size of carbohydrates are important for astringency perception. Mannose and galactose residues in the oligosaccharide fraction are positively related to astringency perception, probably because its presence is consequence of the degradation of polysaccharides. Copyright © 2014 Elsevier Ltd. All rights reserved.

  1. Zinc affects differently growth, photosynthesis, antioxidant enzyme activities and phytochelatin synthase expression of four marine diatoms.

    PubMed

    Nguyen-Deroche, Thi Le Nhung; Caruso, Aurore; Le, Thi Trung; Bui, Trang Viet; Schoefs, Benoît; Tremblin, Gérard; Morant-Manceau, Annick

    2012-01-01

    Zinc-supplementation (20 μM) effects on growth, photosynthesis, antioxidant enzyme activities (superoxide dismutase, ascorbate peroxidase, catalase), and the expression of phytochelatin synthase gene were investigated in four marine diatoms (Amphora acutiuscula, Nitzschia palea, Amphora coffeaeformis and Entomoneis paludosa). Zn-supplementation reduced the maximum cell density. A linear relationship was found between the evolution of gross photosynthesis and total chlorophyll content. The Zn treatment decreased the electron transport rate except in A. coffeaeformis and in E. paludosa at high irradiance. A linear relationship was found between the efficiency of light to evolve oxygen and the size of the light-harvesting antenna. The external carbonic anhydrase activity was stimulated in Zn-supplemented E. paludosa but was not correlated with an increase of photosynthesis. The total activity of the antioxidant enzymes did not display any clear increase except in ascorbate peroxidase activity in N. palea. The phytochelatin synthase gene was identified in the four diatoms, but its expression was only revealed in N. palea, without a clear difference between control and Zn-supplemented cells. Among the four species, A. paludosa was the most sensitive and A. coffeaeformis, the most tolerant. A. acutiuscula seemed to be under metal starvation, whereas, to survive, only N. palea developed several stress responses.

  2. Zinc Affects Differently Growth, Photosynthesis, Antioxidant Enzyme Activities and Phytochelatin Synthase Expression of Four Marine Diatoms

    PubMed Central

    Nguyen-Deroche, Thi Le Nhung; Caruso, Aurore; Le, Thi Trung; Bui, Trang Viet; Schoefs, Benoît; Tremblin, Gérard; Morant-Manceau, Annick

    2012-01-01

    Zinc-supplementation (20 μM) effects on growth, photosynthesis, antioxidant enzyme activities (superoxide dismutase, ascorbate peroxidase, catalase), and the expression of phytochelatin synthase gene were investigated in four marine diatoms (Amphora acutiuscula, Nitzschia palea, Amphora coffeaeformis and Entomoneis paludosa). Zn-supplementation reduced the maximum cell density. A linear relationship was found between the evolution of gross photosynthesis and total chlorophyll content. The Zn treatment decreased the electron transport rate except in A. coffeaeformis and in E. paludosa at high irradiance. A linear relationship was found between the efficiency of light to evolve oxygen and the size of the light-harvesting antenna. The external carbonic anhydrase activity was stimulated in Zn-supplemented E. paludosa but was not correlated with an increase of photosynthesis. The total activity of the antioxidant enzymes did not display any clear increase except in ascorbate peroxidase activity in N. palea. The phytochelatin synthase gene was identified in the four diatoms, but its expression was only revealed in N. palea, without a clear difference between control and Zn-supplemented cells. Among the four species, A. paludosa was the most sensitive and A. coffeaeformis, the most tolerant. A. acutiuscula seemed to be under metal starvation, whereas, to survive, only N. palea developed several stress responses. PMID:22645501

  3. Geotechnical and mineralogical characteristics of marl deposits in Jordan

    NASA Astrophysics Data System (ADS)

    Shaqour, Fathi M.; Jarrar, Ghaleb; Hencher, Steve; Kuisi, Mostafa

    2008-10-01

    Marls and marly limestone deposits cover most of Northern Jordan, where Amman City and its suburbs are located. These deposits serve as foundations for most buildings and roads as well as fill material for structural back filling, especially road bases and sub-bases. The present study aims at investigating the geotechnical characteristics and mineral composition of the marl units of these deposits through field investigations and laboratory testing. Using X-ray diffraction technique along with chemical analysis, representative samples of marl horizons were tested for mineral composition, and for a set of index and geotechnical properties including: specific gravity, grain size, Atterberg limits, Proctor compaction and shear strength properties. The test results show a positive linear relationship as expected between the clay content and both liquid and plastic limits. The tests results also show an inverse linear relationship between the clay content and the maximum dry density in both standard and modified compaction. This is attributed to the adsorption of water by the clay minerals. The relationship is more prominent in the case of modified compaction test. The results also indicate a similar relationship for the angle of internal friction. No clear correlation between cohesion and clay content was apparent.

  4. Dominance relationships in a family pack of captive arctic wolves (Canis lupus arctos): the influence of competition for food, age and sex

    PubMed Central

    Lazzaroni, Martina; Marshall-Pescini, Sarah

    2016-01-01

    Background Dominance is one of the most pervasive concepts in the study of wolf social behaviour but recently its validity has been questioned. For some authors, the bonds between members of wolf families are better described as parent-offspring relationships and the concept of dominance should be used just to evaluate the social dynamics of non-familial captive pack members (e.g., Mech & Cluff, 2010). However, there is a dearth of studies investigating dominance relationships and its correlates in wolf family packs. Methods Here, we applied a combination of the most commonly used quantitative methods to evaluate the dominance relationships in a captive family pack of 19 Arctic wolves. Results We found a significant linear and completely transitive hierarchy based on the direction of submissive behaviours and found that dominance relationships were not influenced by the competitive contexts (feeding vs. non-feeding context). A significant linear hierarchy also emerges amongst siblings once the breeding pair (the two top-ranking individuals) is removed from analyses. Furthermore, results suggest that wolves may use greeting behaviour as a formal signal of subordination. Whereas older wolves were mostly dominant over younger ones, no clear effect of sex was found. However, frequency of agonistic (submissive, dominant and aggressive) behaviours was higher between female–female and male–male dyads than female–male dyads and sex-separated linear hierarchies showed a stronger linearity than the mixed one. Furthermore, dominance status was conveyed through different behavioural categories during intra-sexual and inter-sexual interactions. Discussion Current results highlight the importance of applying a systematic methodology considering the individuals’ age and sex when evaluating the hierarchical structure of a social group. Moreover, they confirm the validity of the concept of dominance relationships in describing the social bonds within a family pack of captive wolves. PMID:27904806

  5. Temporal and radial variation of the solar wind temperature-speed relationship

    NASA Astrophysics Data System (ADS)

    Elliott, H. A.; Henney, C. J.; McComas, D. J.; Smith, C. W.; Vasquez, B. J.

    2012-09-01

    The solar wind temperature (T) and speed (V) are generally well correlated at ˜1 AU, except in Interplanetary Coronal Mass Ejections where this correlation breaks down. We perform a comprehensive analysis of both the temporal and radial variation in the temperature-speed (T-V) relationship of the non-transient wind, and our analysis provides insight into both the causes of the T-V relationship and the sources of the temperature variability. Often at 1 AU the speed-temperature relationship is well represented by a single linear fit over a speed range spanning both the slow and fast wind. However, at times the fast wind from coronal holes can have a different T-V relationship than the slow wind. A good example of this was in 2003 when there was a very large and long-lived outward magnetic polarity coronal hole at low latitudes that emitted wind with speeds as fast as a polar coronal hole. The long-lived nature of the hole made it possible to clearly distinguish that some holes can have a different T-V relationship. In an earlier ACE study, we found that both the compressions and rarefactions T-V curves are linear, but the compression curve is shifted to higher temperatures. By separating compressions and rarefactions prior to determining the radial profiles of the solar wind parameters, the importance of dynamic interactions on the radial evolution of the solar wind parameters is revealed. Although the T-V relationship at 1 AU is often well described by a single linear curve, we find that the T-V relationship continually evolves with distance. Beyond ˜2.5 AU the differences between the compressions and rarefactions are quite significant and affect the shape of the overall T-V distribution to the point that a simple linear fit no longer describes the distribution well. Since additional heating of the ambient solar wind outside of interaction regions can be associated with Alfvénic fluctuations and the turbulent energy cascade, we also estimate the heating rate radial profile from the solar wind speed and temperature measurements.

  6. Diatom diversity in chronically versus episodically acidified adirondack streams

    USGS Publications Warehouse

    Passy, S.I.; Ciugulea, I.; Lawrence, G.B.

    2006-01-01

    The relationship between algal species richness and diversity, and pH is controversial. Furthermore, it is still unknown how episodic stream acidification following atmospheric deposition affects species richness and diversity. Here we analyzed water chemistry and diatom epiphyton dynamics and showed their contrasting behavior in chronically vs. episodically acidic streams in the Adirondack region. Species richness and diversity were significantly higher in the chronically acidic brown water stream, where organic acidity was significantly higher and the ratio of inorganic to organic monomeric aluminum significantly lower. Conversely, in the episodically acidic clear water stream, the inorganic acidity and pH were significantly higher and the diatom communities were very species-poor. This suggests that episodic acidification in the Adirondacks may be more stressful for stream biota than chronic acidity. Strong negative linear relationships between species diversity, Eunotia exigua, and dissolved organic carbon against pH were revealed after the influence of non-linear temporal trends was partialled out using a novel way of temporal modeling. ?? 2006 WILEY-VCH Verlag GmbH & Co. KGaA.

  7. Fish and invertebrate flow-biology relationships to support the determination of ecological flows for North Carolina

    USGS Publications Warehouse

    Phelan, Jennifer; Cuffney, Thomas F.; Patterson, Lauren A.; Eddy, Michele; Dykes, Robert; Pearsall, Sam; Goudreau, Chris; Mead, Jim; Tarver, Fred

    2017-01-01

    A method was developed to characterize fish and invertebrate responses to flow alteration in the state of North Carolina. This method involved using 80th percentile linear quantile regressions to relate six flow metrics to the diversity of riffle-run fish and benthic Ephemeroptera, Plecoptera, and Trichoptera (EPT) richness. All twelve flow-biology relationships were found to be significant, with both benthos and fish showing negative responses to ecodeficits and reductions in flow. The responses of benthic richness to reduced flows were consistent and generally greater than that of fish diversity. However, the riffle-run fish guild showed the greatest reductions in diversity in response to summer ecodeficits. The directional consistency and differential seasonal sensitivities of fish and invertebrates to reductions in flow highlight the need to consider seasonality when managing flows. In addition, all relationships were linear, and therefore do not provide clear thresholds to support ecological flow determinations and flow prescriptions to prevent the degradation of fish and invertebrate communities in North Carolina rivers and streams. A method of setting ecological flows based on the magnitude of change in biological condition that is acceptable to society is explored.

  8. The Compositional HJ-Biplot—A New Approach to Identifying the Links among Bioactive Compounds of Tomatoes

    PubMed Central

    Hernández Suárez, Marcos; Molina Pérez, Daniel; Rodríguez-Rodríguez, Elena M.; Díaz Romero, Carlos; Espinosa Borreguero, Francisco; Galindo-Villardón, Purificación

    2016-01-01

    Tomatoes have been described as a functional food because of their particular composition of different bioactive compounds. In this study, the proximate composition, minerals and trace elements, and antioxidant compounds were determined in two tomato cultivars (Mariana and Dunkan) that were grown in Gran Canaria (Spain) either conventionally or hydroponically. Although compositional data of this type require being subjected to the specific statistical techniques of compositional analysis, this approach has not usually been considered in this context. In the present case, a compositional Mann–Whitney U test of the data showed significant differences for each factor (cultivar and cultivation system) in several of the compositional variables studied. For the differences between cultivars, these parameters were the protein, Mg, lycopene, ascorbic acid, citric acid, and fumaric acid contents. For the differences between cultivation systems, they were mainly those of the mineral and trace elements group. Although one-year data are insufficient to make clear relationship among compounds because more repetitions in several localities and years are necessary, the compositional HJ-biplot (in which the links provide estimates of the linear relationship among variables) results agreed with other scientific results about linear relationship among some compounds analyzed. PMID:27827839

  9. The relationship between perceived discomfort of static posture holding and posture holding time.

    PubMed

    Ogutu, Jack; Park, Woojin

    2015-01-01

    Few studies have investigated mathematical characteristics of the discomfort-time relationship during prolonged static posture holding (SPH) on an individual basis. Consequently, the discomfort-time relationship is not clearly understood at individual trial level. The objective of this study was to examine discomfort-time sequence data obtained from a large number of maximum-duration SPH trials to understand the perceived discomfort-posture holding time relationship at the individual SPH trial level. Thirty subjects (15 male, 15 female) participated in this study as paid volunteers. The subjects performed maximum-duration SPH trials employing 12 different wholebody static postures. The hand-held load for all the task trials was a ``generic'' box weighing 2 kg. Three mathematical functions, that is, linear, logarithmic and power functions were examined as possible mathematical models for representing individual discomfort-time profiles of SPH trials. Three different time increase patterns (negatively accelerated, linear and positively accelerated) were observed in the discomfort-time sequences data. The power function model with an additive constant term was found to adequately fit most (96.4%) of the observed discomfort-time sequences, and thus, was recommended as a general mathematical representation of the perceived discomfort-posture holding time relationship in SPH. The new knowledge on the nature of the discomfort-time relationship in SPH and the power function representation found in this study will facilitate analyzing discomfort-time data of SPH and developing future posture analysis tools for work-related discomfort control.

  10. Thermal Expansion of Fluorapatite-Chlorapatite Solid Solutions

    NASA Astrophysics Data System (ADS)

    Hovis, G. L.; Abraham, T.; Hudacek, W.; Wildermuth, S.; Scott, B.; Altomare, C.; Medford, A.; Conlon, M.; Morris, M.; Leaman, A.; Almer, C.; Tomaino, G.; Harlov, D. E.

    2014-12-01

    X-ray powder diffraction experiments have been performed on fifteen fluorapatite-chlorapatite solid solutions synthesized and chemically characterized at the GeoForschungsZentrum - Potsdam (Hovis and Harlov, 2010; Schettler, Gottschalk, and Harlov, 2011), as well as two natural near-end-member samples, from room temperature to ~900 °C at 50 to 75 °C intervals. NIST 640a Si was employed as an internal standard; data from Parrish (1953) were used to determine Si peak positions at elevated temperatures. Unit-cell parameters calculated using the software of Holland and Redfern (1997) result in volume-temperature (V-T) plots that are linear or slightly concave up (V plotted as the vertical axis) over the T range investigated. Relations for the "a" and "c" unit-cell dimensions with T for these hexagonal minerals are nearly linear but, as with V, commonly improved by quadratic fits to the data. Coefficients of thermal expansion for volume (αV), calculated as (1/V0°C) x (ΔV/ΔT) based on linear V-T relationships, mostly fall within the range 42 ± 2 x 10-6 deg-1 and show no obvious dependence on composition. Thermal expansion coefficients for individual unit-cell axes, however, do show clear relationships to composition, αa increasing from ~9.5 to ~13.5 x 10-6 deg-1 and αc decreasing from ~19.5 to ~13 x 10-6 deg-1 from the Cl to the F end member. Clearly, a compensating structural relationship accounts for the observed relationships. Such compositional dependence was not seen in the thermal expansion data for F-OH apatite solid solutions (Hovis, Scott, Altomare, Leaman, Morris, and Tomaino, American Mineralogist, in press). This difference can be explained by the similar sizes of F- and (OH)- versus the much greater size contrast between F- and Cl-. Sincere thanks to the National Science Foundation for support of this work, which has provided numerous research experiences for Lafayette College undergraduates. Thanks also to the Earth Sciences Department, University of Cambridge, for providing X-ray facilities for a portion of these measurements. Finally, thanks to Jeff Post, National Museum of Natural History, and George Harlow, American Museum of Natural History, for providing the natural fluorapatite (NMNH 144954-3, Durango, Mexico) and chlorapatite (AMNH 23101, Kragero, Norway) samples, respectively.

  11. Thermal Expansion of Fluorapatite-Chlorapatite Solid Solutions

    NASA Astrophysics Data System (ADS)

    Hovis, Guy; Abraham, Tony; Hudacek, William; Wildermuth, Sarah; Scott, Brian; Altomare, Caitlin; Medford, Aaron; Conlon, Maricate; Morris, Matthew; Leaman, Amanda; Almer, Christine; Tomaino, Gary; Harlov, Daniel

    2015-04-01

    X-ray powder diffraction experiments have been performed on fifteen fluorapatite-chlorapatite solid solutions synthesized and chemically characterized at the GeoForschungsZentrum - Potsdam (Hovis and Harlov, 2010; Schettler, Gottschalk, and Harlov, 2011), as well as two natural near-end-member samples, from room temperature to ~900 °C at 50 to 75 °C intervals. NIST 640a Si was employed as an internal standard; data from Parrish (1953) were used to determine Si peak positions at elevated temperatures. Unit-cell parameters calculated using the software of Holland and Redfern (1997) result in volume-temperature (V-T) plots that are linear or slightly concave up (V plotted as the vertical axis) over the T range investigated. Relations for the "a" and "c" unit-cell dimensions with T for these hexagonal minerals are nearly linear, but as with V, commonly improved by quadratic fits to the data. Coefficients of thermal expansion for volume (αV ), calculated as (1/V0°C) x (ΔV/ΔT) based on linear V-T relationships, mostly fall within the range 42 ± 2 x 10-6 deg-1 and show no obvious dependence on composition. Thermal expansion coefficients for individual unit-cell axes, however, do show clear relationships to composition, αa increasing from ~9.5 to ~13.5 x 10-6 deg-1 and αc decreasing from ~19.5 to ~13 x 10-6 deg-1 from the Cl to the F end member. Clearly, a compensating structural relationship accounts for the observed relationships. Such compositional dependence was not seen in the thermal expansion data for F-OH apatite solid solutions (Hovis, Scott, Altomare, Leaman, Morris, and Tomaino, American Mineralogist, in press). This difference can be explained by the similar sizes of F- and (OH)- versus the much greater size contrast between F- and Cl-. Sincere thanks to the National Science Foundation for support of this work, which has provided numerous research experiences for Lafayette College undergraduates. Thanks also to the Earth Sciences Department, University of Cambridge, for providing X-ray facilities for a portion of these measurements. Finally, thanks to Jeff Post, National Museum of Natural History, and George Harlow, American Museum of Natural History, for providing the natural fluorapatite (NMNH 144954-3, Durango, Mexico) and chlorapatite (AMNH 23101, Kragero, Norway) samples, respectively.

  12. Comparison of co-expression measures: mutual information, correlation, and model based indices.

    PubMed

    Song, Lin; Langfelder, Peter; Horvath, Steve

    2012-12-09

    Co-expression measures are often used to define networks among genes. Mutual information (MI) is often used as a generalized correlation measure. It is not clear how much MI adds beyond standard (robust) correlation measures or regression model based association measures. Further, it is important to assess what transformations of these and other co-expression measures lead to biologically meaningful modules (clusters of genes). We provide a comprehensive comparison between mutual information and several correlation measures in 8 empirical data sets and in simulations. We also study different approaches for transforming an adjacency matrix, e.g. using the topological overlap measure. Overall, we confirm close relationships between MI and correlation in all data sets which reflects the fact that most gene pairs satisfy linear or monotonic relationships. We discuss rare situations when the two measures disagree. We also compare correlation and MI based approaches when it comes to defining co-expression network modules. We show that a robust measure of correlation (the biweight midcorrelation transformed via the topological overlap transformation) leads to modules that are superior to MI based modules and maximal information coefficient (MIC) based modules in terms of gene ontology enrichment. We present a function that relates correlation to mutual information which can be used to approximate the mutual information from the corresponding correlation coefficient. We propose the use of polynomial or spline regression models as an alternative to MI for capturing non-linear relationships between quantitative variables. The biweight midcorrelation outperforms MI in terms of elucidating gene pairwise relationships. Coupled with the topological overlap matrix transformation, it often leads to more significantly enriched co-expression modules. Spline and polynomial networks form attractive alternatives to MI in case of non-linear relationships. Our results indicate that MI networks can safely be replaced by correlation networks when it comes to measuring co-expression relationships in stationary data.

  13. Derivation of an applied nonlinear Schroedinger equation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pitts, Todd Alan; Laine, Mark Richard; Schwarz, Jens

    We derive from first principles a mathematical physics model useful for understanding nonlinear optical propagation (including filamentation). All assumptions necessary for the development are clearly explained. We include the Kerr effect, Raman scattering, and ionization (as well as linear and nonlinear shock, diffraction and dispersion). We explain the phenomenological sub-models and each assumption required to arrive at a complete and consistent theoretical description. The development includes the relationship between shock and ionization and demonstrates why inclusion of Drude model impedance effects alters the nature of the shock operator. Unclassified Unlimited Release

  14. Handedness and hemispheric language dominance in healthy humans.

    PubMed

    Knecht, S; Dräger, B; Deppe, M; Bobe, L; Lohmann, H; Flöel, A; Ringelstein, E B; Henningsen, H

    2000-12-01

    In most people the left hemisphere of the brain is dominant for language. Because of the increased incidence of atypical right-hemispheric language in left-handed neurological patients, a systematic association between handedness and dominance has long been suspected. To clarify the relationship between handedness and language dominance in healthy subjects, we measured lateralization directly by functional transcranial Doppler sonography in 326 healthy individuals using a word-generation task. The incidence of right-hemisphere language dominance was found to increase linearly with the degree of left-handedness, from 4% in strong right-handers (handedness = 100) to 15% in ambidextrous individuals and 27% in strong left-handers (handedness = -100). The relationship could be approximated by the formula: f1.gif" BORDER="0">. These results clearly demonstrate that the relationship between handedness and language dominance is not an artefact of cerebral pathology but a natural phenomenon.

  15. Parameterization of clear-sky surface irradiance and its implications for estimation of aerosol direct radiative effect and aerosol optical depth

    PubMed Central

    Xia, Xiangao

    2015-01-01

    Aerosols impact clear-sky surface irradiance () through the effects of scattering and absorption. Linear or nonlinear relationships between aerosol optical depth (τa) and have been established to describe the aerosol direct radiative effect on (ADRE). However, considerable uncertainties remain associated with ADRE due to the incorrect estimation of (τa in the absence of aerosols). Based on data from the Aerosol Robotic Network, the effects of τa, water vapor content (w) and the cosine of the solar zenith angle (μ) on are thoroughly considered, leading to an effective parameterization of as a nonlinear function of these three quantities. The parameterization is proven able to estimate with a mean bias error of 0.32 W m−2, which is one order of magnitude smaller than that derived using earlier linear or nonlinear functions. Applications of this new parameterization to estimate τa from , or vice versa, show that the root-mean-square errors were 0.08 and 10.0 Wm−2, respectively. Therefore, this study establishes a straightforward method to derive from τa or estimate τa from measurements if water vapor measurements are available. PMID:26395310

  16. Reduction of respiratory ghosting motion artifacts in conventional two-dimensional multi-slice Cartesian turbo spin-echo: which k-space filling order is the best?

    PubMed

    Inoue, Yuuji; Yoneyama, Masami; Nakamura, Masanobu; Takemura, Atsushi

    2018-06-01

    The two-dimensional Cartesian turbo spin-echo (TSE) sequence is widely used in routine clinical studies, but it is sensitive to respiratory motion. We investigated the k-space orders in Cartesian TSE that can effectively reduce motion artifacts. The purpose of this study was to demonstrate the relationship between k-space order and degree of motion artifacts using a moving phantom. We compared the degree of motion artifacts between linear and asymmetric k-space orders. The actual spacing of ghost artifacts in the asymmetric order was doubled compared with that in the linear order in the free-breathing situation. The asymmetric order clearly showed less sensitivity to incomplete breath-hold at the latter half of the imaging period. Because of the actual number of partitions of the k-space and the temporal filling order, the asymmetric k-space order of Cartesian TSE was superior to the linear k-space order for reduction of ghosting motion artifacts.

  17. Estimation of available global solar radiation using sunshine duration over South Korea

    NASA Astrophysics Data System (ADS)

    Das, Amrita; Park, Jin-ki; Park, Jong-hwa

    2015-11-01

    Besides designing a solar energy system, accurate insolation data is also a key component for many biological and atmospheric studies. But solar radiation stations are not widely available due to financial and technical limitations; this insufficient number affects the spatial resolution whenever an attempt is made to construct a solar radiation map. There are several models in literature for estimating incoming solar radiation using sunshine fraction. Seventeen of such models among which 6 are linear and 11 non-linear, have been chosen for studying and estimating solar radiation on a horizontal surface over South Korea. The better performance of a non-linear model signifies the fact that the relationship between sunshine duration and clearness index does not follow a straight line. With such a model solar radiation over 79 stations measuring sunshine duration is computed and used as input for spatial interpolation. Finally monthly solar radiation maps are constructed using the Ordinary Kriging method. The cross validation results show good agreement between observed and predicted data.

  18. Activation of plantar flexor muscles is constrained by multiple muscle synergies rather than joint torques

    PubMed Central

    Suzuki, Takahito; Kinugasa, Ryuta; Fukashiro, Senshi

    2017-01-01

    Behavioral evidence has suggested that a small number of muscle synergies may be responsible for activating a variety of muscles. Nevertheless, such dimensionality reduction may also be explained using the perspective of alternative hypotheses, such as predictions based on linear combinations of joint torques multiplied by corresponding coefficients. To compare the explanatory capacity of these hypotheses for describing muscle activation, we enrolled 12 male volunteers who performed isometric plantar flexor contractions at 10–100% of maximum effort. During each plantar flexor contraction, the knee extensor muscles were isometrically contracted at 0%, 50%, or 100% of maximum effort. Electromyographic activity was recorded from the vastus lateralis, medial gastrocnemius (MG), lateral gastrocnemius (LG), and soleus muscles and quantified using the average rectified value (ARV). At lower plantar flexion torque, regression analysis identified a clear linear relationship between the MG and soleus ARVs and between the MG and LG ARVs, suggesting the presence of muscle synergy (r2 > 0.65). The contraction of the knee extensor muscles induced a significant change in the slope of this relationship for both pairs of muscles (MG × soleus, P = 0.002; MG × LG, P = 0.006). Similarly, the slope of the linear relationship between the plantar flexion torque and the ARV of the MG or soleus changed significantly with knee extensor contraction (P = 0.031 and P = 0.041, respectively). These results suggest that muscle synergies characterized by non-mechanical constraints are selectively recruited according to whether contraction of the knee extensor muscles is performed simultaneously, which is relatively consistent with the muscle synergy hypothesis. PMID:29107958

  19. Three-dimensional shape measurement and calibration for fringe projection by considering unequal height of the projector and the camera

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zhu Feipeng; Shi Hongjian; Bai Pengxiang

    In fringe projection, the CCD camera and the projector are often placed at equal height. In this paper, we will study the calibration of an unequal arrangement of the CCD camera and the projector. The principle of fringe projection with two-dimensional digital image correlation to acquire the profile of object surface is described in detail. By formula derivation and experiment, the linear relationship between the out-of-plane calibration coefficient and the y coordinate is clearly found. To acquire the three-dimensional (3D) information of an object correctly, this paper presents an effective calibration method with linear least-squares fitting, which is very simplemore » in principle and calibration. Experiments are implemented to validate the availability and reliability of the calibration method.« less

  20. Authoritarian parenting attitudes as a risk for conduct problems Results from a British national cohort study.

    PubMed

    Thompson, Anne; Hollis, Chris; Dagger, David Richards

    2003-04-01

    This study examines the associations, and possible causal relationship, between mothers' authoritarian attitudes to discipline and child behaviour using cross-sectional and prospective data from a large population sample surveyed in the 1970 British Cohort Study. Results show a clear linear relationship between the degree of maternal approval of authoritarian child-rearing attitudes and the rates of conduct problems at age 5 and age 10. This association is independent of the confounding effects of socio-economic status and maternal psychological distress. Maternal authoritarian attitudes independently predicted the development of conduct problems 5 years later at age 10. The results of this longitudinal study suggest that authoritarian parenting attitudes expressed by mothers may be of significance in the development of conduct problems.

  1. Stage-discharge relationship in tidal channels

    NASA Astrophysics Data System (ADS)

    Kearney, W. S.; Mariotti, G.; Deegan, L.; Fagherazzi, S.

    2016-12-01

    Long-term records of the flow of water through tidal channels are essential to constrain the budgets of sediments and biogeochemical compounds in salt marshes. Statistical models which relate discharge to water level allow the estimation of such records from more easily obtained records of water stage in the channel. While there is clearly structure in the stage-discharge relationship, nonlinearity and nonstationarity of the relationship complicates the construction of statistical stage-discharge models with adequate performance for discharge estimation and uncertainty quantification. Here we compare four different types of stage-discharge models, each of which is designed to capture different characteristics of the stage-discharge relationship. We estimate and validate each of these models on a two-month long time series of stage and discharge obtained with an Acoustic Doppler Current Profiler in a salt marsh channel. We find that the best performance is obtained by models which account for the nonlinear and time-varying nature of the stage-discharge relationship. Good performance can also be obtained from a simplified version of these models which approximates the fully nonlinear and time-varying models with a piecewise linear formulation.

  2. Observed correlation between the depth to base and top of gas hydrate occurrence from review of global drilling data

    NASA Astrophysics Data System (ADS)

    Riedel, M.; Collett, T. S.

    2017-07-01

    A global inventory of data from gas hydrate drilling expeditions is used to develop relationships between the base of structure I gas hydrate stability, top of gas hydrate occurrence, sulfate-methane transition depth, pressure (water depth), and geothermal gradients. The motivation of this study is to provide first-order estimates of the top of gas hydrate occurrence and associated thickness of the gas hydrate occurrence zone for climate-change scenarios, global carbon budget analyses, or gas hydrate resource assessments. Results from publically available drilling campaigns (21 expeditions and 52 drill sites) off Cascadia, Blake Ridge, India, Korea, South China Sea, Japan, Chile, Peru, Costa Rica, Gulf of Mexico, and Borneo reveal a first-order linear relationship between the depth to the top and base of gas hydrate occurrence. The reason for these nearly linear relationships is believed to be the strong pressure and temperature dependence of methane solubility in the absence of large difference in thermal gradients between the various sites assessed. In addition, a statistically robust relationship was defined between the thickness of the gas hydrate occurrence zone and the base of gas hydrate stability (in meters below seafloor). The relationship developed is able to predict the depth of the top of gas hydrate occurrence zone using observed depths of the base of gas hydrate stability within less than 50 m at most locations examined in this study. No clear correlation of the depth to the top and base of gas hydrate occurrences with geothermal gradient and sulfate-methane transition depth was identified.

  3. Observed correlation between the depth to base and top of gas hydrate occurrence from review of global drilling data

    USGS Publications Warehouse

    Riedel, Michael; Collett, Timothy S.

    2017-01-01

    A global inventory of data from gas hydrate drilling expeditions is used to develop relationships between the base of structure I gas hydrate stability, top of gas hydrate occurrence, sulfate-methane transition depth, pressure (water depth), and geothermal gradients. The motivation of this study is to provide first-order estimates of the top of gas hydrate occurrence and associated thickness of the gas hydrate occurrence zone for climate-change scenarios, global carbon budget analyses, or gas hydrate resource assessments. Results from publically available drilling campaigns (21 expeditions and 52 drill sites) off Cascadia, Blake Ridge, India, Korea, South China Sea, Japan, Chile, Peru, Costa Rica, Gulf of Mexico, and Borneo reveal a first-order linear relationship between the depth to the top and base of gas hydrate occurrence. The reason for these nearly linear relationships is believed to be the strong pressure and temperature dependence of methane solubility in the absence of large difference in thermal gradients between the various sites assessed. In addition, a statistically robust relationship was defined between the thickness of the gas hydrate occurrence zone and the base of gas hydrate stability (in meters below seafloor). The relationship developed is able to predict the depth of the top of gas hydrate occurrence zone using observed depths of the base of gas hydrate stability within less than 50 m at most locations examined in this study. No clear correlation of the depth to the top and base of gas hydrate occurrences with geothermal gradient and sulfate-methane transition depth was identified.

  4. Breathing of Graphite Particles in a Lithium-Ion Battery

    NASA Astrophysics Data System (ADS)

    Takata, Keiji; Okuda, Mitsuhiro; Yura, Nobuki; Tamura, Ryota

    2012-04-01

    We imaged changes in volume of graphite particles in a Li-ion battery due to the insertion and extraction of Li ions using scanning probe microscopy. When Li ions were extracted from the graphite particles, the particles were contracted, while expansion was induced in the interspaces between the particles. Variations of the images of volume changes depending on modulation frequencies clearly showed lithium intercalation. A linear relationship between the amplitudes of volume changes and the products of the diffusion elements and the reciprocals of the frequencies has been proven. Thus, the detected signals quantitatively well corresponded to the lithium ion movements.

  5. A Statistical Analysis of the Solar Phenomena Associated with Global EUV Waves

    NASA Astrophysics Data System (ADS)

    Long, D. M.; Murphy, P.; Graham, G.; Carley, E. P.; Pérez-Suárez, D.

    2017-12-01

    Solar eruptions are the most spectacular events in our solar system and are associated with many different signatures of energy release including solar flares, coronal mass ejections, global waves, radio emission and accelerated particles. Here, we apply the Coronal Pulse Identification and Tracking Algorithm (CorPITA) to the high-cadence synoptic data provided by the Solar Dynamics Observatory (SDO) to identify and track global waves observed by SDO. 164 of the 362 solar flare events studied (45%) were found to have associated global waves with no waves found for the remaining 198 (55%). A clear linear relationship was found between the median initial velocity and the acceleration of the waves, with faster waves exhibiting a stronger deceleration (consistent with previous results). No clear relationship was found between global waves and type II radio bursts, electrons or protons detected in situ near Earth. While no relationship was found between the wave properties and the associated flare size (with waves produced by flares from B to X-class), more than a quarter of the active regions studied were found to produce more than one wave event. These results suggest that the presence of a global wave in a solar eruption is most likely determined by the structure and connectivity of the erupting active region and the surrounding quiet solar corona rather than by the amount of free energy available within the active region.

  6. Dose-Response for Multiple Biomarkers of Exposure and Genotoxic Effect Following Repeated Treatment of Rats with the Alkylating Agents, MMS and MNU.

    PubMed

    Ji, Zhiying; LeBaron, Matthew J; Schisler, Melissa R; Zhang, Fagen; Bartels, Michael J; Gollapudi, B Bhaskar; Pottenger, Lynn H

    2016-05-01

    The nature of the dose-response relationship for various in vivo endpoints of exposure and effect were investigated using the alkylating agents, methyl methanesulfonate (MMS) and methylnitrosourea (MNU). Six male F344 rats/group were dosed orally with 0, 0.5, 1, 5, 25 or 50mg/kg bw/day (mkd) of MMS, or 0, 0.01, 0.1, 1, 5, 10, 25 or 50 mkd of MNU, for 4 consecutive days and sacrificed 24h after the last dose. The dose-responses for multiple biomarkers of exposure and genotoxic effect were investigated. In MMS-treated rats, the hemoglobin adduct level, a systemic exposure biomarker, increased linearly with dose (r (2) = 0.9990, P < 0.05), indicating the systemic availability of MMS; however, the N7MeG DNA adduct, a target exposure biomarker, exhibited a non-linear dose-response in blood and liver tissues. Blood reticulocyte micronuclei (MN), a genotoxic effect biomarker, exhibited a clear no-observed-genotoxic-effect-level (NOGEL) of 5 mkd as a point of departure (PoD) for MMS. Two separate dose-response models, the Lutz and Lutz model and the stepwise approach using PROC REG both supported a bilinear/threshold dose-response for MN induction. Liver gene expression, a mechanistic endpoint, also exhibited a bilinear dose-response. Similarly, in MNU-treated rats, hepatic DNA adducts, gene expression changes and MN all exhibited clear PoDs, with a NOGEL of 1 mkd for MN induction, although dose-response modeling of the MNU-induced MN data showed a better statistical fit for a linear dose-response. In summary, these results provide in vivo data that support the existence of clear non-linear dose-responses for a number of biologically significant events along the pathway for genotoxicity induced by DNA-reactive agents. © The Author 2015. Published by Oxford University Press on behalf of the UK Environmental Mutagen Society. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  7. Correlation of the seasonal isotopic amplitude of precipitation with annual evaporation and altitude in alpine regions.

    PubMed

    Jódar, J; Custodio, E; Liotta, M; Lambán, L J; Herrera, C; Martos-Rosillo, S; Sapriza, G; Rigo, T

    2016-04-15

    The time series of stable water isotope composition relative to IAEA-GNIP meteorological stations located in alpine zones are analyzed in order to study how the amplitude of the seasonal isotopic composition of precipitation (Aδ) varies along a vertical transect. A clear relationship between Aδ and local evaporation is obtained, with slopes of -0.87 ‰/100mm/yr and -7.3 ‰/100mm/yr for Aδ(18)O and Aδ(2)H, respectively. When all sampling points of the vertical transect receive the same moisture sources, then a linear relationship between Aδ and elevation is obtained, with vertical gradients of 0.16 ‰/100mm/yr and 1.46 ‰/100mm/yr forAδ(18)O and Aδ(2)H, respectively. Copyright © 2015. Published by Elsevier B.V.

  8. Racially diverse classrooms: effects of classroom racial composition on interracial peer relationships.

    PubMed

    Barth, Joan M; McDonald, Kristina L; Lochman, John E; Boxmeyer, Carolyn; Powell, Nicole; Dillon, Casey; Sallee, Meghann

    2013-01-01

    The purpose of this study was to examine the interactive effects that a child's race and the racial composition of a classroom have on a variety of sociometric measures. Sociometric nominations were collected from 872 fifth-grade students (48% male, 48% Black) who were in classrooms that ranged from nearly all Black to nearly all White students. Hierarchical Linear Modeling analyses indicated that the race of the child, the race of the rater, and the classroom race composition each impacted sociometric nominations. Results suggest that schools that are more balanced in the distribution of Black and White students might promote more positive interracial peer relationships. However, opportunities to be highly liked and to be perceived as a leader might be greatest in a school in which the child is in the clear racial majority. © 2013 American Orthopsychiatric Association.

  9. Modelling daily water temperature from air temperature for the Missouri River.

    PubMed

    Zhu, Senlin; Nyarko, Emmanuel Karlo; Hadzima-Nyarko, Marijana

    2018-01-01

    The bio-chemical and physical characteristics of a river are directly affected by water temperature, which thereby affects the overall health of aquatic ecosystems. It is a complex problem to accurately estimate water temperature. Modelling of river water temperature is usually based on a suitable mathematical model and field measurements of various atmospheric factors. In this article, the air-water temperature relationship of the Missouri River is investigated by developing three different machine learning models (Artificial Neural Network (ANN), Gaussian Process Regression (GPR), and Bootstrap Aggregated Decision Trees (BA-DT)). Standard models (linear regression, non-linear regression, and stochastic models) are also developed and compared to machine learning models. Analyzing the three standard models, the stochastic model clearly outperforms the standard linear model and nonlinear model. All the three machine learning models have comparable results and outperform the stochastic model, with GPR having slightly better results for stations No. 2 and 3, while BA-DT has slightly better results for station No. 1. The machine learning models are very effective tools which can be used for the prediction of daily river temperature.

  10. Self-reported smoking, serum cotinine, and blood DNA methylation.

    PubMed

    Zhang, Yan; Florath, Ines; Saum, Kai-Uwe; Brenner, Hermann

    2016-04-01

    Epigenome-wide profiling of DNA methylation pattern with respect to tobacco smoking has given rise to a new measure of smoking exposure. We investigated the relationships of methylation markers with both cotinine, an established marker of internal smoking exposure, and self-reported smoking. Blood DNA methylation levels across the genome and serum cotinine were measured in 1000 older adults aged 50-75 years. Epigenome-wide scans were performed to identify methylation markers associated with cotinine. The inter-dose-response relationships between the number of cigarettes smoked per day, cotinine concentration, and DNA methylation were modeled by restricted cubic spline regression. Of 61 CpGs that passed the genome-wide significance threshold (p<1.13×10(-7)), 40 CpGs in 25 chromosomal regions were successfully replicated, showing 0.2-3% demethylation per 10ng/ml increases in cotinine. The strongest associations were observed for several loci at AHRR, F2RL3, 2q37.1, 6p21.33, and GFI1 that were previously identified to be related to self-reported smoking. One locus at RAB34 was newly discovered. Both cotinine and methylation markers exhibited non-linear relationships with the number of cigarettes smoked per day, where the highest rates of increase in cotinine and decreases in methylation were observed at low smoking intensity (1-15 cigarettes/day) and plateaued at high smoking intensity (>15-20 cigarettes/day). A clear linear relationship was observed between cotinine concentration and methylation level. Both cotinine and methylation markers showed similar accuracy in distinguishing current from never smoker, but only methylation markers distinguished former from never smoker with high accuracy. Our study corroborates and expands the list of smoking-associated DNA methylation markers. Methylation levels were linearly related to cotinine concentration and provided accurate measures for both current and past smoking exposure. Copyright © 2016 Elsevier Inc. All rights reserved.

  11. Are Successive Investments in Education Equally Worthwhile? Endogenous Schooling Decisions and Non-Linearities in the Earnings-Schooling Relationship

    ERIC Educational Resources Information Center

    Skalli, Ali

    2007-01-01

    Most of the studies that account for the endogeneity bias when estimating the returns to schooling assume that the relationship between education and earnings is linear. Studies that assume the latter relationship to be non-linear simply ignore the endogeneity bias. Moreover, they either assume an ad-hoc non-linear relationship or argue that…

  12. An application of change-point recursive models to the relationship between litter size and number of stillborns in pigs.

    PubMed

    Ibáñez-Escriche, N; López de Maturana, E; Noguera, J L; Varona, L

    2010-11-01

    We developed and implemented change-point recursive models and compared them with a linear recursive model and a standard mixed model (SMM), in the scope of the relationship between litter size (LS) and number of stillborns (NSB) in pigs. The proposed approach allows us to estimate the point of change in multiple-segment modeling of a nonlinear relationship between phenotypes. We applied the procedure to a data set provided by a commercial Large White selection nucleus. The data file consisted of LS and NSB records of 4,462 parities. The results of the analysis clearly identified the location of the change points between different structural regression coefficients. The magnitude of these coefficients increased with LS, indicating an increasing incidence of LS on the NSB ratio. However, posterior distributions of correlations were similar across subpopulations (defined by the change points on LS), except for those between residuals. The heritability estimates of NSB did not present differences between recursive models. Nevertheless, these heritabilities were greater than those obtained for SMM (0.05) with a posterior probability of 85%. These results suggest a nonlinear relationship between LS and NSB, which supports the adequacy of a change-point recursive model for its analysis. Furthermore, the results from model comparisons support the use of recursive models. However, the adequacy of the different recursive models depended on the criteria used: the linear recursive model was preferred on account of its smallest deviance value, whereas nonlinear recursive models provided a better fit and predictive ability based on the cross-validation approach.

  13. Old and New Ideas for Data Screening and Assumption Testing for Exploratory and Confirmatory Factor Analysis

    PubMed Central

    Flora, David B.; LaBrish, Cathy; Chalmers, R. Philip

    2011-01-01

    We provide a basic review of the data screening and assumption testing issues relevant to exploratory and confirmatory factor analysis along with practical advice for conducting analyses that are sensitive to these concerns. Historically, factor analysis was developed for explaining the relationships among many continuous test scores, which led to the expression of the common factor model as a multivariate linear regression model with observed, continuous variables serving as dependent variables, and unobserved factors as the independent, explanatory variables. Thus, we begin our paper with a review of the assumptions for the common factor model and data screening issues as they pertain to the factor analysis of continuous observed variables. In particular, we describe how principles from regression diagnostics also apply to factor analysis. Next, because modern applications of factor analysis frequently involve the analysis of the individual items from a single test or questionnaire, an important focus of this paper is the factor analysis of items. Although the traditional linear factor model is well-suited to the analysis of continuously distributed variables, commonly used item types, including Likert-type items, almost always produce dichotomous or ordered categorical variables. We describe how relationships among such items are often not well described by product-moment correlations, which has clear ramifications for the traditional linear factor analysis. An alternative, non-linear factor analysis using polychoric correlations has become more readily available to applied researchers and thus more popular. Consequently, we also review the assumptions and data-screening issues involved in this method. Throughout the paper, we demonstrate these procedures using an historic data set of nine cognitive ability variables. PMID:22403561

  14. On a report that the 2012 M 6.0 earthquake in Italy was predicted after seeing an unusual cloud formation

    USGS Publications Warehouse

    Thomas, J.N.; Masci, F; Love, Jeffrey J.

    2015-01-01

    Several recently published reports have suggested that semi-stationary linear-cloud formations might be causally precursory to earthquakes. We examine the report of Guangmeng and Jie (2013), who claim to have predicted the 2012 M 6.0 earthquake in the Po Valley of northern Italy after seeing a satellite photograph (a digital image) showing a linear-cloud formation over the eastern Apennine Mountains of central Italy. From inspection of 4 years of satellite images we find numerous examples of linear-cloud formations over Italy. A simple test shows no obvious statistical relationship between the occurrence of these cloud formations and earthquakes that occurred in and around Italy. All of the linear-cloud formations we have identified in satellite images, including that which Guangmeng and Jie (2013) claim to have used to predict the 2012 earthquake, appear to be orographic – formed by the interaction of moisture-laden wind flowing over mountains. Guangmeng and Jie (2013) have not clearly stated how linear-cloud formations can be used to predict the size, location, and time of an earthquake, and they have not published an account of all of their predictions (including any unsuccessful predictions). We are skeptical of the validity of the claim by Guangmeng and Jie (2013) that they have managed to predict any earthquakes.

  15. Relationship Between Maximum Tsunami Amplitude and Duration of Signal

    NASA Astrophysics Data System (ADS)

    Kim, Yoo Yin; Whitmore, Paul M.

    2014-12-01

    All available tsunami observations at tide gauges situated along the North American coast were examined to determine if there is any clear relationship between maximum amplitude and signal duration. In total, 89 historical tsunami recordings generated by 13 major earthquakes between 1952 and 2011 were investigated. Tidal variations were filtered out of the signal and the duration between the arrival time and the time at which the signals drops and stays below 0.3 m amplitude was computed. The processed tsunami time series were evaluated and a linear least-squares fit with a 95 % confidence interval was examined to compare tsunami durations with maximum tsunami amplitude in the study region. The confidence interval is roughly 20 h over the range of maximum tsunami amplitudes in which we are interested. This relatively large confidence interval likely results from variations in local resonance effects, late-arriving reflections, and other effects.

  16. The relationship between peak velocity of saccadic eye movements and serum benzodiazepine concentration.

    PubMed Central

    Bittencourt, P R; Wade, P; Smith, A T; Richens, A

    1981-01-01

    1 Six healthy male volunteers received single oral doses of 10 mg diazepam, 20 mg temazepam, 15 mg flurazepam, 5 mg nitrazepam, 10 mg desmethyl-diazepam and placebo in a double-blind randomized fashion. 2 Peak velocity of saccadic eye movements, serum benzodiazepine concentration, and subjective ratings of wakefulness and co-ordination were measured at intervals up to 12 h after drug administration. 3 All active treatments produced a statistically significant decrease in peak saccadic velocity. The effect of temazepam and diazepam was generally more pronounced than that of flurazepam, nitrazepam and desmethyl-diazepam. 4 There were log-linear correlations between peak saccadic velocity and serum benzodiazepine concentration after ingestion of temazepam, diazepam and nitrazepam. 5 These results demonstrate a clear relationship between serum benzodiazepine concentration and its effect on a convenient measure of brainstem reticular formation function. PMID:6794587

  17. Formation of aldehydes and carboxylic acids in ozonated surface water and wastewater: a clear relationship with fluorescence changes.

    PubMed

    Liu, Chen; Tang, Xiangyu; Kim, Jaeshin; Korshin, Gregory V

    2015-04-01

    This study examined the formation of aldehydes and carboxylic acids in ozonated surface water and municipal wastewater secondary effluent and addressed correlations between the generation of these compounds and concurrent changes of the fluorescence of natural/effluent organic matter (NOM/EfOM) substrates. Ozonation was effective in removing fluorophores in all excitation/emission matrix (EEM) regions, with those operationally assigned to humic- and protein-like species showing relatively higher reactivity than fulvic-like species. Examination of HO exposures and attendant changes of fluorescence-based parameters allows establishing strong linear relationships between formation of the aldehydes and carboxylic acids and the relative changes of integrated fluorescence (ΔIF/IF0). This demonstrates the feasibility of surrogate monitoring of the formation of biodegradable ozonation by-products via online measurements of water/wastewater EEM fluorescence. Copyright © 2014 Elsevier Ltd. All rights reserved.

  18. The mediating role of dietary factors and leisure time physical activity on socioeconomic inequalities in body mass index among Australian adults.

    PubMed

    Gearon, Emma; Backholer, Kathryn; Hodge, Allison; Peeters, Anna

    2013-12-21

    The relationship between socioeconomic position and obesity has been clearly established, however, the extent to which specific behavioural factors mediate this relationship is less clear. This study aimed to ascertain the contribution of specific dietary elements and leisure-time physical activity (LTPA) to variations in obesity with education in the baseline (1990-1994) Melbourne Collaborative Cohort Study (MCCS). 18, 489 women and 12, 141 men were included in this cross-sectional analysis. A series of linear regression models were used in accordance with the products of coefficients method to examine the mediating role of alcohol, soft drink (regular and diet), snacks (healthy and sweet), savoury items (healthy and unhealthy), meeting fruit and vegetable guidelines and LTPA on the relationship between education and body mass index (BMI). Compared to those with lowest educational attainment, those with the highest educational attainment had a 1 kg/m2 lower BMI. Among men and women, 27% and 48%, respectively, of this disparity was attributable to differences in LTPA and diet. Unhealthy savoury item consumption and LTPA contributed most to the mediated effects for men and women. Alcohol and diet soft drink were additionally important mediators for women. Diet and LTPA are potentially modifiable behavioural risk factors for the development of obesity that contribute substantially to inequalities in BMI. Our findings highlight the importance of specific behaviours which may be useful to the implementation of effective, targeted public policy to reduce socioeconomic inequalities in obesity.

  19. Reducing bias and analyzing variability in the time-left procedure.

    PubMed

    Trujano, R Emmanuel; Orduña, Vladimir

    2015-04-01

    The time-left procedure was designed to evaluate the psychophysical function for time. Although previous results indicated a linear relationship, it is not clear what role the observed bias toward the time-left option plays in this procedure and there are no reports of how variability changes with predicted indifference. The purposes of this experiment were to reduce bias experimentally, and to contrast the difference limen (a measure of variability around indifference) with predictions from scalar expectancy theory (linear timing) and behavioral economic model (logarithmic timing). A control group of 6 rats performed the original time-left procedure with C=60 s and S=5, 10,…, 50, 55 s, whereas a no-bias group of 6 rats performed the same conditions in a modified time-left procedure in which only a single response per choice trial was allowed. Results showed that bias was reduced for the no-bias group, observed indifference grew linearly with predicted indifference for both groups, and difference limen and Weber ratios decreased as expected indifference increased for the control group, which is consistent with linear timing, whereas for the no-bias group they remained constant, consistent with logarithmic timing. Therefore, the time-left procedure generates results consistent with logarithmic perceived time once bias is experimentally reduced. Copyright © 2015 Elsevier B.V. All rights reserved.

  20. Worldwide variations in artificial skyglow

    PubMed Central

    Kyba, Christopher C. M.; Tong, Kai Pong; Bennie, Jonathan; Birriel, Ignacio; Birriel, Jennifer J.; Cool, Andrew; Danielsen, Arne; Davies, Thomas W.; Outer, Peter N. den; Edwards, William; Ehlert, Rainer; Falchi, Fabio; Fischer, Jürgen; Giacomelli, Andrea; Giubbilini, Francesco; Haaima, Marty; Hesse, Claudia; Heygster, Georg; Hölker, Franz; Inger, Richard; Jensen, Linsey J.; Kuechly, Helga U.; Kuehn, John; Langill, Phil; Lolkema, Dorien E.; Nagy, Matthew; Nievas, Miguel; Ochi, Nobuaki; Popow, Emil; Posch, Thomas; Puschnig, Johannes; Ruhtz, Thomas; Schmidt, Wim; Schwarz, Robert; Schwope, Axel; Spoelstra, Henk; Tekatch, Anthony; Trueblood, Mark; Walker, Constance E.; Weber, Michael; Welch, Douglas L.; Zamorano, Jaime; Gaston, Kevin J.

    2015-01-01

    Despite constituting a widespread and significant environmental change, understanding of artificial nighttime skyglow is extremely limited. Until now, published monitoring studies have been local or regional in scope, and typically of short duration. In this first major international compilation of monitoring data we answer several key questions about skyglow properties. Skyglow is observed to vary over four orders of magnitude, a range hundreds of times larger than was the case before artificial light. Nearly all of the study sites were polluted by artificial light. A non-linear relationship is observed between the sky brightness on clear and overcast nights, with a change in behavior near the rural to urban landuse transition. Overcast skies ranged from a third darker to almost 18 times brighter than clear. Clear sky radiances estimated by the World Atlas of Artificial Night Sky Brightness were found to be overestimated by ~25%; our dataset will play an important role in the calibration and ground truthing of future skyglow models. Most of the brightly lit sites darkened as the night progressed, typically by ~5% per hour. The great variation in skyglow radiance observed from site-to-site and with changing meteorological conditions underlines the need for a long-term international monitoring program. PMID:25673335

  1. Spectral Invariant Behavior of Zenith Radiance Around Cloud Edges Observed by ARM SWS

    NASA Technical Reports Server (NTRS)

    Marshak, A.; Knyazikhin, Y.; Chiu, J. C.; Wiscombe, W. J.

    2009-01-01

    The ARM Shortwave Spectrometer (SWS) measures zenith radiance at 418 wavelengths between 350 and 2170 nm. Because of its 1-sec sampling resolution, the SWS provides a unique capability to study the transition zone between cloudy and clear sky areas. A spectral invariant behavior is found between ratios of zenith radiance spectra during the transition from cloudy to cloud-free. This behavior suggests that the spectral signature of the transition zone is a linear mixture between the two extremes (definitely cloudy and definitely clear). The weighting function of the linear mixture is a wavelength-independent characteristic of the transition zone. It is shown that the transition zone spectrum is fully determined by this function and zenith radiance spectra of clear and cloudy regions. An important result of these discoveries is that high temporal resolution radiance measurements in the clear-to-cloud transition zone can be well approximated by lower temporal resolution measurements plus linear interpolation.

  2. Linear separability in superordinate natural language concepts.

    PubMed

    Ruts, Wim; Storms, Gert; Hampton, James

    2004-01-01

    Two experiments are reported in which linear separability was investigated in superordinate natural language concept pairs (e.g., toiletry-sewing gear). Representations of the exemplars of semantically related concept pairs were derived in two to five dimensions using multidimensional scaling (MDS) of similarities based on possession of the concept features. Next, category membership, obtained from an exemplar generation study (in Experiment 1) and from a forced-choice classification task (in Experiment 2) was predicted from the coordinates of the MDS representation using log linear analysis. The results showed that all natural kind concept pairs were perfectly linearly separable, whereas artifact concept pairs showed several violations. Clear linear separability of natural language concept pairs is in line with independent cue models. The violations in the artifact pairs, however, yield clear evidence against the independent cue models.

  3. Match statistics related to winning in the group stage of 2014 Brazil FIFA World Cup.

    PubMed

    Liu, Hongyou; Gomez, Miguel-Ángel; Lago-Peñas, Carlos; Sampaio, Jaime

    2015-01-01

    Identifying match statistics that strongly contribute to winning in football matches is a very important step towards a more predictive and prescriptive performance analysis. The current study aimed to determine relationships between 24 match statistics and the match outcome (win, loss and draw) in all games and close games of the group stage of FIFA World Cup (2014, Brazil) by employing the generalised linear model. The cumulative logistic regression was run in the model taking the value of each match statistic as independent variable to predict the logarithm of the odds of winning. Relationships were assessed as effects of a two-standard-deviation increase in the value of each variable on the change in the probability of a team winning a match. Non-clinical magnitude-based inferences were employed and were evaluated by using the smallest worthwhile change. Results showed that for all the games, nine match statistics had clearly positive effects on the probability of winning (Shot, Shot on Target, Shot from Counter Attack, Shot from Inside Area, Ball Possession, Short Pass, Average Pass Streak, Aerial Advantage and Tackle), four had clearly negative effects (Shot Blocked, Cross, Dribble and Red Card), other 12 statistics had either trivial or unclear effects. While for the close games, the effects of Aerial Advantage and Yellow Card turned to trivial and clearly negative, respectively. Information from the tactical modelling can provide a more thorough and objective match understanding to coaches and performance analysts for evaluating post-match performances and for scouting upcoming oppositions.

  4. Alternative method for quantification of alfa-amylase activity.

    PubMed

    Farias, D F; Carvalho, A F U; Oliveira, C C; Sousa, N M; Rocha-Bezerrra, L C B; Ferreira, P M P; Lima, G P G; Hissa, D C

    2010-05-01

    A modification of the sensitive agar diffusion method was developed for macro-scale determination of alfa-amylase. The proposed modifications lower costs with the utilisation of starch as substrate and agar as supporting medium. Thus, a standard curve was built using alfa-amylase solution from Aspergillus oryzae, with concentrations ranging from 2.4 to 7,500 U.mL-1. Clear radial diffusion zones were measured after 4 hours of incubation at 20 A degrees C. A linear relationship between the logarithm of enzyme activities and the area of clear zones was obtained. The method was validated by testing alpha-amylase from barley at the concentrations of 2.4; 60; 300 and 1,500 U.mL-1. The proposed method turned out to be simpler, faster, less expensive and able to determine on a macro-scale alpha-amylase over a wide range (2.4 to 7,500 U.mL-1) in scientific investigation as well as in teaching laboratory activities.

  5. Do quality indicators for general practice teaching practices predict good outcomes for students?

    PubMed

    Bartlett, Maggie; Potts, Jessica; McKinley, Bob

    2016-07-01

    Keele medical students spend 113 days in general practices over our five-year programme. We collect practice data thought to indicate good quality teaching. We explored the relationships between these data and two outcomes for students; Objective Structured Clinical Examination (OSCE) scores and feedback regarding the placements. Though both are surrogate markers of good teaching, they are widely used. We collated practice and outcome data for one academic year. Two separate statistical analyses were carried out: (1) to determine how much of the variation seen in the OSCE scores was due to the effect of the practice and how much to the individual student. (2) to identify practice characteristics with a relationship to student feedback scores. (1) OSCE performance: 268 students in 90 practices: six quality indicators independently influenced the OSCE score, though without linear relationships and not to statistical significance. (2) Student satisfaction: 144 students in 69 practices: student feedback scores are not influenced by practice characteristics. The relationships between the quality indicators we collect for practices and outcomes for students are not clear. It may be that neither the quality indicators nor the outcome measures are reliable enough to inform decisions about practices' suitability for teaching.

  6. On modelling the relationship between vegetation greenness and water balance and land use change.

    PubMed

    Berry, Sandra L; Mackey, Brendan

    2018-06-13

    Here we sought a biologically meaningful, climate variable that captures water-energy availability and is suitable for high resolution (250 m × 250 m) modelling of the fraction of photosynthetically active radiation intercepted by the sunlit canopy (F V ) derived from a 10-year (July 2000 - June 2010) time series of Moderate Resolution Imaging Spectroradiometer (MODIS) Normalized difference vegetation index (NDVI) satellite imagery for Australia. The long-term mean annual evaporation deficit, and mean annual water availability indices all yielded strong linear relationships with mean F V ([Formula: see text], %). We hypothesised whether some of the scatter about the relationships was related to land-use changes that have disrupted the vegetation-climate-soil equilibrium. Using continental-scale spatial data layers of protected area status and vegetation condition classes we repeated our analyses with restricted datasets. [Formula: see text] of intact native vegetation within protected areas was greater than all modified vegetation classes. There was a consistent decline in the slopes of the regression relationships with increasing intensity of woody vegetation clearing and livestock grazing. Where native vegetation has been transformed by land use there was a 25% reduction in predicted [Formula: see text].

  7. Natural canopy bridges effectively mitigate tropical forest fragmentation for arboreal mammals.

    PubMed

    Gregory, Tremaine; Carrasco-Rueda, Farah; Alonso, Alfonso; Kolowski, Joseph; Deichmann, Jessica L

    2017-06-20

    Linear infrastructure development and resulting habitat fragmentation are expanding in Neotropical forests, and arboreal mammals may be disproportionately impacted by these linear habitat clearings. Maintaining canopy connectivity through preservation of connecting branches (i.e. natural canopy bridges) may help mitigate that impact. Using camera traps, we evaluated crossing rates of a pipeline right-of-way in a control area with no bridges and in a test area where 13 bridges were left by the pipeline construction company. Monitoring all canopy crossing points for a year (7,102 canopy camera nights), we confirmed bridge use by 25 mammal species from 12 families. With bridge use beginning immediately after exposure and increasing over time, use rates were over two orders of magnitude higher than on the ground. We also found a positive relationship between a bridge's use rate and the number of species that used it, suggesting well-used bridges benefit multiple species. Data suggest bridge use may be related to a combination of bridge branch connectivity, multiple connections, connectivity to adjacent forest, and foliage cover. Given the high use rate and minimal cost, we recommend all linear infrastructure projects in forests with arboreal mammal populations include canopy bridges.

  8. Impact of ENSO longitudinal position on teleconnections to the NAO

    NASA Astrophysics Data System (ADS)

    Zhang, Wenjun; Wang, Ziqi; Stuecker, Malte F.; Turner, Andrew G.; Jin, Fei-Fei; Geng, Xin

    2018-02-01

    While significant improvements have been made in understanding how the El Niño-Southern Oscillation (ENSO) impacts both North American and Asian climate, its relationship with the North Atlantic Oscillation (NAO) remains less clear. Observations indicate that ENSO exhibits a highly complex relationship with the NAO-associated atmospheric circulation. One critical contribution to this ambiguous ENSO/NAO relationship originates from ENSO's diversity in its spatial structure. In general, both eastern (EP) and central Pacific (CP) El Niño events tend to be accompanied by a negative NAO-like atmospheric response. However, for two different types of La Niña the NAO response is almost opposite. Thus, the NAO responses for the CP ENSO are mostly linear, while nonlinear NAO responses dominate for the EP ENSO. These contrasting extra-tropical atmospheric responses are mainly attributed to nonlinear air-sea interactions in the tropical eastern Pacific. The local atmospheric response to the CP ENSO sea surface temperature (SST) anomalies is highly linear since the air-sea action center is located within the Pacific warm pool, characterized by relatively high climatological SSTs. In contrast, the EP ENSO SST anomalies are located in an area of relatively low climatological SSTs in the eastern equatorial Pacific. Here only sufficiently high positive SST anomalies during EP El Niño events are able to overcome the SST threshold for deep convection, while hardly any anomalous convection is associated with EP La Niña SSTs that are below this threshold. This ENSO/NAO relationship has important implications for NAO seasonal prediction and places a higher requirement on models in reproducing the full diversity of ENSO.

  9. Is More Always Better? The Curvilinear Relationships between College Student Experiences and Outcomes

    ERIC Educational Resources Information Center

    Bowman, Nicholas A.; Trolian, Teniell L.

    2017-01-01

    Many higher education studies have examined linear relationships between student experiences and outcomes, but this assumption may be questionable. In two notable examples previous research that assumed a linear relationship reached different substantive conclusions and implications than did research that explored non-linear associations among the…

  10. Routine activities and victimization at school: the significance of gender.

    PubMed

    Popp, Ann Marie; Peguero, Anthony A

    2011-08-01

    Routine activities theory has not fully considered the role of gender in shaping victimization and yet, the research literature clearly demonstrates that gender is associated with an individual's risk of victimization. In addition to the pervasive effect of gender on victimization, gender shapes an individual's daily routines and thus may create a gender-specific relationship with victimization. This article explores the importance of gender in understanding the relationship between student's participation in extracurricular routine activities (e.g., student government, clubs, sports, and etc.) and the risk of victimization. From the Education Longitudinal Study of 2002, a sample of 10th-grade students was drawn for analyses. Hierarchical Generalized Linear Modeling was employed to explore the role of gender in the relationship between extracurricular routine activities and victimization at school. The results reveal that students' gender indeed interacts with several of the extracurricular routine activities creating gender-specific risks of victimization. This article highlights the importance of gender in explaining victimization and suggests researchers should consider how gender may interact with other routine activities and victimization.

  11. Relationship between energy deposition and shock wave phenomenon in an underwater electrical wire explosion

    NASA Astrophysics Data System (ADS)

    Han, Ruoyu; Zhou, Haibin; Wu, Jiawei; Qiu, Aici; Ding, Weidong; Zhang, Yongmin

    2017-09-01

    An experimental study of pressure waves generated by an exploding copper wire in a water medium is performed. We examined the effects of energy deposited at different stages on the characteristics of the resulting shock waves. In the experiments, a microsecond time-scale pulsed current source was used to explode a 300-μm-diameter, 4-cm-long copper wire with initial stored energies ranging from 500 to 2700 J. Our experimental results indicated that the peak pressure (4.5-8.1 MPa) and energy (49-287 J) of the shock waves did not follow a simple relationship with any electrical parameters, such as peak voltage or deposited energy. Conversely, the impulse had a quasi-linear relationship with the parameter Π. We also found that the peak pressure was mainly influenced by the energy deposited before separation of the shock wave front and the discharge plasma channel (DPC). The decay time constant of the pressure waveform was affected by the energy injection after the separation. These phenomena clearly demonstrated that the deposited energy influenced the expansion of the DPC and affected the shock wave characteristics.

  12. Fluorescent scanning x-ray tomography with synchrotron radiation

    NASA Astrophysics Data System (ADS)

    Takeda, Tohoru; Maeda, Toshikazu; Yuasa, Tetsuya; Akatsuka, Takao; Ito, Tatsuo; Kishi, Kenichi; Wu, Jin; Kazama, Masahiro; Hyodo, Kazuyuki; Itai, Yuji

    1995-02-01

    Fluorescent scanning (FS) x-ray tomography was developed to detect nonradioactive tracer materials (iodine and gadolinium) in a living object. FS x-ray tomography consists of a silicon (111) channel cut monochromator, an x-ray shutter, an x-ray slit system and a collimator for detection, a scanning table for the target organ, and an x-ray detector with pure germanium. The minimal detectable dose of iodine in this experiment was 100 ng in a volume of 2 mm3 and a linear relationship was shown between the photon counts of a fluorescent x ray and the concentration of iodine contrast material. A FS x-ray tomographic image was clearly obtained with a phantom.

  13. Expanding the occupational health methodology: A concatenated artificial neural network approach to model the burnout process in Chinese nurses.

    PubMed

    Ladstätter, Felix; Garrosa, Eva; Moreno-Jiménez, Bernardo; Ponsoda, Vicente; Reales Aviles, José Manuel; Dai, Junming

    2016-01-01

    Artificial neural networks are sophisticated modelling and prediction tools capable of extracting complex, non-linear relationships between predictor (input) and predicted (output) variables. This study explores this capacity by modelling non-linearities in the hardiness-modulated burnout process with a neural network. Specifically, two multi-layer feed-forward artificial neural networks are concatenated in an attempt to model the composite non-linear burnout process. Sensitivity analysis, a Monte Carlo-based global simulation technique, is then utilised to examine the first-order effects of the predictor variables on the burnout sub-dimensions and consequences. Results show that (1) this concatenated artificial neural network approach is feasible to model the burnout process, (2) sensitivity analysis is a prolific method to study the relative importance of predictor variables and (3) the relationships among variables involved in the development of burnout and its consequences are to different degrees non-linear. Many relationships among variables (e.g., stressors and strains) are not linear, yet researchers use linear methods such as Pearson correlation or linear regression to analyse these relationships. Artificial neural network analysis is an innovative method to analyse non-linear relationships and in combination with sensitivity analysis superior to linear methods.

  14. Understanding the relationship between duration of untreated psychosis and outcomes: A statistical perspective.

    PubMed

    Hannigan, Ailish; Bargary, Norma; Kinsella, Anthony; Clarke, Mary

    2017-06-14

    Although the relationships between duration of untreated psychosis (DUP) and outcomes are often assumed to be linear, few studies have explored the functional form of these relationships. The aim of this study is to demonstrate the potential of recent advances in curve fitting approaches (splines) to explore the form of the relationship between DUP and global assessment of functioning (GAF). Curve fitting approaches were used in models to predict change in GAF at long-term follow-up using DUP for a sample of 83 individuals with schizophrenia. The form of the relationship between DUP and GAF was non-linear. Accounting for non-linearity increased the percentage of variance in GAF explained by the model, resulting in better prediction and understanding of the relationship. The relationship between DUP and outcomes may be complex and model fit may be improved by accounting for the form of the relationship. This should be routinely assessed and new statistical approaches for non-linear relationships exploited, if appropriate. © 2017 John Wiley & Sons Australia, Ltd.

  15. Alcohol outlet density and assault: a spatial analysis.

    PubMed

    Livingston, Michael

    2008-04-01

    A large number of studies have found links between alcohol outlet densities and assault rates in local areas. This study tests a variety of specifications of this link, focusing in particular on the possibility of a non-linear relationship. Cross-sectional data on police-recorded assaults during high alcohol hours, liquor outlets and socio-demographic characteristics were obtained for 223 postcodes in Melbourne, Australia. These data were used to construct a series of models testing the nature of the relationship between alcohol outlet density and assault, while controlling for socio-demographic factors and spatial auto-correlation. Four types of relationship were examined: a normal linear relationship between outlet density and assault, a non-linear relationship with potential threshold or saturation densities, a relationship mediated by the socio-economic status of the neighbourhood and a relationship which takes into account the effect of outlets in surrounding neighbourhoods. The model positing non-linear relationships between outlet density and assaults was found to fit the data most effectively. An increasing accelerating effect for the density of hotel (pub) licences was found, suggesting a plausible upper limit for these licences in Melbourne postcodes. The study finds positive relationships between outlet density and assault rates and provides evidence that this relationship is non-linear and thus has critical values at which licensing policy-makers can impose density limits.

  16. Liquid-crystal-based switchable polarizers for sensor protection.

    PubMed

    Wu, C S; Wu, S T

    1995-11-01

    Linear polarizers are generally employed in conjunction with advanced liquid-crystal filters for the protection of human eyes and optical sensors. For detection sensitivity under a no-threat condition to be maximized, the polarizer should remain in a clear state with a minimum insertion loss. When threats are present, it should be quickly switched to function as a linear polarizer with a high extinction ratio. Two types of switchable polarizer for sensor protection are demonstrated. The polarization conversion type exhibits a high optical efficiency in its clear state, a high extinction ratio in the linear polarizer state, and a fast switching speed, except that its field of view is limited to approximately ±10°. In contrast, an improved switchable dichroic polarizer functions effectively over a much wider field of view. However, its extinction ratio and optical efficiency in its clear state are lower than those of the polarization conversion type.

  17. Liquid-crystal-based switchable polarizers for sensor protection

    NASA Astrophysics Data System (ADS)

    Wu, Chiung-Sheng; Wu, Shin-Tson

    1995-11-01

    Linear polarizers are generally employed in conjunction with advanced liquid-crystal filters for the protection of human eyes and optical sensors. For detection sensitivity under a no-threat condition to be maximized, the polarizer should remain in a clear state with a minimum insertion loss. When threats are present, it should be quickly switched to function as a linear polarizer with a high extinction ratio. Two types of switchable polarizer for sensor protection are demonstrated. The polarization conversion type exhibits a high optical efficiency in its clear state, a high extinction ratio in the linear polarizer state, and a fast switching speed, except that its field of view is limited to approximately +/-10 deg In contrast, an improved switchable dichroic polarizer functions effectively over a much wider field of view. However, its extinction ratio and optical efficiency in its clear state are lower than those of the polarization conversion type.

  18. Sun-Induced Chlorophyll Fluorescence, Photosynthesis, and Light Use Efficiency of a Soybean Field from Seasonally Continuous Measurements

    DOE PAGES

    Miao, Guofang; Guan, Kaiyu; Yang, Xi; ...

    2018-01-29

    Recent development of sun-induced chlorophyll fluorescence (SIF) technology is stimulating studies to remotely approximate canopy photosynthesis (measured as gross primary production, GPP). While multiple applications have advanced the empirical relationship between GPP and SIF, mechanistic understanding of this relationship is still limited. GPP:SIF relationship, using the standard light use efficiency framework, is determined by absorbed photosynthetically active radiation (APAR) and the relationship between photosynthetic light use efficiency (LUE) and fluorescence yield (SIF y). While previous studies have found that APAR is the dominant factor of the GPP:SIF relationship, the LUE:SIF y relationship remains unclear. For a better understanding of themore » LUE:SIF y relationship, in this paper we deployed a ground-based system (FluoSpec2), with an eddy-covariance flux tower at a soybean field in the Midwestern U.S. during the 2016 growing season to collect SIF and GPP data simultaneously. With the measurements categorized by plant growth stages, light conditions, and time scales, we confirmed that a strong positive GPP:SIF relationship was dominated by an even stronger linear SIF:APAR relationship. By normalizing both GPP and SIF by APAR, we found that under sunny conditions our soybean field exhibited a clear positive SIF y:APAR relationship and a weak negative LUE:SIF y relationship, opposite to the positive LUE:SIF y relationship reported previously in other ecosystems. Our study provides a first continuous SIF record over multiple growth stages for agricultural systems and reveals a distinctive pattern related to the LUE:SIF y relationship compared with previous work. Finally, the observed positive relationship of SIF y:APAR at the soybean site provides new insights of the previous understanding on the SIF's physiological implications.« less

  19. Sun-Induced Chlorophyll Fluorescence, Photosynthesis, and Light Use Efficiency of a Soybean Field from Seasonally Continuous Measurements

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Miao, Guofang; Guan, Kaiyu; Yang, Xi

    Recent development of sun-induced chlorophyll fluorescence (SIF) technology is stimulating studies to remotely approximate canopy photosynthesis (measured as gross primary production, GPP). While multiple applications have advanced the empirical relationship between GPP and SIF, mechanistic understanding of this relationship is still limited. GPP:SIF relationship, using the standard light use efficiency framework, is determined by absorbed photosynthetically active radiation (APAR) and the relationship between photosynthetic light use efficiency (LUE) and fluorescence yield (SIF y). While previous studies have found that APAR is the dominant factor of the GPP:SIF relationship, the LUE:SIF y relationship remains unclear. For a better understanding of themore » LUE:SIF y relationship, in this paper we deployed a ground-based system (FluoSpec2), with an eddy-covariance flux tower at a soybean field in the Midwestern U.S. during the 2016 growing season to collect SIF and GPP data simultaneously. With the measurements categorized by plant growth stages, light conditions, and time scales, we confirmed that a strong positive GPP:SIF relationship was dominated by an even stronger linear SIF:APAR relationship. By normalizing both GPP and SIF by APAR, we found that under sunny conditions our soybean field exhibited a clear positive SIF y:APAR relationship and a weak negative LUE:SIF y relationship, opposite to the positive LUE:SIF y relationship reported previously in other ecosystems. Our study provides a first continuous SIF record over multiple growth stages for agricultural systems and reveals a distinctive pattern related to the LUE:SIF y relationship compared with previous work. Finally, the observed positive relationship of SIF y:APAR at the soybean site provides new insights of the previous understanding on the SIF's physiological implications.« less

  20. Quantifying feedforward control: a linear scaling model for fingertip forces and object weight.

    PubMed

    Lu, Ying; Bilaloglu, Seda; Aluru, Viswanath; Raghavan, Preeti

    2015-07-01

    The ability to predict the optimal fingertip forces according to object properties before the object is lifted is known as feedforward control, and it is thought to occur due to the formation of internal representations of the object's properties. The control of fingertip forces to objects of different weights has been studied extensively by using a custom-made grip device instrumented with force sensors. Feedforward control is measured by the rate of change of the vertical (load) force before the object is lifted. However, the precise relationship between the rate of change of load force and object weight and how it varies across healthy individuals in a population is not clearly understood. Using sets of 10 different weights, we have shown that there is a log-linear relationship between the fingertip load force rates and weight among neurologically intact individuals. We found that after one practice lift, as the weight increased, the peak load force rate (PLFR) increased by a fixed percentage, and this proportionality was common among the healthy subjects. However, at any given weight, the level of PLFR varied across individuals and was related to the efficiency of the muscles involved in lifting the object, in this case the wrist and finger extensor muscles. These results quantify feedforward control during grasp and lift among healthy individuals and provide new benchmarks to interpret data from neurologically impaired populations as well as a means to assess the effect of interventions on restoration of feedforward control and its relationship to muscular control. Copyright © 2015 the American Physiological Society.

  1. 76 FR 45730 - Customer Clearing Documentation and Timing of Acceptance for Clearing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-01

    ... proposing regulations to facilitate customer access to clearing and to bolster risk management through... and execution of customer transactions on a DCM or SEF on terms that have a reasonable relationship to... a reasonable relationship to the best terms available by prohibiting restrictions in customer...

  2. A Method for Assessing the Quality of Model-Based Estimates of Ground Temperature and Atmospheric Moisture Using Satellite Data

    NASA Technical Reports Server (NTRS)

    Wu, Man Li C.; Schubert, Siegfried; Lin, Ching I.; Stajner, Ivanka; Einaudi, Franco (Technical Monitor)

    2000-01-01

    A method is developed for validating model-based estimates of atmospheric moisture and ground temperature using satellite data. The approach relates errors in estimates of clear-sky longwave fluxes at the top of the Earth-atmosphere system to errors in geophysical parameters. The fluxes include clear-sky outgoing longwave radiation (CLR) and radiative flux in the window region between 8 and 12 microns (RadWn). The approach capitalizes on the availability of satellite estimates of CLR and RadWn and other auxiliary satellite data, and multiple global four-dimensional data assimilation (4-DDA) products. The basic methodology employs off-line forward radiative transfer calculations to generate synthetic clear-sky longwave fluxes from two different 4-DDA data sets. Simple linear regression is used to relate the clear-sky longwave flux discrepancies to discrepancies in ground temperature ((delta)T(sub g)) and broad-layer integrated atmospheric precipitable water ((delta)pw). The slopes of the regression lines define sensitivity parameters which can be exploited to help interpret mismatches between satellite observations and model-based estimates of clear-sky longwave fluxes. For illustration we analyze the discrepancies in the clear-sky longwave fluxes between an early implementation of the Goddard Earth Observing System Data Assimilation System (GEOS2) and a recent operational version of the European Centre for Medium-Range Weather Forecasts data assimilation system. The analysis of the synthetic clear-sky flux data shows that simple linear regression employing (delta)T(sub g)) and broad layer (delta)pw provides a good approximation to the full radiative transfer calculations, typically explaining more thin 90% of the 6 hourly variance in the flux differences. These simple regression relations can be inverted to "retrieve" the errors in the geophysical parameters, Uncertainties (normalized by standard deviation) in the monthly mean retrieved parameters range from 7% for (delta)T(sub g) to approx. 20% for the lower tropospheric moisture between 500 hPa and surface. The regression relationships developed from the synthetic flux data, together with CLR and RadWn observed with the Clouds and Earth Radiant Energy System instrument, ire used to assess the quality of the GEOS2 T(sub g) and pw. Results showed that the GEOS2 T(sub g) is too cold over land, and pw in upper layers is too high over the tropical oceans and too low in the lower atmosphere.

  3. Compositional and physicochemical changes in waste materials and biogas production across 7 landfill sites in UK.

    PubMed

    Frank, R R; Cipullo, S; Garcia, J; Davies, S; Wagland, S T; Villa, R; Trois, C; Coulon, F

    2017-05-01

    The aim of this study was to evaluate the spatial distribution of the paper and fines across seven landfill sites (LFS) and assess the relationship between waste physicochemical properties and biogas production. Physicochemical analysis of the waste samples demonstrated that there were no clear trends in the spatial distribution of total solids (TS), moisture content (MC) and waste organic strength (VS) across all LFS. There was however noticeable difference between samples from the same landfill site. The effect of landfill age on waste physicochemical properties showed no clear relationship, thus, providing evidence that waste remains dormant and non-degraded for long periods of time. Landfill age was however directly correlated with the biochemical methane potential (BMP) of waste; with the highest BMP obtained from the most recent LFS. BMP was also correlated with depth as the average methane production decreased linearly with increasing depth. There was also a high degree of correlation between the Enzymatic Hydrolysis Test (EHT) and BMP test results, which motivates its potential use as an alternative to the BMP test method. Further to this, there were also positive correlations between MC and VS, VS and biogas volume and biogas volume and CH 4 content. Outcomes of this work can be used to inform waste degradation and methane enhancement strategies for improving recovery of methane from landfills. Copyright © 2016 Elsevier Ltd. All rights reserved.

  4. Integrating solar energy and climate research into science education

    NASA Astrophysics Data System (ADS)

    Betts, Alan K.; Hamilton, James; Ligon, Sam; Mahar, Ann Marie

    2016-01-01

    This paper analyzes multi-year records of solar flux and climate data from two solar power sites in Vermont. We show the inter-annual differences of temperature, wind, panel solar flux, electrical power production, and cloud cover. Power production has a linear relation to a dimensionless measure of the transmission of sunlight through the cloud field. The difference between panel and air temperatures reaches 24°C with high solar flux and low wind speed. High panel temperatures that occur in summer with low wind speeds and clear skies can reduce power production by as much as 13%. The intercomparison of two sites 63 km apart shows that while temperature is highly correlated on daily (R2=0.98) and hourly (R2=0.94) timescales, the correlation of panel solar flux drops markedly from daily (R2=0.86) to hourly (R2=0.63) timescales. Minimum temperatures change little with cloud cover, but the diurnal temperature range shows a nearly linear increase with falling cloud cover to 16°C under nearly clear skies, similar to results from the Canadian Prairies. The availability of these new solar and climate datasets allows local student groups, a Rutland High School team here, to explore the coupled relationships between climate, clouds, and renewable power production. As our society makes major changes in our energy infrastructure in response to climate change, it is important that we accelerate the technical education of high school students using real-world data.

  5. The conservative behavior of dissolved organic carbon in surface waters of the southern Chukchi Sea, Arctic Ocean, during early summer

    PubMed Central

    Tanaka, Kazuki; Takesue, Nobuyuki; Nishioka, Jun; Kondo, Yoshiko; Ooki, Atsushi; Kuma, Kenshi; Hirawake, Toru; Yamashita, Youhei

    2016-01-01

    The spatial distribution of dissolved organic carbon (DOC) concentrations and the optical properties of dissolved organic matter (DOM) determined by ultraviolet-visible absorbance and fluorescence spectroscopy were measured in surface waters of the southern Chukchi Sea, western Arctic Ocean, during the early summer of 2013. Neither the DOC concentration nor the optical parameters of the DOM correlated with salinity. Principal component analysis using the DOM optical parameters clearly separated the DOM sources. A significant linear relationship was evident between the DOC and the principal component score for specific water masses, indicating that a high DOC level was related to a terrigenous source, whereas a low DOC level was related to a marine source. Relationships between the DOC and the principal component scores of the surface waters of the southern Chukchi Sea implied that the major factor controlling the distribution of DOC concentrations was the mixing of plural water masses rather than local production and degradation. PMID:27658444

  6. Fetal bovine serum influences the stability and bioactivity of resveratrol analogues: A polyphenol-protein interaction approach.

    PubMed

    Tang, Fen; Xie, Yixi; Cao, Hui; Yang, Hua; Chen, Xiaoqing; Xiao, Jianbo

    2017-03-15

    Fetal bovine serum (FBS) is a universal growth supplement of cell and tissue culture media. Herein, the influences of FBS on the stability and antioxidant activity of 21 resveratrol analogues were investigated using a polyphenol-protein interaction approach. The structure-stability relationships of resveratrol analogues in FBS showed a clear decrease in the stability of hydroxylated resveratrol analogues in the order: resorcinol-type>pyrogallol-type>catechol-type. The glycosylation and methoxylation of resveratrol analogues enhanced their stability. A linear relationship between the stability of resveratrol analogues in FBS and the affinity of resveratrol analogues-FBS interaction was found. The oxidation process is not the only factor governing the stability of resveratrol analogues in FBS. These results facilitated the insightful investigation of the role of polyphenol-protein interactions in serum, thereby providing some fundamental clues for future clinical research and pharmacological studies on natural small molecules. Copyright © 2016 Elsevier Ltd. All rights reserved.

  7. Resilience and risk for alcohol use disorders: A Swedish twin study

    PubMed Central

    Long, E.C.; Lönn, S.L.; Ji, J.; Lichtenstein, P.; Sundquist, J.; Sundquist, K.; Kendler, K.S.

    2016-01-01

    Background Resilience has been shown to be protective against alcohol use disorders (AUD), but the magnitude and nature of the relationship between these two phenotypes is not clear. The aim of this study is to examine the strength of this relationship and the degree to which it results from common genetic or common environmental influences. Methods Resilience was assessed on a nine-point scale during a personal interview in 1,653,721 Swedish men aged 17–25 years. AUD was identified based on Swedish medical, legal, and pharmacy registries. The magnitude of the relationship between resilience and AUD was examined using logistic regression. The extent to which the relationship arises from common genetic or common environmental factors was examined using a bivariate Cholesky decomposition model. Results The five single items that comprised the resilience assessment (social maturity, interest, psychological energy, home environment, and emotional control) all reduced risk for subsequent AUD, with social maturity showing the strongest effect. The linear effect by logistic regression showed that a one-point increase on the resilience scale was associated with a 29% decrease in odds of AUD. The Cholesky decomposition model demonstrated that the resilience-AUD relationship was largely attributable to overlapping genetic and shared environmental factors (57% and 36%, respectively). Conclusion Resilience is strongly associated with a reduction in risk for AUD. This relationship appears to be the result of overlapping genetic and shared environmental influences that impact resilience and risk of AUD, rather than a directly causal relationship. PMID:27918840

  8. 75 FR 22641 - Order Extending and Modifying Temporary Conditional Exemptions Under the Securities Exchange Act...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-29

    ... those positions. Under Eurex customer clearing, the clearing relationship and Eurex's guarantee extends... member default. The customer relationship would be governed by an agreement between the customer and the...' customers (in addition to clearing CDS transactions of members and their affiliates, as permitted by the...

  9. Vertical linear feeder to elliptical igneous saucer-shaped sills: evidences from structural observations, geochemistry and experimental modeling

    NASA Astrophysics Data System (ADS)

    Galerne, C. Y.; Galland, O.; Neumann, E. R.; Planke, S.

    2009-12-01

    The structural relationships between sills and their feeders are poorly documented because they are rarely observed in the field and difficult to image on seismic data. For instance, it is unclear whether sills are fed by pipes, dikes or other sills. Nevertheless, the geometrical relationships between sills and their feeders provide first-order constraints on magma emplacement mechanisms. Here, we investigate the structural and geochemical relationships between sills and potential feeder dikes in a remarkably well-preserved and exposed sill complex, the Golden Valley Sill Complex (GVSC), Karoo Basin, South Africa. The GVSC consists of five major saucer-shaped sills and six dikes. The Golden Valley sill itself is an elliptical saucer, with a N-S trend. A one meter thick dike (D4) crops out underneath the southern tip of the Golden Valley sill. The strike of this dike is parallel to the long axis of the Golden Valley sill. Detailed sampling and geochemical analyses of the GVSC show that each sill and dike exhibits a specific geochemical signature. The Golden Valley sill and its underlying dike D4 have identical signatures. Although there is no clear structural evidence, the consistent geometrical and geochemical relationships between the Golden Valley sill and the D4 dike suggest that this vertical linear structure is the feeder of the overlying saucer-shaped sill. In order to investigate the relationships between sills and feeders, we resorted to scaled laboratory experiments. The experiments consisted of a low-viscosity vegetable oil representing magma and a cohesive fine-grained silica flour representing brittle rocks. We placed a horizontal weak layer into the silica flour, just above the top of the inlet, to simulate strata. Such a weak layer controlled the formation of horizontal sill that subsequently turned into a transgressive sheet leading to the formation of a saucer geometry. We ran experiments with varying inlet shapes: 1) a point inlet representing a pipe-like feeder and 2) a linear feeder representing a dike-like feeder. In the experiments with point inlet, circular saucer-shaped sills formed. In the experiments with linear feeder, elliptical saucer-shaped sills formed. In the latter experiments, the long axes of the saucers were parallel to, and located directly above, the linear feeder. The experiments show that the feeder geometry has an important influence on the geometry of the emplaced sills. There are close similarities between the geometry of the Golden Valley sill and the intrusions formed in the experiments. The elliptical shape of the Golden Valley sill suggests that it was fed by an elongated feeder, probably the D4 dike. In general, our results show that the three-dimensional geometry of saucer-shaped sills observed in sedimentary basins, may constrain the shape of their feeders, i.e. their emplacement mechanisms.

  10. Imaging of arsenic traces in human hair by nano-SIMS 50

    NASA Astrophysics Data System (ADS)

    Audinot, J.-N.; Schneider, S.; Yegles, M.; Hallegot, P.; Wennig, R.; Migeon, H.-N.

    2004-06-01

    The nano-SIMS 50 allows ion imaging to be performed on microtomed hair cross-sections in order to determine the concentration and to localize the distribution of arsenic traces in hairs. Our study shows a linear relationship between the SIMS signal (As normalized with respect to CN) and the concentration determined by other analytical techniques. The advantages of SIMS imaging can be clearly proved by the capability to record quantitative distributions of As in the cross section. As a matter of fact, the nano-SIMS 50 images may allow differentiation between As located in the medulla, the cortex and the cuticle of the hair and thus distinguish between intoxication by indigestion and surface pollution of the sample.

  11. Linear relationship between water wetting behavior and microscopic interactions of super-hydrophilic surfaces.

    PubMed

    Liu, Jian; Wang, Chunlei; Guo, Pan; Shi, Guosheng; Fang, Haiping

    2013-12-21

    Using molecular dynamics simulations, we show a fine linear relationship between surface energies and microscopic Lennard-Jones parameters of super-hydrophilic surfaces. The linear slope of the super-hydrophilic surfaces is consistent with the linear slope of the super-hydrophobic, hydrophobic, and hydrophilic surfaces where stable water droplets can stand, indicating that there is a universal linear behavior of the surface energies with the water-surface van der Waals interaction that extends from the super-hydrophobic to super-hydrophilic surfaces. Moreover, we find that the linear relationship exists for various substrate types, and the linear slopes of these different types of substrates are dependent on the surface atom density, i.e., higher surface atom densities correspond to larger linear slopes. These results enrich our understanding of water behavior on solid surfaces, especially the water wetting behaviors on uncharged super-hydrophilic metal surfaces.

  12. Concentration–Response Function for Ozone and Daily Mortality: Results from Five Urban and Five Rural U.K. Populations

    PubMed Central

    Yu, Dahai; Armstrong, Ben G.; Pattenden, Sam; Wilkinson, Paul; Doherty, Ruth M.; Heal, Mathew R.; Anderson, H. Ross

    2012-01-01

    Background: Short-term exposure to ozone has been associated with increased daily mortality. The shape of the concentration–response relationship—and, in particular, if there is a threshold—is critical for estimating public health impacts. Objective: We investigated the concentration–response relationship between daily ozone and mortality in five urban and five rural areas in the United Kingdom from 1993 to 2006. Methods: We used Poisson regression, controlling for seasonality, temperature, and influenza, to investigate associations between daily maximum 8-hr ozone and daily all-cause mortality, assuming linear, linear-threshold, and spline models for all-year and season-specific periods. We examined sensitivity to adjustment for particles (urban areas only) and alternative temperature metrics. Results: In all-year analyses, we found clear evidence for a threshold in the concentration–response relationship between ozone and all-cause mortality in London at 65 µg/m3 [95% confidence interval (CI): 58, 83] but little evidence of a threshold in other urban or rural areas. Combined linear effect estimates for all-cause mortality were comparable for urban and rural areas: 0.48% (95% CI: 0.35, 0.60) and 0.58% (95% CI: 0.36, 0.81) per 10-µg/m3 increase in ozone concentrations, respectively. Seasonal analyses suggested thresholds in both urban and rural areas for effects of ozone during summer months. Conclusions: Our results suggest that health impacts should be estimated across the whole ambient range of ozone using both threshold and nonthreshold models, and models stratified by season. Evidence of a threshold effect in London but not in other study areas requires further investigation. The public health impacts of exposure to ozone in rural areas should not be overlooked. PMID:22814173

  13. Relationship between rice yield and climate variables in southwest Nigeria using multiple linear regression and support vector machine analysis

    NASA Astrophysics Data System (ADS)

    Oguntunde, Philip G.; Lischeid, Gunnar; Dietrich, Ottfried

    2018-03-01

    This study examines the variations of climate variables and rice yield and quantifies the relationships among them using multiple linear regression, principal component analysis, and support vector machine (SVM) analysis in southwest Nigeria. The climate and yield data used was for a period of 36 years between 1980 and 2015. Similar to the observed decrease ( P < 0.001) in rice yield, pan evaporation, solar radiation, and wind speed declined significantly. Eight principal components exhibited an eigenvalue > 1 and explained 83.1% of the total variance of predictor variables. The SVM regression function using the scores of the first principal component explained about 75% of the variance in rice yield data and linear regression about 64%. SVM regression between annual solar radiation values and yield explained 67% of the variance. Only the first component of the principal component analysis (PCA) exhibited a clear long-term trend and sometimes short-term variance similar to that of rice yield. Short-term fluctuations of the scores of the PC1 are closely coupled to those of rice yield during the 1986-1993 and the 2006-2013 periods thereby revealing the inter-annual sensitivity of rice production to climate variability. Solar radiation stands out as the climate variable of highest influence on rice yield, and the influence was especially strong during monsoon and post-monsoon periods, which correspond to the vegetative, booting, flowering, and grain filling stages in the study area. The outcome is expected to provide more in-depth regional-specific climate-rice linkage for screening of better cultivars that can positively respond to future climate fluctuations as well as providing information that may help optimized planting dates for improved radiation use efficiency in the study area.

  14. Spectral Dependence of the Scattering Coefficient in Case 1 and Case 2 Waters

    NASA Astrophysics Data System (ADS)

    Gould, Richard W., Jr.; Arnone, Robert A.; Martinolich, Paul M.

    1999-04-01

    An approximate linear relationship between the scattering coefficient and the wavelength of light in the visible is found in case 1 and case 2 waters. From this relationship, we estimate scattering at an unknown wavelength from scattering at a single measured wavelength. This approximation is based on measurements in a 1.5-m-thick surface layer collected with an AC9 instrument at 63 stations in the Arabian Sea, northern Gulf of Mexico, and coastal North Carolina. The light-scattering coefficient at 412 nm ranged from 0.2 to 15.1 m 1 in these waters, and the absorption coefficient at 412 nm ranged from 0.2 to 4.0 m 1 . A separate data set for 100 stations from Oceanside, California, and Chesapeake Bay, Virginia, was used to validate the relationship. Although the Oceanside waters were considerably different from the developmental data set (based on absorption-to-scattering ratios and single-scattering albedos), the average error between modeled and measured scattering values was 6.0% for the entire test data set over all wavelengths (without regard to sign). The slope of the spectral scattering relationship decreases progressively from high-scattering, turbid waters dominated by suspended sediments to lower-scattering, clear waters dominated by phytoplankton.

  15. Cognitive function and dialysis adequacy: no clear relationship.

    PubMed

    Giang, Lena M; Weiner, Daniel E; Agganis, Brian T; Scott, Tammy; Sorensen, Eric P; Tighiouart, Hocine; Sarnak, Mark J

    2011-01-01

    Cognitive impairment is common in hemodialysis patients and may be impacted by multiple patient and treatment characteristics. The impact of dialysis dose on cognitive function remains uncertain, particularly in the current era of increased dialysis dose and flux. We explored the cross-sectional relationship between dialysis adequacy and cognitive function in a cohort of maintenance hemodialysis patients. Adequacy was defined as the average of the 3 most proximate single pool Kt/V assessments. A detailed neurocognitive battery was administered during the 1st hour of dialysis. Multivariable linear regression models were adjusted for age, sex, education, race and other clinical and demographic characteristics. Among 273 patients who underwent cognitive testing, the mean (SD) age was 63 (17) years and the median dialysis duration was 13 months, 47% were woman, 22% were African American, and 48% had diabetes. The mean (SD) Kt/V was 1.51 (0.24). In univariate, parsimonious and multivariable models, there were no significant relationships between decreased cognitive function and lower Kt/V. In contrast to several older studies, there is no association between lower Kt/V and worse cognitive performance in the current era of increased dialysis dose. Future studies should address the longitudinal relationship between adequacy of dialysis and cognitive function to confirm these findings. Copyright © 2010 S. Karger AG, Basel.

  16. Estimation of Surface Air Temperature from MODIS 1km Resolution Land Surface Temperature Over Northern China

    NASA Technical Reports Server (NTRS)

    Shen, Suhung; Leptoukh, Gregory G.; Gerasimov, Irina

    2010-01-01

    Surface air temperature is a critical variable to describe the energy and water cycle of the Earth-atmosphere system and is a key input element for hydrology and land surface models. It is a very important variable in agricultural applications and climate change studies. This is a preliminary study to examine statistical relationships between ground meteorological station measured surface daily maximum/minimum air temperature and satellite remotely sensed land surface temperature from MODIS over the dry and semiarid regions of northern China. Studies were conducted for both MODIS-Terra and MODIS-Aqua by using year 2009 data. Results indicate that the relationships between surface air temperature and remotely sensed land surface temperature are statistically significant. The relationships between the maximum air temperature and daytime land surface temperature depends significantly on land surface types and vegetation index, but the minimum air temperature and nighttime land surface temperature has little dependence on the surface conditions. Based on linear regression relationship between surface air temperature and MODIS land surface temperature, surface maximum and minimum air temperatures are estimated from 1km MODIS land surface temperature under clear sky conditions. The statistical errors (sigma) of the estimated daily maximum (minimum) air temperature is about 3.8 C(3.7 C).

  17. Semiparametric methods for estimation of a nonlinear exposure-outcome relationship using instrumental variables with application to Mendelian randomization.

    PubMed

    Staley, James R; Burgess, Stephen

    2017-05-01

    Mendelian randomization, the use of genetic variants as instrumental variables (IV), can test for and estimate the causal effect of an exposure on an outcome. Most IV methods assume that the function relating the exposure to the expected value of the outcome (the exposure-outcome relationship) is linear. However, in practice, this assumption may not hold. Indeed, often the primary question of interest is to assess the shape of this relationship. We present two novel IV methods for investigating the shape of the exposure-outcome relationship: a fractional polynomial method and a piecewise linear method. We divide the population into strata using the exposure distribution, and estimate a causal effect, referred to as a localized average causal effect (LACE), in each stratum of population. The fractional polynomial method performs metaregression on these LACE estimates. The piecewise linear method estimates a continuous piecewise linear function, the gradient of which is the LACE estimate in each stratum. Both methods were demonstrated in a simulation study to estimate the true exposure-outcome relationship well, particularly when the relationship was a fractional polynomial (for the fractional polynomial method) or was piecewise linear (for the piecewise linear method). The methods were used to investigate the shape of relationship of body mass index with systolic blood pressure and diastolic blood pressure. © 2017 The Authors Genetic Epidemiology Published by Wiley Periodicals, Inc.

  18. Semiparametric methods for estimation of a nonlinear exposure‐outcome relationship using instrumental variables with application to Mendelian randomization

    PubMed Central

    Staley, James R.

    2017-01-01

    ABSTRACT Mendelian randomization, the use of genetic variants as instrumental variables (IV), can test for and estimate the causal effect of an exposure on an outcome. Most IV methods assume that the function relating the exposure to the expected value of the outcome (the exposure‐outcome relationship) is linear. However, in practice, this assumption may not hold. Indeed, often the primary question of interest is to assess the shape of this relationship. We present two novel IV methods for investigating the shape of the exposure‐outcome relationship: a fractional polynomial method and a piecewise linear method. We divide the population into strata using the exposure distribution, and estimate a causal effect, referred to as a localized average causal effect (LACE), in each stratum of population. The fractional polynomial method performs metaregression on these LACE estimates. The piecewise linear method estimates a continuous piecewise linear function, the gradient of which is the LACE estimate in each stratum. Both methods were demonstrated in a simulation study to estimate the true exposure‐outcome relationship well, particularly when the relationship was a fractional polynomial (for the fractional polynomial method) or was piecewise linear (for the piecewise linear method). The methods were used to investigate the shape of relationship of body mass index with systolic blood pressure and diastolic blood pressure. PMID:28317167

  19. Linear regression metamodeling as a tool to summarize and present simulation model results.

    PubMed

    Jalal, Hawre; Dowd, Bryan; Sainfort, François; Kuntz, Karen M

    2013-10-01

    Modelers lack a tool to systematically and clearly present complex model results, including those from sensitivity analyses. The objective was to propose linear regression metamodeling as a tool to increase transparency of decision analytic models and better communicate their results. We used a simplified cancer cure model to demonstrate our approach. The model computed the lifetime cost and benefit of 3 treatment options for cancer patients. We simulated 10,000 cohorts in a probabilistic sensitivity analysis (PSA) and regressed the model outcomes on the standardized input parameter values in a set of regression analyses. We used the regression coefficients to describe measures of sensitivity analyses, including threshold and parameter sensitivity analyses. We also compared the results of the PSA to deterministic full-factorial and one-factor-at-a-time designs. The regression intercept represented the estimated base-case outcome, and the other coefficients described the relative parameter uncertainty in the model. We defined simple relationships that compute the average and incremental net benefit of each intervention. Metamodeling produced outputs similar to traditional deterministic 1-way or 2-way sensitivity analyses but was more reliable since it used all parameter values. Linear regression metamodeling is a simple, yet powerful, tool that can assist modelers in communicating model characteristics and sensitivity analyses.

  20. A Simple Piece of Apparatus to Aid the Understanding of the Relationship between Angular Velocity and Linear Velocity

    ERIC Educational Resources Information Center

    Unsal, Yasin

    2011-01-01

    One of the subjects that is confusing and difficult for students to fully comprehend is the concept of angular velocity and linear velocity. It is the relationship between linear and angular velocity that students find difficult; most students understand linear motion in isolation. In this article, we detail the design, construction and…

  1. The Relationship between Written Coherence and Thinking.

    ERIC Educational Resources Information Center

    Goldstein, Elizabeth Odoroff

    It was hypothesized that writers of sentence pairs with clear relationships would have better recall of second sentences than would writers of sentence pairs with unclear relationships. Clear connections between sentences in sentence pairs were defined as those sentences in which the language of the first sentence was explicitly picked up in the…

  2. Cohesive zone finite element analysis of crack initiation from a butt joint’s interface corner

    DOE PAGES

    Reedy, E. D.

    2014-09-06

    The Cohesive zone (CZ) fracture analysis techniques are used to predict the initiation of crack growth from the interface corner of an adhesively bonded butt joint. In this plane strain analysis, a thin linear elastic adhesive layer is sandwiched between rigid adherends. There is no preexisting crack in the problem analyzed, and the focus is on how the shape of the traction–separation (T–U) relationship affects the predicted joint strength. Unlike the case of a preexisting interfacial crack, the calculated results clearly indicate that the predicted joint strength depends on the shape of the T–U relationship. Most of the calculations usedmore » a rectangular T–U relationship whose shape (aspect ratio) is defined by two parameters: the interfacial strength σ* and the work of separation/unit area Γ. The principal finding of this study is that for a specified adhesive layer thickness, there is any number of σ*, Γ combinations that generate the same predicted joint strength. For each combination there is a corresponding CZ length. We developed an approximate CZ-like elasticity solution to show how such combinations arise and their connection with the CZ length.« less

  3. Seasonal Blowfly Distribution and Abundance in Fragmented Landscapes. Is It Useful in Forensic Inference about Where a Corpse Has Been Decaying?

    PubMed Central

    Zabala, Jabi; Díaz, Beatriz; Saloña-Bordas, Marta I.

    2014-01-01

    Blowflies are insects of forensic interest as they may indicate characteristics of the environment where a body has been laying prior to the discovery. In order to estimate changes in community related to landscape and to assess if blowfly species can be used as indicators of the landscape where a corpse has been decaying, we studied the blowfly community and how it is affected by landscape in a 7,000 km2 region during a whole year. Using baited traps deployed monthly we collected 28,507 individuals of 10 calliphorid species, 7 of them well represented and distributed in the study area. Multiple Analysis of Variance found changes in abundance between seasons in the 7 analyzed species, and changes related to land use in 4 of them (Calliphora vomitoria, Lucilia ampullacea, L. caesar and L. illustris). Generalised Linear Model analyses of abundance of these species compared with landscape descriptors at different scales found only a clear significant relationship between summer abundance of C. vomitoria and distance to urban areas and degree of urbanisation. This relationship explained more deviance when considering the landscape composition at larger geographical scales (up to 2,500 m around sampling site). For the other species, no clear relationship between land uses and abundance was found, and therefore observed changes in their abundance patterns could be the result of other variables, probably small changes in temperature. Our results suggest that blowfly community composition cannot be used to infer in what kind of landscape a corpse has decayed, at least in highly fragmented habitats, the only exception being the summer abundance of C. vomitoria. PMID:24918607

  4. Is DNA a worm-like chain in Couette flow? In search of persistence length, a critical review.

    PubMed

    Rittman, Martyn; Gilroy, Emma; Koohya, Hashem; Rodger, Alison; Richards, Adair

    2009-01-01

    Persistence length is the foremost measure of DNA flexibility. Its origins lie in polymer theory which was adapted for DNA following the determination of BDNA structure in 1953. There is no single definition of persistence length used, and the links between published definitions are based on assumptions which may, or may not be, clearly stated. DNA flexibility is affected by local ionic strength, solvent environment, bound ligands and intrinsic sequence-dependent flexibility. This article is a review of persistence length providing a mathematical treatment of the relationships between four definitions of persistence length, including: correlation, Kuhn length, bending, and curvature. Persistence length has been measured using various microscopy, force extension and solution methods such as linear dichroism and transient electric birefringence. For each experimental method a model of DNA is required to interpret the data. The importance of understanding the underlying models, along with the assumptions required by each definition to determine a value of persistence length, is highlighted for linear dichroism data, where it transpires that no model is currently available for long DNA or medium to high shear rate experiments.

  5. Ion transport with charge-protected and non-charge-protected cations using the compensated Arrhenius formalism. Part 2. Relationship between ionic conductivity and diffusion.

    PubMed

    Petrowsky, Matt; Fleshman, Allison; Bopege, Dharshani N; Frech, Roger

    2012-08-09

    Temperature-dependent ionic conductivities and cation/anion self-diffusion coefficients are measured for four electrolyte families: TbaTf-linear primary alcohols, LiTf-linear primary alcohols, TbaTf-n-alkyl acetates, and LiTf-n-alkyl acetates. The Nernst-Einstein equation does not adequately describe the data. Instead, the compensated Arrhenius formalism is applied to both conductivity and diffusion data. General trends based on temperature and alkyl chain length are observed when conductivity is plotted against cation or anion diffusion coefficient, but there is no clear pattern to the data. However, plotting conductivity exponential prefactors against those for diffusion results in four distinct curves, one each for the alcohol and acetate families described above. Furthermore, the TbaTf-alcohol and TbaTf-acetate data are "in line" with each other. The conductivity prefactors for the LiTf-alcohol data are smaller than those for the TbaTf data. The LiTf-acetate data have the lowest conductivity prefactors. This trend in prefactors mirrors the observed trend in degree of ionic association for these electrolytes.

  6. Making sense of enthalpy of vaporization trends for ionic liquids: new experimental and simulation data show a simple linear relationship and help reconcile previous data.

    PubMed

    Verevkin, Sergey P; Zaitsau, Dzmitry H; Emel'yanenko, Vladimir N; Yermalayeu, Andrei V; Schick, Christoph; Liu, Hongjun; Maginn, Edward J; Bulut, Safak; Krossing, Ingo; Kalb, Roland

    2013-05-30

    Vaporization enthalpy of an ionic liquid (IL) is a key physical property for applications of ILs as thermofluids and also is useful in developing liquid state theories and validating intermolecular potential functions used in molecular modeling of these liquids. Compilation of the data for a homologous series of 1-alkyl-3-methylimidazolium bis(trifluoromethane-sulfonyl)imide ([C(n)mim][NTf2]) ILs has revealed an embarrassing disarray of literature results. New experimental data, based on the concurring results from quartz crystal microbalance, thermogravimetric analyses, and molecular dynamics simulation have revealed a clear linear dependence of IL vaporization enthalpies on the chain length of the alkyl group on the cation. Ambiguity of the procedure for extrapolation of vaporization enthalpies to the reference temperature 298 K was found to be a major source of the discrepancies among previous data sets. Two simple methods for temperature adjustment of vaporization enthalpies have been suggested. Resulting vaporization enthalpies obey group additivity, although the values of the additivity parameters for ILs are different from those for molecular compounds.

  7. Correlation and simple linear regression.

    PubMed

    Zou, Kelly H; Tuncali, Kemal; Silverman, Stuart G

    2003-06-01

    In this tutorial article, the concepts of correlation and regression are reviewed and demonstrated. The authors review and compare two correlation coefficients, the Pearson correlation coefficient and the Spearman rho, for measuring linear and nonlinear relationships between two continuous variables. In the case of measuring the linear relationship between a predictor and an outcome variable, simple linear regression analysis is conducted. These statistical concepts are illustrated by using a data set from published literature to assess a computed tomography-guided interventional technique. These statistical methods are important for exploring the relationships between variables and can be applied to many radiologic studies.

  8. Strengthen forensic entomology in court--the need for data exploration and the validation of a generalised additive mixed model.

    PubMed

    Baqué, Michèle; Amendt, Jens

    2013-01-01

    Developmental data of juvenile blow flies (Diptera: Calliphoridae) are typically used to calculate the age of immature stages found on or around a corpse and thus to estimate a minimum post-mortem interval (PMI(min)). However, many of those data sets don't take into account that immature blow flies grow in a non-linear fashion. Linear models do not supply a sufficient reliability on age estimates and may even lead to an erroneous determination of the PMI(min). According to the Daubert standard and the need for improvements in forensic science, new statistic tools like smoothing methods and mixed models allow the modelling of non-linear relationships and expand the field of statistical analyses. The present study introduces into the background and application of these statistical techniques by analysing a model which describes the development of the forensically important blow fly Calliphora vicina at different temperatures. The comparison of three statistical methods (linear regression, generalised additive modelling and generalised additive mixed modelling) clearly demonstrates that only the latter provided regression parameters that reflect the data adequately. We focus explicitly on both the exploration of the data--to assure their quality and to show the importance of checking it carefully prior to conducting the statistical tests--and the validation of the resulting models. Hence, we present a common method for evaluating and testing forensic entomological data sets by using for the first time generalised additive mixed models.

  9. Energetic consequences of mechanical loads.

    PubMed

    Loiselle, D S; Crampin, E J; Niederer, S A; Smith, N P; Barclay, C J

    2008-01-01

    In this brief review, we have focussed largely on the well-established, but essentially phenomenological, linear relationship between the energy expenditure of the heart (commonly assessed as the oxygen consumed per beat, oxygen consumption (VO2)) and the pressure-volume-area (PVA, the sum of pressure-volume work and a specified 'potential energy' term). We raise concerns regarding the propriety of ignoring work done during 'passive' ventricular enlargement during diastole as well as the work done against series elasticity during systole. We question the common assumption that the rate of basal metabolism is independent of ventricular volume, given the equally well-established Feng- or stretch-effect. Admittedly, each of these issues is more of conceptual than of quantitative import. We point out that the linearity of the enthalpy-PVA relation is now so well established that observed deviations from linearity are often ignored. Given that a one-dimensional equivalent of the linear VO2-PVA relation exists in papillary muscles, it seems clear that the phenomenon arises at the cellular level, rather than being a property of the intact heart. This leads us to discussion of the classes of crossbridge models that can be applied to the study of cardiac energetics. An admittedly superficial examination of the historical role played by Hooke's Law in theories of muscle contraction foreshadows deeper consideration of the thermodynamic constraints that must, in our opinion, guide the development of any mathematical model. We conclude that a satisfying understanding of the origin of the enthalpy-PVA relation awaits the development of such a model.

  10. Modelling the association of dengue fever cases with temperature and relative humidity in Jeddah, Saudi Arabia-A generalised linear model with break-point analysis.

    PubMed

    Alkhaldy, Ibrahim

    2017-04-01

    The aim of this study was to examine the role of environmental factors in the temporal distribution of dengue fever in Jeddah, Saudi Arabia. The relationship between dengue fever cases and climatic factors such as relative humidity and temperature was investigated during 2006-2009 to determine whether there is any relationship between dengue fever cases and climatic parameters in Jeddah City, Saudi Arabia. A generalised linear model (GLM) with a break-point was used to determine how different levels of temperature and relative humidity affected the distribution of the number of cases of dengue fever. Break-point analysis was performed to modelled the effect before and after a break-point (change point) in the explanatory parameters under various scenarios. Akaike information criterion (AIC) and cross validation (CV) were used to assess the performance of the models. The results showed that maximum temperature and mean relative humidity are most probably the better predictors of the number of dengue fever cases in Jeddah. In this study three scenarios were modelled: no time lag, 1-week lag and 2-weeks lag. Among these scenarios, the 1-week lag model using mean relative humidity as an explanatory variable showed better performance. This study showed a clear relationship between the meteorological variables and the number of dengue fever cases in Jeddah. The results also demonstrated that meteorological variables can be successfully used to estimate the number of dengue fever cases for a given period of time. Break-point analysis provides further insight into the association between meteorological parameters and dengue fever cases by dividing the meteorological parameters into certain break-points. Copyright © 2016 Elsevier B.V. All rights reserved.

  11. Non-invasive imaging of the levels and effects of glutathione on the redox status of mouse brain using electron paramagnetic resonance imaging

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Emoto, Miho C.; Department of Neurology, Sapporo Medical University School of Medicine, Sapporo, Hokkaido 060-8556; Matsuoka, Yuta

    Glutathione (GSH) is the most abundant non-protein thiol that buffers reactive oxygen species in the brain. GSH does not reduce nitroxides directly, but in the presence of ascorbates, addition of GSH increases ascorbate-induced reduction of nitroxides. In this study, we used electron paramagnetic resonance (EPR) imaging and the nitroxide imaging probe, 3-methoxycarbonyl-2,2,5,5-tetramethyl-piperidine-1-oxyl (MCP), to non-invasively obtain spatially resolved redox data from mouse brains depleted of GSH with diethyl maleate compared to control. Based on the pharmacokinetics of the reduction reaction of MCP in the mouse heads, the pixel-based rate constant of its reduction reaction was calculated as an index ofmore » the redox status in vivo and mapped as a “redox map”. The obtained redox maps from control and GSH-depleted mouse brains showed a clear change in the brain redox status, which was due to the decreased levels of GSH in brains as measured by a biochemical assay. We observed a linear relationship between the reduction rate constant of MCP and the level of GSH for both control and GSH-depleted mouse brains. Using this relationship, the GSH level in the brain can be estimated from the redox map obtained with EPR imaging. - Highlights: • Redox status of glutathione-depleted mouse brain was examined with EPR imaging. • Redox status of mouse brain changed depending on glutathione (GSH) levels in brains. • Linear relationship between GSH levels and redox status in brains was found. • Using this relation, estimation of GSH levels in brains is possible from EPR images.« less

  12. Impact of tobacco prices and smoke-free policy on smoking cessation, by gender and educational group: Spain, 1993-2012.

    PubMed

    Regidor, Enrique; Pascual, Cruz; Giráldez-García, Carolina; Galindo, Silvia; Martínez, David; Kunst, Anton E

    2015-12-01

    To evaluate the effect of tobacco prices and the implementation of smoke-free legislation on smoking cessation in Spain, by educational level, across the period 1993-2012. National Health Surveys data for the above two decades were used to calculate smoking cessation in people aged 25-64 years. The relationship between tobacco prices and smoking quit-ratio was estimated using multiple linear regression adjusted for time and the presence of smoke-free legislation. The immediate as well as the longer-term impact of the 2006 smoke-free law on quit-ratio was estimated using segmented linear regression analysis. The analyses were performed separately in men and women with high and low education, respectively. No relationship was observed between tobacco prices and smoking quit-ratio, except in women having a low educational level, among whom a rise in price was associated with a decrease in quit-ratio. The smoke-free law altered the smoking quit-ratio in the short term and altered also pre-existing trends. Smoking quit-ratio increased immediately after the ban - though this increase was significant only among women with a low educational level - and then decreased in subsequent years except among men with a high educational level. A clear relationship between tobacco prices and smoking quit-ratio was not observed in a recent period. After the implementation of smoke-free legislation the trend in the quit ratio in most of the socio-economic groups was different from the trend observed before implementation, so existing inequalities in smoking quit-ratio were not widened or narrowed. Copyright © 2015 Elsevier B.V. All rights reserved.

  13. Development and Evaluation of Models for the Relationship between Tree Height and Diameter at Breast Height for Chinese-Fir Plantations in Subtropical China.

    PubMed

    Li, Yan-qiong; Deng, Xiang-wen; Huang, Zhi-hong; Xiang, Wen-hua; Yan, Wen-de; Lei, Pi-feng; Zhou, Xiao-lu; Peng, Chang-hui

    2015-01-01

    Tree diameter at breast height (dbh) and height are the most important variables used in forest inventory and management as well as forest carbon-stock estimation. In order to identify the key stand variables that influence the tree height-dbh relationship and to develop and validate a suit of models for predicting tree height, data from 5961 tree samples aged from 6 years to 53 years and collected from 80 Chinese-fir plantation plots were used to fit 39 models, including 33 nonlinear models and 6 linear models, were developed and evaluated into two groups. The results showed that composite models performed better in height estimate than one-independent-variable models. Nonlinear composite Model 34 and linear composite Model 6 were recommended for predicting tree height in Chinese fir plantations with a dbh range between 4 cm and 40 cm when the dbh data for each tree and the quadratic mean dbh of the stand (Dq) and mean height of the stand (Hm) were available. Moreover, Hm could be estimated by using the formula Hm = 11.707 × l n(Dq)-18.032. Clearly, Dq was the primary stand variable that influenced the height-dbh relationship. The parameters of the models varied according to stand age and site. The inappropriate application of provincial or regional height-dbh models for predicting small tree height at local scale may result in larger uncertainties. The method and the recommended models developed in this study were statistically reliable for applications in growth and yield estimation for even-aged Chinese-fir plantation in Huitong and Changsha. The models could be extended to other regions and to other tree species only after verification in subtropical China.

  14. Development and Evaluation of Models for the Relationship between Tree Height and Diameter at Breast Height for Chinese-Fir Plantations in Subtropical China

    PubMed Central

    Li, Yan-qiong; Deng, Xiang-wen; Huang, Zhi-hong; Xiang, Wen-hua; Yan, Wen-de; Lei, Pi-feng; Zhou, Xiao-lu; Peng, Chang-hui

    2015-01-01

    Tree diameter at breast height (dbh) and height are the most important variables used in forest inventory and management as well as forest carbon-stock estimation. In order to identify the key stand variables that influence the tree height-dbh relationship and to develop and validate a suit of models for predicting tree height, data from 5961 tree samples aged from 6 years to 53 years and collected from 80 Chinese-fir plantation plots were used to fit 39 models, including 33 nonlinear models and 6 linear models, were developed and evaluated into two groups. The results showed that composite models performed better in height estimate than one-independent-variable models. Nonlinear composite Model 34 and linear composite Model 6 were recommended for predicting tree height in Chinese fir plantations with a dbh range between 4 cm and 40 cm when the dbh data for each tree and the quadratic mean dbh of the stand (Dq) and mean height of the stand (Hm) were available. Moreover, Hm could be estimated by using the formula Hm=11.707×ln(Dq)-18.032. Clearly, Dq was the primary stand variable that influenced the height-dbh relationship. The parameters of the models varied according to stand age and site. The inappropriate application of provincial or regional height-dbh models for predicting small tree height at local scale may result in larger uncertainties. The method and the recommended models developed in this study were statistically reliable for applications in growth and yield estimation for even-aged Chinese-fir plantation in Huitong and Changsha. The models could be extended to other regions and to other tree species only after verification in subtropical China. PMID:25905458

  15. Trans-cranial infrared laser stimulation induces hemodynamic and metabolic response measured by broadband near infrared spectroscopy in vivo on human forehead (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Wang, Xinlong; Nalawade, Sahil Sunil; Reddy, Divya Dhandapani; Tian, Fenghua; Gonzalez-Lima, F.; Liu, Hanli

    2017-02-01

    Transcranial infrared laser stimulation (TILS) uses infrared light (lasers or LEDs) for nondestructive and non-thermal photobiomodulation on the human brain. Although TILS has shown its beneficial effects to a variety of neurological and psychological conditions, its physiological mechanism remains unknown. Cytochrome-c-oxidase (CCO), the last enzyme in the electron transportation chain, is proposed to be the primary photoacceptor of this infrared laser. In this study, we wish to validate this proposed mechanism. We applied 8 minutes in vivo TILS on the right forehead of 11 human participants with a 1064-nm laser. Broad-band near infrared spectroscopy (bb-NIRS) from 740-900nm was also employed near the TILS site to monitor hemodynamic and metabolic responses during the stimulation and 5-minute recovery period. For rigorous comparison, we also performed similar 8-min bb-NIR measurements under placebo conditions. A multi-linear regression analysis based on the modified Beer-Lambert law was performed to estimate concentration changes of oxy-hemoglobin (Δ[HbO]), deoxy-hemoglobin (Δ[Hb]), and cytochrome-c-oxidase (Δ[CCO]). We found that TILS induced significant increases of [CCO], [HbO] and a decrease of [Hb] with dose-dependent manner as compared with placebo treatments. Furthermore, strong linear relationships or interplays between [CCO] versus [HbO] and [CCO] versus [Hb] induced by TILS were observed in vivo for the first time. These relationships have clearly revealed close coupling/relationship between the hemodynamic oxygen supply and blood volume versus up-regulation of CCO induced by photobiomodulation. Our results demonstrate the tremendous potential of bb-NIRS as a non-invasive in vivo means to study photobiomodulation mechanisms and perform treatment evaluations of TILS.

  16. Relationship Between Ktrans and K1 with Simultaneous Versus Separate MR/PET in Rabbits with VX2 Tumors.

    PubMed

    Lee, Kyung Hee; Kang, Seung Kwan; Goo, Jin Mo; Lee, Jae Sung; Cheon, Gi Jeong; Seo, Seongho; Hwang, Eui Jin

    2017-03-01

    To compare the relationship between K trans from DCE-MRI and K 1 from dynamic 13 N-NH 3 -PET, with simultaneous and separate MR/PET in the VX-2 rabbit carcinoma model. MR/PET was performed simultaneously and separately, 14 and 15 days after VX-2 tumor implantation at the paravertebral muscle. The K trans and K 1 values were estimated using an in-house software program. The relationships between K trans and K 1 were analyzed using Pearson's correlation coefficients and linear/non-linear regression function. Assuming a linear relationship, K trans and K 1 exhibited a moderate positive correlations with both simultaneous (r=0.54-0.57) and separate (r=0.53-0.69) imaging. However, while the K trans and K 1 from separate imaging were linearly correlated, those from simultaneous imaging exhibited a non-linear relationship. The amount of change in K 1 associated with a unit increase in K trans varied depending on K trans values. The relationship between K trans and K 1 may be mis-interpreted with separate MR and PET acquisition. Copyright© 2017, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

  17. What kind of Relationship is Between Body Mass Index and Body Fat Percentage?

    PubMed

    Kupusinac, Aleksandar; Stokić, Edita; Sukić, Enes; Rankov, Olivera; Katić, Andrea

    2017-01-01

    Although body mass index (BMI) and body fat percentage (B F %) are well known as indicators of nutritional status, there are insuficient data whether the relationship between them is linear or not. There are appropriate linear and quadratic formulas that are available to predict B F % from age, gender and BMI. On the other hand, our previous research has shown that artificial neural network (ANN) is a more accurate method for that. The aim of this study is to analyze relationship between BMI and B F % by using ANN and big dataset (3058 persons). Our results show that this relationship is rather quadratic than linear for both gender and all age groups. Comparing genders, quadratic relathionship is more pronounced in women, while linear relationship is more pronounced in men. Additionaly, our results show that quadratic relationship is more pronounced in old than in young and middle-age men and it is slightly more pronounced in young and middle-age than in old women.

  18. Surpassing the no-cloning limit with a heralded hybrid linear amplifier for coherent states

    PubMed Central

    Haw, Jing Yan; Zhao, Jie; Dias, Josephine; Assad, Syed M.; Bradshaw, Mark; Blandino, Rémi; Symul, Thomas; Ralph, Timothy C.; Lam, Ping Koy

    2016-01-01

    The no-cloning theorem states that an unknown quantum state cannot be cloned exactly and deterministically due to the linearity of quantum mechanics. Associated with this theorem is the quantitative no-cloning limit that sets an upper bound to the quality of the generated clones. However, this limit can be circumvented by abandoning determinism and using probabilistic methods. Here, we report an experimental demonstration of probabilistic cloning of arbitrary coherent states that clearly surpasses the no-cloning limit. Our scheme is based on a hybrid linear amplifier that combines an ideal deterministic linear amplifier with a heralded measurement-based noiseless amplifier. We demonstrate the production of up to five clones with the fidelity of each clone clearly exceeding the corresponding no-cloning limit. Moreover, since successful cloning events are heralded, our scheme has the potential to be adopted in quantum repeater, teleportation and computing applications. PMID:27782135

  19. Non-Linear Relationship between Economic Growth and CO2 Emissions in China: An Empirical Study Based on Panel Smooth Transition Regression Models

    PubMed Central

    Wang, Zheng-Xin; Hao, Peng; Yao, Pei-Yi

    2017-01-01

    The non-linear relationship between provincial economic growth and carbon emissions is investigated by using panel smooth transition regression (PSTR) models. The research indicates that, on the condition of separately taking Gross Domestic Product per capita (GDPpc), energy structure (Es), and urbanisation level (Ul) as transition variables, three models all reject the null hypothesis of a linear relationship, i.e., a non-linear relationship exists. The results show that the three models all contain only one transition function but different numbers of location parameters. The model taking GDPpc as the transition variable has two location parameters, while the other two models separately considering Es and Ul as the transition variables both contain one location parameter. The three models applied in the study all favourably describe the non-linear relationship between economic growth and CO2 emissions in China. It also can be seen that the conversion rate of the influence of Ul on per capita CO2 emissions is significantly higher than those of GDPpc and Es on per capita CO2 emissions. PMID:29236083

  20. Non-Linear Relationship between Economic Growth and CO₂ Emissions in China: An Empirical Study Based on Panel Smooth Transition Regression Models.

    PubMed

    Wang, Zheng-Xin; Hao, Peng; Yao, Pei-Yi

    2017-12-13

    The non-linear relationship between provincial economic growth and carbon emissions is investigated by using panel smooth transition regression (PSTR) models. The research indicates that, on the condition of separately taking Gross Domestic Product per capita (GDPpc), energy structure (Es), and urbanisation level (Ul) as transition variables, three models all reject the null hypothesis of a linear relationship, i.e., a non-linear relationship exists. The results show that the three models all contain only one transition function but different numbers of location parameters. The model taking GDPpc as the transition variable has two location parameters, while the other two models separately considering Es and Ul as the transition variables both contain one location parameter. The three models applied in the study all favourably describe the non-linear relationship between economic growth and CO₂ emissions in China. It also can be seen that the conversion rate of the influence of Ul on per capita CO₂ emissions is significantly higher than those of GDPpc and Es on per capita CO₂ emissions.

  1. Comparing Machine Learning Classifiers and Linear/Logistic Regression to Explore the Relationship between Hand Dimensions and Demographic Characteristics

    PubMed Central

    2016-01-01

    Understanding the relationship between physiological measurements from human subjects and their demographic data is important within both the biometric and forensic domains. In this paper we explore the relationship between measurements of the human hand and a range of demographic features. We assess the ability of linear regression and machine learning classifiers to predict demographics from hand features, thereby providing evidence on both the strength of relationship and the key features underpinning this relationship. Our results show that we are able to predict sex, height, weight and foot size accurately within various data-range bin sizes, with machine learning classification algorithms out-performing linear regression in most situations. In addition, we identify the features used to provide these relationships applicable across multiple applications. PMID:27806075

  2. Comparing Machine Learning Classifiers and Linear/Logistic Regression to Explore the Relationship between Hand Dimensions and Demographic Characteristics.

    PubMed

    Miguel-Hurtado, Oscar; Guest, Richard; Stevenage, Sarah V; Neil, Greg J; Black, Sue

    2016-01-01

    Understanding the relationship between physiological measurements from human subjects and their demographic data is important within both the biometric and forensic domains. In this paper we explore the relationship between measurements of the human hand and a range of demographic features. We assess the ability of linear regression and machine learning classifiers to predict demographics from hand features, thereby providing evidence on both the strength of relationship and the key features underpinning this relationship. Our results show that we are able to predict sex, height, weight and foot size accurately within various data-range bin sizes, with machine learning classification algorithms out-performing linear regression in most situations. In addition, we identify the features used to provide these relationships applicable across multiple applications.

  3. Electrodynamic pressure modulation of protein stability in cosolvents.

    PubMed

    Damodaran, Srinivasan

    2013-11-19

    Cosolvents affect structural stability of proteins in aqueous solutions. A clear understanding of the mechanism by which cosolvents impact protein stability is critical to understanding protein folding in a biological milieu. In this study, we investigated the Lifshitz-van der Waals dispersion interaction of seven different solutes with nine globular proteins and report that in an aqueous medium the structure-stabilizing solutes exert a positive electrodynamic pressure, whereas the structure-destabilizing solutes exert a negative electrodynamic pressure on the proteins. The net increase in the thermal denaturation temperature (ΔTd) of a protein in 1 M solution of various solutes was linearly related to the electrodynamic pressure (PvdW) between the solutes and the protein. The slope of the PvdW versus ΔTd plots was protein-dependent. However, we find a positive linear relationship (r(2) = 0.79) between the slope (i.e., d(ΔTd)/dPvdW) and the adiabatic compressibility (βs) of the proteins. Together, these results clearly indicate that the Lifshitz's dispersion forces are inextricably involved in solute-induced stabilization/destabilization of globular proteins. The positive and/or negative electrodynamic pressure generated by the solute-protein interaction across the water medium seems to be the fundamental mechanism by which solutes affect protein stability. This is at variance with the existing preferential hydration concept. The implication of these results is significant in the sense that, in addition to the hydrophobic effect that drives protein folding, the electrodynamic forces between the proteins and solutes in the biological milieu also might play a role in the folding process as well as in the stability of the folded state.

  4. Using CDOM optical properties for estimating DOC concentrations and pCO 2 in the Lower Amazon River

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Valerio, Aline de Matos; Kampel, Milton; Vantrepotte, Vincent

    Colored dissolved organic matter (CDOM) is largely responsible for the optical properties of freshwaters and coastal areas and can be used as a proxy to assess the non-optical carbon content as the dissolved organic carbon (DOC) and the partial pressure of carbon dioxide (pCO 2). Nevertheless, riverine studies that explores the former relationship are more challenging due to the spectral mixture caused by the high content of inorganic materials in the suspended sediment. Here we evaluate the spatial-temporal variability of CDOM, DOC and pCO 2, as well as the potential of CDOM absorption coefficient (aCDOM(412)) for estimating DOC concentration andmore » pCO 2 along the lower Amazon River. Our results revealed differences in the dissolved organic matter (DOM) quality between clear water (CW) tributaries and the Amazon River mainstem. A linear relationship between DOC and CDOM was observed when tributaries and mainstem are evaluated separately (Amazon waters: N=42, R2=0.74; CW: N= 13, R2 = 0.57). However, this linear relationship was not observed during periods of higher rainfall and river discharge, requiring a model specific to these time periods to be developed (N = 25, R2 = 0.58). A strong linear positive relation was found between aCDOM(412) and pCO 2( N=69, R2=0.65) along the lower river. pCO 2 was less affected by the optical difference between tributaries and mainstem water or by the presence of higher hygrometric conditions when compared to CDOM to DOC relationships. Including the river water temperature in the model improves our ability to estimate pCO 2 (N=69; R2 = 0.80). Our results also illustrate the complexity of DOM temporal dynamics in the lower Amazon River where the occurrence of extreme high and low discharge due to factors such as El Niño, can significantly alter the expected seasonal oscillation, as was the case during this study period. The ability to remotely assess both DOC and pCO 2 from CDOM optical properties highlight the importance of using remote sensing data for monitoring carbon dynamics in large running water systems worldwide.« less

  5. The dissolved organic matter as a potential soil quality indicator in arable soils of Hungary.

    PubMed

    Filep, Tibor; Draskovits, Eszter; Szabó, József; Koós, Sándor; László, Péter; Szalai, Zoltán

    2015-07-01

    Although several authors have suggested that the labile fraction of soils could be a potential soil quality indicator, the possibilities and limitations of using the dissolved organic matter (DOM) fraction for this purpose have not yet been investigated. The objective of this study was to evaluate the hypothesis that DOM is an adequate indicator of soil quality. To test this, the soil quality indices (SQI) of 190 arable soils from a Hungarian dataset were estimated, and these values were compared to DOM parameters (DOC and SUVA254). A clear difference in soil quality was found between the soil types, with low soil quality for arenosols (average SQI 0.5) and significantly higher values for gleysols, vertisols, regosols, solonetzes and chernozems. The SQI-DOC relationship could be described by non-linear regression, while a linear connection was observed between SQI and SUVA. The regression equations obtained for the dataset showed only one relatively weak significant correlation between the variables, for DOC (R (2) = 0.157(***); n = 190), while non-significant relationships were found for the DOC and SUVA254 values. However, an envelope curve operated with the datasets showed the robust potential of DOC to indicate soil quality changes, with a high R (2) value for the envelope curve regression equation. The limitations to using the DOM fraction of soils as a quality indicator are due to the contradictory processes which take place in soils in many cases.

  6. Relationship Between the Provision of Injection Services in Ambulatory Physician Offices and Prescribing Injectable Medicines.

    PubMed

    Yousefi, Naeimeh; Rashidian, Arash; Soleymani, Fatemeh; Kebriaeezade, Abbas

    2017-01-01

    Overuse of injections is a common problem in many low-income and middle income countries. While cultural factors and attitudes of both physicians and patients are important factors, physicians› financial intensives may play an important role in overprescribing of injections. This study was designed to assess the effects of providing injection- services in physicians› ambulatory offices on prescribing injectable medicines. This cross-sectional study was conducted in Tehran in 2012 -2013and included a random sample of general physicians, pediatricians and infectious disease specialists. We collected data on the provision of injection services in or in proximity of physician offices, and obtained data from physicians› prescriptions in the previous three-month period. We analyzed the data using ANOVA, Student›s t-test and linear regression methods. We obtained complete data from 465 of 600 sampled physicians. Overall 41.9% of prescriptions contained injectable medicines. 75% of physicians offered injection services in their offices. Male physicians and general physicians were more likely to offer the services, and more likely to prescribe injectables. We observed a clear linear relationship between the injection service working hours and the proportion of prescriptions containing injectables (p-value<0.001). Providing injection service in the office was directly linked with the proportion of prescriptions containing injectables. While provision of injection services may provide a direct financial benefit to physicians, it is unlikely to be able to substantially reduce injectable medicines› prescription without addressing the issue.

  7. Photochemical Reflectance Index (PRI) as a proxy of Light Use Efficiency (LUE) and transpiration in Mediterranean crop sites

    NASA Astrophysics Data System (ADS)

    LE Dantec, V.; Chebbi, W.; Boulet, G.; Merlin, O.; Lili-Chabaane, Z.; Er Raki, S.; Ceschia, E.; Khabba, S.; Fanise, P.; Zawilski, B.; Simonneaux, V.; Jarlan, L.

    2016-12-01

    The Photochemical Reflectance Index (PRI) is based on the short term reversible xanthophyll pigment changes accompanying plant stress and therefore of the associated photosynthetic activities. Strong relationships between PRI and Light Use Efficiency (LUE) were shown at leaf and canopy scales and over a wide range of species (Garbulsky et al., 2011). But very few previous works have explored the potential link with plant water status. In this study, we have first analyzed the link between PRI and LUE at canopy scale on two different crops in terms of canopy structure and crop management: olive grove (Tunisia) and wheat grown under different water regimes (irrigated or rainfed) and climate zones (France, Morocco). We have investigated the daily and seasonal dynamics of PRI; linking its variations to meteorological factors (global radiation and sun angle effects, soil water content, relative air humidity …) and plant processes. The highest correlations were mainly observed in clear skies conditions. We have found, whatever site, linear negative relationships between PRI and LUE using data acquired in midday (i.e. in solar zenithal angle condition). Linear link between PRI and sapflow measurements was also revealed. This correlation was obtained over periods characterized by a moderate soil water deficit, i.e. by when transpiration rate was mainly control by Vapor Pressure Deficit. We will then briefly presented alternative and complementary approaches to this index, to detect different level of water stress using thermal infrared emissions.

  8. Non-linearities in Holocene floodplain sediment storage

    NASA Astrophysics Data System (ADS)

    Notebaert, Bastiaan; Nils, Broothaerts; Jean-François, Berger; Gert, Verstraeten

    2013-04-01

    Floodplain sediment storage is an important part of the sediment cascade model, buffering sediment delivery between hillslopes and oceans, which is hitherto not fully quantified in contrast to other global sediment budget components. Quantification and dating of floodplain sediment storage is data and financially demanding, limiting contemporary estimates for larger spatial units to simple linear extrapolations from a number of smaller catchments. In this paper we will present non-linearities in both space and time for floodplain sediment budgets in three different catchments. Holocene floodplain sediments of the Dijle catchment in the Belgian loess region, show a clear distinction between morphological stages: early Holocene peat accumulation, followed by mineral floodplain aggradation from the start of the agricultural period on. Contrary to previous assumptions, detailed dating of this morphological change at different shows an important non-linearity in geomorphologic changes of the floodplain, both between and within cross sections. A second example comes from the Pre-Alpine French Valdaine region, where non-linearities and complex system behavior exists between (temporal) patterns of soil erosion and floodplain sediment deposition. In this region Holocene floodplain deposition is characterized by different cut-and-fill phases. The quantification of these different phases shows a complicated image of increasing and decreasing floodplain sediment storage, which hampers the image of increasing sediment accumulation over time. Although fill stages may correspond with large quantities of deposited sediment and traditionally calculated sedimentation rates for such stages are high, they do not necessary correspond with a long-term net increase in floodplain deposition. A third example is based on the floodplain sediment storage in the Amblève catchment, located in the Belgian Ardennes uplands. Detailed floodplain sediment quantification for this catchments shows that a strong multifractality is present in the scaling relationship between sediment storage and catchment area, depending on geomorphic landscape properties. Extrapolation of data from one spatial scale to another inevitably leads to large errors: when only the data of the upper floodplains are considered, a regression analysis results in an overestimation of total floodplain deposition for the entire catchment of circa 115%. This example demonstrates multifractality and related non-linearity in scaling relationships, which influences extrapolations beyond the initial range of measurements. These different examples indicate how traditional extrapolation techniques and assumptions in sediment budget studies can be challenged by field data, further complicating our understanding of these systems. Although simplifications are often necessary when working on large spatial scale, such non-linearities may form challenges for a better understanding of system behavior.

  9. Non-Linear Concentration-Response Relationships between Ambient Ozone and Daily Mortality.

    PubMed

    Bae, Sanghyuk; Lim, Youn-Hee; Kashima, Saori; Yorifuji, Takashi; Honda, Yasushi; Kim, Ho; Hong, Yun-Chul

    2015-01-01

    Ambient ozone (O3) concentration has been reported to be significantly associated with mortality. However, linearity of the relationships and the presence of a threshold has been controversial. The aim of the present study was to examine the concentration-response relationship and threshold of the association between ambient O3 concentration and non-accidental mortality in 13 Japanese and Korean cities from 2000 to 2009. We selected Japanese and Korean cities which have population of over 1 million. We constructed Poisson regression models adjusting daily mean temperature, daily mean PM10, humidity, time trend, season, year, day of the week, holidays and yearly population. The association between O3 concentration and mortality was examined using linear, spline and linear-threshold models. The thresholds were estimated for each city, by constructing linear-threshold models. We also examined the city-combined association using a generalized additive mixed model. The mean O3 concentration did not differ greatly between Korea and Japan, which were 26.2 ppb and 24.2 ppb, respectively. Seven out of 13 cities showed better fits for the spline model compared with the linear model, supporting a non-linear relationships between O3 concentration and mortality. All of the 7 cities showed J or U shaped associations suggesting the existence of thresholds. The range of city-specific thresholds was from 11 to 34 ppb. The city-combined analysis also showed a non-linear association with a threshold around 30-40 ppb. We have observed non-linear concentration-response relationship with thresholds between daily mean ambient O3 concentration and daily number of non-accidental death in Japanese and Korean cities.

  10. Functions Represented as Linear Sequential Data: Relationships between Presentation and Student Responses

    ERIC Educational Resources Information Center

    Ayalon, Michal; Watson, Anne; Lerman, Steve

    2015-01-01

    This study investigates students' ways of attending to linear sequential data in two tasks, and conjectures possible relationships between those ways and elements of the task design. Drawing on the substantial literature about such situations, we focus for this paper on linear rate of change, and on covariation and correspondence approaches to…

  11. Linear Equating for the NEAT Design: Parameter Substitution Models and Chained Linear Relationship Models

    ERIC Educational Resources Information Center

    Kane, Michael T.; Mroch, Andrew A.; Suh, Youngsuk; Ripkey, Douglas R.

    2009-01-01

    This paper analyzes five linear equating models for the "nonequivalent groups with anchor test" (NEAT) design with internal anchors (i.e., the anchor test is part of the full test). The analysis employs a two-dimensional framework. The first dimension contrasts two general approaches to developing the equating relationship. Under a "parameter…

  12. A Comparison of Linear and Systems Thinking Approaches for Program Evaluation Illustrated Using the Indiana Interdisciplinary GK-12

    ERIC Educational Resources Information Center

    Dyehouse, Melissa; Bennett, Deborah; Harbor, Jon; Childress, Amy; Dark, Melissa

    2009-01-01

    Logic models are based on linear relationships between program resources, activities, and outcomes, and have been used widely to support both program development and evaluation. While useful in describing some programs, the linear nature of the logic model makes it difficult to capture the complex relationships within larger, multifaceted…

  13. Analysis of actinic flux profiles measured from an ozonesonde balloon

    NASA Astrophysics Data System (ADS)

    Wang, P.; Allaart, M.; Knap, W. H.; Stammes, P.

    2015-04-01

    A green light sensor has been developed at KNMI to measure actinic flux profiles using an ozonesonde balloon. In total, 63 launches with ascending and descending profiles were performed between 2006 and 2010. The measured uncalibrated actinic flux profiles are analysed using the Doubling-Adding KNMI (DAK) radiative transfer model. Values of the cloud optical thickness (COT) along the flight track were taken from the Spinning Enhanced Visible and Infrared Imager (SEVIRI) Cloud Physical Properties (CPP) product. The impact of clouds on the actinic flux profile is evaluated on the basis of the cloud modification factor (CMF) at the cloud top and cloud base, which is the ratio between the actinic fluxes for cloudy and clear-sky scenes. The impact of clouds on the actinic flux is clearly detected: the largest enhancement occurs at the cloud top due to multiple scattering. The actinic flux decreases almost linearly from cloud top to cloud base. Above the cloud top the actinic flux also increases compared to clear-sky scenes. We find that clouds can increase the actinic flux to 2.3 times the clear-sky value at cloud top and decrease it to about 0.05 at cloud base. The relationship between CMF and COT agrees well with DAK simulations, except for a few outliers. Good agreement is found between the DAK-simulated actinic flux profiles and the observations for single-layer clouds in fully overcast scenes. The instrument is suitable for operational balloon measurements because of its simplicity and low cost. It is worth further developing the instrument and launching it together with atmospheric chemistry composition sensors.

  14. Using Theoretical Descriptors in Structural Activity Relationships: 4. Molecular Orbital Basicity and Electrostatic Basicity

    DTIC Science & Technology

    1988-11-01

    rates.6 The Hammet equation , also called the Linear Free Energy Relationship (LFER) because of the relationship of the Gibb’s Free Energy to the... equations for numerous biological and physicochemical properties. Linear Solvation Enery Relationship (LSER), a sub-set of QSAR have been used by...originates from thermodynamics, where Hammet recognized the relationship of structure to the Gibb’s Free Energy, and ultimately to equilibria and reaction

  15. Narcissism and Newlywed Marriage: Partner Characteristics and Marital Trajectories

    PubMed Central

    Lavner, Justin A.; Lamkin, Joanna; Miller, Joshua D.; Campbell, W. Keith; Karney, Benjamin R.

    2015-01-01

    Despite narcissism’s relation with interpersonal dysfunction, surprisingly little empirical research has been devoted to understanding narcissism’s effect on intimate relationships in general or marital relationships in particular. The current study addressed this gap using longitudinal data from a community sample of 146 newlywed couples assessed 6 times over the first four years of marriage. First, we examined partner characteristics associated with higher levels of narcissism to determine the degree to which couples were matched on narcissism and related traits. Second, we examined how narcissism predicted the trajectory of marital quality over time, testing narcissism’s association with initial levels of relationship functioning (the intercept) and changes in relationship functioning (the slope). Results indicated a small degree of homophily but otherwise no clear pattern of partner characteristics for individuals higher in narcissism. Hierarchical linear modeling indicated that wives’ total narcissism and entitlement/ exploitativeness scores predicted the slope of marital quality over time, including steeper declines in marital satisfaction and steeper increases in marital problems. Husbands’ narcissism scores generally had few effects on their own marital quality or that of their wives. These findings are notable in indicating that the effects of personality characteristics on marital functioning may take some time to manifest themselves, even if they were present from early in the marriage. Future research into the mediating psychological and interpersonal processes that link wives’ narcissism with poorer marital functioning over time would be valuable. PMID:26098378

  16. [Socioeconomical level and behavior in school-age children: the mediating role of parents].

    PubMed

    Ulloa Vidal, Natalia; Cova Solar, Félix; Bustos N, Claudio

    2017-06-01

    A determinant of particular relevance in human development is the socioeconomic status (SES) and, specifically, low SES and poverty. Likewise, family environment is essential in the development of children and a potential mediator or moderator of the effect of broader social conditions. To analyze the role of parenting stress as a mediating variable of the relationship between SES and both externalized and internalized behaviors in preschool children. Descriptive secondary base study based on the Longitudinal Survey of Chilean First Infancy that selected a stratified sample, representative by clusters, of 9.996 children from 3 to 5 years old and their caregivers, that completed a battery of instruments for measuring SES variables, parenting stress and externalized and internalized behaviors. The analysis used a linear model with least square estimate. As hypothesis testing, the Dm (an adaptation of the F-test for multiple imputation method) was used. The mediation model of parenting stress in the relationship between SES and both externalized and internalized behaviors was confirmed for the latter; regarding externalized behaviors a model of moderation was observed, being the stress influence lower on the low SES. Parental stress showed a clear relationship with the presence of externalized and internalized behaviors, stronger than the SES. The relationship between SES and parenting stress is very important to understand the processes that affect children’s development.

  17. Sizing the association between lifestyle behaviours and fatness in a large, heterogeneous sample of youth of multiple ethnicities from 4 countries.

    PubMed

    Sluyter, John D; Scragg, Robert K R; Plank, Lindsay D; Waqa, Gade D; Fotu, Kalesita F; Swinburn, Boyd A

    2013-10-12

    The magnitude of the relationship between lifestyle risk factors for obesity and adiposity is not clear. The aim of this study was to clarify this in order to determine the level of importance of lifestyle factors in obesity aetiology. A cross-sectional analysis was carried out on data on youth who were not trying to change weight (n = 5714), aged 12 to 22 years and from 8 ethnic groups living in New Zealand, Australia, Fiji and Tonga. Demographic and lifestyle data were measured by questionnaires. Fatness was measured by body mass index (BMI), BMI z-score and bioimpedance analysis, which was used to estimate percent body fat and total fat mass (TFM). Associations between lifestyle and body composition variables were examined using linear regression and forest plots. TV watching was positively related to fatness in a dose-dependent manner. Strong, dose-dependent associations were observed between fatness and soft drink consumption (positive relationship), breakfast consumption (inverse relationship) and after-school physical activity (inverse relationship). Breakfast consumption-fatness associations varied in size across ethnic groups. Lifestyle risk factors for obesity were associated with percentage differences in body composition variables that were greatest for TFM and smallest for BMI. Lifestyle factors were most strongly related to TFM, which suggests that studies that use BMI alone to quantify fatness underestimate the full effect of lifestyle on adiposity. This study clarifies the size of lifestyle-fatness relationships observed in previous studies.

  18. Investigating Years 7 to 12 students' knowledge of linear relationships through different contexts and representations

    NASA Astrophysics Data System (ADS)

    Wilkie, Karina J.; Ayalon, Michal

    2018-02-01

    A foundational component of developing algebraic thinking for meaningful calculus learning is the idea of "function" that focuses on the relationship between varying quantities. Students have demonstrated widespread difficulties in learning calculus, particularly interpreting and modeling dynamic events, when they have a poor understanding of relationships between variables. Yet, there are differing views on how to develop students' functional thinking over time. In the Australian curriculum context, linear relationships are introduced to lower secondary students with content that reflects a hybrid of traditional and reform algebra pedagogy. This article discusses an investigation into Australian secondary students' understanding of linear functional relationships from Years 7 to 12 (approximately 12 to 18 years old; n = 215) in their approaches to three tasks (finding rate of change, pattern generalisation and interpretation of gradient) involving four different representations (table, geometric growing pattern, equation and graph). From the findings, it appears that these students' knowledge of linear functions remains context-specific rather than becoming connected over time.

  19. 78 FR 35335 - Self-Regulatory Organizations; ICE Clear Europe Limited; Notice of Filing of Amendment No. 2 to...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-12

    ...-Regulatory Organizations; ICE Clear Europe Limited; Notice of Filing of Amendment No. 2 to Proposed Rule...\\ notice is hereby given that on June 4, 2013, ICE Clear Europe Limited (``ICE Clear Europe'') filed with... proposed rule changes to implement a clearing relationship in which ICE Clear Europe will clear contracts...

  20. Stress and prevalence of hearing problems in the Swedish working population

    PubMed Central

    2011-01-01

    Background Current human and experimental studies are indicating an association between stress and hearing problems; however potential risk factors have not been established. Hearing problems are projected to become among the top ten disabilities according to the WHO in the near future. Therefore a better understanding of the relationships between stress and hearing is warranted. Here we describe the prevalence of two common hearing problems, i.e. hearing complaints and tinnitus, in relation to different work-and health-related stressors. Methods A total of 18,734 individuals were invited to participate in the study, out of which 9,756 (52%) enrolled. Results The results demonstrate a clear and mostly linear relationship between higher prevalence of hearing problems (tinnitus or hearing loss or both) and different stressors, e.g. occupational, poorer self-rated health, long-term illness, poorer sleep quality, and higher burnout scores. Conclusions The present study unambiguously demonstrates associations between hearing problems and various stressors that have not been previously described for the auditory system. These findings will open new avenues for future investigations. PMID:21345187

  1. Uranium Stable Isotopes: A Proxy For Productivity Or Ocean Oxygenation?

    NASA Astrophysics Data System (ADS)

    Severmann, S.

    2015-12-01

    Uranium elemental abundances in sediments have traditionally been used to reconstruct primary productivity and carbon flux in the ocean. 238U/235U isotope compositions, in contrast, are currently understood to reflect the extent of bottom water anoxia in the ocean. A review of our current understanding of authigenic U enrichment mechanism into reducing sediments suggests that a revision of this interpretation is warranted. Specifically, the current interpretation of U isotope effects in suboxic vs. anoxic deposits has not taken into account the well-documented linear relationship with organic C burial rates. Although organic C rain rates (i.e., surface productivity) and bottom water oxygenation are clearly related, distinction between these two environmental controls is conceptually important as it relates to the mechanism of enhanced C burial and ultimately the strength of the biological pump. Here we will review new and existing data to test the hypothesis that the isotope composition of authigenic U in reducing sediments are best described by their relationship with parameters related to organic carbon delivery and burial, rather than bottom water oxygen concentration.

  2. The relationship between treatment access and spending in a managed behavioral health organization.

    PubMed

    Cuffel, B J; Regier, D

    2001-07-01

    This study replicated an earlier study that showed a linear relationship between level of treatment access and behavioral health spending. The study reported here examined whether this relationship varies by important characteristics of behavioral health plans. Access rates and total spending over a five- to seven-year period were computed for 30 behavioral health plans. Regression analysis was used to estimate the relationship between access and spending and to examine whether it varied with the characteristics of benefit plans. A linear relationship was found between level of treatment access and behavioral health spending. However, the relationship closely paralleled that found in the earlier study only for benefit plans with an employee assistance program linked to the managed behavioral health organization and for plans that do not allow the use of out-of-network providers. The results of this study replicate those of the earlier study in showing a linear relationship between access and spending, but they suggest that the magnitude of this relationship may vary according to key plan characteristics.

  3. Linear Relationship between Resilience, Learning Approaches, and Coping Strategies to Predict Achievement in Undergraduate Students

    PubMed Central

    de la Fuente, Jesús; Fernández-Cabezas, María; Cambil, Matilde; Vera, Manuel M.; González-Torres, Maria Carmen; Artuch-Garde, Raquel

    2017-01-01

    The aim of the present research was to analyze the linear relationship between resilience (meta-motivational variable), learning approaches (meta-cognitive variables), strategies for coping with academic stress (meta-emotional variable) and academic achievement, necessary in the context of university academic stress. A total of 656 students from a southern university in Spain completed different questionnaires: a resiliency scale, a coping strategies scale, and a study process questionnaire. Correlations and structural modeling were used for data analyses. There was a positive and significant linear association showing a relationship of association and prediction of resilience to the deep learning approach, and problem-centered coping strategies. In a complementary way, these variables positively and significantly predicted the academic achievement of university students. These results enabled a linear relationship of association and consistent and differential prediction to be established among the variables studied. Implications for future research are set out. PMID:28713298

  4. Embracing complexity: theory, cases and the future of bioethics.

    PubMed

    Wilson, James

    2014-01-01

    This paper reflects on the relationship between theory and practice in bioethics, by using various concepts drawn from debates on innovation in healthcare research--in particular debates around how best to connect up blue skies 'basic' research with practical innovations that can improve human lives. It argues that it is a mistake to assume that the most difficult and important questions in bioethics are the most abstract ones, and also a mistake to assume that getting clear about abstract cases will automatically be of much help in getting clear about more complex cases. It replaces this implicitly linear model with a more complex one that draws on the idea of translational research in healthcare. On the translational model, there is a continuum of cases from the most simple and abstract (thought experiments) to the most concrete and complex (real world cases). Insights need to travel in both directions along this continuum--from the more abstract to the more concrete and from the more concrete to the more abstract. The paper maps out some difficulties in moving from simpler to more complex cases, and in doing so makes recommendations about the future of bioethics.

  5. Basin-scale observations of isoprene and monoterpenes in the Arctic and Atlantic Oceans

    NASA Astrophysics Data System (ADS)

    Carpenter, L.; Hackenberg, S.; Andrews, S.; Minaeian, J.; Chance, R.; Arnold, S.; Spracklen, D. V.; Walker, H.; Brewin, R. J.; Tarran, G.; Tilstone, G.; Small, A.; Bouman, H. A.

    2016-12-01

    We report surface ocean concentrations, atmospheric mixing ratios and calculated sea-to-air fluxes of isoprene and six monoterpenes (α- and β-pinene, myrcene, Δ 3-carene, ocimene, and limonene) spanning approximately 130 degrees of latitude (80 °N- 50 °S) in the Arctic and Atlantic Oceans. Oceanic isoprene concentrations showed covariance with a number of concurrently monitored biological parameters, and these relationships were dependent on sea surface temperatures. Parameterisations of isoprene seawater concentrations based on linear regression analyses of these relationships perform well for Arctic and Atlantic data. Levels of all monoterpenes were generally low, with oceanic concentrations ranging from below the detection limit of <1 pmol L-1 to 5 pmol L-1 . In air, monoterpene mixing ratios varied from below the detection limit ( 1 pptv) to 5 pptv, after careful filtering for ship-related contamination. Unlike in previous studies, no clear trends or relationships of the monoterpenes with biological data were found. Limonene showed generally the highest levels in water (up to 84 pmol L-1 in the Atlantic Ocean) and air; however this was attributed mostly to shipborne contamination. We calculate global sea-air fluxes of isoprene and monoterpenes based on this data and compare to previous estimates.

  6. Predicting the early therapeutic alliance in the treatment of drug misuse.

    PubMed

    Meier, Petra S; Donmall, Michael C; Barrowclough, Christine; McElduff, Patrick; Heller, Richard F

    2005-04-01

    To predict the early therapeutic alliance from a range of potentially relevant factors, including clients' social relationships, motivation and psychological resources, and counsellors' professional experience and ex-user status. The study recruited 187 clients starting residential rehabilitation treatment for drug misuse in three UK services. Counsellor and client information was assessed at intake, and client and counsellor ratings of the alliance were obtained during weeks 1, 2 and 3. The intake assessment battery included scales on psychological wellbeing, treatment motivation, coping strategies and attachment style. Client and counsellor versions of the Working Alliance Inventory (WAI-S) were used for weekly alliance measurement. Hierarchical linear models were used to examine the relationship between alliance and predictor variables. Clients who had better motivation, coping strategies, social support and a secure attachment style were more likely to develop good alliances. Findings with regard to counsellor characteristics were not clear cut: clients rated their relationships with ex-user counsellors, experienced counsellors and male counsellors as better, but more experienced counsellors rated their alliances as worse. The findings offer important leads as to what interventions might improve the therapeutic alliance. Further work will need to establish whether the therapeutic alliance and ultimately treatment outcomes can be enhanced by working on improving clients' motivation and psychosocial resources.

  7. Relationship between the ability of sunscreens containing 2-ethylhexyl-4'-methoxycinnamate to protect against UVR-induced inflammation, depletion of epidermal Langerhans (Ia+) cells and suppression of alloactivating capacity of murine skin in vivo.

    PubMed

    Walker, S L; Morris, J; Chu, A C; Young, A R

    1994-01-01

    The UVB sunscreen 2-ethylhexyl-4'-methoxycinnamate was evaluated in hairless albino mouse skin for its ability to inhibit UVR-induced (i) oedema, (ii) epidermal Langerhans cell (Ia+) depletion and (iii) suppression of the alloactivating capacity of epidermal cells (mixed epidermal cell-lymphocyte reaction, MECLR). The sunscreen, prepared at 9% in ethanol or a cosmetic lotion, was applied prior to UVB/UVA irradiation. In some experiments there was a second application halfway through the irradiation. Single applications in both vehicles gave varying degrees of protection from oedema and Langerhans cell depletion but afforded no protection from suppression of MECLR. When the sunscreens were applied twice there was improved protection from oedema and Langerhans cell depletion and complete protection was afforded from suppression of MECLR. There was a clear linear relationship between Langerhans cell numbers and oedema with and without sunscreen application. The relationship between Langerhans cell numbers and MECLR was more complex. These data confirm published discrepancies between protection from oedema (a model for human erythema) and endpoints with immunological significance, but show that 2-ethylhexyl-4'-methoxycinnamate can afford complete immunoprotection, although protection is dependent on the application rate and vehicle.

  8. Evaluating the relationship between leaf chlorophyll concentration and SPAD-502 chlorophyll meter readings.

    PubMed

    Uddling, J; Gelang-Alfredsson, J; Piikki, K; Pleijel, H

    2007-01-01

    Relationships between chlorophyll concentration ([chl]) and SPAD values were determined for birch, wheat, and potato. For all three species, the relationships were non-linear with an increasing slope with increasing SPAD. The relationships for birch and wheat were strong (r (2) approximately 0.9), while the potato relationship was comparatively weak (r (2) approximately 0.5). Birch and wheat had very similar relationships when the chlorophyll concentration was expressed per unit leaf area, but diverged when it was expressed per unit fresh weight. Furthermore, wheat showed similar SPAD-[chl] relationships for two different cultivars and during two different growing seasons. The curvilinear shape of the SPAD-[chl] relationships agreed well with the simulated effects of non-uniform chlorophyll distribution across the leaf surface and multiple scattering, causing deviations from linearity in the high and low SPAD range, respectively. The effect of non-uniformly distributed chlorophyll is likely to be more important in explaining the non-linearity in the empirical relationships, since the effect of scattering was predicted to be comparatively weak. The simulations were based on the algorithm for the calculation of SPAD-502 output values. We suggest that SPAD calibration curves should generally be parameterised as non-linear equations, and we hope that the relationships between [chl] and SPAD and the simulations of the present study can facilitate the interpretation of chlorophyll meter calibrations in relation to optical properties of leaves in future studies.

  9. 78 FR 13130 - Self-Regulatory Organizations; ICE Clear Europe Limited; Order Approving Proposed Rule Change, as...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-26

    ... already the case for single-name CDS). Recognizing the highly correlated relationship between long-short...' proprietary positions. ICE Clear Europe does not currently clear CDS positions of customers of its Clearing Members, but it plans to introduce customer clearing for CDS upon receipt of applicable regulatory...

  10. Axial calibration methods of piezoelectric load sharing dynamometer

    NASA Astrophysics Data System (ADS)

    Zhang, Jun; Chang, Qingbing; Ren, Zongjin; Shao, Jun; Wang, Xinlei; Tian, Yu

    2018-06-01

    The relationship between input and output of load sharing dynamometer is seriously non-linear in different loading points of a plane, so it's significant for accutately measuring force to precisely calibrate the non-linear relationship. In this paper, firstly, based on piezoelectric load sharing dynamometer, calibration experiments of different loading points are performed in a plane. And then load sharing testing system is respectively calibrated based on BP algorithm and ELM (Extreme Learning Machine) algorithm. Finally, the results show that the calibration result of ELM is better than BP for calibrating the non-linear relationship between input and output of loading sharing dynamometer in the different loading points of a plane, which verifies that ELM algorithm is feasible in solving force non-linear measurement problem.

  11. Identification of Large Space Structures on Orbit

    DTIC Science & Technology

    1986-09-01

    requires only the eigenvector corresponding to the eigenvector 93 .:. ,S --- k’.’ L derivative being calculated. However, a set of linear algebraic ...Journal of Guidance, Control and Dynamics. 204. Noble, B. and J. W. Daniel, Applied Linear Algebra , Prentice-Hall, Inc., 1977. 205. Nurre, G. S., R. S...4.2.1. Linear Relationships . . . . . . . . . . 114 4.2.2. Nonlinear Relationships . . . . . . . . . 120 4.3. Series Expansion Methods

  12. Twist Model Development and Results from the Active Aeroelastic Wing F/A-18 Aircraft

    NASA Technical Reports Server (NTRS)

    Lizotte, Andrew M.; Allen, Michael J.

    2007-01-01

    Understanding the wing twist of the active aeroelastic wing (AAW) F/A-18 aircraft is a fundamental research objective for the program and offers numerous benefits. In order to clearly understand the wing flexibility characteristics, a model was created to predict real-time wing twist. A reliable twist model allows the prediction of twist for flight simulation, provides insight into aircraft performance uncertainties, and assists with computational fluid dynamic and aeroelastic issues. The left wing of the aircraft was heavily instrumented during the first phase of the active aeroelastic wing program allowing deflection data collection. Traditional data processing steps were taken to reduce flight data, and twist predictions were made using linear regression techniques. The model predictions determined a consistent linear relationship between the measured twist and aircraft parameters, such as surface positions and aircraft state variables. Error in the original model was reduced in some cases by using a dynamic pressure-based assumption. This technique produced excellent predictions for flight between the standard test points and accounted for nonlinearities in the data. This report discusses data processing techniques and twist prediction validation, and provides illustrative and quantitative results.

  13. Twist Model Development and Results From the Active Aeroelastic Wing F/A-18 Aircraft

    NASA Technical Reports Server (NTRS)

    Lizotte, Andrew; Allen, Michael J.

    2005-01-01

    Understanding the wing twist of the active aeroelastic wing F/A-18 aircraft is a fundamental research objective for the program and offers numerous benefits. In order to clearly understand the wing flexibility characteristics, a model was created to predict real-time wing twist. A reliable twist model allows the prediction of twist for flight simulation, provides insight into aircraft performance uncertainties, and assists with computational fluid dynamic and aeroelastic issues. The left wing of the aircraft was heavily instrumented during the first phase of the active aeroelastic wing program allowing deflection data collection. Traditional data processing steps were taken to reduce flight data, and twist predictions were made using linear regression techniques. The model predictions determined a consistent linear relationship between the measured twist and aircraft parameters, such as surface positions and aircraft state variables. Error in the original model was reduced in some cases by using a dynamic pressure-based assumption and by using neural networks. These techniques produced excellent predictions for flight between the standard test points and accounted for nonlinearities in the data. This report discusses data processing techniques and twist prediction validation, and provides illustrative and quantitative results.

  14. Anisotropy of susceptibility in rocks which are magnetically nonlinear even in low fields

    NASA Astrophysics Data System (ADS)

    Hrouda, František; Chadima, Martin; Ježek, Josef

    2018-06-01

    Theory of the low-field anisotropy of magnetic susceptibility (AMS) assumes a linear relationship between magnetization and magnetizing field, resulting in field-independent susceptibility. This is valid for diamagnetic and paramagnetic minerals by definition and also for pure magnetite, while in titanomagnetite, pyrrhotite and hematite the susceptibility may be clearly field-dependent even in low fields used in common AMS meter. Consequently, the use of the linear AMS theory is fully legitimate in the former minerals, but in principle incorrect in the latter ones. Automated measurement of susceptibility in 320 directions in variable low-fields ranging from 5 to 700 A m-1 was applied to more than 100 specimens of various pyrrhotite-bearing and titanomagnetite-bearing rocks. Data analysis showed that the anisotropic susceptibility remains well represented by an ellipsoid in the entire low-field span even though the ellipsoid increases its volume and eccentricity. The principal directions do not change their orientations with low-field in most specimens. Expressions for susceptibility as a function of field were found in the form of diagonal tensor whose elements are polynomials of low order. In a large proportion of samples, the susceptibility expressions can be further simplified to have one common skeleton polynomial.

  15. The brain adjusts grip forces differently according to gravity and inertia: a parabolic flight experiment

    PubMed Central

    White, Olivier

    2015-01-01

    In everyday life, one of the most frequent activities involves accelerating and decelerating an object held in precision grip. In many contexts, humans scale and synchronize their grip force (GF), normal to the finger/object contact, in anticipation of the expected tangential load force (LF), resulting from the combination of the gravitational and the inertial forces. In many contexts, GF and LF are linearly coupled. A few studies have examined how we adjust the parameters–gain and offset–of this linear relationship. However, the question remains open as to how the brain adjusts GF regardless of whether LF is generated by different combinations of weight and inertia. Here, we designed conditions to generate equivalent magnitudes of LF by independently varying mass and movement frequency. In a control experiment, we directly manipulated gravity in parabolic flights, while other factors remained constant. We show with a simple computational approach that, to adjust GF, the brain is sensitive to how LFs are produced at the fingertips. This provides clear evidence that the analysis of the origin of LF is performed centrally, and not only at the periphery. PMID:25717293

  16. Nonlinear acoustics experimental characterization of microstructure evolution in Inconel 617

    NASA Astrophysics Data System (ADS)

    Yao, Xiaochu; Liu, Yang; Lissenden, Cliff J.

    2014-02-01

    Inconel 617 is a candidate material for the intermediate heat exchanger in a very high temperature reactor for the next generation nuclear power plant. This application will require the material to withstand fatigue-ratcheting interaction at temperatures up to 950°C. Therefore nondestructive evaluation and structural health monitoring are important capabilities. Acoustic nonlinearity (which is quantified in terms of a material parameter, the acoustic nonlinearity parameter, β) has been proven to be sensitive to microstructural changes in material. This research develops a robust experimental procedure to track the evolution of damage precursors in laboratory tested Inconel 617 specimens using ultrasonic bulk waves. The results from the acoustic non-linear tests are compared with stereoscope surface damage results. Therefore, the relationship between acoustic nonlinearity and microstructural evaluation can be clearly demonstrated for the specimens tested.

  17. Toward a dynamical theory of body movement in musical performance

    PubMed Central

    Demos, Alexander P.; Chaffin, Roger; Kant, Vivek

    2014-01-01

    Musicians sway expressively as they play in ways that seem clearly related to the music, but quantifying the relationship has been difficult. We suggest that a complex systems framework and its accompanying tools for analyzing non-linear dynamical systems can help identify the motor synergies involved. Synergies are temporary assemblies of parts that come together to accomplish specific goals. We assume that the goal of the performer is to convey musical structure and expression to the audience and to other performers. We provide examples of how dynamical systems tools, such as recurrence quantification analysis (RQA), can be used to examine performers' movements and relate them to the musical structure and to the musician's expressive intentions. We show how detrended fluctuation analysis (DFA) can be used to identify synergies and discover how they are affected by the performer's expressive intentions. PMID:24904490

  18. Electric-field-control of magnetic anisotropy of Co0.6Fe0.2B0.2/oxide stacks using reduced voltage

    NASA Astrophysics Data System (ADS)

    Kita, Koji; Abraham, David W.; Gajek, Martin J.; Worledge, D. C.

    2012-08-01

    We have demonstrated purely electrical manipulation of the magnetic anisotropy of a Co0.6Fe0.2B0.2 film by applying only 8 V across the CoFeB/oxide stack. A clear transition from in-plane to perpendicular anisotropy was observed. The quantitative relationship between interface anisotropy energy and the applied electric-field was determined from the linear voltage dependence of the saturation field. By comparing the dielectric stacks of MgO/Al2O3 and MgO/HfO2/Al2O3, enhanced voltage control was also demonstrated, due to the higher dielectric constant of the HfO2. These results suggest the feasibility of purely electrical control of magnetization with small voltage bias for spintronics applications.

  19. Dose-response relationships in a microneutralization test for foot-and-mouth disease viruses.

    PubMed Central

    Booth, J. C.; Rweyemamu, M. M.; Pay, T. W.

    1978-01-01

    Two-dimensional quantal microneutralization tests on foot-and-mouth disease viruses, in which neutralizing antibody activity was titrated against a serial range of virus doses, demonstrated a variety of dose-response curves some of which were rectilinear, others clearly curvilinear. Moreover, in the case of the non-linear responses obtained with some antisera, the shape of the curve was such that antibody titres recorded with doses of virus ranging from 10(3)-10(5) TCD50 were closely similar. Studies were carried out on the effect of varying the conditions of the test on the shape of the dose-response curve: significant differences were obtained after treatment of the antiserum-virus mixtures with anti-species globulin, and when the test was assayed in cells of differing susceptibility to infection. PMID:202650

  20. In Situ Monitoring of Particle Consolidation During Low Pressure Cold Spray by Ultrasonic Techniques

    NASA Astrophysics Data System (ADS)

    Maev, R. Gr.; Titov, S.; Leshchynsky, V.; Dzhurinskiy, D.; Lubrick, M.

    2011-06-01

    This study attempts to test the viability of the examination of the cold spray process using acoustic methods, specifically in situ testing during the actual spray process itself. Multiple composites studied by flat and multi-channel transducers as well as the results of actual online measurements are presented. It is shown that the final thickness as well as the dynamics of buildup can be evaluated (including plotting rates of buildup). Cross sections of the coating thickness are also easy to obtain and show true profiles of the coating. The data can also be used to generate real estimates for nozzle speed and spray diameter. Finally, comparisons of real thickness and acoustically estimated thickness show a close linear relationship. The data clearly show that online acoustic measurement is a viable method for estimating thickness buildup.

  1. Relationship Between the Parameters of the Linear and Nonlinear Wave Generation Stages in a Magnetospheric Cyclotron Maser in the Backward-Wave Oscillator Regime

    NASA Astrophysics Data System (ADS)

    Demekhov, A. G.

    2017-03-01

    By using numerical simulations we generalize certain relationships between the parameters of quasimonochromatic whistler-mode waves generated at the linear and nonlinear stages of the cyclotron instability in the backward-wave oscillator regime. One of these relationships is between the wave amplitude at the nonlinear stage and the linear growth rate of the cyclotron instability. It was obtained analytically by V.Yu.Trakhtengerts (1984) for a uniform medium under the assumption of constant frequency and amplitude of the generated wave. We show that a similar relationship also holds for the signals generated in a nonuniform magnetic field and having a discrete structure in the form of short wave packets (elements) with fast frequency drift inside each element. We also generalize the formula for the linear growth rate of absolute cyclotron instability in a nonuniform medium and analyze the relationship between the frequency drift rate in the discrete elements and the wave amplitude. These relationships are important for analyzing the links between the parameters of chorus emissions in the Earth's and planetary magnetospheres and the characteristics of the energetic charged particles generating these signals.

  2. Field measurements of the linear and nonlinear shear moduli of cemented alluvium using dynamically loaded surface footings

    NASA Astrophysics Data System (ADS)

    Park, Kwangsoo

    In this dissertation, a research effort aimed at development and implementation of a direct field test method to evaluate the linear and nonlinear shear modulus of soil is presented. The field method utilizes a surface footing that is dynamically loaded horizontally. The test procedure involves applying static and dynamic loads to the surface footing and measuring the soil response beneath the loaded area using embedded geophones. A wide range in dynamic loads under a constant static load permits measurements of linear and nonlinear shear wave propagation from which shear moduli and associated shearing strains are evaluated. Shear wave velocities in the linear and nonlinear strain ranges are calculated from time delays in waveforms monitored by geophone pairs. Shear moduli are then obtained using the shear wave velocities and the mass density of a soil. Shear strains are determined using particle displacements calculated from particle velocities measured at the geophones by assuming a linear variation between geophone pairs. The field test method was validated by conducting an initial field experiment at sandy site in Austin, Texas. Then, field experiments were performed on cemented alluvium, a complex, hard-to-sample material. Three separate locations at Yucca Mountain, Nevada were tested. The tests successfully measured: (1) the effect of confining pressure on shear and compression moduli in the linear strain range and (2) the effect of strain on shear moduli at various states of stress in the field. The field measurements were first compared with empirical relationships for uncemented gravel. This comparison showed that the alluvium was clearly cemented. The field measurements were then compared to other independent measurements including laboratory resonant column tests and field seismic tests using the spectral-analysis-of-surface-waves method. The results from the field tests were generally in good agreement with the other independent test results, indicating that the proposed method has the ability to directly evaluate complex material like cemented alluvium in the field.

  3. Advanced statistics: linear regression, part I: simple linear regression.

    PubMed

    Marill, Keith A

    2004-01-01

    Simple linear regression is a mathematical technique used to model the relationship between a single independent predictor variable and a single dependent outcome variable. In this, the first of a two-part series exploring concepts in linear regression analysis, the four fundamental assumptions and the mechanics of simple linear regression are reviewed. The most common technique used to derive the regression line, the method of least squares, is described. The reader will be acquainted with other important concepts in simple linear regression, including: variable transformations, dummy variables, relationship to inference testing, and leverage. Simplified clinical examples with small datasets and graphic models are used to illustrate the points. This will provide a foundation for the second article in this series: a discussion of multiple linear regression, in which there are multiple predictor variables.

  4. Genetic programming based quantitative structure-retention relationships for the prediction of Kovats retention indices.

    PubMed

    Goel, Purva; Bapat, Sanket; Vyas, Renu; Tambe, Amruta; Tambe, Sanjeev S

    2015-11-13

    The development of quantitative structure-retention relationships (QSRR) aims at constructing an appropriate linear/nonlinear model for the prediction of the retention behavior (such as Kovats retention index) of a solute on a chromatographic column. Commonly, multi-linear regression and artificial neural networks are used in the QSRR development in the gas chromatography (GC). In this study, an artificial intelligence based data-driven modeling formalism, namely genetic programming (GP), has been introduced for the development of quantitative structure based models predicting Kovats retention indices (KRI). The novelty of the GP formalism is that given an example dataset, it searches and optimizes both the form (structure) and the parameters of an appropriate linear/nonlinear data-fitting model. Thus, it is not necessary to pre-specify the form of the data-fitting model in the GP-based modeling. These models are also less complex, simple to understand, and easy to deploy. The effectiveness of GP in constructing QSRRs has been demonstrated by developing models predicting KRIs of light hydrocarbons (case study-I) and adamantane derivatives (case study-II). In each case study, two-, three- and four-descriptor models have been developed using the KRI data available in the literature. The results of these studies clearly indicate that the GP-based models possess an excellent KRI prediction accuracy and generalization capability. Specifically, the best performing four-descriptor models in both the case studies have yielded high (>0.9) values of the coefficient of determination (R(2)) and low values of root mean squared error (RMSE) and mean absolute percent error (MAPE) for training, test and validation set data. The characteristic feature of this study is that it introduces a practical and an effective GP-based method for developing QSRRs in gas chromatography that can be gainfully utilized for developing other types of data-driven models in chromatography science. Copyright © 2015 Elsevier B.V. All rights reserved.

  5. Relationship status and relationship instability, but not dominance, predict individual differences in baseline cortisol levels.

    PubMed

    Maestripieri, Dario; Klimczuk, Amanda C E; Seneczko, Marianne; Traficonte, Daniel M; Wilson, M Claire

    2013-01-01

    We investigated variation in baseline cortisol levels in relation to relationship status (single or in a relationship), relationship characteristics (length, stability, presence or absence of clear dominance), or individual attributes (dominant or subordinate status, relative physical attractiveness, relationship worries). Study participants were 77 men and 75 women aged between 18 and 38 years. Individuals in romantic relationships had lower cortisol levels than singles. Individuals of African ethnicity, however, showed the opposite pattern. Individuals who perceived their relationship to be highly unstable had higher cortisol levels. Aside from African-Americans, married individuals reported the lowest relationship instability and the lowest cortisol levels, followed by individuals in long-term relationships, and by individuals in short-term relationships. The presence or absence of clear dominance in the relationship, dominance status, or relationship worries did not affect cortisol levels. Therefore relationship status and relationship instability were better predictors of variation in cortisol (presumably through stress-related mechanisms) than individual attributes.

  6. Interpreting the sub-linear Kennicutt-Schmidt relationship: the case for diffuse molecular gas

    NASA Astrophysics Data System (ADS)

    Shetty, Rahul; Clark, Paul C.; Klessen, Ralf S.

    2014-08-01

    Recent statistical analysis of two extragalactic observational surveys strongly indicate a sub-linear Kennicutt-Schmidt (KS) relationship between the star formation rate (ΣSFR) and molecular gas surface density (Σmol). Here, we consider the consequences of these results in the context of common assumptions, as well as observational support for a linear relationship between ΣSFR and the surface density of dense gas. If the CO traced gas depletion time (τ_dep^CO) is constant, and if CO only traces star-forming giant molecular clouds (GMCs), then the physical properties of each GMC must vary, such as the volume densities or star formation rates. Another possibility is that the conversion between CO luminosity and Σmol, the XCO factor, differs from cloud-to-cloud. A more straightforward explanation is that CO permeates the hierarchical interstellar medium, including the filaments and lower density regions within which GMCs are embedded. A number of independent observational results support this description, with the diffuse gas comprising at least 30 per cent of the total molecular content. The CO bright diffuse gas can explain the sub-linear KS relationship, and consequently leads to an increasing τ_dep^CO with Σmol. If ΣSFR linearly correlates with the dense gas surface density, a sub-linear KS relationship indicates that the fraction of diffuse gas fdiff grows with Σmol. In galaxies where Σmol falls towards the outer disc, this description suggests that fdiff also decreases radially.

  7. Functional diversity, succession, and human-mediated disturbances in raised bog vegetation.

    PubMed

    Dyderski, Marcin K; Czapiewska, Natalia; Zajdler, Mateusz; Tyborski, Jarosław; Jagodziński, Andrzej M

    2016-08-15

    Raised and transitional bogs are one of the most threatened types of ecosystem, due to high specialisation of biota, associated with adaptations to severe environmental conditions. The aim of the study was to characterize the relationships between functional diversity (reflecting ecosystem-shaping processes) of raised bog plant communities and successional gradients (expressed as tree dimensions) and to show how impacts of former clear cuts may alter these relationships in two raised bogs in 'Bory Tucholskie' National Park (N Poland). Herbaceous layers of the plant communities were examined by floristic relevés (25m(2)) on systematically established transects. We also assessed patterns of tree ring widths. There were no relationships between vegetation functional diversity components and successional progress: only functional dispersion was negatively, but weakly, correlated with median DBH. Lack of these relationships may be connected with lack of prevalence of habitat filtering and low level of competition over all the successional phases. Former clear cuts, indicated by peaks of tree ring width, influenced the growth of trees in the bogs studied. In the bog with more intensive clear cuts we found more species with higher trophic requirements, which may indicate nutrient influx. However, we did not observe differences in vegetation patterns, functional traits or functional diversity indices between the two bogs studied. We also did not find an influence of clear cut intensity on relationships between functional diversity indices and successional progress. Thus, we found that alteration of the ecosystems studied by neighbourhood clear cuts did not affect the bogs strongly, as the vegetation was resilient to these impacts. Knowledge of vegetation resilience after clear cuts may be crucial for conservation planning in raised bog ecosystems. Copyright © 2016 Elsevier B.V. All rights reserved.

  8. Dilations and the Equation of a Line

    ERIC Educational Resources Information Center

    Yopp, David A.

    2016-01-01

    Students engage in proportional reasoning when they use covariance and multiple comparisons. Without rich connections to proportional reasoning, students may develop inadequate understandings of linear relationships and the equations that model them. Teachers can improve students' understanding of linear relationships by focusing on realistic…

  9. Impact of traffic-related air pollution on acute changes in cardiac autonomic modulation during rest and physical activity: a cross-over study.

    PubMed

    Cole-Hunter, Tom; Weichenthal, Scott; Kubesch, Nadine; Foraster, Maria; Carrasco-Turigas, Glòria; Bouso, Laura; Martínez, David; Westerdahl, Dane; de Nazelle, Audrey; Nieuwenhuijsen, Mark

    2016-01-01

    People are often exposed to traffic-related air pollution (TRAP) during physical activity (PA), but it is not clear if PA modifies the impact of TRAP on cardiac autonomic modulation. We conducted a panel study among 28 healthy adults in Barcelona, Spain to examine how PA may modify the impact of TRAP on cardiac autonomic regulation. Participants completed four 2-h exposure scenarios that included either rest or intermittent exercise in high- and low-traffic environments. Time- and frequency-domain measures of heart rate variability (HRV) were monitored during each exposure period along with continuous measures of TRAP. Linear mixed-effects models were used to estimate the impact of TRAP on HRV as well as potential effect modification by PA. Exposure to TRAP was associated with consistent decreases in HRV; however, exposure-response relationships were not always linear over the broad range of exposures. For example, each 10 μg/m(3) increase in black carbon was associated with a 23% (95% CI: -31, -13) decrease in high frequency power at the low-traffic site, whereas no association was observed at the high-traffic site. PA modified the impact of TRAP on HRV at the high-traffic site and tended to weaken inverse associations with measures reflecting parasympathetic modulation (P ≤ 0.001). Evidence of effect modification at the low-traffic site was less consistent. The strength and direction of the relationship between TRAP and HRV may vary across exposure gradients. PA may modify the impact of TRAP on HRV, particularly at higher concentrations.

  10. TORC3: Token-ring clearing heuristic for currency circulation

    NASA Astrophysics Data System (ADS)

    Humes, Carlos, Jr.; Lauretto, Marcelo S.; Nakano, Fábio; Pereira, Carlos A. B.; Rafare, Guilherme F. G.; Stern, Julio Michael

    2012-10-01

    Clearing algorithms are at the core of modern payment systems, facilitating the settling of multilateral credit messages with (near) minimum transfers of currency. Traditional clearing procedures use batch processing based on MILP - mixed-integer linear programming algorithms. The MILP approach demands intensive computational resources; moreover, it is also vulnerable to operational risks generated by possible defaults during the inter-batch period. This paper presents TORC3 - the Token-Ring Clearing Algorithm for Currency Circulation. In contrast to the MILP approach, TORC3 is a real time heuristic procedure, demanding modest computational resources, and able to completely shield the clearing operation against the participating agents' risk of default.

  11. Linear scaling relationships and volcano plots in homogeneous catalysis – revisiting the Suzuki reaction† †Electronic supplementary information (ESI) available: Detailed derivation of the linear scaling relationships and construction of the volcano plots as well as comparisons of computed values using PBE0-dDsC and M06 functionals is included. See DOI: 10.1039/c5sc02910d Click here for additional data file.

    PubMed Central

    Busch, Michael; Wodrich, Matthew D.

    2015-01-01

    Linear free energy scaling relationships and volcano plots are common tools used to identify potential heterogeneous catalysts for myriad applications. Despite the striking simplicity and predictive power of volcano plots, they remain unknown in homogeneous catalysis. Here, we construct volcano plots to analyze a prototypical reaction from homogeneous catalysis, the Suzuki cross-coupling of olefins. Volcano plots succeed both in discriminating amongst different catalysts and reproducing experimentally known trends, which serves as validation of the model for this proof-of-principle example. These findings indicate that the combination of linear scaling relationships and volcano plots could serve as a valuable methodology for identifying homogeneous catalysts possessing a desired activity through a priori computational screening. PMID:28757966

  12. Application of Statistical Learning Theory to Plankton Image Analysis

    DTIC Science & Technology

    2006-06-01

    linear distance interval from 1 to 40 pixels and two directions formula (horizontal & vertical, and diagonals), EF2 is EF with 7 ex- ponential distance...and four directions formula (horizontal, vertical and two diagonals). It is clear that exponential distance inter- val works better than the linear ...PSI - PS by Vincent, linear and pseudo opening and closing spectra, each has 40 elements, total feature length of 160. PS2 - PS modified from Mei- jster

  13. 77 FR 67427 - Self-Regulatory Organizations; ICE Clear Europe Limited; Notice of Filing of Proposed Rule Change...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-09

    ... would not apply to that relationship. The adoption of the Customer CDS Clearing Model will also require... Customer Clearing Model for CDS Products and To Amend, Clarify and Consolidate Certain Rules and Procedures... provide for a clearing model for CDS products whereby customers of ICE Clear Europe have the ability to...

  14. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Liu, Jian; Guo, Pan; University of Chinese Academy of Sciences, Beijing 100049

    Using molecular dynamics simulations, we show a fine linear relationship between surface energies and microscopic Lennard-Jones parameters of super-hydrophilic surfaces. The linear slope of the super-hydrophilic surfaces is consistent with the linear slope of the super-hydrophobic, hydrophobic, and hydrophilic surfaces where stable water droplets can stand, indicating that there is a universal linear behavior of the surface energies with the water-surface van der Waals interaction that extends from the super-hydrophobic to super-hydrophilic surfaces. Moreover, we find that the linear relationship exists for various substrate types, and the linear slopes of these different types of substrates are dependent on the surfacemore » atom density, i.e., higher surface atom densities correspond to larger linear slopes. These results enrich our understanding of water behavior on solid surfaces, especially the water wetting behaviors on uncharged super-hydrophilic metal surfaces.« less

  15. Testing the dose-response specification in epidemiology: public health and policy consequences for lead.

    PubMed

    Rothenberg, Stephen J; Rothenberg, Jesse C

    2005-09-01

    Statistical evaluation of the dose-response function in lead epidemiology is rarely attempted. Economic evaluation of health benefits of lead reduction usually assumes a linear dose-response function, regardless of the outcome measure used. We reanalyzed a previously published study, an international pooled data set combining data from seven prospective lead studies examining contemporaneous blood lead effect on IQ (intelligence quotient) of 7-year-old children (n = 1,333). We constructed alternative linear multiple regression models with linear blood lead terms (linear-linear dose response) and natural-log-transformed blood lead terms (log-linear dose response). We tested the two lead specifications for nonlinearity in the models, compared the two lead specifications for significantly better fit to the data, and examined the effects of possible residual confounding on the functional form of the dose-response relationship. We found that a log-linear lead-IQ relationship was a significantly better fit than was a linear-linear relationship for IQ (p = 0.009), with little evidence of residual confounding of included model variables. We substituted the log-linear lead-IQ effect in a previously published health benefits model and found that the economic savings due to U.S. population lead decrease between 1976 and 1999 (from 17.1 microg/dL to 2.0 microg/dL) was 2.2 times (319 billion dollars) that calculated using a linear-linear dose-response function (149 billion dollars). The Centers for Disease Control and Prevention action limit of 10 microg/dL for children fails to protect against most damage and economic cost attributable to lead exposure.

  16. Narcissism and newlywed marriage: Partner characteristics and marital trajectories.

    PubMed

    Lavner, Justin A; Lamkin, Joanna; Miller, Joshua D; Campbell, W Keith; Karney, Benjamin R

    2016-04-01

    Despite narcissism's relation with interpersonal dysfunction, surprisingly little empirical research has been devoted to understanding narcissism's effect on intimate relationships in general or marital relationships in particular. The current study addressed this gap using longitudinal data from a community sample of 146 newlywed couples assessed 6 times over the first 4 years of marriage. First, we examined partner characteristics associated with higher levels of narcissism to determine the degree to which couples were matched on narcissism and related traits. Second, we examined how narcissism predicted the trajectory of marital quality over time, testing narcissism's association with initial levels of relationship functioning (the intercept) and changes in relationship functioning (the slope). Results indicated a small degree of homophily but otherwise no clear pattern of partner characteristics for individuals higher in narcissism. Hierarchical linear modeling indicated that wives' total narcissism and entitlement/exploitativeness scores predicted the slope of marital quality over time, including steeper declines in marital satisfaction and steeper increases in marital problems. Husbands' narcissism scores generally had few effects on their own marital quality or that of their wives. These findings are notable in indicating that the effects of personality characteristics on marital functioning may take some time to manifest themselves, even if they were present from early in the marriage. Future research into the mediating psychological and interpersonal processes that link wives' narcissism with poorer marital functioning over time would be valuable. (c) 2016 APA, all rights reserved).

  17. A morphometric comparison of the Namib and southwest Kalahari dunefields using ASTER GDEM data

    NASA Astrophysics Data System (ADS)

    White, Kevin; Bullard, Joanna; Livingstone, Ian; Moran, Lisa

    2015-12-01

    The increased availability of digital elevation models and satellite image data enable testing of morphometric relationships between sand dune variables (dune height, spacing and equivalent sand thickness), which were originally established using limited field survey data. These long-established geomorphological hypotheses can now be tested against very much larger samples than were possible when available data were limited to what could be collected by field surveys alone. This project uses ASTER global digital elevation model (GDEM) data to compare morphometric relationships between sand dune variables in the southwest Kalahari dunefield to those of the Namib sand sea, to test whether the relationships found in an active sand sea (Namib) also hold for the fixed dune system of the nearby southwest Kalahari. The data show significant morphometric differences between the simple linear dunes of the Namib sand sea and the southwest Kalahari; the latter do not show the expected positive relationship between dune height and spacing. The southwest Kalahari dunes show a similar range of dune spacings, but they are less tall, on average, than the Namib sand sea dunes. There is a clear spatial pattern to these morphometric data; the tallest and most closely spaced dunes are towards the southeast of the Kalahari dunefield; and this is where the highest values of equivalent sand thickness result. We consider the possible reasons for the observed differences and highlight the need for more studies comparing sand seas and dunefields from different environmental settings.

  18. A distributed lag approach to fitting non-linear dose-response models in particulate matter air pollution time series investigations.

    PubMed

    Roberts, Steven; Martin, Michael A

    2007-06-01

    The majority of studies that have investigated the relationship between particulate matter (PM) air pollution and mortality have assumed a linear dose-response relationship and have used either a single-day's PM or a 2- or 3-day moving average of PM as the measure of PM exposure. Both of these modeling choices have come under scrutiny in the literature, the linear assumption because it does not allow for non-linearities in the dose-response relationship, and the use of the single- or multi-day moving average PM measure because it does not allow for differential PM-mortality effects spread over time. These two problems have been dealt with on a piecemeal basis with non-linear dose-response models used in some studies and distributed lag models (DLMs) used in others. In this paper, we propose a method for investigating the shape of the PM-mortality dose-response relationship that combines a non-linear dose-response model with a DLM. This combined model will be shown to produce satisfactory estimates of the PM-mortality dose-response relationship in situations where non-linear dose response models and DLMs alone do not; that is, the combined model did not systemically underestimate or overestimate the effect of PM on mortality. The combined model is applied to ten cities in the US and a pooled dose-response model formed. When fitted with a change-point value of 60 microg/m(3), the pooled model provides evidence for a positive association between PM and mortality. The combined model produced larger estimates for the effect of PM on mortality than when using a non-linear dose-response model or a DLM in isolation. For the combined model, the estimated percentage increase in mortality for PM concentrations of 25 and 75 microg/m(3) were 3.3% and 5.4%, respectively. In contrast, the corresponding values from a DLM used in isolation were 1.2% and 3.5%, respectively.

  19. Power of Models in Longitudinal Study: Findings from a Full-Crossed Simulation Design

    ERIC Educational Resources Information Center

    Fang, Hua; Brooks, Gordon P.; Rizzo, Maria L.; Espy, Kimberly Andrews; Barcikowski, Robert S.

    2009-01-01

    Because the power properties of traditional repeated measures and hierarchical multivariate linear models have not been clearly determined in the balanced design for longitudinal studies in the literature, the authors present a power comparison study of traditional repeated measures and hierarchical multivariate linear models under 3…

  20. Towards a definition of biological corridor

    Treesearch

    D.K. Rosenberg; B.R. Noon; E.C. Meslow

    1995-01-01

    Lack of clear, unambiguous criteria that distinguishes a linear habitat patch as a corridor contributes to controversy over the value of corridors for wildlife conservation. The definitions of biological corridors have been vague or inconsistent, and often they confound form and function. Explicit criteria that can differentiate between a linear habitat patch and a...

  1. 78 FR 28680 - Self-Regulatory Organizations; ICE Clear Europe Limited; Notice of Filing and Immediate...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-15

    ...-Regulatory Organizations; ICE Clear Europe Limited; Notice of Filing and Immediate Effectiveness of Proposed Rule Change To Amend Delivery Procedures To Reflect the Clearing Relationship for ICE Futures Europe... Rule 19b-4 thereunder,\\2\\ notice is hereby given that on April 24, 2013, ICE Clear Europe Limited...

  2. Evaluation of force-velocity and power-velocity relationship of arm muscles.

    PubMed

    Sreckovic, Sreten; Cuk, Ivan; Djuric, Sasa; Nedeljkovic, Aleksandar; Mirkov, Dragan; Jaric, Slobodan

    2015-08-01

    A number of recent studies have revealed an approximately linear force-velocity (F-V) and, consequently, a parabolic power-velocity (P-V) relationship of multi-joint tasks. However, the measurement characteristics of their parameters have been neglected, particularly those regarding arm muscles, which could be a problem for using the linear F-V model in both research and routine testing. Therefore, the aims of the present study were to evaluate the strength, shape, reliability, and concurrent validity of the F-V relationship of arm muscles. Twelve healthy participants performed maximum bench press throws against loads ranging from 20 to 70 % of their maximum strength, and linear regression model was applied on the obtained range of F and V data. One-repetition maximum bench press and medicine ball throw tests were also conducted. The observed individual F-V relationships were exceptionally strong (r = 0.96-0.99; all P < 0.05) and fairly linear, although it remains unresolved whether a polynomial fit could provide even stronger relationships. The reliability of parameters obtained from the linear F-V regressions proved to be mainly high (ICC > 0.80), while their concurrent validity regarding directly measured F, P, and V ranged from high (for maximum F) to medium-to-low (for maximum P and V). The findings add to the evidence that the linear F-V and, consequently, parabolic P-V models could be used to study the mechanical properties of muscular systems, as well as to design a relatively simple, reliable, and ecologically valid routine test of the muscle ability of force, power, and velocity production.

  3. Biomass Stoves and Lens Opacity and Cataract in Nepalese Women

    PubMed Central

    Pokhrel, Amod K.; Bates, Michael N.; Shrestha, Sachet P.; Bailey, Ian L.; DiMartino, Robert B.; Smith, Kirk R.; Joshi, N. D.

    2014-01-01

    Purpose Cataract is the most prevalent cause of blindness in Nepal. Several epidemiologic studies have associated cataracts with use of biomass cookstoves. These studies, however, have had limitations, including potential control selection bias and limited adjustment for possible confounding. This study, in Pokhara city, in an area of Nepal where biomass cookstoves are widely used without direct venting of the smoke to the outdoors, focuses on pre-clinical measures of opacity, while avoiding selection bias and taking into account comprehensive data on potential confounding factors Methods Using a cross-sectional study design, severity of lenticular damage, judged on the LOCS III scales, was investigated in females (n=143), aged 20-65 years, without previously diagnosed cataract. Linear and logistic regression analyses were used to examine the relationships with stove type and length of use. Clinically significant cataract, used in the logistic regression models, was defined as a LOCS III score > 2. Results Using gas cookstoves as the reference group, logistic regression analysis for nuclear cataract showed the evidence of relationships with stove type: for biomass stoves, the odds ratio (OR) was 2.58 (95% confidence interval [CI]: 1.22-5.46) and, for kerosene stoves, the OR was 5.18 (95% CI: 0.88-30.38). Similar results were found for nuclear color (LOCS III score > 2), but no association was found with cortical cataracts. Supporting a relationship between biomass stoves and nuclear cataract was a trend with years of exposure to biomass cookstoves (p=0.01). Linear regression analyses did not show clear evidence of an association between lenticular damage and stove types. Biomass fuel used for heating was not associated with any form of opacity. Conclusions This study provides support for associations of biomass and kerosene cookstoves with nuclear opacity and change in nuclear color. The novel associations with kerosene cookstove use deserve further investigation. PMID:23400024

  4. Bark Beetles Modify the Impact of Snow Drought on Remotely Sensed Forest Productivity in the Southern Rocky Mountains, USA

    NASA Astrophysics Data System (ADS)

    Knowles, J. F.; Lestak, L.; Molotch, N. P.

    2016-12-01

    We evaluated the long term (1989-2012) relationship between the satellite-observed Normalized Difference Vegetation Index (NDVI), snowpack accumulation, and atmospheric demand throughout the Southern Rocky Mountain Ecoregion, USA. Deviations from this relationship were further explored during pre- and post-disturbance conditions associated with bark beetles and drought. Over the entire study area, both the snow water equivalent (SWE) and a snow aridity index (SAI), which used the SWE to normalize potential evapotranspiration (PET), were significant predictors of the long-term AVHRR NDVI, but the SAI was a better predictor of NDVI relative to SWE regardless of disturbance. Since these relationships were weaker in disturbed areas, we also introduced a metric of tree mortality, and subsequent multiple linear regression of SAI and cumulative mortality best predicted the NDVI from a pair of heavily impacted focus areas within the larger study area. The post-disturbance NDVI was systematically reduced per unit SAI in these areas, and the difference between the observed and predicted (from pre-disturbance regressions) post-disturbance NDVI was significantly correlated with the cumulative forest mortality. At the Ecoregion scale, these disturbance effects were not clearly evident, and we attribute this to spatial variability of both SAI and NDVI throughout the large study area as evidenced by spatial analysis of Moderate Resolution Imaging Spectroradiometer (MODIS)-derived data. These results constrain the expected reduction in forest productivity due to disturbance and demonstrate that this reduction can be particularly evident during drought conditions resultant from low snow accumulation during the winter. Hence, terrestrial carbon uptake may decrease non-linearly post disturbance. This work has implications for predicting the ecohydrological response to climate change in the southern Rocky Mountains, as reductions in SWE and increases in PET are predicted for this area in the future, and therefore changes in the terrestrial carbon, water, and energy cycles should be expected.

  5. Glycated haemoglobin (HbA1c ) and fasting plasma glucose relationships in sea-level and high-altitude settings.

    PubMed

    Bazo-Alvarez, J C; Quispe, R; Pillay, T D; Bernabé-Ortiz, A; Smeeth, L; Checkley, W; Gilman, R H; Málaga, G; Miranda, J J

    2017-06-01

    Higher haemoglobin levels and differences in glucose metabolism have been reported among high-altitude residents, which may influence the diagnostic performance of HbA 1c . This study explores the relationship between HbA 1c and fasting plasma glucose (FPG) in populations living at sea level and at an altitude of > 3000 m. Data from 3613 Peruvian adults without a known diagnosis of diabetes from sea-level and high-altitude settings were evaluated. Linear, quadratic and cubic regression models were performed adjusting for potential confounders. Receiver operating characteristic (ROC) curves were constructed and concordance between HbA 1c and FPG was assessed using a Kappa index. At sea level and high altitude, means were 13.5 and 16.7 g/dl (P > 0.05) for haemoglobin level; 41 and 40 mmol/mol (5.9% and 5.8%; P < 0.01) for HbA 1c ; and 5.8 and 5.1 mmol/l (105 and 91.3 mg/dl; P < 0.001) for FPG, respectively. The adjusted relationship between HbA 1c and FPG was quadratic at sea level and linear at high altitude. Adjusted models showed that, to predict an HbA 1c value of 48 mmol/mol (6.5%), the corresponding mean FPG values at sea level and high altitude were 6.6 and 14.8 mmol/l (120 and 266 mg/dl), respectively. An HbA 1c cut-off of 48 mmol/mol (6.5%) had a sensitivity for high FPG of 87.3% (95% confidence interval (95% CI) 76.5 to 94.4) at sea level and 40.9% (95% CI 20.7 to 63.6) at high altitude. The relationship between HbA 1c and FPG is less clear at high altitude than at sea level. Caution is warranted when using HbA 1c to diagnose diabetes mellitus in this setting. © 2017 The Authors. Diabetic Medicine published by John Wiley & Sons Ltd on behalf of Diabetes UK.

  6. A reappraisal of the quantitative relationship between sugar intake and dental caries: the need for new criteria for developing goals for sugar intake.

    PubMed

    Sheiham, Aubrey; James, W Philip T

    2014-09-16

    There is a clear relation between sugars and caries. However, no analysis has yet been made of the lifetime burden of caries induced by sugar to see whether the WHO goal of 10% level is optimum and compatible with low levels of caries. The objective of this study was to re-examine the dose-response and quantitative relationship between sugar intake and the incidence of dental caries and to see whether the WHO goal for sugar intake of 10% of energy intake (E) is optimum for low levels of caries in children and adults. Analyses focused on countries where sugar intakes changed because of wartime restrictions or as part of the nutritional transition. A re-analysis of the dose-response relation between dietary sugar and caries incidence in teeth with different levels of susceptibility to dental caries in nationally representative samples of Japanese children. The impact of fluoride on levels of caries was also assessed. Meticulous Japanese data on caries incidence in two types of teeth show robust log-linear relationships to sugar intakes from 0%E to 10%E sugar with a 10 fold increase in caries if caries is assessed over several years' exposure to sugar rather than only for the first year after tooth eruption. Adults aged 65 years and older living in water fluoridated areas where high proportions of people used fluoridated toothpastes, had nearly half of all tooth surfaces affected by caries. This more extensive burden of disease in adults does not occur if sugar intakes are limited to <3% energy intake. There is a robust log-linear relationship of caries to sugar intakes from 0%E to 10%E sugar. A 10%E sugar intake induces a costly burden of caries. These findings imply that public health goals need to set sugar intakes ideally <3%E with <5%E as a pragmatic goal, even when fluoride is widely used. Adult as well as children's caries burdens should define the new criteria for developing goals for sugar intake.

  7. Effects of the approximations of light propagation on quantitative photoacoustic tomography using two-dimensional photon diffusion equation and linearization

    NASA Astrophysics Data System (ADS)

    Okawa, Shinpei; Hirasawa, Takeshi; Kushibiki, Toshihiro; Ishihara, Miya

    2017-12-01

    Quantitative photoacoustic tomography (QPAT) employing a light propagation model will play an important role in medical diagnoses by quantifying the concentration of hemoglobin or a contrast agent. However, QPAT by the light propagation model with the three-dimensional (3D) radiative transfer equation (RTE) requires a huge computational load in the iterative forward calculations involved in the updating process to reconstruct the absorption coefficient. The approximations of the light propagation improve the efficiency of the image reconstruction for the QPAT. In this study, we compared the 3D/two-dimensional (2D) photon diffusion equation (PDE) approximating 3D RTE with the Monte Carlo simulation based on 3D RTE. Then, the errors in a 2D PDE-based linearized image reconstruction caused by the approximations were quantitatively demonstrated and discussed in the numerical simulations. It was clearly observed that the approximations affected the reconstructed absorption coefficient. The 2D PDE-based linearized algorithm succeeded in the image reconstruction of the region with a large absorption coefficient in the 3D phantom. The value reconstructed in the phantom experiment agreed with that in the numerical simulation, so that it was validated that the numerical simulation of the image reconstruction predicted the relationship between the true absorption coefficient of the target in the 3D medium and the reconstructed value with the 2D PDE-based linearized algorithm. Moreover, the the true absorption coefficient in 3D medium was estimated from the 2D reconstructed image on the basis of the prediction by the numerical simulation. The estimation was successful in the phantom experiment, although some limitations were revealed.

  8. Changes in Cirrus Cloudiness and their Relationship to Contrails

    NASA Technical Reports Server (NTRS)

    Minnis, Patrick; Ayers, J. Kirk; Palikonda, Rabindra; Doelling, David R.; Schumann, Ulrich; Gierens, Klaus

    2001-01-01

    Condensation trails, or contrails, formed in the wake of high-altitude aircraft have long been suspected of causing the formation of additional cirrus cloud cover. More cirrus is possible because 10 - 20% of the atmosphere at typical commercial flight altitudes is clear but ice-saturated. Since they can affect the radiation budget like natural cirrus clouds of equivalent optical depth and microphysical properties, contrail -generated cirrus clouds are another potential source of anthropogenic influence on climate. Initial estimates of contrail radiative forcing (CRF) were based on linear contrail coverage and optical depths derived from a limited number of satellite observations. Assuming that such estimates are accurate, they can be considered as the minimum possible CRF because contrails often develop into cirrus clouds unrecognizable as contrails. These anthropogenic cirrus are not likely to be identified as contrails from satellites and would, therefore, not contribute to estimates of contrail coverage. The mean lifetime and coverage of spreading contrails relative to linear contrails are needed to fully assess the climatic effect of contrails, but are difficult to measure directly. However, the maximum possible impact can be estimated using the relative trends in cirrus coverage over regions with and without air traffic. In this paper, the upper bound of CRF is derived by first computing the change in cirrus coverage over areas with heavy air traffic relative to that over the remainder of the globe assuming that the difference between the two trends is due solely to contrails. This difference is normalized to the corresponding linear contrail coverage for the same regions to obtain an average spreading factor. The maximum contrail-cirrus coverage, estimated as the product of the spreading factor and the linear contrail coverage, is then used in the radiative model to estimate the maximum potential CRF for current air traffic.

  9. Determination of water depth with high-resolution satellite imagery over variable bottom types

    USGS Publications Warehouse

    Stumpf, Richard P.; Holderied, Kristine; Sinclair, Mark

    2003-01-01

    A standard algorithm for determining depth in clear water from passive sensors exists; but it requires tuning of five parameters and does not retrieve depths where the bottom has an extremely low albedo. To address these issues, we developed an empirical solution using a ratio of reflectances that has only two tunable parameters and can be applied to low-albedo features. The two algorithms--the standard linear transform and the new ratio transform--were compared through analysis of IKONOS satellite imagery against lidar bathymetry. The coefficients for the ratio algorithm were tuned manually to a few depths from a nautical chart, yet performed as well as the linear algorithm tuned using multiple linear regression against the lidar. Both algorithms compensate for variable bottom type and albedo (sand, pavement, algae, coral) and retrieve bathymetry in water depths of less than 10-15 m. However, the linear transform does not distinguish depths >15 m and is more subject to variability across the studied atolls. The ratio transform can, in clear water, retrieve depths in >25 m of water and shows greater stability between different areas. It also performs slightly better in scattering turbidity than the linear transform. The ratio algorithm is somewhat noisier and cannot always adequately resolve fine morphology (structures smaller than 4-5 pixels) in water depths >15-20 m. In general, the ratio transform is more robust than the linear transform.

  10. Detection of Carbendazim Residues with a Colorimetric Sensor Based on Gold Nanoparticles

    NASA Astrophysics Data System (ADS)

    Ma, Y.; Jiang, H.; Shen, C.; Hou, Ch.; Huo, D.; Wu, H.; Yang, M.

    2017-07-01

    Carbendazim is among the most popular benzimidazole bactericides that are widely used to boost food production, and its residue poses a great threat to human health and the environment. In this paper, we presented a colorimetric sensor based on gold nanoparticles (Au-NPs) for the detection of carbendazim residues. The Au-NPs were stabilized by citric acid synthesized by chloroauric acid and sodium citrate with a diameter of about 13 nm. Upon reaction with carbendazim, the sensor gave a clear color change that could be distinguished with the naked eye. Thus we elaborated a new method for rapid determination of this benzimidazole bactericide. After optimization of the detection conditions, the sensor showed a very good linear relationship with the carbendazim concentrations varying from 10 to 600 ppb with a detection limit down to 3.4 ppb (S/N = 3). These preliminary results demonstrate that the presented sensor is promising for fast carbendazim analysis.

  11. An Experimental Investigation of Mechanical Properties in Clay Brick Masonry by Partial Replacement of Fine Aggregate with Clay Brick Waste

    NASA Astrophysics Data System (ADS)

    Kumavat, Hemraj Ramdas

    2016-09-01

    The compressive stress-strain behavior and mechanical properties of clay brick masonry and its constituents clay bricks and mortar, have been studied by several laboratory tests. Using linear regression analysis, a analytical model has been proposed for obtaining the stress-strain curves for masonry that can be used in the analysis and design procedures. The model requires only the compressive strengths of bricks and mortar as input data, which can be easily obtained experimentally. Development of analytical model from the obtained experimental results of Young's modulus and compressive strength. Simple relationships have been identified for obtaining the modulus of elasticity of bricks, mortar, and masonry from their corresponding compressive strengths. It was observed that the proposed analytical model clearly demonstrates a reasonably good prediction of the stress-strain curves when compared with the experimental curves.

  12. Fabrication of Amperometric Glucose Sensor Using Glucose Oxidase-Cellulose Nanofiber Aqueous Solution.

    PubMed

    Yasuzawa, Mikito; Omura, Yuya; Hiura, Kentaro; Li, Jiang; Fuchiwaki, Yusuke; Tanaka, Masato

    2015-01-01

    Cellulose nanofiber aqueous solution, which remained virtually transparent for more than one week, was prepared by using the clear upper layer of diluted cellulose nanofiber solution produced by wet jet milling. Glucose oxidase (GOx) was easily dissolved in this solution and GOx-immobilized electrode was easily fabricated by simple repetitious drops of GOx-cellulose solution on the surface of a platinum-iridium electrode. Glucose sensor properties of the obtained electrodes were examined in phosphate buffer solution of pH 7.4 at 40°C. The obtained electrode provided a glucose sensor response with significantly high response speed and good linear relationship between glucose concentration and response current. After an initial decrease of response sensitivity for a few days, relatively constant sensitivity was obtained for about 20 days. Nevertheless, the influence of electroactive compounds such as ascorbic acid, uric acid and acetoaminophen were not negletable.

  13. Slip and frictional heating of extruded polyethylene melts

    NASA Astrophysics Data System (ADS)

    Pérez-González, José; Marín-Santibáñez, Benjamín M.; Zamora-López, Héctor S.; Rodríguez-González, Francisco

    2017-05-01

    Extrusion of polymer melts with slip at the die generates frictional heating. The relationship between slip flow and frictional heating during the continuous extrusion of a non-slipping linear low-density (LLDPE) and a slipping high-density polyethylene (HDPE), respectively, both pure as well as blended with a fluoropolymer processing aid (PA), was investigated in this work by Rheo-particle image velocimetry and thermal imaging. Significant rises in temperature were measured under slip and no slip conditions, being these much higher than the values predicted by the adiabatic flow assumption. Clear difference was made between viscous and frictional heating before the stick-slip regime for the LLDPE, even though they could not be distinguished from one another at higher stresses. Such a difference, however, could not be made for the slipping HDPE, since overall in the presence of slip, frictional and viscous heating act synergistically to increase the melt temperature.

  14. Application of alkyne-TCNQ addition reaction to polymerization.

    PubMed

    Washino, Yusuke; Michinobu, Tsuyoshi

    2011-04-19

    The polymerization using a high-yielding addition reaction between electron-rich alkynes and 7,7,8,8-tetracyanoquinodimethane (TCNQ) derivatives is described. The bifunctional monomer containing two TCNQ moieties and the counter comonomer bearing two dialkylaniline (DAA)-substituted alkynes are reacted in 1,2-dichloroethane under mild heating conditions. At the high monomer concentrations, high molecular weight linear polymers are obtained, while the reaction at the low monomer concentrations produces a significant amount of the cyclic compounds. A clear relationship between the monomer concentration and the cyclic compound amount is demonstrated. The obtained polymers feature a sufficient thermal stability with the decomposition temperature exceeding 300  °C as well as strong charge-transfer (CT) bands and redox activities ascribed to the produced donor-acceptor moieties. These features are also used to optimize the polymerization conditions and to estimate the chemical structures. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  15. An empirical evaluation of genetic distance statistics using microsatellite data from bear (Ursidae) populations.

    PubMed

    Paetkau, D; Waits, L P; Clarkson, P L; Craighead, L; Strobeck, C

    1997-12-01

    A large microsatellite data set from three species of bear (Ursidae) was used to empirically test the performance of six genetic distance measures in resolving relationships at a variety of scales ranging from adjacent areas in a continuous distribution to species that diverged several million years ago. At the finest scale, while some distance measures performed extremely well, statistics developed specifically to accommodate the mutational processes of microsatellites performed relatively poorly, presumably because of the relatively higher variance of these statistics. At the other extreme, no statistic was able to resolve the close sister relationship of polar bears and brown bears from more distantly related pairs of species. This failure is most likely due to constraints on allele distributions at microsatellite loci. At intermediate scales, both within continuous distributions and in comparisons to insular populations of late Pleistocene origin, it was not possible to define the point where linearity was lost for each of the statistics, except that it is clearly lost after relatively short periods of independent evolution. All of the statistics were affected by the amount of genetic diversity within the populations being compared, significantly complicating the interpretation of genetic distance data.

  16. An Empirical Evaluation of Genetic Distance Statistics Using Microsatellite Data from Bear (Ursidae) Populations

    PubMed Central

    Paetkau, D.; Waits, L. P.; Clarkson, P. L.; Craighead, L.; Strobeck, C.

    1997-01-01

    A large microsatellite data set from three species of bear (Ursidae) was used to empirically test the performance of six genetic distance measures in resolving relationships at a variety of scales ranging from adjacent areas in a continuous distribution to species that diverged several million years ago. At the finest scale, while some distance measures performed extremely well, statistics developed specifically to accommodate the mutational processes of microsatellites performed relatively poorly, presumably because of the relatively higher variance of these statistics. At the other extreme, no statistic was able to resolve the close sister relationship of polar bears and brown bears from more distantly related pairs of species. This failure is most likely due to constraints on allele distributions at microsatellite loci. At intermediate scales, both within continuous distributions and in comparisons to insular populations of late Pleistocene origin, it was not possible to define the point where linearity was lost for each of the statistics, except that it is clearly lost after relatively short periods of independent evolution. All of the statistics were affected by the amount of genetic diversity within the populations being compared, significantly complicating the interpretation of genetic distance data. PMID:9409849

  17. Associations between aerobic and muscular fitness and cardiovascular disease risk: the northern Ireland young hearts study.

    PubMed

    Hoekstra, Trynke; Boreham, Colin A; Murray, Liam J; Twisk, Jos W R

    2008-11-01

    It is not clear what the relative contribution is of specific components of physical fitness (aerobic and muscular) to cardiovascular disease (CVD) risk. We investigated associations between aerobic fitness (endurance) and muscular fitness (power) and CVD risk factors. Data were obtained from the Young Hearts project, a representative sample of 12- and 15-year-old boys and girls from Northern Ireland (N = 2016). Aerobic fitness was determined by the 20-m shuttle run test, muscular fitness by the Sargent jump test. CVD risk factors included sum of skinfolds, systolic and diastolic blood pressure, serum total cholesterol (TC), HDL cholesterol, and TC:HDL ratio. Several linear regression analyses were conducted for 4 age and gender groups separately, with the risk factor as the outcome variable. Significant associations between aerobic fitness and a healthy CVD risk profile were found. These observed relationships were independent of power, whereas the (few) relationships between muscular fitness and the risk factors were partly explained by endurance. Tailored, preventive strategies during adolescence, incorporating endurance rather than power sports, could be encouraged to help prevent CVD. This is important because existing studies propose that healthiness during adulthood is founded on healthiness in adolescence.

  18. Risks associated with communication delays in infants from underserved South African communities.

    PubMed

    van der Linde, Jeannie; Swanepoel, De Wet; Glascoe, Frances P; Louw, E M; Hugo, Jannie F M; Vinck, Bart

    2015-01-01

    For optimal development young children need warm, responsive, enriched and communicative environments for learning social, language, and other skills. Infants and toddlers exposed to psychosocial risk lack enriched environments and may present with communication delays. To investigate the relationship between psychosocial risks and communication delays in infants from underserved communities in South Africa. Primary healthcare facilities in Tshwane district, South Africa. A parent interview and Rossetti Infant Toddler Language Scales were used to collect data from caregivers of 201 infants aged 6–12 months, selected through convenience sampling. Associations between communication delays and risks were determined (Chi-square and Fisher's exact tests). A log-linear model analysis was used to model the simultaneous effect of significant risks on the probability of having communication delays. Communication delays were present in 13% of infants. Infants with two or more siblings, born from mothers aged 18–29 years who own their house, had a 39% chance of presenting with communication delays. Developmental screening and early intervention is important in primary healthcare contexts in South Africa, as a clear relationship has been established between three risk factors and communication delays in infants.

  19. Quantitative structure-property relationship analysis for the retention index of fragrance-like compounds on a polar stationary phase.

    PubMed

    Rojas, Cristian; Duchowicz, Pablo R; Tripaldi, Piercosimo; Pis Diez, Reinaldo

    2015-11-27

    A quantitative structure-property relationship (QSPR) was developed for modeling the retention index of 1184 flavor and fragrance compounds measured using a Carbowax 20M glass capillary gas chromatography column. The 4885 molecular descriptors were calculated using Dragon software, and then were simultaneously analyzed through multivariable linear regression analysis using the replacement method (RM) variable subset selection technique. We proceeded in three steps, the first one by considering all descriptor blocks, the second one by excluding conformational descriptor blocks, and the last one by analyzing only 3D-descriptor families. The models were validated through an external test set of compounds. Cross-validation methods such as leave-one-out and leave-many-out were applied, together with Y-randomization and applicability domain analysis. The developed model was used to estimate the I of a set of 22 molecules. The results clearly suggest that 3D-descriptors do not offer relevant information for modeling the retention index, while a topological index such as the Randić-like index from reciprocal squared distance matrix has a high relevance for this purpose. Copyright © 2015 Elsevier B.V. All rights reserved.

  20. 77 FR 76315 - Self-Regulatory Organizations; ICE Clear Europe Limited; Notice of Filing and Immediate...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-27

    ...-Regulatory Organizations; ICE Clear Europe Limited; Notice of Filing and Immediate Effectiveness of Proposed Rule Change to Delivery Procedures To Reflect the Clearing Relationship for ICE Futures U.S. Inc... Rule 19b-4 thereunder,\\2\\ notice is hereby given that on December 19, 2012, ICE Clear Europe Limited...

  1. Threat Appeals: The Fear-Persuasion Relationship is Linear and Curvilinear.

    PubMed

    Dillard, James Price; Li, Ruobing; Huang, Yan

    2017-11-01

    Drive theory may be seen as the first scientific theory of health and risk communication. However, its prediction of a curvilinear association between fear and persuasion is generally held to be incorrect. A close rereading of Hovland et al. reveals that within- and between-persons processes were conflated. Using a message that advocated obtaining a screening for colonoscopy, this study (N = 259) tested both forms of the inverted-U hypothesis. In the between-persons data, analyses revealed a linear effect that was consistent with earlier investigations. However, the data showed an inverted-U relationship in within-persons data. Hence, the relationship between fear and persuasion is linear or curvilinear depending on the level of analysis.

  2. Linear scaling relationships and volcano plots in homogeneous catalysis - revisiting the Suzuki reaction.

    PubMed

    Busch, Michael; Wodrich, Matthew D; Corminboeuf, Clémence

    2015-12-01

    Linear free energy scaling relationships and volcano plots are common tools used to identify potential heterogeneous catalysts for myriad applications. Despite the striking simplicity and predictive power of volcano plots, they remain unknown in homogeneous catalysis. Here, we construct volcano plots to analyze a prototypical reaction from homogeneous catalysis, the Suzuki cross-coupling of olefins. Volcano plots succeed both in discriminating amongst different catalysts and reproducing experimentally known trends, which serves as validation of the model for this proof-of-principle example. These findings indicate that the combination of linear scaling relationships and volcano plots could serve as a valuable methodology for identifying homogeneous catalysts possessing a desired activity through a priori computational screening.

  3. Evidence for Natural Selection in Nucleotide Content Relationships Based on Complete Mitochondrial Genomes: Strong Effect of Guanine Content on Separation between Terrestrial and Aquatic Vertebrates.

    PubMed

    Sorimachi, Kenji; Okayasu, Teiji

    2015-01-01

    The complete vertebrate mitochondrial genome consists of 13 coding genes. We used this genome to investigate the existence of natural selection in vertebrate evolution. From the complete mitochondrial genomes, we predicted nucleotide contents and then separated these values into coding and non-coding regions. When nucleotide contents of a coding or non-coding region were plotted against the nucleotide content of the complete mitochondrial genomes, we obtained linear regression lines only between homonucleotides and their analogs. On every plot using G or A content purine, G content in aquatic vertebrates was higher than that in terrestrial vertebrates, while A content in aquatic vertebrates was lower than that in terrestrial vertebrates. Based on these relationships, vertebrates were separated into two groups, terrestrial and aquatic. However, using C or T content pyrimidine, clear separation between these two groups was not obtained. The hagfish (Eptatretus burgeri) was further separated from both terrestrial and aquatic vertebrates. Based on these results, nucleotide content relationships predicted from the complete vertebrate mitochondrial genomes reveal the existence of natural selection based on evolutionary separation between terrestrial and aquatic vertebrate groups. In addition, we propose that separation of the two groups might be linked to ammonia detoxification based on high G and low A contents, which encode Glu rich and Lys poor proteins.

  4. Educational Resistance in a Runaway World: Poetic Meditations on Power and Surveillance

    ERIC Educational Resources Information Center

    Corbett, Michael

    2008-01-01

    It is becoming clear that standard, linear solutions to the problems of resistant children are problematic because they imagine a world of schooling in which place and power do not matter. Poetry can challenge the typically linear, prescriptive, and modernist assumptions that are central to much educational theory and practice. In this article,…

  5. Assessment of the relationship between chlorophyll fluorescence and photosynthesis across scales from measurements and simulations

    NASA Astrophysics Data System (ADS)

    Zhang, Y.; Guanter, L.; Berry, J. A.; Tol, C. V. D.

    2016-12-01

    Solar-induced chlorophyll fluorescence (SIF) is a novel optical tool for assessment of terrestrial photosynthesis (GPP). Recent work have shown the strong link between GPP and satellite retrievals of SIF at broad scales. However, critical gaps remain between short term small-scale mechanistic understanding and seasonal global observations. In this presentation, we provide a model-based analysis of the relationship between SIF and GPP across scales for diverse vegetation types and a range of meteorological conditions, with the ultimate focus on reproducing the environmental conditions during remote sensing measurements. The coupled fluorescence-photosynthesis model SCOPE is used to simulate GPP and SIF at the both leaf and canopy levels for 13 flux sites. Analyses were conducted to investigate the effects of temporal scaling, canopy structure, overpass time, and spectral domain on the relationship between SIF and GPP. The simulated SIF is highly non-linear with GPP at the leaf level and instantaneous time scale and tends to linearize when scaling to the canopy level and daily to seasonal scales. These relationships are consistent across a wide range of vegetation types. The relationship between SIF and GPP is primarily driven by absorbed photosynthetically active radiation (APAR), especially at the seasonal scale, although the photosynthetic efficiency also contributes to strengthen the link between them. The linearization of their relationship from leaf to canopy and averaging over time is because the overall conditions of the canopy fall within the range of the linear responses of GPP and SIF to light and the photosynthetic capacity. Our results further show that the top-of-canopy relationships between simulated SIF and GPP have similar linearity regardless of whether we used the morning or midday satellite overpass times. These findings are confirmed by field measurements. In addition, the simulated red SIF at 685 nm has a similar relationship with GPP as that of far-red SIF at 740 nm at the canopy level.

  6. Image defog algorithm based on open close filter and gradient domain recursive bilateral filter

    NASA Astrophysics Data System (ADS)

    Liu, Daqian; Liu, Wanjun; Zhao, Qingguo; Fei, Bowen

    2017-11-01

    To solve the problems of fuzzy details, color distortion, low brightness of the image obtained by the dark channel prior defog algorithm, an image defog algorithm based on open close filter and gradient domain recursive bilateral filter, referred to as OCRBF, was put forward. The algorithm named OCRBF firstly makes use of weighted quad tree to obtain more accurate the global atmospheric value, then exploits multiple-structure element morphological open and close filter towards the minimum channel map to obtain a rough scattering map by dark channel prior, makes use of variogram to correct the transmittance map,and uses gradient domain recursive bilateral filter for the smooth operation, finally gets recovery images by image degradation model, and makes contrast adjustment to get bright, clear and no fog image. A large number of experimental results show that the proposed defog method in this paper can be good to remove the fog , recover color and definition of the fog image containing close range image, image perspective, the image including the bright areas very well, compared with other image defog algorithms,obtain more clear and natural fog free images with details of higher visibility, what's more, the relationship between the time complexity of SIDA algorithm and the number of image pixels is a linear correlation.

  7. Competition Experiments as a Means of Evaluating Linear Free Energy Relationships

    ERIC Educational Resources Information Center

    Mullins, Richard J.; Vedernikov, Andrei; Viswanathan, Rajesh

    2004-01-01

    The use of competition experiments as a means of evaluating linear free energy relationship in the undergraduate teaching laboratory is reported. The use of competition experiments proved to be a reliable method for the construction of Hammett plots with good correlation providing great flexibility with regard to the compounds and reactions that…

  8. Looking for Connections between Linear and Exponential Functions

    ERIC Educational Resources Information Center

    Lo, Jane-Jane; Kratky, James L.

    2012-01-01

    Students frequently have difficulty determining whether a given real-life situation is best modeled as a linear relationship or as an exponential relationship. One root of such difficulty is the lack of deep understanding of the very concept of "rate of change." The authors will provide a lesson that allows students to reveal their misconceptions…

  9. Global versus local linear beat-to-beat analysis of the relationship between arterial pressure and pulse transit time during dynamic exercise.

    PubMed

    Porta, A; Gasperi, C; Nollo, G; Lucini, D; Pizzinelli, P; Antolini, R; Pagani, M

    2006-04-01

    Global linear analysis has been traditionally performed to verify the relationship between pulse transit time (PTT) and systolic arterial pressure (SAP) at the level of their spontaneous beat-to-beat variabilities: PTT and SAP have been plotted in the plane (PTT,SAP) and a significant linear correlation has been found. However, this relationship is weak and in specific individuals cannot be found. This result prevents the utilization of the SAP-PTT relationship to derive arterial pressure changes from PTT measures on an individual basis. We propose a local linear approach to study the SAP-PTT relationship. This approach is based on the definition of short SAP-PTT sequences characterized by SAP increase (decrease) and PTT decrease (increase) and on their search in the SAP and PTT beat-to-beat series. This local approach was applied to PTT and SAP series derived from 13 healthy humans during incremental supine dynamic exercise (at 10, 20 and 30% of the nominal individual maximum effort) and compared to the global approach. While global approach failed in some subjects, local analysis allowed the extraction of the gain of the SAP-PTT relationship in all subjects both at rest and during exercise. When both local and global analyses were successful, the local SAP-PTT gain is more negative than the global one as a likely result of noise reduction.

  10. Incorporating nonlinearity into mediation analyses.

    PubMed

    Knafl, George J; Knafl, Kathleen A; Grey, Margaret; Dixon, Jane; Deatrick, Janet A; Gallo, Agatha M

    2017-03-21

    Mediation is an important issue considered in the behavioral, medical, and social sciences. It addresses situations where the effect of a predictor variable X on an outcome variable Y is explained to some extent by an intervening, mediator variable M. Methods for addressing mediation have been available for some time. While these methods continue to undergo refinement, the relationships underlying mediation are commonly treated as linear in the outcome Y, the predictor X, and the mediator M. These relationships, however, can be nonlinear. Methods are needed for assessing when mediation relationships can be treated as linear and for estimating them when they are nonlinear. Existing adaptive regression methods based on fractional polynomials are extended here to address nonlinearity in mediation relationships, but assuming those relationships are monotonic as would be consistent with theories about directionality of such relationships. Example monotonic mediation analyses are provided assessing linear and monotonic mediation of the effect of family functioning (X) on a child's adaptation (Y) to a chronic condition by the difficulty (M) for the family in managing the child's condition. Example moderated monotonic mediation and simulation analyses are also presented. Adaptive methods provide an effective way to incorporate possibly nonlinear monotonicity into mediation relationships.

  11. Profile of High School Students’ Propositional Network Representation when Interpreting Convention Diagrams

    NASA Astrophysics Data System (ADS)

    Fatiha, M.; Rahmat, A.; Solihat, R.

    2017-09-01

    The delivery of concepts in studying Biology often represented through a diagram to easily makes student understand about Biology material. One way to knowing the students’ understanding about diagram can be seen from causal relationship that is constructed by student in the propositional network representation form. This research reveal the trend of students’ propositional network representation patterns when confronted with convention diagram. This descriptive research involved 32 students at one of senior high school in Bandung. The research data was acquired by worksheet that was filled by diagram and it was developed according on information processing standards. The result of this research revealed three propositional network representation patterns are linear relationship, simple reciprocal relationship, and complex reciprocal relationship. The dominating pattern is linear form that is simply connect some information components in diagram by 59,4% students, the reciprocal relationship form with medium level by 28,1% students while the complex reciprocal relationship by only 3,1% and the rest was students who failed to connect information components by 9,4%. Based on results, most of student only able to connect information components on the picture in linear form and a few student constructing reciprocal relationship between information components on convention diagram.

  12. Reinvestigation of the relationship between the amplitude of the first heart sound to cardiac dynamics.

    PubMed

    Tang, Hong; Ruan, Chengjie; Qiu, Tianshuang; Park, Yongwan; Xiao, Shouzhong

    2013-08-01

    The relationships between the amplitude of the first heart sound (S1) and the rising rate of left ventricular pressure (LVP) concluded in previous studies were not consistent. Some researchers believed the relationship was positively linear; others stated the relationship was only positively correlated. To further investigate this relationship, this study simultaneously sampled the external phonocardiogram, electrocardiogram, and intracardiac pressure in the left ventricle in three anesthetized dogs, while invoking wide hemodynamic changes using various doses of epinephrine. The relationship between the maximum amplitude of S1 and the maximum rising rate of LVP and the relationship between the amplitude of dominant peaks/valleys and the corresponding rising rate of LVP were examined by linear, quadratic, cubic, and exponential models. The results showed that the relationships are best fit by nonlinear exponential models.

  13. 3D Pathology Volumetric Technique: A Method for Calculating Breast Tumour Volume from Whole-Mount Serial Section Images

    PubMed Central

    Clarke, G. M.; Murray, M.; Holloway, C. M. B.; Liu, K.; Zubovits, J. T.; Yaffe, M. J.

    2012-01-01

    Tumour size, most commonly measured by maximum linear extent, remains a strong predictor of survival in breast cancer. Tumour volume, proportional to the number of tumour cells, may be a more accurate surrogate for size. We describe a novel “3D pathology volumetric technique” for lumpectomies and compare it with 2D measurements. Volume renderings and total tumour volume are computed from digitized whole-mount serial sections using custom software tools. Results are presented for two lumpectomy specimens selected for tumour features which may challenge accurate measurement of tumour burden with conventional, sampling-based pathology: (1) an infiltrative pattern admixed with normal breast elements; (2) a localized invasive mass separated from the in situ component by benign tissue. Spatial relationships between key features (tumour foci, close or involved margins) are clearly visualized in volume renderings. Invasive tumour burden can be underestimated using conventional pathology, compared to the volumetric technique (infiltrative pattern: 30% underestimation; localized mass: 3% underestimation for invasive tumour, 44% for in situ component). Tumour volume approximated from 2D measurements (i.e., maximum linear extent), assuming elliptical geometry, was seen to overestimate volume compared to the 3D volumetric calculation (by a factor of 7x for the infiltrative pattern; 1.5x for the localized invasive mass). PMID:23320179

  14. Optimal and robust control of a class of nonlinear systems using dynamically re-optimised single network adaptive critic design

    NASA Astrophysics Data System (ADS)

    Tiwari, Shivendra N.; Padhi, Radhakant

    2018-01-01

    Following the philosophy of adaptive optimal control, a neural network-based state feedback optimal control synthesis approach is presented in this paper. First, accounting for a nominal system model, a single network adaptive critic (SNAC) based multi-layered neural network (called as NN1) is synthesised offline. However, another linear-in-weight neural network (called as NN2) is trained online and augmented to NN1 in such a manner that their combined output represent the desired optimal costate for the actual plant. To do this, the nominal model needs to be updated online to adapt to the actual plant, which is done by synthesising yet another linear-in-weight neural network (called as NN3) online. Training of NN3 is done by utilising the error information between the nominal and actual states and carrying out the necessary Lyapunov stability analysis using a Sobolev norm based Lyapunov function. This helps in training NN2 successfully to capture the required optimal relationship. The overall architecture is named as 'Dynamically Re-optimised single network adaptive critic (DR-SNAC)'. Numerical results for two motivating illustrative problems are presented, including comparison studies with closed form solution for one problem, which clearly demonstrate the effectiveness and benefit of the proposed approach.

  15. Between- and within-lake responses of macrophyte richness metrics to shoreline developmen

    USGS Publications Warehouse

    Beck, Marcus W.; Vondracek, Bruce C.; Hatch, Lorin K.

    2013-01-01

    Aquatic habitat in littoral environments can be affected by residential development of shoreline areas. We evaluated the relationship between macrophyte richness metrics and shoreline development to quantify indicator response at 2 spatial scales for Minnesota lakes. First, the response of total, submersed, and sensitive species to shoreline development was evaluated within lakes to quantify macrophyte response as a function of distance to the nearest dock. Within-lake analyses using generalized linear mixed models focused on 3 lakes of comparable size with a minimal influence of watershed land use. Survey points farther from docks had higher total species richness and presence of species sensitive to disturbance. Second, between-lake effects of shoreline development on total, submersed, emergent-floating, and sensitive species were evaluated for 1444 lakes. Generalized linear models were developed for all lakes and stratified subsets to control for lake depth and watershed land use. Between-lake analyses indicated a clear response of macrophyte richness metrics to increasing shoreline development, such that fewer emergent-floating and sensitive species were correlated with increasing density of docks. These trends were particularly evident for deeper lakes with lower watershed development. Our results provide further evidence that shoreline development is associated with degraded aquatic habitat, particularly by illustrating the response of macrophyte richness metrics across multiple lake types and different spatial scales.

  16. Evaluation of systemic markers of inflammation in atomic-bomb survivors with special reference to radiation and age effects.

    PubMed

    Hayashi, Tomonori; Morishita, Yukari; Khattree, Ravindra; Misumi, Munechika; Sasaki, Keiko; Hayashi, Ikue; Yoshida, Kengo; Kajimura, Junko; Kyoizumi, Seishi; Imai, Kazue; Kusunoki, Yoichiro; Nakachi, Kei

    2012-11-01

    Past exposure to atomic bomb (A-bomb) radiation has exerted various long-lasting deleterious effects on the health of survivors. Some of these effects are seen even after >60 yr. In this study, we evaluated the subclinical inflammatory status of 442 A-bomb survivors, in terms of 8 inflammation-related cytokines or markers, comprised of plasma levels of reactive oxygen species (ROS), interleukin (IL)-6, tumor necrosis factor α (TNF-α), C-reactive protein (CRP), IL-4, IL-10, and immunoglobulins, and erythrocyte sedimentation rate (ESR). The effects of past radiation exposure and natural aging on these markers were individually assessed and compared. Next, to assess the biologically significant relationship between inflammation and radiation exposure or aging, which was masked by the interrelationship of those cytokines/markers, we used multivariate statistical analyses and evaluated the systemic markers of inflammation as scores being calculated by linear combinations of selected cytokines and markers. Our results indicate that a linear combination of ROS, IL-6, CRP, and ESR generated a score that was the most indicative of inflammation and revealed clear dependences on radiation dose and aging that were found to be statistically significant. The results suggest that collectively, radiation exposure, in conjunction with natural aging, may enhance the persistent inflammatory status of A-bomb survivors.

  17. Determination of polyhexamethylene biguanide hydrochloride using photometric colloidal titration with crystal violet as a color indicator.

    PubMed

    Masadome, Takashi; Miyanishi, Takaaki; Watanabe, Keita; Ueda, Hiroshi; Hattori, Toshiaki

    2011-01-01

    A solution of polyhexamethylene biguanide hydrochloride (PHMB-HCl) was titrated with a standard solution of potassium poly(vinyl sulfate) (PVSK) using crystal violet (CV) as an photometric indicator cation. The end point was detected by a sharp absorbance change due to an abrupt decrease in the concentration of CV. A linear relationship between the concentration of PHMB-HCl and the end-point volume of the titrant existed in the concentration range from 2 to 10 × 10(-6) eq mol L(-1). Back-titration was based on adding an excess amount of PVSK to a sample solution containing CV, which was titrated with a standard solution of poly(diallyldimethylammonium chloride) (PDADMAC). The calibration curve of the PHMB-HCl concentration to the end point volume of the titrant was also linear in the concentration range from 2 to 8 × 10(-6) eq mol L(-1). Both photometric titrations were applied to the determination of PHMB-HCl in a few contact-lens detergents. Back-titration showed a clear end point, but direct titration showed an unclear end point. The results of the back-titration of PHMB-HCl were compared with the content registered in its labels. 2011 © The Japan Society for Analytical Chemistry

  18. Application of Artificial Neural Networks to the Development of Improved Multi-Sensor Retrievals of Near-Surface Air Temperature and Humidity Over Ocean

    NASA Technical Reports Server (NTRS)

    Roberts, J. Brent; Robertson, Franklin R.; Clayson, Carol Anne

    2012-01-01

    Improved estimates of near-surface air temperature and air humidity are critical to the development of more accurate turbulent surface heat fluxes over the ocean. Recent progress in retrieving these parameters has been made through the application of artificial neural networks (ANN) and the use of multi-sensor passive microwave observations. Details are provided on the development of an improved retrieval algorithm that applies the nonlinear statistical ANN methodology to a set of observations from the Advanced Microwave Scanning Radiometer (AMSR-E) and the Advanced Microwave Sounding Unit (AMSU-A) that are currently available from the NASA AQUA satellite platform. Statistical inversion techniques require an adequate training dataset to properly capture embedded physical relationships. The development of multiple training datasets containing only in-situ observations, only synthetic observations produced using the Community Radiative Transfer Model (CRTM), or a mixture of each is discussed. An intercomparison of results using each training dataset is provided to highlight the relative advantages and disadvantages of each methodology. Particular emphasis will be placed on the development of retrievals in cloudy versus clear-sky conditions. Near-surface air temperature and humidity retrievals using the multi-sensor ANN algorithms are compared to previous linear and non-linear retrieval schemes.

  19. Norisoprenoids, sesquiterpenes and terpenoids content of Valpolicella wines during ageing: investigating aroma potential in relationship to evolution of tobacco and balsamic aroma in aged wine

    NASA Astrophysics Data System (ADS)

    Slaghenaufi, Davide; Ugliano, Maurizio

    2018-03-01

    During wine ageing, tobacco and balsamic aroma notes appear. In this paper, volatile compounds directly or potentially related to those aromas have been investigated in Corvina and Corvinone wines during aging. Corvina and Corvinone are two northern-Italy autochthonous red grape varieties, used to produce Valpolicella Classico and Amarone wines, both characterized by tobacco and balsamic aroma notes. Wines were analysed shortly after bottling or following model ageing at 60 °C for 48, 72, and 168 hours. Volatile compounds were analysed by HS-SPME-GC-MS. Results showed that compounds related to tobacco aroma (β-damascenone, 3-oxo-α-ionol, (E)-1-(2,3,6-Trimethylphenyl)-buta-1,3-diene (TPB) and megastigmatrienones) increased in relationship to storage time with different patterns. β-Damascenone and 3-oxo-α-ionol rapidly increased to reach a plateau in the first 48-72 hours of model ageing. Instead, TPB and megastigmatrienones concentration showed a linear correlation with ageing time. During model ageing, several cyclic terpenes tended to increase. Among them 1,8-cineole and 1,4-cineole, previously reported to contribute to red wine eucalyptus notes increased proportionally to storage time, and this behavior was clearly associated with reactions involving α-terpineol, limonene and terpinolene, as confirmed by studies with model wine solutions. Among other relevant volatile compounds, sesquiterpenes appear to contribute potentially balsamic and spicy aroma notes. In this study, linear sesquiterpenes (nerolidol, farnesol) underwent acid hydrolysis during long wine ageing, while cyclic sesquiterpenes seemed to increase with time. The chemical pathways associated with evolution of some of the compounds investigated have been studied in model wine.

  20. The Diesel Exhaust in Miners Study: III. Interrelations between respirable elemental carbon and gaseous and particulate components of diesel exhaust derived from area sampling in underground non-metal mining facilities.

    PubMed

    Vermeulen, Roel; Coble, Joseph B; Yereb, Daniel; Lubin, Jay H; Blair, Aaron; Portengen, Lützen; Stewart, Patricia A; Attfield, Michael; Silverman, Debra T

    2010-10-01

    Diesel exhaust (DE) has been implicated as a potential lung carcinogen. However, the exact components of DE that might be involved have not been clearly identified. In the past, nitrogen oxides (NO(x)) and carbon oxides (CO(x)) were measured most frequently to estimate DE, but since the 1990s, the most commonly accepted surrogate for DE has been elemental carbon (EC). We developed quantitative estimates of historical exposure levels of respirable elemental carbon (REC) for an epidemiologic study of mortality, particularly lung cancer, among diesel-exposed miners by back-extrapolating 1998-2001 REC exposure levels using historical measurements of carbon monoxide (CO). The choice of CO was based on the availability of historical measurement data. Here, we evaluated the relationship of REC with CO and other current and historical components of DE from side-by-side area measurements taken in underground operations of seven non-metal mining facilities. The Pearson correlation coefficient of the natural log-transformed (Ln)REC measurements with the Ln(CO) measurements was 0.4. The correlation of REC with the other gaseous, organic carbon (OC), and particulate measurements ranged from 0.3 to 0.8. Factor analyses indicated that the gaseous components, including CO, together with REC, loaded most strongly on a presumed 'Diesel exhaust' factor, while the OC and particulate agents loaded predominantly on other factors. In addition, the relationship between Ln(REC) and Ln(CO) was approximately linear over a wide range of REC concentrations. The fact that CO correlated with REC, loaded on the same factor, and increased linearly in log-log space supported the use of CO in estimating historical exposure levels to DE.

  1. The Diesel Exhaust in Miners Study: III. Interrelations between Respirable Elemental Carbon and Gaseous and Particulate Components of Diesel Exhaust derived from Area Sampling in Underground Non-metal Mining Facilities

    PubMed Central

    Vermeulen, Roel; Coble, Joseph B.; Yereb, Daniel; Lubin, Jay H.; Blair, Aaron; Portengen, Lützen; Stewart, Patricia A.; Attfield, Michael; Silverman, Debra T.

    2010-01-01

    Diesel exhaust (DE) has been implicated as a potential lung carcinogen. However, the exact components of DE that might be involved have not been clearly identified. In the past, nitrogen oxides (NOx) and carbon oxides (COx) were measured most frequently to estimate DE, but since the 1990s, the most commonly accepted surrogate for DE has been elemental carbon (EC). We developed quantitative estimates of historical exposure levels of respirable elemental carbon (REC) for an epidemiologic study of mortality, particularly lung cancer, among diesel-exposed miners by back-extrapolating 1998–2001 REC exposure levels using historical measurements of carbon monoxide (CO). The choice of CO was based on the availability of historical measurement data. Here, we evaluated the relationship of REC with CO and other current and historical components of DE from side-by-side area measurements taken in underground operations of seven non-metal mining facilities. The Pearson correlation coefficient of the natural log-transformed (Ln)REC measurements with the Ln(CO) measurements was 0.4. The correlation of REC with the other gaseous, organic carbon (OC), and particulate measurements ranged from 0.3 to 0.8. Factor analyses indicated that the gaseous components, including CO, together with REC, loaded most strongly on a presumed ‘Diesel exhaust’ factor, while the OC and particulate agents loaded predominantly on other factors. In addition, the relationship between Ln(REC) and Ln(CO) was approximately linear over a wide range of REC concentrations. The fact that CO correlated with REC, loaded on the same factor, and increased linearly in log–log space supported the use of CO in estimating historical exposure levels to DE. PMID:20876234

  2. A new large initial condition ensemble to assess avoided impacts in a climate mitigation scenario

    NASA Astrophysics Data System (ADS)

    Sanderson, B. M.; Tebaldi, C.; Knutti, R.; Oleson, K. W.

    2014-12-01

    It has recently been demonstrated that when considering timescales of up to 50 years, natural variability may play an equal role to anthropogenic forcing on subcontinental trends for a variety of climate indicators. Thus, for many questions assessing climate impacts on such time and spatial scales, it has become clear that a significant number of ensemble members may be required to produce robust statistics (and especially so for extreme events). However, large ensemble experiments to date have considered the role of variability in a single scenario, leaving uncertain the relationship between the forced climate trajectory and the variability about that path. To address this issue, we present a new, publicly available, 15 member initial condition ensemble of 21st century climate projections for the RCP 4.5 scenario using the CESM1.1 Earth System Model, which we propose as a companion project to the existing 40 member CESM large ensemble which uses the higher greenhouse gas emission future of RCP8.5. This provides a valuable data set for assessing what societal and ecological impacts might be avoided through a moderate mitigation strategy in contrast to a fossil fuel intensive future. We present some early analyses of these combined ensembles to assess to what degree the climate variability can be considered to combine linearly with the underlying forced response. In regions where there is no detectable relationship between the mean state and the variability about the mean trajectory, then linear assumptions can be trivially exploited to utilize a single ensemble or control simulation to characterize the variability in any scenario of interest. We highlight regions where there is a detectable nonlinearity in extreme event frequency, how far in the future they will be manifested and propose mechanisms to account for these effects.

  3. Scale-dependent segregation of seeders and resprouters in cork oak (Quercus suber) forests.

    PubMed

    Coca, M; Pausas, J G

    2012-02-01

    Recent studies showed that disturbances and water availability determine the richness among plants with different post-fire strategies of Mediterranean-type ecosystems. The aim of this study was to determine whether or not the scale of analysis has an influence on the effects of these factors and, therefore, on the segregation of the dominant post-fire strategies, obligate seeders and obligate resprouters, and facultative species. We recorded all woody species and geographical features on 94 (75 m(2)) plots of cork oak woodlands in the southern Iberian Peninsula. For each regenerative type (resprouters, seeders and species with both traits--facultative species), we tested the relationship between the number of species and the predictors using a generalised linear mixed model. The fixed predictor considered at the large scale was altitude, and fixed predictors considered at the local scale were aspect (north/south) and disturbance (fire and clearing by heavy machinery; yes/no). The random predictor was the factor of site. When this factor did not have significant effect for some regenerative types, these relationships was tested using a generalised linear model. Resprouting species were most represented at lower altitudes and in undisturbed sites, while seeders were also at lower altitudes but mostly on south-facing slopes, especially south-facing disturbed sites. For facultative species, site is the most important variable. The proportion of seeders from the total species is not related to altitude, but it is related to disturbance and aspect. These results suggest that there is no segregation of the richness of seeders and resprouters at the large scale (altitudinal gradient). Differences appeared at the local scale (aspect and disturbance).

  4. Boundary violations and departments of psychiatry.

    PubMed

    Garfinkel, P E; Dorian, B; Sadavoy, J; Bagby, R M

    1997-09-01

    To explore a number of issues related to boundary violations in psychiatry, including the relationship between the individual physician and his or her patient and broader issues related to various dilemmas arising in academic departments of psychiatry. Several potentially troublesome scenarios are presented and discussed in the contexts of 1) the doctor-patient relationship, 2) sexual boundary violations, and 3) nonsexual forms of exploitation, such as finances, confidentiality, dual relationships, and relationships with industry. A number of examples of boundary problems involving psychiatrists have been explored, and although some of these behaviours are clearly forbidden and harmful, others are less clear and require careful consideration if the profession is to arrive at a thoughtful consensus.

  5. USE OF LINEAR FREE ENERGY RELATIONSHIPS AND AN EVALUATIVE MODEL TO ASSESS THE FATE AND TRANSPORT OF PHTHALATE ESTERS IN THE AQUATIC ENVIRONMENT

    EPA Science Inventory

    Linear free energy relationships for selected phthalate esters were used to estimate the rate constants for hydrolysis, biolysis, sediment-water partition coefficients, and biosorption required for modeling. The fate and transport behavior of dimethyl, diethyl, di-n-butyl, di-n-o...

  6. The Effects of Multiple Linked Representations on Students' Learning of Linear Relationships

    ERIC Educational Resources Information Center

    Ozgun-Koca, S. Asli

    2004-01-01

    The focus of this study was on comparing three groups of Algebra I 9th-year students: one group using linked representation software, the second group using similar software but with semi-linked representations, and the control group in order to examine the effects on students' understanding of linear relationships. Data collection methods…

  7. Relationships among Instructional Practices, Students' Motivational Beliefs and Science Achievement in Taiwan Using Hierarchical Linear Modelling

    ERIC Educational Resources Information Center

    Liou, Pey-Yan; Ho, Hsin-Ning Jessie

    2018-01-01

    The purpose of this study is to examine students' perceptions of instructional practices in the classroom, and to further investigate the relationships among instructional practices, motivational beliefs and science achievement. Hierarchical linear modelling was utilised to examine the Trends in International Mathematics and Science Study 2007…

  8. The relationship between compressive strength and flexural strength of pavement geopolymer grouting material

    NASA Astrophysics Data System (ADS)

    Zhang, L.; Han, X. X.; Ge, J.; Wang, C. H.

    2018-01-01

    To determine the relationship between compressive strength and flexural strength of pavement geopolymer grouting material, 20 groups of geopolymer grouting materials were prepared, the compressive strength and flexural strength were determined by mechanical properties test. On the basis of excluding the abnormal values through boxplot, the results show that, the compressive strength test results were normal, but there were two mild outliers in 7days flexural strength test. The compressive strength and flexural strength were linearly fitted by SPSS, six regression models were obtained by linear fitting of compressive strength and flexural strength. The linear relationship between compressive strength and flexural strength can be better expressed by the cubic curve model, and the correlation coefficient was 0.842.

  9. Optimal Loading for Maximizing Power During Sled-Resisted Sprinting.

    PubMed

    Cross, Matt R; Brughelli, Matt; Samozino, Pierre; Brown, Scott R; Morin, Jean-Benoit

    2017-09-01

    To ascertain whether force-velocity-power relationships could be compiled from a battery of sled-resisted overground sprints and to clarify and compare the optimal loading conditions for maximizing power production for different athlete cohorts. Recreational mixed-sport athletes (n = 12) and sprinters (n = 15) performed multiple trials of maximal sprints unloaded and towing a selection of sled masses (20-120% body mass [BM]). Velocity data were collected by sports radar, and kinetics at peak velocity were quantified using friction coefficients and aerodynamic drag. Individual force-velocity and power-velocity relationships were generated using linear and quadratic relationships, respectively. Mechanical and optimal loading variables were subsequently calculated and test-retest reliability assessed. Individual force-velocity and power-velocity relationships were accurately fitted with regression models (R 2 > .977, P < .001) and were reliable (ES = 0.05-0.50, ICC = .73-.97, CV = 1.0-5.4%). The normal loading that maximized peak power was 78% ± 6% and 82% ± 8% of BM, representing a resistance of 3.37 and 3.62 N/kg at 4.19 ± 0.19 and 4.90 ± 0.18 m/s (recreational athletes and sprinters, respectively). Optimal force and normal load did not clearly differentiate between cohorts, although sprinters developed greater maximal power (17.2-26.5%, ES = 0.97-2.13, P < .02) at much greater velocities (16.9%, ES = 3.73, P < .001). Mechanical relationships can be accurately profiled using common sled-training equipment. Notably, the optimal loading conditions determined in this study (69-96% of BM, dependent on friction conditions) represent much greater resistance than current guidelines (~7-20% of BM). This method has potential value in quantifying individualized training parameters for optimized development of horizontal power.

  10. The risk equivalent of an exposure to-, versus a dose of radiation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bond, V.P.

    The long-term potential carcinogenic effects of low-level exposure (LLE) are addressed. The principal point discussed is linear, no-threshold dose-response curve. That the linear no-threshold, or proportional relationship is widely used is seen in the way in which the values for cancer risk coefficients are expressed - in terms of new cases, per million persons exposed, per year, per unit exposure or dose. This implies that the underlying relationship is proportional, i.e., ''linear, without threshold''. 12 refs., 9 figs., 1 tab.

  11. Breastfeeding and Postpartum Depression: An Overview and Methodological Recommendations for Future Research

    PubMed Central

    Pope, Carley J.; Mazmanian, Dwight

    2016-01-01

    Emerging research suggests that a relationship exists between breastfeeding and postpartum depression; however, the direction and precise nature of this relationship are not yet clear. The purpose of this paper is to provide an overview of the relationship between breastfeeding and postpartum depression as it has been examined in the empirical literature. Also, the potential mechanisms of action that have been implicated in this relationship are also explored. PubMed and PsycINFO were searched using the keywords: breastfeeding with postpartum depression, perinatal depression, postnatal depression. Results of this search showed that researchers have examined this relationship in diverse ways using diverse methodology. In particular, researchers have examined the relationships between postpartum depression and breastfeeding intention, initiation, duration, and dose. Due to a number of methodological differences among past studies we make some recommendations for future research that will better facilitate an integration of findings. Future research should (1) use standardized assessment protocols; (2) confirm diagnosis through established clinical interview when possible; (3) provide a clear operationalized definition for breastfeeding variables; (4) clearly define the postpartum period interval assessed and time frame for onset of symptoms; (5) be prospective or longitudinal in nature; and (6) take into consideration other potential risk factors identified in the empirical literature. PMID:27148457

  12. Is the core top modern? Observations from the eastern equatorial Pacific

    NASA Astrophysics Data System (ADS)

    Mekik, Figen; Anderson, Robert

    2018-04-01

    A compilation of ages from 67 core tops in the eastern equatorial Pacific (EEP) does not display an easily discernible regional pattern. The ages range from 790 to over 15,000 years. The youngest core tops with the highest sediment focusing factors are located in the Panama Basin. There are weak but statistically significant inverse relationships between core top age and age-model based mass accumulation rates, bioturbation depth, linear sedimentation rate and sediment focusing factors. However, we found no statistically significant relationship between core top age and calcite dissolution in sediments or 230Th-normalized mass accumulation rates. We found evidence suggesting that greater amount of sediment focusing helps to preserve the carbonate fraction of the sediment where focusing is taking place. When focusing factors are plotted against percent calcite dissolved, we observe a strong inverse relationship, and core tops younger than 4500 years tend to occur where focusing factors are high and percent calcite dissolved values are low. Using labile organic carbon fluxes to estimate bioturbation depth in the sediments results in the observation that where bioturbation depth is shallow (<4 cm), the core top age has a strong, inverse relationship with sediment accumulation rate. We used the Globorotalia menardii Fragmentation Index (MFI) as an indicator of percent calcite dissolved in deep sea sediments. There is a distinct pattern to core top calcite dissolution in the EEP which delineates bands of high surface ocean productivity as well as the clear increase in dissolution downward on the flanks of the East Pacific Rise.

  13. Nonlinear Inverted-U Shaped Relationship between Aging and Epidermal Innervation in the Rat Plantar Hind Paw: a Laser Scanning Confocal Microscopy Study.

    PubMed

    Kaliappan, Sankaranarayanan; Simone, Donald A; Banik, Ratan K

    2018-04-13

    The under-reporting of pain and atypical manifestations of painful syndromes within the elderly population have been well-documented, however, the specific relationship between pain and aging remains ambiguous. Previous studies have reported degenerative changes in primary afferents with aging. In this study, we questioned whether there is any change in the density of primary afferent endings within the epidermis of aged animals. Rats were categorically assessed in four age groups, each representing a key developmental stage across their life span: juvenile (2 months); adult (7 months); aged (18 months); and senescent (24-26 months). The plantar hind paw skin was removed, post-fixed, cut, and immunostained for protein gene product 9.5 and type IV collagen. Rats in the adult aged groups had significantly increased epidermal nerve densities and total lengths of immunoreactive nerve fibers, compared to both juvenile and senescent rats. However, the paw withdrawal thresholds to punctate mechanical stimulation progressively increased with age, and did not exhibit a clear relationship with epidermal innervation. We conclude a non-linear, inverted-U shaped relationship between rat plantar epidermal nerve density with aging, which does not correlate with mechanically-induced paw withdrawal behaviors. This article presents age-related decreased epidermal innervation in rat hind paw skin, which partly explains mechanisms underlying decreased pain sensitivity in aged subjects. The article may help clinicians to understand that any compromise of pain-sensing pathway can lead to under-reporting of pain, inadequate analgesia, and slower recovery from a painful condition. Copyright © 2018. Published by Elsevier Inc.

  14. Relationship between category size and journals' impact factor: implications for emergency medicine journals and researchers.

    PubMed

    Miró, Òscar; Brown, Anthony F T; Graham, Colin A; Ducharme, James; Martin-Sanchez, Francisco J; Cone, David C

    2015-10-01

    We assessed the relationship between the size of the 39 Journal Citation Reports (JCR) medical categories and impact factor (IF) of journals in these categories, and the implications that it might have for emergency medicine (EM) journals. Using the 2010 JCR database, we calculated the mean IF, 5-year IF (5y-IF), Eigenfactor (EF), and Article Influence (AI) scores including all journals for each category. We also calculated a 'weighted IF' for all journals by dividing each journal IF by the mean IF of its category. We ranked EM journals according to IF and 'weighted IF' into all the journals included in the 39 categories. We assessed the relationship between category size and bibliometric scores by linear regression. Category size varied from 252 journals (Pharmacology and Pharmacy) to 14 (Primary Healthcare), EM category occupying the 36th position (23 journals). The mean IF of EM category ranked in 34th position, 5-yIF in 32nd, EF in 34th, and AI in 34th position. Category size had a direct and significant association with mean IF, 5y-IF, and AI but not with mean EF. When the EM journals were ranked among all the journals according to their IF, only two (9%) were placed into the first quartile and raised up to eight (35%) when 'weighted IF' was considered. There is a negative relationship between JCR size category and IF achieved by the journals. This places EM journals at a clear disadvantage because they represent one of the smallest clinical medical research disciplines.

  15. Consumer information needs in a competitive health care environment

    PubMed Central

    Varner, Theresa; Christy, Jack

    1986-01-01

    The role of information in facilitating choice in a competitive health care marketplace is clearly pivotal, but it is also complex and occasionally problematic. Although it is clear that information is critical to the competitive approach, less clear is the relationship between the availability of appropriate information and the exercise of informed choice, a relationship that is obscured in the tangle of influences that affect the use and delivery of medical care. Nonetheless, the centralized and standardized collection, review, and dissemination of relevant health care data remain the keys to predicting—and avoiding—adverse outcomes in the development of health care policy. PMID:10311937

  16. Under which climate and soil conditions the plant productivity-precipitation relationship is linear or nonlinear?

    PubMed

    Ye, Jian-Sheng; Pei, Jiu-Ying; Fang, Chao

    2018-03-01

    Understanding under which climate and soil conditions the plant productivity-precipitation relationship is linear or nonlinear is useful for accurately predicting the response of ecosystem function to global environmental change. Using long-term (2000-2016) net primary productivity (NPP)-precipitation datasets derived from satellite observations, we identify >5600pixels in the North Hemisphere landmass that fit either linear or nonlinear temporal NPP-precipitation relationships. Differences in climate (precipitation, radiation, ratio of actual to potential evapotranspiration, temperature) and soil factors (nitrogen, phosphorous, organic carbon, field capacity) between the linear and nonlinear types are evaluated. Our analysis shows that both linear and nonlinear types exhibit similar interannual precipitation variabilities and occurrences of extreme precipitation. Permutational multivariate analysis of variance suggests that linear and nonlinear types differ significantly regarding to radiation, ratio of actual to potential evapotranspiration, and soil factors. The nonlinear type possesses lower radiation and/or less soil nutrients than the linear type, thereby suggesting that nonlinear type features higher degree of limitation from resources other than precipitation. This study suggests several factors limiting the responses of plant productivity to changes in precipitation, thus causing nonlinear NPP-precipitation pattern. Precipitation manipulation and modeling experiments should combine with changes in other climate and soil factors to better predict the response of plant productivity under future climate. Copyright © 2017 Elsevier B.V. All rights reserved.

  17. Reliability of the Load-Velocity Relationship Obtained Through Linear and Polynomial Regression Models to Predict the One-Repetition Maximum Load.

    PubMed

    Pestaña-Melero, Francisco Luis; Haff, G Gregory; Rojas, Francisco Javier; Pérez-Castilla, Alejandro; García-Ramos, Amador

    2017-12-18

    This study aimed to compare the between-session reliability of the load-velocity relationship between (1) linear vs. polynomial regression models, (2) concentric-only vs. eccentric-concentric bench press variants, as well as (3) the within-participants vs. the between-participants variability of the velocity attained at each percentage of the one-repetition maximum (%1RM). The load-velocity relationship of 30 men (age: 21.2±3.8 y; height: 1.78±0.07 m, body mass: 72.3±7.3 kg; bench press 1RM: 78.8±13.2 kg) were evaluated by means of linear and polynomial regression models in the concentric-only and eccentric-concentric bench press variants in a Smith Machine. Two sessions were performed with each bench press variant. The main findings were: (1) first-order-polynomials (CV: 4.39%-4.70%) provided the load-velocity relationship with higher reliability than second-order-polynomials (CV: 4.68%-5.04%); (2) the reliability of the load-velocity relationship did not differ between the concentric-only and eccentric-concentric bench press variants; (3) the within-participants variability of the velocity attained at each %1RM was markedly lower than the between-participants variability. Taken together, these results highlight that, regardless of the bench press variant considered, the individual determination of the load-velocity relationship by a linear regression model could be recommended to monitor and prescribe the relative load in the Smith machine bench press exercise.

  18. State-variable analysis of non-linear circuits with a desk computer

    NASA Technical Reports Server (NTRS)

    Cohen, E.

    1981-01-01

    State variable analysis was used to analyze the transient performance of non-linear circuits on a desk top computer. The non-linearities considered were not restricted to any circuit element. All that is required for analysis is the relationship defining each non-linearity be known in terms of points on a curve.

  19. Using nonlinear quantile regression to estimate the self-thinning boundary curve

    Treesearch

    Quang V. Cao; Thomas J. Dean

    2015-01-01

    The relationship between tree size (quadratic mean diameter) and tree density (number of trees per unit area) has been a topic of research and discussion for many decades. Starting with Reineke in 1933, the maximum size-density relationship, on a log-log scale, has been assumed to be linear. Several techniques, including linear quantile regression, have been employed...

  20. Comparing Linear Relationships between E-Book Usage and University Student and Faculty Populations: The Differences between E-Reference and E-Monograph Collections

    ERIC Educational Resources Information Center

    Lamothe, Alain R.

    2013-01-01

    This paper reports the results from a quantitative study examining the strength of linear relationships between Laurentian University students and faculty members and the J. N. Desmarais Library's reference and monograph e-book collections. The number of full-text items accessed, searches performed, and undergraduate, graduate, and faculty…

  1. The Trail Less Traveled: Individual Decision-Making and Its Effect on Group Behavior

    PubMed Central

    Lanan, Michele C.; Dornhaus, Anna; Jones, Emily I.; Waser, Andrew; Bronstein, Judith L.

    2012-01-01

    Social insect colonies are complex systems in which the interactions of many individuals lead to colony-level collective behaviors such as foraging. However, the emergent properties of collective behaviors may not necessarily be adaptive. Here, we examine symmetry breaking, an emergent pattern exhibited by some social insects that can lead colonies to focus their foraging effort on only one of several available food patches. Symmetry breaking has been reported to occur in several ant species. However, it is not clear whether it arises as an unavoidable epiphenomenon of pheromone recruitment, or whether it is an adaptive behavior that can be controlled through modification of the individual behavior of workers. In this paper, we used a simulation model to test how symmetry breaking is affected by the degree of non-linearity of recruitment, the specific mechanism used by individuals to choose between patches, patch size, and forager number. The model shows that foraging intensity on different trails becomes increasingly asymmetric as the recruitment response of individuals varies from linear to highly non-linear, supporting the predictions of previous work. Surprisingly, we also found that the direction of the relationship between forager number (i.e., colony size) and asymmetry varied depending on the specific details of the decision rule used by individuals. Limiting the size of the resource produced a damping effect on asymmetry, but only at high forager numbers. Variation in the rule used by individual ants to choose trails is a likely mechanism that could cause variation among the foraging behaviors of species, and is a behavior upon which selection could act. PMID:23112880

  2. The symmetry energy {\\boldsymbol{\\gamma }} parameter of relativistic mean-field models

    NASA Astrophysics Data System (ADS)

    Dutra, Mariana; Lourenço, Odilon; Hen, Or; Piasetzky, Eliezer; Menezes, Débora P.

    2018-05-01

    The relativistic mean-field models tested in previous works against nuclear matter experimental values, critical parameters and macroscopic stellar properties are revisited and used in the evaluation of the symmetry energy γ parameter obtained in three different ways. We have checked that, independent of the choice made to calculate the γ values, a trend of linear correlation is observed between γ and the symmetry energy ({{\\mathscr{S}}}0) and a more clear linear relationship is established between γ and the slope of the symmetry energy (L 0). These results directly contribute to the arising of other linear correlations between γ and the neutron star radii of {R}1.0 and {R}1.4, in agreement with recent findings. Finally, we have found that short-range correlations induce two specific parametrizations, namely, IU-FSU and DD-MEδ, simultaneously compatible with the neutron star mass constraint of 1.93≤slant {M}{{\\max }}/{M}ȯ ≤slant 2.05 and with the overlap band for the {L}0× {{\\mathscr{S}}}0 region, to present γ in the range of γ =0.25+/- 0.05. This work is a part of the project INCT-FNA Proc. No. 464898/2014-5 and was partially supported by Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq), Brazil under grants 300602/2009-0 and 306786/2014-1. E. P. acknowledges support from the Israel Science Foundation. O. H. acknowledges the U.S. Department of Energy Office of Science, Office of Nuclear Physics program under award number DE-FG02-94ER40818

  3. Tongue-Palate Contact Pressure, Oral Air Pressure, and Acoustics of Clear Speech

    ERIC Educational Resources Information Center

    Searl, Jeff; Evitts, Paul M.

    2013-01-01

    Purpose: The authors compared articulatory contact pressure (ACP), oral air pressure (Po), and speech acoustics for conversational versus clear speech. They also assessed the relationship of these measures to listener perception. Method: Twelve adults with normal speech produced monosyllables in a phrase using conversational and clear speech.…

  4. On Spectral Invariance of Single Scattering Albedo for Weakly Absorbing Wavelengths

    NASA Technical Reports Server (NTRS)

    Marshak, Alexander; Knyazikhin, Yuri; Chiu, J. Christine; Wiscombe, Warren J.

    2011-01-01

    This note shows that for water droplets at weakly absorbing wavelengths, the ratio omega(sub O lambda(r))/omega(sub O lambda(r(sub O)) of two single scattering albedo spectra, omega(sub O lambda(r) and omega(sub O lambda(r (sub O)), is a linear function of omega(sub O lambda(r). The slope and intercept of the linear function are wavelength independent and sum to unity. This relationship allows for a representation of any single scattering albedo omega(sub O lambda(r) via one known spectrum omega(sub O lambda(r(sub O)). The note provides a simple physical explanation of the discovered relationship. In addition to water droplets, similar linear relationships were found for the single scattering albedo of non-spherical ice crystals.

  5. Relationships between otolith size and fish length in some mesopelagic teleosts (Myctophidae, Paralepididae, Phosichthyidae and Stomiidae).

    PubMed

    Battaglia, P; Malara, D; Ammendolia, G; Romeo, T; Andaloro, F

    2015-09-01

    Length-mass relationships and linear regressions are given for otolith size (length and height) and standard length (LS ) of certain mesopelagic fishes (Myctophidae, Paralepididae, Phosichthyidae and Stomiidae) living in the central Mediterranean Sea. The length-mass relationship showed isometric growth in six species, whereas linear regressions of LS and otolith size fit the data well for all species. These equations represent a useful tool for dietary studies on Mediterranean marine predators. © 2015 The Fisheries Society of the British Isles.

  6. Aerosol radiative effects and their trends under clear-sky situations over Europe

    NASA Astrophysics Data System (ADS)

    Bartok, Blanka

    2017-04-01

    In the literature great uncertainties ca be found regarding radiative effects of aerosols on the energy budget of the atmosphere (IPCC, 2013). In the study the aerosols radiative effects on clear-sky solar radiation are quantified over Europe using empirical and physical modelling approaches. The values of aerosol radiation effect are determined by the MAGIC radiation code. In the first run clear-sky radiation is calculated integrating KINEE/MPI/Aerocom aerosol climatology and ERA-INTERIM water vapour multiannual monthly means. In the next run the clear-sky radiation are also calculated ignoring aerosol data (adjusted to 0) from the algorithm. Both runs were carried out for each months of the year, taking into account the varying astrological factors. The difference between the aerosol-included and aerosol-free clear-sky radiation is equal to the absolute aerosol radiative effect in W/m2. The annual mean of the surface aerosol radiative effects in clear-sky situations over Europe is -7.1 ± 2.9 W/m2, high values are representing the central part of the continent and the Mediterranean Basin. Furthermore the trends of the aerosol radiative effects are also determined for the period of 2001-2012. First a linear fitting is elaborated between the aerosol optical depth (AOT) built in the MAGIC code and its aerosol radiative effect calculated by the code. Next, based on these linear functions a radiative effect values are assigned to each monthly AOT500 value available from the Moderate Resolution Imaging Spectroradiometer (MODIS) Terra Level-3 experiment. In this way a new dataset of aerosol radiative effect for the period of 2001-2012 has been created. Beside of this approach the changes in aerosol radiative effects are also calculated based on ground-based clear-sky radiation trends. This approach is used as a validation of the method applied in earlier stage, mainly for the linear fitting. The starting point of this approach is to elaborate the trends of clear-sky radiation controlled by the effects of aerosols and water vapour. If we subtract the water vapour effects also calculated by MAGIC radiation code from this trend, the magnitude of the trends in aerosol radiative effects can be estimated. In this case it is assumed that the two effects do not amplify and do not cancel each other, and their arithmetic sum gives the change in clear-sky radiation trend. The two approaches give good fit, based on the direct (modelled) approach the annual trend of the aerosol radiative effects on clear-sky solar surface radiation is -4.41 W/m2 per decade for the period of 2001-2013, while in the case of the indirect approach (based on clear-sky trends) this trend is found to be -4.46 W/m2 per decade.

  7. Linearly chirped fiber Bragg grating response to thermal gradient: from bench tests to the real-time assessment during in vivo laser ablations of biological tissue.

    PubMed

    Saccomandi, Paola; Varalda, Ambra; Gassino, Riccardo; Tosi, Daniele; Massaroni, Carlo; Caponero, Michele A; Pop, Raoul; Korganbayev, Sanzhar; Perrone, Guido; Diana, Michele; Vallan, Alberto; Costamagna, Guido; Marescaux, Jacques; Schena, Emiliano

    2017-09-01

    The response of a fiber optic sensor [linearly chirped fiber Bragg grating (LCFBG)] to a linear thermal gradient applied on its sensing length (i.e., 1.5 cm) has been investigated. After these bench tests, we assessed their feasibility for temperature monitoring during thermal tumor treatment. In particular, we performed experiments during ex vivo laser ablation (LA) in pig liver and in vivo thermal ablation in animal models (pigs). We investigated the following: (i) the relationship between the full width at half maximum of the LCFBG spectrum and the temperature difference among the extremities of the LCFBG and (ii) the relationship between the mean spectrum wavelength and the mean temperature acting on the LCFBG sensing area. These relationships showed a linear trend during both bench tests and LA in animal models. Thermal sensitivity was significant although different values were found with regards to bench tests and animal experiments. The linear trend and significant sensitivity allow hypothesizing a future use of this kind of sensor to monitor both temperature gradient and mean temperature within a tissue undergoing thermal treatment. (2017) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE).

  8. Formation of linear dominance relationship in captive jungle crows (Corvus macrorhynchos): implications for individual recognition.

    PubMed

    Izawa, Ei-Ichi; Watanabe, Shigeru

    2008-05-01

    Jungle crows (Corvus macrorhynchos) flexibly change their social forms depending on their age, time of the day, and the season. In the daytime, paired adults behave territorially and unpaired subadults form small flocks of ten birds, whereas at night hundreds of birds roost together. In the breeding season, pairings remain in their nest all day. This fission-fusion raises questions about the underlying social structure and the cognitive capability of jungle crows. In this study, dyadic encounters were used to investigate dominance relationships (linear or non-linear) and the underlying mechanisms in captive jungle crows. Fourteen crows were tested in 455 encounters (i.e., 5 encounters per dyad), and a stable linear dominance relationship emerged. Sex and aggressiveness were determinants as individual characteristics for dominance formation. Males dominated females, and more aggressive individuals dominated less aggressive ones. Aggressive interactions in dyads occurred primarily during the first encounter and drastically declined during subsequent encounters without any signs of a confidence effect. These results suggest that, in captive jungle crow, a linear form of dominance is intrinsically determined by sex and aggressiveness and maintained extrinsically by memories of past outcomes associated with specific individuals, implying individual recognition.

  9. Testing the Dose–Response Specification in Epidemiology: Public Health and Policy Consequences for Lead

    PubMed Central

    Rothenberg, Stephen J.; Rothenberg, Jesse C.

    2005-01-01

    Statistical evaluation of the dose–response function in lead epidemiology is rarely attempted. Economic evaluation of health benefits of lead reduction usually assumes a linear dose–response function, regardless of the outcome measure used. We reanalyzed a previously published study, an international pooled data set combining data from seven prospective lead studies examining contemporaneous blood lead effect on IQ (intelligence quotient) of 7-year-old children (n = 1,333). We constructed alternative linear multiple regression models with linear blood lead terms (linear–linear dose response) and natural-log–transformed blood lead terms (log-linear dose response). We tested the two lead specifications for nonlinearity in the models, compared the two lead specifications for significantly better fit to the data, and examined the effects of possible residual confounding on the functional form of the dose–response relationship. We found that a log-linear lead–IQ relationship was a significantly better fit than was a linear–linear relationship for IQ (p = 0.009), with little evidence of residual confounding of included model variables. We substituted the log-linear lead–IQ effect in a previously published health benefits model and found that the economic savings due to U.S. population lead decrease between 1976 and 1999 (from 17.1 μg/dL to 2.0 μg/dL) was 2.2 times ($319 billion) that calculated using a linear–linear dose–response function ($149 billion). The Centers for Disease Control and Prevention action limit of 10 μg/dL for children fails to protect against most damage and economic cost attributable to lead exposure. PMID:16140626

  10. A new method to approximate load-displacement relationships of spinal motion segments for patient-specific multi-body models of scoliotic spine.

    PubMed

    Jalalian, Athena; Tay, Francis E H; Arastehfar, Soheil; Liu, Gabriel

    2017-06-01

    Load-displacement relationships of spinal motion segments are crucial factors in characterizing the stiffness of scoliotic spine models to mimic the spine responses to loads. Although nonlinear approach to approximation of the relationships can be superior to linear ones, little mention has been made to deriving personalized nonlinear load-displacement relationships in previous studies. A method is developed for nonlinear approximation of load-displacement relationships of spinal motion segments to assist characterizing in vivo the stiffness of spine models. We propose approximation by tangent functions and focus on rotational displacements in lateral direction. The tangent functions are characterized using lateral bending test. A multi-body model was characterized to 18 patients and utilized to simulate four spine positions; right bending, left bending, neutral, and traction. The same was done using linear functions to assess the performance of the proposed tangent function in comparison with the linear function. Root-mean-square error (RMSE) of the displacements estimated by the tangent functions was 44 % smaller than the linear functions. This shows the ability of our tangent function in approximation of the relationships for a range of infinitesimal to large displacements involved in the spine movement to the four positions. In addition, the models based on the tangent functions yielded 67, 55, and 39 % smaller RMSEs of Ferguson angles, locations of vertebrae, and orientations of vertebrae, respectively, implying better estimates of spine responses to loads. Overall, it can be concluded that our method for approximating load-displacement relationships of spinal motion segments can offer good estimates of scoliotic spine stiffness.

  11. Political conservatism, rigidity, and dogmatism in American foreign policy officials: the 1966 Mennis data.

    PubMed

    Kemmelmeier, Markus

    2007-01-01

    Researchers have established a relationship between political orientation and cognitive styles (A. Chirumbolo, 2002; J. T. Jost, J. Glaser, A. W. Kruglanski, & F. Sulloway, 2003a, 2003b; M. Kemmelmeier, 1997). In this article, the author examined whether this finding is true in the political elite, whether the relationship is linear or curvilinear, and whether interest in politics moderates the relationship between political orientation and cognitive styles. He used a 1966 sample of American foreign policy officials (N = 95) to examine the relationship between self-described conservatism and party identification and individual differences in rigidity and dogmatism. Rigidity was related to self-described conservatism, but this relationship was only significant among participants high in political interest, whereas dogmatism was unconditionally related to party identification. All relationships were linear and did not contain a curvilinear component.

  12. Twitch analysis as an approach to motor unit activation during electrical stimulation.

    PubMed

    Heyters, M; Carpentier, A; Duchateau, J; Hainaut, K

    1994-12-01

    The mechanical twitch in response to increasing electrical stimulus intensity, delivered both over the motor point and motor nerve, was recorded in the first dorsal interosseous (FDI) and the adductor pollicis (AP), and only over the motor point in the soleus (Sol), lateral (LG), and medial (MG) gastrocnemius muscles of human subjects. The relationship between intensity of electrical stimulation (ES) and twitch torque showed a positive linear regression in all muscles. In the FDI and AP the relationship was not significantly different when ES was applied at the motor point or over the motor nerve. At small intensities of activation, ES induced larger twitch torques in the MG and LG, which contain a roughly equal proportion of slow and fast motor units (MUs) compared to the Sol, which is composed mainly of slow type fibres. Moreover, the relationship between ES intensity and twitch time-to-peak is best fitted in all muscles by a power curve that shows a greater twitch time-to-peak range in its initial part for muscles containing a larger proportion of fast MUs (LG, MG) than for muscles mainly composed of slow MUs (Sol). In conclusion, these results induced by ES at the motor point and/or over the motor nerve confirm the concept of a reversed sequence of MU activation, as compared to voluntary contractions, and document this viewpoint in muscles of different function and composition. The reversed sequence of MU activation is more clearly evident during motor point ES.

  13. Can we detect a nonlinear response to temperature in European plant phenology?

    NASA Astrophysics Data System (ADS)

    Jochner, Susanne; Sparks, Tim H.; Laube, Julia; Menzel, Annette

    2016-10-01

    Over a large temperature range, the statistical association between spring phenology and temperature is often regarded and treated as a linear function. There are suggestions that a sigmoidal relationship with definite upper and lower limits to leaf unfolding and flowering onset dates might be more realistic. We utilised European plant phenological records provided by the European phenology database PEP725 and gridded monthly mean temperature data for 1951-2012 calculated from the ENSEMBLES data set E-OBS (version 7.0). We analysed 568,456 observations of ten spring flowering or leafing phenophases derived from 3657 stations in 22 European countries in order to detect possible nonlinear responses to temperature. Linear response rates averaged for all stations ranged between -7.7 (flowering of hazel) and -2.7 days °C-1 (leaf unfolding of beech and oak). A lower sensitivity at the cooler end of the temperature range was detected for most phenophases. However, a similar lower sensitivity at the warmer end was not that evident. For only ˜14 % of the station time series (where a comparison between linear and nonlinear model was possible), nonlinear models described the relationship significantly better than linear models. Although in most cases simple linear models might be still sufficient to predict future changes, this linear relationship between phenology and temperature might not be appropriate when incorporating phenological data of very cold (and possibly very warm) environments. For these cases, extrapolations on the basis of linear models would introduce uncertainty in expected ecosystem changes.

  14. The femur-tibia control system in a proscopiid (Caelifera, Orthoptera): a test for assumptions on the functional basis and evolution of twig mimesis in stick insects.

    PubMed

    Wolf, H; Bässler, U; Spiess, R; Kittmann, R

    2001-11-01

    The extremely slow return movements observed in stick insects (phasmids) after imposed changes in posture are termed catalepsy. In the literature, catalepsy is treated as a behavioural component of the twig mimesis observed in walking stick insects. It is produced by the high gain of the velocity-sensitive component of the relevant joint control systems and by the non-linear dependency of its time constant on movement velocity. The high gain, in turn, causes the system to work close to instability, and this may have driven the evolution of gain control mechanisms. Although these statements represent plausible assumptions, based on correlated occurrence, they remain largely hypothetical like many ideas concerning evolutionary tendencies. To test these hypotheses, we studied catalepsy and the relevant properties of the femur-tibia control system in the middle and hind legs of Prosarthria teretrirostris.cf. Prosarthria teretrirostris is a proscopiid closely related to grasshoppers and locusts. With its slender, green-to-brown body and legs, it shows clear morphological twig mimesis, which has evolved independently of the well-known twig mimesis in stick insects. The animals show clear catalepsy. The main properties of femur-tibia joint control are remarkably similar between proscopiids and stick insects (e.g. the marked sensitivity to movement velocity rather than to joint position and the non-linear dependency of the time constants of response decay on movement velocity), but there are also important differences (habituation and activity-related mechanisms of gain control are absent). Together, these results validate the main concepts that have been developed concerning the neural basis and evolution of catalepsy in stick insects and its relationship to twig mimesis, while demonstrating that ideas on the role of habituation and gain control should be refined.

  15. Aberration measurement technique based on an analytical linear model of a through-focus aerial image.

    PubMed

    Yan, Guanyong; Wang, Xiangzhao; Li, Sikun; Yang, Jishuo; Xu, Dongbo; Erdmann, Andreas

    2014-03-10

    We propose an in situ aberration measurement technique based on an analytical linear model of through-focus aerial images. The aberrations are retrieved from aerial images of six isolated space patterns, which have the same width but different orientations. The imaging formulas of the space patterns are investigated and simplified, and then an analytical linear relationship between the aerial image intensity distributions and the Zernike coefficients is established. The linear relationship is composed of linear fitting matrices and rotation matrices, which can be calculated numerically in advance and utilized to retrieve Zernike coefficients. Numerical simulations using the lithography simulators PROLITH and Dr.LiTHO demonstrate that the proposed method can measure wavefront aberrations up to Z(37). Experiments on a real lithography tool confirm that our method can monitor lens aberration offset with an accuracy of 0.7 nm.

  16. Lack of association between systolic blood pressure and blood viscosity in normotensive healthy subjects.

    PubMed

    Irace, Concetta; Carallo, Claudio; Scavelli, Faustina; Loprete, Antonio; Merante, Valentina; Gnasso, Agostino

    2012-01-01

    A direct relationship between blood pressure and viscosity has frequently been reported, although clear data are not available. To better understand the relationship between these two variables, we evaluated blood viscosity and blood pressure in a group of healthy subjects without cardiovascular risk factors. Healthy subjects were selected from participants in a campaign of prevention of cardiovascular disease (n = 103). They underwent blood sampling for measurement of plasma and blood viscosity, haematocrit, blood lipids and glucose. The quantity and distribution of body fat was assessed by body mass index and waist/hip ratio, respectively. Systolic blood pressure (SBP) correlated significantly with age (r = 0.222) and waist/hip ratio (r = 0.374). Diastolic blood pressure (DBP) correlated significantly with waist/hip ratio (r = 0.216), haematocrit (r = 0.333) and blood viscosity (r = 0.258). Multiple linear regression analyses demonstrated that the only variable significantly associated with SBP was age, while haematocrit was the only variable significantly associated with DBP. Blood viscosity was closely related to waist/hip ratio. These findings show that SBP, in healthy subjects, is not influenced by haematocrit and blood viscosity. In contrast, DBP is related to the values of haematocrit. Among classical cardiovascular risk factors, waist/hip ratio is closely related to blood viscosity.

  17. Nonlinear response of the anterior cingulate and prefrontal cortex in schizophrenia as a function of variable attentional control.

    PubMed

    Blasi, Giuseppe; Taurisano, Paolo; Papazacharias, Apostolos; Caforio, Grazia; Romano, Raffaella; Lobianco, Luciana; Fazio, Leonardo; Di Giorgio, Annabella; Latorre, Valeria; Sambataro, Fabio; Popolizio, Teresa; Nardini, Marcello; Mattay, Venkata S; Weinberger, Daniel R; Bertolino, Alessandro

    2010-04-01

    Previous studies have reported abnormal prefrontal and cingulate activity during attentional control processing in schizophrenia. However, it is not clear how variation in attentional control load modulates activity within these brain regions in this brain disorder. The aim of this study in schizophrenia is to investigate the impact of increasing levels of attentional control processing on prefrontal and cingulate activity. Blood oxygen level-dependent (BOLD) responses of 16 outpatients with schizophrenia were compared with those of 21 healthy subjects while performing a task eliciting increasing levels of attentional control during event-related functional magnetic resonance imaging at 3 T. Results showed reduced behavioral performance in patients at greater attentional control levels. Imaging data indicated greater prefrontal activity at intermediate attentional control levels in patients but greater prefrontal and cingulate responses at high attentional control demands in controls. The BOLD activity profile of these regions in controls increased linearly with increasing cognitive loads, whereas in patients, it was nonlinear. Correlation analysis consistently showed differential region and load-specific relationships between brain activity and behavior in the 2 groups. These results indicate that varying attentional control load is associated in schizophrenia with load- and region-specific modification of the relationship between behavior and brain activity, possibly suggesting earlier saturation of cognitive capacity.

  18. Observed Spectral Invariant Behavior of Zenith Radiance in the Transition Zone Between Cloud-Free and Cloudy Regions

    NASA Technical Reports Server (NTRS)

    Marshak, A.; Knyazikhin, Y.; Chiu, C.; Wiscombe, W.

    2010-01-01

    The Atmospheric Radiation Measurement Program's (ARM) new Shortwave Spectrometer (SWS) looks straight up and measures zenith radiance at 418 wavelengths between 350 and 2200 nm. Because of its 1-sec sampling resolution, the SWS provides a unique capability to study the transition zone between cloudy and clear sky areas. A surprising spectral invariant behavior is found between ratios of zenith radiance spectra during the transition from cloudy to cloud-free atmosphere. This behavior suggests that the spectral signature of the transition zone is a linear mixture between the two extremes (definitely cloudy and definitely clear). The weighting function of the linear mixture is found to be a wavelength-independent characteristic of the transition zone. It is shown that the transition zone spectrum is fully determined by this function and zenith radiance spectra of clear and cloudy regions. This new finding may help us to better understand and quantify such physical phenomena as humidification of aerosols in the relatively moist cloud environment and evaporation and activation of cloud droplets.

  19. Exponential increase in postprandial blood-glucose exposure with increasing carbohydrate loads using a linear carbohydrate-to-insulin ratio.

    PubMed

    Marran, K J; Davey, B; Lang, A; Segal, D G

    2013-04-10

    Postprandial glucose excursions contribute significantly to average blood glucose, glycaemic variability and cardiovascular risk. Carbohydrate counting is a method of insulin dosing that balances carbohydrate load to insulin dose using a fixed ratio. Many patients and current insulin pumps calculate insulin delivery for meals based on a linear carbohydrate-to-insulin relationship. It is our hypothesis that a non-linear relationship exists between the amounts of carbohydrate consumed and the insulin required to cover it. To document blood glucose exposure in response to increasing carbohydrate loads on fixed carbohydrate-to-insulin ratios. Five type 1 diabetic subjects receiving insulin pump therapy with good control were recruited. Morning basal rates and carbohydrate- to-insulin ratios were optimised. A Medtronic glucose sensor was used for 5 days to collect data for area-under-the-curve (AUC) analysis, during which standardised meals of increasing carbohydrate loads were consumed. Increasing carbohydrate loads using a fixed carbohydrate-to-insulin ratio resulted in increasing glucose AUC. The relationship was found to be exponential rather than linear. Late postprandial hypoglycaemia followed carbohydrate loads of >60 g and this was often followed by rebound hyperglycaemia that lasted >6 hours. A non-linear relationship exists between carbohydrates consumed and the insulin required to cover them. This has implications for control of postprandial blood sugars, especially when consuming large carbohydrate loads. Further studies are required to look at the optimal ratios, duration and type of insulin boluses required to cover increasing carbohydrate loads.

  20. 75 FR 57318 - Self-Regulatory Organizations; National Securities Clearing Corporation; Notice of Filing of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-20

    ... Representative and Qualified Special Representative relationships, NSCC proposes to create an automated, online... data have been required to complete and remit to NSCC specific agreements for each relationship... relationship. For QSR relationships, members submit Forms 9a and Form 9b along with an additional form that is...

  1. Relationship Between Motor Variability, Accuracy, and Ball Speed in the Tennis Serve

    PubMed Central

    Antúnez, Ruperto Menayo; Hernández, Francisco Javier Moreno; García, Juan Pedro Fuentes; Vaíllo, Raúl Reina; Arroyo, Jesús Sebastián Damas

    2012-01-01

    The main objective of this study was to analyze the motor variability in the performance of the tennis serve and its relationship to performance outcome. Seventeen male tennis players took part in the research, and they performed 20 serves. Linear and non-linear variability during the hand movement was measured by 3D Motion Tracking. Ball speed was recorded with a sports radar gun and the ball bounces were video recorded to calculate accuracy. The results showed a relationship between the amount of variability and its non-linear structure found in performance of movement and the outcome of the serve. The study also found that movement predictability correlates with performance. An increase in the amount of movement variability could affect the tennis serve performance in a negative way by reducing speed and accuracy of the ball. PMID:23486998

  2. Bio-Inspired Sensing and Display of Polarization Imagery

    DTIC Science & Technology

    2005-07-17

    and weighting coefficients in this example. Panel 4D clearly shows a better visibility, feature extraction , and lesser effect from the background...of linear polarization. Panel E represents the segmentation of the degree of linear polarization, and then Panel F shows the extracted segment with...polarization, and Panel F shows the segment extraction with the finger print selected. Panel G illustrates the application of Canny edge detection to

  3. Disturbances of automatic gait control mechanisms in higher level gait disorder.

    PubMed

    Danoudis, Mary; Ganesvaran, Ganga; Iansek, Robert

    2016-07-01

    The underlying mechanisms responsible for the gait changes in frontal gait disorder (FGD), a form of higher level gait disorders, are poorly understood. We investigated the relationship between stride length and cadence (SLCrel) in people with FGD (n=15) in comparison to healthy older adults (n=21) to improve our understanding of the changes to gait in FGD. Gait data was captured using an electronic walkway system as participants walked at five self-selected speed conditions: preferred, very slow, slow, fast and very fast. Linear regression was used to determine the strength of the relationship (R(2)), slope and intercept. In the FGD group 9 participants had a strong SLCrel (linear group) (R(2)>0.8) and 6 a weak relationship (R(2)<0.8) (nonlinear group). The linear FGD group did not differ to healthy control for slope (p>0.05) but did have a lower intercept (p<0.001). The linear FGD group modulated gait speed by adjusting stride length and cadence similar to controls whereas the nonlinear FGD participants adjusted stride length but not cadence similar to controls. The non-linear FGD group had greater disturbance to their gait, poorer postural control and greater fear of falling compared to the linear FGD group. Investigation of the SLCrel resulted in new insights into the underlying mechanisms responsible for the gait changes found in FGD. The findings suggest stride length regulation was disrupted in milder FGD but as the disorder worsened, cadence control also became disordered resulting in a break down in the relationship between stride length and cadence. Copyright © 2016 Elsevier B.V. All rights reserved.

  4. The lead-lag relationships between spot and futures prices of natural gas

    NASA Astrophysics Data System (ADS)

    Zhang, Yahui; Liu, Li

    2018-01-01

    The lead-lag relationships between spot and futures markets are of great interest for academics. Previous studies neglect the possibility of nonlinear behaviors which may be caused by asymmetry or persistence. To fill this gap, this paper uses the MF-DCCA method and the linear and nonlinear causality tests to explore the causal relationships between natural gas spot and futures prices in the New York Mercantile Exchange. We find that spot and futures prices are positive cross-correlated, the natural gas futures can linearly Granger cause spot price, and there are bidirectional nonlinear causality relationships between natural gas spot and futures prices. Further, we explore the sources of nonlinear causality relationships, and find that the volatility spillover can partly explain the nonlinear causality and affect their cross-correlations.

  5. Linear proportional relationship between N(OH) and N(CH) in the diffuse interstellar medium

    NASA Astrophysics Data System (ADS)

    Hong, Seung Yeong; Kwak, Kyujin

    2018-04-01

    It has been known that there is a linearly proportional relationship between the column densities of CH and OH measured toward bright UV-emitting stars, although there are four outliers in this relationship among the total 24 measured targets. By using the Simbad database, we investigate reasonable configurations of diffuse interstellar medium (ISM) which could explain the observed relationship. We first identify the locations of 24 targets on the celestial sphere getting the distances to them and then count the number of molecular clouds, nebulae, and peculiar stars toward the targets which could contribute to the production of OH and CH. We present the results of our search by testing three hypothetical configurations of diffuse ISM which may explain the observed relationship.

  6. Resolution Improvements in in Vivo1H NMR Spectra with Increased Magnetic Field Strength

    NASA Astrophysics Data System (ADS)

    Gruetter, Rolf; Weisdorf, Sally A.; Rajanayagan, Vasantham; Terpstra, Melissa; Merkle, Hellmut; Truwit, Charles L.; Garwood, Michael; Nyberg, Scott L.; Ugurbil, Kâmil

    1998-11-01

    The measurement of cerebral metabolites using highly homologous localization techniques and similar shimming methods was performed in the human brain at 1.5 and 4 T as well as in the dog and rat brain at 9.4 T. In rat brain, improved resolution was achieved by shimming all first- and second-order shim coils using a fully adiabatic FASTMAP sequence. The spectra showed a clear improvement in spectral resolution for all metabolite resonances with increased field strength. Changes in cerebral glutamine content were clearly observed at 4 T compared to 1.5 T in patients with hepatic encephalopathy. At 9.4 T, glutamine H4 at 2.46 ppm was fully resolved from glutamate H4 at 2.37 ppm, as was the potential resonance from γ-amino-butyric acid at 2.30 ppm and N-acetyl-aspartyl-glutamate at 2.05 ppm. Singlet linewidths were found to be as low as 6 Hz (0.015 ppm) at 9.4 T, indicating a substantial decrease in ppm linewidth with field strength. Furthermore, the methylene peak of creatine was partially resolved from phosphocreatine, indicating a close to 1:1 relationship in gray matter. We conclude that increasing the magnetic field strength increases spectral resolution also for1H NMR, which can lead to more than linear sensitivity gains.

  7. Soil respiration and photosynthetic uptake of carbon dioxide by ground-cover plants in four ages of jack pine forest

    USGS Publications Warehouse

    Striegl, Robert G.; Wickland, K.P.

    2001-01-01

    Soil carbon dioxide (CO2) emission (soil respiration), net CO2 exchange after photosynthetic uptake by ground-cover plants, and soil CO2 concentration versus depth below land surface were measured at four ages of jack pine (Pinus banksiana Lamb.) forest in central Saskatchewan. Soil respiration was smallest at a clear-cut site, largest in an 8-year-old stand, and decreased with stand age in 20-year-old and mature (60-75 years old) stands during May-September 1994 (12.1, 34.6, 31.5, and 24.9 mol C??m-2, respectively). Simulations of soil respiration at each stand based on continuously recorded soil temperature were within one standard deviation of measured flux for 48 of 52 measurement periods, but were 10%-30% less than linear interpolations of measured flux for the season. This was probably due to decreased soil respiration at night modeled by the temperature-flux relationships, but not documented by daytime chamber measurements. CO2 uptake by ground-cover plants ranged from 0 at the clear-cut site to 29, 25, and 9% of total growing season soil respiration at the 8-year, 20-year, and mature stands. CO2 concentrations were as great as 7150 ppmv in the upper 1 m of unsaturated zone and were proportional to measured soil respiration.

  8. Displayed Trees Do Not Determine Distinguishability Under the Network Multispecies Coalescent

    PubMed Central

    Zhu, Sha; Degnan, James H.

    2017-01-01

    Abstract Recent work in estimating species relationships from gene trees has included inferring networks assuming that past hybridization has occurred between species. Probabilistic models using the multispecies coalescent can be used in this framework for likelihood-based inference of both network topologies and parameters, including branch lengths and hybridization parameters. A difficulty for such methods is that it is not always clear whether, or to what extent, networks are identifiable—that is whether there could be two distinct networks that lead to the same distribution of gene trees. For cases in which incomplete lineage sorting occurs in addition to hybridization, we demonstrate a new representation of the species network likelihood that expresses the probability distribution of the gene tree topologies as a linear combination of gene tree distributions given a set of species trees. This representation makes it clear that in some cases in which two distinct networks give the same distribution of gene trees when sampling one allele per species, the two networks can be distinguished theoretically when multiple individuals are sampled per species. This result means that network identifiability is not only a function of the trees displayed by the networks but also depends on allele sampling within species. We additionally give an example in which two networks that display exactly the same trees can be distinguished from their gene trees even when there is only one lineage sampled per species. PMID:27780899

  9. Unveiling the molecular bipolar outflow of the peculiar red supergiant VY Canis Majoris

    NASA Astrophysics Data System (ADS)

    Shinnaga, Hiroko; Claussen, Mark J.; Lim, Jeremy; Dinh-van-Trung; Tsuboi, Masato

    2003-04-01

    We carried out polarimetric spectral-line imaging of the molecular outflow of the peculiar red supergiant VY Canis Majoris in SiO J=1-0 line in the ground vibrational state, which contains highly linearly-polarized velocity components, using the Very Large Array. We succeeded in unveiling the highly linearly polarized bipolar outflow for the first time at subarcsecond spatial resolution. The results clearly show that the direction of linear polarization of the brightest maser components is parallel to the outflow axis. The results strongly suggest that the linear polarization of the SiO maser is closely related to the outflow phenomena of the star. Furthermore, the results indicate that the linear polarization observed in the optical and infrared also occur due to the outflow phenomena.

  10. Multiple Intelligence Scores of Science Stream Students and Their Relation with Reading Competency in Malaysian University English Test (MUET)

    ERIC Educational Resources Information Center

    Razak, Norizan Abdul; Zaini, Nuramirah

    2014-01-01

    Many researches have shown that different approach needed in analysing linear and non-linear reading comprehension texts and different cognitive skills are required. This research attempts to discover the relationship between Science Stream students' reading competency on linear and non-linear texts in Malaysian University English Test (MUET) with…

  11. LINEARIZATION OF EMPIRICAL RHEOLOGICAL DATA FOR USE IN COMPOSITION CONTROL OF MULTICOMPONENT FOODSTUFFS.

    PubMed

    Drake, Birger; Nádai, Béla

    1970-03-01

    An empirical measure of viscosity, which is often far from being a linear function of composition, was used together with refractive index to build up a function which bears a linear relationship to the composition of tomato paste-water-sucrose mixtures. The new function can be used directly for rapid composition control by linear vector-vector transformation.

  12. Skin optical clearing potential of disaccharides

    NASA Astrophysics Data System (ADS)

    Feng, Wei; Shi, Rui; Ma, Ning; Tuchina, Daria K.; Tuchin, Valery V.; Zhu, Dan

    2016-08-01

    Skin optical clearing can significantly enhance the ability of biomedical optical imaging. Some alcohols and sugars have been selected to be optical clearing agents (OCAs). In this work, we paid attention to the optical clearing potential of disaccharides. Sucrose and maltose were chosen as typical disaccharides to compare with fructose, an excellent monosaccharide-OCA, by using molecular dynamics simulation and an ex vivo experiment. The experimental results indicated that the optical clearing efficacy of skin increases linearly with the concentration for each OCA. Both the theoretical predication and experimental results revealed that the two disaccharides exerted a better optical clearing potential than fructose at the same concentration, and sucrose is optimal. Since maltose has an extremely low saturation concentration, the other two OCAs with saturation concentrations were treated topically on rat skin in vivo, and optical coherence tomography imaging was applied to monitor the optical clearing process. The results demonstrated that sucrose could cause a more significant increase in imaging depth and signal intensity than fructose.

  13. Clozapine-Related EEG Changes and Seizures: Dose and Plasma-Level Relationships

    PubMed Central

    Varma, Seema; Bishara, Delia; Besag, Frank M. C.; Taylor, David

    2011-01-01

    Clozapine is a widely used atypical antipsychotic with a unique effectiveness in treatment-resistant schizophrenia. An important adverse effect is seizures, which have been observed at all stages of clozapine treatment. Valproate has traditionally been considered the drug of choice for the prophylaxis of clozapine seizures, however it may not be the most suitable choice for all patients. There is disagreement as to the best point to prescribe valproate or a suitable antiepileptic: as seizure prophylaxis at a certain clozapine dose or level, or only as remedial treatment. In this review, we examine the relevant literature with an aim to evaluate the following relationships: clozapine dose and electroencephalogram (EEG) abnormalities, plasma levels and EEG abnormalities, dose and occurrence of seizures and plasma levels and occurrence of seizures. Weighted linear regression models were fitted to investigate these relationships. There was a strong relationship between clozapine dose and plasma level and occurrence of clozapine-induced EEG abnormalities. However, a statistically significant relationship between dose and occurrence of seizures was not found. A relationship between clozapine plasma level and occurrence of seizures was not established because of the scarcity of useful data although our review found three case reports which suggested that there is a very substantial risk of seizures with clozapine plasma levels exceeding 1300 μg/l. Seizures are more common during the initiation phase of clozapine treatment, suggesting a slow titration to target plasma levels is desirable. An antiepileptic drug should be considered when the clozapine plasma level exceeds 500 μg/l, if the EEG shows clear epileptiform discharges, if seizures, myoclonic jerks or speech difficulties occur and when there is concurrent use of epileptogenic medication. The antiepileptics of choice for the treatment and prophylaxis of clozapine-induced seizures are valproate (particularly where there is mood disturbance) and lamotrigine (where there is resistance to clozapine). PMID:23983927

  14. Asian dust deposition rendered volcanic-ash-soils the ability to retain radiocesium in Japan

    NASA Astrophysics Data System (ADS)

    Nakao, A.; Uno, S.; Tanaka, R.; Yanai, J.; Kosaki, T.; Kubotera, H.

    2017-12-01

    Although mineral dusts are known to contribute greatly to marine and terrestrial biogeochemical cycles, their role in increasing the retention of radio-Cs in soil is less clear. Fine-mica, which is one of the main component of Asian dust, has a specific adsorption site for radio-Cs. Therefore, historical deposition of Asian dust may have rendered soils in Japan capable of retaining radio-Cs. This effect may be particularly important for volcanic-ash derived soils since they originally contain only small amounts of fine-mica. To test this hypothesis, we investigated 47 soils in volcanic ash-fall layers at four sites (Site 1, 2, 3, 4) with a different distance from volcanic crater of Mt. Aso, Japan, which is 10, 14, 16, and 32 km, respectively. Soils were collected from surface to the volcanic layer with 7.3 ka in Site 1 and 2, whereas from surface to the layer with 30 ka in Site 3 and 4. Ages of key layers were confirmed by tephrochronology and 14C dating method. Oxygen isotopic ratio (d18O) value of fine-quartz was used as a fingerprint of Asian dust in each volcanic layer. Average d18O value for fine-quartz from Site 3 and 4 was 16.0 ± 0.4‰, which was homogeneous and very close to those of fine-quartz in Gobi Desert, while clearly different from those of SiO2 in volcanic rocks. Fine-quartz and fine-mica contents were larger with increased distance from the volcanic crater and showed a linear relationship. Cumulative amount of fine-mica in the layers deposited during the last glacial period (i.e. 10 ka to 30 ka) was about five times larger than those deposited during the postglacial period (i.e. < 10 ka). These results clearly indicated that fine-mica in the volcanic ash-fall layers are mostly derived from Asian dust. Since radio-Cs adsorption experiment revealed that the ability to retain radio-Cs increased linearly as soils contained larger amount of fine-mica, we concluded that the inclusion rate of Asian dust to volcanic ash determine the ability to retain radio-Cs in volcanic-ash soils in Japan and probably any other soil influenced by these aeolian materials.

  15. [Quantitative relationship between gas chromatographic retention time and structural parameters of alkylphenols].

    PubMed

    Ruan, Xiaofang; Zhang, Ruisheng; Yao, Xiaojun; Liu, Mancang; Fan, Botao

    2007-03-01

    Alkylphenols are a group of permanent pollutants in the environment and could adversely disturb the human endocrine system. It is therefore important to effectively separate and measure the alkylphenols. To guide the chromatographic analysis of these compounds in practice, the development of quantitative relationship between the molecular structure and the retention time of alkylphenols becomes necessary. In this study, topological, constitutional, geometrical, electrostatic and quantum-chemical descriptors of 44 alkylphenols were calculated using a software, CODESSA, and these descriptors were pre-selected using the heuristic method. As a result, three-descriptor linear model (LM) was developed to describe the relationship between the molecular structure and the retention time of alkylphenols. Meanwhile, the non-linear regression model was also developed based on support vector machine (SVM) using the same three descriptors. The correlation coefficient (R(2)) for the LM and SVM was 0.98 and 0. 92, and the corresponding root-mean-square error was 0. 99 and 2. 77, respectively. By comparing the stability and prediction ability of the two models, it was found that the linear model was a better method for describing the quantitative relationship between the retention time of alkylphenols and the molecular structure. The results obtained suggested that the linear model could be applied for the chromatographic analysis of alkylphenols with known molecular structural parameters.

  16. How social opinion influences syntactic processing-An investigation using virtual reality.

    PubMed

    Heyselaar, Evelien; Hagoort, Peter; Segaert, Katrien

    2017-01-01

    The extent to which you adapt your grammatical choices to match that of your interlocutor's (structural priming) can be influenced by the social opinion you have of your interlocutor. However, the direction and reliability of this effect is unclear as different studies have reported seemingly contradictory results. We have operationalized social perception as the ratings of strangeness for different avatars in a virtual reality study. The use of avatars ensured maximal control over the interlocutor's behaviour and a clear dimension along which to manipulate social perceptions toward this interlocutor. Our results suggest an inverted U-shaped curve in structural priming magnitude for passives as a function of strangeness: the participants showed the largest priming effects for the intermediately strange, with a decrease when interacting with the least- or most-strange avatars. The relationship between social perception and priming magnitude may thus be non-linear. There seems to be a 'happy medium' in strangeness, evoking the largest priming effect. We did not find a significant interaction of priming magnitude with any social perception.

  17. Simulating sunflower canopy temperatures to infer root-zone soil water potential

    NASA Technical Reports Server (NTRS)

    Choudhury, B. J.; Idso, S. B.

    1983-01-01

    A soil-plant-atmosphere model for sunflower (Helianthus annuus L.), together with clear sky weather data for several days, is used to study the relationship between canopy temperature and root-zone soil water potential. Considering the empirical dependence of stomatal resistance on insolation, air temperature and leaf water potential, a continuity equation for water flux in the soil-plant-atmosphere system is solved for the leaf water potential. The transpirational flux is calculated using Monteith's combination equation, while the canopy temperature is calculated from the energy balance equation. The simulation shows that, at high soil water potentials, canopy temperature is determined primarily by air and dew point temperatures. These results agree with an empirically derived linear regression equation relating canopy-air temperature differential to air vapor pressure deficit. The model predictions of leaf water potential are also in agreement with observations, indicating that measurements of canopy temperature together with a knowledge of air and dew point temperatures can provide a reliable estimate of the root-zone soil water potential.

  18. Science and policy applicability of the transient climate response to cumulative emissions of carbon

    NASA Astrophysics Data System (ADS)

    Rogelj, J.

    2014-12-01

    The Transient Climate Response to cumulative Carbon Emissions (TCRE) provides a quantification of the near-linear relationship between cumulative emissions of carbon and global-mean temperature increase. For its most recent report, the Intergovernmental Panel on Climate Change bases its assessment on a large body of literature which encompasses multiple lines of evidence. In this session I will look at the literature basis that was available for TCRE at the time of the IPCC Fifth Assessment Report, providing an easy-to-access introduction into the TCRE concept. Building on this basis and summarizing my own recent work on this, I will discuss the strengths and weaknesses of the use of TCRE for climate policy. While the TCRE concept provides a clear long-term view of what is required to stabilize global-mean temperature increase, I will explore how TCRE uncertainties might pose problems for using TCRE as the only policy guidance in near-term policy decisions.

  19. Impact of local traffic exclusion on near-road air quality: findings from the New York City "Summer Streets" campaign.

    PubMed

    Whitlow, Thomas H; Hall, Andrew; Zhang, K Max; Anguita, Juan

    2011-01-01

    We monitored curbside airborne particulate matter (PM) concentrations and its proinflammatory capacity during 3 weekends when vehicle traffic was excluded from Park. Ave., New York City. Fine PM concentration peaked in the morning regardless of traffic while ultrafine PM was 58% lower during mornings without traffic. Ultrafine PM concentration varied linearly with traffic flow, while fine PM spiked sharply in response to random traffic events that were weakly correlated with the traffic signal cycle. Ultrafine PM concentrations decayed exponentially with distance from a cross street with unrestricted traffic flow, reaching background levels within 100 m of the source. IL-6 induction was typically highest on Friday afternoons but showed no clear relationship to the presence of traffic. The coarse fraction (>2.5 μm) had the greatest intrinsic inflammatory capacity, suggesting that coarse PM still warrants attention even as the research focus is shifting to nano-particles. Copyright © 2011 Elsevier Ltd. All rights reserved.

  20. Ultra-Sensitive Strain Sensor Based on Flexible Poly(vinylidene fluoride) Piezoelectric Film

    NASA Astrophysics Data System (ADS)

    Lu, Kai; Huang, Wen; Guo, Junxiong; Gong, Tianxun; Wei, Xiongbang; Lu, Bing-Wei; Liu, Si-Yi; Yu, Bin

    2018-03-01

    A flexible 4 × 4 sensor array with 16 micro-scale capacitive units has been demonstrated based on flexible piezoelectric poly(vinylidene fluoride) (PVDF) film. The piezoelectricity and surface morphology of the PVDF were examined by optical imaging and piezoresponse force microscopy (PFM). The PFM shows phase contrast, indicating clear interface between the PVDF and electrode. The electro-mechanical properties show that the sensor exhibits excellent output response and an ultra-high signal-to-noise ratio. The output voltage and the applied pressure possess linear relationship with a slope of 12 mV/kPa. The hold-and-release output characteristics recover in less than 2.5 μs, demonstrating outstanding electro-mechanical response. Additionally, signal interference between the adjacent arrays has been investigated via theoretical simulation. The results show the interference reduces with decreasing pressure at a rate of 0.028 mV/kPa, highly scalable with electrode size and becoming insignificant for pressure level under 178 kPa.

  1. Length of stay, discharge destination, and functional improvement: utility of the Australian National Subacute and Nonacute Patient Casemix Classification.

    PubMed

    Tooth, Leigh; McKenna, Kryss; Goh, Kong; Varghese, Paul

    2005-07-01

    Although implemented in 1998, no research has examined how well the Australian National Subacute and Nonacute Patient (AN-SNAP) Casemix Classification predicts length of stay (LOS), discharge destination, and functional improvement in public hospital stroke rehabilitation units in Australia. 406 consecutive admissions to 3 stroke rehabilitation units in Queensland, Australia were studied. Sociodemographic, clinical, and functional data were collected. General linear modeling and logistic regression were used to assess the ability of AN-SNAP to predict outcomes. AN-SNAP significantly predicted each outcome. There were clear relationships between the outcomes of longer LOS, poorer functional improvement and discharge into care, and the AN-SNAP classes that reflected poorer functional ability and older age. Other predictors included living situation, acute LOS, comorbidity, and stroke type. AN-SNAP is a consistent predictor of LOS, functional change and discharge destination, and has utility in assisting clinicians to set rehabilitation goals and plan discharge.

  2. Design of capacitive sensor for water level measurement

    NASA Astrophysics Data System (ADS)

    Qurthobi, A.; Iskandar, R. F.; Krisnatal, A.; Weldzikarvina

    2016-11-01

    Capacitive sensor for water level detection has been fabricated. It has, typically, high-impedance sensor, particularly at low frequencies, as clear from the impedance (reactance) expression for a capacitor. Also, capacitive sensor is a noncontacting device in the common usage. In this research, water level sensor based on capacitive principal created using two copper plates with height (h), width (b), and distance (l) between two plates, respectively, 0.040 m, 0.015 m, and 0.010 m. 5 V pp 3 kHz AC signal is used as input signal for the system. Dielectric constant between two plates is proportional to water level. Hence, it can be used to determine water level from electrical characteristic as it inversely proportional to sensor impedance. Linearization, inverting amplifier, and rectifier circuits are used as signal conditioning for the system. Based on conducted experiment, the relationship between water level (x), capacitance (C), and output voltage (Vdc ) can be expressed as C(x) = 2.756x + 0.333 nF and Vdc (x) = 15.755 + 0.316 V.

  3. Ultra-Sensitive Strain Sensor Based on Flexible Poly(vinylidene fluoride) Piezoelectric Film.

    PubMed

    Lu, Kai; Huang, Wen; Guo, Junxiong; Gong, Tianxun; Wei, Xiongbang; Lu, Bing-Wei; Liu, Si-Yi; Yu, Bin

    2018-03-14

    A flexible 4 × 4 sensor array with 16 micro-scale capacitive units has been demonstrated based on flexible piezoelectric poly(vinylidene fluoride) (PVDF) film. The piezoelectricity and surface morphology of the PVDF were examined by optical imaging and piezoresponse force microscopy (PFM). The PFM shows phase contrast, indicating clear interface between the PVDF and electrode. The electro-mechanical properties show that the sensor exhibits excellent output response and an ultra-high signal-to-noise ratio. The output voltage and the applied pressure possess linear relationship with a slope of 12 mV/kPa. The hold-and-release output characteristics recover in less than 2.5 μs, demonstrating outstanding electro-mechanical response. Additionally, signal interference between the adjacent arrays has been investigated via theoretical simulation. The results show the interference reduces with decreasing pressure at a rate of 0.028 mV/kPa, highly scalable with electrode size and becoming insignificant for pressure level under 178 kPa.

  4. Cross-entropy embedding of high-dimensional data using the neural gas model.

    PubMed

    Estévez, Pablo A; Figueroa, Cristián J; Saito, Kazumi

    2005-01-01

    A cross-entropy approach to mapping high-dimensional data into a low-dimensional space embedding is presented. The method allows to project simultaneously the input data and the codebook vectors, obtained with the Neural Gas (NG) quantizer algorithm, into a low-dimensional output space. The aim of this approach is to preserve the relationship defined by the NG neighborhood function for each pair of input and codebook vectors. A cost function based on the cross-entropy between input and output probabilities is minimized by using a Newton-Raphson method. The new approach is compared with Sammon's non-linear mapping (NLM) and the hierarchical approach of combining a vector quantizer such as the self-organizing feature map (SOM) or NG with the NLM recall algorithm. In comparison with these techniques, our method delivers a clear visualization of both data points and codebooks, and it achieves a better mapping quality in terms of the topology preservation measure q(m).

  5. Thermodynamic analysis of sol-gel transition of gelatin in terms of water activity in various solutions.

    PubMed

    Miyawaki, Osato; Omote, Chiaki; Matsuhira, Keiko

    2015-12-01

    Sol-gel transition of gelatin was analyzed as a multisite stoichiometric reaction of a gelatin molecule with water and solute molecules. The equilibrium sol-gel transition temperature, Tt , was estimated from the average of gelation and melting temperature measured by differential scanning calorimetry. From Tt and the melting enthalpy, ΔHsol , the equilibrium sol-to-gel ratio was estimated by the van't Hoff equation. The reciprocal form of the Wyman-Tanford equation, which describes the sol-to-gel ratio as a function of water activity, was successfully applied to obtain a good linear relationship. From this analysis, the role of water activity on the sol-gel transition of gelatin was clearly explained and the contributions of hydration and solute binding to gelatin molecules were separately discussed in sol-gel transition. The general solution for the free energy for gel-stabilization in various solutions was obtained as a simple function of solute concentration. © 2015 Wiley Periodicals, Inc.

  6. Structural investigations in the Massif-Central, France

    NASA Technical Reports Server (NTRS)

    Scanvic, J. Y.

    1974-01-01

    This survey covered the French Massif-Central (where crystalline and volcanic rocks outcrop) and its surrounding sedimentaries, Bassin de Paris, Bassin d'Aquitaine and Rhodanian valley. One objective was the mapping of fracturing and the surveying of its relationship with known ore deposits. During this survey it was found that ERTS imagery outlines lithology in some sedimentary basins. On the other hand, in a basement area, under temperature climate conditions, lithology is rarely expressed. These observations can be related to the fact that band 5 gives excellent results above sedimentary basins in France and generally band 7 is the most useful in a basement area. Several examples show clearly the value of ERTS imagery for mapping linear features and circular structures. All the main fractures are identified with the exception of new ones found both in sedimentaries and basement areas. Other interesting findings concern sun elevation which, stereoscopic effect not being possible, simulates relief in a better way under certain conditions.

  7. A renewed perspective on agroforestry concepts and classification.

    PubMed

    Torquebiau, E F

    2000-11-01

    Agroforestry, the association of trees with farming practices, is progressively becoming a recognized land-use discipline. However, it is still perceived by some scientists, technicians and farmers as a sort of environmental fashion which does not deserve credit. The peculiar history of agroforestry and the complex relationships between agriculture and forestry explain some misunderstandings about the concepts and classification of agroforestry and reveal that, contrarily to common perception, agroforestry is closer to agriculture than to forestry. Based on field experience from several countries, a structural classification of agroforestry into six simple categories is proposed: crops under tree cover, agroforests, agroforestry in a linear arrangement, animal agroforestry, sequential agroforestry and minor agroforestry techniques. It is argued that this pragmatic classification encompasses all major agroforestry associations and allows simultaneous agroforestry to be clearly differentiated from sequential agroforestry, two categories showing contrasting ecological tree-crop interactions. It can also contribute to a betterment of the image of agroforestry and lead to a simplification of its definition.

  8. Home ranges and satellite tactics of male green swordtails (Xiphophorus helleri) in nature.

    PubMed

    Franck, D; Klamroth, B; Taebel-Hellwig, A; Schartl, M

    1998-05-01

    Dominance relationships were studied between marked or otherwise individually recognizable male green swordtails in a creek at Lake Catemaco and in a tributary of the Rio Atoyac (Veracruz, Mexico). The Atoyac population is unique because of a high degree of polymorphism, including both macromelanophore spotting and a micromelanophore tailspot pattern. During the dry season males living in the same area maintained a linear social hierarchy for periods of many days. The subordinate males settled down either in the same home ranges or in home ranges largely overlapping with that of dominant males. Although dominant males untiringly chased the subordinate males away, they returned persistently and achieved the status of non-tolerated satellites. Females were less stationary and presumably passed through many male home ranges during their feeding activities. The data clearly demonstrate that green swordtails live in complex social systems in which male-male competition and probably also female mate choice are likely to be essential factors for individual reproductive success.

  9. Relationships between Loblolly Pine small clear specimens and Dimension Lumber Tested in Static Bending

    Treesearch

    Mark Alexander Butler; Joseph Dahlen; Finto Antony; Michael Kane; Thomas L. Eberhardt; Huizhe Jin; Kim Love-Myers; John Paul McTague

    2016-01-01

    Prior to the 1980s, the allowable stresses for lumber in North America were derived from testing of small clear specimens. However, the procedures were changed because these models were found to be inaccurate. Nevertheless, small clear testing continues to be used around the world for allowable stress determinations and in studies that examine forest management impacts...

  10. The Relationship Between X-Ray Radiance and Magnetic Flux

    NASA Astrophysics Data System (ADS)

    Pevtsov, Alexei A.; Fisher, George H.; Acton, Loren W.; Longcope, Dana W.; Johns-Krull, Christopher M.; Kankelborg, Charles C.; Metcalf, Thomas R.

    2003-12-01

    We use soft X-ray and magnetic field observations of the Sun (quiet Sun, X-ray bright points, active regions, and integrated solar disk) and active stars (dwarf and pre-main-sequence) to study the relationship between total unsigned magnetic flux, Φ, and X-ray spectral radiance, LX. We find that Φ and LX exhibit a very nearly linear relationship over 12 orders of magnitude, albeit with significant levels of scatter. This suggests a universal relationship between magnetic flux and the power dissipated through coronal heating. If the relationship can be assumed linear, it is consistent with an average volumetric heating rate Q~B/L, where B is the average field strength along a closed field line and L is its length between footpoints. The Φ-LX relationship also indicates that X-rays provide a useful proxy for the magnetic flux on stars when magnetic measurements are unavailable.

  11. Curvilinear relationships between resource allocation and life domain-specific interference.

    PubMed

    Waldrop, Jessica S; Erb, Kaitlyn R; Grawitch, Matthew J

    2017-10-01

    This study investigated the inherent complexities of the work-life interface (WLI) by examining the relationship between resource allocation (i.e., time and energy dedicated to a particular domain) and perceived interference of individual life domains. Much of the research on the WLI is based on the assumption that a linear pattern best describes the relationship between resource allocation and the interference caused by various life domains; however, this study examined the possibility that curvilinear relationships may be a more appropriate representation. Results indicated that resource allocation is a meaningful predictor of interference, and for many life domains a curvilinear relationship accounts for more variance than a linear one; a breakdown of the sample also revealed this relationship varies by gender. Overall, findings suggest that the nature of the WLI is more individualized and complex than is currently conceptualized in the field. Copyright © 2016 John Wiley & Sons, Ltd.

  12. Diagnosis of Enzyme Inhibition Using Excel Solver: A Combined Dry and Wet Laboratory Exercise

    ERIC Educational Resources Information Center

    Dias, Albino A.; Pinto, Paula A.; Fraga, Irene; Bezerra, Rui M. F.

    2014-01-01

    In enzyme kinetic studies, linear transformations of the Michaelis-Menten equation, such as the Lineweaver-Burk double-reciprocal transformation, present some constraints. The linear transformation distorts the experimental error and the relationship between "x" and "y" axes; consequently, linear regression of transformed data…

  13. Deriving Hounsfield units using grey levels in cone beam computed tomography

    PubMed Central

    Mah, P; Reeves, T E; McDavid, W D

    2010-01-01

    Objectives An in vitro study was performed to investigate the relationship between grey levels in dental cone beam CT (CBCT) and Hounsfield units (HU) in CBCT scanners. Methods A phantom containing 8 different materials of known composition and density was imaged with 11 different dental CBCT scanners and 2 medical CT scanners. The phantom was scanned under three conditions: phantom alone and phantom in a small and large water container. The reconstructed data were exported as Digital Imaging and Communications in Medicine (DICOM) and analysed with On Demand 3D® by Cybermed, Seoul, Korea. The relationship between grey levels and linear attenuation coefficients was investigated. Results It was demonstrated that a linear relationship between the grey levels and the attenuation coefficients of each of the materials exists at some “effective” energy. From the linear regression equation of the reference materials, attenuation coefficients were obtained for each of the materials and CT numbers in HU were derived using the standard equation. Conclusions HU can be derived from the grey levels in dental CBCT scanners using linear attenuation coefficients as an intermediate step. PMID:20729181

  14. Effects of uniform extracellular DC electric fields on excitability in rat hippocampal slices in vitro.

    PubMed

    Bikson, Marom; Inoue, Masashi; Akiyama, Hiroki; Deans, Jackie K; Fox, John E; Miyakawa, Hiroyoshi; Jefferys, John G R

    2004-05-15

    The effects of uniform steady state (DC) extracellular electric fields on neuronal excitability were characterized in rat hippocampal slices using field, intracellular and voltage-sensitive dye recordings. Small electric fields (1 s) changes in neuronal excitability. Electric fields perpendicular to the apical-dendritic axis did not induce somatic polarization, but did modulate orthodromic responses, indicating an effect on afferents. These results demonstrate that DC fields can modulate neuronal excitability in a time-dependent manner, with no clear threshold, as a result of interactions between neuronal compartments, the non-linear properties of the cell membrane, and effects on afferents.

  15. Fasting insulin levels and metabolic risk factors in type 2 diabetic patients at the first visit in Japan: a 10-year, nationwide, observational study (JDDM 28).

    PubMed

    Matsuba, Ikuro; Saito, Kazumi; Takai, Masahiko; Hirao, Koichi; Sone, Hirohito

    2012-09-01

    To investigate the relationship between fasting insulin levels and metabolic risk factors (MRFs) in type 2 diabetic patients at the first clinic/hospital visit in Japan over the years 2000 to 2009. In total, 4,798 drug-naive Japanese patients with type 2 diabetes were registered on their first clinic/hospital visits. Conventional clinical factors and fasting insulin levels were observed at baseline within the Japan Diabetes Clinical Data Management (JDDM) study between consecutive 2-year groups. Multiple linear regression analysis was performed using a model in which the dependent variable was fasting insulin values using various clinical explanatory variables. Fasting insulin levels were found to be decreasing from 2000 to 2009. Multiple linear regression analysis with the fasting insulin levels as the dependent variable showed that waist circumference (WC), BMI, mean blood pressure, triglycerides, and HDL cholesterol were significant, with WC and BMI as the main factors. ANCOVA after adjustment for age and fasting plasma glucose clearly shows the decreasing trend in fasting insulin levels and the increasing trend in BMI. During the 10-year observation period, the decreasing trend in fasting insulin was related to the slight increase in WC/BMI in type 2 diabetes. Low pancreatic β-cell reserve on top of a lifestyle background might be dependent on an increase in MRFs.

  16. Fasting Insulin Levels and Metabolic Risk Factors in Type 2 Diabetic Patients at the First Visit in Japan

    PubMed Central

    Matsuba, Ikuro; Saito, Kazumi; Takai, Masahiko; Hirao, Koichi; Sone, Hirohito

    2012-01-01

    OBJECTIVE To investigate the relationship between fasting insulin levels and metabolic risk factors (MRFs) in type 2 diabetic patients at the first clinic/hospital visit in Japan over the years 2000 to 2009. RESEARCH DESIGN AND METHODS In total, 4,798 drug-naive Japanese patients with type 2 diabetes were registered on their first clinic/hospital visits. Conventional clinical factors and fasting insulin levels were observed at baseline within the Japan Diabetes Clinical Data Management (JDDM) study between consecutive 2-year groups. Multiple linear regression analysis was performed using a model in which the dependent variable was fasting insulin values using various clinical explanatory variables. RESULTS Fasting insulin levels were found to be decreasing from 2000 to 2009. Multiple linear regression analysis with the fasting insulin levels as the dependent variable showed that waist circumference (WC), BMI, mean blood pressure, triglycerides, and HDL cholesterol were significant, with WC and BMI as the main factors. ANCOVA after adjustment for age and fasting plasma glucose clearly shows the decreasing trend in fasting insulin levels and the increasing trend in BMI. CONCLUSIONS During the 10-year observation period, the decreasing trend in fasting insulin was related to the slight increase in WC/BMI in type 2 diabetes. Low pancreatic β-cell reserve on top of a lifestyle background might be dependent on an increase in MRFs. PMID:22665215

  17. A meta-analysis of cambium phenology and growth: linear and non-linear patterns in conifers of the northern hemisphere.

    PubMed

    Rossi, Sergio; Anfodillo, Tommaso; Cufar, Katarina; Cuny, Henri E; Deslauriers, Annie; Fonti, Patrick; Frank, David; Gricar, Jozica; Gruber, Andreas; King, Gregory M; Krause, Cornelia; Morin, Hubert; Oberhuber, Walter; Prislan, Peter; Rathgeber, Cyrille B K

    2013-12-01

    Ongoing global warming has been implicated in shifting phenological patterns such as the timing and duration of the growing season across a wide variety of ecosystems. Linear models are routinely used to extrapolate these observed shifts in phenology into the future and to estimate changes in associated ecosystem properties such as net primary productivity. Yet, in nature, linear relationships may be special cases. Biological processes frequently follow more complex, non-linear patterns according to limiting factors that generate shifts and discontinuities, or contain thresholds beyond which responses change abruptly. This study investigates to what extent cambium phenology is associated with xylem growth and differentiation across conifer species of the northern hemisphere. Xylem cell production is compared with the periods of cambial activity and cell differentiation assessed on a weekly time scale on histological sections of cambium and wood tissue collected from the stems of nine species in Canada and Europe over 1-9 years per site from 1998 to 2011. The dynamics of xylogenesis were surprisingly homogeneous among conifer species, although dispersions from the average were obviously observed. Within the range analysed, the relationships between the phenological timings were linear, with several slopes showing values close to or not statistically different from 1. The relationships between the phenological timings and cell production were distinctly non-linear, and involved an exponential pattern. The trees adjust their phenological timings according to linear patterns. Thus, shifts of one phenological phase are associated with synchronous and comparable shifts of the successive phases. However, small increases in the duration of xylogenesis could correspond to a substantial increase in cell production. The findings suggest that the length of the growing season and the resulting amount of growth could respond differently to changes in environmental conditions.

  18. Measuring Earth's Magnetic Field Simply.

    ERIC Educational Resources Information Center

    Stewart, Gay B.

    2000-01-01

    Describes a method for measuring the earth's magnetic field using an empty toilet paper tube, copper wire, clear tape, a battery, a linear variable resistor, a small compass, cardboard, a protractor, and an ammeter. (WRM)

  19. Relationship between whole-body tumor burden, clinical phenotype, and quality of life in patients with neurofibromatosis.

    PubMed

    Merker, Vanessa L; Bredella, Miriam A; Cai, Wenli; Kassarjian, Ara; Harris, Gordon J; Muzikansky, Alona; Nguyen, Rosa; Mautner, Victor F; Plotkin, Scott R

    2014-06-01

    Patients with neurofibromatosis 1 (NF1), NF2, and schwannomatosis share a predisposition to develop multiple nerve sheath tumors. Previous studies have demonstrated that patients with NF1 and NF2 have reduced quality of life (QOL), but no studies have examined the relationship between whole-body tumor burden and QOL in these patients. We administered a QOL questionnaire (the SF-36) and a visual analog pain scale (VAS) to a previously described cohort of adult neurofibromatosis patients undergoing whole-body MRI. One-sample t-tests were used to compare norm-based SF-36 scores to weighted population means. Spearman correlation coefficients and multiple linear regression analyses controlling for demographic and disease-specific clinical variable were used to relate whole-body tumor volume to QOL scales. Two hundred forty-five patients (142 NF1, 53 NF2, 50 schwannomatosis) completed the study. Subjects showed deficits in selected subscales of the SF-36 compared to adjusted general population means. In bivariate analysis, increased tumor volume was significantly associated with pain in schwannomatosis patients, as measured by the SF-36 bodily pain subscale (rho = -0.287, P = 0.04) and VAS (rho = 0.34, P = 0.02). Regression models for NF2 patients showed a positive relationship between tumor burden and increased pain, as measured by the SF-36 (P = 0.008). Patients with NF1, NF2, and schwannomatosis suffer from reduced QOL, although only pain shows a clear relationship to patient's overall tumor burden. These findings suggest that internal tumor volume is not a primary contributor to QOL and emphasize the need for comprehensive treatment approaches that go beyond tumor-focused therapies such as surgery by including psychosocial interventions. © 2014 Wiley Periodicals, Inc.

  20. Wavelength dependent light absorption as a cost effective, real-time surrogate for ambient concentrations of polycyclic aromatic hydrocarbons

    NASA Astrophysics Data System (ADS)

    Brown, Richard J. C.; Butterfield, David M.; Goddard, Sharon L.; Hussain, Delwar; Quincey, Paul G.; Fuller, Gary W.

    2016-02-01

    Many monitoring stations used to assess ambient air concentrations of pollutants regulated by European air quality directives suffer from being expensive to establish and operate, and from their location being based on the results of macro-scale modelling exercises rather than measurement assessments in candidate locations. To address these issues for the monitoring of polycyclic aromatic hydrocarbons (PAHs), this study has used data from a combination of the ultraviolet and infrared channels of aethalometers (referred to as UV BC), operated as part of the UK Black Carbon Network, as a surrogate measurement. This has established a relationship between concentrations of the PAH regulated in Europe, benzo[a]pyrene (B[a]P), and the UV BC signal at locations where these measurements have been made together from 2008 to 2014. This relationship was observed to be non-linear. Relationships for individual site types were used to predict measured concentrations with, on average, 1.5% accuracy across all annual averages, and with only 1 in 36 of the predicted annual averages deviating from the measured annual average by more than the B[a]P data quality objective for uncertainty of 50% (at -65%, with the range excluding this value between + 38% and -37%). These relationships were then used to predict B[a]P concentrations at stations where UV BC measurement are made, but PAH measurements are not. This process produced results which reflected expectations based on knowledge of the pollution climate at these stations gained from the measurements of other air quality networks, or from nearby stations. The influence of domestic solid fuel heating was clear using this approach which highlighted Strabane in Northern Ireland as a station likely to be in excess of the air quality directive target value for B[a]P.

  1. Relationship Between Ecosystem Productivity and Photosynthetically Active Radiation for Northern Peatlands

    NASA Technical Reports Server (NTRS)

    Frolking, S. E.; Bubier, J. L.; Moore, T. R.; Ball, T.; Bellisario, L. M.; Bhardwaj, A.; Carroll, P.; Crill, P. M.; Lafleur, P. M.; McCaughey, J. H.; hide

    1998-01-01

    We analyzed the relationship between net ecosystem exchange of carbon dioxide (NEE) and irradiance (as photosynthetic photon flux density or PPFD), using published and unpublished data that have been collected during midgrowing season for carbon balance studies at seven peatlands in North America and Europe, NEE measurements included both eddy-correlation tower and clear, static chamber methods, which gave very similar results. Data were analyzed by site, as aggregated data sets by peatland type (bog, poor fen, rich fen, and all fens) and as a single aggregated data set for all peatlands. In all cases, a fit with a rectangular hyperbola (NEE = alpha PPFD P(sub max)/(alpha PPFD + P(sub max) + R) better described the NEE-PPFD relationship than did a linear fit (NEE = beta PPFD + R). Poor and rich fens generally had similar NEE-PPFD relationships, while bogs had lower respiration rates (R = -2.0 micro mol m(exp -2) s(exp -1) for bogs and -2.7 micro mol m(exp -2) s(exp -1)) for fens) and lower NEE at moderate and high light levels (P(sub max)= 5.2 micro mol m(exp -2) s(exp -1) for bogs and 10.8 micro mol m(exp -2) s(exp -1) for fens). As a single class, northern peatlands had much smaller ecosystem respiration (R = -2.4 micro mol m(exp -2) s(exp -1)) and NEE rates (alpha = 0.020 and P(sub max)= 9.2 micro mol m(exp -2) s(exp -1)) than the upland ecosystems (closed canopy forest, grassland, and cropland). Despite this low productivity, northern peatland soil carbon pools are generally 5-50 times larger than upland ecosystems because of slow rates of decomposition caused by litter quality and anaerobic, cold soils.

  2. Validating the relationship between 3-dimensional body acceleration and oxygen consumption in trained Steller sea lions.

    PubMed

    Volpov, Beth L; Rosen, David A S; Trites, Andrew W; Arnould, John P Y

    2015-08-01

    We tested the ability of overall dynamic body acceleration (ODBA) to predict the rate of oxygen consumption ([Formula: see text]) in freely diving Steller sea lions (Eumetopias jubatus) while resting at the surface and diving. The trained sea lions executed three dive types-single dives, bouts of multiple long dives with 4-6 dives per bout, or bouts of multiple short dives with 10-12 dives per bout-to depths of 40 m, resulting in a range of activity and oxygen consumption levels. Average metabolic rate (AMR) over the dive cycle or dive bout calculated was calculated from [Formula: see text]. We found that ODBA could statistically predict AMR when data from all dive types were combined, but that dive type was a significant model factor. However, there were no significant linear relationships between AMR and ODBA when data for each dive type were analyzed separately. The potential relationships between AMR and ODBA were not improved by including dive duration, food consumed, proportion of dive cycle spent submerged, or number of dives per bout. It is not clear whether the lack of predictive power within dive type was due to low statistical power, or whether it reflected a true absence of a relationship between ODBA and AMR. The average percent error for predicting AMR from ODBA was 7-11 %, and standard error of the estimated AMR was 5-32 %. Overall, the extensive range of dive behaviors and physiological conditions we tested indicated that ODBA was not suitable for estimating AMR in the field due to considerable error and the inconclusive effects of dive type.

  3. Race-based rejection sensitivity partially accounts for the relationship between racial discrimination and distressing attenuated positive psychotic symptoms.

    PubMed

    Anglin, Deidre M; Greenspoon, Michelle; Lighty, Quenesha; Ellman, Lauren M

    2016-10-01

    Self-reported experiences of racial discrimination have been associated with a continuum of psychotic experiences in racial and ethnic minority populations; however, the underlying mechanisms of this relationship are not yet clear. Race-based rejection sensitivity (RS-race) has been associated with thought intrusions about being the target of racial discrimination; therefore, the present study aimed to determine whether RS-race accounts for the relationship between racial discrimination and psychotic-like experiences in racial and ethnic minority populations. A sample of 644 young adults from a US urban, predominantly immigrant, and racial and ethnic minority population was administered a self-report inventory of psychosis risk (i.e. Prodromal Questionnaire (PQ) ), providing a dimensional assessment of the total number of attenuated positive psychotic symptoms experienced as distressing (APPS-distress). Participants also completed the Experiences of Discrimination Questionnaire and the Rejection Sensitivity Questionnaire-Race. Hierarchical linear regression analyses revealed that RS-race and racial discrimination were both significantly related to higher levels of APPS-distress. Bootstrapping analyses of indirect effects indicated that RS-race partially accounted for the relationship between racial discrimination and APPS-distress. Although the cross-sectional nature of the data limits conclusions about causal inference, our findings do suggest that racial discrimination and RS-race may both be important for understanding risk for distress in the psychotic spectrum among racial and ethnic minority young adults. Some individuals who report racial discrimination may be more vulnerable to APPS-distress in part because they are anxiously anticipating being racially slighted, and this should be explored further in prospective clinical high-risk studies. © 2014 Wiley Publishing Asia Pty Ltd.

  4. Regional variability among nonlinear chlorophyll-phosphorus relationships in lakes

    USGS Publications Warehouse

    Filstrup, Christopher T.; Wagner, Tyler; Soranno, Patricia A.; Stanley, Emily H.; Stow, Craig A.; Webster, Katherine E.; Downing, John A.

    2014-01-01

    The relationship between chlorophyll a (Chl a) and total phosphorus (TP) is a fundamental relationship in lakes that reflects multiple aspects of ecosystem function and is also used in the regulation and management of inland waters. The exact form of this relationship has substantial implications on its meaning and its use. We assembled a spatially extensive data set to examine whether nonlinear models are a better fit for Chl a—TP relationships than traditional log-linear models, whether there were regional differences in the form of the relationships, and, if so, which regional factors were related to these differences. We analyzed a data set from 2105 temperate lakes across 35 ecoregions by fitting and comparing two different nonlinear models and one log-linear model. The two nonlinear models fit the data better than the log-linear model. In addition, the parameters for the best-fitting model varied among regions: the maximum and lower Chl aasymptotes were positively and negatively related to percent regional pasture land use, respectively, and the rate at which chlorophyll increased with TP was negatively related to percent regional wetland cover. Lakes in regions with more pasture fields had higher maximum chlorophyll concentrations at high TP concentrations but lower minimum chlorophyll concentrations at low TP concentrations. Lakes in regions with less wetland cover showed a steeper Chl a—TP relationship than wetland-rich regions. Interpretation of Chl a—TP relationships depends on regional differences, and theory and management based on a monolithic relationship may be inaccurate.

  5. A phenomenological biological dose model for proton therapy based on linear energy transfer spectra.

    PubMed

    Rørvik, Eivind; Thörnqvist, Sara; Stokkevåg, Camilla H; Dahle, Tordis J; Fjaera, Lars Fredrik; Ytre-Hauge, Kristian S

    2017-06-01

    The relative biological effectiveness (RBE) of protons varies with the radiation quality, quantified by the linear energy transfer (LET). Most phenomenological models employ a linear dependency of the dose-averaged LET (LET d ) to calculate the biological dose. However, several experiments have indicated a possible non-linear trend. Our aim was to investigate if biological dose models including non-linear LET dependencies should be considered, by introducing a LET spectrum based dose model. The RBE-LET relationship was investigated by fitting of polynomials from 1st to 5th degree to a database of 85 data points from aerobic in vitro experiments. We included both unweighted and weighted regression, the latter taking into account experimental uncertainties. Statistical testing was performed to decide whether higher degree polynomials provided better fits to the data as compared to lower degrees. The newly developed models were compared to three published LET d based models for a simulated spread out Bragg peak (SOBP) scenario. The statistical analysis of the weighted regression analysis favored a non-linear RBE-LET relationship, with the quartic polynomial found to best represent the experimental data (P = 0.010). The results of the unweighted regression analysis were on the borderline of statistical significance for non-linear functions (P = 0.053), and with the current database a linear dependency could not be rejected. For the SOBP scenario, the weighted non-linear model estimated a similar mean RBE value (1.14) compared to the three established models (1.13-1.17). The unweighted model calculated a considerably higher RBE value (1.22). The analysis indicated that non-linear models could give a better representation of the RBE-LET relationship. However, this is not decisive, as inclusion of the experimental uncertainties in the regression analysis had a significant impact on the determination and ranking of the models. As differences between the models were observed for the SOBP scenario, both non-linear LET spectrum- and linear LET d based models should be further evaluated in clinically realistic scenarios. © 2017 American Association of Physicists in Medicine.

  6. Age at menarche, total mortality and mortality from ischaemic heart disease and stroke: the Adventist Health Study, 1976–88

    PubMed Central

    Jacobsen, B K; Oda, K; Knutsen, S F; Fraser, G E

    2009-01-01

    Background Little is known about the relationship between age at menarche and total mortality and mortality from ischaemic heart disease and stroke. Methods A cohort study of 19 462 Californian Seventh-Day Adventist women followed-up from 1976 to 1988. A total of 3313 deaths occurred during follow-up, of which 809 were due to ischaemic heart disease and 378 due to stroke. Results An early menarche was associated with increased total mortality (P-value for linear trend <0.001), ischaemic heart disease (P-value for linear trend = 0.01) and stroke (P-value for linear trend = 0.02) mortality. There were, however, also some indications of an increased ischaemic heart disease mortality in women aged 16–18 at menarche (5% of the women). When assessed as a linear relationship, a 1-year delay in menarche was associated with 4.5% (95% CI 2.3–6.7) lower total mortality. The association was stronger for ischaemic heart disease [6.0% (95% CI 1.2–10.6)] and stroke [8.6% (95% CI 1.6–15.1)] mortality. Conclusions The results suggest that there is a linear, inverse relationship between age at menarche and total mortality as well as with ischaemic heart disease and stroke mortality. PMID:19188208

  7. Age at menarche, total mortality and mortality from ischaemic heart disease and stroke: the Adventist Health Study, 1976-88.

    PubMed

    Jacobsen, B K; Oda, K; Knutsen, S F; Fraser, G E

    2009-02-01

    Little is known about the relationship between age at menarche and total mortality and mortality from ischaemic heart disease and stroke. A cohort study of 19 462 Californian Seventh-Day Adventist women followed-up from 1976 to 1988. A total of 3313 deaths occurred during follow-up, of which 809 were due to ischaemic heart disease and 378 due to stroke. An early menarche was associated with increased total mortality (P-value for linear trend <0.001), ischaemic heart disease (P-value for linear trend = 0.01) and stroke (P-value for linear trend = 0.02) mortality. There were, however, also some indications of an increased ischaemic heart disease mortality in women aged 16-18 at menarche (5% of the women). When assessed as a linear relationship, a 1-year delay in menarche was associated with 4.5% (95% CI 2.3-6.7) lower total mortality. The association was stronger for ischaemic heart disease [6.0% (95% CI 1.2-10.6)] and stroke [8.6% (95% CI 1.6-15.1)] mortality. The results suggest that there is a linear, inverse relationship between age at menarche and total mortality as well as with ischaemic heart disease and stroke mortality.

  8. Can we detect a nonlinear response to temperature in European plant phenology?

    PubMed

    Jochner, Susanne; Sparks, Tim H; Laube, Julia; Menzel, Annette

    2016-10-01

    Over a large temperature range, the statistical association between spring phenology and temperature is often regarded and treated as a linear function. There are suggestions that a sigmoidal relationship with definite upper and lower limits to leaf unfolding and flowering onset dates might be more realistic. We utilised European plant phenological records provided by the European phenology database PEP725 and gridded monthly mean temperature data for 1951-2012 calculated from the ENSEMBLES data set E-OBS (version 7.0). We analysed 568,456 observations of ten spring flowering or leafing phenophases derived from 3657 stations in 22 European countries in order to detect possible nonlinear responses to temperature. Linear response rates averaged for all stations ranged between -7.7 (flowering of hazel) and -2.7 days °C -1 (leaf unfolding of beech and oak). A lower sensitivity at the cooler end of the temperature range was detected for most phenophases. However, a similar lower sensitivity at the warmer end was not that evident. For only ∼14 % of the station time series (where a comparison between linear and nonlinear model was possible), nonlinear models described the relationship significantly better than linear models. Although in most cases simple linear models might be still sufficient to predict future changes, this linear relationship between phenology and temperature might not be appropriate when incorporating phenological data of very cold (and possibly very warm) environments. For these cases, extrapolations on the basis of linear models would introduce uncertainty in expected ecosystem changes.

  9. Network diffusion accurately models the relationship between structural and functional brain connectivity networks

    PubMed Central

    Abdelnour, Farras; Voss, Henning U.; Raj, Ashish

    2014-01-01

    The relationship between anatomic connectivity of large-scale brain networks and their functional connectivity is of immense importance and an area of active research. Previous attempts have required complex simulations which model the dynamics of each cortical region, and explore the coupling between regions as derived by anatomic connections. While much insight is gained from these non-linear simulations, they can be computationally taxing tools for predicting functional from anatomic connectivities. Little attention has been paid to linear models. Here we show that a properly designed linear model appears to be superior to previous non-linear approaches in capturing the brain’s long-range second order correlation structure that governs the relationship between anatomic and functional connectivities. We derive a linear network of brain dynamics based on graph diffusion, whereby the diffusing quantity undergoes a random walk on a graph. We test our model using subjects who underwent diffusion MRI and resting state fMRI. The network diffusion model applied to the structural networks largely predicts the correlation structures derived from their fMRI data, to a greater extent than other approaches. The utility of the proposed approach is that it can routinely be used to infer functional correlation from anatomic connectivity. And since it is linear, anatomic connectivity can also be inferred from functional data. The success of our model confirms the linearity of ensemble average signals in the brain, and implies that their long-range correlation structure may percolate within the brain via purely mechanistic processes enacted on its structural connectivity pathways. PMID:24384152

  10. Relationship Between Depression and Lower Urinary Tract Symptoms Secondary to Benign Prostatic Hyperplasia.

    PubMed

    Dunphy, Claire; Laor, Leanna; Te, Alexis; Kaplan, Steven; Chughtai, Bilal

    2015-01-01

    This article provides an overview of current data on the relationship between depression and lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia (BPH), with a focus on pathophysiology and patient management implications. Review of the literature indicated a clear relationship between LUTS secondary to BPH and depression. It is unknown whether this relationship is bidirectional or unidirectional. Depression is associated with the impact of LUTS on quality of life in men with BPH. Research suggests that depression alters the experience of LUTS in this population. Medical and surgical treatments for BPH may impact quality of life and, therefore, depression. Results conflict on the exact nature of the relationship examined, and on the extent to which the relationship may be attributed to physiological factors such as inflammation. Practicing clinicians should consider using a brief self-administered scale to assess for depression in patients with BPH. There is a clear need for additional research to decisively determine the nature of the relationship between LUTS secondary to BPH and depression, as well as the extent to which change in either condition may be affected by the other.

  11. Evaluating and Improving the SAMA (Segmentation Analysis and Market Assessment) Recruiting Model

    DTIC Science & Technology

    2015-06-01

    and rewarding me with your love every day. xx THIS PAGE INTENTIONALLY LEFT BLANK 1 I. INTRODUCTION A. THE UNITED STATES ARMY RECRUITING...the relationship between the calculated SAMA potential and the actual 2014 performance. The scatterplot in Figure 8 shows a strong linear... relationship between the SAMA calculated potential and the contracting achievement for 2014, with an R-squared value of 0.871. Simple Linear Regression of

  12. Prediction of trivalent actinide amino(poly)carboxylate complex stability constants using linear free energy relationships with the lanthanide series

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Uhnak, Nic E.

    Prediction of Trivalent Actinide Amino(poly)carboxylate Complex Stability Constants Using Linear Free Energy Relationships with the Lanthanide Series Alternative title: LFER Based Prediction of An(III) APC Stability Constants There is a gap in the literature regarding the complexation of amino(poly)carboxylate (APC) ligands with trivalent actinides (An(III))). The chemistry of the An(III) is nearly identical to that of the trivalent lanthanides Lns, but the An(III) express a slight enhancement when binding APC ligands. Presented in this report is a simple method of predicting the stability constants of the An(III), Pu, Am, Cm, Bk and Cf by using linear free energy relationships (LFER)more » of the An and the lanthanide (Ln) series for 91 APCs. This method produced An stability constants within uncertainty to available literature values for most ligands.« less

  13. Relationship between changes in vasomotor symptoms and changes in menopause-specific quality of life and sleep parameters.

    PubMed

    Pinkerton, JoAnn V; Abraham, Lucy; Bushmakin, Andrew G; Cappelleri, Joseph C; Komm, Barry S

    2016-10-01

    This study characterizes and quantifies the relationship of vasomotor symptoms (VMS) of menopause with menopause-specific quality of life (MSQOL) and sleep parameters to help predict treatment outcomes and inform treatment decision-making. Data were derived from a 12-week randomized, double-blind, placebo-controlled phase 3 trial that evaluated effects of two doses of conjugated estrogens/bazedoxifene on VMS in nonhysterectomized postmenopausal women (N = 318, mean age = 53.39) experiencing at least seven moderate to severe hot flushes (HFs) per day or at least 50 per week. Repeated measures models were used to determine relationships between HF frequency and severity and outcomes on the Menopause-Specific Quality of Life questionnaire and the Medical Outcomes Study sleep scale. Sensitivity analyses were performed to check assumptions of linearity between VMS and outcomes. Frequency and severity of HFs showed approximately linear relationships with MSQOL and sleep parameters. Sensitivity analyses supported assumptions of linearity. The largest changes associated with a reduction of five HFs and a 0.5-point decrease in severity occurred in the Menopause-Specific Quality of Life vasomotor functioning domain (0.78 for number of HFs and 0.98 for severity) and the Medical Outcomes Study sleep disturbance (7.38 and 4.86) and sleep adequacy (-5.60 and -4.66) domains and the two overall sleep problems indices (SPI: 5.17 and 3.63; SPII: 5.82 and 3.83). Frequency and severity of HFs have an approximately linear relationship with MSQOL and sleep parameters-that is, improvements in HFs are associated with improvements in MSQOL and sleep. Such relationships may enable clinicians to predict changes in sleep and MSQOL expected from various VMS treatments.

  14. Observation of glassy state relaxation during annealing of frozen sugar solutions by X-ray computed tomography.

    PubMed

    Nakagawa, Kyuya; Tamiya, Shinri; Do, Gabsoo; Kono, Shinji; Ochiai, Takaaki

    2018-06-01

    Glassy phase formation in a frozen product determines various properties of the freeze-dried products. When an aqueous solution is subjected to freezing, a glassy phase forms as a consequence of freeze-concentration. During post-freezing annealing, the relaxation of the glassy phase and the ripening of ice crystals (i.e. Ostwald ripening) spontaneously occur, where the kinetics are controlled by the annealing and glass transition temperatures. This study was motivated to observe the progress of glassy state relaxation separate from ice coarsening during annealing. X-ray computed tomography (CT) was used to observe a frozen and post-freezing annealed solutions by using monochromatized X-ray from the synchrotron radiation. CT images were successfully obtained, and the frozen matrix were analyzed based on the gray level values that were equivalent to the linear X-ray attenuation coefficients of the observed matters. The CT images obtained from rapidly frozen sucrose and dextrin solutions with different concentrations gave clear linear relationships between the linear X-ray attenuation coefficients values and the solute concentrations. It was confirmed that the glassy state relaxation progressed as increasing annealing time, and this trend was larger in the order of the glass transition temperature of the maximally freeze-concentrated phase. The sucrose-water system required nearly 20 h of annealing time at -5 °C for the completion of the glassy phase relaxation, whereas dextrin-water systems required much longer periods because of their higher glass transition temperatures. The trends of ice coarsening, however, did not perfectly correspond to the trends of the relaxation, suggesting that the glassy phase relaxation and Ostwald ripening would jointly control the ice crystal growth/ripening kinetics, and the dominant mechanism differed by the annealing stage. Copyright © 2018 Elsevier B.V. All rights reserved.

  15. Dependence and independence of survival parameters on linear energy transfer in cells and tissues

    PubMed Central

    Ando, Koichi; Goodhead, Dudley T.

    2016-01-01

    Carbon-ion radiotherapy has been used to treat more than 9000 cancer patients in the world since 1994. Spreading of the Bragg peak is necessary for carbon-ion radiotherapy, and is designed based on the linear–quadratic model that is commonly used for photon therapy. Our recent analysis using in vitro cell kills and in vivo mouse tissue reaction indicates that radiation quality affects mainly the alpha terms, but much less the beta terms, which raises the question of whether this is true in other biological systems. Survival parameters alpha and beta for 45 in vitro mammalian cell lines were obtained by colony formation after irradiation with carbon ions, fast neutrons and X-rays. Relationships between survival parameters and linear energy transfer (LET) below 100 keV/μm were obtained for 4 mammalian cell lines. Mouse skin reaction and tumor growth delay were measured after fractionated irradiation. The Fe-plot provided survival parameters of the tissue reactions. A clear separation between X-rays and high-LET radiation was observed for alpha values, but not for beta values. Alpha values/terms increased with increasing LET in any cells and tissues studied, while beta did not show a systematic change. We have found a puzzle or contradiction in common interpretations of the linear-quadratic model that causes us to question whether the model is appropriate for interpreting biological effectiveness of high-LET radiation up to 500 keV/μm, probably because of inconsistency in the concept of damage interaction. A repair saturation model proposed here was good enough to fit cell kill efficiency by radiation of wide-ranged LET. A model incorporating damage complexity and repair saturation would be suitable for heavy-ion radiotherapy. PMID:27380803

  16. Implications of discontinuous elevation gradients on fragmentation and restoration in patterned wetlands

    USGS Publications Warehouse

    Zweig, Christa L.; Reichert, Brian E.; Kitchens, Wiley M.

    2011-01-01

    Large wetlands around the world face the possibility of degradation, not only from complete conversion, but also from subtle changes in their structure and function. While fragmentation and isolation of wetlands within heterogeneous landscapes has received much attention, the disruption of spatial patterns/processes within large wetland systems and the resulting fragmentation of community components are less well documented. A greater understanding of pattern/process relationships and landscape gradients, and what occurs when they are altered, could help avoid undesirable consequences of restoration actions. The objective of this study is to determine the amount of fragmentation of sawgrass ridges due to artificial impoundment of water and how that may be differentially affected by spatial position relative to north and south levees. We also introduce groundbreaking evidence of landscape-level discontinuous elevation gradients within WCA3AS by comparing generalized linear and generalized additive models. These relatively abrupt breaks in elevation may have non-linear effects on hydrology and vegetation communities and would be crucial in restoration considerations. Modeling suggests there are abrupt breaks in elevation as a function of northing (Y-coordinate). Fragmentation indices indicate that fragmentation is a function of elevation and easting (X-coordinate), and that fragmentation has increased from 1988-2002. When landscapes change and the changes are compounded by non-linear landscape variables that are described herein, the maintenance processes change with them, creating a degraded feedback loop that alters the system's response to structuring variables and diminishes our ability to predict the effects of restoration projects or climate change. Only when these landscape variables and linkages are clearly defined can we predict the response to potential perturbations and apply the knowledge to other landscape-level wetland systems in need of future restoration.

  17. Visible photoluminescence of color centers in LiF crystals for absorbed dose evaluation in clinical dosimetry

    NASA Astrophysics Data System (ADS)

    Villarreal-Barajas, J. E.; Piccinini, M.; Vincenti, M. A.; Bonfigli, F.; Khan, R. F.; Montereali, R. M.

    2015-04-01

    Among insulating materials, lithium fluoride (LiF) has been successfully used as ionizing radiation dosemeter for more than 60 years. Thermoluminescence (TL) has been the most commonly used reading technique to evaluate the absorbed dose. Lately, optically stimulated luminescence (OSL) of visible emitting color centers (CCs) has also been explored in pure and doped LiF. This work focuses on the experimental behaviour of nominally pure LiF crystals dosemeters for 6 MV x rays at low doses based on photoluminescence (PL) of radiation induced CCs. Polished LiF crystals were irradiated using 6 MV x rays produced by a clinical linear accelerator. The doses (absorbed dose to water) covered the 1-100 Gy range. Optical absorption spectra show stable formation of primary F defects up to a maximum concentration of 2×1016 cm-3, while no significant M absorption band at around 450 nm was detected. On the other hand, under Argon laser excitation at 458 nm, PL spectra of the irradiated LiF crystals clearly exhibited the characteristic F2 and F+3 visible broad emission bands. Their sum intensity is linearly proportional to the absorbed dose in the investigated range. PL integrated intensity was also measured using a conventional fluorescence optical microscope under blue lamp illumination. The relationship between the absorbed dose and the integrated F2 and F+3 PL intensities, represented by the net average pixel number in the optical fluorescence images, is also fairly linear. Even at the low point defect densities obtained at the investigated doses, these preliminary experimental results are encouraging for further investigation of CCs PL in LiF crystals for clinical dosimetry.

  18. Stunting at birth: recognition of early-life linear growth failure in the western highlands of Guatemala.

    PubMed

    Solomons, Noel W; Vossenaar, Marieke; Chomat, Anne-Marie; Doak, Colleen M; Koski, Kristine G; Scott, Marilyn E

    2015-07-01

    Measurements of length at birth, or in the neonatal period, are challenging to obtain and often discounted for lack of validity. Hence, classical 'under-5' stunting rates have been derived from surveys on children from 6 to 59 months of age. Guatemala has a high prevalence of stunting (49.8%), but the age of onset of growth failure is not clearly defined. The objective of the study was to assess length-for-age within the first 1.5 months of life among Guatemalan infants. As part of a cross-sectional observational study, supine length was measured in young infants. Mothers' height was measured. Length-for-age Z-scores (HAZ) were generated and stunting was defined as HAZ <-2 using WHO growth standards. Eight rural, indigenous Mam-Mayan villages (n 200, 100% of Mayan indigenous origin) and an urban clinic of Quetzaltenango (n 106, 27% of Mayan indigenous origin), Guatemala. Three hundred and six newborns with a median age of 19 d. The median rural HAZ was -1.56 and prevalence of stunting was 38%; the respective urban values were -1.41 and 25%. Linear regression revealed no relationship between infant age and HAZ (r = 0.101, r(2) = 0.010, P = 0.077). Maternal height explained 3% of the variability in HAZ (r = 0.171, r(2) = 0.029, P = 0.003). Stunting must be carried over from in utero growth retardation in short-stature Guatemalan mothers. As linear growth failure in this setting begins in utero, its prevention must be linked to maternal care strategies during gestation, or even before. A focus on maternal nutrition and health in an intergenerational dimension is needed to reduce its prevalence.

  19. Spatial Characteristics of Small Green Spaces' Mitigating Effects on Microscopic Urban Heat Islands

    NASA Astrophysics Data System (ADS)

    Park, J.; Lee, D. K.; Jeong, W.; Kim, J. H.; Huh, K. Y.

    2015-12-01

    The purpose of the study is to find small greens' disposition, types and sizes to reduce air temperature effectively in urban blocks. The research sites were six high developed blocks in Seoul, Korea. Air temperature was measured with mobile loggers in clear daytime during summer, from August to September, at screen level. Also the measurement repeated over three times a day during three days by walking and circulating around the experimental blocks and the control blocks at the same time. By analyzing spatial characteristics, the averaged air temperatures were classified with three spaces, sunny spaces, building-shaded spaces and small green spaces by using Kruskal-Wallis Test; and small green spaces in 6 blocks were classified into their outward forms, polygonal or linear and single or mixed. The polygonal and mixed types of small green spaces mitigated averaged air temperature of each block which they belonged with a simple linear regression model with adjusted R2 = 0.90**. As the area and volume of these types increased, the effect of air temperature reduction (ΔT; Air temperature difference between sunny space and green space in a block) also increased in a linear relationship. The experimental range of this research is 100m2 ~ 2,000m2 of area, and 1,000m3 ~ 10,000m3 of volume of small green space. As a result, more than 300m2 and 2,300m3 of polygonal green spaces with mixed vegetation is required to lower 1°C; 650m2 and 5,000m3 of them to lower 2°C; about 2,000m2 and about 10,000m3 of them to lower 4°C air temperature reduction in an urban block.

  20. 7 CFR 1.74 - Basis for special working relationships.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Production of Television Films § 1.74 Basis for special working relationships. The Department and its agencies may lend special assistance on television films when it is clearly evident that public interests...

  1. 7 CFR 1.74 - Basis for special working relationships.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Production of Television Films § 1.74 Basis for special working relationships. The Department and its agencies may lend special assistance on television films when it is clearly evident that public interests...

  2. 7 CFR 1.74 - Basis for special working relationships.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Production of Television Films § 1.74 Basis for special working relationships. The Department and its agencies may lend special assistance on television films when it is clearly evident that public interests...

  3. 7 CFR 1.74 - Basis for special working relationships.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Production of Television Films § 1.74 Basis for special working relationships. The Department and its agencies may lend special assistance on television films when it is clearly evident that public interests...

  4. Comparison of linear, skewed-linear, and proportional hazard models for the analysis of lambing interval in Ripollesa ewes.

    PubMed

    Casellas, J; Bach, R

    2012-06-01

    Lambing interval is a relevant reproductive indicator for sheep populations under continuous mating systems, although there is a shortage of selection programs accounting for this trait in the sheep industry. Both the historical assumption of small genetic background and its unorthodox distribution pattern have limited its implementation as a breeding objective. In this manuscript, statistical performances of 3 alternative parametrizations [i.e., symmetric Gaussian mixed linear (GML) model, skew-Gaussian mixed linear (SGML) model, and piecewise Weibull proportional hazard (PWPH) model] have been compared to elucidate the preferred methodology to handle lambing interval data. More specifically, flock-by-flock analyses were performed on 31,986 lambing interval records (257.3 ± 0.2 d) from 6 purebred Ripollesa flocks. Model performances were compared in terms of deviance information criterion (DIC) and Bayes factor (BF). For all flocks, PWPH models were clearly preferred; they generated a reduction of 1,900 or more DIC units and provided BF estimates larger than 100 (i.e., PWPH models against linear models). These differences were reduced when comparing PWPH models with different number of change points for the baseline hazard function. In 4 flocks, only 2 change points were required to minimize the DIC, whereas 4 and 6 change points were needed for the 2 remaining flocks. These differences demonstrated a remarkable degree of heterogeneity across sheep flocks that must be properly accounted for in genetic evaluation models to avoid statistical biases and suboptimal genetic trends. Within this context, all 6 Ripollesa flocks revealed substantial genetic background for lambing interval with heritabilities ranging between 0.13 and 0.19. This study provides the first evidence of the suitability of PWPH models for lambing interval analysis, clearly discarding previous parametrizations focused on mixed linear models.

  5. Convex set and linear mixing model

    NASA Technical Reports Server (NTRS)

    Xu, P.; Greeley, R.

    1993-01-01

    A major goal of optical remote sensing is to determine surface compositions of the earth and other planetary objects. For assessment of composition, single pixels in multi-spectral images usually record a mixture of the signals from various materials within the corresponding surface area. In this report, we introduce a closed and bounded convex set as a mathematical model for linear mixing. This model has a clear geometric implication because the closed and bounded convex set is a natural generalization of a triangle in n-space. The endmembers are extreme points of the convex set. Every point in the convex closure of the endmembers is a linear mixture of those endmembers, which is exactly how linear mixing is defined. With this model, some general criteria for selecting endmembers could be described. This model can lead to a better understanding of linear mixing models.

  6. Relationships between Academic Intrinsic Motivation and Anxiety in Children and Young Adolescents.

    ERIC Educational Resources Information Center

    Gottfried, Adele Eskeles

    1982-01-01

    Investigates the relationship between academic intrinsic motivation and anxiety when these variables are differentiated into academic subject areas. Results showed fourth and seventh graders differed in the pattern of relationships. Results clearly show academic intrinsic motivation and anxiety are negatively related and differentiated according…

  7. Assessing Decision Making in Young Adult Romantic Relationships

    ERIC Educational Resources Information Center

    Vennum, Amber; Fincham, Frank D.

    2011-01-01

    Romantic relationships among young adults are rich with ambiguity and without a clear, universal progression emphasizing the need for active decision making. Lack of active decision making in romantic relationships can lead to increases in constraints (e.g. pregnancy, shared living space or finances) that promote the continuation of relationships…

  8. To Honor Fechner and Obey Stevens: Relationships between Psychophysical and Neural Nonlinearities

    ERIC Educational Resources Information Center

    Billock, Vincent A.; Tsou, Brian H.

    2011-01-01

    G. T. Fechner (1860/1966) famously described two kinds of psychophysics: "Outer psychophysics" captures the black box relationship between sensory inputs and perceptual magnitudes, whereas "inner psychophysics" contains the neural transformations that Fechner's outer psychophysics elided. The relationship between the two has never been clear.…

  9. The Relationship between Counselors' Multicultural Counseling Competence and Poverty Beliefs

    ERIC Educational Resources Information Center

    Clark, Madeline Elizabeth

    2016-01-01

    The relationship between increased levels of poverty and decreased levels of psychological wellbeing and overall wellness is well documented. Although poverty clearly impacts mental health and wellness, little research in counseling has been conducted exploring the poverty attitudes of counselors. This study explored the relationship between…

  10. A Novel Nonlinear Piezoelectric Energy Harvesting System Based on Linear-Element Coupling: Design, Modeling and Dynamic Analysis.

    PubMed

    Zhou, Shengxi; Yan, Bo; Inman, Daniel J

    2018-05-09

    This paper presents a novel nonlinear piezoelectric energy harvesting system which consists of linear piezoelectric energy harvesters connected by linear springs. In principle, the presented nonlinear system can improve broadband energy harvesting efficiency where magnets are forbidden. The linear spring inevitably produces the nonlinear spring force on the connected harvesters, because of the geometrical relationship and the time-varying relative displacement between two adjacent harvesters. Therefore, the presented nonlinear system has strong nonlinear characteristics. A theoretical model of the presented nonlinear system is deduced, based on Euler-Bernoulli beam theory, Kirchhoff’s law, piezoelectric theory and the relevant geometrical relationship. The energy harvesting enhancement of the presented nonlinear system (when n = 2, 3) is numerically verified by comparing with its linear counterparts. In the case study, the output power area of the presented nonlinear system with two and three energy harvesters is 268.8% and 339.8% of their linear counterparts, respectively. In addition, the nonlinear dynamic response characteristics are analyzed via bifurcation diagrams, Poincare maps of the phase trajectory, and the spectrum of the output voltage.

  11. Transmission of linear regression patterns between time series: From relationship in time series to complex networks

    NASA Astrophysics Data System (ADS)

    Gao, Xiangyun; An, Haizhong; Fang, Wei; Huang, Xuan; Li, Huajiao; Zhong, Weiqiong; Ding, Yinghui

    2014-07-01

    The linear regression parameters between two time series can be different under different lengths of observation period. If we study the whole period by the sliding window of a short period, the change of the linear regression parameters is a process of dynamic transmission over time. We tackle fundamental research that presents a simple and efficient computational scheme: a linear regression patterns transmission algorithm, which transforms linear regression patterns into directed and weighted networks. The linear regression patterns (nodes) are defined by the combination of intervals of the linear regression parameters and the results of the significance testing under different sizes of the sliding window. The transmissions between adjacent patterns are defined as edges, and the weights of the edges are the frequency of the transmissions. The major patterns, the distance, and the medium in the process of the transmission can be captured. The statistical results of weighted out-degree and betweenness centrality are mapped on timelines, which shows the features of the distribution of the results. Many measurements in different areas that involve two related time series variables could take advantage of this algorithm to characterize the dynamic relationships between the time series from a new perspective.

  12. Transmission of linear regression patterns between time series: from relationship in time series to complex networks.

    PubMed

    Gao, Xiangyun; An, Haizhong; Fang, Wei; Huang, Xuan; Li, Huajiao; Zhong, Weiqiong; Ding, Yinghui

    2014-07-01

    The linear regression parameters between two time series can be different under different lengths of observation period. If we study the whole period by the sliding window of a short period, the change of the linear regression parameters is a process of dynamic transmission over time. We tackle fundamental research that presents a simple and efficient computational scheme: a linear regression patterns transmission algorithm, which transforms linear regression patterns into directed and weighted networks. The linear regression patterns (nodes) are defined by the combination of intervals of the linear regression parameters and the results of the significance testing under different sizes of the sliding window. The transmissions between adjacent patterns are defined as edges, and the weights of the edges are the frequency of the transmissions. The major patterns, the distance, and the medium in the process of the transmission can be captured. The statistical results of weighted out-degree and betweenness centrality are mapped on timelines, which shows the features of the distribution of the results. Many measurements in different areas that involve two related time series variables could take advantage of this algorithm to characterize the dynamic relationships between the time series from a new perspective.

  13. Linear frequency tuning in an LC-resonant system using a C-V response controllable MEMS varactor

    NASA Astrophysics Data System (ADS)

    Han, Chang-Hoon; Yoon, Yong-Hoon; Ko, Seung-Deok; Seo, Min-Ho; Yoon, Jun-Bo

    2017-12-01

    This paper proposes a device level solution to achieve linear frequency tuning with respect to a tuning voltage ( V tune ) sweep in an inductor ( L)-capacitor ( C) resonant system. Since the linearity of the resonant frequency vs. tuning voltage ( f- V) relationship in an LC-resonant system is closely related to the C- V response characteristic of the varactor, we propose a C- V response tunable varactor to realize the linear frequency tuning. The proposed varactor was fabricated using microelectromechanical system (MEMS) surface micromachining. The fabricated MEMS varactor has the ability to dynamically change the C- V response characteristic according to a curve control voltage ( V curve- control ). When V curve- control was increased from zero to 9 V, the C- V response curve was changed from a linear to a concave form (i.e., the capacitance decreased quickly in the low tuning voltage region and slowly in the high tuning voltage region). This change in the C- V response characteristic resulted in a change in the f- V relationship, and we successfully demonstrated almost perfectly linear frequency tuning in the LC-resonant system, with a linearity factor of 99.95%.

  14. Computer-Aided Transformation of PDE Models: Languages, Representations, and a Calculus of Operations

    DTIC Science & Technology

    2016-01-05

    discretizations . We maintain that what is clear at the mathematical level should be equally clear in computation. In this small STIR project, we separate the...concerns of describing and discretizing such models by defining an input language representing PDE, including steady-state and tran- sient, linear and...solvers, such as [8, 9], focused on the solvers themselves and particular families of discretizations (e. g. finite elements), and now it is natural to

  15. Non-linear vibrations of sandwich viscoelastic shells

    NASA Astrophysics Data System (ADS)

    Benchouaf, Lahcen; Boutyour, El Hassan; Daya, El Mostafa; Potier-Ferry, Michel

    2018-04-01

    This paper deals with the non-linear vibration of sandwich viscoelastic shell structures. Coupling a harmonic balance method with the Galerkin's procedure, one obtains an amplitude equation depending on two complex coefficients. The latter are determined by solving a classical eigenvalue problem and two linear ones. This permits to get the non-linear frequency and the non-linear loss factor as functions of the displacement amplitude. To validate our approach, these relationships are illustrated in the case of a circular sandwich ring.

  16. Linear network representation of multistate models of transport.

    PubMed Central

    Sandblom, J; Ring, A; Eisenman, G

    1982-01-01

    By introducing external driving forces in rate-theory models of transport we show how the Eyring rate equations can be transformed into Ohm's law with potentials that obey Kirchhoff's second law. From such a formalism the state diagram of a multioccupancy multicomponent system can be directly converted into linear network with resistors connecting nodal (branch) points and with capacitances connecting each nodal point with a reference point. The external forces appear as emf or current generators in the network. This theory allows the algebraic methods of linear network theory to be used in solving the flux equations for multistate models and is particularly useful for making proper simplifying approximation in models of complex membrane structure. Some general properties of linear network representation are also deduced. It is shown, for instance, that Maxwell's reciprocity relationships of linear networks lead directly to Onsager's relationships in the near equilibrium region. Finally, as an example of the procedure, the equivalent circuit method is used to solve the equations for a few transport models. PMID:7093425

  17. Water pollution and income relationships: A seemingly unrelated partially linear analysis

    NASA Astrophysics Data System (ADS)

    Pandit, Mahesh; Paudel, Krishna P.

    2016-10-01

    We used a seemingly unrelated partially linear model (SUPLM) to address a potential correlation between pollutants (nitrogen, phosphorous, dissolved oxygen and mercury) in an environmental Kuznets curve study. Simulation studies show that the SUPLM performs well to address potential correlation among pollutants. We find that the relationship between income and pollution follows an inverted U-shaped curve for nitrogen and dissolved oxygen and a cubic shaped curve for mercury. Model specification tests suggest that a SUPLM is better specified compared to a parametric model to study the income-pollution relationship. Results suggest a need to continually assess policy effectiveness of pollution reduction as income increases.

  18. Managing Your Administrator.

    ERIC Educational Resources Information Center

    Von Bergen, C. W.; Soper, Barlow; Licata, Jane W.

    2002-01-01

    Explains why effective teachers need relationships of mutual respect and understanding with their supervisors. Makes suggestions for building relationships: understand administrators' objectives, pressures, strengths, weaknesses, and preferred styles; communicate needs clearly; and keep administrators informed. Describes incompetent types of…

  19. Loss of life expectancy derived from a standardized mortality ratio in Denmark, Finland, Norway and Sweden.

    PubMed

    Skriver, Mette Vinther; Væth, Michael; Støvring, Henrik

    2018-01-01

    The standardized mortality ratio (SMR) is a widely used measure. A recent methodological study provided an accurate approximate relationship between an SMR and difference in lifetime expectancies. This study examines the usefulness of the theoretical relationship, when comparing historic mortality data in four Scandinavian populations. For Denmark, Finland, Norway and Sweden, data on mortality every fifth year in the period 1950 to 2010 were obtained. Using 1980 as the reference year, SMRs and difference in life expectancy were calculated. The assumptions behind the theoretical relationship were examined graphically. The theoretical relationship predicts a linear association with a slope, [Formula: see text], between log(SMR) and difference in life expectancies, and the theoretical prediction and calculated differences in lifetime expectancies were compared. We examined the linear association both for life expectancy at birth and at age 30. All analyses were done for females, males and the total population. The approximate relationship provided accurate predictions of actual differences in lifetime expectancies. The accuracy of the predictions was better when age was restricted to above 30, and improved if the changes in mortality rate were close to a proportional change. Slopes of the linear relationship were generally around 9 for females and 10 for males. The theoretically derived relationship between SMR and difference in life expectancies provides an accurate prediction for comparing populations with approximately proportional differences in mortality, and was relatively robust. The relationship may provide a useful prediction of differences in lifetime expectancies, which can be more readily communicated and understood.

  20. Examining the influence of link function misspecification in conventional regression models for developing crash modification factors.

    PubMed

    Wu, Lingtao; Lord, Dominique

    2017-05-01

    This study further examined the use of regression models for developing crash modification factors (CMFs), specifically focusing on the misspecification in the link function. The primary objectives were to validate the accuracy of CMFs derived from the commonly used regression models (i.e., generalized linear models or GLMs with additive linear link functions) when some of the variables have nonlinear relationships and quantify the amount of bias as a function of the nonlinearity. Using the concept of artificial realistic data, various linear and nonlinear crash modification functions (CM-Functions) were assumed for three variables. Crash counts were randomly generated based on these CM-Functions. CMFs were then derived from regression models for three different scenarios. The results were compared with the assumed true values. The main findings are summarized as follows: (1) when some variables have nonlinear relationships with crash risk, the CMFs for these variables derived from the commonly used GLMs are all biased, especially around areas away from the baseline conditions (e.g., boundary areas); (2) with the increase in nonlinearity (i.e., nonlinear relationship becomes stronger), the bias becomes more significant; (3) the quality of CMFs for other variables having linear relationships can be influenced when mixed with those having nonlinear relationships, but the accuracy may still be acceptable; and (4) the misuse of the link function for one or more variables can also lead to biased estimates for other parameters. This study raised the importance of the link function when using regression models for developing CMFs. Copyright © 2017 Elsevier Ltd. All rights reserved.

  1. Age and neurodegeneration imaging biomarkers in persons with Alzheimer disease dementia

    PubMed Central

    Jack, Clifford R.; Wiste, Heather J.; Weigand, Stephen D.; Vemuri, Prashanthi; Lowe, Val J.; Kantarci, Kejal; Gunter, Jeffrey L.; Senjem, Matthew L.; Mielke, Michelle M.; Machulda, Mary M.; Roberts, Rosebud O.; Boeve, Bradley F.; Jones, David T.; Petersen, Ronald C.

    2016-01-01

    Objective: To examine neurodegenerative imaging biomarkers in Alzheimer disease (AD) dementia from middle to old age. Methods: Persons with AD dementia and elevated brain β-amyloid with Pittsburgh compound B (PiB)-PET imaging underwent [18F]-fluorodeoxyglucose (FDG)-PET and structural MRI. We evaluated 3 AD-related neurodegeneration biomarkers: hippocampal volume adjusted for total intracranial volume (HVa), FDG standardized uptake value ratio (SUVR) in regions of interest linked to AD, and cortical thickness in AD-related regions of interest. We examined associations of each biomarker with age and evaluated age effects on cutpoints defined by the 90th percentile in AD dementia. We assembled an age-, sex-, and intracranial volume-matched group of 194 similarly imaged clinically normal (CN) persons. Results: The 97 participants with AD dementia (aged 49–93 years) had PiB SUVR ≥1.8. A nonlinear (inverted-U) relationship between FDG SUVR and age was seen in the AD group but an inverse linear relationship with age was seen in the CN group. Cortical thickness had an inverse linear relationship with age in AD but a nonlinear (flat, then inverse linear) relationship in the CN group. HVa showed an inverse linear relationship with age in both AD and CN groups. Age effects on 90th percentile cutpoints were small for FDG SUVR and cortical thickness, but larger for HVa. Conclusions: In persons with AD dementia with elevated PiB SUVR, values of each neurodegeneration biomarker were associated with age. Cortical thickness had the smallest differences in 90th percentile cutpoints from middle to old age, and HVa the largest differences. PMID:27421543

  2. Age and neurodegeneration imaging biomarkers in persons with Alzheimer disease dementia.

    PubMed

    Knopman, David S; Jack, Clifford R; Wiste, Heather J; Weigand, Stephen D; Vemuri, Prashanthi; Lowe, Val J; Kantarci, Kejal; Gunter, Jeffrey L; Senjem, Matthew L; Mielke, Michelle M; Machulda, Mary M; Roberts, Rosebud O; Boeve, Bradley F; Jones, David T; Petersen, Ronald C

    2016-08-16

    To examine neurodegenerative imaging biomarkers in Alzheimer disease (AD) dementia from middle to old age. Persons with AD dementia and elevated brain β-amyloid with Pittsburgh compound B (PiB)-PET imaging underwent [(18)F]-fluorodeoxyglucose (FDG)-PET and structural MRI. We evaluated 3 AD-related neurodegeneration biomarkers: hippocampal volume adjusted for total intracranial volume (HVa), FDG standardized uptake value ratio (SUVR) in regions of interest linked to AD, and cortical thickness in AD-related regions of interest. We examined associations of each biomarker with age and evaluated age effects on cutpoints defined by the 90th percentile in AD dementia. We assembled an age-, sex-, and intracranial volume-matched group of 194 similarly imaged clinically normal (CN) persons. The 97 participants with AD dementia (aged 49-93 years) had PiB SUVR ≥1.8. A nonlinear (inverted-U) relationship between FDG SUVR and age was seen in the AD group but an inverse linear relationship with age was seen in the CN group. Cortical thickness had an inverse linear relationship with age in AD but a nonlinear (flat, then inverse linear) relationship in the CN group. HVa showed an inverse linear relationship with age in both AD and CN groups. Age effects on 90th percentile cutpoints were small for FDG SUVR and cortical thickness, but larger for HVa. In persons with AD dementia with elevated PiB SUVR, values of each neurodegeneration biomarker were associated with age. Cortical thickness had the smallest differences in 90th percentile cutpoints from middle to old age, and HVa the largest differences. © 2016 American Academy of Neurology.

  3. Physical Performance and Serum 25(OH)vitamin D Status in Community Dwelling Old Mobility Limited Adults: A Cross-Sectional Study.

    PubMed

    von Berens, Å; Cederholm, T; Fielding, R A; Gustafsson, T; Kirn, D; Laussen, J; Nydahl, M; Travison, T G; Reid, K; Koochek, A

    2018-01-01

    To examine the potential association between serum 25(OH) vitamin D and the performance on the Short Physical Performance Battery (SPPB) including the sub-components; five repeated chair stands test, 4 meters walk test and balance in older mobility-limited community-dwelling men and women. A cross sectional study was performed in American and Swedish subjects who were examined for potential participation in a combined exercise and nutrition intervention trial. Logistic regression analysis and linear regression analyses were performed to evaluate the association for 25(OH)D with the overall score on the SBBP, chair stand, gait speed and balance. Community-dwelling (mean age 77.6 ± 5.3 years) mobility limited American (n=494) and Swedish (n=116) females (59%) and males. The SPPB (0-12 points) includes chair stand (s), gait speed (m/s) and a balance test. Mobility limitation i.e., SPPB score ≤ 9 was an inclusion criterion. A blood sample was obtained to measure serum 25(OH)vitamin D concentrations. No clear association of 25(OH)D with SPPB scores was detected either when 25(OH)D was assessed as a continuous variable or when categorized according to serum concentrations of <50, 50-75 or <75 nmol/L. However, when analyzing the relationship between 25(OH)D and seconds to perform the chair stands, a significant quadratic relationship was observed. Thus, at serum levels of 25(OH)D above 74 nmol/L, higher concentrations appeared to be advantageous for the chair stand test, whereas for serum levels below 74 nmol/L this association was not observed. This cross- sectional study lacked clear association between serum 25(OH)D and physical performance in mobility limited adults. A potentially interesting observation was that at higher serum levels of 25(OH)D a better performance on the chair stand test was indicated.

  4. Unskilled Writers as Composers.

    ERIC Educational Resources Information Center

    Perl, Sondra

    1979-01-01

    Composition is not a straightforward, linear process; it involves a creative search for meaning that becomes clear only as the writer engages in the composing process. This suggests that teaching not dwell on the correctness of the finished product. (Author/SJL)

  5. Mask patterning process using the negative tone chemically amplified resist TOK OEBR-CAN024

    NASA Astrophysics Data System (ADS)

    Irmscher, Mathias; Beyer, Dirk; Butschke, Joerg; Hudek, Peter; Koepernik, Corinna; Plumhoff, Jason; Rausa, Emmanuel; Sato, Mitsuru; Voehringer, Peter

    2004-08-01

    Optimized process parameters using the TOK OEBR-CAN024 resist for high chrome load patterning have been determined. A tight linearity tolerance for opaque and clear features, independent on the local pattern density, was the goal of our process integration work. For this purpose we evaluated a new correction method taking into account electron scattering and process influences. The method is based on matching of measured pattern geometry by iterative back-simulation using multiple Gauss and/or exponential functions. The obtained control function acts as input for the proximity correction software PROXECCO. Approaches with different pattern oversize and two Cr thicknesses were accomplished and the results have been reported. Isolated opaque and clear lines could be realized in a very tight linearity range. The increasing line width of small dense lines, induced by the etching process, could be corrected only partially.

  6. Aspects of decision support in water management--example Berlin and Potsdam (Germany) I--spatially differentiated evaluation.

    PubMed

    Simon, Ute; Brüggemann, Rainer; Pudenz, Stefan

    2004-04-01

    Decisions about sustainable development demand spatially differentiated evaluations. As an example, we demonstrate the evaluation of water management strategies in the cities of Berlin and Potsdam (Germany) with respect to their ecological effects in 14 sections of the surface water system. Two decision support systems were compared, namely PROMETHEE, which is designed to obtain a clear decision (linear ranking), and Hasse Diagram Technique (HDT), normally providing more than one favourable solution (partial order). By PROMETHEE, the spatial differentiation had unwanted effects on the result, negating the stakeholders determined weighting of indicators. Therefore, the stakeholder can barely benefit from the convenience of obtaining a clear decision (linear ranking). In contrast, the result obtained by HDT was not influenced by spatial differentiation. Furthermore, HDT provided helpful tools to analyse the evaluation result, such as the concept of antagonistic indicators to discover conflicts in the evaluation process.

  7. Relationship between forest clearing and biophysical factors in tropical environments: Implications for the design of a forest change monitoring approach. [Costa Rica

    NASA Technical Reports Server (NTRS)

    Sader, S. A.; Joyce, A. T.

    1984-01-01

    The relationship between forest clearing, biophysical factors (e.g, ecological zones, slope gradient, soils), and transportation network in Costa Rica was analyzed. The location of forested areas at four reference datas (1940, 1950, 1961, and 1977) as derived from aerial photography and LANDSAT MSS data was digitilized and entered into a geographically-referenced data base. Ecological zones as protrayed by the Holdridge Life Zone Ecology System, and the location of roads and railways were also digitized from maps of the entire country as input to the data base. Information on slope gradient and soils was digitized from maps of a 21,000 square kilometer area. The total area of forest cleared over four decades are related to biophysical factors was analyzed within the data base and deforestation rates and trends were tabulated. The relatiohship between forest clearing and ecological zone and the influence of topography, sils, and transportation network are presented and discussed.

  8. Reconciling inconsistencies in precipitation-productivity relationships: implications for climate change.

    PubMed

    Knapp, Alan K; Ciais, Philippe; Smith, Melinda D

    2017-04-01

    Contents 41 I. 41 II. 42 III. 43 IV. 44 V. 45 Acknowledgements 46 References 46 SUMMARY: Precipitation (PPT) is a primary climatic determinant of plant growth and aboveground net primary production (ANPP) over much of the globe. Thus, PPT-ANPP relationships are important both ecologically and to land-atmosphere models that couple terrestrial vegetation to the global carbon cycle. Empirical PPT-ANPP relationships derived from long-term site-based data are almost always portrayed as linear, but recent evidence has accumulated that is inconsistent with an underlying linear relationship. We review, and then reconcile, these inconsistencies with a nonlinear model that incorporates observed asymmetries in PPT-ANPP relationships. Although data are currently lacking for parameterization, this new model highlights research needs that, when met, will improve our understanding of carbon cycle dynamics, as well as forecasts of ecosystem responses to climate change. © 2016 The Authors. New Phytologist © 2016 New Phytologist Trust.

  9. Optical and biometric relationships of the isolated pig crystalline lens.

    PubMed

    Vilupuru, A S; Glasser, A

    2001-07-01

    To investigate the interrelationships between optical and biometric properties of the porcine crystalline lens, to compare these findings with similar relationships found for the human lens and to attempt to fit this data to a geometric model of the optical and biometric properties of the pig lens. Weight, focal length, spherical aberration, surface curvatures, thickness and diameters of 20 isolated pig lenses were measured and equivalent refractive index was calculated. These parameters were compared and used to geometrically model the pig lens. Linear relationships were identified between many of the lens biometric and optical properties. The existence of these relationships allowed a simple geometrical model of the pig lens to be calculated which offers predictions of the optical properties. The linear relationships found and the agreement observed between measured and modeled results suggest that the pig lens confirms to a predictable, preset developmental pattern and that the optical and biometric properties are predictably interrelated.

  10. Revisiting the investor sentiment-stock returns relationship: A multi-scale perspective using wavelets

    NASA Astrophysics Data System (ADS)

    Lao, Jiashun; Nie, He; Jiang, Yonghong

    2018-06-01

    This paper employs SBW proposed by Baker and Wurgler (2006) to investigate the nonlinear asymmetric Granger causality between investor sentiment and stock returns for US economy while considering different time-scales. The wavelet method is utilized to decompose time series of investor sentiment and stock returns at different time-scales to focus on the local analysis of different time horizons of investors. The linear and nonlinear asymmetric Granger methods are employed to examine the Granger causal relationship on similar time-scales. We find evidence of strong bilateral linear and nonlinear asymmetric Granger causality between longer-term investor sentiment and stock returns. Furthermore, we observe the positive nonlinear causal relationship from stock returns to investor sentiment and the negative nonlinear causal relationship from investor sentiment to stock returns.

  11. Inverter ratio failure detector

    NASA Technical Reports Server (NTRS)

    Wagner, A. P.; Ebersole, T. J.; Andrews, R. E. (Inventor)

    1974-01-01

    A failure detector which detects the failure of a dc to ac inverter is disclosed. The inverter under failureless conditions is characterized by a known linear relationship of its input and output voltages and by a known linear relationship of its input and output currents. The detector includes circuitry which is responsive to the detector's input and output voltages and which provides a failure-indicating signal only when the monitored output voltage is less by a selected factor, than the expected output voltage for the monitored input voltage, based on the known voltages' relationship. Similarly, the detector includes circuitry which is responsive to the input and output currents and provides a failure-indicating signal only when the input current exceeds by a selected factor the expected input current for the monitored output current based on the known currents' relationship.

  12. The nonlinear relationship between cerebrospinal fluid Aβ42 and tau in preclinical Alzheimer's disease.

    PubMed

    de Leon, Mony J; Pirraglia, Elizabeth; Osorio, Ricardo S; Glodzik, Lidia; Saint-Louis, Les; Kim, Hee-Jin; Fortea, Juan; Fossati, Silvia; Laska, Eugene; Siegel, Carole; Butler, Tracy; Li, Yi; Rusinek, Henry; Zetterberg, Henrik; Blennow, Kaj

    2018-01-01

    Cerebrospinal fluid (CSF) studies consistently show that CSF levels of amyloid-beta 1-42 (Aβ42) are reduced and tau levels increased prior to the onset of cognitive decline related to Alzheimer's disease (AD). However, the preclinical prediction accuracy for low CSF Aβ42 levels, a surrogate for brain Aβ42 deposits, is not high. Moreover, the pathology data suggests a course initiated by tauopathy contradicting the contemporary clinical view of an Aβ initiated cascade. CSF Aβ42 and tau data from 3 normal aging cohorts (45-90 years) were combined to test both cross-sectional (n = 766) and longitudinal (n = 651) hypotheses: 1) that the relationship between CSF levels of Aβ42 and tau are not linear over the adult life-span; and 2) that non-linear models improve the prediction of cognitive decline. Supporting the hypotheses, the results showed that a u-shaped quadratic fit (Aβ2) best describes the relationship for CSF Aβ42 with CSF tau levels. Furthermore we found that the relationship between Aβ42 and tau changes with age-between 45 and 70 years there is a positive linear association, whereas between 71 and 90 years there is a negative linear association between Aβ42 and tau. The quadratic effect appears to be unique to Aβ42, as Aβ38 and Aβ40 showed only positive linear relationships with age and CSF tau. Importantly, we observed the prediction of cognitive decline was improved by considering both high and low levels of Aβ42. Overall, these data suggest an earlier preclinical stage than currently appreciated, marked by CSF elevations in tau and accompanied by either elevations or reductions in Aβ42. Future studies are needed to examine potential mechanisms such as failing CSF clearance as a common factor elevating CSF Aβxx analyte levels prior to Aβ42 deposition in brain.

  13. The Multiple Correspondence Analysis Method and Brain Functional Connectivity: Its Application to the Study of the Non-linear Relationships of Motor Cortex and Basal Ganglia.

    PubMed

    Rodriguez-Sabate, Clara; Morales, Ingrid; Sanchez, Alberto; Rodriguez, Manuel

    2017-01-01

    The complexity of basal ganglia (BG) interactions is often condensed into simple models mainly based on animal data and that present BG in closed-loop cortico-subcortical circuits of excitatory/inhibitory pathways which analyze the incoming cortical data and return the processed information to the cortex. This study was aimed at identifying functional relationships in the BG motor-loop of 24 healthy-subjects who provided written, informed consent and whose BOLD-activity was recorded by MRI methods. The analysis of the functional interaction between these centers by correlation techniques and multiple linear regression showed non-linear relationships which cannot be suitably addressed with these methods. The multiple correspondence analysis (MCA), an unsupervised multivariable procedure which can identify non-linear interactions, was used to study the functional connectivity of BG when subjects were at rest. Linear methods showed different functional interactions expected according to current BG models. MCA showed additional functional interactions which were not evident when using lineal methods. Seven functional configurations of BG were identified with MCA, two involving the primary motor and somatosensory cortex, one involving the deepest BG (external-internal globus pallidum, subthalamic nucleus and substantia nigral), one with the input-output BG centers (putamen and motor thalamus), two linking the input-output centers with other BG (external pallidum and subthalamic nucleus), and one linking the external pallidum and the substantia nigral. The results provide evidence that the non-linear MCA and linear methods are complementary and should be best used in conjunction to more fully understand the nature of functional connectivity of brain centers.

  14. Map showing the association of linear features with metallic mines and prospects in the Butte 1 degree by 2 degrees Quadrangle, Montana

    USGS Publications Warehouse

    Rowan, L.C.; Trautwein, C.M.; Purdy, T.L.

    1990-01-01

    This study was undertaken as part of the Conterminous U.S. Mineral Assessment Program (CUSMAP). The purpose of the study was to map linear features on Landsat Multispectral Scanner (MSS) images and a proprietary side-looking airborne radar (SLAR) image mosaic and to determine the spatial relationship between these linear features and the locations of metallic mineral occurrE-nces. The results show a close spatial association of linear features with metallic mineral occurrences in parts of the quadrangle, but in other areas the association is less well defined. Linear features are defined as distinct linear and slightly curvilinear elements mappable on MSS and SLAR images. The features generally represent linear segments of streams, ridges, and terminations of topographic features; however, they may also represent tonal patterns that are related to variations in lithology and vegetation. Most linear features in the Butte quadrangle probably represent underlying structural elements, such as fractures (with and without displacement), dikes, and alignment of fold axes. However, in areas underlain by sedimentary rocks, some of the linear features may reflect bedding traces. This report describes the geologic setting of the Butte quadrangle, the procedures used in mapping and analyzing the linear features, and the results of the study. Relationship of these features to placer and non-metal deposits were not analyzed in this study and are not discussed in this report.

  15. Building Relationships, Yielding Results: How Superintendents Can Work with School Boards to Create Productive Teams

    ERIC Educational Resources Information Center

    Hackett, Julie L.

    2015-01-01

    In "Building Relationships, Yielding Results," the seasoned superintendent of an urban school district provides a clear road map for effective collaboration with school boards and the type of relationship-building required to achieve long-term, sustainable reforms. Instead of keeping school board members at arm's length or inundating…

  16. Relationship between Learning Outcomes and Online Accesses

    ERIC Educational Resources Information Center

    Suanpang, Pannee; Petocz, Peter; Reid, Anna

    2004-01-01

    This paper reports on a study carried out in Thailand investigating the relationship between students' use of an e-learning system and their learning outcomes in a course on Business Statistics. The results show a clear relationship between accesses to the e-learning system, as measured by number of "hits", and outcomes, as measured by…

  17. "Embedded" Youth Work: Ethical Questions for Youth Work Professionals

    ERIC Educational Resources Information Center

    Sercombe, Howard

    2007-01-01

    Most professions have wrestled with the problem of dual relationships, and the profession of youth work is no exception. Howard Sercombe holds that in order to understand how dual relationships can be avoided within youth work, it is necessary to be clear about what is involved in professional relationships. Sercombe also outlines policies that…

  18. Quantifying urbanization as a risk factor for noncommunicable disease.

    PubMed

    Allender, Steven; Wickramasinghe, Kremlin; Goldacre, Michael; Matthews, David; Katulanda, Prasad

    2011-10-01

    The aim of this study was to investigate the poorly understood relationship between the process of urbanization and noncommunicable diseases (NCDs) in Sri Lanka using a multicomponent, quantitative measure of urbanicity. NCD prevalence data were taken from the Sri Lankan Diabetes and Cardiovascular Study, comprising a representative sample of people from seven of the nine provinces in Sri Lanka (n = 4,485/5,000; response rate = 89.7%). We constructed a measure of the urban environment for seven areas using a 7-item scale based on data from study clusters to develop an "urbanicity" scale. The items were population size, population density, and access to markets, transportation, communications/media, economic factors, environment/sanitation, health, education, and housing quality. Linear and logistic regression models were constructed to examine the relationship between urbanicity and chronic disease risk factors. Among men, urbanicity was positively associated with physical inactivity (odds ratio [OR] = 3.22; 2.27-4.57), high body mass index (OR = 2.45; 95% CI, 1.88-3.20) and diabetes mellitus (OR = 2.44; 95% CI, 1.66-3.57). Among women, too, urbanicity was positively associated with physical inactivity (OR = 2.29; 95% CI, 1.64-3.21), high body mass index (OR = 2.92; 95% CI, 2.41-3.55), and diabetes mellitus (OR = 2.10; 95% CI, 1.58 - 2.80). There is a clear relationship between urbanicity and common modifiable risk factors for chronic disease in a representative sample of Sri Lankan adults.

  19. A mixed model for the relationship between climate and human cranial form.

    PubMed

    Katz, David C; Grote, Mark N; Weaver, Timothy D

    2016-08-01

    We expand upon a multivariate mixed model from quantitative genetics in order to estimate the magnitude of climate effects in a global sample of recent human crania. In humans, genetic distances are correlated with distances based on cranial form, suggesting that population structure influences both genetic and quantitative trait variation. Studies controlling for this structure have demonstrated significant underlying associations of cranial distances with ecological distances derived from climate variables. However, to assess the biological importance of an ecological predictor, estimates of effect size and uncertainty in the original units of measurement are clearly preferable to significance claims based on units of distance. Unfortunately, the magnitudes of ecological effects are difficult to obtain with distance-based methods, while models that produce estimates of effect size generally do not scale to high-dimensional data like cranial shape and form. Using recent innovations that extend quantitative genetics mixed models to highly multivariate observations, we estimate morphological effects associated with a climate predictor for a subset of the Howells craniometric dataset. Several measurements, particularly those associated with cranial vault breadth, show a substantial linear association with climate, and the multivariate model incorporating a climate predictor is preferred in model comparison. Previous studies demonstrated the existence of a relationship between climate and cranial form. The mixed model quantifies this relationship concretely. Evolutionary questions that require population structure and phylogeny to be disentangled from potential drivers of selection may be particularly well addressed by mixed models. Am J Phys Anthropol 160:593-603, 2016. © 2015 Wiley Periodicals, Inc. © 2015 Wiley Periodicals, Inc.

  20. Periphyton responses to nutrient and atrazine mixtures introduced through agricultural runoff.

    PubMed

    Murdock, Justin N; Shields, F Douglas; Lizotte, Richard E

    2013-03-01

    Agricultural runoff often contains pollutants with antagonistic impacts. The individual influence of nutrients and atrazine on periphyton has been extensively studied, but their impact when introduced together and with multiple agricultural pollutants is less clear. We simulated a field-scale runoff pulse into a riverine wetland that mimicked pollutant composition typical of field runoff of the Mississippi River Alluvial Plain. Periphyton biomass and functional responses were measured for 2 weeks along a 500 m section. Additionally, laboratory chamber assays were used to identify potential periphyton changes due to nutrients, atrazine, and their interactions. Generally, nutrients stimulated, and atrazine reduced chlorophyll a (Chl a) in chambers. In the wetland, nutrient and atrazine relationships with periphyton were weaker, and when found, were often opposite of trends in chambers. Total nitrogen (TN) was inversely related to Chl a, and total phosphorus was inversely related to respiration (R) rates. Atrazine (10-20 μg L(-1) in the wetland) had a positive relationship with ash-free dry mass (AFDM), and weakened the relationship between TN and AFDM. Wetland periphyton biomass was better correlated to total suspended solids than nutrients or atrazine. Periphyton function was resilient as periphyton gross primary production (GPP)/R ratios were not strongly impacted by runoff. However, whole-system GPP and R decreased over the 2-week period, suggesting that although periphyton metabolism recovered quickly, whole-system metabolism took longer to recover. The individual and combined impacts of nutrients and atrazine in complex pollutant mixtures can vary substantially from their influence when introduced separately, and non-linear impacts can occur with distance downstream of the pollutant introduction point.

  1. Quantification of intensive hybrid coastal reclamation for revealing its impacts on macrozoobenthos

    NASA Astrophysics Data System (ADS)

    Yan, Jiaguo; Cui, Baoshan; Zheng, Jingjing; Xie, Tian; Wang, Qing; Li, Shanze

    2015-01-01

    Managing and identifying the sources of anthropogenic stress in coastal wetlands requires an in-depth understanding of relationships between species diversity and human activities. Empirical and experimental studies provide clear evidence that coastal reclamation can have profound impacts on marine organisms, but the focus of such studies is generally on comparative or laboratory research. We developed a compound intensity index (reclamation intensity index, RI) on hybrid coastal reclamation, to quantify the impacts of reclamation on coastal ecosystems. We also made use of mean annual absolute changes to a number of biotic variables (biodiversity, species richness, biomass of total macrozoobenthos, and species richness and biomass of Polychaeta, Mollusca, Crustacea, and Echinodermata) to determine Hedges’d index, which is a measure of the potential effects of coastal reclamation. Our results showed that there was significant difference of coastal reclamation intensity between Yellow Sea, East China Sea and South China Sea, the biological changes in effect sizes of the three regions differed greatly over time. Our modelling analyses showed that hybrid coastal reclamation generally had significant negative impacts on species diversity and biomass of macrozoobenthos. These relationships varied among different taxonomic groups and included both linear and nonlinear relationships. The results indicated that a high-intensity of coastal reclamation contributed to a pronounced decline in species diversity and biomass, while lower-intensity reclamation, or reclamation within certain thresholds, resulted in a small increase in species diversity and biomass. These results have important implications for biodiversity conservation and the ecological restoration of coastal wetlands in face of the intensive reclamation activities.

  2. Quantitative Effects of P Elements on Hybrid Dysgenesis in Drosophila Melanogaster

    PubMed Central

    Rasmusson, K. E.; Simmons, M. J.; Raymond, J. D.; McLarnon, C. F.

    1990-01-01

    Genetic analyses involving chromosomes from seven inbred lines derived from a single M' strain were used to study the quantitative relationships between the incidence and severity of P-M hybrid dysgenesis and the number of genomic P elements. In four separate analyses, the mutability of sn(w), a P element-insertion mutation of the X-linked singed locus, was found to be inversely related to the number of autosomal P elements. Since sn(w) mutability is caused by the action of the P transposase, this finding supports the hypothesis that genomic P elements titrate the transposase present within a cell. Other analyses demonstrated that autosomal transmission ratios were distorted by P element action. In these analyses, the amount of distortion against an autosome increased more or less linearly with the number of P elements carried by the autosome. Additional analyses showed that the magnitude of this distortion was reduced when a second P element-containing autosome was present in the genome. This reduction could adequately be explained by transposase titration; there was no evidence that it was due to repressor molecules binding to P elements and inhibiting their movement. The influence of genomic P elements on the incidence of gonadal dysgenesis was also investigated. Although no simple relationship between the number of P elements and the incidence of the trait could be discerned, it was clear that even a small number of elements could increase the incidence markedly. The failure to find a quantitative relationship between P element number and the incidence of gonadal dysgenesis probably reflects the complex etiology of this trait. PMID:2155853

  3. Constant and seasonal drivers of bird communities in a wind farm: implications for conservation

    PubMed Central

    Skórka, Piotr; Szymański, Paweł; Tobolka, Marcin; Luczak, Andrzej; Tryjanowski, Piotr

    2016-01-01

    Background. One of the most difficult challenges for conservation biology is to reconcile growing human demands for resources with the rising need for protecting nature. Wind farms producing renewable energy have been recognised to be a threat for birds, but clear directives for environmental planning are still missing. Methods. Point counts were performed to study the relationship between eight environmental variables and bird populations in different parts of a year on the largest Polish wind farm between March 2011 and February 2013. Variables potentially related to species richness (Chao 1 estimator) and the abundance of the entire bird community as well as five selected farmland species were analysed with the use of generalized linear mixed models. Results. Some associations between the studied variables and bird populations were season/year specific, while others had a constant direction (positive or negative) across seasons and/or years. The latter were distance to the nearest turbine, field size, number of wind turbines, proximity of settlements and water bodies. Spatial autocorrelation and counting time were significantly correlated with bird population estimates but the directions of these relationships varied among seasons and years. Associations between abundance of individual species and environmental variables were species-specific. Conclusions. The results demonstrated a constant negative relationship between wind turbine proximity and bird numbers. Other environmental variables, such as field size, proximity of settlements and water bodies that also had constant associations with bird populations across seasons may be taken into account when minimizing adverse effects of wind farm development on birds or choosing optimal locations of new turbines. PMID:27547516

  4. Unraveling the relationship between arterial flow and intra-aneurysmal hemodynamics.

    PubMed

    Morales, Hernán G; Bonnefous, Odile

    2015-02-26

    Arterial flow rate affects intra-aneurysmal hemodynamics but it is not clear how their relationship is. This uncertainty hinders the comparison among studies, including clinical evaluations, like a pre- and post-treatment status, since arterial flow rates may differ at each time acquisition. The purposes of this work are as follows: (1) To study how intra-aneurysmal hemodynamics changes within the full physiological range of arterial flow rates. (2) To provide characteristic curves of intra-aneurysmal velocity, wall shear stress (WSS) and pressure as functions of the arterial flow rate. Fifteen image-based aneurysm models were studied using computational fluid dynamics (CFD) simulations. The full range of physiological arterial flow rates reported in the literature was covered by 11 pulsatile simulations. For each aneurysm, the spatiotemporal-averaged blood flow velocity, WSS and pressure were calculated. Spatiotemporal-averaged velocity inside the aneurysm linearly increases as a function of the mean arterial flow (minimum R(2)>0.963). Spatiotemporal-averaged WSS and pressure at the aneurysm wall can be represented by quadratic functions of the arterial flow rate (minimum R(2)>0.996). Quantitative characterizations of spatiotemporal-averaged velocity, WSS and pressure inside cerebral aneurysms can be obtained with respect to the arterial flow rate. These characteristic curves provide more information of the relationship between arterial flow and aneurysm hemodynamics since the full range of arterial flow rates is considered. Having these curves, it is possible to compare experimental studies and clinical evaluations when different flow conditions are used. Copyright © 2015 Elsevier Ltd. All rights reserved.

  5. Constant and seasonal drivers of bird communities in a wind farm: implications for conservation.

    PubMed

    Rosin, Zuzanna M; Skórka, Piotr; Szymański, Paweł; Tobolka, Marcin; Luczak, Andrzej; Tryjanowski, Piotr

    2016-01-01

    Background. One of the most difficult challenges for conservation biology is to reconcile growing human demands for resources with the rising need for protecting nature. Wind farms producing renewable energy have been recognised to be a threat for birds, but clear directives for environmental planning are still missing. Methods. Point counts were performed to study the relationship between eight environmental variables and bird populations in different parts of a year on the largest Polish wind farm between March 2011 and February 2013. Variables potentially related to species richness (Chao 1 estimator) and the abundance of the entire bird community as well as five selected farmland species were analysed with the use of generalized linear mixed models. Results. Some associations between the studied variables and bird populations were season/year specific, while others had a constant direction (positive or negative) across seasons and/or years. The latter were distance to the nearest turbine, field size, number of wind turbines, proximity of settlements and water bodies. Spatial autocorrelation and counting time were significantly correlated with bird population estimates but the directions of these relationships varied among seasons and years. Associations between abundance of individual species and environmental variables were species-specific. Conclusions. The results demonstrated a constant negative relationship between wind turbine proximity and bird numbers. Other environmental variables, such as field size, proximity of settlements and water bodies that also had constant associations with bird populations across seasons may be taken into account when minimizing adverse effects of wind farm development on birds or choosing optimal locations of new turbines.

  6. Information content versus word length in random typing

    NASA Astrophysics Data System (ADS)

    Ferrer-i-Cancho, Ramon; Moscoso del Prado Martín, Fermín

    2011-12-01

    Recently, it has been claimed that a linear relationship between a measure of information content and word length is expected from word length optimization and it has been shown that this linearity is supported by a strong correlation between information content and word length in many languages (Piantadosi et al 2011 Proc. Nat. Acad. Sci. 108 3825). Here, we study in detail some connections between this measure and standard information theory. The relationship between the measure and word length is studied for the popular random typing process where a text is constructed by pressing keys at random from a keyboard containing letters and a space behaving as a word delimiter. Although this random process does not optimize word lengths according to information content, it exhibits a linear relationship between information content and word length. The exact slope and intercept are presented for three major variants of the random typing process. A strong correlation between information content and word length can simply arise from the units making a word (e.g., letters) and not necessarily from the interplay between a word and its context as proposed by Piantadosi and co-workers. In itself, the linear relation does not entail the results of any optimization process.

  7. Performance indicators related to points scoring and winning in international rugby sevens.

    PubMed

    Higham, Dean G; Hopkins, Will G; Pyne, David B; Anson, Judith M

    2014-05-01

    Identification of performance indicators related to scoring points and winning is needed to inform tactical approaches to international rugby sevens competition. The aim of this study was to characterize team performance indicators in international rugby sevens and quantify their relationship with a team's points scored and probability of winning. Performance indicators of each team during 196 matches of the 2011/2012 International Rugby Board Sevens World Series were modeled for their linear relationships with points scored and likelihood of winning within (changes in team values from match to match) and between (differences between team values averaged over all matches) teams. Relationships were evaluated as the change and difference in points and probability of winning associated with a two within- and between-team standard deviations increase in performance indicator values. Inferences about relationships were assessed using a smallest meaningful difference of one point and a 10% probability of a team changing the outcome of a close match. All indicators exhibited high within-team match-to-match variability (intraclass correlation coefficients ranged from 0.00 to 0.23). Excluding indicators representing points-scoring actions or events occurring on average less than once per match, 13 of 17 indicators had substantial clear within-team relationships with points scored and/or likelihood of victory. Relationships between teams were generally similar in magnitude but unclear. Tactics that increase points scoring and likelihood of winning should be based on greater ball possession, fewer rucks, mauls, turnovers, penalties and free kicks, and limited passing. Key pointsSuccessful international rugby sevens teams tend to maintain ball possession; more frequently avoid taking the ball into contact; concede fewer turnovers, penalties and free kicks; retain possession in scrums, rucks and mauls; and limit passing the ball.Selected performance indicators may be used to evaluate team performances and plan more effective tactical approaches to competition.There is greater match-to-match variability in performance indicator values within than between international rugby sevens teams.The priorities for a rugby sevens team's technical and tactical preparation should reflect the magnitudes of the relationships between performance indicators, points scoring and the likelihood of winning.

  8. Weather and children's physical activity; how and why do relationships vary between countries?

    PubMed

    Harrison, Flo; Goodman, Anna; van Sluijs, Esther M F; Andersen, Lars Bo; Cardon, Greet; Davey, Rachel; Janz, Kathleen F; Kriemler, Susi; Molloy, Lynn; Page, Angie S; Pate, Russ; Puder, Jardena J; Sardinha, Luis B; Timperio, Anna; Wedderkopp, Niels; Jones, Andy P

    2017-05-30

    Globally most children do not engage in enough physical activity. Day length and weather conditions have been identified as determinants of physical activity, although how they may be overcome as barriers is not clear. We aim to examine if and how relationships between children's physical activity and weather and day length vary between countries and identify settings in which children were better able to maintain activity levels given the weather conditions they experienced. In this repeated measures study, we used data from 23,451 participants in the International Children's Accelerometry Database (ICAD). Daily accelerometer-measured physical activity (counts per minute; cpm) was matched to local weather conditions and the relationships assessed using multilevel regression models. Multilevel models accounted for clustering of days within occasions within children within study-cities, and allowed us to explore if and how the relationships between weather variables and physical activity differ by setting. Increased precipitation and wind speed were associated with decreased cpm while better visibility and more hours of daylight were associated with increased cpm. Models indicated that increases in these variables resulted in average changes in mean cpm of 7.6/h of day length, -13.2/cm precipitation, 10.3/10 km visibility and -10.3/10kph wind speed (all p < 0.01). Temperature showed a cubic relationship with cpm, although between 0 and 20 degrees C the relationship was broadly linear. Age showed interactions with temperature and precipitation, with the associations larger among younger children. In terms of geographic trends, participants from Northern European countries and Melbourne, Australia were the most active, and also better maintained their activity levels given the weather conditions they experienced compared to those in the US and Western Europe. We found variation in the relationship between weather conditions and physical activity between ICAD studies and settings. Children in Northern Europe and Melbourne, Australia were not only more active on average, but also more active given the weather conditions they experienced. Future work should consider strategies to mitigate the impacts of weather conditions, especially among young children, and interventions involving changes to the physical environment should consider how they will operate in different weather conditions.

  9. Performance Indicators Related to Points Scoring and Winning in International Rugby Sevens

    PubMed Central

    Higham, Dean G.; Hopkins, Will G.; Pyne, David B.; Anson, Judith M.

    2014-01-01

    Identification of performance indicators related to scoring points and winning is needed to inform tactical approaches to international rugby sevens competition. The aim of this study was to characterize team performance indicators in international rugby sevens and quantify their relationship with a team’s points scored and probability of winning. Performance indicators of each team during 196 matches of the 2011/2012 International Rugby Board Sevens World Series were modeled for their linear relationships with points scored and likelihood of winning within (changes in team values from match to match) and between (differences between team values averaged over all matches) teams. Relationships were evaluated as the change and difference in points and probability of winning associated with a two within- and between-team standard deviations increase in performance indicator values. Inferences about relationships were assessed using a smallest meaningful difference of one point and a 10% probability of a team changing the outcome of a close match. All indicators exhibited high within-team match-to-match variability (intraclass correlation coefficients ranged from 0.00 to 0.23). Excluding indicators representing points-scoring actions or events occurring on average less than once per match, 13 of 17 indicators had substantial clear within-team relationships with points scored and/or likelihood of victory. Relationships between teams were generally similar in magnitude but unclear. Tactics that increase points scoring and likelihood of winning should be based on greater ball possession, fewer rucks, mauls, turnovers, penalties and free kicks, and limited passing. Key points Successful international rugby sevens teams tend to maintain ball possession; more frequently avoid taking the ball into contact; concede fewer turnovers, penalties and free kicks; retain possession in scrums, rucks and mauls; and limit passing the ball. Selected performance indicators may be used to evaluate team performances and plan more effective tactical approaches to competition. There is greater match-to-match variability in performance indicator values within than between international rugby sevens teams. The priorities for a rugby sevens team’s technical and tactical preparation should reflect the magnitudes of the relationships between performance indicators, points scoring and the likelihood of winning. PMID:24790490

  10. Multifractal Detrended Cross-correlation Analysis of Market Clearing Price of electricity and SENSEX in India

    NASA Astrophysics Data System (ADS)

    Ghosh, Dipak; Dutta, Srimonti; Chakraborty, Sayantan

    2015-09-01

    This paper reports a study on the cross-correlation between the electric bid price and SENSEX using Multifractal Detrended Cross-correlation Analysis (MF-DXA). MF-DXA is a very rigorous and robust technique for assessment of cross-correction between two non-linear time series. The study reveals power law cross-correlation between Market Clearing Price (MCP) and SENSEX which suggests that a change in the value of one can create a subjective change in the value of the other.

  11. Comparing Different Approaches for Mapping Urban Vegetation Cover from Landsat ETM+ Data: A Case Study on Brussels

    PubMed Central

    Van de Voorde, Tim; Vlaeminck, Jeroen; Canters, Frank

    2008-01-01

    Urban growth and its related environmental problems call for sustainable urban management policies to safeguard the quality of urban environments. Vegetation plays an important part in this as it provides ecological, social, health and economic benefits to a city's inhabitants. Remotely sensed data are of great value to monitor urban green and despite the clear advantages of contemporary high resolution images, the benefits of medium resolution data should not be discarded. The objective of this research was to estimate fractional vegetation cover from a Landsat ETM+ image with sub-pixel classification, and to compare accuracies obtained with multiple stepwise regression analysis, linear spectral unmixing and multi-layer perceptrons (MLP) at the level of meaningful urban spatial entities. Despite the small, but nevertheless statistically significant differences at pixel level between the alternative approaches, the spatial pattern of vegetation cover and estimation errors is clearly distinctive at neighbourhood level. At this spatially aggregated level, a simple regression model appears to attain sufficient accuracy. For mapping at a spatially more detailed level, the MLP seems to be the most appropriate choice. Brightness normalisation only appeared to affect the linear models, especially the linear spectral unmixing. PMID:27879914

  12. Maternal dietary nitrate intake and risk of neural tube defects: A systematic review and dose-response meta-analysis.

    PubMed

    Kakavandi, Nader Rahimi; Hasanvand, Amin; Ghazi-Khansari, Mahmoud; Sezavar, Ahmad Habibian; Nabizadeh, Hassan; Parohan, Mohammad

    2018-05-12

    Despite growing evidence for the potential teratogenicity of nitrate, knowledge about the dose-response relationship of dietary nitrate intake and risk of specific birth defects such as neural tube defects (NTDs) is limited. Therefore, the aim of this meta-analysis was to synthesize the knowledge about the dose-response relation between maternal dietary nitrate intake and the risk of NTDs. We conducted a systematic search in PubMed, ISI Web of Science and Scopus up to February 2018 for observational studies. Risk ratios (RRs) and 95% confidence intervals (95% CI) were calculated using a random-effects model for highest versus lowest intake categories. The linear and non-linear relationships between nitrate intake and risk of NTDs were also investigated. Overall, 5 studies were included in the meta-analyses. No association was observed between nitrate intake and NTDs risk in high versus low intake (RR: 1.33; 95% CI: 0.89-1.99, p = 0.158) and linear dose-response (RR: 1.03; 95% CI: 0.99-1.07, p = 0.141) meta-analysis. However, there were positive relationships between nitrate intake and risk of NTDs in non-linear (p non-linearity <0.05) model. Findings from this dose-response meta-analysis indicate that maternal nitrate intake higher than ∼3 mg/day is positively associated with NTDs risk. Copyright © 2018 Elsevier Ltd. All rights reserved.

  13. My older sibling was drunk - younger siblings' drunkenness in relation to parental monitoring and the parent-adolescent relationship.

    PubMed

    Gossrau-Breen, Diana; Kuntsche, Emmanuel; Gmel, Gerhard

    2010-10-01

    This study explored the links between having older siblings who get drunk, satisfaction with the parent-adolescent relationship, parental monitoring, and adolescents' risky drinking. Regression models were conducted based on a national representative sample of 3725 8th to 10th graders in Switzerland (mean age 15.0, SD = .93) who indicated having older siblings. Results showed that both parental factors and older siblings' drinking behaviour shape younger siblings' frequency of risky drinking. Parental monitoring showed a linear dose-response relationship, and siblings' influence had an additive effect. There was a non-linear interaction effect between parent-adolescent relationship and older sibling's drunkenness. The findings suggest that, apart from avoiding an increasingly unsatisfactory relationship with their children, parental monitoring appears to be important in preventing risky drinking by their younger children, even if the older sibling drinks in such a way. However, a satisfying relationship with parents does not seem to be sufficient to counterbalance older siblings' influence.

  14. Feedback linearization based control of a variable air volume air conditioning system for cooling applications.

    PubMed

    Thosar, Archana; Patra, Amit; Bhattacharyya, Souvik

    2008-07-01

    Design of a nonlinear control system for a Variable Air Volume Air Conditioning (VAVAC) plant through feedback linearization is presented in this article. VAVAC systems attempt to reduce building energy consumption while maintaining the primary role of air conditioning. The temperature of the space is maintained at a constant level by establishing a balance between the cooling load generated in the space and the air supply delivered to meet the load. The dynamic model of a VAVAC plant is derived and formulated as a MIMO bilinear system. Feedback linearization is applied for decoupling and linearization of the nonlinear model. Simulation results for a laboratory scale plant are presented to demonstrate the potential of keeping comfort and maintaining energy optimal performance by this methodology. Results obtained with a conventional PI controller and a feedback linearizing controller are compared and the superiority of the proposed approach is clearly established.

  15. Centenarian Rates and Life Expectancy Related to the Death Rates of Multiple Sclerosis, Asthma, and Rheumatoid Arthritis and the Incidence of Type 1 Diabetes in Children.

    PubMed

    Lens-Pechakova, Lilia S

    2016-02-01

    The autoimmune diseases are among the 10 leading causes of death for women and the number two cause of chronic illness in America as well as a predisposing factor for cardiovascular diseases and cancer. Patients of some autoimmune diseases have shown a shorter life span and are a model of accelerated immunosenescence. Conversely, centenarians are used as a model of successful aging and have shown several immune parameters that are better preserved and lower levels of autoantibodies. The study reported here focused on clarifying the connection between longevity and some autoimmune and allergic diseases in 29 developed Organisation for Economic Co-operation and Development (OECD) countries, because multidisciplinary analyses of the accelerated or delayed aging data could show a distinct relationship pattern, help to identify common factors, and determine new important factors that contribute to longevity and healthy aging. The relationships between the mortality rates data of multiple sclerosis (MS), rheumatoid arthritis (RA), asthma, the incidence of type 1 diabetes (T1D) from one side and centenarian rates (two sets) as well as life expectancy data from the other side were assessed using regression models and Pearson correlation coefficients. The data obtained correspond to an inverse linear correlation with different degrees of linearity. This is the first observation of a clear tendency of diminishing centenarian rates or life expectancy in countries having higher death rates of asthma, MS, and RA and a higher incidence of T1D in children. The conclusion is that most probably there are common mechanistic pathways and factors affecting the above diseases and at the same time but in the opposite direction the processes of longevity. Further study, comparing genetic data, mechanistic pathways, and other factors connected to autoimmune diseases with those of longevity could clarify the processes involved, so as to promote longevity and limit the expansion of those diseases in the younger and older population.

  16. The association between socioeconomic deprivation and secondary school students' health: findings from a latent class analysis of a national adolescent health survey.

    PubMed

    Denny, Simon; Lewycka, Sonia; Utter, Jennifer; Fleming, Theresa; Peiris-John, Roshini; Sheridan, Janie; Rossen, Fiona; Wynd, Donna; Teevale, Tasileta; Bullen, Pat; Clark, Terryann

    2016-07-16

    The aims of this study were to examine indicators of socioeconomic deprivation among secondary school students and to determine associations between household poverty, neighbourhood deprivation and health indicators. Data were from a nationally representative sample of 8500 secondary school students in New Zealand who participated in a health survey in 2012. Latent class analyses were used to group students by household poverty based on nine indicators of household socioeconomic deprivation: no car; no phone; no computer; their parent/s worry about not having enough money for food; more than two people sharing a bedroom; no holidays with their families; moving home more than twice that year; garages or living rooms used as bedrooms; and, no parent at home with employment. Multilevel generalized linear models were used to estimate the cross-level interaction between household poverty and neighbourhood deprivation with depressive symptoms, cigarette smoking and overweight/ obesity. Three groups of students were identified: 80 % of students had low levels of household poverty across all indicators; 15 % experienced moderate poverty; and 5 % experienced high levels of poverty. Depressive symptoms and cigarette smoking were 2-3 times higher in the poverty groups compared to student's not experiencing poverty. There were also higher rates of overweight/ obesity among students in the poverty groups compared to students not experiencing poverty, but once covariates were accounted for the relationship was less clear. Of note, students experiencing poverty and living in affluent neighbourhoods reported higher levels of depressive symptoms and higher rates of cigarette smoking than students experiencing poverty and living in low socioeconomic neighbourhoods. This cross-level interaction was not seen for overweight/ obesity. Measures of household socioeconomic deprivation among young people should not be combined with neighbourhood measures of socioeconomic deprivation due to non-linear relationships with health and behaviour indicators. Policies are needed that address household poverty alongside efforts to reduce socioeconomic inequalities in neighbourhoods.

  17. Enlarged perivascular spaces and cognitive impairment after stroke and transient ischemic attack.

    PubMed

    Arba, Francesco; Quinn, Terence J; Hankey, Graeme J; Lees, Kennedy R; Wardlaw, Joanna M; Ali, Myzoon; Inzitari, Domenico

    2018-01-01

    Background Previous studies suggested that enlarged perivascular spaces are neuroimaging markers of cerebral small vessel disease. However, it is not clear whether enlarged perivascular spaces are associated with cognitive impairment. We aimed to determine the cross-sectional relationship between enlarged perivascular spaces and small vessel disease, and to investigate the relationship between enlarged perivascular spaces and subsequent cognitive impairment in patients with recent cerebral ischemic event. Methods Anonymized data were accessed from the virtual international stroke trial archive. We rated number of lacunes, white matter hyperintensities, brain atrophy, and enlarged perivascular spaces with validated scales on magnetic resonance brain images after the index stroke. We defined cognitive impairment as a mini mental state examination score of ≤26, recorded at one year post stroke. We examined the associations between enlarged perivascular spaces and clinical and imaging markers of small vessel disease at presentation and clinical evidence of cognitive impairment at one year using linear and logistic regression models. Results We analyzed data on 430 patients with mean (±SD) age 64.7 (±12.7) years, 276 (64%) males. In linear regression analysis, age (β = 0.24; p < 0.001), hypertension (β = 0.09; p = 0.025), and deep white matter hyperintensities (β = 0.31; p < 0.001) were associated with enlarged perivascular spaces. In logistic regression analysis, basal ganglia enlarged perivascular spaces were independently associated with cognitive impairment at one year after adjusting for clinical confounders (OR = 1.72, 95% CI = 1.22-2.42) and for clinical and imaging confounders (OR = 1.54; 95% CI = 1.03-2.31). Conclusions Our data show that in patients with ischemic cerebral events, enlarged perivascular spaces are cross-sectionally associated with age, hypertension, and white matter hyperintensities and suggest that enlarged perivascular spaces in the basal ganglia are associated with cognitive impairment after one year.

  18. Further evidence for CCN aerosol concentrations determining the height of warm rain and ice initiation in convective clouds over the Amazon basin

    NASA Astrophysics Data System (ADS)

    Campos Braga, Ramon; Rosenfeld, Daniel; Weigel, Ralf; Jurkat, Tina; Andreae, Meinrat O.; Wendisch, Manfred; Pöschl, Ulrich; Voigt, Christiane; Mahnke, Christoph; Borrmann, Stephan; Albrecht, Rachel I.; Molleker, Sergej; Vila, Daniel A.; Machado, Luiz A. T.; Grulich, Lucas

    2017-12-01

    We have investigated how aerosols affect the height above cloud base of rain and ice hydrometeor initiation and the subsequent vertical evolution of cloud droplet size and number concentrations in growing convective cumulus. For this purpose we used in situ data of hydrometeor size distributions measured with instruments mounted on HALO aircraft during the ACRIDICON-CHUVA campaign over the Amazon during September 2014. The results show that the height of rain initiation by collision and coalescence processes (Dr, in units of meters above cloud base) is linearly correlated with the number concentration of droplets (Nd in cm-3) nucleated at cloud base (Dr ≈ 5 ṡ Nd). Additional cloud processes associated with Dr, such as GCCN, cloud, and mixing with ambient air and other processes, produce deviations of ˜ 21 % in the linear relationship, but it does not mask the clear relationship between Dr and Nd, which was also found at different regions around the globe (e.g., Israel and India). When Nd exceeded values of about 1000 cm-3, Dr became greater than 5000 m, and the first observed precipitation particles were ice hydrometeors. Therefore, no liquid water raindrops were observed within growing convective cumulus during polluted conditions. Furthermore, the formation of ice particles also took place at higher altitudes in the clouds in polluted conditions because the resulting smaller cloud droplets froze at colder temperatures compared to the larger drops in the unpolluted cases. The measured vertical profiles of droplet effective radius (re) were close to those estimated by assuming adiabatic conditions (rea), supporting the hypothesis that the entrainment and mixing of air into convective clouds is nearly inhomogeneous. Additional CCN activation on aerosol particles from biomass burning and air pollution reduced re below rea, which further inhibited the formation of raindrops and ice particles and resulted in even higher altitudes for rain and ice initiation.

  19. Technical Note: Statistical dependences between channels in radiochromic film readings. Implications in multichannel dosimetry.

    PubMed

    González-López, Antonio; Vera-Sánchez, Juan Antonio; Ruiz-Morales, Carmen

    2016-05-01

    This note studies the statistical relationships between color channels in radiochromic film readings with flatbed scanners. The same relationships are studied for noise. Finally, their implications for multichannel film dosimetry are discussed. Radiochromic films exposed to wedged fields of 6 MV energy were read in a flatbed scanner. The joint histograms of pairs of color channels were used to obtain the joint and conditional probability density functions between channels. Then, the conditional expectations and variances of one channel given another channel were obtained. Noise was extracted from film readings by means of a multiresolution analysis. Two different dose ranges were analyzed, the first one ranging from 112 to 473 cGy and the second one from 52 to 1290 cGy. For the smallest dose range, the conditional expectations of one channel given another channel can be approximated by linear functions, while the conditional variances are fairly constant. The slopes of the linear relationships between channels can be used to simplify the expression that estimates the dose by means of the multichannel method. The slopes of the linear relationships between each channel and the red one can also be interpreted as weights in the final contribution to dose estimation. However, for the largest dose range, the conditional expectations of one channel given another channel are no longer linear functions. Finally, noises in different channels were found to correlate weakly. Signals present in different channels of radiochromic film readings show a strong statistical dependence. By contrast, noise correlates weakly between channels. For the smallest dose range analyzed, the linear behavior between the conditional expectation of one channel given another channel can be used to simplify calculations in multichannel film dosimetry.

  20. Describing three-class task performance: three-class linear discriminant analysis and three-class ROC analysis

    NASA Astrophysics Data System (ADS)

    He, Xin; Frey, Eric C.

    2007-03-01

    Binary ROC analysis has solid decision-theoretic foundations and a close relationship to linear discriminant analysis (LDA). In particular, for the case of Gaussian equal covariance input data, the area under the ROC curve (AUC) value has a direct relationship to the Hotelling trace. Many attempts have been made to extend binary classification methods to multi-class. For example, Fukunaga extended binary LDA to obtain multi-class LDA, which uses the multi-class Hotelling trace as a figure-of-merit, and we have previously developed a three-class ROC analysis method. This work explores the relationship between conventional multi-class LDA and three-class ROC analysis. First, we developed a linear observer, the three-class Hotelling observer (3-HO). For Gaussian equal covariance data, the 3- HO provides equivalent performance to the three-class ideal observer and, under less strict conditions, maximizes the signal to noise ratio for classification of all pairs of the three classes simultaneously. The 3-HO templates are not the eigenvectors obtained from multi-class LDA. Second, we show that the three-class Hotelling trace, which is the figureof- merit in the conventional three-class extension of LDA, has significant limitations. Third, we demonstrate that, under certain conditions, there is a linear relationship between the eigenvectors obtained from multi-class LDA and 3-HO templates. We conclude that the 3-HO based on decision theory has advantages both in its decision theoretic background and in the usefulness of its figure-of-merit. Additionally, there exists the possibility of interpreting the two linear features extracted by the conventional extension of LDA from a decision theoretic point of view.

  1. Technical Note: Statistical dependences between channels in radiochromic film readings. Implications in multichannel dosimetry

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    González-López, Antonio, E-mail: antonio.gonzalez7@carm.es; Vera-Sánchez, Juan Antonio; Ruiz-Morales, Carmen

    Purpose: This note studies the statistical relationships between color channels in radiochromic film readings with flatbed scanners. The same relationships are studied for noise. Finally, their implications for multichannel film dosimetry are discussed. Methods: Radiochromic films exposed to wedged fields of 6 MV energy were read in a flatbed scanner. The joint histograms of pairs of color channels were used to obtain the joint and conditional probability density functions between channels. Then, the conditional expectations and variances of one channel given another channel were obtained. Noise was extracted from film readings by means of a multiresolution analysis. Two different dosemore » ranges were analyzed, the first one ranging from 112 to 473 cGy and the second one from 52 to 1290 cGy. Results: For the smallest dose range, the conditional expectations of one channel given another channel can be approximated by linear functions, while the conditional variances are fairly constant. The slopes of the linear relationships between channels can be used to simplify the expression that estimates the dose by means of the multichannel method. The slopes of the linear relationships between each channel and the red one can also be interpreted as weights in the final contribution to dose estimation. However, for the largest dose range, the conditional expectations of one channel given another channel are no longer linear functions. Finally, noises in different channels were found to correlate weakly. Conclusions: Signals present in different channels of radiochromic film readings show a strong statistical dependence. By contrast, noise correlates weakly between channels. For the smallest dose range analyzed, the linear behavior between the conditional expectation of one channel given another channel can be used to simplify calculations in multichannel film dosimetry.« less

  2. Risk models of dating aggression across different adolescent relationships: a developmental psychopathology approach.

    PubMed

    Williams, Tricia S; Connolly, Jennifer; Pepler, Debra; Craig, Wendy; Laporte, Lise

    2008-08-01

    The present study examined physical dating aggression in different adolescent relationships and assessed linear, threshold, and moderator risk models for recurrent aggressive relationships. The 621 participants (59% girls, 41% boys) were drawn from a 1-year longitudinal survey of Canadian high school youths ranging from Grade 9 through Grade 12. Approximately 13% of participants reported recurrent dating aggression across 2 different relationships. Using peer and dyadic risk factors from Time 1 of the study, the authors confirmed a linear risk model, such that adolescents in 2 different violent relationships had significantly more contextual risk factors than did adolescents in 1 or no violent relationship. Further, structural equation modeling assessing moderation of contextual risk factors indicated that, for adolescents with high acceptance of dating aggression, peer aggression and delinquency significantly predicted recurrent aggression in a new relationship. In comparison, for adolescents with low acceptance of dating aggression, negative relationship characteristics significantly predicted recurrent aggression. Acceptance did not moderate concurrent associations between risk factors and aggression in 1 relationship. Results support a developmental psychopathological approach to the understanding of recurrent aggression and its associated risk factors. Copyright 2008 APA, all rights reserved.

  3. A Fiber Bragg Grating Sensor Interrogation System Based on a Linearly Wavelength-Swept Thermo-Optic Laser Chip

    PubMed Central

    Lee, Hyung-Seok; Lee, Hwi Don; Kim, Hyo Jin; Cho, Jae Du; Jeong, Myung Yung; Kim, Chang-Seok

    2014-01-01

    A linearized wavelength-swept thermo-optic laser chip was applied to demonstrate a fiber Bragg grating (FBG) sensor interrogation system. A broad tuning range of 11.8 nm was periodically obtained from the laser chip for a sweep rate of 16 Hz. To measure the linear time response of the reflection signal from the FBG sensor, a programmed driving signal was directly applied to the wavelength-swept laser chip. The linear wavelength response of the applied strain was clearly extracted with an R-squared value of 0.99994. To test the feasibility of the system for dynamic measurements, the dynamic strain was successfully interrogated with a repetition rate of 0.2 Hz by using this FBG sensor interrogation system. PMID:25177803

  4. Magnetotransport of proton-irradiated BaFe 2As 2 and BaFe 1.985Co 0.015As 2 single crystals

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Moseley, D. A.; Yates, K. A.; Peng, N.

    2015-02-17

    In this paper, we study the magnetotransport properties of the ferropnictide crystals BaFe 2As 2 and BaFe 1.985Co 0.015As 2. These materials exhibit a high field linear magnetoresistance that has been attributed to the quantum linear magnetoresistance model. In this model, the linear magnetoresistance is dependent on the concentration of scattering centers in the material. By using proton-beam irradiation to change the defect scattering density, we find that the dependence of the magnitude of the linear magnetoresistance on scattering quite clearly contravenes this prediction. Finally, a number of other scaling trends in the magnetoresistance and high field Hall data aremore » observed and discussed.« less

  5. The Relationship between Teachers' and Principals' Perceptions of the Working Conditions in North Carolina Elementary Schools and Student Achievement

    ERIC Educational Resources Information Center

    Mizzelle, Sylvia Jean

    2012-01-01

    The purpose of this study was to examine the relationship between teachers' and principals' perceptions on the North Carolina Teacher Working Conditions Survey (TWC) and the influence this relationship had on student achievement. A quantitative research design using a Multiple Linear Regression investigated the relationship between teachers' and…

  6. 37 CFR 251.34 - Gifts and other things of monetary value.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... under circumstances in which it is clear that the gift is motivated by a family relationship or personal... relationship to the arbitrator, or (2) Given to any other person, including any charitable organization, on the...

  7. Femtosecond pulses propagation through pure water

    NASA Astrophysics Data System (ADS)

    Naveira, Lucas; Sokolov, Alexei; Byeon, Joong-Hyeok; Kattawar, George

    2007-10-01

    Recently, considerable attention has been dedicated to the field of optical precursors, which can possibly be applied to long-distance underwater communications. Input beam intensities have been carefully adjusted to keep experiments in the linear regime, and some experiments have shown violation of the Beer-Lambert law. We are presently carrying out experiments using femtosecond laser pulses propagating through pure water strictly in the linear regime to study this interesting and important behavior. We are also employing several new and innovative schemes to more clearly define the phenomena.

  8. Application of linearized inverse scattering methods for the inspection in steel plates embedded in concrete structures

    NASA Astrophysics Data System (ADS)

    Tsunoda, Takaya; Suzuki, Keigo; Saitoh, Takahiro

    2018-04-01

    This study develops a method to visualize the state of steel-concrete interface with ultrasonic testing. Scattered waves are obtained by the UT pitch-catch mode from the surface of the concrete. Discrete wavelet transform is applied in order to extract echoes scattered from the steel-concrete interface. Then Linearized Inverse Scattering Methods are used for imaging the interface. The results show that LISM with Born and Kirchhoff approximation provide clear images for the target.

  9. The Profile-Query Relationship.

    ERIC Educational Resources Information Center

    Shepherd, Michael A.; Phillips, W. J.

    1986-01-01

    Defines relationship between user profile and user query in terms of relationship between clusters of documents retrieved by each, and explores the expression of cluster similarity and cluster overlap as linear functions of similarity existing between original pairs of profiles and queries, given the desired retrieval threshold. (23 references)…

  10. Soil moisture in relation to geologic structure and lithology, northern California

    NASA Technical Reports Server (NTRS)

    Rich, E. I. (Principal Investigator)

    1980-01-01

    The author has identified the following significant results. Structural features in the Norther California Coast Ranges are clearly discernable on Nite-IR images and some of the structural linears may results in an extension of known faults within the region. The Late Mesozoic marine sedimentary rocks along the western margin of the Sacramento Valley are clearly defined on the Nite-IR images and in a gross way individual layers of sandstone can be differentiated from shale. Late Pleistocene alluvial fans are clearly differentiated from second generation Holocene fans on the basis of tonal characteristics. Although the tonal characteristics change with the seasons, the differentiation of the two sets of fans is still possible.

  11. [Preliminary analysis on relationship between traditional efficacy of Chinese medicine and modern pharmacological action].

    PubMed

    Ren, Jun-Guo; Wang, Dong-Zhi; Lei, Lei; Kang, Li; Liu, Jian-Xun

    2017-05-01

    To find the relationship between traditional efficacy of Chinese medicine and modern pharmacological action by using data mining, and provide information and reference for further research and development for the pharmacology research of traditional Chinese medicine.The information of 547 kinds of traditional Chinese medicines, 335 kinds of Chinese medicine effects and 86 kinds of pharmacological actions were collected and processed in Clinical Guide to the Chinese Pharmacopoeia published in 2010; Access and Excel software were used to analyze the frequence and frequency of single effect, pharmacological action, and both. In addition, the relationship between efficacy and pharmacology was analyzed with the clearing heat and antibacterial effects as the example. The analysis results showed that 547 kinds of Chinese medicines involved 335 kinds of Chinese medicine effects and 86 kinds of pharmacological actions. Among them, the most frequent Chinese medicine effect was"clearing heat", whose frequence was 130 and the frequency was 0.24; the most frequent pharmacological action was "anti-inflammatory action" whose frequence was 191 and the frequency was 0.35. The most common efficacy-pharmacological action group was "clearing heat" and "anti-bacterial action", whose frequence was 75 and the frequency was 0.26. The couple of "purgation" and "cathartic effect" had the largest frequency of 0.30, but they just appeared together for 3 times. There were 52 kinds of pharmacological actions that occurred together with clearing heat, of which, the top 10 were anti-bacterial action, anti-inflammatory action, antineoplastic action, anti-hepatic injury action, immunoregulation action, antipyretic action, antiviralaction, hypoglycemic action, antioxidant action and analgesic action. There were 161 kinds of Chinese medicine effects that occurred together with anti-bacterial action, of which, the top 10 were clearing heat, detoxification, detumescence, analgesia, resolving dampness, pesticide, cooling blood, expelling wind, eliminating dampness and hemostasis. These results suggested that there was a certain relationship between traditional Chinese medicine effects and modern pharmacological actions. Copyright© by the Chinese Pharmaceutical Association.

  12. Compulsive Internet use: the role of online gaming and other internet applications.

    PubMed

    van Rooij, Antonius J; Schoenmakers, Tim M; van de Eijnden, Regina J J M; van de Mheen, Dike

    2010-07-01

    Increasing research on Internet addiction makes it necessary to distinguish between the medium of Internet and its specific applications. This study explores the relationship between time spent on various Internet applications (including online gaming) and Compulsive Internet Use in a large sample of adolescents. The 2007 (N=4,920) and 2008 (N=4,753) samples of a longitudinal survey study among adolescents were used, as well as the 2007-2008 cohort subsample (N=1421). Compulsive Internet Use was predicted from the time spent on the various Internet applications in two cross-sectional multiple linear regression models and one longitudinal regression model in which changes in behavior were related to changes in Compulsive Internet Use. In both samples, downloading, social networking, MSN use, Habbo Hotel, chatting, blogging, online games, and casual games were shown to be associated with Compulsive Internet Use. Off these, online gaming was shown to have the strongest association with Compulsive Internet Use. Moreover, changes in online gaming were most strongly associated with changes in Compulsive Internet Use over time for the longitudinal cohort. A clear relationship was shown between online gaming and Compulsive Internet Use. It is further argued that a subgroup of compulsive Internet users should be classified as compulsive online gamers. Copyright (c) 2010 Society for Adolescent Health and Medicine. Published by Elsevier Inc. All rights reserved.

  13. The concurrent and longitudinal associations of temperament and nutritional risk factors in early childhood.

    PubMed

    van den Heuvel, M; Chen, Y; Abdullah, K; Maguire, J L; Parkin, P C; Birken, C S

    2017-12-01

    Early childhood temperament is increasingly recognized as an important attribute that may impact screen time use, outdoor play and childhood obesity. The relationship between temperament and nutrition in preschool children is less clear. The objective of the study is to investigate if temperament dimensions (negative affectivity, effortful control and surgency) in early childhood are associated with nutritional risk factors. Six hundred seventy-eight children were followed (mean age at baseline visit 3.1 years; mean time to follow-up 16.5 months). Parents reported on child temperament and nutritional risk factors during regularly scheduled well-child clinic visits. A mixed effect model demonstrated a significant association between higher negative affectivity (1.03; 95% CI 0.69 to 1.37) and higher effortful control (-0.88; 95% CI -1.27 to -0.49) on concurrent nutritional risk, independent of covariates. Multivariate linear regression analysis identified that higher effortful control, and not negative affectivity, was significantly associated with a decrease in nutritional risk (-0.67; 95% CI -1.10 to -0.24) over time, independent of covariates. There was no relationship identified between surgency and nutritional risk. Three-year-old children with higher effortful control had reduced nutritional risk at 5 years of age. Future nutritional risk prevention strategies may benefit from interventions to increase effortful control in early childhood. © 2016 World Obesity Federation.

  14. Non-invasive imaging of the levels and effects of glutathione on the redox status of mouse brain using electron paramagnetic resonance imaging.

    PubMed

    Emoto, Miho C; Matsuoka, Yuta; Yamada, Ken-Ichi; Sato-Akaba, Hideo; Fujii, Hirotada G

    2017-04-15

    Glutathione (GSH) is the most abundant non-protein thiol that buffers reactive oxygen species in the brain. GSH does not reduce nitroxides directly, but in the presence of ascorbates, addition of GSH increases ascorbate-induced reduction of nitroxides. In this study, we used electron paramagnetic resonance (EPR) imaging and the nitroxide imaging probe, 3-methoxycarbonyl-2,2,5,5-tetramethyl-piperidine-1-oxyl (MCP), to non-invasively obtain spatially resolved redox data from mouse brains depleted of GSH with diethyl maleate compared to control. Based on the pharmacokinetics of the reduction reaction of MCP in the mouse heads, the pixel-based rate constant of its reduction reaction was calculated as an index of the redox status in vivo and mapped as a "redox map". The obtained redox maps from control and GSH-depleted mouse brains showed a clear change in the brain redox status, which was due to the decreased levels of GSH in brains as measured by a biochemical assay. We observed a linear relationship between the reduction rate constant of MCP and the level of GSH for both control and GSH-depleted mouse brains. Using this relationship, the GSH level in the brain can be estimated from the redox map obtained with EPR imaging. Copyright © 2017 Elsevier Inc. All rights reserved.

  15. Linking terrestrial P inputs to riverine export across the United ...

    EPA Pesticide Factsheets

    Human beings have greatly accelerated phosphorus (P) flows from land to aquatic ecosystems, often resulting in eutrophication, harmful algal blooms, and hypoxia. Although a variety of statistical and mechanistic models have been used to explore the relationship between terrestrial nutrient management and losses to waterways, our understanding of how natural and anthropogenic landscape characteristics mediate losses of P from watersheds lags behind that of nitrogen. The need for higher resolution data is often identified as an important barrier that limits our capacity to predict P loading. In order to address this gap, we constructed spatially explicit datasets of terrestrial P inputs and outputs (fertilizer, confined manure, crop harvest and sewage) across the continental U.S. for 2012. We then examined how these P sources, along with climate, hydrology, and land use, influenced P exports from 72 watersheds as total P (TP) and dissolved inorganic P (DIP) concentrations and yields, and TP fractional export. TP and DIP concentrations and TP yields were best correlated with runoff, but using simple linear regression, we were not able to explain more than 56% of the variance in any of the water quality variables (TP fractional export vs P manure inputs). The lack of clear and strong relationships between contemporary, high-resolution, anthropogenic, terrestrial P and riverine P export at the national scale highlights the fact that a complex suite of factors mediat

  16. Hapten-antibody recognition studies in competitive immunoassay of α-zearalanol analogs by computational chemistry and Pearson Correlation analysis.

    PubMed

    Wang, Zhanhui; Luo, Pengjie; Cheng, Linli; Zhang, Suxia; Shen, Jianzhong

    2011-01-01

    The molecular recognition of hapten-antibody is a fundamental event in competitive immunoassay, which guarantees the sensitivity and specificity of immunoassay for the detection of haptens. The aim of this study is to investigate the correlation between binding ability of one monoclonal antibody, 1H9B4, recognizing and the molecular aspects of α-zearalanol analogs. The mouse-derived monoclonal antibody was produced by using α-zearalanol conjugated to bovine serum albumin as an immunogen. The antibody recognition abilities, expressed as IC(50) values, were determined by a competitive ELISA. All of the hapten molecules were optimized by Density Function Theory (DFT) at B3LYP/ 6-31G* level and the conformation and electrostatic molecular isosurface were employed to explain the molecular recognition between α-zearalanol analogs and antibody 1H9B4. Pearson Correlation analysis between molecular descriptors and IC(50) values was qualitatively undertaken and the results showed that one molecular descriptor, surface of the hapten molecule, clearly demonstrated linear relationship with antibody recognition ability, where the relationship coefficient was 0.88 and the correlation was significant at p < 0.05 level. The study shows that computational chemistry and Pearson Correlation analysis can be used as tool to help the immunochemistries better understand the processing of antibody recognition of hapten molecules in competitive immunoassay. Copyright © 2011 John Wiley & Sons, Ltd.

  17. Bioconcentration of lipophilic compounds by some aquatic organisms

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hawker, D.W.; Connell, D.W.

    1986-04-01

    With nondegradable, lipophilic compounds having log P values ranging from 2 to 6, direct linear relationships have been found between the logarithms of the equilibrium bioconcentration factors, and also reciprocal clearance rate constants, with log P for daphnids and molluscs. These relationships permit calculation of the times required for equilibrium and significant bioconcentration of lipophilic chemicals. Compared with fish, these time periods are successively shorter for molluscs, then daphnids. The equilibrium biotic concentration was found to decrease with increasing chemical hydrophobicity for both molluscs and daphnids. Also, new linear relationships between the logarithm of the bioconcentration factor and log Pmore » were found for compounds not attaining equilibrium within finite exposure times.« less

  18. Kinetics of microstructure formation of high-pressure induced gel from a whey protein isolate

    NASA Astrophysics Data System (ADS)

    He, Jin-Song; Yang, Hongwei; Zhu, Wanpeng; Mu, Tai-Hua

    2010-03-01

    The kinetic process of pressure-induced gelation of whey protein isolate (WPI) solutions was studied using in situ light scattering. The relationship of the logarithm of scattered light intensity (I) versus time (t) was linear after the induced time and could be described by the Cahn-Hilliard linear theory. With increasing time, the scattered intensity deviated from the exponential relationship, and the time evolution of the scattered light intensity maximum Im and the corresponding wavenumber qm could be described in terms of the power-law relationship as Im~fβ and qm~f-α, respectively. These results indicated that phase separation occurred during the gelation of WPI solutions under high pressure.

  19. Linear solvation energy relationships: "rule of thumb" for estimation of variable values

    USGS Publications Warehouse

    Hickey, James P.; Passino-Reader, Dora R.

    1991-01-01

    For the linear solvation energy relationship (LSER), values are listed for each of the variables (Vi/100, π*, &betam, αm) for fundamental organic structures and functional groups. We give the guidelines to estimate LSER variable values quickly for a vast array of possible organic compounds such as those found in the environment. The difficulty in generating these variables has greatly discouraged the application of this quantitative structure-activity relationship (QSAR) method. This paper present the first compilation of molecular functional group values together with a utilitarian set of the LSER variable estimation rules. The availability of these variable values and rules should facilitate widespread application of LSER for hazard evaluation of environmental contaminants.

  20. Do Stress Trajectories Predict Mortality in Older Men? Longitudinal Findings from the VA Normative Aging Study

    PubMed Central

    Aldwin, Carolyn M.; Molitor, Nuoo-Ting; Avron, Spiro; Levenson, Michael R.; Molitor, John; Igarashi, Heidi

    2011-01-01

    We examined long-term patterns of stressful life events (SLE) and their impact on mortality contrasting two theoretical models: allostatic load (linear relationship) and hormesis (inverted U relationship) in 1443 NAS men (aged 41–87 in 1985; M = 60.30, SD = 7.3) with at least two reports of SLEs over 18 years (total observations = 7,634). Using a zero-inflated Poisson growth mixture model, we identified four patterns of SLE trajectories, three showing linear decreases over time with low, medium, and high intercepts, respectively, and one an inverted U, peaking at age 70. Repeating the analysis omitting two health-related SLEs yielded only the first three linear patterns. Compared to the low-stress group, both the moderate and the high-stress groups showed excess mortality, controlling for demographics and health behavior habits, HRs = 1.42 and 1.37, ps <.01 and <.05. The relationship between stress trajectories and mortality was complex and not easily explained by either theoretical model. PMID:21961066

  1. On Spectral Invariance of Single Scattering Albedo for Water Droplets and Ice Crystals at Weakly Absorbing Wavelengths

    NASA Technical Reports Server (NTRS)

    Marshak, Alexander; Knyazikhin, Yuri; Chiu, J. Christine; Wiscombe, Warren J.

    2012-01-01

    The single scattering albedo omega(sub O lambda) in atmospheric radiative transfer is the ratio of the scattering coefficient to the extinction coefficient. For cloud water droplets both the scattering and absorption coefficients, thus the single scattering albedo, are functions of wavelength lambda and droplet size r. This note shows that for water droplets at weakly absorbing wavelengths, the ratio omega(sub O lambda)(r)/omega(sub O lambda)(r (sub O)) of two single scattering albedo spectra is a linear function of omega(sub O lambda)(r). The slope and intercept of the linear function are wavelength independent and sum to unity. This relationship allows for a representation of any single scattering albedo spectrum omega(sub O lambda)(r) via one known spectrum omega(sub O lambda)(r (sub O)). We provide a simple physical explanation of the discovered relationship. Similar linear relationships were found for the single scattering albedo spectra of non-spherical ice crystals.

  2. Development of a novel in silico model of zeta potential for metal oxide nanoparticles: a nano-QSPR approach

    NASA Astrophysics Data System (ADS)

    Wyrzykowska, Ewelina; Mikolajczyk, Alicja; Sikorska, Celina; Puzyn, Tomasz

    2016-11-01

    Once released into the aquatic environment, nanoparticles (NPs) are expected to interact (e.g. dissolve, agglomerate/aggregate, settle), with important consequences for NP fate and toxicity. A clear understanding of how internal and environmental factors influence the NP toxicity and fate in the environment is still in its infancy. In this study, a quantitative structure-property relationship (QSPR) approach was employed to systematically explore factors that affect surface charge (zeta potential) under environmentally realistic conditions. The nano-QSPR model developed with multiple linear regression (MLR) was characterized by high robustness ({{{Q}}{{2}}}{{CV}}=0.90) and external predictivity ({{{Q}}{{2}}}{{EXT}}=0.93). The results clearly showed that zeta potential values varied markedly as functions of the ionic radius of the metal atom in the metal oxides, confirming that agglomeration and the extent of release of free MexOy largely depend on their intrinsic properties. A developed nano-QSPR model was successfully applied to predict zeta potential in an ionized solution of NPs for which experimentally determined values of response have been unavailable. Hence, the application of our model is possible when the values of zeta potential in the ionized solution for metal oxide nanoparticles are undetermined, without the necessity of performing more time consuming and expensive experiments. We believe that our studies will be helpful in predicting the conditions under which MexOy is likely to become problematic for the environment and human health.

  3. Integration of epidemiology into the genetic analysis of mastitis in Swedish Holstein.

    PubMed

    Windig, Jack J; Urioste, Jorge I; Strandberg, Erling

    2013-04-01

    Heritability of mastitis (and diseases in general) tends to be low. One possible cause is that no clear distinction can be made between resistant and nonresistant animals, because healthy animals include animals that have not been exposed to pathogens and resistant animals. To account for this, we quantified the prevalence of clinical mastitis (CM) and subclinical mastitis (SCM) in 2,069 Swedish Holstein herds as a measure of exposure. Herd prevalence averaged 26.5% for SCM and 6.4% for CM; 61% of the first lactations of 177,309 cows were classified as having at least one case of SCM and 10% as having CM. In a reaction norm approach, heritability of (S)CM was quantified as a function of herd prevalence of (S)CM. The best-fitting model was a second-order polynomial of first-lactation cow SCM as a function of herd prevalence SCM, and a first-order (linear) polynomial of first-lactation cow CM as a function of CM herd prevalence. Heritability for SCM ranged from 0.069 to 0.105 and for CM from 0.016 to 0.032. For both, we found no clear effect of herd prevalence on their heritability. Genetic correlations within traits across herd prevalences were all greater than 0.92. Whether relationships among prevalence, exposure, disease, and genetics were as expected is a matter of discussion, but reaction norm analyses may be a valuable tool for epidemiological genetics. Copyright © 2013 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

  4. An Improved Algorithm for Retrieving Surface Downwelling Longwave Radiation from Satellite Measurements

    NASA Technical Reports Server (NTRS)

    Zhou, Yaping; Kratz, David P.; Wilber, Anne C.; Gupta, Shashi K.; Cess, Robert D.

    2007-01-01

    Zhou and Cess [2001] developed an algorithm for retrieving surface downwelling longwave radiation (SDLW) based upon detailed studies using radiative transfer model calculations and surface radiometric measurements. Their algorithm linked clear sky SDLW with surface upwelling longwave flux and column precipitable water vapor. For cloudy sky cases, they used cloud liquid water path as an additional parameter to account for the effects of clouds. Despite the simplicity of their algorithm, it performed very well for most geographical regions except for those regions where the atmospheric conditions near the surface tend to be extremely cold and dry. Systematic errors were also found for scenes that were covered with ice clouds. An improved version of the algorithm prevents the large errors in the SDLW at low water vapor amounts by taking into account that under such conditions the SDLW and water vapor amount are nearly linear in their relationship. The new algorithm also utilizes cloud fraction and cloud liquid and ice water paths available from the Cloud and the Earth's Radiant Energy System (CERES) single scanner footprint (SSF) product to separately compute the clear and cloudy portions of the fluxes. The new algorithm has been validated against surface measurements at 29 stations around the globe for Terra and Aqua satellites. The results show significant improvement over the original version. The revised Zhou-Cess algorithm is also slightly better or comparable to more sophisticated algorithms currently implemented in the CERES processing and will be incorporated as one of the CERES empirical surface radiation algorithms.

  5. Biostatistics Series Module 6: Correlation and Linear Regression.

    PubMed

    Hazra, Avijit; Gogtay, Nithya

    2016-01-01

    Correlation and linear regression are the most commonly used techniques for quantifying the association between two numeric variables. Correlation quantifies the strength of the linear relationship between paired variables, expressing this as a correlation coefficient. If both variables x and y are normally distributed, we calculate Pearson's correlation coefficient ( r ). If normality assumption is not met for one or both variables in a correlation analysis, a rank correlation coefficient, such as Spearman's rho (ρ) may be calculated. A hypothesis test of correlation tests whether the linear relationship between the two variables holds in the underlying population, in which case it returns a P < 0.05. A 95% confidence interval of the correlation coefficient can also be calculated for an idea of the correlation in the population. The value r 2 denotes the proportion of the variability of the dependent variable y that can be attributed to its linear relation with the independent variable x and is called the coefficient of determination. Linear regression is a technique that attempts to link two correlated variables x and y in the form of a mathematical equation ( y = a + bx ), such that given the value of one variable the other may be predicted. In general, the method of least squares is applied to obtain the equation of the regression line. Correlation and linear regression analysis are based on certain assumptions pertaining to the data sets. If these assumptions are not met, misleading conclusions may be drawn. The first assumption is that of linear relationship between the two variables. A scatter plot is essential before embarking on any correlation-regression analysis to show that this is indeed the case. Outliers or clustering within data sets can distort the correlation coefficient value. Finally, it is vital to remember that though strong correlation can be a pointer toward causation, the two are not synonymous.

  6. Biostatistics Series Module 6: Correlation and Linear Regression

    PubMed Central

    Hazra, Avijit; Gogtay, Nithya

    2016-01-01

    Correlation and linear regression are the most commonly used techniques for quantifying the association between two numeric variables. Correlation quantifies the strength of the linear relationship between paired variables, expressing this as a correlation coefficient. If both variables x and y are normally distributed, we calculate Pearson's correlation coefficient (r). If normality assumption is not met for one or both variables in a correlation analysis, a rank correlation coefficient, such as Spearman's rho (ρ) may be calculated. A hypothesis test of correlation tests whether the linear relationship between the two variables holds in the underlying population, in which case it returns a P < 0.05. A 95% confidence interval of the correlation coefficient can also be calculated for an idea of the correlation in the population. The value r2 denotes the proportion of the variability of the dependent variable y that can be attributed to its linear relation with the independent variable x and is called the coefficient of determination. Linear regression is a technique that attempts to link two correlated variables x and y in the form of a mathematical equation (y = a + bx), such that given the value of one variable the other may be predicted. In general, the method of least squares is applied to obtain the equation of the regression line. Correlation and linear regression analysis are based on certain assumptions pertaining to the data sets. If these assumptions are not met, misleading conclusions may be drawn. The first assumption is that of linear relationship between the two variables. A scatter plot is essential before embarking on any correlation-regression analysis to show that this is indeed the case. Outliers or clustering within data sets can distort the correlation coefficient value. Finally, it is vital to remember that though strong correlation can be a pointer toward causation, the two are not synonymous. PMID:27904175

  7. A meta-analysis of cambium phenology and growth: linear and non-linear patterns in conifers of the northern hemisphere

    PubMed Central

    Rossi, Sergio; Anfodillo, Tommaso; Čufar, Katarina; Cuny, Henri E.; Deslauriers, Annie; Fonti, Patrick; Frank, David; Gričar, Jožica; Gruber, Andreas; King, Gregory M.; Krause, Cornelia; Morin, Hubert; Oberhuber, Walter; Prislan, Peter; Rathgeber, Cyrille B. K.

    2013-01-01

    Background and Aims Ongoing global warming has been implicated in shifting phenological patterns such as the timing and duration of the growing season across a wide variety of ecosystems. Linear models are routinely used to extrapolate these observed shifts in phenology into the future and to estimate changes in associated ecosystem properties such as net primary productivity. Yet, in nature, linear relationships may be special cases. Biological processes frequently follow more complex, non-linear patterns according to limiting factors that generate shifts and discontinuities, or contain thresholds beyond which responses change abruptly. This study investigates to what extent cambium phenology is associated with xylem growth and differentiation across conifer species of the northern hemisphere. Methods Xylem cell production is compared with the periods of cambial activity and cell differentiation assessed on a weekly time scale on histological sections of cambium and wood tissue collected from the stems of nine species in Canada and Europe over 1–9 years per site from 1998 to 2011. Key Results The dynamics of xylogenesis were surprisingly homogeneous among conifer species, although dispersions from the average were obviously observed. Within the range analysed, the relationships between the phenological timings were linear, with several slopes showing values close to or not statistically different from 1. The relationships between the phenological timings and cell production were distinctly non-linear, and involved an exponential pattern Conclusions The trees adjust their phenological timings according to linear patterns. Thus, shifts of one phenological phase are associated with synchronous and comparable shifts of the successive phases. However, small increases in the duration of xylogenesis could correspond to a substantial increase in cell production. The findings suggest that the length of the growing season and the resulting amount of growth could respond differently to changes in environmental conditions. PMID:24201138

  8. Investigating the linearity assumption between lumber grade mix and yield using design of experiments (DOE)

    Treesearch

    Xiaoqiu Zuo; Urs Buehlmann; R. Edward Thomas

    2004-01-01

    Solving the least-cost lumber grade mix problem allows dimension mills to minimize the cost of dimension part production. This problem, due to its economic importance, has attracted much attention from researchers and industry in the past. Most solutions used linear programming models and assumed that a simple linear relationship existed between lumber grade mix and...

  9. Problem Based Learning Technique and Its Effect on Acquisition of Linear Programming Skills by Secondary School Students in Kenya

    ERIC Educational Resources Information Center

    Nakhanu, Shikuku Beatrice; Musasia, Amadalo Maurice

    2015-01-01

    The topic Linear Programming is included in the compulsory Kenyan secondary school mathematics curriculum at form four. The topic provides skills for determining best outcomes in a given mathematical model involving some linear relationship. This technique has found application in business, economics as well as various engineering fields. Yet many…

  10. Linear and Nonlinear Analysis of Brain Dynamics in Children with Cerebral Palsy

    ERIC Educational Resources Information Center

    Sajedi, Firoozeh; Ahmadlou, Mehran; Vameghi, Roshanak; Gharib, Masoud; Hemmati, Sahel

    2013-01-01

    This study was carried out to determine linear and nonlinear changes of brain dynamics and their relationships with the motor dysfunctions in CP children. For this purpose power of EEG frequency bands (as a linear analysis) and EEG fractality (as a nonlinear analysis) were computed in eyes-closed resting state and statistically compared between 26…

  11. Defining a Family of Cognitive Diagnosis Models Using Log-Linear Models with Latent Variables

    ERIC Educational Resources Information Center

    Henson, Robert A.; Templin, Jonathan L.; Willse, John T.

    2009-01-01

    This paper uses log-linear models with latent variables (Hagenaars, in "Loglinear Models with Latent Variables," 1993) to define a family of cognitive diagnosis models. In doing so, the relationship between many common models is explicitly defined and discussed. In addition, because the log-linear model with latent variables is a general model for…

  12. 17 CFR 240.17a-22 - Supplemental material of registered clearing agencies.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... a significant relationship, such as pledgees, transfer agents, or self-regulatory organizations, any... clearing agency for which the Commission is not the appropriate regulatory agency shall at the same time file one copy of such material with its appropriate regulatory agency. [45 FR 73914, Nov. 7, 1980] ...

  13. How Well Do SiF And Other Vegetation Spectral Indices Track Temporal Variations of Canopy Photosynthesis in A Paddy Rice

    NASA Astrophysics Data System (ADS)

    Kaige, Y.; Ryu, Y.; Kimm, H.; Huang, Y.; Jiang, C.; Hwang, Y.; Kim, J.; Kang, M.

    2016-12-01

    Recent advancements in remote sensing of SiF opened new opportunities to directly estimate canopy photosynthesis at regional scales. Observing SiF at canopy scale in the field, however, is at very initial stage. In this study, we report SiF and hyperspectral reflectance (400-900 nm) data concurrently measured every 10 sec across the whole growing season in a paddy rice, South Korea. The study site experienced water management via irrigation and drainage and showed a peak LAI of 7. We test whether SiF and a range of different vegetation spectral indices (VIs) well capture half-hourly variations in canopy photosynthesis quantified from an eddy flux tower. During the growing season, we found that SiF showed tight linear relationship to APAR (r2=0.7), and moderate linear relationship to GPP (r2=0.5). Both NDVI, EVI and PRI showed logarithmic relationships to GPP (r2<0.5) and were all saturated at LAI>4. SiF showed linear relationship to GPP even at higher LAI. We conclude that SiF is a better index in predicting temporal variations in canopy photosynthesis than the other VIs in the paddy rice site.

  14. The relations between conscientiousness and mental health in a North-European and a West-Asian culture.

    PubMed

    Farahani, Mohammad-Naghy; Kormi-Nouri, Reza; De Raad, Boele

    2017-07-04

    The relationship between conscientiousness, mental health and mental illness has been an issue for the last two decades. By using a dual model of mental health, the present study examined a non-linear relationship between conscientiousness and healthy or non-healthy symptoms in two different cultures. Participants in this study were 296 Iranian and 310 Swedish university students (18-24 years of age). We used two different conscientiousness scales; the 12-item conscientiousness subscale of the NEO/FFI as an imported (etic) scale, and a 10-item Iranian conscientiousness scale as an indigenous (emic) and culture-dependent scale. In both conscientiousness scales, multivariate analysis of variance showed that conscientiousness differentiated among four mental health groups (languishing, troubled, symptomatic and flourishing), although languishing and troubled individuals were less conscientious than flourishing and symptomatic individuals. Furthermore, the non-healthy symptomatic individuals were more conscientiousness than flourishing individuals. The results showed no significant differences between the two cultures in terms of the four mental health categories. It was concluded that the relationship between conscientiousness and mental health/mental illness is more a non-linear relationship than a linear one.

  15. Bayesian dynamical systems modelling in the social sciences.

    PubMed

    Ranganathan, Shyam; Spaiser, Viktoria; Mann, Richard P; Sumpter, David J T

    2014-01-01

    Data arising from social systems is often highly complex, involving non-linear relationships between the macro-level variables that characterize these systems. We present a method for analyzing this type of longitudinal or panel data using differential equations. We identify the best non-linear functions that capture interactions between variables, employing Bayes factor to decide how many interaction terms should be included in the model. This method punishes overly complicated models and identifies models with the most explanatory power. We illustrate our approach on the classic example of relating democracy and economic growth, identifying non-linear relationships between these two variables. We show how multiple variables and variable lags can be accounted for and provide a toolbox in R to implement our approach.

  16. Implicit Wiener series analysis of epileptic seizure recordings.

    PubMed

    Barbero, Alvaro; Franz, Matthias; van Drongelen, Wim; Dorronsoro, José R; Schölkopf, Bernhard; Grosse-Wentrup, Moritz

    2009-01-01

    Implicit Wiener series are a powerful tool to build Volterra representations of time series with any degree of non-linearity. A natural question is then whether higher order representations yield more useful models. In this work we shall study this question for ECoG data channel relationships in epileptic seizure recordings, considering whether quadratic representations yield more accurate classifiers than linear ones. To do so we first show how to derive statistical information on the Volterra coefficient distribution and how to construct seizure classification patterns over that information. As our results illustrate, a quadratic model seems to provide no advantages over a linear one. Nevertheless, we shall also show that the interpretability of the implicit Wiener series provides insights into the inter-channel relationships of the recordings.

  17. The Relationships between School Poverty and Student Achievement in Maine

    ERIC Educational Resources Information Center

    Silvernail, David L.; Sloan, James E.; Paul, Chelsea R.; Johnson, Amy F.; Stump, Erika K.

    2014-01-01

    The goal of this study was to examine the relationships between school level poverty found in Maine schools and student academic performance. The evidence clearly shows that there is a relationship. As the percent of poverty increases in a school, student performance declines. But the poverty level alone does not explain the wide variations in…

  18. A Relationship Between Visible and Near-IR Global Spectral Reflectance based on DSCOVR/EPIC

    NASA Astrophysics Data System (ADS)

    Wen, G.; Marshak, A.; Song, W.; Knyazikhin, Y.

    2017-12-01

    The launch of Deep Space Climate Observatory (DSCOVR) to the Earth's first Lagrange point (L1) allows us to see a new perspective of the Earth. The Earth Polychromatic Imaging Camera (EPIC) on the DSCOVR measures the back scattered radiation of the entire sunlit side of the Earth at 10 narrow band wavelengths ranging from ultraviolet to visible and near-infrared. We analyzed EPIC global averaged reflectance data. We found that the global averaged visible reflectance has a unique non-linear relationship with near infrared (NIR) reflectance. This non-linear relationship was not observed by any other satellite observations due to a limited spatial and temporal coverage of either low earth orbit (LEO) or geostationary satellite. The non-linear relationship is associated with the changing in the coverages of ocean, cloud, land, and vegetation as the Earth rotates. We used Terra and Aqua MODIS daily global radiance data to simulate EPIC observations. Since MODIS samples the Earth in a limited swath (2330km cross track) at a specific local time (10:30 am for Terra, 1:30 pm for Aqua) with approximately 15 orbits per day, the global average reflectance at a given time may be approximated by averaging the reflectance in the MODIS nearest-time swaths in the sunlit hemisphere. We found that MODIS simulated global visible and NIR spectral reflectance captured the major feature of the EPIC observed non-linear relationship with some errors. The difference between the two is mainly due to the sampling limitation of polar satellite. This suggests that that EPIC observations can be used to reconstruct MODIS global average reflectance time series for studying Earth system change in the past decade.

  19. Potential Impacts of Urban Land Expansion on Asian Outflows of Air Pollutants

    NASA Astrophysics Data System (ADS)

    Wei, T.; Liu, J.; Tao, S.; Ban-Weiss, G. A.

    2016-12-01

    We investigate the impacts of urban land expansion over Eastern China (EC) on the export of black carbon (BC), carbon monoxide (CO) and ozone (O3) to the West Pacific during the January, April, July and October of 2009, using WRF/Chem model coupled with the tracers tagging technique and an up-to-date single layer urban canopy scheme updated with the treatment of urban hydrological processes. Our model simulations could reproduce well the vertical profiles of Asian outflows of BC and CO observed during the A-FORCE period (March to April of 2009). Over urbanizing areas, increment in urban land fraction could linearly elevate primary pollutants from the lower boundary layer to higher altitudes, and perturb the thermal, hydrological, and kinetic exchange processes between land surface and the atmosphere aloft through all seasons (such local impacts highest in July but lowest in January). Furthermore, we find robust linear relationships exist between urban land fraction (averaged over EC) and export of BC emitted from EC across meridional planes over the western Pacific (e.g., 140 °E). Specifically, each 10% increase in urban land fraction over EC enhances the eastward mass fluxes of BC by about 5%-10% in January and July, and 10%-20% in April and October, respectively, in the free troposphere, which is the dominant pathway for Asian outflows. Such a linear relationship is relatively weaker for CO and only appears in April and October. The different response patterns between BC and CO arise from their distinct physical and chemical properties. Even with decreased vegetation (and reduced biogenic emissions), the O3­ concentrations at the surface and 800 hPa over urbanizing areas both tend to increase. However, no clear trend is observed for the export of O3 over West Pacific for all four months. Urban land expansion facilitates the uplift of local pollutants, but also changes the large-scale circulation pattern (the perturbation cyclone over the downwind Pacific acts to impede the eastward transpacific transport), both playing important roles on the efficiency that Asian emissions are exported. Our finding indicates that the extensive urban land expansion would significantly impact the local climate and air quality, which also have a large impact on long-range transboundary transport.

  20. TiO2 dye sensitized solar cell (DSSC): linear relationship of maximum power point and anthocyanin concentration

    NASA Astrophysics Data System (ADS)

    Ahmadian, Radin

    2010-09-01

    This study investigated the relationship of anthocyanin concentration from different organic fruit species and output voltage and current in a TiO2 dye-sensitized solar cell (DSSC) and hypothesized that fruits with greater anthocyanin concentration produce higher maximum power point (MPP) which would lead to higher current and voltage. Anthocyanin dye solution was made with crushing of a group of fresh fruits with different anthocyanin content in 2 mL of de-ionized water and filtration. Using these test fruit dyes, multiple DSSCs were assembled such that light enters through the TiO2 side of the cell. The full current-voltage (I-V) co-variations were measured using a 500 Ω potentiometer as a variable load. Point-by point current and voltage data pairs were measured at various incremental resistance values. The maximum power point (MPP) generated by the solar cell was defined as a dependent variable and the anthocyanin concentration in the fruit used in the DSSC as the independent variable. A regression model was used to investigate the linear relationship between study variables. Regression analysis showed a significant linear relationship between MPP and anthocyanin concentration with a p-value of 0.007. Fruits like blueberry and black raspberry with the highest anthocyanin content generated higher MPP. In a DSSC, a linear model may predict MPP based on the anthocyanin concentration. This model is the first step to find organic anthocyanin sources in the nature with the highest dye concentration to generate energy.

  1. In vitro function of the aryl hydrocarbon receptor predicts in ...

    EPA Pesticide Factsheets

    Differences in sensitivity to dioxin-like compounds (DLCs) among species and taxa presents a major challenge to ecological risk assessments. Activation of the aryl hydrocarbon receptor (AHR) regulates adverse effects associated with exposure to DLCs in vertebrates. Prior investigations demonstrated that sensitivity to activation of the AHR1 (50% effect concentration; EC50) in an in vitro luciferase reporter gene (LRG) assay was predictive of the sensitivity of embryos (lethal dose to cause 50% lethality; LD50) across all species of birds for all DLCs. However, nothing was known about whether sensitivity to activation of the AHR is predictive of sensitivity of embryos of fishes to DLCs. Therefore, this study investigated in vitro sensitivities of AHR1s and AHR2s to the model DLC, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), among eight species of fish of known sensitivities of embryos to TCDD. AHR1s and AHR2s of all fishes were activated by TCDD in vitro. There was no significant linear relationship between in vitro sensitivity of AHR1 and in vivo sensitivity among the investigated fishes (R2 = 0.33, p = 0.23). However, there was a significant linear relationship between in vitro sensitivity of AHR2 and in vivo sensitivity among the investigated fishes (R2 = 0.97, p = < 0.0001). The linear relationship between in vitro sensitivity of AHR2 and in vivo sensitivity of embryos among fishes was compared to the previously generated linear relationship between in vitro s

  2. Electric field metrology for SI traceability: Systematic measurement uncertainties in electromagnetically induced transparency in atomic vapor

    NASA Astrophysics Data System (ADS)

    Holloway, Christopher L.; Simons, Matt T.; Gordon, Joshua A.; Dienstfrey, Andrew; Anderson, David A.; Raithel, Georg

    2017-06-01

    We investigate the relationship between the Rabi frequency (ΩRF, related to the applied electric field) and Autler-Townes (AT) splitting, when performing atom-based radio-frequency (RF) electric (E) field strength measurements using Rydberg states and electromagnetically induced transparency (EIT) in an atomic vapor. The AT splitting satisfies, under certain conditions, a well-defined linear relationship with the applied RF field amplitude. The EIT/AT-based E-field measurement approach derived from these principles is currently being investigated by several groups around the world as a means to develop a new SI-traceable RF E-field measurement technique. We establish conditions under which the measured AT-splitting is an approximately linear function of the RF electric field. A quantitative description of systematic deviations from the linear relationship is key to exploiting EIT/AT-based atomic-vapor spectroscopy for SI-traceable field measurement. We show that the linear relationship is valid and can be used to determine the E-field strength, with minimal error, as long as the EIT linewidth is small compared to the AT-splitting. We also discuss interesting aspects of the thermal dependence (i.e., hot- versus cold-atom) of this EIT-AT technique. An analysis of the transition from cold- to hot-atom EIT in a Doppler-mismatched cascade system reveals a significant change of the dependence of the EIT linewidth on the optical Rabi frequencies and of the AT-splitting on ΩRF.

  3. Causality Analysis of fMRI Data Based on the Directed Information Theory Framework.

    PubMed

    Wang, Zhe; Alahmadi, Ahmed; Zhu, David C; Li, Tongtong

    2016-05-01

    This paper aims to conduct fMRI-based causality analysis in brain connectivity by exploiting the directed information (DI) theory framework. Unlike the well-known Granger causality (GC) analysis, which relies on the linear prediction technique, the DI theory framework does not have any modeling constraints on the sequences to be evaluated and ensures estimation convergence. Moreover, it can be used to generate the GC graphs. In this paper, first, we introduce the core concepts in the DI framework. Second, we present how to conduct causality analysis using DI measures between two time series. We provide the detailed procedure on how to calculate the DI for two finite-time series. The two major steps involved here are optimal bin size selection for data digitization and probability estimation. Finally, we demonstrate the applicability of DI-based causality analysis using both the simulated data and experimental fMRI data, and compare the results with that of the GC analysis. Our analysis indicates that GC analysis is effective in detecting linear or nearly linear causal relationship, but may have difficulty in capturing nonlinear causal relationships. On the other hand, DI-based causality analysis is more effective in capturing both linear and nonlinear causal relationships. Moreover, it is observed that brain connectivity among different regions generally involves dynamic two-way information transmissions between them. Our results show that when bidirectional information flow is present, DI is more effective than GC to quantify the overall causal relationship.

  4. Revisiting the Relationship between Exercise Heart Rate and Music Tempo Preference

    ERIC Educational Resources Information Center

    Karageorghis, Costas I.; Jones, Leighton; Priest, David-Lee; Akers, Rose I.; Clarke, Adam; Perry, Jennifer M.; Reddick, Benjamin T.; Bishop, Daniel T.; Lim, Harry B. T.

    2011-01-01

    In the present study, we investigated a hypothesized quartic relationship (meaning three inflection points) between exercise heart rate (HR) and preferred music tempo. Initial theoretical predictions suggested a positive linear relationship (Iwanaga, 1995a, 1995b); however, recent experimental work has shown that as exercise HR increases, step…

  5. Diagnostic Procedures for Detecting Nonlinear Relationships between Latent Variables

    ERIC Educational Resources Information Center

    Bauer, Daniel J.; Baldasaro, Ruth E.; Gottfredson, Nisha C.

    2012-01-01

    Structural equation models are commonly used to estimate relationships between latent variables. Almost universally, the fitted models specify that these relationships are linear in form. This assumption is rarely checked empirically, largely for lack of appropriate diagnostic techniques. This article presents and evaluates two procedures that can…

  6. Comprehensive Space-Object Characterization using Spectrally Compressive Polarimetric Sensing

    DTIC Science & Technology

    2015-04-08

    90o, 45o, and 135o polarization channels for lin- ear polarization state estimation. This linear polarimetry would satisfy several applications without...persive element. This technique eliminates mechanical movements that hinder conventional polarimetry . The experimental results show clear spatial

  7. Extant or Absent: Formation Water in New York State Drinking Water Wells

    NASA Astrophysics Data System (ADS)

    Christian, K.; Lautz, L. K.

    2013-12-01

    The current moratorium on hydraulic fracturing in New York State (NYS) provides an opportunity to collect baseline shallow groundwater quality data pre-hydraulic fracturing, which is essential for determining the natural variability of groundwater chemistry and to evaluate future claims of impaired groundwater quality if hydraulic fracturing occurs in the State. Concerns regarding the future environmental impact of shale gas extraction in NYS include potential shallow groundwater contamination due to migration of methane or formation water from shale gas extraction sites. Treatment, storage and disposal of saline flowback fluids after gas extraction could also be a source of water contamination. In this study, we combine southern NYS shallow groundwater chemistry data from Project Shale-Water Interaction Forensic Tools (SWIFT, n=60), the National Uranium Resource Evaluation program (NURE, n=684), and the USGS 305(b) Ambient Groundwater Quality Monitoring program (USGS, n=89) to examine evidence of formation water mixing with groundwater using the methodology of Warner et al. (2012). Groundwater characterized as low salinity (<20 mg/L Cl-) accounted for 72% of samples and 28% of samples had high salinity (>20 mg/L Cl-). A plot of bromide versus chloride shows high salinity groundwater samples with Br/Cl ratios >0.0001 fall on the mixing line between low salinity groundwater and Appalachian Basin formation water. Based on the observed linear relationship between bromide and chloride, it appears there is up to 1% formation water mixing with shallow groundwater in the region. The presence of formation water in shallow groundwater would indicate the existence of natural migratory pathways between deep formation wells and shallow groundwater aquifers. A plot of sodium versus chloride also illustrates a linear trend for Type D waters (R^2= 0.776), but the relationship is weaker than that for bromide versus chloride (R^2= 0.924). Similar linear relationships are not observed between other ions and chloride, including Mg, Ca, and Sr. If high salinity groundwater samples from NYS contain small percentages of formation water, we expect linear relationships between chloride and these other, generally conservative ions. The absence of these linear relationships suggests high salinity could be associated with contamination by landfill leachate, septic effluent, road salt, or other potential sources of elevated salt. Future work needs to determine if mixing of shallow groundwater with other potential sources of salinity, such as road deicers, can explain the observed linear relationships. Strontium isotopes from shallow groundwater samples will also be compared to those for NY formation water.

  8. Pattern Notes.

    ERIC Educational Resources Information Center

    Fields, Alan

    1980-01-01

    Looks at an alternative method to linear notes for organizing thoughts when preparing a talk or paper. This method displays the manner in which the relationships of a subject are organized and offers a format for displaying complex inter-dependencies in place of linear notes. (Author/MER)

  9. Study on a linear relationship between limited pressure difference and coil current of on/off valve and its influential factors.

    PubMed

    Zhang, Junzhi; Lv, Chen; Yue, Xiaowei; Li, Yutong; Yuan, Ye

    2014-01-01

    On/off solenoid valves with PWM control are widely used in all types of vehicle electro-hydraulic control systems respecting to their desirable properties of reliable, low cost and fast acting. However, it can hardly achieve a linear hydraulic modulation by using on/off valves mainly due to the nonlinear behaviors of valve dynamics and fluid, which affects the control accuracy significantly. In this paper, a linear relationship between limited pressure difference and coil current of an on/off valve in its critical closed state is proposed and illustrated, which has a great potential to be applied to improve hydraulic control performance. The hydraulic braking system of case study is modeled. The linear correspondence between limited pressure difference and coil current of the inlet valve is simulated and further verified experimentally. Based on validated simulation models, the impacts of key parameters are researched. The limited pressure difference affected by environmental temperatures is experimentally studied, and the amended linear relation is given according to the test data. © 2013 ISA. Published by Elsevier Ltd. All rights reserved.

  10. Cancer mortality-to-incidence ratio as an indicator of cancer management outcomes in Organization for Economic Cooperation and Development countries.

    PubMed

    Choi, Eunji; Lee, Sangeun; Nhung, Bui Cam; Suh, Mina; Park, Boyoung; Jun, Jae Kwan; Choi, Kui Son

    2017-01-01

    Assessing long-term success and efficiency is an essential part of evaluating cancer control programs. The mortality-to-incidence ratio (MIR) can serve as an insightful indicator of cancer management outcomes for individual nations. By calculating MIRs for the top five cancers in Organization for Economic Cooperation and Development (OECD) countries, the current study attempted to characterize the outcomes of national cancer management policies according to the health system ranking of each country. The MIRs for the five most burdensome cancers globally (lung, colorectal, prostate, stomach, and breast) were calculated for all 34 OECD countries using 2012 GLOBOCAN incidence and mortality statistics. Health system rankings reported by the World Health Organization in 2000 were updated with relevant information when possible. A linear regression model was created, using MIRs as the dependent variable and health system rankings as the independent variable. The linear relationships between MIRs and health system rankings for the five cancers were significant, with coefficients of determination ranging from 49 to 75% when outliers were excluded. A clear outlier, Korea reported lower-than-predicted MIRs for stomach and colorectal cancer, reflecting its strong national cancer control policies, especially cancer screening. The MIR was found to be a practical measure for evaluating the long-term success of cancer surveillance and the efficacy of cancer control programs, especially cancer screening. Extending the use of MIRs to evaluate other cancers may also prove useful.

  11. Generalized concentration addition: a method for examining mixtures containing partial agonists.

    PubMed

    Howard, Gregory J; Webster, Thomas F

    2009-08-07

    Environmentally relevant toxic exposures often consist of simultaneous exposure to multiple agents. Methods to predict the expected outcome of such combinations are critical both to risk assessment and to an accurate judgment of whether combinations are synergistic or antagonistic. Concentration addition (CA) has commonly been used to assess the presence of synergy or antagonism in combinations of similarly acting chemicals, and to predict effects of combinations of such agents. CA has the advantage of clear graphical interpretation: Curves of constant joint effect (isoboles) must be negatively sloped straight lines if the mixture is concentration additive. However, CA cannot be directly used to assess combinations that include partial agonists, although such agents are of considerable interest. Here, we propose a natural extension of CA to a functional form that may be applied to mixtures including full agonists and partial agonists. This extended definition, for which we suggest the term "generalized concentration addition," encompasses linear isoboles with slopes of any sign. We apply this approach to the simple example of agents with dose-response relationships described by Hill functions with slope parameter n=1. The resulting isoboles are in all cases linear, with negative, zero and positive slopes. Using simple mechanistic models of ligand-receptor systems, we show that the same isobole pattern and joint effects are generated by modeled combinations of full and partial agonists. Special cases include combinations of two full agonists and a full agonist plus a competitive antagonist.

  12. Facing haematopoietic stem-cell transplantation: do patients and their physicians agree regarding the prognosis?

    PubMed

    Grulke, Norbert; Bailer, Harald

    2010-10-01

    To evaluate the correlation and concordance between patients' and physicians' estimations of prognoses before initiation of the conditioning regimen for allogeneic haematopoietic stem-cell transplantation. A total of 123 patients and their attending physicians were asked to estimate a prognosis on a six-point scale. The patients were also asked to fill out questionnaires addressing their psychological state and coping. The mean prognostic estimations differed by 1.17 points (p<0.001), with the patients being more optimistic than the physicians. With respect to concordance: Pearson correlation r=0.024 (ns); unweighted kappa and kappa with linear weighting are 0.115 and 0.068, respectively. The prognostic estimates of the patients correlated with their psychological state, but not with the objective disease- or treatment-related variables, whereas the physicians' estimates were partially based on such objective factors. A clear significant association between actual survival and the physicians' estimates, but not the patients' estimates, was observed. If agreement regarding the prognosis exists, the relationship between physicians' and patients' estimates is probably non-linear. Assessing one's chances of being cured is a highly emotional task, and psychological processes such as denial or repression most likely play a decisive role. Moreover, collusion between the patient and physician may be inevitable in this situation. Whether it is desirable to gain concordance and who will benefit from such efforts must be discussed and empirically studied. Copyright © 2009 John Wiley & Sons, Ltd.

  13. [Relationship between finger dermatoglyphics and body size indicators in adulthood among Chinese twin population from Qingdao and Lishui cities].

    PubMed

    Sun, Luanluan; Yu, Canqing; Lyu, Jun; Cao, Weihua; Pang, Zengchang; Chen, Weijian; Wang, Shaojie; Chen, Rongfu; Gao, Wenjing; Li, Liming

    2014-01-01

    To study the correlation between fingerprints and body size indicators in adulthood. Samples were composed of twins from two sub-registries of Chinese National Twin Registry (CNTR), including 405 twin pairs in Lishui and 427 twin pairs in Qingdao. All participants were asked to complete the field survey, consisting of questionnaire, physical examination and blood collection. From the 832 twin pairs, those with complete and clear demographic prints were selected as the target population. Information of Fingerprints pixel on the demographic characteristics of these 100 twin pairs and their related adulthood body type indicators were finally chosen to form this research. Descriptive statistics and mixed linear model were used for data analyses. In the mixed linear models adjusted for age and sex, data showed that the body fat percentage of those who had arches was higher than those who did not have the arches (P = 0.002), and those who had radial loops would have higher body fat percentage when compared with ones who did not (P = 0.041). After adjusted for age, there appeared no statistically significant correlation between radial loops and systolic pressure, but the correlations of arches (P = 0.031)and radial loops (P = 0.022) to diastolic pressure still remained statistically significant. Statistically significant correlations were found between fingerprint types and body size indicators, and the fingerprint types showed a useful tool to explore the effects of uterine environment on health status in one's adulthood.

  14. Climate Cycles and Forecasts of Cutaneous Leishmaniasis, a Nonstationary Vector-Borne Disease

    PubMed Central

    Chaves, Luis Fernando; Pascual, Mercedes

    2006-01-01

    Background Cutaneous leishmaniasis (CL) is one of the main emergent diseases in the Americas. As in other vector-transmitted diseases, its transmission is sensitive to the physical environment, but no study has addressed the nonstationary nature of such relationships or the interannual patterns of cycling of the disease. Methods and Findings We studied monthly data, spanning from 1991 to 2001, of CL incidence in Costa Rica using several approaches for nonstationary time series analysis in order to ensure robustness in the description of CL's cycles. Interannual cycles of the disease and the association of these cycles to climate variables were described using frequency and time-frequency techniques for time series analysis. We fitted linear models to the data using climatic predictors, and tested forecasting accuracy for several intervals of time. Forecasts were evaluated using “out of fit” data (i.e., data not used to fit the models). We showed that CL has cycles of approximately 3 y that are coherent with those of temperature and El Niño Southern Oscillation indices (Sea Surface Temperature 4 and Multivariate ENSO Index). Conclusions Linear models using temperature and MEI can predict satisfactorily CL incidence dynamics up to 12 mo ahead, with an accuracy that varies from 72% to 77% depending on prediction time. They clearly outperform simpler models with no climate predictors, a finding that further supports a dynamical link between the disease and climate. PMID:16903778

  15. Fatty acid composition in native bees: Associations with thermal and feeding ecology.

    PubMed

    Giri, Susma; Rule, Daniel C; Dillon, Michael E

    2018-04-01

    Fatty acid (FA) composition of lipids plays a crucial role in the functioning of lipid-containing structures in organisms and may be affected by the temperature an organism experiences, as well as its diet. We compared FA composition among four bee genera: Andrena, Bombus, Megachile, and Osmia which differ in their thermal ecology and diet. Fatty acid methyl esters (FAME) were prepared by direct transesterification with KOH and analyzed using gas-liquid chromatography with a flame ionization detector. Sixteen total FAs ranging in chain length from eight to 22 carbon atoms were identified. Linear discriminant analysis separated the bees based on their FA composition. Andrena was characterized by relatively high concentrations of polyunsaturated FAs, Bombus by high monounsaturated FAs and Megachilids (Megachile and Osmia) by relatively high amounts of saturated FAs. These differences in FA composition may in part be explained by variation in the diets of these bees. Because tongue (proboscis) length may be used as a proxy for the types of flowers bees may visit for nectar and pollen, we compared FA composition among Bombus that differed in proboscis length (but have similar thermal ecology). A clear separation in FA composition within Bombus with varying proboscis lengths was found using linear discriminant analysis. Further, comparing the relationship between each genus by cluster analysis revealed aggregations by genus that were not completely separated, suggesting potential overlap in dietary acquisition of FAs. Copyright © 2018 Elsevier Inc. All rights reserved.

  16. Predicting musically induced emotions from physiological inputs: linear and neural network models.

    PubMed

    Russo, Frank A; Vempala, Naresh N; Sandstrom, Gillian M

    2013-01-01

    Listening to music often leads to physiological responses. Do these physiological responses contain sufficient information to infer emotion induced in the listener? The current study explores this question by attempting to predict judgments of "felt" emotion from physiological responses alone using linear and neural network models. We measured five channels of peripheral physiology from 20 participants-heart rate (HR), respiration, galvanic skin response, and activity in corrugator supercilii and zygomaticus major facial muscles. Using valence and arousal (VA) dimensions, participants rated their felt emotion after listening to each of 12 classical music excerpts. After extracting features from the five channels, we examined their correlation with VA ratings, and then performed multiple linear regression to see if a linear relationship between the physiological responses could account for the ratings. Although linear models predicted a significant amount of variance in arousal ratings, they were unable to do so with valence ratings. We then used a neural network to provide a non-linear account of the ratings. The network was trained on the mean ratings of eight of the 12 excerpts and tested on the remainder. Performance of the neural network confirms that physiological responses alone can be used to predict musically induced emotion. The non-linear model derived from the neural network was more accurate than linear models derived from multiple linear regression, particularly along the valence dimension. A secondary analysis allowed us to quantify the relative contributions of inputs to the non-linear model. The study represents a novel approach to understanding the complex relationship between physiological responses and musically induced emotion.

  17. A Resume of Stochastic, Time-Varying, Linear System Theory with Application to Active-Sonar Signal-Processing Problems

    DTIC Science & Technology

    1981-06-15

    relationships 5 3. Normalized energy in ambiguity function for i = 0 14 k ilI SACLANTCEN SR-50 A RESUME OF STOCHASTIC, TIME-VARYING, LINEAR SYSTEM THEORY WITH...the order in which systems are concatenated is unimportant. These results are exactly analogous to the results of time-invariant linear system theory in...REFERENCES 1. MEIER, L. A rdsum6 of deterministic time-varying linear system theory with application to active sonar signal processing problems, SACLANTCEN

  18. A Framework for Integrating Qualitative and Quantitative Data in Knowledge, Attitude, and Practice Studies: A Case Study of Pesticide Usage in Eastern Uganda

    PubMed Central

    Muleme, James; Kankya, Clovice; Ssempebwa, John C.; Mazeri, Stella; Muwonge, Adrian

    2017-01-01

    Knowledge, attitude, and practice (KAP) studies guide the implementation of public health interventions (PHIs), and they are important tools for political persuasion. The design and implementation of PHIs assumes a linear KAP relationship, i.e., an awareness campaign results in the desirable societal behavioral change. However, there is no robust framework for testing this relationship before and after PHIs. Here, we use qualitative and quantitative data on pesticide usage to test this linear relationship, identify associated context specific factors as well as assemble a framework that could be used to guide and evaluate PHIs. We used data from a cross-sectional mixed methods study on pesticide usage. Quantitative data were collected using a structured questionnaire from 167 households representing 1,002 individuals. Qualitative data were collected from key informants and focus group discussions. Quantitative and qualitative data analysis was done in R 3.2.0 as well as qualitative thematic analysis, respectively. Our framework shows that a KAP linear relationship only existed for households with a low knowledge score, suggesting that an awareness campaign would only be effective for ~37% of the households. Context specific socioeconomic factors explain why this relationship does not hold for households with high knowledge scores. These findings are essential for developing targeted cost-effective and sustainable interventions on pesticide usage and other PHIs with context specific modifications. PMID:29276703

  19. A Framework for Integrating Qualitative and Quantitative Data in Knowledge, Attitude, and Practice Studies: A Case Study of Pesticide Usage in Eastern Uganda.

    PubMed

    Muleme, James; Kankya, Clovice; Ssempebwa, John C; Mazeri, Stella; Muwonge, Adrian

    2017-01-01

    Knowledge, attitude, and practice (KAP) studies guide the implementation of public health interventions (PHIs), and they are important tools for political persuasion. The design and implementation of PHIs assumes a linear KAP relationship, i.e., an awareness campaign results in the desirable societal behavioral change. However, there is no robust framework for testing this relationship before and after PHIs. Here, we use qualitative and quantitative data on pesticide usage to test this linear relationship, identify associated context specific factors as well as assemble a framework that could be used to guide and evaluate PHIs. We used data from a cross-sectional mixed methods study on pesticide usage. Quantitative data were collected using a structured questionnaire from 167 households representing 1,002 individuals. Qualitative data were collected from key informants and focus group discussions. Quantitative and qualitative data analysis was done in R 3.2.0 as well as qualitative thematic analysis, respectively. Our framework shows that a KAP linear relationship only existed for households with a low knowledge score, suggesting that an awareness campaign would only be effective for ~37% of the households. Context specific socioeconomic factors explain why this relationship does not hold for households with high knowledge scores. These findings are essential for developing targeted cost-effective and sustainable interventions on pesticide usage and other PHIs with context specific modifications.

  20. Symbol-and-Arrow Diagrams in Teaching Pharmacokinetics.

    ERIC Educational Resources Information Center

    Hayton, William L.

    1990-01-01

    Symbol-and-arrow diagrams are helpful adjuncts to equations derived from pharmacokinetic models. Both show relationships among dependent and independent variables. Diagrams show only qualitative relationships, but clearly show which variables are dependent and which are independent, helping students understand complex but important functional…

  1. Evolutionary tree design: An exploratory study of the influence of linear versus branching format on visitors' interpretation and understanding across age groups

    NASA Astrophysics Data System (ADS)

    MacDonald, Teresa Elise

    This exploratory study sought to investigate the influence of tree graphic design---specifically linear versus branching depictions of taxa---on visitors in three different age groups (aged 11-13, 14-18, adults) interpretation and understanding using a multiple-case study strategy. The findings from this research indicate that linear and branched depictions elicit qualitatively different narratives and explanations about the relationships between the taxa in all age groups. Branched tree graphics support scientifically appropriate explanations of evolutionary relationships, i.e. that taxa are related via shared or common ancestry; while linear representations reinforce intuitive interpretations of ancestor-descendant or anagenic relationships. Furthermore, differences in the language used for linear and branched trees suggests that there is a spectrum within an analogy of developmental change that is thought to serve as a transitional concept between intuitive and scientific understanding--with 'evolved from' for branched depictions of taxa representing a shift towards an interpretation of shared ancestry rather than an individual transformation from one thing into another. In addition, branched graphics appear to support the correct reading and interpretation of shared or common ancestry in tree diagrams. Mixed reasoning was common and overall reasoning patterns were broadly similar among participants in all age groups, however, older youth (aged 14 to 18) and adults often provided more detail in their explanations and sometimes included references to evolutionary ideas such as variation, inheritance and selection.

  2. Resimulation of noise: a precision estimator for least square error curve-fitting tested for axial strain time constant imaging

    NASA Astrophysics Data System (ADS)

    Nair, S. P.; Righetti, R.

    2015-05-01

    Recent elastography techniques focus on imaging information on properties of materials which can be modeled as viscoelastic or poroelastic. These techniques often require the fitting of temporal strain data, acquired from either a creep or stress-relaxation experiment to a mathematical model using least square error (LSE) parameter estimation. It is known that the strain versus time relationships for tissues undergoing creep compression have a non-linear relationship. In non-linear cases, devising a measure of estimate reliability can be challenging. In this article, we have developed and tested a method to provide non linear LSE parameter estimate reliability: which we called Resimulation of Noise (RoN). RoN provides a measure of reliability by estimating the spread of parameter estimates from a single experiment realization. We have tested RoN specifically for the case of axial strain time constant parameter estimation in poroelastic media. Our tests show that the RoN estimated precision has a linear relationship to the actual precision of the LSE estimator. We have also compared results from the RoN derived measure of reliability against a commonly used reliability measure: the correlation coefficient (CorrCoeff). Our results show that CorrCoeff is a poor measure of estimate reliability for non-linear LSE parameter estimation. While the RoN is specifically tested only for axial strain time constant imaging, a general algorithm is provided for use in all LSE parameter estimation.

  3. Using spatial-stream-network models and long-term data to understand and predict dynamics of faecal contamination in a mixed land-use catchment.

    PubMed

    Neill, Aaron James; Tetzlaff, Doerthe; Strachan, Norval James Colin; Hough, Rupert Lloyd; Avery, Lisa Marie; Watson, Helen; Soulsby, Chris

    2018-01-15

    An 11year dataset of concentrations of E. coli at 10 spatially-distributed sites in a mixed land-use catchment in NE Scotland (52km 2 ) revealed that concentrations were not clearly associated with flow or season. The lack of a clear flow-concentration relationship may have been due to greater water fluxes from less-contaminated headwaters during high flows diluting downstream concentrations, the importance of persistent point sources of E. coli both anthropogenic and agricultural, and possibly the temporal resolution of the dataset. Point sources and year-round grazing of livestock probably obscured clear seasonality in concentrations. Multiple linear regression models identified potential for contamination by anthropogenic point sources as a significant predictor of long-term spatial patterns of low, average and high concentrations of E. coli. Neither arable nor pasture land was significant, even when accounting for hydrological connectivity with a topographic-index method. However, this may have reflected coarse-scale land-cover data inadequately representing "point sources" of agricultural contamination (e.g. direct defecation of livestock into the stream) and temporal changes in availability of E. coli from diffuse sources. Spatial-stream-network models (SSNMs) were applied in a novel context, and had value in making more robust catchment-scale predictions of concentrations of E. coli with estimates of uncertainty, and in enabling identification of potential "hot spots" of faecal contamination. Successfully managing faecal contamination of surface waters is vital for safeguarding public health. Our finding that concentrations of E. coli could not clearly be associated with flow or season may suggest that management strategies should not necessarily target only high flow events or summer when faecal contamination risk is often assumed to be greatest. Furthermore, we identified SSNMs as valuable tools for identifying possible "hot spots" of contamination which could be targeted for management, and for highlighting areas where additional monitoring could help better constrain predictions relating to faecal contamination. Copyright © 2017 Elsevier B.V. All rights reserved.

  4. Linearly polarized photoluminescence of InGaN quantum disks embedded in GaN nanorods.

    PubMed

    Park, Youngsin; Chan, Christopher C S; Nuttall, Luke; Puchtler, Tim J; Taylor, Robert A; Kim, Nammee; Jo, Yongcheol; Im, Hyunsik

    2018-05-25

    We have investigated the emission from InGaN/GaN quantum disks grown on the tip of GaN nanorods. The emission at 3.21 eV from the InGaN quantum disk doesn't show a Stark shift, and it is linearly polarized when excited perpendicular to the growth direction. The degree of linear polarization is about 39.3% due to the anisotropy of the nanostructures. In order to characterize a single nanostructure, the quantum disks were dispersed on a SiO 2 substrate patterned with a metal reference grid. By rotating the excitation polarization angle from parallel to perpendicular relative to the nanorods, the variation of overall PL for the 3.21 eV peak was recorded and it clearly showed the degree of linear polarization (DLP) of 51.5%.

  5. Enhanced linear photonic nanojet generated by core-shell optical microfibers

    NASA Astrophysics Data System (ADS)

    Liu, Cheng-Yang; Yen, Tzu-Ping; Chen, Chien-Wen

    2017-05-01

    The generation of linear photonic nanojet using core-shell optical microfiber is demonstrated numerically and experimentally in the visible light region. The power flow patterns for the core-shell optical microfiber are calculated by using the finite-difference time-domain method. The focusing properties of linear photonic nanojet are evaluated in terms of length and width along propagation and transversal directions. In experiment, the silica optical fiber is etched chemically down to 6 μm diameter and coated with metallic thin film by using glancing angle deposition. We show that the linear photonic nanojet is enhanced clearly by metallic shell due to surface plasmon polaritons. The large-area superresolution imaging can be performed by using a core-shell optical microfiber in the far-field system. The potential applications of this core-shell optical microfiber include micro-fluidics and nano-structure measurements.

  6. Cow milk consumption, insulin-like growth factor-I, and human biology: a life history approach.

    PubMed

    Wiley, Andrea S

    2012-01-01

    To assess the life history consequences of cow milk consumption at different stages in early life (prenatal to adolescence), especially with regard to linear growth and age at menarche and the role of insulin-like growth factor I (IGF-I) in mediating a relationship among milk, growth and development, and long-term biological outcomes. United States National Health and Nutrition Examination Survey (NHANES) data from 1999 to 2004 and review of existing literature. The literature tends to support milk's role in enhancing growth early in life (prior to age 5 years), but there is less support for this relationship during middle childhood. Milk has been associated with early menarche and with acceleration of linear growth in adolescence. NHANES data show a positive relationship between milk intake and linear growth in early childhood and adolescence, but not middle childhood, a period of relatively slow growth. IGF-I is a candidate bioactive molecule linking milk consumption to more rapid growth and development, although the mechanism by which it may exert such effects is unknown. Routine milk consumption is an evolutionarily novel dietary behavior that has the potential to alter human life history parameters, especially vis-à-vis linear growth, which in turn may have negative long-term biological consequences. Copyright © 2011 Wiley Periodicals, Inc.

  7. Do age and gender contribute to workers' burnout symptoms?

    PubMed

    Marchand, A; Blanc, M-E; Beauregard, N

    2018-06-15

    Despite mounting evidence on the association between work stress and burnout, there is limited knowledge about the extent to which workers' age and gender are associated with burnout. To evaluate the relationship between age, gender and their interaction with burnout in a sample of Canadian workers. Data were collected in 2009-12 from a sample of 2073 Canadian workers from 63 workplaces in the province of Quebec. Data were analysed with multilevel regression models to test for linear and non-linear relationships between age and burnout. Analyses adjusted for marital status, parental status, educational level and number of working hours were conducted on the total sample and stratified by gender. Data were collected from a sample of 2073 Canadian workers (response rate 73%). Age followed a non-linear relationship with emotional exhaustion and total burnout, while it was linearly related to cynicism and reduced professional efficacy. Burnout level reduced with increasing age in men, but the association was bimodal in women, with women aged between 20-35 and over 55 years showing the highest burnout level. These results suggest that burnout symptoms varied greatly according to different life stages of working men and women. Younger men, and women aged between 20-35 and 55 years and over are particularly susceptible and should be targeted for programmes to reduce risk of burnout.

  8. Are negative symptoms in schizophrenia a distinct therapeutic target?

    PubMed Central

    MICLUTIA, IOANA VALENTINA

    2018-01-01

    Background and aims The relationship between negative symptoms and cognition in schizophrenia is not clear, inconsistent findings have been reported by multiple authors and meta analyses. The aim of this study was to investigate the relationship between cognition and primary negative symptoms. Methods 67 outpatients diagnosed with schizophrenia were evaluated using PANSS and the NSA-16 scale. Correlation and regression analyses were used in the present study to investigate the relationship between the primary negative symptoms and cognition. Results No relationship was found between the PANSS Cognitive factor and Negative factor, but when investigating the relationship of the Cognitive PANSS factor with the negative symptoms evaluated with the NSA-16 scale, it was shown that there is a significant association between cognition and motor retardation. Conclusions Our study reveals the relative independence of cognitive factor from the global negative domain of the psychopathology, even though the association with motor retardation was clear. These findings also support the need of using appropriate assessment tools in order to gain a more refined understanding of the phenomenology of schizophrenia. PMID:29440953

  9. 76 FR 70206 - Self-Regulatory Organizations; ICE Clear Credit LLC; Notice of Filing of Proposed Rule Change to...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-10

    ... highly correlated relationship between long-short positions in CDS Indices and the underlying CDS Single... currently clear CDS Single Names for customer-related transactions. Accordingly, currently, there are no customer-related positions that would qualify for portfolio margining treatment. ICC does not believe that...

  10. Clear Communication in the Digital Age

    ERIC Educational Resources Information Center

    Manchester, Bette

    2009-01-01

    One of the essential factors of successful integration of technology in classrooms is the role and relationship of the technology coordinator in supporting integration efforts. The vision for the use of technology in each school and district and the leadership role of the tech coordinator must be clear and understood by all. This article presents…

  11. The earth's radiation budget and its relation to atmospheric hydrology. I - Observations of the clear sky greenhouse effect. II - Observations of cloud effects

    NASA Technical Reports Server (NTRS)

    Stephens, Graeme L.; Greenwald, Thomas J.

    1991-01-01

    The clear-sky components of the earth's radiation budget (ERB), the relationship of these components to the sea surface temperature (SST), and microwave-derived water-vapor amount are analyzed in an observational study along with the relationship between the cloudy-sky components of ERB and space/time coincident observations of SST, microwave-derived cloud liquid water, and cloud cover. The purpose of the study is to use these observations for establishing an understanding of the couplings between radiation and the atmosphere that are important to understanding climate feedback. A strategy for studying the greenhouse effect of earth by analyzing the emitted clear-sky longwave flux over the ocean is proposed. It is concluded that the largest observed influence of clouds on ERB is more consistent with macrophysical properties of clouds as opposed to microphysical properties. The analysis for clouds and the greenhouse effect of clouds is compared quantitatively with the clear sky results. Land-ocean differences and tropical-midlatitude differences are shown and explained in terms of the cloud macrostructure.

  12. Canopy-scale relationships between foliar nitrogen and albedo are not observed in leaf reflectance and transmittance within temperate deciduous tree species

    Treesearch

    Megan K. Bartlett; Scott V. Ollinger; David Y. Hollinger; Haley F. Wicklein; Andrew D. Richardson

    2011-01-01

    Strong positive correlations between the maximum rate of canopy photosynthesis, canopy-averaged foliar nitrogen concentration, and canopy albedo have been shown in previous studies. While leaf-level relationships between photosynthetic capacity and foliar nitrogen are well documented, it is not clear whether leaf-level relationships between solar-weighted reflectance...

  13. The relationship of intelligence and memory to interrogative suggestibility: the importance of range effects.

    PubMed

    Gudjonsson, G H

    1988-05-01

    This paper looks at the relationship between intelligence, memory and interrogative suggestibility, particularly with reference to range effects. The subjects were 60 normal subjects and 100 forensic patients who had completed the Gudjonsson Suggestibility Scale (GSS) and the Wechsler Adult Intelligence Scale. Clear range effects of IQ and memory were evident in their relationship with suggestibility.

  14. The Relationship between Body Esteem and Hope and Mental Health in Breast Cancer Patients after Mastectomy.

    PubMed

    Heidari, Mohammad; Ghodusi, Mansureh

    2015-01-01

    Breast cancer and its treatment, including mastectomy, can cause feelings of mutilation, depreciation in the value of the body, reduction in attractiveness, and lead to mental disorders and hopelessness. The present study aimed to determine the relationship between appreciating the body, hope and mental health in women with breast cancer after mastectomy. This study was a descriptive study of 100 breast cancer patients who had undergone mastectomy and referred to the Sayed Al-Shohada Medical Center in Isfahan, Iran. The subjects were selected by convenient sampling. Data gathering tools were the Body Esteem Scale (BES), Herth Hope Index (HHI), and Symptom Checklist 25 (SCL-25) mental health questionnaire. Data analysis was performed using SPSS software. Most of the patients had low body esteem. There was a significant direct linear relationship between body esteem and hope and mental health. This relationship was stronger between valuing the body and hope. Body esteem has a significant linear relationship with hope and mental health.

  15. Ideal Standards, Acceptance, and Relationship Satisfaction: Latitudes of Differential Effects

    PubMed Central

    Buyukcan-Tetik, Asuman; Campbell, Lorne; Finkenauer, Catrin; Karremans, Johan C.; Kappen, Gesa

    2017-01-01

    We examined whether the relations of consistency between ideal standards and perceptions of a current romantic partner with partner acceptance and relationship satisfaction level off, or decelerate, above a threshold. We tested our hypothesis using a 3-year longitudinal data set collected from heterosexual newlywed couples. We used two indicators of consistency: pattern correspondence (within-person correlation between ideal standards and perceived partner ratings) and mean-level match (difference between ideal standards score and perceived partner score). Our results revealed that pattern correspondence had no relation with partner acceptance, but a positive linear/exponential association with relationship satisfaction. Mean-level match had a significant positive association with actor’s acceptance and relationship satisfaction up to the point where perceived partner score equaled ideal standards score. Partner effects did not show a consistent pattern. The results suggest that the consistency between ideal standards and perceived partner attributes has a non-linear association with acceptance and relationship satisfaction, although the results were more conclusive for mean-level match. PMID:29033876

  16. Structural characterization and electrical conductivity of the Ca{sub 0.01}La{sub 0.99−x}Sm{sub x}NbO{sub 4−δ} solid series

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cao, Yong; Duan, Nanqi; Yan, Dong, E-mail: yand@hust.edu.cn

    Ca{sub 0.01}La{sub 0.99−x}Sm{sub x}NbO{sub 4−δ} (x=0, 0.1, 0.2, 0.4, 0.6, 0.8, 0.99) is prepared by using a solid reaction route, and single phase is achieved. Structural and phase transformation of Ca{sub 0.01}La{sub 0.99−x}Sm{sub x}NbO{sub 4−δ} have been characterized by high temperature X-ray diffraction. The lattice parameters a, b, c decrease and γ increases with increasing x, at both room and high temperature. The phase transformation temperature increases linearly with increasing x for Ca{sub 0.01}La{sub 0.99−x}Sm{sub x}NbO{sub 4−δ}. The electrical conductivity of Ca{sub 0.01}La{sub 0.99−x}Sm{sub x}NbO{sub 4−δ} is measured in wet air. A clear relationship between the structural, phase transformation andmore » electrical conductivity of Ca{sub 0.01}La{sub 0.99−x}Sm{sub x}NbO{sub 4−δ} is built, which will provide a guideline to tailor the electrical conductivity. - Graphical abstract: Structural and phase transformation of Ca{sub 0.01}La{sub 0.99−x}Sm{sub x}NbO{sub 4−δ} have been characterized by high temperature X-ray diffraction, as well as the conductivity of Ca{sub 0.01}La{sub 0.99−x}Sm{sub x}NbO{sub 4−δ} in wet air. A clear relationship between the structural, phase transformation and electrical conductivity of Ca{sub 0.01}La{sub 0.99−x}Sm{sub x}NbO{sub 4−δ} is built. - Highlights: • Ca{sub 0.01}La{sub 0.99−x}Sm{sub x}NbO{sub 4−δ} with various Sm contents was prepared. • Structure, phase transformation and electrical conductivity of Ca{sub 0.01}La{sub 0.99−x}Sm{sub x}NbO{sub 4−δ} were characterized. • A relationship between the structure, phase transformation and electrical conductivity was well established.« less

  17. Life satisfaction and age: Dealing with underidentification in age-period-cohort models.

    PubMed

    de Ree, Joppe; Alessie, Rob

    2011-07-01

    Recent literature typically finds a U shaped relationship between life satisfaction and age. Age profiles, however, are not identified without forcing arbitrary restrictions on the cohort and/or time profiles. In this paper we report what can be identified about the relationship between life satisfaction and age without applying such restrictions. Also, we identify the restrictions needed to conclude that life satisfaction is U shaped in age. For the case of Germany, we find that the relationship between life satisfaction and age is indeed U shaped, but only under the untestable condition that the linear time trend is negative and that the linear trend across birth cohorts is practically flat. Copyright © 2011 Elsevier Ltd. All rights reserved.

  18. Long-Term Coffee Consumption and Risk of Cardiovascular Disease: A Systematic Review and a Dose-Response Meta-Analysis of Prospective Cohort Studies

    PubMed Central

    Ding, Ming; Bhupathiraju, Shilpa N; Satija, Ambika; van Dam, Rob M; Hu, Frank B

    2013-01-01

    Background Considerable controversy exists regarding the association between coffee consumption and cardiovascular disease (CVD) risk. A meta-analysis was performed to assess the dose-response relationship of long-term coffee consumption with CVD risk. Methods and Results Pubmed and EMBASE were searched for prospective cohort studies of the relationship between coffee consumption and CVD risk, which included coronary heart disease, stroke, heart failure, and CVD mortality. Thirty-six studies were included with 1,279,804 participants and 36,352 CVD cases. A non-linear relationship of coffee consumption with CVD risk was identified (P for heterogeneity = 0.09, P for trend < 0.001, P for non-linearity < 0.001). Compared with the lowest category of coffee consumption (median: 0 cups/d), the relative risk of CVD was 0.95 (95% CI, 0.87 to 1.03) for the highest (median: 5 cups/d) category, 0.85 (0.80 to 0.90) for the second highest (median: 3.5 cups/d), and 0.89 (0.84 to 0.94) for the third highest category (median: 1.5 cups/d). Looking at separate outcomes, coffee consumption was non-linearly associated with both CHD (P for heterogeneity = 0.001, P for trend < 0.001, P for non-linearity < 0.001) and stroke risks (P for heterogeneity = 0.07, P for trend < 0.001, P for non-linearity< 0.001) (P for trend differences > 0.05). Conclusions A non-linear association between coffee consumption with CVD risk was observed in this meta-analysis. Moderate coffee consumption was inversely significantly associated with CVD risk, with the lowest CVD risk at 3 to 5 cups/d, and heavy coffee consumption was not associated with elevated CVD risk. PMID:24201300

  19. Different responses of weather factors on hand, foot and mouth disease in three different climate areas of Gansu, China.

    PubMed

    Gou, Faxiang; Liu, Xinfeng; He, Jian; Liu, Dongpeng; Cheng, Yao; Liu, Haixia; Yang, Xiaoting; Wei, Kongfu; Zheng, Yunhe; Jiang, Xiaojuan; Meng, Lei; Hu, Wenbiao

    2018-01-08

    To determine the linear and non-linear interacting relationships between weather factors and hand, foot and mouth disease (HFMD) in children in Gansu, China, and gain further traction as an early warning signal based on weather variability for HFMD transmission. Weekly HFMD cases aged less than 15 and meteorological information from 2010 to 2014 in Jiuquan, Lanzhou and Tianshu, Gansu, China were collected. Generalized linear regression models (GLM) with Poisson link and classification and regression trees (CART) were employed to determine the combined and interactive relationship of weather factors and HFMD in both linear and non-linear ways. GLM suggested an increase in weekly HFMD of 5.9% [95% confidence interval (CI): 5.4%, 6.5%] in Tianshui, 2.8% [2.5%, 3.1%] in Lanzhou and 1.8% [1.4%, 2.2%] in Jiuquan in association with a 1 °C increase in average temperature, respectively. And 1% increase of relative humidity could increase weekly HFMD of 2.47% [2.23%, 2.71%] in Lanzhou and 1.11% [0.72%, 1.51%] in Tianshui. CART revealed that average temperature and relative humidity were the first two important determinants, and their threshold values for average temperature deceased from 20 °C of Jiuquan to 16 °C in Tianshui; and for relative humidity, threshold values increased from 38% of Jiuquan to 65% of Tianshui. Average temperature was the primary weather factor in three areas, more sensitive in southeast Tianshui, compared with northwest Jiuquan; Relative humidity's effect on HFMD showed a non-linear interacting relationship with average temperature.

  20. Local muscle oxygen consumption related to external and joint specific power.

    PubMed

    Skovereng, Knut; Ettema, Gertjan; van Beekvelt, Mireille

    2016-02-01

    The purpose of the present study was to examine the effects of external work rate on joint specific power and the relationship between knee extension power and vastus lateralis muscle oxygen consumption (mVO2). We measured kinematics and pedal forces and used inverse dynamics to calculate joint power for the hip, knee and ankle joints during an incremental cycling protocol performed by 21 recreational cyclists. Vastus lateralis mVO2 was estimated using near-infrared spectroscopy with an arterial occlusion. The main finding was a non-linear relationship between vastus lateralis mVO2 and external work rate that was characterised by an increase followed by a tendency for a levelling off (R(2)=0.99 and 0.94 for the quadratic and linear models respectively, p<0.05). When comparing 100W and 225W, there was a ∼43W increase in knee extension but still a ∼9% decrease in relative contribution of knee extension to external work rate resulting from a ∼47W increase in hip extension. When vastus lateralis mVO2 was related to knee extension power, the relationship was still non-linear (R(2)=0.99 and 0.97 for the quadratic and linear models respectively, p<0.05). These results demonstrate a non-linear response in mVO2 relative to a change in external work rate. Relating vastus lateralis mVO2 to knee extension power showed a better fit to a linear equation compared to external work rate, but it is not a straight line. Copyright © 2015 The Authors. Published by Elsevier B.V. All rights reserved.

  1. The Impact of Marketing Actions on Relationship Quality in the Higher Education Sector in Jordan

    ERIC Educational Resources Information Center

    Al-Alak, Basheer A. M.

    2006-01-01

    This field/analytical study examined the marketing actions (antecedents) and performance (consequences) of relationship quality in a higher education setting. To analyze data collected from a random sample of 271 undergraduate students at AL-Zaytoonah Private University of Jordan, the linear structural relationship (LISREL) model was used to…

  2. DSPCP: A Data Scalable Approach for Identifying Relationships in Parallel Coordinates.

    PubMed

    Nguyen, Hoa; Rosen, Paul

    2018-03-01

    Parallel coordinates plots (PCPs) are a well-studied technique for exploring multi-attribute datasets. In many situations, users find them a flexible method to analyze and interact with data. Unfortunately, using PCPs becomes challenging as the number of data items grows large or multiple trends within the data mix in the visualization. The resulting overdraw can obscure important features. A number of modifications to PCPs have been proposed, including using color, opacity, smooth curves, frequency, density, and animation to mitigate this problem. However, these modified PCPs tend to have their own limitations in the kinds of relationships they emphasize. We propose a new data scalable design for representing and exploring data relationships in PCPs. The approach exploits the point/line duality property of PCPs and a local linear assumption of data to extract and represent relationship summarizations. This approach simultaneously shows relationships in the data and the consistency of those relationships. Our approach supports various visualization tasks, including mixed linear and nonlinear pattern identification, noise detection, and outlier detection, all in large data. We demonstrate these tasks on multiple synthetic and real-world datasets.

  3. Relationship between head posture and dentofacial morphology in patients with TMJ osteoarthritis/osteoarthrosis.

    PubMed

    Ioi, Hideki; Matsumoto, Ryusuke; Nishioka, Masato; Goto, Tazuko K; Nakata, Shunsuke; Nakasima, Akihiko; Counts, Amy L

    2008-01-01

    To test whether there is a relationship between head and cervical posture and dentofacial morphology in patients with temporomandibular joint osteoarthritis/osteoarthrosis (OA). The subjects consisted of 34 Japanese females with TMJ OA (aged 24.7 +/- 6.1 years). Six craniocervical angular measurements were constructed for head posture. Two angular and 6 linear measurements were constructed for the skeletal relationship, while 1 angular and 6 linear measurements were constructed for the dental relationship. Pearson correlation coefficients were calculated between head posture and dentofacial variables. In the skeletal relationship, increased craniocervical angulations were significantly associated with a more posterior position of the maxilla, a decreased Frankfort to mandibular plane angle, decreased mandibular length, and a decreased lower facial height. In the dental relationship, increased craniocervical angulations were significantly associated with more posterior positions of the anterior teeth to the basal bone and decreased alveolar height of the anterior-posterior teeth. The hypothesis was rejected. These results suggest that an association may exist between head and cervical posture and dentofacial morphology in patients with TMJ OA.

  4. Moral Values Congruence and Miners' Policy Following Behavior: The Role of Supervisor Morality.

    PubMed

    Lu, Hui; Chen, Hong; Du, Wei; Long, Ruyin

    2017-06-01

    Ethical culture construction is beneficial to maximize policy following behavior (PFB) and avoid accidents of coal miners in an economic downturn. This paper examines the congruence between coal mine ethical culture values (ECVs) and miners' moral values (MVs) and the relationship with PFB. To shed light on this relationship, supervisor moral values (SMVs) act as a key moderator. We build on the initial structure of values to measure ECVs, MVs, and SMVs. At the same time, available congruence was defined to describe the relationship between the two values. Drawing upon a survey of 267 miners in Chinese large state-owned coal mining enterprises, results revealed that ECVs-MVs congruence had a linear relationship with intrinsic PFB (IPFB) and a non-linear relationship with extrinsic PFB. These findings demonstrate that SMVs had a moderating effect on the relationship between ECVs-MVs congruence and extrinsic PFB. Thus, we continued to calculate the available congruence scope in tested enterprises. Furthermore, this study gives relative management proposals and suggestions to improve miners' moral standards and to reduce coal mine accidents.

  5. Non-linear associations between laryngo-pharyngeal symptoms of gastro-oesophageal reflux disease: clues from artificial intelligence analysis

    PubMed Central

    Grossi, E

    2006-01-01

    Summary The relationship between the different symptoms of gastro-oesophageal reflux disease remain markedly obscure due to the high underlying non-linearity and the lack of studies focusing on the problem. Aim of this study was to evaluate the hidden relationships between the triad of symptoms related to gastro-oesophageal reflux disease using advanced mathematical techniques, borrowed from the artificial intelligence field, in a cohort of patients with oesophagitis. A total of 388 patients (from 60 centres) with endoscopic evidence of oesophagitis were recruited. The severity of oesophagitis was scored by means of the Savary-Miller classification. PST algorithm was employed. This study shows that laryngo-pharyngeal symptoms related to gastro-oesophageal reflux disease are correlated even if in a non-linear way. PMID:17345935

  6. Non-linear associations between laryngo-pharyngeal symptoms of gastro-oesophageal reflux disease: clues from artificial intelligence analysis.

    PubMed

    Grossi, E

    2006-10-01

    The relationship between the different symptoms of gastro-oesophageal reflux disease remain markedly obscure due to the high underlying non-linearity and the lack of studies focusing on the problem. Aim of this study was to evaluate the hidden relationships between the triad of symptoms related to gastro-oesophageal reflux disease using advanced mathematical techniques, borrowed from the artificial intelligence field, in a cohort of patients with oesophagitis. A total of 388 patients (from 60 centres) with endoscopic evidence of oesophagitis were recruited. The severity of oesophagitis was scored by means of the Savary-Miller classification. PST algorithm was employed. This study shows that laryngo-pharyngeal symptoms related to gastro-oesophageal reflux disease are correlated even if in a non-linear way.

  7. Maturation of cortical auditory evoked potentials (CAEPs) to speech recorded from frontocentral and temporal sites: three months to eight years of age.

    PubMed

    Shafer, Valerie L; Yu, Yan H; Wagner, Monica

    2015-02-01

    The goal of the current analysis was to examine the maturation of cortical auditory evoked potentials (CAEPs) from three months of age to eight years of age. The superior frontal positive-negative-positive sequence (P1, N2, P2) and the temporal site, negative-positive-negative sequence (possibly, Na, Ta, Tb of the T-complex) were examined. Event-related potentials were recorded from 63 scalp sites to a 250-ms vowel. Amplitude and latency of peaks were measured at left and right frontal sites (near Fz) and at left and right temporal sites (T7 and T8). In addition, the largest peak (typically corresponding to P1) was selected from global field power (GFP). The results revealed a large positive peak (P1) easily identified at frontal sites across all ages. The N2 emerged after 6 months of age and the following P2 between 8 and 30 months of age. The latencies of these peaks decreased exponentially with the most rapid decrease observed for P1. For amplitude, only P1 showed a clear relationship with age, becoming more positive in a somewhat linear fashion. At the temporal sites only a negative peak, which might be Na, was clearly observed at both left and right sites in children older than 14 months and peaking between 100 and 200 ms. P1 measures at frontal sites and Na peak latencies were moderately correlated. The temporal negative peak latency showed a different maturational timecourse (linear in nature) than the P1 peak, suggesting at least partial independence. Distinct Ta (positive) and Tb (negative) peaks, following Na and peaking between 120 and 220 ms were not consistently found in most age groups of children, except Ta which was present in 7 year olds. Future research, which includes manipulation of stimulus factors, and use of modeling techniques will be needed to explain the apparent, protracted maturation of the temporal site measures in the current study. Copyright © 2014 Elsevier B.V. All rights reserved.

  8. General relationships between ultrasonic attenuation and dispersion

    NASA Technical Reports Server (NTRS)

    Odonnell, M.; Jaynes, E. T.; Miller, J. G.

    1978-01-01

    General relationships between the ultrasonic attenuation and dispersion are presented. The validity of these nonlocal relationships hinges only on the properties of causality and linearity, and does not depend upon details of the mechanism responsible for the attenuation and dispersion. Approximate, nearly local relationships are presented and are demonstrated to predict accurately the ultrasonic dispersion in solutions of hemoglobin from the results of attenuation measurements.

  9. Microstructural evolution during reheating of A356 machining chips at semisolid state

    NASA Astrophysics Data System (ADS)

    Wang, Fang; Zhang, Wen-qiang; Xiao, Wen-long; Yamagata, Hiroshi; Ma, Chao-li

    2017-08-01

    The microstructural evolution of A356 machining chips in the semisolid state was studied at different temperatures and holding times. The results showed that the elongated α-Al grains first recrystallized in the semisolid state and then became globular with a high shape factor (SF). Both the temperature and the holding time clearly affected the grain size and SF. When the heating temperature or holding time was increased, the grain size and SF gradually increased and finally became stable. Moreover, the Vickers hardness of primary α-Al grains gradually decreased with increasing heating temperature. The optimal slurry for semisolid processing, with a good combination of grain size and SF, was obtained when the chips were held at 600°C for 15 min. The semisolid slurry of A356 chips exhibited a lower coarsening rate of α-Al grains than those produced by most of the conventional semisolid processes. The coarsening coefficient was determined to be 436 μm3·s-1 on the basis of the linear Lifshitz-Slyozov-Wagner (LSW) relationship.

  10. A porous media theory for characterization of membrane blood oxygenation devices

    NASA Astrophysics Data System (ADS)

    Sano, Yoshihiko; Adachi, Jun; Nakayama, Akira

    2013-07-01

    A porous media theory has been proposed to characterize oxygen transport processes associated with membrane blood oxygenation devices. For the first time, a rigorous mathematical procedure based a volume averaging procedure has been presented to derive a complete set of the governing equations for the blood flow field and oxygen concentration field. As a first step towards a complete three-dimensional numerical analysis, one-dimensional steady case is considered to model typical membrane blood oxygenator scenarios, and to validate the derived equations. The relative magnitudes of oxygen transport terms are made clear, introducing a dimensionless parameter which measures the distance the oxygen gas travels to dissolve in the blood as compared with the blood dispersion length. This dimensionless number is found so large that the oxygen diffusion term can be neglected in most cases. A simple linear relationship between the blood flow rate and total oxygen transfer rate is found for oxygenators with sufficiently large membrane surface areas. Comparison of the one-dimensional analytic results and available experimental data reveals the soundness of the present analysis.

  11. Acute toxicity assessment of perfluorinated carboxylic acids towards the Baltic microalgae.

    PubMed

    Latała, Adam; Nędzi, Marcin; Stepnowski, Piotr

    2009-09-01

    The presence of high-energy carbon-fluorine bonds in perfluoro compounds lends them great stability and causes them to be environmentally persistent. Relatively little is known about the acute toxicity of perfluorinated carboxylic acids (PFCAs) to ecotoxicological markers such as aquatic plants and animals. This study tested the toxicity of these compounds to the green alga Chlorella vulgaris, the diatom Skeletonema marinoi and the blue-green alga Geitlerinema amphibium, which are species representative of the algal flora of the Baltic Sea. The EC(50) values obtained range from 0.28 mM to 12.84 mM. A distinct relationship between hydrophobicity and toxicity is demonstrated. For every extra perfluoromethylene group in the alkyl chain, the toxicity increases twofold. LogEC(50) values are very well correlated linearly with both the number of carbon atoms in the perfluoroalkyl chain and the partition coefficients. The results also indicate that there are clear differences between the responses of particular taxonomic groups of algae: blue-green algae and diatoms are far more sensitive to PFCAs than green algae, probably because of differences in cell wall structure.

  12. Automated coronal hole identification via multi-thermal intensity segmentation

    NASA Astrophysics Data System (ADS)

    Garton, Tadhg M.; Gallagher, Peter T.; Murray, Sophie A.

    2018-01-01

    Coronal holes (CH) are regions of open magnetic fields that appear as dark areas in the solar corona due to their low density and temperature compared to the surrounding quiet corona. To date, accurate identification and segmentation of CHs has been a difficult task due to their comparable intensity to local quiet Sun regions. Current segmentation methods typically rely on the use of single Extreme Ultra-Violet passband and magnetogram images to extract CH information. Here, the coronal hole identification via multi-thermal emission recognition algorithm (CHIMERA) is described, which analyses multi-thermal images from the atmospheric image assembly (AIA) onboard the solar dynamics observatory (SDO) to segment coronal hole boundaries by their intensity ratio across three passbands (171 Å, 193 Å, and 211 Å). The algorithm allows accurate extraction of CH boundaries and many of their properties, such as area, position, latitudinal and longitudinal width, and magnetic polarity of segmented CHs. From these properties, a clear linear relationship was identified between the duration of geomagnetic storms and coronal hole areas. CHIMERA can therefore form the basis of more accurate forecasting of the start and duration of geomagnetic storms.

  13. A theoretical investigation of one-dimensional lithium-bonded chain: enhanced first hyperpolarizability and little red-shift.

    PubMed

    Ma, Fang; Bai, Dongsheng; Xu, Hongliang

    2014-12-01

    We present a theoretical investigation of the electric properties of two kinds of one-dimensional lithium bonded chains: (NC-Li)n and (NC-CC-Li)n (n = 1-8). The resulting (NC-Li)n and (NC-CC-Li)n were found to exhibit enhanced first hyperpolarizabilities (β 0) with increasing n, and a slight change in the absorption maximum wavelength λmax at the crucial transition. Comparing with (NC-Li)n, (NC-CC-Li)n exhibited particularly drastically enhanced β 0 values due to clearly enhanced coupled oscillators and double-degenerated charge transitions. β 0 is known to be the microscopic origin of the second-order non-linear optical (NLO) property, and λmax is an approximate measure of the transparency achievable, thus both are important indices of high-performance NLO molecules. Therefore, our investigations into one-dimensional lithium bond chains will be beneficial to understanding the relationship between β 0 and λmax, thus aiding the design of one-dimensional NLO materials with excellent transparence-efficiency.

  14. Effects of anaerobic digestion on chlortetracycline and oxytetracycline degradation efficiency for swine manure.

    PubMed

    Yin, Fubin; Dong, Hongmin; Ji, Chao; Tao, Xiuping; Chen, Yongxing

    2016-10-01

    Manure containing antibiotics is considered a hazardous substance that poses a serious health risk to the environment and to human health. Anaerobic digestion (AD) could not only treatment animal waste but also generate valuable biogas. However, the interaction between antibiotics in manure and the AD process has not been clearly understood. In this study, experiments on biochemical methane potential (BMP) were conducted to determine the inhibition of the AD process from antibiotics and the threshold of complete antibiotic removal. The thresholds of the complete antibiotic removal were 60 and 40mg/kg·TS for CTC and OTC, respectively. CTC and OTC with concentrations below thresholds could increase the BMP of manure. When the CTC and OTC concentrations exceeded the thresholds, they inhibited manure fermentation, and the CTC removal rate declined exponentially with concentration (60-500mg/kg·TS). The relationship between OTC antibiotic concentration and its removal rate in AD treatment was described with exponential (40-100mg/kg·TS) and linear equations (100-500mg/kg·TS). Copyright © 2016 Elsevier Ltd. All rights reserved.

  15. How social opinion influences syntactic processing—An investigation using virtual reality

    PubMed Central

    Hagoort, Peter; Segaert, Katrien

    2017-01-01

    The extent to which you adapt your grammatical choices to match that of your interlocutor’s (structural priming) can be influenced by the social opinion you have of your interlocutor. However, the direction and reliability of this effect is unclear as different studies have reported seemingly contradictory results. We have operationalized social perception as the ratings of strangeness for different avatars in a virtual reality study. The use of avatars ensured maximal control over the interlocutor’s behaviour and a clear dimension along which to manipulate social perceptions toward this interlocutor. Our results suggest an inverted U-shaped curve in structural priming magnitude for passives as a function of strangeness: the participants showed the largest priming effects for the intermediately strange, with a decrease when interacting with the least- or most-strange avatars. The relationship between social perception and priming magnitude may thus be non-linear. There seems to be a 'happy medium' in strangeness, evoking the largest priming effect. We did not find a significant interaction of priming magnitude with any social perception. PMID:28384163

  16. Characteristics of trophic transfer of polychlorinated biphenyls in marine organisms in Incheon North Harbor, Korea.

    PubMed

    Kim, Seung Kyu; Lee, Dong Soo; Oh, Jae Ryong

    2002-04-01

    The trophic transfer of polychlorinated biphenyls (PCBs) was characterized for zooplankton (primarily Paracalanus spp. and Acartia spp.), pacific oyster (Crassostrea gigas), shore crab (Hemigrapsus penicillatus), and goby (Acanthogobius hasta) in the aquatic system of Incheon North Harbor, Korea. The congener pattern in the species was clearly divided by the main PCB uptake route. Compared with zooplankton and oyster, the fraction of heavier homologues increased in crab and goby that take PCBs from food. Linear relationships were observed between log (fugacity in lipid/fugacity in seawater) and log Kow for all the species. For zooplankton and oyster, such an observation should not be regarded as a true absence of superhydrophobicity, because establishment of equilibrium with seawater was not evident. For crab and goby, the absence of superhydrophobicity was evidenced by the trophic transfer factor that continuously increased with Kow up to 10(7.8). These results suggest that superhydrophobicity might be species specific. The trophic transfer factors and the fugacity levels in the lipid phase indicated that bioaccumulation in crab and goby advanced beyond the level in equilibrium with seawater in the harbor basin.

  17. Fluorescent x-ray computed tomography to visualize specific material distribution

    NASA Astrophysics Data System (ADS)

    Takeda, Tohoru; Yuasa, Tetsuya; Hoshino, Atsunori; Akiba, Masahiro; Uchida, Akira; Kazama, Masahiro; Hyodo, Kazuyuki; Dilmanian, F. Avraham; Akatsuka, Takao; Itai, Yuji

    1997-10-01

    Fluorescent x-ray computed tomography (FXCT) is being developed to detect non-radioactive contrast materials in living specimens. The FXCT systems consists of a silicon channel cut monochromator, an x-ray slit and a collimator for detection, a scanning table for the target organ and an x-ray detector for fluorescent x-ray and transmission x-ray. To reduce Compton scattering overlapped on the K(alpha) line, incident monochromatic x-ray was set at 37 keV. At 37 keV Monte Carlo simulation showed almost complete separation between Compton scattering and the K(alpha) line. Actual experiments revealed small contamination of Compton scattering on the K(alpha) line. A clear FXCT image of a phantom was obtained. Using this system the minimal detectable dose of iodine was 30 ng in a volume of 1 mm3, and a linear relationship was demonstrated between photon counts of fluorescent x-rays and the concentration of iodine contrast material. The use of high incident x-ray energy allows an increase in the signal to noise ratio by reducing the Compton scattering on the K(alpha) line.

  18. Telomere length maintenance--an ALTernative mechanism.

    PubMed

    Royle, N J; Foxon, J; Jeyapalan, J N; Mendez-Bermudez, A; Novo, C L; Williams, J; Cotton, V E

    2008-01-01

    The Alternative Lengthening of Telomeres (ALT) mechanism is utilised by approximately 10% of human tumours and a higher proportion of some types of sarcomas. ALT+ cell lines and tumours show heterogeneous telomere length, extra-chromosomal circular and linear telomeric DNA, ALT associated promyelocytic bodies (APBs), a high frequency of post-replication exchanges in telomeres (designated as telomere-sister chromatid exchanges, T-SCE) and high instability at a GC-rich minisatellite, MS32 (D1S8). It is clear that there is a link between the minisatellite instability and the mechanism that underpins ALT, however currently the nature of this relationship is uncertain. Single molecule analysis of telomeric DNA from ALT+ cell lines and tumours has revealed complex telomere mutations that have not been seen in cell lines or tumours that express telomerase. These complex telomere mutations cannot be explained by T-SCE but must arise by another inter-molecular process. The break-induced replication (BIR) model that may explain the observed high frequency of T-SCE and the presence of complex telomere mutations is reviewed. Copyright 2008 S. Karger AG, Basel.

  19. Linear relationships between shoot magnesium and calcium concentrations among angiosperm species are associated with cell wall chemistry.

    PubMed

    White, Philip J; Broadley, Martin R; El-Serehy, Hamed A; George, Timothy S; Neugebauer, Konrad

    2018-05-02

    Linear relationships are commonly observed between shoot magnesium ([Mg]shoot) and shoot calcium ([Ca]shoot) concentrations among angiosperm species growing in the same environment. This article argues that, in plants that do not exhibit 'luxury' accumulation of Mg or Ca, (1) distinct stoichiometric relationships between [Mg]shoot and [Ca]shoot are exhibited by at least three groups of angiosperm species, namely commelinid monocots, eudicots excluding Caryophyllales, and Caryophyllales species; (2) these relationships are determined by cell wall chemistry and the Mg/Ca mass quotients in their cell walls; (3) differences between species in [Mg]shoot and [Ca]shoot within each group are associated with differences in the cation exchange capacity (CEC) of the cell walls of different species; and (4) Caryophyllales constitutively accumulate more Mg in their vacuoles than other angiosperm species when grown without a supra-sufficient Mg supply.

  20. Effects of fatigue on motor unit firing rate versus recruitment threshold relationships.

    PubMed

    Stock, Matt S; Beck, Travis W; Defreitas, Jason M

    2012-01-01

    The purpose of this study was to examine the influence of fatigue on the average firing rate versus recruitment threshold relationships for the vastus lateralis (VL) and vastus medialis. Nineteen subjects performed ten maximum voluntary contractions of the dominant leg extensors. Before and after this fatiguing protocol, the subjects performed a trapezoid isometric muscle action of the leg extensors, and bipolar surface electromyographic signals were detected from both muscles. These signals were then decomposed into individual motor unit action potential trains. For each subject and muscle, the relationship between average firing rate and recruitment threshold was examined using linear regression analyses. For the VL, the linear slope coefficients and y-intercepts for these relationships increased and decreased, respectively, after fatigue. For both muscles, many of the motor units decreased their firing rates. With fatigue, recruitment of higher threshold motor units resulted in an increase in slope for the VL. Copyright © 2011 Wiley Periodicals, Inc.

  1. Association between pulmonary function and renal function: findings from China and Australia.

    PubMed

    Yu, Dahai; Chen, Tao; Cai, Yamei; Zhao, Zhanzheng; Simmons, David

    2017-05-01

    The relationship between obstructive lung function and impaired renal function is unclear. This study investigated the dose-response relationship between obstructive lung function and impaired renal function. Two independent cross-sectional studies with representative sampling were applied. 1454 adults from rural Victoria, Australia (1298 with normal renal function, 156 with impaired renal function) and 5824 adults from Nanjing, China (4313 with normal renal function, 1511 with impaired renal function). Pulmonary function measurements included forced expiratory volume in one second (FEV1) and forced vital capacity (FVC). Estimated glomerular filtration rate (eGFR), and impaired renal function marked by eGFR <60 mL/min/1.73m 2 were used as outcome. eGFR increased linearly with FEV1 in Chinese participants and with FVC in Australians. A non-linear relationship with peaked eGFR was found for FEV1 at 2.65 L among Australians and for FVC at 2.78 L among Chinese participants, respectively. A non-linear relationship with peaked eGFR was found for the predicted percentage value of forced expiratory volume in 1 s (PFEV1) at 81-82% and for the predicted percentage value of forced vital capacity (PFVC) at 83-84% among both Chinese and Australian participants, respectively. The non-linear dose-response relationships between lung capacity measurements (both for FEV1 and FVC) and risk of impaired renal function were consistently identified in both Chinese and Australian participants. An increased risk of impaired renal function was found below 3.05 L both for FEV1 and FVC, respectively. The non-linear relationship between PFEV and PVC and the risk of impaired renal function were consistently identified in both Chinese and Australian participants. An increased risk of impaired renal function was found below 76-77% for PFEV1 and 79-80% for PFVC, respectively. In both Australian and Chinese populations, the risk of impaired renal function increased both with FEV1 and FVC below 3.05 L, with PFEV1 below 76-77% or with PFVC below 79-80%, respectively. Obstructive lung function was associated with increased risk of reduced renal function. The screen for impaired renal function in patients with obstructive lung disease might be useful to ensure there was no impaired renal function before the commencement of potentially nephrotoxic medication where indicated (eg diuretics).

  2. Relationships and Authentic Collaboration: Perceptions of a Building Leadership Team

    ERIC Educational Resources Information Center

    Conner, Tonya

    2015-01-01

    This research examined perceptions of a Building Leadership Team (BLT) regarding the school climate, collegial relationships, camaraderie, and team-building skills among certified faculty. Participants' perceptions changed from resistance accession once a clear understanding of authentic collaboration developed through five job-embedded…

  3. Generating Linear Equations Based on Quantitative Reasoning

    ERIC Educational Resources Information Center

    Lee, Mi Yeon

    2017-01-01

    The Common Core's Standards for Mathematical Practice encourage teachers to develop their students' ability to reason abstractly and quantitatively by helping students make sense of quantities and their relationships within problem situations. The seventh-grade content standards include objectives pertaining to developing linear equations in…

  4. Assessing the Liquidity of Firms: Robust Neural Network Regression as an Alternative to the Current Ratio

    NASA Astrophysics Data System (ADS)

    de Andrés, Javier; Landajo, Manuel; Lorca, Pedro; Labra, Jose; Ordóñez, Patricia

    Artificial neural networks have proven to be useful tools for solving financial analysis problems such as financial distress prediction and audit risk assessment. In this paper we focus on the performance of robust (least absolute deviation-based) neural networks on measuring liquidity of firms. The problem of learning the bivariate relationship between the components (namely, current liabilities and current assets) of the so-called current ratio is analyzed, and the predictive performance of several modelling paradigms (namely, linear and log-linear regressions, classical ratios and neural networks) is compared. An empirical analysis is conducted on a representative data base from the Spanish economy. Results indicate that classical ratio models are largely inadequate as a realistic description of the studied relationship, especially when used for predictive purposes. In a number of cases, especially when the analyzed firms are microenterprises, the linear specification is improved by considering the flexible non-linear structures provided by neural networks.

  5. Relationship of Productivity to Species Richness in the Xinjiang Temperate Grassland

    PubMed Central

    2016-01-01

    The relationship between species richness (SR) and aboveground net primary productivity (ANPP) is still a central and debated issue in community ecology. Previous studies have often emphasized the relationship of alpha diversity (number of species identity) to the mean ANPP with respect to the SR-ANPP relationship while neglecting the contribution of beta diversity (dissimilarity in species composition) to the mean ANPP and to the stability of ANPP (coefficient of ANPP: CV of ANPP). In this study, we used alpha and beta diversity, mean ANPP and the CV of ANPP collected from 159 sites and belonging to three vegetation types in the Xinjiang temperate grassland to first examine their trends along climatic factors and among different vegetation types and then test the relationship among alpha (beta) diversity and mean ANPP and the CV of ANPP. Our results showed that in the Xinjiang temperate grasslands, alpha diversity was positively and linearly correlated with MAP but unimodally correlated with MAT. Meanwhile, beta diversity was unimodally correlated with MAP but linearly correlated with MAT. Relative to desert steppe, meadow steppe and typical steppe had the highest alpha and beta diversity, respectively. Except for ANPP exhibiting a quadratic relationship with MAP, no significant relationship was found among ANPP, the CV of ANPP and climatic factors. ANPP and the CV of ANPP also exhibited no apparent patterns in variation among different vegetation types. Our results further showed that mean ANPP was closely associated with alpha diversity. Both linear and unimodal relationships were detected between alpha diversity and mean ANPP, but their particular form was texture-dependent. Meanwhile, the CV of ANPP was positively correlated with beta diversity. Our results indicated that in addition to incorporating alpha diversity and mean ANPP, incorporating beta diversity and the CV of ANPP could expand our understanding of the SR-ANPP relationship. PMID:27100676

  6. Characterization of Forested Landscapes From Remotely Sensed Data Using Fractals and Spatial Autocorrelation

    NASA Technical Reports Server (NTRS)

    Al-Hamdan, Mohammad Z.; Cruise, James F.; Rickman, Douglas L.; Quattrochi, Dale A.

    2007-01-01

    The characterization of forested areas is frequently required in resource management practice. Passive remotely sensed data, which are much more accessible and cost effective than are active data, have rarely, if ever, been used to characterize forest structure directly, but rather they usually focus on the estimation of indirect measurement of biomass or canopy coverage. In this study, some spatial analysis techniques are presented that might be employed with Landsat TM data to analyze forest structure characteristics. A case study is presented wherein fractal dimensions, along with a simple spatial autocorrelation technique (Moran s I), were related to stand density parameters of the Oakmulgee National Forest located in the southeastern United States (Alabama). The results of the case study presented herein have shown that as the percentage of smaller diameter trees becomes greater, and particularly if it exceeds 50%, then the canopy image obtained from Landsat TM data becomes sufficiently homogeneous so that the spatial indices reach their lower limits and thus are no longer determinative. It also appears, at least for the Oakmulgee forest, that the relationships between the spatial indices and forest class percentages within the boundaries can reasonably be considered linear. The linear relationship is much more pronounced in the sawtimber and saplings cases than in samples dominated by medium sized trees (poletimber). In addition, it also appears that, at least for the Oakmulgee forest, the relationships between the spatial indices and forest species groups (Hardwood and Softwood) percentages can reasonably be considered linear. The linear relationship is more pronounced in the forest species groups cases than in the forest classes cases. These results appear to indicate that both fractal dimensions and spatial autocorrelation indices hold promise as means of estimating forest stand characteristics from remotely sensed images. However, additional work is needed to confirm that the boundaries identified for Oakmulgee forest and the linear nature of the relationship between image complexity indices and forest characteristics are generally evident in other forests. In addition, the effects of other parameters such ,as topographic relief and image distortion due to sun angle and cloud cover, for example, need to be examined.

  7. Interaction of a magnet and a point charge: Unrecognized internal electromagnetic momentum

    NASA Astrophysics Data System (ADS)

    Boyer, Timothy H.

    2015-05-01

    Whereas nonrelativistic mechanics always connects the total momentum of a system to the motion of the center of mass, relativistic systems, such as interacting electromagnetic charges, can have internal linear momentum in the absence of motion of the system's center of energy. This internal linear momentum of a system is related to the controversial concept of "hidden momentum." We suggest that the term "hidden momentum" be abandoned. Here, we use the relativistic conservation law for the center of energy to give an unambiguous definition of the "internal momentum of a system," and then we exhibit this internal momentum for the system of a magnet (modeled as a circular ring of moving charges) and a distant static point charge. The calculations provide clear illustrations of this system for three cases: (a) the moving charges of the magnet are assumed to continue in their unperturbed motion; (b) the moving charges of the magnet are free to accelerate but have no mutual interactions; and (c) the moving charges of the magnet are free to accelerate and also interact with each other. When the current-carrying charges of the magnet are allowed to interact, the magnet itself will contain internal electromagnetic linear momentum, something that has not been described clearly in the research and teaching literature.

  8. Influence of in situ progressive N-terminal is still controversial truncation of glycogen branching enzyme in Escherichia coli DH5α on glycogen structure, accumulation, and bacterial viability.

    PubMed

    Wang, Liang; Regina, Ahmed; Butardo, Vito M; Kosar-Hashemi, Behjat; Larroque, Oscar; Kahler, Charlene M; Wise, Michael J

    2015-05-07

    Glycogen average chain length (ACL) has been linked with bacterial durability, but this was on the basis of observations across different species. We therefore wished to investigate the relationship between bacterial durability and glycogen ACL by varying glycogen average chain length in a single species. It has been shown that progressive shortening of the N-terminus of glycogen branching enzyme (GBE) leads to a lengthening of oligosaccharide inter-α-1,6-glycosidic chain lengths, so we sought to harness this to create a set of Escherichia coli DH5α strains with a range of glycogen average chain lengths, and assess these strains for durability related attributes, such as starvation, cold and desiccation stress resistance, and biofilm formation. A series of Escherichia coli DH5α mutants were created with glgB genes that were in situ progressively N-terminus truncated. N-terminal truncation shifted the distribution of glycogen chain lengths from 5-11 DP toward 13-50 DP, but the relationship between glgB length and glycogen ACL was not linear. Surprisingly, removal of the first 270 nucleotides of glgB (glgBΔ270) resulted in comparatively high glycogen accumulation, with the glycogen having short ACL. Complete knockout of glgB led to the formation of amylose-like glycogen containing long, linear α1,4-glucan chains with significantly reduced branching frequency. Physiologically, the set of mutant strains had reduced bacterial starvation resistance, while minimally increasing bacterial desiccation resistance. Finally, although there were no obvious changes in cold stress resistance or biofilm forming ability, one strain (glgBΔ180) had significantly increased biofilm formation in favourable media. Despite glgB being the first gene of an operon, it is clear that in situ mutation is a viable means to create more biologically relevant mutant strains. Secondly, there was the suggestion in the data that impairments of starvation, cold and desiccation resistance were worse for the strain lacking glgB, though the first of these was not statistically significant. The results provide prima facie evidence linking abiotic stress tolerance with shorter glycogen ACL. However, further work needs to be done, perhaps in a less labile species. Further work is also required to tease out the complex relationship between glycogen abundance and glycogen structure.

  9. Integrability and correspondence of classical and quantum non-linear three-mode systems

    NASA Astrophysics Data System (ADS)

    Odzijewicz, A.; Wawreniuk, E.

    2018-04-01

    The relationship between classical and quantum three one-mode systems interacting in a non-linear way is described. We investigate the integrability of these systems by using the reduction procedure. The reduced coherent states for the quantum system are constructed. We find the explicit formulas for the reproducing measure for these states. Examples of some applications of the obtained results in non-linear quantum optics are presented.

  10. Acculturation dimensions and 12-month mood and anxiety disorders across US Latino subgroups in the National Epidemiologic Survey of Alcohol and Related Conditions.

    PubMed

    Fernández, R Lewis; Morcillo, C; Wang, S; Duarte, C S; Aggarwal, N K; Sánchez-Lacay, J A; Blanco, C

    2016-07-01

    Individual-level measures of acculturation (e.g. age of immigration) have a complex relationship with psychiatric disorders. Fine-grained analyses that tap various acculturation dimensions and population subgroups are needed to generate hypotheses regarding the mechanisms of action for the association between acculturation and mental health. Study participants were US Latinos (N = 6359) from Wave 2 of the 2004-2005 National Epidemiologic Survey of Alcohol and Related Conditions (N = 34 653). We used linear χ2 tests and logistic regression models to analyze the association between five acculturation dimensions and presence of 12-month DSM-IV mood/anxiety disorders across Latino subgroups (Mexican, Puerto Rican, Cuban, 'Other Latinos'). Acculturation dimensions associated linearly with past-year presence of mood/anxiety disorders among Mexicans were: (1) younger age of immigration (linear χ2 1 = 11.04, p < 0.001), (2) longer time in the United States (linear χ2 1 = 10.52, p < 0.01), (3) greater English-language orientation (linear χ2 1 = 14.57, p < 0.001), (4) lower Latino composition of social network (linear χ2 1 = 15.03, p < 0.001), and (5) lower Latino ethnic identification (linear χ2 1 = 7.29, p < 0.01). However, the associations were less consistent among Cubans and Other Latinos, and no associations with acculturation were found among Puerto Ricans. The relationship between different acculturation dimensions and 12-month mood/anxiety disorder varies across ethnic subgroups characterized by cultural and historical differences. The association between acculturation measures and disorder may depend on the extent to which they index protective or pathogenic adaptation pathways (e.g. loss of family support) across population subgroups preceding and/or following immigration. Future research should incorporate direct measures of maladaptive pathways and their relationship to various acculturation dimensions.

  11. Acculturation dimensions and 12-month mood and anxiety disorders across US Latino subgroups in the National Epidemiologic Survey of Alcohol and Related Conditions

    PubMed Central

    Wang, S.; Duarte, C. S.; Aggarwal, N. K.; Sánchez-Lacay, J. A.; Blanco, C.

    2016-01-01

    Background Individual-level measures of acculturation (e.g. age of immigration) have a complex relationship with psychiatric disorders. Fine-grained analyses that tap various acculturation dimensions and population subgroups are needed to generate hypotheses regarding the mechanisms of action for the association between acculturation and mental health. Method Study participants were US Latinos (N = 6359) from Wave 2 of the 2004–2005 National Epidemiologic Survey of Alcohol and Related Conditions (N = 34 653). We used linear χ2 tests and logistic regression models to analyze the association between five acculturation dimensions and presence of 12-month DSM-IV mood/anxiety disorders across Latino subgroups (Mexican, Puerto Rican, Cuban, ‘Other Latinos’). Results Acculturation dimensions associated linearly with past-year presence of mood/anxiety disorders among Mexicans were: (1) younger age of immigration (linear χ12=11.04, p < 0.001), (2) longer time in the United States (linear χ12=10.52, p < 0.01), (3) greater English-language orientation (linear χ12=14.57, p < 0.001), (4) lower Latino composition of social network (linear χ12=15.03, p < 0.001), and (5) lower Latino ethnic identification (linear χ12=7.29, p < 0.01). However, the associations were less consistent among Cubans and Other Latinos, and no associations with acculturation were found among Puerto Ricans. Conclusions The relationship between different acculturation dimensions and 12-month mood/anxiety disorder varies across ethnic subgroups characterized by cultural and historical differences. The association between acculturation measures and disorder may depend on the extent to which they index protective or pathogenic adaptation pathways (e.g. loss of family support) across population subgroups preceding and/or following immigration. Future research should incorporate direct measures of maladaptive pathways and their relationship to various acculturation dimensions. PMID:27087570

  12. Relationship between age and elite marathon race time in world single age records from 5 to 93 years

    PubMed Central

    2014-01-01

    Background The aims of the study were (i) to investigate the relationship between elite marathon race times and age in 1-year intervals by using the world single age records in marathon running from 5 to 93 years and (ii) to evaluate the sex difference in elite marathon running performance with advancing age. Methods World single age records in marathon running in 1-year intervals for women and men were analysed regarding changes across age for both men and women using linear and non-linear regression analyses for each age for women and men. Results The relationship between elite marathon race time and age was non-linear (i.e. polynomial regression 4th degree) for women and men. The curve was U-shaped where performance improved from 5 to ~20 years. From 5 years to ~15 years, boys and girls performed very similar. Between ~20 and ~35 years, performance was quite linear, but started to decrease at the age of ~35 years in a curvilinear manner with increasing age in both women and men. The sex difference increased non-linearly (i.e. polynomial regression 7th degree) from 5 to ~20 years, remained unchanged at ~20 min from ~20 to ~50 years and increased thereafter. The sex difference was lowest (7.5%, 10.5 min) at the age of 49 years. Conclusion Elite marathon race times improved from 5 to ~20 years, remained linear between ~20 and ~35 years, and started to increase at the age of ~35 years in a curvilinear manner with increasing age in both women and men. The sex difference in elite marathon race time increased non-linearly and was lowest at the age of ~49 years. PMID:25120915

  13. Estimating PM2.5 Concentrations in Xi'an City Using a Generalized Additive Model with Multi-Source Monitoring Data

    PubMed Central

    Song, Yong-Ze; Yang, Hong-Lei; Peng, Jun-Huan; Song, Yi-Rong; Sun, Qian; Li, Yuan

    2015-01-01

    Particulate matter with an aerodynamic diameter <2.5 μm (PM2.5) represents a severe environmental problem and is of negative impact on human health. Xi'an City, with a population of 6.5 million, is among the highest concentrations of PM2.5 in China. In 2013, in total, there were 191 days in Xi’an City on which PM2.5 concentrations were greater than 100 μg/m3. Recently, a few studies have explored the potential causes of high PM2.5 concentration using remote sensing data such as the MODIS aerosol optical thickness (AOT) product. Linear regression is a commonly used method to find statistical relationships among PM2.5 concentrations and other pollutants, including CO, NO2, SO2, and O3, which can be indicative of emission sources. The relationships of these variables, however, are usually complicated and non-linear. Therefore, a generalized additive model (GAM) is used to estimate the statistical relationships between potential variables and PM2.5 concentrations. This model contains linear functions of SO2 and CO, univariate smoothing non-linear functions of NO2, O3, AOT and temperature, and bivariate smoothing non-linear functions of location and wind variables. The model can explain 69.50% of PM2.5 concentrations, with R2 = 0.691, which improves the result of a stepwise linear regression (R2 = 0.582) by 18.73%. The two most significant variables, CO concentration and AOT, represent 20.65% and 19.54% of the deviance, respectively, while the three other gas-phase concentrations, SO2, NO2, and O3 account for 10.88% of the total deviance. These results show that in Xi'an City, the traffic and other industrial emissions are the primary source of PM2.5. Temperature, location, and wind variables also non-linearly related with PM2.5. PMID:26540446

  14. Correlation analysis of the heat capacity and thermal expansion of solid mercury

    NASA Astrophysics Data System (ADS)

    Bodryakov, V. Yu.; Babintsev, Yu. N.

    2015-06-01

    A detailed analysis of the correlation between the volumetric thermal expansion coefficient o( T) and heat capacity C( T) of solid mercury has been performed. It has been shown that there is a clear correlation dependence o( C) not only in the low-temperature range, where it is linear and known as the Grüneisen law, but also up to the melting point of mercury. The dependence o( C) substantially deviates from the low-temperature linear behavior when the heat capacity reaches the classical Dulong-Petit limit of 3 R.

  15. To Design or Not to Design (Part Four): Taking Lines out of Non-Linear; How Design Must Escape ’Tacticization’ Bias of Military Culture

    DTIC Science & Technology

    2011-04-05

    snatch the mouse up, and returns to a nest to feed. What would happen to the well-defined line of operation if a swarm of bees replaced the falcon, and...the mouse with thousands of pollen sources in the diverse topography around a hive? The clear and linear process quickly descends into perceived...Like bees , ants work in colonies where a vast number of very simple creatures function through decentralization and only an awareness of their

  16. The association between ambient temperature and childhood asthma: a systematic review

    NASA Astrophysics Data System (ADS)

    Xu, Zhiwei; Crooks, James Lewis; Davies, Janet Mary; Khan, Al Fazal; Hu, Wenbiao; Tong, Shilu

    2018-03-01

    The objectives of this study are to review available information on the association between ambient temperature and childhood asthma, and to elucidate the possible underlying mechanisms of this relationship. A systematic review was conducted based on the papers retrieved from four databases, including PubMed, ProQuest, ScienceDirect, and Scopus. Papers examining the association of absolute temperature or temperature variation with childhood asthma published from 1 January 2000 to 31 December 2016 were included. Thirteen papers have quantified the effect of absolute temperature on childhood asthma, and six papers have examined the effect of intra- or inter-day temperature variation on childhood asthma. All studies were conducted in urban areas. Aeroallergen sensitizations were only considered in the analyses of one study. Discrepancy existed in the significance of the relationship between absolute temperature and childhood asthma, and also in the shape of this relationship (i.e. linear or non-linear) and whether temperature effects were lagged. Increasing evidence is suggesting non-linear relationship between absolute temperature and childhood asthma. Future research should investigate the burden of childhood asthma specifically attributable to extreme temperatures and temperature variation using advanced statistical approach, particularly in rural areas, after properly considering aeroallergens and air pollution. Projecting future burden of childhood asthma under climate change scenarios is also warranted.

  17. The association between ambient temperature and childhood asthma: a systematic review.

    PubMed

    Xu, Zhiwei; Crooks, James Lewis; Davies, Janet Mary; Khan, Al Fazal; Hu, Wenbiao; Tong, Shilu

    2018-03-01

    The objectives of this study are to review available information on the association between ambient temperature and childhood asthma, and to elucidate the possible underlying mechanisms of this relationship. A systematic review was conducted based on the papers retrieved from four databases, including PubMed, ProQuest, ScienceDirect, and Scopus. Papers examining the association of absolute temperature or temperature variation with childhood asthma published from 1 January 2000 to 31 December 2016 were included. Thirteen papers have quantified the effect of absolute temperature on childhood asthma, and six papers have examined the effect of intra- or inter-day temperature variation on childhood asthma. All studies were conducted in urban areas. Aeroallergen sensitizations were only considered in the analyses of one study. Discrepancy existed in the significance of the relationship between absolute temperature and childhood asthma, and also in the shape of this relationship (i.e. linear or non-linear) and whether temperature effects were lagged. Increasing evidence is suggesting non-linear relationship between absolute temperature and childhood asthma. Future research should investigate the burden of childhood asthma specifically attributable to extreme temperatures and temperature variation using advanced statistical approach, particularly in rural areas, after properly considering aeroallergens and air pollution. Projecting future burden of childhood asthma under climate change scenarios is also warranted.

  18. Nonlinear association of BMI with all-cause and cardiovascular mortality in type 2 diabetes mellitus: a systematic review and meta-analysis of 414,587 participants in prospective studies.

    PubMed

    Zaccardi, Francesco; Dhalwani, Nafeesa N; Papamargaritis, Dimitris; Webb, David R; Murphy, Gavin J; Davies, Melanie J; Khunti, Kamlesh

    2017-02-01

    The relationship between BMI and mortality has been extensively investigated in the general population; however, it is less clear in people with type 2 diabetes. We aimed to assess the association of BMI with all-cause and cardiovascular mortality in individuals with type 2 diabetes mellitus. We searched electronic databases up to 1 March 2016 for prospective studies reporting associations for three or more BMI groups with all-cause and cardiovascular mortality in individuals with type 2 diabetes mellitus. Study-specific associations between BMI and the most-adjusted RR were estimated using restricted cubic splines and a generalised least squares method before pooling study estimates with a multivariate random-effects meta-analysis. We included 21 studies including 24 cohorts, 414,587 participants, 61,889 all-cause and 4470 cardiovascular incident deaths; follow-up ranged from 2.7 to 15.9 years. There was a strong nonlinear relationship between BMI and all-cause mortality in both men and women, with the lowest estimated risk from 31-35 kg/m 2 and 28-31 kg/m 2 (p value for nonlinearity <0.001) respectively. The risk of mortality at higher BMI values increased significantly only in women, whilst lower values were associated with higher mortality in both sexes. Limited data for cardiovascular mortality were available, with a possible inverse linear association with BMI (higher risk for BMI <27 kg/m 2 ). In type 2 diabetes, BMI is nonlinearly associated with all-cause mortality with lowest risk in the overweight group in both men and women. Further research is needed to clarify the relationship with cardiovascular mortality and assess causality and sex differences.

  19. How Important Are Health Care Expenditures for Life Expectancy? A Comparative, European Analysis.

    PubMed

    van den Heuvel, Wim J A; Olaroiu, Marinela

    2017-03-01

    The relationship between health care expenditures and health care outcomes, such as life expectancy and mortality, is complex. Research outcomes show different and contradictory results on this relationship. How and why health care expenditures affect health outcomes is not clear. A causal link between the two is not proven. Without such knowledge, effects of increase/decrease in health care expenses on health outcomes may be overestimated/underestimated. This study analyzes the relationship between life expectancy at birth and expenditures on health care, taking into account expenditures of social production and education, as well as the quantity and quality of health care provisions and lifestyles. This is a cross-sectional study, analyzing national data of 31 European countries. First, the bivariate correlation between the dependent variable and independent variables are calculated and described. Next a forward linear regression analysis is applied. The data are derived from standardized, comparative data bases as available in the Organisation for Economic Co-operation and Development and Eurostat. Health care expenditures are assessed as a percentage of the Gross Domestic Product (GDP). Health care expenditures are not the main determinant of life expectancy at birth, but social protection expenditures are. The regression analysis shows that in countries that spend a high percentage of their GDP on social protection, that have fewer curative beds and low infant mortality, whose citizens report fewer unmet health care needs and drink less alcohol, citizens have a significant longer life expectancy. To realize high life expectancy of citizens, policy measures have to be directed on investment in social protection expenditures, on improving quality of care, and on promoting a healthy life style. Copyright © 2016 AMDA – The Society for Post-Acute and Long-Term Care Medicine. Published by Elsevier Inc. All rights reserved.

  20. Viewing Olfactory Affective Responses Through the Sniff Prism: Effect of Perceptual Dimensions and Age on Olfactomotor Responses to Odors

    PubMed Central

    Ferdenzi, Camille; Fournel, Arnaud; Thévenet, Marc; Coppin, Géraldine; Bensafi, Moustafa

    2015-01-01

    Sniffing, which is the active sampling of olfactory information through the nasal cavity, is part of the olfactory percept. It is influenced by stimulus properties, affects how an odor is perceived, and is sufficient (without an odor being present) to activate the olfactory cortex. However, many aspects of the affective correlates of sniffing behavior remain unclear, in particular the modulation of volume and duration as a function of odor hedonics. The present study used a wide range of odorants with contrasted hedonic valence to test: (1) which psychophysical function best describes the relationship between sniffing characteristics and odor hedonics (e.g., linear, or polynomial); (2) whether sniffing characteristics are sensitive to more subtle variations in pleasantness than simple pleasant-unpleasant contrast; (3) how sensitive sniffing is to other perceptual dimensions of odors such as odor familiarity or edibility; and (4) whether the sniffing/hedonic valence relationship is valid in other populations than young adults, such as the elderly. Four experiments were conducted, using 16–48 odorants each, and recruiting a total of 102 participants, including a group of elderly people. Results of the four experiments were very consistent in showing that sniffing was sensitive to subtle variations in unpleasantness but not to subtle variations in pleasantness, and that, the more unpleasant the odor, the more limited the spontaneous sampling of olfactory information through the nasal cavity (smaller volume, shorter duration). This also applied, although to a lesser extent, to elderly participants. Relationships between sniffing and other perceptual dimensions (familiarity, edibility) were less clear. It was concluded that sniffing behavior might be involved in adaptive responses protecting the subject from possibly harmful substances. PMID:26635683

Top