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Sample records for closed field unbalanced

  1. Study of magnetic thin films deposited by closed-field unbalanced magnetron sputtering

    NASA Astrophysics Data System (ADS)

    Ormston, M. W.; Petford-Long, A. K.; Teer, D. G.

    1999-04-01

    Closed-field unbalanced magnetron sputtering, developed by TEER Coatings Ltd., uses a novel plasma confinement system, which allows controllable high-rate deposition from a wide range of target materials. We report the first use of this technique using ferromagnetic target materials to grow films of nanometer thickness. A study was carried out on a series of Py/Cu/Py and Py/Au/Py magnetic multilayer films, with and without underlayers of Ti or Ta. High-resolution electron microscopy showed that 5 nm of Ti or 15 nm of Ta did not change the structure of the trilayers. The use of Au as a spacer layer induced a texture in the upper Py layer, which decreased its saturation field by half. In situ experiments to observe the effects of an applied field on the domain structure of the films were carried out using Lorentz transmission electron microscopy. Variations in the switching field of the Py layers and of the coupling strength between the Py layers were observed when the thicknesses of the three layers were varied. Double domain wall structures with different wall intensities were observed in some cases. The roughness of the interfaces were increased by ion bombardment; this increased the saturation field of the Py layers.

  2. Unbalanced field RF electron gun

    DOEpatents

    Hofler, Alicia

    2013-11-12

    A design for an RF electron gun having a gun cavity utilizing an unbalanced electric field arrangement. Essentially, the electric field in the first (partial) cell has higher field strength than the electric field in the second (full) cell of the electron gun. The accompanying method discloses the use of the unbalanced field arrangement in the operation of an RF electron gun in order to accelerate an electron beam.

  3. Structures and Properties of C-Doped NiCr Thin Film Deposited by Closed-Field Unbalanced Magnetron Sputtering

    NASA Astrophysics Data System (ADS)

    Lai, Lifei; Wang, Jinxia; Wang, Hongtao; Bao, Mingdong

    2017-01-01

    The structures and properties of C-doped NiCr thin film as embedded thin film resistor (ETFR) materials were studied by closed-field, unbalanced magnetron sputtering method. The C-doped NiCr (NiCrC1) thin film had more stable electrical performance, better corrosion resistance, and higher hardness than NiCr thin film. The temperature coefficient of resistance (TCR) of NiCrC1 thin film deposited at room temperature (from 19.73 ppm/K to 173.7 ppm/K) was lower than that of NiCr thin film (from 157.8 ppm/K to 378.9 ppm/K), and the sheet resistor (154.25 Ω/Sq) was higher than that of NiCr thin film (62.84 Ω/Sq). The preferred orientations of C-doped NiCr thin film was Ni (111), while that of NiCr thin film was Ni (011). The carbon-doped NiCr thin film can reduce the defects and stress and change the preferred orientations. The dominant carbon in C-doped NiCr thin film had a graphite-like structure.

  4. Surface free energy of non-stick coatings deposited using closed field unbalanced magnetron sputter ion plating

    NASA Astrophysics Data System (ADS)

    Sun, Chen-Cheng; Lee, Shih-Chin; Dai, Shyue-Bin; Tien, Shein-Long; Chang, Chung-Chih; Fu, Yaw-Shyan

    2007-02-01

    Semiconductor IC packaging molding dies require wear resistance, corrosion resistance and non-sticking (with a low surface free energy). The molding releasing capability and performance are directly associated with the surface free energy between the coating and product material. The serious sticking problem reduces productivity and reliability. Depositing TiN, TiMoS, ZrN, CrC, CrN, NiCr, NiCrN, CrTiAlN and CrNiTiAlN coatings using closed field unbalanced magnetron sputter ion plating, and characterizing their surface free energy are the main object in developing a non-stick coating system for semiconductor IC molding tools. The contact angle of water, diiodomethane and ethylene glycol on the coated surfaces were measured at temperature in 20 °C using a Dataphysics OCA-20 contact angle analyzer. The surface free energy of the coatings and their components (dispersion and polar) were calculated using the Owens-Wendt geometric mean approach. The surface roughness was investigated by atomic force microscopy (AFM). The adhesion force of these coatings was measured using direct tensile pull-off test apparatus. The experimental results showed that NiCrN, CrN and NiCrTiAlN coatings outperformed TiN, ZrN, NiCr, CiTiAlN, CrC and TiMoS coatings in terms of non-sticking, and thus have the potential as working layers for injection molding industrial equipment, especially in semiconductor IC packaging molding applications.

  5. Closed field unbalanced magnetron sputtering ion plating of Ni/Al thin films: influence of the magnetron power.

    PubMed

    Said, R; Ahmed, W; Gracio, J

    2010-04-01

    In this study NiAl thin films have been deposited using closed field unbalanced magnetron sputtering Ion plating (CFUBMSIP). The influence of magnetron power has been investigated using dense and humongous NiAl compound targets onto stainless steel and glass substrates. Potential applications include tribological, electronic media and bond coatings in thermal barrier coatings system. Several techniques has been used to characterise the films including surface stylus profilometry, energy dispersive spectroscopy (EDAX), X-Ray diffraction (XRD) Composition analysis of the samples was carried out using VGTOF SIMS (IX23LS) and Atomic force microscopy (AFM). Scratch tester (CSM) combined with acoustic emission singles during loading in order to compare the coating adhesion. The acoustic emission signals emitted during the indentation process were used to determine the critical load, under which the film begins to crack and/or break off the substrate. The average thickness of the films was approximately 1 um. EDAX results of NiAl thin films coating with various magnetron power exhibited the near equal atomic% Ni:Al. The best result being obtained using 300 W and 400 W DC power for Ni and Al targets respectively. XRD revealed the presence of beta NiAl phase for all the films coatings. AFM analysis of the films deposited on glass substrates exhibited quite a smooth surface with surface roughness values in the nanometre range. CSM results indicate that best adhesion was achieved at 300 W for Ni, and 400 W for Al targets compared to sample other power values. SIMS depth profile showed a uniform distribution of the Ni and Al component from the surface of the film to the interface.

  6. Structural and tribological properties of CrTiAlN coatings on Mg alloy by closed-field unbalanced magnetron sputtering ion plating

    NASA Astrophysics Data System (ADS)

    Shi, Yongjing; Long, Siyuan; Yang, Shicai; Pan, Fusheng

    2008-09-01

    In this paper, a series of multi-layer hard coating system of CrTiAlN has been prepared by closed-field unbalanced magnetron sputtering ion plating (CFUBMSIP) technique in a gas mixture of Ar + N 2. The coatings were deposited onto AZ31 Mg alloy substrates. During deposition step, technological temperature and metallic atom concentration of coatings were controlled by adjusting the currents of different metal magnetron targets. The nitrogen level was varied by using the feedback control of plasma optical emission monitor (OEM). The structural, mechanical and tribological properties of coatings were characterized by means of X-ray photoelectron spectrometry, high-resolution transmission electron microscope, field emission scanning electron microscope (FESEM), micro-hardness tester, and scratch and ball-on-disc tester. The experimental results show that the N atomic concentration increases and the oxide on the top of coatings decreases; furthermore the modulation period and the friction coefficient decrease with the N 2 level increasing. The outstanding mechanical property can be acquired at medium N 2 level, and the CrTiAlN coatings on AZ31 Mg alloy substrates outperform the uncoated M42 high speed steel (HSS) and the uncoated 316 stainless steel (SS).

  7. Multilayered TiAlN films on Ti6Al4V alloy for biomedical applications by closed field unbalanced magnetron sputter ion plating process.

    PubMed

    Yi, Peiyun; Peng, Linfa; Huang, Jiaqiang

    2016-02-01

    Ti6Al4V alloy has been widely used as a suitable material for surgical implants such as artificial hip joints. In this study, a series of multilayered gradient TiAlN coatings were deposited on Ti6Al4V substrate using closed field unbalanced magnetron sputter ion plating (CFUBMSIP) process. Taguchi design of experiment approach was used to reveal the influence of depositing parameters to the film composition and performance of TiAlN coatings. The phase structure and chemical composition of the TiAlN films were characterized by X-ray diffractometry (XRD) and X-ray photoelectron spectroscopy (XPS). Mechanical properties, including hardness, Young's modulus, friction coefficient, wear rate and adhesion strength were systematically evaluated. Potentiodynamic tests were conducted to evaluate the corrosion resistance of the coated samples in Ringer's solution at 37°C to simulate human body environment. Comprehensive performance of TiAlN films was evaluated by assigning different weight according to the application environment. S8, deposited by Ti target current of 8A, Al target current of 6A, bias voltage of -60V and nitrogen content with OEM (optical emission monitor) value of 45%, was found to achieve best performance in orthogonal experiments. Depositing parameters of S8 might be practically applied for commercialization of surgical implants. Copyright © 2015 Elsevier B.V. All rights reserved.

  8. Growth and characterisation of NiAl and N-doped NiAl films deposited by closed field unbalanced magnetron sputtering ion plating using elemental ni and Al targets.

    PubMed

    Said, R; Ahmed, W; Abuain, T; Abuazza, A; Gracio, J

    2010-04-01

    Closed Field Unbalanced Magnetron Sputtering Ion Plating (CFUBMSIP) has been used to deposit undoped and nitrogen doped NiAI thin films onto glass and stainless steel 316 substrates. These films have potential applications in tribological, electronic media and thermal barrier coatings. The surface characteristics, composition, mechanical and structural properties have been investigated using stylus profilometry, X-ray diffraction (XRD), Energy dispersive spectroscopy (EDAX), Atomic force microscopy (AFM) and nanoindentation. The average thickness of the films was approximately 1 microm. The X-ray diffraction spectra revealed the presence of the beta NiAl phase. The EDAX results revealed that all of the undoped and nitrogen doped NiAl thin films exhibited the near equiatomic NiAl composition with the best results being achieved using 300 Watts DC power for Ni and 400 Watts DC power for Al targets respectively. AFM results of both types of films deposited on glass samples exhibited a surface roughness of less than 100 nm. The nanoindenter results for coatings on glass substrates displayed hardness and elastic modulus of 7.7 GPa and 100 GPa respectively. The hardest coatings obtained were obtained at 10% of nitrogen.

  9. The development of a nanostructured, graded multilayer Cr-CrxNy-Cr1-xAlxN coating produced by pulsed closed field unbalanced magnetron sputtering (P-CFUBMS) for use in aluminum pressure die casting dies.

    PubMed

    Lin, Jianliang; Mishra, Brajendra; Myers, Sterling; Ried, Peter; Moore, John J

    2009-06-01

    The main objective of this research is to design an optimized 'coating system' that extends die life by minimizing premature die failure. The concept of the multilayer coating system with desired combinations of different kinds of single-layer coatings was introduced. A pulsed closed field unbalanced magnetron sputtering (P-CFUBMS) deposition system has been used to deposit Cr-CrxNy-Cr1-xAlxN compositionally graded multilayer coating structures. In this study, three power law scenarios have been adopted to vary the aluminum concentration in the graded Cr1-xAlxN layer: (i) p = 1, the aluminum concentration was increased linearly in the Cr1-xAlxN layer. (ii) p = 0.2, the Cr1-xAlxN layer is an aluminum-rich graded layer, and (iii) p = 2, the Cr1-xAlxN layer is a chromium-rich graded layer. It was found that all the graded coatings exhibit lower residual stress and higher adhesion strength than the homogeneous Cr1-xAlxN (x = 0.585) film. However, different power law grading architectures have significant influence on the hardness and wear resistance of the films. When p = 2 and p = 1, the graded films exhibited relatively low hardness values (24 and 26 GPa respectively) and high COF (0.55 to 0.60). When p = 0.2 the graded film exhibited both high hardness (34 GPa) and good wear resistance (COF = 0.45) due to the structural consistency in the graded zone. The paper discusses the correlation between the pulsing parameters and coating architecture with the resulting nanostructure and tribological properties of this Cr-CrxNy-Cr1-xAlxN coating system.

  10. Women's water polo world championships: technical and tactical aspects of winning and losing teams in close and unbalanced games.

    PubMed

    Lupo, Corrado; Condello, Giancarlo; Capranica, Laura; Tessitore, Antonio

    2014-01-01

    This study aimed to compare the technical and tactical aspects between winning and losing teams in close (i.e., 1-3 goals of difference) and unbalanced (i.e., >3 goals of difference) elite women's water polo games. A notational analysis was performed on 45 games to evaluate occurrence of action, mean duration, action outcome, origin and execution of shot, offensive and defensive role, and arrangement of even, counterattack, power play, and transition situations. Independent 2-sided t-tests were applied to show differences (p < 0.05) between teams. Regarding close games, effects emerged for action outcome (counterattack: lost possessions; power play: goals, no goal shots), origin (even: zone 1, zone 4; counterattack: zone 1, zone 5) and execution (even: off-the-water shots; counterattack: shots after > than 2 fakes; power play: drive shots) of shots, offensive even arrangements (6 vs. 6/5 vs. 5; 2 vs. 2/1 vs. 1), and role. Regarding unbalanced games, differences emerged for the occurrence of action (even, counterattack), duration (even; power play), action outcome (even: goals, penalties; counterattack: goals, no goal shots, penalties; power play: goals, no goal shots; transition: lost possessions), origin (even: zone 2, zone 4; counterattack: zone 5) and execution (even: free throws, drive shots; counterattack: drive shots, shots after > 2 fakes; power play: drive shots, shots after 1 fake) of shots; offensive even arrangements (2 vs. 2/1 vs. 1), and role; and defensive even arrangements (pressing, zones 1-2, zone M, zones 2-3-4). Differences between close and unbalanced games underlining that water polo performance should be analyzed in relation to specific margins of victory. Therefore, water polo coaches and physical trainers can plan a sound training session according to the most important aspects of close (opponent's exclusion, center forward play, and power play actions) and unbalanced (defensive skills) games.

  11. Lorentz Detuning of Superconducting Cavities with Unbalanced Field Profiles

    SciTech Connect

    Delayen, Jean

    2003-05-12

    Tests on the prototype SNS medium beta cryomodule showed a strong correlation between the flatness of the field profile and the Lorentz detuning coefficient (both static and dynamic). We present an analytical model for the enhancement of the Lorentz detuning as a function of the flatness of the field profile resulting from a spread of the frequencies of the individual cells of the cavity.

  12. Closed string field theory from polyhedra

    NASA Astrophysics Data System (ADS)

    Saadi, Maha; Zwiebach, Barton

    1989-05-01

    A fully nonpolynomial framework for closed string field theory is studied. All interactions are geometrical, the pattern of string overlaps gives polyhedra with equal perimeter faces and three edges at each vertex. All interactions are cubic in the sense that at most three strings can coincide at a point. The three point vertex used is that of Witten which is seen to be quite natural in the framework of quadratic differentials and to induce a very symmetric decomposition of moduli space.

  13. Closed-field capacitive liquid level sensor

    DOEpatents

    Kronberg, J.W.

    1998-03-03

    A liquid level sensor based on a closed field circuit comprises a ring oscillator using a symmetrical array of plate units that creates a displacement current. The displacement current varies as a function of the proximity of a liquid to the plate units. The ring oscillator circuit produces an output signal with a frequency inversely proportional to the presence of a liquid. A continuous liquid level sensing device and a two point sensing device are both proposed sensing arrangements. A second set of plates may be located inside of the probe housing relative to the sensing plate units. The second set of plates prevent any interference between the sensing plate units. 12 figs.

  14. Closed-field capacitive liquid level sensor

    DOEpatents

    Kronberg, J.W.

    1995-01-01

    A liquid level sensor based on a closed field circuit comprises a ring oscillator using a symmetrical array of plate units that creates a displacement current. The displacement current varies as a function of the proximity of a liquid to the plate units. The ring oscillator circuit produces an output signal with a frequency inversely proportional to the presence of a liquid. A continuous liquid level sensing device and a two point sensing device are both proposed sensing arrangements. A second set of plates may be located inside of the probe housing relative to the sensing plate units. The second set of plates prevent any interference between the sensing plate units.

  15. Closed-field capacitive liquid level sensor

    DOEpatents

    Kronberg, James W.

    1998-01-01

    A liquid level sensor based on a closed field circuit comprises a ring oscillator using a symmetrical array of plate units that creates a displacement current. The displacement current varies as a function of the proximity of a liquid to the plate units. The ring oscillator circuit produces an output signal with a frequency inversely proportional to the presence of a liquid. A continuous liquid level sensing device and a two point sensing device are both proposed sensing arrangements. A second set of plates may be located inside of the probe housing relative to the sensing plate units. The second set of plates prevent any interference between the sensing plate units.

  16. Quantum fields on closed timelike curves

    SciTech Connect

    Pienaar, J. L.; Myers, C. R.; Ralph, T. C.

    2011-12-15

    Recently, there has been much interest in the evolution of quantum particles on closed timelike curves (CTCs). However, such models typically assume pointlike particles with only two degrees of freedom; a very questionable assumption given the relativistic setting of the problem. We show that it is possible to generalize the Deutsch model of CTCs to fields using the equivalent circuit formalism. We give examples for coherent, squeezed, and single-photon states interacting with the CTC via a beamsplitter. The model is then generalized further to account for the smooth transition to normal quantum mechanics as the CTC becomes much smaller than the size of the modes interacting on it. In this limit, we find that the system behaves like a standard quantum-mechanical feedback loop.

  17. Unbalanced quadriphase demodulator

    NASA Technical Reports Server (NTRS)

    Koybayashi, H. S.; Bradfield, S. P., III (Inventor)

    1977-01-01

    A new and improved apparatus and method are described for demodulation of quaternary phase shift keyed (QPSK) data, particularly unbalanced QPSK. Phase adjustment of the output of a phase locked loop local oscillator is performed to reduce sensitivity to amplitude variations internal to the demodulator.

  18. Take a Field Trip Close to Home.

    ERIC Educational Resources Information Center

    Wood, Jacalyn K.

    1986-01-01

    Describes a simple field trip taken by fourth-grade students to a local park. Aided by volunteers, students go through four learning stations dealing with rock studies, tree identification, following directions (mapping), and observation skills. Presite and postsite activities are discussed. (TW)

  19. Closed expressions for the magnetic field of toroidal multipole configurations

    SciTech Connect

    Sheffield, G.V.

    1983-04-01

    Closed analytic expressions for the vector potential and the magnetic field for the lower order toroidal multipoles are presented. These expressions can be applied in the study of tokamak plasma cross section shaping. An example of such an application is included. These expressions also allow the vacuum fields required for plasma equilibrium to be specified in a general form independent of a particular coil configuration.

  20. Quantum field theory in spaces with closed timelike curves

    NASA Astrophysics Data System (ADS)

    Boulware, David G.

    1992-11-01

    Gott spacetime has closed timelike curves, but no locally anomalous stress energy. A complete orthonormal set of eigenfunctions of the wave operator is found in the special case of a spacetime in which the total deficit angle is 2π. A scalar quantum field theory is constructed using these eigenfunctions. The resultant interacting quantum field theory is not unitary because the field operators can create real, on-shell, particles in the noncausal region. These particles propagate for finite proper time accumulating an arbitrary phase before being annihilated at the same spacetime point as that at which they were created. As a result, the effective potential within the noncausal region is complex, and probability is not conserved. The stress tensor of the scalar field is evaluated in the neighborhood of the Cauchy horizon; in the case of a sufficiently small Compton wavelength of the field, the stress tensor is regular and cannot prevent the formation of the Cauchy horizon.

  1. Hamiltonian description of closed configurations of the vacuum magnetic field

    SciTech Connect

    Skovoroda, A. A.

    2015-05-15

    Methods of obtaining and using the Hamiltonians of closed vacuum magnetic configurations of fusion research systems are reviewed. Various approaches to calculate the flux functions determining the Hamiltonian are discussed. It is shown that the Hamiltonian description allows one not only to reproduce all traditional results, but also to study the behavior of magnetic field lines by using the theory of dynamic systems. The potentialities of the Hamiltonian formalism and its close relation to traditional methods are demonstrated using a large number of classical examples adopted from the fundamental works by A.I. Morozov, L.S. Solov’ev, and V.D. Shafranov.

  2. Quasi-closed orbit in a harmonically perturbed magnetic field

    SciTech Connect

    Stupakov, G.V. )

    1992-11-01

    The paper generalizes a notion of the closed orbit for the case when the accelertor lattice is perturbed by a time-dependent harmonic dipole field. The problem is motivated by effects of current ripple in a proton accelerator. Our result allows to estimate the amplitude of the beam excursions as a function of the amplitude and the frequency of the perturbation. It predicts that the deviation of the beam increases as the frequency of the ripple approaches the sideband betatron frequency.

  3. The electric field close to an undulating interface

    NASA Astrophysics Data System (ADS)

    Kallunki, Jouni; Alava, Mikko; Hellén, E. K. O.

    2006-07-01

    The electric potential close to a boundary between two dielectric material layers reflects the geometry of such an interface. The local variations arise from the combination of material parameters and from the nature of the inhomogeneity. Here, the arising electric field is considered for both a sinusoidally varying boundary and for a "rough," Gaussian test case. We discuss the applicability of a one-dimensional model with the varying layer thickness as a parameter and the generic scaling of the results. As an application we consider the effect of paper roughness on toner transfer in electrophotographic printing.

  4. Modeling and Verification of Distributed Generation and Voltage Regulation Equipment for Unbalanced Distribution Power Systems; Annual Subcontract Report, June 2007

    SciTech Connect

    Davis, M. W.; Broadwater, R.; Hambrick, J.

    2007-07-01

    This report summarizes the development of models for distributed generation and distribution circuit voltage regulation equipment for unbalanced power systems and their verification through actual field measurements.

  5. Closed and open magnetic fields in stellar winds

    SciTech Connect

    Mullan, D.J.; Steinolfson, R.S.

    1983-03-15

    We report on a numerical study of the interaction between a thermal wind and a global dipole field in the Sun and in a giant star. In order for closed field lines to persist near the equator (where a helmet-streamer-like configuration appears), the coronal temperature must be less than a critical value T/sub c/, which scales as M/R. This condition is found to be equivalent to the following: for a static helmet streamer to persist, the sonic point above the helmet must not approach closer to the star than 2.2--2.6 stellar radii. Implications for rapid mass loss and X-ray emission from cool giants are pointed out. Our results strengthen the case for identifying empirical dividing lines in the H-R diagram with a magnetic topology transition locus (MTTL). Support for the MTTL concept is also provided by considerations of the breakdown of magnetostatic equilibrium.

  6. Error probability performance of unbalanced QPSK receivers

    NASA Technical Reports Server (NTRS)

    Simon, M. K.

    1978-01-01

    A simple technique for calculating the error probability performance and associated noisy reference loss of practical unbalanced QPSK receivers is presented. The approach is based on expanding the error probability conditioned on the loop phase error in a power series in the loop phase error and then, keeping only the first few terms of this series, averaging this conditional error probability over the probability density function of the loop phase error. Doing so results in an expression for the average error probability which is in the form of a leading term representing the ideal (perfect synchronization references) performance plus a term proportional to the mean-squared crosstalk. Thus, the additional error probability due to noisy synchronization references occurs as an additive term proportional to the mean-squared phase jitter directly associated with the receiver's tracking loop. Similar arguments are advanced to give closed-form results for the noisy reference loss itself.

  7. Three-dimensional kinematic reconnection in the presence of field nulls and closed field lines

    NASA Technical Reports Server (NTRS)

    Lau, Yun-Tung; Finn, John M.

    1990-01-01

    The present investigation of three-dimensional reconnection of magnetic fields with nulls and of fields with closed lines gives attention to the geometry of the former, with a view to their gamma-line and Sigma-surface structures. The geometric structures of configurations with a pair of type A and B nulls permit reconnection across the null-null lines; these are the field lines which join the two nulls. Also noted is the case of magnetostatic reconnection, in which the magnetic field is time-independent and the electrostatic potential is constant along field lines.

  8. Anomalies in non-polynomial closed string field theory

    NASA Astrophysics Data System (ADS)

    Kaku, Michio

    1990-11-01

    The complete classical action for the non-polynomial closed string field theory was written down last year by the author and the Kyoto group. It successfully reproduces all closed string tree diagrams, but fails to reproduce modular invariant loop amplitudes. In this paper we show that the classical action is also riddled with gauge anomalies. Thus, the classical action is not really gauge invariant and fails as a quantum theory. The presence of gauge anomalies and the violation of modular invariance appear to be a disaster for the theory. Actually, this is a blessing in disguise. We show that by adding new non-polynomial terms to the action, we can simultaneously eliminate both the gauge anomalies and the modular-violating loop diagrams. We show this explicitly at the one loop level and also for an infinite class of p-puncture, genus- g amplitudes, making use of a series of non-trivial identities. The theory is thus an acceptable quantum theory. We comment on the origin of this strange link between local gauge anomalies and global modular invariance.

  9. Unbalanced

    NASA Astrophysics Data System (ADS)

    van den Berg, Ed

    2001-04-01

    These two photos (one of a truck tipping back and one of a donkey cart tipping back) have something in common. The pictures could be used to encourage classroom discussion in small groups using this list of questions.

  10. A vector-free ECG interpretation with P, QRS & T waves as unbalanced transitions between stable configurations of the heart electric field during P-R, S-T & T-P segments

    PubMed Central

    2014-01-01

    Since cell membranes are weak sources of electrostatic fields, this ECG interpretation relies on the analogy between cells and electrets. It is here assumed that cell-bound electric fields unite, reach the body surface and the surrounding space and form the thoracic electric field that consists from two concentric structures: the thoracic wall and the heart. If ECG leads measure differences in electric potentials between skin electrodes, they give scalar values that define position of the electric field center along each lead. Repolarised heart muscle acts as a stable positive electric source, while depolarized heart muscle produces much weaker negative electric field. During T-P, P-R and S-T segments electric field is stable, only subtle changes are detectable by skin electrodes. Diastolic electric field forms after ventricular depolarization (T-P segments in the ECG recording). Telediastolic electric field forms after the atria have been depolarized (P-Q segments in the ECG recording). Systolic electric field forms after the ventricular depolarization (S-T segments in the ECG recording). The three ECG waves (P, QRS and T) can then be described as unbalanced transitions of the heart electric field from one stable configuration to the next and in that process the electric field center is temporarily displaced. In the initial phase of QRS, the rapidly diminishing septal electric field makes measured potentials dependent only on positive charges of the corresponding parts of the left and the right heart that lie within the lead axes. If more positive charges are near the "DOWN" electrode than near the "UP" electrode, a Q wave will be seen, otherwise an R wave is expected. Repolarization of the ventricular muscle is dampened by the early septal muscle repolarization that reduces deflection of T waves. Since the "UP" electrode of most leads is near the usually larger left ventricle muscle, T waves are in these leads positive, although of smaller amplitude and longer

  11. Dynamics of the Open Closed Field Line Boundary

    NASA Astrophysics Data System (ADS)

    Spanswick, E.; Roy, E.; Nishimura, T.; Unick, C.; Jackel, B. J.; Donovan, E.

    2015-12-01

    In most cases, large-scale features of the auroral distribution are the projection, along magnetic field lines, of corresponding magnetospheric features. The poleward boundary of the oval is a key example of such a feature. At almost all local times, this is most often interpreted as the ionospheric marker of the latitudinal transition between open lobe and closed central plasma sheet field lines. Earlier work by Blanchard et al. [J. Geophys. Res., 1995 & 1997] used ground-based photometric observations of 630 nm "redline" aurora and in situ particle observations from simultaneous DMSP overflights to demonstrate that the poleward boundary of the redline aurora is a particularly robust signature of the poleward boundary of the plasma sheet. Owing to the orbits of the DMSP spacecraft and the relative newness of the photometer program (CANOPUS) that provided the optical observations, the Blanchard results represent a limited sampling of magnetic local time and a limited number of events. In this paper we revisit the Blanchard et al study, using particle data from the NASA FAST satellite and the DMSP program, together with redline observations obtained by ground-based All-Sky Imagers. Our results indicate that the Blanchard technique for identifying the polar cap boundary holds true for essentially all magnetic local times on the night side, but that the picture is more nuanced than previously appreciated. Here we present these results, and discuss specific examples where the technique does not work (and explore why). Furthermore, this work is motivated by a new extensive network of highly sensitive redline imagers that has been deployed across northern and central Canada which provides high time resolution large-scale snapshots of the instantaneous polar cap boundary. This in turn enables us to explore magnetospheric dynamics at the interface between the lobe and central plasma sheet in fundamentally new and exciting ways.

  12. Convolutionally-Coded Unbalanced QPSK Systems

    NASA Technical Reports Server (NTRS)

    Divsalar, D.; Yuen, J. H.

    1985-01-01

    Report discusses error-rate performance for three convolutionallycoded unbalanced quadriphase-shift-keying (UQPSK) communication systems with noisy carriers that introduce crosstalk. Systems analyzed unbalanced in sense that each transmits two data streams with different bit rates and (in some cases) different powers.

  13. THE INTERSTELLAR MAGNETIC FIELD CLOSE TO THE SUN. II

    SciTech Connect

    Frisch, P. C.; Andersson, B-G; Berdyugin, A.; Piirola, V.; DeMajistre, R.; Funsten, H. O.; Magalhaes, A. M.; Seriacopi, D. B.; McComas, D. J.; Schwadron, N. A.; Slavin, J. D.; Wiktorowicz, S. J.

    2012-12-01

    The magnetic field in the local interstellar medium (ISM) provides a key indicator of the galactic environment of the Sun and influences the shape of the heliosphere. We have studied the interstellar magnetic field (ISMF) in the solar vicinity using polarized starlight for stars within 40 pc of the Sun and 90 Degree-Sign of the heliosphere nose. In Frisch et al. (Paper I), we developed a method for determining the local ISMF direction by finding the best match to a group of interstellar polarization position angles obtained toward nearby stars, based on the assumption that the polarization is parallel to the ISMF. In this paper, we extend the analysis by utilizing weighted fits to the position angles and by including new observations acquired for this study. We find that the local ISMF is pointed toward the galactic coordinates l, b =47 Degree-Sign {+-} 20 Degree-Sign , 25 Degree-Sign {+-} 20 Degree-Sign . This direction is close to the direction of the ISMF that shapes the heliosphere, l, b =33 Degree-Sign {+-} 4 Degree-Sign , 55 Degree-Sign {+-} 4 Degree-Sign , as traced by the center of the 'Ribbon' of energetic neutral atoms discovered by the Interstellar Boundary Explorer (IBEX) mission. Both the magnetic field direction and the kinematics of the local ISM are consistent with a scenario where the local ISM is a fragment of the Loop I superbubble. A nearby ordered component of the local ISMF has been identified in the region l Almost-Equal-To 0 Degree-Sign {yields} 80 Degree-Sign and b Almost-Equal-To 0 Degree-Sign {yields} 30 Degree-Sign , where PlanetPol data show a distance-dependent increase of polarization strength. The ordered component extends to within 8 pc of the Sun and implies a weak curvature in the nearby ISMF of {approx}0.{sup 0}25 pc{sup -1}. This conclusion is conditioned on the small sample of stars available for defining this rotation. Variations from the ordered component suggest a turbulent component of {approx}23 Degree-Sign . The ordered

  14. Multi-cathode unbalanced magnetron sputtering systems

    NASA Technical Reports Server (NTRS)

    Sproul, William D.

    1991-01-01

    Ion bombardment of a growing film during deposition is necessary in many instances to ensure a fully dense coating, particularly for hard coatings. Until the recent advent of unbalanced magnetron (UBM) cathodes, reactive sputtering had not been able to achieve the same degree of ion bombardment as other physical vapor deposition processes. The amount of ion bombardment of the substrate depends on the plasma density at the substrate, and in a UBM system the amount of bombardment will depend on the degree of unbalance of the cathode. In multi-cathode systems, the magnetic fields between the cathodes must be linked to confine the fast electrons that collide with the gas atoms. Any break in this linkage results in electrons being lost and a low plasma density. Modeling of the magnetic fields in a UBM cathode using a finite element analysis program has provided great insight into the interaction between the magnetic fields in multi-cathode systems. Large multi-cathode systems will require very strong magnets or many cathodes in order to maintain the magnetic field strength needed to achieve a high plasma density. Electromagnets offer the possibility of independent control of the plasma density. Such a system would be a large-scale version of an ion beam enhanced deposition (IBED) system, but, for the UBM system where the plasma would completely surround the substrate, the acronym IBED might now stand for Ion Blanket Enhanced Deposition.

  15. The motion of closed hypersurfaces in the central force fields

    NASA Astrophysics Data System (ADS)

    Yan, Weiping

    2016-08-01

    This paper studies the large time existence for the motion of closed hypersurfaces in a radially symmetric potential. Physically, this surface can be considered as an electrically charged membrane with a constant charge per area in a radially symmetric potential. The evolution of such surface has been investigated by Schnürer and Smoczyk [20]. To study its motion, we introduce a quasi-linear degenerate hyperbolic equation which describes the motion of the surfaces extrinsically. Our main results show the large time existence of such Cauchy problem and the stability with respect to small initial data. When the radially symmetric potential function v ≡ 1, the local existence and stability results have been obtained by Notz [18]. The proof is based on a new Nash-Moser iteration scheme.

  16. Quantum Physics, Fields and Closed Timelike Curves: The D-CTC Condition in Quantum Field Theory

    NASA Astrophysics Data System (ADS)

    Tolksdorf, Jürgen; Verch, Rainer

    2017-07-01

    The D-CTC condition has originally been proposed by David Deutsch as a condition on states of a quantum communication network that contains "backward time-steps" in some of its branches. It has been argued that this is an analogue for quantum processes in the presence of closed timelike curves (CTCs). The unusual properties of states of quantum communication networks that fulfill the D-CTC condition have been discussed extensively in recent literature. In this work, the D-CTC condition is investigated in the framework of quantum field theory in the local, operator-algebraic approach due to Haag and Kastler. It is shown that the D-CTC condition cannot be fulfilled in states that are analytic in the energy, or satisfy the Reeh-Schlieder property, for a certain class of processes and initial conditions. On the other hand, if a quantum field theory admits sufficiently many uncorrelated states across acausally related spacetime regions (as implied by the split property), then the D-CTC condition can always be fulfilled approximately to arbitrary precision. As this result pertains to quantum field theory on globally hyperbolic spacetimes where CTCs are absent, one may conclude that interpreting the D-CTC condition as characteristic for quantum processes in the presence of CTCs could be misleading, and should be regarded with caution. Furthermore, a construction of the quantized massless Klein-Gordon field on the Politzer spacetime, often viewed as spacetime analogue for quantum communication networks with backward time-steps, is proposed in this work.

  17. Non-concentric textured closed surface for huge local field enhancement

    NASA Astrophysics Data System (ADS)

    Xu, Bingzheng; Li, Zhuo; Liu, Liangliang; Sun, Hengyi; Chen, Chen; Xu, Jia; Yuan, Tao; Gu, Changqing

    2017-01-01

    It has been demonstrated that textured closed surfaces are good platforms to support spoof localized surface plasmons with great field confinement and enhancement. Here, we propose a non-concentric textured closed structure to significantly increase the level of field confinement and enhancement. By properly texturing the closed surface with gradient-depth grooves, we show that the incoming electromagnetic waves can be highly confined and focused at the deepest groove on the closed surface. Moreover, we find that the field enhancement factor of this structure is quite sensitive to the polarization angle of the incident wave, which can find potential applications in polarization sensors and energy harvesting devices at microwave and terahertz frequencies.

  18. Existence of standard models of conic fibrations over non-algebraically-closed fields

    SciTech Connect

    Avilov, A A

    2014-12-31

    We prove an analogue of Sarkisov's theorem on the existence of a standard model of a conic fibration over an algebraically closed field of characteristic different from two for three-dimensional conic fibrations over an arbitrary field of characteristic zero with an action of a finite group. Bibliography: 16 titles.

  19. Phenotypic Signatures Arising from Unbalanced Bacterial Growth

    PubMed Central

    Tan, Cheemeng; Smith, Robert Phillip; Tsai, Ming-Chi; Schwartz, Russell; You, Lingchong

    2014-01-01

    Fluctuations in the growth rate of a bacterial culture during unbalanced growth are generally considered undesirable in quantitative studies of bacterial physiology. Under well-controlled experimental conditions, however, these fluctuations are not random but instead reflect the interplay between intra-cellular networks underlying bacterial growth and the growth environment. Therefore, these fluctuations could be considered quantitative phenotypes of the bacteria under a specific growth condition. Here, we present a method to identify “phenotypic signatures” by time-frequency analysis of unbalanced growth curves measured with high temporal resolution. The signatures are then applied to differentiate amongst different bacterial strains or the same strain under different growth conditions, and to identify the essential architecture of the gene network underlying the observed growth dynamics. Our method has implications for both basic understanding of bacterial physiology and for the classification of bacterial strains. PMID:25101949

  20. Closed String S-matrix Elements in Open String Field Theory

    NASA Astrophysics Data System (ADS)

    Garousi, Mohammad R.; Maktabdaran, G. R.

    2005-03-01

    We study the S-matrix elements of the gauge invariant operators corresponding to on-shell closed strings, in open string field theory. In particular, we calculate the tree level S-matrix element of two arbitrary closed strings, and the S-matrix element of one closed string and two open strings. By mapping the world-sheet of these amplitudes to the upper half z-plane, and by evaluating explicitly the correlators in the ghost part, we show that these S-matrix elements are exactly identical to the corresponding disk level S-matrix elements in perturbative string theory.

  1. Prediction and identification of the magnetic field close to electric machines

    NASA Astrophysics Data System (ADS)

    Papadopoulos, Peter J.; Ioannides, Maria G.

    1999-04-01

    The magnetic field around an electric machine operating at full load is predicted numerically and identified experimentally. A precise model of a three-phase induction machine is constructed considering the machine geometry, the windings and the stator and rotor materials. The field distribution close to the machine is determined using the discrete element technique, and actual measurements are carried out for identification purposes. An approximate human model is constructed and the magnetic field inside the human body is computed for a distance of 1 and 5 m from the machine. The magnetic field density is determined at specific points, and the induced current densities are computed.

  2. Translocation of closed polymers through a nanopore under an applied external field

    NASA Astrophysics Data System (ADS)

    Jiang, Shao-Chuan; Zhang, Lin-Xi; Xia, A.-Gen; Chen, Hong-Ping; Cheng, Jun

    2010-01-01

    The dynamic behaviours of the translocations of closed circular polymers and closed knotted polymers through a nanopore, under the driving of an applied field, are studied by three-dimensional Langevin dynamics simulations. The power-law scaling of the translocation time τ with the chain length N and the distribution of translocation time are investigated separately. For closed circular polymers, a crossover scaling of translocation time with chain length is found to be τ simeq Nα, with the exponent α varying from α = 0.71 for relatively short chains to α = 1.29 for longer chains under driving force F = 5. The scaling behaviour for longer chains is in good agreement with experimental results, in which the exponent α = 1.27 for the translocation of double-strand DNA. The distribution of translocation time D(τ) is close to a Gaussian function for duration time τ < τp and follows a falling exponential function for duration time τ > τp. For closed knotted polymers, the scaling exponent α is 1.27 for small field force (F = 5) and 1.38 for large field force (F = 10). The distribution of translocation time D(τ) remarkably features two peaks appearing in the case of large driving force. The interesting result of multiple peaks can conduce to the understanding of the influence of the number of strands of polymers in the pore at the same time on translocation dynamic process and scaling property.

  3. Tongues, bottles, and disconnected loops: The opening and closing of the interplanetary magnetic field

    SciTech Connect

    McComas, D.J.

    1994-06-01

    For years the field of Space Physics has had a problem, a really big problem for it occurs on the largest spatial scales in Space physics -- across the entire region under the Sun`s influence, the heliosphere. The problem is that the Sun appears to keep opening new magnetic flux into interplanetary space with no obvious way for this flux to close back off again. This state of affairs, without some previously unknown method for closing the open interplanetary magnetic field (IMF), leads to an ever growing amount of magnetic flux in interplanetary space: the magnetic flux catastrophe. Recently, considerable progress has been made in understanding why this catastrophic state is not the observed state of the heliosphere. This brief article paints the newly emerging picture of the opening and closing of the IMF and how these processes may account for the observed variation in the amount of magnetic flux in interplanetary space over the solar cycle.

  4. 78 FR 24765 - Notice of Intent To Close 16 Field Offices

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-26

    ... following 16 field offices: Camden, NJ; Syracuse, NY; Orlando, FL; Tampa, FL; Springfield, IL; Cincinnati... will result from the reorganization; (3) a study of the impact on the local economy; and (4) an... closed are: Camden, NJ; Syracuse, NY; Orlando, FL; Tampa, FL; Springfield, IL; Cincinnati, OH; Flint, MI...

  5. Minimum loss reconfiguration of unbalanced distribution networks

    SciTech Connect

    Borozan, V.; Rajicic, D.; Ackovski, R.

    1997-01-01

    A heuristic method for determining the configuration with minimum resistive line losses for three-phase unbalanced distribution networks is described. This method is based on previous papers dealing with balanced network. Using a fast and reliable load flow solution technique and also, efficient algorithms for network elements inspection, so that methodology becomes capable to solve the challenging problem while still maintaining a high execution speed. A developed algorithm is applied on a practical distribution network. Performed analysis highlight the influence of load imbalances on a solution of minimum loss reconfiguration problem.

  6. Direct observation of closed-loop ferrohydrodynamic pumping under traveling magnetic fields

    NASA Astrophysics Data System (ADS)

    Mao, Leidong; Elborai, Shihab; He, Xiaowei; Zahn, Markus; Koser, Hur

    2011-09-01

    Ferrofluid-based liquid manipulation schemes typically actuate an immiscible liquid via a ferrofluid plug, using high magnetic flux (˜1 T) densities and strong field gradients created with bulky permanent magnets. They rely on surface tension effects to maintain the cohesion of the ferrofluid plug, necessitating miniature channels and slow (˜1 μl/min) flow speeds. Here, we demonstrate direct ferrohydrodynamic pumping using traveling magnetic fields at controllable speeds in a simple, closed-loop geometry without any mechanically actuated components. The pumping approach is compact, scalable, and practical. Using moderate field amplitudes (˜10 mT), we obtained a maximum volumetric flow rate of 0.69 ml/s using a readily available commercial ferrofluid. Our closed-loop pumping approach could lead to integrated and efficient liquid manipulation and cooling schemes based on ferrofluids.

  7. On open and closed field line regions in Tsyganenko's field model and their possible associations with horse collar auroras

    NASA Technical Reports Server (NTRS)

    Birn, J.; Hones, E. W., Jr.; Craven, J. D.; Frank, L. A.; Elphinstone, R. D.; Stern, D. P.

    1991-01-01

    The boundary between open and closed field lines is investigated in the empirical Tsyganenko (1987) magnetic field model. All field lines extending to distances beyond -70 R(E), the tailward velocity limit of the Tsyganenko model are defined as open, while all other field lines, which cross the equatorial plane earthward of -70 R(E) and are connected with the earth at both ends, are assumed closed. It is found that this boundary at the surface of the earth, identified as the polar cap boundary, can exhibit the arrowhead shape, pointed toward the sun, which is found in horse collar auroras. For increasing activity levels, the polar cap increases in area and becomes rounder, so that the arrowhead shape is less pronounced. The presence of a net B(y) component can also lead to considerable rounding of the open flux region. The arrowhead shape is found to be closely associated with the increase of B(z) from the midnight region to the flanks of the tail, consistent with a similar increase of the plasma sheet thickness.

  8. On open and closed field line regions in Tsyganenko's field model and their possible associations with horse collar auroras

    NASA Technical Reports Server (NTRS)

    Birn, J.; Hones, E. W., Jr.; Craven, J. D.; Frank, L. A.; Elphinstone, R. D.; Stern, D. P.

    1991-01-01

    The boundary between open and closed field lines is investigated in the empirical Tsyganenko (1987) magnetic field model. All field lines extending to distances beyond -70 R(E), the tailward velocity limit of the Tsyganenko model are defined as open, while all other field lines, which cross the equatorial plane earthward of -70 R(E) and are connected with the earth at both ends, are assumed closed. It is found that this boundary at the surface of the earth, identified as the polar cap boundary, can exhibit the arrowhead shape, pointed toward the sun, which is found in horse collar auroras. For increasing activity levels, the polar cap increases in area and becomes rounder, so that the arrowhead shape is less pronounced. The presence of a net B(y) component can also lead to considerable rounding of the open flux region. The arrowhead shape is found to be closely associated with the increase of B(z) from the midnight region to the flanks of the tail, consistent with a similar increase of the plasma sheet thickness.

  9. On open and closed field line regions in Tsyganenko's field model and their possible associations with horse collar auroras

    SciTech Connect

    Birn, J.; Hones, E.W. Jr. ); Craven, J.D.; Frank, L.A. ); Elphinstone, R.D. ); Stern, D.P. )

    1991-03-01

    Using the empirical Tsyganenko (1987) long model as a prime example of a megnetospheric field model, the authors have attempted to identify the boundary between open and closed field lines. They define as closed all field lines that are connested with the Earth at both ends and cross the equatorial plane earthward of x = {minus}70 R{sub E}, the tailward validity limit of the Tsyganenko model. They find that the form of the open/closed boundary at the Earth's surface, identified with the polar cap boundary, can exhibit the arrowhead shape, pointed toward the Sun, observed in horse collar auroras (Hones et al., 1989). The polar cap size in the Tsyganenko model increases with increasing K{sub p} values, and it becomes rounder and less pointed. The superposition of a net B{sub y} field, which is the expected consequence of an IMF B{sub y}, rotates the polar cap pattern and, for larger values, degrades the arrowhead shape, resulting in polar cap configurations consistent with known asymmetries in the aurora. The pointedness of the polar cap shape also diminishes or even completely disappears if the low-latitude magnetopause is assumed open and located considerably inside of the outermost magnetic flux surface in the Tsyganenko model. The arrowhead shape of the polar cap is found to be associated with a strong increase of B{sub z} from midnight toward the tail flanks, which is observed independently, and is possibly related to the NBZ field-aligned current system, observed during quiet times and strongly northward IMF B{sub z}. The larger B{sub z} values near the flanks of the tail cause more magnetic flux to close through these regions than through the midnight equatorial region.

  10. Quantum field theory in spaces with closed time-like curves

    NASA Astrophysics Data System (ADS)

    Boulware, D. G.

    Gott spacetime has closed timelike curves, but no locally anomalous stress-energy. A complete orthonormal set of eigenfunctions of the wave operator is found in the special case of a spacetime in which the total deficit angle is 27(pi). A scalar quantum field theory is constructed using these eigenfunctions. The resultant interacting quantum field theory is not unitary because the field operators can create real, on-shell, particles in the acausal region. These particles propagate for finite proper time accumulating an arbitrary phase before being annihilated at the same spacetime point as that at which they were created. As a result, the effective potential within the acausal region is complex, and probability is not conserved. The stress tensor of the scalar field is evaluated in the neighborhood of the Cauchy horizon; in the case of a sufficiently small Compton wavelength of the field, the stress tensor is regular and cannot prevent the formation of the Cauchy horizon.

  11. Observations of the Ion Signatures of Double Merging and the Formation of Newly Closed Field Lines

    NASA Technical Reports Server (NTRS)

    Chandler, Michael O.; Avanov, Levon A.; Craven, Paul D.

    2007-01-01

    Observations from the Polar spacecraft, taken during a period of northward interplanetary magnetic field (IMF) show magnetosheath ions within the magnetosphere with velocity distributions resulting from multiple merging sites along the same field line. The observations from the TIDE instrument show two separate ion energy-time dispersions that are attributed to two widely separated (-20Re) merging sites. Estimates of the initial merging times show that they occurred nearly simultaneously (within 5 minutes.) Along with these populations, cold, ionospheric ions were observed counterstreaming along the field lines. The presence of such ions is evidence that these field lines are connected to the ionosphere on both ends. These results are consistent with the hypothesis that double merging can produce closed field lines populated by solar wind plasma. While the merging sites cannot be unambiguously located, the observations and analyses favor one site poleward of the northern cusp and a second site at low latitudes.

  12. Dynamic effects of restoring footpoint symmetry on closed magnetic field lines

    NASA Astrophysics Data System (ADS)

    Reistad, J. P.; Østgaard, N.; Tenfjord, P.; Laundal, K. M.; Snekvik, K.; Haaland, S.; Milan, S. E.; Oksavik, K.; Frey, H. U.; Grocott, A.

    2016-05-01

    Here we present an event where simultaneous global imaging of the aurora from both hemispheres reveals a large longitudinal shift of the nightside aurora of about 3 h, being the largest relative shift reported on from conjugate auroral imaging. This is interpreted as evidence of closed field lines having very asymmetric footpoints associated with the persistent positive y component of the interplanetary magnetic field before and during the event. At the same time, the Super Dual Auroral Radar Network observes the ionospheric nightside convection throat region in both hemispheres. The radar data indicate faster convection toward the dayside in the dusk cell in the Southern Hemisphere compared to its conjugate region. We interpret this as a signature of a process acting to restore symmetry of the displaced closed magnetic field lines resulting in flux tubes moving faster along the banana cell than the conjugate orange cell. The event is analyzed with emphasis on Birkeland currents (BC) associated with this restoring process, as recently described by Tenfjord et al. (2015). Using data from the Active Magnetosphere and Planetary Electrodynamics Response Experiment (AMPERE) during the same conditions as the presented event, the large-scale BC pattern associated with the event is presented. It shows the expected influence of the process of restoring symmetry on BCs. We therefore suggest that these observations should be recognized as being a result of the dynamic effects of restoring footpoint symmetry on closed field lines in the nightside.

  13. Spontaneous Formation of Closed-Field Torus Equilibrium via Current Jump Observed in an Electron-Cyclotron-Heated Plasma

    SciTech Connect

    Yoshinaga, T.; Uchida, M.; Tanaka, H.; Maekawa, T.

    2006-03-31

    Spontaneous current jump resulting in the formation of closed field equilibrium has been observed in electron-cyclotron-heated toroidal plasmas under steady external fields composed of a toroidal field and a relatively weak vertical field in the low aspect ratio torus experiment device. This bridges the gap between the open field equilibrium maintained by a pressure-driven current in the external field and the closed field equilibrium at a larger current. Experimental results and theoretical analyses suggest a current jump model that is based on the asymmetric electron confinement along the field line appearing upon simultaneous transitions of field topology and equilibrium.

  14. Power Analysis in Two-Level Unbalanced Designs

    ERIC Educational Resources Information Center

    Konstantopoulos, Spyros

    2010-01-01

    Previous work on statistical power has discussed mainly single-level designs or 2-level balanced designs with random effects. Although balanced experiments are common, in practice balance cannot always be achieved. Work on class size is one example of unbalanced designs. This study provides methods for power analysis in 2-level unbalanced designs…

  15. Power Analysis in Two-Level Unbalanced Designs

    ERIC Educational Resources Information Center

    Konstantopoulos, Spyros

    2010-01-01

    Previous work on statistical power has discussed mainly single-level designs or 2-level balanced designs with random effects. Although balanced experiments are common, in practice balance cannot always be achieved. Work on class size is one example of unbalanced designs. This study provides methods for power analysis in 2-level unbalanced designs…

  16. Field flatness tuning of TM110 mode cavities with closely spaced modes

    SciTech Connect

    Leo Bellantoni et al.

    2003-10-31

    Superconducting cavities for the CKM RF separated kaon beamline at Fermilab have modes that are closely spaced compared to the resonance bandwidths when warm, and this complicates the field flatness (warm) tuning process. Additionally, it is necessary to maintain the azimuthal orientation of the mode during the tuning deformations. the authors present two analytic techniques to warm-tune cavities with overlapping modes, a finite-element analysis of the tuning process, the design of a warm tuner which maintains mode polarization, and the results of tuning a cavity in which initial manufacturing variations caused the desired {pi} and nearby {pi}-1 modes to be indistinguishable before field flatness tuning.

  17. Unbalanced estrogen metabolism in thyroid cancer.

    PubMed

    Zahid, Muhammad; Goldner, Whitney; Beseler, Cheryl L; Rogan, Eleanor G; Cavalieri, Ercole L

    2013-12-01

    Well-differentiated thyroid cancer most frequently occurs in premenopausal women. Greater exposure to estrogens may be a risk factor for thyroid cancer. To investigate the role of estrogens in thyroid cancer, a spot urine sample was obtained from 40 women with thyroid cancer and 40 age-matched controls. Thirty-eight estrogen metabolites, conjugates and DNA adducts were analyzed by using ultraperformance liquid chromatography/tandem mass spectrometry and the ratio of adducts to metabolites and conjugates was calculated for each sample. The ratio of depurinating estrogen-DNA adducts to estrogen metabolites and conjugates significantly differed between cases and controls (p < 0.0001), demonstrating high specificity and sensitivity. These findings indicate that estrogen metabolism is unbalanced in thyroid cancer and suggest that formation of estrogen-DNA adducts might play a role in the initiation of thyroid cancer. Copyright © 2013 UICC.

  18. Unbalanced Estrogen Metabolism in Thyroid Cancer

    PubMed Central

    Zahid, Muhammad; Goldner, Whitney; Beseler, Cheryl L.; Rogan, Eleanor G.; Cavalieri, Ercole L.

    2013-01-01

    Well-differentiated thyroid cancer most frequently occurs in premenopausal women. Greater exposure to estrogens may be a risk factor for thyroid cancer. To investigate the role of estrogens in thyroid cancer, a spot urine sample was obtained from 40 women with thyroid cancer and 40 age-matched controls. Thirty-eight estrogen metabolites, conjugates and DNA adducts were analyzed by using ultraperformance liquid chromatography/tandem mass spectrometry, and the ratio of adducts to metabolites and conjugates was calculated for each sample. The ratio of depurinating estrogen-DNA adducts to estrogen metabolites and conjugates significantly differed between cases and controls (p<0.0001), demonstrating high specificity and sensitivity. These findings indicate that estrogen metabolism is unbalanced in thyroid cancer and suggest that formation of estrogen-DNA adducts might play a role in the initiation of thyroid cancer. PMID:23686454

  19. Performance of convolutionally coded unbalanced QPSK systems

    NASA Technical Reports Server (NTRS)

    Divsalar, D.; Yuen, J. H.

    1980-01-01

    An evaluation is presented of the performance of three representative convolutionally coded unbalanced quadri-phase-shift-keying (UQPSK) systems in the presence of noisy carrier reference and crosstalk. The use of a coded UQPSK system for transmitting two telemetry data streams with different rates and different powers has been proposed for the Venus Orbiting Imaging Radar mission. Analytical expressions for bit error rates in the presence of a noisy carrier phase reference are derived for three representative cases: (1) I and Q channels are coded independently; (2) I channel is coded, Q channel is uncoded; and (3) I and Q channels are coded by a common 1/2 code. For rate 1/2 convolutional codes, QPSK modulation can be used to reduce the bandwidth requirement.

  20. Close intramolecular sulfur-oxygen contacts: modified force field parameters for improved conformation generation.

    PubMed

    Lupyan, Dmitry; Abramov, Yuriy A; Sherman, Woody

    2012-11-01

    The Cambridge Structural Database (CSD) offers an excellent data source to study small molecule conformations and molecular interactions. We have analyzed 130 small molecules from the CSD containing an intramolecular sulfur-oxygen distance less than the sum of their van der Waals (vdW) radii. Close S···O distances are observed in several important medicinal chemistry motifs (e.g. a carbonyl oxygen connected by a carbon or nitrogen linker to a sulfur) and are not treated well with existing parameters in the MMFFs or OPLS_2005 force fields, resulting in suboptimal geometries and energetics. In this work, we develop modified parameters for the OPLS_2005 force field to better treat this specific interaction in order to generate conformations close to those found in the CSD structures. We use a combination of refitting a force field torsional parameter, adding a specific atom pair vdW term, and attenuating the electrostatic interactions to obtain an improvement in the accuracy of geometry minimizations and conformational searches for these molecules. Specifically, in a conformational search 58 % of the cases produced a conformation less than 0.25 Å from the CSD crystal conformation with the modified OPLS force field parameters developed in this work. In contrast, 25 and 37 % produced a conformation less than 0.25 Å with the MMFFs and OPLS_2005 force fields, respectively. As an application of the new parameters, we generated conformations for the tyrosine kinase inhibitor axitinib (trade name Inlyta) that could be correctly repacked into three observed polymorphic structures, which was not possible with conformations generated using MMFFs or OPLS_2005. The improved parameters can be mapped directly onto physical characteristics of the systems that are treated inadequately with the molecular mechanics force fields used in this study and potentially other force fields as well.

  1. Close intramolecular sulfur-oxygen contacts: modified force field parameters for improved conformation generation

    NASA Astrophysics Data System (ADS)

    Lupyan, Dmitry; Abramov, Yuriy A.; Sherman, Woody

    2012-11-01

    The Cambridge Structural Database (CSD) offers an excellent data source to study small molecule conformations and molecular interactions. We have analyzed 130 small molecules from the CSD containing an intramolecular sulfur-oxygen distance less than the sum of their van der Waals (vdW) radii. Close S···O distances are observed in several important medicinal chemistry motifs (e.g. a carbonyl oxygen connected by a carbon or nitrogen linker to a sulfur) and are not treated well with existing parameters in the MMFFs or OPLS_2005 force fields, resulting in suboptimal geometries and energetics. In this work, we develop modified parameters for the OPLS_2005 force field to better treat this specific interaction in order to generate conformations close to those found in the CSD structures. We use a combination of refitting a force field torsional parameter, adding a specific atom pair vdW term, and attenuating the electrostatic interactions to obtain an improvement in the accuracy of geometry minimizations and conformational searches for these molecules. Specifically, in a conformational search 58 % of the cases produced a conformation less than 0.25 Å from the CSD crystal conformation with the modified OPLS force field parameters developed in this work. In contrast, 25 and 37 % produced a conformation less than 0.25 Å with the MMFFs and OPLS_2005 force fields, respectively. As an application of the new parameters, we generated conformations for the tyrosine kinase inhibitor axitinib (trade name Inlyta) that could be correctly repacked into three observed polymorphic structures, which was not possible with conformations generated using MMFFs or OPLS_2005. The improved parameters can be mapped directly onto physical characteristics of the systems that are treated inadequately with the molecular mechanics force fields used in this study and potentially other force fields as well.

  2. Multi-instrument observation of simultaneous polar cap auroras on open and closed magnetic field lines

    NASA Astrophysics Data System (ADS)

    Reidy, J. A.; Fear, R. C.; Whiter, D. K.; Lanchester, B. S.; Kavanagh, A. J.; Paxton, L. J.; Zhang, Y.; Lester, M.

    2017-04-01

    This paper presents observations of polar cap auroral features on 19 January 2008, evaluated using multiple instruments with near-simultaneous observations in both hemispheres. Analysis of the features indicates that there are at least two formation mechanisms/types of polar cap aurora occurring simultaneously on different magnetic field topologies (one on open and the other on closed magnetospheric field lines). Two high-latitude structures were observed on opposing sides of the northern hemisphere polar cap in the same time interval. The structure on the duskside was formed on closed field lines that protruded into the polar cap and was generated by the precipitation of electrons with energies varying between 2 and 11 keV consistent with an identified mechanism for the formation of transpolar arcs. However, the structure did not extend fully across to the dayside of the auroral oval but rather stayed at ˜80° magnetic latitude for a minimum duration of 40 min. Thus, this structure is an example of a "failed" transpolar arc. The structure on the dawnside of the polar cap was associated with low-energy electron precipitation (less than 1 keV) and no associated ion signatures, which is consistent with it being a common low-intensity arc formed by accelerated polar rain on open field lines. The two separate types of polar cap auroras formed during the same interval, demonstrating the complexity of the solar wind-magnetosphere coupling during the interval.

  3. A New Bench Concept for Measuring Magnetic Fields of Big Closed Structure

    NASA Astrophysics Data System (ADS)

    Campmany, Josep; Ribó, Llibert; Colldelram, Carles; Becheri, Fulvio; Marcos, Jordi; Massana, Valentí

    The measurement of big closed magnetic structures is becoming a challenge of great interest. The main reason is the tendency towards building accelerators with high magnetic fields produced by small gap magnets, as well as the development of cryogenic or superconducting narrow-gap insertion devices. Usual approach, based on side-measurements made with a Hall probe mounted on the tip of a motorized arm based on a long granite bench is no more applicable to such closed structures. So, new concepts and approaches have been developed, mainly based on complex devices that insert a Hall probe inside the magnetic structure maintaining the desired position by close-loop controls. We present in this paper the characterization of a new bench that has been built at ALBA synchrotron that is simple, multi-purpose and can be a general solution for measuring big closed structures. Motion control is done via ICEpap motion driver system using the new trigger feature that has been implemented in this motor controller.

  4. Tracking performance of unbalanced QPSK demodulators. I - Biphase Costas loop with passive arm filters

    NASA Technical Reports Server (NTRS)

    Simon, M. K.; Alem, W. K.

    1978-01-01

    Unbalanced quadriphase-shift-keying (QPSK) is an attractive means for transmitting two digital data streams which in general have different average powers, data rates, and data formats. Previous analyses of the tracking performance of Costas loop demodulators of unbalanced QPSK have accounted only for the filtering effect produced by the loop's two arm filters on the equivalent additive noise perturbing the loop. When the bandwidth of these filters is selected on the basis of the order of the data rate, as is typical of optimum Costas loop design, the filtering degradations of the data modulations themselves and the cross-modulation noise produced by their multiplication in the loop often cannot be neglected. The purpose of this paper is to incorporate these additional filtering effects into the analysis. Many of the results obtained herein are in the form of closed-form expressions which can easily be evaluated numerically for design and performance prediction purposes.

  5. Closed-loop flow test Miravalles Geothermal Field well log results

    SciTech Connect

    Dennis, B.; Eden, G.; Lawton, R.

    1992-10-01

    The Instituto Costarricense de Electricidad (ICE) conducted a closed-loop flow test in the Miravalles Geothermal Field. The closed-loop test was started in May and ran through August of 1990. The effluent from the production well PG-11 was carried by a pipeline through a monitor station to the injection well PG-2. Before starting the long-term flow test in May, cold-water injection experiments were performed in each well to determine the pressure and temperature response. A series of downhole measurements were made in each well to obtain background information. The downhole measurements were repeated in August just before terminating the flow test to evaluate the results.

  6. Closed-loop flow test Miravalles Geothermal Field well log results

    SciTech Connect

    Dennis, B.; Eden, G.; Lawton, R.

    1992-01-01

    The Instituto Costarricense de Electricidad (ICE) conducted a closed-loop flow test in the Miravalles Geothermal Field. The closed-loop test was started in May and ran through August of 1990. The effluent from the production well PG-11 was carried by a pipeline through a monitor station to the injection well PG-2. Before starting the long-term flow test in May, cold-water injection experiments were performed in each well to determine the pressure and temperature response. A series of downhole measurements were made in each well to obtain background information. The downhole measurements were repeated in August just before terminating the flow test to evaluate the results.

  7. Understanding the unbalanced-voltage problem in wind turbine generation

    SciTech Connect

    Muljadi, E.; Butterfield, C.P.; Batan, T.; Yildirim, D.

    2000-02-28

    Most wind turbines are equipped with line-connected induction generators. Induction generators are very attractive as wind turbine generators due to their low cost, ruggedness and the need for little or no maintenance. At constant frequency, the induction generator operates in a small range of speeds and, therefore, it operated with a small range of slips with respect to synchronous speed. Compared to a synchronous generator, an induction generator provides lower stiffness, thus alleviating the mechanical stress. In a weak power system network, an unbalanced load at the distribution lines can cause unbalanced voltage conditions. If an induction generator is connected to an unbalanced voltage, the resulting stator current will be unbalanced. The unbalanced current creates unequal heating (hot spots) on the stator winding. The heat may increase the winding temperature, which degrades the insulation of the winding, i.e., the life expectancy of the winding. Unbalanced currents also create torque pulsation on the shaft resulting in audible noise and extra mechanical stress. This paper explores the unbalanced voltage problem in induction generators. The levels of unbalance and the loads are varied. Experimental and predicted results are presented in this paper.

  8. Acceleration of plasma flows in the closed magnetic fields: Simulation and analysis

    SciTech Connect

    Mahajan, Swadesh M.; Shatashvili, Nana L.; Mikeladze, Solomon V.; Sigua, Ketevan I.

    2006-06-15

    Within the framework of a two-fluid description, possible pathways for the generation of fast flows (dynamical as well as steady) in the closed magnetic fields are established. It is shown that a primary plasma flow (locally sub-Alfvenic) is accelerated while interacting with ambient arcade-like closed field structures. The time scale for creating reasonably fast flows (> or approx. 100 km/s) is dictated by the initial ion skin depth, while the amplification of the flow depends on local plasma {beta}. It is shown that distances over which the flows become 'fast' are {approx}0.01R{sub 0} from the interaction surface (R{sub 0} being a characteristic length of the system); later, the fast flow localizes (with dimensions < or approx. 0.05R{sub 0}) in the upper central region of the original arcade. For fixed initial temperature, the final speed (> or approx. 500 km/s) of the accelerated flow and the modification of the field structure are independent of the time duration (lifetime) of the initial flow. In the presence of dissipation, these flows are likely to play a fundamental role in the heating of the finely structured stellar atmospheres; their relevance to the solar wind is also obvious.

  9. Nonequilibrium problems in Quantum Field Theory and Schwinger's closed time path formalism

    NASA Astrophysics Data System (ADS)

    Cooper, Fred

    1995-04-01

    We review the closed time path formalism of Schwinger using a path integral approach. We apply this formalism to the study of pair production from strong external fields as well as the time evolution of a nonequilibrium chiral phase transition. In 1961 in his classic paper 'Brownian Motion of a Quantum Particle,' Schwinger solved the formidable technical problem of how to use the action principle to study initial value problems. Previously, the action principle was formulated to study only transition matrix elements from an earlier time to a later time. The elegant solution of this problem was the invention of the closed time path (CTP) formalism. This formalism was first used to study field theory problems by Mahanthappa and Bakshi. With the advent of supercomputers, it has now become possible to use this formalism to numerically solve important field theory questions which are presented as initial value problems. Two of these problems we shall review here. They are: (1) The time evolution of the quark-gluon plasma; and (2) Dynamical evolution of a non-equilibrium chiral phase transition following a relativistic heavy ion collision.

  10. Nonequilibrium problems in quantum field theory and Schwinger`s closed time path formalism

    SciTech Connect

    Cooper, F.

    1995-05-01

    We review the closed time path formalism of Schwinger using a path integral approach. We apply this formalism to the study of pair production from strong external fields as well as the time evolution of a nonequilibrium chiral phase transition. In 1961 in his classic paper ``Brownian Motion of a Quantum Particle,`` Schwinger solved the formidable technical problem of how to use the action principle to study initial value problems. Previously, the action principle was formulated to study only transition matrix elements from an earlier time to a later time. The elegant solution of this problem was the invention of the closed time path (CTP) formalism. This formalism was first used to study field theory problems by Mahanthappa and Bakshi. With the advent of supercomputers, it has now become possible to use this formalism to numerically solve important field theory questions which are presented as initial value problems. Two of these problems we shall review here. They are (1) The time evolution of the quark- gluon plasma. (2) Dynamical evolution of a non-equilibrium chiral phase transition following a relativistic heavy ion collision.

  11. Development of a Closed Loop Simulator for Poloidal Field Control in DIII-D

    SciTech Connect

    J.A. Leuer; M.L. Walker; D.A. Humphreys; J.R. Ferron; A. Nerem; B.G. Penaflor

    1999-11-01

    The design of a model-based simulator of the DIII-D poloidal field system is presented. The simulator is automatically configured to match a particular DIII-D discharge circuit. The simulator can be run in a data input mode, in which prior acquired DIII-D shot data is input to the simulator, or in a stand-alone predictive mode, in which the model operates in closed loop with the plasma control system. The simulator is used to design and validate a multi-input-multi-output controller which has been implemented on DIII-D to control plasma shape. Preliminary experimental controller results are presented.

  12. Studies of Dynamic, Radiative Macroscopic Magnetized HED Plasmas with Closed B-Field Lines

    SciTech Connect

    Frese, Michael H.; Frese, Sherry D.

    2013-11-01

    The purpose of this research has been to study the physics of macroscopic magnetized high-energy-density laboratory plasmas (HEDLPs) created through the compression of a high-beta compact toroid (CT) plasma having closed magnetic field lines. The high-beta CT chosen for this work is a field-reversed configuration (FRC). The basic approach is to investigate CT plasmas as they are compressed to a HED state by the electromagnetic implosion of a surrounding metallic shell or solid liner (Figure 1). The shell provides an axisymmetric, electrically-conducting boundary around the plasma and its supporting magnetic field and is imploded by means of the magnetic pressure force arising from axial current flow in the liner interacting with its associated azimuthal magnetic field. Compression of the CT will bring the plasma to fusion temperatures at higher densities and magnetic fields (multi-MegaGauss [MG]) than have previously been present in conventional magnetic fusion approaches. The resulting energy densities will be ~1 Mbar or greater and thus will place the plasma in a parameter space intermediate to MFE and IFE. This work has been a collaboration between the Air Force Research Laboratory, Los Alamos National Laboratory, and NumerEx, LLC.

  13. The retest distribution of the visual field summary index mean deviation is close to normal.

    PubMed

    Anderson, Andrew J; Cheng, Allan C Y; Lau, Samantha; Le-Pham, Anne; Liu, Victor; Rahman, Farahnaz

    2016-09-01

    When modelling optimum strategies for how best to determine visual field progression in glaucoma, it is commonly assumed that the summary index mean deviation (MD) is normally distributed on repeated testing. Here we tested whether this assumption is correct. We obtained 42 reliable 24-2 Humphrey Field Analyzer SITA standard visual fields from one eye of each of five healthy young observers, with the first two fields excluded from analysis. Previous work has shown that although MD variability is higher in glaucoma, the shape of the MD distribution is similar to that found in normal visual fields. A Shapiro-Wilks test determined any deviation from normality. Kurtosis values for the distributions were also calculated. Data from each observer passed the Shapiro-Wilks normality test. Bootstrapped 95% confidence intervals for kurtosis encompassed the value for a normal distribution in four of five observers. When examined with quantile-quantile plots, distributions were close to normal and showed no consistent deviations across observers. The retest distribution of MD is not significantly different from normal in healthy observers, and so is likely also normally distributed - or nearly so - in those with glaucoma. Our results increase our confidence in the results of influential modelling studies where a normal distribution for MD was assumed. © 2016 The Authors Ophthalmic & Physiological Optics © 2016 The College of Optometrists.

  14. Effect of Electromagnetic Brake on Decreasing Unbalanced Flow in Mold

    NASA Astrophysics Data System (ADS)

    Miki, Yuji; Furumai, Kohei

    2015-06-01

    In order to clarify the mechanism of suppression of unbalanced flow in the mold under high throughput conditions in continuous casting, the effect of using an electromagnetic brake on decreasing molten steel momentum and suppressing unbalanced flow in the mold was investigated. (1) The measured value of the effect of the electromagnetic brake on decreasing molten steel momentum was consistent with the calculated value. Molten steel momentum could be reduced by more than 50% when the Stuart number was more than 3. 5. (2) Increased mold level fluctuations caused by unbalanced flow in the mold are suppressed by applying the optimum magnetic flux density with an electromagnetic brake, even under high throughput conditions.

  15. Close-field electroporation gene delivery using the cochlear implant electrode array enhances the bionic ear.

    PubMed

    Pinyon, Jeremy L; Tadros, Sherif F; Froud, Kristina E; Y Wong, Ann C; Tompson, Isabella T; Crawford, Edward N; Ko, Myungseo; Morris, Renée; Klugmann, Matthias; Housley, Gary D

    2014-04-23

    The cochlear implant is the most successful bionic prosthesis and has transformed the lives of people with profound hearing loss. However, the performance of the "bionic ear" is still largely constrained by the neural interface itself. Current spread inherent to broad monopolar stimulation of the spiral ganglion neuron somata obviates the intrinsic tonotopic mapping of the cochlear nerve. We show in the guinea pig that neurotrophin gene therapy integrated into the cochlear implant improves its performance by stimulating spiral ganglion neurite regeneration. We used the cochlear implant electrode array for novel "close-field" electroporation to transduce mesenchymal cells lining the cochlear perilymphatic canals with a naked complementary DNA gene construct driving expression of brain-derived neurotrophic factor (BDNF) and a green fluorescent protein (GFP) reporter. The focusing of electric fields by particular cochlear implant electrode configurations led to surprisingly efficient gene delivery to adjacent mesenchymal cells. The resulting BDNF expression stimulated regeneration of spiral ganglion neurites, which had atrophied 2 weeks after ototoxic treatment, in a bilateral sensorineural deafness model. In this model, delivery of a control GFP-only vector failed to restore neuron structure, with atrophied neurons indistinguishable from unimplanted cochleae. With BDNF therapy, the regenerated spiral ganglion neurites extended close to the cochlear implant electrodes, with localized ectopic branching. This neural remodeling enabled bipolar stimulation via the cochlear implant array, with low stimulus thresholds and expanded dynamic range of the cochlear nerve, determined via electrically evoked auditory brainstem responses. This development may broadly improve neural interfaces and extend molecular medicine applications.

  16. Quasilinear theory of interchange modes in a closed field line configuration

    SciTech Connect

    Kouznetsov, A.; Freidberg, J. P.; Kesner, J.

    2007-10-15

    Two important issues for any magnetic fusion configuration are the maximum achievable values of {beta} and energy confinement time when ideal magnetohydrodynamic (MHD) modes are excited. It is well known that the excitation of the MHD unstable modes typically can lead to violent restructuring of the plasma profiles. The particle and energy transport associated with these modes normally dominates all other transport mechanisms and can lead to plasma disruptions and a rapid loss of energy. This paper analytically investigates the transport of particle density, energy, and magnetic field due to the ideal MHD interchange mode in a closed-line system using the quasilinear approximation. The transport equations are derived for a static plasma in a hardcore Z-pinch configuration and generalized to an arbitrary axisymmetric toroidal closed poloidal field line configuration. It is shown that violation of the marginal stability criterion leads to rapid quasilinear transport that drives the pressure profile back to its marginal profile and forces the particle density to be inversely proportional to {integral}dl/B. The applicability of the quasilinear approximation is numerically tested for the hardcore Z-pinch magnetic configuration using a full nonlinear code.

  17. The close lightning electromagnetic environment: Dart-leader electric field change versus distance

    NASA Astrophysics Data System (ADS)

    Crawford, David E.; Rakov, Vladimir A.; Uman, Martin A.; Schnetzer, George H.; Rambo, Keith J.; Stapleton, Michael V.; Fisher, Richard J.

    2001-07-01

    Net electric field changes due to dart leaders in triggered lightning from experiments conducted in 1997, 1998, and 1999 at the International Center for Lightning Research and Testing at Camp Blanding, Florida, are analyzed and compared with similar data obtained in 1993 at Camp Blanding and at Fort McClellan, Alabama. In 1997-1999 the fields were measured at 2-10 stations with distances from the lightning channel ranging from 10 to 621 m, while in 1993 the fields were measured at three distances, 30, 50, and 110 m, in Florida and at two distances, about 10 and 20 m, in Alabama. With a few exceptions, the 1997-1999 data indicate that the distance dependence of the leader electric field change is close to an inverse proportionality (r-1), in contrast to the 1993 data in which a somewhat weaker distance dependence was observed. The typically observed r-1 dependence is consistent with a uniform distribution of leader charge along the bottom kilometer or so of the channel.

  18. Unbalanced Estrogen Metabolism in Ovarian Cancer

    PubMed Central

    Zahid, Muhammad; Beseler, Cheryl L.; Hall, James B.; LeVan, Tricia; Cavalieri, Ercole L.; Rogan, Eleanor G.

    2013-01-01

    Greater exposure to estrogens is a risk factor for ovarian cancer. To investigate the role of estrogens in ovarian cancer, a spot urine sample and a saliva sample were obtained from 33 women with ovarian cancer and 34 age-matched controls. Thirty-eight estrogen metabolites, conjugates and DNA adducts were analyzed in the urine samples by using ultraperformance liquid chromatography/tandem mass spectrometry, and the ratio of adducts to metabolites and conjugates was calculated for each sample. The ratio of depurinating estrogen-DNA adducts to estrogen metabolites and conjugates was significantly higher in cases compared to controls (p<0.0001), demonstrating high specificity and sensitivity. DNA was purified from the saliva samples and analyzed for genetic polymorphisms in the genes for two estrogen-metabolizing enzymes. Women with two low-activity alleles of catechol-O-methyltransferase plus one or two high-activity alleles of cytochrome P450 1B1 had higher levels of estrogen-DNA adducts and were more likely to have ovarian cancer. These findings indicate that estrogen metabolism is unbalanced in ovarian cancer and suggest that formation of estrogen-DNA adducts plays a critical role in the initiation of ovarian cancer. PMID:24170413

  19. Magnetic fields and leukemia--risk for adults living close to power lines.

    PubMed

    Verkasalo, P K

    1996-01-01

    The objective of this study was to investigate the risk of leukemia from magnetic field exposure among Finnish adults living close to high-voltage power lines. The cohort study included 383700 Finnish people having lived in 1970-1989 within 500 m of overhead power lines of 110-400 kV in a magnetic field calculated to be > or = 0.01 microT. The nested case-cohort study was conducted to investigate dose-response and time-related factors in further detail. Data collection was based on several subsequent record linkages of nationwide registers. The subjects were followed for cancer in 1974-1990, providing over 2.5 million person-years. The outcome measures included standardized incidence ratios, incidence rate ratios, and odds ratios for several exposure indices. The total number of leukemia cases was 203. Magnetic fields were not associated with the overall occurrence of leukemia among adults. The risk estimates were adjusted for age, gender, and municipality; the other covariates had no effect on the risk estimates. However, an almost fivefold increase with statistical significance was observed for the risk of chronic lymphatic leukemia in relation to earlier, or long-lasting, exposure to magnetic fields of > or = 0.1 microT. This finding was based on very small numbers. No risk increases were observed for other types of leukemia. While the possibility of an increase in risk at higher magnetic field levels, or in relation to earlier exposures, cannot be excluded on the basis of this study, the results suggest that typical magnetic fields of high-voltage power lines are not an important cause of leukemia in adults.

  20. TRANSFORMER FOR JOINING UNBALANCED TO BALANCED TRANSMISSION MEANS

    DOEpatents

    Bittner, B.J.; Opperman, R.H.

    1960-06-28

    An improved transformer is invented for joining an unbalanced transmission means to a balanced transmission means and is useful, for example, in transmitting an electromagnetic signal from a coaxial cable to a balanced dipole antenna.

  1. Application of closed-form solutions to a mesh point field in silicon solar cells

    NASA Technical Reports Server (NTRS)

    Lamorte, M. F.

    1985-01-01

    A computer simulation method is discussed that provides for equivalent simulation accuracy, but that exhibits significantly lower CPU running time per bias point compared to other techniques. This new method is applied to a mesh point field as is customary in numerical integration (NI) techniques. The assumption of a linear approximation for the dependent variable, which is typically used in the finite difference and finite element NI methods, is not required. Instead, the set of device transport equations is applied to, and the closed-form solutions obtained for, each mesh point. The mesh point field is generated so that the coefficients in the set of transport equations exhibit small changes between adjacent mesh points. Application of this method to high-efficiency silicon solar cells is described; and the method by which Auger recombination, ambipolar considerations, built-in and induced electric fields, bandgap narrowing, carrier confinement, and carrier diffusivities are treated. Bandgap narrowing has been investigated using Fermi-Dirac statistics, and these results show that bandgap narrowing is more pronounced and that it is temperature-dependent in contrast to the results based on Boltzmann statistics.

  2. Field-based species identification of closely-related plants using real-time nanopore sequencing.

    PubMed

    Parker, Joe; Helmstetter, Andrew J; Devey, Dion; Wilkinson, Tim; Papadopulos, Alexander S T

    2017-08-21

    Advances in DNA sequencing and informatics have revolutionised biology over the past four decades, but technological limitations have left many applications unexplored. Recently, portable, real-time, nanopore sequencing (RTnS) has become available. This offers opportunities to rapidly collect and analyse genomic data anywhere. However, generation of datasets from large, complex genomes has been constrained to laboratories. The portability and long DNA sequences of RTnS offer great potential for field-based species identification, but the feasibility and accuracy of these technologies for this purpose have not been assessed. Here, we show that a field-based RTnS analysis of closely-related plant species (Arabidopsis spp.) has many advantages over laboratory-based high-throughput sequencing (HTS) methods for species level identification and phylogenomics. Samples were collected and sequenced in a single day by RTnS using a portable, "al fresco" laboratory. Our analyses demonstrate that correctly identifying unknown reads from matches to a reference database with RTnS reads enables rapid and confident species identification. Individually annotated RTnS reads can be used to infer the evolutionary relationships of A. thaliana. Furthermore, hybrid genome assembly with RTnS and HTS reads substantially improved upon a genome assembled from HTS reads alone. Field-based RTnS makes real-time, rapid specimen identification and genome wide analyses possible.

  3. The Influence of Magnetic Field Geometry on the Formation of Close-in Exoplanets

    NASA Astrophysics Data System (ADS)

    Simon, Jacob B.

    2016-08-01

    Approximately half of Sun-like stars harbor exoplanets packed within a radius of ˜0.3 au, but the formation of these planets and why they form in only half of known systems are still not well understood. We employ a one-dimensional steady-state model to gain physical insight into the origin of these close-in exoplanets. We use Shakura & Sunyaev α values extracted from recent numerical simulations of protoplanetary disk accretion processes in which the magnitude of α, and thus the steady-state gas surface density, depend on the orientation of large-scale magnetic fields with respect to the disk’s rotation axis. Solving for the metallicity as a function of radius, we find that for fields anti-aligned with the rotation axis, the inner regions of our model disk often fall within a region of parameter space that is not suitable for planetesimal formation, whereas in the aligned case, the inner disk regions are likely to produce planetesimals through some combination of streaming instability and gravitational collapse, though the degree to which this is true depends on the assumed parameters of our model. More robustly, the aligned field case always produces higher concentrations of solids at small radii compared to the anti-aligned case. In the in situ formation model, this bimodal distribution of solid enhancement leads directly to the observed dichotomy in exoplanet orbital distances.

  4. Directly transmitted unbalanced chromosome abnormalities and euchromatic variants

    PubMed Central

    Barber, J

    2005-01-01

    In total, 200 families were reviewed with directly transmitted, cytogenetically visible unbalanced chromosome abnormalities (UBCAs) or euchromatic variants (EVs). Both the 130 UBCA and 70 EV families were divided into three groups depending on the presence or absence of an abnormal phenotype in parents and offspring. No detectable phenotypic effect was evident in 23/130 (18%) UBCA families ascertained mostly through prenatal diagnosis (group 1). In 30/130 (23%) families, the affected proband had the same UBCA as other phenotypically normal family members (group 2). In the remaining 77/130 (59%) families, UBCAs had consistently mild consequences (group 3). In the 70 families with established EVs of 8p23.1, 9p12, 9q12, 15q11.2, and 16p11.2, no phenotypic effect was apparent in 38/70 (54%). The same EV was found in affected probands and phenotypically normal family members in 30/70 families (43%) (group 2), and an EV co-segregated with mild phenotypic anomalies in only 2/70 (3%) families (group 3). Recent evidence indicates that EVs involve copy number variation of common paralogous gene and pseudogene sequences that are polymorphic in the normal population and only become visible at the cytogenetic level when copy number is high. The average size of the deletions and duplications in all three groups of UBCAs was close to 10 Mb, and these UBCAs and EVs form the "Chromosome Anomaly Collection" at http://www.ngrl.org.uk/Wessex/collection. The continuum of severity associated with UBCAs and the variability of the genome at the sub-cytogenetic level make further close collaboration between medical and laboratory staff essential to distinguish clinically silent variation from pathogenic rearrangement. PMID:16061560

  5. Open and closed loop manipulation of charged microchiplets in an electric field

    SciTech Connect

    Lu, J. P. Thompson, J. D.; Whiting, G. L.; Biegelsen, D. K.; Raychaudhuri, S.; Lujan, R.; Veres, J.; Lavery, L. L.; Völkel, A. R.; Chow, E. M.

    2014-08-04

    We demonstrate the ability to orient, position, and transport microchips (“chiplets”) with electric fields. In an open-loop approach, modified four phase traveling wave potential patterns manipulate chiplets in a dielectric solution using dynamic template agitation techniques. Repeatable parallel assembly of chiplets is demonstrated to a positional accuracy of 6.5 μm using electrodes of 200 μm pitch. Chiplets with dipole surface charge patterns are used to show that orientation can be controlled by adding unique charge patterns on the chiplets. Chip path routing is also demonstrated. With a closed-loop control system approach using video feedback, dielectric, and electrophoretic forces are used to achieve positioning accuracy of better than 1 μm with 1 mm pitch driving electrodes. These chip assembly techniques have the potential to enable future printer systems where inputs are electronic chiplets and the output is a functional electronic system.

  6. Wide field adaptive optics laboratory demonstration with closed-loop tomographic control.

    PubMed

    Costille, Anne; Petit, Cyril; Conan, Jean-Marc; Kulcsár, Caroline; Raynaud, Henri-François; Fusco, Thierry

    2010-03-01

    HOMER, the new bench developed at ONERA devoted to wide field adaptive optics (WFAO) laboratory research, has allowed the first experimental validations of multi-conjugate adaptive optics (MCAO) and laser tomography adaptive optics (LTAO) concepts with a linear quadratic Gaussian (LQG) control approach. Results obtained in LTAO in closed loop show the significant gain in performance brought by LQG control, which allows tomographic reconstruction. We present a calibration and model identification strategy. Experimental results are shown to be consistent with end-to-end simulations. These results are very encouraging and demonstrate robustness of performance with respect to inevitable experimental uncertainties. They represent a first step for the study of very large telescope (VLT) and extremely large telescopes (ELT) instruments.

  7. Substrate Heating Effect on c-Axis Texture and Piezoelectric Properties of AlN Thin Films Deposited by Unbalanced Magnetron Sputtering

    NASA Astrophysics Data System (ADS)

    Hasheminiasari, Masood; Lin, Jianliang

    2016-06-01

    Aluminum nitride (AlN) thin films with highly preferred (002) orientations have been reactively deposited by a pulsed-closed field unbalanced magnetron sputtering system using TiN/Ti as the seed/adhesion layer with various substrate temperatures. The texture, orientation and piezoelectric properties of AlN films were characterized by means of x-ray diffraction, rocking curves and laser interferometry. A Michelson laser interferometer was designed and built to obtain the converse piezoelectric response of the deposited AlN thin films. It was found that a slight substrate temperature increase would significantly affect the (002) orientation and the piezoelectric coefficient of AlN thin films compared to the coating obtained with no intentional substrate heating, while higher temperature applications on substrate deteriorated the c-axis texture of the coatings without significant improvement in the piezoelectric response of AlN films.

  8. Methods of Using a Magnetic Field Response Sensor Within Closed, Electrically Conductive Containers

    NASA Technical Reports Server (NTRS)

    Woodward, Stanley E.; Taylor, Bryant D.

    2010-01-01

    Magnetic field response sensors are a class of sensors that are powered via oscillating magnetic fields, and when electrically active, respond with their own magnetic fields with attributes dependent upon the magnitude of the physical quantity being measured. A magnetic field response recorder powers and interrogates the magnetic sensors [see Magnetic-Field-Response Measurement- Acquisition System, NASA Tech Briefs Vol. 30, No, 6 (June 2006, page 28)]. Electrically conductive containers have low transmissivity for radio frequency (RF) energy and thus present problems for magnetic field response sensors. It is necessary in some applications to have a magnetic field response sensor s capacitor placed in these containers. Proximity to conductive surfaces alters the inductance and capacitance of the sensors. As the sensor gets closer to a conductive surface, the electric field and magnetic field energy of the sensor is reduced due to eddy currents being induced in the conductive surface. Therefore, the capacitors and inductors cannot be affixed to a conductive surface or embedded in a conductive material. It is necessary to have a fixed separation away from the conductive material. The minimum distance for separation is determined by the desired sensor response signal to noise ratio. Although the inductance is less than what it would be if it were not in proximity to the conductive surface, the inductance is fixed. As long as the inductance is fixed, all variations of the magnetic field response are due to capacitance changes. Numerous variations of inductor mounting can be utilized, such as providing a housing that provides separation from the conductive material as well as protection from impact damage. The sensor can be on the same flexible substrate with a narrow throat portion of the sensor between the inductor and the capacitor, Figure 1. The throat is of sufficient length to allow the capacitor to be appropriately placed within the container and the inductor

  9. Closing the wildland fire heat budget - measurements in the field at intermediate and operational scales

    NASA Astrophysics Data System (ADS)

    Dickinson, M.; Kremens, R.; Bova, A. S.

    2012-12-01

    Closing the wildland fire heat budget involves characterizing the heat source and energy dissipation across the range of variability in fuels and fire behavior. Meeting this challenge will lay the foundation for predicting direct ecological effects of fires and fire-atmosphere coupling. Here, we focus on the relationships between the fire radiation field, as measured from the zenith, fuel consumption, and the behavior of spreading flame fronts. Experiments were conducted in 8 m x 8 m outdoor plots using pre-conditioned wildland fuels characteristic of mixed-oak forests of the eastern United States. Using dual-band radiometers with a field of view of about 18.5 m^2 at a height of 4.2 m, we found a near-linear increase in fire radiative energy density (FRED) over a range of fuel consumption between 0.15 kg m^-2 to 3.25 kg m^-2. Using an integrated heat budget, we estimate that the fraction of total theoretical combustion energy density radiated from the plot averaged 0.17, the fraction of latent energy transported in the plume averaged 0.08, and the fraction accounted for by the combination of fire convective energy transport and soil heating averaged 0.72. Future work will require, at minimum, instantaneous and time-integrated estimates of energy transported by radiation, convection, and soil heating across a range of fuels. We introduce the Rx-CADRE project through which such measurements are being made.

  10. Mechanical properties of the frog ear: vibration measurements under free- and closed-field acoustic conditions.

    PubMed

    Pinder, A C; Palmer, A R

    1983-10-22

    The acoustically induced motion of the eardrum of the frog was measured by an incoherent optical technique. When free-field sound stimulation was used, the eardrum vibration had a band-pass characteristic with maximum amplitude at 1-2.5 kHz. However, when the sound was presented in a closed-field acoustic coupler the response was low-pass (cut-off frequency about 2.5 kHz). We demonstrate that the motion is the result of the mechanical properties of the eardrum and the sound pressure acting upon it. The net pressure is due to a combination of sound incident directly on the front of the drum and of sound conducted to the rear via internal (resonant) pathways. The frog ear therefore acts as a pressure-gradient receiver at low frequency and a pressure receiver at high frequency. A model is proposed and analysed in terms of its electrical analogue. This model accounts for both our own experimental observations and those of previous studies.

  11. Salvaging dipmeters using an oil field {open_quotes}Dinosaur{close_quotes}

    SciTech Connect

    Breimayer, A.R.P.; Puzio, L.B.

    1996-09-01

    Although state-of-the-art methods such as 3-D seismic and formation imaging tools are widely used, the advantages of the old standard dipmeter should not be dismissed. Seismic dip is subject to velocity errors, and formation imagers cannot be run in all borehole conditions. The dipmeter offers a relatively low cost, highly effective alternative for defining geologic features. The 60{double_prime}= 100{prime} scale playback of the raw dipmeter data may be an oil field {open_quotes}dinosaur,{close_quotes} but it is also the key to assessing the reliability of a dipmeter. This playback should be used to determine CORRELATION QUALITY, critical to the accuracy of any dipmeter. Computer computation of the raw dipmeter data does not always yield reliable dip information, particularly when dipmeters are run under adverse hole conditions or in complex geology. This data can be often salvaged by optical correlation of the 60{close_quote} playback - the process of manually correlating raw dipmeter resistivity curves to determine the attitude of bedding planes in the subsurface. Problems such as tool noise, tool pulls, and poor pad contact compromise data quality. These problems can be recognized and compensated for using optical correlation. Finally, at the 60{double_prime} scale many formation textures and structural characteristics visible on the formation imaging logs are also discernible on the standard dipmeter traces. We will offer many Gulf Coast examples and some hands-on demonstrations using the 60{double_prime} data, and show improved tadpole plots which result from optical correlation.

  12. Measured close lightning leader-step electric-field-derivative waveforms.

    SciTech Connect

    Jordan, Doug M.; Hill, Dustin; Biagi, Christopher J.; Howard, Joseph Sean; Uman, Martin A.; Rakov, Vladimir A.

    2010-12-01

    We characterize the measured electric field-derivative (dE/dt) waveforms of lightning stepped-leader steps from three negative lightning flashes at distances of tens to hundreds of meters. Electromagnetic signatures of leader steps at such close distances have rarely been documented in previous literature. Individual leader-step three-dimensional locations are determined by a dE/dt TOA system. The leader-step field derivative is typically a bipolar pulse with a sharp initial half-cycle of the same polarity as that of the return stroke, followed by an opposite polarity overshoot that decays relatively slowly to background level. This overshoot increases in amplitude relative to the initial peak and becomes dominant as range decreases. The initial peak is often preceded by a 'slow front,' similar to the slow front that precedes the fast transition to peak in first return stroke dE/dt and E waveforms. The overall step-field waveform duration is typically less than 1 {micro}s. The mean initial peak of dE/dt, range-normalized to 100 km, is 7.4 V m{sup -1} {micro}s{sup -1} (standard deviation (S.D.), 3.7 V m{sup -1} {micro}s{sup -1}, N = 103), the mean half-peak width is 33.5 ns (S.D., 11.9 ns, N = 69), and the mean 10-to-90% risetime is 43.6 ns (S.D., 24.2 ns, N = 69). From modeling, we determine the properties of the leader step currents which produced two typical measured field derivatives, and we use one of these currents to calculate predicted leader step E and dE/dt as a function of source range and height, the results being in good agreement with our observations. The two modeled current waveforms had maximum rates of current rise-to-peak near 100 kA {micro}s{sup -1}, peak currents in the 5-7 kA range, current half-peak widths of about 300 ns, and charge transfers of {approx}3 mC. As part of the modeling, those currents were propagated upward at 1.5 x 10{sup 8} m s{sup -1}, with their amplitudes decaying exponentially with a decay height constant of 25 m.

  13. Determination of the North-South Heliospheric Magnetic-Field Component from Inner-Corona Closed-Loop Propagation

    NASA Astrophysics Data System (ADS)

    Jackson, B. V.; Yu, H. S.; Hick, P. P.; Buffington, A.; Bisi, M. M.; Tokumaru, M.; Kim, J.; Hong, S.; Lee, B.; Yi, J.; Yun, J.

    2015-12-01

    We find that a portion of the north-south interplanetary magnetic field measured in situ near Earth is present from a direct outward mapping of closed fields from the low solar corona. Using the Current-Sheet Source Surface (CSSS) model (Zhao & Hoeksema, 1995 JGR 100, 19), these lower coronal fields are extrapolated upward from near the solar surface. Global velocities inferred from a combination of observations of interplanetary scintillation (IPS) matched to in-situ velocities and densities measured by spacecraft instrumentation provide an accurate outward timing to 1 AU from a model assuming conservation of mass and mass flux. The north-south field component at 1 AU is compared with the appropriate ACE magnetometer in-situ Normal (RTN) or Bn field coordinate (Jackson et al., 2015, ApJL, 803:L1). From a significant positive correlation between this method of determining the Bn field compared with in-situ measurements over a three-year period during the last solar minimum, we find that a small fraction of the low-coronal Bn component flux (~1%) regularly escapes from closed-field regions. Since the Bn field provides the major portion of the Geocentric Solar Magnetospheric (GSM) Bz field component that couples most closely to the Earth's geomagnetic field, the prospects for its determination using this technique for space weather use are being actively developed by our many colleague groups.

  14. Improvement of Unbalanced Load Flow Program for Large Power Systems

    NASA Astrophysics Data System (ADS)

    Imai, Shinichi; Suzuki, Haruhiko; Iba, Kenji; Fujiwara, Shuhei

    The idea of unbalanced power flow calculation was proposed many years ago. At that time, however, the needs for such techniques was not an argent issue. But modern power system networks are comprised of long untransposed transmission lines. Therefore, for some kind of analysis, it is now almost impossible to treat a system as though it were a symmetrical network. The aims of most previous studies were oriented to solve voltage/current imbalance in local or small system because local imbalance was a serious concern. This is still an important issue, but more recently our needs have become concentrated on practical bulk power systems, since principal EHV lines are entirely untransposed. Following such a background, we have developed a practical unbalanced load flow program. This program was developed for steady state analysis of large scale of practical networks under many possible unbalanced conditions.

  15. Probability variance CHI feature selection method for unbalanced data

    NASA Astrophysics Data System (ADS)

    Zhang, Xiaowen; Chen, Bingfeng

    2017-08-01

    The problem of feature selection on unbalanced text data is a difficult problem to be solved. In view of the above problems, this paper analyzes the distribution of the feature items in the class and the class and the difference of the document under the unbalanced data set. The research is based on the word frequency probability and the document probability measurement feature and the document in the unbalanced data this paper proposes a CHI feature selection method based on probabilistic variance, which improves the traditional chi-square statistical model by introducing the intra-class word frequency probability factor, inter-class document probability concentration factor and intra-class uniformity factor. The experiment proves the effectiveness and feasibility of the method.

  16. A DETERMINATION OF THE NORTH–SOUTH HELIOSPHERIC MAGNETIC FIELD COMPONENT FROM INNER CORONA CLOSED-LOOP PROPAGATION

    SciTech Connect

    Jackson, B. V.; Hick, P. P.; Buffington, A.; Yu, H.-S.; Bisi, M. M.; Tokumaru, M.; Zhao, X. E-mail: pphick@ucsd.edu E-mail: hsyu@ucsd.edu

    2015-04-10

    A component of the magnetic field measured in situ near the Earth in the solar wind is present from north–south fields from the low solar corona. Using the Current-sheet Source Surface model, these fields can be extrapolated upward from near the solar surface to 1 AU. Global velocities inferred from a combination of interplanetary scintillation observations matched to in situ velocities and densities provide the extrapolation to 1 AU assuming mass and mass flux conservation. The north–south field component is compared with the same ACE in situ magnetic field component—the Normal (Radial Tangential Normal) Bn coordinate—for three years throughout the solar minimum of the current solar cycle. We find a significant positive correlation throughout this period between this method of determining the Bn field compared with in situ measurements. Given this result from a study during the latest solar minimum, this indicates that a small fraction of the low-coronal Bn component flux regularly escapes from closed field regions. The prospects for Space Weather, where the knowledge of a Bz field at Earth is important for its geomagnetic field effects, is also now enhanced. This is because the Bn field provides the major portion of the Geocentric Solar Magnetospheric Bz field coordinate that couples most closely to the Earth’s geomagnetic field.

  17. Response of dayside aurora on closed field lines to solar wind driving

    NASA Astrophysics Data System (ADS)

    Wang, B.; Nishimura, T.; Han, D.; Bortnik, J.; Li, W.; Lyons, L. R.; Angelopoulos, V.; Ebihara, Y.

    2016-12-01

    Diffuse aurora and throat aurora are two major forms of aurora that are observed equatorward of the dayside discrete auroral oval on closed field lines. Dayside diffuse aurora is driven by pitch angle scattering of energetic electrons in the dayside magnetosphere by whistler mode waves, and often show transient brightenings. Throat aurora is transient discrete auroral brightening in the dayside region with roughly north-south orientation, extending equatorward of the discrete auroral oval. Throat aurora is associated with enhanced precipitation of low-energy electrons with 100 eV. However, the magnetospheric signatures and the upstream drivers of these localized aurora variations are still open questions. With conjunction observations by multiple Time History of Events and Macroscale Interactions during Substorms (THEMIS) satellites (TH-A, TH-B, TH-C, TH-D, TH-E) and South Pole station all-sky imager (ASI), 4 cases of auroral brightenings (2 diffuse aurora and 2 throat aurora) are identified on Jun. 25th, 2008. In 2 diffuse aurora brightening cases, foreshock ions are found to have a roughly one-to-one relation with brightenings of diffuse auroral intensity. Simultaneously, the localized magnetopause compression signatures and magnetosheath particle penetration are observed around those brightening times, indicating localized magnetosphere compression by foreshock effects and magnetosheath particle penetration to dayside outer magnetosphere for driving diffuse auroral brightening. In the 2 cases with throat aurora, pulses of low-energy ions flowing earthward were found in the dayside magnetosphere, and FTE-like signatures were found in the magnetosheath. These connections suggest that throat aurora reflects transient and localized reconnection, magnetosheath particle penetration, and flow burst.

  18. Topics in Covariant Closed String Field Theory and Two-Dimensional Quantum Gravity

    NASA Astrophysics Data System (ADS)

    Saadi, Maha

    1991-01-01

    The closed string field theory based on the Witten vertex is found to be nonpolynomial in order to reproduce all tree amplitudes correctly. The interactions have a geometrical pattern of overlaps, which can be thought as the edges of a spherical polyhedron with face-perimeters equal to 2pi. At each vertex of the polyhedron there are three faces, thus all elementary interactions are cubic in the sense that at most three strings can coincide at a point. The quantum action is constructed by substracting counterterms which cancel the overcounting of moduli space, and by adding loop vertices in such a way no possible surfaces are missed. A counterterm that gives the correct one-string one-loop amplitude is formulated. The lowest order loop vertices are analyzed in the cases of genus one and two. Also, a one-loop two -string counterterm that restores BRST invariance to the respective scattering amplitude is constructed. An attempt to understand the formulation of two -dimensional pure gravity from the discrete representation of a two-dimensional surface is made. This is considered as a toy model of string theory. A well-defined mathematical model is used. Its continuum limit cannot be naively interpreted as pure gravity because each term of the sum over surfaces is not positive definite. The model, however, could be considered as an analytic continuation of the standard matrix model formulation of gravity. (Copies available exclusively from MIT Libraries, Rm. 14-0551, Cambridge, MA 02139-4307. Ph. 617-253-5668; Fax 617-253-1690.).

  19. Spatial kinematics of Brightest Cluster Galaxies and their close companions from Integral Field Unit spectroscopy

    NASA Astrophysics Data System (ADS)

    Brough, S.; Tran, K.-V.; Sharp, R. G.; von der Linden, A.; Couch, Warrick J.

    2011-06-01

    We present Integral Field Unit (IFU) spectroscopy of four brightest cluster galaxies (BCGs) at z ˜ 0.1. Three of the BCGs have close companions within a projected radius of 20 kpc and one has no companion within that radius. We calculate the dynamical masses of the BCGs and their companions to be ?. We estimate the probability that the companions of the BCGs are bound using the observed masses and velocity offsets. We show that the lowest mass companion (1:4) is not bound while the two nearly equal mass (1:1.45 and 1:1.25) companions are likely to merge with their host BCGs in 0.35 Gyr in major, dry mergers. We conclude that some BCGs continue to grow from major merging even at z ˜ 0. We analyse the stellar kinematics of these systems using the λR parameter developed by the SAURON team. This offers a new and unique means to measure the stellar angular momentum of BCGs and make a direct comparison to other early-type galaxies. The BCGs and their companions have similar ellipticities to those of other early-type galaxies but are more massive. We find that not all these massive galaxies have low ? as one might expect. One of the four BCGs and the two massive companions are found to be fast-rotating galaxies with high angular momentum, thereby providing a new test for models of galaxy evolution and the formation of intracluster light. Based on VLT service mode observations (Programme 381.B-0728) gathered at the European Southern Observatory, Chile.

  20. Computational model for calculating the dynamical behaviour of generators caused by unbalanced magnetic pull and experimental validation

    NASA Astrophysics Data System (ADS)

    Pennacchi, Paolo

    2008-04-01

    The modelling of the unbalanced magnetic pull (UMP) in generators and the experimental validation of the proposed method are presented in this paper. The UMP is one of the most remarkable effects of electromechanical interactions in rotating machinery. As a consequence of the rotor eccentricity, the imbalance of the electromagnetic forces acting between rotor and stator generates a net radial force. This phenomenon can be avoided by means of a careful assembly and manufacture in small and stiff machines, like electrical motors. On the contrary, the eccentricity of the active part of the rotor with respect to the stator is unavoidable in big generators of power plants, because they operate above their first critical speed and are supported by oil-film bearings. In the first part of the paper, a method aimed to calculate the UMP force is described. This model is more general than those available in literature, which are limited to circular orbits. The model is based on the actual position of the rotor inside the stator, therefore on the actual air-gap distribution, regardless of the orbit type. The closed form of the nonlinear UMP force components is presented. In the second part, the experimental validation of the proposed model is presented. The dynamical behaviour in the time domain of a steam turbo-generator of a power plant is considered and it is shown that the model is able to reproduce the dynamical effects due to the excitation of the magnetic field in the generator.

  1. Regional Conference on the Analysis of the Unbalanced Mixed Model.

    DTIC Science & Technology

    1987-12-31

    this complicated problem. Paper titles: The Present Status of Confidence Interval Estimation on Variance Components in Balanced and Unbalanced Random...Models; Prediction-Interval Procedures and (Fixed Effects) Confidence - Interval Procedures for Mixed Linear Models; The Use of Equivalent linear Models

  2. Visualization in Mechanics: The Dynamics of an Unbalanced Roller

    ERIC Educational Resources Information Center

    Cumber, Peter S.

    2017-01-01

    It is well known that mechanical engineering students often find mechanics a difficult area to grasp. This article describes a system of equations describing the motion of a balanced and an unbalanced roller constrained by a pivot arm. A wide range of dynamics can be simulated with the model. The equations of motion are embedded in a graphical…

  3. Visualization in Mechanics: The Dynamics of an Unbalanced Roller

    ERIC Educational Resources Information Center

    Cumber, Peter S.

    2017-01-01

    It is well known that mechanical engineering students often find mechanics a difficult area to grasp. This article describes a system of equations describing the motion of a balanced and an unbalanced roller constrained by a pivot arm. A wide range of dynamics can be simulated with the model. The equations of motion are embedded in a graphical…

  4. On the inversion of polarity of the electric field at very close range from a tower struck by lightning

    NASA Astrophysics Data System (ADS)

    Mosaddeghi, A.; Pavanello, D.; Rachidi, F.; Rubinstein, M.

    2007-10-01

    In this paper, we show that the electric field generated by a lightning return stroke to a tall structure can change polarity at very close distance range, typically at distances of about one tenth the height or so of the struck object. This change in the polarity seems to be a specific signature of the very close vertical electric field. Two different theoretical explanations of such an inversion of polarity are given, the first based on general field equations for a perfectly conducting ground and the second based on the equation derived by Baba and Rakov (2005a) for the case when the return stroke wavefront speed is assumed to be equal to the speed of light and the reflection coefficient at the top of the tall structure is zero. A simple equation is derived which provides an estimate of the critical distance below which such an inversion of polarity might occur. It is also shown that the inversion of polarity depends on the value of the reflection coefficient at the base of the tower and disappears for reflection coefficients close to 1. On the other hand, other parameters such as the return stroke speed, the reflection coefficient at the top of the strike object, and the adopted return stroke model seem not to have an impact on the inversion of polarity. The need of obtaining experimental data on electromagnetic fields at very close range to a tower struck by lightning is emphasized in order to confirm the theoretical finding.

  5. Closely-spaced double-row microstrip RF arrays for parallel MR imaging at ultrahigh fields.

    PubMed

    Yan, Xinqiang; Xue, Rong; Zhang, Xiaoliang

    2015-11-01

    Radiofrequency (RF) coil arrays with high count of elements, e.g., closely-spaced multi-row arrays, exhibit superior parallel imaging performance in MRI. However, it is technically challenging and time-consuming to build multi-row arrays due to complex coupling issues. This paper presents a novel and simple method for closely-spaced multi-row RF array designs. Induced current elimination (ICE) decoupling method has shown the capability of reducing coupling between microstrip elements from different rows. In this study, its capability for decoupling array elements from the same row was investigated and validated by bench tests, with an isolation improvement from -8.9 dB to -20.7 dB. Based on this feature, a closely-spaced double-row microstrip array with 16 elements was built at 7T. S21 between any two elements of the 16-channel closely-spaced was better than -14 dB. In addition, its feasibility and performance was validated by MRI experiments. No significant image reconstruction- related noise amplifications were observed for parallel imaging even when reduced factor (R) achieves 4. The experimental results demonstrated that the proposed design might be a simple and efficient approach in fabricating closely-spaced multi-row RF arrays.

  6. Closely-spaced double-row microstrip RF arrays for parallel MR imaging at ultrahigh fields

    PubMed Central

    Yan, Xinqiang; Xue, Rong; Zhang, Xiaoliang

    2015-01-01

    Radiofrequency (RF) coil arrays with high count of elements, e.g., closely-spaced multi-row arrays, exhibit superior parallel imaging performance in MRI. However, it is technically challenging and time-consuming to build multi-row arrays due to complex coupling issues. This paper presents a novel and simple method for closely-spaced multi-row RF array designs. Induced current elimination (ICE) decoupling method has shown the capability of reducing coupling between microstrip elements from different rows. In this study, its capability for decoupling array elements from the same row was investigated and validated by bench tests, with an isolation improvement from −8.9 dB to −20.7 dB. Based on this feature, a closely-spaced double-row microstrip array with 16 elements was built at 7T. S21 between any two elements of the 16-channel closely-spaced was better than −14 dB. In addition, its feasibility and performance was validated by MRI experiments. No significant image reconstruction- related noise amplifications were observed for parallel imaging even when reduced factor (R) achieves 4. The experimental results demonstrated that the proposed design might be a simple and efficient approach in fabricating closely-spaced multi-row RF arrays. PMID:26508810

  7. Open and closed string vertices for branes with magnetic field and T-duality

    NASA Astrophysics Data System (ADS)

    Pesando, Igor

    2010-02-01

    We discuss carefully the vertices which describe the dipole open strings and closed strings on a D-brane with magnetic flux on a torus. Translation invariance along closed cycles forces surprisingly closed string vertices written in open string formalism to acquire Chan-Paton like matrices. Moreover the one loop amplitudes have a single trace for the part of gauge group with the magnetic flux. These peculiarities are also required by consistency of the action of T-duality in the open string sector. In this way we can show to all orders in perturbation theory the equivalence of the T-dual open string theories, gravitational interactions included. We provide also a new and direct derivation of the bosonic boundary state in presence of constant magnetic and Kalb-Ramond background based on Sciuto-Della Selva-Saito vertex formalism.

  8. Comparison of hydrodynamic and semi-kinetic treatments for plasma flow along closed field lines

    NASA Technical Reports Server (NTRS)

    Singh, Nagendra; Wilson, G. R.; Horwitz, J. L.

    1993-01-01

    Hydrodynamic and semi-kinetic treatments of plasma flow along closed geomagnetic field lines are compared. The hydrodynamic treatment is based on a simplified 16-moment set of transport equations as the equations for the heat flows are not solved; the heat flows are treated heuristically. The semi-kinetic treatment is based on a particle code. The comparison deals with the distributions of the plasma density, flow velocity, and parallel and perpendicular temperatures as obtained from the two treatments during the various stages of the flow. In the kinetic treatment, the appropriate boundary condition is the prescription of the velocity distribution functions for the particles entering the flux tubes at the ionospheric boundaries; those particles leaving the system are determined by the processes occurring in the flux tube. The prescribed distributions are half-Maxwellian with temperature T(sub 0) and density n(sub 0). In the hydrodynamic model, the prescribed boundary conditions are on density (n(sub 0)), flow velocity (V(sub 0)) and temperature (T(sub 0). It was found that results from the hydrodynamic treatment critically depend on V(sub 0); for early stages of the flow this treatment yields results in good agreement with those from the kinetic treatment, when V(sub 0) = square root of (kT(sub 0)/2 (pi)m), which is the average velocity of particles moving in a given direction for a Maxwellian distribution. During this early stage, the flows developing form the conjugate ionospheres show some distinct transitions. For the first hour or so, the flows are highly supersonic and penetrate deep into the opposite hemispheres, and both hydrodynamics and kinetic treatments yield almost similar features. It is found that during this period heatflow effects are negligibly small. When a flow penetrates deep into the opposite hemisphere, the kinetic treatment predicts reflection and setting up of counterstreaming. In contrast, the hydrodynamic treatment yields a shock in the

  9. Electric field statistics for close lightning return strokes near Gainesville, Florida

    NASA Technical Reports Server (NTRS)

    Tiller, J. A.; Uman, M. A.; Lin, Y. T.; Brantley, R. D.; Krider, E. P.

    1976-01-01

    The salient properties of the electric field intensity from first and subsequent lightning return strokes in the 0-25 km distance range near Gainesville, Fla., are presented, including electric field wave shape versus distance, initial peak rise time versus distance, rise time histograms, initial peak magnitude versus distance, normalized (to 100 km) initial peak magnitude histograms, normalized initial peak magnitude versus rise time, ramp starting time versus distance, and field at 170 microsec versus distance. The mean normalized initial peak field for first return strokes was 9.9 V/m and for subsequent strokes, 5.7 V/m. The maximum measured values of normalized initial peak field were about 30 V/m. The largest field recorded at 170 microsec was about 25 kV/m generated by a first stroke within 0.5 km. Return strokes were found to lower a typical charge of the order of 1 C in 170 microsec.

  10. Involved field radiation for Hodgkin's lymphoma: The actual dose to breasts in close proximity

    SciTech Connect

    Dabaja, Bouthaina; Wang Zhonglo; Stovall, Marilyn; Baker, Jamie S.; Smith, Susan A.; Khan, Meena; Ballas, Leslie; Salehpour, Mohammad R.

    2012-01-01

    To decrease the risk of late toxicities in Hodgkin's lymphoma (HL) patients treated with radiation therapy (RT) (HL), involved field radiation therapy (IFRT) has largely replaced the extended fields. To determine the out-of-field dose delivered from a typical IFRT to surrounding critical structures, we measured the dose at various points in an anthropomorphic phantom. The phantom is divided into 1-inch-thick slices with the ability to insert TLDs at 3-cm intervals grid spacing. Two treatment fields were designed, and a total of 45 TLDs were placed (equally spaced) at the margin of the each of the 2 radiation fields. After performing a computed tomography simulation, 2 treatment plans targeting the mediastinum, a typical treatment field in patients with early stage HL, were generated. A total dose of 3060 cGy was delivered to the gross tumor volume for each field consecutively. The highest measured dose detected at 1 cm from the field edge in the planning target volume was 496 cGy, equivalent to 16% of the isocentric dose. The dose dropped significantly with increasing distance from the field edge. It ranged from 1.1-3.9% of the isocentric dose at a distance of 3.2-4 cm to <1.6% at a distance of >6 cm. Although the computer treatment planning system (CTPS) frequently underestimated the dose delivered, the difference in dose between measured and generated by CTPS was <2.5% in 90 positions measured. The collateral dose of radiation to breasts from IFRT is minimal. The out-of-field dose, although mildly underestimated by CTPS, becomes insignificant at >3 cm from the field edge of the radiation field.

  11. Processing of Signals from Fiber Bragg Gratings Using Unbalanced Interferometers

    NASA Technical Reports Server (NTRS)

    Adamovsky, Grigory; Juergens, Jeff; Floyd, Bertram

    2005-01-01

    Fiber Bragg gratings (FBG) have become preferred sensory structures in fiber optic sensing system. High sensitivity, embedability, and multiplexing capabilities make FBGs superior to other sensor configurations. The main feature of FBGs is that they respond in the wavelength domain with the wavelength of the returned signal as the indicator of the measured parameter. The wavelength is then converted to optical intensity by a photodetector to detect corresponding changes in intensity. This wavelength-to-intensity conversion is a crucial part in any FBG-based sensing system. Among the various types of wavelength-to-intensity converters, unbalanced interferometers are especially attractive because of their small weight and volume, lack of moving parts, easy integration, and good stability. In this paper we investigate the applicability of unbalanced interferometers to analyze signals reflected from Bragg gratings. Analytical and experimental data are presented.

  12. Design and simulation of a sensor for heliostat field closed loop control

    NASA Astrophysics Data System (ADS)

    Collins, Mike; Potter, Daniel; Burton, Alex

    2017-06-01

    Significant research has been completed in pursuit of capital cost reductions for heliostats [1],[2]. The camera array closed loop control concept has potential to radically alter the way heliostats are controlled and installed by replacing high quality open loop targeting systems with low quality targeting devices that rely on measurement of image position to remove tracking errors during operation. Although the system could be used for any heliostat size, the system significantly benefits small heliostats by reducing actuation costs, enabling large numbers of heliostats to be calibrated simultaneously, and enabling calibration of heliostats that produce low irradiance (similar or less than ambient light images) on Lambertian calibration targets, such as small heliostats that are far from the tower. A simulation method for the camera array has been designed and verified experimentally. The simulation tool demonstrates that closed loop calibration or control is possible using this device.

  13. Unbalanced rock mass vibration generator and its bench testing

    NASA Astrophysics Data System (ADS)

    Rybalkin, LA; Azarov, AV; Serdyukov, AS

    2017-02-01

    This work presents an unbalanced borehole vibration source with the pneumatic actuator to affect the rock mass bottomhole zone in the seismic frequency range. The modulus-type source consists of the vibration generator with automatic step regulation of static moment, clamping node and built-in pneumatic device to transfer equipment in uncased boreholes. There are test results on the source prototype, amplitude and frequency characteristics and spectral content of the source signal.

  14. Carrier synchronization techniques for unbalanced QPSK signals. I

    NASA Technical Reports Server (NTRS)

    Braun, W. R.; Lindsey, W. C.

    1977-01-01

    This paper uses MAP estimation techniques to obtain carrier reconstruction circuits for unbalanced QPSK signals. In addition, the performance analysis of these circuits is carried out to the extent that a loop design can proceed. Numerical results are presented in order to demonstrate the utility of the theory developed. This signal design will be used in the development of the Tracking and Data Relay Satellite System (TDRSS) and the Navigation Satellite Timing and Ranging Global Positioning System (NAVSTAR GPS).

  15. Carrier synchronization techniques for unbalanced QPSK signals. II

    NASA Technical Reports Server (NTRS)

    Braun, W. R.; Lindsey, W. C.

    1977-01-01

    This paper develops a theory for assessing the tracking performance and designing carrier synchronization loops which are to be matched to an unbalanced QPSK signal design. It is assumed that the power split and the I and Q channel data rates are arbitrary. Bit synchronization is assumed to be unavailable for both carrier reconstruction techniques which have been suggested via MAP estimation theory. Numerical results are presented.

  16. On the longitudinal distribution of electric field in the acceleration zones of plasma accelerators and thrusters with closed electron drift

    NASA Astrophysics Data System (ADS)

    Kim, V. P.

    2017-04-01

    The long-term experience in controlling the electric field distribution in the discharge gaps of plasma accelerators and thrusters with closed electron drift and the key ideas determining the concepts of these devices and tendencies of their development are analyzed. It is shown that an electrostatic mechanism of ion acceleration in plasma by an uncompensated space charge of the cloud of magnetized electrons "kept" to the magnetic field takes place in the acceleration zones and that the electric field distribution can be controlled by varying the magnetic field in the discharge gap. The role played by the space charge makes the mechanism of ion acceleration in this type of thrusters is fundamentally different from the acceleration mechanism operating in purely electrostatic thrusters.

  17. Mapping the open/closed boundary in Jupiter’s polar cap with a 2-D equatorial magnetic field model

    NASA Astrophysics Data System (ADS)

    Vogt, M. F.; Kivelson, M. G.; Khurana, K. K.; Walker, R. J.

    2009-12-01

    The main auroral oval emissions at Jupiter are not associated with the open/closed flux boundary in the polar cap as they are at the Earth, but with the breakdown of plasma corotation in the middle magnetosphere. As a result, the boundary between open and closed flux in the ionosphere is not well defined, though the region of open flux is generally thought to be small. We have mapped contours of constant radial distance from the magnetic equator to the ionosphere with the objective of understanding how auroral features relate to magnetospheric sources. Instead of following along a model field, we map equatorial field lines to the ionosphere by requiring that the magnetic flux in some specified region at the equator equal the magnetic flux in the area to which it maps in the ionosphere. We represent the north-south component of the measured magnetic field (Bθ) at the equator as a function of radial distance and local time by fitting equatorial field measurements to a two-dimensional functional form. From the equatorial field function, we calculate the flux through the equator in pixels of radial increment 5 RJ and a fixed longitudinal. We start by identifying the ionospheric footprint of an equatorial curve at 20 RJ where field models are reasonably accurate. The pixels at 20 RJ are traced to the ionosphere using the field bend back from Khurana and Schwarzl (2005) to determine the corresponding surface longitude. Using a version of the VIP4 model (Connerney et al., 1998) that has been modified to include the effects of the current sheet (Khurana, 1997) to estimate the internal Jovian field in the ionosphere, we then displace the auroral boundary poleward until the ionospheric flux equals the flux in the equatorial pixel. With iteration, we obtain the ionospheric mapping of the 25 RJ circle at the equator. Further iteration provides the mapping of successively distant circles. Equating the fluxes in this way allows us to link a given position in the magnetosphere

  18. Laser intensity determination using nonadiabatic tunneling ionization of atoms in close-to-circularly polarized laser fields.

    PubMed

    Quan, Wei; Yuan, MingHu; Yu, ShaoGang; Xu, SongPo; Chen, YongJu; Wang, YanLan; Sun, RenPing; Xiao, ZhiLei; Gong, Cheng; Hua, LinQiang; Lai, XuanYang; Liu, XiaoJun; Chen, Jing

    2016-10-03

    We conceive an improved procedure to determine the laser intensity with the momentum distributions from nonadiabatic tunneling ionization of atoms in the close-to-circularly polarized laser fields. The measurements for several noble gas atoms are in accordance with the semiclassical calculations, where the nonadiabatic effect and the influence of Coulomb potential are included. Furthermore, the high-order above-threshold ionization spectrum in linearly polarized laser fields for Ar is measured and compared with the numerical calculation of the time-dependent Schrödinger equation in the single-active-electron approximation to test the accuracy of the calibrated laser intensity.

  19. The mathematical models of electromagnetic field dynamics and heat transfer in closed electrical contacts including Thomson effect

    NASA Astrophysics Data System (ADS)

    Kharin, Stanislav; Sarsengeldin, Merey; Kassabek, Samat

    2016-08-01

    We represent mathematical models of electromagnetic field dynamics and heat transfer in closed symmetric and asymmetric electrical contacts including Thomson effect, which are essentially nonlinear due to the dependence of thermal and electrical conductivities on temperature. Suggested solutions are based on the assumption of identity of equipotentials and isothermal surfaces, which agrees with experimental data and valid for both linear and nonlinear cases. Well known Kohlrausch temperature-potential relation is analytically justified.

  20. Three-Phase Load Flow for Unbalanced Systems.

    NASA Astrophysics Data System (ADS)

    Chang, Yih-Ping

    Traditionally, transmission systems are assumed to be balanced in power system analysis. A single phase positive sequence circuit is used in transmission system load flow analysis to simplify the study. However, when untransposed transmission lines are used in a power system due to economic considerations, space limitation; or when large unbalanced load is on the system; or when an unbalance contingency occurs on the system, this assumption may not hold true. The unbalance condition in some isolated systems are so precarious that disaster can result. One such incident occurred on a generator unit of the third nuclear power plant of Taipower in 1985. In that particular case, the turbine blades were broken and a spark ignited the liquid hydrogen when the blade vibration resonated with the 120.5 Hz rotor current. One cause of this rotor current generation is system unbalance. The unbalanced three-phase load flow program is needed in today's power system analysis. An advanced three-phase unbalanced transmission load flow program, capable of locating the unbalanced problem of large electric network systems, was proposed to be developed and tested in this research. Features of this program include simultaneous power flow of multiple voltage levels on an individual phase basis; PV bus generator, cogenerator, transformer simulation, and load modeling. It is found that delta-grounded wye step-up transformer reduces the convergence speed greatly. When too many delta-grounded wye step-up transformers exist in a large scale system and a quick approximate result of the unbalance conditions is needed, these step-up transformers can be substituted by grounded-wye to grounded-wye type transformers. This is tested on a Taipower system case which included 345KV, 161KV and 69KV feeders, network transformers, 34 PV bus generators and 188 three-phase buses. Impending unbalance problems in Taipower system were located. When not too many delta-grounded wye type transformers are in the

  1. Close-range photogrammetry with light field camera: from disparity map to absolute distance.

    PubMed

    Yang, Peng; Wang, Zhaomin; Yan, Yizhen; Qu, Weijuan; Zhao, Hongying; Asundi, Anand; Yan, Lei

    2016-09-20

    A new approach to measure the 3D profile of a texture object is proposed utilizing light field imaging, in which three key steps are required: a disparity map is first obtained by detecting the slopes in the epipolar plane image with the multilabel technique; the intrinsic parameters of the light field camera are then extracted by camera calibration; at last, the relationship between disparity values and real distances is built up by depth calibration. In the last step, a linear calibration method is proposed to achieve accurate results. Furthermore, the depth error is also investigated and compensated for by reusing the checkerboard pattern. The experimental results are in good agreement with the 3D models, and also indicate that the light field imaging is a promising 3D measurement technique.

  2. Real-space observation of unbalanced charge distribution inside a perovskite-sensitized solar cell.

    PubMed

    Bergmann, Victor W; Weber, Stefan A L; Javier Ramos, F; Nazeeruddin, Mohammad Khaja; Grätzel, Michael; Li, Dan; Domanski, Anna L; Lieberwirth, Ingo; Ahmad, Shahzada; Berger, Rüdiger

    2014-09-22

    Perovskite-sensitized solar cells have reached power conversion efficiencies comparable to commercially available solar cells used for example in solar farms. In contrast to silicon solar cells, perovskite-sensitized solar cells can be made by solution processes from inexpensive materials. The power conversion efficiency of these cells depends substantially on the charge transfer at interfaces. Here we use Kelvin probe force microscopy to study the real-space cross-sectional distribution of the internal potential within high efficiency mesoscopic methylammonium lead tri-iodide solar cells. We show that the electric field is homogeneous through these devices, similar to that of a p-i-n type junction. On illumination under short-circuit conditions, holes accumulate in front of the hole-transport layer as a consequence of unbalanced charge transport in the device. After light illumination, we find that trapped charges remain inside the active device layers. Removing these traps and the unbalanced charge injection could enable further improvements in performance of perovskite-sensitized solar cells.

  3. Magnetic field driven ambipolar quantum Hall effect in epitaxial graphene close to the charge neutrality point

    NASA Astrophysics Data System (ADS)

    Nachawaty, A.; Yang, M.; Desrat, W.; Nanot, S.; Jabakhanji, B.; Kazazis, D.; Yakimova, R.; Cresti, A.; Escoffier, W.; Jouault, B.

    2017-08-01

    We have investigated the disorder of epitaxial graphene close to the charge neutrality point (CNP) by various methods: (i) at room temperature, by analyzing the dependence of the resistivity on the Hall coefficient; (ii) by fitting the temperature dependence of the Hall coefficient down to liquid helium temperature; (iii) by fitting the magnetoresistances at low temperature. All methods converge to give a disorder amplitude of (20 ±10 ) meV. Because of this relatively low disorder, close to the CNP, at low temperature, the sample resistivity does not exhibit the standard value ≃h /4 e2 but diverges. Moreover, the magnetoresistance curves have a unique ambipolar behavior, which has been systematically observed for all studied samples. This is a signature of both asymmetry in the density of states and in-plane charge transfer. The microscopic origin of this behavior cannot be unambiguously determined. However, we propose a model in which the SiC substrate steps qualitatively explain the ambipolar behavior.

  4. Closed-loop torque feedback for a universal field-oriented controller

    DOEpatents

    De Doncker, R.W.A.A.; King, R.D.; Sanza, P.C.; Haefner, K.B.

    1992-11-24

    A torque feedback system is employed in a universal field-oriented (UFO) controller to tune a torque-producing current command and a slip frequency command in order to achieve robust torque control of an induction machine even in the event of current regulator errors and during transitions between pulse width modulated (PWM) and square wave modes of operation. 1 figure.

  5. Closed-loop torque feedback for a universal field-oriented controller

    SciTech Connect

    De Doncker, R.W.A.A.; King, R.D.; Sanza, P.C.; Haefner, K.B.

    1992-11-24

    A torque feedback system is employed in a universal field-oriented (UFO) controller to tune a torque-producing current command and a slip frequency command in order to achieve robust torque control of an induction machine even in the event of current regulator errors and during transitions between pulse width modulated (PWM) and square wave modes of operation. 1 figure.

  6. Closing the superconducting gap in small Pb nanoislands with high magnetic fields

    NASA Astrophysics Data System (ADS)

    Rolf-Pissarczyk, Steffen; Burgess, Jacob A. J.; Yan, Shichao; Loth, Sebastian

    2016-12-01

    Superconducting properties change in confined geometries. Here we study the effects of strong confinement in nanosized Pb islands on Si(111) 7 ×7 . Small hexagonal islands with diameters less than 50 nm and a uniform height of seven atomic layers are formed by depositing Pb at low temperature and annealing at 300 K. We measure the tunneling spectra of individual Pb nanoislands using a low-temperature scanning tunneling microscope operated at 0.6 K and follow the narrowing of the superconducting gap as a function of magnetic field. We find the critical magnetic field, at which the superconducting gap vanishes, reaches several Tesla, which represents a greater than 50-fold enhancement compared to the bulk value. By independently measuring the size of the superconducting gap, and the critical magnetic field that quenches superconductivity for a range of nanoislands, we can correlate these two fundamental parameters and estimate the maximal achievable critical field for 7 ML Pb nanoislands to be 7 T.

  7. Closed-loop torque feedback for a universal field-oriented controller

    DOEpatents

    De Doncker, Rik W. A. A.; King, Robert D.; Sanza, Peter C.; Haefner, Kenneth B.

    1992-01-01

    A torque feedback system is employed in a universal field-oriented (UFO) controller to tune a torque-producing current command and a slip frequency command in order to achieve robust torque control of an induction machine even in the event of current regulator errors and during transitions between pulse width modulated (PWM) and square wave modes of operation.

  8. Optimal Voltage Regulation for Unbalanced Distribution Networks Considering Distributed Energy Resources

    SciTech Connect

    Xu, Yan; Tomsovic, Kevin

    2015-01-01

    With increasing penetration of distributed generation in the distribution networks (DN), the secure and optimal operation of DN has become an important concern. In this paper, an iterative quadratic constrained quadratic programming model to minimize voltage deviations and maximize distributed energy resource (DER) active power output in a three phase unbalanced distribution system is developed. The optimization model is based on the linearized sensitivity coefficients between controlled variables (e.g., node voltages) and control variables (e.g., real and reactive power injections of DERs). To avoid the oscillation of solution when it is close to the optimum, a golden search method is introduced to control the step size. Numerical simulations on modified IEEE 13 nodes test feeders show the efficiency of the proposed model. Compared to the results solved by heuristic search (harmony algorithm), the proposed model converges quickly to the global optimum.

  9. Tunable Lattice Coupling of Multipole Plasmon Modes and Near-Field Enhancement in Closely Spaced Gold Nanorod Arrays

    PubMed Central

    Huang, Yu; Zhang, Xian; Ringe, Emilie; Hou, Mengjing; Ma, Lingwei; Zhang, Zhengjun

    2016-01-01

    Considering the nanogap and lattice effects, there is an attractive structure in plasmonics: closely spaced metallic nanoarrays. In this work, we demonstrate experimentally and theoretically the lattice coupling of multipole plasmon modes for closely spaced gold nanorod arrays, offering a new insight into the higher order cavity modes coupled with each other in the lattice. The resonances can be greatly tuned by changes in inter-rod gaps and nanorod heights while the influence of the nanorod diameter is relatively insignificant. Experimentally, pronounced suppressions of the reflectance are observed. Meanwhile, the near-field enhancement can be further enhanced, as demonstrated through surface enhanced Raman scattering (SERS). We then confirm the correlation between the near-field and far-field plasmonic responses, which is significantly important for maximizing the near-field enhancement at a specific excitation wavelength. This lattice coupling of multipole plasmon modes is of broad interest not only for SERS but also for other plasmonic applications, such as subwavelength imaging or metamaterials. PMID:26983501

  10. Closing of the Midcontinent-Rift - a far-field effect on Grenvillian compression

    USGS Publications Warehouse

    Cannon, W.F.

    1994-01-01

    The Midcontinent rift formed in the Laurentian supercontinent between 1109 and 1094 Ma. Soon after rifting, stresses changed from extensional to compressional, and the central graben of the rift was partly inverted by thrusting on original extensional faults. Thrusting culminated at about 1060 Ma but may have begun as early as 1080 Ma. On the southwest-trending arm of the rift, the crust was shortened about 30km; on the southeast-trending arm, strike-slip motion was dominant. The rift developed adjacent to the tectonically active Grenville province, and its rapid evolution from an extensional to a compressional feature at c1080 Ma was coincident with renewal of northwest-directed thrusting in the Grenville, probably caused by continent-continent collision. A zone of weak lithosphere created by rifting became the locus for deformation within the otherwise strong continental lithosphere. Stresses transmitted from the Grenville province utilized this weak zone to close and invert the rift. -Author

  11. African crop yield reductions due to increasingly unbalanced Nitrogen and Phosphorus consumption.

    PubMed

    van der Velde, Marijn; Folberth, Christian; Balkovič, Juraj; Ciais, Philippe; Fritz, Steffen; Janssens, Ivan A; Obersteiner, Michael; See, Linda; Skalský, Rastislav; Xiong, Wei; Peñuelas, Josep

    2014-04-01

    The impact of soil nutrient depletion on crop production has been known for decades, but robust assessments of the impact of increasingly unbalanced nitrogen (N) and phosphorus (P) application rates on crop production are lacking. Here, we use crop response functions based on 741 FAO maize crop trials and EPIC crop modeling across Africa to examine maize yield deficits resulting from unbalanced N : P applications under low, medium, and high input scenarios, for past (1975), current, and future N : P mass ratios of respectively, 1 : 0.29, 1 : 0.15, and 1 : 0.05. At low N inputs (10 kg ha(-1)), current yield deficits amount to 10% but will increase up to 27% under the assumed future N : P ratio, while at medium N inputs (50 kg N ha(-1)), future yield losses could amount to over 40%. The EPIC crop model was then used to simulate maize yields across Africa. The model results showed relative median future yield reductions at low N inputs of 40%, and 50% at medium and high inputs, albeit with large spatial variability. Dominant low-quality soils such as Ferralsols, which are strongly adsorbing P, and Arenosols with a low nutrient retention capacity, are associated with a strong yield decline, although Arenosols show very variable crop yield losses at low inputs. Optimal N : P ratios, i.e. those where the lowest amount of applied P produces the highest yield (given N input) where calculated with EPIC to be as low as 1 : 0.5. Finally, we estimated the additional P required given current N inputs, and given N inputs that would allow Africa to close yield gaps (ca. 70%). At current N inputs, P consumption would have to increase 2.3-fold to be optimal, and to increase 11.7-fold to close yield gaps. The P demand to overcome these yield deficits would provide a significant additional pressure on current global extraction of P resources.

  12. Numerical field model simulation of full scale fire tests in a closed spherical/cylindrical vessel

    NASA Astrophysics Data System (ADS)

    Raycraft, Janet K.

    1987-12-01

    Most of the casualties incurred during a fire are due to the smoke generated. An understanding of the way smoke and fire spread during a fire would provide a valuable tool to save lives and minimize damage. The Naval Research Laboratory maintains a full scale test facility called Fire-1. The computer model developed in this thesis is based on the actual geometry of Fire-1 and uses field modeling. It is a three dimensional, finite difference model using primitive variables. The model includes local and global pressure corrections, surface radiation, turbulence, strong buoyancy, and conjugate boundary conditions. Given heat input data, the computer code produces pressure, temperature, density, and velocity fields. Experimental fire tests conducted in Fire-1 are used to validate the computer code. Reasonable agreement in the results has been found. Because of the model's ability to account for pressure, temperature and smoke buildup, its envisioned use is to predict fires aboard ships and submarines.

  13. Liquid Metal-Wetted Niobium Fiber Brushes and Braid Close Clearance Collectors in Magnetic Fields Comparison

    DTIC Science & Technology

    1993-08-01

    300-kW homopolar generator. Collector rip velocities varied from zero to 67 m/sec, currents from zero to 4,000 A, and magnetic fields from zero to 1.2...collectors is highly desirable because it makes the implementation of homopolar machinery attractive for a variety of applica- tions.’ Liquid metals can...current collector is its operation in an electrical machine. The collectors described here will be operated in a 300-kW superconducting homopolar

  14. Experiment close out of lysimeter field testing of low-level radioactive waste forms

    SciTech Connect

    McConnell, J.W. Jr.; Rogers, R.D.; Jastrow, J.D.

    1998-03-01

    The Field Lysimeter Investigations: Low-Level Waste Data Base Development Program is obtaining information on the performance of radioactive waste forms. These experiments were recently shut down and the contents of the lysimeters have been examined in accordance with a detailed waste form and soil sampling plan. Ion-exchange resins from a commercial nuclear power station were solidified into waste forms using portland cement and vinyl ester-styrene. These waste forms were tested to (a) obtain information on performance of waste forms in typical disposal environments, (b) compare field results with bench leach studies, (c) develop a low-level waste data base for use in performance assessment source term calculations, and (d) apply the DUST computer code to compare predicted cumulative release to actual field data. The program, funded by the Nuclear Regulatory Commission (NRC), includes observed radio nuclide releases from waste forms in field lysimeters at two test sites over 10 years of successful operation. The purpose of this paper is to present the results of the examination of waste forms and soils of the two lysimeter arrays after shut down. During this examination, the waste forms were characterized after removal from the lysimeters and the results compared to the findings of the original characterizations. Vertical soil cores were taken from the soil columns and analyzed with radiochemistry to define movement of radionuclides in the soils after release from the waste forms. A comparison is made of the DUST and BLT code predictions of releases and movement, using recently developed partition coefficients and leachate measurements, to actual radio nuclide movement through the soil columns as determined from these core analyses.

  15. Excitation of plasma waves by unstable photoelectron and thermal electron populations on closed magnetic field lines in the Martian ionosphere

    NASA Astrophysics Data System (ADS)

    Borisov, N.; Nielsen, E.

    2005-06-01

    It is argued that anisotropic electron pitch angle distributions in the closed magnetic field regions of the Martian ionosphere gives rise to excitation of plasma instabilities. We discuss two types of instabilities that are excited by two different populations of electrons. First, the generation of Langmuir waves by photoelectrons with energies of the order of 10eV is investigated. It is predicted that the measured anisotropy of their pitch angle distribution at the heights z≍400km causes excitation of waves with frequencies f~30kHz and wavelengths λ~30m. Near the terminators the instability of the electrostatic waves with frequencies of the order of or less than the electron gyrofrequency exited by thermal electrons is predicted. The typical frequencies of these waves depend on the local magnitude of the magnetic field and can achieve values f~3-5kHz above strong crustal magnetic fields.

  16. Electric Mars: A large trans-terminator electric potential drop on closed magnetic field lines above Utopia Planitia

    NASA Astrophysics Data System (ADS)

    Collinson, Glyn; Mitchell, David; Xu, Shaosui; Glocer, Alex; Grebowsky, Joseph; Hara, Takuya; Lillis, Robert; Espley, Jared; Mazelle, Christian; Sauvaud, Jean-André; Fedorov, Andrey; Liemohn, Mike; Andersson, Laila; Jakosky, Bruce

    2017-02-01

    Parallel electric fields and their associated electric potential structures play a crucial role in ionospheric-magnetospheric interactions at any planet. Although there is abundant evidence that parallel electric fields play key roles in Martian ionospheric outflow and auroral electron acceleration, the fields themselves are challenging to directly measure due to their relatively weak nature. Using measurements by the Solar Wind Electron Analyzer instrument aboard the NASA Mars Atmosphere and Volatile EvolutioN (MAVEN) Mars Scout, we present the discovery and measurement of a substantial (ΦMars=7.7 ± 0.6 V) parallel electric potential drop on closed magnetic field lines spanning the terminator from day to night above the great impact basin of Utopia Planitia, a region largely free of crustal magnetic fields. A survey of the previous 26 orbits passing over a range of longitudes revealed similar signatures on seven orbits, with a mean potential drop (ΦMars) of 10.9 ± 0.8 V, suggestive that although trans-terminator electric fields of comparable strength are not ubiquitous, they may be common, at least at these northerly latitudes.

  17. Electric Mars: A Large Trans-Terminator Electric Potential Drop on Closed Magnetic Field Lines Above Utopia Planitia

    NASA Technical Reports Server (NTRS)

    Collinson, Glyn; Mitchell, David; Xu, Shaosui; Glocer, Alex; Grebowsky, Joseph; Hara, Takuya; Lillis, Robert; Espley, Jared; Mazelle, Christian; Sauvaud, Jean-Andre

    2017-01-01

    Abstract Parallel electric fields and their associated electric potential structures play a crucial role inionospheric-magnetospheric interactions at any planet. Although there is abundant evidence that parallel electric fields play key roles in Martian ionospheric outflow and auroral electron acceleration, the fields themselves are challenging to directly measure due to their relatively weak nature. Using measurements by the Solar Wind Electron Analyzer instrument aboard the NASA Mars Atmosphere and Volatile EvolutioN(MAVEN) Mars Scout, we present the discovery and measurement of a substantial (Phi) Mars 7.7 +/-0.6 V) parallel electric potential drop on closed magnetic field lines spanning the terminator from day to night above the great impact basin of Utopia Planitia, a region largely free of crustal magnetic fields. A survey of the previous 26 orbits passing over a range of longitudes revealed similar signatures on seven orbits, with a mean potential drop (Phi) Mars of 10.9 +/- 0.8 V, suggestive that although trans-terminator electric fields of comparable strength are not ubiquitous, they may be common, at least at these northerly latitudes.

  18. Properties of net ionospheric currents closing field-aligned currents in the auroral region

    NASA Astrophysics Data System (ADS)

    Lühr, Hermann; Zhou, Yun-Liang

    2017-04-01

    Satellite missions offer the opportunity to deduce the net electric current flowing through the orbital loop. Suzuki and Fukushima [1982] were the first to apply Ampère's integral law to the along-track magnetic field component from the Magsat satellite. By utilizing the vector magnetic field measurements from CHAMP during 2001-2005, the characteristics of the net auroral currents calculated in this way are comprehensively investigated. It is found that the net currents deduced from noon-midnight (dawn-dusk) orbits are directed duskward (anti-sunward). The intensities of the net currents increase linearly when the merging electric field (Em) at the magnetopause is growing, exhibiting values of about 2 (1) MA for the net duskward (anti-sunward) currents when Em exceeds 4 mV/m. For the first time the seasonal variations of the different net currents are derived. The net currents deduced from full orbits show only little seasonal dependence due to a compensation of the effects between the hemispheres. Conversely, the net currents deduced separately for the two hemispheres exhibit prominent seasonal dependences. For the net duskward currents the amplitudes are larger by a factor of about 2 in summer than in winter. The related cross-polar cap Pedersen currents are higher in the sunlit hemisphere due to enhanced conductivity. Conversely, the net anti-sunward currents (mainly Hall currents) show an opposite seasonal dependence. The ratio of summer-to-winter intensity amounts to about 0.6. In this case the conductivity gradient from the auroral oval to the polar cap is of importance, which is larger in winter.

  19. Closed-loop field conjugation using decentralized multi-conjugate adaptive optics

    NASA Astrophysics Data System (ADS)

    Lee, Lawton H.

    2007-04-01

    Imaging through turbulence using adaptive optics is limited by scintillation, even with perfect wavefront sensing and reconstruction. Such errors can be mitigated in closed loop by multi-conjugate adaptive optics systems consisting of two phase correctors, each of which is driven by a pair of wavefront sensor phase measurements, along with an internal probe beam that samples the beam train along a common path while propagating in the opposite direction as the external signal beam or beacon wavefront that samples the turbulence. With this arrangement, not only direct measurement and feedback of irradiance but also intensive and/or highly coupled nonlinear control algorithms can be avoided in favor of more conventional, simple, decentralized linear control laws. Linear stability analysis of such systems is feasible in spatial frequency domain, and nonlinear wave-optic simulations in time domain suggest that, given sufficient temporal bandwidth, rejection of combined phase and amplitude disturbances can be enhanced by a factor of two or more (as quantified by error variances or Strehl ratio logarithms). Previous studies by other authors are extended using simplified regularization methods.

  20. Poly-β-Hydroxybutyrate Accumulation as a Measure of Unbalanced Growth of the Estuarine Detrital Microbiota †

    PubMed Central

    Nickels, Janet S.; King, John D.; White, David C.

    1979-01-01

    The procaryotic endogenous storage material poly-β-hydroxybutyrate (PHB) can be induced to accumulate in the estuarine detrital microbiota under conditions which suggest unbalanced growth, such as limitation of a critical factor(s) in the presence of carbon and energy sources. Changes in PHB-to-lipid phosphate ratios detected in field samples can be mimicked in the laboratory with common estuarine stresses. Acute anoxia or low pH induces conditions of no growth with depression of both the synthesis and catabolism of PHB without change in the lipid phosphate. Balanced growth induced by nutrients increases the lipid phosphate, depresses PHB synthesis, and stimulates PHB catabolism, resulting in a low ratio of PHB to lipid phosphate. Unbalanced growth induced to a small extent by high salinity or much more readily by dark upland runoff water results in rapid accumulation of PHB and slowing of PHB catabolism with little change in lipid phospate. Unbalanced growth conditions result in high PHB-to-lipid phosphate ratios in the detrital microbiota. PMID:16345354

  1. Net ionospheric currents closing field-aligned currents in the auroral region: CHAMP results

    NASA Astrophysics Data System (ADS)

    Zhou, Yun-Liang; Lühr, Hermann

    2017-04-01

    By utilizing the high-resolution and precise vector magnetic field measurements from CHAMP during 2001-2005, the characteristics of the net auroral currents calculated by Ampère's integral law are comprehensively investigated. It is found that the net currents deduced from noon-midnight (dawn-dusk) orbits are directed duskward (antisunward). The intensities of the net currents increase linearly when the merging electric field (Em) is growing, exhibiting maximum values of about 2 (1) MA for the net duskward (antisunward) currents when Em exceeds 4 mV/m. For the first time the seasonal variations of the different net currents are shown. The net currents deduced from full orbits show only little seasonal dependence due to a compensation of the effects between the hemispheres. Conversely, the net currents deduced separately for the two hemispheres exhibit prominent seasonal dependences. For the net duskward currents the amplitudes and slopes of Em dependence are both larger by a factor of about 2 in summer than in winter. The related cross-polar cap Pedersen currents are higher in the sunlit hemisphere due to enhanced conductivity. The summer-time duskward currents are larger in the Northern Hemisphere than in the Southern Hemisphere by a factor of 1.5. Conversely, the net antisunward currents show an opposite seasonal dependence. The ratio of summer to winter intensity amounts to about 0.7. In this case the currents are stronger in the Southern Hemisphere.

  2. A Multipactor Discharge in Crossed Fields Under the Conditions of a Combination of Two Waves with Close Frequencies

    NASA Astrophysics Data System (ADS)

    Ilyakov, E. V.; Kulagin, I. S.

    2013-09-01

    We study the multipactor discharge in crossed fields, specifically, a microwave electric field and a quasistatic magnetic field. The multipactor occurs under the conditions of superposition of two microwave pulses with close frequencies, which correspond to the three-centimeter wavelength range. Experiments in the rectangular waveguide demonstrate that the multipactor develops and exists in a wide range of differences in the signal frequencies, which covers on interval of up to 700 MHz. The specific power absorbed in the discharge is equal to several kW/cm2, and the radiation is absorbed efficiently at both frequencies. When the signal power is initially insufficient to ensure the multipactor development, an additional signal at a close frequency allows one to switch the discharge, which absorbs microwaves efficiently, on and off. At a frequency difference of up to 40 MHz, the achieved switch-on time is about 100 ns. Switch-on of the second signal in the line with a resonator cavity, which has a frequency belonging to the cavity frequency band, also results in the discharge development and switches the cavity from the transition regime to the reflection regime.

  3. Field evaluation of open and closed-path CO2 flux systems over asphalt surface

    NASA Astrophysics Data System (ADS)

    Bogoev, I.; Santos, E.

    2016-12-01

    Eddy covariance (EC) is a widely used method for quantifying surface fluxes of heat, water vapor and carbon dioxide between ecosystems and the atmosphere. A typical EC system consists of an ultrasonic anemometer measuring the 3D wind vector and a fast-response infrared gas analyzer for sensing the water vapor and CO2 density in the air. When using an open-path analyzer that detects the constituent's density in situ a correction for concurrent air temperature and humidity fluctuations must be applied, Webb et al. (1980). In environments with small magnitudes of CO2 flux (<5µmol m-2 s-1) and in the presence of high sensible heat flux, like wintertime over boreal forest, open-path flux measurements have been challenging since the magnitude of the density corrections are as large as the uncorrected CO2 flux itself. A new technology merging the sensing paths of the gas analyzer and the sonic anemometer has been recently developed. This new integrated instrument allows a direct measurement of CO2 mixing ratio in the open air and has the potential to improve the quality of the temperature related density corrections by synchronously measuring the sensible heat flux in the optical path of the gas analyzer. We evaluate the performance and the accuracy of this new sensor over a large parking lot with an asphalt surface where the CO2 fluxes are considered low and the interfering sensible heat fluxes are above 200 Wm-2. A co-located closed-path EC system is used as a reference measurement to examine any systematic biases and apparent CO2 uptake observed with open-path sensors under high sensible heat flux regimes. Half-hour mean and variance of CO2 and water vapor concentrations are evaluated. The relative spectral responses, covariances and corrected turbulent fluxes using a common sonic anemometer are analyzed. The influence of sensor separation and frequency response attenuation on the density corrections is discussed.

  4. Inter- and intra-guild interactions related to aphids in nettle (Urtica dioica L.) strips closed to field crops.

    PubMed

    Alhmedi, A; Haubruge, E; Bodson, B; Francis, F

    2006-01-01

    A field experiment designed to assess the biodiversity related to nettle strips closed to crops, and more particularly the aphid and related beneficial populations, was established in experimental farm located in Gembloux (Belgium). Margin strips of nettle (Urtica dioica) closed to wheat (Triticum aestivum), green pea (Pisum sativum) and rape (Brassicae napus) fields were investigated. The diversity, abundance of aphids and related predators were analysed according to the plant crop species and the differential pesticide application (treated plot and control). Insects were visually observed every week during all the cultivation season. Two main families of aphidophagous predators were found in all field crops and nettle, the Coccinellidae and Syrphidae. The diversity of the aphidophagous predators was shown to be higher on nettle than in field crops, particularly the Chrysopidae, the Anthocoridae and the Miridae. However, a striking difference of ladybird abundance was observed according to the aphid host plant. In one side, Coccinella septempunctata was much more abundant on Acyrthosiphon pisum infested green pea than on the other host plant species. At the opposite, higher occurrence of Harmonia axyridis was observed on the aphid infested nettle plants than on the crop plants. In particular, none of H. axyridis was found in wheat crop. Also, more than only a significant positive correlation between predator and aphid abundance, specialised relations between particular aphid species and some so-called generalist predators was determined in the fields. Finally, intraguild interactions between the aphidophagous predators was assessed and shown that only a significant negative correlation between Episyrphus balteatus and H. axyridis related to the nettle aphid, Micrlophium carnosum, was observed. The relative distribution of the ladybirds, namely C. septempunctata and H. axyridis according to the host plant, nettle strips and crop plots was discussed in relation to

  5. Unbalanced translocations arise from diverse mutational mechanisms including chromothripsis.

    PubMed

    Weckselblatt, Brooke; Hermetz, Karen E; Rudd, M Katharine

    2015-07-01

    Unbalanced translocations are a relatively common type of copy number variation and a major contributor to neurodevelopmental disorders. We analyzed the breakpoints of 57 unique unbalanced translocations to investigate the mechanisms of how they form. Fifty-one are simple unbalanced translocations between two different chromosome ends, and six rearrangements have more than three breakpoints involving two to five chromosomes. Sequencing 37 breakpoint junctions revealed that simple translocations have between 0 and 4 base pairs (bp) of microhomology (n = 26), short inserted sequences (n = 8), or paralogous repeats (n = 3) at the junctions, indicating that translocations do not arise primarily from nonallelic homologous recombination but instead form most often via nonhomologous end joining or microhomology-mediated break-induced replication. Three simple translocations fuse genes that are predicted to produce in-frame transcripts of SIRPG-WWOX, SMOC2-PROX1, and PIEZO2-MTA1, which may lead to gain of function. Three complex translocations have inversions, insertions, and multiple breakpoint junctions between only two chromosomes. Whole-genome sequencing and fluorescence in situ hybridization analysis of two de novo translocations revealed at least 18 and 33 breakpoints involving five different chromosomes. Breakpoint sequencing of one maternally inherited translocation involving four chromosomes uncovered multiple breakpoints with inversions and insertions. All of these breakpoint junctions had 0-4 bp of microhomology consistent with chromothripsis, and both de novo events occurred on paternal alleles. Together with other studies, these data suggest that germline chromothripsis arises in the paternal genome and may be transmitted maternally. Breakpoint sequencing of our large collection of chromosome rearrangements provides a comprehensive analysis of the molecular mechanisms behind translocation formation. © 2015 Weckselblatt et al.; Published by Cold Spring Harbor

  6. The dayside open/closed field line boundary as seen from space- and ground-based instrumentation

    NASA Astrophysics Data System (ADS)

    Johnsen, M. G.; Lorentzen, D. A.

    2012-03-01

    In this paper we validate the method of Johnsen et al. (2012) for obtaining the cusp open/closed field line boundary (OCB) by the means of a single meridian scanning photometer (MSP). Three cases of conjugate measurements between the Longyearbyen MSP and the NOAA-16 satellite are presented. The satellite OCB as obtained by the energetic particle detectors carried onboard the NOAA-16 satellite is well co-located with the OCB as obtained by the ground-based MSP and well within the calculated uncertainties. We conclude that the method presented by Johnsen et al. (2012) for deriving the cusp OCB using a single MSP produces conscientious results.

  7. Hamiltonian structure of Dubrovin{close_quote}s equation of associativity in 2-d topological field theory

    SciTech Connect

    Galvao, C.A.; Nutku, Y.

    1996-12-01

    mA third order Monge-Amp{grave e}re type equation of associativity that Dubrovin has obtained in 2-d topological field theory is formulated in terms of a variational principle subject to second class constraints. Using Dirac{close_quote}s theory of constraints this degenerate Lagrangian system is cast into Hamiltonian form and the Hamiltonian operator is obtained from the Dirac bracket. There is a new type of Kac-Moody algebra that corresponds to this Hamiltonian operator. In particular, it is not a W-algebra. {copyright} {ital 1996 American Institute of Physics.}

  8. Field study of nitrous oxide production with in situ aeration in a closed landfill site.

    PubMed

    Nag, Mitali; Shimaoka, Takayuki; Nakayama, Hirofumi; Komiya, Teppei; Xiaoli, Chai

    2016-03-01

    Nitrous oxide (N(2)O) has gained considerable attention as a contributor to global warming and depilation of stratospheric ozone layer. Landfill is one of the high emitters of greenhouse gas such as methane and N(2)O during the biodegradation of solid waste. Landfill aeration has been attracted increasing attention worldwide for fast, controlled and sustainable conversion of landfills into a biological stabilized condition, however landfill aeration impel N(2)O emission with ammonia removal. N(2)O originates from the biodegradation, or the combustion of nitrogen-containing solid waste during the microbial process of nitrification and denitrification. During these two processes, formation of N(2)O as a by-product from nitrification, or as an intermediate product of denitrification. In this study, air was injected into a closed landfill site and investigated the major N(2)O production factors and correlations established between them. The in-situ aeration experiment was carried out by three sets of gas collection pipes along with temperature probes were installed at three different distances of one, two and three meter away from the aeration point; named points A-C, respectively. Each set of pipes consisted of three different pipes at three different depths of 0.0, 0.75 and 1.5 m from the bottom of the cover soil. Landfill gases composition was monitored weekly and gas samples were collected for analysis of nitrous oxide concentrations. It was evaluated that temperatures within the range of 30-40°C with high oxygen content led to higher generation of nitrous oxide with high aeration rate. Lower O(2) content can infuse N(2)O production during nitrification and high O(2) inhibit denitrification which would affect N(2)O production. The findings provide insights concerning the production potentials of N(2)O in an aerated landfill that may help to minimize with appropriate control of the operational parameters and biological reactions of N turnover. Investigation of

  9. Permian {open_quotes}Wolfcamp{close_quotes} limestone reservoirs: Powell Ranch field, Eastern Midland Basin

    SciTech Connect

    Montgomery, S.L.

    1996-09-01

    Deep-water carbonate channel reservoirs form important oil reservoirs along the toe of the Eastern Shelf of the Permian basin in west Texas. In northwestern Glasscock County, these `Wolfcamp` reservoirs are Leonardian (Early Permian) in age and define high-energy channels incised into surrounding carbonate detritus and basinal shale. Porous grain-flow material filling these channels, along with encasing detritus, was derived from the shallow shelf located six miles to the east. Reservoirs are in packstone and grainstone facies and have significant interparticle and moldic porosity. Relevant exploration began in the 1960s, but expanded slowly thereafter due to lack of success caused by complex patterns of channel occurrence. Results of a three-dimensional (3-D) seismic survey conducted in 1990 have greatly enhanced the identification and mapping of productive channels in the Powell Ranch field complex. Wells in this complex are capable of flowing 400-1200 bbl of oil per day, and have reserves ranging from 0.2 to 1.3 MBO. The new 3-D data have improved the relevant geologic model and dramatically increased rates of drilling success. Application of such data to this setting offers a potential model for other parts of the Permian basin.

  10. A close-ridge small-scale atmospheric flow field and its influence on snow accumulation

    NASA Astrophysics Data System (ADS)

    Gerber, F.; Lehning, M.; Hoch, S. W.; Mott, R.

    2017-08-01

    The rough, steep, and complex terrain in the alpine environment causes a variety of flow patterns such as blocking, speed-up, or flow separation, which influence precipitation, snow deposition, and ultimately snow distribution on the ground. Cloud-terrain interactions, flow-particle interactions, and snow transport affect snow accumulation patterns, but the relative importance of these processes is not fully understood, in particular, in complex mountainous terrain. A unique combination of measurements and model simulations is used in a local case study during a 2 day snowfall event to demonstrate the current understanding of snow accumulation in very steep alpine terrain. Doppler wind lidar measurements show an eddy-like structure on the leeward side of the Sattelhorn ridge (in the Dischma valley near Davos, Switzerland), which could partly be replicated by Advanced Regional Prediction System (ARPS) flow simulations. Snow deposition measurements with a terrestrial laser scanner show a complex deposition pattern, which is only partially captured by Alpine3D deposition simulations driven by the ARPS flow fields. This shows that additional processes such as avalanches may play a role or that a more refined simulation of flow or flow-particle interactions is required to fully understand snow distribution in very steep mountainous terrain.

  11. Pc 3-4 Pulsations Near the Cusp: Latitude dependence near the open-closed field line boundary

    NASA Astrophysics Data System (ADS)

    Yeoman, T. K.; Wright, D. M.; Clausen, L. B.; Engebretson, M.; Lu, F.; Posch, J.; Lessard, M.; Kim, H.

    2008-12-01

    Dayside ground magnetometer records at high latitudes frequently show evidence of Pc 3-4 pulsations (f ~ 10-100 mHz) which originate in the ion foreshock upstream of the Earth's bow shock due to the interaction between reflected ions and the solar wind. Previous studies have noted increased Pc 3-4 wave power in the vicinity of the dayside cusp and inferred that the upstream waves gained entry via the cusp, although more recent studies have revealed a more complex picture. Here, we examine Pc3-4 wave power near local noon observed by search coil magnetometers at three closely-spaced stations on Svalbard. Three intervals are chosen when the upstream conditions are favourable for Pc3-4 generation, clear band-limited Pc3-4 wave power is observed near local noon, and an extended interval of HF radar backscatter indicative of the cusp is detected by the Hankasalmi SuperDARN radar. A stereo mode of radar operation is employed, such that 3 s time resolution is available on one radar beam, whilst the high latitude convection is revealed with 1 min. resolution. The location of the equatorward edge of the HF radar cusp may then be directly compared with the Pc3-4 wave power measured at three latitudes as the cusp migrates across the stations. The radar data show clear evidence of transient ionospheric flows and high spectral widths associated with field lines newly- opened by dayside reconnection processes, but no evidence of oscillations in the Pc3-4 frequency range. In the ground magnetic field a peak in Pc3-4 power is generally observed in the equatormost magnetometer, except when the cusp is significantly poleward of the stations, consistent with a peak in wave power ~4 degrees equatorward of the cusp, but suggesting a modest dependence of wave power with latitude on closed field lines When the cusp does move equatorward of the magnetometer stations the Pc3-4 power drops rapidly, and does so earliest at the most poleward magnetometer station, suggesting a sharp drop in

  12. Field Performance Verification of Carbon Dioxide, Water, and Nitrous Oxide Closed-Path Eddy Covariance Systems with Vortex Intakes

    NASA Astrophysics Data System (ADS)

    Burgon, R. P., Jr.; Sargent, S.; Zha, T.; Jia, X.

    2015-12-01

    Closed-path eddy covariance systems measure the flux of greenhouse gasses such as carbon dioxide, water vapor, and nitrous oxide. The challenge is to make accurate field measurements at sites around the world, even in extreme environmental conditions. Sites with dirty air present a particular challenge. Gas concentration measurements may be degraded as dust or debris is deposited on the optical windows in the sample cell. The traditional solution has been to add an in-line filter upstream of the sample cell to keep the windows clean. However, these filters clog over time and must be changed periodically. An in-line filter also acts as a mixing volume and in some cases limits the frequency response of the analyzer. A novel eddy-covariance system that includes a vortex air cleaner at the inlet has been developed and field tested. This new system eliminates the need for a traditional in-line filter to keep the sample cell windows clean. The new system reduces system maintenance and down time. Eddy covariance systems with the vortex intake were tested at several sites ranging from sites with extremely dirty urban air to sites with relatively clean mountain air, and in agricultural areas. These flux systems were monitoring either CO2 and H2O, or N2O. Results show that the closed-path eddy covariance systems with a vortex intake perform very well and require lower maintenance compared to similar systems with in-line filters.

  13. On the Effects of a Spacecraft Subcarrier Unbalanced Modulator

    NASA Technical Reports Server (NTRS)

    Nguyen, Tien Manh

    1993-01-01

    This paper presents mathematical models with associated analysis of the deleterious effects which a spacecraft's subcarrier unbalanced modulator has on the performance of a phase-modulated residual carrier communications link. The undesired spectral components produced by the phase and amplitude imbalances in the subcarrier modulator can cause (1) potential interference to the carrier tracking and (2) degradation in the telemetry bit signal-to-noise ratio (SNR). A suitable model for the unbalanced modulator is developed and the threshold levels of undesired components that fall into the carrier tracking loop are determined. The distribution of the carrier phase error caused by the additive White Gaussian noise (AWGN) and undesired component at the residual RF carrier is derived for the limiting cases. Further, this paper analyses the telemetry bit signal-to-noise ratio degradations due to undesirable spectral components as well as the carrier tracking phase error induced by phase and amplitude imbalances. Numerical results which indicate the sensitivity of the carrier tracking loop and the telemetry symbol-error rate (SER) to various parameters of the models are also provided as a tool in the design of the subcarrier balanced modulator.

  14. An unbalanced spectra classification method based on entropy

    NASA Astrophysics Data System (ADS)

    Liu, Zhong-bao; Zhao, Wen-juan

    2017-05-01

    How to solve the problem of distinguishing the minority spectra from the majority of the spectra is quite important in astronomy. In view of this, an unbalanced spectra classification method based on entropy (USCM) is proposed in this paper to deal with the unbalanced spectra classification problem. USCM greatly improves the performances of the traditional classifiers on distinguishing the minority spectra as it takes the data distribution into consideration in the process of classification. However, its time complexity is exponential with the training size, and therefore, it can only deal with the problem of small- and medium-scale classification. How to solve the large-scale classification problem is quite important to USCM. It can be easily obtained by mathematical computation that the dual form of USCM is equivalent to the minimum enclosing ball (MEB), and core vector machine (CVM) is introduced, USCM based on CVM is proposed to deal with the large-scale classification problem. Several comparative experiments on the 4 subclasses of K-type spectra, 3 subclasses of F-type spectra and 3 subclasses of G-type spectra from Sloan Digital Sky Survey (SDSS) verify USCM and USCM based on CVM perform better than kNN (k nearest neighbor) and SVM (support vector machine) in dealing with the problem of rare spectra mining respectively on the small- and medium-scale datasets and the large-scale datasets.

  15. Neighborhood functions alter unbalanced facilitation on a stress gradient.

    PubMed

    Malanson, George P; Resler, Lynn M

    2015-01-21

    The stress-gradient hypothesis states that individual and species competitive and facilitative effects change in relative importance or intensity along environmental gradients of stress. The importance of the number of facilitators in the neighborhood of a potential beneficiary has not been explored. Evenly distributed and stress-correlated facilitation and the increase in the intensity of facilitation with neighbors as linear, logarithmic, and unimodal functions is simulated for two hypothetical species, both of which improve the local environment. The mutualism is unbalanced in that the establishment of one species is enhanced by neighbors more than the other. Compared to no facilitation or evenly distributed facilitation, the stress gradient produces more edges in the spatially advancing population, more overall intensity of facilitation, and more individuals further advanced into the area of higher stress; the more enhanced species has increased population relative to the other - to the point where they are equal. Among three neighborhood functions, little difference exists in outcomes between the linear and logarithmic functions, but the unimodal function, which shifts peak facilitation intensity to fewer neighbors, increases the above state variables more than the differences between the even and stress gradient facilitation scenarios; the population of the beneficiary species exceeds that of the other. Different neighborhood functions change the effects of spatial pattern on the biological outcome. The unbalanced mutualism may be important where additional species alter the basic interaction in the high stress area of the environmental gradient, such as ecotones where the spatial pattern becomes central to facilitation.

  16. Leaf Length Tracker: a novel approach to analyse leaf elongation close to the thermal limit of growth in the field.

    PubMed

    Nagelmüller, Sebastian; Kirchgessner, Norbert; Yates, Steven; Hiltpold, Maya; Walter, Achim

    2016-03-01

    Leaf growth in monocot crops such as wheat and barley largely follows the daily temperature course, particularly under cold but humid springtime field conditions. Knowledge of the temperature response of leaf extension, particularly variations close to the thermal limit of growth, helps define physiological growth constraints and breeding-related genotypic differences among cultivars. Here, we present a novel method, called 'Leaf Length Tracker' (LLT), suitable for measuring leaf elongation rates (LERs) of cereals and other grasses with high precision and high temporal resolution under field conditions. The method is based on image sequence analysis, using a marker tracking approach to calculate LERs. We applied the LLT to several varieties of winter wheat (Triticum aestivum), summer barley (Hordeum vulgare), and ryegrass (Lolium perenne), grown in the field and in growth cabinets under controlled conditions. LLT is easy to use and we demonstrate its reliability and precision under changing weather conditions that include temperature, wind, and rain. We found that leaf growth stopped at a base temperature of 0°C for all studied species and we detected significant genotype-specific differences in LER with rising temperature. The data obtained were statistically robust and were reproducible in the tested environments. Using LLT, we were able to detect subtle differences (sub-millimeter) in leaf growth patterns. This method will allow the collection of leaf growth data in a wide range of future field experiments on different graminoid species or varieties under varying environmental or treatment conditions.

  17. Leaf Length Tracker: a novel approach to analyse leaf elongation close to the thermal limit of growth in the field

    PubMed Central

    Kirchgessner, Norbert; Yates, Steven; Hiltpold, Maya; Walter, Achim

    2016-01-01

    Leaf growth in monocot crops such as wheat and barley largely follows the daily temperature course, particularly under cold but humid springtime field conditions. Knowledge of the temperature response of leaf extension, particularly variations close to the thermal limit of growth, helps define physiological growth constraints and breeding-related genotypic differences among cultivars. Here, we present a novel method, called ‘Leaf Length Tracker’ (LLT), suitable for measuring leaf elongation rates (LERs) of cereals and other grasses with high precision and high temporal resolution under field conditions. The method is based on image sequence analysis, using a marker tracking approach to calculate LERs. We applied the LLT to several varieties of winter wheat (Triticum aestivum), summer barley (Hordeum vulgare), and ryegrass (Lolium perenne), grown in the field and in growth cabinets under controlled conditions. LLT is easy to use and we demonstrate its reliability and precision under changing weather conditions that include temperature, wind, and rain. We found that leaf growth stopped at a base temperature of 0°C for all studied species and we detected significant genotype-specific differences in LER with rising temperature. The data obtained were statistically robust and were reproducible in the tested environments. Using LLT, we were able to detect subtle differences (sub-millimeter) in leaf growth patterns. This method will allow the collection of leaf growth data in a wide range of future field experiments on different graminoid species or varieties under varying environmental or treatment conditions. PMID:26818912

  18. Monte Carlo simulations of the electric field close to the body in realistic environments for application in personal radiofrequency dosimetry.

    PubMed

    Iskra, S; McKenzie, R; Cosic, I

    2011-11-01

    Personal dosemeters can play an important role in epidemiological studies and in radiofrequency safety programmes. In this study, a Monte Carlo approach is used in conjunction with the finite difference time domain method to obtain distributions of the electric field strength close to a human body model in simulated realistic environments. The field is a proxy for the response of an ideal body-worn electric field dosemeter. A set of eight environments were modelled based on the statistics of Rayleigh, Rice and log-normal fading to simulate outdoor and indoor multipath exposures at 450, 900 and 2100 MHz. Results indicate that a dosemeter mounted randomly within 10-50 mm of the adult or child body model (torso region) will on average underestimate the spatially averaged value of the incident electric field strength by a factor of 0.52 to 0.74 over the frequencies of 450, 900 and 2100 MHz. The uncertainty in results, assessed at the 95 % confidence level (between the 2.5th and 97.5th percentiles) was largest at 2100 MHz and smallest at 450 MHz.

  19. Enhanced electro-magnetic energy transfer between a hot and cold body at close spacing due to evanescent fields

    SciTech Connect

    Raynolds, J.E.

    1998-10-01

    Theoretical studies have demonstrated that the energy transfer between a hot and cold body at close spacing (on the order of the radiation wavelength) can greatly exceed the limit for black body radiation (ie, Power = {sigma}T{sup 4}). This effect, due to the coupling of evanescent fields, presents an attractive option for thermo-photovoltaic (TPV) applications (assuming the considerable technical challenges can be overcome). The magnitude of the enhanced energy transfer depends on the optical properties of the hot and cold bodies as characterized by the dielectric functions of the respective materials. The present study considers five different situations as specified by the materials choices for the hot/cold sides: metal/metal, metal/insulator, metal/semiconductor, insulator/insulator, and semiconductor/semiconductor. For each situation, the dielectric functions are specified by typical models. An increase in energy transfer (relative to the black body law) is found for all situations considered, for separations less than one micron, assuming a temperature difference of 1,000 C. The metal/metal situation has the highest increase vs. separation while the semiconductor/semiconductor has the lowest. Factor-of-ten increases are obtained at roughly 0.1 microns for the metal/metal and roughly 0.02 microns for the metal/semiconductor. These studies are helping to increase the understanding of the close-spaced effect in the context of a radiator/TPV context.

  20. Transient analysis of unbalanced short circuits of the ERDA-NASA 100 kW wind turbine alternator

    NASA Technical Reports Server (NTRS)

    Hwang, H. H.; Gilbert, L. J.

    1976-01-01

    Unbalanced short-circuit faults on the alternator of the ERDA-NASA Mod-O100-kW experimental wind turbine are studied. For each case, complete solutions for armature, field, and damper-circuit currents; short-circuit torque; and open-phase voltage are derived directly by a mathematical analysis. Formulated results are tabulated. For the Mod-O wind turbine alternator, numerical calculations are given, and results are presented by graphs. Comparisons for significant points among the more important cases are summarized. For these cases the transients are found to be potentially severe. The effect of the alternator neutral-to-ground impedance is evaluated.

  1. QST-FST comparisons with unbalanced half-sib designs.

    PubMed

    Gilbert, Kimberly J; Whitlock, Michael C

    2015-03-01

    QST , a measure of quantitative genetic differentiation among populations, is an index that can suggest local adaptation if QST for a trait is sufficiently larger than the mean FST of neutral genetic markers. A previous method by Whitlock and Guillaume derived a simulation resampling approach to statistically test for a difference between QST and FST , but that method is limited to balanced data sets with offspring related as half-sibs through shared fathers. We extend this approach (i) to allow for a model more suitable for some plant populations or breeding designs in which offspring are related through mothers (assuming independent fathers for each offspring; half-sibs by dam); and (ii) by explicitly allowing for unbalanced data sets. The resulting approach is made available through the R package QstFstComp.

  2. Analysis of distorted unbalanced waveforms in inverter drives

    NASA Astrophysics Data System (ADS)

    Andria, Gregorio; dell'Aquila, Antonio; Salvatore, Luigi

    1989-04-01

    A technique for determining the degree of unbalance in a three-phase electrical system is developed and demonstrated. Expressions for the distorted and unbalanced waveforms are derived; the effects of such waveforms on the performance of induction motors are estimated; the analysis of a typical system is outlined; and the errors inherent in FFT harmonic analysis are evaluated. A PC-based experimental digital measurement system is implemented, tested, and applied to a commercial three-phase PWM inverter with continuous output power 11 kVA, output voltage 380 V, and output frequency 5-50 Hz. The results are presented in extensive tables and graphs and characterized in detail, demonstrating the effectiveness of the procedure.

  3. Research on three-phase unbalanced distribution network reconfiguration strategy

    NASA Astrophysics Data System (ADS)

    Hu, Shuang; Li, Ke-Jun; Xu, Yanshun; Liu, Zhijie; Guo, Jing; Wang, Zhuodi

    2017-01-01

    With the development of social economy, the loads installed in the distribution network become more and more complex which may cause the three-phase unbalance problems. This paper proposes an optimal reconfiguration approach based on mixed integer quadric programming (MIQP) method to address the three-phase unbalance problem. It aims to minimize the total network losses of the system. By using several square constraints to substitute the circular constraint, the original optimization problem is linearized and converted into a mixed-integer linear programming (MILP) model. Then this MILP problem is solved in general algebraic model system (GAMS) software using CPLEX solver. The additional losses caused by three-phase unbalanced are also considered. An IEEE 34 nodes test system is used to demonstrate the feasibility and effectiveness of the proposed method. The results show that the losses and the voltage violation mitigation in the network can be reduced significantly.

  4. Large unbalanced credit scoring using Lasso-logistic regression ensemble.

    PubMed

    Wang, Hong; Xu, Qingsong; Zhou, Lifeng

    2015-01-01

    Recently, various ensemble learning methods with different base classifiers have been proposed for credit scoring problems. However, for various reasons, there has been little research using logistic regression as the base classifier. In this paper, given large unbalanced data, we consider the plausibility of ensemble learning using regularized logistic regression as the base classifier to deal with credit scoring problems. In this research, the data is first balanced and diversified by clustering and bagging algorithms. Then we apply a Lasso-logistic regression learning ensemble to evaluate the credit risks. We show that the proposed algorithm outperforms popular credit scoring models such as decision tree, Lasso-logistic regression and random forests in terms of AUC and F-measure. We also provide two importance measures for the proposed model to identify important variables in the data.

  5. Large Unbalanced Credit Scoring Using Lasso-Logistic Regression Ensemble

    PubMed Central

    Wang, Hong; Xu, Qingsong; Zhou, Lifeng

    2015-01-01

    Recently, various ensemble learning methods with different base classifiers have been proposed for credit scoring problems. However, for various reasons, there has been little research using logistic regression as the base classifier. In this paper, given large unbalanced data, we consider the plausibility of ensemble learning using regularized logistic regression as the base classifier to deal with credit scoring problems. In this research, the data is first balanced and diversified by clustering and bagging algorithms. Then we apply a Lasso-logistic regression learning ensemble to evaluate the credit risks. We show that the proposed algorithm outperforms popular credit scoring models such as decision tree, Lasso-logistic regression and random forests in terms of AUC and F-measure. We also provide two importance measures for the proposed model to identify important variables in the data. PMID:25706988

  6. Active Vibration Isolation of an Unbalanced Machine Spindle

    SciTech Connect

    Hopkins, D J; Geraghty, P

    2004-08-13

    Proper configurations of controls, sensors, and metrology technologies have enabled precision turning machines to achieve nanometer positioning. However, at this level of positioning resolution, vibration sources can become a limiting factor. One of the largest sources of vibration in a turning machine may be an unbalanced rotating spindle. In this paper, a system is implemented to actively cancel spindle unbalance forces. Specifically, to attenuate the spindle housing vibration using an active vibration control system to prevent the unbalance force from disturbing the rest of the machine systems e.g., the slide servo system or the machine metrology frame. The system controls three degrees of motion. An unbalanced spindle creates a rotating force vector with a once per revolution period. The cause and size of this force is a function of the spindle, the part, the part fixturing, the part setup and the spindle speed. In addition, certain spindle speeds coupled with the size of the unbalance force may contain other harmonics that can excite machine structural resonances. The magnitude of the unbalance force increases as the square of the spindle speed. The control algorithm of this system is fully implemented on a commercially available machine tool controller and is sensitive only to unbalance induced motion. The paper describes in detail the control algorithm and how it is implemented. The system has demonstrated the ability to adapt in real time to remove the fundamental component of the unbalance force to nanometer levels. However, higher-order structural resonance components of the test bed have been observed when the system is active. The control system is stable and the voice coil (VC) excitation is harmonically clean but the high Q of the mechanical test system is apparently excited by energy leakage. Our results indicate the need to carefully examine the dynamics of any spindle system that would take advantage of this active system.

  7. Ensemble Pruning for Glaucoma Detection in an Unbalanced Data Set.

    PubMed

    Adler, Werner; Gefeller, Olaf; Gul, Asma; Horn, Folkert K; Khan, Zardad; Lausen, Berthold

    2016-12-07

    Random forests are successful classifier ensemble methods consisting of typically 100 to 1000 classification trees. Ensemble pruning techniques reduce the computational cost, especially the memory demand, of random forests by reducing the number of trees without relevant loss of performance or even with increased performance of the sub-ensemble. The application to the problem of an early detection of glaucoma, a severe eye disease with low prevalence, based on topographical measurements of the eye background faces specific challenges. We examine the performance of ensemble pruning strategies for glaucoma detection in an unbalanced data situation. The data set consists of 102 topographical features of the eye background of 254 healthy controls and 55 glaucoma patients. We compare the area under the receiver operating characteristic curve (AUC), and the Brier score on the total data set, in the majority class, and in the minority class of pruned random forest ensembles obtained with strategies based on the prediction accuracy of greedily grown sub-ensembles, the uncertainty weighted accuracy, and the similarity between single trees. To validate the findings and to examine the influence of the prevalence of glaucoma in the data set, we additionally perform a simulation study with lower prevalences of glaucoma. In glaucoma classification all three pruning strategies lead to improved AUC and smaller Brier scores on the total data set with sub-ensembles as small as 30 to 80 trees compared to the classification results obtained with the full ensemble consisting of 1000 trees. In the simulation study, we were able to show that the prevalence of glaucoma is a critical factor and lower prevalence decreases the performance of our pruning strategies. The memory demand for glaucoma classification in an unbalanced data situation based on random forests could effectively be reduced by the application of pruning strategies without loss of performance in a population with increased

  8. Closed-loop, non-linear feedback control simulations of beam-driven field-reversed configurations (FRCs)

    NASA Astrophysics Data System (ADS)

    Rath, N.; Onofri, M.; Barnes, D.; Romero, J.; the TAE Team

    2015-11-01

    The C-2U device has recently demonstrated sustainment of an advanced, beam-driven FRC over time scales longer than the characteristic times for confinement, fast ion slow-down, and wall current decay. In anticipation of further advances in plasma lifetime, we are developing feedback control techniques for major FRC parameters and resistive instabilities. The LamyRidge code solves the time-dependent extended MHD equations in axisymmetric geometry. In the Q2D code, LamyRidge is combined with a 3-D kinetic code that tracks fast ions and runs in parallel with LamyRidge. Periodically, the background fields in the kinetic code are updated from the MHD simulation and the averaged fast particle distribution is integrated into the fluid equations. Recently, we have added the capability to run Q2D simulations as subordinate processes in Simulink, giving us the ability to run non-linear, closed-loop simulations using control algorithms developed in Simulink. The same Simulink models can be exported to real-time targets (CPU or FPGA) to perform feedback control in experiments. We present closed-loop simulations of beam-driven FRCs under magnetically-actuated feedback control. Results for positionally unstable FRCs are compared with the predictions of a linearized rigid-plasma model. Plasmas predicted to be passively stabilized by the linear model are found to exhibit Alfvenic growth in several cases. Feedback gains predicted to be stabilizing in the linear model are generally found to be insufficient in non-linear simulations, and vice versa. Control of separatrix geometry is demonstrated.

  9. Nuclear volume differences between balanced and unbalanced spermatozoa in chromosomal translocation carriers.

    PubMed

    Rouen, Alexandre; Lavillaureix, Alinoë; Hyon, Capucine; Heide, Solveig; Clède, Sylvain; Balet, Richard; Kott, Esther; Cassuto, Nino Guy; Siffroi, Jean-Pierre

    2015-03-01

    While chromosomal translocations are usually associated with a normal phenotype, they can still cause male infertility as well as recurrent miscarriages and fetal malformations related to their transmission in an unbalanced state. The distinction between balanced and unbalanced spermatozoa on morphological criteria is still unfeasible. However, we previously showed that: i) spermatozoa with an unbalanced content have a higher rate of DNA fragmentation; and ii) that density gradient centrifugation partially separates balanced from unbalanced sperm cells. We hypothesized that a chromosomal imbalance could alter the fine spermatic nuclear architecture and consequently the condensation of DNA, thus modifying normal sperm density. Spermatic nuclear volumes in four translocation carriers were analyzed using confocal microscopy. Secondarily, FISH analysis was used to establish the segregation mode of each spermatozoon. We found the average spermatic nuclei size to be higher among unbalanced spermatozoa in all patients but one. All the unbalanced modes were associated with larger nuclei in two patients, while this was the case for the 3:1 mode only in the other two, suggesting an abnormal condensation. This could be the first step in elaborating a procedure to completely eliminate unbalanced spermatozoa from semen prior to in vitro fertilization. Copyright © 2014 Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.

  10. A closed-form solution of wake-fields in an elliptical pill-box by using an elliptical coordinate system

    NASA Astrophysics Data System (ADS)

    Yang, J. S.; Chen, K. W.

    1989-10-01

    It was known from a complete model analysis1,2 that the wake potential in the pill-box cavity is predominantly determined by a few longitudinal modes counting from the fundamental longitudinal mode. An approach to find the longitudinal modes of an elliptical cavity is developed by means of the coordinate transformation method. It is found that the field configuration and eigenfrequencies of the elliptical cavity can be expressed in a closed form in terms of Mathieu functions. Inserting the closed form solution of modes into the previous analytical formula for the wake field, the wake field is expressed too in a closed form solution, which is convenient for numerical calculation. Thus, a numerical method to calculate expediently the wake field is developed, and a model calculation is presented.

  11. Signatures of the nightside open closed magnetic field-line boundary during moderately disturbed conditions and ionospheric substorms

    NASA Astrophysics Data System (ADS)

    Parkinson, M. L.; Pinnock, M.; Dyson, P. L.; Devlin, J. C.

    The comparatively low latitude of the Tasman International Geospace Environment Radar (TIGER) (147.2°E, 43.4°S, geographic; -54.6°Λ), a Southern Hemisphere HF SuperDARN radar, facilitates the observation of extensive backscatter from decametre-scale irregularities drifting in the auroral and polar cap ionosphere in the midnight sector. The radar often detects a persistent, sharp increase over ˜90 km of range in line-of-sight Doppler velocity spread, or spectral width, from <50 m s -1 at lower latitude to >200 m s -1 at higher latitude. It was previously shown that for moderately disturbed conditions in the pre-midnight sector, the location of the spectral width boundary (SWB) corresponds to the poleward edge of the auroral oval, as determined from energy spectra of precipitating particles measured on board Defense Meteorology Satellite Program satellites. This implies the radar SWB is a proxy for the open-closed magnetic field-line boundary (OCB) under these particular conditions. Here we investigate whether the radar SWB is aligned with the satellite OCB under a broader range of geomagnetic conditions including small to moderate substorms occurring in the pre- and post-magnetic midnight sectors. The behaviour of the SWB can be reconciled with the spatial and temporal variations of energetic particle precipitation throughout the substorm cycle.

  12. A New Linearization Method of Unbalanced Electrical Distribution Networks

    SciTech Connect

    Liu, Guodong; Xu, Yan; Ceylan, Oguzhan; Tomsovic, Kevin

    2014-01-01

    Abstract--- With increasing penetration of distributed generation in the distribution networks (DN), the secure and optimal operation of DN has become an important concern. As DN control and operation strategies are mostly based on the linearized sensitivity coefficients between controlled variables (e.g., node voltages, line currents, power loss) and control variables (e.g., power injections, transformer tap positions), efficient and precise calculation of these sensitivity coefficients, i.e. linearization of DN, is of fundamental importance. In this paper, the derivation of the node voltages and power loss as functions of the nodal power injections and transformers' tap-changers positions is presented, and then solved by a Gauss-Seidel method. Compared to other approaches presented in the literature, the proposed method takes into account different load characteristics (e.g., constant PQ, constant impedance, constant current and any combination of above) of a generic multi-phase unbalanced DN and improves the accuracy of linearization. Numerical simulations on both IEEE 13 and 34 nodes test feeders show the efficiency and accuracy of the proposed method.

  13. Sustaining high performance: dynamic balancing in an otherwise unbalanced system.

    PubMed

    Wolf, Jason A

    2011-01-01

    As Ovid said, "There is nothing in the whole world which is permanent." It is this very premise that frames the discoveries in this chapter and the compelling paradox it has raised. What began as a question of how performance is sustained, unveiled a collection of core organizational paradoxes. The findings ultimately suggest that sustained high performance is not a permanent state an organization achieves, but rather it is through perpetual movement and dynamic balance that sustainability occurs. The idea of sustainability as movement is predicated on the ability of organizational members to move beyond the experience of paradox as an impediment to progress. Through holding three critical "movements"--agile/consistency, collective/individualism, and informative/inquiry--not as paradoxical, but as active polarities, the organizations in the study were able to transcend paradox, and take active steps to continuous achievement in outperforming their peers. The study, focused on a collection of hospitals across the Unites States, reveals powerful stories of care and service, of the profound grace of human capacity, and of clear actions taken to create significant results. All of this was achieved in an environment of great volatility, in essence an unbalanced system. It was the discovery of movement and ultimately of dynamic balancing that allowed the organizations to in this study to move beyond stasis to the continuous "state" of sustaining high performance.

  14. Overdose Intake of Curcumin Initiates the Unbalanced State of Bodies.

    PubMed

    Qiu, Peiyu; Man, Shuli; Li, Jing; Liu, Jing; Zhang, Liming; Yu, Peng; Gao, Wenyuan

    2016-04-06

    Curcumin is the major active component of turmeric and widely used as a spice and coloring agent in food. However, its safety evaluation has been little investigated. To evaluate the 90-day subchronic toxicity of curcumin in rats, its general observation, clinical biochemistry, pathology, and metabolomics were evaluated. The results showed that curcumin induced liver injury through the generation of the overexpression of reactive oxygen species (ROS) and pro-inflammatory cytokines IL-6 and the decreases of the levels of antioxidant enzyme SOD and detoxified enzyme GST. Meanwhile, for the self-protection of rats, curcumin treatment activated the transcription of Nrf-2 and elevated the expression of HO-1 to reduce tissue damage. Furthermore, curcumin significantly increased key mRNA levels of HK2, PKM2, LDHA, CES, Cpt1, Cpt2, FASN, and ATP5b and decreased levels of GLUT2 and ACC1 to enhance glycolysis and inhibit lipid metabolism and TCA cycle. Therefore, overdose or long-term intake of curcumin could initiate the unbalanced state of bodies through oxidative stress, inflammation, and metabolic disorders, which induces liver injury. Intermittent administration of curcumin is necessary in our daily lives.

  15. A balanced perspective on unbalanced growth and thymineless death

    PubMed Central

    Hanawalt, Philip C.

    2015-01-01

    The early history of the esoteric phenomenon of thymineless death (TLD) is recounted, from the pioneering discovery by Seymour Cohen and Hazel Barner, through my graduate studies at Yale and postdoctoral research in Copenhagen. My principal contribution was the discovery that restricted synthesis of protein and RNA permits cultures of Escherichia coli to complete their DNA replication cycles without initiating new ones, and that cells held in this physiological state are immune to the lethality of thymine deprivation; unbalanced growth is not the fundamental cause of TLD. The successful synchronization of the DNA replication cycle contributed to formulation of the replicon concept. Studies at Stanford revealed a specific requirement for transcription and led to the discovery of a TLD-resistant mutant in a new gene, termed recQ, with important homologs in humans and most other organisms. The lessons learned from research on TLD underscore the value of basic research in bacterial systems that can have profound implications for human health. PMID:26097468

  16. Use of unbalanced laminates as a screening method for microcracking

    NASA Technical Reports Server (NTRS)

    Papadopoulos, Demetrios S.; Bowles, Kenneth J.

    1990-01-01

    State-of-the-art, high temperature polyimide matrix composites, reinforced with continuous graphite fibers are known to be susceptible to intraply cracking when thermally cycled over their useful service temperature range. It is believed that the transply cracking, in part, results from residual stresses caused by differences in coefficients of thermal expansion (CTE) between the polymer matrix and the reinforcement. Thermal cycling tests to investigate this phenomenon involve expensive time and energy consuming programs which are not economically feasible for use as a part of a materials screening process. As an alternative to thermal cycling studies, a study of unbalanced crossply graphite fiber reinforcement composites was conducted to assess the effect of the composite ply layup and surface condition on the residual stresses that remain after the processing of these materials. The residual stresses were assessed by measuring the radii of curvature of the types of laminates that were studied. The temperature at which stress-free conditions existed were determined and a dye penetrant method was used to observe surface damage resulting from excessive residual stress buildup. These results are compared with some published results of thermal cycling tests that were previously conducted on balanced polyimide composites.

  17. Unbalanced quantized multiple description video transmission using path diversity

    NASA Astrophysics Data System (ADS)

    Ekmekci, Sila; Sikora, Thomas

    2003-05-01

    Multiple Description Coding is a forward error correction scheme where two or more descriptions of the source are sent to the receiver over different channels. If only one channel is received the signal can be reconstructed with distortion D1 or D2. On the other hand, if both channels rae received the combined information is used to achieve a lower distortion D0. Our approach is based on the Multiple State Video Coding with the novelty that we achieve a flexible unbalance rate of the two streams by varying the quantization step size while keeping the original frame rate constant. The total bitrate Rτ is fixed which is to be allocated between the two streams. If the assigned bitratres are not balanced there will be PSNR variations between neighboring frames after reconstruction. Our goal is to find the optimal rate allocation while maximizing the average reconstructed frame PSNR and minimizing the PSNR variations given the total bitrate Rτ and the packet loss probabilities p1 and p2 over the two paths. The reconstruction algorithm is also taken into account in the optimization process. The paper will report results presenting optimal system designs for balanced but also for unbalanced path conditions.

  18. Prenatal diagnosis of two different unbalanced forms of an inherited (Y;12) translocation.

    PubMed

    Mademont-Soler, Irene; Morales, Carme; Madrigal, Irene; Margarit, Ester; Bruguera, Jordi; Clusellas, Núria; Martínez, José M; Borrell, Antoni; Sánchez, Aurora; Soler, Anna

    2009-12-01

    The identification of an unexpected structural chromosome rearrangement at prenatal diagnosis can be problematic and raises unique genetic counseling issues. We describe two consecutive prenatal cases within a family with an inherited unbalanced (Y;12) translocation and discuss the genotype-phenotype correlation. The first fetus presented with 12qter monosomy and pseudoautosomal region 2 trisomy, while the second fetus had the alternative unbalanced state. Although the first fetus had a structural heart defect, such small imbalances might not give sonographic findings, making their prenatal diagnosis difficult. However, congenital abnormalities are expected in both unbalanced forms of the translocation, including mental retardation, which could be explained by the gene dosage variation of P2RX2. To our knowledge, these are the first published cases reporting this subtype of (Y;12) translocation, in both balanced and unbalanced states.

  19. Mosaicism for trisomy 3q arising from an unbalanced, de novo t(3;15).

    PubMed Central

    Stallings, R; Vaughn, D; Hall, K; Joyce, C; Ryan, F; Barton, D; Geraghty, M

    1997-01-01

    We report on a 2 1/2 year old girl who is dysmorphic, developmentally delayed, and mosaic for an unbalanced, de novo translocation between chromosomes 3 and 15. The karyotype from peripheral blood lymphocytes is 46,XX (50) and the karyotype from skin fibroblasts is 46,XX (28)/46,XX,der(15)t(3;15)(q11;p11) (23). The mechanism for the generation of this unbalanced, de novo translocation is discussed. Images PMID:9192276

  20. A global wave-driven magnetohydrodynamic solar model with a unified treatment of open and closed magnetic field topologies

    SciTech Connect

    Oran, R.; Van der Holst, B.; Landi, E.; Jin, M.; Sokolov, I. V.; Gombosi, T. I.

    2013-12-01

    We describe, analyze, and validate the recently developed Alfvén Wave Solar Model, a three-dimensional global model starting from the top of the chromosphere and extending into interplanetary space (out to 1-2 AU). This model solves the extended, two-temperature magnetohydrodynamics equations coupled to a wave kinetic equation for low-frequency Alfvén waves. In this picture, heating and acceleration of the plasma are due to wave dissipation and to wave pressure gradients, respectively. The dissipation process is described by a fully developed turbulent cascade of counterpropagating waves. We adopt a unified approach for calculating the wave dissipation in both open and closed magnetic field lines, allowing for a self-consistent treatment in any magnetic topology. Wave dissipation is the only heating mechanism assumed in the model; no geometric heating functions are invoked. Electron heat conduction and radiative cooling are also included. We demonstrate that the large-scale, steady state (in the corotating frame) properties of the solar environment are reproduced, using three adjustable parameters: the Poynting flux of chromospheric Alfvén waves, the perpendicular correlation length of the turbulence, and a pseudoreflection coefficient. We compare model results for Carrington rotation 2063 (2007 November-December) with remote observations in the extreme-ultraviolet and X-ray ranges from the Solar Terrestrial Relations Observatory, Solar and Heliospheric Observatory, and Hinode spacecraft and with in situ measurements by Ulysses. The results are in good agreement with observations. This is the first global simulation that is simultaneously consistent with observations of both the thermal structure of the lower corona and the wind structure beyond Earth's orbit.

  1. Patterns of transcriptome divergence in the male accessory gland of two closely related species of field crickets.

    PubMed

    Andrés, Jose A; Larson, Erica L; Bogdanowicz, Steven M; Harrison, Richard G

    2013-02-01

    One of the central questions in evolutionary genetics is how much of the genome is involved in the early stages of divergence between populations, causing them to be reproductively isolated. In this article, we investigate genomic differentiation in a pair of closely related field crickets (Gryllus firmus and G. pennsylvanicus). These two species are the result of allopatric divergence and now interact along an extensive hybrid zone in eastern North America. Genes encoding seminal fluid proteins (SFPs) are often divergent between species, and it has been hypothesized that these proteins may play a key role in the origin and maintenance of reproductive isolation between diverging lineages. Hence, we chose to scan the accessory gland transcriptome to enable direct comparisons of differentiation for genes known to encode SFPs with differentiation in a much larger set of genes expressed in the same tissue. We have characterized differences in allele frequency between two populations for >6000 SNPs and >26,000 contigs. About 10% of all SNPs showed nearly fixed differences between the two species. Genes encoding SFPs did not have significantly elevated numbers of fixed SNPs per contig, nor did they seem to show larger differences than expected in their average allele frequencies. The distribution of allele frequency differences across the transcriptome is distinctly bimodal, but the relatively high proportion of fixed SNPs does not necessarily imply "ancient" divergence between these two lineages. Further studies of linkage disequilibrium and introgression across the hybrid zone are needed to direct our attention to those genome regions that are important for reproductive isolation.

  2. Variations in sour gas concentrations in the NSB [open quote]A[close quote] field, offshore north Sumatra

    SciTech Connect

    Reaves, C.M. )

    1996-01-01

    Sour gas concentrations in DST samples from the NSB [open quote]A[close quote] field show wide variations. This can be observed in tests from different wells, different tests from the same well and different samples from the same test. H[sub 2]S measurements show the most obvious variations, from less than 0.5% to greater than 5%. CO[sub 2] measurements also vary beyond normal sampling or analytical errors. Geological considerations suggest that these variations are not controlled by subsurface reservoir properties. DST rate and volume data suggest that variations in sour gas concentrations are controlled by the production of formation water. Minimum sour gas concentrations occur in DST samples with water production rates which match those predicted for water vapor condensation. Elevated SW gas concentrations occur in DST's in which produced water either exceeds or falls short of water vapor condensation predictions. In the case of excess water production, the source of the elevated sour gas concentrations is clear. Formation water in equilibrium with a gas phase containing the minimum sour gas concentration, 28% CO[sub 2] and 0.5% HA would contain a dissolved gas with 80% CO[sub 2] and 10% H[sub 2]S. Exsolution of this dissolved gas during DST operations would result in substantial increases in sour gas concentrations. In tests with water deficits, it is probable that liquids are being trapped in the subsurface, but this cannot be proved. These observations have been extended to a database on sour gas concentrations in north Sumatra and have had a substantial impact on assessments of the exploration and resource potential of this area.

  3. Pointing and Scanning Control of Instruments Using Rotating Unbalanced Masses

    NASA Technical Reports Server (NTRS)

    Hung, John Y.

    1996-01-01

    Motions of telescopes, satellites, and other flight bodies have been controlled by various means in the past. For example, gimbal mounted devices can use electric motors to produce pointing and scanning motions. Reaction wheels, control moment gyros, and propellant-charged reaction jets are other technologies that have also been used. Each of these methods has its advantages, but all actuator systems used in a flight environment face the challenges of minimizing weight, reducing energy consumption, and maximizing reliability. Recently, Polites invented and patented the Rotating Unbalanced Mass (RUM) device as a means for generation scanning motion on flight experiments. RUM devices have been successfully used to generate various scanning motions. The basic principle: a RUM rotating at constant annular velocity exerts a cyclic centrifugal force on the instrument or main body, thus producing a periodic scanning motion. A system of RUM devices exerts no reaction forces on the main body, requires very little energy, and is very simple to construct and control. These are significant advantages over electric motors, reaction wheels, and control moment gyroscopes. Although the RUM device very easily produces scanning motion, an auxiliary control system may be required to maintain the proper orientation, or pointing of the main body. It has been suggested that RUM devices can be used to control pointing dynamics, as well as generate the desired periodic scanning motion. The idea is that the RUM velocity will not be constant, but will vary over the period of one RUM rotation. The thought is that the changing angular velocity produces a centrifugal force having time-varying magnitude and direction. The scope of the present research project is to further study the pointing control concept, and to implement a microcontroller program to control an experimental hardware system. This report is subdivided into three themes. The basic dynamic modeling and control principles are

  4. Dynamic Models of Instruments Using Rotating Unbalanced Masses

    NASA Technical Reports Server (NTRS)

    Hung, John Y.; Gallaspy, Jason M.; Bishop, Carlee A.

    1998-01-01

    The motion of telescopes, satellites, and other flight bodies have been controlled by various means in the past. For example, gimbal mounted devices can use electric motors to produce pointing and scanning motions. Reaction wheels, control moment gyros, and propellant-charged reaction jets are other technologies that have also been used. Each of these methods has its advantages, but all actuator systems used in a flight environment face the challenges of minimizing weight, reducing energy consumption, and maximizing reliability. Recently, Polites invented and patented the Rotating Unbalanced Mass (RUM) device as a means for generation scanning motion on flight experiments. RUM devices together with traditional servomechanisms have been successfully used to generate various scanning motions: linear, raster, and circular. The basic principle can be described: A RUM rotating at constant angular velocity exerts a cyclic centrifugal force on the instrument or main body, thus producing a periodic scanning motion. A system of RUM devices exerts no reaction forces on the main body, requires very little energy to rotate the RUMS, and is simple to construct. These are significant advantages over electric motors, reaction wheels, and control moment gyroscopes. Although the RUM device very easily produces scanning motion, an auxiliary control system has been required to maintain the proper orientation, or pointing of the main body. It has been suggested that RUM devices can be used to control pointing dynamics, as well as generate the desired periodic scanning motion. The idea is that the RUM velocity will not be kept constant, but will vary over the period of one RUM rotation. The thought is that the changing angular velocity produces a centrifugal force having time-varying magnitude and direction. The scope of this ongoing research project is to study the pointing control concept, and recommend a direction of study for advanced pointing control using only RUM devices. This

  5. A mechanism for the dynamo terms to sustain closed-flux current, including helicity balance, by driving current which crosses the magnetic field

    SciTech Connect

    Jarboe, T. R.; Nelson, B. A.; Sutherland, D. A.

    2015-07-15

    An analysis of imposed dynamo current drive (IDCD) [T.R. Jarboe et al., Nucl. Fusion 52 083017 (2012)] reveals: (a) current drive on closed flux surfaces seems possible without relaxation, reconnection, or other flux-surface-breaking large events; (b) the scale size of the key physics may be smaller than is often computationally resolved; (c) helicity can be sustained across closed flux; and (d) IDCD current drive is parallel to the current which crosses the magnetic field to produce the current driving force. In addition to agreeing with spheromak data, IDCD agrees with selected tokamak data.

  6. Closing the Performance Gap in a 4th Wave and Post-Modern Society: Lessons from the Field

    ERIC Educational Resources Information Center

    Adams, J. Q.

    2005-01-01

    The USA is undergoing tremendous cultural changes as we open the first decade of the 21st century. In this paper the author discusses the need to close the performance gap that exists between White, African American, and Latino/a students. To do so, educators must carefully consider several important cultural forces. The author examines the shift…

  7. Unbalanced distribution of materials: the art of giving rise to hepatocytes from liver stem/progenitor cells.

    PubMed

    Liu, Wei-Hui; Ren, Li-Na; Chen, Tao; You, Nan; Liu, Li-Ye; Wang, Tao; Yan, Hong-Tao; Luo, Hao; Tang, Li-Jun

    2014-01-01

    Liver stem/progenitor cells (LSPCs) are able to duplicate themselves and differentiate into each type of cells in the liver, including mature hepatocytes and cholangiocytes. Understanding how to accurately control the hepatic differentiation of LSPCs is a challenge in many fields from preclinical to clinical treatments. This review summarizes the recent advances made to control the hepatic differentiation of LSPCs over the last few decades. The hepatic differentiation of LSPCs is a gradual process consisting of three main steps: initiation, progression and accomplishment. The unbalanced distribution of the affecting materials in each step results in the hepatic maturation of LSPCs. As the innovative and creative works for generating hepatocytes with full functions from LSPCs are gradually accumulated, LSPC therapies will soon be a new choice for treating liver diseases.

  8. Angular dependence of direct current decay in a closed YBCO double-pancake coil under external AC magnetic field and reduction by magnetic shielding

    NASA Astrophysics Data System (ADS)

    Geng, J.; Zhang, H.; Li, C.; Zhang, X.; Shen, B.; Coombs, T. A.

    2017-03-01

    High T c superconducting (HTS) coils are ideal candidates in the use of high field magnets. HTS coils carrying a direct current, however, suffer a non-negligible loss when they are exposed to an external AC magnetic field. Although this phenomenon is well known, no study concerning AC magnetic field angular dependence of direct current decay has ever been shown. In this work, we experimentally investigate the direct current decay characteristics in a closed double pancake coil made of a YBCO coated conductor under external AC field. AC field of different angles with respect to the coil plane is applied. Results show that the current decay rate presents a strong angular dependence. The fastest decay occurs when the field is parallel to the coil plane, in which case the surface of the tape in the outermost layer experiences most flux variation. To reduce the decay rate, we propose wrapping superconducting tapes around the outermost layer of the coil to shield external AC field. This method significantly reduces direct current decay rate under parallel field, without affecting the perpendicular self-field of the coil.

  9. Empirical Statistical Power for Testing Multilocus Genotypic Effects under Unbalanced Designs Using a Gibbs Sampler.

    PubMed

    Lee, Chaeyoung

    2012-11-01

    Epistasis that may explain a large portion of the phenotypic variation for complex economic traits of animals has been ignored in many genetic association studies. A Baysian method was introduced to draw inferences about multilocus genotypic effects based on their marginal posterior distributions by a Gibbs sampler. A simulation study was conducted to provide statistical powers under various unbalanced designs by using this method. Data were simulated by combined designs of number of loci, within genotype variance, and sample size in unbalanced designs with or without null combined genotype cells. Mean empirical statistical power was estimated for testing posterior mean estimate of combined genotype effect. A practical example for obtaining empirical statistical power estimates with a given sample size was provided under unbalanced designs. The empirical statistical powers would be useful for determining an optimal design when interactive associations of multiple loci with complex phenotypes were examined.

  10. Unbalanced and Minimal Point Equivalent Estimation Second-Order Split-Plot Designs

    NASA Technical Reports Server (NTRS)

    Parker, Peter A.; Kowalski, Scott M.; Vining, G. Geoffrey

    2007-01-01

    Restricting the randomization of hard-to-change factors in industrial experiments is often performed by employing a split-plot design structure. From an economic perspective, these designs minimize the experimental cost by reducing the number of resets of the hard-to- change factors. In this paper, unbalanced designs are considered for cases where the subplots are relatively expensive and the experimental apparatus accommodates an unequal number of runs per whole-plot. We provide construction methods for unbalanced second-order split- plot designs that possess the equivalence estimation optimality property, providing best linear unbiased estimates of the parameters; independent of the variance components. Unbalanced versions of the central composite and Box-Behnken designs are developed. For cases where the subplot cost approaches the whole-plot cost, minimal point designs are proposed and illustrated with a split-plot Notz design.

  11. Unbalanced-flow, fluid-mixing plug with metering capabilities

    NASA Technical Reports Server (NTRS)

    England, John Dwight (Inventor); Kelley, Anthony R. (Inventor); Van Buskirk, Paul D. (Inventor)

    2009-01-01

    A fluid mixer plug has holes formed therethrough such that a remaining portion is closed to fluid flow. The plug's inlet face defines a central circuit region and a ring-shaped region with the ring-shaped region including at least some of the plug's remaining portion so-closed to fluid flow. This remaining portion or closed region at each radius R of the ring shaped region satisfies a radius independent, flow-based relationship. Entry openings are defined in the plug's inlet face in correspondence with the holes. The entry openings define an open flow area at each radius of the ring-shaped region. The open flow area at each such radius satisfies the inverse of the flow-based relationship defining the closed regions of the plug.

  12. Shielding of longitudinal magnetic fields with thin, closely, spaced concentric cylindrical shells with applications to atomic clocks

    NASA Technical Reports Server (NTRS)

    Wolf, S. A.; Gubser, D. U.; Cox, J. E.

    1978-01-01

    A general formula is given for the longitudinal shielding effectiveness of N closed concentric cylinders. The use of these equations is demonstrated by application to the design of magnetic shields for hydrogen maser atomic clocks. Examples of design tradeoffs such as size, weight, and material thickness are discussed. Experimental results on three sets of shields fabricated by three manufacturers are presented. Two of the sets were designed employing the techniques described. Agreement between the experimental results and the design calculations is then demonstrated.

  13. Discontinuous gradient centrifugation (DGC) decreases the proportion of chromosomally unbalanced spermatozoa in chromosomal rearrangement carriers.

    PubMed

    Rouen, Alexandre; Balet, Richard; Dorna, Maud; Hyon, Capucine; Pollet-Villard, Xavier; Chantot-Bastaraud, Sandra; Joyé, Nicole; Portnoï, Marie-France; Cassuto, Nino Guy; Siffroi, Jean-Pierre

    2013-07-01

    Can the proportion of unbalanced spermatozoa in chromosomal rearrangement carriers be decreased through the use of discontinuous gradient centrifugation (DGC)? DGC significantly decreases the proportion of genetically unbalanced spermatozoa in chromosomal rearrangement carriers. Chromosomal rearrangement carriers present with a certain proportion of unbalanced gametes, which can lead to miscarriages or malformations in the offspring. There is presently no known way to select the balanced spermatozoa and use them for IVF. The proportion of unbalanced spermatozoa after DGC was compared with that before DGC in 21 patients with a chromosomal rearrangement. At least 500 spermatozoa were analysed per observation. Twenty-one male patients with a chromosomal rearrangement were included in this prospective study. They initially consulted for infertility, recurrent miscarriages or a history of abnormal pregnancy. The samples were split into two, with one part undergoing DGC and the other being immediately fixed. Fluorescence in situ hybridization was performed to establish the chromosome segregation pattern of each spermatozoon. DGC significantly decreased the proportion of unbalanced spermatozoa in all but 1 of the 21 chromosomal rearrangement carriers (P < 0.05). Although DGC reduces the proportion of unbalanced spermatozoa in ejaculates from patients with chromosome rearrangements this elimination is only partial and some abnormal spermatozoa remain. Means to exclude these spermatozoa to ensure that only balanced ones are used in IVF remain to be discovered. The motility and morphology of the sperm before and after DGC were not measured. Used in IVF or intrauterine insemination, DGC could decrease the chance that a man carrying a chromosomal rearrangement will father an abnormal fetus.

  14. Frequency noise suppression of a single mode laser with an unbalanced fiber interferometer for subnanometer interferometry.

    PubMed

    Šmíd, Radek; Čížek, Martin; Mikel, Břetislav; Číp, Ondřej

    2015-01-12

    We present a method of noise suppression of laser diodes by an unbalanced Michelson fiber interferometer. The unstabilized laser source is represented by compact planar waveguide external cavity laser module, ORIONTM (Redfern Integrated Optics, Inc.), working at 1540.57 nm with a 1.5-kHz linewidth. We built up the unbalanced Michelson interferometer with a 2.09 km-long arm based on the standard telecommunication single-mode fiber (SMF-28) spool to suppress the frequency noise by the servo-loop control by 20 dB to 40 dB within the Fourier frequency range, remaining the tuning range of the laser frequency.

  15. Summary report on close-coupled subsurface barrier technology: Initial field trials to full-scale demonstration

    SciTech Connect

    Heiser, J.H.; Dwyer, B.

    1997-09-01

    The primary objective of this project was to develop and demonstrate the installation and measure the performance of a close-coupled barrier for the containment of subsurface waste or contaminant migration. A close-coupled barrier is produced by first installing a conventional, low-cost, cement-grout containment barrier followed by a thin lining of a polymer grout. The resultant barrier is a cement-polymer composite that has economic benefits derived from the cement and performance benefits from the durable and resistant polymer layer. The technology has matured from a regulatory investigation of the issues concerning the use of polymers to laboratory compatibility and performance measurements of various polymer systems to a pilot-scale, single column injection at Sandia to full-scale demonstration. The feasibility of the close-coupled barrier concept was proven in a full-scale cold demonstration at Hanford, Washington and then moved to the final stage with a full-scale demonstration at an actual remediation site at Brookhaven National Laboratory (BNL). At the Hanford demonstration the composite barrier was emplaced around and beneath a 20,000 liter tank. The secondary cement layer was constructed using conventional jet grouting techniques. Drilling was completed at a 45{degree} angle to the ground, forming a cone-shaped barrier. The primary barrier was placed by panel jet-grouting with a dual-wall drill stem using a two part polymer grout. The polymer chosen was a high molecular weight acrylic. At the BNL demonstration a V-trough barrier was installed using a conventional cement grout for the secondary layer and an acrylic-gel polymer for the primary layer. Construction techniques were identical to the Hanford installation. This report summarizes the technology development from pilot- to full-scale demonstrations and presents some of the performance and quality achievements attained.

  16. Mapping the open/closed boundary in Jupiter's polar cap with a 2-D equatorial magnetic field model

    NASA Astrophysics Data System (ADS)

    Vogt, Marissa; Kivelson, Margaret; Khurana, Krishan; Walker, Raymond

    2010-05-01

    How much of Jupiter's polar cap is open to the solar wind? Where do the auroral active, dark, and swirl regions map within (or outside) the magnetosphere? With a good global magnetic field model, one could map field lines from the equator to the ionosphere and answer these and similar questions. However, such a model does not exist for Jupiter, so we have taken a different approach in mapping magnetospheric sources to auroral features. Rather than following along a model field, we map equatorial field lines to the ionosphere by requiring that the magnetic flux in some specified region at the equator equal the magnetic flux in the area to which it maps in the ionosphere (flux conservation). The equatorial flux is calculated by using a two-dimensional fit to the north-south component of the measured magnetic field at the equator. This fit accounts for changes with radial distance and local time. To estimate the internal Jovian field in the ionosphere we use a version of the VIP4 model [Connerney et al., 1998] with magnetic anomaly [Grodent et al., 2008] that has been modified to include the effects of the current sheet [Khurana, 1997]. Equating the fluxes in this way allows us to link a given position in the magnetosphere to a position in the ionosphere and to gain insight into the source of different auroral features. We will discuss the results of our mapping in the northern and southern hemispheres, particularly the locations that map to beyond the dayside magnetopause and are likely regions of open flux. We will also compare our calculations to the available auroral observations.

  17. Genotype by environment interaction and the use of unbalanced historical data for genomic selection in an international wheat breeding program

    USDA-ARS?s Scientific Manuscript database

    Genomic selection (GS) offers breeders the possibility of using historic data and unbalanced breeding trials to form training populations for predicting the performance of new lines. However, in using datasets that are unbalanced over time and space, there is increasing exposure to particular genoty...

  18. Learning from unbalanced data: a cascade-based approach for detecting clustered microcalcifications.

    PubMed

    Bria, A; Karssemeijer, N; Tortorella, F

    2014-02-01

    Finding abnormalities in diagnostic images is a difficult task even for expert radiologists because the normal tissue locations largely outnumber those with suspicious signs which may thus be missed or incorrectly interpreted. For the same reason the design of a Computer-Aided Detection (CADe) system is very complex because the large predominance of normal samples in the training data may hamper the ability of the classifier to recognize the abnormalities on the images. In this paper we present a novel approach for computer-aided detection which faces the class imbalance with a cascade of boosting classifiers where each node is trained by a learning algorithm based on ranking instead of classification error. Such approach is used to design a system (CasCADe) for the automated detection of clustered microcalcifications (μCs), which is a severely unbalanced classification problem because of the vast majority of image locations where no μC is present. The proposed approach was evaluated with a dataset of 1599 full-field digital mammograms from 560 cases and compared favorably with the Hologic R2CAD ImageChecker, one of the most widespread commercial CADe systems. In particular, at the same lesion sensitivity of R2CAD (90%) on biopsy proven malignant cases, CasCADe and R2CAD detected 0.13 and 0.21 false positives per image (FPpi), respectively (p-value=0.09), whereas at the same FPpi of R2CAD (0.21), CasCADe and R2CAD detected 93% and 90% of true lesions respectively (p-value=0.11) thus showing that CasCADe can compete with high-end CADe commercial systems.

  19. Hierarchical structures produced using unbalanced magnetron sputtering for photocatalytic degradation of Rhodamine 6G dye

    NASA Astrophysics Data System (ADS)

    Polychronopoulou, K.; Aouadi, S. M.; Sirota, B.; Stone, D. S.; Wang, L.; Kohli, P.; McCarroll, M. E.

    2014-01-01

    Novel hierarchical nanostructures of ZnO-based semiconductors were synthesized on Si using unbalanced magnetron sputtering. This fabrication method is believed to be a significant breakthrough in the field of 1D nanostructure growth on substrates. These structures were created primarily as photocatalysts to degrade pollutants in water but other applications that include solar energy harvesting are possible. The crystal structure and the morphology of these materials were evaluated using X-ray diffraction and scanning electron microscopy, respectively. The morphology of the ZnO 1D nanostructures was modified from nanowires to nanofacets to nanodots by increasing substrate bias values from -12 to -70 V. In addition, hierarchical heterostructures were created by depositing Au and ZnO onto underlying ZnO nanowires. The length of the branches (30-70 nm) was found to be controlled by the deposition time of the metal oxide, while the morphology of the resulting structure was dependent on the amount of the sputtered Au speed. Based on ellipsometry studies on representative hierarchical structures, films having thicknesses of 0.9-1.3 × 10-4 m were obtained, while their porosity reached values of 50-70 %. These heterostructures were further modified by the deposition of a TiO2 shell. The above materials were assessed in terms of their optical properties (photoluminescence spectra) and their room temperature UV-Vis photocatalytic performance in terms of degradation of Rhodamine 6G dye (model compound). The hierarchical structures of ZnO showed an enhanced photocatalytic activity (higher rate constant, k, min-1) compared to the ZnO nanorods, while the TiO2 shell had a further increase which was attributed to the enhanced surface area and to charge transfer processes at the heterojunction.

  20. Unbalanced international collaboration affects adversely the usefulness of countries' scientific output as well as their technological and social impact.

    PubMed

    Zanotto, Sonia R; Haeffner, Cristina; Guimarães, Jorge A

    2016-01-01

    The unbalanced international scientific collaboration as cause of misleading information on the country's contribution to the scientific world output was analyzed. ESI Data Base (Thomson Reuters' InCites), covering the scientific production of 217 active countries in the period 2010-2014 was used. International collaboration implicates in a high percentage (33.1 %) of double-counted world articles, thus impacting qualitative data as citations, impact and impact relative to word. The countries were divided into three groups, according to their individual contribution to the world publications: Group I (24 countries, at least 1 %) representing 83.9 % of the total double-counted world articles. Group II (40 countries, 0.1-0.99 % each). Group III, 153 countries (70.5 %) with <0.1 % and altogether 1.9 % of the world. Qualitative characteristics of each group were also analyzed: percentage of the country's GNP applied in R&D, proportion of Scientists and Engineers per million inhabitants and Human Development Index. Average international collaboration were: Group I, 43.0 %; Group II, 55.8 % and Group III, 85.2 %. We concluded that very high and unbalanced international collaboration, as presented by many countries, misrepresent the importance of their scientific production, technological and social outputs. Furthermore, it jeopardizes qualitative outputs of the countries themselves, artificially increasing their scientific impact, affecting all fields and therefore, the whole world. The data confirm that when dealing with the qualitative contribution of countries, it is necessary to take in consideration the level of international cooperation because, as seen here, it can and in fact it does create false impression of the real contribution of countries.

  1. Numerical Field Model Simulation of Full-Scale Fire Tests in a Closed Spherical/Cylindrical Vessel with Internal Ventilation

    DTIC Science & Technology

    1988-09-01

    temperature of the field is uniform and equal to the ambient temperature, which corre- sponds to a nondimensional temperature of 1.0. Pressure and density...environment at the ambient temperature. Due to the cylindrical and spherical geometry, there is a sin- gularity at a radius of zero which requires special...4.30 shows that the first isotherm, representing 15 degrees Centigrade above ambient , is only at the middle of the tank. The bottom half of the tank

  2. Giant fields of the late 80s associated with type [open quotes]A[close quotes] subduction in South America

    SciTech Connect

    Duval, B.; Cramez, C. ); Figuera, J. ); Lander, R. ); Hernandez, G. )

    1993-02-01

    About 10 billion bbl of recoverable oil have been found in these three fields for which the petroleum generating subsystem is very similar. The potential source rocks are the organic sediments associated with the major downlap surface of the post-Pangea continental encroachment sedimentary cycle, i.e., MFS 91, 5 Ma (La Luna formation). However, the concentrating physico-chemical petroleum subsystem is quite different. The El Furrial/Musipan field is associated with a Tertiary foredeep basin overlying a generating Atlantic type passive margin. On the other hand, Cusiana and Ceuta fields are associated with a Tertiary foredeep basin developed over a generating back-arc basin. The different stacking of sedimentary basins controls the migration/entrapment petroleum subsystem. In El Furrial/Musipan, decollement surfaces and their associated thrusts are predominant whereas, in Ceuta and Cusiana the majority of compressional structures are created by tectonic inversions. These tectonic settings create different petroleum systems: (a) supercharged with low impedance and lateral drainage in El Furrial/Musipan, (b) normally charged with high impedance and vertically drained in Ceuta and Cusiana area. Each case requires appropriated exploration approaches.

  3. The Status of the "Weaker" Language in Unbalanced French/German Bilingual Language Acquisition

    ERIC Educational Resources Information Center

    Bonnesen, Matthias

    2009-01-01

    In this paper, I investigate the status of the so-called "weaker" language, French, in French/German bilingual first language acquisition, using data from two children from the DuFDE-corpus (see Schlyter, 1990a), Christophe and Francois. Schlyter (1993, 1994) proposes that the "weaker" language in the unbalanced children she studied has the status…

  4. Detection of unbalanced chromosome segregations in preimplantation genetic diagnosis of translocations by short comparative genomic hibridization.

    PubMed

    Rius, Mariona; Obradors, Albert; Daina, Gemma; Ramos, Laia; Pujol, Aïda; Martínez-Passarell, Olga; Marquès, Laura; Oliver-Bonet, Maria; Benet, Jordi; Navarro, Joaquima

    2011-07-01

    To apply a comprehensive chromosomal screening through short comparative genomic hybridization (CGH) in the preimplantation genetic diagnosis (PGD) of translocations. Clinical research study. A PGD laboratory and two IVF clinics. Three Robertsonian translocation carriers, two reciprocal translocation carriers, and a double-translocation carrier. After using the short-CGH approach in the reanalysis of two unbalanced embryos, discarded from a PGD for a reciprocal translocation carrier, the same method was applied in the PGD of day-3 embryos of translocation carriers. Ability of short CGH to detect partial chromosomal abnormalities in unbalanced embryos, translocation segregation proportions, and proportion of embryos carrying chromosomal abnormalities not related to the translocations. The short-CGH technique detected errors resulting from the meiotic segregation of the chromosomes involved in the translocations and other abnormalities affecting the remaining chromosomes. Alternate segregation was detected most frequently among Robertsonian translocation cases, whereas unbalanced chromosome segregations were found predominantly in reciprocal ones. Aneuploidy and structural chromosome errors were found more frequently in Robertsonian than in reciprocal translocation carriers. Application of short-CGH PGD achieved pregnancy in two cases. Short CGH is a reliable approach for PGD of translocations, as it is capable of detecting partial chromosome errors caused by unbalanced segregations simultaneously to the screening of all chromosomes, and it may improve the results after PGD for translocation carriers. Copyright © 2011 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

  5. Performance Evaluation of Distributed Systems with Unbalanced Flows: An Analysis of the INFOPLEX Data Storage Hierarchy.

    DTIC Science & Technology

    1984-07-01

    mnd iffityl by block tmuaer) simulation, queueing network, unbalanced flows, software engineering, architectural design, data storage hierarchy...intelligent memory, data base computer A ....-- 20. AOSTRACT (Coninue an reverse side It nocooear a" Identify by block meer) A software engineering...MASSACHUSETTS INSTITUTE OF TECHNOLOGY 0 ABSTRACT * A software engineering methodology to evaluate systems performance early in the design process is

  6. Unbalanced Nature, Unbounded Bodies, and Unlimited Technology: Ecocriticism and Karen Traviss' Wess'har Series

    ERIC Educational Resources Information Center

    Sullivan, Heather I.

    2010-01-01

    While nature is often claimed to be a space of harmonized balance or an antidote to the chaos of the modern world, we need a more grounded assessment of nature as endlessly changing and much less predictable than we like to assume. In this essay, I explore Karen Traviss' provocative exploration of unbalanced nature and unbounded bodies in her…

  7. Factor analysis using mixed models of multi-environment trials with different levels of unbalancing.

    PubMed

    Nuvunga, J J; Oliveira, L A; Pamplona, A K A; Silva, C P; Lima, R R; Balestre, M

    2015-11-13

    This study aimed to analyze the robustness of mixed models for the study of genotype-environment interactions (G x E). Simulated unbalancing of real data was used to determine if the method could predict missing genotypes and select stable genotypes. Data from multi-environment trials containing 55 maize hybrids, collected during the 2005-2006 harvest season, were used in this study. Analyses were performed in two steps: the variance components were estimated by restricted maximum likelihood, using the expectation-maximization (EM) algorithm, and factor analysis (FA) was used to calculate the factor scores and relative position of each genotype in the biplot. Random unbalancing of the data was performed by removing 10, 30, and 50% of the plots; the scores were then re-estimated using the FA model. It was observed that 10, 30, and 50% unbalancing exhibited mean correlation values of 0.7, 0.6, and 0.56, respectively. Overall, the genotypes classified as stable in the biplot had smaller prediction error sum of squares (PRESS) value and prediction amplitude of ellipses. Therefore, our results revealed the applicability of the PRESS statistic to evaluate the performance of stable genotypes in the biplot. This result was confirmed by the sizes of the prediction ellipses, which were smaller for the stable genotypes. Therefore, mixed models can confidently be used to evaluate stability in plant breeding programs, even with highly unbalanced data.

  8. The Status of the "Weaker" Language in Unbalanced French/German Bilingual Language Acquisition

    ERIC Educational Resources Information Center

    Bonnesen, Matthias

    2009-01-01

    In this paper, I investigate the status of the so-called "weaker" language, French, in French/German bilingual first language acquisition, using data from two children from the DuFDE-corpus (see Schlyter, 1990a), Christophe and Francois. Schlyter (1993, 1994) proposes that the "weaker" language in the unbalanced children she studied has the status…

  9. Unbalanced Nature, Unbounded Bodies, and Unlimited Technology: Ecocriticism and Karen Traviss' Wess'har Series

    ERIC Educational Resources Information Center

    Sullivan, Heather I.

    2010-01-01

    While nature is often claimed to be a space of harmonized balance or an antidote to the chaos of the modern world, we need a more grounded assessment of nature as endlessly changing and much less predictable than we like to assume. In this essay, I explore Karen Traviss' provocative exploration of unbalanced nature and unbounded bodies in her…

  10. Is This Object Balanced or Unbalanced? Judgments Are on the Safe Side

    ERIC Educational Resources Information Center

    Samuel, Francoise; Kerzel, Dirk

    2011-01-01

    Do we perceive correctly whether a 2-D object is balanced or unbalanced? What would be the cause of biased equilibrium judgments? In two psychometric studies, we varied independently the characteristics of the objects and the equilibrium states. First, we observed that observers were excessively sensitive to the eccentricity of the object top.…

  11. Characterization of human PGD blastocysts with unbalanced chromosomal translocations and human embryonic stem cell line derivation?

    PubMed

    Frydman, N; Féraud, O; Bas, C; Amit, M; Frydman, R; Bennaceur-Griscelli, A; Tachdjian, G

    2009-01-01

    Novel embryonic stem cell lines derived from embryos carrying structural chromosomal abnormalities obtained after preimplantation genetic diagnosis (PGD) are of interest to study in terms of the influence of abnormalities on further development. A total of 22 unbalanced blastocysts obtained after PGD were analysed for structural chromosomal defects. Morphological description and chromosomal status of these blastocysts was established and they were used to derive human embryonic stem cell (ESC) lines. An outgrowth of cells was observed for six blastocysts (6/22; 27%). For two blastocysts, the exact morphology was unknown since they were at early stage, and for four blastocysts, the inner cell mass was clearly visible. Fifteen blastocysts carried an unbalanced chromosomal defect linked to a reciprocal translocation, resulting in a positive outgrowth of cells for five blastocysts. One human ESC line was obtained from a blastocyst carrying a partial chromosome-21 monosomy and a partial chromosome-1 trisomy. Six blastocysts carried an unbalanced chromosomal defect linked to a Robertsonian translocation, and one showed a positive outgrowth of cells. One blastocyst carried an unbalanced chromosomal defect linked to an insertion and no outgrowth was observed. The efficiency of deriving human ESC lines with constitutional chromosomal disorders was low and probably depends on the initial morphological aspect of the blastocysts and/or the type of the chromosomal disorders.

  12. Disentangling electron- and electric-field-induced ring-closing reactions in a diarylethene derivative on Ag(1 1 1)

    NASA Astrophysics Data System (ADS)

    Reecht, Gaël; Lotze, Christian; Sysoiev, Dmytro; Huhn, Thomas; Franke, Katharina J.

    2017-07-01

    Using scanning tunneling microscopy and spectroscopy we investigate the adsorption properties and ring-closing reaction of a diarylethene derivative (C5F-4Py) on a Ag(1 1 1) surface. We identify an electron-induced reaction mechanism, with a quantum yield varying from 10-14-10-9 per electron upon variation of the bias voltage from 1-2 V. We ascribe the drastic increase in switching efficiency to a resonant enhancement upon tunneling through molecular orbitals. Additionally, we resolve the ring-closing reaction even in the absence of a current passing through the molecule. In this case the electric-field can modify the reaction barrier, leading to a finite switching probability at 4.8 K. A detailed analysis of the switching events shows that a simple plate-capacitor model for the tip-surface junction is insufficient to explain the distance dependence of the switching voltage. Instead, describing the tip as a sphere is in agreement with the findings. We resolve small differences in the adsorption configuration of the closed isomer, when comparing the electron- and field-induced switching product.

  13. Liquid metal-wetted niobium fiber brushes and braid close clearance collectors in magnetic fields comparison. Final report

    SciTech Connect

    Sondergaard, N.; Reilly, P.; Dilling, V.

    1993-08-01

    Niobium fiber brushes wetted with liquid metals offer an alternative to the highly successful braid collector because of the inherent flexibility of the metal fibers. A slipring of niobium fiber brushes wetted with NaK78 was compared directly with an NaK braid collector in a model of a 300-kW homopolar generator. Collector tip velocities varied from zero to 67 m/sec, currents from zero to 4,000 A, and magnetic fields from zero to 1.2 T. Results indicate under all conditions the fiber brush collector was comparable or superior to the braid collector. Current collector, Rectangular channel, Liquid metal flows, Power losses.

  14. Characterization of vertical electric fields and associated voltages induced on a overhead power line from close artificially initiated lightning

    NASA Astrophysics Data System (ADS)

    Rubinstein, Marcos; Uman, Martin A.; Thomson, Ewen M.; Medelius, Pedro J.

    1991-08-01

    Measurements were characterized of simultaneous vertical electric fields and voltages induced at both ends of a 448 m overhead power line by artificially initiated lightning return strokes. The lightning discharges struck ground about 20 m from one end of the line. The measured line voltages could be grouped into two categories: those in which multiple, similarly shaped, evenly spaced pulses were observed, which are called oscillatory; and those dominated by a principal pulse with subsidiary oscillations of much smaller amplitude, which are called impulsive. Voltage amplitudes range from tens of kilovolts for oscillatory voltages to hundreds of kilovolts for impulsive voltages.

  15. Characterization of vertical electric fields and associated voltages induced on a overhead power line from close artificially initiated lightning

    NASA Technical Reports Server (NTRS)

    Rubinstein, Marcos; Uman, Martin A.; Thomson, Ewen M.; Medelius, Pedro J.

    1991-01-01

    Measurements were characterized of simultaneous vertical electric fields and voltages induced at both ends of a 448 m overhead power line by artificially initiated lightning return strokes. The lightning discharges struck ground about 20 m from one end of the line. The measured line voltages could be grouped into two categories: those in which multiple, similarly shaped, evenly spaced pulses were observed, which are called oscillatory; and those dominated by a principal pulse with subsidiary oscillations of much smaller amplitude, which are called impulsive. Voltage amplitudes range from tens of kilovolts for oscillatory voltages to hundreds of kilovolts for impulsive voltages.

  16. Endotoxin deposits on the inner surfaces of closed-face cassettes during bioaerosol sampling: a field investigation at composting facilities.

    PubMed

    Duquenne, Philippe; Simon, Xavier; Demange, Valérie; Harper, Martin; Wild, Pascal

    2015-05-01

    A set of 270 bioaerosol samples was taken from 15 composting facilities using polystyrene closed-face filter cassettes (CFCs). The objective was to measure the quantity of endotoxin deposits on the inner surfaces of the cassettes (sometimes referred to as 'wall deposits'). The results show that endotoxins are deposited on the inner surfaces of the CFCs through sampling and/or handling of samples. The quantity of endotoxins measured on inner surfaces range between 0.05 (the limit of detection of the method) and 3100 endotoxin units per cassette. The deposits can represent a large and variable percentage of the endotoxins sampled. More than a third of the samples presented a percentage of inner surface deposits >40% of the total quantity of endotoxins collected (filter + inner surfaces). Omitting these inner surface deposits in the analytical process lead to measurement errors relative to sampling all particles entering the CFC sampler, corresponding to a developing consensus on matching the inhalable particulate sampling convention. The result would be underestimated exposures and could affect the decision as to whether or not a result is acceptable in comparison to airborne concentration limits defined in terms of the inhalability convention. The results of this study suggest including the endotoxins deposited on the inner surfaces of CFCs during analysis. Further researches are necessary to investigate endotoxin deposits on the inner cassette surfaces in other working sectors.

  17. Quantum manifestations of bifurcations of closed orbits in the photodetachment cross section of H- in parallel fields

    NASA Astrophysics Data System (ADS)

    Peters, A. D.; Jaffé, C.; Gao, J.; Delos, J. B.

    1997-07-01

    In the preceding paper, we showed that the semiclassical approximation diverges at a bifurcation, and that this divergence coincides with the passage of a focused cusp through the origin. Here we obtain a wave function in the vicinity of this cusp, and we use that wave function to eliminate the divergences in the photodetachment cross section. To describe the focused cusp, we first discuss the wave function of an ordinary two-dimensional (nonfocused) cusp. This wave function is known as a Pearcey function, and it has been studied extensively. Then we show how the formulas that lead to the Pearcey function have to be modified to describe a cylindrically focused cusp. The resulting wave function turns out to be given by an integral of Fresnel type containing within it a cylindrical Bessel function. This wave function is used to derive a formula for the photodetachment cross section near a bifurcation. That formula is a simple closed-form expression containing a Fresnel integral. Comparison with exact quantum calculations shows that this corrected-semiclassical formula is quite accurate.

  18. Low-frequency RF Coupling To Unconventional (Fat Unbalanced) Dipoles

    SciTech Connect

    Ong, M M; Brown, C G; Perkins, M P; Speer, R D; Javedani, J B

    2010-12-07

    The report explains radio frequency (RF) coupling to unconventional dipole antennas. Normal dipoles have thin equal length arms that operate at maximum efficiency around resonance frequencies. In some applications like high-explosive (HE) safety analysis, structures similar to dipoles with ''fat'' unequal length arms must be evaluated for indirect-lightning effects. An example is shown where a metal drum-shaped container with HE forms one arm and the detonator cable acts as the other. Even if the HE is in a facility converted into a ''Faraday cage'', a lightning strike to the facility could still produce electric fields inside. The detonator cable concentrates the electric field and carries the energy into the detonator, potentially creating a hazard. This electromagnetic (EM) field coupling of lightning energy is the indirect effect of a lightning strike. In practice, ''Faraday cages'' are formed by the rebar of the concrete facilities. The individual rebar rods in the roof, walls and floor are normally electrically connected because of the construction technique of using metal wire to tie the pieces together. There are two additional requirements for a good cage. (1) The roof-wall joint and the wall-floor joint must be electrically attached. (2) All metallic penetrations into the facility must also be electrically connected to the rebar. In this report, it is assumed that these conditions have been met, and there is no arcing in the facility structure. Many types of detonators have metal ''cups'' that contain the explosives and thin electrical initiating wires, called bridge wires mounted between two pins. The pins are connected to the detonator cable. The area of concern is between the pins supporting the bridge wire and the metal cup forming the outside of the detonator. Detonator cables usually have two wires, and in this example, both wires generated the same voltage at the detonator bridge wire. This is called the common-mode voltage. The explosive component

  19. A close-up view of Jupiter's magnetic field from Juno: New insights into the planet's deep interior

    NASA Astrophysics Data System (ADS)

    Jones, Chris A.; Holme, Richard

    2017-06-01

    The first results from the Juno mission magnetometer have recently become available. Juno provides us with the closest view of any planetary dynamo, flying to within 1.25 of the radius of the dynamo region, whereas for the Earth, we cannot get closer than 1.83 of the core-mantle boundary radius. We compare the Juno results with those from first principles dynamo simulations of Jupiter's magnetic field. Intense flux patches at Jupiter's surface are found in both the data and the simulations, though the simulations have them mainly at slightly higher latitudes than the observations. We consider the prospects for determining more accurately the location of the top of the metallic hydrogen region and the implications of possible weak flux patches at the poles.

  20. A close look on the lithosphere of Central North Africa with the new global gravity and gravity-gradient fields

    NASA Astrophysics Data System (ADS)

    Braitenberg, C. F.; Pivetta, T.; Mariani, P.

    2011-12-01

    The gravity satellite missions GRACE and GOCE have boosted the resolution of the global Earth gravity models (EGM), opening new possibilities of investigation. The EGMs must be distinguished in models based on pure satellite or mixed satellite-terrestrial observations. Satellite-only models are truly global, whereas satellite-terrestrial models have inhomogeneous quality, depending on availability and accuracy of the terrestrial data set. The advantage of the mixed models (e.g. EGM2008 by Pavlis et al. 2008) is their greater spatial resolution, reaching nominally 9 km, against the 80 km of the pure satellite models of satellite GOCE. The disadvantage is the geographically varying reliability due to problems in the terrestrial data, compiled from different measuring campaigns, using various acquisition methods, and different national geodetic reference systems. We present a method for quality assessment of the higher-resolution fields through the lower-resolution GOCE-field and apply it to northern Africa. We find that the errors locally are as great as 40 mGal, but can be flagged as "bad areas" by our method, leaving the "good areas" for reliable geophysical modeling and investigation. We analyze gravity and gravity gradients and their invariants over North-Central Africa derived from the EGM2008 and GOCE (e.g. Migliaccio et al., 2010) and quantify the resolution in terms of density variations associated to crustal thickness variations, rifts and magmatic underplating. We focus on the Benue rift and the Chad lineament, a 1300 km arcuate feature which links the Benue to the Tibesti Volcanic province. The existing seismological investigations are integrated to constrain the lithosphere structure in terms of seismic velocities, crustal thickness and top asthenosphere boundary, together with physical constraints based on thermal and isostatic considerations (McKenzie stretching model). Our modeling shows that the gravity signal can only be explained if the Benue rift

  1. Responses of the open-closed field line boundary in the evening sector to IMF changes: A source mechanism for Sun-aligned arcs

    NASA Astrophysics Data System (ADS)

    Maynard, N. C.; Burke, W. J.; Moen, J.; Ober, D. M.; Scudder, J. D.; Sigwarth, J. B.; Siscoe, G. L.; Sonnerup, B. U. Ã.-.; White, W. W.; Siebert, K. D.; Weimer, D. R.; Erickson, G. M.; Frank, L. A.; Lester, M.; Peterson, W. K.; Russell, C. T.; Wilson, G. R.; Egeland, A.

    2003-01-01

    Simultaneous measurements from the Polar satellite and by ground-based optical sensors suggest that brief variations of the poleward auroral boundary on the nightside correlate with changes in the interplanetary magnetic field (IMF) about an hour after a structure has propagated in the solar wind past the Earth. Short-lived Sun-aligned arcs may emerge along the open-closed magnetic field line boundary (OCB) and then disappear after ˜10 min. The arcs are fueled by energetic particles whose spectral characteristics are similar to those of the of boundary plasma sheet (BPS). Polar measurements confirm that these auroral protrusions into the polar cap occur on nearly isolated closed magnetic flux. Optical emissions from these arcs appear strongest at their intersection with the poleward boundary of the auroral oval. Detailed magnetohydrodynamic (MHD) simulations of dayside interactions, when the dominant IMF component BY changes sign, indicate that near the polarity reversal merging can occur between interplanetary field line segments within the magnetosheath [, 2001b]. Newly formed loops of interplanetary flux sweep past the Earth without interacting with the magnetosphere. Here, we consider some consequences within the distant magnetotail as the loops of disconnected flux propagate to XGSM ≈ -200 RE. The MHD simulations indicate that about an hour after intra-IMF merging events fingers of closed field lines protrude from the OCB into the polar cap. Like the observed Sun-aligned arc, these simulated auroral features grow and decay on scales of ˜10 min and have ionospheric footprints that are nearly surrounded by open magnetic flux. The simulated auroral fingers are conjugate to high-pressure channels in the distant plasma sheet. We suggest that the short-lived Sun-aligned arcs are created via an interchange process similar to that proposed by [1985] to explain one class of theta auroral forms. The continuity of magnetotail currents across a high-pressure channel

  2. Destruction of superconductivity and pseudogap closing in Bi2Sr2-xLaxCuO6+δ by 58 T magnetic field

    NASA Astrophysics Data System (ADS)

    Ono, S.; Balakirev, F. F.

    2005-03-01

    We measure the magnetic-field dependence of the c-axis resistivity ρc(H) in a series of Bi2Sr2-xLaxCuO6+δ (BSLCO) single crystals for a wide doping range using pulsed magnetic fields up to 58 T. [1] The behavior of ρc(H) is examined with the recent determination of the upper critical field Hc2 by the Nernst effect measurements for the same BSLCO crystals. We find that the peak in ρc(H) shows up at a field Hp that is much lower than Hc2 and there is no discernable feature in ρc(H) at Hc2. It is found that the doping dependence of Hp essentially track that of Tc. Moreover, a new method is proposed for estimating the pseudogap closing field Hpg from our BSLCO data, because we found that the method to estimate Hpg in Bi2Sr2CaCu2O8+δ [2] does not apply to our data. [1] S. Ono et al., cond-mat/0408603, To appear in PRB [2] T. Shibauchi et al. Phys. Rev. Lett. 86, 5763 (2001).

  3. Footprints of electron correlation in strong-field double ionization of Kr close to the sequential-ionization regime

    NASA Astrophysics Data System (ADS)

    Li, Xiaokai; Wang, Chuncheng; Yuan, Zongqiang; Ye, Difa; Ma, Pan; Hu, Wenhui; Luo, Sizuo; Fu, Libin; Ding, Dajun

    2017-09-01

    By combining kinematically complete measurements and a semiclassical Monte Carlo simulation we study the correlated-electron dynamics in the strong-field double ionization of Kr. Interestingly, we find that, as we step into the sequential-ionization regime, there are still signatures of correlation in the two-electron joint momentum spectrum and, more intriguingly, the scaling law of the high-energy tail is completely different from early predictions on the low-Z atom (He). These experimental observations are well reproduced by our generalized semiclassical model adapting a Green-Sellin-Zachor potential. It is revealed that the competition between the screening effect of inner-shell electrons and the Coulomb focusing of nuclei leads to a non-inverse-square central force, which twists the returned electron trajectory at the vicinity of the parent core and thus significantly increases the probability of hard recollisions between two electrons. Our results might have promising applications ranging from accurately retrieving atomic structures to simulating celestial phenomena in the laboratory.

  4. Estimation of Field depolarization and LSPR shift in closely packed metallic Nanoparticles with corrected plasmon line width

    NASA Astrophysics Data System (ADS)

    Arya, Mahima; Ranjan, Mukesh; Nath, Rabinder; Mitra, Anirban

    2017-10-01

    Using modified Yamaguchi model (MYM) along with wavelength dependent plasmon line-width correction, we have developed an analytical model which can calculate effective optical constants of any distribution of ellipsoidal nanoparticles using their morphological parameters. Present approach has been developed using exact expression of electric field outside an ellipsoid and thus the shape dependent interaction of nanoparticle for higher filling fraction has been calculated exactly. Limitations of widely used point dipole approximations and effective medium theories have been discussed and compared with present approach. Previously reported shape dependent expression for plasmon line-width has been incorporated to calculate effective optical constants of the array of nanoparticles system for in-plane and out of plane plasmons. Effect of interparticle distance has been discussed with the direction of polarization for various shapes of nanoparticles. Special case of ripple patterned supported elongated nanoparticles has been discussed and biaxial anisotropic behavior in optical constants of such structures has been understood analytically for the first time.

  5. 47 CFR 73.686 - Field strength measurements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... antenna impedance to the transmission line at all frequencies measured, and, if using an unbalanced line... transmission line between the testing antenna and the field strength meter. Match the antenna impedance to...

  6. Paleomagnetic Study of a Miocene Deformation in a Region Close to the Camargo Volcanic Field, Chihuahua, Mexico

    NASA Astrophysics Data System (ADS)

    Wogau-Chong, K.; Bohnel, H.; Aranda Gomez, J.

    2009-05-01

    The Sierra the Aguachile is a Miocene volcanic sequence located in the SE of Chihuahua State NW of the Camargo volcanic field and belongs to the Agua Mayo Group, which unconformably overlays Mesozoic calcareous units. The Sierra de Aguachile sequence defines a structure that may be interpreted as a plunging fold, which could be the result of a reactivation of the San Marcos Fault. This major fault is well known more to the east but may extend into the study area where it would be covered by the younger volcanic sequences; its main activity has been reported to be during the the Neocomian with reactivation phases in the Paleogene and Miocene. To test if the observed structure is the result of a tectonic deformation that happened after the emplacement of the volcanic sequence, a paleomagnetic study was carried out. A total of 14 sites were sampled from different parts of the structure, all in the capping ignimbrite layers. Site mean directions were determined using AF demagnetization. The fold test was applied to analyze if the remanence was acquired in situ or before the proposed folding. Precision parameters k before and after application of the tectonic corrections are 25.38 and 31.43, respectively. This indicates that the Sierra de Aguachile indeed was folded after emplacement of the ignimbrites, which restricts the age of the corresponding tectonic event to be younger than 31.3 +/- 0.7 Ma. Due to the gentle folding though, the difference in precision parameters is not significant at the 95% probability level.

  7. Did the Mississippian Lodgepole buildup at Dickinson Field (North Dakota) form as a gas seep ({open_quotes}vent{close_quotes}) community?

    SciTech Connect

    Longman, M.W.

    1996-10-01

    The Lower Mississippian Lodgepole carbonate buildup reservoir at Dickinson Field in Stark County, North Dakota, has been widely reported as being a Waulsortian (or Waulsortian-like) mound. The term {open_quotes}Waulsortian mound{close_quotes} is used for a variety of Early Mississippian carbonate buildups that share a number of features including an abundance of carbonate mud, a {open_quotes}framework{close_quotes} of organisms such as fenestrate bryozoans and crinoids that tended to trap or baffle sediment, and a general absence of marine-cemented reef framework. Although the age of the Lodgepole mound at Dickinson Field qualifies it to be a Waulsortian mound, petrographic study of cores reveals that the reservoir rocks are quite unlike those in true Waulsortian mounds. Instead of being dominated by carbonate mud, the Lodgepole mound core is dominated by marine cement. Furthermore, ostracods and microbial limestones are common in the mound core where they occur with crinoid debris and small amounts of bryozoan, coral, and brachiopod debris. The abundant microbial limestones and marine cement indicate that the Dickinson mound formed as a lithified reef on the sea floor rather than as a Waulsortian mud mound. The microbial limestones, marine cement, and common ostracods in the mount core, and the fact that the mound nucleated almost directly o top of the Bakken Shale, suggest that the Dickinson Lodgepole mound formed at the site of a submarine spring and gas seep.

  8. What drives health care expenditure?--Baumol's model of 'unbalanced growth' revisited.

    PubMed

    Hartwig, Jochen

    2008-05-01

    The share of health care expenditure in GDP rises rapidly in virtually all OECD countries, causing increasing concern among politicians and the general public. Yet, economists have to date failed to reach an agreement on what the main determinants of this development are. This paper revisits Baumol's [Baumol, W.J., 1967. Macroeconomics of unbalanced growth: the anatomy of urban crisis. American Economic Review 57 (3), 415-426] model of 'unbalanced growth', showing that the latter offers a ready explanation for the observed inexorable rise in health care expenditure. The main implication of Baumol's model in this context is that health care expenditure is driven by wage increases in excess of productivity growth. This hypothesis is tested empirically using data from a panel of 19 OECD countries. Our tests yield robust evidence in favor of Baumol's theory.

  9. Statistical analysis of efficient unbalanced factorial designs for two-color microarray experiments.

    PubMed

    Tempelman, Robert J

    2008-01-01

    Experimental designs that efficiently embed a fixed effects treatment structure within a random effects design structure typically require a mixed-model approach to data analyses. Although mixed model software tailored for the analysis of two-color microarray data is increasingly available, much of this software is generally not capable of correctly analyzing the elaborate incomplete block designs that are being increasingly proposed and used for factorial treatment structures. That is, optimized designs are generally unbalanced as it pertains to various treatment comparisons, with different specifications of experimental variability often required for different treatment factors. This paper uses a publicly available microarray dataset, as based upon an efficient experimental design, to demonstrate a proper mixed model analysis of a typical unbalanced factorial design characterized by incomplete blocks and hierarchical levels of variability.

  10. Statistical Analysis of Efficient Unbalanced Factorial Designs for Two-Color Microarray Experiments

    PubMed Central

    Tempelman, Robert J.

    2008-01-01

    Experimental designs that efficiently embed a fixed effects treatment structure within a random effects design structure typically require a mixed-model approach to data analyses. Although mixed model software tailored for the analysis of two-color microarray data is increasingly available, much of this software is generally not capable of correctly analyzing the elaborate incomplete block designs that are being increasingly proposed and used for factorial treatment structures. That is, optimized designs are generally unbalanced as it pertains to various treatment comparisons, with different specifications of experimental variability often required for different treatment factors. This paper uses a publicly available microarray dataset, as based upon an efficient experimental design, to demonstrate a proper mixed model analysis of a typical unbalanced factorial design characterized by incomplete blocks and hierarchical levels of variability. PMID:18584033

  11. Reduction of the unbalanced magnetic force of a transverse flux machine by using symmetric multipair cores

    NASA Astrophysics Data System (ADS)

    Jang, G. H.; Park, N. K.; Lee, C. I.; Chang, J. H.; Jeong, S. W.; Kang, D. H.

    2008-04-01

    This paper investigates the characteristics of the magnetic force and the torque in the conventional rotatory two-phase transverse flux machine (TFM) by using the three-dimensional finite element method. This research shows that the unbalanced magnetic force is one of the dominant excitation forces in this machine, and it proposes a TFM with symmetric multipair cores in which each stator core of phases A and B is divided into two and the divided cores are disposed symmetrically to cancel the unbalanced magnetic force of each phase of a TFM. However, symmetric multipair cores of a TFM may reduce the winding space of coil which results in the reduction of torque and power. This research performs the optimization of teeth-slot configuration of the stator to overcome this shortcoming. It shows that the unbalance magnetic force of a TFM can be effectively eliminated without sacrificing torque or power by introducing symmetric multipair cores.

  12. Frequency Noise Suppression of a Single Mode Laser with an Unbalanced Fiber Interferometer for Subnanometer Interferometry

    PubMed Central

    Šmíd, Radek; Čížek, Martin; Mikel, Břetislav; Číp, Ondřej

    2015-01-01

    We present a method of noise suppression of laser diodes by an unbalanced Michelson fiber interferometer. The unstabilized laser source is represented by compact planar waveguide external cavity laser module, ORIONTM (Redfern Integrated Optics, Inc.), working at 1540.57 nm with a 1.5-kHz linewidth. We built up the unbalanced Michelson interferometer with a 2.09 km-long arm based on the standard telecommunication single-mode fiber (SMF-28) spool to suppress the frequency noise by the servo-loop control by 20 dB to 40 dB within the Fourier frequency range, remaining the tuning range of the laser frequency. PMID:25587980

  13. A Parallel Biological Optimization Algorithm to Solve the Unbalanced Assignment Problem Based on DNA Molecular Computing

    PubMed Central

    Wang, Zhaocai; Pu, Jun; Cao, Liling; Tan, Jian

    2015-01-01

    The unbalanced assignment problem (UAP) is to optimally resolve the problem of assigning n jobs to m individuals (m < n), such that minimum cost or maximum profit obtained. It is a vitally important Non-deterministic Polynomial (NP) complete problem in operation management and applied mathematics, having numerous real life applications. In this paper, we present a new parallel DNA algorithm for solving the unbalanced assignment problem using DNA molecular operations. We reasonably design flexible-length DNA strands representing different jobs and individuals, take appropriate steps, and get the solutions of the UAP in the proper length range and O(mn) time. We extend the application of DNA molecular operations and simultaneity to simplify the complexity of the computation. PMID:26512650

  14. A Parallel Biological Optimization Algorithm to Solve the Unbalanced Assignment Problem Based on DNA Molecular Computing.

    PubMed

    Wang, Zhaocai; Pu, Jun; Cao, Liling; Tan, Jian

    2015-10-23

    The unbalanced assignment problem (UAP) is to optimally resolve the problem of assigning n jobs to m individuals (m < n), such that minimum cost or maximum profit obtained. It is a vitally important Non-deterministic Polynomial (NP) complete problem in operation management and applied mathematics, having numerous real life applications. In this paper, we present a new parallel DNA algorithm for solving the unbalanced assignment problem using DNA molecular operations. We reasonably design flexible-length DNA strands representing different jobs and individuals, take appropriate steps, and get the solutions of the UAP in the proper length range and O(mn) time. We extend the application of DNA molecular operations and simultaneity to simplify the complexity of the computation.

  15. Induced Unbalanced Linguistic Ordered Weighted Average and Its Application in Multiperson Decision Making

    PubMed Central

    Merigó, José M.

    2014-01-01

    Linguistic variables are very useful to evaluate alternatives in decision making problems because they provide a vocabulary in natural language rather than numbers. Some aggregation operators for linguistic variables force the use of a symmetric and uniformly distributed set of terms. The need to relax these conditions has recently been posited. This paper presents the induced unbalanced linguistic ordered weighted average (IULOWA) operator. This operator can deal with a set of unbalanced linguistic terms that are represented using fuzzy sets. We propose a new order-inducing criterion based on the specificity and fuzziness of the linguistic terms. Different relevancies are given to the fuzzy values according to their uncertainty degree. To illustrate the behaviour of the precision-based IULOWA operator, we present an environmental assessment case study in which a multiperson multicriteria decision making model is applied. PMID:25136677

  16. Improving the phase super-sensitivity of squeezing-assisted interferometers by squeeze factor unbalancing

    NASA Astrophysics Data System (ADS)

    Manceau, Mathieu; Khalili, Farid; Chekhova, Maria

    2017-01-01

    The sensitivity properties of an SU(1,1) interferometer made of two cascaded parametric amplifiers, as well as of an ordinary SU(2) interferometer preceded by a squeezer and followed by an anti-squeezer, are theoretically investigated. Several possible experimental configurations are considered, such as the absence or presence of a seed beam, direct or homodyne detection scheme. In all cases we formulate the optimal conditions to achieve phase super-sensitivity, meaning a sensitivity overcoming the shot-noise limit. We show that for a given gain of the first parametric amplifier, unbalancing the interferometer by increasing the gain of the second amplifier improves the interferometer properties. In particular, a broader super-sensitivity phase range and a better overall sensitivity can be achieved by gain unbalancing.

  17. Prader-Willi syndrome with an unusually large 15q deletion due to an unbalanced translocation t(4;15).

    PubMed

    Varela, Monica C; Lopes, Graziela M P; Koiffmann, Celia P

    2004-01-01

    Prader-Willi syndrome (PWS) is a neurobehavioral disorder caused by deletions in the 15q11-q13 region, by maternal uniparental disomy of chromosome 15 or by imprinting defects. Structural rearrangements of chromosome 15 have been described in about 5% of the patients with typical or atypical PWS phenotype. An 8-year-old boy with a clinical diagnosis of PWS, severe neurodevelopmental delay, absence of speech and mental retardation was studied by cytogenetic and molecular techniques, and an unbalanced de novo karyotype 45,XY,der(4)t(4;15)(q35;q14),-15 was detected after GTG-banding. The patient was diagnosed by SNURF-SNRPN exon 1 methylation assay, and the extent of the deletions on chromosomes 4 and 15 was investigated by microsatellite analysis of markers located in 4qter and 15q13-q14 regions. The deletion of chromosome 4q was distal to D4S1652, and that of chromosome 15 was located between D15S1043 and D15S1010. Our patient's severely affected phenotype could be due to the extent of the deletion, larger than usually seen in PWS patients, although the unbalance of the derivative chromosome 4 cannot be ruled out as another possible cause. The breakpoint was located in the subtelomeric region, very close to the telomere, a region that has been described as having the lowest gene concentrations in the human genome.

  18. Long-range distributed Brillouin fiber sensors by use of an unbalanced double sideband probe.

    PubMed

    Bernini, Romeo; Minardo, Aldo; Zeni, Luigi

    2011-11-21

    We propose and demonstrate a long-range Brillouin Optical Time-Domain Analysis (BOTDA) distributed sensing system making use of an unbalanced double sideband probe formed by a Stokes and an anti-Stokes line. In particular, we show that for each measuring condition an optimal Stokes /anti-Stokes input power ratio exists, allowing a larger suppression of nonlocal effects induced by pump depletion. Experiments on a 50 km single-mode sensing fiber with 5 meters spatial resolution are reported.

  19. A photonic analog-to-digital converter based on an unbalanced Mach-Zehnder quantizer.

    PubMed

    Sarantos, Chris H; Dagli, Nadir

    2010-07-05

    A Mach-Zehnder modulator (MZM) based analog to digital converter (ADC) is described. The signal to be digitized is applied to a single electrode of a high speed unbalanced modulator that acts as a quantizer. The rest of the system consists of commercially available wavelength division multiplexing (WDM) components. Analysis indicates that 6 bit operation at 40 Giga Samples per second (GS/s) is possible with moderate optical carrier power.

  20. Steady-State Modeling of Modular Multilevel Converter Under Unbalanced Grid Conditions

    DOE PAGES

    Shi, Xiaojie M.; Wang, Zhiqiang; Liu, Bo; ...

    2016-11-16

    This paper presents a steady-state model of MMC for the second-order phase voltage ripple prediction under unbalanced conditions, taking the impact of negative-sequence current control into account. From the steady-state model, a circular relationship is found among current and voltage quantities, which can be used to evaluate the magnitudes and initial phase angles of different circulating current components. Moreover, in order to calculate the circulating current in a point-to-point MMC-based HVdc system under unbalanced grid conditions, the derivation of equivalent dc impedance of an MMC is discussed as well. According to the dc impedance model, an MMC inverter can bemore » represented as a series connected R-L-C branch, with its equivalent resistance and capacitance directly related to the circulating current control parameters. Experimental results from a scaled-down three-phase MMC system under an emulated single-line-to-ground fault are provided to support the theoretical analysis and derived model. In conclusion, this new models provides an insight into the impact of different control schemes on the fault characteristics and improves the understanding of the operation of MMC under unbalanced conditions.« less

  1. Steady-State Modeling of Modular Multilevel Converter Under Unbalanced Grid Conditions

    SciTech Connect

    Shi, Xiaojie M.; Wang, Zhiqiang; Liu, Bo; Li, Yalong; Tolbert, Leon M.; Wang, Fred

    2016-11-16

    This paper presents a steady-state model of MMC for the second-order phase voltage ripple prediction under unbalanced conditions, taking the impact of negative-sequence current control into account. From the steady-state model, a circular relationship is found among current and voltage quantities, which can be used to evaluate the magnitudes and initial phase angles of different circulating current components. Moreover, in order to calculate the circulating current in a point-to-point MMC-based HVdc system under unbalanced grid conditions, the derivation of equivalent dc impedance of an MMC is discussed as well. According to the dc impedance model, an MMC inverter can be represented as a series connected R-L-C branch, with its equivalent resistance and capacitance directly related to the circulating current control parameters. Experimental results from a scaled-down three-phase MMC system under an emulated single-line-to-ground fault are provided to support the theoretical analysis and derived model. In conclusion, this new models provides an insight into the impact of different control schemes on the fault characteristics and improves the understanding of the operation of MMC under unbalanced conditions.

  2. Radio-frequency unbalanced M-Z interferometer for wavelength interrogation of fiber Bragg grating sensors.

    PubMed

    Zhou, Jiaao; Xia, Li; Cheng, Rui; Wen, Yongqiang; Rohollahnejad, Jalal

    2016-01-15

    The optical unbalanced Mach-Zehnder interferometer (UMZI) has attracted significant interests for interrogation of FBG sensors owing to its excellent advantages in sensitivity, resolution, and demodulation speed. But this method is still limited to dynamic measurements due to its poor stability and reliability when used for quasi-static detections. Here, we propose for the first time, to the best of our knowledge, a radio-frequency unbalanced M-Z interferometer (RF-UMZI) for interrogation of FBG sensors, which, owing to its operation in an incoherent rather than a coherent regime, provides an ideal solution for the existing stability problem of the conventional UMZI, with remarkable features of adjustable resolution and potentially extremely high sensitivity. A dispersion compensation fiber (DCF) and single-mode fiber (SMF) with a small length difference are served as the two unbalanced arms of the RF interferometer. The induced differential chromatic dispersion transfers the wavelength shift of the FBG to the change of the RF phase difference between the two interferometric carriers, which ultimately leads to the variation of the RF signal intensity. An interrogation of a strain-turned FBG was accomplished and a maximum sensitivity of 0.00835  a.u./με was obtained, which can easily be further improved by more than two orders of magnitude through various fiber dispersion components. Finally, the stability of the interrogation was tested.

  3. Three-Phase Unbalanced Transient Dynamics and Powerflow for Modeling Distribution Systems With Synchronous Machines

    SciTech Connect

    Elizondo, Marcelo A.; Tuffner, Francis K.; Schneider, Kevin P.

    2016-01-01

    Unlike transmission systems, distribution feeders in North America operate under unbalanced conditions at all times, and generally have a single strong voltage source. When a distribution feeder is connected to a strong substation source, the system is dynamically very stable, even for large transients. However if a distribution feeder, or part of the feeder, is separated from the substation and begins to operate as an islanded microgrid, transient dynamics become more of an issue. To assess the impact of transient dynamics at the distribution level, it is not appropriate to use traditional transmission solvers, which generally assume transposed lines and balanced loads. Full electromagnetic solvers capture a high level of detail, but it is difficult to model large systems because of the required detail. This paper proposes an electromechanical transient model of synchronous machine for distribution-level modeling and microgrids. This approach includes not only the machine model, but also its interface with an unbalanced network solver, and a powerflow method to solve unbalanced conditions without a strong reference bus. The presented method is validated against a full electromagnetic transient simulation.

  4. A Serially-Connected Compensator for Eliminating the Unbalanced Three-Phase Voltage Impact on Wind Turbine Generators

    SciTech Connect

    Wu, Ziping; Hsu, Ping; Muljadi, Eduard; Gao, Wenzhong

    2015-10-05

    Untransposed transmission lines, unbalanced tap changer operations, and unbalanced loading in weak distribution lines can cause unbalanced-voltage conditions. The resulting unbalanced voltage at the point of interconnection affects proper gird integration and reduces the lifetime of wind turbines due to power oscillations, torque pulsations, mechanical stresses, energy losses, and uneven and overheating of the generator stator winding. This work investigates the dynamic impact of unbalanced voltage on the mechanical and electrical components of integrated Fatigue, Aerodynamics, Structures, and Turbulence (FAST) wind turbine generation systems (WTGs) of Type 1 (squirrel-cage induction generator) and Type 3 (doubly-fed induction generator). To alleviate this impact, a serially-connected compensator for a three-phase power line is proposed to balance the wind turbine-side voltage. Dynamic simulation studies are conducted in MATLAB/Simulink to compare the responses of these two types of wind turbine models under normal and unbalanced-voltage operation conditions and demonstrate the effectiveness of the proposed compensator.

  5. Serially-Connected Compensator for Eliminating the Unbalanced Three-Phase Voltage Impact on Wind Turbine Generators: Preprint

    SciTech Connect

    Wu, Z.; Hsu, P.; Muljadi, E.; Gao, W.

    2015-04-06

    Untransposed transmission lines, unbalanced tap changer operations, and unbalanced loading in weak distribution lines can cause unbalanced-voltage conditions. The resulting unbalanced voltage at the point of interconnection affects proper gird integration and reduces the lifetime of wind turbines due to power oscillations, torque pulsations, mechanical stresses, energy losses, and uneven and overheating of the generator stator winding. This work investigates the dynamic impact of unbalanced voltage on the mechanical and electrical components of integrated Fatigue, Aerodynamics, Structures, and Turbulence (FAST) wind turbine generation systems (WTGs) of Type 1 (squirrel-cage induction generator) and Type 3 (doubly-fed induction generator). To alleviate this impact, a serially-connected compensator for a three-phase power line is proposed to balance the wind turbine-side voltage. Dynamic simulation studies are conducted in MATLAB/Simulink to compare the responses of these two types of wind turbine models under normal and unbalanced-voltage operation conditions and demonstrate the effectiveness of the proposed compensator.

  6. Closed-loop stimulation of a delayed neural fields model of parkinsonian STN-GPe network: a theoretical and computational study

    PubMed Central

    Detorakis, Georgios Is.; Chaillet, Antoine; Palfi, Stéphane; Senova, Suhan

    2015-01-01

    Several disorders are related to pathological brain oscillations. In the case of Parkinson's disease, sustained low-frequency oscillations (especially in the β-band, 13–30 Hz) correlate with motor symptoms. It is still under debate whether these oscillations are the cause of parkinsonian motor symptoms. The development of techniques enabling selective disruption of these β-oscillations could contribute to the understanding of the underlying mechanisms, and could be exploited for treatments. A particularly appealing technique is Deep Brain Stimulation (DBS). With clinical electrical DBS, electrical currents are delivered at high frequency to a region made of potentially heterogeneous neurons (the subthalamic nucleus (STN) in the case of Parkinson's disease). Even more appealing is DBS with optogenetics, which is until now a preclinical method using both gene transfer and deep brain light delivery and enabling neuromodulation at the scale of one given neural network. In this work, we rely on delayed neural fields models of STN and the external Globus Pallidus (GPe) to develop, theoretically validate and test in silico a closed-loop stimulation strategy to disrupt these sustained oscillations with optogenetics. First, we rely on tools from control theory to provide theoretical conditions under which sustained oscillations can be attenuated by a closed-loop stimulation proportional to the measured activity of STN. Second, based on this theoretical framework, we show numerically that the proposed closed-loop stimulation efficiently attenuates sustained oscillations, even in the case when the photosensitization effectively affects only 50% of STN neurons. We also show through simulations that oscillations disruption can be achieved when the same light source is used for the whole STN population. We finally test the robustness of the proposed strategy to possible acquisition and processing delays, as well as parameters uncertainty. PMID:26217171

  7. Closed-loop stimulation of a delayed neural fields model of parkinsonian STN-GPe network: a theoretical and computational study.

    PubMed

    Detorakis, Georgios Is; Chaillet, Antoine; Palfi, Stéphane; Senova, Suhan

    2015-01-01

    Several disorders are related to pathological brain oscillations. In the case of Parkinson's disease, sustained low-frequency oscillations (especially in the β-band, 13-30 Hz) correlate with motor symptoms. It is still under debate whether these oscillations are the cause of parkinsonian motor symptoms. The development of techniques enabling selective disruption of these β-oscillations could contribute to the understanding of the underlying mechanisms, and could be exploited for treatments. A particularly appealing technique is Deep Brain Stimulation (DBS). With clinical electrical DBS, electrical currents are delivered at high frequency to a region made of potentially heterogeneous neurons (the subthalamic nucleus (STN) in the case of Parkinson's disease). Even more appealing is DBS with optogenetics, which is until now a preclinical method using both gene transfer and deep brain light delivery and enabling neuromodulation at the scale of one given neural network. In this work, we rely on delayed neural fields models of STN and the external Globus Pallidus (GPe) to develop, theoretically validate and test in silico a closed-loop stimulation strategy to disrupt these sustained oscillations with optogenetics. First, we rely on tools from control theory to provide theoretical conditions under which sustained oscillations can be attenuated by a closed-loop stimulation proportional to the measured activity of STN. Second, based on this theoretical framework, we show numerically that the proposed closed-loop stimulation efficiently attenuates sustained oscillations, even in the case when the photosensitization effectively affects only 50% of STN neurons. We also show through simulations that oscillations disruption can be achieved when the same light source is used for the whole STN population. We finally test the robustness of the proposed strategy to possible acquisition and processing delays, as well as parameters uncertainty.

  8. Evaluating the effect of unbalanced data in biomedical document classification.

    PubMed

    Laza, Rosalía; Pavón, Reyes; Reboiro-Jato, Miguel; Fdez-Riverola, Florentino

    2011-09-16

    Nowadays, document classification has become an interesting research field. Partly, this is due to the increasing availability of biomedical information in digital form which is necessary to catalogue and organize. In this context, machine learning techniques are usually applied to text classification by using a general inductive process that automatically builds a text classifier from a set of pre-classified documents. Related with this domain, imbalanced data is a well-known problem in many practical applications of knowledge discovery and its effects on the performance of standard classifiers are remarkable. In this paper, we investigate the application of a Bayesian Network (BN) model for the triage of documents, which are represented by the association of different MeSH terms. Our results show that BNs are adequate for describing conditional independencies between MeSH terms and that MeSH ontology is a valuable resource for representing Medline documents at different abstraction levels. Moreover, we perform an extensive experimental evaluation to investigate if the classification of Medline documents using a BN classifier poses additional challenges when dealing with class-imbalanced prediction. The evaluation involves two methods, under-sampling and cost-sensitive learning. We conclude that BN classifier is sensitive to both balancing strategies and existing techniques can improve its overall performance. Copyright 2011 The Author(s). Published by Journal of Integrative Bioinformatics.

  9. Closing in on Close Reading

    ERIC Educational Resources Information Center

    Boyles, Nancy

    2013-01-01

    "A significant body of research links the close reading of complex text--whether the student is a struggling reader or advanced--to significant gains in reading proficiency and finds close reading to be a key component of college and career readiness" (Partnership for Assessment of Readiness for College and Careers, 2011, p. 7). When the author…

  10. Multipoint observations of the open-closed field line boundary as observed by the Van Allen Probes and geostationary satellites during the 14 November 2012 geomagnetic storm

    NASA Astrophysics Data System (ADS)

    Dixon, P.; MacDonald, E. A.; Funsten, H. O.; Glocer, A.; Grande, M.; Kletzing, C.; Larsen, B. A.; Reeves, G.; Skoug, R. M.; Spence, H.; Thomsen, M. F.

    2015-08-01

    The twin Van Allen Probes spacecraft witnessed a series of lobe encounters between 0200 and 0515 UT on 14 November 2012. Although lobe entry had been observed previously by other spacecraft, the two Van Allen Probe spacecraft allow us to observe the motion of the boundary for the first time. Moreover, this event is unique in that it consists of a series of six quasi-periodic lobe entries. The events occurred on the dawn flank between 4 and 6.6 local time and at altitudes between 5.6 and 6.2 RE. During the events Dst dropped to less than -100nT with the IMF being strongly southward (Bz = -15nT) and eastward (By = 20 nT). Observations by LANL-GEO spacecraft at geosynchronous orbit also show lobe encounters on the dawn and dusk flanks. The two spacecraft configuration provides strong evidence that these periodic entries into the lobe are the result of local expansions of the OCB propagating from the tail and passing over the Van Allen Probes. Examination of pitch angle binned data from the HOPE instrument shows spatially large, accelerated ion structures occurring near simultaneously at both spacecraft, with the presence of oxygen indicating that they have an ionospheric source. The outflows are dispersed in energy and are detected when the spacecraft are on both open and closed field lines. These events provide a chance to examine the global magnetic field topology in detail, as well as smaller-scale spatial and temporal characteristics of the OCB, allowing us to constrain the position of the open/closed field line boundary and compare it to a global MHD model using a novel method. This technique shows that the model can reproduce a periodic approach and retreat of the OCB from the spacecraft but can overestimate its distance by as much as 3 RE. The model appears to simulate the dynamic processes that cause the spacecraft to encounter the lobe but incorrectly maps the overall topology of the magnetosphere during these extreme conditions.

  11. Analysis of frequency noise properties of 729nm extended cavity diode laser with unbalanced Mach-Zehnder interferometer

    NASA Astrophysics Data System (ADS)

    Pham, Tuan M.; Čížek, Martin; Hucl, Václav; Lazar, Josef; Hrabina, Jan; Řeřucha, Šimon; Lešundák, Adam; Obšil, Petr; Filip, Radim; Slodička, Lukáš; Číp, Ondřej

    2016-12-01

    We report on the frequency noise investigation of a linewidth-suppressed Extended Cavity Diode Laser (ECDL), working at 729 nm. Since the ECDL is intended as an excitation laser for the forbidden transition in a trapped and laser cooled 40Ca+ ion, an Hz-level linewidth is required. We present the experimental design that comprises a two-stage linewidth narrowing and a facility for frequency and noise analysis. The linewidth is first narrowed with a phase lock loop of the ECDL onto a selected component of an optical frequency comb where the frequency noise was suppressed with a fast electronic servo-loop controller that drives the laser injection current with a high bandwidth. The second stage comprises locking the laser onto a selected mode of a high-finesse passive optical cavity. The frequency analysis used an unbalanced Mach-Zehnder interferometer with a fiber spool inserted in the reference arm in order to give a general insight into the signal properties by mixing two separated beams, one of them delayed by the spool, and processing it with a spectral analyzer. Such a frequency noise analysis reveals what are the most significant noises contributions to the laser linewidth, which is a crucial information in field of ion trapping and cooling. The presented experimental results show the effect of the linewidth narrowing with the first stage, where the linewidth of ECDL was narrowed down to a kHz level.

  12. Closing remarks

    PubMed Central

    Daykin, C. D.

    1997-01-01

    Closing remarks to Human genetics - uncertainties and the financial implications ahead. A Discussion held at the Royal Society on 25 and 26 September 1996, and organized and edited by R. M. Anderson.

  13. Numerically-simulated induced electric field and current density within a human model located close to a z-gradient coil.

    PubMed

    Li, Yan; Hand, Jeff W; Wills, Tim; Hajnal, Jo V

    2007-11-01

    To simulate exposure (e.g., during interventional procedures) of a worker close to an operating MR scanner by calculating electric fields and current density within an anatomically realistic body model due to a z-gradient coil and to compare results with safety guidelines and European Directive 2004/40/EC. Electric field and current density in an adult male model located at three positions within the range 0.19-0.44 m from the end of a generic z-gradient coil were calculated using the time-domain finite integration technique (FIT). Frequency scaling was used in which quasistatic conditions were assumed and results obtained at 1 MHz (assuming tissue conductivity values at 1 kHz) were scaled to 1 kHz. Current density (averaged over 1 cm(2)) in central nervous system (CNS) tissues up to 20.6 mA m(-2) and electric fields (averaged over 5 mm) up to 4.1 V m(-1) were predicted for a gradient of 10 mT m(-1) and slew rate of 10 T m(-1) second(-1). Compliance with 2004/40/EC, and with basic restriction values of Institute of Electrical and Electronics Engineers (IEEE) C95.6-2002, was predicted only at impracticably low gradients/slew rates in the ranges 4.9-9.1 mT m(-1)/4.9-9.1 T m(-1) second(-1) and 5-21 mT m(-1)/5-21 T m(-1) second(-1), respectively.

  14. The role of the altruistic unbalanced chain in exchange living donor renal transplantation: single-center experience.

    PubMed

    Ahn, B K; Kwon, O J; Kang, C M

    2012-01-01

    The exchange donor program in renal transplantation is an efficient solution for recipients with a blood type or crossmatch-incompatible donor. However, this program has some difficulties to define unacceptable human leukocyte antigen matches, deteriorating clinical potential recipient condition, and withdrawal of donor consent. We analyzed the outcomes of exchange donor renal transplantation through the altruistic unbalanced chain. Among 152 cases of exchange donor renal transplantation from 1991 to 2010 in our hospital, we performed 58 procedures through altruistic unbalanced chains. We compared their outcomes with the direct and balanced chain group. We analyzed retrospectively whether this program expanded the donor pool, seeking better immunologic, size, and age matching. The graft survival and acute rejection rates did not differ significantly in the two groups. Of 152 cases, 58 (38.2%) renal transplantations were performed through an unbalanced chain. Seventeen waiting list recipients were transplanted through an altruistic unbalanced chain. In blood type O recipients (n = 32), the causes of registration in the exchange program were ABO incompatibility (93.3%), and positive crossmatch (6.7%). Nine altruistic blood type O donors and 9 (28.1%) type O recipients underwent transplantations through this chain. We suggest the altruistic unbalanced chain may expand the donor pool with advantages for difficult-to-match pairs. The disadvantages of type O recipients may be overcome through the use of an unbalanced chain. The altruistic unbalanced exchange transplantation program can help easy-to-match subjects, shortening the waiting periods. Copyright © 2012 Elsevier Inc. All rights reserved.

  15. Genetic Diversity and Biological Control Activity of Novel Species of Closely Related Pseudomonads Isolated from Wheat Field Soils in South Australia

    PubMed Central

    Ross, Ian L.; Alami, Younes; Harvey, Paul R.; Achouak, Wafa; Ryder, Maarten H.

    2000-01-01

    Rhizobacteria closely related to two recently described species of pseudomonads, Pseudomonas brassicacearum and Pseudomonas thivervalensis, were isolated from two geographically distinct wheat field soils in South Australia. Isolation was undertaken by either selective plating or immunotrapping utilizing a polyclonal antibody raised against P. brassicacearum. A subset of 42 isolates were characterized by amplified 16S ribosomal DNA restriction analysis (ARDRA), BIOLOG analysis, and gas chromatography-fatty acid methyl ester (GC-FAME) analysis and separated into closely related phenetic groups. More than 75% of isolates tested by ARDRA were found to have >95% similarity to either Pseudomonas corrugata or P. brassicacearum-P. thivervalensis type strains, and all isolates had >90% similarity to either type strain. BIOLOG and GC-FAME clustering showed a >70% match to ARDRA profiles. Strains representing different ARDRA groups were tested in two soil types for biological control activity against the soilborne plant pathogen Gaeumannomyces graminis var. tritici, the causative agent of take-all of wheat and barley. Three isolates out of 11 significantly reduced take-all-induced root lesions on wheat plants grown in a red-brown earth soil. Only one strain, K208, was consistent in reducing disease symptoms in both the acidic red-brown earth and a calcareous sandy loam. Results from this study indicate that P. brassicacearum and P. thivervalensis are present in Australian soils and that a level of genetic diversity exists within these two novel species but that this diversity does not appear to be related to geographic distribution. The result of the glasshouse pot trial suggests that some isolates of these species may have potential as biological control agents for plant disease. PMID:10742249

  16. Unbalanced 5;16 translocation in a boy with papillary thyroid carcinoma

    SciTech Connect

    McDonald, M.; Maynard, S.; Sheldon, S.; Innis, J.

    1994-02-01

    This is the first reported case of an unbalanced chromosome rearrangement resulting in trisomy 5q35.5{r_arrow}qter and monosomy 16p 13.3{r_arrow}pter, in a boy with mental and growth retardation, minor anomalies, and a history of bilateral papillary thyroid carcinoma. This was the result of a familial balanced translocation. The clinical and cytogenetic manifestations of the case are presented and the possible role of the chromosomal rearrangement in the etiology of the thyroid carcinoma is discussed. 25 refs., 5 figs., 1 tab.

  17. Performance of unbalanced QPSK in the presence of noisy reference and crosstalk

    NASA Technical Reports Server (NTRS)

    Divsalar, D.; Yuen, J. H.

    1979-01-01

    The problem of transmitting two telemetry data streams having different rates and different powers using unbalanced quadriphase shift keying (UQPSK) signaling is considered. It is noted that the presence of a noisy carrier phase reference causes a degradation in detection performance in coherent communications systems and that imperfect carrier synchronization not only attenuates the main demodulated signal voltage in UQPSK but also produces interchannel interference (crosstalk) which degrades the performance still further. Exact analytical expressions for symbol error probability of UQPSK in the presence of noise phase reference are derived.

  18. Suppression of frequency noise of single mode laser with unbalanced fiber interferometer for subnanometer interferometry

    NASA Astrophysics Data System (ADS)

    Šmíd, Radek; Čížek, Martin; Mikel, Břetislav; Lazar, Josef; Číp, Ondrej

    2014-05-01

    We present a method of noise suppression of laser diodes by unbalanced Michelson fiber interferometer. The unstabilized laser source is represented by compact planar waveguide external cavity laser module ORION (Redfern Integrated Optics, Inc.) working at 1040.57 nm with < 3 kHz linewidth. We built Michelson interferometer with 1 km long arm based on SMF-28 fiber spool to suppress the frequency noise by fast PI servo-loop up to 33 kHz of laser injection current modulation. We were able to decrease the noise level by -60 dBc/Hz up to 1.5 kHz noise frequency of the laser.

  19. Optimal contrast function in the unbalanced fiber optic Michelson interferometer for dislocation sensor

    NASA Astrophysics Data System (ADS)

    Szustakowski, Mieczyslaw; Palka, Norbert; Ciurapinski, Wieslaw M.

    2004-09-01

    Theoretical description of a contrast in an unbalanced fiber optic Michelson's interferometer with a multimode laser was shown. Periodic contrast oscillations, which depend on a laser spectrum, occur if a measuring arm of the interferometer is elongated. Required characteristic features of the contrast for an elongation sensor were determined. Influences of laser spectrum parameters (wavelength, halfwidth and mode spacing) as well as laser mode amplitudes on the contrast were simulated. Optimal spectrum for the dislocation sensor was determined theoretically. A laser which parameters fulfilled the requirements was found and its spectrum was measured. The measured contrast function was very similar to the optimal theoretical plot what proves correctness of the calculations.

  20. Unbalanced Michelson's interferometer as a fiber optic distributed sensor of external signals

    NASA Astrophysics Data System (ADS)

    Chojnacki, M.; Szustakowski, Mieczyslaw; Zyczkowski, Marek

    2001-08-01

    The subject of this work is a novel fiber optic distributed sensor system. The system uses a technique called multiplexed reflectometric interferometry to measure dynamic strain in a network of single mode optical fiber sensors. The sensor is constructed on unbalanced fiber optic Michelson's interferometer is activated by series of double pulse. The time interval between those pulses depends on the length of the section of sensor. Acousto-optical modulator acts as an optical frequency shifter. A change in a frequency of electrical pulses exciting the modulator result in a frequency shift in each generated wave packet.

  1. Rabi-oscillation-induced π phase flip in an unbalanced Ramsey atom interferometer

    NASA Astrophysics Data System (ADS)

    Li, R. B.; Yao, Z. W.; Wang, K.; Lu, S. B.; Cao, L.; Wang, J.; Zhan, M. S.

    2016-09-01

    We present an observation of zero-to-π phase flips induced by Rabi oscillation in an unbalanced Ramsey atom interferometer. The phase shift and visibility are experimentally investigated by modulating either the polarization or duration of Raman lasers, and they are well explained by a theoretical model. In an atom interferometer, the π phase flips are caused not only by the sign of Rabi frequency but also by the Rabi oscillation. Considering the π phase flips, we propose the composite-light-pulse sequences for realizing the large-momentum-transfer beam splitter and mirror, which have the high immunity to the external phase noise in building the cold atom interferometer.

  2. Secondary wavelength stabilization of unbalanced Michelson interferometers for the generation of low-jitter pulse trains.

    PubMed

    Shalloo, R J; Corner, L

    2016-09-01

    We present a double unbalanced Michelson interferometer producing up to four output pulses from a single input pulse. The interferometer is stabilized with the Hänsch-Couillaud method using an auxiliary low power continuous wave laser injected into the interferometer, allowing the stabilization of the temporal jitter of the output pulses to 0.02 fs. Such stabilized pulse trains would be suitable for driving multi-pulse laser wakefield accelerators, and the technique could be extended to include amplification in the arms of the interferometer.

  3. On the use of IMAGE FUV for estimating the latitude of the open/closed magnetic field line boundary in the ionosphere

    NASA Astrophysics Data System (ADS)

    Boakes, P. D.; Milan, S. E.; Abel, G. A.; Freeman, M. P.; Chisham, G.; Hubert, B.; Sotirelis, T.

    2008-09-01

    A statistical comparison of the latitude of the open/closed magnetic field line boundary (OCB) as estimated from the three far ultraviolet (FUV) detectors onboard the IMAGE spacecraft (the Wideband Imaging camera, WIC, and the Spectrographic Imagers, SI-12 and SI-13) has been carried out over all magnetic local times. A total of over 400 000 OCB estimations were compared from December 2000 and January and December of 2001 2002. The modal latitude difference between the FUV OCB proxies from the three detectors is small, <1°, except in the predawn and evening sectors, where the SI-12 OCB proxy is found to be displaced from both the SI-13 and WIC OCB proxies by up to 2° poleward in the predawn sector and by up to 2° equatorward in the evening sector. Comparing the IMAGE FUV OCB proxies with that determined from particle precipitation measurements by the Defense Meteorological Satellites Program (DMSP) also shows systematic differences. The SI-12 OCB proxy is found to be at higher latitude in the predawn sector, in better agreement with the DMSP OCB proxy. The WIC and SI-13 OCB proxies are found to be in better agreement with the DMSP OCB proxy at most other magnetic local times. These systematic offsets may be used to correct FUV OCB proxies to give a more accurate estimate of the OCB latitude.

  4. Gray mold populations in german strawberry fields are resistant to multiple fungicides and dominated by a novel clade closely related to Botrytis cinerea.

    PubMed

    Leroch, Michaela; Plesken, Cecilia; Weber, Roland W S; Kauff, Frank; Scalliet, Gabriel; Hahn, Matthias

    2013-01-01

    The gray mold fungus Botrytis cinerea is a major threat to fruit and vegetable production. Strawberry fields usually receive several fungicide treatments against Botrytis per season. Gray mold isolates from several German strawberry-growing regions were analyzed to determine their sensitivity against botryticides. Fungicide resistance was commonly observed, with many isolates possessing resistance to multiple (up to six) fungicides. A stronger variant of the previously described multidrug resistance (MDR) phenotype MDR1, called MDR1h, was found to be widely distributed, conferring increased partial resistance to two important botryticides, cyprodinil and fludioxonil. A 3-bp deletion mutation in a transcription factor-encoding gene, mrr1, was found to be correlated with MDR1h. All MDR1h isolates and the majority of isolates with resistance to multiple fungicides were found to be genetically distinct. Multiple-gene sequencing confirmed that they belong to a novel clade, called Botrytis group S, which is closely related to B. cinerea and the host-specific species B. fabae. Isolates of Botrytis group S genotypes were found to be widespread in all German strawberry-growing regions but almost absent from vineyards. Our data indicate a clear subdivision of gray mold populations, which are differentially distributed according to their host preference and adaptation to chemical treatments.

  5. Signatures of the nightside open-closed magnetic field-line boundary during a moderately disturbed interval and an ionospheric substorm

    NASA Astrophysics Data System (ADS)

    Parkinson, M.; Pinnock, M.; Dyson, P.; Devlin, J.

    The comparatively low latitude of the Tasman International Geospace Environment Radar (147.2°E, 43.4°S, geographic; -54.6°) a Southern Hemisphere HF SuperDARN radar, facilitates the observation of extensive backscatter from decametre-scale irregularities drifting in the auroral and polar cap ionosphere in the pre-midnight sector. The radar often detects a persistent, sharp latitudinal decrease (~90 km) in line-of-sight Doppler velocity spread, or spectral width, from >200 m s-1 in the polar cap ionosphere, to <50 m s-1 in the auroral ionosphere. The location of this spectral width boundary (SWB) matches the poleward edge of the auroral oval determined using energy spectra of precipitating particles measured on board Defence Meteorology Satellite Program satellites. This implies the radar SWB is a reasonable proxy for the open-closed magnetic field-line boundary (OCB). The location of the SWB fluctuates on a spread of time scales, expanding equatorward or contracting poleward, much as would be expected when dayside or nightside reconnection dominate the nightside flows, respectively. Here we investigate how accurately the radar SWB is aligned with the satellite OCB during moderately disturbed geomagnetic conditions, and a substorm. For example, does the alignment of the radar SWB with the OCB change with magnetic local time and geomagnetic activity? Down to what spatial and temporal scales is the radar SWB an accurate proxy for the satellite OCB?

  6. Gray Mold Populations in German Strawberry Fields Are Resistant to Multiple Fungicides and Dominated by a Novel Clade Closely Related to Botrytis cinerea

    PubMed Central

    Leroch, Michaela; Plesken, Cecilia; Weber, Roland W. S.; Kauff, Frank; Scalliet, Gabriel

    2013-01-01

    The gray mold fungus Botrytis cinerea is a major threat to fruit and vegetable production. Strawberry fields usually receive several fungicide treatments against Botrytis per season. Gray mold isolates from several German strawberry-growing regions were analyzed to determine their sensitivity against botryticides. Fungicide resistance was commonly observed, with many isolates possessing resistance to multiple (up to six) fungicides. A stronger variant of the previously described multidrug resistance (MDR) phenotype MDR1, called MDR1h, was found to be widely distributed, conferring increased partial resistance to two important botryticides, cyprodinil and fludioxonil. A 3-bp deletion mutation in a transcription factor-encoding gene, mrr1, was found to be correlated with MDR1h. All MDR1h isolates and the majority of isolates with resistance to multiple fungicides were found to be genetically distinct. Multiple-gene sequencing confirmed that they belong to a novel clade, called Botrytis group S, which is closely related to B. cinerea and the host-specific species B. fabae. Isolates of Botrytis group S genotypes were found to be widespread in all German strawberry-growing regions but almost absent from vineyards. Our data indicate a clear subdivision of gray mold populations, which are differentially distributed according to their host preference and adaptation to chemical treatments. PMID:23087030

  7. A comparison of linear and exponential regression for estimating diffusive methane fluxes by closed-chamber - results from laboratory and field campaigns

    NASA Astrophysics Data System (ADS)

    Schreiber, P.; Forbrich, I.; Kutzbach, L.; Hormann, A.; Wolf, U.; Miglovec, M.; Pihlatie, M.; Christiansen, J. R.; Wilmking, M.

    2009-04-01

    Closed chambers are the most common method to determine methane (CH4) fluxes in peatlands. The concentration change over time is monitored, and the flux is usually calculated by the slope of a linear regression function. However, chambers tend to slow down the gas diffusion by changing the concentration gradient between soil and atmosphere. Theoretically, this would result in a near-exponential concentration change in the chamber headspace. Here, we present data from a laboratory experiment and from two field campaigns on the basis of which we evaluate flux calculation approaches based either on linear or exponential regression models. To compare the fit performances of the two models, we used the Akaike Information Criterion with small sample second order bias correction (AICc). For checking the quality of flux data, we used the standard deviation of residuals. The calibration system in the laboratory experiment used during the chamber calibration campaign at Hyytiälä Forestry Field Station in August 2008 has been described by Pumpanen et al. (2004). Five different flux levels on two different soil porosities where tested. Preliminary results show that most concentration-over-time datasets were best described by the exponential model as evaluated by the AICc. It appeared that the flux calculation using the exponential model was better suited to determine the preset fluxes than that using the linear model. In the dataset of the first field campaign (April to October 2007) from Salmisuo (Finland, 62.46˚ N, 30.58˚ E), however, the majority of fluxes was best fitted with a linear regression on all microsite types. Those fluxes which are best fitted exponentially are most probable due to chamber artefacts. They occurred mostly during a drought period in August 2007, which seemed to increase the artificial impact of the chamber. However, these results might be site-specific: In Ust-Pojeg (Russia, 61.56˚ N, 50.13˚ E), where CH4 emissions are supposed to be

  8. Nonlinear model of a distribution transformer appropriate for evaluating the effects of unbalanced loads

    NASA Astrophysics Data System (ADS)

    Toman, Matej; Štumberger, Gorazd; Štumberger, Bojan; Dolinar, Drago

    Power packages for calculation of power system transients are often used when studying and designing electromagnetic power systems. An accurate model of a distribution transformer is needed in order to obtain realistic values from these calculations. This transformer model must be derived in such a way that it is applicable when calculating those operating conditions appearing in practice. Operation conditions where transformers are loaded with nonlinear and unbalanced loads are especially challenging. The purpose of this work is to derive a three-phase transformer model that is appropriate for evaluating the effects of nonlinear and unbalanced loads. A lumped parameter model instead of a finite element (FE) model is considered in order to ensure that the model can be used in power packages for the calculation of power system transients. The transformer model is obtained by coupling electric and magnetic equivalent circuits. The magnetic equivalent circuit contains only three nonlinear reluctances, which represent nonlinear behaviour of the transformer. They are calculated by the inverse Jiles-Atherton (J-A) hysteresis model, while parameters of hysteresis are identified using differential evolution (DE). This considerably improves the accuracy of the derived transformer model. Although the obtained transformer model is simple, the simulation results show good agreement between measured and calculated results.

  9. Neighborhood functions alter unbalanced facilitation on a stress gradient in an alpine treeline simulation

    NASA Astrophysics Data System (ADS)

    Malanson, G. P.; Resler, L. M.

    2014-12-01

    The stress-gradient hypothesis states that individual and species competitive and facilitative effects change in relative importance or intensity along environmental gradients of stress. The importance of the number of facilitators in the neighborhood of a potential beneficiary has not been explored. Evenly distributed and stress-correlated facilitation and the increase in the intensity of facilitation with neighbors as linear, logarithmic, and unimodal functions is simulated for two species such as Pinus albicaulis and Abies lasiocarpa. The mutualism is unbalanced in that the establishment of one species is enhanced by neighbors more than the other. Compared to no facilitation or evenly distributed facilitation, the stress gradient produces more edges in the spatially advancing population, more overall intensity of facilitation, and more individuals further advanced into the area of higher stress; the more enhanced species has increased population relative to the other - to the point where they are equal. Among three neighborhood functions, little difference exists in outcomes between the linear and logarithmic functions, but the unimodal function, which shifts peak facilitation intensity to fewer neighbors, increases the above state variables more than the differences between the even and stress gradient facilitation scenarios. The unbalanced mutualism may be important at treeline ecotones where the spatial pattern becomes central to facilitation.

  10. Crash Frequency Modeling Using Real-Time Environmental and Traffic Data and Unbalanced Panel Data Models

    PubMed Central

    Chen, Feng; Chen, Suren; Ma, Xiaoxiang

    2016-01-01

    Traffic and environmental conditions (e.g., weather conditions), which frequently change with time, have a significant impact on crash occurrence. Traditional crash frequency models with large temporal scales and aggregated variables are not sufficient to capture the time-varying nature of driving environmental factors, causing significant loss of critical information on crash frequency modeling. This paper aims at developing crash frequency models with refined temporal scales for complex driving environments, with such an effort providing more detailed and accurate crash risk information which can allow for more effective and proactive traffic management and law enforcement intervention. Zero-inflated, negative binomial (ZINB) models with site-specific random effects are developed with unbalanced panel data to analyze hourly crash frequency on highway segments. The real-time driving environment information, including traffic, weather and road surface condition data, sourced primarily from the Road Weather Information System, is incorporated into the models along with site-specific road characteristics. The estimation results of unbalanced panel data ZINB models suggest there are a number of factors influencing crash frequency, including time-varying factors (e.g., visibility and hourly traffic volume) and site-varying factors (e.g., speed limit). The study confirms the unique significance of the real-time weather, road surface condition and traffic data to crash frequency modeling. PMID:27322306

  11. Crash Frequency Modeling Using Real-Time Environmental and Traffic Data and Unbalanced Panel Data Models.

    PubMed

    Chen, Feng; Chen, Suren; Ma, Xiaoxiang

    2016-06-18

    Traffic and environmental conditions (e.g., weather conditions), which frequently change with time, have a significant impact on crash occurrence. Traditional crash frequency models with large temporal scales and aggregated variables are not sufficient to capture the time-varying nature of driving environmental factors, causing significant loss of critical information on crash frequency modeling. This paper aims at developing crash frequency models with refined temporal scales for complex driving environments, with such an effort providing more detailed and accurate crash risk information which can allow for more effective and proactive traffic management and law enforcement intervention. Zero-inflated, negative binomial (ZINB) models with site-specific random effects are developed with unbalanced panel data to analyze hourly crash frequency on highway segments. The real-time driving environment information, including traffic, weather and road surface condition data, sourced primarily from the Road Weather Information System, is incorporated into the models along with site-specific road characteristics. The estimation results of unbalanced panel data ZINB models suggest there are a number of factors influencing crash frequency, including time-varying factors (e.g., visibility and hourly traffic volume) and site-varying factors (e.g., speed limit). The study confirms the unique significance of the real-time weather, road surface condition and traffic data to crash frequency modeling.

  12. Object-oriented Bayesian networks for evaluating DIP-STR profiling results from unbalanced DNA mixtures.

    PubMed

    Cereda, G; Biedermann, A; Hall, D; Taroni, F

    2014-01-01

    The genetic characterization of unbalanced mixed stains remains an important area where improvement is imperative. In fact, with current methods for DNA analysis (Polymerase Chain Reaction with the SGM Plus multiplex kit), it is generally not possible to obtain a conventional autosomal DNA profile of the minor contributor if the ratio between the two contributors in a mixture is smaller than 1:10. This is a consequence of the fact that the major contributor's profile 'masks' that of the minor contributor. Besides known remedies to this problem, such as Y-STR analysis, a new compound genetic marker that consists of a Deletion/Insertion Polymorphism (DIP), linked to a Short Tandem Repeat (STR) polymorphism, has recently been developed and proposed elsewhere in literature. The present paper reports on the derivation of an approach for the probabilistic evaluation of DIP-STR profiling results obtained from unbalanced DNA mixtures. The procedure is based on object-oriented Bayesian networks (OOBNs) and uses the likelihood ratio as an expression of the probative value. OOBNs are retained in this paper because they allow one to provide a clear description of the genotypic configuration observed for the mixed stain as well as for the various potential contributors (e.g., victim and suspect). These models also allow one to depict the assumed relevance relationships and perform the necessary probabilistic computations.

  13. How Close Is Close Reading?

    ERIC Educational Resources Information Center

    Saccomano, Doreen

    2014-01-01

    Close Reading is a strategy that can be used when reading challenging text. This strategy requires teachers to provide scaffolding, and create opportunities for think-alouds and rereading of text in order to help students become active readers who focus on finding text-based support for their answers. In addition, teachers must also be aware of…

  14. Effect of control surface mass unbalance on the stability of a closed-loop active control system

    NASA Technical Reports Server (NTRS)

    Nissim, E.

    1989-01-01

    The effects on stability of inertial forces arising from closed-loop activation of mass-unbalanced control surfaces are studied analytically using inertial energy approach, similar to the aerodynamic energy approach used for flutter suppression. The limitations of a single control surface like a leading-edge (LE) control or a trailing-edge (TE) control are demonstrated and compared to the superior combined LE-TE mass unbalanced system. It is shown that a spanwise section for sensor location can be determined which ensures minimum sensitivity to the mode shapes of the aircraft. It is shown that an LE control exhibits compatibility between inertial stabilization and aerodynamic stabilization, and that a TE control lacks such compatibility. The results of the present work should prove valuable, both for the purpose of flutter suppression using mass unbalanced control surfaces, or for the stabilization of structural modes of large space structures by means of inertial forces.

  15. Stable optical spring in the Advanced LIGO detector with unbalanced arms and in the Michelson-Sagnac interferometer

    NASA Astrophysics Data System (ADS)

    Vostrosablin, Nikita; Vyatchanin, Sergey P.

    2014-03-01

    Optical rigidity in the Advanced LIGO gravitational-wave detector, operated on the dark port regime, is unstable. We show that the same interferometer with excluded symmetric mechanical mode but with unbalanced arms allows us to get stable optical spring for the antisymmetric mechanical mode. The arm detuning necessary to get stability is shown to be a small one—it corresponds to small power in the signal port. We show that stable optical spring may be also obtained in the Michelson-Sagnac interferometer with both power and signal recycling mirrors and unbalanced arms.

  16. I/Q reversal phenomena in 4-phase modified Costas Loops. [in-phase and quadrature outputs of unbalanced QPSK

    NASA Technical Reports Server (NTRS)

    Weinberg, A.

    1985-01-01

    A method for predicting the occurrence of I/Q reversals in unbalanced QPSK 4-phase modified Costas Loops is discussed. Potential causes for the reversal of in-phase and quadrature outputs of the unbalanced QPSK demodulator during acquisition and tracking are studied. The design of the unbalance QPSK demodulator and loop characteristics are described. The effect of an anomalous condition during a transient interval or demod/remod operation on data source output is examined. Filtering and hard-limiting effects, and the demodulator loop S-curve stability during tracking are evaluated.

  17. Simultaneous ground-based optical and HF radar observations of the ionospheric footprint of the open/closed field line boundary along the geomagnetic meridian

    NASA Astrophysics Data System (ADS)

    Chen, X.-C.; Lorentzen, D. A.; Moen, J. I.; Oksavik, K.; Baddeley, L. J.

    2015-11-01

    Previous studies have confirmed that the equatorward boundaries of OI 630.0 nm auroral emissions and broad Doppler spectral widths in Super Dual Auroral Radar Network (SuperDARN) data, the so-called spectral width boundary (SWB), are good empirical proxies for the dayside open/closed field line boundary (OCB) in the ionosphere. However, both observational techniques are associated with mapping errors. SuperDARN uses a virtual height model for mapping, but it is not well known how the mapping error responds to a changing background ionosphere or transient reconnection events. Optical instruments, such as the meridian-scanning photometers, have high spatial resolution near zenith, where the mapping error due to the assumed OI 630.0 nm auroral emission height becomes small by comparison. In this work, an adjusted method is introduced to identify the SWB, which does not require temporal smoothing across several scans. The difference in latitude between the SWB, as identified using this method, and the simultaneously observed OI 630.0 nm auroral emission boundary along a common line of sight is compared. Utilizing the OI 630.0 nm boundary as a reference location, we present two case studies observed at different levels of solar activity. In both instances the latitude offset of SWB from the reference location is discussed in relation to the background ionospheric electron density. The compared results indicate that the intake of high-density solar extreme ultraviolet ionized plasma from subauroral latitudes causes a refraction of the HF radar beam path, which results in an overestimation of range mapping. The adjusted method would thus be a useful tool for identifying the OCB under changing ionospheric conditions in the cusp region.

  18. CNCC Craig Campus Geothermal Project: 82-well closed loop GHP well field to provide geothermal energy as a common utilitiy for a new community college campus

    SciTech Connect

    Chevron Energy Solutions; Matt Rush; Scott Shulda

    2011-01-03

    Colorado Northwestern Community College (CNCC) is working collaboratively with recipient vendor Chevron Energy Solutions, an energy services company (ESCO), to develop an innovative GHP project at the new CNCC Campus constructed in 2010/2011 in Craig, Colorado. The purpose of the CNCC Craig Campus Geothermal Program scope was to utilize an energy performance contracting approach to develop a geothermal system with a shared closed-loop field providing geothermal energy to each building's GHP mechanical system. Additional benefits to the project include promoting good jobs and clean energy while reducing operating costs for the college. The project has demonstrated that GHP technology is viable for new construction using the energy performance contracting model. The project also enabled the project team to evaluate several options to give the College a best value proposition for not only the initial design and construction costs but build high performance facilities that will save the College for many years to come. The design involved comparing the economic feasibility of GHP by comparing its cost to that of traditional HVAC systems via energy model, financial life cycle cost analysis of energy savings and capital cost, and finally by evaluating the compatibility of the mechanical design for GHP compared to traditional HVAC design. The project shows that GHP system design can be incorporated into the design of new commercial buildings if the design teams, architect, contractor, and owner coordinate carefully during the early phases of design. The public also benefits because the new CNCC campus is a center of education for the much of Northwestern Colorado, and students in K-12 programs (Science Spree 2010) through the CNCC two-year degree programs are already integrating geothermal and GHP technology. One of the greatest challenges met during this program was coordination of multiple engineering and development stakeholders. The leadership of Principle Investigator

  19. Evolution of the Frequency of Luminous (>=L*V) Close Galaxy Pairs at z < 1.2 in the COSMOS Field

    NASA Astrophysics Data System (ADS)

    Kartaltepe, J. S.; Sanders, D. B.; Scoville, N. Z.; Calzetti, D.; Capak, P.; Koekemoer, A.; Mobasher, B.; Murayama, T.; Salvato, M.; Sasaki, S. S.; Taniguchi, Y.

    2007-09-01

    We measure the fraction of luminous galaxies in pairs at projected separations of 5-20 kpc out to z=1.2 in the Cosmic Evolution Survey (COSMOS) field using ACS images and photometric redshifts derived from an extensive multiwavelength data set. Analysis of a complete sample of 106,188 galaxies more luminous than MV=-19.8 (~L*V) in the redshift range 0.1close pairs. This clearly signifies that galaxy mergers are a very significant and possibly dominant mechanism for galaxy evolution during the epoch of galaxy formation at z=1-3. Based on observations with the NASA/ESA Hubble Space Telescope, obtained at the Space Telescope Science Institute, which is operated by Association of Universities for Research in Astronomy (AURA), Inc., under NASA contract NAS5-26555 also based on data collected at the Subaru Telescope, which is operated by the National Astronomical Observatory of Japan; Kitt Peak National Observatory, Cerro Tololo Inter-American Observatory, and the National Optical Astronomy Observatory, which are operated by AURA, Inc., under cooperative agreement with the National Science Foundation; and the Canada-France-Hawaii Telescope, operated by the National Research Council of Canada, the Centre National de la Recherche Scientifique de France, and the University of Hawaii.

  20. Distortion of magnetic field and magnetic force of a brushless dc motor due to deformed rubber magnet

    NASA Astrophysics Data System (ADS)

    Lee, C. J.; Jang, G. H.

    2008-04-01

    This paper investigates the distortion of magnetic field of a brushless dc (BLDC) motor due to deformed rubber magnet. Global or local deformation of rubber magnet in the BLDC motor is mathematically modeled by using the Fourier series. Distorted magnetic field is calculated by using the finite element method, and unbalanced magnetic force is calculated by using the Maxwell stress tensor. When the rubber magnet is globally or locally deformed, the unbalanced magnetic force has the frequencies with the first harmonic and the harmonics of slot number ±1. However, the harmonic deformation with multiple of common divisor of pole and slot does not generate unbalanced magnetic force due to the rotational symmetry.

  1. Unbalanced and balanced acrocentric rearrangements involving chromosomes other than chromosome 21 at amniocentesis.

    PubMed

    Chen, Chih-Ping; Chern, Schu-Rern; Wu, Pei-Chen; Tsai, Fuu-Jen; Lee, Chen-Chi; Town, Dai-Dyi; Chen, Wen-Lin; Chen, Li-Feng; Lee, Meng-Shan; Pan, Chen-Wen; Wang, Wayseen

    2009-12-01

    To investigate unbalanced and balanced acrocentric rearrangements involving chromosomes other than chromosome 21 at amniocentesis. From January 1987 to September 2009, 31,194 amniocenteses were performed at Mackay Memorial Hospital, Taipei, Taiwan. Two cases with unbalanced acrocentric rearrangements involving chromosomes other than chromosome 21 from two families, and 24 cases with balanced acrocentric rearrangements involving chromosomes other than chromosome 21 from 21 families were diagnosed and investigated. We detected i(13q13q), +13 (one case), rob(13q14q), +13 (one case), rob(13q14q) (16 cases), rob(14q15q) (five cases), rob(13q15q) (one case), rob(15q22q) (one case), and mosaic rob(14q22q) (one case). Of the 25 cases that underwent parental cytogenetic investigation, six arose de novo and 19 were inherited (10 maternal and nine paternal). The 16 families with an inherited Robertsonian translocation included rob(13q14q) (11 families), rob(14q15q) (four families), and rob(15q22q) (one family). Of these 16 families, only two had known parental carrier status prior to the first amniocentesis, while the other 14 were aware of a parental carrier status only after prenatal diagnosis of a fetus with a heterologous Robertsonian translocation. The 18 fetuses with balanced heterologous Robertsonian translocations inherited them from six maternal carriers of rob(13q14q), four paternal carriers of rob(13q14q), four paternal carriers of rob(14q15q), and one maternal carrier of rob(15q22q). Neither UPD14 nor UPD15 was detected in any of the 16 cases tested for UPD. Concerning acrocentric rearrangements involving chromosomes other than chromosome 21, we found a frequency of 0.0064% for unbalanced rearrangements and 0.0769% for balanced rearrangements at amniocentesis in this study. rob(13q14q) was the most common and rob(14q15q) the second most common rearrangement. Of the families with an inherited translocation, 87.5% were aware of parental carrier status only after

  2. Adaptive Phase Synchronization Techniques for Unbalanced and Distorted Three-Phase Voltage System

    NASA Astrophysics Data System (ADS)

    Woinowsky-Krieger, Alexis

    Interfacing and operating AC power electronic systems requires rapid and accurate estimation of the phase angle of the power source, and specifically of the positive sequence of the three-phase utility grid voltage. This is needed to ensure reliable operation of the power control devices and of the resulting power flow. However, the quality of this information is undermined by various distortions and unbalanced conditions of the three-phase grid voltage. Phase estimation and power control can both be performed in real time by a DSP, but a DSP typically has limited computational resources, especially in regards to speed and memory, which motivates the search for computationally efficient algorithms to accomplish these tasks. In contrast to conventional PLL techniques, recent approaches have used adaptive amplitude estimation to enhance the acquisition of the phase information, resulting in faster response and improved performance. This thesis presents a novel technique to estimate the phase of the positive sequence of a three-phase voltage in the presence of frequency variations and unbalanced conditions, referred to as hybrid negative sequence adaptive synchronous amplitude estimation with PLL, or H-NSASAE-PLL. The key feature consists of a feedback structure which embeds a positive sequence PLL and an adaptive synchronous negative sequence estimator to enhance the performance of the PLL. The resulting benefits include faster estimation of the phase of the positive sequence under unbalanced conditions with zero steady state error, simplified tuning of PLL parameters to address a wide range of application requirements, robust performance with respect to distortions and PLL parameters, a structure of minimal dynamical order (fifth) to estimate the main signal parameters of interest, simplified discretization, and reduced computational costs, making the proposed technique suitable for real time execution on a DSP. The H-NSASAE-PLL is developed in the Matlab

  3. Investigating cellular network heterogeneity and modularity in cancer: a network entropy and unbalanced motif approach.

    PubMed

    Cheng, Feixiong; Liu, Chuang; Shen, Bairong; Zhao, Zhongming

    2016-08-26

    Cancer is increasingly recognized as a cellular system phenomenon that is attributed to the accumulation of genetic or epigenetic alterations leading to the perturbation of the molecular network architecture. Elucidation of network properties that can characterize tumor initiation and progression, or pinpoint the molecular targets related to the drug sensitivity or resistance, is therefore of critical importance for providing systems-level insights into tumorigenesis and clinical outcome in the molecularly targeted cancer therapy. In this study, we developed a network-based framework to quantitatively examine cellular network heterogeneity and modularity in cancer. Specifically, we constructed gene co-expressed protein interaction networks derived from large-scale RNA-Seq data across 8 cancer types generated in The Cancer Genome Atlas (TCGA) project. We performed gene network entropy and balanced versus unbalanced motif analysis to investigate cellular network heterogeneity and modularity in tumor versus normal tissues, different stages of progression, and drug resistant versus sensitive cancer cell lines. We found that tumorigenesis could be characterized by a significant increase of gene network entropy in all of the 8 cancer types. The ratio of the balanced motifs in normal tissues is higher than that of tumors, while the ratio of unbalanced motifs in tumors is higher than that of normal tissues in all of the 8 cancer types. Furthermore, we showed that network entropy could be used to characterize tumor progression and anticancer drug responses. For example, we found that kinase inhibitor resistant cancer cell lines had higher entropy compared to that of sensitive cell lines using the integrative analysis of microarray gene expression and drug pharmacological data collected from the Genomics of Drug Sensitivity in Cancer database. In addition, we provided potential network-level evidence that smoking might increase cancer cellular network heterogeneity and

  4. Computing the External Magnetic Scalar Potential due to an Unbalanced Six-Pole Permanent Magnet Motor

    SciTech Connect

    Selvaggi J, Salon S, Kwon O, Chari MVK

    2007-02-12

    The accurate computation of the external magnetic field from a permanent magnet motor is accomplished by first computing its magnetic scalar potential. In order to find a solution which is valid for any arbitrary point external to the motor, a number of proven methods have been employed. Firstly, A finite element model is developed which helps generate magnetic scalar potential values valid for points close to and outside the motor. Secondly, charge simulation is employed which generates an equivalent magnetic charge matrix. Finally, an equivalent multipole expansion is developed through the application of a toroidal harmonic expansion. This expansion yields the harmonic components of the external magnetic scalar potential which can be used to compute the magnetic field at any point outside the motor.

  5. Minority language education in unbalanced bilingual situations: a case for the linguistic interdependence hypothesis.

    PubMed

    Huguet, A; Vila, I; Llurda, E

    2000-05-01

    This paper is placed in the linguistic and sociocultural context of Eastern Aragon, a region of Spain where two contact languages (Spanish and Catalan) coexist in an unbalanced situation favoring Spanish. The research was prompted by the regulation for the teaching of Catalan in that area, by means of the Cooperation Agreement signed by the Spanish Educational Ministry (MEC) and the local autonomous Cultural and Educational Department of the Diputación General de Aragon in November 1986. A comparative analysis is made between Eastern Aragon students' linguistic competence in Catalan and Spanish; a further comparison is established between these students and others living in bilingual Catalonia and in monolingual Aragon. We conclude by pointing out that the Linguistic Interdependence Hypothesis accounts for the results obtained in the study.

  6. New heterogeneous test statistics for the unbalanced fixed-effect nested design.

    PubMed

    Guo, Jiin-Huarng; Billard, L; Luh, Wei-Ming

    2011-05-01

    When the underlying variances are unknown or/and unequal, using the conventional F test is problematic in the two-factor hierarchical data structure. Prompted by the approximate test statistics (Welch and Alexander-Govern methods), the authors develop four new heterogeneous test statistics to test factor A and factor B nested within A for the unbalanced fixed-effect two-stage nested design under variance heterogeneity. The actual significance levels and statistical power of the test statistics were compared in a simulation study. The results show that the proposed procedures maintain better Type I error rate control and have greater statistical power than those obtained by the conventional F test in various conditions. Therefore, the proposed test statistics are recommended in terms of robustness and easy implementation. ©2010 The British Psychological Society.

  7. A capacitive displacement sensing technique for early detection of unbalanced loads in a washing machine.

    PubMed

    Ramasubramanian, Melur K; Tiruthani, Karthik

    2009-01-01

    Horizontal axis washing machines are water and energy efficient and becoming popular in the USA. Unlike a vertical axis washer, these do not have an agitator and depend solely on tumbling for the agitation of laundry during the wash cycle. However, due to the constant shifting of laundry during washing, the load distribution is often unbalanced during the high speed spin cycle. We present a displacement-based sensing method to detect unbalance early while the spin rate (rpm) is well below the resonance frequency so that corrective actions may be taken prior to the high speed spin cycle. Experimental and analytical characterizations of the sensor configuration are presented. Results show that the displacement sensor is more appropriate than an accelerometer for this application and offer the potential for a simple, reliable, low cost detection of unbalance.

  8. Tracking performance of unbalanced QPSK demodulators. II - Biphase Costas loop with active arm filters

    NASA Technical Reports Server (NTRS)

    Simon, M. K.

    1978-01-01

    In a Costas loop study for biphase modulation conducted by Simon and Lindsey (1977), it was demonstrated that considerable improvement in tracking performance could be obtained by employing active arm filters of the integrate-and-dump type as opposed to passive arm filters. An investigation is conducted concerning the possibility to obtain a similar performance improvement for an unbalanced quadriphase-shift-keying (QPSK) modulation. It is found that the biphase Costas loop can be used as an efficient demodulator of QPSK in cases in which the ratio of data rates is of the same order of magnitude as the inverse of the power ratio. These cases involve approximately equal signal energies in the two channels.

  9. The microstructure and properties of titanium dioxide films synthesized by unbalanced magnetron sputtering

    NASA Astrophysics Data System (ADS)

    Leng, Y. X.; Chen, J. Y.; Yang, P.; Sun, H.; Huang, N.

    2007-04-01

    In this work, titanium oxide films were deposited on Ti6Al4V and Si (1 0 0) by DC unbalanced magnetron sputtering method at different oxygen pressure. X-ray diffraction (XRD), microhardness tests, pin-on-disk wear experiments, surface contact angle tests and platelet adhesion investigation were conducted to evaluate the properties of the films. The corrosion behavior of titanium dioxide films was characterized by potentiodynamic polarization. The results showed that titanium oxide films deposited by unbalance magnetron sputtering were compact and could obviously enhance microhardness, wear resistance of titanium alloy substrate. Potentiodynamic polarization curves showed that Ti-6Al-4V deposited with titanium dioxide films had lower dissolution currents than that of the uncoated one. The results of in vitro hemocompatibility analyses indicated that the blood compatibility of the titanium dioxide films with bandgap 3.2 eV have better blood compatibility.

  10. Vortex array laser beam generation from a Dove prism-embedded unbalanced Mach-Zehnder interferometer.

    PubMed

    Chu, Shu-Chun; Yang, Chao-Shun; Otsuka, Kenju

    2008-11-24

    This paper proposes a new scheme for generating vortex laser beams from a laser. The proposed system consists of a Dove prism embedded in an unbalanced Mach-Zehnder interferometer configuration. This configuration allows controlled construction of p x p vortex array beams from Ince-Gaussian modes, IG(e) (p,p) modes. An incident IG(e)(p,p) laser beam of variety order p can easily be generated from an end-pumped solid-state laser system with an off-axis pumping mechanism. This study simulates this type of vortex array laser beam generation, analytically derives the vortex positions of the resulting vortex array laser beams, and discusses beam propagation effects. The resulting vortex array laser beam can be applied to optical tweezers and atom traps in the form of two-dimensional arrays, or used to study the transfer of angular momentum to micro particles or atoms (Bose-Einstein condensate).

  11. Influence of goal-directed therapy with balanced crystalloid-colloid or unbalanced crystalloid solution on base excess.

    PubMed

    Krebbel, Holger; Feldheiser, Aarne; Müller, Olga; Boemke, Willehad; Sander, Michael; Perka, Carsten; Wernecke, Klaus-Dieter; Spies, Claudia

    2014-04-01

    To investigate changes in standard base excess (SBE) when administering two different infusion regimens for elective hip replacement within a goal-directed haemodynamic algorithm. This prospective, double-blind, randomized, controlled study enrolled patients scheduled for primary hip replacement surgery, who were randomized to receive either an unbalanced crystalloid (chloride: 155.5 mmol/l) or a 1 : 1 mixture of a balanced crystalloid and a balanced colloid (6% w/v hydroxyethyl starch 130/0.42; chloride: 98 and 112 mmol/l, respectively). Fluid management was goal-directed to optimize stroke volume using oesophageal Doppler. A total of 40 patients (19 female/21 male) participated in the study. After surgery, median (25-75% percentiles) SBE was significantly lower in the unbalanced group compared with the balanced group: -2.0 mmol/l (-3.1 to -1.1) versus -0.4 mmol/l (-1.2 to 0.7), respectively. This difference was mainly due to greater plasma chloride concentrations in the unbalanced group. The amount of study medication required to reach haemodynamic stability (median 1200 ml) did not differ between the two groups. SBE decreased in the unbalanced group without influence on fluid requirements and haemodynamic stability.

  12. Assumption or Fact? Line-to-Neutral Voltage Expression in an Unbalanced 3-Phase Circuit during Inverter Switching

    ERIC Educational Resources Information Center

    Masrur, M. A.

    2009-01-01

    This paper discusses the situation in a 3-phase motor or any other 3-phase system operating under unbalanced operating conditions caused by an open fault in an inverter switch. A dc voltage source is assumed as the input to the inverter, and under faulty conditions of the inverter switch, the actual voltage applied between the line to neutral…

  13. Assembly of an unbalanced charged polyampholyte onto Nafion® to produce high-performance composite membranes.

    PubMed

    Li, Shenghai; Zhang, Suobo; Zhang, Qifeng; Qin, Guorui

    2012-12-28

    A novel SPES-NH(2)-GA-Nafion® composite membrane with higher proton conductivity and lower methanol permeability was fabricated by covalent crosslinking layer-by-layer self-assembly of an unbalanced charged polyampholyte (SPES-NH(2)) and glutaraldehyde (GA) with controllable free sulfonic acid content.

  14. Assumption or Fact? Line-to-Neutral Voltage Expression in an Unbalanced 3-Phase Circuit during Inverter Switching

    ERIC Educational Resources Information Center

    Masrur, M. A.

    2009-01-01

    This paper discusses the situation in a 3-phase motor or any other 3-phase system operating under unbalanced operating conditions caused by an open fault in an inverter switch. A dc voltage source is assumed as the input to the inverter, and under faulty conditions of the inverter switch, the actual voltage applied between the line to neutral…

  15. Disruption of genes in the retinoid cascade may explain the microscopic neuroblastoma in a fetus with de novo unbalanced translocation

    SciTech Connect

    Goodman, A.B.

    1995-03-13

    The microscopic neuroblastoma in a fetus with de novo unbalanced translocation (3;10)(q21;q26) may be explained as the disruption of genes in the retinoid cascade, rather than simply a two-hit hypothesis for the development of tumor cells. 5 refs.

  16. Unbalanced 2 x 2 factorial designs and the interaction effect: a troublesome combination.

    PubMed

    Landsheer, Johannes A; van den Wittenboer, Godfried

    2015-01-01

    In this power study, ANOVAs of unbalanced and balanced 2 x 2 datasets are compared (N = 120). Datasets are created under the assumption that H1 of the effects is true. The effects are constructed in two ways, assuming: 1. contributions to the effects solely in the treatment groups; 2. contrasting contributions in treatment and control groups. The main question is whether the two ANOVA correction methods for imbalance (applying Sums of Squares Type II or III; SS II or SS III) offer satisfactory power in the presence of an interaction. Overall, SS II showed higher power, but results varied strongly. When compared to a balanced dataset, for some unbalanced datasets the rejection rate of H0 of main effects was undesirably higher. SS III showed consistently somewhat lower power. When the effects were constructed with equal contributions from control and treatment groups, the interaction could be re-estimated satisfactorily. When an interaction was present, SS III led consistently to somewhat lower rejection rates of H0 of main effects, compared to the rejection rates found in equivalent balanced datasets, while SS II produced strongly varying results. In data constructed with only effects in the treatment groups and no effects in the control groups, the H0 of moderate and strong interaction effects was often not rejected and SS II seemed applicable. Even then, SS III provided slightly better results when a true interaction was present. ANOVA allowed not always for a satisfactory re-estimation of the unique interaction effect. Yet, SS II worked better only when an interaction effect could be excluded, whereas SS III results were just marginally worse in that case. Overall, SS III provided consistently 1 to 5% lower rejection rates of H0 in comparison with analyses of balanced datasets, while results of SS II varied too widely for general application.

  17. Comparison of Heliospheric Current Sheet Structure Obtained from Potential Magnetic Field Computations and from Observed Polarization Coronal Brightness,

    DTIC Science & Technology

    1983-02-01

    the current sheet computed with the potential field approximation appears to be distorted by a large photospheric region of unbalanced magnetic flux...1982) attributed the northward bulge in the PF current sheet to an unusually large photospheric region of unbalanced "towari" polarity that was observed...currents would not be very good observed at the earth iSvalgaard and Wilcox. 19751. Occa- for the strong localized fields of an active region , but for the

  18. Sensitive DIP-STR markers for the analysis of unbalanced mixtures from "touch" DNA samples.

    PubMed

    Oldoni, Fabio; Castella, Vincent; Grosjean, Frederic; Hall, Diana

    2017-05-01

    Casework samples collected for forensic DNA analysis can produce genomic mixtures in which the DNA of the alleged offender is masked by high quantities of DNA coming from the victim. DIP-STRs are novel genetic markers specifically developed to enable the target analysis of a DNA of interest in the presence of exceeding quantities of a second DNA (up to 1000-fold). The genotyping system, which is based on allele-specific amplifications of haplotypes formed by a deletion/insertion polymorphism (DIP) and a short tandem repeat (STR), combines the capacity of targeting the DNA of an individual with a strong identification power. Finally, DIP-STRs are autosomal markers therefore they can be applied to any combination of major and minor DNA. In this study we aimed to assess the ability of DIP-STRs to detect the minor contributor on challenging "touch" DNA samples simulated with representative crime-associated substrates and to compare their performance to commonly used male-specific markers (Y-STRs). As part of a comprehensive study on the relative DNA contribution of two persons handling the same object, we selected 71 unbalanced contact traces of which 14 comprised a male minor DNA contributor mixed to a female major DNA contributor. Using a set of six DIP-STRs, one to four markers were found to be informative for the minor DNA detection across traces. When compared to Y-STRs (14 traces), the DIP-STRs showed similar sensitivity in detecting the minor DNA across substrate materials with a similar occurrence of allele drop-out. Conversely, because of the sex combination of the two users of the object, 57 remaining traces could only be investigated by DIP-STRs. Of these, 30 minor DNA contributors could be detected by all informative markers while 12 traces showed events of allele drop-out. Finally, 15 traces showed no amplification of the minor DNA. These last 15 samples were mostly characterized by a combination of short handling time of the object, low DNA recovery and

  19. Mitral and tricuspid valve repair and growth in unbalanced atrial ventricular canal defects.

    PubMed

    Foker, John E; Berry, James M; Harvey, Brian A; Pyles, Lee A

    2012-04-01

    Congenital mitral and tricuspid valve abnormalities in unbalanced atrioventricular canal defects are complex. We designed procedures to both repair and induce growth of hypoplastic atrioventricular valves and ventricles to achieve 2-ventricle repairs. Midterm data were assessed for reliability of catch-up growth, resulting quality of atrioventricular valves, and adequacy of 2-ventricle repairs. The 24 consecutive infants (14 female and 10 male) with unbalanced atrioventricular canal defects had significant hypoplasia of 1 atrioventricular valve and/or ventricle (an echocardiography-derived z value of ≤-3.0 standard errors of the mean below expected). Operative approaches included the following: (1) Staged repair was performed, with complete valve repair, partial closure of the atrial septal, and ventricular septal defects, and (usually) pulmonary artery banding. After adequate growth, repair was completed. A vestigial mitral valve (4-7 mm) in 3 patients led to partitioning the large tricuspid valve, creating a second mitral valve. (2) Repair with a shift in atrioventricular valve partitioning was performed to increase hypoplastic atrioventricular valve size. (3) Repair with snared atrial septal defects and ventricular septal defect was performed to allow intracardiac shunting. The hypoplastic atrioventricular valves and hypoplastic ventricles were reassessed on local follow-up (5-15 years). The initial z scores were -2.8 to -7.4 for hypoplastic atrioventricular valves and -1.0 to -7.5 for hypoplastic ventricles. Follow-up z scores were -0.6 to -2.7 for hypoplastic atrioventricular valves and -2.0 to +1.8 for hypoplastic ventricles. Another 11 patients were also judged to be within normal limits. Three reoperations were for mitral valve regurgitation, and 1 reoperation was for mitral valve replacement. One patient died of central nervous system bleed just before extracorporeal membrane oxygenation weaning, and 2 patients died of late potassium overdose, for an 88

  20. Molecular analysis of an unbalanced deletion of the short arm of chromosome 5 that produces no phenotype.

    PubMed Central

    Overhauser, J; Golbus, M S; Schonberg, S A; Wasmuth, J J

    1986-01-01

    A family has been identified in which an interstitial, apparently unbalanced deletion of the short arm of chromosome 5 could be traced through six individuals in 3 generations. Remarkably, all of the individuals with the deletion are completely asymptomatic and show no physical or mental abnormalities. The deletion was confirmed at the molecular level by identifying DNA probes that mapped within the deleted portion of chromosome 5. Through the use of somatic cell hybrids and quantitative Southern blots, we demonstrated that these individuals do indeed have an unbalanced deletion and are haploid for several million base pairs of DNA in 5p14 without showing any discernable phenotype. Images Fig. 2 Fig. 4 Fig. 5 PMID:3752077

  1. Partial trisomy of 11q23.3-q25 inherited from a maternal low-level mosaic unbalanced translocation.

    PubMed

    Choi, Jungyoon; Lee, Hojung; Lee, Cha Gon

    2015-08-01

    Partial trisomy of 11q is characterized by pre/postnatal growth retardation, microcephaly, dysmorphic craniofacial features, cognitive disability, abnormal muscle tone, inguinal hernia, and possible congenital heart defects. Here, we describe a 17-year-old male with a 17.77 Mb-sized [arr 11q23.3-q25 (116,667,559 -134,434,130) ×3] partial trisomy resulting from the unbalanced translocation between chromosomes 11 and 22. The terminal translocation was detected using oligonucleotide array comparative genomic hybridization (CGH) with fluorescence in situ hybridization (FISH) confirmation. The partial trisomy was inherited from his mother who had the low-level (22.7%) mosaic unbalanced translocation and a normal phenotype. The patient showed most of the common features of partial trisomy 11q syndrome, with additional findings, including mesenteric fibromatosis.

  2. Three-phase Unbalanced Interval Power Flow Calculation of Low-voltage Distribution Network with Distributed PV Power Generation

    NASA Astrophysics Data System (ADS)

    Yuan, Yan; Shunjiang, Lin; Yuan, Lu

    2017-05-01

    Low-voltage distribution network is a three-phase unbalanced system due to the integration of single-phase loads and single-phase distributed PV arrays. In this paper, three-phase unbalanced interval power flow calculation model of three-phase four-wire low voltage distribution network with distributed PV power generation is established. In the model, intensity of illumination and battery temperature which influence the power output of distributed PV power generation is described as intervals. Then, through the affine interval algorithm, the interval power flow problem is transformed into a deterministic power flow problem and two linear optimization problems. By solving the above problems, the interval power flow solution can be obtained. Finally, the proposed algorithm is applied to an actual 22-bus low-voltage distribution network, and the solution of the affine interval algorithm is compared to the solution of the Monte Carlo sampling method, which verifies the correctness and effectiveness of the proposed algorithm.

  3. DNA fragmentation is higher in spermatozoa with chromosomally unbalanced content in men with a structural chromosomal rearrangement.

    PubMed

    Perrin, A; Nguyen, M H; Bujan, L; Vialard, F; Amice, V; Guéganic, N; Douet-Guilbert, N; De Braekeleer, M; Morel, F

    2013-07-01

    It has been previously shown that men with chromosomal structural abnormality had a higher rate of sperm DNA fragmentation. We studied 11 male carriers of a chromosomal structural abnormality (seven with a balanced reciprocal translocation, three with a Robertsonian translocation, one with a pericentric inversion) to determine whether spermatozoa with unbalanced chromosomes were more likely to have fragmented DNA. A sequential method combining analysis of DNA fragmentation using the TUNEL assay followed by analysis of meiotic segregation by fluorescent in situ hybridization was performed on the same spermatozoa. A statistically significant higher number of spermatozoa with unbalanced chromosomal content were found to have fragmented DNA for each man. The rate of spermatozoa with DNA fragmentation was higher than the rate of those without fragmented DNA in particular modes of segregation. Our findings provide a better understanding of the mechanisms involved in male infertility ascribable to chromosomal structural abnormality. © 2013 American Society of Andrology and European Academy of Andrology.

  4. Effects of magnetic flux density and substrate bias voltage on Ni films prepared on a flexible substrate material using unbalanced magnetron sputtering assisted by inductively coupled plasma

    SciTech Connect

    Koda, Tatsunori; Toyota, Hiroshi

    2014-03-15

    The authors fabricated Ni films on a flexible substrate material using unbalanced magnetron sputtering assisted by inductively coupled plasma. The effects of magnetic flux density B{sub C} and substrate DC bias voltage V{sub S} on the Ni film structures were investigated. For V{sub S} = −40 V, the average surface grain size D{sub G} measured by atomic force microscopy for B{sub C} = 0, 3, and 5 mT was 88.2, 95.4, and 104.4 nm, respectively. In addition, D{sub G} increased with V{sub S}. From x-ray diffraction measurements, the (111) and (200) peaks were clearly visible for the fabricated Ni films. The ratio of the integrated intensities of I(111)/I(200) increased with V{sub S}. For V{sub S} = −40 V and B{sub C} = 3 mT, a film resistivity ρ of 8.96 × 10{sup −6} Ω cm was observed, which is close to the Ni bulk value of 6.84 × 10{sup −6} Ω cm. From these results, the authors determined that the structure of the fabricated Ni films on the flexible substrate material was affected by the values of B{sub C} and V{sub S}.

  5. Characteristics of electric-field-induced polarization rotation in <001>-poled Pb(Mg1/3Nb2/3)O3-PbTiO3 single crystals close to the morphotropic phase boundary

    NASA Astrophysics Data System (ADS)

    Peräntie, J.; Hagberg, J.; Uusimäki, A.; Tian, J.; Han, P.

    2012-08-01

    The special characteristics of polarization rotation and accompanying electric-field-induced ferroelectric-ferroelectric phase transitions in <001>-poled Pb(Mg1/3Nb2/3)1-xTixO3 (x = 27.4, 28.8, and 30.7 mol. %) single crystals close to the morphotropic phase boundary region were studied by means of dielectric and thermal measurements as a function of a unipolar electric field at various temperatures. Discontinuous first-order-type phase transition behavior was evidenced by distinct and sharp changes in polarization and thermal responses with accompanying hysteresis as a function of the electric field. All compositions of crystals showed either one or two reversible discontinuities along the polarization rotation paths, which can be understood by electric-field-induced phase transition sequences to the tetragonal phase through different monoclinic phases previously observed along the polarization rotation path. Together with increasing polarization, a field-induced reversible decrease in temperature was observed with increasing electric field, indicating increased dipolar entropy during the electric-field-induced phase transitions. Constructed electric field-temperature phase diagrams based on the polarization and thermal data suggest that the complex polarization rotation path extends to a wider composition range than previously observed. The measured thermal response showed that a transition from the monoclinic to the tetragonal phase produced a greater thermal change in comparison with a transition within two monoclinic phases.

  6. Unbalanced synaptic inputs underlying multi-peaked frequency selectivity in rat auditory cortex.

    PubMed

    Zhou, Chang; Tao, Can; Zhang, Guangwei; Yan, Sumei; Wang, Lijuan; Zhou, Yi; Xiong, Ying

    2017-04-01

    By measuring the frequency selectivity at different intensities in the primary auditory cortex of adult rats, we found that a small group of cortical neurons can exhibit relatively weak but robust selectivity at multiple frequencies that are different from the most preferred frequency. Both in vivo multi-unit recordings (26/93 recordings) and single-unit recordings (16/137 neurons) confirmed that the preferred frequencies are periodic and have an averaged bandwidth (BW) of 0.3-0.4 octaves, which leads to multi-peaked frequency selectivity. Interestingly, the averaged bandwidth of the ripple in the frequency response tuning curve was invariant with the sound intensity. An investigation of the synaptic currents in vivo also revealed similar multi-peaked frequency selectivity for both excitation and inhibition. While the excitatory and inhibitory inputs were relatively balanced for most frequencies, the ratio between excitation and inhibition at the peak and valley of each ripple was highly unbalanced. Since this multi-peaked frequency selectivity can be observed at the synaptic, single-cell, and population levels, our results reveal a potential mechanism underlying the multi-peaked pattern of frequency selectivity in the primary auditory cortex. © 2017 Federation of European Neuroscience Societies and John Wiley & Sons Ltd.

  7. Analysis of variance with unbalanced data: an update for ecology & evolution.

    PubMed

    Hector, Andy; von Felten, Stefanie; Schmid, Bernhard

    2010-03-01

    1. Factorial analysis of variance (anova) with unbalanced (non-orthogonal) data is a commonplace but controversial and poorly understood topic in applied statistics. 2. We explain that anova calculates the sum of squares for each term in the model formula sequentially (type I sums of squares) and show how anova tables of adjusted sums of squares are composite tables assembled from multiple sequential analyses. A different anova is performed for each explanatory variable or interaction so that each term is placed last in the model formula in turn and adjusted for the others. 3. The sum of squares for each term in the analysis can be calculated after adjusting only for the main effects of other explanatory variables (type II sums of squares) or, controversially, for both main effects and interactions (type III sums of squares). 4. We summarize the main recent developments and emphasize the shift away from the search for the 'right'anova table in favour of presenting one or more models that best suit the objectives of the analysis.

  8. Unbalanced omega-6/omega-3 ratio in red meat products in China

    PubMed Central

    Yu, Ming; Gao, Qianqian; Wang, Yan; Zhang, Wei; Li, Lin; Wang, Ying; Dai, Yifan

    2013-01-01

    Dietary meats play a crucial role in human health. The objective of this survey was to determine the fatty acid content and omega-6/omega-3 polyunsaturated fatty acids (n-6/n-3 PUFA) ratio of fresh red meat (beef and pork) from four cities (Shanghai, Nanjing, Yinchuan and Hohhot) in China. The results showed that the n-6/n-3 PUFA ratio from all the samples ranged from 6 to 23. The total n-6 PUFA concentrations ranged from 290.54 mg/100 g in beef from Nanjing to 1601.48 mg/100 g in pork from Hohhot, whereas the total concentrations of n-3 PUFA ranged from 46.34 mg/100 g in beef from Nanjing to 96.03 mg/100 g in pork from Nanjing. The results indicated that the n-6/n-3 ratio in the red meat from all four regions is unbalanced and is much higher than that (< 5:1) recommended by the WHO/FAO. The total amount of n-3 PUFA was far lower than the required daily dose. Therefore, potential solutions to increase the n-3 PUFA content in meat products or to provide alternative source of n-3 PUFA should be explored. PMID:24086169

  9. Generation of new compounds through unbalanced transcription of landomycin A cluster.

    PubMed

    Myronovskyi, Maksym; Brötz, Elke; Rosenkränzer, Birgit; Manderscheid, Niko; Tokovenko, Bogdan; Rebets, Yuriy; Luzhetskyy, Andriy

    2016-11-01

    The biosynthetically well-studied landomycin A cluster has been used to demonstrate the unbalancing of gene transcription as an efficient method for the generation of new compounds. Landomycin A structural genes were decoupled from the native regulators LanI and LanK and placed under the control of a single synthetic promoter and expressed in a heterologous host Streptomyces albus J1074. In contrast to their native quantitative and temporal regulation, these genes were transcribed as a single polycistronic mRNA leading to the production of four novel and two known compounds. No glycosylated landomycins were detected though the entire biosynthetic cluster was transcribed, showing the crucial role of the balanced gene expression for the production of landomycin A. Two new compounds, fridamycin F and G, isolated in this study were shown to originate from the interplay between the expressed biosynthetic pathway and metabolic network of the heterologous host. Structure activity studies of the isolated compounds as well as results of transcriptome sequencing are discussed in this article.

  10. Effect of noisy phase reference on coherent detection of unbalanced QPSK signals

    NASA Technical Reports Server (NTRS)

    Osborne, H. C.

    1978-01-01

    A phase error in the reference signal used in coherent detection of PSK signals causes a degradation in performance; this effect on bit error probability has been much discussed in the literature for BPSK and balanced QPSK systems. For unbalanced QPSK (UQPSK) systems, where the power and data rates in the two channels are unequal, and where the channel data symbols might also be different, the problem of computing the error probability is more complex, and only approximate solutions have been previously given. In this paper, exact expressions are derived for the conditional probability of error for the I and Q channels as a function of the channel power and data rate ratio. This is done for all combinations of Manchester and NRZ signalling schemes, and it is shown that in some cases the low data rate channel can be more seriously affected by a phase offset. Numerical results are also given for the average probability of error, assuming a biphase Costas loop is used for carrier synchronization.

  11. Nonlinear dynamic behaviors of permanent magnet synchronous motors in electric vehicles caused by unbalanced magnetic pull

    NASA Astrophysics Data System (ADS)

    Xiang, Changle; Liu, Feng; Liu, Hui; Han, Lijin; Zhang, Xun

    2016-06-01

    Unbalanced magnetic pull (UMP) plays a key role in nonlinear dynamic behaviors of permanent magnet synchronous motors (PMSM) in electric vehicles. Based on Jeffcott rotor model, the stiffness characteristics of the rotor system of the PMSM are analyzed and the nonlinear dynamic behaviors influenced by UMP are investigated. In free vibration study, eigenvalue-based stability analysis for multiple equilibrium points is performed which offers an insight in system stiffness. Amplitude modulation effects are discovered of which the mechanism is explained and the period of modulating signal is carried out by phase analysis and averaging method. The analysis indicates that the effects are caused by the interaction of the initial phases of forward and backward whirling motions. In forced vibration study, considering dynamic eccentricity, frequency characteristics revealing softening type are obtained by harmonic balance method, and the stability of periodic solution is investigated by Routh-Hurwitz criterion. The frequency characteristics analysis indicates that the response amplitude is limited in the range between the amplitudes of the two kinds of equilibrium points. In the vicinity of the continuum of equilibrium points, the system hardly provides resistance to bending, and hence external disturbances easily cause loss of stability. It is useful for the design of the PMSM with high stability and low vibration and acoustic noise.

  12. Unbalanced oil filled sphere as rolling pendulum on a flat surface to damp horizontal structural vibrations

    NASA Astrophysics Data System (ADS)

    Bransch, Martin

    2016-04-01

    The passive damping of horizontal structural vibrations by means of an unbalanced oil filled sphere as a tuned mass damper (TMD) is examined. Due to the unbalance contained in the TMD, a pendulum-like motion is produced. The TMD lies unconstrained on the structure. As a result, forces are only transferred through the static friction between the TMD and the structure. The TMD is filled with oil to enable energy dissipation. This paper investigates the mechanical system of the proposed TMD and calculation methods for its tuning. Furthermore, experimental results of the TMD are presented. To determine the advantages and disadvantages of the proposed TMD, it will be compared to other passive tuned mass dampers. The advantages of the presented TMD are its robust design, simple mounting/demounting onto the main system and its adjustability after mounting. The oil filling makes the damper construction simple, as an additional container for the oil is no longer needed. Furthermore, the energy dissipating effect of breaking waves is used when the oil level inside the TMD is shallow. The disadvantages of the presented TMD when compared to a conventional tuned mass damper (linear spring-mass-damper-system) are its slightly lower performance and its complex tuning.

  13. Pointing and Scanning Control of Optical Instruments using Rotating Unbalanced Masses

    NASA Technical Reports Server (NTRS)

    Bishop, Carlee A.; Hung, John Y.; Polites, Michael E.; Alhorn, Dean C.

    1996-01-01

    Correct pointing direction and scanning motions are essential in the operation of many flight payloads, such as balloon-borne telescopes and space-based X- ray and gamma-ray telescopes. Rotating unbalanced mass (RUM) devices have been recently proposed, implemented and successfully tested to produce a variety of scanning motions. Linear scans, raster scans, and circular scans have been successfully generated on a gimbaled payload using pairs of RUM devices. Theoretical analysis, computer simulations, and experiments have also been used to study the feasibility of using RUM devices to control instrument pointing direction, in addition to generating scanning motion. Dynamic modeling of a gimbaled payload equipped with a pair of RUM devices has been studied, and preliminary testing indicates that the pointing control is indeed feasible. However, there is also great potential for significant performance improvements through more advanced control system analysis, modeling and design. In this paper, modeling and control methods are described to achieve simultaneous scanning and pointing control of a gimbaled payload using rotating unbalance mass (RUM) devices. The model development work builds upon the results of Polites et al. and also some modeling approaches from robotics research. Results of some preliminary experiments are discussed and some nonlinear control methods will be proposed.

  14. Rotating Unbalanced-Mass devices for scanning: Results from the proof-of-concept test

    NASA Technical Reports Server (NTRS)

    Alhorn, Dean C.; Polites, Michael E.

    1994-01-01

    Rotating unbalanced-mass (RUM) devices are a new way to scan space-based, balloon-borne, and ground-based gimbaled payloads, like x-ray and gamma-ray telescopes. They can also be used to scan free-flying spacecraft. Circular scans, linear scans, and raster scans can be generated. A pair of RUM devices generates the basic scan motion and an auxiliary control system using torque motors, control moment gyros, or reaction wheels keeps the scan centered on the target and produces some complementary motion for raster scanning. Previous analyses and simulation results show that this approach offers significant power savings compared to scanning only with the auxiliary control system, especially with large payloads and high scan frequencies. However, these claims have never been proven until now. This paper describes a laboratory experiment which tests the concept of scanning a gimbaled payload with RUM devices. The test results are compared with those from a computer simulation model of the experiment and the differences are discussed.

  15. Surface treatment effect on Si (111) substrate for carbon deposition using DC unbalanced magnetron sputtering

    NASA Astrophysics Data System (ADS)

    Aji, A. S.; Sahdan, M. F.; Hendra, I. B.; Dinari, P.; Darma, Y.

    2015-04-01

    In this work, we studied the effect of HF treatment in silicon (111) substrate surface for depositing thin layer carbon. We performed the deposition of carbon by using DC Unbalanced Magnetron Sputtering with carbon pallet (5% Fe) as target. From SEM characterization results it can be concluded that the carbon layer on HF treated substrate is more uniform than on substrate without treated. Carbon deposition rate is higher as confirmed by AFM results if the silicon substrate is treated by HF solution. EDAX characterization results tell that silicon (111) substrate with HF treatment have more carbon fraction than substrate without treatment. These results confirmed that HF treatment on silicon Si (111) substrates could enhance the carbon deposition by using DC sputtering. Afterward, the carbon atomic arrangement on silicon (111) surface is studied by performing thermal annealing process to 900 °C. From Raman spectroscopy results, thin film carbon is not changing until 600 °C thermal budged. But, when temperature increase to 900 °C, thin film carbon is starting to diffuse to silicon (111) substrates.

  16. Vibration analysis of rolling element bearings with various defects under the action of an unbalanced force

    NASA Astrophysics Data System (ADS)

    Kıral, Zeki; Karagülle, Hira

    2006-11-01

    In this paper, a method based on the finite element vibration analysis is presented for defect detection in rolling element bearings with single or multiple defects on different components of the bearing structure using the time and frequency domain parameters. A dynamic loading model is proposed in order to create the nodal excitation functions used in the finite element vibration analysis as external loading. A computer code written in Visual Basic programming language with a graphical user interface is developed to create the nodal excitations for different cases including the outer ring, inner ring or rolling element defects. Forced vibration analysis of a bearing structure is performed using the commercial finite element package I-DEAS under the action of an unbalanced force transferred to the structure via a ball bearing. Time and frequency domain parameters such as rms, crest factor, kurtosis and band energy ratio for the frequency spectrum of the enveloped signals are used to analyse the effect of the defect location and the number of defects on the time and frequency domain parameters. The role of the receiving point for vibration measurements is also investigated. The vibration data for various defect cases including the housing structure effect can be obtained using the finite element vibration analysis in order to develop an optimum monitoring method in condition monitoring studies.

  17. Carbon film deposition on SnO2/Si(111) using DC unbalanced magnetron sputtering

    NASA Astrophysics Data System (ADS)

    Aji, A. S.; Darma, Y.

    2013-09-01

    In this paper, carbon deposition on SnO2 layer using DC unbalanced magnetron-sputtering technique at low temperature has been systematically studied. Sputtering process were carried out at pressure of 4.6×10-2 Torr by keeping the substrate temperature at 300 °C. SnO2 were growth on silicon (111) substrate using thermal evaporation and continuing with dry oxidation of Sn at 225 °C. Thermal evaporation for high purity Sn was conducted by maintain the current source as high as 40 ampere. The quality of SnO2 on Si(111) and the characteristic of carbon thin film on SnO2 were analized by mean XRD, FTIR and Raman spectra. XRD analysis shows that SnO2 film is growth uniformly on Si(111). FTIR and Raman spectra confirm the formation of thin film carbon on SnO2. Additionally, thermal annealing for some sample series have been performed to study their structural stability. The change of atomic structure due to thermal annealing were analized by Raman and XRD spectra.

  18. Severe encephalopathy associated to pyruvate dehydrogenase mutations and unbalanced coenzyme Q10 content

    PubMed Central

    Asencio, Claudio; Rodríguez-Hernandez, María A; Briones, Paz; Montoya, Julio; Cortés, Ana; Emperador, Sonia; Gavilán, Angela; Ruiz-Pesini, Eduardo; Yubero, Dèlia; Montero, Raquel; Pineda, Mercedes; O'Callaghan, María M; Alcázar-Fabra, María; Salviati, Leonardo; Artuch, Rafael; Navas, Plácido

    2016-01-01

    Coenzyme Q10 (CoQ10) deficiency is associated to a variety of clinical phenotypes including neuromuscular and nephrotic disorders. We report two unrelated boys presenting encephalopathy, ataxia, and lactic acidosis, who died with necrotic lesions in different areas of brain. Levels of CoQ10 and complex II+III activity were increased in both skeletal muscle and fibroblasts, but it was a consequence of higher mitochondria mass measured as citrate synthase. In fibroblasts, oxygen consumption was also increased, whereas steady state ATP levels were decreased. Antioxidant enzymes such as NQO1 and MnSOD and mitochondrial marker VDAC were overexpressed. Mitochondria recycling markers Fis1 and mitofusin, and mtDNA regulatory Tfam were reduced. Exome sequencing showed mutations in PDHA1 in the first patient and in PDHB in the second. These genes encode subunits of pyruvate dehydrogenase complex (PDH) that could explain the compensatory increase of CoQ10 and a defect of mitochondrial homeostasis. These two cases describe, for the first time, a mitochondrial disease caused by PDH defects associated with unbalanced of both CoQ10 content and mitochondria homeostasis, which severely affects the brain. Both CoQ10 and mitochondria homeostasis appears as new markers for PDH associated mitochondrial disorders. PMID:26014431

  19. Severe encephalopathy associated to pyruvate dehydrogenase mutations and unbalanced coenzyme Q10 content.

    PubMed

    Asencio, Claudio; Rodríguez-Hernandez, María A; Briones, Paz; Montoya, Julio; Cortés, Ana; Emperador, Sonia; Gavilán, Angela; Ruiz-Pesini, Eduardo; Yubero, Dèlia; Montero, Raquel; Pineda, Mercedes; O'Callaghan, María M; Alcázar-Fabra, María; Salviati, Leonardo; Artuch, Rafael; Navas, Plácido

    2016-03-01

    Coenzyme Q10 (CoQ10) deficiency is associated to a variety of clinical phenotypes including neuromuscular and nephrotic disorders. We report two unrelated boys presenting encephalopathy, ataxia, and lactic acidosis, who died with necrotic lesions in different areas of brain. Levels of CoQ10 and complex II+III activity were increased in both skeletal muscle and fibroblasts, but it was a consequence of higher mitochondria mass measured as citrate synthase. In fibroblasts, oxygen consumption was also increased, whereas steady state ATP levels were decreased. Antioxidant enzymes such as NQO1 and MnSOD and mitochondrial marker VDAC were overexpressed. Mitochondria recycling markers Fis1 and mitofusin, and mtDNA regulatory Tfam were reduced. Exome sequencing showed mutations in PDHA1 in the first patient and in PDHB in the second. These genes encode subunits of pyruvate dehydrogenase complex (PDH) that could explain the compensatory increase of CoQ10 and a defect of mitochondrial homeostasis. These two cases describe, for the first time, a mitochondrial disease caused by PDH defects associated with unbalanced of both CoQ10 content and mitochondria homeostasis, which severely affects the brain. Both CoQ10 and mitochondria homeostasis appears as new markers for PDH associated mitochondrial disorders.

  20. Study on nitrogenated amorphous carbon films prepared by unbalanced magnetron sputtering

    SciTech Connect

    Shi, J.R.

    2006-02-01

    Nitrogenated amorphous carbon (a-CN{sub x}) films were prepared by unbalanced magnetron sputtering (UBMS) at different N{sub 2}/Ar gas flow rate ratios and different bias voltages. The films were characterized using x-ray photoelectron spectroscopy, Raman scattering, nanoindenter, atomic force microscopy nanoscratch, and contact angle measurement. It was found that a negative bias of 150 V is the optimal condition for the formation of sp{sup 3} bonded carbon atoms. As the N{sub 2}/Ar flow rate ratio changes from 0 to 0.47, the nitrogen to carbon ratio in deposited films increases from 0 to 0.22, and the sp{sup 3} fraction of carbon atoms decreases from 0.51 to 0.28. The pure carbon film has the highest sp{sup 3} faction of carbon atoms and therefore the highest hardness and the lowest scratching depth. Comparing to the films prepared by conventional magnetron sputtering, all the a-CN{sub x} films prepared by UBMS show a lower scratching depth. The a-CN{sub x} films have a hydrophilic characteristic with a surface free energy from 56.6 to 65.6 mN/m and a predominant polar component.

  1. Carbon film deposition on SnO{sub 2}/Si(111) using DC unbalanced magnetron sputtering

    SciTech Connect

    Aji, A. S.; Darma, Y.

    2013-09-09

    In this paper, carbon deposition on SnO{sub 2} layer using DC unbalanced magnetron-sputtering technique at low temperature has been systematically studied. Sputtering process were carried out at pressure of 4.6×10{sup −2} Torr by keeping the substrate temperature at 300 °C. SnO{sub 2} were growth on silicon (111) substrate using thermal evaporation and continuing with dry oxidation of Sn at 225 °C. Thermal evaporation for high purity Sn was conducted by maintain the current source as high as 40 ampere. The quality of SnO{sub 2} on Si(111) and the characteristic of carbon thin film on SnO{sub 2} were analized by mean XRD, FTIR and Raman spectra. XRD analysis shows that SnO{sub 2} film is growth uniformly on Si(111). FTIR and Raman spectra confirm the formation of thin film carbon on SnO{sub 2}. Additionally, thermal annealing for some sample series have been performed to study their structural stability. The change of atomic structure due to thermal annealing were analized by Raman and XRD spectra.

  2. Surface treatment effect on Si (111) substrate for carbon deposition using DC unbalanced magnetron sputtering

    SciTech Connect

    Aji, A. S. Sahdan, M. F.; Hendra, I. B.; Dinari, P.; Darma, Y.

    2015-04-16

    In this work, we studied the effect of HF treatment in silicon (111) substrate surface for depositing thin layer carbon. We performed the deposition of carbon by using DC Unbalanced Magnetron Sputtering with carbon pallet (5% Fe) as target. From SEM characterization results it can be concluded that the carbon layer on HF treated substrate is more uniform than on substrate without treated. Carbon deposition rate is higher as confirmed by AFM results if the silicon substrate is treated by HF solution. EDAX characterization results tell that silicon (111) substrate with HF treatment have more carbon fraction than substrate without treatment. These results confirmed that HF treatment on silicon Si (111) substrates could enhance the carbon deposition by using DC sputtering. Afterward, the carbon atomic arrangement on silicon (111) surface is studied by performing thermal annealing process to 900 °C. From Raman spectroscopy results, thin film carbon is not changing until 600 °C thermal budged. But, when temperature increase to 900 °C, thin film carbon is starting to diffuse to silicon (111) substrates.

  3. DIP–STR: Highly Sensitive Markers for the Analysis of Unbalanced Genomic Mixtures

    PubMed Central

    Castella, Vincent; Gervaix, Joëlle; Hall, Diana

    2013-01-01

    Samples containing highly unbalanced DNA mixtures from two individuals commonly occur both in forensic mixed stains and in peripheral blood DNA microchimerism induced by pregnancy or following organ transplant. Because of PCR amplification bias, the genetic identification of a DNA that contributes trace amounts to a mixed sample represents a tremendous challenge. This means that standard genetic markers, namely microsatellites, also referred as short tandem repeats (STR), and single-nucleotide polymorphism (SNP) have limited power in addressing common questions of forensic and medical genetics. To address this issue, we developed a molecular marker, named DIP–STR that relies on pairing deletion–insertion polymorphisms (DIP) with STR. This novel analytical approach allows for the unambiguous genotyping of a minor component in the presence of a major component, where DIP–STR genotypes of the minor were successfully procured at ratios up to 1:1,000. The compound nature of this marker generates a high level of polymorphism that is suitable for identity testing. Here, we demonstrate the power of the DIP–STR approach on an initial set of nine markers surveyed in a Swiss population. Finally, we discuss the limitations and potential applications of our new system including preliminary tests on clinical samples and estimates of their performance on simulated DNA mixtures. PMID:23355272

  4. Echocardiographic features defining right dominant unbalanced atrioventricular septal defect: a multi-institutional Congenital Heart Surgeons' Society study.

    PubMed

    Cohen, Meryl S; Jegatheeswaran, Anusha; Baffa, Jeanne M; Gremmels, David B; Overman, David M; Caldarone, Christopher A; McCrindle, Brian W; Mertens, Luc

    2013-07-01

    Definition and management of right dominant unbalanced atrioventricular septal defect (AVSD) remains challenging because unbalance entails a spectrum of left heart hypoplasia. Previous work has highlighted atrioventricular valve (AVV) index as a reasonable defining echocardiographic measure. We sought to assess which additional echocardiographic features might provide further characterization. From a multi-institutional cohort of complete AVSD, 52 preoperative echocardiograms of patients with presumed right dominant unbalanced AVSD (based on AVV index) and 60 randomly selected preoperative echocardiograms from patients with presumed balanced AVSD were reviewed. Cluster analysis of echocardiographic variables was used to group patients with similar features. Discriminant function analysis was used to explore which variables differentiated these groups. Three groups were identified from the cluster analysis. Echocardiographic variables that differentiated these groups were right ventricle:left ventricle inflow angle, LV width/LV length, left AVV color diameter at smallest inflow, left AVV color diameter at annulus, right AVV overriding left atrium, and LV width. Based on procedures and outcomes, 1 group likely represented balanced patients, whereas 2 groups with similar outcomes likely represented unbalanced patients. The dominant differentiating echocardiographic variable between the 3 cluster groups was the right ventricle:LV inflow angle (partial R²=0.86), defined as the angle between the base of the right ventricle and LV free wall, using the crest of the ventricular septum as apex of the angle. The angle of right ventricle/LV inflow and other surrogates of inflow may be important defining echocardiographic measures of right dominant unbalanced AVSD, although confirmation is needed.

  5. Tracking performance of the polarity-type costas loop at low SNR for UQPSK signal. [Unbalanced Quadri-PSK

    NASA Technical Reports Server (NTRS)

    Park, Y. H.

    1981-01-01

    Carrier tracking performance of the polarity type costas loop is analyzed for unbalanced quadriphase-shift-keyed (UQPSK) signals at low SNR. Squaring losses for various SNR, IF bandwidth, and data rate ratios are presented. The RMS phase jitter for a particular loop is computed for various I and Q channel power and data rate ratios. Experimental results using a breadboard costas loop are also included.

  6. Experimental and Theoretical Study of Flow Fields and Store Forces in Close Proximity to a Triple Ejection Rack at Transonic Speeds.

    DTIC Science & Technology

    1980-09-01

    present the test conditions. This will be followed by a series of sub-sections, each one devoted to describing a specific type of data. Information is...particular angle of attack. The store was then placed as close as possible to the carriage position at TER station number 1. Data were taken at a series of...and the Xp axis are parallel. Data were obtained by making axial traverses at a series of Yp, Zp positions. These locations are shown in the following

  7. Unbalanced Oxidant-Antioxidant Status: A Potential Therapeutic Target for Coronary Chronic Total Occlusion in Very Old Patients

    PubMed Central

    2016-01-01

    Unbalanced oxidant and antioxidant status played an important role in myocardial infarction. The present study was a clinical trial combined preclinically with targeted agent against cardiovascular injuries and ischemia in vivo model. We tried to confirm the association of unbalanced oxidant and antioxidant status with coronary chronic total occlusion (CTO) in 399 very old patients (80~89 years) and investigated the potential therapeutic value of purified polysaccharide from endothelium corneum gigeriae galli (PECGGp). We analyzed levels of circulating superoxide dismutase 3 (SOD3), nitric oxide (NO), endothelial nitric oxide synthase (eNOS), and malondialdehyde (MDA) in very old patients with coronary CTO. Levels of SOD3, NO, eNOS, and MDA in the cardiac tissue were measured in myocardial infarction rats. Levels of SOD3, eNOS, and NO were lowered (p < 0.001) and levels of MDA were increased (p < 0.001). PECGGp treatment increased levels of SOD3, eNOS, and NO (p < 0.01) in cardiac tissue, while decreasing levels of MDA (p < 0.01). PECGGp may suppress unbalanced oxidant and antioxidant status in infarcted myocardium by inhibiting levels of MDA and elevating NO, eNOS, and SOD3 levels. PECGGp could be considered as a potential therapeutic agent for coronary CTO in very old patients. PMID:28044093

  8. Characterization of an unbalanced de novo rearrangement, initially by dinucleotide repeat polymorphism typing and subsequent confirmation by FISH

    SciTech Connect

    Zhao, J.; Gordon, P.L.; Wilroy, R.S.

    1994-09-01

    Unbalanced de novo rearrangements not amenable to characterization by conventional cytogenetics can be elucidated using molecular techniques. By microsatellite polymorphism typing, we initially determined the origin and composition of an unbalanced de novo translocation (46,XX,15q+) in a child with multiple congenital anomalies. Microsatellite polymorphism for D5S208 (localized to 5p15) and polymerase chain reaction (PCR) analysis showed that the extra segment originated from the short arm of chromosome 5. Amplification of patient`s DNA with primers for dinucleotide repeats D5S350 and D5S118 showed that most of the short arm of chromosome 5 was present in three copies. The PCR findings were then reconfirmed by a battery of fluorescence in situ hybridizations (FISH). FISH analyses were further helpful in accurately defining the precise trisomic region as well as elucidating the dicentric nature of 46,XX,-15,+der dic (15)t(5;15)(q11.1;p12) de novo translocation. This work demonstrates the benefit of microsatellite polymorphism typing for the identification and characterization of de novo unbalanced rearrangements and apparent tandem duplications in which conventional cytogenetic techniques are usually uninformative. Such study design in cytogenetically equivocal cases could undoubtedly aid in patient management, family counseling and benefit gene mapping studies through accurate genotype-phenotype correlation.

  9. [Evaluation of the efficiency of balanced and unbalanced crystalloid solutions used in the program of infusion therapy in patients with blood loss].

    PubMed

    Lukach, V N; Girsh, A O; Stukanov, M M; Glushchenko, A V

    2009-01-01

    The authors present a comparative assessment of the efficiency of balanced and unbalanced crystalloid solutions used in the program of infusion therapy in patients with blood loss. It was found that infusion therapy with unbalanced crystalloid solution facilitated the appearance of electrolytic changes and decrease of pH of venous blood while infusion therapy with balanced crystalloid solution did not cause negative changes of the water-electrolytic and acid-base balance.

  10. EDITORIAL: Close contact Close contact

    NASA Astrophysics Data System (ADS)

    Demming, Anna

    2010-07-01

    means to produce nanoscale device elements, such as carbon nanotube transistors [5] and high-density memory crossbar circuits [6]. Recently, the use of scanning tunnelling microscopes has broached a new field of research, which is currently attracting enormous interest—single molecule detection. In issue 25 of Nanotechnology researchers in Houston reported unprecedented sensitivities using localized surface plasmon resonance shifts of gold bipyramids to detect concentrations of substances down to the single molecule level [7]. In issue 26 a collaboration of researchers from the US and Czech Republic describe a different approach, namely tunnelling recognition. In their topical review they describe hydrogen-bond mediated tunnelling and the associated experimental methods that facilitate the detection of single molecules in a tunnel junction using chemically functionalized electrodes [8]. The nanoworld depicted by scanning probe microgaphs over 20 years ago may have looked as extraterrestrial as any science fiction generated alien terrain, but though study and analysis these nano-landscapes have become significantly less alien territory. The work so far to unveil the intricacies of electronic contact has been a story of progress in investigating this new territory and manipulating the mechanisms that govern it to formulate new devices and delve deeper into phenomena at the nanoscale. References [1] Binning G, Rohrer H, Gerber Ch and Weibel E 1982 Phys. Rev. Lett. 49 57-61 [2] X D Cui, X Zarate, J Tomfohr, O F Sankey, A Primak, A L Moore, T A Moore, D Gust, G~Harris and S M Lindsay 2002 Nanotechnology 13 5-14 [3] Martin C A, van Ruitenbeek J M and van der Zant S J H 2010 Nanotechnology 21 265201 [4] Davis J J and Hanyu Y 2010 Nanotechnology 21 265302 [5] Tans S J, Verschueren A R M and Dekker C 1998 Nature 393 49-52 [6] Chen Y, Jung G-Y, Ohlberg D A A, Li X, Stewart D R, Jeppesen J O, Nielsen K A, Stoddart J F and Williams R S 2003 Nanotechnology 14 462-8 [7] Mayer K M

  11. E. coli electroeradication on a closed loop circuit by using milli-, micro- and nanosecond pulsed electric fields: comparison between energy costs.

    PubMed

    Guionet, Alexis; David, Fabienne; Zaepffel, Clément; Coustets, Mathilde; Helmi, Karim; Cheype, Cyril; Packan, Denis; Garnier, Jean-Pierre; Blanckaert, Vincent; Teissié, Justin

    2015-06-01

    One of the different ways to eradicate microorganisms, and particularly bacteria that might have an impact on health consists in the delivery of pulsed electric fields (PEFs). The technologies of millisecond (ms) or microsecond (μs) PEF are still well known and used for instance in the process of fruit juice sterilization. However, this concept is costly in terms of delivered energy which might be too expensive for some other industrial processes. Nanosecond pulsed electric fields (nsPEFs) might be an alternative at least for lower energetic cost. However, only few insights were available and stipulate a gain in cost and in efficiency as well. Using Escherichia coli, the impact of frequency and low rate on eradication and energy consumption by msPEF, μsPEF and nsPEF have been studied and compared. While a 1 log10 was reached with an energy cost of 100 and 158 kJ/L with micro- and millisecond PEFs respectively, nsPEF reached the reduction for similar energy consumption. The best condition was obtained for a 1 log10 deactivation in 0.5h, for energy consumption of 143 kJ/L corresponding to 0.04 W · h when the field was around 100 kV/cm. Improvement can also be expected by producing a generator capable to increase the electric field.

  12. Dynamic polarization of light halo nuclei in strong fields: {sup 6}He+{sup 209}Bi elastic scattering below and close to the Coulomb barrier

    SciTech Connect

    Borowska, L.; Terenetsky, K.; Verbitsky, V.; Fritzsche, S.

    2007-09-15

    The elastic scattering of light halo nuclei in the field of heavy targets has been studied for collision energies below the Coulomb barrier. Based on the assumption that the neutron halo follows the projectile adiabatically along its classical trajectory, a dynamic polarization potential is derived which describes both the (electrical) polarization as well as the breakup of the projectile in the field of the target. Detailed computations have been carried out for the elastic scattering of {sup 6}He+{sup 209}Bi at energies between 14.7 MeV and 19.1 MeV near to the Coulomb barrier. It is demonstrated that the polarization of the halo nucleus leads to a clear decrease of the (elastic) scattering cross section in excellent agreement with a recent measurement by Aguilera et al. [Phys. Rev. Lett. 84, 5058 (2000)].

  13. Two encounters with the flank low-latitude boundary layer - Further evidence for closed field topology and investigation of the internal structure

    NASA Technical Reports Server (NTRS)

    Traver, D. P.; Mitchell, D. G.; Williams, D. J.; Frank, L. A.; Huang, C. Y.

    1991-01-01

    The structure of the flank low-latitude boundary layer (LLBL) is examined through differential energy spectra and particle angular anisotropies for traversals of the dawn flank (December 19, 1977) and dusk flank (July 7, 1978) during periods of predominantly northward magnetosheath field orientation. Spectra are presented that were obtained from combined ISEE 1 low-energy-proton and electron-differential-energy-analyzer and medium-energy-particle-instrument data extending over the 200-eV/q to 2-MeV energy range for the plasma sheet, stagnation region, outer LLBL, and magnetosheath regions. The stagnation region and the outer LLBL are each a mixture of plasma-sheet and magnetosheath populations, but the stagnation region contains a relatively higher fraction of plasma sheet particles, consistent with its placement earthward of the outer LLBL. Evidence for energization of thermal electrons appears during the dusk flank crossing. Bidirectional field-aligned ion distributions are observed with typically 5-to-1 enhancement of the flux along the magnetic field during certain portions of the dusk flank crossing.

  14. Unbalanced risk factors, could compromise the effectiveness of physical training in patients with intermittent claudication?

    PubMed

    Leone, A; Laudani, R; Definite, G; Martini, R; Andreozzi, G M

    2009-04-01

    The correction of atherosclerotic risk factors is the unavoidable assumption to assure the maximal effectiveness and duration of the results of any therapeutic intervention (pharmacological and surgical) for the treatment of intermittent claudication. Aim of this study has been to verify if the presence/absence of risk factors and the degree of their correction could compromise the responsiveness of claudicant patients to the supervised physical training. Initial (IDC), absolute (ACD) claudication distance, and recovery time (RT) have been measured by maximal treadmill exercise in 74 claudicants. The measurements have been repeated after 18 days of supervised physical training consisting of a daily walk reaching either a distance goal of 1-2 km or a time goal of at least 30 min. The working load of each single training session has been tailored at 60-70% of the ACD measured by a non-maximal treadmill exercise. The patients' cohort has been stratified in 7 groups and 18 sub-groups (no smokers, smokers in the past, still smokers, no-diabetics, well balanced and unbalanced diabetes, absent, well balanced and unbalanced hypercholesterolemia, normal weight, over weight and light obesity, hypertensive and no-hypertensive, with and without previous myocardial infarction and TIAs or stroke). The mean and standard error of ICD, ACD and RT before and after 18 days of physical training have been calculated and compared with Student's t test in each group and sub-group. On the data before and after training of ICD, ACD and RT of each group of risk factors the multivariate analysis of the variance has been carried out by analysis of variance (ANOVA). All the analyses were considered significant when the P value was less than 0.05. ICD values increased from 55.12 to 121.86 m, ACD from 103.16 to 191.58 m, RT reduced from 204.04 to 87.46 s, confirming the relevant (P<0.0001) effectiveness of supervised physical training on the walking capacity of claudicant patients. The

  15. Histological Changes on Liver Glycogen Storage in Mice (Mus musculus) Caused by Unbalanced Diets

    PubMed Central

    Ulusoy, Esma; Eren, Banu

    2008-01-01

    Weight-losing diets have appealed to people who want to lose weight in the short-term. They usually apply high-protein (HP) diets (like Atkin’s, Stillman’s, Scarsdale) which they practice for 2 weeks or so. Unfortunately, these people who have rapid weight loss return to their old habits and quickly regain the weight lost. We have shown in previous work that actually these weight losses have been associated with body fluids, protein and glycogen storage. In our study, we examined the effect of unbalanced diet—related to an HP diet- on liver glycogen storage. For this study 40 Swiss albino mice consisting of two groups were used. The first group (HPSD) was fed with 25% HP for fifteen days and then were fed standard meals for the remaining 15 days; the other group was fed with standard meals throughout. The two groups were fed their respective diets for 30 days. At the end of 15th, 20th, 25th and 30th days 5 from each group were killed with cervical dislocation. The livers were removed perfused and then fixated. There were major differences in weight between the first and the fifteenth days. We detected remarkable increase in the weight gain of mice in the remaining 15 days. Glycogen storage was significantly reduced in HPSD (15) stained with PAS. In the others 20th, 25th and 30th days abnormally dense glycogen deposits were observed. Vacuoles in the hepatocyte cytoplasm, brownish deposits within hepatocytes, wide sinusoids, macrovesiculler steatosis structures and hydropic degeneration were observed in PAS and H&E stained HPSD group. As a result for the HPSD group a significant decrement in glycogen storage at the 15th day and also an accumulation of excessive amounts of glycogen deposits in mice liver was observed in the normal feeding phase. PMID:21876654

  16. A comparison of balanced and unbalanced crystalloid solutions in surgery patient outcomes.

    PubMed

    Kuca, Tomas; Butler, Michael B; Erdogan, Mete; Green, Robert S

    2016-11-14

    The objective of this study was to evaluate adverse patient outcomes associated with the choice of intravenous fluid administered during general anaesthesia. This study was a retrospective chart review of vascular surgery patients at a Canadian tertiary care hospital. Patients were separated into three groups: those who were intraoperatively administered normal saline (NS), balanced crystalloids, or a combination of both solutions. Multivariate analysis was performed to determine association between volume of each fluid type administered and adverse outcomes including in-hospital mortality, prolonged intensive care unit admission, vasopressor requirement, ventilator requirement, hemodialysis requirement, and a composite endpoint of any of these adverse events occurring. Overall, 796 vascular surgery patients were included in the analysis. There were 425 patients who received balanced crystalloids, 158 patients who received NS, and 213 patients received both balanced crystalloids and NS. Groups were similar in age (P=0.06), but varied in gender (P<0.001) and overall health (ASA≥2; P=0.027). The most common adverse event was ventilator requirement (NS: 27.9%, balanced: 7.5%, both: 38.0%; P<0.001). Mortality was lowest in the group that received balanced fluids (NS: 12.0%, balanced: 5.9%, both: 10.8%; P=0.018). Patients who were administered NS or both fluids were more likely to reach the composite endpoint than patients receiving balanced crystalloid alone. The administration of an unbalanced crystalloid solution was associated with poor patient outcomes in our study population. Copyright © 2016 Société française d'anesthésie et de réanimation (Sfar). Published by Elsevier Masson SAS. All rights reserved.

  17. Catastrophic Unbalanced Genome Rearrangements Cause Somatic Loss of Berry Color in Grapevine.

    PubMed

    Carbonell-Bejerano, Pablo; Royo, Carolina; Torres-Pérez, Rafael; Grimplet, Jérôme; Fernandez, Lucie; Franco-Zorrilla, José Manuel; Lijavetzky, Diego; Baroja, Elisa; Martínez, Juana; García-Escudero, Enrique; Ibáñez, Javier; Martínez-Zapater, José Miguel

    2017-10-01

    Grape (Vitis vinifera) color somatic variants that can be used to develop new grapevine cultivars occasionally appear associated with deletion events of uncertain origin. To understand the mutational mechanisms generating somatic structural variation in grapevine, we compared the Tempranillo Blanco (TB) white berry somatic variant with its black berry ancestor, Tempranillo Tinto. Whole-genome sequencing uncovered a catastrophic genome rearrangement in TB that caused the hemizygous deletion of 313 genes, including the loss of the functional copy for the MYB transcription factors required for anthocyanin pigmentation in the berry skin. Loss of heterozygosity and decreased copy number delimited interspersed monosomic and disomic regions in the right arm of linkage groups 2 and 5. At least 11 validated clustered breakpoints involving intrachromosomal and interchromosomal translocations between three linkage groups flanked the deleted fragments, which, according to segregation analyses, are phased in a single copy of each of the affected chromosomes. These hallmarks, along with the lack of homology between breakpoint joins and the randomness of the order and orientation of the rearranged fragments, are all consistent with a chromothripsis-like pattern generated after chromosome breakage and illegitimate rejoining. This unbalanced genome reshuffling has additional consequences in reproductive development. In TB, lack of sexual transmission of rearranged chromosomes associates with low gamete viability, which compromises fruit set and decreases fruit production. Our findings show that catastrophic genome rearrangements arise spontaneously and stabilize during plant somatic growth. These dramatic rearrangements generate new interesting phenotypes that can be selected for the improvement of vegetatively propagated plant species. © 2017 American Society of Plant Biologists. All Rights Reserved.

  18. Numerical Study of Pressure Field in Laterally Closed Industrial Buildings with Curved Metallic Roofs due to the Wind Effect by FEM and European Rule Comparison

    NASA Astrophysics Data System (ADS)

    Nieto, P. J. García; del Coz Díaz, J. J.; Vilán, J. A. Vilán; Placer, C. Casqueiro

    2009-08-01

    In this paper, an evaluation of distribution of the air pressure is determined throughout the laterally closed industrial buildings with curved metallic roofs due to the wind effect by the finite element method (FEM). The non-linearity is due to Reynolds-averaged Navier-Stokes (RANS) equations that govern the turbulent flow. The Navier-Stokes equations are non-linear partial differential equations and this non-linearity makes most problems difficult to solve and is part of the cause of turbulence. The RANS equations are time-averaged equations of motion for fluid flow. They are primarily used while dealing with turbulent flows. Turbulence is a highly complex physical phenomenon that is pervasive in flow problems of scientific and engineering concern like this one. In order to solve the RANS equations a two-equation model is used: the standard k-ɛ model. The calculation has been carried out keeping in mind the following assumptions: turbulent flow, an exponential-like wind speed profile with a maximum velocity of 40 m/s at 10 m reference height, and different heights of the building ranging from 6 to 10 meters. Finally, the forces and moments are determined on the cover, as well as the distribution of pressures on the same one, comparing the numerical results obtained with the Spanish CTE DB SE-AE, Spanish NBE AE-88 and European standard rules, giving place to the conclusions that are exposed in the study.

  19. Can Mixed-Species Groups Reduce Individual Parasite Load? A Field Test with Two Closely Related Poeciliid Fishes (Poecilia reticulata and Poecilia picta)

    PubMed Central

    Dargent, Felipe; Torres-Dowdall, Julián; Scott, Marilyn E.; Ramnarine, Indar; Fussmann, Gregor F.

    2013-01-01

    Predation and parasitism are two of the most important sources of mortality in nature. By forming groups, individuals can gain protection against predators but may increase their risk of being infected with contagious parasites. Animals might resolve this conflict by forming mixed-species groups thereby reducing the costs associated with parasites through a relative decrease in available hosts. We tested this hypothesis in a system with two closely related poeciliid fishes (Poecilia reticulata and Poecilia picta) and their host-specific monogenean ectoparasites (Gyrodactylus spp.) in Trinidad. Fish from three different rivers were sampled from single and mixed-species groups, measured and scanned for Gyrodactylus. The presence and abundance of Gyrodactylus were lower when fish of both species were part of mixed-species groups relative to single-species groups. This is consistent with the hypothesis that mixed-species groups provide a level of protection against contagious parasites. We discuss the importance of potentially confounding factors such as salinity and individual fish size. PMID:23437237

  20. Can mixed-species groups reduce individual parasite load? A field test with two closely related poeciliid fishes (Poecilia reticulata and Poecilia picta).

    PubMed

    Dargent, Felipe; Torres-Dowdall, Julián; Scott, Marilyn E; Ramnarine, Indar; Fussmann, Gregor F

    2013-01-01

    Predation and parasitism are two of the most important sources of mortality in nature. By forming groups, individuals can gain protection against predators but may increase their risk of being infected with contagious parasites. Animals might resolve this conflict by forming mixed-species groups thereby reducing the costs associated with parasites through a relative decrease in available hosts. We tested this hypothesis in a system with two closely related poeciliid fishes (Poecilia reticulata and Poecilia picta) and their host-specific monogenean ectoparasites (Gyrodactylus spp.) in Trinidad. Fish from three different rivers were sampled from single and mixed-species groups, measured and scanned for Gyrodactylus. The presence and abundance of Gyrodactylus were lower when fish of both species were part of mixed-species groups relative to single-species groups. This is consistent with the hypothesis that mixed-species groups provide a level of protection against contagious parasites. We discuss the importance of potentially confounding factors such as salinity and individual fish size.

  1. Three dimensional equilibrium solutions for a current-carrying reversed-field pinch plasma with a close-fitting conducting shell

    DOE PAGES

    Koliner, J. J.; Boguski, J.; Anderson, J. K.; ...

    2016-03-25

    In order to characterize the Madison Symmetric Torus (MST) reversed-field pinch(RFP)plasmas that bifurcate to a helical equilibrium, the V3FIT equilibrium reconstruction code was modified to include a conducting boundary. RFPplasmas become helical at a high plasma current, which induces large eddy currents in MST's thick aluminum shell. The V3FIT conducting boundary accounts for the contribution from these eddy currents to external magnetic diagnostic coil signals. This implementation of V3FIT was benchmarked against MSTFit, a 2D Grad-Shafranov solver, for axisymmetric plasmas. The two codes both fit B measurement loops around the plasma minor diameter with qualitative agreement between each other andmore » the measured field. Fits in the 3D case converge well, with q-profile and plasma shape agreement between two distinct toroidal locking phases. Greater than 60% of the measured n = 5 component of B at r = a is due to eddy currents in the shell, as calculated by the conducting boundary model.« less

  2. Three dimensional equilibrium solutions for a current-carrying reversed-field pinch plasma with a close-fitting conducting shell

    SciTech Connect

    Koliner, J. J.; Boguski, J.; Anderson, J. K.; Hanson, J. D.; Chapman, B. E.; Brower, D. L.; Den Hartog, D. J.; Ding, W. X.; Duff, J. R.; Goetz, J. A.; McGarry, M.; Morton, L. A.; Parker, E.

    2016-03-25

    In order to characterize the Madison Symmetric Torus (MST) reversed-field pinch(RFP)plasmas that bifurcate to a helical equilibrium, the V3FIT equilibrium reconstruction code was modified to include a conducting boundary. RFPplasmas become helical at a high plasma current, which induces large eddy currents in MST's thick aluminum shell. The V3FIT conducting boundary accounts for the contribution from these eddy currents to external magnetic diagnostic coil signals. This implementation of V3FIT was benchmarked against MSTFit, a 2D Grad-Shafranov solver, for axisymmetric plasmas. The two codes both fit B measurement loops around the plasma minor diameter with qualitative agreement between each other and the measured field. Fits in the 3D case converge well, with q-profile and plasma shape agreement between two distinct toroidal locking phases. Greater than 60% of the measured n = 5 component of B at r = a is due to eddy currents in the shell, as calculated by the conducting boundary model.

  3. Three dimensional equilibrium solutions for a current-carrying reversed-field pinch plasma with a close-fitting conducting shell

    SciTech Connect

    Koliner, J. J.; Boguski, J. Anderson, J. K.; Chapman, B. E.; Den Hartog, D. J.; Duff, J. R.; Goetz, J. A.; McGarry, M.; Morton, L. A.; Parke, E.; Cianciosa, M. R.; Hanson, J. D.; Brower, D. L.; Ding, W. X.

    2016-03-15

    In order to characterize the Madison Symmetric Torus (MST) reversed-field pinch (RFP) plasmas that bifurcate to a helical equilibrium, the V3FIT equilibrium reconstruction code was modified to include a conducting boundary. RFP plasmas become helical at a high plasma current, which induces large eddy currents in MST's thick aluminum shell. The V3FIT conducting boundary accounts for the contribution from these eddy currents to external magnetic diagnostic coil signals. This implementation of V3FIT was benchmarked against MSTFit, a 2D Grad-Shafranov solver, for axisymmetric plasmas. The two codes both fit B{sub θ} measurement loops around the plasma minor diameter with qualitative agreement between each other and the measured field. Fits in the 3D case converge well, with q-profile and plasma shape agreement between two distinct toroidal locking phases. Greater than 60% of the measured n = 5 component of B{sub θ} at r = a is due to eddy currents in the shell, as calculated by the conducting boundary model.

  4. Three dimensional equilibrium solutions for a current-carrying reversed-field pinch plasma with a close-fitting conducting shell

    NASA Astrophysics Data System (ADS)

    Koliner, J. J.; Cianciosa, M. R.; Boguski, J.; Anderson, J. K.; Hanson, J. D.; Chapman, B. E.; Brower, D. L.; Den Hartog, D. J.; Ding, W. X.; Duff, J. R.; Goetz, J. A.; McGarry, M.; Morton, L. A.; Parke, E.

    2016-03-01

    In order to characterize the Madison Symmetric Torus (MST) reversed-field pinch (RFP) plasmas that bifurcate to a helical equilibrium, the V3FIT equilibrium reconstruction code was modified to include a conducting boundary. RFP plasmas become helical at a high plasma current, which induces large eddy currents in MST's thick aluminum shell. The V3FIT conducting boundary accounts for the contribution from these eddy currents to external magnetic diagnostic coil signals. This implementation of V3FIT was benchmarked against MSTFit, a 2D Grad-Shafranov solver, for axisymmetric plasmas. The two codes both fit Bθ measurement loops around the plasma minor diameter with qualitative agreement between each other and the measured field. Fits in the 3D case converge well, with q-profile and plasma shape agreement between two distinct toroidal locking phases. Greater than 60% of the measured n = 5 component of Bθ at r = a is due to eddy currents in the shell, as calculated by the conducting boundary model.

  5. Lidar Sensor Performance in Closed-Loop Flight Testing of the Morpheus Rocket-Propelled Lander to a Lunar-Like Hazard Field

    NASA Technical Reports Server (NTRS)

    Roback, Vincent E.; Pierrottet, Diego F.; Amzajerdian, Farzin; Barnes, Bruce W.; Hines, Glenn D.; Petway, Larry B.; Brewster, Paul F.; Kempton, Kevin S.; Bulyshev, Alexander E.

    2015-01-01

    For the first time, a suite of three lidar sensors have been used in flight to scan a lunar-like hazard field, identify a safe landing site, and, in concert with an experimental Guidance, Navigation, and Control (GN&C) system, guide the Morpheus autonomous, rocket-propelled, free-flying test bed to a safe landing on the hazard field. The lidar sensors and GN&C system are part of the Autonomous Precision Landing and Hazard Detection and Avoidance Technology (ALHAT) project which has been seeking to develop a system capable of enabling safe, precise crewed or robotic landings in challenging terrain on planetary bodies under any ambient lighting conditions. The 3-D imaging flash lidar is a second generation, compact, real-time, air-cooled instrument developed from a number of cutting-edge components from industry and NASA and is used as part of the ALHAT Hazard Detection System (HDS) to scan the hazard field and build a 3-D Digital Elevation Map (DEM) in near-real time for identifying safe sites. The flash lidar is capable of identifying a 30 cm hazard from a slant range of 1 km with its 8 cm range precision at 1 sigma. The flash lidar is also used in Hazard Relative Navigation (HRN) to provide position updates down to a 250m slant range to the ALHAT navigation filter as it guides Morpheus to the safe site. The Doppler Lidar system has been developed within NASA to provide velocity measurements with an accuracy of 0.2 cm/sec and range measurements with an accuracy of 17 cm both from a maximum range of 2,200 m to a minimum range of several meters above the ground. The Doppler Lidar's measurements are fed into the ALHAT navigation filter to provide lander guidance to the safe site. The Laser Altimeter, also developed within NASA, provides range measurements with an accuracy of 5 cm from a maximum operational range of 30 km down to 1 m and, being a separate sensor from the flash lidar, can provide range along a separate vector. The Laser Altimeter measurements are also

  6. Field campaigns of the autonomous, closed-path, airborne TDLAS Hygrometer SEALDH-II and traceability to the German Primary Humidity Standards.

    NASA Astrophysics Data System (ADS)

    Buchholz, Bernhard; Ebert, Volker

    2014-05-01

    Airborne hygrometry is often demanded in scientific flight campaigns to provide datasets for environmental modeling or to correct for water vapor dilution or cross sensitivity effects in other gas analytical techniques. Water vapor measurements, however, are quite challenging due to the large dynamic range in the atmosphere (between 2 and 40000 ppmv) and the high spatio-temporal variability. Airborne hygrometers therefore need to combine a large measurement range with high temporal resolution to resolve - at typical airspeeds of 500 to 900 km/h - atmospheric gradients of several 1000 ppmv/s. Especially during the ascent into the upper troposphere, hygrometers need to work at high gas exchange rates to minimize water vapor adsorption effects. On the other hand, water vapor sensors are difficult to calibrate due to the strong water adsorption and the lack of bottled reference gas standards, which requires pre- or/and post-flight field calibrations. Recently in-flight calibration using an airborne H2O generator was demonstrated, which minimizes calibration drift but still imposes a lot of additional work and hardware to the experiments, since these kind of calibrations just transfer the accuracy level issues to the in-flight calibration-source. To make things worse, the low gas flow (1-5 std l/min, compared with up to 100 std l/min in flight for fast response instruments) adheres critical questions of wall absorption/desorption of the source and instrument even during the calibration process. The national metrological institutes (NMIs) maintain a global metrological water vapor scale which is defined via national primary humidity generators. These provide for calibration purposes well-defined, accurate water vapor samples of excellent comparability and stability traced back to the SI-units. The humidity calibration chain is maintained via high accuracy (but rather slow) Dew-Point-Mirror-Hygrometers as transfer standards. These provide a traceable performance and

  7. Predictor-based multivariable closed-loop system identification of the EXTRAP T2R reversed field pinch external plasma response

    NASA Astrophysics Data System (ADS)

    Olofsson, K. Erik J.; Brunsell, Per R.; Rojas, Cristian R.; Drake, James R.; Hjalmarsson, Håkan

    2011-08-01

    The usage of computationally feasible overparametrized and nonregularized system identification signal processing methods is assessed for automated determination of the full reversed-field pinch external plasma response spectrum for the experiment EXTRAP T2R. No assumptions on the geometry of eigenmodes are imposed. The attempted approach consists of high-order autoregressive exogenous estimation followed by Markov block coefficient construction and Hankel matrix singular value decomposition. It is seen that the obtained 'black-box' state-space models indeed can be compared with the commonplace ideal magnetohydrodynamics (MHD) resistive thin-shell model in cylindrical geometry. It is possible to directly map the most unstable autodetected empirical system pole to the corresponding theoretical resistive shell MHD eigenmode.

  8. Lidar Sensor Performance in Closed-Loop Flight Testing of the Morpheus Rocket-Propelled Lander to a Lunar-Like Hazard Field

    NASA Technical Reports Server (NTRS)

    Roback, V. Eric; Pierrottet, Diego F.; Amzajerdian, Farzin; Barnes, Bruce W.; Bulyshev, Alexander E.; Hines, Glenn D.; Petway, Larry B.; Brewster, Paul F.; Kempton, Kevin S.

    2015-01-01

    For the first time, a suite of three lidar sensors have been used in flight to scan a lunar-like hazard field, identify a safe landing site, and, in concert with an experimental Guidance, Navigation, and Control (GN&C) system, help to guide the Morpheus autonomous, rocket-propelled, free-flying lander to that safe site on the hazard field. The lidar sensors and GN&C system are part of the Autonomous Precision Landing and Hazard Detection and Avoidance Technology (ALHAT) project which has been seeking to develop a system capable of enabling safe, precise crewed or robotic landings in challenging terrain on planetary bodies under any ambient lighting conditions. The 3-D imaging Flash Lidar is a second generation, compact, real-time, aircooled instrument developed from a number of components from industry and NASA and is used as part of the ALHAT Hazard Detection System (HDS) to scan the hazard field and build a 3-D Digital Elevation Map (DEM) in near-real time for identifying safe sites. The Flash Lidar is capable of identifying a 30 cm hazard from a slant range of 1 km with its 8 cm range precision (1-s). The Flash Lidar is also used in Hazard Relative Navigation (HRN) to provide position updates down to a 250m slant range to the ALHAT navigation filter as it guides Morpheus to the safe site. The Navigation Doppler Lidar (NDL) system has been developed within NASA to provide velocity measurements with an accuracy of 0.2 cm/sec and range measurements with an accuracy of 17 cm both from a maximum range of 2,200 m to a minimum range of several meters above the ground. The NDLâ€"TM"s measurements are fed into the ALHAT navigation filter to provide lander guidance to the safe site. The Laser Altimeter (LA), also developed within NASA, provides range measurements with an accuracy of 5 cm from a maximum operational range of 30 km down to 1 m and, being a separate sensor from the Flash Lidar, can provide range along a separate vector. The LA measurements are also fed

  9. A field trial of spinosad for the treatment and prevention of flea infestation in shepherd dogs living in close proximity to flea-infested sheep.

    PubMed

    Saridomichelakis, Manolis N; Chatzis, Manolis K; Petanides, Theodoros; Papadopoulos, Elias

    2015-06-12

    Three flea species, Pulex irritans, Ctenocephalides canis and C. felis parasitize shepherd dogs living on sheep farms in Greece. The aim of this randomized, blinded, placebo-controlled trial was to examine the efficacy of spinosad, when administered three times every 4 weeks, as the only intervention to treat and prevent flea infestations in shepherd dogs living on sheep farms. Thirty dogs living on sheep farms and infested by at least 24 fleas were randomly allocated into equal groups. Group A dogs received spinosad (45-70 mg/kg body weight), every 4 weeks for three administrations, whereas Group B dogs were placebo-treated. Flea counting was performed at the beginning of the trial (day 0) and after 14, 28, 56 and 84 days. The first five fleas from each dog and 2-6 fleas collected from 5-11 sheep were used for species identification. The percentage of dogs with zero flea counts was significantly higher in group A than in group B at days 14, 28, 56 and 84 and flea counts were significantly lower in group A than in group B at days 14, 28, 56 and 84. In group A, flea counts were significantly lower at days 14, 28, 56 and 84 compared to day 0 whereas there were no changes in flea counts of group B dogs. The percent efficacy of spinosad for the treatment and prevention of flea infestation was higher than 98% (arithmetic means) or higher than 99% (geometric means) throughout the study. No adverse reactions were recorded. C. canis was the predominant flea species of dogs at day 0. In group A the relative abundance of C. felis increased at day14 whereas in group B the relative abundance of P. irritans increased at days 14, 28, 56 and 84. Spinosad is safe and effective for the treatment of C. canis and C. felis infestations and for the prevention of P. irritans, C. canis and C. felis infestations in shepherd dogs living in close proximity to sheep.

  10. Gaseous deposition contributes to the contamination of surface waters by pesticides close to treated fields. A process-based model study.

    PubMed

    Bedos, Carole; Loubet, Benjamin; Barriuso, Enrique

    2013-12-17

    The contribution of atmospheric pathways to surface waters contamination by pesticides has been demonstrated. At the local scale, modeling approaches as well as measurements show situations where the contribution of gaseous dry deposition is of the same order or even higher than the drift contribution. The approach presented here consists in estimating the gaseous emissions of pesticides applied in the field, their atmospheric dispersion, and finally their gaseous deposition into aquatic ecosystems at the local scale by running process-based models, that is, the one-dimensional model for pesticide volatilization following application on bare soil (Volt'Air) and the local-scale dispersion and deposition model (FIDES-2D), adapted for pesticides. A significant number of scenarios describes contrasted situations in terms of pedoclimatic conditions (covering 9 years of meteorological data), periods of pesticide application per year, physicochemical properties of the pesticides, and spatial configurations. The identification of the main factors governing gaseous deposition led to the definition of an effective emission factor which explains a large part of the deposition variability. Based on the model outputs, deposition curves are proposed, as a base for a new tool to assess the contribution of gaseous deposition to nontarget ecosystem contamination.

  11. Accounting for minor storage terms in an attempt to close the measured surface energy balance over a winter wheat field in Southwest Germany

    NASA Astrophysics Data System (ADS)

    Eshonkulov, Ravshan; Poyda, Arne; Ingwersen, Joachim; Streck, Thilo

    2016-04-01

    Studies of energy and water exchange between the land surface and the atmospheric boundary layer are important to understand weather dynamics and climate change. Energy and water fluxes were measured on a winter wheat field in Kraichgau, Southern Germany, using the eddy covariance (EC) method. It is well known that EC measurements suffer from incomplete closure of the energy budget. In addition to the common ground heat flux measurements we measured heat storage in soil and the wheat canopy using high-precision temperature loggers within the EC footprint. Ground heat flux was re-calculated by calorimetric and harmonic analysis. First results obtained by the two methods will be compared. Based on measured data we calculated the contribution of photosynthesis, the air heat storage inside the canopy as well as the atmospheric moisture change to the energy budget. Our results show that accounting for minor storage terms improves the closure of the energy budget, but only to a limited extent. Further investigations will be necessary to identify additional sources of the energy gap typical for EC measurements.

  12. Recommendations for choosing an analysis method that controls Type I error for unbalanced cluster sample designs with Gaussian outcomes.

    PubMed

    Johnson, Jacqueline L; Kreidler, Sarah M; Catellier, Diane J; Murray, David M; Muller, Keith E; Glueck, Deborah H

    2015-11-30

    We used theoretical and simulation-based approaches to study Type I error rates for one-stage and two-stage analytic methods for cluster-randomized designs. The one-stage approach uses the observed data as outcomes and accounts for within-cluster correlation using a general linear mixed model. The two-stage model uses the cluster specific means as the outcomes in a general linear univariate model. We demonstrate analytically that both one-stage and two-stage models achieve exact Type I error rates when cluster sizes are equal. With unbalanced data, an exact size α test does not exist, and Type I error inflation may occur. Via simulation, we compare the Type I error rates for four one-stage and six two-stage hypothesis testing approaches for unbalanced data. With unbalanced data, the two-stage model, weighted by the inverse of the estimated theoretical variance of the cluster means, and with variance constrained to be positive, provided the best Type I error control for studies having at least six clusters per arm. The one-stage model with Kenward-Roger degrees of freedom and unconstrained variance performed well for studies having at least 14 clusters per arm. The popular analytic method of using a one-stage model with denominator degrees of freedom appropriate for balanced data performed poorly for small sample sizes and low intracluster correlation. Because small sample sizes and low intracluster correlation are common features of cluster-randomized trials, the Kenward-Roger method is the preferred one-stage approach.

  13. Unbalanced upregulation of ryanodine receptor 2 plays a particular role in early development of daunorubicin cardiomyopathy

    PubMed Central

    Kucerova, Dana; Doka, Gabriel; Kruzliak, Peter; Turcekova, Katarina; Kmecova, Jana; Brnoliakova, Zuzana; Kyselovic, Jan; Kirchhefer, Uwe; Müller, Frank U; Krenek, Peter; Boknik, Peter; Klimas, Jan

    2015-01-01

    .05), but not of other examined Ca2+ regulating proteins remained. In addition, we observed a significant reduction in alpha-tubulin (by 46% when compared to CON P<0.05). Indicators of oxidative injury were unaffected. In conclusion, unbalanced RyR2 overexpression plays a particular role in early development of daunorubicin cardiomyopathy characterized by discrepant in situ versus in vitro cardiac performance. PMID:26328012

  14. Steady-State Analysis of Parallel-Operated Self-Excited Induction Generators Supplying an Unbalanced Load

    NASA Astrophysics Data System (ADS)

    Radosavljević, Jordan; Klimenta, Dardan; Jevtić, Miroljub

    2012-07-01

    This paper proposed a multi-objective genetic algorithm (MOGA) based approach for determining the steady-state performance characteristics of three-phase self-excited induction generators (SEIGs) operating in parallel and supplying an unbalanced load. The symmetrical component theory is used for the transformation of a complex three-phase generators-capacitances-load system to a simple equivalent circuit. The MOGA has been employed for the determination of unknown variables by minimizing the impedance module of the equivalent circuit. Using this approach, effects of various parameters on the terminal voltage control characteristics are examined for two parallel SEIGs with C2C connection under a single phase load.

  15. Definition and design of an experiment to test raster scanning with rotating unbalanced-mass devices on gimbaled payloads

    NASA Technical Reports Server (NTRS)

    Lightsey, W. D.; Alhorn, D. C.; Polites, M. E.

    1992-01-01

    An experiment designed to test the feasibility of using rotating unbalanced-mass (RUM) devices for line and raster scanning gimbaled payloads, while expending very little power is described. The experiment is configured for ground-based testing, but the scan concept is applicable to ground-based, balloon-borne, and space-based payloads, as well as free-flying spacecraft. The servos used in scanning are defined; the electronic hardware is specified; and a computer simulation model of the system is described. Simulation results are presented that predict system performance and verify the servo designs.

  16. Multicolor banding detects a complex three chromosome, seven breakpoint unbalanced rearrangement in an ICSI-derived fetus with multiple abnormalities.

    PubMed

    Seller, Mary J; Bint, Susan; Kavalier, Fred; Brown, Richard N; Ogilvie, Caroline Mackie

    2006-05-15

    We describe a fetus from an intracytoplasmic sperm injection (ICSI) pregnancy with severe facial clefts, receding jaw, preauricular skin tags, postaxial hexadactyly, bi-lobed right lung, supernumerary cranial bone, and dilated lateral ventricles of the brain. Using a combination of G-banding, fluorescence in situ hybridization (FISH), whole chromosome paints (WCPs), subtelomere probes, and multicolor banding (MCB), the karyotype was found to include a de novo unbalanced highly complex chromosome rearrangement (hCCR) involving chromosomes 3, 12, and 15 with seven breakpoints, and including monosomy for two separate regions of chromosome 12.

  17. Trisomy 2q11.2-->q21.1 resulting from an unbalanced insertion in two generations.

    PubMed Central

    Glass, I A; Stormer, P; Oei, P T; Hacking, E; Cotter, P D

    1998-01-01

    In this communication, we describe two cases of proximal 2q trisomy (2q11.2--> q21.1) resulting from an interchromosomal insertion. The chromosomal origin of the insertion was confirmed by fluorescence in situ hybridisation. An unbalanced karyotype, 46,XX,der(8) ,ins(8;2) (p21.3; q21.1q11.2), was found in the proband and her mother, who both have mild mental retardation, short stature, dysmorphic features, insulin dependent diabetes mellitus, and a psychotic illness. This family is a rare example of direct transmission of a partial autosomal trisomy. Images PMID:9598728

  18. Multi-point observations of large scale perturbations on the open-closed field line boundary during a geomagnetic storm, as observed by the Van Allen Probes and geostationary satellites

    NASA Astrophysics Data System (ADS)

    Grande, Manuel; MacDonald, Elizabeth; Dixon, Patrick

    We discuss a series of lobe entry events observed by the twin Van Allen Probe spacecraft between 0200 and 0515 UTC during the November 14th 2012 geomagnetic storm. During the events Dst was below -100nT with the IMF being strongly southward (Bz = -15nT) and eastward (By = 20 nT). The events occurred in the southern hemisphere flank between 0400 and 0635 local time and at altitudes between 5.6 and 6.2 RE , and were characterized by significantly diminished electron and ion fluxes and a corresponding strong, highly stretched magnetic field. Both spacecraft crossed into the lobe five times with durations from 3-10 minutes. Four of the events were seen by both Van Allen Probes nearly simultaneously despite separations of up to 45 minutes of local time. In all cases the more tailward satellite sees the boundary crossing first. The lobe was also encountered at the same time by the LANL geosynchronous satellites, both at dawn in the northern hemisphere and dusk in the southern hemisphere. These multi-spacecraft observations are used to constrain the spatial and temporal extent of the open/closed field line boundary and to compare this topology to that predicted by a range of magnetic field models. Significant accelerated field aligned oxygen signatures were measured by the HOPE low energy plasma instrument aboard the probes. Using the multi-point measurements we will examine the source of this acceleration and its role in inner magnetosphere ion dynamics.

  19. Multi-point observations of large scale perturbations on the open/closed field line boundary during a geomagnetic storm, as observed by the Van Allen Probes and geostationary satellites

    NASA Astrophysics Data System (ADS)

    Dixon, Patrick

    We discuss a series of lobe entry events observed by the twin Van Allen Probe spacecraft between 0200 and 0515 UTC during the November 14th 2012 geomagnetic storm. During the events Dst was below -100nT with the IMF being strongly southward (Bz = -15nT) and eastward (By = 20 nT). The events occurred in the southern hemisphere flank between 0400 and 0635 local time and at altitudes between 5.6 and 6.2 RE , and were characterized by significantly diminished electron and ion fluxes and a corresponding strong, highly stretched magnetic field. Both spacecraft crossed into the lobe five times with durations from 3-10 minutes. Four of the events were seen by both Van Allen Probes nearly simultaneously despite separations of up to 45 minutes of local time. In all cases the more tailward satellite sees the boundary crossing first. The lobe was also encountered at the same time by the LANL geosynchronous satellites, both at dawn in the northern hemisphere and dusk in the southern hemisphere. These multi-spacecraft observations are used to constrain the spatial and temporal extent of the open/closed field line boundary and to compare this topology to that predicted by a range of magnetic field models. Significant accelerated field aligned oxygen signatures were measured by the HOPE low energy plasma instrument aboard the probes. Using the multi-point measurements we will examine the source of this acceleration and its role in inner magnetosphere ion dynamics.

  20. Multi-point observations of large scale perturbations on the open/closed field line boundary during a geomagnetic storm, as observed by the Van Allen Probes and geostationary satellites

    NASA Astrophysics Data System (ADS)

    Dixon, Paddy; Grande, Manuel; MacDonald, Elizabeth; Skoug, Ruth; Reeves, Geoff; Thomsen, Michelle; Funsten, Herbert; Zou, Shasha; Glocer, Alex; Jia, Xianzhe

    2014-05-01

    We discuss a series of lobe entry events observed by the twin Van Allen Probe spacecraft between 0200 and 0515 UTC during the November 14th 2012 geomagnetic storm. During the events Dst was below -100nT with the IMF being strongly southward (Bz = -15nT) and eastward (By = 20 nT). The events occurred in the southern hemisphere flank between 0400 and 0635 local time and at altitudes between 5.6 and 6.2 RE , and were characterized by significantly diminished electron and ion fluxes and a corresponding strong, highly stretched magnetic field. Both spacecraft crossed into the lobe five times with durations from 3-10 minutes. Four of the events were seen by both Van Allen Probes nearly simultaneously despite separations of up to 45 minutes of local time. In all cases the more tailward satellite sees the boundary crossing first. The lobe was also encountered at the same time by the LANL geosynchronous satellites, both at dawn in the northern hemisphere and dusk in the southern hemisphere. These multi-spacecraft observations are used to constrain the spatial and temporal extent of the open/closed field line boundary and to compare this topology to that predicted by a range of magnetic field models. Significant accelerated field aligned oxygen signatures were measured by the HOPE low energy plasma instrument aboard the probes. Using the multi-point measurements we will examine the source of this acceleration and its role in inner magnetosphere ion dynamics.

  1. The role of growth form and correlated traits in competitive ranking of six perennial ruderal plant species grown in unbalanced mixtures

    NASA Astrophysics Data System (ADS)

    Dietz, Hansjörg; Steinlein, Thomas; Ullmann, Isolde

    1998-02-01

    The competitive abilities of six perennial ruderal plants of three different growth forms were compared via yield measures using an additive diallel experimental design with unbalanced mixtures (9:3 or 3:9 plants per pot, respectively). Thus, in a given mixture species A was grown in two configurations: three individuals in centre position of the pot together with nine plants of species B in border position and vice versa. Effect competitive abilities as well as response competitive abilities of the species were significantly related to canopy height and plant biomass. The species with lower rosette growth form and smaller biomasses were weaker competitors than the species possessing elevated canopies along with higher biomasses, whereas total leaf area was not significantly correlated with competitive ability between species. Species differences in competitive ability were stronger between the plants grown in the central position than between those grown in the border position. Furthermore, interactions between species-specific traits and configuration could be observed, indicating the importance of species proportions and arrangement patterns for evaluation of competitive outcome in the field. The degree of complete transitivity of the competitive network of the six ruderal species, which was significantly higher than expected under the null model in our experimental design, also seemed to depend on species proportions in mixture. Shifts in root:shoot ratio of the centre plants when faced with competition by the border plants were in the direction of higher shoot allocation for the weak competitors with rosette growth form irrespective of the neighbour species, except for Bunias orientalis, which showed a more plastic response. The stronger competitors showed higher root allocation ( Urtica dioica) or were hardly affected at all. Consistent with the results of our experiment, the weaker competitors occur at rather frequently disturbed and therefore transient

  2. Bias extension test on an unbalanced woven composite reinforcement: Experiments and modeling via a second-gradient continuum approach

    NASA Astrophysics Data System (ADS)

    Barbagallo, Gabriele; Madeo, Angela; Azehaf, Ismael; Giorgio, Ivan; Morestin, Fabrice; Boisse, Philippe

    2017-01-01

    The classical continuum models used for the woven fabrics do not fully describe the whole set of phenomena that occur during the testing of those materials. This incompleteness is partially due to the absence of energy terms related to some micro-structural properties of the fabric and, in particular, to the bending stiffness of the yarns. To account for the most fundamental microstructure-related deformation mechanisms occurring in unbalanced interlocks, a second-gradient, hyperelastic, initially orthotropic continuum model is proposed. A constitutive expression for the strain energy density is introduced to account for i) in-plane shear deformations, ii) highly different bending stiffnesses in the warp and weft directions and iii) fictive elongations in the warp and weft directions which eventually describe the relative sliding of the yarns. Numerical simulations which are able to reproduce the experimental behavior of unbalanced carbon interlocks subjected to a Bias Extension Test are presented. In particular, the proposed model captures the macroscopic asymmetric S-shaped deformation of the specimen, as well as the main features of the associated deformation patterns of the yarns at the mesoscopic scale.

  3. Unbalanced activation of glutathione metabolic pathways suggests potential involvement in plant defense against the gall midge Mayetiola destructor in wheat.

    PubMed

    Liu, Xuming; Zhang, Shize; Whitworth, R Jeff; Stuart, Jeffrey J; Chen, Ming-Shun

    2015-01-28

    Glutathione, γ-glutamylcysteinylglycine, exists abundantly in nearly all organisms. Glutathione participates in various physiological processes involved in redox reactions by serving as an electron donor/acceptor. We found that the abundance of total glutathione increased up to 60% in resistant wheat plants within 72 hours following attack by the gall midge Mayetiola destructor, the Hessian fly. The increase in total glutathione abundance, however, is coupled with an unbalanced activation of glutathione metabolic pathways. The activity and transcript abundance of glutathione peroxidases, which convert reduced glutathione (GSH) to oxidized glutathione (GSSG), increased in infested resistant plants. However, the enzymatic activity and transcript abundance of glutathione reductases, which convert GSSG back to GSH, did not change. This unbalanced regulation of the glutathione oxidation/reduction cycle indicates the existence of an alternative pathway to regenerate GSH from GSSG to maintain a stable GSSG/GSH ratio. Our data suggest the possibility that GSSG is transported from cytosol to apoplast to serve as an oxidant for class III peroxidases to generate reactive oxygen species for plant defense against Hessian fly larvae. Our results provide a foundation for elucidating the molecular processes involved in glutathione-mediated plant resistance to Hessian fly and potentially other pests as well.

  4. Block urn design - a new randomization algorithm for sequential trials with two or more treatments and balanced or unbalanced allocation

    PubMed Central

    Zhao, Wenle; Weng, Yanqiu

    2011-01-01

    Permuted block design is the most popular randomization method used in clinical trials, especially for trials with more than two treatments and unbalanced allocation, because of its consistent imbalance control and simplicity in implementation. However, the risk of selection biases caused by high proportion of deterministic assignments is a cause of concern. Efron’s biased coin design and Wei’s urn design provide better allocation randomness without deterministic assignments, but they do not consistently control treatment imbalances. Alternative randomization designs with improved performances have been proposed over the past few decades, including Soares and Wu’s big stick design, which has high allocation randomness, but is limited to two-treatment balanced allocation scenarios only, and Berger’s maximal procedure design which has a high allocation randomness and a potential for more general trial scenarios, but lacks the explicit function for the conditional allocation probability and is more complex to implement than most other designs. The block urn design proposed in this paper combines the advantages of existing randomization designs while overcoming their limitations. Statistical properties of the new algorithm are assessed and compared to currently available designs via analytical and computer simulation approaches. The results suggest that the block urn design simultaneously provides consistent imbalance control and high allocation randomness. It can be easily implemented for sequential clinical trials with two or more treatments and balanced or unbalanced allocation. PMID:21893215

  5. Unbalanced Activation of Glutathione Metabolic Pathways Suggests Potential Involvement in Plant Defense against the Gall Midge Mayetiola destructor in Wheat

    PubMed Central

    Liu, Xuming; Zhang, Shize; Whitworth, R. Jeff; Stuart, Jeffrey J.; Chen, Ming-Shun

    2015-01-01

    Glutathione, γ-glutamylcysteinylglycine, exists abundantly in nearly all organisms. Glutathione participates in various physiological processes involved in redox reactions by serving as an electron donor/acceptor. We found that the abundance of total glutathione increased up to 60% in resistant wheat plants within 72 hours following attack by the gall midge Mayetiola destructor, the Hessian fly. The increase in total glutathione abundance, however, is coupled with an unbalanced activation of glutathione metabolic pathways. The activity and transcript abundance of glutathione peroxidases, which convert reduced glutathione (GSH) to oxidized glutathione (GSSG), increased in infested resistant plants. However, the enzymatic activity and transcript abundance of glutathione reductases, which convert GSSG back to GSH, did not change. This unbalanced regulation of the glutathione oxidation/reduction cycle indicates the existence of an alternative pathway to regenerate GSH from GSSG to maintain a stable GSSG/GSH ratio. Our data suggest the possibility that GSSG is transported from cytosol to apoplast to serve as an oxidant for class III peroxidases to generate reactive oxygen species for plant defense against Hessian fly larvae. Our results provide a foundation for elucidating the molecular processes involved in glutathione-mediated plant resistance to Hessian fly and potentially other pests as well. PMID:25627558

  6. Cytogenetic, molecular and testicular tissue studies in an infertile 45,X male carrying an unbalanced (Y;22) translocation: case report.

    PubMed

    Brisset, S; Izard, V; Misrahi, M; Aboura, A; Madoux, S; Ferlicot, S; Schoevaert, D; Soufir, J C; Frydman, R; Tachdjian, G

    2005-08-01

    (Y;autosome) translocations have been reported in association with male infertility. Different mechanisms have been suggested to explain the male infertility, such as deletion of the azoospermic factor (AZF) on the long arm of the Y chromosome, or meiosis impairment. We describe a new case with a de novo unbalanced translocation t(Y;22) and discuss the genotype-phenotype correlation. A 36 year old male with azoospermia was found to have a mosaic 45,X/46,X, + mar karyotype. Fluorescence in situ hybridization (FISH) showed the presence of a derivative Y chromosome containing the short arm, the centromere and a small proximal part of the long-arm euchromatin of the Y chromosome and the long arm of chromosome 22. The unstable small marker chromosome included the short arm and the centromere of chromosome 22. This unbalanced translocation t(Y;22)(q11.2;q11.1) generated the loss of the long arm of the Y chromosome involving a large part of AZFb, AZFc and Yq heterochromatin regions. Testicular tissue analyses showed sperm in the wet preparation. Our case shows the importance of documenting (Y;autosome) translocations with molecular and testicular tissue analyses.

  7. Balanced vs unbalanced crystalloid resuscitation in a near-fatal model of hemorrhagic shock and the effects on renal oxygenation, oxidative stress, and inflammation.

    PubMed

    Aksu, Ugur; Bezemer, Rick; Yavuz, Berna; Kandil, Asli; Demirci, Cihan; Ince, Can

    2012-06-01

    The aim of the present study was to test the hypothesis that balanced crystalloid resuscitation would be better for the kidney than unbalanced crystalloid resuscitation in a rat hemorrhagic shock model. Male Wistar rats were randomly assigned to four groups (n=6/group): (1) time control; (2) hemorrhagic shock control; (3) hemorrhagic shock followed by unbalanced crystalloid resuscitation (0.9% NaCl); and (4) hemorrhagic shock followed by acetate and gluconate-balanced crystalloid resuscitation (Plasma Lyte). We tested the solutions for their effects on renal hemodynamics and microvascular oxygenation, strong-ion difference, systemic and renal markers of inflammation and oxidative stress including glycocalyx degradation as well as their effects on renal function. The main findings of our study were that: (1) both the balanced and unbalanced crystalloid solutions successfully restored the blood pressure, but renal blood flow was only recovered by the balanced solution although this did not lead to improved renal microvascular oxygenation; (2) while unbalanced crystalloid resuscitation induced hyperchloremia and worsened metabolic acidosis in hemorrhaged rats, balanced crystalloid resuscitation prevented hyperchloremia, restored the acid-base balance, and preserved the anion gap and strong ion difference in these animals; (3) in addition balanced crystalloid resuscitation significantly improved renal oxygen consumption (increased VO(2), decreased [Formula: see text] ); and (4) however neither balanced nor unbalanced crystalloid resuscitation could normalize systemic inflammation or oxidative stress. Functional immunohistochemistry biomarkers showed improvement in L-FABP in favor of balanced solutions in comparison to the hemorrhagic group although no such benefit was seen for renal tubular injury (measured by NGAL) by giving either unbalanced or balanced solutions. Although balanced crystalloid resuscitation seems superior to balanced crystalloid resuscitation in

  8. Window-closing safety system

    DOEpatents

    McEwan, T.E.

    1997-08-26

    A safety device includes a wire loop embedded in the glass of a passenger car window and routed near the closing leading-edge of the window. The wire loop carries microwave pulses around the loop to and from a transceiver with separate output and input ports. An evanescent field only an inch or two in radius is created along the wire loop by the pulses. Just about any object coming within the evanescent field will dramatically reduce the energy of the microwave pulses received back by the transceiver. Such a loss in energy is interpreted as a closing area blockage, and electrical interlocks are provided to halt or reverse a power window motor that is actively trying to close the window. 5 figs.

  9. Window-closing safety system

    DOEpatents

    McEwan, Thomas E.

    1997-01-01

    A safety device includes a wire loop embedded in the glass of a passenger car window and routed near the closing leading-edge of the window. The wire loop carries microwave pulses around the loop to and from a transceiver with separate output and input ports. An evanescent field only and inch or two in radius is created along the wire loop by the pulses. Just about any object coming within the evanescent field will dramatically reduce the energy of the microwave pulses received back by the transceiver. Such a loss in energy is interpreted as a closing area blockage, and electrical interlocks are provided to halt or reverse a power window motor that is actively trying to close the window.

  10. Close Air Support for the Field Army

    DTIC Science & Technology

    1964-05-25

    Cooperation Anzio Training Memorandum Number 7 Cassino The Spring Offensive Fourth Corps Experiment With Horsefly Rover Joe Improvement in Photograohic...EXPERIMENT WITH HORSEFLY In the advance on Rome, 4th Corns had experimented with the use of an airborne controller to dir-ct su-norting planes. On 20... Horsefly systems were to be eventually combined to take alvantage of both a ground and air controller. W’hen all oersonnel became 411bid. 42 Ibid. 92

  11. Evaluation of a three-dimensional MR acoustic radiation force imaging pulse sequence using a novel unbalanced bipolar motion encoding gradient.

    PubMed

    de Bever, Joshua T; Odéen, Henrik; Todd, Nick; Farrer, Alexis I; Parker, Dennis L

    2016-09-01

    MR guided focused ultrasound procedures require accurate focal spot localization in three dimensions. This study presents a three-dimensional (3D) pulse sequence for acoustic radiation force imaging (ARFI) that efficiently localizes the focal spot by means of ultrasound induced tissue displacement over a large field-of-view. A novel unbalanced bipolar motion encoding gradient was implemented to maximize time available for motion encoding, reduce echo times, and allow for longer echo train lengths. Two advanced features, kz reduction factor (KZRF) and kz -level interleaving, were implemented to reduce tissue heating. Studies in gelatin phantoms compared the location of peak displacement and temperature measured by 3D MR thermometry. MR-ARFI induced tissue heating was evaluated through a parametric study of sequence parameters and MR thermometry measurements during repeated application of ARFI sonication patterns. Sequence performance was characterized in the presence of respiration and tissue inhomogeneity. The location of peak displacement and temperature rise agreed within 0.2 ± 0.1 mm and 0.5 ± 0.3 mm in the transverse and longitudinal direction, respectively. The 3D displacement maps were acquired safely, and the KZRF and kz -level interleaving features reduced tissue heating by 51%. High quality displacement maps were obtained despite respiration and tissue inhomogeneities. This sequence provides a safe, accurate, and simple approach to localizing the focal spot in three dimensions with a single scan. Magn Reson Med 76:803-813, 2016. © 2015 Wiley Periodicals, Inc. © 2015 Wiley Periodicals, Inc.

  12. Reanalysis of crystal-field parameters for Nd3+ ions in Nd2BaCuO5 and Nd2BaZnO5 based on standardization, multiple correlated fitting technique, and dataset closeness

    NASA Astrophysics Data System (ADS)

    Rudowicz, Czesław; Gnutek, Paweł; Karbowiak, Mirosław

    2007-09-01

    This paper elucidates some subtle properties of the orthorhombic and monoclinic symmetry crystal-field (CF) Hamiltonians (HCF) , which are not fully understood by some authors. These properties bear on interpretation of experimental data obtained in, e.g., optical spectroscopy, inelastic neutron scattering, and magnetic susceptibility measurements. Our reanalysis of CF parameters (CFPs) is based on application of the standardization idea as well as the idea of dataset closeness. The closeness of any two CFP sets may be represented by the closeness factor C and the norm ratio R=NA/NB for the respective HCF terms: k=2,4,6 , and the global ones Cgl . The specific aims of this paper are twofold. The first aim is to clarify the controversy arising when comparing the standard CF parameters with the nonstandard CFPs. This controversy, originating from the lack of awareness of the standardization applicable to the orthorhombic (as well as monoclinic and triclinic) CFP datasets, is evident, e.g., in the recent study of Nd3+ ion in Nd2BaCuO5 by R. S. Puche [Phys. Rev. B 71, 024403 (2005)]. This leads to an unjustified criticism of the data of other authors. Consideration of standardization and dataset closeness also helps in identifying other inconsistencies concerning R. S. Puche ’s results. The second aim is to determine the alternative physically equivalent CFP datasets generated by the standardization transformation. These CFP datasets are utilized in the multiple correlated fitting technique (MCFT) to improve the reliability of the final fitted CFPs. Additonal refittings of the original energy level data are carried out starting from distinct regions in the parameter space. The independently fitted nonstandard CFPs obtained in this way are then transformed to the standard region and intercorrelated. Our considerations enable us to solve the controversy in question and improve the understanding of the intricacies inherent in the low-symmetry CFP datasets. A comparative

  13. The study of the action of self-friction field on the atom and molecular structures by using combined Hartree-Fock-Roothaan theory for closed and open shells of any symmetry

    NASA Astrophysics Data System (ADS)

    Mamedov, B. A.; Çopuroğlu, E.

    2016-06-01

    In this work, we study the effects of self-friction field on the states of a single configuration of closed and open shells by using the Combined Hartree-Fock-Roothaan equations for atomic-molecular and nuclear systems. Here, we present a program that implements the evaluation of the various properties of atoms and molecular systems with respect to the various values of self-friction quantum numbers. An especially fast and accurate algorithm for the calculation of the self-friction multicenter molecular integrals is obtained by using one-range addition theorems. To demonstrate the action of self-friction field on the atomic and molecular systems we have performed the calculations of H2O, CH3, CH2 and NH3 molecules. For the derivations of the orbital, kinetic and total energies and linear combination coefficients, the results are given for various values of self-friction quantum numbers. For various values of self-friction quantum numbers the obtained results of the orbital, kinetic and total energies and linear combination coefficients have been analyzed.

  14. Commission 42: Close Binary Stars

    NASA Astrophysics Data System (ADS)

    Ribas, Ignasi; Richards, Mercedes T.; Rucinski, Slavek; Bradstreet, David H.; Harmanec, Petr; Kaluzny, Janusz; Mikolajewska, Joanna; Munari, Ulisse; Niarchos, Panagiotis; Olah, Katalin; Pribulla, Theodor; Scarfe, Colin D.; Torres, Guillermo

    2012-04-01

    The present report covers the main developments in the field of close binaries during the triennium 2009-2012. In addition to scientific publications, there have been several opportunities for direct interaction of researchers working on close binaries. A number of meetings focused on more or less specific topics have taken place during this past years but the highlight for Commission 42 is arguably IAU Symposium 282 held in 2011 in Slovakia. The meeting exploited a strong connection in the methodology and tools used by close binary studies and the rapidly advancing field of exoplanet research. After all, exoplanetary systems are mostly discovered and studied using techniques employed by analyses of close binaries for decades. Modelling of exoplanet radial velocity curves and transiting planet light curves are just particular cases of single-lined and eclipsing binary systems, respectively, with very unequal component properties. As shown by IAU Symposium 282, the synergies between the two fields are strong and potentially very useful. Found below is a summary of the main scientific topics and conclusions from this very successful Symposium.

  15. A New Modulation Strategy for Unbalanced Two Phase Induction Motor Drives Using a Three-Leg Voltage Source Inverter

    NASA Astrophysics Data System (ADS)

    Sinthusonthishat, S.; Kinnares, V.

    This paper proposes a new modulation scheme providing unbalanced output terminal voltages of a standard three-leg voltage source inverter (VSI) for unsymmetrical type two-phase induction motors. This strategy allows a control method of the output voltages with typically constant V/Hz for a main winding and with voltage boost to compensate magnitude of current for an auxiliary winding. Harmonic voltage characteristics and the motor performance are investigated under a wide range of operating conditions. Practical verification is presented to confirm correctness and capabilities of the proposed technique. All results are compared to those of a conventional two-leg half bridge topology. The results show that the simulation results well agree with the experimental ones, and also the proposed scheme is superior to the conventional drive.

  16. Detecting mode hopping in single-longitudinal-mode fiber ring lasers based on an unbalanced fiber Michelson interferometer.

    PubMed

    Ma, Mingxiang; Hu, Zhengliang; Xu, Pan; Wang, Wei; Hu, Yongming

    2012-10-20

    A method of detecting mode hopping for single-longitudinal-mode (SLM) fiber ring lasers has been proposed and experimentally demonstrated. The method that is based on an unbalanced Michelson interferometer (MI) utilizing phase generated carrier modulation instantly transforms mode-hopping dynamics into steep phase changes of the interferometer. Multiform mode hops in an SLM erbium-doped fiber ring laser with an 18.6 MHz mode spacing have been detected exactly in real-time domain and discussed in detail. Numerical results show that the MI-based method has a high testing sensitivity for identifying mode hopping, which will play a significant role in evaluating the output stability of SLM fiber lasers.

  17. Effect of unbalanced diets on the long-term metabolism of a toxicant. 1. Lead in rats: preliminary note.

    PubMed

    Baldini, M; Coni, E; Mantovani, A; Stacchini, A; Zanasi, F

    1989-01-01

    The aim of this study was the evaluation of the effect of dietary imbalances on absorption and distribution of lead in the female Sprague-Dawley rat. In this note preliminary results on the relationship between blood concentrations of lead and unbalanced diets are presented. Hyperproteic, hyperglycidic, hyperlipidic and balanced diets were prepared, and most of them included 15 mg/kg lead. Blood samples were collected at day 0, 21, 36, and 95 of the diets and analyzed by anodic stripping voltammetry (ASV). Lead uptake as a function of feed consumption was found to decrease in the order: balanced, hyperproteic and hyperglycidic, hyperlipidic diet. On the other hand lead blood levels were as follows (decreasing order): hyperlipidic, hyperproteic, hyperglycidic, balanced. Further research is being carried out on the influences of dietary imbalances on whole-body distribution of lead.

  18. Improved Power Control Using Optimal Adjustable Coefficients for Three-Phase Photovoltaic Inverter under Unbalanced Grid Voltage

    PubMed Central

    Wang, Qianggang; Zhou, Niancheng; Lou, Xiaoxuan; Chen, Xu

    2014-01-01

    Unbalanced grid faults will lead to several drawbacks in the output power quality of photovoltaic generation (PV) converters, such as power fluctuation, current amplitude swell, and a large quantity of harmonics. The aim of this paper is to propose a flexible AC current generation method by selecting coefficients to overcome these problems in an optimal way. Three coefficients are brought in to tune the output current reference within the required limits of the power quality (the current harmonic distortion, the AC current peak, the power fluctuation, and the DC voltage fluctuation). Through the optimization algorithm, the coefficients can be determined aiming to generate the minimum integrated amplitudes of the active and reactive power references with the constraints of the inverter current and DC voltage fluctuation. Dead-beat controller is utilized to track the optimal current reference in a short period. The method has been verified in PSCAD/EMTDC software. PMID:25243215

  19. Improved power control using optimal adjustable coefficients for three-phase photovoltaic inverter under unbalanced grid voltage.

    PubMed

    Wang, Qianggang; Zhou, Niancheng; Lou, Xiaoxuan; Chen, Xu

    2014-01-01

    Unbalanced grid faults will lead to several drawbacks in the output power quality of photovoltaic generation (PV) converters, such as power fluctuation, current amplitude swell, and a large quantity of harmonics. The aim of this paper is to propose a flexible AC current generation method by selecting coefficients to overcome these problems in an optimal way. Three coefficients are brought in to tune the output current reference within the required limits of the power quality (the current harmonic distortion, the AC current peak, the power fluctuation, and the DC voltage fluctuation). Through the optimization algorithm, the coefficients can be determined aiming to generate the minimum integrated amplitudes of the active and reactive power references with the constraints of the inverter current and DC voltage fluctuation. Dead-beat controller is utilized to track the optimal current reference in a short period. The method has been verified in PSCAD/EMTDC software.

  20. Unique unbalanced X;X translocation (Xq22;p11.2) in a woman with primary amenorrhea but without Ullrich-Turner syndrome

    SciTech Connect

    Letterie, G.S.

    1995-12-04

    This is a report of a patient with delayed puberty and a previously unreported translocation 46,X,-X,+der(X),t(X;X) (q22;p11.2) without any manifestations of Ullrich-Turner syndrome. The relationship of this unbalanced translocation to the critical region hypothesis is discussed. 6 refs., 3 figs.

  1. Rotating-unbalanced-mass devices and methods for scanning balloon-borne-experiments, free-flying spacecraft, and space shuttle/space station attached experiments

    NASA Technical Reports Server (NTRS)

    Polites, Michael E. (Inventor)

    1992-01-01

    A method and apparatus for scanning balloon-borne experiments, free-flying spacecraft, or gimballed experiments mounted on a space shuttle or space station, makes use of one or more rotating unbalanced mass devices for selectively generating circular, line, or raster scan patterns for the experiment line of sight. An auxiliary control system may also be used in combination with the rotating unbalanced mass device, for target acquisition, keeping the scan centered on the target, or for producing complementary motion for raster scanning. The rotating unbalanced mass makes use of a mass associated with a drive shaft, such mass having a center of gravity which is displaced from the drive shaft rotation axis. The drive shaft is driven with a substantially constant angular velocity, thereby resulting in relatively low power requirements since no acceleration or deceleration of the mass is generally involved during steady state operations. The resulting centrifugal force of the rotating unbalanced mass is used to generate desired reaction forces on the experiment or spacecraft to create a desired scan pattern for the experiment line of sight.

  2. Unique unbalanced X;X translocation (Xq22;p11.2) in a woman with primary amenorrhea but without Ullrich-Turner syndrome.

    PubMed

    Letterie, G S

    1995-12-04

    This is a report of a patient with delayed puberty and a previously unreported translocation 46,X -X, +der(X),t(X;X) (q22;p11.2) without any manifestations of Ullrich-Turner syndrome. The relationship of this unbalanced translocation to the critical region hypothesis is discussed.

  3. Closing the loop.

    PubMed

    Dassau, E; Atlas, E; Phillip, M

    2011-02-01

    Closed-loop algorithms can be found in every aspect of everyday modern life. Automation and control are used constantly to provide safety and to improve quality of life. Closed-loop systems and algorithms can be found in home appliances, automobiles, aviation and more. Can one imagine nowadays driving a car without ABS, cruise control or even anti-sliding control? Similar principles of automation and control can be used in the management of diabetes mellitus (DM). The idea of an algorithmic/technological way to control glycaemia is not new and has been researched for more than four decades. However, recent improvements in both glucose-sensing technology and insulin delivery together with advanced control and systems engineering made this dream of an artificial pancreas possible. The artificial pancreas may be the next big step in the treatment of DM since the use of insulin analogues. An artificial pancreas can be described as internal or external devices that use continuous glucose measurements to automatically manage exogenous insulin delivery with or without other hormones in an attempt to restore glucose regulation in individuals with DM using a control algorithm. This device as described can be internal or external; can use different types of control algorithms with bi-hormonal or uni-hormonal design; and can utilise different ways to administer them. The different designs and implementations have transitioned recently from in silico simulations to clinical evaluation stage with practical applications in mind. This may mark the beginning of a new era in diabetes management with the introduction of semi-closed-loop systems that can prevent or minimise nocturnal hypoglycaemia, to hybrid systems that will manage blood glucose (BG) levels with minimal user intervention to finally fully automated systems that will take the user out of the loop. More and more clinical trials will be needed for the artificial pancreas to become a reality but initial encouraging

  4. [A survey on the dietary and health habits according to action styles for unbalanced diets among female university students].

    PubMed

    Nagashima, Kumiko; Sakaguchi, Sanae; Sakaguchi, Takehiro

    2002-05-01

    A survey of woman's students, who had grown up in a time of change-over of Japanese customs regarding food, was conducted to investigate dietary habits, a focus on actions in response to with set needs, The aim was to obtain to measure prospective health maintenance and promotion. The authors carried out a questionnaire for woman's students in 6 universities of Kanto area (a junior college and graduate courses were included) in years 1999 and 2000. In actions regarding the diet, 19.1% of the 815 students responded "I eat everything without fail", 17.7% "I eat almost everything irrespective of likes and dislikes", 24.5% "I strive to eat everything", 19.8% "I leave almost everything I dislike", and 18.5% "I don't eat what I dislike". The students who responded "I leave almost everything I dislike" and "I don't eat what I dislike" had low scores in the questionnaire for dietary and health habits, and they tended to like noodles and popular snacks, and also made frequent use of fast food restaurants. There was not a problem with the majority, but about 30% of the students were judged as confirming an unbalanced diet by this questionnaire. It was found that there were "gaps" and "bad habits" in the regular diet. Moreover, we recognized a tendency to prefer convenience and taste to nutritional balance. This simple questionnaire is suitable for rapid identification of unbalanced distory habits, and both "gaps" and "bad habits" in the regular system diet. It is the most important that we induce students who leave or don't eat what they dislike, to strive to eat everything, irrespective of likes and dislikes.

  5. Variable breakpoints target PAX5 in patients with dicentric chromosomes: a model for the basis of unbalanced translocations in cancer.

    PubMed

    An, Qian; Wright, Sarah L; Konn, Zoë J; Matheson, Elizabeth; Minto, Lynne; Moorman, Anthony V; Parker, Helen; Griffiths, Mike; Ross, Fiona M; Davies, Teresa; Hall, Andy G; Harrison, Christine J; Irving, Julie A; Strefford, Jon C

    2008-11-04

    The search for target genes involved in unbalanced acquired chromosomal abnormalities has been largely unsuccessful, because the breakpoints of these rearrangements are too variable. Here, we use the example of dicentric chromosomes in B cell precursor acute lymphoblastic leukemia to show that, despite this heterogeneity, single genes are targeted through a variety of mechanisms. FISH showed that, although they were heterogeneous, breakpoints on 9p resulted in the partial or complete deletion of PAX5. Molecular copy number counting further delineated the breakpoints and facilitated cloning with long-distance inverse PCR. This approach identified 5 fusion gene partners with PAX5: LOC392027 (7p12.1), SLCO1B3 (12p12), ASXL1 (20q11.1), KIF3B (20q11.21), and C20orf112 (20q11.1). In each predicted fusion protein, the DNA-binding paired domain of PAX5 was present. Using quantitative PCR, we demonstrated that both the deletion and gene fusion events resulted in the same underexpression of PAX5, which extended to the differential expression of the PAX5 target genes, EBF1, ALDH1A1, ATP9A, and FLT3. Further molecular analysis showed deletion and mutation of the homologous PAX5 allele, providing further support for the key role of PAX5. Here, we show that specific gene loci may be the target of heterogeneous translocation breakpoints in human cancer, acting through a variety of mechanisms. This approach indicates an application for the identification of cancer genes in solid tumours, where unbalanced chromosomal rearrangements are particularly prevalent and few genes have been identified. It can be extrapolated that this strategy will reveal that the same mechanisms operate in cancer pathogenesis in general.

  6. School Closings in Philadelphia

    ERIC Educational Resources Information Center

    Jack, James; Sludden, John

    2013-01-01

    In 2012, the School District of Philadelphia closed six schools. In 2013, it closed 24. The closure of 30 schools has occurred amid a financial crisis, headlined by the district's $1.35 billion deficit. School closures are one piece of the district's plan to cut expenditures and close its budget gap. The closures are also intended to make…

  7. First-Trimester Combined Screening Is Effective for the Detection of Unbalanced Chromosomal Translocations at 11 to 12 Weeks of Gestation

    PubMed Central

    Huang, ShangYu; Chang, ChiaLin; Hsiao, ChingHua; Soong, YungKuei; Duan, Tao

    2014-01-01

    The first trimester combined screening, which analyzes fetal nuchal translucency and levels of free β-human chorionic gonadotropin (β-hCG) and pregnancy-associated plasma protein A (PAPP-A) in maternal serum, is routinely used to detect abnormal pregnancies associated with Down syndrome and other trisomy aneuploidies. Based on the hypothesis that major chromosomal translocations could lead to similar biochemical and developmental outcomes during early embryo development, we compared these markers among pregnancies with normal, balanced, or unbalanced fetal karyotypes. Among the parents, 71 (73%) carry balanced reciprocal translocation and 26 (27%) have Robertsonian translocation. Of the 97 pregnancies tested, 39 (40%), 37 (37%), and 22 (23%) fetuses had normal karyotype, balanced chromosomal translocations, and unbalanced chromosomal translocations, respectively. Importantly, we found that pregnancies with an unbalanced translocation had significantly higher free β-hCG multiple of the median (MoM) and larger nuchal translucency thickness than those with normal karyotype or balanced translocations. Analysis showed that the area under a receiver operating characteristic curve (AUC) is 0.716, 0.820, and 0.936 for free β-hCG MoM, PAPP-A MoM, and fetal nuchal translucency, respectively. When these 3 independent factors were combined, the AUC reached 0.976. In addition, logistic regression showed that the most optimal model for predicting an unbalanced chromosomal translocation is a combination of PAPP-A and nuchal translucency with an AUC of 0.980. Therefore, the first trimester combined screening is not only effective in the screening of Down syndrome and other trisomy abnormalities but also has high sensitivity for the detection of unbalanced chromosomal translocations in fetuses. PMID:24177714

  8. The accuracy of using the spectral width boundary measured in off-meridional SuperDARN HF radar beams as a proxy for the open-closed field line boundary

    NASA Astrophysics Data System (ADS)

    Chisham, G.; Freeman, M. P.; Sotirelis, T.; Greenwald, R. A.

    2005-10-01

    Determining reliable proxies for the ionospheric signature of the open-closed field line boundary (OCB) is crucial for making accurate measurements of magnetic reconnection. This study compares the latitudes of spectral width boundaries (SWBs) measured by different beams of the Goose Bay radar of the Super Dual Auroral Radar Network (SuperDARN), with the latitudes of OCBs determined using the low-altitude Defense Meteorological Satellite Program (DMSP) spacecraft, in order to determine whether the accuracy of the SWB as a proxy for the ionospheric projection of the OCB depends on the line-of-sight direction of the radar beam. The latitudes of SWBs and OCBs were identified using automated algorithms applied to 5 years (1997 2001) of data measured in the 1000 1400 magnetic local time (MLT) range. Six different Goose Bay radar beams were used, ranging from those aligned in the geomagnetic meridional direction to those aligned in an almost zonal direction. The results show that the SWB is a good proxy for the OCB in near-meridionally-aligned beams but becomes progressively more unreliable for beams greater than 4 beams away from the meridional direction. We propose that SWBs are identified at latitudes lower than the OCB in the off-meridional beams due to the presence of high spectral width values that result from changes in the orientation of the beams with respect to the gradient in the large-scale ionospheric convection pattern. Keywords. Ionosphere (Instruments and techniques; Plasma convection) Magnetospheric physics (Magnetopause, cusp and boundary layers)

  9. Use of geostatistic techniques to describe a reservoir to be submitted into a secondary recovery process field case: {open_quotes}Eocene B-Inferior/VLG-3659, Ceuta, Venezuela{close_quotes}

    SciTech Connect

    Hernandez, T.; Poquioma, W.

    1997-08-01

    This study presents the results of an integrated reservoir study of the Eocene B-Inferior/VLG-3659, Area 7, Ceuta filed. This field located in the Maracaibo Lake in the western side of Venezuela. The objective was to evaluating the feasibility to implement a secondary recovery project by means of water flooding. Core information was used for this study (194 ft), PVT analysis, RFI, build-up and statistic`s pressure analysis, modem logs and production history data. Using geostatistical techniques (Kriging) it was defined a low uncertainty geological model that was validated by means of a black oil simulator (Eclipse). The results showed a good comparison of historical pressure of the reservoir against those obtained from the model, without the need of {open_quotes}history matching{close_quotes}. It means without modifying neither the initial rock properties nor reservoir fluids. The results of this study recommended drilling in two new locations, also the reactivation of four producing wells and water flooding under peripherical array by means of four injection wells, with the recovery of an additional 30.2 MMSTB. The economical evaluation shows an internal return rate of 31.4%.

  10. Population genetics and a study of speciation using next-generation sequencing: an educational primer for use with "Patterns of transcriptome divergence in the male accessory gland of two closely related species of field crickets".

    PubMed

    Wittkopp, Patricia J

    2013-03-01

    Understanding evidence for the genetic basis of reproductive isolation is imperative for supporting students' understanding of mechanisms of speciation in courses such as Genetics and Evolutionary Biology. An article by Andrés et al. in the February 2013 issue of GENETICS illustrates how advances in DNA sequencing are accelerating studies of population genetics in species with limited genetic and genomic resources. Andrés et al. use the latest sequencing technologies to systematically identify and characterize sites in the DNA that vary within, and have diverged between, species to explore speciation in crickets. This primer, coupled with that article, will help instructors introduce and reinforce important concepts in genetics and evolution while simultaneously introducing modern methodology in the undergraduate classroom. Related article in Andrés, J. A., E. L. Larson, S. M. Bogdanowicz, and R. G. Harrison, 2013 Patterns of transcriptome divergence in the male accessory gland of two closely related species of field crickets. Genetics 193: 501-513.

  11. Space charge, plasma potential and electric field distributions in HiPIMS discharges of varying configuration

    NASA Astrophysics Data System (ADS)

    Liebig, B.; Bradley, J. W.

    2013-08-01

    An electron-emitting (emissive) probe has been used to study the temporal and spatial distribution of the plasma potential during high-power impulse magnetron sputtering (HiPIMS) discharges with various substrate and magnetic field configurations. The average power was 700 W, with a repetition frequency of 100 Hz and pulse duration of 100 µs. Strongly negative plasma potentials exceeding -300 V and electric fields up to 10 kV m-1, caused by strong separation of charges with net charge carrier densities Δn of about 1014 m-3, were observed during the ignition of the discharge. The spatial distribution of the plasma potential in the stable stage of the discharge showed values consistently 5 V more negative for a floating substrate compared with a grounded one, so enhancing electron transport around the insulated substrate to grounded walls. However, this change in the electrical configuration of the plasma does not alter significantly the fraction of ionized sputtered particles (of about 30%) that can potentially reach the substrate. By changing the degree of unbalance of the sputtering source, we find a strong correlation between the electric field strength in the magnetic trap (created through charge separation) and the absolute value (and shape) of the magnetic field. For the more unbalanced magnetron, a flattening of the plasma potential structure (decrease in the axial electric field) was observed close to the target. Our findings show in principle that manipulation of the potential barrier close to the target through changing the magnetic field can regulate the proportion of sputtered and ionized species reaching the substrate.

  12. Unbalanced interchromosomal insertion diagnosed prenatally by FISH, with carrier mother, previously misdiagnosed as having a balanced reciprocal translocation

    SciTech Connect

    Yu, M.T.; Leiber, E.; Qazi, Q.

    1994-09-01

    Insertion translocations are rare. A carrier with a balanced insertion translocation is most likely to be detected through offspring with an unbalanced translocation. We with to report a case where a correct diagnosis, made prenatally with FISH, corrected the initial misdiagnosis of the mother in another institute. PDL received an amniotic fluid sample from a 28 y.o. woman (G5P2Sab1TOP1) at 19 wks gestation. The indications were a reported balanced translocation, t(6;13), in the mother and a previous daughter with an unbalanced translocation. Chromosome analysis of the amniocytes showed a female karyotype with an abnormal chr. 13. Since the mother was diagnosed as having t(6;13)(q21;q34), the der(13) in the amniocytes was initially assumed to result from an adjacent segregation of the t(6;13). However, the banding patterns of this abnormal chr. 13 did not fit into the above defined translocation. With FISH and a chr. 13 painting probe, this der(13) was painted in the proximal and the distal thirds, but NOT in the middle region. This indicates that the middle section of the der(13) must have originated from 6q. The banding pattern is compatible with a direct insertion of 6q15 to 6q23.3 into 13q21.2. Thus, the fetus has partial trisomy 6q. After counseling, the mother elected to terminate the pregnancy but later changed her mind. An 8 lb 12 oz baby girl was born at 36 wks. (mother diabetic). Chromosome analysis of the newborn blood confirmed the dx. The mother was studied, using multicolor painting probes for chromosomes 13 and 6, a balanced direct insertion of 6q15 to 6q23.3 into chr. 13q21.2 was clearly shown. The previous affected daughter with a 13q+ is now 4 y.o. (a restudy is planned). She has microcephaly, severe developmental delay and other dysmorphic features. This case illustrates the advantage of using FISH to arrive at a definitive diagnosis of an insertion translocation.

  13. Closing the Advising Session.

    ERIC Educational Resources Information Center

    Jeon, Mihyon

    2003-01-01

    This study investigates closing patterns for an institutional conversation in an ELP (English Language Program) at a university in the United States, noting the relationship between the closing patterns of the participants and their level of proficiency in English. By indicating that ESL learners, especially beginners, face difficulty in closing…

  14. Surviving a School Closing

    ERIC Educational Resources Information Center

    De Witt, Peter M.; Moccia, Josephine

    2011-01-01

    When a beloved school closes, community emotions run high. De Witt and Moccia, administrators in the Averill Park School District in upstate New York, describe how their district navigated through parents' anger and practical matters in closing a small neighborhood elementary school and transferring all its students to another school. With a group…

  15. Familial translocation resulting in Wolf-Hirschhorn syndrome in two related unbalanced individuals: Clinical evaluation of a 39-year-old man with Wolf-Hirschhorn syndrome

    SciTech Connect

    Wheeler, P.G.; Weaver, D.D.; Palmer, C.G.

    1995-02-13

    A chromosomal translocation between chromosomes 4 and 8 resulting in Wolf-Hirschhorn syndrome in 2 individuals has been traced through 4 generations of a family. Ascertainment of the family was through a newborn infant with evident Wolf-Hirschhorn syndrome who had an unbalanced chromosomal translocation (46,XY,-4,+der(4),t(4;8) (p15.32;p22)). Discussion with the family documented a paternal great-uncle who also had a similar phenotype and profound mental retardation. Subsequently this individual was found to have the same unbalanced chromosome constitution as the propositus. The 39-year-old great-uncle is the oldest reported individual with the Wolf-Hirschhorn syndrome. The importance of chromosome evaluation of older individuals with mental retardation syndromes is emphasized. 4 refs., 6 figs.

  16. Thickness Effects of TiC Interlayer on Tribological Properties of Diamond-Like Carbon Prepared by Unbalanced Magnetron Sputtering Method.

    PubMed

    Park, Chulmin; Lee, Jaehyeong; Park, Yong Seob

    2015-11-01

    We investigated the tribological properties of diamond-like carbon (DLC) films prepared with TiC interlayer of various thicknesses as the adhesive layer. DLC and TiC thin films were prepared using unbalanced magnetron (UBM) sputtering method using graphite and titanium as targets. TiC films as the interlayer were deposited under DLC films and various physical, tribological, and structural properties of the films fabricated with various TiC interlayer thicknesses were investigated. With various TiC interlayer thicknesses under DLC films, the tribological properties of films were improved with increasing thickness and the DLC/TiC layer fabricated by unbalanced magnetron sputtering method are exhibited maximum high hardness over 27 GPa and high elastic modulus over 242 GPa, and a smooth surface below 0.09 nm.

  17. Second Tumor Induction Risk in IMRT for Prostate Cancer: An Unbalanced Comparison Between Surgery and Radiotherapy?

    PubMed

    Calandrino, Riccardo; Perna, Lucia; Belli, Maria Luisa; Botti, Andrea; Cattaneo, Mauro; Fiorino, Claudio; Cozzarini, Cesare; Iori, Mauro

    2015-12-01

    The aim of this study was to evaluate the risk of second tumor induction for prostate patients treated with volumetric modulated arc therapy in age classes 50-70. Based on both age-dependent models and doses to critical organs, the risk of second tumor induction was evaluated simulating the small field (prostate and seminal vesicles) and large field (whole pelvis) for Helical Tomotherapy and Rapid Arc. The doses to the organs closest to the treatment volume were derived from treatment planning system data. Whereas, due to the lack of calculation algorithms where leakage and internal radiation scattering are unreliable at a large distance from target, the doses to the organs outside the treatment volume were measured in an anthropomorphic phantom. Doses from Image Guided Radiotherapy (IGRT) were also assessed on phantom measurements. The Lifetime Attributable Risk (LAR) for second tumor induction increases from 2.2 to 13.7% as irradiated volume increases and age decreases. IGRT could add a non-negligible factor to the risk when daily set-up verification with high-resolution modality is included. As prostate cancer is detected earlier, the probability of an increase in early stage patients rises, and life expectancy thus increases. Radiotherapy has improved its capability in the tailoring of the dose around the target at the cost of a greater dose to surrounding organs, thus increasing the risk of second tumor induction, especially for those patients expected to survive 15 y or more.

  18. Corrosion resistance of zirconium oxynitride coatings deposited via DC unbalanced magnetron sputtering and spray pyrolysis-nitriding

    NASA Astrophysics Data System (ADS)

    Cubillos, G. I.; Bethencourt, M.; Olaya, J. J.

    2015-02-01

    ZrOxNy/ZrO2 thin films were deposited on stainless steel using two different methods: ultrasonic spray pyrolysis-nitriding (SPY-N) and the DC unbalanced magnetron sputtering technique (UBMS). Using the first method, ZrO2 was initially deposited and subsequently nitrided in an anhydrous ammonia atmosphere at 1023 K at atmospheric pressure. For UBMS, the film was deposited in an atmosphere of air/argon with a Φair/ΦAr flow ratio of 3.0. Structural analysis was carried out through X-ray diffraction (XRD), and morphological analysis was done through scanning electron microscopy (SEM) and atomic force microscopy (AFM). Chemical analysis was carried out using X-ray photoelectron spectroscopy (XPS). ZrOxNy rhombohedral polycrystalline film was produced with spray pyrolysis-nitriding, whereas using the UBMS technique, the oxynitride films grew with cubic Zr2ON2 crystalline structures preferentially oriented along the (2 2 2) plane. Upon chemical analysis of the surface, the coatings exhibited spectral lines of Zr3d, O1s, and N1s, characteristic of zirconium oxynitride/zirconia. SEM analysis showed the homogeneity of the films, and AFM showed morphological differences according to the deposition technique of the coatings. Zirconium oxynitride films enhanced the stainless steel's resistance to corrosion using both techniques. The protective efficacy was evaluated using electrochemical techniques based on linear polarization (LP). The results indicated that the layers provide good resistance to corrosion when exposed to chloride-containing media.

  19. Lack of myotubularin (MTM1) leads to muscle hypotrophy through unbalanced regulation of the autophagy and ubiquitin-proteasome pathways.

    PubMed

    Al-Qusairi, Lama; Prokic, Ivana; Amoasii, Leonela; Kretz, Christine; Messaddeq, Nadia; Mandel, Jean-Louis; Laporte, Jocelyn

    2013-08-01

    Mutations in the phosphoinositide phosphatase myotubularin (MTM1) results in X-linked myotubular/centronuclear myopathy (XLMTM), characterized by a severe decrease in muscle mass and strength in patients and murine models. However, the molecular mechanism involved in the muscle hypotrophy is unclear. Here we show that the IGF1R/Akt pathway is affected in Mtm1-deficient murine muscles, characterized by an increase in IGF1 receptor and Akt levels in both the presymptomatic and symptomatic phases. Moreover, up-regulation of atrogenes was observed in the presymptomatic phase of the myopathy, supporting overactivation of the ubiquitin-proteasome pathway. In parallel, the autophagy machinery was affected as indicated by the increase in the number of autophagosomes and of autophagy markers, such as LC3 and P62. However, phosphorylation of FOXO3a and mTOR were abnormal at late but not at early stages of the disease, suggesting that myotubularin acts both upstream in the IGF1R/Akt pathway and downstream on the balance between the autophagy and ubiquitin-proteasome pathways in vivo. Adeno-associated virus-mediated delivery of Mtm1 into Mtm1-null muscles rescued muscle mass and normalized the expression levels of IGF1 receptor, the ubiquitin-proteasome pathway, and autophagy markers. These data support the hypothesis that the unbalanced regulation of the ubiquitin proteasome pathway and the autophagy machinery is a primary cause of the XLMTM pathogenesis.

  20. Practical quantum private query of blocks based on unbalanced-state Bennett-Brassard-1984 quantum-key-distribution protocol

    PubMed Central

    Wei, Chun-Yan; Gao, Fei; Wen, Qiao-Yan; Wang, Tian-Yin

    2014-01-01

    Until now, the only kind of practical quantum private query (QPQ), quantum-key-distribution (QKD)-based QPQ, focuses on the retrieval of a single bit. In fact, meaningful message is generally composed of multiple adjacent bits (i.e., a multi-bit block). To obtain a message from database, the user Alice has to query l times to get each ai. In this condition, the server Bob could gain Alice's privacy once he obtains the address she queried in any of the l queries, since each ai contributes to the message Alice retrieves. Apparently, the longer the retrieved message is, the worse the user privacy becomes. To solve this problem, via an unbalanced-state technique and based on a variant of multi-level BB84 protocol, we present a protocol for QPQ of blocks, which allows the user to retrieve a multi-bit block from database in one query. Our protocol is somewhat like the high-dimension version of the first QKD-based QPQ protocol proposed by Jacobi et al., but some nontrivial modifications are necessary. PMID:25518810

  1. Allocation of Capacitors and Voltage Regulators in Unbalanced Distribution Systems: A Multi-objective Problem in Probabilistic Frameworks

    NASA Astrophysics Data System (ADS)

    Carpinelli, Guido; Noce, Christian; Russo, Angela; Varilone, Pietro

    2014-12-01

    Capacitors and series voltage regulators are used extensively in distribution systems to reduce power losses and improve the voltage profile along the feeders. This paper deals with the problem of contemporaneously choosing optimal locations and sizes for both capacitors and series voltage regulators in three-phase, unbalanced distribution systems. This is a mixed, non-linear, constrained, multi-objective optimization problem that usually is solved in deterministic scenarios. However, distribution systems are stochastic in nature, which can lead to inaccurate deterministic solutions. To take into account the unavoidable uncertainties that affect the input data related to the problem, in this paper, we have formulated and solved the multi-objective optimization problem in probabilistic scenarios. To address the multi-objective optimization problem, algorithms were used in which all the objective functions were combined to form a single function. These algorithms allow us to transform the original multi-objective optimization problem into an equivalent, single-objective, optimization problem, an approach that appeared to be particularly suitable since computational time was an important issue. To further reduce the computational efforts, a linearized form of the equality constraints of the optimization model was used, and a micro-genetic algorithm-based procedure was applied in the solution method.

  2. Illumination effects on the ferroelectric properties of zinc oxide films grown by DC-unbalanced magnetron sputtering

    NASA Astrophysics Data System (ADS)

    Kurniawan, R.; Willy, F.; Nurfani, E.; Muhammady, S.; Sutjahja, I. M.; Winata, T.; Darma, Y.

    2017-02-01

    We study the illumination effect on the ferroelectric properties of zinc oxide (ZnO) film grown by DC-unbalanced magnetron sputtering. We focus on the P–E hysteresis response of the as-grown ZnO (ag-ZnO) and annealed-ZnO (ann-ZnO) films under dark and light conditions. The measurement of ferroelectric properties is performed by driving a positive voltage on the top-side of the films. Under the dark condition, a strong P–E response is observable on the ann-ZnO film due to the structural enhancement. The value of electrical coercivity for ferroelectric polarization is strongly related to the light illumination. The illumination treatment changed the P–E hysteresis of the ZnO films from symmetric to asymmetric. We found that higher energy illumination promotes a higher electric coercivity. These results confirmed that ferroelectric properties could be effectively tailored by tuning the energy of the light source. This interrelated electrical and optical properties is an important phenomenon to design a new light-induced non-volatile device application.

  3. The dynamic behavior of a cantilever beam coupled to a non-ideal unbalanced motor through numerical and experimental analysis

    NASA Astrophysics Data System (ADS)

    Gonçalves, P. J. P.; Silveira, M.; Pontes Junior, B. R.; Balthazar, J. M.

    2014-09-01

    An excitation force that is not influenced by the system state is said to be an ideal energy source. In real situations, a direct and feedback coupling between the excitation source and the system must always exist at a certain level. This manifestation of the law of conservation of energy is known as the Sommerfeld effect. In the case of obtaining a mathematical model for such a system, additional equations are usually necessary to describe the vibration sources with limited power and its coupling with the mechanical system. In this work, a cantilever beam and a non-ideal DC motor fixed to its free end are analyzed. The motor has an unbalanced mass that provides excitation to the system which is proportional to the current applied to the motor. During the coast up operation of the motor, if the drive power is increased slowly, making the excitation frequency pass through the first natural frequency of the beam, the DC motor speed will remain the same until it suddenly jumps to a much higher value (simultaneously its amplitude jumps to a much lower value) upon exceeding a critical input power. It was found that the Sommerfeld effect depends on some system parameters and the motor operational procedures. These parameters are explored to avoid the resonance capture in the Sommerfeld effect. Numerical simulations and experimental tests are used to help gather insight of this dynamic behavior.

  4. Association of affect with vertical position in L1 but not in L2 in unbalanced bilinguals

    PubMed Central

    Li, Degao; Liu, Haitao; Ma, Bosen

    2015-01-01

    After judging the valence of the positive (e.g., happy) and the negative words (e.g., sad), the participants' response to the letter (q or p) was faster and slower, respectively, when the letter appeared at the upper end than at the lower end of the screen in Meier and Robinson's (2004) second experiment. To compare this metaphorical association of affect with vertical position in Chinese-English bilinguals' first language (L1) and second language (L2) (language), we conducted four experiments in an affective priming task. The targets were one set of positive or negative words (valence), which were shown vertically above or below the center of the screen (position). The primes, presented at the center of the screen, were affective words that were semantically related to the targets, affective words that were not semantically related to the targets, affective icon-pictures, and neutral strings in Experiment 1–4, respectively. In judging the targets' valence, the participants showed different patterns of interactions between language, valence, and position in reaction times across the experiments. We concluded that metaphorical association between affect and vertical position works in L1 but not in L2 for unbalanced bilinguals. PMID:26074847

  5. Caspase 3 activation and PARP cleavage in lymphocytes from newborn babies of diabetic mothers with unbalanced glycaemic control.

    PubMed

    Tarquini, F; Tiribuzi, R; Crispoltoni, L; Porcellati, S; Del Pino, A M; Orlacchio, A; Coata, G; Arnone, S; Torlone, E; Cappuccini, B; Di Renzo, G C; Orlacchio, A

    2014-01-01

    Several epidemiological studies showed that gestational diabetes mellitus is the most frequent metabolic disorder of pregnancy, the pathogenesis of which has yet to be completely clarified. The aim of this study was to investigate the presence and processing of caspase 3 (Casp3) and poly(ADP-ribose) polymerase 1 (PARP1) in cord blood lymphocytes as markers of apoptosis in relation to glycaemic control during intrauterine life. Our results showed a specific positive correlation between the levels of active Casp3 (17-19 kDa) and the inactive form of PARP1 (89 kDa) in lymphocytes isolated from newborn babies of diabetic women with unbalanced glycaemic control, with a direct correlation between the activation of casp3 and the inactivation of PARP1, that makes lymphocytes unresponsive towards lipopolysaccharide stimulation, highlighting an altered functional response. Besides more studies are required to fully correlate the activation of the apoptotic process during the intrauterine life with the foetal health later in life, our study indicates that a cord blood lymphocyte, an easily accessible source, is informative about the activation of apoptotic stimuli in circulating cells of newborn babies in relation to the glycaemic control reached by the mother during pregnancy.

  6. Structure and mechanical properties of Ti-Si-N films deposited by combined DC/RF reactive unbalanced magnetron sputtering

    NASA Astrophysics Data System (ADS)

    Ding, X. Z.; Zeng, X. T.; Liu, Y. C.; Yang, Q.; Zhao, L. R.

    2004-11-01

    Ti-Si-N nanocomposite films with Si content between 0 and 13.5 at. % were deposited by combined DC/RF reactive unbalanced magnetron sputtering. The composition, structure, and mechanical properties of the as-deposited Ti-Si-N films were measured by energy dispersive analysis of x rays, x-ray diffraction (XRD), and nanoindentation experiments, respectively. All of the Ti-Si-N films exhibited a higher hardness than pure TiN films deposited under similar conditions. The highest hardness (~41 GPa) was obtained in the film with Si content of about 8 at. %. Ti-Si-N films also exhibited a higher resistance to plastic deformation (i.e., higher ratio H3/E*2) than pure TiN. XRD patterns revealed that the as-deposited films were composed of cubic TiN crystallites with a preferential orientation of (111). With increase of RF power applied to the Si targets, the TiN (111) peak intensity or TiN crystallite size increased in the lower RF power range but decreased in the higher RF power range, showing a maximum at an RF power of 500 W (power density ~1.14 W/cm2), corresponding to a Si content of about 5 at. % in the film.

  7. Time dependence of carbon film deposition on SnO{sub 2}/Si using DC unbalanced magnetron sputtering

    SciTech Connect

    Alfiadi, H. Aji, A. S. Darma, Y.

    2014-02-24

    Carbon deposition on SnO{sub 2} layer has been demonstrated at low temperature using DC unbalanced magnetron-sputtering technique for various time depositions. Before carbon sputtering process, SnO{sub 2} thin layer is grown on silicon substrate by thermal evaporation method using high purity Sn wire and then fully oxidizes by dry O{sub 2} at 225°C. Carbon sputtering process was carried out at pressure of 4.6×10{sup −2} Torr by keeping the substrate temperature of 300 °C for sputtering deposition time of 1 to 4 hours. The properties of SnO{sub 2}/Si structure and carbon thin film on SnO{sub 2} is characterized using SEM, EDAX, XRD, FTIR, and Raman Spectra. SEM images and XRD spectra show that SnO2 thin film has uniformly growth on Si substrate and affected by annealing temperature. Raman and FTIR results confirm the formation of carbon-rich thin film on SnO{sub 2}. In addition, XRD spectra indicate that some structural change occur by increasing sputtering deposition time. Furthermore, the change of atomic structure due to the thermal annealing is analized by XRD spectra and Raman spectroscopy.

  8. Experimental Investigation of the Interface Behavior of Balanced and Unbalanced E-Glass/Polyester Woven Fabric Composite Laminates

    NASA Astrophysics Data System (ADS)

    Triki, E.; Zouari, B.; Jarraya, A.; Dammak, F.

    2013-12-01

    The aim of this work is to study the influence of weave structure on the crack growth behavior of thick E-glass/polyester woven fabric composites laminates. Two different types of laminates were fabricated: (i) balanced: plain weave (taffetas T)/chopped strand mat weave (M) [T/M]6 and (ii) unbalanced: 4-hardness satin weave (S)/chopped strand mat weave [S/M]7. In order to accurately predict damage criticality in such structures, mixed mode fracture toughness data is required. So, the experiments were conducted using standards delamination tests under mixed mode loading and pure mode loading. These tests were carried out in mode II using End Load Split (ELS) tests and in mixed-mode I+II by Mixed Mode Flexure (MMF) tests under static conditions. The test methodology used for the experiments will be presented. The experimental results have been expressed in terms of total strain energy release rate and R-curves. The fracture toughness results show that the T/M interface is more resistant to delamination than the S/M interface.

  9. Noncommutative via closed star product

    NASA Astrophysics Data System (ADS)

    Kupriyanov, V. G.; Vitale, P.

    2015-08-01

    We consider linear star products on of Lie algebra type. First we derive the closed formula for the polydifferential representation of the corresponding Lie algebra generators. Using this representation we define the Weyl star product on the dual of the Lie algebra. Then we construct a gauge operator relating the Weyl star product with the one which is closed with respect to some trace functional, Tr ( f ⋆ g) = Tr ( f · g). We introduce the derivative operator on the algebra of the closed star product and show that the corresponding Leibniz rule holds true up to a total derivative. As a particular example we study the space R {/θ 3} with type noncommutativity and show that in this case the closed star product is the one obtained from the Duflo quantization map. As a result a Laplacian can be defined such that its commutative limit reproduces the ordinary commutative one. The deformed Leibniz rule is applied to scalar field theory to derive conservation laws and the corresponding noncommutative currents.

  10. Average Fade Duration of Dual Selection Diversity over Correlated Unbalanced Nakagami-m Fading Channels in the Presence of Cochannel Interference

    NASA Astrophysics Data System (ADS)

    Panajotović, Aleksandra; Sekulović, Nikola; Drača, Dragan; Stefanović, Mihajlo; Stefanović, Časlav

    2013-12-01

    A dual selection combining (SC) receiver with correlated and unbalanced diversity branches operating in interference-limited Nakagami-m fading environment is considered in this paper. Actually, average fade duration (AFD) of SC system applying desired signal decision algorithm is obtained. Numerical results can be used to examine the effects of fading severity, input signal-to-interference ratio (SIR) unbalance and level of branch correlation on the AFD, as well as the correctness of proposed analytical formulation.

  11. An improved synchronous reference frame current control strategy for a photovoltaic grid-connected inverter under unbalanced and nonlinear load conditions.

    PubMed

    Naderipour, Amirreza; Asuhaimi Mohd Zin, Abdullah; Bin Habibuddin, Mohd Hafiz; Miveh, Mohammad Reza; Guerrero, Josep M

    2017-01-01

    In recent years, renewable energy sources have been considered the most encouraging resources for grid and off-grid power generation. This paper presents an improved current control strategy for a three-phase photovoltaic grid-connected inverter (GCI) under unbalanced and nonlinear load conditions. It is challenging to suppress the harmonic content in the output current below a pre-set value in the GCI. It is also difficult to compensate for unbalanced loads even when the grid is under disruption due to total harmonic distortion (THD) and unbalanced loads. The primary advantage and objective of this method is to effectively compensate for the harmonic current content of the grid current and microgrid without the use of any compensation devices, such as active and passive filters. This method leads to a very low THD in both the GCI currents and the current exchanged with the grid. The control approach is designed to control the active and reactive power and harmonic current compensation, and it also corrects the system unbalance. The proposed control method features the synchronous reference frame (SRF) method. Simulation results are presented to demonstrate the effective performance of the proposed method.

  12. An improved synchronous reference frame current control strategy for a photovoltaic grid-connected inverter under unbalanced and nonlinear load conditions

    PubMed Central

    Naderipour, Amirreza; Asuhaimi Mohd Zin, Abdullah; Bin Habibuddin, Mohd Hafiz; Miveh, Mohammad Reza; Guerrero, Josep M.

    2017-01-01

    In recent years, renewable energy sources have been considered the most encouraging resources for grid and off-grid power generation. This paper presents an improved current control strategy for a three-phase photovoltaic grid-connected inverter (GCI) under unbalanced and nonlinear load conditions. It is challenging to suppress the harmonic content in the output current below a pre-set value in the GCI. It is also difficult to compensate for unbalanced loads even when the grid is under disruption due to total harmonic distortion (THD) and unbalanced loads. The primary advantage and objective of this method is to effectively compensate for the harmonic current content of the grid current and microgrid without the use of any compensation devices, such as active and passive filters. This method leads to a very low THD in both the GCI currents and the current exchanged with the grid. The control approach is designed to control the active and reactive power and harmonic current compensation, and it also corrects the system unbalance. The proposed control method features the synchronous reference frame (SRF) method. Simulation results are presented to demonstrate the effective performance of the proposed method. PMID:28192436

  13. Novel Unbalanced Translocations Affecting the Long Arms of Chromosomes 10 and 22 Cause Complex Syndromes with Very Severe Neurodevelopmental Delay, Speech Impairment, Autistic Behavior, and Epilepsy.

    PubMed

    Coci, Emanuele G; Auhuber, Andrea; Langenbach, Anna; Mrasek, Kristin; Riedel, Joachim; Leenen, Andreas; Lücke, Thomas; Liehr, Thomas

    2017-01-01

    Isolated abnormalities in terminal regions of chromosomes 10q and 22q were formerly described in patients affected by neuropsychological impairment, abnormal facies, and heterogeneous structural abnormalities of the body. Chromosomes 10q and 22q harbor important genes that play a major role in CNS development, like DOCK1 and SHANK3, and in overall body growth, like FGFR2 and HTRA1. By using clinical, neuroradiological, neurophysiological, and genetic assessment, we studied 3 siblings affected by 2 different forms of very severe neuropsychological impairment with structural physical abnormalities, epilepsy, and body overgrowth. The genetic analysis revealed 2 different unbalanced translocations t(10;22)(q26.13;q13.32) of genetic material between the long arms of chromosomes 10 and 22, deriving from a maternal balanced translocation. Consequences of the unbalanced translocation were the simultaneous partial monosomy of 10q26.13 to 10qter and partial trisomy of 22q13.32 to 22qter in 2 patients and the simultaneous trisomy distal q10 and monosomy distal q22 in 1 patient, respectively. To the best of our knowledge, we here describe for the first time a causal association between an unbalanced translocation t(10;22) affecting the long arms of both chromosomes 10 and 22 and a very severe neurodevelopmental delay in 3 siblings. © 2017 S. Karger AG, Basel.

  14. Uncritical and unbalanced coverage of synthetic biology in the Nordic press.

    PubMed

    Ancillotti, Mirko; Holmberg, Niklas; Lindfelt, Mikael; Eriksson, Stefan

    2017-02-01

    Synthetic biology will probably have a high impact on a variety of fields, such as healthcare, environment, biofuels, agriculture, and so on. A driving theme in European research policy is the importance of maintaining public legitimacy and support. Media can influence public attitudes and are therefore an important object of study. Through qualitative content analysis, this study investigates the press coverage of synthetic biology in the major Nordic countries between 2009 and 2014. The press coverage was found to be event-driven and there were striking similarities between countries when it comes to framing, language use, and treated themes. Reporters showed a marked dependence on their sources, mainly scientists and stakeholders, who thus drives the media agenda. The media portrayal was very positive, with an optimistic look at future benefits and very little discussion of possible risks.

  15. Closing in on Ceres

    NASA Image and Video Library

    2013-12-03

    NASA Dawn spacecraft will be getting an up-close look at the dwarf planet Ceres starting in late March or the beginning of April 2015. This graphic shows the science-gathering orbits planned for the spacecraft.

  16. Closed Large Cell Clouds

    Atmospheric Science Data Center

    2013-04-19

    article title:  Closed Large Cell Clouds in the South Pacific     ... unperturbed by cyclonic or frontal activity. When the cell centers are cloudy and the main sinking motion is concentrated at cell ...

  17. Prometheus Up Close

    NASA Image and Video Library

    2015-12-08

    NASA Cassini spacecraft spied details on the pockmarked surface of Saturn moon Prometheus 86 kilometers, or 53 miles across during a moderately close flyby on Dec. 6, 2015. This is one of Cassini highest resolution views of Prometheus.

  18. Closed Circular Chains

    ERIC Educational Resources Information Center

    Caglayan, Günhan

    2016-01-01

    A Steiner chain is defined as the sequence of n circles that are all tangent to two given non-intersecting circles. A closed chain, in particular, is one in which every circle in the sequence is tangent to the previous and next circles of the chain. In a closed Steiner chain the first and the "n"th circles of the chain are also tangent…

  19. Closed Circular Chains

    ERIC Educational Resources Information Center

    Caglayan, Günhan

    2016-01-01

    A Steiner chain is defined as the sequence of n circles that are all tangent to two given non-intersecting circles. A closed chain, in particular, is one in which every circle in the sequence is tangent to the previous and next circles of the chain. In a closed Steiner chain the first and the "n"th circles of the chain are also tangent…

  20. Closed inductively coupled plasma cell

    DOEpatents

    Manning, T.J.; Palmer, B.A.; Hof, D.E.

    1990-11-06

    A closed inductively coupled plasma cell generates a relatively high power, low noise plasma for use in spectroscopic studies is disclosed. A variety of gases can be selected to form the plasma to minimize spectroscopic interference and to provide a electron density and temperature range for the sample to be analyzed. Grounded conductors are placed at the tube ends and axially displaced from the inductive coil, whereby the resulting electromagnetic field acts to elongate the plasma in the tube. Sample materials can be injected in the plasma to be excited for spectroscopy. 1 fig.

  1. Closed inductively coupled plasma cell

    DOEpatents

    Manning, Thomas J.; Palmer, Byron A.; Hof, Douglas E.

    1990-01-01

    A closed inductively coupled plasma cell generates a relatively high power, low noise plasma for use in spectroscopic studies. A variety of gases can be selected to form the plasma to minimize spectroscopic interference and to provide a electron density and temperature range for the sample to be analyzed. Grounded conductors are placed at the tube ends and axially displaced from the inductive coil, whereby the resulting electromagnetic field acts to elongate the plasma in the tube. Sample materials can be injected in the plasma to be excited for spectroscopy.

  2. Unbalanced Peptidergic Inhibition in Superficial Neocortex Underlies Spike and Wave Seizure Activity

    PubMed Central

    Hall, S.; Hunt, M.; Simon, A.; Cunnington, L.G.; Carracedo, L.M.; Schofield, I.S.; Forsyth, R.; Traub, R.D.

    2015-01-01

    Slow spike and wave discharges (0.5–4 Hz) are a feature of many epilepsies. They are linked to pathology of the thalamocortical axis and a thalamic mechanism has been elegantly described. Here we present evidence for a separate generator in local circuits of associational areas of neocortex manifest from a background, sleep-associated delta rhythm in rat. Loss of tonic neuromodulatory excitation, mediated by nicotinic acetylcholine or serotonin (5HT3A) receptors, of 5HT3-immunopositive interneurons caused an increase in amplitude and slowing of the delta rhythm until each period became the “wave” component of the spike and wave discharge. As with the normal delta rhythm, the wave of a spike and wave discharge originated in cortical layer 5. In contrast, the “spike” component of the spike and wave discharge originated from a relative failure of fast inhibition in layers 2/3—switching pyramidal cell action potential outputs from single, sparse spiking during delta rhythms to brief, intense burst spiking, phase-locked to the field spike. The mechanisms underlying this loss of superficial layer fast inhibition, and a concomitant increase in slow inhibition, appeared to be precipitated by a loss of neuropeptide Y (NPY)-mediated local circuit inhibition and a subsequent increase in vasoactive intestinal peptide (VIP)-mediated disinhibition. Blockade of NPY Y1 receptors was sufficient to generate spike and wave discharges, whereas blockade of VIP receptors almost completely abolished this form of epileptiform activity. These data suggest that aberrant, activity-dependent neuropeptide corelease can have catastrophic effects on neocortical dynamics. PMID:26109655

  3. Unbalanced Peptidergic Inhibition in Superficial Neocortex Underlies Spike and Wave Seizure Activity.

    PubMed

    Hall, S; Hunt, M; Simon, A; Cunnington, L G; Carracedo, L M; Schofield, I S; Forsyth, R; Traub, R D; Whittington, M A

    2015-06-24

    Slow spike and wave discharges (0.5-4 Hz) are a feature of many epilepsies. They are linked to pathology of the thalamocortical axis and a thalamic mechanism has been elegantly described. Here we present evidence for a separate generator in local circuits of associational areas of neocortex manifest from a background, sleep-associated delta rhythm in rat. Loss of tonic neuromodulatory excitation, mediated by nicotinic acetylcholine or serotonin (5HT3A) receptors, of 5HT3-immunopositive interneurons caused an increase in amplitude and slowing of the delta rhythm until each period became the "wave" component of the spike and wave discharge. As with the normal delta rhythm, the wave of a spike and wave discharge originated in cortical layer 5. In contrast, the "spike" component of the spike and wave discharge originated from a relative failure of fast inhibition in layers 2/3-switching pyramidal cell action potential outputs from single, sparse spiking during delta rhythms to brief, intense burst spiking, phase-locked to the field spike. The mechanisms underlying this loss of superficial layer fast inhibition, and a concomitant increase in slow inhibition, appeared to be precipitated by a loss of neuropeptide Y (NPY)-mediated local circuit inhibition and a subsequent increase in vasoactive intestinal peptide (VIP)-mediated disinhibition. Blockade of NPY Y1 receptors was sufficient to generate spike and wave discharges, whereas blockade of VIP receptors almost completely abolished this form of epileptiform activity. These data suggest that aberrant, activity-dependent neuropeptide corelease can have catastrophic effects on neocortical dynamics. Copyright © 2015 Hall et al.

  4. Molecular marker-based prediction of hybrid performance in maize using unbalanced data from multiple experiments with factorial crosses.

    PubMed

    Schrag, Tobias A; Möhring, Jens; Maurer, Hans Peter; Dhillon, Baldev S; Melchinger, Albrecht E; Piepho, Hans-Peter; Sørensen, Anker P; Frisch, Matthias

    2009-02-01

    In hybrid breeding, the prediction of hybrid performance (HP) is extremely important as it is difficult to evaluate inbred lines in numerous cross combinations. Recent developments such as doubled haploid production and molecular marker technologies have enhanced the prospects of marker-based HP prediction to accelerate the breeding process. Our objectives were to (1) predict HP using a combined analysis of hybrids and parental lines from a breeding program, (2) evaluate the use of molecular markers in addition to phenotypic and pedigree data, (3) evaluate the combination of line per se data with marker-based estimates, (4) study the effect of the number of tested parents, and (5) assess the advantage of haplotype blocks. An unbalanced dataset of 400 hybrids from 9 factorial crosses tested in different experiments and data of 79 inbred parents were subjected to combined analyses with a mixed linear model. Marker data of the inbreds were obtained with 20 AFLP primer-enzyme combinations. Cross-validation was used to assess the performance prediction of hybrids of which no or only one parental line was testcross evaluated. For HP prediction, the highest proportion of explained variance (R (2)), 46% for grain yield (GY) and 70% for grain dry matter content (GDMC), was obtained from line per se best linear unbiased prediction (BLUP) estimates plus marker effects associated with mid-parent heterosis (TEAM-LM). Our study demonstrated that HP was efficiently predicted using molecular markers even for GY when testcross data of both parents are not available. This can help in improving greatly the efficiency of commercial hybrid breeding programs.

  5. Grafts in "closed" rhinoplasty.

    PubMed

    Scattolin, A; D'Ascanio, L

    2013-06-01

    Rhinoplasty is a fascinating and complex surgical procedure aiming at attaining a well-functioning and aesthetically pleasant nose. The use of grafts is of the utmost importance for the nasal surgeon to achieve such results. However, the philosophy and technical use of nasal grafts are different in "closed" and "open" rhinoplasty. The aim of this paper is not detailed description of the numerous grafts reported in the literature; we will describe the main principles of grafts use in "closed" rhinoplasty derived from our experience, with special reference to the philosophical and technical differences in their employment between "closed" and "open" rhinoplasty. Some cases are reported as an example of graft use in "endonasal" approach rhinoplasty.

  6. Closed flexor tendon ruptures.

    PubMed

    Netscher, David T; Badal, Justin J

    2014-11-01

    We review different causes, diagnoses, and treatment options of closed flexor tendon disruptions in the hand. A classification of closed tendon ruptures based on their mechanism includes traumatic tendon avulsion, spontaneous midsubstance rupture, attrition rupture, infiltrative tenosynovial rupture, and iatrogenic. Certain conditions result in tendon disruption inflicted by more than 1 of these etiologies. In rheumatoid arthritis, tendon rupture may result from attrition on an exposed rough surface, proliferative tenosynovial tendon infiltration, or steroid use. Copyright © 2014 American Society for Surgery of the Hand. Published by Elsevier Inc. All rights reserved.

  7. Closed Orbits in Phase Space

    NASA Astrophysics Data System (ADS)

    Murphy, Andrew; Haestad, Jace; Morgan, Thomas

    2015-09-01

    We report characteristics of closed classical orbits in an electric field in phase space produced in photoabsorption. Rydberg states of atomic and molecular hydrogen and helium are considered. The core potential used for the hydrogen molecule is an effective one electron one center core potential evaluated at the internuclear equilibrium distance. Poincare surfaces of section in phase space are generated by integrating the equations of motion in semiparabolic coordinates u = (r + z) 1 / 2 and v = (r - z) 1 / 2, and plotting the location in phase space (pv versus v) whenever u = 0, with the electric field in the z direction. Combination orbits produced by Rydberg electron core scattering are studied and the evolution in phase space of these combination orbits due to scattering from one closed orbit into another is investigated. Connections are made to measured laser photoabsorption experiments that excite Rydberg states (20 < n < 30) and produce accompanying scaled energy recurrence spectra. The phase space structures responsible for the spectra are identified.

  8. Closing the Loop Sampler.

    ERIC Educational Resources Information Center

    California Integrated Waste Management Board, Sacramento.

    Closing the Loop (CTL) is a science curriculum designed to introduce students to integrated waste management through awareness. This document presents five lesson plans focusing on developing an understanding of natural resources, solid wastes, conservation, and the life of landfills. Contents include: (1) "What Are Natural Resources?"; (2)…

  9. Review: The Closing Circle

    ERIC Educational Resources Information Center

    Environment, 1972

    1972-01-01

    Two views of prominent biologists are presented side-by-side. Focal point is Barry Commoner's book, The Closing Circle, with a subsequent review by Paul Ehrlich. Growth of population, increases in affluence, and increased pollution from products of technology are considered. (BL)

  10. Closed Captioning: Students' Responses.

    ERIC Educational Resources Information Center

    Weasenforth, Donald L.

    A study investigated the attitudes of adult university students of English as a Second Language (ESL) toward use of closed captioned television (CCTV) as an instructional tool. Students at the intermediate (n=51) and advanced (n=55) levels of ESL study in classes using CCTV were administered a questionnaire concerning their perceptions of the…

  11. Surgical wound care -- closed

    MedlinePlus

    ... around the incision increases or becomes thick, tan, green, or yellow, or smells bad (pus). Also call if your temperature is above 100°F (37.7°C) for more than 4 hours. Alternative Names Surgical incision care; Closed wound care References Leong M, Phillips LG. ...

  12. Closed Small Cell Clouds

    Atmospheric Science Data Center

    2013-04-19

    ... (right)   The structure of tightly packed "closed cells" in a layer of marine stratocumulus over the southeastern Pacific Ocean ... into interesting structures such as those shown here. These cells are notably small, with diameters ranging from 10-15 kilometers, instead ...

  13. Closing the Performance Gap.

    ERIC Educational Resources Information Center

    Riggins, Cheryl G.

    2002-01-01

    Describes how the principal of a K-2, 400-student suburban elementary school near Flint, Michigan, worked with her staff and superintendent to develop and implement a strategic plan to close the student achievement gap. Reports significant improvement in reading and math scores after 1 year. (PKP)

  14. Closing the Loop Sampler.

    ERIC Educational Resources Information Center

    California Integrated Waste Management Board, Sacramento.

    Closing the Loop (CTL) is a science curriculum designed to introduce students to integrated waste management through awareness. This document presents five lesson plans focusing on developing an understanding of natural resources, solid wastes, conservation, and the life of landfills. Contents include: (1) "What Are Natural Resources?"; (2)…

  15. Closing the Performance Gap.

    ERIC Educational Resources Information Center

    Riggins, Cheryl G.

    2002-01-01

    Describes how the principal of a K-2, 400-student suburban elementary school near Flint, Michigan, worked with her staff and superintendent to develop and implement a strategic plan to close the student achievement gap. Reports significant improvement in reading and math scores after 1 year. (PKP)

  16. Closing the Assessment Loop

    ERIC Educational Resources Information Center

    Banta, Trudy W.; Blaich, Charles

    2011-01-01

    Accreditors, speakers at assessment conferences, and campus leaders all decry the fact that too few faculty are closing the loop--that is, studying assessment findings to see what improvements might be suggested and taking the appropriate steps to make them. This is difficult enough with locally developed measures; adding the need to interpret…

  17. Review: The Closing Circle

    ERIC Educational Resources Information Center

    Environment, 1972

    1972-01-01

    Two views of prominent biologists are presented side-by-side. Focal point is Barry Commoner's book, The Closing Circle, with a subsequent review by Paul Ehrlich. Growth of population, increases in affluence, and increased pollution from products of technology are considered. (BL)

  18. Gross regional domestic product estimation: Application of two-way unbalanced panel data models to economic growth in East Nusa Tenggara province

    NASA Astrophysics Data System (ADS)

    Wibowo, Wahyu; Sinu, Elisabeth B.; Setiawan

    2017-03-01

    The condition of East Nusa Tenggara Province which recently developed new districts can affect the number of information or data collected become unbalanced. One of the consequences of ignoring the data incompleteness is the estimator become not valid. Therefore, the analysis of unbalanced panel data is very crucial.The aim of this paper is to find the estimation of Gross Regional Domestic Product in East Nusa Tenggara Province using unbalanced panel data regression model for two-way error component which assume random effect model (REM). In this research, we employ Feasible Generalized Least Squares (FGLS) as regression coefficients estimation method. Since variance of the model is unknown, ANOVA method is considered to obtain the variance components in order to construct the variance-covariance matrix. The data used in this research is secondary data taken from Central Bureau of Statistics of East Nusa Tenggara Province in 21 districts period 2004-2013. The predictors are the number of labor over 15 years old (X1), electrification ratios (X2), and local revenues (X3) while Gross Regional Domestic Product based on constant price 2000 is the response (Y). The FGLS estimation result shows that the value of R2 is 80,539% and all the predictors chosen are significantly affect (α = 5%) the Gross Regional Domestic Product in all district of East Nusa Tenggara Province. Those variables are the number of labor over 15 years old (X1), electrification ratios (X2), and local revenues (X3) with 0,22986, 0,090476, and 0,14749 of elasticities, respectively.

  19. Incorporation of 5-ethynyl-2'-deoxyuridine (EdU) as a novel strategy for identification of the skewed X inactivation pattern in balanced and unbalanced X-rearrangements.

    PubMed

    Sisdelli, Luiza; Vidi, Angela Cristina; Moysés-Oliveira, Mariana; Di Battista, Adriana; Bortolai, Adriana; Moretti-Ferreira, Danilo; da Silva, Magnus R Dias; Melaragno, Maria Isabel; Carvalheira, Gianna

    2016-02-01

    X-chromosome inactivation occurs randomly in normal female cells. However, the inactivation can be skewed in patients with alterations in X-chromosome. In balanced X-autosome translocations, normal X is preferentially inactivated, while in unbalanced X alterations, the aberrant X is usually inactivated. Here, we present a novel strategy to verify the skewed X inactivation pattern through the incorporation of 5-ethynyl-2'-deoxyuridine (EdU) into cells, in 11 patients: five carriers of balanced X-autosome translocations and six of unbalanced X-chromosome alterations. Since EdU is a labeled nucleoside analog of thymidine, its incorporation during DNA synthesis can reveal late replication regions and the inactive X-chromosome. All EdU findings were validated by the human androgen receptor gene (HUMARA) assay. The late replication regions were easily and quickly visualized in all cells, where inactive Xs are marked with strong green fluorescence. It was observed that the normal X-chromosome was preferentially inactivated in patients with balanced X-autosome translocations; while the aberrant X-chromosome was inactivated in most cells from patients with unbalanced alterations. By performing the fluorescence-based EdU assay, the differences between the active and inactive X-chromosomes are more easily recognizable than by classic cytogenetic methods. Furthermore, EdU incorporation allows the observation of the late replication regions in autosomal segments present in X derivatives from X-autosome translocations. Therefore, EdU assay permits an accurate and efficient cytogenetic evaluation of the X inactivation pattern with a low-cost, easy to perform and highly reproducible technique.

  20. Close Quarters Combat Shooting

    DTIC Science & Technology

    2010-04-14

    1994.at the Palm Beach Community College Criminal Justice Institute ofLakeworth, Florida to the more dynamic force-on-force, realistic scenario...Highway, Suite 1204, Arlington, VA 22202-4302, and to the Office of Management and Budget, Paperwork Reduction Project (0704-0188) Washington, DC...Shooting is the Superior Method for Close Quarters Combat 5b. GRANT NUMBER Shooting" N/A Sc. PROGRAM ELEMENT NUMBER N/A 6. AUTHOR( S ) Sd. PROJECT

  1. Closing the Pay Gap

    DTIC Science & Technology

    2000-10-01

    the pay gap has been narrowed, hut only to just under 10 percent. And current military compensation legislation does not close the gap until 2026. There...will continue to be a pay gap until 2026 unless the next administration and the next Congress provide more for pay above the 1999 legislated ramp- up...of .5 percent (one half of one percent) per year to attain pay equality . That means that soldiers, sailors, airmen, marines and Coast Guardsmen

  2. An Unbalanced Crucible

    ERIC Educational Resources Information Center

    Deneen, Patrick J.

    2012-01-01

    Long regarded by the vanguard of America's universities as antiquated and even dangerous, civic education is suddenly fashionable again. With the publication of "A Crucible Moment," a long battle in the culture wars appears to be winding down. It appears that everyone supports civic education today. For the past three decades, the ideal of civic…

  3. An unbalanced portfolio.

    PubMed

    Federsel, Hans-Jurgen

    2009-06-01

    An excellent demonstration of how meaningful and valuable conferences devoted to the topic of project and portfolio management in the pharmaceutical industry can be, was given at an event organized in Barcelona, September 2008. Thus, over this 2-day meeting the delegates were updated on the state of the art in this wide-reaching area from speakers representing an array of companies; from small, relatively new players, via mid-sized, to established large and big pharmas. One common theme that emerged was the importance of assessing the value of drug projects as correctly as possible, especially under the current financial climate and the many challenges facing the industry. Furthermore, experiences from constructing portfolios with the aim to minimize risk and maximize return on investment were shared alongside mathematical approaches to obtain the data required for this purpose and accounts of the pleasures and hardships working in a global context and in partnership constellations.

  4. An Unbalanced Crucible

    ERIC Educational Resources Information Center

    Deneen, Patrick J.

    2012-01-01

    Long regarded by the vanguard of America's universities as antiquated and even dangerous, civic education is suddenly fashionable again. With the publication of "A Crucible Moment," a long battle in the culture wars appears to be winding down. It appears that everyone supports civic education today. For the past three decades, the ideal of civic…

  5. Control of the stabilization of cubic boron nitride thin films deposited by unbalanced magnetron sputtering and dc pulsed substrate biasing

    NASA Astrophysics Data System (ADS)

    Otano-Rivera, Wilfredo

    The formation of cubic boron nitride (cBN) thin films deposited by unbalanced magnetron sputtering and dc pulsed substrate biasing has been studied. Thin films were deposited at different pressures and negative bias voltages to study the effect of the energetic bombardment on the stabilization conditions of the cubic phase of BN thin films. It is shown that it is possible to clearly define a stabilization window for cBN by controlling the sputtering deposition process parameters of pressure and negative substrate bias. It is also shown that at higher deposition pressures charge exchange and momentum transfer collisions in the plasma sheath reduce the bombardment energy of the particles. These collisional processes result in the use of a higher substrate bias voltages for increasing gas pressures in order to maintain the momentum per arriving boron atom, P/a, imparted to the growing film inside the stabilization window for the cubic phase. The end result is a trend where the substrate bias voltage for the formation of cBN increases negatively as a function of pressure times sheath thickness. A series of films were also deposited on different types of substrates in order to study the effects of chemistry and epitaxy on the nucleation of cBN. It was possible to nucleate the BN cubic phase on a wide variety of substrates. Diamond coated silicon substrates were the only ones that showed a marked effect on the nucleation of the cBN, where the FWHM of the FTIR signal was reduced two-fold as compared to the FTIR signal of films deposited on silicon under similar deposition conditions. The experimental results suggest that there is a threshold energy for the bombarding ions below which it is not possible to nucleate cBN. This result, in combination with the fact that P/a controls the cBN stabilization during the nucleation stage and other reported observations pertinent to the cBN thin film formation, leads to a proposed mechanism for the nucleation and growth stages of cBN.

  6. Reheating for closed string inflation

    SciTech Connect

    Cicoli, Michele; Mazumdar, Anupam E-mail: a.mazumdar@lancaster.ac.uk

    2010-09-01

    We point out some of the outstanding challenges for embedding inflationary cosmology within string theory studying the process of reheating for models where the inflaton is a closed string mode parameterising the size of an internal cycle of the compactification manifold. A realistic model of inflation must explain the tiny perturbations in the cosmic microwave background radiation and also how to excite the ordinary matter degrees of freedom after inflation, required for the success of Big Bang Nucleosynthesis. We study these issues focusing on two promising inflationary models embedded in LARGE volume type IIB flux compactifications. We show that phenomenological requirements and consistency of the effective field theory treatment imply the presence at low energies of a hidden sector together with a visible sector, where the Minimal Supersymmetric Standard Model fields are residing. A detailed calculation of the inflaton coupling to the fields of the hidden sector, visible sector, and moduli sector, reveals that the inflaton fails to excite primarily the visible sector fields, instead hidden sector fields are excited copiously after the end of inflation. This sets severe constraints on hidden sector model building where the most promising scenario emerges as a pure N = 1 SYM theory, forbidding the kinematical decay of the inflaton to the hidden sector. In this case it is possible to reheat the Universe with the visible degrees of freedom even though in some cases we discover a new tension between TeV scale SUSY and reheating on top of the well-known tension between TeV scale SUSY and inflation.

  7. West syndrome associated with a novel chromosomal anomaly; partial trisomy 8P together with partial monosomy 9P, resulting from a familial unbalanced reciprocal translocation

    PubMed Central

    Erol, Ilknur; Saygı, Semra; Demir, Şenay; Alehan, Fusun; Sahin, Feride Iffet

    2015-01-01

    West syndrome is classified according to the underlying etiology into an acquired West syndrome, a congenital/developmental West syndrome, and West syndrome of unknown etiology. Causes of a congenital/developmental West syndrome are extensive and include chromosomal anomalies. We report on a patient carrying a derivative chromosome originating from the reciprocal unbalanced translocation t (8;9) (p11.2;p22) and presenting with macrocephaly, West syndrome, severe mental motor retardation and hypotonia. As far as we know, this is a new chromosomal anomaly associated with West syndrome. PMID:25878738

  8. Cluster randomised crossover trials with binary data and unbalanced cluster sizes: application to studies of near-universal interventions in intensive care.

    PubMed

    Forbes, Andrew B; Akram, Muhammad; Pilcher, David; Cooper, Jamie; Bellomo, Rinaldo

    2015-02-01

    Cluster randomised crossover trials have been utilised in recent years in the health and social sciences. Methods for analysis have been proposed; however, for binary outcomes, these have received little assessment of their appropriateness. In addition, methods for determination of sample size are currently limited to balanced cluster sizes both between clusters and between periods within clusters. This article aims to extend this work to unbalanced situations and to evaluate the properties of a variety of methods for analysis of binary data, with a particular focus on the setting of potential trials of near-universal interventions in intensive care to reduce in-hospital mortality. We derive a formula for sample size estimation for unbalanced cluster sizes, and apply it to the intensive care setting to demonstrate the utility of the cluster crossover design. We conduct a numerical simulation of the design in the intensive care setting and for more general configurations, and we assess the performance of three cluster summary estimators and an individual-data estimator based on binomial-identity-link regression. For settings similar to the intensive care scenario involving large cluster sizes and small intra-cluster correlations, the sample size formulae developed and analysis methods investigated are found to be appropriate, with the unweighted cluster summary method performing well relative to the more optimal but more complex inverse-variance weighted method. More generally, we find that the unweighted and cluster-size-weighted summary methods perform well, with the relative efficiency of each largely determined systematically from the study design parameters. Performance of individual-data regression is adequate with small cluster sizes but becomes inefficient for large, unbalanced cluster sizes. When outcome prevalences are 6% or less and the within-cluster-within-period correlation is 0.05 or larger, all methods display sub-nominal confidence interval coverage

  9. West syndrome associated with a novel chromosomal anomaly; partial trisomy 8P together with partial monosomy 9P, resulting from a familial unbalanced reciprocal translocation.

    PubMed

    Erol, Ilknur; Saygı, Semra; Demir, Şenay; Alehan, Fusun; Sahin, Feride Iffet

    2015-01-01

    West syndrome is classified according to the underlying etiology into an acquired West syndrome, a congenital/developmental West syndrome, and West syndrome of unknown etiology. Causes of a congenital/developmental West syndrome are extensive and include chromosomal anomalies. We report on a patient carrying a derivative chromosome originating from the reciprocal unbalanced translocation t (8;9) (p11.2;p22) and presenting with macrocephaly, West syndrome, severe mental motor retardation and hypotonia. As far as we know, this is a new chromosomal anomaly associated with West syndrome.

  10. Composite cavity based fiber optic Fabry Perot strain sensors demodulated by an unbalanced fiber optic Michelson interferometer with an electrical scanning mirror

    NASA Astrophysics Data System (ADS)

    Zhang, Jianzhong; Yang, Jun; Sun, Weimin; Jin, Wencai; Yuan, Libo; Peng, G. D.

    2008-08-01

    A composite cavity based fiber optic Fabry-Perot strain sensor system, interrogated by a white light source and demodulated by an unbalanced fiber optic Michelson interferometer with an electrical scanning mirror, is proposed and demonstrated. Comparing with the traditional extrinsic fiber optic Fabry-Perot strain sensor, the potential multiplexing capability and the dynamic measurement range are improved simultaneously. At the same time, the measurement stability of the electrical scanning mirror system is improved by the self-referenced signal of the sensor structure.

  11. Bringing closed-loop home: recent advances in closed-loop insulin delivery.

    PubMed

    Thabit, Hood; Hovorka, Roman

    2014-04-01

    To highlight the recent advances in closed-loop research, the development and progress towards utilizing closed loop outside of the clinical research setting and at patients' homes. In spite of the modern insulin therapy in type 1 diabetes, hypoglycaemia is still a major limiting factor. This often leads to suboptimal glycaemic control and risk of diabetes complications. Closed loop has been shown to improve glycaemic control whilst avoiding hypoglycaemia. Incremental progress has been made in this field, from the use of automated systems and bihormonal closed-loop systems in clinical research facility settings under close supervision to the use of ambulatory closed-loop prototype at patients' homes in free-living conditions. Different population of patients with type 1 diabetes and control algorithm approaches have been studied, assessing the efficacy and safety. Transitional and home studies present different challenges at achieving better glycaemic outcome with closed loop. Improved glucose sensor reliability may accelerate the clinical use and faster insulin analogues increase the clinical utility. Results and experience with closed-loop insulin delivery have been encouraging, leading the way for future improvements and development in the field, to make closed loop suitable for use in clinical practice.

  12. Rings from Close Encounters

    NASA Astrophysics Data System (ADS)

    Kohler, Susanna

    2016-09-01

    Weve recently discovered narrow sets of rings around two minor planets orbiting in our solar system. How did these rings form? A new study shows that they could be a result of close encounters between the minor planets and giants like Jupiter or Neptune.Unexpected Ring SystemsPositions of the centaurs in our solar system (green). Giant planets (red), Jupiter trojans (grey), scattered disk objects (tan) and Kuiper belt objects (blue) are also shown. [WilyD]Centaurs are minor planets in our solar system that orbit between Jupiter and Neptune. These bodies of which there are roughly 44,000 with diameters larger than 1 km have dynamically unstable orbits that cross paths with those of one or more giant planets.Recent occultation observations of two centaurs, 10199 Chariklo and 2060 Chiron, revealed that these bodies both host narrow ring systems. Besides our four giant planets, Chariklo and Chiron are the only other bodies in the solar system known to have rings. But how did these rings form?Scientists have proposed several models, implicating collisions, disruption of a primordial satellite, or dusty outgassing. But a team of scientists led by Ryuki Hyodo (Paris Institute of Earth Physics, Kobe University) has recently proposed an alternative scenario: what if the rings were formed from partial disruption of the centaur itself, after it crossed just a little too close to a giant planet?Tidal Forces from a GiantHyodo and collaborators first used past studies of centaur orbits to estimate that roughly 10% of centaurs experience close encounters (passing within a distance of ~2x the planetary radius) with a giant planet during their million-year lifetime. The team then performed a series of simulations of close encounters between a giant planet and a differentiated centaur a body in which the rocky material has sunk to form a dense silicate core, surrounded by an icy mantle.Some snapshots of simulation outcomes (click for a closer look!) for different initial states of

  13. Closed loop electrostatic levitation system

    NASA Technical Reports Server (NTRS)

    Rhim, W. K.; Saffren, M. M.; Elleman, D. D. (Inventor)

    1985-01-01

    An electrostatic levitation system is described, which can closely control the position of objects of appreciable size. A plurality of electrodes surround the desired position of an electrostatically charged object, the position of the objects is monitored, and the voltages applied to the electrodes are varied to hold the object at a desired position. In one system, the object is suspended above a plate-like electrode which has a concave upper face to urge the object toward the vertical axis of the curved plate. An upper electrode that is also curved can be positioned above the object, to assure curvature of the field at any height above the lower plate. In another system, four spherical electrodes are positioned at the points of a tetrahedron, and the voltages applied to the electrodes are varied in accordance with the object position as detected by two sensors.

  14. Close encounters with DNA

    PubMed Central

    Maffeo, C.; Yoo, J.; Comer, J.; Wells, D. B.; Luan, B.; Aksimentiev, A.

    2014-01-01

    Over the past ten years, the all-atom molecular dynamics method has grown in the scale of both systems and processes amenable to it and in its ability to make quantitative predictions about the behavior of experimental systems. The field of computational DNA research is no exception, witnessing a dramatic increase in the size of systems simulated with atomic resolution, the duration of individual simulations and the realism of the simulation outcomes. In this topical review, we describe the hallmark physical properties of DNA from the perspective of all-atom simulations. We demonstrate the amazing ability of such simulations to reveal the microscopic physical origins of experimentally observed phenomena and we review the frustrating limitations associated with imperfections of present atomic force fields and inadequate sampling. The review is focused on the following four physical properties of DNA: effective electric charge, response to an external mechanical force, interaction with other DNA molecules and behavior in an external electric field. PMID:25238560

  15. Unbalanced discharging and aging due to temperature differences among the cells in a lithium-ion battery pack with parallel combination

    NASA Astrophysics Data System (ADS)

    Yang, Naixing; Zhang, Xiongwen; Shang, BinBin; Li, Guojun

    2016-02-01

    This paper presents an investigation on the unbalanced discharging and aging due to temperature difference between the parallel-connected cells. A thermal-electrochemical model is developed for the parallel-connected battery pack. The effects of temperature difference on the unbalanced discharging performances are studied by simulations and experiments. For the parallel-connected cells, the cell at higher temperature experiences a larger current in the early discharging process before approximately 75% of depth of discharge (DOD). When the discharge process approaches the voltage turn point of the battery pack, the discharge current through the cell at higher temperature begins to decrease significantly. After the DOD reaches approximately 90%, the discharge current of the cell at higher temperature rises again. Correspondingly, the changes in the discharging current through the cell at lower temperature are opposite to that of the cell at higher temperature. Simulations also show that the temperature difference between the parallel-connected cells greatly aggravates the imbalance discharge phenomenon between the cells, which accelerates the losses of the battery pack capacity. For the parallel-connected battery pack, the capacity loss rate approximately increases linearly as the temperature difference between the cells increases. This trend is magnified with the increase of operating temperature.

  16. Is classic pericentric inversion of chromosome 2 inv(2)(p11q13) associated with an increased risk of unbalanced chromosomes?

    PubMed

    Ferfouri, Fatma; Clement, Patrice; Gomes, Denise Molina; Minz, Marie; Amar, Edouard; Selva, Jacqueline; Vialard, François

    2009-10-01

    To study pericentric inversion segregation and interchromosomal effect on sperm for men heterozygous for inv(2)(p11q13), to assess the risk of miscarriage. Case report. Department of reproductive biology, cytogenetics, gynecology, and obstetrics. Seven patients heterozygous for inv(2)(p11q13) and five patients with normal karyotype with experience of recurrent spontaneous miscarriage. Fluorescence in situ hybridization on sperm with 2 p and 2q subtelomeric probes to screen for inversion segregation, and X, Y, and 18 centromeric probes to study interchromosomal effects. One thousand sperm were analyzed per experiment and per patient. Rate of unbalanced chromosomes and aneuploid sperm. The inv(2)(p11q13) patients showed a 0.3% rate of sperm with unbalanced chromosomes. For interchromosomal effects, a 0.6% aneuploid sperm rate was observed for patients heterozygous for inv(2)(p11q13). This is similar to the 0.5% rate observed for control patients. Inv(2)(p11q13) seems not to increase miscarriage for couples with men heterozygous for this inversion.

  17. Modified DSTATCOM Topology with Reduced DC Link Voltage for Reactive and Harmonic Power Compensation of Unbalanced Nonlinear Load in Distribution System

    NASA Astrophysics Data System (ADS)

    Geddada, Nagesh; Karanki, Srinivas B.; Mishra, Mahesh K.

    2014-06-01

    This paper proposes a modified four-leg distribution static compensator (DSTATCOM) topology for compensation of unbalanced and nonlinear loads in three-phase four-wire distribution system. DSTATCOM, connected in parallel to the load, supplies reactive and harmonic powers demanded by unbalanced nonlinear loads. In this proposed topology, the voltage source inverter (VSI) of DSTATCOM is connected to point of common coupling (point of interconnection of source, load, DSTATCOM) through interface inductor and series capacitance, unlike the conventional topology which consists of interface inductor alone. Load compensation with a lower value of input DC link voltage of VSI is possible in this modified topology compared to conventional topology. A comparative study on modified and conventional topologies in terms of voltage rating of inverter power switches, switching losses in VSI and power rating of input DC capacitor of VSI is presented. The detailed design aspects of DC link capacitor and interface series capacitor are also presented. The reference filter currents are generated using instantaneous symmetrical component theory and are tracked using hysteresis current control technique. A detailed simulation study is carried out, to compare the compensation performances of conventional, modified topologies using PSCAD simulator and experimental studies are done to validate the simulation results.

  18. Closing Photoconductive Semiconductor Switches

    DTIC Science & Technology

    1989-06-01

    impedance voltage source. Recently, we tested the dependance of the lock-on field on the amount of neutron bombardment of the GaAs. This treatment...for about 30 minutes. Conclusions In this paper have demonstrated a large temperature dependance of the characteristics of GaAs PCSS. The most

  19. Close Call: Marloes Again.

    ERIC Educational Resources Information Center

    Journal of Adventure Education and Outdoor Leadership, 1994

    1994-01-01

    Teachers on a high school field trip used quick thinking when rescuing two students trapped in a small bay by a rising tide and a rocky coastline. Emphasizes that teachers should never assume that students will follow rules and must check frequently when supervising student groups. (LP)

  20. Close Call: Marloes Again.

    ERIC Educational Resources Information Center

    Journal of Adventure Education and Outdoor Leadership, 1994

    1994-01-01

    Teachers on a high school field trip used quick thinking when rescuing two students trapped in a small bay by a rising tide and a rocky coastline. Emphasizes that teachers should never assume that students will follow rules and must check frequently when supervising student groups. (LP)

  1. Multipurpose closed-circuit television teaching cart.

    PubMed

    Folberg, R; Verdick, R E

    1987-08-01

    We developed a mobile closed-circuit television cart for resident and staff presentations at rounds, and fluorescein angiography and pathology conferences. The system, operated without special training, permits presentation of x-rays, CT scans, visual fields, echographic and electrophysiologic tracings, fluorescein angiograms, color photographs, 35 mm slides, and printed text on standard closed-circuit television monitors. For pathology conferences, gross dissections, slides of whole eyes and standard high power microscopic fields may be shown. The cart can be assembled using readily available components for the same cost as a stand-alone glass slide projector. Mounted on wheels, the entire unit may be moved to any location equipped with closed circuit television monitors. Because the cart can be used to teach nearly every medical discipline, the cost of construction can be shared by a number of departments.

  2. Position Paper on School Closings.

    ERIC Educational Resources Information Center

    Twenty-First Century School Fund, Washington, DC.

    A position paper addresses the current round of school closings in the District of Columbia arguing that these closings are not within the context of the 10-year educational facilities plan that included community input, and valid criteria for closing decisions being consistently and objectively applied. Current closings decisions are viewed as…

  3. Spectral-domain-based scattering analysis of fields radiated by distributed sources in planar-stratified environments with arbitrarily anisotropic layers

    NASA Astrophysics Data System (ADS)

    Sainath, Kamalesh; Teixeira, Fernando L.

    2014-12-01

    We discuss the numerically stable, spectral-domain computation and extraction of the scattered electromagnetic field excited by distributed sources embedded in planar-layered environments, where each layer may exhibit arbitrary and independent electrical and magnetic anisotropic response and loss profiles. This stands in contrast to many standard spectral-domain algorithms that are restricted to computing the fields radiated by Hertzian dipole sources in planar-layered environments where the media possess azimuthal-symmetric material tensors (i.e., isotropic, and certain classes of uniaxial, media). Although computing the scattered field, particularly when due to distributed sources, appears (from the analytical perspective, at least) relatively straightforward, different procedures within the computation chain, if not treated carefully, are inherently susceptible to numerical instabilities and (or) accuracy limitations due to the potential manifestation of numerically overflown and (or) numerically unbalanced terms entering the chain. Therefore, primary emphasis herein is given to effecting these tasks in a numerically stable and robust manner for all ranges of physical parameters. After discussing the causes behind, and means to mitigate, these sources of numerical instability, we validate the algorithm's performance against closed-form solutions. Finally, we validate and illustrate the applicability of the proposed algorithm in case studies concerning active remote sensing of marine hydrocarbon reserves embedded deep within lossy, planar-layered media.

  4. Do closed universes recollapse?

    NASA Astrophysics Data System (ADS)

    Tipler, Frank J.

    The conditions for recollapse in universes with compact maximal hypersurfaces are investigated theoretically, reviewing the results of recent investigations. The importance of recollapse for observational astrophysics is briefly discussed, and particular attention is given to the implications of maximal hypersurfaces and to recollapse in S3 Friedmann universes. It is conjectured that all globally hyperbolic C2 maximally extended spatially homogeneous closed universes with S3 or S2 x S1 topology and with stress-energy tensors obeying the strong-energy, positive-pressure, dominant-energy, and matter-regularity conditions do expand from an all-encompassing initial singularity to a maximal hypersurface and then recollapse to an all-encompassing final singularity.

  5. Field induced domain switching as the origin of anomalous lattice strain along non-polar direction in rhombohedral BiScO{sub 3}-PbTiO{sub 3} close to the morphotropic phase boundary

    SciTech Connect

    Lalitha, K. V.; Ranjan, Rajeev; Fancher, Chris M.; Jones, Jacob L.

    2015-08-03

    The lattice strain and domain switching behavior of xBiScO{sub 3}–(1-x)PbTiO{sub 3} (x = 0.40) was investigated as a function of cyclic field and grain orientation by in situ X-ray diffraction during application of electric fields. The electric field induced 200 lattice strain was measured to be five times larger than the 111 lattice strain in pseudorhombohedral xBiScO{sub 3}–(1-x)PbTiO{sub 3} (x = 0.40). It is shown that the anomalous 200 lattice strain is not an intrinsic phenomenon, but arises primarily due to stress associated with the reorientation of the 111 domains in dense polycrystalline ceramic.

  6. Bi-directional streaming of solar wind electrons greater than 80 eV - ISEE evidence for a closed-field structure within the driver gas of an interplanetary shock

    NASA Technical Reports Server (NTRS)

    Bame, S. J.; Asbridge, J. R.; Feldman, W. C.; Gosling, J. T.; Zwickl, R. D.

    1981-01-01

    In near time coincidence with the arrival of helium enriched plasma driving the shock wave disturbance of November 12-13, 1978, strong bi-directional streaming of solar wind electrons greater than about 80 eV was observed with Los Alamos instrumentation on ISEE 3. The streaming persisted for many hours simultaneously parallel and anti-parallel to the interplanetary magnetic field which was directed roughly perpendicular to the sun-satellite line. This example of bidirectional streaming cannot be explained by field line connection to the earth's bow shock or the outward propagating interplanetary shock which passed ISEE 3 approximately 16 hours earlier. The event is explained if the local interplanetary field was a part of a magnetic bottle rooted at the sun or a disconnected loop propagating outward.

  7. Trajectories in Close Proximity to Asteroids

    NASA Technical Reports Server (NTRS)

    Scheeres, D. J.

    2000-01-01

    Spacecraft motion in close proximity to irregularly shaped, rotating bodies such as asteroids presents a unique dynamical environment as compared to most space missions. There are several fundamental novelties in this environment that spacecraft must deal with. These include the possibility of orbital instabilities that can act over very short time spans (on the order of hours for some systems), possible non-uniform rotation of the central gravity field, divergence of traditional gravity field representations when close to the asteroid surface, dominance of perturbing forces, an extremely large asteroid model parameter space that must be prepared for in the absence of reliable information, and the possibility of employing new and novel trajectory control techniques such as hovering and repeated landings on the asteroid surface. An overview of how these novelties impact the space of feasible close proximity operations and how different asteroid model properties will affect their implementation is given. In so doing, four fundamental types of close proximity operations will be defined. Listed in order of increasing technical difficulty these are: (1) close, stable orbits; (2) low-altitude flyovers; (3) landing trajectories; and (4) hovering trajectories. The feasibility and difficulty of implementing these operations will vary as a function of the asteroid shape, size, density, and rotation properties, and as a function of the spacecraft navigation capability. Additional information is contained in the original extended abstract.

  8. The closed fuel cycle

    SciTech Connect

    Froment, Antoine; Gillet, Philippe

    2007-07-01

    Available in abstract form only. Full text of publication follows: The fast growth of the world's economy coupled with the need for optimizing use of natural resources, for energy security and for climate change mitigation make energy supply one of the 21. century most daring challenges. The high reliability and efficiency of nuclear energy, its competitiveness in an energy market undergoing a new oil shock are as many factors in favor of the 'renaissance' of this greenhouse gas free energy. Over 160,000 tHM of LWR1 and AGR2 Used Nuclear Fuel (UNF) have already been unloaded from the reactor cores corresponding to 7,000 tons discharged per year worldwide. By 2030, this amount could exceed 400,000 tHM and annual unloading 14,000 tHM/year. AREVA believes that closing the nuclear fuel cycle through the treatment and recycling of Used Nuclear Fuel sustains the worldwide nuclear power expansion. It is an economically sound and environmentally responsible choice, based on the preservation of natural resources through the recycling of used fuel. It furthermore provides a safe and secure management of wastes while significantly minimizing the burden left to future generations. (authors)

  9. Close to the Sky

    NASA Astrophysics Data System (ADS)

    2007-11-01

    Today, a new ALMA outreach and educational book was publicly presented to city officials of San Pedro de Atacama in Chile, as part of the celebrations of the anniversary of the Andean village. ESO PR Photo 50a/07 ESO PR Photo 50a/07 A Useful Tool for Schools Entitled "Close to the sky: Biological heritage in the ALMA area", and edited in English and Spanish by ESO in Chile, the book collects unique on-site observations of the flora and fauna of the ALMA region performed by experts commissioned to investigate it and to provide key initiatives to protect it. "I thank the ALMA project for providing us a book that will surely be a good support for the education of children and youngsters of San Pedro de Atacama. Thanks to this publication, we expect our rich flora and fauna to be better known. I invite teachers and students to take advantage of this educational resource, which will be available in our schools", commented Ms. Sandra Berna, the Mayor of San Pedro de Atacama, who was given the book by representatives of the ALMA global collaboration project. Copies of the book 'Close to the sky' will be donated to all schools in the area, as a contribution to the education of students and young people in northern Chile. "From the very beginning of the project, ALMA construction has had a firm commitment to environment and local culture, protecting unique flora and fauna species and preserving old estancias belonging to the Likan Antai culture," said Jacques Lassalle, who represented ALMA at the hand-over. "Animals like the llama, the fox or the condor do not only live in the region where ALMA is now being built, but they are also key elements of the ancient Andean constellations. In this sense they are part of the same sky that will be explored by ALMA in the near future." ESO PR Photo 50c/07 ESO PR Photo 50c/07 Presentation of the ALMA book The ALMA Project is a giant, international observatory currently under construction on the high-altitude Chajnantor site in Chile

  10. Closing in on Jupiter

    NASA Image and Video Library

    2016-06-16

    On June 16, NASA discussed the status of its Juno mission to Jupiter during a news briefing at the agency’s headquarters, in Washington DC. This Fourth of July, the solar-powered Juno spacecraft will arrive at our solar system’s most massive planet after an almost five-year journey. Once in Jupiter’s orbit, the spacecraft will circle the Jovian world 37 times during 20 months, skimming to within 3,100 miles (5,000 kilometers) above the cloud tops. This is the first time a spacecraft will orbit the poles of Jupiter, providing new answers to ongoing mysteries about the planet’s core, composition and magnetic fields.

  11. Close Reading in Elementary Schools

    ERIC Educational Resources Information Center

    Fisher, Douglas; Frey, Nancy

    2012-01-01

    Close reading is a recommended instructional approach to meet the challenges of teaching complex texts. But close readings are more common in high school and college than in elementary schools. In this article, we identify the components of close reading that were developed after a group of elementary school teachers observed their colleges in…

  12. Closing in on Phoebe

    NASA Image and Video Library

    2004-06-09

    The Cassini spacecraft is closing in fast on its first target of observation in the Saturn system: the small, mysterious moon Phoebe, only 220 kilometers (137 miles) across. The three images shown here, the latest of which is twice as good as any image returned by the Voyager 2 spacecraft in 1981, were captured in the past week on approach to this outer moon of Saturn. Phoebe's surface is already showing a great deal of contrast, most likely indicative of topography, such as tall sunlit peaks and deep shadowy craters, as well as genuine variation in the reflectivity of its surface materials. Left to right, the three views were captured at a phase (Sun-Saturn-spacecraft) angle of 87 degrees between June 4 and June 7, from distances ranging from 4.1 million kilometers (2.6 million miles) to 2.5 million kilometers (1.5 million miles). The image scale ranges from 25 to 15 kilometers per pixel. Phoebe rotates once every nine hours and 16 minutes; each of these images shows a different region on Phoebe. Phoebe was the discovered in 1898. It has a very dark surface. Cassini's powerful cameras will provide the best-ever look at this moon on Friday, June 11, when the spacecraft will streak past Phoebe at a distance of only about 2,000 kilometers (1,240 miles) from the moon's surface. The current images, and the presence of large craters, promise a heavily cratered surface which will come into sharp view over the next few days when image scales should get as small as a few tens of meters. Phoebe orbits Saturn in a direction opposite to that of the larger interior Saturnian moons. Because of its small size and retrograde orbit Phoebe is believed to be a body from the distant outer solar system, perhaps one of the building blocks of the outer planets that were captured into orbit around Saturn. If true, the little moon will provide information about these primitive pieces of material. http://photojournal.jpl.nasa.gov/catalog/PIA06062

  13. Daphnis Up Close

    NASA Image and Video Library

    2017-01-18

    The wavemaker moon, Daphnis, is featured in this view, taken as NASA's Cassini spacecraft made one of its ring-grazing passes over the outer edges of Saturn's rings on Jan. 16, 2017. This is the closest view of the small moon obtained yet. Daphnis (5 miles or 8 kilometers across) orbits within the 42-kilometer (26-mile) wide Keeler Gap. Cassini's viewing angle causes the gap to appear narrower than it actually is, due to foreshortening. The little moon's gravity raises waves in the edges of the gap in both the horizontal and vertical directions. Cassini was able to observe the vertical structures in 2009, around the time of Saturn's equinox (see PIA11654). Like a couple of Saturn's other small ring moons, Atlas and Pan, Daphnis appears to have a narrow ridge around its equator and a fairly smooth mantle of material on its surface -- likely an accumulation of fine particles from the rings. A few craters are obvious at this resolution. An additional ridge can be seen further north that runs parallel to the equatorial band. Fine details in the rings are also on display in this image. In particular, a grainy texture is seen in several wide lanes which hints at structures where particles are clumping together. In comparison to the otherwise sharp edges of the Keeler Gap, the wave peak in the gap edge at left has a softened appearance. This is possibly due to the movement of fine ring particles being spread out into the gap following Daphnis' last close approach to that edge on a previous orbit. A faint, narrow tendril of ring material follows just behind Daphnis (to its left). This may have resulted from a moment when Daphnis drew a packet of material out of the ring, and now that packet is spreading itself out. The image was taken in visible (green) light with the Cassini spacecraft narrow-angle camera. The view was acquired at a distance of approximately 17,000 miles (28,000 kilometers) from Daphnis and at a Sun-Daphnis-spacecraft, or phase, angle of 71 degrees. Image

  14. Rotating-unbalanced-mass Devices for Scanning Balloon-borne Experiments, Free-flying Spacecraft, and Space Shuttle/space Station Experiments

    NASA Technical Reports Server (NTRS)

    Polites, Michael E.

    1990-01-01

    A new method is presented for scanning balloon-borne experiments, free-flying spacecraft, and gimballed experiments mounted to the space shuttle or the space station. It uses rotating-unbalanced-mass (RUM) devices for generating circular, line, or raster scan patterns and an auxiliary control system for target acquisition, keeping the scan centered on the target, and producing complementary motion for raster scanning. It is ideal for applications where the only possible way to accomplish the required scan is to physically scan the entire experiment or spacecraft as in x ray and gamma ray experiments. In such cases, this new method should have advantages over prior methods in terms of either power, weight, cost, performance, stability, or a combination of these.

  15. Pfeiffer-type cardiocranial syndrome: a patient with features of this condition and with an unbalanced subtelomeric rearrangement involving chromosomes 1p and 17q.

    PubMed

    McCann, Emma; Sweeney, Elizabeth; Sills, John; May, Paul; Smith, Sarah

    2006-04-01

    Pfeiffer-type cardiocranial syndrome (MIM 218450) was first delineated in 1987; several further patients have been reported confirming this as a distinct nosological entity. The aetiology of this condition remains unknown although an autosomal recessive pattern of inheritance has been suggested following the description of sib pairs. A patient is described with features of this condition including sagittal suture synostosis, growth retardation, learning difficulties, hypertelorism, low-set ears, micrognathia, congenital heart defects and genital anomalies. Telomere studies on blood and skin samples identified a de novo unbalanced rearrangement resulting in partial monosomy for 1p36.1 to pter and partial trisomy for 17q25.1 to qter. This case provides the first insight into the possible aetiology of this condition.

  16. Simulative and experimental investigation on stator winding turn and unbalanced supply voltage fault diagnosis in induction motors using Artificial Neural Networks.

    PubMed

    Lashkari, Negin; Poshtan, Javad; Azgomi, Hamid Fekri

    2015-11-01

    The three-phase shift between line current and phase voltage of induction motors can be used as an efficient fault indicator to detect and locate inter-turn stator short-circuit (ITSC) fault. However, unbalanced supply voltage is one of the contributing factors that inevitably affect stator currents and therefore the three-phase shift. Thus, it is necessary to propose a method that is able to identify whether the unbalance of three currents is caused by ITSC or supply voltage fault. This paper presents a feedforward multilayer-perceptron Neural Network (NN) trained by back propagation, based on monitoring negative sequence voltage and the three-phase shift. The data which are required for training and test NN are generated using simulated model of stator. The experimental results are presented to verify the superior accuracy of the proposed method. Copyright © 2015. Published by Elsevier Ltd.

  17. Prenatal diagnosis of a fetus with unbalanced translocation (4;13)(p16;q32) with overlapping features of Patau and Wolf-Hirschhorn syndromes.

    PubMed

    Tapper, Jill K; Zhang, Shuliu; Harirah, Hassan M; Panova, Neli I; Merryman, Linda S; Hawkins, Judy C; Lockhart, Lillian H; Gei, Alfredo B; Velagaleti, Gopalrao V N

    2002-01-01

    Wolf-Hirschhorn syndrome (WHS) and Patau syndrome are two of the most severe conditions resulting from chromosome abnormalities. WHS is caused by a deletion of 4p16, while Patau syndrome is caused by trisomy for some or all regions of chromosome 13. Though the etiologies of these syndromes differ, they share several features including pre- and postnatal growth retardation, microcephaly, cleft lip and palate, and cardiac anomalies. We present here a female fetus with deletion of 4p16 --> pter and duplication of 13q32 --> qter due to unbalanced segregation of t(4;13)(p16;q32) in the father. She displayed overlapping features of both of these syndromes on ultrasound. To the best of our knowledge, this is the first report of a fetus with both partial trisomy 13 and deletion of 4p16, the critical region for WHS.

  18. Pure distal 11q deletion without additional genomic imbalances in a female infant with Jacobsen syndrome and a de novo unbalanced reciprocal translocation.

    PubMed

    Chen, C-P; Lin, S-P; Hsu, C-H; Chern, S-R; Su, J-W; Chen, Y-J; Pan, C-W; Wang, W

    2012-01-01

    We report a neonate with pure deletion of distal 11q (11q23.3-->qter) and Jacobsen syndrome. The patient had growth restriction, petechiae, thrombocytopenia, dilation of renal pelvis, congenital heart defects, and seizures. Array comparative genomic hybridization revealed a 15.8-Mb deletion from 11q23.3 to 11q25 without genomic imbalances in other chromosomes. Cytogenetic analysis revealed a karyotype of 46,XX,der(7)(7pter-->7q32),der(11)(11pter--> 11q23.3::7q32-->7qter). The parental karyotypes were normal. This is the first report of pure distal 11q deletion without additional genomic imbalances in a patient with Jacobsen syndrome and a de novo unbalanced reciprocal translocation.

  19. Jacobsen syndrome due to an unbalanced translocation between 11q23 and 22q11.2 identified at age 40 years.

    PubMed

    Takahashi, Ikuko; Takahashi, Tsutomu; Sawada, Kenichi; Shimojima, Keiko; Yamamoto, Toshiyuki

    2012-01-01

    A woman with psychomotor developmental delay, congenital glaucoma, and distinctive facial features, and a short neck was diagnosed with Jacobsen syndrome (JBS) at age 40 years. A previously reported balanced translocation between chromosome 11 and 22 instead showed an unbalanced translocation by a microarray-based comparative hybridization analysis with the final karyotype of 46,XX,der(11)t(11;22)(q23.3;q11.21),del(22)(q11.21) dn. The breakpoint of chromosome 11 was determined to be at TECTA and not near the apolipoprotein gene cluster site or the fragile site (FRA11B), which are commonly seen in patients with t(11;22) and patients with typical 11q deletions, respectively. Although the phenotypic features of the patient, including psychomotor developmental delay, distinctive features, and mild thrombocytopenia, were consistent with JBS, congenital glaucoma, which is an uncommon finding of JBS, was the most prominent condition during her natural history.

  20. Unbalanced fermentation of glycerol in Escherichia coli via heterologous production of an electron transport chain and electrode interaction in microbial electrochemical cells.

    PubMed

    Sturm-Richter, Katrin; Golitsch, Frederik; Sturm, Gunnar; Kipf, Elena; Dittrich, André; Beblawy, Sebastian; Kerzenmacher, Sven; Gescher, Johannes

    2015-06-01

    Microbial electrochemical cells are an emerging technology for achieving unbalanced fermentations. However, organisms that can serve as potential biocatalysts for this application are limited by their narrow substrate spectrum. This study describes the reprogramming of Escherichia coli for the efficient use of anodes as electron acceptors. Electron transfer into the periplasm was accelerated by 183% via heterologous expression of the c-type cytochromes CymA, MtrA and STC from Shewanella oneidensis. STC was identified as a target for heterologous expression via a two-stage screening approach. First, mass spectroscopic analysis revealed natively expressed cytochromes in S. oneidensis. Thereafter, the corresponding genes were cloned and expressed in E. coli to quantify periplasmic electron transfer activity using methylene blue. This redox dye was further used to expand electron transfer to carbon electrode surfaces. The results demonstrate that E. coli can be reprogrammed from glycerol fermentation to respiration upon production of the new electron transport chain.

  1. Estimation of the proportion of genetically unbalanced spermatozoa in the semen of boars carrying chromosomal rearrangements using FISH on sperm nuclei

    PubMed Central

    Pinton, Alain; Ducos, Alain; Yerle, Martine

    2004-01-01

    Many chromosomal rearrangements are detected each year in France on young boars candidates for reproduction. The possible use of these animals requires a good knowledge of the potential effect of the rearrangements on the prolificacy of their mates. This effect can be estimated by an accurate determination of the rate of unbalanced spermatozoa in the semen of boars which carry the rearrangements. Indeed, these spermatozoa exhibiting normal fertilizing ability are responsible for an early embryonic mortality, and then, for a decrease of the litter sizes. The "spermFISH" technique, i.e. fluorescent in situ hybridization on decondensed sperm heads, has been used on several occasions in Man, in this perspective. In livestock species, this method was formerly used mainly for semen sexing purposes. We used it, for the first time, to estimate the rates of imbalance in the semen of four boars carrying chromosomal rearrangements: two reciprocal translocations, rcp(3;15)(q27;q13) and rcp(12;14)(q13;q21), as well as two independent cases of trisomy 18 mosaicism. The rates of unbalanced gametes were relatively high for the two reciprocal translocations (47.83% and 24.33%, respectively). These values differed from the apparent effects of the rearrangements estimated using a limited number of litters: a decrease in prolificacy of 23% (estimation obtained using the results of 6 litters) and 39% (57 litters), respectively for the 3/15 and 12/14 translocations. The imbalance rates were much lower for the trisomy mosaics (0.58% and 1.13%), suggesting a very moderate effect of this special kind of chromosomal rearrangement. PMID:14713414

  2. Spread of X inactivation on chromosome 15 is associated with a more severe phenotype in a girl with an unbalanced t(X; 15) translocation.

    PubMed

    Yeung, K S; Chee, Y Y; Luk, H M; Kan, Anita S Y; Tang, Mary H Y; Lau, Elizabeth T; Shuen, Andrew Y; Lo, Ivan F M; Chan, Kelvin Y K; Chung, Brian H Y

    2014-10-01

    We report on a baby girl with multiple congenital abnormalities, including cleft palate, intrauterine growth restriction, and double outlet right ventricle (DORV) with ventricular septal defect. She had an unbalanced chromosome translocation t (X;15) resulting in monosomy 15pter → p10 and trisomy Xq13.1 → q28. All three copies of Xq encompass the XIST gene. It is known that X chromosome inactivation could spread to the autosome part of an unbalanced translocation involving chromosome X and an autosome. To confirm the spread of X chromosome inactivation on chromosome 15, we evaluate the methylation change by the HumanMethylation450 BeadChip, a whole genome DNA methylation micorarray that includes 15,259 probes spanning 717 genes on chromosome 15. Results showed there was gain in DNA methylation of more than 20% in 586 CpG sites spanning the long arm of chromosome 15. We further examined the hypermethylated CpG sites located in CpG-island promoter, because genes subjected to X chromosome inactivation will have an increase in DNA methylation level in this region. A total of 75 sites representing 24 genes were hypermethylated. Nearly all of these probes are located in region proximal to the breakpoint, from 15q11.2 to 15q21.3 (35Mb) suggesting that X inactivation was spread to the proximal region of 15q. Gain of DNA methylation, especially in the CpG-island promoter, can result in functional inactivation of genes, and therefore could potentially worsen the phenotype of our patient.

  3. Ecuador project closes shop.

    PubMed

    1985-01-01

    The US Agency for International Development (AID) has discontinued its contraceptive social marketing project in Ecuador after 2 1/2 years without a sale. USAID had awarded a 3-year US$1.2 million grant to the program's contractor, the John Snow Public Health Group Inc. The project was run by Ecuador's national family planning association. This is only the 3rd time USAID has terminated a social marketing program since entering this field in 1973. Impediments to the program's operation included product price hikes and supply shortages as a result of teh inflation and currency devaluation in Ecuador in recent years. Government opposition to the sales of donated contraceptive supplies further set back the program. The name chosen for the condom distributed by the program, Liber, had to be changed since a company importing sanitary napkins was using the name Liberty and objected. The program's peculiar organizational structur is also considered to have played a role in the program's failure. Rather than having a single authority responsible for the program, a 2-headed organizational design was used. Program funds were controlled by the contractor, but the family planning organization managed day to day operations. Unified management has enabled programs in other countries to survive problems such as inflation, brand registration, and product and price approvals.

  4. Wetting Layers Close to Coexistence

    NASA Astrophysics Data System (ADS)

    Ripple, Dean Charles

    A substrate immersed in a two component liquid mixture will preferentially adsorb one of the components. I describe in this thesis theoretical and experimental results on the smooth divergence of the thickness of this adsorbed layer as the system is brought close to two phase coexistence. I present a free energy functional which combines a phenomenological equation of state suitable for near critical binary liquids with a mean field treatment of bulk and surface ions. For the system carbon disulfide plus nitromethane on glass, the theory agrees well with experiment for suitable choices of theoretical parameters. Electrical conductivity measurements of the coexisting liquid phases confirm the choice of ion concentration values. By driving a stirred binary liquid mixture off coexistence with a linear temperature ramp, very small perturbations off coexistence are possible. I apply this method to the system perfluoromethylcyclohexane plus methylcyclohexane on Si wafers, measuring the adsorption with DC null ellipsometry. As the distance from coexistence decreases, the layer thickness smoothly increases and shows a crossover from adsorption dominated by the nonzero correlation length to adsorption dominated by dispersion forces, in agreement with theoretical predictions.

  5. Close binary neutron star systems

    NASA Astrophysics Data System (ADS)

    Marronetti, Pedro

    1999-12-01

    We present a method to calculate solutions to the initial value problem in (3 + 1) general relativity corresponding to binary neutron-star systems (BNS) in irrotational quasi-equilibrium orbits. The initial value equations are solved using a conformally flat spatial metric tensor. The stellar fluid dynamics corresponds to that of systems with zero vorticity in the inertial reference frame. Irrotational systems like the ones analyzed in the present work are likely to resemble the final stages of the evolution of neutron-star binaries, thus providing insights on the inspiral process. The fluid velocity is derived from the gradient of a scalar potential. A numerical program was developed to solve the elliptic equations for the metric fields and the fluid velocity potential. We discuss the different numerical techniques employed to achieve high resolution across the stellar volume, as well as the methods used to find solutions to the Poisson-like equations with their corresponding boundary conditions. We present sequences of quasi-stable circular orbits which conserve baryonic mass. These sequences mimic the time evolution of the inspiral and are obtained without solving the complex evolution equations. They also provide sets of initial value data for future time evolution codes, which should be valid very close to the final merger. We evaluate the emission of gravitational radiation during the evolution through multipole expansions methods.

  6. Experimental simulation of closed timelike curves.

    PubMed

    Ringbauer, Martin; Broome, Matthew A; Myers, Casey R; White, Andrew G; Ralph, Timothy C

    2014-06-19

    Closed timelike curves are among the most controversial features of modern physics. As legitimate solutions to Einstein's field equations, they allow for time travel, which instinctively seems paradoxical. However, in the quantum regime these paradoxes can be resolved, leaving closed timelike curves consistent with relativity. The study of these systems therefore provides valuable insight into nonlinearities and the emergence of causal structures in quantum mechanics--essential for any formulation of a quantum theory of gravity. Here we experimentally simulate the nonlinear behaviour of a qubit interacting unitarily with an older version of itself, addressing some of the fascinating effects that arise in systems traversing a closed timelike curve. These include perfect discrimination of non-orthogonal states and, most intriguingly, the ability to distinguish nominally equivalent ways of preparing pure quantum states. Finally, we examine the dependence of these effects on the initial qubit state, the form of the unitary interaction and the influence of decoherence.

  7. Experimental simulation of closed timelike curves

    NASA Astrophysics Data System (ADS)

    Ringbauer, Martin; Broome, Matthew A.; Myers, Casey R.; White, Andrew G.; Ralph, Timothy C.

    2014-06-01

    Closed timelike curves are among the most controversial features of modern physics. As legitimate solutions to Einstein’s field equations, they allow for time travel, which instinctively seems paradoxical. However, in the quantum regime these paradoxes can be resolved, leaving closed timelike curves consistent with relativity. The study of these systems therefore provides valuable insight into nonlinearities and the emergence of causal structures in quantum mechanics—essential for any formulation of a quantum theory of gravity. Here we experimentally simulate the nonlinear behaviour of a qubit interacting unitarily with an older version of itself, addressing some of the fascinating effects that arise in systems traversing a closed timelike curve. These include perfect discrimination of non-orthogonal states and, most intriguingly, the ability to distinguish nominally equivalent ways of preparing pure quantum states. Finally, we examine the dependence of these effects on the initial qubit state, the form of the unitary interaction and the influence of decoherence.

  8. Contact degeneracies of closed 2-forms

    SciTech Connect

    Zot'ev, Dmitrii B

    2007-04-30

    Consider a closed 2-form that is degenerate at the points of a hypersurface and is non-degenerate outside it. In the neighbourhood of a singularity (which is called contact under certain natural conditions) the limit behaviour of Hamiltonian fields is investigated and a canonical form of the 2-form is found (Darboux's theorem). Connections with regular Lie structures are established. Properties of integrable structures on Liouville tori containing contact degeneracies are studied. Bibliography: 16 titles.

  9. Closed inflationary universe in patch cosmology

    SciTech Connect

    Campo, Sergio del Herrera, Ramon Saavedra, Joel Labrana, Pedro

    2009-09-15

    In this paper, we study closed inflationary universe models using the Gauss-Bonnet Brane. We determine and characterize the existence of a universe with {omega}>1, with an appropriate period of inflation. We have found that this model is less restrictive in comparison with the standard approach where a scalar field is considered. We use recent astronomical observations to constrain the parameters appearing in the model.

  10. Field Campaign Guidelines

    SciTech Connect

    Voyles, J. W.; Chapman, L. A.

    2015-12-01

    This document establishes a common set of guidelines for the Atmospheric Radiation Measurement (ARM) Climate Research Facility for planning, executing, and closing out field campaigns. The steps that guide individual field campaigns are described in the Field Campaign Tracking System and are specifically tailored to meet the scope of each field campaign.

  11. Reification and the Closed Mind

    ERIC Educational Resources Information Center

    Rockwell, Mark

    2012-01-01

    What does it mean to have an open mind? Is it desirable? Are we therefore to avoid its opposite, a closed mind? How shall we proceed in producing an open mind or avoiding its opposite a closed mind? The terms open and closed are commonly used as if the meanings of the terms were clear and the expectant goods associated with being open preferred.…

  12. 24 CFR 3285.801 - Exterior close-up.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    .... All home installers must ensure that all field installed trim, windows, doors, and other openings are... DEVELOPMENT MODEL MANUFACTURED HOME INSTALLATION STANDARDS Exterior and Interior Close-Up § 3285.801 Exterior close-up. (a) Exterior siding and roofing necessary to join all sections of the home must be installed...

  13. On some Closed Magnetic Curves on a 3-torus

    NASA Astrophysics Data System (ADS)

    Munteanu, Marian Ioan; Nistor, Ana Irina

    2017-06-01

    We consider two magnetic fields on the 3-torus obtained from two different contact forms on the Euclidean 3-space and we study when their corresponding normal magnetic curves are closed. We obtain periodicity conditions analogues to those for the closed geodesics on the torus.

  14. University Language Policies and Language Choice among Ph.D. Graduates in Estonia: The (Unbalanced) Interplay between English and Estonian

    ERIC Educational Resources Information Center

    Soler-Carbonell, Josep

    2014-01-01

    The role of English as a global language and its consequences for the internationalization of higher education are matters that have increasingly drawn the attention of researchers from different fields of language and communication. In this paper, an overview of the situation in Estonia is presented. The Estonian context has not previously been…

  15. School Closings Policy. Issue Brief

    ERIC Educational Resources Information Center

    Research For Action, 2013

    2013-01-01

    The nation's largest school districts have increasingly turned to building closures to address budget deficits, demographic shifts, and the movement of students to charter schools. Over the past decade, 70 large or mid-sized cities closed schools--averaging 11 buildings per closure. This trend shows no signs of slowing. Washington, D.C. closed 23…

  16. Lightweight Valve Closes Duct Quickly

    NASA Technical Reports Server (NTRS)

    Fournier, Walter L.; Burgy, N. Frank

    1991-01-01

    Expanding balloon serves as lightweight emergency valve to close wide duct. Uninflated balloon stored in housing of duct. Pad resting on burst diaphragm protects balloon from hot gases in duct. Once control system triggers valve, balloon inflates rapidly to block duct. Weighs much less than does conventional butterfly, hot-gas, or poppet valve capable of closing duct of equal diameter.

  17. Lightweight Valve Closes Duct Quickly

    NASA Technical Reports Server (NTRS)

    Fournier, Walter L.; Burgy, N. Frank

    1991-01-01

    Expanding balloon serves as lightweight emergency valve to close wide duct. Uninflated balloon stored in housing of duct. Pad resting on burst diaphragm protects balloon from hot gases in duct. Once control system triggers valve, balloon inflates rapidly to block duct. Weighs much less than does conventional butterfly, hot-gas, or poppet valve capable of closing duct of equal diameter.

  18. Postdivorce Father-Adolescent Closeness

    ERIC Educational Resources Information Center

    Scott, Mindy E.; Booth, Alan; King, Valarie; Johnson, David R.

    2007-01-01

    Research indicates that closeness of the father-child bond following parental divorce is associated with better outcomes for children and adolescents. Unlike other investigations, this study takes a long-term developmental approach to understanding stability and change in postdivorce father-adolescent relationship closeness. Drawing on Add Health…

  19. Parental age and unbalanced Robertsonian translocations associated with Down syndrome and Patau syndrome: comparison with maternal and paternal age effects for 47, +21 and 47, +13.

    PubMed

    Hook, E B

    1984-10-01

    Data are analysed on livebirths with trisomic syndromes associated with unbalanced Robertsonian translocations born from 1968 to 1981 and reported to the New York State Chromosome Registry. The maternal ages of reported cases were compared with those of the livebirths in the general population who were born in the same year. The number of translocations studied, the mean case-control differences in years in maternal age (and the standard errors of the mean) were respectively, as follows: D/21 mutants, n = 36, -0.1 (+/- 0.9); G/21 mutants, n = 46, +1.5 (+/-0.8); D/13 mutants, n = 16, +0.6 (+/-1.5); D/21 inherited, n = 12, -1.0 (+/-1.4); G/21 inherited, n = 3, -0.3 (+/-4.4); and D/13 inherited, n = 6, +2.1 (+/-2.4). There was little change in any category if the few cases diagnosed prenatally were included. Only the value for the G/21 mutants is significantly different from zero at the 0.05 level. (The results on G/21 mutants in maternal age are consistent with an earlier Japanese report of an increase of about 2 years over the control values.) The distribution of maternal ages suggests that G/21 mutants may be produced both by maternal age-independent and maternal age-dependent components. The data on D/21 mutants, however, do not indicate the negative association with maternal age reported in Japan. Differences between this study and the Japanese study in analyses of controls may explain this slight variation. But in any event both studies reveal no evidence for an increase in maternal age for unbalanced D/21 mutant or D/21 inherited translocations associated with Down syndrome. This is evidence against the hypothesis that relaxed selection during gestation, after recognition of pregnancy, accounts for the maternal age effects of 47, +21. In comparison with the results on Robertsonian translocations, the case-control differences in maternal age in years (and the standard errors of the mean) for 47, +21 for 2148 livebirths was +4.6 (+/-0.2), and for 2354 cases

  20. To Close or Not to Close: Guantanamo Bay

    DTIC Science & Technology

    2009-04-01

    world will be the least of our worries. 15 Closing it Down Like any controversial issue, there are also arguments on the side of the... waterboarding is an acceptable interrogation technique to coerce information from detainees. He specifically mentioned his approval of this method on Khalid...weakening its influence and effectives throughout the international community. President Obama shared this sentiment and made the closing of