Sample records for closed final repository

  1. The benefits of a fast reactor closed fuel cycle in the UK

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gregg, R.; Hesketh, K.

    2013-07-01

    The work has shown that starting a fast reactor closed fuel cycle in the UK, requires virtually all of Britain's existing and future PWR spent fuel to be reprocessed, in order to obtain the plutonium needed. The existing UK Pu stockpile is sufficient to initially support only a modest SFR 'closed' fleet assuming spent fuel can be reprocessed shortly after discharge (i.e. after two years cooling). For a substantial fast reactor fleet, most Pu will have to originate from reprocessing future spent PWR fuel. Therefore, the maximum fast reactor fleet size will be limited by the preceding PWR fleet size,more » so scenarios involving fast reactors still require significant quantities of uranium ore indirectly. However, once a fast reactor fuel cycle has been established, the very substantial quantities of uranium tails in the UK would ensure there is sufficient material for several centuries. Both the short and long term impacts on a repository have been considered in this work. Over the short term, the decay heat emanating from the HLW and spent fuel will limit the density of waste within a repository. For scenarios involving fast reactors, the only significant heat bearing actinide content will be present in the final cores, resulting in a 50% overall reduction in decay energy deposited within the repository when compared with an equivalent open fuel cycle. Over the longer term, radiological dose becomes more important. Total radiotoxicity (normalised by electricity generated) is lower for scenarios with Pu recycle after 2000 years. Scenarios involving fast reactors have the lowest radiotoxicity since the quantities of certain actinides (Np, Pu and Am) eventually stabilise. However, total radiotoxicity as a measure of radiological risk does not account for differences in radionuclide mobility once in repository. Radiological dose is dominated by a small number of fission products so is therefore not affected significantly by reactor type or recycling strategy (since the fission product will primarily be a function of nuclear energy generated). However, by reprocessing spent fuel, it is possible to immobilise the fission product in a more suitable waste form that has far more superior in-repository performance. (authors)« less

  2. Closing gaps between open software and public data in a hackathon setting: User-centered software prototyping.

    PubMed

    Busby, Ben; Lesko, Matthew; Federer, Lisa

    2016-01-01

    In genomics, bioinformatics and other areas of data science, gaps exist between extant public datasets and the open-source software tools built by the community to analyze similar data types.  The purpose of biological data science hackathons is to assemble groups of genomics or bioinformatics professionals and software developers to rapidly prototype software to address these gaps.  The only two rules for the NCBI-assisted hackathons run so far are that 1) data either must be housed in public data repositories or be deposited to such repositories shortly after the hackathon's conclusion, and 2) all software comprising the final pipeline must be open-source or open-use.  Proposed topics, as well as suggested tools and approaches, are distributed to participants at the beginning of each hackathon and refined during the event.  Software, scripts, and pipelines are developed and published on GitHub, a web service providing publicly available, free-usage tiers for collaborative software development. The code resulting from each hackathon is published at https://github.com/NCBI-Hackathons/ with separate directories or repositories for each team.

  3. Final base case community analysis: Indian Springs, Nevada for the Clark County socioeconomic impact assessment of the proposed high- level nuclear waste repository at Yucca Mountain, Nevada

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    1992-06-18

    This document provides a base case description of the rural Clark County community of Indian Springs in anticipation of change associated with the proposed high-level nuclear waste repository at Yucca Mountain. As the community closest to the proposed site, Indian Springs may be seen by site characterization workers, as well as workers associated with later repository phases, as a logical place to live. This report develops and updates information relating to a broad spectrum of socioeconomic variables, thereby providing a `snapshot` or `base case` look at Indian Springs in early 1992. With this as a background, future repository-related developments maymore » be analytically separated from changes brought about by other factors, thus allowing for the assessment of the magnitude of local changes associated with the proposed repository. Given the size of the community, changes that may be considered small in an absolute sense may have relatively large impacts at the local level. Indian Springs is, in many respects, a unique community and a community of contrasts. An unincorporated town, it is a small yet important enclave of workers on large federal projects and home to employees of small- scale businesses and services. It is a rural community, but it is also close to the urbanized Las Vega Valley. It is a desert community, but has good water resources. It is on flat terrain, but it is located within 20 miles of the tallest mountains in Nevada. It is a town in which various interest groups diverge on issues of local importance, but in a sense of community remains an important feature of life. Finally, it has a sociodemographic history of both surface transience and underlying stability. If local land becomes available, Indian Springs has some room for growth but must first consider the historical effects of growth on the town and its desired direction for the future.« less

  4. Neural network-based retrieval from software reuse repositories

    NASA Technical Reports Server (NTRS)

    Eichmann, David A.; Srinivas, Kankanahalli

    1992-01-01

    A significant hurdle confronts the software reuser attempting to select candidate components from a software repository - discriminating between those components without resorting to inspection of the implementation(s). We outline an approach to this problem based upon neural networks which avoids requiring the repository administrators to define a conceptual closeness graph for the classification vocabulary.

  5. Closing gaps between open software and public data in a hackathon setting: User-centered software prototyping

    PubMed Central

    Busby, Ben; Lesko, Matthew; Federer, Lisa

    2016-01-01

    In genomics, bioinformatics and other areas of data science, gaps exist between extant public datasets and the open-source software tools built by the community to analyze similar data types.  The purpose of biological data science hackathons is to assemble groups of genomics or bioinformatics professionals and software developers to rapidly prototype software to address these gaps.  The only two rules for the NCBI-assisted hackathons run so far are that 1) data either must be housed in public data repositories or be deposited to such repositories shortly after the hackathon’s conclusion, and 2) all software comprising the final pipeline must be open-source or open-use.  Proposed topics, as well as suggested tools and approaches, are distributed to participants at the beginning of each hackathon and refined during the event.  Software, scripts, and pipelines are developed and published on GitHub, a web service providing publicly available, free-usage tiers for collaborative software development. The code resulting from each hackathon is published at https://github.com/NCBI-Hackathons/ with separate directories or repositories for each team. PMID:27134733

  6. Science is the first step to siting nuclear waste repositories

    USGS Publications Warehouse

    Neuzil, Christopher E.

    2014-01-01

    As Shaw [2014] notes, U.S. research on shale as a repository host was halted before expending anything close to the effort devoted to studying crystalline rock, salt, and - most notably - tuff at Yucca Mountain. The new political reality regarding Yucca Mountain may allow reconsideration of the decision to abandon research on shale as a repository host.

  7. The Research Library's Role in Digital Repository Services: Final Report of the ARL Digital Repository Issues Task Force

    ERIC Educational Resources Information Center

    Association of Research Libraries, 2009

    2009-01-01

    Libraries are making diverse contributions to the development of many types of digital repositories, particularly those housing locally created digital content, including new digital objects or digitized versions of locally held works. In some instances, libraries are managing a repository and its related services entirely on their own, but often…

  8. Case for retrievable high-level nuclear waste disposal

    USGS Publications Warehouse

    Roseboom, Eugene H.

    1994-01-01

    Plans for the nation's first high-level nuclear waste repository have called for permanently closing and sealing the repository soon after it is filled. However, the hydrologic environment of the proposed site at Yucca Mountain, Nevada, should allow the repository to be kept open and the waste retrievable indefinitely. This would allow direct monitoring of the repository and maintain the options for future generations to improve upon the disposal methods or use the uranium in the spent fuel as an energy resource.

  9. Final repository for Denmark's low- and intermediate level radioactive waste

    NASA Astrophysics Data System (ADS)

    Nilsson, B.; Gravesen, P.; Petersen, S. S.; Binderup, M.

    2012-12-01

    Bertel Nilsson*, Peter Gravesen, Stig A. Schack Petersen, Merete Binderup Geological Survey of Denmark and Greenland (GEUS), Øster Voldgade 10, 1350 Copenhagen, Denmark, * email address bn@geus.dk The Danish Parliament decided in 2003 that the temporal disposal of the low- and intermediate level radioactive waste at the nuclear facilities at Risø should find another location for a final repository. The Danish radioactive waste must be stored on Danish land territory (exclusive Greenland) and must hold the entire existing radioactive waste, consisting of the waste from the decommissioning of the nuclear facilities at Risø, and the radioactive waste produced in Denmark from hospitals, universities and industry. The radioactive waste is estimated to a total amount of up to 10,000 m3. The Geological Survey of Denmark and Greenland, GEUS, is responsible for the geological studies of suitable areas for the repository. The task has been to locate and recognize non-fractured Quaternary and Tertiary clays or Precambrian bedrocks with low permeability which can isolate the radioactive waste from the surroundings the coming more than 300 years. Twenty two potential areas have been located and sequential reduced to the most favorable two to three locations taking into consideration geology, hydrogeology, nature protection and climate change conditions. Further detailed environmental and geology investigations will be undertaken at the two to three potential localities in 2013 to 2015. This study together with a study of safe transport of the radioactive waste and an investigation of appropriate repository concepts in relation to geology and safety analyses will constitute the basis upon which the final decision by the Danish Parliament on repository concept and repository location. The final repository is planned to be established and in operation at the earliest 2020.

  10. Researcher-library collaborations: Data repositories as a service for researchers.

    PubMed

    Gordon, Andrew S; Millman, David S; Steiger, Lisa; Adolph, Karen E; Gilmore, Rick O

    New interest has arisen in organizing, preserving, and sharing the raw materials-the data and metadata-that undergird the published products of research. Library and information scientists have valuable expertise to bring to bear in the effort to create larger, more diverse, and more widely used data repositories. However, for libraries to be maximally successful in providing the research data management and preservation services required of a successful data repository, librarians must work closely with researchers and learn about their data management workflows. Databrary is a data repository that is closely linked to the needs of a specific scholarly community-researchers who use video as a main source of data to study child development and learning. The project's success to date is a result of its focus on community outreach and providing services for scholarly communication, engaging institutional partners, offering services for data curation with the guidance of closely involved information professionals, and the creation of a strong technical infrastructure. Databrary plans to improve its curation tools that allow researchers to deposit their own data, enhance the user-facing feature set, increase integration with library systems, and implement strategies for long-term sustainability.

  11. A performance goal-based seismic design philosophy for waste repository facilities

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hossain, Q.A.

    1994-12-31

    A performance goal-based seismic design philosophy, compatible with DOE`s present natural phenomena hazards mitigation and {open_quotes}graded approach{close_quotes} philosophy, has been proposed for high level nuclear waste repository facilities. The rationale, evolution, and the desirable features of this method have been described. Why and how the method should and can be applied to the design of a repository facility are also discussed.

  12. A perspective on the proliferation risks of plutonium mines

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lyman, E.S.

    1996-05-01

    The program of geologic disposal of spent fuel and other plutonium-containing materials is increasingly becoming the target of criticism by individuals who argue that in the future, repositories may become low-cost sources of fissile material for nuclear weapons. This paper attempts to outline a consistent framework for analyzing the proliferation risks of these so-called {open_quotes}plutonium mines{close_quotes} and putting them into perspective. First, it is emphasized that the attractiveness of plutonium in a repository as a source of weapons material depends on its accessibility relative to other sources of fissile material. Then, the notion of a {open_quotes}material production standard{close_quotes} (MPS) ismore » proposed: namely, that the proliferation risks posed by geologic disposal will be acceptable if one can demonstrate, under a number of reasonable scenarios, that the recovery of plutonium from a repository is likely to be as difficult as new production of fissile material. A preliminary analysis suggests that the range of circumstances under which current mined repository concepts would fail to meet this standard is fairly narrow. Nevertheless, a broad application of the MPS may impose severe restrictions on repository design. In this context, the relationship of repository design parameters to easy of recovery is discussed.« less

  13. 75 FR 73095 - Privacy Act of 1974; Report of New System of Records

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-29

    ... Repository'' System No. 09-70-0587. The final rule for the Medicare and Medicaid EHR Incentive Program... primary purpose of this system, called the National Level Repository or NLR, is to collect, maintain, and... Maintenance of Data in the System The National Level Repository (NLR) contains information on eligible...

  14. 75 FR 63080 - Interim Final Rule for Reporting Pre-Enactment Swap Transactions

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-14

    ... registered swap data repository (``SDR'') \\1\\ or to the Commission by the compliance date to be established... to the terms of such swaps. \\1\\ The term ``swap data repository'' is defined in Section 1a(48) of the... the date of the enactment of this subsection shall be reported to a registered swap data repository or...

  15. Research Students and the Loughborough Institutional Repository

    ERIC Educational Resources Information Center

    Pickton, Margaret; McKnight, Cliff

    2006-01-01

    This article investigates the potential role for research students in an institutional repository (IR). Face-to-face interviews with 34 research students at Loughborough University were carried out. Using a mixture of closed and open questions, the interviews explored the students' experiences and opinions of publishing, open access and the…

  16. 10 CFR 960.3-2-2-5 - Formal site nomination.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... NUCLEAR WASTE REPOSITORY Implementation Guidelines § 960.3-2-2-5 Formal site nomination. After the final... determines suitable for site characterization for the selection of a repository site, and, in so doing, he...

  17. Designing Research Services: Cross-Disciplinary Administration and the Research Lifecycle

    NASA Astrophysics Data System (ADS)

    Madden, G.

    2017-12-01

    The sheer number of technical and administrative offices involved in the research lifecycle, and the lack of shared governance and shared processes across those offices, creates challenges to the successful preservation of research outputs. Universities need a more integrated approach to the research lifecycle that allows us to: recognize a research project as it is being initiated; identify the data associated with the research project; document and track any compliance, security, access, and publication requirements associated with the research and its data; follow the research and its associated components across the research lifecycle; and finally recognize that the research has come to a close so we can trigger the various preservation, access, and communications processes that close the loop, inform the public, and promote the continued progress of science. Such an approach will require cooperation, communications, and shared workflow tools that tie together (often across many years) PIs, research design methodologists, grants offices, contract negotiators, central research administrators, research compliance specialists, desktop IT support units, server administrators, high performance computing facilities, data centers, specialized data transfer networks, institutional research repositories, institutional data repositories, and research communications groups, all of which play a significant role in the technical or administrative success of research. This session will focus on progress towards improving cross-disciplinary administrative and technical cooperation at Penn State University, with an emphasis on generalizable approaches that can be adopted elsewhere.

  18. Schematic designs for penetration seals for a reference repository in bedded salt

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kelsall, P.C.; Case, J.B.; Meyer, D.

    1982-11-01

    The isolation of radioactive wastes in geologic repositories requires that man-made penetrations such as shafts, tunnels, or boreholes are adequately sealed. This report describes schematic seal designs for a repository in bedded salt referenced to the straitigraphy of southeastern New Mexico. The designs are presented for extensive peer review and will be updated as site-specific conceptual designs when a site for a repository in salt has been selected. The principal material used in the seal system is crushed salt obtained from excavating the repository. It is anticipated that crushed salt will consolidate as the repository rooms creep close to themore » degree that mechanical and hydrologic properties will eventually match those of undisturbed, intact salt. For southeastern New Mexico salt, analyses indicate that this process will require approximately 1000 years for a seal located at the base of one of the repository shafts (where there is little increase in temperature due to waste emplacement) and approximately 400 years for a seal located in an access tunnel within the repository. Bulkheads composed of contrete or salt bricks are also included in the seal system as components which will have low permeability during the period required for salt consolidation.« less

  19. Design and application of a data-independent precursor and product ion repository.

    PubMed

    Thalassinos, Konstantinos; Vissers, Johannes P C; Tenzer, Stefan; Levin, Yishai; Thompson, J Will; Daniel, David; Mann, Darrin; DeLong, Mark R; Moseley, M Arthur; America, Antoine H; Ottens, Andrew K; Cavey, Greg S; Efstathiou, Georgios; Scrivens, James H; Langridge, James I; Geromanos, Scott J

    2012-10-01

    The functional design and application of a data-independent LC-MS precursor and product ion repository for protein identification, quantification, and validation is conceptually described. The ion repository was constructed from the sequence search results of a broad range of discovery experiments investigating various tissue types of two closely related mammalian species. The relative high degree of similarity in protein complement, ion detection, and peptide and protein identification allows for the analysis of normalized precursor and product ion intensity values, as well as standardized retention times, creating a multidimensional/orthogonal queryable, qualitative, and quantitative space. Peptide ion map selection for identification and quantification is primarily based on replication and limited variation. The information is stored in a relational database and is used to create peptide- and protein-specific fragment ion maps that can be queried in a targeted fashion against the raw or time aligned ion detections. These queries can be conducted either individually or as groups, where the latter affords pathway and molecular machinery analysis of the protein complement. The presented results also suggest that peptide ionization and fragmentation efficiencies are highly conserved between experiments and practically independent of the analyzed biological sample when using similar instrumentation. Moreover, the data illustrate only minor variation in ionization efficiency with amino acid sequence substitutions occurring between species. Finally, the data and the presented results illustrate how LC-MS performance metrics can be extracted and utilized to ensure optimal performance of the employed analytical workflows.

  20. 10 CFR 60.52 - Termination of license.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Termination of license. 60.52 Section 60.52 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES Licenses... repository: (1) That the final disposition of radioactive wastes has been made in conformance with the DOE's...

  1. Low Level Waste Conceptual Design Adaption to Poor Geological Conditions

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bell, J.; Drimmer, D.; Giovannini, A.

    2002-02-26

    Since the early eighties, several studies have been carried out in Belgium with respect to a repository for the final disposal of low-level radioactive waste (LLW). In 1998, the Belgian Government decided to restrict future investigations to the four existing nuclear sites in Belgium or sites that might show interest. So far, only two existing nuclear sites have been thoroughly investigated from a geological and hydrogeological point of view. These sites are located in the North-East (Mol-Dessel) and in the mid part (Fleurus-Farciennes) of the country. Both sites have the disadvantage of presenting poor geological and hydrogeological conditions, which aremore » rather unfavorable to accommodate a surface disposal facility for LLW. The underground of the Mol-Dessel site consists of neogene sand layers of about 180 m thick which cover a 100 meters thick clay layer. These neogene sands contain, at 20 m depth, a thin clayey layer. The groundwater level is quite close to the surface (0-2m) and finally, the topography is almost totally flat. The upper layer of the Fleurus-Farciennes site consists of 10 m silt with poor geomechanical characteristics, overlying sands (only a few meters thick) and Westphalian shales between 15 and 20 m depth. The Westphalian shales are tectonized and strongly weathered. In the past, coal seams were mined out. This activity induced locally important surface subsidence. For both nuclear sites that were investigated, a conceptual design was made that could allow any unfavorable geological or hydrogeological conditions of the site to be overcome. In Fleurus-Farciennes, for instance, the proposed conceptual design of the repository is quite original. It is composed of a shallow, buried concrete cylinder, surrounded by an accessible concrete ring, which allows permanent inspection and control during the whole lifetime of the repository. Stability and drainage systems should be independent of potential differential settlements an d subsidences. Potential radionuclides releases are controlled and have a single discharge point to the biosphere.« less

  2. Data repositories for medical education research: issues and recommendations.

    PubMed

    Schwartz, Alan; Pappas, Cleo; Sandlow, Leslie J

    2010-05-01

    The authors explore issues surrounding digital repositories with the twofold intention of clarifying their creation, structure, content, and use, and considering the implementation of a global digital repository for medical education research data sets-an online site where medical education researchers would be encouraged to deposit their data in order to facilitate the reuse and reanalysis of the data by other researchers. By motivating data sharing and reuse, investigators, medical schools, and other stakeholders might see substantial benefits to their own endeavors and to the progress of the field of medical education.The authors review digital repositories in medicine, social sciences, and education, describe the contents and scope of repositories, and present extant examples. The authors describe the potential benefits of a medical education data repository and report results of a survey of the Society for Directors of Research in Medicine Education, in which participants responded to questions about data sharing and a potential data repository. Respondents strongly endorsed data sharing, with the caveat that principal investigators should choose whether or not to share data they collect. A large majority believed that a repository would benefit their unit and the field of medical education. Few reported using existing repositories. Finally, the authors consider challenges to the establishment of such a repository, including taxonomic organization, intellectual property concerns, human subjects protection, technological infrastructure, and evaluation standards. The authors conclude with recommendations for how a medical education data repository could be successfully developed.

  3. 10 CFR 51.109 - Public hearings in proceedings for issuance of materials license with respect to a geologic...

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... waste repository at a geologic repository operations area under parts 60 and 63 of this chapter, and in... whether it is practicable to adopt, without further supplementation, the environmental impact statement... supplementation of the environmental impact statement by NRC is required, it shall file its final supplemental...

  4. 10 CFR 51.109 - Public hearings in proceedings for issuance of materials license with respect to a geologic...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... waste repository at a geologic repository operations area under parts 60 and 63 of this chapter, and in... whether it is practicable to adopt, without further supplementation, the environmental impact statement... supplementation of the environmental impact statement by NRC is required, it shall file its final supplemental...

  5. Optimizing procedures for a human genome repository. Final report, June 1, 1988--November 30, 1990

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nierman, W.C.

    1991-03-01

    Large numbers of clones will be generated during the Human Genome Project. As each is characterized, subsets will be identified which are useful to the scientific community at large. These subsets are most readily distributed through public repositories. The American Type Culture Collection (ATCC) is experienced in repository operation, but before this project had no history in managing clones and associated information in large batches instead of individually. This project permitted the ATCC to develop several procedures for automating and thus reducing the cost of characterizing, preserving, and maintaining information about clones.

  6. 76 FR 2914 - National Institute of General Medical Sciences; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-18

    ... General Medical Sciences; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory... Sciences Special Emphasis Panel; PSI Materials Repository Review. Date: February 11, 2011. Time: 2 p.m. to... General Medical Sciences, National Institutes of Health, Natcher Building, Room 3AN18K, Bethesda, MD 20892...

  7. 78 FR 72684 - National Institute of Diabetes and Digestive and Kidney Diseases; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-03

    ... Diabetes and Digestive and Kidney Diseases; Notice of Closed Meeting Pursuant to section 10(d) of the... Diabetes and Digestive and Kidney Diseases Special Emphasis Panel; PAR11-306: NIDDK Central Repositories..., Endocrinology and Metabolic Research; 93.848, Digestive Diseases and Nutrition Research; 93.849, Kidney Diseases...

  8. 76 FR 17658 - National Institute of Diabetes and Digestive and Kidney Diseases; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-30

    ... Diabetes and Digestive and Kidney Diseases; Notice of Closed Meeting Pursuant to section 10(d) of the... Diabetes and Digestive and Kidney Diseases Special Emphasis Panel; NIDDK Central Repositories Non-Renewable... and Nutrition Research; 93.849, Kidney Diseases, Urology and Hematology Research, National Institutes...

  9. 77 FR 47653 - National Institute of Diabetes and Digestive and Kidney Diseases; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-09

    ... Diabetes and Digestive and Kidney Diseases; Notice of Closed Meetings Pursuant to section 10(d) of the... Institute of Diabetes and Digestive and Kidney Diseases Special Emphasis Panel; NIDDK Sample Repositories... Institute of Diabetes and Digestive and Kidney Diseases Special Emphasis Panel; RFA DK-12-504: The...

  10. 76 FR 5390 - National Human Genome Research Institute; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-31

    ... Research Institute; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory Committee... unwarranted invasion of personal privacy. Place: National Human Genome Research Institute Special Emphasis Panel; NHGRI Sample Repository for Human Genetic Research. Date: March 3, 2011. Time: 1 p.m. to 2 p.m...

  11. High-level waste disposal, ethics and thermodynamics

    NASA Astrophysics Data System (ADS)

    Schwartz, Michael O.

    2008-06-01

    Moral philosophy applied to nuclear waste disposal can be linked to paradigmatic science. Simple thermodynamic principles tell us something about rightness or wrongness of our action. Ethical judgement can be orientated towards the chemical compatibility between waste container and geological repository. A container-repository system as close as possible to thermodynamic equilibrium is ethically acceptable. It aims at unlimited stability, similar to the stability of natural metal deposits within the Earth’s crust. The practicability of the guideline can be demonstrated.

  12. Trustworthy Digital Repositories: Building Trust the Old Fashion Way, EARNING IT.

    NASA Astrophysics Data System (ADS)

    Kinkade, D.; Chandler, C. L.; Shepherd, A.; Rauch, S.; Groman, R. C.; Wiebe, P. H.; Glover, D. M.; Allison, M. D.; Copley, N. J.; Ake, H.; York, A.

    2016-12-01

    There are several drivers increasing the importance of high quality data management and curation in today's research process (e.g., OSTP PARR memo, journal publishers, funders, academic and private institutions), and proper management is necessary throughout the data lifecycle to enable reuse and reproducibility of results. Many digital data repositories are capable of satisfying the basic management needs of an investigator looking to share their data (i.e., publish data in the public domain), but repository services vary greatly and not all provide mature services that facilitate discovery, access, and reuse of research data. Domain-specific repositories play a vital role in the data curation process by working closely with investigators to create robust metadata, perform first order QC, and assemble and publish research data. In addition, they may employ technologies and services that enable increased discovery, access, and long-term archive. However, smaller domain facilities operate in varying states of capacity and curation ability. Within this repository environment, individual investigators (driven by publishers, funders, or institutions) need to find trustworthy repositories for their data; and funders need to direct investigators to quality repositories to ensure return on their investment. So, how can one determine the best home for valuable research data? Metrics can be applied to varying aspects of data curation, and many credentialing organizations offer services that assess and certify the trustworthiness of a given data management facility. Unfortunately, many of these certifications can be inaccessible to a small repository in cost, time, or scope. Are there alternatives? This presentation will discuss methods and approaches used by the Biological and Chemical Oceanography Data Management Office (BCO-DMO; a domain-specific, intermediate digital data repository) to demonstrate trustworthiness in the face of a daunting accreditation landscape.

  13. 75 FR 57971 - National Institute of Diabetes and Digestive and Kidney Diseases; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-23

    ... Diabetes and Digestive and Kidney Diseases; Notice of Closed Meeting Pursuant to section 10(d) of the... Diabetes and Digestive and Kidney Diseases Special Emphasis Panel, Central Repositories Non-Renewable Sample Access (PAR-10-90)--Liver, Kidney, Urological Sciences. Date: October 12, 2010. Time: 2 p.m. to 4...

  14. 78 FR 72683 - National Institute of Diabetes and Digestive and Kidney Diseases; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-03

    ... Diabetes and Digestive and Kidney Diseases; Notice of Closed Meeting Pursuant to section 10(d) of the... Diabetes and Digestive and Kidney Diseases Special Emphasis Panel, PAR13-228: Biomarkers for Diabetes, Digestive, Kidney and Urologic Diseases using Repository Biosamples. Date: February 20, 2014. Time: 2:00 p.m...

  15. YUCCA MOUNTAIN: Earth-Science Issues at a Geologic Repository for High-Level Nuclear Waste

    NASA Astrophysics Data System (ADS)

    Long, Jane C. S.

    2004-05-01

    The nation has over 40,000 metric tonnes (MT) of nuclear waste destined for disposal in a geologic repository at Yucca Mountain. In this review, we highlight some of the important geoscience issues associated with the project and place them in the context of the process by which a final decision on Yucca Mountain will be made. The issues include understanding how water could infiltrate the repository, corrode the canisters, dissolve the waste, and transport it to the biosphere during a 10,000-year compliance period in a region, the Basin and Range province, that is known for seismic and volcanic activity. Although the site is considered to be "dry," a considerable amount of water is present as pore waters and as structural water in zeolites. The geochemical environment is oxidizing, and the present repository design will maintain temperatures at greater than 100°C for thousands of years. Geoscientists in this project are challenged to make unprecedented predictions about coupled thermal, hydrologic, mechanical, and geochemical processes governing the future behavior of the repository and to conduct research in a regulatory and legal environment that requires a quantitative analysis of repository performance.

  16. The Nevada initiative: A risk communication Fiasco

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Flynn, J.; Solvic, P.; Mertz, C.K.

    The U.S. Congress has designated Yucca Mountain, Nevada as the only potential site to be studied for the nation`s first high-level nuclear waste repository. People in Nevada strongly oppose the program, managed by the U.S. Department of Energy. Survey research shows that the public believes there are great risks from a repository program, in contrast to a majority of scientists who feel the risks are acceptably small. Delays in the repository program resulting in part from public opposition in Nevada have concerned the nuclear power industry, which collects the fees for the federal repository program and believes it needs themore » repository as a final disposal facility for its high-level nuclear wastes. To assist the repository program, the American Nuclear Energy Council (ANEC), an industry group, sponsored a massive advertising campaign in Nevada. The campaign attempted to assure people that the risks of a repository were small and that the repository studies should proceed. The campaign failed because its managers misunderstood the issues underlying the controversy, attempted a covert manipulation of public opinion that was revealed, and most importantly, lacked the public trust that was necessary to communicate credibly about the risks of a nuclear waste facility. This article describes the advertising campaign and its effects. The manner in which the ANEC campaign itself became a controversial public issue is reviewed. The advertising campaign is discussed as it relates to risk assessment and communication. 29 refs., 2 tabs.« less

  17. 78 FR 46358 - National Institute of Diabetes and Digestive and Kidney Diseases; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-31

    ... Diabetes and Digestive and Kidney Diseases; Notice of Closed Meetings Pursuant to section 10(d) of the... Diabetes and Digestive and Kidney Diseases Special Emphasis Panel, NIDDK Central Repositories Non-Renewable Sample Access (X01): Kidney, Urology and Hepatitis C. Date: August 16, 2013. Time: 1:00 p.m. to 4:00 p.m...

  18. 75 FR 78717 - National Institute of Diabetes and Digestive and Kidney Diseases; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-16

    ... Diabetes and Digestive and Kidney Diseases Special Emphasis Panel; Central Repositories Non-Renewable Sample Access (PAR-10-90)-Type 1 Diabetes. Date: January 24, 2011. Time: 2 p.m. to 4 p.m. Agenda: To... Diabetes and Digestive and Kidney Diseases; Notice of Closed Meetings Pursuant to section 10(d) of the...

  19. Thermal Analysis of a Nuclear Waste Repository in Argillite Host Rock

    NASA Astrophysics Data System (ADS)

    Hadgu, T.; Gomez, S. P.; Matteo, E. N.

    2017-12-01

    Disposal of high-level nuclear waste in a geological repository requires analysis of heat distribution as a result of decay heat. Such an analysis supports design of repository layout to define repository footprint as well as provide information of importance to overall design. The analysis is also used in the study of potential migration of radionuclides to the accessible environment. In this study, thermal analysis for high-level waste and spent nuclear fuel in a generic repository in argillite host rock is presented. The thermal analysis utilized both semi-analytical and numerical modeling in the near field of a repository. The semi-analytical method looks at heat transport by conduction in the repository and surroundings. The results of the simulation method are temperature histories at selected radial distances from the waste package. A 3-D thermal-hydrologic numerical model was also conducted to study fluid and heat distribution in the near field. The thermal analysis assumed a generic geological repository at 500 m depth. For the semi-analytical method, a backfilled closed repository was assumed with basic design and material properties. For the thermal-hydrologic numerical method, a repository layout with disposal in horizontal boreholes was assumed. The 3-D modeling domain covers a limited portion of the repository footprint to enable a detailed thermal analysis. A highly refined unstructured mesh was used with increased discretization near heat sources and at intersections of different materials. All simulations considered different parameter values for properties of components of the engineered barrier system (i.e. buffer, disturbed rock zone and the host rock), and different surface storage times. Results of the different modeling cases are presented and include temperature and fluid flow profiles in the near field at different simulation times. Sandia National Laboratories is a multimission laboratory managed and operated by National Technology and Engineering Solutions of Sandia, LLC., a wholly owned subsidiary of Honeywell International, Inc., for the U.S. Department of Energy's National Nuclear Security Administration under contract DE-NA-0003525. SAND2017-8295 A.

  20. Seven [Data] Habits of Highly Successful Researchers

    NASA Astrophysics Data System (ADS)

    Kinkade, D.; Shepherd, A.; Saito, M. A.; Wiebe, P. H.; Ake, H.; Biddle, M.; Copley, N. J.; Rauch, S.; Switzer, M. E.; York, A.

    2017-12-01

    Navigating the landscape of open science and data sharing can be daunting for the long-tail scientist. From satisfying funder requirements, and ensuring proper attribution for their work, to determining the best repository for data management and archive, there are several facets to be considered. Yet, there is no single source of guidance for investigators who may be using multiple research funding models. What role can existing repositories play to help facilitate a more effective data sharing workflow? The Biological and Chemical Oceanographic Data Management Office (BCO-DMO) is a domain-specific repository occupying the niche between funder and investigator. The office works closely with its stakeholders to develop and provide guidance, services, and tools that assist researchers in meeting their data sharing needs. From determining if BCO-DMO is the appropriate repository to manage an investigator's project data, to ensuring that investigator is able to fulfill funder requirements. The goal is to relieve the investigator of the more difficult aspects of data management and data sharing, while simultaneously educating them in better data management practices that will streamline the process of conducting open research in the future. This presentation will provide an overview of the BCO-DMO repository, highlighting some of the services and guidance the office provides to its community.

  1. Evaluation of Five Sedimentary Rocks Other Than Salt for Geologic Repository Siting Purposes

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Croff, A.G.; Lomenick, T.F.; Lowrie, R.S.

    The US Department of Energy (DOE), in order to increase the diversity of rock types under consideration by the geologic disposal program, initiated the Sedimary ROck Program (SERP), whose immediate objectiv eis to evaluate five types of secimdnary rock - sandstone, chalk, carbonate rocks (limestone and dolostone), anhydrock, and shale - to determine the potential for siting a geologic repository. The evaluation of these five rock types, together with the ongoing salt studies, effectively results in the consideration of all types of relatively impermeable sedimentary rock for repository purposes. The results of this evaluation are expressed in terms of amore » ranking of the five rock types with respect to their potential to serve as a geologic repository host rock. This comparative evaluation was conducted on a non-site-specific basis, by use of generic information together with rock evaluation criteria (RECs) derived from the DOE siting guidelines for geologic repositories (CFR 1984). An information base relevant to rock evaluation using these RECs was developed in hydrology, geochemistry, rock characteristics (rock occurrences, thermal response, rock mechanics), natural resources, and rock dissolution. Evaluation against postclosure and preclosure RECs yielded a ranking of the five subject rocks with respect to their potential as repository host rocks. Shale was determined to be the most preferred of the five rock types, with sandstone a distant second, the carbonate rocks and anhydrock a more distant third, and chalk a relatively close fourth.« less

  2. The JRC Nanomaterials Repository: A unique facility providing representative test materials for nanoEHS research.

    PubMed

    Totaro, Sara; Cotogno, Giulio; Rasmussen, Kirsten; Pianella, Francesca; Roncaglia, Marco; Olsson, Heidi; Riego Sintes, Juan M; Crutzen, Hugues P

    2016-11-01

    The European Commission has established a Nanomaterials Repository that hosts industrially manufactured nanomaterials that are distributed world-wide for safety testing of nanomaterials. In a first instance these materials were tested in the OECD Testing Programme. They have then also been tested in several EU funded research projects. The JRC Repository of Nanomaterials has thus developed into serving the global scientific community active in the nanoEHS (regulatory) research. The unique Repository facility is a state-of-the-art installation that allows customised sub-sampling under the safest possible conditions, with traceable final sample vials distributed world-wide for research purposes. This paper describes the design of the Repository to perform a semi-automated subsampling procedure, offering high degree of flexibility and precision in the preparation of NM vials for customers, while guaranteeing the safety of the operators, and environmental protection. The JRC nanomaterials are representative for part of the world NMs market. Their wide use world-wide facilitates the generation of comparable and reliable experimental results and datasets in (regulatory) research by the scientific community, ultimately supporting the further development of the OECD regulatory test guidelines. Copyright © 2016 The Authors. Published by Elsevier Inc. All rights reserved.

  3. Object links in the repository

    NASA Technical Reports Server (NTRS)

    Beck, Jon; Eichmann, David

    1991-01-01

    Some of the architectural ramifications of extending the Eichmann/Atkins lattice-based classification scheme to encompass the assets of the full life-cycle of software development are explored. In particular, we wish to consider a model which provides explicit links between objects in addition to the edges connecting classification vertices in the standard lattice. The model we consider uses object-oriented terminology. Thus, the lattice is viewed as a data structure which contains class objects which exhibit inheritance. A description of the types of objects in the repository is presented, followed by a discussion of how they interrelate. We discuss features of the object-oriented model which support these objects and their links, and consider behavior which an implementation of the model should exhibit. Finally, we indicate some thoughts on implementing a prototype of this repository architecture.

  4. Proteomics data exchange and storage: the need for common standards and public repositories.

    PubMed

    Jiménez, Rafael C; Vizcaíno, Juan Antonio

    2013-01-01

    Both the existence of data standards and public databases or repositories have been key factors behind the development of the existing "omics" approaches. In this book chapter we first review the main existing mass spectrometry (MS)-based proteomics resources: PRIDE, PeptideAtlas, GPMDB, and Tranche. Second, we report on the current status of the different proteomics data standards developed by the Proteomics Standards Initiative (PSI): the formats mzML, mzIdentML, mzQuantML, TraML, and PSI-MI XML are then reviewed. Finally, we present an easy way to query and access MS proteomics data in the PRIDE database, as a representative of the existing repositories, using the workflow management system (WMS) tool Taverna. Two different publicly available workflows are explained and described.

  5. Implementing and Sustaining Data Lifecycle best Practices: a Framework for Researchers and Repositories

    NASA Astrophysics Data System (ADS)

    Stall, S.

    2016-02-01

    Emerging data management mandates in conjunction with cross-domain international interoperability are posing new challenges for researchers and repositories. Domain repositories are serving in this critical, growing role monitoring and leading data management standards and capability within their own repository and working on mappings between repositories internationally. Leading research institutions and companies will also be important as they develop and expand data curation efforts. This landscape poses a number of challenges for developing and ensuring the use of best practices in curating research data, enabling discovery, elevating quality across diverse repositories, and helping researchers collect and organize it through the full data life cycle. This multidimensional challenge will continue to grow in complexity. The American Geophysical Union (AGU) is developing two programs to help researchers and data repositories develop and elevate best practices and address these challenges. The goal is to provide tools for the researchers and repositories, whether domain, institutional, or other, that improve performance throughout the data lifecycle across the Earth and space science community. For scientists and researchers, AGU is developing courses around handling data that can lead toward a certification in geoscience data management. Course materials will cover metadata management and collection, data analysis, integration of data, and data presentation. The course topics are being finalized by the advisory board with the first one planned to be available later this year. AGU is also developing a program aimed at helping data repositories, large and small, domain-specific to general, assess and improve data management practices. AGU has partnered with the CMMI® Institute to adapt their Data Management Maturity (DMM)SM framework within the Earth and space sciences. A data management assessment using the DMMSM involves identifying accomplishments and weaknesses compared to leading practices for data management. Recommendations can help improve quality and consistency across the community that will facilitate reuse in the data lifecycle. Through governance, quality, and architecture process areas the assessment can measure the ability for data to be discoverable and interoperable.

  6. 78 FR 45937 - Final Flood Hazard Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-30

    ... repository Community address Mason County, West Virginia, and Incorporated Areas Docket No.: FEMA-B-1270 City..., 133 2nd Street, Hartford, WV 25247. Town of Henderson Town Hall, 1 Railroad Street, Henderson, WV...

  7. Environmental assessment: Reference repository location, Hanford site, Washington

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    none,

    1986-05-01

    In February 1983, the US Department of Energy (DOE) identified a reference repository location at the Hanford Site in Washington as one of the nine potentially acceptable sites for a mined geologic repository for spent nuclear fuel and high-level radioactive waste. The site is in the Columbia Plateau, which is one of five distinct geohydrologic settings considered for the first repository. To determine their suitability, the Hanford Site and the eight other potentially acceptable sites have been evaluated in accordance with the DOE's General Guidelines for the Recommendation of Sites for the Nuclear Waste Repositories. These evaluations were reported inmore » draft environmental assessments (EAs), which were issued for public review and comment. After considering the comments received on the draft EAs, the DOE prepared the final EAs. On the basis of the evaluations reported in this EA, the DOE has found that the Hanford site is not disqualified under the guidelines. The DOE has also found that it is suitable for site characterization because the evidence does not support a conclusion that the site will not be able to meet each of the qualifying conditions specified in the guidelines. On the basis of these findings, the DOE is nominating the Hanford site as one of five sites suitable for characterization.« less

  8. Modeling transient heat transfer in nuclear waste repositories.

    PubMed

    Yang, Shaw-Yang; Yeh, Hund-Der

    2009-09-30

    The heat of high-level nuclear waste may be generated and released from a canister at final disposal sites. The waste heat may affect the engineering properties of waste canisters, buffers, and backfill material in the emplacement tunnel and the host rock. This study addresses the problem of the heat generated from the waste canister and analyzes the heat distribution between the buffer and the host rock, which is considered as a radial two-layer heat flux problem. A conceptual model is first constructed for the heat conduction in a nuclear waste repository and then mathematical equations are formulated for modeling heat flow distribution at repository sites. The Laplace transforms are employed to develop a solution for the temperature distributions in the buffer and the host rock in the Laplace domain, which is numerically inverted to the time-domain solution using the modified Crump method. The transient temperature distributions for both the single- and multi-borehole cases are simulated in the hypothetical geological repositories of nuclear waste. The results show that the temperature distributions in the thermal field are significantly affected by the decay heat of the waste canister, the thermal properties of the buffer and the host rock, the disposal spacing, and the thickness of the host rock at a nuclear waste repository.

  9. Modelling of processes occurring in deep geological repository - Development of new modules in the GoldSim environment

    NASA Astrophysics Data System (ADS)

    Vopálka, D.; Lukin, D.; Vokál, A.

    2006-01-01

    Three new modules modelling the processes that occur in a deep geological repository have been prepared in the GoldSim computer code environment (using its Transport Module). These modules help to understand the role of selected parameters in the near-field region of the final repository and to prepare an own complex model of the repository behaviour. The source term module includes radioactive decay and ingrowth in the canister, first order degradation of fuel matrix, solubility limitation of the concentration of the studied nuclides, and diffusive migration through the surrounding bentonite layer controlled by the output boundary condition formulated with respect to the rate of water flow in the rock. The corrosion module describes corrosion of canisters made of carbon steel and transport of corrosion products in the near-field region. This module computes balance equations between dissolving species and species transported by diffusion and/or advection from the surface of a solid material. The diffusion module that includes also non-linear form of the interaction isotherm can be used for an evaluation of small-scale diffusion experiments.

  10. Implementation of the Brazilian National Repository - RBMN Project - 13008

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cassia Oliveira de Tello, Cledola

    2013-07-01

    Ionizing radiation in Brazil is used in electricity generation, medicine, industry, agriculture and for research and development purposes. All these activities can generate radioactive waste. At this point, in Brazil, the use of nuclear energy and radioisotopes justifies the construction of a national repository for radioactive wastes of low and intermediate-level. According to Federal Law No. 10308, Brazilian National Commission for Nuclear Energy (CNEN) is responsible for designing and constructing the intermediate and final storages for radioactive wastes. Additionally, a restriction on the construction of Angra 3 is that the repository is under construction until its operation start, attaining somemore » requirements of the Brazilian Environmental Regulator (IBAMA). Besides this NPP, in the National Energy Program is previewed the installation of four more plants, by 2030. In November 2008, CNEN launched the Project RBMN (Repository for Low and Intermediate-Level Radioactive Wastes), which aims at the implantation of a National Repository for disposal of low and intermediate-level of radiation wastes. This Project has some aspects that are unique in the Brazilian context, especially referring to the time between its construction and the end of its institutional period. This time is about 360 years, when the area will be released for unrestricted uses. It means that the Repository must be safe and secure for more than three hundred years, which is longer than half of the whole of Brazilian history. This aspect is very new for the Brazilian people, bringing a new dimension to public acceptance. Another point is this will be the first repository in South America, bringing a real challenge for the continent. The current status of the Project is summarized. (authors)« less

  11. Temperature-package power correlations for open-mode geologic disposal concepts.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hardin, Ernest.

    2013-02-01

    Logistical simulation of spent nuclear fuel (SNF) management in the U.S. combines storage, transportation and disposal elements to evaluate schedule, cost and other resources needed for all major operations leading to final geologic disposal. Geologic repository reference options are associated with limits on waste package thermal power output at emplacement, in order to meet limits on peak temperature for certain key engineered and natural barriers. These package power limits are used in logistical simulation software such as CALVIN, as threshold requirements that must be met by means of decay storage or SNF blending in waste packages, before emplacement in amore » repository. Geologic repository reference options include enclosed modes developed for crystalline rock, clay or shale, and salt. In addition, a further need has been addressed for open modes in which SNF can be emplaced in a repository, then ventilated for decades or longer to remove heat, prior to permanent repository closure. For each open mode disposal concept there are specified durations for surface decay storage (prior to emplacement), repository ventilation, and repository closure operations. This study simulates those steps for several timing cases, and for SNF with three fuel-burnup characteristics, to develop package power limits at which waste packages can be emplaced without exceeding specified temperature limits many years later after permanent closure. The results are presented in the form of correlations that span a range of package power and peak postclosure temperature, for each open-mode disposal concept, and for each timing case. Given a particular temperature limit value, the corresponding package power limit for each case can be selected for use in CALVIN and similar tools.« less

  12. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Harmon, K.M.; Lakey, L.T.; Leigh, I.W.

    Worldwide activities related to nuclear fuel cycle and radioactive waste management programs are summarized. Several trends have developed in waste management strategy: All countries having to dispose of reprocessing wastes plan on conversion of the high-level waste (HLW) stream to a borosilicate glass and eventual emplacement of the glass logs, suitably packaged, in a deep geologic repository. Countries that must deal with plutonium-contaminated waste emphasize pluonium recovery, volume reduction and fixation in cement or bitumen in their treatment plans and expect to use deep geologic repositories for final disposal. Commercially available, classical engineering processing are being used worldwide to treatmore » and immobilize low- and intermediate-level wastes (LLW, ILW); disposal to surface structures, shallow-land burial and deep-underground repositories, such as played-out mines, is being done widely with no obvious technical problems. Many countries have established extensive programs to prepare for construction and operation of geologic repositories. Geologic media being studied fall into three main classes: argillites (clay or shale); crystalline rock (granite, basalt, gneiss or gabbro); and evaporates (salt formations). Most nations plan to allow 30 years or longer between discharge of fuel from the reactor and emplacement of HLW or spent fuel is a repository to permit thermal and radioactive decay. Most repository designs are based on the mined-gallery concept, placing waste or spent fuel packages into shallow holes in the floor of the gallery. Many countries have established extensive and costly programs of site evaluation, repository development and safety assessment. Two other waste management problems are the subject of major R and D programs in several countries: stabilization of uranium mill tailing piles; and immobilization or disposal of contaminated nuclear facilities, namely reactors, fuel cycle plants and R and D laboratories.« less

  13. 75 FR 71133 - National Institute of Mental Health; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-22

    ... Emphasis Panel; Competitive Revision for Stem Cell Repository Relevant to Mental Disorders. Date: December... Domestic Assistance Program Nos. 93.242, Mental Health Research Grants; 93.281, Scientist Development Award, Scientist Development Award for Clinicians, and Research Scientist Award; 93.282, Mental Health National...

  14. Projected environmental impacts of radioactive material transportation to the first US repository site

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Neuhauser, K.S.; Cashwell, J.W.; Reardon, P.C.

    1986-12-31

    This paper discusses the relative national environmental impacts of transporting nuclear wastes to each of the nine candidate repository sites in the United States. Several of the potential sites are closely clustered and, for the purpose of distance and routing calculations, are treated as a single location. These are: Cypress Creek Dome and Richton Dome in Mississippi (Gulf Interior Region), Deaf Smith County and Swisher County sites in Texas (Permian Basin), and Davis Canyon and Lavender Canyon site in Utah (Paradox Basin). The remaining sites are: Vacherie Dome, Louisiana; Yucca Mountain, Nevada; and Hanford Reservation, Washington. For compatibility with bothmore » the repository system authorized by the NWPA and with the MRS option, two separate scenarios were analyzed. In belief, they are (1) shipment of spent fuel and high-level wastes (HLW) directly from waste generators to a repository (Reference Case) and (2) shipment of spent fuel to a Monitored Retrievable Storage (MRS) facility and then to a repository. Between 17 and 38 truck accident fatalities, between 1.4 and 7.7 rail accident fatalities, and between 0.22 and 12 radiological health effects can be expected to occur as a result of radioactive material transportation during the 26-year operating period of the first repository. During the same period in the United States, about 65,000 total deaths from truck accidents and about 32,000 total deaths from rail accidents would occur; also an estimated 58,300 cancer fatalities are predicted to occur in the United States during a 26-year period from exposure to background radiation alone (not including medical and other manmade sources). The risks reported here are upper limits and are small by comparison with the "natural background" of risks of the same type. 3 refs., 6 tabs.« less

  15. Disposal of spent fuel

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Blomeke, J O; Ferguson, D E; Croff, A G

    1978-01-01

    Based on preliminary analyses, spent fuel assemblies are an acceptable form for waste disposal. The following studies appear necessary to bring our knowledge of spent fuel as a final disposal form to a level comparable with that of the solidified wastes from reprocessing: 1. A complete systems analysis is needed of spent fuel disposition from reactor discharge to final isolation in a repository. 2. Since it appears desirable to encase the spent fuel assembly in a metal canister, candidate materials for this container need to be studied. 3. It is highly likely that some ''filler'' material will be needed betweenmore » the fuel elements and the can. 4. Leachability, stability, and waste-rock interaction studies should be carried out on the fuels. The major disadvantages of spent fuel as a disposal form are the lower maximum heat loading, 60 kW/acre versus 150 kW/acre for high-level waste from a reprocessing plant; the greater long-term potential hazard due to the larger quantities of plutonium and uranium introduced into a repository; and the possibility of criticality in case the repository is breached. The major advantages are the lower cost and increased near-term safety resulting from eliminating reprocessing and the treatment and handling of the wastes therefrom.« less

  16. Analog earthquakes

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hofmann, R.B.

    1995-09-01

    Analogs are used to understand complex or poorly understood phenomena for which little data may be available at the actual repository site. Earthquakes are complex phenomena, and they can have a large number of effects on the natural system, as well as on engineered structures. Instrumental data close to the source of large earthquakes are rarely obtained. The rare events for which measurements are available may be used, with modfications, as analogs for potential large earthquakes at sites where no earthquake data are available. In the following, several examples of nuclear reactor and liquified natural gas facility siting are discussed.more » A potential use of analog earthquakes is proposed for a high-level nuclear waste (HLW) repository.« less

  17. Proteomics data repositories: Providing a safe haven for your data and acting as a springboard for further research

    PubMed Central

    Vizcaíno, Juan Antonio; Foster, Joseph M.; Martens, Lennart

    2010-01-01

    Despite the fact that data deposition is not a generalised fact yet in the field of proteomics, several mass spectrometry (MS) based proteomics repositories are publicly available for the scientific community. The main existing resources are: the Global Proteome Machine Database (GPMDB), PeptideAtlas, the PRoteomics IDEntifications database (PRIDE), Tranche, and NCBI Peptidome. In this review the capabilities of each of these will be described, paying special attention to four key properties: data types stored, applicable data submission strategies, supported formats, and available data mining and visualization tools. Additionally, the data contents from model organisms will be enumerated for each resource. There are other valuable smaller and/or more specialized repositories but they will not be covered in this review. Finally, the concept behind the ProteomeXchange consortium, a collaborative effort among the main resources in the field, will be introduced. PMID:20615486

  18. DOE Office of Scientific and Technical Information (OSTI.GOV)

    W. L. Poe, Jr.; P.F. Wise

    The U.S. Department of Energy (DOE) is preparing a proposal to construct, operate 2nd monitor, and eventually close a repository at Yucca Mountain in Nye County, Nevada, for the geologic disposal of spent nuclear fuel (SNF) and high-level radioactive waste (HLW). As part of this effort, DOE has prepared a viability assessment and an assessment of potential consequences that may exist if the repository is not constructed. The assessment of potential consequences if the repository is not constructed assumes that all SNF and HLW would be left at the generator sites. These include 72 commercial generator sites (three commercial facilitymore » pairs--Salem and Hope Creek, Fitzpatrick and Nine Mile Point, and Dresden and Morris--would share common storage due to their close proximity to each other) and five DOE sites across the country. DOE analyzed the environmental consequences of the effects of the continued storage of these materials at these sites in a report titled Continued Storage Analysis Report (CSAR; Reference 1 ) . The CSAR analysis includes a discussion of the degradation of these materials when exposed to the environment. This document describes the environmental parameters that influence the degradation analyzed in the CSAR. These include temperature, relative humidity, precipitation chemistry (pH and chemical composition), annual precipitation rates, annual number of rain-days, and annual freeze/thaw cycles. The document also tabulates weather conditions for each storage site, evaluates the degradation of concrete storage modules and vaults in different regions of the country, and provides a thermal analysis of commercial SNF in storage.« less

  19. Multi-scale groundwater flow modeling during temperate climate conditions for the safety assessment of the proposed high-level nuclear waste repository site at Forsmark, Sweden

    NASA Astrophysics Data System (ADS)

    Joyce, Steven; Hartley, Lee; Applegate, David; Hoek, Jaap; Jackson, Peter

    2014-09-01

    Forsmark in Sweden has been proposed as the site of a geological repository for spent high-level nuclear fuel, to be located at a depth of approximately 470 m in fractured crystalline rock. The safety assessment for the repository has required a multi-disciplinary approach to evaluate the impact of hydrogeological and hydrogeochemical conditions close to the repository and in a wider regional context. Assessing the consequences of potential radionuclide releases requires quantitative site-specific information concerning the details of groundwater flow on the scale of individual waste canister locations (1-10 m) as well as details of groundwater flow and composition on the scale of groundwater pathways between the facility and the surface (500 m to 5 km). The purpose of this article is to provide an illustration of multi-scale modeling techniques and the results obtained when combining aspects of local-scale flows in fractures around a potential contaminant source with regional-scale groundwater flow and transport subject to natural evolution of the system. The approach set out is novel, as it incorporates both different scales of model and different levels of detail, combining discrete fracture network and equivalent continuous porous medium representations of fractured bedrock.

  20. Groundwater flow modeling of periods with periglacial and glacial climate conditions for the safety assessment of the proposed high-level nuclear waste repository site at Forsmark, Sweden

    NASA Astrophysics Data System (ADS)

    Vidstrand, Patrik; Follin, Sven; Selroos, Jan-Olof; Näslund, Jens-Ove

    2014-09-01

    The impact of periglacial and glacial climate conditions on groundwater flow in fractured crystalline rock is studied by means of groundwater flow modeling of the Forsmark site, which was recently proposed as a repository site for the disposal of spent high-level nuclear fuel in Sweden. The employed model uses a thermal-hydraulically coupled approach for permafrost modeling and discusses changes in groundwater flow implied by the climate conditions found over northern Europe at different times during the last glacial cycle (Weichselian glaciation). It is concluded that discharge of particles released at repository depth occurs very close to the ice-sheet margin in the absence of permafrost. If permafrost is included, the greater part discharges into taliks in the periglacial area. During a glacial cycle, hydraulic gradients at repository depth reach their maximum values when the ice-sheet margin passes over the site; at this time, also, the interface between fresh and saline waters is distorted the most. The combined effect of advances and retreats during several glaciations has not been studied in the present work; however, the results indicate that hydrochemical conditions at depth in the groundwater flow model are almost restored after a single event of ice-sheet advance and retreat.

  1. The environmental constraint needs for design improvements to the Saligny I/LLW-repository near Cernavoda NPP

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Barariu, Gheorghe

    2007-07-01

    The paper presents the new perspectives on the development of the L/ILW Final Repository Project which will be built near Cernavoda NPP. The Repository is designed to satisfy the main performance objectives in accordance to IAEA recommendation. Starting in October 1996, Romania became a country with an operating nuclear power plant. Reactor 2 reached the criticality on May 6, 2007 and it will be put in commercial operation in September 2007. The Ministry of Economy and Finance has decided to proceed with the commissioning of Units 3 and 4 of Cernavoda NPP till 2014. The Strategy for radioactive waste managementmore » was elaborated by National Agency for Radioactive Waste (ANDRAD), the jurisdictional authority for definitive disposal and the coordination of nuclear spent fuel and radioactive waste management (Order 844/2004) with attributions established by Governmental Decision (GO) 31/2006. The Strategy specifies the commissioning of the Saligny L/IL Radwaste Repository near Cernavoda NPP in 2014. When designing the L/IL Radwaste Repository, the following prerequisites have been taken into account: 1) Cernavoda NPP will be equipped with 4 Candu 6 units. 2) National Legislation in radwaste management will be reviewed and/or completed to harmonize with UE standards 3) The selected site is now in process of confirmation after a comprehensive set of interdisciplinary investigations. (author)« less

  2. COMODI: an ontology to characterise differences in versions of computational models in biology.

    PubMed

    Scharm, Martin; Waltemath, Dagmar; Mendes, Pedro; Wolkenhauer, Olaf

    2016-07-11

    Open model repositories provide ready-to-reuse computational models of biological systems. Models within those repositories evolve over time, leading to different model versions. Taken together, the underlying changes reflect a model's provenance and thus can give valuable insights into the studied biology. Currently, however, changes cannot be semantically interpreted. To improve this situation, we developed an ontology of terms describing changes in models. The ontology can be used by scientists and within software to characterise model updates at the level of single changes. When studying or reusing a model, these annotations help with determining the relevance of a change in a given context. We manually studied changes in selected models from BioModels and the Physiome Model Repository. Using the BiVeS tool for difference detection, we then performed an automatic analysis of changes in all models published in these repositories. The resulting set of concepts led us to define candidate terms for the ontology. In a final step, we aggregated and classified these terms and built the first version of the ontology. We present COMODI, an ontology needed because COmputational MOdels DIffer. It empowers users and software to describe changes in a model on the semantic level. COMODI also enables software to implement user-specific filter options for the display of model changes. Finally, COMODI is a step towards predicting how a change in a model influences the simulation results. COMODI, coupled with our algorithm for difference detection, ensures the transparency of a model's evolution, and it enhances the traceability of updates and error corrections. COMODI is encoded in OWL. It is openly available at http://comodi.sems.uni-rostock.de/ .

  3. A Computational Workflow for the Automated Generation of Models of Genetic Designs.

    PubMed

    Misirli, Göksel; Nguyen, Tramy; McLaughlin, James Alastair; Vaidyanathan, Prashant; Jones, Timothy S; Densmore, Douglas; Myers, Chris; Wipat, Anil

    2018-06-05

    Computational models are essential to engineer predictable biological systems and to scale up this process for complex systems. Computational modeling often requires expert knowledge and data to build models. Clearly, manual creation of models is not scalable for large designs. Despite several automated model construction approaches, computational methodologies to bridge knowledge in design repositories and the process of creating computational models have still not been established. This paper describes a workflow for automatic generation of computational models of genetic circuits from data stored in design repositories using existing standards. This workflow leverages the software tool SBOLDesigner to build structural models that are then enriched by the Virtual Parts Repository API using Systems Biology Open Language (SBOL) data fetched from the SynBioHub design repository. The iBioSim software tool is then utilized to convert this SBOL description into a computational model encoded using the Systems Biology Markup Language (SBML). Finally, this SBML model can be simulated using a variety of methods. This workflow provides synthetic biologists with easy to use tools to create predictable biological systems, hiding away the complexity of building computational models. This approach can further be incorporated into other computational workflows for design automation.

  4. Environmental digital data repositories project : final report, June 22, 2009.

    DOT National Transportation Integrated Search

    2010-06-22

    This research body of work addresses two outstanding needs of the FDOT. The first need is to support the FDOT's Strategic Intermodal System (SIS) initiative and their efforts to define and manage existing and proposed multimodal centers, modes (air, ...

  5. Six methodological steps to build medical data warehouses for research.

    PubMed

    Szirbik, N B; Pelletier, C; Chaussalet, T

    2006-09-01

    We propose a simple methodology for heterogeneous data collection and central repository-style database design in healthcare. Our method can be used with or without other software development frameworks, and we argue that its application can save a relevant amount of implementation effort. Also, we believe that the method can be used in other fields of research, especially those that have a strong interdisciplinary nature. The idea emerged during a healthcare research project, which consisted among others in grouping information from heterogeneous and distributed information sources. We developed this methodology by the lessons learned when we had to build a data repository, containing information about elderly patients flows in the UK's long-term care system (LTC). We explain thoroughly those aspects that influenced the methodology building. The methodology is defined by six steps, which can be aligned with various iterative development frameworks. We describe here the alignment of our methodology with the RUP (rational unified process) framework. The methodology emphasizes current trends, as early identification of critical requirements, data modelling, close and timely interaction with users and stakeholders, ontology building, quality management, and exception handling. Of a special interest is the ontological engineering aspect, which had the effects with the highest impact after the project. That is, it helped stakeholders to perform better collaborative negotiations that brought better solutions for the overall system investigated. An insight into the problems faced by others helps to lead the negotiators to win-win situations. We consider that this should be the social result of any project that collects data for better decision making that leads finally to enhanced global outcomes.

  6. Construction of quality-assured infant feeding process of care data repositories: Construction of the perinatal repository (Part 2).

    PubMed

    García-de-León-Chocano, Ricardo; Muñoz-Soler, Verónica; Sáez, Carlos; García-de-León-González, Ricardo; García-Gómez, Juan M

    2016-04-01

    This is the second in a series of two papers regarding the construction of data quality (DQ) assured repositories, based on population data from Electronic Health Records (EHR), for the reuse of information on infant feeding from birth until the age of two. This second paper describes the application of the computational process of constructing the first quality-assured repository for the reuse of information on infant feeding in the perinatal period, with the aim of studying relevant questions from the Baby Friendly Hospital Initiative (BFHI) and monitoring its deployment in our hospital. The construction of the repository was carried out using 13 semi-automated procedures to assess, recover or discard clinical data. The initial information consisted of perinatal forms from EHR related to 2048 births (Facts of Study, FoS) between 2009 and 2011, with a total of 433,308 observations of 223 variables. DQ was measured before and after the procedures using metrics related to eight quality dimensions: predictive value, correctness, duplication, consistency, completeness, contextualization, temporal-stability, and spatial-stability. Once the predictive variables were selected and DQ was assured, the final repository consisted of 1925 births, 107,529 observations and 73 quality-assured variables. The amount of discarded observations mainly corresponds to observations of non-predictive variables (52.90%) and the impact of the de-duplication process (20.58%) with respect to the total input data. Seven out of thirteen procedures achieved 100% of valid births, observations and variables. Moreover, 89% of births and ~98% of observations were consistent according to the experts׳ criteria. A multidisciplinary approach along with the quantification of DQ has allowed us to construct the first repository about infant feeding in the perinatal period based on EHR population data. Copyright © 2016 Elsevier Ltd. All rights reserved.

  7. A Fruit of Yucca Mountain: The Remote Waste Package Closure System

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kevin Skinner; Greg Housley; Colleen Shelton-Davis

    2011-11-01

    Was the death of the Yucca Mountain repository the fate of a technical lemon or a political lemon? Without caution, this debate could lure us away from capitalizing on the fruits of the project. In March 2009, Idaho National Laboratory (INL) successfully demonstrated the Waste Package Closure System, a full-scale prototype system for closing waste packages that were to be entombed in the now abandoned Yucca Mountain repository. This article describes the system, which INL designed and built, to weld the closure lids on the waste packages, nondestructively examine the welds using four different techniques, repair the welds if necessary,more » mitigate crack initiating stresses in the surfaces of the welds, evacuate and backfill the packages with an inert gas, and perform all of these tasks remotely. As a nation, we now have a proven method for securely sealing nuclear waste packages for long term storage—regardless of whether or not the future destination for these packages will be an underground repository. Additionally, many of the system’s features and concepts may benefit other remote nuclear applications.« less

  8. Report of the Peer Review Panel on the early site suitability evaluation of the Potential Repository Site at Yucca Mountain, Nevada; Yucca Mountain Site Characterization Project

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    1992-01-01

    The US Department of Energy (DOE) Yucca mountain Site Characterization Project Office (YMPO) assigned Science Applications International Corporation (SAIC), the Technical and Management Support Services (T&MSS) contractor to the YmPo, the task of conducting an Early Site Suitability Evaluation (ESSE) of the Yucca mountain site as a potential site for a high-level radioactive waste repository. First, the assignment called for the development of a method to evaluate a single site against the DOE General Guidelines for Recommendation of Sites for Nuclear Waste Repositories, 10 CFR Part 960. Then, using this method, an evaluation team, the ESSE Core Team, of seniormore » YMP scientists, engineers, and technical experts, evaluated new information obtained about the site since publication of the final Environmental Assessment (DOE, 1986) to determine if new suitability/unsuitability findings could be recommended. Finally, the Core Team identified further information and analyses needed to make final determinations for each of the guidelines. As part of the task, an independent peer review of the ESSE report has been conducted. Expertise was solicited that covered the entire spectrum of siting guidelines in 10 CFR Part 960 in order to provide a complete, in-depth critical review of the data evaluated and cited in the ESSE report, the methods used to evaluate the data, and the conclusions and recommendations offered by the report. Fourteen nationally recognized technical experts (Table 2) served on the Peer Review Panel. The comments from the Panel and the responses prepared by the ESSE Core Team, documented on formal Comment Response Forms, constitute the body of this document.« less

  9. Proliferation resistance assessment of various methods of spent nuclear fuel storage and disposal

    NASA Astrophysics Data System (ADS)

    Kollar, Lenka

    Many countries are planning to build or already are building new nuclear power plants to match their growing energy needs. Since all nuclear power plants handle nuclear materials that could potentially be converted and used for nuclear weapons, they each present a nuclear proliferation risk. Spent nuclear fuel presents the largest build-up of nuclear material at a power plant. This is a proliferation risk because spent fuel contains plutonium that can be chemically separated and used for a nuclear weapon. The International Atomic Energy Agency (IAEA) safeguards spent fuel in all non-nuclear weapons states that are party to the Non-Proliferation Treaty. Various safeguards methods are in use at nuclear power plants and research is underway to develop safeguards methods for spent fuel in centralized storage or underground storage and disposal. Each method of spent fuel storage presents different proliferation risks due to the nature of the storage method and the safeguards techniques that are utilized. Previous proliferation resistance and proliferation risk assessments have mainly compared nuclear material through the whole fuel cycle and not specifically focused on spent fuel storage. This project evaluates the proliferation resistance of the three main types of spent fuel storage: spent fuel pool, dry cask storage, and geological repository. The proliferation resistance assessment methodology that is used in this project is adopted from previous work and altered to be applicable to spent fuel storage. The assessment methodology utilizes various intrinsic and extrinsic proliferation-resistant attributes for each spent fuel storage type. These attributes are used to calculate a total proliferation resistant (PR) value. The maximum PR value is 1.00 and a greater number means that the facility is more proliferation resistant. Current data for spent fuel storage in the United States and around the world was collected. The PR values obtained from this data are 0.49 for the spent fuel pool, 0.42 for dry cask storage, 0.36 for the operating geological repository, and 0.28 for the closed geological repository. Therefore, the spent fuel pool is currently the most proliferation resistant method for storing spent fuel. The extrinsic attributes, mainly involving safeguards measures, affect the total PR value the most. As a result, several recommendations are made to improve the proliferation resistance of spent fuel. These recommendations include employing more advanced safeguards measures, such as verification techniques and remote monitoring, for dry cask storage and the geological repository. Dry cask storage facilities should also be located at the plant and in a secure building to minimize the proliferation risk. Finally, the cost-benefit analysis of increased safeguards needs to be considered. Taking these recommendations into account, the PR values of dry cask storage and the closed geological would be significantly increased, to 0.57 and 0.51, respectively. As a result, with increased safeguards to the safeguards level of the spent fuel pool, dry cask storage would be the most proliferation resistant method to store spent fuel. Therefore, the IAEA should continue to develop remote monitoring and cask storage verification techniques in order to improve the proliferation resistance of spent fuel.

  10. Object linking in repositories

    NASA Technical Reports Server (NTRS)

    Eichmann, David (Editor); Beck, Jon; Atkins, John; Bailey, Bill

    1992-01-01

    This topic is covered in three sections. The first section explores some of the architectural ramifications of extending the Eichmann/Atkins lattice-based classification scheme to encompass the assets of the full life cycle of software development. A model is considered that provides explicit links between objects in addition to the edges connecting classification vertices in the standard lattice. The second section gives a description of the efforts to implement the repository architecture using a commercially available object-oriented database management system. Some of the features of this implementation are described, and some of the next steps to be taken to produce a working prototype of the repository are pointed out. In the final section, it is argued that design and instantiation of reusable components have competing criteria (design-for-reuse strives for generality, design-with-reuse strives for specificity) and that providing mechanisms for each can be complementary rather than antagonistic. In particular, it is demonstrated how program slicing techniques can be applied to customization of reusable components.

  11. Developing the Tools for Geologic Repository Monitoring - Andra's Monitoring R and D Program - 12045

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Buschaert, S.; Lesoille, S.; Bertrand, J.

    2012-07-01

    The French Safety Guide recommends that Andra develop a monitoring program to be implemented during repository construction and conducted until (and possibly after) closure, in order to confirm expected behavior and enhance knowledge of relevant processes. To achieve this, Andra has developed an overall monitoring strategy and identified specific technical objectives to inform disposal process management on evolutions relevant to both the long term safety and reversible, pre-closure management of the repository. Andra has launched an ambitious R and D program to ensure that reliable, durable, metrologically qualified and tested monitoring systems will be available at the time of repositorymore » construction in order to respond to monitoring objectives. After four years of a specific R and D program, first observations are described and recommendations are proposed. The results derived from 4 years of Andra's R and D program allow three main observations to be shared. First, while other industries also invest in monitoring equipment, their obvious emphasis will always be on their specific requirements and needs, thus often only providing a partial match with repository requirements. Examples can be found for all available sensors, which are generally not resistant to radiation. Second, the very close scrutiny anticipated for the geologic disposal process is likely to place an unprecedented emphasis on the quality of monitoring results. It therefore seems important to emphasize specific developments with an aim at providing metrologically qualified systems. Third, adapting existing technology to specific repository needs, and providing adequate proof of their worth, is a lengthy process. In conclusion, it therefore seems prudent to plan ahead and to invest wisely in the adequate development of those monitoring tools that will likely be needed in the repository to respond to the implementers' and regulators' requirements, including those agreed and developed to respond to potential stakeholder expectations. (authors)« less

  12. In Search of a Better Search Engine

    ERIC Educational Resources Information Center

    Kolowich, Steve

    2009-01-01

    Early this decade, the number of Web-based documents stored on the servers of the University of Florida hovered near 300,000. By the end of 2006, that number had leapt to four million. Two years later, the university hosts close to eight million Web documents. Web sites for colleges and universities everywhere have become repositories for data…

  13. 75 FR 36427 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-25

    ... Cardiovascular Disease. Date: July 29, 2010. Time: 10 a.m. to 3 p.m. Agenda: To review and evaluate grant... Special Emphasis Panel, Resource Related Research Project in Lung Disease BioRepository. Date: July 15... Disorders Research; 93.837, Heart and Vascular Diseases Research; 93.838, Lung Diseases Research; 93.839...

  14. Natural analog studies: Licensing perspective

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bradbury, J.W.

    1995-09-01

    This report describes the licensing perspective of the term {open_quotes}natural analog studies{close_quotes} as used in CFR Part 60. It describes the misunderstandings related to its definition which has become evident during discussions at the U.S Nuclear Regulatory Commission meetings and tries to clarify the appropriate applications of natural analog studies to aspects of repository site characterization.

  15. 78 FR 43904 - Final Flood Hazard Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-22

    ...: Community map repository Community address Leon County, Texas, and Incorporated Areas Docket No.: FEMA-B... of Oakwood Town Hall, 135 East Broad Street, Oakwood, TX 75855. Unincorporated Areas of Leon County.... Leon County Judge's Office, 130 East St. Marys, Centerville, TX 75833. (Catalog of Federal Domestic...

  16. 32 CFR 156.6 - Common access card (CAC) investigation and adjudication.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... national background investigations may vary based on standing reciprocity treaties concerning identity... repository when available. (g) Reciprocity of CAC Determinations. (1) The sponsoring activity shall not re... determinations are not eligible to be transferred or reciprocally accepted. Reciprocity shall be based on final...

  17. SPECIATE 4.0: SPECIATION DATABASE DEVELOPMENT DOCUMENTATION--FINAL REPORT

    EPA Science Inventory

    SPECIATE is the U.S. EPA's repository of total organic compounds (TOC) and particulate matter (PM) speciation profiles of air pollution sources. This report documents how EPA developed the SPECIATE 4.0 database that replaces the prior version, SPECIATE 3.2. SPECIATE 4.0 includes ...

  18. High-level nuclear waste transport and storage assessment of potential impacts on tourism in the Las Vegas area. Nevada Nuclear Waste Storage Investigations Project

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    The literature review and empirical analyses presented in this report were undertaken, for the most part, between August and October 1983. They are not comprehensive. No primary data were gathered, nor were any formal surveys conducted. Additionally, because construction of a repository at Yucca Mountain, if that site is selected for a repository, is not scheduled to begin until 1993, engineering design and planned physical appearance of the repository are very preliminary. Therefore, specific design features or visual appearance were not addressed in the analyses. Finally, because actual transportation routes have not been designated, impacts on tourism generated specifically bymore » transportation activities are not considered separately. Chapter 2 briefly discusses possible means by which a repository could impact tourism in the Las Vegas area. Chapter 3 presents a review of previous research on alternative methods for predicting the response of people to potential hazards. A review of several published studies where these methods have been applied to facilities and activities associated with radioactive materials is included in Chapter 3. Chapter 4 contains five case studies of tourism impacts associated with past events that were perceived by the public to represent safety hazards. These perceptions of safety hazards were evidenced by news media coverage. These case studies were conducted specifically for this report. Conclusions of this preliminary analysis regarding the potential impact on tourism in the Las Vegas area of a repository at Yucca Mountain are in Chapter 5. Recommendations for further research are contained in Chapter 6.« less

  19. 10 CFR 960.3-2-2-5 - Formal site nomination.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Energy DEPARTMENT OF ENERGY GENERAL GUIDELINES FOR THE PRELIMINARY SCREENING OF POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY Implementation Guidelines § 960.3-2-2-5 Formal site nomination. After the final..., consideration of the available evidence, evaluations, and the resultant findings for the guidelines of subparts...

  20. 10 CFR 960.3-2-2-5 - Formal site nomination.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Energy DEPARTMENT OF ENERGY GENERAL GUIDELINES FOR THE PRELIMINARY SCREENING OF POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY Implementation Guidelines § 960.3-2-2-5 Formal site nomination. After the final..., consideration of the available evidence, evaluations, and the resultant findings for the guidelines of subparts...

  1. 10 CFR 960.3-2-2-5 - Formal site nomination.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Energy DEPARTMENT OF ENERGY GENERAL GUIDELINES FOR THE PRELIMINARY SCREENING OF POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY Implementation Guidelines § 960.3-2-2-5 Formal site nomination. After the final..., consideration of the available evidence, evaluations, and the resultant findings for the guidelines of subparts...

  2. 10 CFR 960.3-2-2-5 - Formal site nomination.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Energy DEPARTMENT OF ENERGY GENERAL GUIDELINES FOR THE PRELIMINARY SCREENING OF POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY Implementation Guidelines § 960.3-2-2-5 Formal site nomination. After the final..., consideration of the available evidence, evaluations, and the resultant findings for the guidelines of subparts...

  3. Software Hardware Asset Reuse Enterprise (SHARE) Repository Framework Final Report: Component Specification and Ontology

    DTIC Science & Technology

    2009-08-19

    SSDS Ship Self Defense System TSTS Total Ship Training System UDDI Universal Description, Discovery, and Integration UML Unified Modeling...34ContractorOrganization" type="ContractorOrganizationType"> <xs:annotation> <xs:documentation>Identifies a contractor organization resposible for the

  4. 10 CFR 2.1023 - Immediate effectiveness.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Waste at a Geologic Repository § 2.1023 Immediate effectiveness. (a) Pending review and final decision by the Commission, and initial decision resolving all issues before the presiding officer in favor of... issued in accordance with § 2.342 that stays the effectiveness of an initial decision; or (2) As...

  5. Yucca Mountain nuclear waste repository prompts heated congressional hearing

    NASA Astrophysics Data System (ADS)

    Showstack, Randy

    2011-11-01

    Although the final report of the Blue Ribbon Commission on America's Nuclear Future is not expected until January 2012, the tentative conclusions of the commission's draft report were dissected during a recent joint hearing by two subcommittees of the House of Representatives' Committee on Science, Space, and Technology. Among the more heated issues debated at the hearing was the fate of the stalled Yucca Mountain nuclear waste repository in Nevada. The Blue Ribbon Commission's (BRC) draft report includes recommendations for managing nuclear waste and for developing one or more permanent deep geological repositories and interim storage facilities, but the report does not address the future of Yucca Mountain. The BRC charter indicates that the commission is to "conduct a comprehensive review of policies for managing the back end of the nuclear fuel cycle." However, the draft report states that the commission was not asked to consider, and therefore did not address, several key issues. "We have not rendered an opinion on the suitability of the Yucca Mountain site or on the request to withdraw the license application for Yucca Mountain," the draft report states.

  6. Bayesian approach to transforming public gene expression repositories into disease diagnosis databases.

    PubMed

    Huang, Haiyan; Liu, Chun-Chi; Zhou, Xianghong Jasmine

    2010-04-13

    The rapid accumulation of gene expression data has offered unprecedented opportunities to study human diseases. The National Center for Biotechnology Information Gene Expression Omnibus is currently the largest database that systematically documents the genome-wide molecular basis of diseases. However, thus far, this resource has been far from fully utilized. This paper describes the first study to transform public gene expression repositories into an automated disease diagnosis database. Particularly, we have developed a systematic framework, including a two-stage Bayesian learning approach, to achieve the diagnosis of one or multiple diseases for a query expression profile along a hierarchical disease taxonomy. Our approach, including standardizing cross-platform gene expression data and heterogeneous disease annotations, allows analyzing both sources of information in a unified probabilistic system. A high level of overall diagnostic accuracy was shown by cross validation. It was also demonstrated that the power of our method can increase significantly with the continued growth of public gene expression repositories. Finally, we showed how our disease diagnosis system can be used to characterize complex phenotypes and to construct a disease-drug connectivity map.

  7. Software Hardware Asset Reuse Enterprise (SHARE) Repository Framework Final Report: Component Specification and Ontology

    DTIC Science & Technology

    2008-09-30

    89 Integrated Surface Ship ASW Combat System (AN/SQQ-89) SSDS Ship Self Defense System TSTS Total Ship Training System UDDI Universal Description...34ContractorOrganization" type="ContractorOrganizationType"> <xs:annotation> <xs:documentation>Identifies a contractor organization resposible for the

  8. Supporting Quality Timely PhD Completions: Delivering Research Outcomes

    ERIC Educational Resources Information Center

    Gasson, Susan

    2015-01-01

    The case study used a three-phase organising process to explain how design and implementation of an accessible and interactive electronic thesis submission form streamlined quality assurance of theses and their timely dissemination via an online thesis repository. The quality of the theses submitted is assured by key academics in their final sign…

  9. Unified Database Development Program. Final Report.

    ERIC Educational Resources Information Center

    Thomas, Everett L., Jr.; Deem, Robert N.

    The objective of the unified database (UDB) program was to develop an automated information system that would be useful in the design, development, testing, and support of new Air Force aircraft weapon systems. Primary emphasis was on the development of: (1) a historical logistics data repository system to provide convenient and timely access to…

  10. Food entries in a large allergy data repository

    PubMed Central

    Plasek, Joseph M.; Goss, Foster R.; Lai, Kenneth H.; Lau, Jason J.; Seger,, Diane L.; Blumenthal, Kimberly G.; Wickner, Paige G.; Slight, Sarah P.; Chang, Frank Y.; Topaz, Maxim; Bates, David W.

    2016-01-01

    Objective Accurate food adverse sensitivity documentation in electronic health records (EHRs) is crucial to patient safety. This study examined, encoded, and grouped foods that caused any adverse sensitivity in a large allergy repository using natural language processing and standard terminologies. Methods Using the Medical Text Extraction, Reasoning, and Mapping System (MTERMS), we processed both structured and free-text entries stored in an enterprise-wide allergy repository (Partners’ Enterprise-wide Allergy Repository), normalized diverse food allergen terms into concepts, and encoded these concepts using the Systematized Nomenclature of Medicine – Clinical Terms (SNOMED-CT) and Unique Ingredient Identifiers (UNII) terminologies. Concept coverage also was assessed for these two terminologies. We further categorized allergen concepts into groups and calculated the frequencies of these concepts by group. Finally, we conducted an external validation of MTERMS’s performance when identifying food allergen terms, using a randomized sample from a different institution. Results We identified 158 552 food allergen records (2140 unique terms) in the Partners repository, corresponding to 672 food allergen concepts. High-frequency groups included shellfish (19.3%), fruits or vegetables (18.4%), dairy (9.0%), peanuts (8.5%), tree nuts (8.5%), eggs (6.0%), grains (5.1%), and additives (4.7%). Ambiguous, generic concepts such as “nuts” and “seafood” accounted for 8.8% of the records. SNOMED-CT covered more concepts than UNII in terms of exact (81.7% vs 68.0%) and partial (14.3% vs 9.7%) matches. Discussion Adverse sensitivities to food are diverse, and existing standard terminologies have gaps in their coverage of the breadth of allergy concepts. Conclusion New strategies are needed to represent and standardize food adverse sensitivity concepts, to improve documentation in EHRs. PMID:26384406

  11. Food entries in a large allergy data repository.

    PubMed

    Plasek, Joseph M; Goss, Foster R; Lai, Kenneth H; Lau, Jason J; Seger, Diane L; Blumenthal, Kimberly G; Wickner, Paige G; Slight, Sarah P; Chang, Frank Y; Topaz, Maxim; Bates, David W; Zhou, Li

    2016-04-01

    Accurate food adverse sensitivity documentation in electronic health records (EHRs) is crucial to patient safety. This study examined, encoded, and grouped foods that caused any adverse sensitivity in a large allergy repository using natural language processing and standard terminologies. Using the Medical Text Extraction, Reasoning, and Mapping System (MTERMS), we processed both structured and free-text entries stored in an enterprise-wide allergy repository (Partners' Enterprise-wide Allergy Repository), normalized diverse food allergen terms into concepts, and encoded these concepts using the Systematized Nomenclature of Medicine - Clinical Terms (SNOMED-CT) and Unique Ingredient Identifiers (UNII) terminologies. Concept coverage also was assessed for these two terminologies. We further categorized allergen concepts into groups and calculated the frequencies of these concepts by group. Finally, we conducted an external validation of MTERMS's performance when identifying food allergen terms, using a randomized sample from a different institution. We identified 158 552 food allergen records (2140 unique terms) in the Partners repository, corresponding to 672 food allergen concepts. High-frequency groups included shellfish (19.3%), fruits or vegetables (18.4%), dairy (9.0%), peanuts (8.5%), tree nuts (8.5%), eggs (6.0%), grains (5.1%), and additives (4.7%). Ambiguous, generic concepts such as "nuts" and "seafood" accounted for 8.8% of the records. SNOMED-CT covered more concepts than UNII in terms of exact (81.7% vs 68.0%) and partial (14.3% vs 9.7%) matches. Adverse sensitivities to food are diverse, and existing standard terminologies have gaps in their coverage of the breadth of allergy concepts. New strategies are needed to represent and standardize food adverse sensitivity concepts, to improve documentation in EHRs. © The Author 2015. Published by Oxford University Press on behalf of the American Medical Informatics Association. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  12. OWLing Clinical Data Repositories With the Ontology Web Language

    PubMed Central

    Pastor, Xavier; Lozano, Esther

    2014-01-01

    Background The health sciences are based upon information. Clinical information is usually stored and managed by physicians with precarious tools, such as spreadsheets. The biomedical domain is more complex than other domains that have adopted information and communication technologies as pervasive business tools. Moreover, medicine continuously changes its corpus of knowledge because of new discoveries and the rearrangements in the relationships among concepts. This scenario makes it especially difficult to offer good tools to answer the professional needs of researchers and constitutes a barrier that needs innovation to discover useful solutions. Objective The objective was to design and implement a framework for the development of clinical data repositories, capable of facing the continuous change in the biomedicine domain and minimizing the technical knowledge required from final users. Methods We combined knowledge management tools and methodologies with relational technology. We present an ontology-based approach that is flexible and efficient for dealing with complexity and change, integrated with a solid relational storage and a Web graphical user interface. Results Onto Clinical Research Forms (OntoCRF) is a framework for the definition, modeling, and instantiation of data repositories. It does not need any database design or programming. All required information to define a new project is explicitly stated in ontologies. Moreover, the user interface is built automatically on the fly as Web pages, whereas data are stored in a generic repository. This allows for immediate deployment and population of the database as well as instant online availability of any modification. Conclusions OntoCRF is a complete framework to build data repositories with a solid relational storage. Driven by ontologies, OntoCRF is more flexible and efficient to deal with complexity and change than traditional systems and does not require very skilled technical people facilitating the engineering of clinical software systems. PMID:25599697

  13. OWLing Clinical Data Repositories With the Ontology Web Language.

    PubMed

    Lozano-Rubí, Raimundo; Pastor, Xavier; Lozano, Esther

    2014-08-01

    The health sciences are based upon information. Clinical information is usually stored and managed by physicians with precarious tools, such as spreadsheets. The biomedical domain is more complex than other domains that have adopted information and communication technologies as pervasive business tools. Moreover, medicine continuously changes its corpus of knowledge because of new discoveries and the rearrangements in the relationships among concepts. This scenario makes it especially difficult to offer good tools to answer the professional needs of researchers and constitutes a barrier that needs innovation to discover useful solutions. The objective was to design and implement a framework for the development of clinical data repositories, capable of facing the continuous change in the biomedicine domain and minimizing the technical knowledge required from final users. We combined knowledge management tools and methodologies with relational technology. We present an ontology-based approach that is flexible and efficient for dealing with complexity and change, integrated with a solid relational storage and a Web graphical user interface. Onto Clinical Research Forms (OntoCRF) is a framework for the definition, modeling, and instantiation of data repositories. It does not need any database design or programming. All required information to define a new project is explicitly stated in ontologies. Moreover, the user interface is built automatically on the fly as Web pages, whereas data are stored in a generic repository. This allows for immediate deployment and population of the database as well as instant online availability of any modification. OntoCRF is a complete framework to build data repositories with a solid relational storage. Driven by ontologies, OntoCRF is more flexible and efficient to deal with complexity and change than traditional systems and does not require very skilled technical people facilitating the engineering of clinical software systems.

  14. Enriching text with images and colored light

    NASA Astrophysics Data System (ADS)

    Sekulovski, Dragan; Geleijnse, Gijs; Kater, Bram; Korst, Jan; Pauws, Steffen; Clout, Ramon

    2008-01-01

    We present an unsupervised method to enrich textual applications with relevant images and colors. The images are collected by querying large image repositories and subsequently the colors are computed using image processing. A prototype system based on this method is presented where the method is applied to song lyrics. In combination with a lyrics synchronization algorithm the system produces a rich multimedia experience. In order to identify terms within the text that may be associated with images and colors, we select noun phrases using a part of speech tagger. Large image repositories are queried with these terms. Per term representative colors are extracted using the collected images. Hereto, we either use a histogram-based or a mean shift-based algorithm. The representative color extraction uses the non-uniform distribution of the colors found in the large repositories. The images that are ranked best by the search engine are displayed on a screen, while the extracted representative colors are rendered on controllable lighting devices in the living room. We evaluate our method by comparing the computed colors to standard color representations of a set of English color terms. A second evaluation focuses on the distance in color between a queried term in English and its translation in a foreign language. Based on results from three sets of terms, a measure of suitability of a term for color extraction based on KL Divergence is proposed. Finally, we compare the performance of the algorithm using either the automatically indexed repository of Google Images and the manually annotated Flickr.com. Based on the results of these experiments, we conclude that using the presented method we can compute the relevant color for a term using a large image repository and image processing.

  15. COINSTAC: A Privacy Enabled Model and Prototype for Leveraging and Processing Decentralized Brain Imaging Data.

    PubMed

    Plis, Sergey M; Sarwate, Anand D; Wood, Dylan; Dieringer, Christopher; Landis, Drew; Reed, Cory; Panta, Sandeep R; Turner, Jessica A; Shoemaker, Jody M; Carter, Kim W; Thompson, Paul; Hutchison, Kent; Calhoun, Vince D

    2016-01-01

    The field of neuroimaging has embraced the need for sharing and collaboration. Data sharing mandates from public funding agencies and major journal publishers have spurred the development of data repositories and neuroinformatics consortia. However, efficient and effective data sharing still faces several hurdles. For example, open data sharing is on the rise but is not suitable for sensitive data that are not easily shared, such as genetics. Current approaches can be cumbersome (such as negotiating multiple data sharing agreements). There are also significant data transfer, organization and computational challenges. Centralized repositories only partially address the issues. We propose a dynamic, decentralized platform for large scale analyses called the Collaborative Informatics and Neuroimaging Suite Toolkit for Anonymous Computation (COINSTAC). The COINSTAC solution can include data missing from central repositories, allows pooling of both open and "closed" repositories by developing privacy-preserving versions of widely-used algorithms, and incorporates the tools within an easy-to-use platform enabling distributed computation. We present an initial prototype system which we demonstrate on two multi-site data sets, without aggregating the data. In addition, by iterating across sites, the COINSTAC model enables meta-analytic solutions to converge to "pooled-data" solutions (i.e., as if the entire data were in hand). More advanced approaches such as feature generation, matrix factorization models, and preprocessing can be incorporated into such a model. In sum, COINSTAC enables access to the many currently unavailable data sets, a user friendly privacy enabled interface for decentralized analysis, and a powerful solution that complements existing data sharing solutions.

  16. Co-production of Health enabled by next generation personal health systems.

    PubMed

    Boye, Niels

    2012-01-01

    This paper describes the theoretical principles for the establishment of a parallel and complementary modality of healthcare delivery - named Coproduction of Health (CpH). This service-model activates digital data, information, and knowledge about health, healthy choices, and the individuals' health-state and computes through personalized models context-aware communication and advice. "Lightweight technologies" (smartphones, tablets, application stores) would serve as the technology close to the end-users (citizens, patients, clients, customers), connecting them with "big data" in conventionally and non-conventionally organized data repositories. The CpH modality aims at providing synergies between professional healthcare, selfcare, informal care and provides data-fusion from several sources such as health characteristics of consumer goods, from sensors, actuators, and health related data-repositories, and turns this into "health added value" for the individual. A theoretical business model respecting healthcare values, ethics, and legal foundation is also sketched out.

  17. The Geothermal Data Repository: Five Years of Open Geothermal Data, Benefits to the Community: Preprint

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Weers, Jonathan D; Taverna, Nicole; Anderson, Arlene

    In the five years since its inception, the Department of Energy's (DOE) Geothermal Data Repository (GDR) has grown from the simple idea of storing public data in a centralized location to a valuable tool at the center of the DOE open data movement where it is providing a tangible benefit to the geothermal scientific community. Throughout this time, the GDR project team has been working closely with the community to refine the data submission process, improve the quality of submitted data, and embrace modern proper data management strategies to maximize the value and utility of submitted data. This paper exploresmore » some of the motivations behind various improvements to the GDR over the last 5 years, changes in data submission trends, and the ways in which these improvements have helped to drive research, fuel innovation, and accelerate the adoption of geothermal technologies.« less

  18. Reconstructing a hydrogen-driven microbial metabolic network in Opalinus Clay rock.

    PubMed

    Bagnoud, Alexandre; Chourey, Karuna; Hettich, Robert L; de Bruijn, Ino; Andersson, Anders F; Leupin, Olivier X; Schwyn, Bernhard; Bernier-Latmani, Rizlan

    2016-10-14

    The Opalinus Clay formation will host geological nuclear waste repositories in Switzerland. It is expected that gas pressure will build-up due to hydrogen production from steel corrosion, jeopardizing the integrity of the engineered barriers. In an in situ experiment located in the Mont Terri Underground Rock Laboratory, we demonstrate that hydrogen is consumed by microorganisms, fuelling a microbial community. Metagenomic binning and metaproteomic analysis of this deep subsurface community reveals a carbon cycle driven by autotrophic hydrogen oxidizers belonging to novel genera. Necromass is then processed by fermenters, followed by complete oxidation to carbon dioxide by heterotrophic sulfate-reducing bacteria, which closes the cycle. This microbial metabolic web can be integrated in the design of geological repositories to reduce pressure build-up. This study shows that Opalinus Clay harbours the potential for chemolithoautotrophic-based system, and provides a model of microbial carbon cycle in deep subsurface environments where hydrogen and sulfate are present.

  19. The Geothermal Data Repository: Five Years of Open Geothermal Data, Benefits to the Community

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Weers, Jonathan D; Taverna, Nicole; Anderson, Arlene

    In the five years since its inception, the Department of Energy's (DOE) Geothermal Data Repository (GDR) has grown from the simple idea of storing public data in a centralized location to a valuable tool at the center of the DOE open data movement where it is providing a tangible benefit to the geothermal scientific community. Throughout this time, the GDR project team has been working closely with the community to refine the data submission process, improve the quality of submitted data, and embrace modern proper data management strategies to maximize the value and utility of submitted data. This paper exploresmore » some of the motivations behind various improvements to the GDR over the last 5 years, changes in data submission trends, and the ways in which these improvements have helped to drive research, fuel innovation, and accelerate the adoption of geothermal technologies.« less

  20. Reconstructing a hydrogen-driven microbial metabolic network in Opalinus Clay rock

    PubMed Central

    Bagnoud, Alexandre; Chourey, Karuna; Hettich, Robert L.; de Bruijn, Ino; Andersson, Anders F.; Leupin, Olivier X.; Schwyn, Bernhard; Bernier-Latmani, Rizlan

    2016-01-01

    The Opalinus Clay formation will host geological nuclear waste repositories in Switzerland. It is expected that gas pressure will build-up due to hydrogen production from steel corrosion, jeopardizing the integrity of the engineered barriers. In an in situ experiment located in the Mont Terri Underground Rock Laboratory, we demonstrate that hydrogen is consumed by microorganisms, fuelling a microbial community. Metagenomic binning and metaproteomic analysis of this deep subsurface community reveals a carbon cycle driven by autotrophic hydrogen oxidizers belonging to novel genera. Necromass is then processed by fermenters, followed by complete oxidation to carbon dioxide by heterotrophic sulfate-reducing bacteria, which closes the cycle. This microbial metabolic web can be integrated in the design of geological repositories to reduce pressure build-up. This study shows that Opalinus Clay harbours the potential for chemolithoautotrophic-based system, and provides a model of microbial carbon cycle in deep subsurface environments where hydrogen and sulfate are present. PMID:27739431

  1. Control of stacking loads in final waste disposal according to the borehole technique

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Feuser, W.; Barnert, E.; Vijgen, H.

    1996-12-01

    The semihydrostatic model has been developed in order to assess the mechanical toads acting on heat-generating ILW(Q) and HTGR fuel element waste packages to be emplaced in vertical boreholes according to the borehole technique in underground rock salt formations. For the experimental validation of the theory, laboratory test stands reduced in scale are set up to simulate the bottom section of a repository borehole. A comparison of the measurement results with the data computed by the model, a correlation between the test stand results, and a systematic determination of material-typical crushed salt parameters in a separate research project will servemore » to derive a set of characteristic equations enabling a description of real conditions in a future repository.« less

  2. Do Open Access Electronic Theses and Dissertations Diminish Publishing Opportunities in the Sciences?

    ERIC Educational Resources Information Center

    Ramírez, Marisa L.; McMillan, Gail; Dalton, Joan T.; Hanlon, Ann; Smith, Heather S.; Kern, Chelsea

    2014-01-01

    In academia, there is a growing acceptance of sharing the final electronic version of graduate work, such as a thesis or dissertation, in an online university repository. Though previous studies have shown that journal editors are willing to consider manuscripts derived from electronic theses and dissertations (ETDs), faculty advisors and graduate…

  3. Criteria for the evaluation and certification of long-term digital archives in the earth sciences

    NASA Astrophysics Data System (ADS)

    Klump, Jens

    2010-05-01

    Digital information has become an indispensable part of our cultural and scientific heritage. Scientific findings, historical documents and cultural achievements are to a rapidly increasing extent being presented in electronic form - in many cases exclusively so. However, besides the invaluable advantages offered by this form, it also carries a serious disadvantage: users need to invest a great deal of technical effort in accessing the information. Also, the underlying technology is still undergoing further development at an exceptionally fast pace. The rapid obsolescence of the technology required to read the information combined with the frequently imperceptible physical decay of the media themselves represents a serious threat to preservation of the information content. Many data sets in earth science research are from observations that cannot be repeated. This makes these digital assets particularly valuable. Therefore, these data should be kept and made available for re-use long after the end of the project from which they originated. Since research projects only run for a relatively short period of time, it is advisable to shift the burden of responsibility for long-term data curation from the individual researcher to a trusted data repository or archive. But what makes a trusted data repository? Each trusted digital repository has its own targets and specifications. The trustworthiness of digital repositories can be tested and assessed on the basis of a criteria catalogue. This is the main focus of the work of the nestor working group "Trusted repositories - Certification". It identifies criteria which permit the trustworthiness of a digital repository to be evaluated, both at the organisational and technical levels. The criteria are defined in close collaboration with a wide range of different memory organisations, producers of information, experts and other interested parties. This open approach ensures a high degree of universal validity, suitability for daily practical use and also broad-based acceptance of the results. The criteria catalogue is also intended to present the option of documenting trustworthiness by means of certification in a standardised national or international process. The criteria catalogue is based on the Reference Model for an Open Archival Information System (OAIS, ISO 14721:2003) With its broad approach, the nestor criteria catalogue for trusted digital repositories has to remain on a high level of abstraction. For application in the earth sciences the evaluation criteria need to be transferred into the context of earth science data and their designated user community. This presentation offers a brief introduction to the problems surrounding the long-term preservation of digital objects. This introduction is followed by a proposed application of the criteria catalogue for trusted digital repositories to the context of earth science data and their long-term preservation.

  4. Current Status of The Romanian National Deep Geological Repository Program

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Radu, M.; Nicolae, R.; Nicolae, D.

    2008-07-01

    Construction of a deep geological repository is a very demanding and costly task. By now, countries that have Candu reactors, have not processed the spent fuel passing to the interim storage as a preliminary step of final disposal within the nuclear fuel cycle back-end. Romania, in comparison to other nations, represents a rather small territory, with high population density, wherein the geological formation areas with radioactive waste storage potential are limited and restricted not only from the point of view of the selection criteria due to the rocks natural characteristics, but also from the point of view of their involvementmore » in social and economical activities. In the framework of the national R and D Programs, series of 'Map investigations' have been made regarding the selection and preliminary characterization of the host geological formation for the nation's spent fuel deep geological repository. The fact that Romania has many deposits of natural gas, oil, ore and geothermal water, and intensively utilizes soil and also is very forested, cause some of the apparent acceptable sites to be rejected in the subsequent analysis. Currently, according to the Law on the spent fuel and radioactive waste management, including disposal, The National Agency of Radioactive Waste is responsible and coordinates the national strategy in the field and, subsequently, further actions will be decided. The Romanian National Strategy, approved in 2004, projects the operation of a deep geological repository to begin in 2055. (authors)« less

  5. An algorithm to detect and communicate the differences in computational models describing biological systems.

    PubMed

    Scharm, Martin; Wolkenhauer, Olaf; Waltemath, Dagmar

    2016-02-15

    Repositories support the reuse of models and ensure transparency about results in publications linked to those models. With thousands of models available in repositories, such as the BioModels database or the Physiome Model Repository, a framework to track the differences between models and their versions is essential to compare and combine models. Difference detection not only allows users to study the history of models but also helps in the detection of errors and inconsistencies. Existing repositories lack algorithms to track a model's development over time. Focusing on SBML and CellML, we present an algorithm to accurately detect and describe differences between coexisting versions of a model with respect to (i) the models' encoding, (ii) the structure of biological networks and (iii) mathematical expressions. This algorithm is implemented in a comprehensive and open source library called BiVeS. BiVeS helps to identify and characterize changes in computational models and thereby contributes to the documentation of a model's history. Our work facilitates the reuse and extension of existing models and supports collaborative modelling. Finally, it contributes to better reproducibility of modelling results and to the challenge of model provenance. The workflow described in this article is implemented in BiVeS. BiVeS is freely available as source code and binary from sems.uni-rostock.de. The web interface BudHat demonstrates the capabilities of BiVeS at budhat.sems.uni-rostock.de. © The Author 2015. Published by Oxford University Press.

  6. Region-to-area screening methodology for the Crystalline Repository Project

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None

    1985-04-01

    The purpose of this document is to describe the Crystalline Repository Project's (CRP) process for region-to-area screening of exposed and near-surface crystalline rock bodies in the three regions of the conterminous United States where crystalline rock is being evaluated as a potential host for the second nuclear waste repository (i.e., in the North Central, Northeastern, and Southeastern Regions). This document indicates how the US Department of Energy's (DOE) General Guidelines for the Recommendation of Sites for Nuclear Waste Repositories (10 CFR 960) were used to select and apply factors and variables for the region-to-area screening, explains how these factors andmore » variable are to be applied in the region-to-area screening, and indicates how this methodology relates to the decision process leading to the selection of candidate areas. A brief general discussion of the screening process from the national survey through area screening and site recommendation is presented. This discussion sets the scene for detailed discussions which follow concerning the region-to-area screening process, the guidance provided by the DOE Siting Guidelines for establishing disqualifying factors and variables for screening, and application of the disqualifying factors and variables in the screening process. This document is complementary to the regional geologic and environmental characterization reports to be issued in the summer of 1985 as final documents. These reports will contain the geologic and environmental data base that will be used in conjunction with the methodology to conduct region-to-area screening.« less

  7. Site characterization report for the basalt waste isolation project. Volume II

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None

    1982-11-01

    The reference location for a repository in basalt for the terminal storage of nuclear wastes on the Hanford Site and the candidate horizons within this reference repository location have been identified and the preliminary characterization work in support of the site screening process has been completed. Fifteen technical questions regarding the qualification of the site were identified to be addressed during the detailed site characterization phase of the US Department of Energy-National Waste Terminal Storage Program site selection process. Resolution of these questions will be provided in the final site characterization progress report, currently planned to be issued in 1987,more » and in the safety analysis report to be submitted with the License Application. The additional information needed to resolve these questions and the plans for obtaining the information have been identified. This Site Characterization Report documents the results of the site screening process, the preliminary site characterization data, the technical issues that need to be addressed, and the plans for resolving these issues. Volume 2 contains chapters 6 through 12: geochemistry; surface hydrology; climatology, meteorology, and air quality; environmental, land-use, and socioeconomic characteristics; repository design; waste package; and performance assessment.« less

  8. Generating and manipulating quantized vortices on-demand in a Bose-Einstein condensate: A numerical study

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gertjerenken, B.; Kevrekidis, P. G.; Carretero-González, R.

    Here, we numerically investigate an experimentally viable method for generating and manipulating on-demand several vortices in a highly oblate atomic Bose-Einstein condensate (BEC) in order to initialize complex vortex distributions for studies of vortex dynamics. The method utilizes moving laser beams to generate, capture, and transport vortices inside and outside the BEC. This methodology is examined in detail and shows a wide parameter range of applicability for the prototypical two-vortex case, as well as case examples of producing and manipulating several vortices for which there is no net circulation, corresponding to equal numbers of positive and negative circulation vortices, andmore » cases for which there is one net quantum of circulation. We also find that the presence of dissipation can help stabilize the pinning of the vortices on their respective laser beam pinning sites. Finally, we illustrate how to utilize laser beams as repositories that hold large numbers of vortices and how to deposit individual vortices in a sequential fashion in the repositories in order to construct superfluid flows about the repository beams with several quanta of circulation.« less

  9. Generating and manipulating quantized vortices on-demand in a Bose-Einstein condensate: A numerical study

    DOE PAGES

    Gertjerenken, B.; Kevrekidis, P. G.; Carretero-González, R.; ...

    2016-02-01

    Here, we numerically investigate an experimentally viable method for generating and manipulating on-demand several vortices in a highly oblate atomic Bose-Einstein condensate (BEC) in order to initialize complex vortex distributions for studies of vortex dynamics. The method utilizes moving laser beams to generate, capture, and transport vortices inside and outside the BEC. This methodology is examined in detail and shows a wide parameter range of applicability for the prototypical two-vortex case, as well as case examples of producing and manipulating several vortices for which there is no net circulation, corresponding to equal numbers of positive and negative circulation vortices, andmore » cases for which there is one net quantum of circulation. We also find that the presence of dissipation can help stabilize the pinning of the vortices on their respective laser beam pinning sites. Finally, we illustrate how to utilize laser beams as repositories that hold large numbers of vortices and how to deposit individual vortices in a sequential fashion in the repositories in order to construct superfluid flows about the repository beams with several quanta of circulation.« less

  10. Development of a Korean reference HLW disposal system under the Korean representative geologic conditions

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Choi, Heui-Joo; Lee, Jong Youl; Choi, Jongwon

    2007-07-01

    The development of a Korean Reference disposal System for the spent fuels from PWR and CANDU reactors is outlined in this paper. Around 36,000 tU of spent fuels are being projected based on the lifetimes of 28 nuclear power reactors in Korea. Since the site for the geological disposal has not yet been decided, a hypothetical site with representative Korean geologic conditions is proposed for the conceptual design of the repository. The disposal rates of the spent fuels are determined according to the total operation time of 55 years. The canisters are optimized by considering natural Korean conditions, and themore » buffer is designed with domestic Ca-bentonite. The depth of the repository is determined to be 500 m below the ground's surface. The canister separation distances are determined through a thermal analysis. The main features of the repository are presented from the layout to the closure. A computer program has been developed to calculate and analyze the volume and the area of the disposal system to help in the cost analysis. The final output of the design is presented as a unit disposal cost, US $315 /kgU. (authors)« less

  11. 75 FR 75207 - Regulation SBSR-Reporting and Dissemination of Security-Based Swap Information

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-02

    ...In accordance with Section 763 (``Section 763'') and Section 766 (``Section 766'') of Title VII (``Title VII'') of the Dodd-Frank Wall Street Reform and Consumer Protection Act (the ``Dodd-Frank Act''), the Securities and Exchange Commission (``SEC'' or ``Commission'') is proposing Regulation SBSR--Reporting and Dissemination of Security-Based Swap Information (``Regulation SBSR'') under the Securities Exchange Act of 1934 (``Exchange Act'').\\1\\ Proposed Regulation SBSR would provide for the reporting of security- based swap information to registered security-based swap data repositories or the Commission and the public dissemination of security-based swap transaction, volume, and pricing information. Registered security-based swap data repositories would be required to establish and maintain certain policies and procedures regarding how transaction data are reported and disseminated, and participants of registered security-based swap data repositories that are security- based swap dealers or major security-based swap participants would be required to establish and maintain policies and procedures that are reasonably designed to ensure that they comply with applicable reporting obligations. Finally, proposed Regulation SBSR also would require a registered SDR to register with the Commission as a securities information processor on existing Form SIP. ---------------------------------------------------------------------------

  12. Container Approval for the Disposal of Radioactive Waste with Negligible Heat Generation in the German Konrad Repository - 12148

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Voelzke, Holger; Nieslony, Gregor; Ellouz, Manel

    Since the license for the Konrad repository was finally confirmed by legal decision in 2007, the Federal Institute for Radiation Protection (BfS) has been performing further planning and preparation work to prepare the repository for operation. Waste conditioning and packaging has been continued by different waste producers as the nuclear industry and federal research institutes on the basis of the official disposal requirements. The necessary prerequisites for this are approved containers as well as certified waste conditioning and packaging procedures. The Federal Institute for Materials Research and Testing (BAM) is responsible for container design testing and evaluation of quality assurancemore » measures on behalf of BfS under consideration of the Konrad disposal requirements. Besides assessing the container handling stability (stacking tests, handling loads), design testing procedures are performed that include fire tests (800 deg. C, 1 hour) and drop tests from different heights and drop orientations. This paper presents the current state of BAM design testing experiences about relevant container types (box shaped, cylindrical) made of steel sheets, ductile cast iron or concrete. It explains usual testing and evaluation methods which range from experimental testing to analytical and numerical calculations. Another focus has been laid on already existing containers and packages. The question arises as to how they can be evaluated properly especially with respect to lack of completeness of safety assessment and fabrication documentation. At present BAM works on numerous applications for container design testing for the Konrad repository. Some licensing procedures were successfully finished in the past and BfS certified several container types like steel sheet, concrete until cast iron containers which are now available for waste packaging for final disposal. However, large quantities of radioactive wastes had been placed into interim storage using containers which are not already licensed for the Konrad repository. Safety assessment of these so-called 'old' containers is a big challenge for all parties because documentation sheets about container design testing and fabrication often contain gaps or have not yet been completed. Appropriate solution strategies are currently under development and discussion. Furthermore, BAM has successfully initiated and established an information forum, called 'ERFA QM Konrad Containers', which facilitates discussions on various issues of common interest with respect to Konrad container licensing procedures as well as the interpretation of disposal requirements under consideration of operational needs. Thus, it provides additional, valuable supports for container licensing procedures. (authors)« less

  13. The Belgian repository of fundamental atomic data and stellar spectra (BRASS). I. Cross-matching atomic databases of astrophysical interest

    NASA Astrophysics Data System (ADS)

    Laverick, M.; Lobel, A.; Merle, T.; Royer, P.; Martayan, C.; David, M.; Hensberge, H.; Thienpont, E.

    2018-04-01

    Context. Fundamental atomic parameters, such as oscillator strengths, play a key role in modelling and understanding the chemical composition of stars in the Universe. Despite the significant work underway to produce these parameters for many astrophysically important ions, uncertainties in these parameters remain large and can propagate throughout the entire field of astronomy. Aims: The Belgian repository of fundamental atomic data and stellar spectra (BRASS) aims to provide the largest systematic and homogeneous quality assessment of atomic data to date in terms of wavelength, atomic and stellar parameter coverage. To prepare for it, we first compiled multiple literature occurrences of many individual atomic transitions, from several atomic databases of astrophysical interest, and assessed their agreement. In a second step synthetic spectra will be compared against extremely high-quality observed spectra, for a large number of BAFGK spectral type stars, in order to critically evaluate the atomic data of a large number of important stellar lines. Methods: Several atomic repositories were searched and their data retrieved and formatted in a consistent manner. Data entries from all repositories were cross-matched against our initial BRASS atomic line list to find multiple occurrences of the same transition. Where possible we used a new non-parametric cross-match depending only on electronic configurations and total angular momentum values. We also checked for duplicate entries of the same physical transition, within each retrieved repository, using the non-parametric cross-match. Results: We report on the number of cross-matched transitions for each repository and compare their fundamental atomic parameters. We find differences in log(gf) values of up to 2 dex or more. We also find and report that 2% of our line list and Vienna atomic line database retrievals are composed of duplicate transitions. Finally we provide a number of examples of atomic spectral lines with different retrieved literature log(gf) values, and discuss the impact of these uncertain log(gf) values on quantitative spectroscopy. All cross-matched atomic data and duplicate transition pairs are available to download at http://brass.sdf.org

  14. NATIONAL GEOSCIENCE DATA REPOSITORY SYSTEM PHASE III: IMPLEMENTATION AND OPERATION ON THE REPOSITORY

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Marcus Milling

    2001-10-01

    The NGDRS has attained 72% of its targeted goal for cores and cuttings transfers, with over 12 million linear feet of cores and cuttings, in addition to large numbers of paleontological samples and are now available for public use. Additionally, large-scale transfers of seismic data have been evaluated, but based on the recommendation of the NGDRS steering committee, cores have been given priority because of the vast scale of the seismic data problem relative to the available funding. The rapidly changing industry conditions have required that the primary core and cuttings preservation strategy evolve as well. Additionally, the NGDRS clearinghousemore » is evaluating the viability of transferring seismic data covering the western shelf of the Florida Gulf Coast. AGI remained actively involved in assisting the National Research Council with background materials and presentations for their panel convened to study the data preservation issue. A final report of the panel is expected in early 2002. GeoTrek has been ported to Linux and MySQL, ensuring a purely open-source version of the software. This effort is key in ensuring long-term viability of the software so that is can continue basic operation regardless of specific funding levels. Work has commenced on a major revision of GeoTrek, using the open-source MapServer project and its related MapScript language. This effort will address a number of key technology issues that appear to be rising for 2002, including the discontinuation of the use of Java in future Microsoft operating systems. Discussions have been held regarding establishing potential new public data repositories, with hope for final determination in 2002.« less

  15. Gamma-ray spectrometry method used for radioactive waste drums characterization for final disposal at National Repository for Low and Intermediate Radioactive Waste--Baita, Romania.

    PubMed

    Done, L; Tugulan, L C; Dragolici, F; Alexandru, C

    2014-05-01

    The Radioactive Waste Management Department from IFIN-HH, Bucharest, performs the conditioning of the institutional radioactive waste in concrete matrix, in 200 l drums with concrete shield, for final disposal at DNDR - Baita, Bihor county, in an old exhausted uranium mine. This paper presents a gamma-ray spectrometry method for the characterization of the radioactive waste drums' radionuclides content, for final disposal. In order to study the accuracy of the method, a similar concrete matrix with Portland cement in a 200 l drum was used. © 2013 The Authors. Published by Elsevier Ltd All rights reserved.

  16. The Environmental Data Initiative: A broad-use data repository for environmental and ecological data that strives to balance data quality and ease of submission

    NASA Astrophysics Data System (ADS)

    Servilla, M. S.; Brunt, J.; Costa, D.; Gries, C.; Grossman-Clarke, S.; Hanson, P. C.; O'Brien, M.; Smith, C.; Vanderbilt, K.; Waide, R.

    2017-12-01

    In the world of data repositories, there seems to be a never ending struggle between the generation of high-quality data documentation and the ease of archiving a data product in a repository - the higher the documentation standards, the greater effort required by the scientist, and the less likely the data will be archived. The Environmental Data Initiative (EDI) attempts to balance the rigor of data documentation to the amount of effort required by a scientist to upload and archive data. As an outgrowth of the LTER Network Information System, the EDI is funded by the US NSF Division of Environmental Biology, to support the LTER, LTREB, OBFS, and MSB programs, in addition to providing an open data archive for environmental scientists without a viable archive. EDI uses the PASTA repository software, developed originally by the LTER. PASTA is metadata driven and documents data with the Ecological Metadata Language (EML), a high-fidelity standard that can describe all types of data in great detail. PASTA incorporates a series of data quality tests to ensure that data are correctly documented with EML in a process that is termed "metadata and data congruence", and incongruent data packages are forbidden in the repository. EDI reduces the burden of data documentation on scientists in two ways: first, EDI provides hands-on assistance in data documentation best practices using R and being developed in Python, for generating EML. These tools obscure the details of EML generation and syntax by providing a more natural and contextual setting for describing data. Second, EDI works closely with community information managers in defining rules used in PASTA quality tests. Rules deemed too strict can be turned off completely or just issue a warning, while the community learns to best handle the situation and improve their documentation practices. Rules can also be added or refined over time to improve overall quality of archived data. The outcome of quality tests are stored as part of the data archive in PASTA and are accessible to all users of the EDI data repository. In summary, EDI's metadata support to scientists and the comprehensive set of data quality tests for metadata and data congruency provide an ideal archive for environmental and ecological data.

  17. CellLineNavigator: a workbench for cancer cell line analysis

    PubMed Central

    Krupp, Markus; Itzel, Timo; Maass, Thorsten; Hildebrandt, Andreas; Galle, Peter R.; Teufel, Andreas

    2013-01-01

    The CellLineNavigator database, freely available at http://www.medicalgenomics.org/celllinenavigator, is a web-based workbench for large scale comparisons of a large collection of diverse cell lines. It aims to support experimental design in the fields of genomics, systems biology and translational biomedical research. Currently, this compendium holds genome wide expression profiles of 317 different cancer cell lines, categorized into 57 different pathological states and 28 individual tissues. To enlarge the scope of CellLineNavigator, the database was furthermore closely linked to commonly used bioinformatics databases and knowledge repositories. To ensure easy data access and search ability, a simple data and an intuitive querying interface were implemented. It allows the user to explore and filter gene expression, focusing on pathological or physiological conditions. For a more complex search, the advanced query interface may be used to query for (i) differentially expressed genes; (ii) pathological or physiological conditions; or (iii) gene names or functional attributes, such as Kyoto Encyclopaedia of Genes and Genomes pathway maps. These queries may also be combined. Finally, CellLineNavigator allows additional advanced analysis of differentially regulated genes by a direct link to the Database for Annotation, Visualization and Integrated Discovery (DAVID) Bioinformatics Resources. PMID:23118487

  18. Digital Rocks Portal: Preservation, Sharing, Remote Visualization and Automated Analysis of Imaged Datasets

    NASA Astrophysics Data System (ADS)

    Prodanovic, M.; Esteva, M.; Ketcham, R. A.; Hanlon, M.; Pettengill, M.; Ranganath, A.; Venkatesh, A.

    2016-12-01

    Due to advances in imaging modalities such as X-ray microtomography and scattered electron microscopy, 2D and 3D imaged datasets of rock microstructure on nanometer to centimeter length scale allow investigation of nonlinear flow and mechanical phenomena using numerical approaches. This in turn produces various upscaled parameters required by subsurface flow and deformation simulators. However, a single research group typically specializes in an imaging modality and/or related modeling on a single length scale, and lack of data-sharing infrastructure makes it difficult to integrate different length scales. We developed a sustainable, open and easy-to-use repository called the Digital Rocks Portal (http://www.digitalrocksportal.org), that (1) organizes images and related experimental measurements of different porous materials, (2) improves access to them for a wider community of geosciences or engineering researchers not necessarily trained in computer science or data analysis. Our objective is to enable scientific inquiry and engineering decisions founded on a data-driven basis. We show how the data loaded in the portal can be documented, referenced in publications via digital object identifiers, visualize and linked to other repositories. We then show preliminary results on integrating remote parallel visualization and flow simulation workflow with the pore structures currently stored in the repository. We finally discuss the issues of collecting correct metadata, data discoverability and repository sustainability. This is the first repository for this particular data, but is part of the wider ecosystem of geoscience data and model cyber-infrastructure called "Earthcube" (http://earthcube.org/) sponsored by National Science Foundation. For data sustainability and continuous access, the portal is implemented within the reliable, 24/7 maintained High Performance Computing Infrastructure supported by the Texas Advanced Computing Center (TACC) at the University of Texas at Austin. Long-term storage is provided through the University of Texas System Research Cyber-infrastructure initiative.

  19. Good Data Can Be Better Data - How Data Management Maturity Can Help Repositories Improve Operations, Data Quality, And Usability, Helping Researchers

    NASA Astrophysics Data System (ADS)

    Stall, S.

    2015-12-01

    Much earth and space science data and metadata are managed and supported by an infrastructure of repositories, ranging from large agency or instrument facilities, to institutions, to smaller repositories including labs. Scientists face many challenges in this ecosystem both on storing their data and in accessing data from others for new research. Critical for all uses is ensuring the credibility and integrity of the data and conveying that and provenance information now and in the future. Accurate information is essential for future researchers to find (or discover) the data, evaluate the data for use (content, temporal, geolocation, precision) and finally select (or discard) that data as meeting a "fit-for-purpose" criteria. We also need to optimize the effort it takes in describing the data for these determinations, which means making it efficient for the researchers who collect the data. At AGU we are developing a program aimed at helping repositories, and thereby researchers, improve data quality and data usability toward these goals. AGU has partnered with the CMMI Institute to develop their Data Management Maturity (DMM) framework within the Earth and space sciences. The CMMI DMM framework guides best practices in a range of data operations, and the application of the DMM, through an assessment, reveals how repositories and institutions can best optimize efforts to improve operations and functionality throughout the data lifecycle and elevate best practices across a variety of data management operations. Supporting processes like data operations, data governance, and data architecture are included. An assessment involves identifying accomplishment, and weaknesses compared to leading practices for data management. Broad application of the DMM can help improve quality in data and operations, and consistency across the community that will facilitate interoperability, discovery, preservation, and reuse. Good data can be better data. Consistency results in sustainability.

  20. International Approaches for Nuclear Waste Disposal in Geological Formations: Report on Fifth Worldwide Review

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Faybishenko, Boris; Birkholzer, Jens; Persoff, Peter

    2016-09-01

    The goal of the Fifth Worldwide Review is to document evolution in the state-of-the-art of approaches for nuclear waste disposal in geological formations since the Fourth Worldwide Review that was released in 2006. The last ten years since the previous Worldwide Review has seen major developments in a number of nations throughout the world pursuing geological disposal programs, both in preparing and reviewing safety cases for the operational and long-term safety of proposed and operating repositories. The countries that are approaching implementation of geological disposal will increasingly focus on the feasibility of safely constructing and operating their repositories in short-more » and long terms on the basis existing regulations. The WWR-5 will also address a number of specific technical issues in safety case development along with the interplay among stakeholder concerns, technical feasibility, engineering design issues, and operational and post-closure safety. Preparation and publication of the Fifth Worldwide Review on nuclear waste disposal facilitates assessing the lessons learned and developing future cooperation between the countries. The Report provides scientific and technical experiences on preparing for and developing scientific and technical bases for nuclear waste disposal in deep geologic repositories in terms of requirements, societal expectations and the adequacy of cases for long-term repository safety. The Chapters include potential issues that may arise as repository programs mature, and identify techniques that demonstrate the safety cases and aid in promoting and gaining societal confidence. The report will also be used to exchange experience with other fields of industry and technology, in which concepts similar to the design and safety cases are applied, as well to facilitate the public perception and understanding of the safety of the disposal approaches relative to risks that may increase over long times frames in the absence of a successful implementation of final dispositioning.« less

  1. Hybrid Multiagent System for Automatic Object Learning Classification

    NASA Astrophysics Data System (ADS)

    Gil, Ana; de La Prieta, Fernando; López, Vivian F.

    The rapid evolution within the context of e-learning is closely linked to international efforts on the standardization of learning object metadata, which provides learners in a web-based educational system with ubiquitous access to multiple distributed repositories. This article presents a hybrid agent-based architecture that enables the recovery of learning objects tagged in Learning Object Metadata (LOM) and provides individualized help with selecting learning materials to make the most suitable choice among many alternatives.

  2. A Unique Digital Electrocardiographic Repository for the Development of Quantitative Electrocardiography and Cardiac Safety: The Telemetric and Holter ECG Warehouse (THEW)

    PubMed Central

    Couderc, Jean-Philippe

    2010-01-01

    The sharing of scientific data reinforces open scientific inquiry; it encourages diversity of analysis and opinion while promoting new research and facilitating the education of next generations of scientists. In this article, we present an initiative for the development of a repository containing continuous electrocardiographic information and their associated clinical information. This information is shared with the worldwide scientific community in order to improve quantitative electrocardiology and cardiac safety. First, we present the objectives of the initiative and its mission. Then, we describe the resources available in this initiative following three components: data, expertise and tools. The Data available in the Telemetric and Holter ECG Warehouse (THEW) includes continuous ECG signals and associated clinical information. The initiative attracted various academic and private partners whom expertise covers a large list of research arenas related to quantitative electrocardiography; their contribution to the THEW promotes cross-fertilization of scientific knowledge, resources, and ideas that will advance the field of quantitative electrocardiography. Finally, the tools of the THEW include software and servers to access and review the data available in the repository. To conclude, the THEW is an initiative developed to benefit the scientific community and to advance the field of quantitative electrocardiography and cardiac safety. It is a new repository designed to complement the existing ones such as Physionet, the AHA-BIH Arrhythmia Database, and the CSE database. The THEW hosts unique datasets from clinical trials and drug safety studies that, so far, were not available to the worldwide scientific community. PMID:20863512

  3. Randomized, Paired-Site Comparison of Autologous Engineered Skin Substitutes and Split-Thickness Skin Graft for Closure of Extensive, Full-Thickness Burns.

    PubMed

    Boyce, Steven T; Simpson, Peggy S; Rieman, Mary T; Warner, Petra M; Yakuboff, Kevin P; Bailey, J Kevin; Nelson, Judith K; Fowler, Laura A; Kagan, Richard J

    Stable closure of full-thickness burn wounds remains a limitation to recovery from burns of greater than 50% of the total body surface area (TBSA). Hypothetically, engineered skin substitutes (ESS) consisting of autologous keratinocytes and fibroblasts attached to collagen-based scaffolds may reduce requirements for donor skin, and decrease mortality. ESS were prepared from split-thickness skin biopsies collected after enrollment of 16 pediatric burn patients into an approved study protocol. ESS and split-thickness autograft (AG) were applied to 15 subjects with full-thickness burns involving a mean of 76.9% TBSA. Data consisted of photographs, tracings of donor skin and healed wounds, comparison of mortality with the National Burn Repository, correlation of TBSA closed wounds with TBSA full-thickness burn, frequencies of regrafting, and immunoreactivity to the biopolymer scaffold. One subject expired before ESS application, and 15 subjects received 2056 ESS grafts. The ratio of closed wound to donor areas was 108.7 ± 9.7 for ESS compared with a maximum of 4.0 ± 0.0 for AG. Mortality for enrolled subjects was 6.25%, and 30.3% for a comparable population from the National Burn Repository (P < .05). Engraftment was 83.5 ± 2.0% for ESS and 96.5 ± 0.9% for AG. Percentage TBSA closed was 29.9 ± 3.3% for ESS, and 47.0 ± 2.0% for AG. These values were significantly different between the graft types. Correlation of % TBSA closed with ESS with % TBSA full-thickness burn generated an R value of 0.65 (P < .001). These results indicate that autologous ESS reduce mortality and requirements for donor skin harvesting, for grafting of full-thickness burns of greater than 50% TBSA.

  4. The Rail Alignment Environmental Impact Statement: An Update

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    R. Sweeney

    2005-01-20

    On July 23,2002, the President of the United States signed into law a joint resolution of the United States Congress designating the Yucca Mountain site in Nye County, Nevada, for development as a geologic repository for the disposal of spent nuclear fuel and high-level radioactive waste. If the US. Nuclear Regulatory Commission authorizes construction of the repository and receipt and possession of spent nuclear fuel and high-level radioactive at Yucca Mountain, the U.S. Department of Energy (DOE) would be responsible for transporting these materials to the Yucca Mountain repository as part of its obligation under the Nuclear Waste Policy Act.more » Part of the site recommendation decision included the analysis of a nation-wide shipping campaign to the proposed repository site. The ''Final Environmental Impact Statement for a Geologic Repository for the Disposal of Spent Nuclear Fuel and High-Level Radioactive Waste at Yucca Mountain, Nye County, Nevada'' (February 2002) (Repository EIS) evaluated the potential impacts of the transportation of 70,000 Metric Tons of Heavy Metal spent nuclear fuel and high-level radioactive waste from 77 locations around the nation to the potential repository in Nevada over a 24 year shipping campaign. In the Repository EIS, DOE identified mostly rail as its preferred mode of transportation, both nationally and in the State of Nevada. In December 2003, based on public comments and the environmental analyses in the Repository EIS, DOE identified a preference for the Caliente rail corridor in Nevada. On April 8, 2004, DOE issued a Record of Decision (ROD) on the Mode of Transportation and Nevada Rail Corridor for the Disposal of Spent Nuclear Fuel and High-Level Radioactive Waste at Yucca Mountain, Nye County, Nevada. In this ROD, the DOE announced that it had decided to select the mostly rail scenario analyzed in the Repository EIS as the transportation mode both on a national basis and in the State of Nevada. Under the mostly rail scenario, the DOE would rely on a combination of rail, truck and possibly barge to transport to the repository site at Yucca Mountain up to 70,000 MTHM of spent nuclear fuel and high-level radioactive waste, with most of the spent nuclear fuel and high-level radioactive waste being transported by rail. This will ultimately require construction of a rail line in Nevada to the repository. In addition, the DOE has decided to select the Caliente rail corridor in which to examine potential alignments within which to construct that rail line. A corridor is a strip of land, approximately 400 meters (0.25 miles) wide, that encompasses one of several possible routes through which DOE could build a rail line. An alignment is the specific location of a rail line in a corridor, and would likely be 60 meters [200 feet] or less in width. Also on April 8, 2004, DOE issued a Notice of Intent to Prepare an Environmental Impact Statement for the Alignment, Construction, and Operation of a Rail Line to a Geologic Repository at Yucca Mountain, Nye County, NV. In the Notice of Intent, the Department announced its intent to prepare a Rail Alignment EIS to assist in selecting a possible alignment for construction of a rail line that would connect the repository at Yucca Mountain to an existing main rail line in Nevada. The Rail Alignment EIS also would consider the potential construction and operation of a rail-to-truck intermodal transfer facility, proposed to be located at the confluence of an existing mainline railroad and a highway, to support legal-weight truck transportation until the rail system is fully operational. This corridor is approximately 513 kilometers (319 miles) long and would cost an estimated $880 million (2001 dollars). Should DOE decide to build the Caliente corridor, it may be the longest rail line built in the United States since the Transcontinental Railroad was constructed in 1869. Some of the challenges in building this rail corridor are steep grades (the corridor crosses over 7 mountain ranges), isolated terrain, possible tunnels, and stakeholder acceptance.« less

  5. Drilling effect on subsurface microbial community structure in groundwater from the -250 m gallery at the Horonobe Underground Research Laboratory, Japan

    NASA Astrophysics Data System (ADS)

    Ise, K.; Amano, Y.; Sasaki, Y.; Yoshikawa, H.

    2014-12-01

    The deep geological disposal system is regarded as the most secure and practical disposal method of high-level radioactive waste in the world. In this disposal system, preservation of reducing condition is one of the key requirements, because most of radionuclides have low solubilities in such condition. However, the host rocks near the shafts and galleries would be affected by oxidization during the construction and operation period of a repository (for about 50 years). Therefore, the recovery of reducing condition after closing the repository should be verified. During the recovery processes, it is considered that microbial activities play important roles, but the mechanisms are poorly understood. In this study, we monitored the changes in microbial communities by molecular method to evaluate microbial response toward the oxygen stress. The groundwater samples were collected from a borehole of 250 m depth at the Horonobe Underground Research Laboratory, for two years immediately after drilling of a borehole without any contamination as much as possible. Immediately after drilling of the borehole, the phylotype related to Arcobacter spp. was dominated about 65 % of the total clone library. Arcobacter spp. is known as sulfide oxidizer and which can growth chemoautotrophically. Half a year later, the phylotype related to Azoarcus spp. and Pseudomonas spp. known as nitrate reducing bacteria increased, instead of the phylotype related to Arcobacter spp. One year later, in addition to nitrate reducing bacteria, phylotype related to Dethiobacterspp. known as thiosulfate reducing bacteria was dominantly detected. Two years later, most of detected clones were related to uncultured species such as candidate division WS6 and JS1 which are detected frequently in deep-sea sediments. Our results indicate that these redox sequential reactions could contribute to the recovery and maintenance of reducing conditions and provide a conceptual model for evaluating the capacity to recover reducing conditions in subsurface environments after final geological disposal and the post-closure.

  6. A Record of Uranium-Series Transport in Fractured, Unsaturated Tuff at Nopal I, Sierra Peña Blanca, Chihuahua, Mexico

    NASA Astrophysics Data System (ADS)

    Denton, J.; Goldstein, S. J.; Paviet, P.; Nunn, A. J.; Amato, R. S.; Hinrichs, K. A.

    2015-12-01

    In this study we utilize U-series disequilibria measurements to investigate mineral fluid interactions and the role fractures play in the geochemical evolution of an analogue for a high level nuclear waste repository, the Nopal I uranium ore deposit. Samples of fracture-fill materials have been collected from a vertical drill core and surface fractures. High uranium concentrations in these materials (12-7700 ppm) indicate U mobility and transport from the deposit in the past. U concentrations generally decrease with horizontal distance away from the ore deposit but show no trend with depth. Isotopic activity ratios indicate a complicated geochemical evolution in terms of the timing and extent of actinide mobility, possibly due to changing environmental (redox) conditions over the history of the deposit. 234U/238U activity ratios are generally distinct from secular equilibrium and indicate some degree of open system U behavior during the past 1.2 Ma. However, calculated closed system 238U-234U-230Th model ages are generally >313 ka and >183 ka for the surface fracture and drill core samples respectively, suggesting closed system behavior for U and Th over this most recent time period. Whole rock isochrons drawn for the drill core samples show that at two of three depths fractures have remained closed with respect to U and Th mobility for >200 ka. However, open system behavior for U in the last 350 ka is suggested at 67 m depth. 231Pa/235U activity ratios within error of unity suggest closed system behavior for U and Pa for at least the past 185 ka. 226Ra/230Th activity ratios are typically <1 (0.7-1.2), suggesting recent (<8 ka) radium loss and mobility due to ongoing fluid flow in the fractures. Overall, the mainly closed system behavior of U-Th-Pa over the past ~200 ka provides one indicator of the geochemical immobility of these actinides over long time-scales for potential nuclear waste repositories sited in fractured, unsaturated tuff.

  7. Eliciting Disease Data from Wikipedia Articles.

    PubMed

    Fairchild, Geoffrey; Del Valle, Sara Y; De Silva, Lalindra; Segre, Alberto M

    2015-05-01

    Traditional disease surveillance systems suffer from several disadvantages, including reporting lags and antiquated technology, that have caused a movement towards internet-based disease surveillance systems. Internet systems are particularly attractive for disease outbreaks because they can provide data in near real-time and can be verified by individuals around the globe. However, most existing systems have focused on disease monitoring and do not provide a data repository for policy makers or researchers. In order to fill this gap, we analyzed Wikipedia article content. We demonstrate how a named-entity recognizer can be trained to tag case counts, death counts, and hospitalization counts in the article narrative that achieves an F1 score of 0.753. We also show, using the 2014 West African Ebola virus disease epidemic article as a case study, that there are detailed time series data that are consistently updated that closely align with ground truth data. We argue that Wikipedia can be used to create the first community-driven open-source emerging disease detection, monitoring, and repository system.

  8. The repository-based software engineering program: Redefining AdaNET as a mainstream NASA source

    NASA Technical Reports Server (NTRS)

    1993-01-01

    The Repository-based Software Engineering Program (RBSE) is described to inform and update senior NASA managers about the program. Background and historical perspective on software reuse and RBSE for NASA managers who may not be familiar with these topics are provided. The paper draws upon and updates information from the RBSE Concept Document, baselined by NASA Headquarters, Johnson Space Center, and the University of Houston - Clear Lake in April 1992. Several of NASA's software problems and what RBSE is now doing to address those problems are described. Also, next steps to be taken to derive greater benefit from this Congressionally-mandated program are provided. The section on next steps describes the need to work closely with other NASA software quality, technology transfer, and reuse activities and focuses on goals and objectives relative to this need. RBSE's role within NASA is addressed; however, there is also the potential for systematic transfer of technology outside of NASA in later stages of the RBSE program. This technology transfer is discussed briefly.

  9. Eliciting Disease Data from Wikipedia Articles

    PubMed Central

    Fairchild, Geoffrey; Del Valle, Sara Y.; De Silva, Lalindra; Segre, Alberto M.

    2017-01-01

    Traditional disease surveillance systems suffer from several disadvantages, including reporting lags and antiquated technology, that have caused a movement towards internet-based disease surveillance systems. Internet systems are particularly attractive for disease outbreaks because they can provide data in near real-time and can be verified by individuals around the globe. However, most existing systems have focused on disease monitoring and do not provide a data repository for policy makers or researchers. In order to fill this gap, we analyzed Wikipedia article content. We demonstrate how a named-entity recognizer can be trained to tag case counts, death counts, and hospitalization counts in the article narrative that achieves an F1 score of 0.753. We also show, using the 2014 West African Ebola virus disease epidemic article as a case study, that there are detailed time series data that are consistently updated that closely align with ground truth data. We argue that Wikipedia can be used to create the first community-driven open-source emerging disease detection, monitoring, and repository system. PMID:28721308

  10. Implementation of an OAIS Repository Using Free, Open Source Software

    NASA Astrophysics Data System (ADS)

    Flathers, E.; Gessler, P. E.; Seamon, E.

    2015-12-01

    The Northwest Knowledge Network (NKN) is a regional data repository located at the University of Idaho that focuses on the collection, curation, and distribution of research data. To support our home institution and others in the region, we offer services to researchers at all stages of the data lifecycle—from grant application and data management planning to data distribution and archive. In this role, we recognize the need to work closely with other data management efforts at partner institutions and agencies, as well as with larger aggregation efforts such as our state geospatial data clearinghouses, data.gov, DataONE, and others. In the past, one of our challenges with monolithic, prepackaged data management solutions is that customization can be difficult to implement and maintain, especially as new versions of the software are released that are incompatible with our local codebase. Our solution is to break the monolith up into its constituent parts, which offers us several advantages. First, any customizations that we make are likely to fall into areas that can be accessed through Application Program Interfaces (API) that are likely to remain stable over time, so our code stays compatible. Second, as components become obsolete or insufficient to meet new demands that arise, we can replace the individual components with minimal effect on the rest of the infrastructure, causing less disruption to operations. Other advantages include increased system reliability, staggered rollout of new features, enhanced compatibility with legacy systems, reduced dependence on a single software company as a point of failure, and the separation of development into manageable tasks. In this presentation, we describe our application of the Service Oriented Architecture (SOA) design paradigm to assemble a data repository that conforms to the Open Archival Information System (OAIS) Reference Model primarily using a collection of free and open-source software. We detail the design of the repository, based upon open standards to support interoperability with other institutions' systems and with future versions of our own software components. We also describe the implementation process, including our use of GitHub as a collaboration tool and code repository.

  11. Reproducible Research in the Geosciences at Scale: Achievable Goal or Elusive Dream?

    NASA Astrophysics Data System (ADS)

    Wyborn, L. A.; Evans, B. J. K.

    2016-12-01

    Reproducibility is a fundamental tenant of the scientific method: it implies that any researcher, or a third party working independently, can duplicate any experiment or investigation and produce the same results. Historically computationally based research involved an individual using their own data and processing it in their own private area, often using software they wrote or inherited from close collaborators. Today, a researcher is likely to be part of a large team that will use a subset of data from an external repository and then process the data on a public or private cloud or on a large centralised supercomputer, using a mixture of their own code, third party software and libraries, or global community codes. In 'Big Geoscience' research it is common for data inputs to be extracts from externally managed dynamic data collections, where new data is being regularly appended, or existing data is revised when errors are detected and/or as processing methods are improved. New workflows increasingly use services to access data dynamically to create subsets on-the-fly from distributed sources, each of which can have a complex history. At major computational facilities, underlying systems, libraries, software and services are being constantly tuned and optimised, or as new or replacement infrastructure being installed. Likewise code used from a community repository is continually being refined, re-packaged and ported to the target platform. To achieve reproducibility, today's researcher increasingly needs to track their workflow, including querying information on the current or historical state of facilities used. Versioning methods are standard practice for software repositories or packages, but it is not common for either data repositories or data services to provide information about their state, or for systems to provide query-able access to changes in the underlying software. While a researcher can achieve transparency and describe steps in their workflow so that others can repeat them and replicate processes undertaken, they cannot achieve exact reproducibility or even transparency of results generated. In Big Geoscience, full reproducibiliy will be an elusive dream until data repositories and compute facilities can provide provenance information in a standards compliant, machine query-able way.

  12. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Klein, Thomas; Patterson, Russell; Camphouse, Chris

    There are two primary regulatory requirements for Panel Closures at the Waste Isolation Pilot Plant (WIPP), the nation's only deep geologic repository for defense related Transuranic (TRU) and Mixed TRU waste. The Federal requirement is through 40 CFR 191 and 194, promulgated by the U.S. Environmental Protection Agency (EPA). The state requirement is regulated through the authority of the Secretary of the New Mexico Environment Department (NMED) under the New Mexico Hazardous Waste Act (HWA), New Mexico Statutes Annotated (NMSA) 1978, chap. 74-4-1 through 74-4-14, in accordance with the New Mexico Hazardous Waste Management Regulations (HWMR), 20.4.1 New Mexico Annotatedmore » Code (NMAC). The state regulations are implemented for the operational period of waste emplacement plus 30 years whereas the federal requirements are implemented from the operational period through 10,000 years. The 10,000 year federal requirement is related to the adequate representation of the panel closures in determining long-term performance of the repository. In Condition 1 of the Final Certification Rulemaking for 40 CFR Part 194, the EPA required a specific design for the panel closure system. The U.S. Department of Energy (DOE) Carlsbad Field Office (CBFO) has requested, through the Planned Change Request (PCR) process, that the EPA modify Condition 1 via its rulemaking process. The DOE has also requested, through the Permit Modification Request (PMR) process, that the NMED modify the approved panel closure system specified in Permit Attachment G1. The WIPP facility is carved out of a bedded salt formation 655 meters below the surface of southeast New Mexico. Condition 1 of the Final Certification Rulemaking specifies that the waste panels be closed using Option D which is a combination of a Salado mass concrete (SMC) monolith and an isolation/explosion block wall. The Option D design was also accepted as the panel closure of choice by the NMED. After twelve years of waste handling operations and a greater understanding of the waste and the behavior of the underground salt formation, the DOE has established a revised panel closure design. This revised design meets both the short-term NMED Permit requirements for the operational period, and also the Federal requirements for long-term repository performance. This new design is simpler, easier to construct and has less of an adverse impact on waste disposal operations than the originally approved Option D design. The Panel Closure Redesign is based on: (1) the results of in-situ constructability testing performed to determine run-of-mine salt reconsolidation parameters and how the characteristics of the bedded salt formation affect these parameters and, (2) the results of air flow analysis of the new design to determine that the limit for the migration of Volatile Organic Compounds (VOCs) will be met at the compliance point. Waste panel closures comprise a repository feature that has been represented in WIPP performance assessment (PA) since the original Compliance Certification Application of 1996. Panel closures are included in WIPP PA models principally because they are a part of the disposal system, not because they play a substantive role in inhibiting the release of radionuclides to the outside environment. The 1998 rulemaking that certified WIPP to receive transuranic waste placed conditions on the panel closure design to be implemented in the repository. The revised panel closure design, termed the Run-of-Mine (ROM) Panel Closure System (ROMPCS), is comprised of 30.48 meters of ROM salt with barriers at each end. The ROM salt is generated from ongoing mining operations at the WIPP and may be compacted and/or moistened as it is emplaced in a panel entry. The barriers consist of bulkheads, similar to those currently used in the panels as room closures. A WIPP performance assessment has been completed that incorporates the ROMPCS design into the representation of the repository, and compares repository performance to that achieved with the approved Option D design. Several key physical processes and rock mechanics principles are incorporated into the performance assessment. First, creep closure of the salt rock surrounding a panel entry results in consolidation of the ROM salt emplaced in the entry. Eventually, the ROM salt comprising the ROMPCS will approach a condition similar to intact salt. As the ROM salt reaches higher fractional densities during consolidation, back stress will be imposed on the surrounding rock mass leading to eventual healing of the disturbed rock zone above and below the panel closure. Healing of the disturbed rock zone above and below the ROMPCS reduces the porosity and permeability in those areas. Analysis of the new design demonstrates that: (1) the WIPP continues to meet regulatory compliance requirements when the ROMPCS design is implemented instead of Option D, and (2) there is no impact on the short-term effectiveness of the panel closure to limit the concentration of VOCs at the WIPP site boundary to a fraction of the health-based exposure limits (HBLs) during the operational period. (authors)« less

  13. Digital data preservation for scholarly publications in astronomy

    NASA Astrophysics Data System (ADS)

    Choudhury, Sayeed; di Lauro, Tim; Szalay, Alex; Vishniac, Ethan; Hanisch, Robert; Steffen, Julie; Milkey, Robert; Ehling, Teresa; Plante, Ray

    2007-11-01

    Astronomy is similar to other scientific disciplines in that scholarly publication relies on the presentation and interpretation of data. But although astronomy now has archives for its primary research telescopes and associated surveys, the highly processed data that is presented in the peer-reviewed journals and is the basis for final analysis and interpretation is generally not archived and has no permanent repository. We have initiated a project whose goal is to implement an end-to-end prototype system which, through a partnership of a professional society, that society's scholarly publications/publishers, research libraries, and an information technology substrate provided by the Virtual Observatory, will capture high-level digital data as part of the publication process and establish a distributed network of curated, permanent data repositories. The data in this network will be accessible through the research journals, astronomy data centers, and Virtual Observatory data discovery portals.

  14. EIR: enterprise imaging repository, an alternative imaging archiving and communication system.

    PubMed

    Bian, Jiang; Topaloglu, Umit; Lane, Cheryl

    2009-01-01

    The enormous number of studies performed at the Nuclear Medicine Department of University of Arkansas for Medical Sciences (UAMS) generates a huge amount PET/CT images daily. A DICOM workstation had been used as "mini-PACS" to route all studies, which is historically proven to be slow due to various reasons. However, replacing the workstation with a commercial PACS server is not only cost inefficient; and more often, the PACS vendors are reluctant to take responsibility for the final integration of these components. Therefore, in this paper, we propose an alternative imaging archiving and communication system called Enterprise Imaging Repository (EIR). EIR consists of two distinguished components: an image processing daemon and a user friendly web interface. EIR not only reduces the overall waiting time of transferring a study from the modalities to radiologists' workstations, but also provides a more preferable presentation.

  15. The NASA Ames Life Sciences Data Archive: Biobanking for the Final Frontier

    NASA Technical Reports Server (NTRS)

    Rask, Jon; Chakravarty, Kaushik; French, Alison J.; Choi, Sungshin; Stewart, Helen J.

    2017-01-01

    The NASA Ames Institutional Scientific Collection involves the Ames Life Sciences Data Archive (ALSDA) and a biospecimen repository, which are responsible for archiving information and non-human biospecimens collected from spaceflight and matching ground control experiments. The ALSDA also manages a biospecimen sharing program, performs curation and long-term storage operations, and facilitates distribution of biospecimens for research purposes via a public website (https:lsda.jsc.nasa.gov). As part of our best practices, a tissue viability testing plan has been developed for the repository, which will assess the quality of samples subjected to long-term storage. We expect that the test results will confirm usability of the samples, enable broader science community interest, and verify operational efficiency of the archives. This work will also support NASA open science initiatives and guides development of NASA directives and policy for curation of biological collections.

  16. Tale taming radioactive fears: Linking nuclear waste disposal to the "continuum of the good".

    PubMed

    Yli-Kauhaluoma, Sari; Hänninen, Hannu

    2014-04-01

    We examine how the constructor of the world's first repository for the final disposal of spent nuclear fuel in Eurajoki, Finland, aims to shape lay understanding of the facility's risks and to tame the nuclear fears of the local community by producing positive associations, imagery and tales. Our empirical material consists of the constructor's newsletters targeted mainly at the local residents. In the narrative analysis, we identified a storyline where the construction of the repository is linked into the "continuum of the good" in the municipality of the construction site and the surrounding areas. The storyline consists of five different themes all emphasizing the "continuum of the good" in the area: cultural heritage, well-being, developing expertise, natural environment, and local families. Our study contributes to the literature on pro-nuclear storytelling by showing how the inclination is towards narratives that are constructed around local symbols, cultural landmarks, and institutions.

  17. Environmental assessment: Yucca Mountain site, Nevada research and development area, Nevada; Volume 1

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    1986-05-01

    In February 1983, the US Department of Energy (DOE) identified the Yucca Mountain site in Nevada as one of nine potentially acceptable sites for a mined geologic repository for spent nuclear fuel and high- level radioactive waste. The site is in the Great Basin, which is one of five distinct geohydrologic settings considered for the first repository. To determine their suitability, the Yucca Mountain site and the eight other potentially acceptable sites have been evaluated in accordance with the DOE`s General Guideline for the Recommendation of Sites for the Nuclear Waste Repositories. These evaluations were reported in draft environmental assessmentsmore » (EA), which were issued for public review and comment. After considering the comments received on the draft EAs, the DOE prepared the final EAs. On the basis of the evaluations reported in this EA, the DOE found that the Yucca Mountain site is not disqualified under the guidelines. The DOE has also found that it is suitable for site characterization because the evidence does not support a conclusion that the site will not be able to meet each of the qualifying conditions specified in the guidelines. On the basis of these findings, the DOE is nominating the Yucca Mountain site as of five sites suitable for characterization.« less

  18. Designing for Change: Interoperability in a scaling and adapting environment

    NASA Astrophysics Data System (ADS)

    Yarmey, L.

    2015-12-01

    The Earth Science cyberinfrastructure landscape is constantly changing. Technologies advance and technical implementations are refined or replaced. Data types, volumes, packaging, and use cases evolve. Scientific requirements emerge and mature. Standards shift while systems scale and adapt. In this complex and dynamic environment, interoperability remains a critical component of successful cyberinfrastructure. Through the resource- and priority-driven iterations on systems, interfaces, and content, questions fundamental to stable and useful Earth Science cyberinfrastructure arise. For instance, how are sociotechnical changes planned, tracked, and communicated? How should operational stability balance against 'new and shiny'? How can ongoing maintenance and mitigation of technical debt be managed in an often short-term resource environment? The Arctic Data Explorer is a metadata brokering application developed to enable discovery of international, interdisciplinary Arctic data across distributed repositories. Completely dependent on interoperable third party systems, the Arctic Data Explorer publicly launched in 2013 with an original 3000+ data records from four Arctic repositories. Since then the search has scaled to 25,000+ data records from thirteen repositories at the time of writing. In the final months of original project funding, priorities shift to lean operations with a strategic eye on the future. Here we present lessons learned from four years of Arctic Data Explorer design, development, communication, and maintenance work along with remaining questions and potential directions.

  19. Environmental assessment: Yucca Mountain site, Nevada research and development area, Nevada; Volume 3

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    1986-05-01

    In February 1983, the US Department of Energy (DOE) identified the Yucca Mountain site in Nevada as one of nine potentially acceptable sites for a mined geologic repository for spent nuclear fuel and high-level radioactive waste. The site is in the Great Basin, which is one of five distinct geohydrologic settings considered for the first repository. To determine their suitability, the Yucca Mountain site and the eight other potentially acceptable sites have been evaluated in accordance with the DOE`s General Guidelines for the Recommendation of Sites for the Nuclear Waste Repositories. These evaluations were reported in draft environmental assessments (EAs),more » which were issued for public review and comment. After considering the comments received on the draft EAs, the DOE prepared the final EAs. On the basis of the evaluations reported in this EA, the DOE has found that the Yucca Mountain site is not disqualified under the guidelines. The DOE has also found that it is suitable for site characterization because the evidence does not support a conclusion that the site will not be able to meet each of the qualifying conditions specified in the guidelines. On the basis of these findings, the DOE is nominating the Yucca Mountain site as one of five sites suitable for characterization.« less

  20. Environmental assessment: Richton Dome Site, Mississippi

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    none,

    1986-05-01

    In February 1983, the US Department of Energy (DOE) identified the Richton Dome site in Mississippi as one of the nine potentially acceptable sites for a mined geologic repository for spent nuclear fuel and high-level radioactive waste. To determine their suitability, the Richton Dome site and the eight other potentially acceptable sites have been evaluated in accordance with the DOE's General Guidelines for the Recommendation of Sites for the Nuclear Waste Repositories. These evaluations were reported in draft environmental assessments (EAs), which were issued for public review and comment. After considering the comments received on the draft EAs, the DOEmore » prepared the final EAs. The site is in the Gulf interior region, which is one of five distinct geohydrologic settings considered for the first repository. This setting contains two other potentially acceptable sites--the Cypress Creek Dome site in Mississippi and the Vacherie Dome site in Louisiana. Although the Cypress Creek Dome and the Vacherie Dome sites are suitable for site characterization, the DOE has concluded that the Richton Dome site is the preferred site in the Gulf interior region. On the basis of the evaluations reported in this EA, the DOE has found that the Richton Dome site is not disqualified under the guidelines.« less

  1. 'There is no turning back'--is AFIP facing demise?

    PubMed

    Seckinger, Daniel

    2005-08-01

    The U.S. Department of Defense has recommended that Walter Reed Army Medical Center, home of the Armed Forces Institute of Pathology, be relocated and that the AFIP's constituent parts be eliminated or, in the case of its tissue repository, warehoused. CAP past resident Daniel Seckinger, MD, chairman of the board of the American Registry of athology, testified July 7 before the Defense Base Closure and Realignment Commission its public hearing on military base closings. His statement appears here.

  2. 78 FR 49967 - Magnuson-Stevens Fishery Conservation and Management Act Provisions; Fisheries of the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-16

    ...: Final rule. SUMMARY: This final rule reopens an additional portion of the Georges Bank Closed Area to... interim final rule reopened a portion of the Georges Bank Closed Area that had been closed to the harvest... additional portion of the Georges Bank Closed Area. DATES: This rule is effective August 16, 2013. ADDRESSES...

  3. Grid Application Meta-Repository System: Repository Interconnectivity and Cross-domain Application Usage in Distributed Computing Environments

    NASA Astrophysics Data System (ADS)

    Tudose, Alexandru; Terstyansky, Gabor; Kacsuk, Peter; Winter, Stephen

    Grid Application Repositories vary greatly in terms of access interface, security system, implementation technology, communication protocols and repository model. This diversity has become a significant limitation in terms of interoperability and inter-repository access. This paper presents the Grid Application Meta-Repository System (GAMRS) as a solution that offers better options for the management of Grid applications. GAMRS proposes a generic repository architecture, which allows any Grid Application Repository (GAR) to be connected to the system independent of their underlying technology. It also presents applications in a uniform manner and makes applications from all connected repositories visible to web search engines, OGSI/WSRF Grid Services and other OAI (Open Archive Initiative)-compliant repositories. GAMRS can also function as a repository in its own right and can store applications under a new repository model. With the help of this model, applications can be presented as embedded in virtual machines (VM) and therefore they can be run in their native environments and can easily be deployed on virtualized infrastructures allowing interoperability with new generation technologies such as cloud computing, application-on-demand, automatic service/application deployments and automatic VM generation.

  4. Coupled Heat and Moisture Transport Simulation on the Re-saturation of Engineered Clay Barrier

    NASA Astrophysics Data System (ADS)

    Huang, W. H.; Chuang, Y. F.

    2014-12-01

    Engineered clay barrier plays a major role for the isolation of radioactive wastes in a underground repository. This paper investigates the resaturation processes of clay barrier, with emphasis on the coupling effects of heat and moisture during the intrusion of groundwater to the repository. A reference bentonite and a locally available clay were adopted in the laboratory program. Soil suction of clay specimens was measured by psychrometers embedded in clay specimens and by vapor equilibrium technique conducted at varying temperatures so as to determine the soil water characteristic curves of the two clays at different temperatures. And water uptake tests were conducted on clay specimens compacted at various densities to simulate the intrusion of groundwater into the clay barrier. Using the soil water characteristic curve, an integration scheme was introduced to estimate the hydraulic conductivity of unsaturated clay. It was found that soil suction decreases as temperature increases, resulting in a reduction in water retention capability. The finite element method was then employed to carry out the numerical simulation of the saturation process in the near field of a repository. Results of the numerical simulation were validated using the degree of saturation profile obtained from the water uptake tests on the clays. The numerical scheme was then extended to establish a model simulating the resaturation process after the closure of a repository. Finally, the model was then used to evaluate the effect of clay barrier thickness on the time required for groundwater to penetrate the clay barrier and approach saturation. Due to the variation in clay suction and thermal conductivity with temperature of clay barrier material, the calculated temperature field shows a reduction as a result of incorporating the hydro-properties in the calculations.

  5. 48 CFR 227.7207 - Contractor data repositories.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Computer Software and Computer Software Documentation 227.7207 Contractor data repositories. Follow 227.7108 when it is in the Government's interests to have a data repository include computer software or to have a separate computer software repository. Contractual instruments establishing the repository...

  6. 48 CFR 227.7207 - Contractor data repositories.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Computer Software and Computer Software Documentation 227.7207 Contractor data repositories. Follow 227.7108 when it is in the Government's interests to have a data repository include computer software or to have a separate computer software repository. Contractual instruments establishing the repository...

  7. 48 CFR 227.7207 - Contractor data repositories.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Computer Software and Computer Software Documentation 227.7207 Contractor data repositories. Follow 227.7108 when it is in the Government's interests to have a data repository include computer software or to have a separate computer software repository. Contractual instruments establishing the repository...

  8. 48 CFR 227.7207 - Contractor data repositories.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Computer Software and Computer Software Documentation 227.7207 Contractor data repositories. Follow 227.7108 when it is in the Government's interests to have a data repository include computer software or to have a separate computer software repository. Contractual instruments establishing the repository...

  9. 40 CFR 124.33 - Information repository.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 21 2010-07-01 2010-07-01 false Information repository. 124.33 Section... FOR DECISIONMAKING Specific Procedures Applicable to RCRA Permits § 124.33 Information repository. (a... basis, for an information repository. When assessing the need for an information repository, the...

  10. 10 CFR 60.130 - General considerations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... REPOSITORIES Technical Criteria Design Criteria for the Geologic Repository Operations Area § 60.130 General... for a high-level radioactive waste repository at a geologic repository operations area, and an... geologic repository operations area, must include the principal design criteria for a proposed facility...

  11. 48 CFR 227.7108 - Contractor data repositories.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Technical Data 227.7108 Contractor data repositories. (a) Contractor data repositories may be established... procedures for protecting technical data delivered to or stored at the repository from unauthorized release... disclosure of technical data from the repository to third parties consistent with the Government's rights in...

  12. 17 CFR 49.12 - Swap data repository recordkeeping requirements.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 17 Commodity and Securities Exchanges 1 2012-04-01 2012-04-01 false Swap data repository... COMMISSION SWAP DATA REPOSITORIES § 49.12 Swap data repository recordkeeping requirements. (a) A registered swap data repository shall maintain its books and records in accordance with the requirements of part...

  13. 17 CFR 49.12 - Swap data repository recordkeeping requirements.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 17 Commodity and Securities Exchanges 1 2013-04-01 2013-04-01 false Swap data repository... COMMISSION SWAP DATA REPOSITORIES § 49.12 Swap data repository recordkeeping requirements. (a) A registered swap data repository shall maintain its books and records in accordance with the requirements of part...

  14. 17 CFR 49.12 - Swap data repository recordkeeping requirements.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 17 Commodity and Securities Exchanges 2 2014-04-01 2014-04-01 false Swap data repository... COMMISSION (CONTINUED) SWAP DATA REPOSITORIES § 49.12 Swap data repository recordkeeping requirements. (a) A registered swap data repository shall maintain its books and records in accordance with the requirements of...

  15. 10 CFR 63.112 - Requirements for preclosure safety analysis of the geologic repository operations area.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... geologic repository operations area. 63.112 Section 63.112 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN A GEOLOGIC REPOSITORY AT YUCCA MOUNTAIN, NEVADA Technical... repository operations area. The preclosure safety analysis of the geologic repository operations area must...

  16. Managing and Evaluating Digital Repositories

    ERIC Educational Resources Information Center

    Zuccala, Alesia; Oppenheim, Charles; Dhiensa, Rajveen

    2008-01-01

    Introduction: We examine the role of the digital repository manager, discuss the future of repository management and evaluation and suggest that library and information science schools develop new repository management curricula. Method: Face-to-face interviews were carried out with managers of five different types of repositories and a Web-based…

  17. jPOSTrepo: an international standard data repository for proteomes

    PubMed Central

    Okuda, Shujiro; Watanabe, Yu; Moriya, Yuki; Kawano, Shin; Yamamoto, Tadashi; Matsumoto, Masaki; Takami, Tomoyo; Kobayashi, Daiki; Araki, Norie; Yoshizawa, Akiyasu C.; Tabata, Tsuyoshi; Sugiyama, Naoyuki; Goto, Susumu; Ishihama, Yasushi

    2017-01-01

    Major advancements have recently been made in mass spectrometry-based proteomics, yielding an increasing number of datasets from various proteomics projects worldwide. In order to facilitate the sharing and reuse of promising datasets, it is important to construct appropriate, high-quality public data repositories. jPOSTrepo (https://repository.jpostdb.org/) has successfully implemented several unique features, including high-speed file uploading, flexible file management and easy-to-use interfaces. This repository has been launched as a public repository containing various proteomic datasets and is available for researchers worldwide. In addition, our repository has joined the ProteomeXchange consortium, which includes the most popular public repositories such as PRIDE in Europe for MS/MS datasets and PASSEL for SRM datasets in the USA. Later MassIVE was introduced in the USA and accepted into the ProteomeXchange, as was our repository in July 2016, providing important datasets from Asia/Oceania. Accordingly, this repository thus contributes to a global alliance to share and store all datasets from a wide variety of proteomics experiments. Thus, the repository is expected to become a major repository, particularly for data collected in the Asia/Oceania region. PMID:27899654

  18. Software Technology for Adaptable, Reliable Systems (STARS). Repository Integration AdaKNET Software User’s Manual

    DTIC Science & Technology

    1990-10-03

    9 4.1. Mapping the Conceptual Model to the Implementation ................................................ 9 4.2. Overview of...browser-editor application. Finally, appendix A provides a detailed description of the AdaKNET conceptual model; users of AdaKNET should fami...provide a brief summary of the semantics of the underlying conceptual model implemented by AdaKNET, use of the AdaKNET ADT will require a more thorough

  19. Comparison of rule induction, decision trees and formal concept analysis approaches for classification

    NASA Astrophysics Data System (ADS)

    Kotelnikov, E. V.; Milov, V. R.

    2018-05-01

    Rule-based learning algorithms have higher transparency and easiness to interpret in comparison with neural networks and deep learning algorithms. These properties make it possible to effectively use such algorithms to solve descriptive tasks of data mining. The choice of an algorithm depends also on its ability to solve predictive tasks. The article compares the quality of the solution of the problems with binary and multiclass classification based on the experiments with six datasets from the UCI Machine Learning Repository. The authors investigate three algorithms: Ripper (rule induction), C4.5 (decision trees), In-Close (formal concept analysis). The results of the experiments show that In-Close demonstrates the best quality of classification in comparison with Ripper and C4.5, however the latter two generate more compact rule sets.

  20. Natural analogues for processes affecting disposal of high-level radioactive waste in the vadose zone

    NASA Astrophysics Data System (ADS)

    Stuckless, J. S.

    2003-04-01

    Natural analogues can contribute to understanding and predicting the performance of subsystems and processes affecting a mined geologic repository for high-level radioactive waste in several ways. Most importantly, analogues provide tests for various aspects of systems of a repository at dimensional scales and time spans that cannot be attained by experimental study. In addition, they provide a means for the general public to judge the predicted performance of a potential high-level nuclear waste repository in familiar terms such that the average person can assess the anticipated long-term performance and other scientific conclusions. Hydrologists working on the Yucca Mountain Project (currently the U.S. Department of Energy's Office of Repository Development) have modeled the flow of water through the vadose zone at Yucca Mountain, Nevada and particularly the interaction of vadose-zone water with mined openings. Analogues from both natural and anthropogenic examples confirm the prediction that most of the water moving through the vadose zone will move through the host rock and around tunnels. This can be seen both quantitatively where direct comparison between seepage and net infiltration has been made and qualitatively by the excellent degree of preservation of archaeologic artifacts in underground openings. The latter include Paleolithic cave paintings in southwestern Europe, murals and artifacts in Egyptian tombs, painted subterranean Buddhist temples in India and China, and painted underground churches in Cappadocia, Turkey. Natural analogues also suggest that this diversion mechanism is more effective in porous media than in fractured media. Observations from natural analogues are also consistent with the modeled decrease in the percentage of infiltration that becomes seepage with a decrease in amount of infiltration. Finally, analogues, such as tombs that have ben partially filled by mud flows, suggest that the same capillary forces that keep water in the rock around underground openings will draw water towards buried waste packages if they are encased in backfill. Analogue work in support of the U.S. repository program continues in the U.S. Geological Survey, in cooperation with the U.S. Department of Energy.

  1. A Tailored Ontology Supporting Sensor Implementation for the Maintenance of Industrial Machines.

    PubMed

    Maleki, Elaheh; Belkadi, Farouk; Ritou, Mathieu; Bernard, Alain

    2017-09-08

    The longtime productivity of an industrial machine is improved by condition-based maintenance strategies. To do this, the integration of sensors and other cyber-physical devices is necessary in order to capture and analyze a machine's condition through its lifespan. Thus, choosing the best sensor is a critical step to ensure the efficiency of the maintenance process. Indeed, considering the variety of sensors, and their features and performance, a formal classification of a sensor's domain knowledge is crucial. This classification facilitates the search for and reuse of solutions during the design of a new maintenance service. Following a Knowledge Management methodology, the paper proposes and develops a new sensor ontology that structures the domain knowledge, covering both theoretical and experimental sensor attributes. An industrial case study is conducted to validate the proposed ontology and to demonstrate its utility as a guideline to ease the search of suitable sensors. Based on the ontology, the final solution will be implemented in a shared repository connected to legacy CAD (computer-aided design) systems. The selection of the best sensor is, firstly, obtained by the matching of application requirements and sensor specifications (that are proposed by this sensor repository). Then, it is refined from the experimentation results. The achieved solution is recorded in the sensor repository for future reuse. As a result, the time and cost of the design process of new condition-based maintenance services is reduced.

  2. LightWAVE: Waveform and Annotation Viewing and Editing in a Web Browser.

    PubMed

    Moody, George B

    2013-09-01

    This paper describes LightWAVE, recently-developed open-source software for viewing ECGs and other physiologic waveforms and associated annotations (event markers). It supports efficient interactive creation and modification of annotations, capabilities that are essential for building new collections of physiologic signals and time series for research. LightWAVE is constructed of components that interact in simple ways, making it straightforward to enhance or replace any of them. The back end (server) is a common gateway interface (CGI) application written in C for speed and efficiency. It retrieves data from its data repository (PhysioNet's open-access PhysioBank archives by default, or any set of files or web pages structured as in PhysioBank) and delivers them in response to requests generated by the front end. The front end (client) is a web application written in JavaScript. It runs within any modern web browser and does not require installation on the user's computer, tablet, or phone. Finally, LightWAVE's scribe is a tiny CGI application written in Perl, which records the user's edits in annotation files. LightWAVE's data repository, back end, and front end can be located on the same computer or on separate computers. The data repository may be split across multiple computers. For compatibility with the standard browser security model, the front end and the scribe must be loaded from the same domain.

  3. The SKI repository performance assessment project Site-94

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Andersson, J.; Dverstorp, B.; Sjoeblom, R.

    1995-12-01

    SITE-94 is a research project conducted as a performance assessment of a hypothetical repository for spent nuclear fuel, but with real pre-excavation data from a real site. The geosphere, the engineered barriers and the processes for radionuclide release and transport comprise an integrated interdependent system, which is described by an influence diagram (PID) that reflects how different Features, Events or Processes (FEPs) inside the system interact. Site evaluation is used to determine information of transport paths in the geosphere and to deliver information on geosphere interaction with the engineered barriers. A three-dimensional geological structure model of the site as wellmore » as alternative conceptual models consistent with the existing hydrological field data, have been analyzed. Groundwater chemistry is evaluated and a model, fairly consistent with the flow model, for the origin of the different waters has been developed. The geological structure model is also used for analyzing the mechanical stability of the site. Several phenomena of relevance for copper corrosion in a repository environment have been investigated. For Reference Case conditions and regardless of flow variability, output is dominated by I-129, which, for a single canister, may give rise to drinking water well doses in the order of 10{sup -6}Sv/yr. Finally, it appears that the procedures involved in the development of influence diagrams may be a promising tool for quality assurance of performance assessments.« less

  4. Virtual patient repositories--a comparative analysis.

    PubMed

    Küfner, Julia; Kononowicz, Andrzej A; Hege, Inga

    2014-01-01

    Virtual Patients (VPs) are an important component of medical education. One way to reduce the costs for creating VPs is sharing through repositories. We conducted a literature review to identify existing repositories and analyzed the 17 included repositories in regards to the search functions and metadata they provide. Most repositories provided some metadata such as title or description, whereas other data, such as educational objectives, were less frequent. Future research could, in cooperation with the repository provider, investigate user expectations and usage patterns.

  5. Learning Object Repositories

    ERIC Educational Resources Information Center

    Lehman, Rosemary

    2007-01-01

    This chapter looks at the development and nature of learning objects, meta-tagging standards and taxonomies, learning object repositories, learning object repository characteristics, and types of learning object repositories, with type examples. (Contains 1 table.)

  6. Transportation plan repository and archive.

    DOT National Transportation Integrated Search

    2011-04-01

    This project created a repository and archive for transportation planning documents in Texas within the : established Texas A&M Repository (http://digital.library.tamu.edu). This transportation planning archive : and repository provides ready access ...

  7. Yucca blowup theory bombs, says study

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Taubes, G.

    The theory was explosive, but in its biggest test yet, it has fizzled. Last year, an unpublished paper circulated at the Los Alamos National Laboratory raised the possibility that the planned nuclear waste repository at Yucca Mountain, Nevada, might erupt in massive nuclear explosions. The scenario, which held that leaking waste could concentrate in the surrounding rock to form a {open_quotes}supercritical mass,{close_quotes} received heavy publicity. But a review released last week by the nuclear engineering department at the University of California, Berkeley, says it is not credible.

  8. Application Profiling for Rural Communities: eGov Services and Training Resources in Rural Inclusion

    NASA Astrophysics Data System (ADS)

    Karamolegkos, Pantelis; Maroudas, Axel; Manouselis, Nikos

    Metadata plays a critical role in the design and development of online repositories. The efficiency and ease of use of the repositories are directly associated with the metadata structure, since end-user functionalities such as search, retrieval and access are highly dependent on how the metadata schema and application profile have been conceptualized and implemented. The need for efficient and interoperable application profiles is even more substantial when it comes to services related to the e-government (eGov) paradigm, given a) the close association between services related to eGov and the metadata usage and b) the fact that the eGov concept is associated with time and cost critical processes, i.e. interaction of citizens and services with public authorities. In this paper, we outline an effort related to application profiling for eGov services and training resources, used in the platform of RuralObservatory2.0, which will underpin a major objective of the ICT PSP Rural Inclusion project, i.e. the eGov paradigm uptake by rural communities.

  9. Introduction to the hydrogeochemical investigations within the International Stripa Project

    USGS Publications Warehouse

    Nordstrom, D. Kirk; Olsson, T.; Carlsson, L.; Fritz, P.

    1989-01-01

    The International Stripa Project (1980-1990) has sponsored hydrogeochemical investigations at several subsurface drillholes in the granitic portion of an abandoned iron ore mine, central Sweden. The purpose has been to advance our understanding of geochemical processes in crystalline bedrock that may affect the safety assessment of high-level radioactive waste repositories. More than a dozen investigators have collected close to a thousand water and gas samples for chemical and isotopic analyses to develop concepts for the behavior of solutes in a granitic repository environment. The Stripa granite is highly radioactive and has provided an exceptional opportunity to study the behavior of natural radionuclides, especially subsurface production. Extensive microfracturing, low permeability with isolated fracture zones of high permeability, unusual water chemistry, and a typical granitic mineral assemblage with thin veins and fracture coatings of calcite, chlorite, seriate, epidote and quartz characterize the site. Preliminary groundwater flow modeling indicates that the mine has perturbed the flow environment to a depth of about 3 km and may have induced deep groundwaters to flow into the mine. ?? 1989.

  10. Rolling Deck to Repository (R2R): Standards and Semantics for Open Access to Research Data

    NASA Astrophysics Data System (ADS)

    Arko, Robert; Carbotte, Suzanne; Chandler, Cynthia; Smith, Shawn; Stocks, Karen

    2015-04-01

    In recent years, a growing number of funding agencies and professional societies have issued policies calling for open access to research data. The Rolling Deck to Repository (R2R) program is working to ensure open access to the environmental sensor data routinely acquired by the U.S. academic research fleet. Currently 25 vessels deliver 7 terabytes of data to R2R each year, acquired from a suite of geophysical, oceanographic, meteorological, and navigational sensors on over 400 cruises worldwide. R2R is working to ensure these data are preserved in trusted repositories, discoverable via standard protocols, and adequately documented for reuse. R2R maintains a master catalog of cruises for the U.S. academic research fleet, currently holding essential documentation for over 3,800 expeditions including vessel and cruise identifiers, start/end dates and ports, project titles and funding awards, science parties, dataset inventories with instrument types and file formats, data quality assessments, and links to related content at other repositories. A Digital Object Identifier (DOI) is published for 1) each cruise, 2) each original field sensor dataset, 3) each post-field data product such as quality-controlled shiptrack navigation produced by the R2R program, and 4) each document such as a cruise report submitted by the science party. Scientists are linked to personal identifiers, such as the Open Researcher and Contributor ID (ORCID), where known. Using standard global identifiers such as DOIs and ORCIDs facilitates linking with journal publications and generation of citation metrics. Since its inception, the R2R program has worked in close collaboration with other data repositories in the development of shared semantics for oceanographic research. The R2R cruise catalog uses community-standard terms and definitions hosted by the NERC Vocabulary Server, and publishes ISO metadata records for each cruise that use community-standard profiles developed with the NOAA Data Centers and the EU SeaDataNet project. R2R is a partner in the Ocean Data Interoperability Platform (ODIP), working to strengthen links among regional and national data systems, as well as a lead partner in the EarthCube "GeoLink" project, developing a standard set of ontology design patterns for publishing research data using Semantic Web protocols.

  11. Supporting multiple domains in a single reuse repository

    NASA Technical Reports Server (NTRS)

    Eichmann, David A.

    1992-01-01

    Domain analysis typically results in the construction of a domain-specific repository. Such a repository imposes artificial boundaries on the sharing of similar assets between related domains. A lattice-based approach to repository modeling can preserve a reuser's domain specific view of the repository, while avoiding replication of commonly used assets and supporting a more general perspective on domain interrelationships.

  12. NCI Mouse Repository | FNLCR Staging

    Cancer.gov

    The NCI Mouse Repository is an NCI-funded resource for mouse cancer models and associated strains. The repository makes strains available to all members of the scientific community (academic, non-profit, and commercial). NCI Mouse Repository strains

  13. The Pediatric Imaging, Neurocognition, and Genetics (PING) Data Repository

    PubMed Central

    Jernigan, Terry L.; Brown, Timothy T.; Hagler, Donald J.; Akshoomoff, Natacha; Bartsch, Hauke; Newman, Erik; Thompson, Wesley K.; Bloss, Cinnamon S.; Murray, Sarah S.; Schork, Nicholas; Kennedy, David N.; Kuperman, Joshua M.; McCabe, Connor; Chung, Yoonho; Libiger, Ondrej; Maddox, Melanie; Casey, B. J.; Chang, Linda; Ernst, Thomas M.; Frazier, Jean A.; Gruen, Jeffrey R.; Sowell, Elizabeth R.; Kenet, Tal; Kaufmann, Walter E.; Mostofsky, Stewart; Amaral, David G.; Dale, Anders M.

    2015-01-01

    The main objective of the multi-site Pediatric Imaging, Neurocognition, and Genetics (PING) study was to create a large repository of standardized measurements of behavioral and imaging phenotypes accompanied by whole genome genotyping acquired from typically-developing children varying widely in age (3 to 20 years). This cross-sectional study produced sharable data from 1493 children, and these data have been described in several publications focusing on brain and cognitive development. Researchers may gain access to these data by applying for an account on the PING Portal and filing a Data Use Agreement. Here we describe the recruiting and screening of the children and give a brief overview of the assessments performed, the imaging methods applied, the genetic data produced, and the numbers of cases for whom different data types are available. We also cite sources of more detailed information about the methods and data. Finally we describe the procedures for accessing the data and for using the PING data exploration portal. PMID:25937488

  14. The Pediatric Imaging, Neurocognition, and Genetics (PING) Data Repository.

    PubMed

    Jernigan, Terry L; Brown, Timothy T; Hagler, Donald J; Akshoomoff, Natacha; Bartsch, Hauke; Newman, Erik; Thompson, Wesley K; Bloss, Cinnamon S; Murray, Sarah S; Schork, Nicholas; Kennedy, David N; Kuperman, Joshua M; McCabe, Connor; Chung, Yoonho; Libiger, Ondrej; Maddox, Melanie; Casey, B J; Chang, Linda; Ernst, Thomas M; Frazier, Jean A; Gruen, Jeffrey R; Sowell, Elizabeth R; Kenet, Tal; Kaufmann, Walter E; Mostofsky, Stewart; Amaral, David G; Dale, Anders M

    2016-01-01

    The main objective of the multi-site Pediatric Imaging, Neurocognition, and Genetics (PING) study was to create a large repository of standardized measurements of behavioral and imaging phenotypes accompanied by whole genome genotyping acquired from typically-developing children varying widely in age (3 to 20 years). This cross-sectional study produced sharable data from 1493 children, and these data have been described in several publications focusing on brain and cognitive development. Researchers may gain access to these data by applying for an account on the PING portal and filing a data use agreement. Here we describe the recruiting and screening of the children and give a brief overview of the assessments performed, the imaging methods applied, the genetic data produced, and the numbers of cases for whom different data types are available. We also cite sources of more detailed information about the methods and data. Finally we describe the procedures for accessing the data and for using the PING data exploration portal. Copyright © 2015 Elsevier Inc. All rights reserved.

  15. Integration of Multi-Modal Biomedical Data to Predict Cancer Grade and Patient Survival.

    PubMed

    Phan, John H; Hoffman, Ryan; Kothari, Sonal; Wu, Po-Yen; Wang, May D

    2016-02-01

    The Big Data era in Biomedical research has resulted in large-cohort data repositories such as The Cancer Genome Atlas (TCGA). These repositories routinely contain hundreds of matched patient samples for genomic, proteomic, imaging, and clinical data modalities, enabling holistic and multi-modal integrative analysis of human disease. Using TCGA renal and ovarian cancer data, we conducted a novel investigation of multi-modal data integration by combining histopathological image and RNA-seq data. We compared the performances of two integrative prediction methods: majority vote and stacked generalization. Results indicate that integration of multiple data modalities improves prediction of cancer grade and outcome. Specifically, stacked generalization, a method that integrates multiple data modalities to produce a single prediction result, outperforms both single-data-modality prediction and majority vote. Moreover, stacked generalization reveals the contribution of each data modality (and specific features within each data modality) to the final prediction result and may provide biological insights to explain prediction performance.

  16. Resolving Past Liabilities for Future Reduction in Greenhouse Gases; Nuclear Energy and the Outstanding Federal Liability of Spent Nuclear Fuel

    NASA Astrophysics Data System (ADS)

    Donohue, Jay

    This thesis will: (1) examine the current state of nuclear power in the U.S.; (2) provide a comparison of nuclear power to both existing alternative/renewable sources of energy as well as fossil fuels; (3) dissect Standard Contracts created pursuant to the National Waste Policy Act (NWPA), Congress' attempt to find a solution for Spent Nuclear Fuel (SNF), and the designation of Yucca Mountain as a repository; (4) the anticipated failure of Yucca Mountain; (5) explore WIPP as well as attempts to build a facility on Native American land in Utah; (6) examine reprocessing as a solution for SNF used by France and Japan; and, finally, (7) propose a solution to reduce GHG's by developing new nuclear energy plants with financial support from the U.S. government and a solution to build a storage facility for SNF through the sitting of a repository based on a "bottom-up" cooperative federalism approach.

  17. Minimization of extracellular space as a driving force in prokaryote association and the origin of eukaryotes.

    PubMed

    Hooper, Scott L; Burstein, Helaine J

    2014-11-18

    Internalization-based hypotheses of eukaryotic origin require close physical association of host and symbiont. Prior hypotheses of how these associations arose include chance, specific metabolic couplings between partners, and prey-predator/parasite interactions. Since these hypotheses were proposed, it has become apparent that mixed-species, close-association assemblages (biofilms) are widespread and predominant components of prokaryotic ecology. Which forces drove prokaryotes to evolve the ability to form these assemblages are uncertain. Bacteria and archaea have also been found to form membrane-lined interconnections (nanotubes) through which proteins and RNA pass. These observations, combined with the structure of the nuclear envelope and an energetic benefit of close association (see below), lead us to propose a novel hypothesis of the driving force underlying prokaryotic close association and the origin of eukaryotes. Respiratory proton transport does not alter external pH when external volume is effectively infinite. Close physical association decreases external volume. For small external volumes, proton transport decreases external pH, resulting in each transported proton increasing proton motor force to a greater extent. We calculate here that in biofilms this effect could substantially decrease how many protons need to be transported to achieve a given proton motor force. Based as it is solely on geometry, this energetic benefit would occur for all prokaryotes using proton-based respiration. This benefit may be a driving force in biofilm formation. Under this hypothesis a very wide range of prokaryotic species combinations could serve as eukaryotic progenitors. We use this observation and the discovery of prokaryotic nanotubes to propose that eukaryotes arose from physically distinct, functionally specialized (energy factory, protein factory, DNA repository/RNA factory), obligatorily symbiotic prokaryotes in which the protein factory and DNA repository/RNA factory cells were coupled by nanotubes and the protein factory ultimately internalized the other two. This hypothesis naturally explains many aspects of eukaryotic physiology, including the nuclear envelope being a folded single membrane repeatedly pierced by membrane-bound tubules (the nuclear pores), suggests that species analogous or homologous to eukaryotic progenitors are likely unculturable as monocultures, and makes a large number of testable predictions. This article was reviewed by Purificación López-García and Toni Gabaldón.

  18. PSU/WES Interlaboratory Comparative Methodology Study of an Experimental Cementitious Repository Seal Material. Report 2. Final Results.

    DTIC Science & Technology

    1982-03-01

    meter 25 11.0 Microstructure by SEM 11.1 Introduction In order to correlate observed physical and mechanical properties in cured grout samples, a...studied at the two laboratories has proper physical properties , phase composi- tions, and microstructures for the materials used and ages covered...Scanning Electron Microscope Resolution Test Specimen ( Al -W) D. B. Ballard Research Material 100 SEM Resolution Test Specimen (AI-W)., is an alloy of

  19. High-Level Waste System Process Interface Description

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    d'Entremont, P.D.

    1999-01-14

    The High-Level Waste System is a set of six different processes interconnected by pipelines. These processes function as one large treatment plant that receives, stores, and treats high-level wastes from various generators at SRS and converts them into forms suitable for final disposal. The three major forms are borosilicate glass, which will be eventually disposed of in a Federal Repository, Saltstone to be buried on site, and treated water effluent that is released to the environment.

  20. Bentonite Clay Evolution at Elevated Pressures and Temperatures: An experimental study for generic nuclear repositories

    NASA Astrophysics Data System (ADS)

    Caporuscio, F. A.; Cheshire, M.; McCarney, M.

    2012-12-01

    The Used Fuel Disposition Campaign is presently engaged in looking at various generic repository options for disposal of used fuel. Of interest are the disposal of high heat load canisters ,which may allow for a reduced repository footprint. The focus of this experimental work is to characterize Engineered Barrier Systems (EBS) conditions in repositories. Clay minerals - as backfill or buffer materials - are critical to the performance of the EBS. Experiments were performed in Dickson cells at 150 bar and sequentially stepped from 125 oC to 300 oC over a period of ~1 month. An unprocessed bentonite from Colony, Wyoming was used as the buffer material in each experiment. An K-Ca-Na-Cl-rich brine (replicating deep Stripa groundwater) was used at a 9:1 water:rock ratio. The baseline experiment contained brine + clay, while three other experiments contained metals that could be used as waste form canisters (brine +clay+304SS, brine+clay+316SS, brine+clay+Cu). All experiments were buffered at the Mt-Fe oxygen fugacity univarient line. As experiment temperature increased and time progressed, pH, K and Ca ion concentrations dropped, while Si, Na, and SO4 concentrations increased. Silicon was liberated into the fluid phase (>1000 ppm) and precipitated during the quenching of the experiment. The precipitated silica transformed to cristobalite as cooling progressed. Potassium was mobilized and exchanged with interlayer Na, transitioning the clay from Na-montmorillonite to K-smectite. Though illitization was not observed in these experiments, its formation may be kinetically limited and longer-term experiments are underway to evaluate the equilibrium point in this reaction. Clinoptilolite present in the starting bentonite mixture is unstable above 150 oC. Hence, the zeolite broke down at high temperatures but recrystallized as the quench event occurred. This was borne out in SEM images that showed clinoptilolite as a very late stage growth mineral. Both experimental runs containing steel exhibit the generation of a chlorite / Fe-saponite layer at the clay-metal boundary. The formation of minor amounts of pentlandite [(Fe,Ni)9S8] also occurs on both steel plates. Chalcocite (Cu2S) formed as a corrosion product on the Cu plates. The two sulfide phases have been produced by the generation of H2S gas during the experimental runs. The H2S is formed by the breakdown of pyrite framboids at high temperature in the bentonite. Such experiments on representative EBS materials at elevated P,T repository conditions are providing useful information for generic repository studies. Lack of illite formation is common in clay experiments and may be related to kinetics or K concentration. Precipitated SiO2 may potentially seal heating cracks in the clay backfill. The chlorite layer generated on steel may act as a passivation material and prevent corrosion of the steel canister wall. Finally, even if zeolites break down during the high temperature thermal pulse of a repository, zeolites may form again as the repository inventory cools off and perform as radionuclide sorbing phases.

  1. Coupling fuel cycles with repositories: how repository institutional choices may impact fuel cycle design

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Forsberg, C.; Miller, W.F.

    2013-07-01

    The historical repository siting strategy in the United States has been a top-down approach driven by federal government decision making but it has been a failure. This policy has led to dispatching fuel cycle facilities in different states. The U.S. government is now considering an alternative repository siting strategy based on voluntary agreements with state governments. If that occurs, state governments become key decision makers. They have different priorities. Those priorities may change the characteristics of the repository and the fuel cycle. State government priorities, when considering hosting a repository, are safety, financial incentives and jobs. It follows that statesmore » will demand that a repository be the center of the back end of the fuel cycle as a condition of hosting it. For example, states will push for collocation of transportation services, safeguards training, and navy/private SNF (Spent Nuclear Fuel) inspection at the repository site. Such activities would more than double local employment relative to what was planned for the Yucca Mountain-type repository. States may demand (1) the right to take future title of the SNF so if recycle became economic the reprocessing plant would be built at the repository site and (2) the right of a certain fraction of the repository capacity for foreign SNF. That would open the future option of leasing of fuel to foreign utilities with disposal of the SNF in the repository but with the state-government condition that the front-end fuel-cycle enrichment and fuel fabrication facilities be located in that state.« less

  2. NCI Mouse Repository | Frederick National Laboratory for Cancer Research

    Cancer.gov

    The NCI Mouse Repository is an NCI-funded resource for mouse cancer models and associated strains. The repository makes strains available to all members of the scientific community (academic, non-profit, and commercial). NCI Mouse Repository strains

  3. 48 CFR 227.7207 - Contractor data repositories.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... repositories. 227.7207 Section 227.7207 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS... Computer Software and Computer Software Documentation 227.7207 Contractor data repositories. Follow 227.7108 when it is in the Government's interests to have a data repository include computer software or to...

  4. 75 FR 70310 - Sunshine Act Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-17

    ... Consumer Protection Act governing the security-based swap data repository registration process, the duties of such repositories, and the core principles applicable to such repositories. 4. The Commission will... security-based swap data repositories or the Commission and the public dissemination of security-based swap...

  5. EarthCube GeoLink: Semantics and Linked Data for the Geosciences

    NASA Astrophysics Data System (ADS)

    Arko, R. A.; Carbotte, S. M.; Chandler, C. L.; Cheatham, M.; Fils, D.; Hitzler, P.; Janowicz, K.; Ji, P.; Jones, M. B.; Krisnadhi, A.; Lehnert, K. A.; Mickle, A.; Narock, T.; O'Brien, M.; Raymond, L. M.; Schildhauer, M.; Shepherd, A.; Wiebe, P. H.

    2015-12-01

    The NSF EarthCube initiative is building next-generation cyberinfrastructure to aid geoscientists in collecting, accessing, analyzing, sharing, and visualizing their data and knowledge. The EarthCube GeoLink Building Block project focuses on a specific set of software protocols and vocabularies, often characterized as the Semantic Web and "Linked Data", to publish data online in a way that is easily discoverable, accessible, and interoperable. GeoLink brings together specialists from the computer science, geoscience, and library science domains, and includes data from a network of NSF-funded repositories that support scientific studies in marine geology, marine ecosystems, biogeochemistry, and paleoclimatology. We are working collaboratively with closely-related Building Block projects including EarthCollab and CINERGI, and solicit feedback from RCN projects including Cyberinfrastructure for Paleogeosciences (C4P) and iSamples. GeoLink has developed a modular ontology that describes essential geoscience research concepts; published data from seven collections (to date) on the Web as geospatially-enabled Linked Data using this ontology; matched and mapped data between collections using shared identifiers for investigators, repositories, datasets, funding awards, platforms, research cruises, physical specimens, and gazetteer features; and aggregated the results in a shared knowledgebase that can be queried via a standard SPARQL endpoint. Client applications have been built around the knowledgebase, including a Web/map-based data browser using the Leaflet JavaScript library and a simple query service using the OpenSearch format. Future development will include extending and refining the GeoLink ontology, adding content from additional repositories, developing semi-automated algorithms to enhance metadata, and further work on client applications.

  6. The New Face of Data Accessibility

    NASA Technical Reports Server (NTRS)

    Fitts, Mary A.; VanBaalan, Mary; Johnson-Throop, Kathy A.; Thomas, Deidre; Havelka, Jacque

    2010-01-01

    Management of medical and research data at NASA's Johnson Space Center has been addressed with two separate, independent systems: the Lifetime Surveillance of Astronaut Health (formerly, The Longitudinal Study of Astronaut Health) (LSAH) and the Life Sciences Data Archive (LSDA). Project management for these has been autonomous with little or no cross-over of goals, objectives or strategy. The result has been limited debate and discussion regarding how contents from one repository might impact or guide the direction of the other. It is decidedly more efficient to use existing data and information than to re-generate them. Ensuring that both clinical and research data / information are accessible for review is a central concept to the decision to unify these repositories. In the past, research data from flight and ground analogs has been held in the LSDA and medical data held in the Electronic Medical Record or in console flight surgeon logs and records. There was little cross-pollination between medical and research findings and, as a result, applicable research was not being fully incorporated into clinical, in-flight practice. Conversely, findings by the console surgeon were not being picked up by the research community. The desired life cycle for risk mitigation was not being fully realized. The goal of unifying these repositories and processes is to provide a closely knit approach to handling medical and research data, which will not only engender discussion and debate but will also ensure that both categories of data and information are used to enhance the use of medical and research data to reduce risk and promote the understanding of space physiology, countermeasures and other mitigation strategies

  7. Core Certification of Data Repositories: Trustworthiness and Long-Term Stewardship

    NASA Astrophysics Data System (ADS)

    de Sherbinin, A. M.; Mokrane, M.; Hugo, W.; Sorvari, S.; Harrison, S.

    2017-12-01

    Scientific integrity and norms dictate that data created and used by scientists should be managed, curated, and archived in trustworthy data repositories thus ensuring that science is verifiable and reproducible while preserving the initial investment in collecting data. Research stakeholders including researchers, science funders, librarians, and publishers must also be able to establish the trustworthiness of data repositories they use to confirm that the data they submit and use remain useful and meaningful in the long term. Data repositories are increasingly recognized as a key element of the global research infrastructure and the importance of establishing their trustworthiness is recognised as a prerequisite for efficient scientific research and data sharing. The Core Trustworthy Data Repository Requirements are a set of universal requirements for certification of data repositories at the core level (see: https://goo.gl/PYsygW). They were developed by the ICSU World Data System (WDS: www.icsu-wds.org) and the Data Seal of Approval (DSA: www.datasealofapproval.org)—the two authoritative organizations responsible for the development and implementation of this standard to be further developed under the CoreTrustSeal branding . CoreTrustSeal certification of data repositories involves a minimally intensive process whereby repositories supply evidence that they are sustainable and trustworthy. Repositories conduct a self-assessment which is then reviewed by community peers. Based on this review CoreTrustSeal certification is granted by the CoreTrustSeal Standards and Certification Board. Certification helps data communities—producers, repositories, and consumers—to improve the quality and transparency of their processes, and to increase awareness of and compliance with established standards. This presentation will introduce the CoreTrustSeal certification requirements for repositories and offer an opportunity to discuss ways to improve the contribution of certified data repositories to sustain open data for open scientific research.

  8. Future ice ages and the challenges related to final disposal of nuclear waste: The Greenland Ice Sheet Hydrology Project

    NASA Astrophysics Data System (ADS)

    Lehtinen, A.; Claesson-Liljedahl, L.; Näslund, J.-O.; Ruskeeniemi, T.

    2009-04-01

    A deep geological repository for nuclear waste is designed to keep radiotoxic material separated from mankind and the environment for several hundreds of thousands of years. Within this time perspective glacial conditions are expected in high latitudes/Canada and North Europe. Climate induced changes such as the growth of ice sheets and permafrost will influence and alter the ground surface and subsurface environment, which may impact repository safety. In order to understand how climate change, particularly cooling and glaciation, might affect a repository in the long term, the use of present-day analogues helps to reduce the uncertainties and support the assumptions made in safety assessments. There are major uncertainties concerning hydrological processes related to glacial conditions. The impact of glaciations on any planned repository is a key consideration when performing safety assessments as it is one of the strongest perturbations related to climate change in the long term. The main aspects that need to be further investigated include: 1) to what extent does the meltwater produced by an ice sheet penetrates into the bedrock; 2) what is the pressure situation under an ice sheet, driving ground water flow; 3) how much oxygenated water will reach repository depth; 4) to what depth does glacial meltwater penetrate into the bedrock ; 5)what chemical composition does such water has when and if it reaches repository depth; and 6) can taliks (unfrozen ground in a permafrost area) act as concentrated discharge points of deep groundwater potentially transporting radionuclides in case of repository failure? Field data is needed in order to achieve a better and integrated understanding of the problems discussed above. Thus, research in a natural analogue site in Greenland has been planned and initiated by the Finnish (Posiva), Swedish (SKB) and Canadian (NWMO) nuclear waste management companies. The Greenland ice sheet and the Kangerlussuaq area (west Greenland) provides a good analogue for this purpose due to similarities in geology (in the selected study area), and the climate conditions and ice sheet size in Kangerlussuaq resemble the expected conditions in Fennoscandia during future glaciations. In 2005 and 2008 reconnaissance field trips were made to Kangerlussuaq, which confirmed the suitability of the area for the planned studies. According to the present Work Programme the investigations will be carried out in 2009-2012. The project is divided into four subprojects (SPA, SPB, SPC and SPD) addressing specific and different topics at or in relation to the ice margin: SPA (ice sheet hydrology and glacial groundwater formation); SPB (subglacial ice sheet hydrology), SPC (hydrogeochemistry and hydrogeology) and SPD (periglacial environment: biosphere and permafrost). The main objectives of SPA and SPB are to gain a better process understanding of supra- and subglacial hydrology. Qualitative and quantitative knowledge of the mechanisms, rates and distribution of the melt water recharge through the ice down to the bed, location and extension of warm-based areas and hydraulic pressure conditions at the base are the key issues to be studied. This will be made by meteorological observations, GPS measurements, radar surveys, drilling through the ice sheet and by ice sheet modelling. SPC will further study the fate of melt water by extending the investigations into the bedrock. It is assumed that the high hydraulic pressures at the ice sheet bed force water into the fracture network prevailing in the bedrock. However, it is not known how the fracture network behaves under loading, what is the proportion of recharging water compared to the drainage through the bed sediments, what is the intrusion depth, how long the meltwater can sustain its oxic nature and what chemical composition the recharging water has when and if it reaches repository depth (400-700 m). SPC seeks to answer these questions by drilling and instrumenting boreholes drilled into the bedrock and below the ice sheet. SPD is aiming at describing and studying processes acting in the periglacial environment affected by permafrost conditions. The observations will be used within the safety assessment biosphere programs. From the acquired results we will obtain data, which will allow us to develop better conceptual and numerical models for quantitative analysis of ice sheet hydrology and dynamics, groundwater flow, groundwater chemistry and hydro-mechanical couplings during glacial periods, by reducing uncertainties and better constraining the boundary conditions used in the models. Finally, this project concerns the first in situ investigation of the vital parameters needed to achieve a holistic and realistic understanding of how an ice sheet may impact a deep geological repository for spent nuclear waste and will provide the necessary integrated view of ice sheet hydrology and groundwater flow/chemistry needed when executing safety assessments for the geological repositories in Sweden, Finland and Canada.

  9. The preliminary design and feasibility study of the spent fuel and high level waste repository in the Czech Republic

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Valvoda, Z.; Holub, J.; Kucerka, M.

    1996-12-31

    In the year 1993, began the Program of Development of the Spent Fuel and High Level Waste Repository in the Conditions of the Czech Republic. During the first phase, the basic concept and structure of the Program has been developed, and the basic design criteria and requirements were prepared. In the conditions of the Czech Republic, only an underground repository in deep geological formation is acceptable. Expected depth is between 500 to 1000 meters and as host rock will be granites. A preliminary variant design study was realized in 1994, that analyzed the radioactive waste and spent fuel flow frommore » NPPs to the repository, various possibilities of transportation in accordance to the various concepts of spent fuel conditioning and transportation to the underground structures. Conditioning and encapsulation of spent fuel and/or radioactive waste is proposed on the repository site. Underground disposal structures are proposed at one underground floor. The repository will have reserve capacity for radioactive waste from NPPs decommissioning and for waste non acceptable to other repositories. Vertical disposal of unshielded canisters in boreholes and/or horizontal disposal of shielded canisters is studied. As the base term of the start up of the repository operation, the year 2035 has been established. From this date, a preliminary time schedule of the Project has been developed. A method of calculating leveled and discounted costs within the repository lifetime, for each of selected 5 variants, was used for economic calculations. Preliminary expected parametric costs of the repository are about 0,1 Kc ($0.004) per MWh, produced in the Czech NPPs. In 1995, the design and feasibility study has gone in more details to the technical concept of repository construction and proposed technologies, as well as to the operational phase of the repository. Paper will describe results of the 1995 design work and will present the program of the repository development in next period.« less

  10. 17 CFR 49.26 - Disclosure requirements of swap data repositories.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... data repository's policies and procedures reasonably designed to protect the privacy of any and all... swap data repositories. 49.26 Section 49.26 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION (CONTINUED) SWAP DATA REPOSITORIES § 49.26 Disclosure requirements of swap data...

  11. Implementing the EuroFIR Document and Data Repositories as accessible resources of food composition information.

    PubMed

    Unwin, Ian; Jansen-van der Vliet, Martine; Westenbrink, Susanne; Presser, Karl; Infanger, Esther; Porubska, Janka; Roe, Mark; Finglas, Paul

    2016-02-15

    The EuroFIR Document and Data Repositories are being developed as accessible collections of source documents, including grey literature, and the food composition data reported in them. These Repositories will contain source information available to food composition database compilers when selecting their nutritional data. The Document Repository was implemented as searchable bibliographic records in the Europe PubMed Central database, which links to the documents online. The Data Repository will contain original data from source documents in the Document Repository. Testing confirmed the FoodCASE food database management system as a suitable tool for the input, documentation and quality assessment of Data Repository information. Data management requirements for the input and documentation of reported analytical results were established, including record identification and method documentation specifications. Document access and data preparation using the Repositories will provide information resources for compilers, eliminating duplicated work and supporting unambiguous referencing of data contributing to their compiled data. Copyright © 2014 Elsevier Ltd. All rights reserved.

  12. Making research data repositories visible: the re3data.org Registry.

    PubMed

    Pampel, Heinz; Vierkant, Paul; Scholze, Frank; Bertelmann, Roland; Kindling, Maxi; Klump, Jens; Goebelbecker, Hans-Jürgen; Gundlach, Jens; Schirmbacher, Peter; Dierolf, Uwe

    2013-01-01

    Researchers require infrastructures that ensure a maximum of accessibility, stability and reliability to facilitate working with and sharing of research data. Such infrastructures are being increasingly summarized under the term Research Data Repositories (RDR). The project re3data.org-Registry of Research Data Repositories-has begun to index research data repositories in 2012 and offers researchers, funding organizations, libraries and publishers an overview of the heterogeneous research data repository landscape. In July 2013 re3data.org lists 400 research data repositories and counting. 288 of these are described in detail using the re3data.org vocabulary. Information icons help researchers to easily identify an adequate repository for the storage and reuse of their data. This article describes the heterogeneous RDR landscape and presents a typology of institutional, disciplinary, multidisciplinary and project-specific RDR. Further the article outlines the features of re3data.org, and shows how this registry helps to identify appropriate repositories for storage and search of research data.

  13. 17 CFR 49.19 - Core principles applicable to registered swap data repositories.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... registered swap data repositories. 49.19 Section 49.19 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION (CONTINUED) SWAP DATA REPOSITORIES § 49.19 Core principles applicable to registered swap data repositories. (a) Compliance with core principles. To be registered, and maintain...

  14. 17 CFR 49.26 - Disclosure requirements of swap data repositories.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... TRADING COMMISSION SWAP DATA REPOSITORIES § 49.26 Disclosure requirements of swap data repositories... swap data repository shall furnish to the reporting entity a disclosure document that contains the... 17 Commodity and Securities Exchanges 1 2013-04-01 2013-04-01 false Disclosure requirements of...

  15. 17 CFR 49.26 - Disclosure requirements of swap data repositories.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... TRADING COMMISSION SWAP DATA REPOSITORIES § 49.26 Disclosure requirements of swap data repositories... swap data repository shall furnish to the reporting entity a disclosure document that contains the... 17 Commodity and Securities Exchanges 1 2012-04-01 2012-04-01 false Disclosure requirements of...

  16. 21 CFR 522.480 - Repository corticotropin injection.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Repository corticotropin injection. 522.480 Section 522.480 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES... § 522.480 Repository corticotropin injection. (a)(1) Specifications. The drug conforms to repository...

  17. 10 CFR 960.3-1-3 - Regionality.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... REPOSITORY Implementation Guidelines § 960.3-1-3 Regionality. In making site recommendations for repository development after the site for the first repository has been recommended, the Secretary shall give due... repositories. Such consideration shall take into account the proximity of sites to locations at which waste is...

  18. Environmental assessment: Davis Canyon site, Utah

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    none,

    1986-05-01

    In February 1983, the US Department of Energy (DOE) identified the Davis Canyon site in Utah as one of the nine potentially acceptable sites for a mined geologic repository for spent nuclear fuel and high-level radioactive waste. To determine their suitability, the Davis Canyon site and the eight other potentially acceptable sites have been evaluated in accordance with the DOE's General Guidelines for the Recommendation of Sites for the Nuclear Waste Repositories. These evaluations were reported in draft environmental assessments (EAs), which were issued for public review and comment. After considering the comments received on the draft EAs, the DOEmore » prepared the final EA. The Davis Canyon site is in the Paradox Basin, which is one of five distinct geohydrologic settings considering for the first repository. This setting contains one other potentially acceptable site -- the Lavender Canyon site. Although the Lavender Canyon site is suitable for site characterization, the DOE has concluded that the Davis Canyon site is the preferred site in the Paradox Basin. On the basis of the evaluations reported in this EA, the DOE has found that the Davis Canyon site is not disqualified under the guidelines. Furthermore, the DOE has found that the site is suitable for site characterization because the evidence does not support a conclusion that the site will not be able to meet each of the qualifying conditions specified in the guidelines. On the basis of these findings, the DOE is nominating the Davis Canyon site as one of five sites suitable for characterization.« less

  19. A Tailored Ontology Supporting Sensor Implementation for the Maintenance of Industrial Machines

    PubMed Central

    Belkadi, Farouk; Bernard, Alain

    2017-01-01

    The longtime productivity of an industrial machine is improved by condition-based maintenance strategies. To do this, the integration of sensors and other cyber-physical devices is necessary in order to capture and analyze a machine’s condition through its lifespan. Thus, choosing the best sensor is a critical step to ensure the efficiency of the maintenance process. Indeed, considering the variety of sensors, and their features and performance, a formal classification of a sensor’s domain knowledge is crucial. This classification facilitates the search for and reuse of solutions during the design of a new maintenance service. Following a Knowledge Management methodology, the paper proposes and develops a new sensor ontology that structures the domain knowledge, covering both theoretical and experimental sensor attributes. An industrial case study is conducted to validate the proposed ontology and to demonstrate its utility as a guideline to ease the search of suitable sensors. Based on the ontology, the final solution will be implemented in a shared repository connected to legacy CAD (computer-aided design) systems. The selection of the best sensor is, firstly, obtained by the matching of application requirements and sensor specifications (that are proposed by this sensor repository). Then, it is refined from the experimentation results. The achieved solution is recorded in the sensor repository for future reuse. As a result, the time and cost of the design process of new condition-based maintenance services is reduced. PMID:28885592

  20. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Xiong, Yongliang

    In this study, solubility constants of hydroxyl sodalite (ideal formula, Na 8[Al 6Si 6O 24][OH] 2·3H 2O) from 25°C to 100°C are obtained by applying a high temperature Al—Si Pitzer model to evaluate solubility data on hydroxyl sodalite in high ionic strength solutions at elevated temperatures. A validation test comparing model-independent experimental data to model predictions demonstrates that the solubility values produced by the model are in excellent agreement with the experimental data. In addition, the equilibrium constants obtained in this study have a wide range of applications, including synthesis of hydroxyl sodalite, de-silication in the Bayer process for extractionmore » of alumina, and the performance of proposed sodalite waste forms in geological repositories in various lithologies including salt formations. The thermodynamic calculations based on the equilibrium constants obtained in this work indicate that the solubility products in terms of m ΣAl×m ΣSi for hydroxyl sodalite are very low (e.g., ~10 -13 [mol·kg -1] 2 at 100°C) in brines characteristic of salt formations, implying that sodalite waste forms would perform very well in repositories located in salt formations. Finally, the information regarding the solubility behavior of hydroxyl sodalite obtained in this study provides guidance to investigate the performance of other pure end-members of sodalite such as chloride- and iodide-sodalite, which may be of interest for geological repositories in various media.« less

  1. 17 CFR 49.19 - Core principles applicable to registered swap data repositories.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... registered swap data repositories. 49.19 Section 49.19 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION SWAP DATA REPOSITORIES § 49.19 Core principles applicable to registered swap data repositories. (a) Compliance with core principles. To be registered, and maintain registration, a swap data...

  2. 17 CFR 49.19 - Core principles applicable to registered swap data repositories.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... registered swap data repositories. 49.19 Section 49.19 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION SWAP DATA REPOSITORIES § 49.19 Core principles applicable to registered swap data repositories. (a) Compliance with Core Principles. To be registered, and maintain registration, a swap data...

  3. 17 CFR 49.22 - Chief compliance officer.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... that the registered swap data repository provide fair and open access as set forth in § 49.27 of this...) SWAP DATA REPOSITORIES § 49.22 Chief compliance officer. (a) Definition of Board of Directors. For... data repository, or for those swap data repositories whose organizational structure does not include a...

  4. 75 FR 8701 - Notice of Settlement Agreement Pertaining to Construction of a Waste Repository on the Settlors...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-25

    ... Construction of a Waste Repository on the Settlors' Property Pursuant to the Comprehensive Environmental... a Settlement Agreement pertaining to Construction of a Waste Repository on Settlor's Property... waste repository on the property by resolving, liability the settling party might otherwise incur under...

  5. 10 CFR 51.67 - Environmental information concerning geologic repositories.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Environmental information concerning geologic repositories... information concerning geologic repositories. (a) In lieu of an environmental report, the Department of Energy... connection with any geologic repository developed under Subtitle A of Title I, or under Title IV, of the...

  6. 15 CFR 1180.10 - NTIS permanent repository.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 15 Commerce and Foreign Trade 3 2010-01-01 2010-01-01 false NTIS permanent repository. 1180.10... ENGINEERING INFORMATION TO THE NATIONAL TECHNICAL INFORMATION SERVICE § 1180.10 NTIS permanent repository. A... repository as a service to agencies unless the Director advises the Liaison Officer that it has not been so...

  7. 76 FR 14028 - Center for Devices and Radiological Health 510(k) Implementation: Online Repository of Medical...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-15

    ...] Center for Devices and Radiological Health 510(k) Implementation: Online Repository of Medical Device... public meeting entitled ``510(k) Implementation: Discussion of an Online Repository of Medical Device... establish an online public repository of medical device labeling and strategies for displaying device...

  8. Identifying Tensions in the Use of Open Licenses in OER Repositories

    ERIC Educational Resources Information Center

    Amiel, Tel; Soares, Tiago Chagas

    2016-01-01

    We present an analysis of 50 repositories for educational content conducted through an "audit system" that helped us classify these repositories, their software systems, promoters, and how they communicated their licensing practices. We randomly accessed five resources from each repository to investigate the alignment of licensing…

  9. 10 CFR 63.113 - Performance objectives for the geologic repository after permanent closure.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Performance objectives for the geologic repository after...-LEVEL RADIOACTIVE WASTES IN A GEOLOGIC REPOSITORY AT YUCCA MOUNTAIN, NEVADA Technical Criteria Postclosure Performance Objectives § 63.113 Performance objectives for the geologic repository after permanent...

  10. 10 CFR 63.111 - Performance objectives for the geologic repository operations area through permanent closure.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Performance objectives for the geologic repository... (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN A GEOLOGIC REPOSITORY AT YUCCA MOUNTAIN, NEVADA... repository operations area through permanent closure. (a) Protection against radiation exposures and releases...

  11. 10 CFR 960.3-1 - Siting provisions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... REPOSITORY Implementation Guidelines § 960.3-1 Siting provisions. The siting provisions establish the... repositories. As required by the Act, § 960.3-1-3 specifies consideration of a regional distribution of repositories after recommendation of a site for development of the first repository. Section 960.3-1-4...

  12. 10 CFR 60.112 - Overall system performance objective for the geologic repository after permanent closure.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... repository after permanent closure. 60.112 Section 60.112 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES Technical Criteria Performance Objectives § 60.112 Overall system performance objective for the geologic repository after permanent closure...

  13. 10 CFR 60.132 - Additional design criteria for surface facilities in the geologic repository operations area.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... geologic repository operations area. 60.132 Section 60.132 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES Technical Criteria Design Criteria for the Geologic Repository Operations Area § 60.132 Additional design criteria for surface facilities in...

  14. 10 CFR 60.111 - Performance of the geologic repository operations area through permanent closure.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Performance of the geologic repository operations area... OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES Technical Criteria Performance Objectives § 60.111 Performance of the geologic repository operations area through permanent closure. (a...

  15. Institutional Repositories as Infrastructures for Long-Term Preservation

    ERIC Educational Resources Information Center

    Francke, Helena; Gamalielsson, Jonas; Lundell, Björn

    2017-01-01

    Introduction: The study describes the conditions for long-term preservation of the content of the institutional repositories of Swedish higher education institutions based on an investigation of how deposited files are managed with regards to file format and how representatives of the repositories describe the functions of the repositories.…

  16. Personal Name Identification in the Practice of Digital Repositories

    ERIC Educational Resources Information Center

    Xia, Jingfeng

    2006-01-01

    Purpose: To propose improvements to the identification of authors' names in digital repositories. Design/methodology/approach: Analysis of current name authorities in digital resources, particularly in digital repositories, and analysis of some features of existing repository applications. Findings: This paper finds that the variations of authors'…

  17. United States National Sewage Sludge Repository at Arizona State University--a new resource and research tool for environmental scientists, engineers, and epidemiologists.

    PubMed

    Venkatesan, Arjun K; Done, Hansa Y; Halden, Rolf U

    2015-02-01

    Processed municipal sewage sludges (MSS) are an abundant, unwanted by-product of wastewater treatment, increasingly applied to agriculture and forestry for inexpensive disposal and soil conditioning. Due to their high organic carbon and lipid contents, MSS not only is rich in carbon and nutrients but also represents a "sink" for recalcitrant, hydrophobic, and potentially bioaccumulative compounds. Indeed, many organics sequestered and concentrated in MSS meet the US Environmental Protection Agency's definition of being persistent, bioaccumulative, and toxic (PBT). In a strategic effort, our research team at the Biodesign Institute has created the National Sewage Sludge Repository (NSSR), a large repository of digested MSSs from 164 wastewater treatment plants from across the USA, as part of the Human Health Observatory (H2O) at Arizona State University (ASU). The NSSR likely represents the largest archive of digested MSS specimens in the USA. The present study summarizes key findings gleaned thus far from analysis of NSSR samples. For example, we evaluated the content of toxicants in MSS and computed estimates of nationwide inventories of mass produced chemicals that become sequestrated in sludge and later are released into the environment during sludge disposal on land. Ongoing efforts document co-occurrence of a variety of PBT compounds in both MSS and human samples, while also identifying a large number of potentially harmful MSS constituents for which human exposure data are still lacking. Finally, we summarize future opportunities and invite collaborative use of the NSSR by the research community. The H2O at ASU represents a new resource and research tool for environmental scientists and the larger research community. As illustrated in this work, this repository can serve to (i) identify and prioritize emerging contaminants, (ii) provide spatial and temporal trends of contaminants, (iii) inform and evaluate the effectiveness of environmental policy-making and regulations, and (iv) approximate, ongoing exposures and body burdens of mass-produced chemicals in human society.

  18. United States National Sewage Sludge Repository at Arizona State University – A New Resource and Research Tool for Environmental Scientists, Engineers, and Epidemiologists

    PubMed Central

    Venkatesan, Arjun K.; Done, Hansa Y.; Halden, Rolf U.

    2014-01-01

    Processed municipal sewage sludges (MSS) are an abundant, unwanted by-product of wastewater treatment, increasingly applied to agriculture and forestry for inexpensive disposal and soil conditioning. Due to their high organic-carbon and lipid contents, MSS not only is rich in carbon and nutrients but also represents a ‘sink’ for recalcitrant, hydrophobic and potentially bioaccumulative compounds. Indeed, many organics sequestered and concentrated in MSS meet the U.S. Environmental Protection Agency's definition of being persistent, bioaccumulative, and toxic (PBT). In a strategic effort, our research team at the Biodesign Institute has created the National Sewage Sludge Repository (NSSR), a large repository of digested MSSs from 164 wastewater treatment plants from across the USA, as part of the Human Health Observatory (H2O) at Arizona State University (ASU). The NSSR likely represents the largest archive of digested MSS specimens in the USA. The present study summarizes key findings gleaned thus far from analysis of NSSR samples. For example, we evaluated the content of toxicants in MSS and computed estimates of nationwide inventories of mass produced chemicals that become sequestrated in sludge and later are released into the environment during sludge disposal on land. Ongoing efforts document co-occurrence of a variety of PBT compounds in both MSS and human samples, while also identifying a large number of potentially harmful MSS constituents for which human exposure data are still lacking. Finally, we summarize new future opportunities and invite collaborative use the NSSR by the research community. The H2O at ASU represents a resource and research tool for environmental scientists and the larger research community. As illustrated in this work, this repository can serve to (i) identify and prioritize emerging contaminants; (ii) provide spatial and temporal trends of contaminants; (iii) inform and evaluate the effectiveness of environmental policy-making and regulations; and (iv) approximate, ongoing exposures and body burdens of mass-produced chemicals in human society. PMID:24824503

  19. Optimization of Deep Borehole Systems for HLW Disposal

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Driscoll, Michael; Baglietto, Emilio; Buongiorno, Jacopo

    2015-09-09

    This is the final report on a project to update and improve the conceptual design of deep boreholes for high level nuclear waste disposal. The effort was concentrated on application to intact US legacy LWR fuel assemblies, but conducted in a way in which straightforward extension to other waste forms, host rock types and countries was preserved. The reference fuel design version consists of a vertical borehole drilled into granitic bedrock, with the uppermost kilometer serving as a caprock zone containing a diverse and redundant series of plugs. There follows a one to two kilometer waste canister emplacement zone havingmore » a hole diameter of approximately 40-50 cm. Individual holes are spaced 200-300 m apart to form a repository field. The choice of verticality and the use of a graphite based mud as filler between the waste canisters and the borehole wall liner was strongly influenced by the expectation that retrievability would continue to be emphasized in US and worldwide repository regulatory criteria. An advanced version was scoped out using zinc alloy cast in place to fill void space inside a disposal canister and its encapsulated fuel assembly. This excludes water and greatly improves both crush resistance and thermal conductivity. However the simpler option of using a sand fill was found adequate and is recommended for near-term use. Thermal-hydraulic modeling of the low permeability and porosity host rock and its small (≤ 1%) saline water content showed that vertical convection induced by the waste’s decay heat should not transport nuclides from the emplacement zone up to the biosphere atop the caprock. First order economic analysis indicated that borehole repositories should be cost-competitive with shallower mined repositories. It is concluded that proceeding with plans to drill a demonstration borehole to confirm expectations, and to carry out priority experiments, such as retention and replenishment of in-hole water is in order.« less

  20. P19-S Managing Proteomics Data from Data Generation and Data Warehousing to Central Data Repository and Journal Reviewing Processes

    PubMed Central

    Thiele, H.; Glandorf, J.; Koerting, G.; Reidegeld, K.; Blüggel, M.; Meyer, H.; Stephan, C.

    2007-01-01

    In today’s proteomics research, various techniques and instrumentation bioinformatics tools are necessary to manage the large amount of heterogeneous data with an automatic quality control to produce reliable and comparable results. Therefore a data-processing pipeline is mandatory for data validation and comparison in a data-warehousing system. The proteome bioinformatics platform ProteinScape has been proven to cover these needs. The reprocessing of HUPO BPP participants’ MS data was done within ProteinScape. The reprocessed information was transferred into the global data repository PRIDE. ProteinScape as a data-warehousing system covers two main aspects: archiving relevant data of the proteomics workflow and information extraction functionality (protein identification, quantification and generation of biological knowledge). As a strategy for automatic data validation, different protein search engines are integrated. Result analysis is performed using a decoy database search strategy, which allows the measurement of the false-positive identification rate. Peptide identifications across different workflows, different MS techniques, and different search engines are merged to obtain a quality-controlled protein list. The proteomics identifications database (PRIDE), as a public data repository, is an archiving system where data are finally stored and no longer changed by further processing steps. Data submission to PRIDE is open to proteomics laboratories generating protein and peptide identifications. An export tool has been developed for transferring all relevant HUPO BPP data from ProteinScape into PRIDE using the PRIDE.xml format. The EU-funded ProDac project will coordinate the development of software tools covering international standards for the representation of proteomics data. The implementation of data submission pipelines and systematic data collection in public standards–compliant repositories will cover all aspects, from the generation of MS data in each laboratory to the conversion of all the annotating information and identifications to a standardized format. Such datasets can be used in the course of publishing in scientific journals.

  1. System and method for responding to ground and flight system malfunctions

    NASA Technical Reports Server (NTRS)

    Anderson, Julie J. (Inventor); Fussell, Ronald M. (Inventor)

    2010-01-01

    A system for on-board anomaly resolution for a vehicle has a data repository. The data repository stores data related to different systems, subsystems, and components of the vehicle. The data stored is encoded in a tree-based structure. A query engine is coupled to the data repository. The query engine provides a user and automated interface and provides contextual query to the data repository. An inference engine is coupled to the query engine. The inference engine compares current anomaly data to contextual data stored in the data repository using inference rules. The inference engine generates a potential solution to the current anomaly by referencing the data stored in the data repository.

  2. 17 CFR 49.9 - Duties of registered swap data repositories.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... privacy of any and all swap data and any other related information that the swap data repository receives... 17 Commodity and Securities Exchanges 2 2014-04-01 2014-04-01 false Duties of registered swap data... (CONTINUED) SWAP DATA REPOSITORIES § 49.9 Duties of registered swap data repositories. (a) Duties. To be...

  3. Availability and Accessibility in an Open Access Institutional Repository: A Case Study

    ERIC Educational Resources Information Center

    Lee, Jongwook; Burnett, Gary; Vandegrift, Micah; Baeg, Jung Hoon; Morris, Richard

    2015-01-01

    Introduction: This study explores the extent to which an institutional repository makes papers available and accessible on the open Web by using 170 journal articles housed in DigiNole Commons, the institutional repository at Florida State University. Method: To analyse the repository's impact on availability and accessibility, we conducted…

  4. The Use of Digital Repositories for Enhancing Teacher Pedagogical Performance

    ERIC Educational Resources Information Center

    Cohen, Anat; Kalimi, Sharon; Nachmias, Rafi

    2013-01-01

    This research examines the usage of local learning material repositories at school, as well as related teachers' attitudes and training. The study investigates the use of these repositories for enhancing teacher performance and assesses whether the assimilation of the local repositories increases their usage of and contribution to by teachers. One…

  5. Institutional Repositories in Indian Universities and Research Institutes: A Study

    ERIC Educational Resources Information Center

    Krishnamurthy, M.; Kemparaju, T. D.

    2011-01-01

    Purpose: The purpose of this paper is to report on a study of the institutional repositories (IRs) in use in Indian universities and research institutes. Design/methodology/approach: Repositories in various institutions in India were accessed and described in a standardised way. Findings: The 20 repositories studied covered collections of diverse…

  6. 10 CFR 63.161 - Emergency plan for the geologic repository operations area through permanent closure.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Emergency plan for the geologic repository operations area... OF HIGH-LEVEL RADIOACTIVE WASTES IN A GEOLOGIC REPOSITORY AT YUCCA MOUNTAIN, NEVADA Emergency Planning Criteria § 63.161 Emergency plan for the geologic repository operations area through permanent...

  7. 77 FR 26709 - Swap Data Repositories: Interpretative Statement Regarding the Confidentiality and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-07

    ... COMMODITY FUTURES TRADING COMMISSION 17 CFR Part 49 RIN 3038-AD83 Swap Data Repositories... data repositories (``SDRs'').SDRs are new registered entities created by section 728 of the Dodd-Frank... Act amends section 1a of the CEA to add a definition of the term ``swap data repository.'' Pursuant to...

  8. Online Paper Repositories and the Role of Scholarly Societies: An AERA Conference Report

    ERIC Educational Resources Information Center

    Educational Researcher, 2010

    2010-01-01

    This article examines issues faced by scholarly societies that are developing and sustaining online paper repositories. It is based on the AERA Conference on Online Paper Repositories, which focused on fundamental issues of policy and procedure important to the operations of online working paper repositories. The report and recommendations address…

  9. 10 CFR 960.3-2-2 - Nomination of sites as suitable for characterization.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... OF POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY Implementation Guidelines § 960.3-2-2 Nomination of... of each repository site. For the second repository, at least three of the sites shall not have been nominated previously. Any site nominated as suitable for characterization for the first repository, but not...

  10. Repositories for Research: Southampton's Evolving Role in the Knowledge Cycle

    ERIC Educational Resources Information Center

    Simpson, Pauline; Hey, Jessie

    2006-01-01

    Purpose: To provide an overview of how open access (OA) repositories have grown to take a premier place in the e-research knowledge cycle and offer Southampton's route from project to sustainable institutional repository. Design/methodology/approach: The evolution of institutional repositories and OA is outlined raising questions of multiplicity…

  11. Interoperability Across the Stewardship Spectrum in the DataONE Repository Federation

    NASA Astrophysics Data System (ADS)

    Jones, M. B.; Vieglais, D.; Wilson, B. E.

    2016-12-01

    Thousands of earth and environmental science repositories serve many researchers and communities, each with their own community and legal mandates, sustainability models, and historical infrastructure. These repositories span the stewardship spectrum from highly curated collections that employ large numbers of staff members to review and improve data, to small, minimal budget repositories that accept data caveat emptor and where all responsibility for quality lies with the submitter. Each repository fills a niche, providing services that meet the stewardship tradeoffs of one or more communities. We have reviewed these stewardship tradeoffs for several DataONE member repositories ranging from minimally (KNB) to highly curated (Arctic Data Center), as well as general purpose (Dryad) to highly discipline or project specific (NEON). The rationale behind different levels of stewardship reflect resolution of these tradeoffs. Some repositories aim to encourage extensive uptake by keeping processes simple and minimizing the amount of information collected, but this limits the long-term utility of the data and the search, discovery, and integration systems that are possible. Other repositories require extensive metadata input, review, and assessment, allowing for excellent preservation, discovery, and integration but at the cost of significant time for submitters and expense for curatorial staff. DataONE recognizes these different levels of curation, and attempts to embrace them to create a federation that is useful across the stewardship spectrum. DataONE provides a tiered model for repositories with growing utility of DataONE services at higher tiers of curation. The lowest tier supports read-only access to data and requires little more than title and contact metadata. Repositories can gradually phase in support for higher levels of metadata and services as needed. These tiered capabilities are possible through flexible support for multiple metadata standards and services, where repositories can incrementally increase their requirements as they want to satisfy more use cases. Within DataONE, metadata search services support minimal metadata models, but significantly expanded precision and recall become possible when repositories provide more extensively curated metadata.

  12. Optimizing Resources for Trustworthiness and Scientific Impact of Domain Repositories

    NASA Astrophysics Data System (ADS)

    Lehnert, K.

    2017-12-01

    Domain repositories, i.e. data archives tied to specific scientific communities, are widely recognized and trusted by their user communities for ensuring a high level of data quality, enhancing data value, access, and reuse through a unique combination of disciplinary and digital curation expertise. Their data services are guided by the practices and values of the specific community they serve and designed to support the advancement of their science. Domain repositories need to meet user expectations for scientific utility in order to be successful, but they also need to fulfill the requirements for trustworthy repository services to be acknowledged by scientists, funders, and publishers as a reliable facility that curates and preserves data following international standards. Domain repositories therefore need to carefully plan and balance investments to optimize the scientific impact of their data services and user satisfaction on the one hand, while maintaining a reliable and robust operation of the repository infrastructure on the other hand. Staying abreast of evolving repository standards to certify as a trustworthy repository and conducting a regular self-assessment and certification alone requires resources that compete with the demands for improving data holdings or usability of systems. The Interdisciplinary Earth Data Alliance (IEDA), a data facility funded by the US National Science Foundation, operates repositories for geochemical, marine Geoscience, and Antarctic research data, while also maintaining data products (global syntheses) and data visualization and analysis tools that are of high value for the science community and have demonstrated considerable scientific impact. Balancing the investments in the growth and utility of the syntheses with resources required for certifcation of IEDA's repository services has been challenging, and a major self-assessment effort has been difficult to accommodate. IEDA is exploring a partnership model to share generic repository functions (e.g. metadata registration, long-term archiving) with other repositories. This could substantially reduce the effort of certification and allow effort to focus on the domain-specific data curation and value-added services.

  13. Building Scientific Data's list of recommended data repositories

    NASA Astrophysics Data System (ADS)

    Hufton, A. L.; Khodiyar, V.; Hrynaszkiewicz, I.

    2016-12-01

    When Scientific Data launched in 2014 we provided our authors with a list of recommended data repositories to help them identify data hosting options that were likely to meet the journal's requirements. This list has grown in size and scope, and is now a central resource for authors across the Nature-titled journals. It has also been used in the development of data deposition policies and recommended repository lists across Springer Nature and at other publishers. Each new addition to the list is assessed according to a series of criteria that emphasize the stability of the resource, its commitment to principles of open science and its implementation of relevant community standards and reporting guidelines. A preference is expressed for repositories that issue digital object identifiers (DOIs) through the DataCite system and that share data under the Creative Commons CC0 waiver. Scientific Data currently lists fourteen repositories that focus on specific areas within the Earth and environmental sciences, as well as the broad scope repositories, Dryad and figshare. Readers can browse and filter datasets published at the journal by the host repository using ISA-explorer, a demo tool built by the ISA-tools team at Oxford University1. We believe that well-maintained lists like this one help publishers build a network of trust with community data repositories and provide an important complement to more comprehensive data repository indices and more formal certification efforts. In parallel, Scientific Data has also improved its policies to better support submissions from authors using institutional and project-specific repositories, without requiring each to apply for listing individually. Online resources Journal homepage: http://www.nature.com/scientificdata Data repository criteria: http://www.nature.com/sdata/policies/data-policies#repo-criteria Recommended data repositories: http://www.nature.com/sdata/policies/repositories Archived copies of the list: https://dx.doi.org/10.6084/m9.figshare.1434640.v6 Reference Gonzalez-Beltran, A. ISA-explorer: A demo tool for discovering and exploring Scientific Data's ISA-tab metadata. Scientific Data Updates http://blogs.nature.com/scientificdata/2015/12/17/isa-explorer/ (2015).

  14. The Emperor's New Repository

    ERIC Educational Resources Information Center

    Chudnov, Daniel

    2008-01-01

    The author does not know the first thing about building digital repositories. Maybe that is a strange thing to say, given that he works in a repository development group now, worked on the original DSpace project years ago, and worked on a few repository research projects in between. Given how long he has been around people and projects aiming to…

  15. Genetic conservation, characterization and utilization of wild relatives of fruit and nut crops at the USDA Germplasm Repository in Davis, California

    USDA-ARS?s Scientific Manuscript database

    The National Clonal Germplasm Repository (NCGR) in Davis is one among the nine repositories in the National Plant Germplasm System, USDA-ARS that is responsible for conservation of clonally propagated woody perennial subtropical and temperate fruit and nut crop germplasm. Currently the repository ho...

  16. 36 CFR 79.9 - Standards to determine when a repository possesses the capability to provide adequate long-term...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... repository possesses the capability to provide adequate long-term curatorial services. 79.9 Section 79.9... FEDERALLY-OWNED AND ADMINISTERED ARCHAEOLOGICAL COLLECTIONS § 79.9 Standards to determine when a repository... shall determine that a repository has the capability to provide adequate long-term curatorial services...

  17. 10 CFR Appendix II to Part 960 - NRC and EPA Requirements for Preclosure Repository Performance

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false NRC and EPA Requirements for Preclosure Repository... SCREENING OF POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY Pt. 960, App. II Appendix II to Part 960—NRC and EPA Requirements for Preclosure Repository Performance Under proposed 40 CFR part 191, subpart A...

  18. 10 CFR 51.109 - Public hearings in proceedings for issuance of materials license with respect to a geologic...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... license with respect to a geologic repository. 51.109 Section 51.109 Energy NUCLEAR REGULATORY COMMISSION... Public hearings in proceedings for issuance of materials license with respect to a geologic repository... waste repository at a geologic repository operations area under parts 60 and 63 of this chapter, and in...

  19. Semantic Linking of Learning Object Repositories to DBpedia

    ERIC Educational Resources Information Center

    Lama, Manuel; Vidal, Juan C.; Otero-Garcia, Estefania; Bugarin, Alberto; Barro, Senen

    2012-01-01

    Large-sized repositories of learning objects (LOs) are difficult to create and also to maintain. In this paper we propose a way to reduce this drawback by improving the classification mechanisms of the LO repositories. Specifically, we present a solution to automate the LO classification of the Universia repository, a collection of more than 15…

  20. 10 CFR Appendix I to Part 960 - NRC and EPA Requirements for Postclosure Repository Performance

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false NRC and EPA Requirements for Postclosure Repository... SCREENING OF POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY Pt. 960, App. I Appendix I to Part 960—NRC and EPA Requirements for Postclosure Repository Performance Under proposed 40 CFR part 191, subpart B...

  1. Desiderata for Healthcare Integrated Data Repositories Based on Architectural Comparison of Three Public Repositories

    PubMed Central

    Huser, Vojtech; Cimino, James J.

    2013-01-01

    Integrated data repositories (IDRs) are indispensable tools for numerous biomedical research studies. We compare three large IDRs (Informatics for Integrating Biology and the Bedside (i2b2), HMO Research Network’s Virtual Data Warehouse (VDW) and Observational Medical Outcomes Partnership (OMOP) repository) in order to identify common architectural features that enable efficient storage and organization of large amounts of clinical data. We define three high-level classes of underlying data storage models and we analyze each repository using this classification. We look at how a set of sample facts is represented in each repository and conclude with a list of desiderata for IDRs that deal with the information storage model, terminology model, data integration and value-sets management. PMID:24551366

  2. Desiderata for healthcare integrated data repositories based on architectural comparison of three public repositories.

    PubMed

    Huser, Vojtech; Cimino, James J

    2013-01-01

    Integrated data repositories (IDRs) are indispensable tools for numerous biomedical research studies. We compare three large IDRs (Informatics for Integrating Biology and the Bedside (i2b2), HMO Research Network's Virtual Data Warehouse (VDW) and Observational Medical Outcomes Partnership (OMOP) repository) in order to identify common architectural features that enable efficient storage and organization of large amounts of clinical data. We define three high-level classes of underlying data storage models and we analyze each repository using this classification. We look at how a set of sample facts is represented in each repository and conclude with a list of desiderata for IDRs that deal with the information storage model, terminology model, data integration and value-sets management.

  3. Radioactive waste management in the Federal Republic of Germany: Industrial practices and results

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Grabener, K.H.

    In the Federal Republic of Germany (FRG), the production and use of nuclear-generated electricity expanded steadily despite the fact that opposition from the environmentalists led to the impression of an upcoming moratorium for nuclear energy. With this increase in capacity--by the year 1990, nearly 25 000 MW will be on the line--there will be an increase in the volume of low-level (non-heat-generating) radwaste originating from nuclear power plants. Radwaste management has been influenced to a considerable extent by the requirements of the final repository. Following a period of trial storage in the Asse repository, preparations are now being made formore » storage in the Konrad ore mine. It is intended to begin storage in 1991. Requirements for the packages specify containers with a volume from 3.9 to 10.9 m/sup 3/ or cast iron safety drums. These drums are suitable for radioactive materials in powder form (resins, dried concentrates) without the need for embedding materials. Storage in standard 55-gal drums is no longer permitted. The costs for final storage will be very high so that volume reduction is of prime importance. Kraftwerk Union (KWU) as a supplier of nuclear power plants (NPPs) examined the radwaste market and decided to combine delivery of radwaste treatment systems to NPPs with service jobs including radwaste handling and conditioning in its own service and maintenance plant at Karlstein.« less

  4. Consequences of the Thermal Transient on the Evolution of the Damaged Zone Around a Repository for Heat-Emitting High-Level Radioactive Waste in a Clay Formation: a Performance Assessment Perspective

    NASA Astrophysics Data System (ADS)

    Yu, Li; Weetjens, Eef; Sillen, Xavier; Vietor, Tim; Li, Xiangling; Delage, Pierre; Labiouse, Vincent; Charlier, Robert

    2014-01-01

    A proper evaluation of the perturbations of the host rock induced by the excavation and the emplacement of exothermic wastes is essential for the assessment of the long-term safety of high-level radioactive waste disposals in clay formations. The impact of the thermal transient on the evolution of the damaged zone (DZ) has been explored in the European Commission project TIMODAZ (thermal impact on the damaged zone around a radioactive waste disposal in clay host rocks, 2006-2010). This paper integrates the scientific results of the TIMODAZ project from a performance assessment (PA) point of view, showing how these results support and justify key PA assumptions and the values of PA model parameters. This paper also contextualises the significance of the thermal impact on the DZ from a safety case perspective, highlighting how the project outcomes result into an improved understanding of the thermo-hydro-mechanical behaviour of the clay host rocks. The results obtained in the TIMODAZ project strengthen the assessment basis of the safety evaluation of the current repository designs. There was no evidence throughout the TIMODAZ experimental observations of a temperature-induced additional opening of fractures nor of a significant permeability increase of the DZ. Instead, thermally induced plasticity, swelling and creep seem to be beneficial to the sealing of fractures and to the recovery of a very low permeability in the DZ, close to that of an undisturbed clay host rock. Results from the TIMODAZ project indicate that the favourable properties of the clay host rock, which guarantee the effectiveness of the safety functions of the repository system, are expected to be maintained after the heating-cooling cycle. Hence, the basic assumptions usually made in PA calculations so far are expected to remain valid, and the performance of the system should not be affected in a negative way by the thermal evolution of the DZ around a radioactive waste repository in clay host rock.

  5. Challenges dealing with depleted uranium in Germany - Reuse or disposal

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Moeller, Kai D.

    2007-07-01

    During enrichment large amounts of depleted Uranium are produced. In Germany every year 2.800 tons of depleted uranium are generated. In Germany depleted uranium is not classified as radioactive waste but a resource for further enrichment. Therefore since 1996 depleted Uranium is sent to ROSATOM in Russia. However it still has to be dealt with the second generation of depleted Uranium. To evaluate the alternative actions in case a solution has to be found in Germany, several studies have been initiated by the Federal Ministry of the Environment. The work that has been carried out evaluated various possibilities to dealmore » with depleted uranium. The international studies on this field and the situation in Germany have been analyzed. In case no further enrichment is planned the depleted uranium has to be stored. In the enrichment process UF{sub 6} is generated. It is an international consensus that for storage it should be converted to U{sub 3}O{sub 8}. The necessary technique is well established. If the depleted Uranium would have to be characterized as radioactive waste, a final disposal would become necessary. For the planned Konrad repository - a repository for non heat generating radioactive waste - the amount of Uranium is limited by the licensing authority. The existing license would not allow the final disposal of large amounts of depleted Uranium in the Konrad repository. The potential effect on the safety case has not been roughly analyzed. As a result it may be necessary to think about alternatives. Several possibilities for the use of depleted uranium in the industry have been identified. Studies indicate that the properties of Uranium would make it useful in some industrial fields. Nevertheless many practical and legal questions are open. One further option may be the use as shielding e.g. in casks for transport or disposal. Possible techniques for using depleted Uranium as shielding are the use of the metallic Uranium as well as the inclusion in concrete. Another possibility could be the use of depleted uranium for the blending of High enriched Uranium (HEU) or with Plutonium to MOX-elements. (authors)« less

  6. Immobilization of selenate by iron in aqueous solution under anoxic conditions and the influence of uranyl

    NASA Astrophysics Data System (ADS)

    Puranen, Anders; Jonsson, Mats; Dähn, Rainer; Cui, Daqing

    2009-08-01

    In proposed high level radioactive waste repositories a large part of the spent nuclear fuel (SNF) canisters are commonly composed of iron. Selenium is present in spent nuclear fuel as a long lived fission product. This study investigates the influence of iron on the uptake of dissolved selenium in the form of selenate and the effect of the presence of dissolved uranyl on the above interaction of selenate. The iron oxide, and selenium speciation on the surfaces was investigated by Raman spectroscopy. X-ray Absorption Spectroscopy was used to determine the oxidation state of the selenium and uranium on the surfaces. Under the simulated groundwater conditions (10 mM NaCl, 2 mM NaHCO 3, <0.1 ppm O 2) the immobilized selenate was found to be reduced to oxidation states close to zero or lower and uranyl was found to be largely reduced to U(IV). The near simultaneous reduction of uranyl was found to greatly enhance the rate of selenate reduction. These findings suggest that the presence of uranyl being reduced by an iron surface could substantially enhance the rate of reduction of selenate under anoxic conditions relevant for a repository.

  7. Rapid methods for radionuclide contaminant transport in nuclear fuel cycle simulation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Huff, Kathryn

    Here, nuclear fuel cycle and nuclear waste disposal decisions are technologically coupled. However, current nuclear fuel cycle simulators lack dynamic repository performance analysis due to the computational burden of high-fidelity hydrolgic contaminant transport models. The Cyder disposal environment and repository module was developed to fill this gap. It implements medium-fidelity hydrologic radionuclide transport models to support assessment appropriate for fuel cycle simulation in the Cyclus fuel cycle simulator. Rapid modeling of hundreds of discrete waste packages in a geologic environment is enabled within this module by a suite of four closed form models for advective, dispersive, coupled, and idealized con-more » taminant transport: a Degradation Rate model, a Mixed Cell model, a Lumped Parameter model, and a 1-D Permeable Porous Medium model. A summary of the Cyder module, its timestepping algorithm, and the mathematical models implemented within it are presented. Additionally, parametric demonstrations simulations performed with Cyder are presented and shown to demonstrate functional agreement with parametric simulations conducted in a standalone hydrologic transport model, the Clay Generic Disposal System Model developed by the Used Fuel Disposition Campaign Department of Energy Office of Nuclear Energy.« less

  8. Rapid methods for radionuclide contaminant transport in nuclear fuel cycle simulation

    DOE PAGES

    Huff, Kathryn

    2017-08-01

    Here, nuclear fuel cycle and nuclear waste disposal decisions are technologically coupled. However, current nuclear fuel cycle simulators lack dynamic repository performance analysis due to the computational burden of high-fidelity hydrolgic contaminant transport models. The Cyder disposal environment and repository module was developed to fill this gap. It implements medium-fidelity hydrologic radionuclide transport models to support assessment appropriate for fuel cycle simulation in the Cyclus fuel cycle simulator. Rapid modeling of hundreds of discrete waste packages in a geologic environment is enabled within this module by a suite of four closed form models for advective, dispersive, coupled, and idealized con-more » taminant transport: a Degradation Rate model, a Mixed Cell model, a Lumped Parameter model, and a 1-D Permeable Porous Medium model. A summary of the Cyder module, its timestepping algorithm, and the mathematical models implemented within it are presented. Additionally, parametric demonstrations simulations performed with Cyder are presented and shown to demonstrate functional agreement with parametric simulations conducted in a standalone hydrologic transport model, the Clay Generic Disposal System Model developed by the Used Fuel Disposition Campaign Department of Energy Office of Nuclear Energy.« less

  9. A Framework for Integrating Oceanographic Data Repositories

    NASA Astrophysics Data System (ADS)

    Rozell, E.; Maffei, A. R.; Beaulieu, S. E.; Fox, P. A.

    2010-12-01

    Oceanographic research covers a broad range of science domains and requires a tremendous amount of cross-disciplinary collaboration. Advances in cyberinfrastructure are making it easier to share data across disciplines through the use of web services and community vocabularies. Best practices in the design of web services and vocabularies to support interoperability amongst science data repositories are only starting to emerge. Strategic design decisions in these areas are crucial to the creation of end-user data and application integration tools. We present S2S, a novel framework for deploying customizable user interfaces to support the search and analysis of data from multiple repositories. Our research methods follow the Semantic Web methodology and technology development process developed by Fox et al. This methodology stresses the importance of close scientist-technologist interactions when developing scientific use cases, keeping the project well scoped and ensuring the result meets a real scientific need. The S2S framework motivates the development of standardized web services with well-described parameters, as well as the integration of existing web services and applications in the search and analysis of data. S2S also encourages the use and development of community vocabularies and ontologies to support federated search and reduce the amount of domain expertise required in the data discovery process. S2S utilizes the Web Ontology Language (OWL) to describe the components of the framework, including web service parameters, and OpenSearch as a standard description for web services, particularly search services for oceanographic data repositories. We have created search services for an oceanographic metadata database, a large set of quality-controlled ocean profile measurements, and a biogeographic search service. S2S provides an application programming interface (API) that can be used to generate custom user interfaces, supporting data and application integration across these repositories and other web resources. Although initially targeted towards a general oceanographic audience, the S2S framework shows promise in many science domains, inspired in part by the broad disciplinary coverage of oceanography. This presentation will cover the challenges addressed by the S2S framework, the research methods used in its development, and the resulting architecture for the system. It will demonstrate how S2S is remarkably extensible, and can be generalized to many science domains. Given these characteristics, the framework can simplify the process of data discovery and analysis for the end user, and can help to shift the responsibility of search interface development away from data managers.

  10. The Role of Documentation Quality in Anesthesia-Related Closed Claims: A Descriptive Qualitative Study.

    PubMed

    Wilbanks, Bryan A; Geisz-Everson, Marjorie; Boust, Rebecca R

    2016-09-01

    Clinical documentation is a critical tool in supporting care provided to patients. Sound documentation provides a picture of clinical events that can be used to improve patient care. However, many other uses for clinical documentation are equally important. Such documentation informs clinical decision support tools, creates a legal record of patient care, assists in financial reimbursement of services, and serves as a repository for secondary data analysis. Conversely, poor documentation can impair patient safety and increase malpractice risk exposure by reflecting poor or inaccurate information that ultimately may guide patient care decisions.Through an examination of anesthesia-related closed claims, a descriptive qualitative study emerged, which explored the antecedents and consequences of documentation quality in the claims reviewed. A secondary data analysis utilized a database generated by the American Association of Nurse Anesthetists Foundation closed claim review team. Four major themes emerged from the analysis. Themes 1, 2, and 4 primarily describe how poor documentation quality can have negative consequences for clinicians. The third theme primarily describes how poor documentation quality that can negatively affect patient safety.

  11. Enabling comparative modeling of closely related genomes: Example genus Brucella

    DOE PAGES

    Faria, José P.; Edirisinghe, Janaka N.; Davis, James J.; ...

    2014-03-08

    For many scientific applications, it is highly desirable to be able to compare metabolic models of closely related genomes. In this study, we attempt to raise awareness to the fact that taking annotated genomes from public repositories and using them for metabolic model reconstructions is far from being trivial due to annotation inconsistencies. We are proposing a protocol for comparative analysis of metabolic models on closely related genomes, using fifteen strains of genus Brucella, which contains pathogens of both humans and livestock. This study lead to the identification and subsequent correction of inconsistent annotations in the SEED database, as wellmore » as the identification of 31 biochemical reactions that are common to Brucella, which are not originally identified by automated metabolic reconstructions. We are currently implementing this protocol for improving automated annotations within the SEED database and these improvements have been propagated into PATRIC, Model-SEED, KBase and RAST. This method is an enabling step for the future creation of consistent annotation systems and high-quality model reconstructions that will support in predicting accurate phenotypes such as pathogenicity, media requirements or type of respiration.« less

  12. Enabling comparative modeling of closely related genomes: Example genus Brucella

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Faria, José P.; Edirisinghe, Janaka N.; Davis, James J.

    For many scientific applications, it is highly desirable to be able to compare metabolic models of closely related genomes. In this study, we attempt to raise awareness to the fact that taking annotated genomes from public repositories and using them for metabolic model reconstructions is far from being trivial due to annotation inconsistencies. We are proposing a protocol for comparative analysis of metabolic models on closely related genomes, using fifteen strains of genus Brucella, which contains pathogens of both humans and livestock. This study lead to the identification and subsequent correction of inconsistent annotations in the SEED database, as wellmore » as the identification of 31 biochemical reactions that are common to Brucella, which are not originally identified by automated metabolic reconstructions. We are currently implementing this protocol for improving automated annotations within the SEED database and these improvements have been propagated into PATRIC, Model-SEED, KBase and RAST. This method is an enabling step for the future creation of consistent annotation systems and high-quality model reconstructions that will support in predicting accurate phenotypes such as pathogenicity, media requirements or type of respiration.« less

  13. 75 FR 26788 - Public Land Order No. 7742; Withdrawal of Public Land for the Manning Canyon Tailings Repository; UT

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-12

    ... 79765] Public Land Order No. 7742; Withdrawal of Public Land for the Manning Canyon Tailings Repository... period of 5 years to protect the integrity of the Manning Canyon Tailings Repository and surrounding... Repository. The Bureau of Land Management intends to evaluate the need for a lengthier withdrawal through the...

  14. Analysis of Academic Attitudes and Existing Processes to Inform the Design of Teaching and Learning Material Repositories: A User-Centred Approach

    ERIC Educational Resources Information Center

    King, Melanie; Loddington, Steve; Manuel, Sue; Oppenheim, Charles

    2008-01-01

    The last couple of years have brought a rise in the number of institutional repositories throughout the world and within UK Higher Education institutions, with the majority of these repositories being devoted to research output. Repositories containing teaching and learning material are less common and the workflows and business processes…

  15. Integrating XQuery-Enabled SCORM XML Metadata Repositories into an RDF-Based E-Learning P2P Network

    ERIC Educational Resources Information Center

    Qu, Changtao; Nejdl, Wolfgang

    2004-01-01

    Edutella is an RDF-based E-Learning P2P network that is aimed to accommodate heterogeneous learning resource metadata repositories in a P2P manner and further facilitate the exchange of metadata between these repositories based on RDF. Whereas Edutella provides RDF metadata repositories with a quite natural integration approach, XML metadata…

  16. Scaling an expert system data mart: more facilities in real-time.

    PubMed

    McNamee, L A; Launsby, B D; Frisse, M E; Lehmann, R; Ebker, K

    1998-01-01

    Clinical Data Repositories are being rapidly adopted by large healthcare organizations as a method of centralizing and unifying clinical data currently stored in diverse and isolated information systems. Once stored in a clinical data repository, healthcare organizations seek to use this centralized data to store, analyze, interpret, and influence clinical care, quality and outcomes. A recent trend in the repository field has been the adoption of data marts--specialized subsets of enterprise-wide data taken from a larger repository designed specifically to answer highly focused questions. A data mart exploits the data stored in the repository, but can use unique structures or summary statistics generated specifically for an area of study. Thus, data marts benefit from the existence of a repository, are less general than a repository, but provide more effective and efficient support for an enterprise-wide data analysis task. In previous work, we described the use of batch processing for populating data marts directly from legacy systems. In this paper, we describe an architecture that uses both primary data sources and an evolving enterprise-wide clinical data repository to create real-time data sources for a clinical data mart to support highly specialized clinical expert systems.

  17. Thermo-hydrological and chemical (THC) modeling to support Field Test Design

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Stauffer, Philip H.; Jordan, Amy B.; Harp, Dylan Robert

    This report summarizes ongoing efforts to simulate coupled thermal-hydrological-chemical (THC) processes occurring within a hypothetical high-level waste (HLW) repository in bedded salt. The report includes work completed since the last project deliverable, “Coupled model for heat and water transport in a high level waste repository in salt”, a Level 2 milestone submitted to DOE in September 2013 (Stauffer et al., 2013). Since the last deliverable, there have been code updates to improve the integration of the salt module with the pre-existing code and development of quality assurance (QA) tests of constitutive functions and precipitation/dissolution reactions. Simulations of bench-scale experiments, bothmore » historical and currently in the planning stages have been performed. Additional simulations have also been performed on the drift-scale model that incorporate new processes, such as an evaporation function to estimate water vapor removal from the crushed salt backfill and isotopic fractionation of water isotopes. Finally, a draft of a journal paper on the importance of clay dehydration on water availability is included as Appendix I.« less

  18. Actinide Solubility and Speciation in the WIPP [PowerPoint

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Reed, Donald T.

    2015-11-02

    The presentation begins with the role and need for nuclear repositories (overall concept, international updates (Sweden, Finland, France, China), US approach and current status), then moves on to the WIPP TRU repository concept (design, current status--safety incidents of February 5 and 14, 2014, path forward), and finally considers the WIPP safety case: dissolved actinide concentrations (overall approach, oxidation state distribution and redox control, solubility of actinides, colloidal contribution and microbial effects). The following conclusions are set forth: (1) International programs are moving forward, but at a very slow and somewhat sporadic pace. (2) In the United States, the Salt repositorymore » concept, from the perspective of the long-term safety case, remains a viable option for nuclear waste management despite the current operational issues/concerns. (3) Current model/PA prediction (WIPP example) are built on redundant conservatisms. These conservatisms are being addressed in the ongoing and future research to fill existing data gaps--redox control of plutonium by Fe(0, II), thorium (analog) solubility studies in simulated brine, contribution of intrinsic and biocolloids to the mobile concentration, and clarification of microbial ecology and effects.« less

  19. Future Volcanism at Yucca Mountain - Statistical Insights from the Non-Detection of Basalt Intrusions in the Potential Repository

    NASA Astrophysics Data System (ADS)

    Coleman, N.; Abramson, L.

    2004-05-01

    Yucca Mt. (YM) is a potential repository site for high-level radioactive waste and spent fuel. One issue is the potential for future igneous activity to intersect the repository. If the event probability is <1E-8/yr, it need not be considered in licensing. Plio-Quaternary volcanos and older basalts occur near YM. Connor et al (JGR, 2000) estimate a probability of 1E-8/yr to 1E-7/yr for a basaltic dike to intersect the potential repository. Based on aeromagnetic data, Hill and Stamatakos (CNWRA, 2002) propose that additional volcanos may lie buried in nearby basins. They suggest if these volcanos are part of temporal-clustered volcanic activity, the probability of an intrusion may be as high as 1E-6/yr. We examine whether recurrence probabilities >2E-7/yr are realistic given that no dikes have been found in or above the 1.3E7 yr-old potential repository block. For 2E-7/yr (or 1E-6/yr), the expected number of penetrating dikes is 2.6 (respectively, 13), and the probability of at least one penetration is 0.93 (0.999). These results are not consistent with the exploration evidence. YM is one of the most intensively studied places on Earth. Over 20 yrs of studies have included surface and subsurface mapping, geophysical surveys, construction of 10+ km of tunnels in the mountain, drilling of many boreholes, and construction of many pits (DOE, Site Recommendation, 2002). It seems unlikely that multiple dikes could exist within the proposed repository footprint and escape detection. A dike complex dated 11.7 Ma (Smith et al, UNLV, 1997) or 10 Ma (Carr and Parrish, 1985) does exist NW of YM and west of the main Solitario Canyon Fault. These basalts intruded the Tiva Canyon Tuff (12.7 Ma) in an epoch of caldera-forming pyroclastic eruptions that ended millions of yrs ago. We would conclude that basaltic volcanism related to Miocene silicic volcanism may also have ended. Given the nondetection of dikes in the potential repository, we can use a Poisson model to estimate an upper-bound probability of 2E-7/yr (95% conf. level) for an igneous intrusion over the next 1E4 yrs. If we assume one undiscovered dike exists, the upper-bound probability would rise to 4E-7/yr. Higher probabilities may be possible if conditions that fostered Plio-Quaternary volcanism became enhanced over time. To the contrary, basalts of the past 11 Ma in Crater Flat have erupted in four episodes that together show a declining trend in erupted magma volume (DOE, TBD13, 2003). Smith et al (GSA Today, 2002) suggest there may be a common magma source for volcanism in Crater Flat and the Lunar Crater volcanic field, and that recurrence rates for YM could be underestimated. Their interpretation is highly speculative given the 130-km (80-mi) distance between these zones. A claim that crustal extension at YM is anomalously large, possibly favoring renewed volcanism (Wernicke et al, Science, 1999), was contradicted by later work (Savage et al, JGR, 2000). Spatial-temporal models that predict future intrusion probabilities of >2E-7/yr may be overly conservative and unrealistic. Along with currently planned site characterization activities, realistic models could be developed by considering the non-detection of basaltic dikes in the potential repository footprint. (The views expressed are the authors' and do not reflect any final judgment or determination by the Advisory Committee on Nuclear Waste or the Nuclear Regulatory Commission regarding the matters addressed or the acceptability of a license application for a geologic repository at Yucca Mt.)

  20. Classification of Clinical Research Study Eligibility Criteria to Support Multi-Stage Cohort Identification Using Clinical Data Repositories.

    PubMed

    Cimino, James J; Lancaster, William J; Wyatt, Mathew C

    2017-01-01

    One of the challenges to using electronic health record (EHR) repositories for research is the difficulty mapping study subject eligibility criteria to the query capabilities of the repository. We sought to characterize criteria as "easy" (searchable in a typical repository), "hard" (requiring manual review of the record data), and "impossible" (not typically available in EHR repositories). We obtained 292 criteria from 20 studies available from Clinical Trials.gov and rated them according to our three types, plus a fourth "mixed" type. We had good agreement among three independent reviewers and chose 274 criteria that were characterized by single types for further analysis. The resulting analysis showed typical features of criteria that do and don't map to repositories. We propose that these features be used to guide researchers in specifying eligibility criteria to improve development of enrollment workflow, including the definition of EHR repository queries for self-service or analyst-mediated retrievals.

  1. Making Research Data Repositories Visible: The re3data.org Registry

    PubMed Central

    Pampel, Heinz; Vierkant, Paul; Scholze, Frank; Bertelmann, Roland; Kindling, Maxi; Klump, Jens; Goebelbecker, Hans-Jürgen; Gundlach, Jens; Schirmbacher, Peter; Dierolf, Uwe

    2013-01-01

    Researchers require infrastructures that ensure a maximum of accessibility, stability and reliability to facilitate working with and sharing of research data. Such infrastructures are being increasingly summarized under the term Research Data Repositories (RDR). The project re3data.org–Registry of Research Data Repositories–has begun to index research data repositories in 2012 and offers researchers, funding organizations, libraries and publishers an overview of the heterogeneous research data repository landscape. In July 2013 re3data.org lists 400 research data repositories and counting. 288 of these are described in detail using the re3data.org vocabulary. Information icons help researchers to easily identify an adequate repository for the storage and reuse of their data. This article describes the heterogeneous RDR landscape and presents a typology of institutional, disciplinary, multidisciplinary and project-specific RDR. Further the article outlines the features of re3data.org, and shows how this registry helps to identify appropriate repositories for storage and search of research data. PMID:24223762

  2. AdaNET phase 0 support for the AdaNET Dynamic Software Inventory (DSI) management system prototype. Catalog of available reusable software components

    NASA Technical Reports Server (NTRS)

    Hanley, Lionel

    1989-01-01

    The Ada Software Repository is a public-domain collection of Ada software and information. The Ada Software Repository is one of several repositories located on the SIMTEL20 Defense Data Network host computer at White Sands Missile Range, and available to any host computer on the network since 26 November 1984. This repository provides a free source for Ada programs and information. The Ada Software Repository is divided into several subdirectories. These directories are organized by topic, and their names and a brief overview of their topics are contained. The Ada Software Repository on SIMTEL20 serves two basic roles: to promote the exchange and use (reusability) of Ada programs and tools (including components) and to promote Ada education.

  3. Exploring Characterizations of Learning Object Repositories Using Data Mining Techniques

    NASA Astrophysics Data System (ADS)

    Segura, Alejandra; Vidal, Christian; Menendez, Victor; Zapata, Alfredo; Prieto, Manuel

    Learning object repositories provide a platform for the sharing of Web-based educational resources. As these repositories evolve independently, it is difficult for users to have a clear picture of the kind of contents they give access to. Metadata can be used to automatically extract a characterization of these resources by using machine learning techniques. This paper presents an exploratory study carried out in the contents of four public repositories that uses clustering and association rule mining algorithms to extract characterizations of repository contents. The results of the analysis include potential relationships between different attributes of learning objects that may be useful to gain an understanding of the kind of resources available and eventually develop search mechanisms that consider repository descriptions as a criteria in federated search.

  4. Environmental ethics and professional practice: A case study of an environmental challenge for century 2000

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Malone, C.

    1995-12-01

    Objective resolution of environmental issues involves questions of facts and values, and, for environmental issues to be resolved ethically, a proper synthesis of environmental facts with questions of ethics must occur. In this case study, the proposal by the U.S. Department of Energy (DOE) to use the Yucca Mountain site in southwest Nevada as a deep geologic repository for the permanent disposal of the nation`s high-level nuclear waste is examined in part in the context of the {open_quotes}Code of Ethics and Standards of Practice for Environmental Professionals{close_quotes} adopted by the National Association of Environmental Professionals (NAEP). Current plans are thatmore » a repository at the Yucca Mountain site would begin functioning in 2010 and would be sealed after about 150 years. The requirement that a geologic repository must isolate nuclear waste from the environment for at least 10,000 years poses unique challenges to environmental professionals. This case study also analyzes the challenges in terms of the implications of a new federal Executive Order on Ecosystem Management and corresponding internal orders within all federal agencies to conform to the Executive Order. The imposition of the principles and practices of ecosystem-based resource management on federal agencies provides an opportunity to also address, in the context of the DOE Yucca Mountain Project, (1) the ecosystem approach to environmental management, (2) concepts of holistic resource management planning, and (3) the concepts of sustainability and biodiversity. Within this framework there are important implications for environmental ethics and professional practice that must remain at the forefront of concerns of the NAEP over the next two decades.« less

  5. Results of instrument reliability study for high-level nuclear-waste repositories. [Geotechnical parameters

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rogue, F.; Binnall, E.P.

    1982-10-01

    Reliable instrumentation will be needed to monitor the performance of future high-level waste repository sites. A study has been made to assess instrument reliability at Department of Energy (DOE) waste repository related experiments. Though the study covers a wide variety of instrumentation, this paper concentrates on experiences with geotechnical instrumentation in hostile repository-type environments. Manufacturers have made some changes to improve the reliability of instruments for repositories. This paper reviews the failure modes, rates, and mechanisms, along with manufacturer modifications and recommendations for additional improvements to enhance instrument performance. 4 tables.

  6. Coupled Biological-Geomechanical-Geochemical Effects of the Disturbed Rock Zone on the Performance of the Waste Isolation Pilot Plant

    NASA Astrophysics Data System (ADS)

    Dunagan, S. C.; Herrick, C. G.; Lee, M. Y.

    2008-12-01

    The Waste Isolation Pilot Plant (WIPP) is located at a depth of 655 m in bedded salt in southeastern New Mexico and is operated by the U.S. Department of Energy as a deep underground disposal facility for transuranic (TRU) waste. The WIPP must comply with the EPA's environmental regulations that require a probabilistic risk analysis of releases of radionuclides due to inadvertent human intrusion into the repository at some time during the 10,000-year regulatory period. Sandia National Laboratories conducts performance assessments (PAs) of the WIPP using a system of computer codes representing the evolution of underground repository and emplaced TRU waste in order to demonstrate compliance. One of the important features modeled in a PA is the disturbed rock zone (DRZ) surrounding the emplacement rooms in the repository. The extent and permeability of DRZ play a significant role in the potential radionuclide release scenarios. We evaluated the phenomena occurring in the repository that affect the DRZ and their potential effects on the extent and permeability of the DRZ. Furthermore, we examined the DRZ's role in determining the performance of the repository. Pressure in the completely sealed repository will be increased by creep closure of the salt and degradation of TRU waste contents by microbial activity in the repository. An increased pressure in the repository will reduce the extent and permeability of the DRZ. The reduced DRZ extent and permeability will decrease the amount of brine that is available to interact with the waste. Furthermore, the potential for radionuclide release from the repository is dependent on the amount of brine that enters the repository. As a result of these coupled biological-geomechanical-geochemical phenomena, the extent and permeability of the DRZ has a significant impact on the potential radionuclide releases from the repository and, in turn, the repository performance. Sandia is a multi program laboratory operated by Sandia Corporation, a Lockheed Martin Company, for the United States Department of Energy's National Nuclear Security Administration under Contract DE-AC04- 94AL85000. This research is funded by WIPP programs administered by the Office of Environmental Management (EM) of the U.S. Department of Energy.

  7. The French Geological Repository Project Cigeo - 12023

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Harman, Alain; Labalette, Thibaud; Dupuis, Marie-Claude

    The French Agency for Radioactive Waste Management, ANDRA, was launched by law in 1991 to perform and develop the research programme for managing high level and intermediate level long-lived radioactive waste generated by the French nuclear fleet. After a 15-year intensive research programme, including the study of alternative solutions, an overall review and assessment of the results was organized, including a national public debate. As a result, the Parliament passed a Planning Act on radioactive waste management in 2006. Commissioning of a geological repository by 2025 was one of the most important decisions taken at that time. To reach thismore » goal, a license application must be submitted and reviewed by the competent authorities by 2015. A detailed review and consultation process is, as well, defined in the Planning Act. Beside the legal framework the project needs to progress on two fronts. The first one is on siting. A significant milestone was reached in 2009 with the definition of a defined area to locate the underground repository facilities. This area was approved in March 2010 by the Government, after having collected the opinions and positions of all the interested parties, at both National and local levels. A new phase of dialogue with local players began to refine the implementation scenarios of surface facilities. The final site selection will be approved after a public debate planned for 2013. The second one is the industrial organization, planning and costing. The industrial project of this geological repository was called Cigeo (Centre Industriel de Stockage Geologique). Given the amount of work to be done to comply with the given time framework, a detailed organization with well-defined milestones must be set-up. Cigeo will be a specific nuclear facility, built and operated underground for over a hundred years. The consequence of this long duration is that the development of the repository facilities will take place in successive operational phases. The characteristics of the first waste packages received will determine the work and the corresponding investments by 2025 on the repository site. One of the main challenges will be to accommodate both activities of mining and nuclear operations at the same time and at the same location. From the technical standpoint, ventilation and fire risk cannot be managed through a simple transposition from current nuclear industry practices. The reversibility demand also leads to concrete proposals with regard to repository management flexibility and waste package retrievability. These proposals contribute to the dialogue with stakeholders to prepare for the public debate and a future law which will determine the reversibility conditions. New design developments are expected to be introduced in the application from the current studies conducted until 2014. The possibility of optimization beyond 2015 will be kept open taking into account the one hundred years operating time as well as the capability to integrate feedback gained from the first construction and operation works. The industrial committed work aims to reach the application stage by 2015. The license application procedure was defined by the 2006 Act. Subject to authorization, the construction might begin in 2017. (authors)« less

  8. Repository Profiles for Atmospheric and Climate Sciences: Capabilities and Trends in Data Services

    NASA Astrophysics Data System (ADS)

    Hou, C. Y.; Thompson, C. A.; Palmer, C. L.

    2014-12-01

    As digital research data proliferate and expectations for open access escalate, the landscape of data repositories is becoming more complex. For example, DataBib currently identifies 980 data repositories across the disciplines, with 117 categorized under Geosciences. In atmospheric and climate sciences, there are great expectations for the integration and reuse of data for advancing science. To realize this potential, resources are needed that explicate the range of repository options available for locating and depositing open data, their conditions of access and use, and the services and tools they provide. This study profiled 38 open digital repositories in the atmospheric and climate sciences, analyzing each on 55 criteria through content analysis of their websites. The results provide a systematic way to assess and compare capabilities, services, and institutional characteristics and identify trends across repositories. Selected results from the more detailed outcomes to be presented: Most repositories offer guidance on data format(s) for submission and dissemination. 42% offer authorization-free access. More than half use some type of data identification system such as DOIs. Nearly half offer some data processing, with a similar number providing software or tools. 78.9% request that users cite or acknowledge datasets used and the data center. Only 21.1% recommend specific metadata standards, such as ISO 19115 or Dublin Core, with more than half utilizing a customized metadata scheme. Information was rarely provided on repository certification and accreditation and uneven for transfer of rights and data security. Few provided policy information on preservation, migration, reappraisal, disposal, or long-term sustainability. As repository use increases, it will be important for institutions to make their procedures and policies explicit, to build trust with user communities and improve efficiencies in data sharing. Resources such as repository profiles will be essential for scientists to weigh options and understand trends in data services across the evolving network of repositories.

  9. Corticotropin, Repository Injection

    MedlinePlus

    Corticotropin repository injection is used to treat the following conditions:infantile spasms (seizures that usually begin during the first ... of the arms, hands, feet, and legs). Corticotropin repository injection is in a class of medications called ...

  10. 10 CFR 60.134 - Design of seals for shafts and boreholes.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... GEOLOGIC REPOSITORIES Technical Criteria Design Criteria for the Geologic Repository Operations Area § 60... the geologic repository's ability to meet the performance objectives or the period following permanent...

  11. 10 CFR 960.5-2 - Technical guidelines.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... REPOSITORY Preclosure Guidelines § 960.5-2 Technical guidelines. The technical guidelines in this subpart set... repository and to the transportation of waste to a repository site. The third group includes conditions on...

  12. Environmental assessment: Davis Canyon site, Utah

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    none,

    1986-05-01

    In February 1983, the US Department of Energy (DOE) identified the Davis Canyon site in Utah as one of the nine potentially acceptable sites for a mined geologic repository for spent nuclear fuel and high-level radioactive waste. To determine their suitability, the Davis Canyon site and the eight other potentially acceptable sites have been evaluated in accordance with the DOE's General Guidelines for the Recommendation of Sites for the Nuclear Waste Repositories. These evaluations were reported in draft environmental assessments (EAs), which were issued for public review and comment. After considering the comments received on the draft EAs, the DOEmore » prepared the final EA. The Davis Canyon site is in the Paradox Basin, which is one of five distinct geohydrologic settings considered for the first repository. This setting contains one other potentially acceptable site -- the Lavender Canyon site. Although the Lavender Canyon site is suitable for site characterization, the DOE has concluded that the Davis Canyon site is the preferred site in the Paradox Basin. On the basis of the evaluations reported in this EA, the DOE has found that the Davis Canyon site is not disqualified under the guidelines. Furthermore, the DOE has fond that the site is suitable for site characterization because the evidence does not support a conclusion that the site will not be able to meet each of the qualifying conditions specified in the guidelines. On the basis of these findings, the DOE is nominating the Davis Canyon site as one of five sites suitable for characterization. 181 figs., 175 tabs.« less

  13. End of FY10 report - used fuel disposition technical bases and lessons learned : legal and regulatory framework for high-level waste disposition in the United States.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Weiner, Ruth F.; Blink, James A.; Rechard, Robert Paul

    This report examines the current policy, legal, and regulatory framework pertaining to used nuclear fuel and high level waste management in the United States. The goal is to identify potential changes that if made could add flexibility and possibly improve the chances of successfully implementing technical aspects of a nuclear waste policy. Experience suggests that the regulatory framework should be established prior to initiating future repository development. Concerning specifics of the regulatory framework, reasonable expectation as the standard of proof was successfully implemented and could be retained in the future; yet, the current classification system for radioactive waste, including hazardousmore » constituents, warrants reexamination. Whether or not consideration of multiple sites are considered simultaneously in the future, inclusion of mechanisms such as deliberate use of performance assessment to manage site characterization would be wise. Because of experience gained here and abroad, diversity of geologic media is not particularly necessary as a criterion in site selection guidelines for multiple sites. Stepwise development of the repository program that includes flexibility also warrants serious consideration. Furthermore, integration of the waste management system from storage, transportation, and disposition, should be examined and would be facilitated by integration of the legal and regulatory framework. Finally, in order to enhance acceptability of future repository development, the national policy should be cognizant of those policy and technical attributes that enhance initial acceptance, and those policy and technical attributes that maintain and broaden credibility.« less

  14. Solubility constants of hydroxyl sodalite at elevated temperatures evaluated from hydrothermal experiments: Applications to nuclear waste isolation

    DOE PAGES

    Xiong, Yongliang

    2016-09-17

    In this study, solubility constants of hydroxyl sodalite (ideal formula, Na 8[Al 6Si 6O 24][OH] 2·3H 2O) from 25°C to 100°C are obtained by applying a high temperature Al—Si Pitzer model to evaluate solubility data on hydroxyl sodalite in high ionic strength solutions at elevated temperatures. A validation test comparing model-independent experimental data to model predictions demonstrates that the solubility values produced by the model are in excellent agreement with the experimental data. In addition, the equilibrium constants obtained in this study have a wide range of applications, including synthesis of hydroxyl sodalite, de-silication in the Bayer process for extractionmore » of alumina, and the performance of proposed sodalite waste forms in geological repositories in various lithologies including salt formations. The thermodynamic calculations based on the equilibrium constants obtained in this work indicate that the solubility products in terms of m ΣAl×m ΣSi for hydroxyl sodalite are very low (e.g., ~10 -13 [mol·kg -1] 2 at 100°C) in brines characteristic of salt formations, implying that sodalite waste forms would perform very well in repositories located in salt formations. Finally, the information regarding the solubility behavior of hydroxyl sodalite obtained in this study provides guidance to investigate the performance of other pure end-members of sodalite such as chloride- and iodide-sodalite, which may be of interest for geological repositories in various media.« less

  15. Environmental assessment: Davis Canyon site, Utah

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    none,

    1986-05-01

    In February 1983, the US Department of Energy (DOE) identified the Davis Canyon site in Utah as one of the nine potentially acceptable sites for a mined geologic repository for spent nuclear fuel and high- level radioactive waste. To determine their suitability, the Davis Canyon site and the eight other potentially acceptable sites have been evaluated in accordance with the DOE's General Guidelines for the Recommendation of Sites for the Nuclear Waste Repositories. These evaluations were reported in draft environmental assessments (EAs), which were issued for public review and comment. After considering the comments received on the draft EAs, themore » DOE prepared the final EA. The Davis Canyon site is in the Paradox Basin, which is one of five distinct geohydrologic settings considered for the first repository. This setting contains one other potentially acceptable site -- the Lavender Canyon site. Although the Lavender Canyon site is suitable for site characterization, the DOE has concluded that the Davis Canyon site is the preferred site in the Paradox Basin. On the basis of the evaluations reported in this EA, the DOE has found that the Davis Canyon site is not disqualified under the guidelines. Furthermore, the DOE has found that the site is suitable for site characterization because the evidence does not support a conclusion that the site will not be able to meet each of the qualifying conditions specified in the guidelines. On the basis of these findings, the DOE is nominating the Davis Canyon site as one of the five sites suitable for characterization.« less

  16. Alternatives for managing wastes from reactors and post-fission operations in the LWR fuel cycle. Volume 5. Appendices

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1976-05-01

    Volume V of the five-volume report consists of appendices, which provide supplementary information, with emphasis on characteristics of geologic formations that might be used for final storage or disposal. Appendix titles are: selected glossary; conversion factors; geologic isolation, including, (a) site selection factors for repositories of wastes in geologic media, (b) rock types--geologic occurrence, (c) glossary of geohydrologic terms, and (d) 217 references; the ocean floor; and, government regulations pertaining to the management of radioactive materials. (JGB)

  17. How to Manage Rejected Scientific Papers? UNAIS as Final Solution.

    PubMed

    Diana, Alessandro

    2012-01-01

    Before publication, biomedical papers might undergo a very complex process, from journal selection, authors' motivations for submissions, modifications, and final publication or refusal. UNAIS (Unpublished Articles In Science) is an online repository in which authors can publish previously rejected scientific articles or articles that have never been submitted for publication. At UNAIS, authors can also publish the reasons behind the refusals to publication. UNAIS is more than an e-journal: it is a scientific drop box in which scientists can find indicative and negative results, as well as ideas that can inspire others. UNAIS's goal is also to help students and scientists who want to learn how to write scientific articles. UNAIS' aim is to exchange and promote knowledge. Have a look on www.unais.net.

  18. Downgrade of the Savannah River Sites FB-Line

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    SADOWSKI, ED; YOURCHAK, RANDY; PRETZELLO MARJI

    2005-07-05

    This paper will discuss the Safeguards & Security (S&S) activities that resulted in the downgrade of the Savannah River Site's FB-Line (FBL) from a Category I Material Balance Area (MBA) in a Material Access Area (MAA) to a Category IV MBA in a Property Protection Area (PPA). The Safeguards activities included measurement of final product items, transferal of nuclear material to other Savannah River Site (SRS) facilities, discard of excess nuclear material items, and final measurements of holdup material. The Security activities included relocation and destruction of classified documents and repositories, decertification of a classified computer, access control changes, updatesmore » to planning documents, deactivation and removal of security systems, Human Reliability Program (HRP) removals, and information security training for personnel that will remain in the FBL PPA.« less

  19. Assessing repository technology. Where do we go from here?

    NASA Technical Reports Server (NTRS)

    Eichmann, David

    1992-01-01

    Three sample information retrieval systems, archie, autoLib, and Wide Area Information Service (WAIS), are compared with regard to their expressiveness and usefulness, first in the general context of information retrieval, and then as prospective software reuse repositories. While the representational capabilities of these systems are limited, they provide a useful foundation for future repository efforts, particularly from the perspective of repository distribution and coherent user interface design.

  20. Assessing repository technology: Where do we go from here?

    NASA Technical Reports Server (NTRS)

    Eichmann, David A.

    1992-01-01

    Three sample information retrieval systems, archie, autoLib, and Wide Area Information Service (WAIS), are compared with regard to their expressiveness and usefulness, first in the general context of information retrieval, and then as perspective software reuse repositories. While the representational capabilities of these systems are limited, they provide a useful foundation for future repository efforts, particularly from the perspective of repository distribution and coherent user interface design.

  1. USAF Hearing Conservation Program, DOEHRS-HC Data Repository Annual Report: CY15

    DTIC Science & Technology

    2017-05-31

    AFRL-SA-WP-SR-2017-0014 USAF Hearing Conservation Program, DOEHRS-HC Data Repository Annual Report: CY15 Daniel A. Williams...Conservation Program, DOEHRS-HC Data Repository Annual Report: CY15 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR...Health Readiness System-Hearing Conservation Data Repository (DOEHRS-HC DR). Major command- and installation-level reports are available quarterly

  2. 10 CFR 960.3-4 - Environmental impacts.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... REPOSITORY Implementation Guidelines § 960.3-4 Environmental impacts. Environmental impacts shall be considered by the DOE throughout the site characterization, site selection, and repository development..., during site characterization and repository construction, operation, closure, and decommissioning. ...

  3. Uncertainty and sensitivity analysis for two-phase flow in the vicinity of the repository in the 1996 performance assessment for the Waste Isolation Pilot Plant: Disturbed conditions

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    HELTON,JON CRAIG; BEAN,J.E.; ECONOMY,K.

    2000-05-22

    Uncertainty and sensitivity analysis results obtained in the 1996 performance assessment (PA) for the Waste Isolation Pilot Plant (WIPP) are presented for two-phase flow in the vicinity of the repository under disturbed conditions resulting from drilling intrusions. Techniques based on Latin hypercube sampling, examination of scatterplots, stepwise regression analysis, partial correlation analysis and rank transformations are used to investigate brine inflow, gas generation repository pressure, brine saturation and brine and gas outflow. Of the variables under study, repository pressure and brine flow from the repository to the Culebra Dolomite are potentially the most important in PA for the WIPP. Subsequentmore » to a drilling intrusion repository pressure was dominated by borehole permeability and generally below the level (i.e., 8 MPa) that could potentially produce spallings and direct brine releases. Brine flow from the repository to the Culebra Dolomite tended to be small or nonexistent with its occurrence and size also dominated by borehole permeability.« less

  4. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ferrada, J.J.

    This report compiles preliminary information that supports the premise that a repository is needed in Latin America and analyzes the nuclear situation (mainly in Argentina and Brazil) in terms of nuclear capabilities, inventories, and regional spent-fuel repositories. The report is based on several sources and summarizes (1) the nuclear capabilities in Latin America and establishes the framework for the need of a permanent repository, (2) the International Atomic Energy Agency (IAEA) approach for a regional spent-fuel repository and describes the support that international institutions are lending to this issue, (3) the current situation in Argentina in order to analyze themore » Argentinean willingness to find a location for a deep geological repository, and (4) the issues involved in selecting a location for the repository and identifies a potential location. This report then draws conclusions based on an analysis of this information. The focus of this report is mainly on spent fuel and does not elaborate on other radiological waste sources.« less

  5. Influence analysis of Github repositories.

    PubMed

    Hu, Yan; Zhang, Jun; Bai, Xiaomei; Yu, Shuo; Yang, Zhuo

    2016-01-01

    With the support of cloud computing techniques, social coding platforms have changed the style of software development. Github is now the most popular social coding platform and project hosting service. Software developers of various levels keep entering Github, and use Github to save their public and private software projects. The large amounts of software developers and software repositories on Github are posing new challenges to the world of software engineering. This paper tries to tackle one of the important problems: analyzing the importance and influence of Github repositories. We proposed a HITS based influence analysis on graphs that represent the star relationship between Github users and repositories. A weighted version of HITS is applied to the overall star graph, and generates a different set of top influential repositories other than the results from standard version of HITS algorithm. We also conduct the influential analysis on per-month star graph, and study the monthly influence ranking of top repositories.

  6. Biological Web Service Repositories Review

    PubMed Central

    Urdidiales‐Nieto, David; Navas‐Delgado, Ismael

    2016-01-01

    Abstract Web services play a key role in bioinformatics enabling the integration of database access and analysis of algorithms. However, Web service repositories do not usually publish information on the changes made to their registered Web services. Dynamism is directly related to the changes in the repositories (services registered or unregistered) and at service level (annotation changes). Thus, users, software clients or workflow based approaches lack enough relevant information to decide when they should review or re‐execute a Web service or workflow to get updated or improved results. The dynamism of the repository could be a measure for workflow developers to re‐check service availability and annotation changes in the services of interest to them. This paper presents a review on the most well‐known Web service repositories in the life sciences including an analysis of their dynamism. Freshness is introduced in this paper, and has been used as the measure for the dynamism of these repositories. PMID:27783459

  7. Creation of Data Repositories to Advance Nursing Science.

    PubMed

    Perazzo, Joseph; Rodriguez, Margaret; Currie, Jackson; Salata, Robert; Webel, Allison R

    2017-12-01

    Data repositories are a strategy in line with precision medicine and big data initiatives, and are an efficient way to maximize data utility and form collaborative research relationships. Nurse researchers are uniquely positioned to make a valuable contribution using this strategy. The purpose of this article is to present a review of the benefits and challenges associated with developing data repositories, and to describe the process we used to develop and maintain a data repository in HIV research. Systematic planning, data collection, synthesis, and data sharing have enabled us to conduct robust cross-sectional and longitudinal analyses with more than 200 people living with HIV. Our repository building has also led to collaboration and training, both in and out of our organization. We present a pragmatic and affordable way that nurse scientists can build and maintain a data repository, helping us continue to make to our understanding of health phenomena.

  8. Classifying Clinical Trial Eligibility Criteria to Facilitate Phased Cohort Identification Using Clinical Data Repositories.

    PubMed

    Wang, Amy Y; Lancaster, William J; Wyatt, Matthew C; Rasmussen, Luke V; Fort, Daniel G; Cimino, James J

    2017-01-01

    A major challenge in using electronic health record repositories for research is the difficulty matching subject eligibility criteria to query capabilities of the repositories. We propose categories for study criteria corresponding to the effort needed for querying those criteria: "easy" (supporting automated queries), mixed (initial automated querying with manual review), "hard" (fully manual record review), and "impossible" or "point of enrollment" (not typically in health repositories). We obtained a sample of 292 criteria from 20 studies from ClinicalTrials.gov. Six independent reviewers, three each from two academic research institutions, rated criteria according to our four types. We observed high interrater reliability both within and between institutions. The analysis demonstrated typical features of criteria that map with varying levels of difficulty to repositories. We propose using these features to improve enrollment workflow through more standardized study criteria, self-service repository queries, and analyst-mediated retrievals.

  9. Space Telecommunications Radio System (STRS) Application Repository Design and Analysis

    NASA Technical Reports Server (NTRS)

    Handler, Louis M.

    2013-01-01

    The Space Telecommunications Radio System (STRS) Application Repository Design and Analysis document describes the STRS application repository for software-defined radio (SDR) applications intended to be compliant to the STRS Architecture Standard. The document provides information about the submission of artifacts to the STRS application repository, to provide information to the potential users of that information, and for the systems engineer to understand the requirements, concepts, and approach to the STRS application repository. The STRS application repository is intended to capture knowledge, documents, and other artifacts for each waveform application or other application outside of its project so that when the project ends, the knowledge is retained. The document describes the transmission of technology from mission to mission capturing lessons learned that are used for continuous improvement across projects and supporting NASA Procedural Requirements (NPRs) for performing software engineering projects and NASAs release process.

  10. [The subject repositories of strategy of the Open Access initiative].

    PubMed

    Soares Guimarães, M C; da Silva, C H; Horsth Noronha, I

    2012-11-01

    The subject repositories are defined as a set of digital objects resulting from the research related to a specific disciplinary field and occupy a still restricted space in the discussion agenda of the Free Access Movement when compared to amplitude reached in the discussion of Institutional Repositories. Although the Subject Repository comes to prominence in the field, especially for the success of initiatives such as the arXiv, PubMed and E-prints, the literature on the subject is recognized as very limited. Despite its roots in the Library and Information Science, and focus on the management of disciplinary collections (subject area literature), there is little information available about the development and management of subject repositories. The following text seeks to make a brief summary on the topic as a way to present the potential to develop subject repositories in order to strengthen the initiative of open access.

  11. Classifying Clinical Trial Eligibility Criteria to Facilitate Phased Cohort Identification Using Clinical Data Repositories

    PubMed Central

    Wang, Amy Y.; Lancaster, William J.; Wyatt, Matthew C.; Rasmussen, Luke V.; Fort, Daniel G.; Cimino, James J.

    2017-01-01

    A major challenge in using electronic health record repositories for research is the difficulty matching subject eligibility criteria to query capabilities of the repositories. We propose categories for study criteria corresponding to the effort needed for querying those criteria: “easy” (supporting automated queries), mixed (initial automated querying with manual review), “hard” (fully manual record review), and “impossible” or “point of enrollment” (not typically in health repositories). We obtained a sample of 292 criteria from 20 studies from ClinicalTrials.gov. Six independent reviewers, three each from two academic research institutions, rated criteria according to our four types. We observed high interrater reliability both within and between institutions. The analysis demonstrated typical features of criteria that map with varying levels of difficulty to repositories. We propose using these features to improve enrollment workflow through more standardized study criteria, self-service repository queries, and analyst-mediated retrievals. PMID:29854246

  12. A Safety Case Approach for Deep Geologic Disposal of DOE HLW and DOE SNF in Bedded Salt - 13350

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sevougian, S. David; MacKinnon, Robert J.; Leigh, Christi D.

    2013-07-01

    The primary objective of this study is to investigate the feasibility and utility of developing a defensible safety case for disposal of United States Department of Energy (U.S. DOE) high-level waste (HLW) and DOE spent nuclear fuel (SNF) in a conceptual deep geologic repository that is assumed to be located in a bedded salt formation of the Delaware Basin [1]. A safety case is a formal compilation of evidence, analyses, and arguments that substantiate and demonstrate the safety of a proposed or conceptual repository. We conclude that a strong initial safety case for potential licensing can be readily compiled bymore » capitalizing on the extensive technical basis that exists from prior work on the Waste Isolation Pilot Plant (WIPP), other U.S. repository development programs, and the work published through international efforts in salt repository programs such as in Germany. The potential benefits of developing a safety case include leveraging previous investments in WIPP to reduce future new repository costs, enhancing the ability to effectively plan for a repository and its licensing, and possibly expediting a schedule for a repository. A safety case will provide the necessary structure for organizing and synthesizing existing salt repository science and identifying any issues and gaps pertaining to safe disposal of DOE HLW and DOE SNF in bedded salt. The safety case synthesis will help DOE to plan its future R and D activities for investigating salt disposal using a risk-informed approach that prioritizes test activities that include laboratory, field, and underground investigations. It should be emphasized that the DOE has not made any decisions regarding the disposition of DOE HLW and DOE SNF. Furthermore, the safety case discussed herein is not intended to either site a repository in the Delaware Basin or preclude siting in other media at other locations. Rather, this study simply presents an approach for accelerated development of a safety case for a potential DOE HLW and DOE SNF repository using the currently available technical basis for bedded salt. This approach includes a summary of the regulatory environment relevant to disposal of DOE HLW and DOE SNF in a deep geologic repository, the key elements of a safety case, the evolution of the safety case through the successive phases of repository development and licensing, and the existing technical basis that could be used to substantiate the safety of a geologic repository if it were to be sited in the Delaware Basin. We also discuss the potential role of an underground research laboratory (URL). (authors)« less

  13. New Features of the re3data Registry of Research Data Repositories

    NASA Astrophysics Data System (ADS)

    Elger, K.; Pampel, H.; Vierkant, P.; Witt, M.

    2016-12-01

    re3data is a registry of research data repositories that lists over 1,600 repositories from around the world, making it the largest and most comprehensive online catalog of data repositories on the web. The registry offers researchers, funding agencies, libraries and publishers a comprehensive overview of the heterogeneous landscape of data repositories. The repositories are described, following the "Metadata Schema for the Description of Research Data Repositories". re3data summarises the properties of a repository into a user-friendly icon system helping users to easily identify an adequate repository for the storage of their datasets. The re3data entries are curated by an international, multi-disciplinary editorial board. An application programming interface (API) enables other information systems to list and fetch metadata for integration and interoperability. Funders like the European Commission (2015) and publishers like Springer Nature (2016) recommend the use of re3data.org in their policies. The original re3data project partners are the GFZ German Research Centre for Geosciences, the Humboldt-Universität zu Berlin, the Purdue University Libraries and the Karlsruhe Institute of Technology (KIT). Since 2015 re3data is operated as a service of DataCite, a global non-profit organisation that provides persistent identifiers (DOIs) for research data. At the 2016 AGU Fall Meeting we will describe the current status of re3data. An overview of the major developments and new features will be given. Furthermore, we will present our plans to increase the quality of the re3data entries.

  14. 10 CFR 960.5-2-3 - Meteorology.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... REPOSITORY Preclosure Guidelines Preclosure Radiological Safety § 960.5-2-3 Meteorology. (a) Qualifying condition. The site shall be located such that expected meteorological conditions during repository.... Prevailing meteorological conditions such that any radioactive releases to the atmosphere during repository...

  15. New directions in medical e-curricula and the use of digital repositories.

    PubMed

    Fleiszer, David M; Posel, Nancy H; Steacy, Sean P

    2004-03-01

    Medical educators involved in the growth of multimedia-enhanced e-curricula are increasingly aware of the need for digital repositories to catalogue, store and ensure access to learning objects that are integrated within their online material. The experience at the Faculty of Medicine at McGill University during initial development of a mainstream electronic curriculum reflects this growing recognition that repositories can facilitate the development of a more comprehensive as well as effective electronic curricula. Also, digital repositories can help to ensure efficient utilization of resources through the use, re-use, and reprocessing of multimedia learning, addressing the potential for collaboration among repositories and increasing available material exponentially. The authors review different approaches to the development of a digital repository application, as well as global and specific issues that should be examined in the initial requirements definition and development phase, to ensure current initiatives meet long-term requirements. Often, decisions regarding creation of e-curricula and associated digital repositories are left to interested faculty and their individual development teams. However, the development of an e-curricula and digital repository is not predominantly a technical exercise, but rather one that affects global pedagogical strategies and curricular content and involves a commitment of large-scale resources. Outcomes of these decisions can have long-term consequences and as such, should involve faculty at the highest levels including the dean.

  16. A Prototype Performance Assessment Model for Generic Deep Borehole Repository for High-Level Nuclear Waste - 12132

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lee, Joon H.; Arnold, Bill W.; Swift, Peter N.

    2012-07-01

    A deep borehole repository is one of the four geologic disposal system options currently under study by the U.S. DOE to support the development of a long-term strategy for geologic disposal of commercial used nuclear fuel (UNF) and high-level radioactive waste (HLW). The immediate goal of the generic deep borehole repository study is to develop the necessary modeling tools to evaluate and improve the understanding of the repository system response and processes relevant to long-term disposal of UNF and HLW in a deep borehole. A prototype performance assessment model for a generic deep borehole repository has been developed using themore » approach for a mined geological repository. The preliminary results from the simplified deep borehole generic repository performance assessment indicate that soluble, non-sorbing (or weakly sorbing) fission product radionuclides, such as I-129, Se-79 and Cl-36, are the likely major dose contributors, and that the annual radiation doses to hypothetical future humans associated with those releases may be extremely small. While much work needs to be done to validate the model assumptions and parameters, these preliminary results highlight the importance of a robust seal design in assuring long-term isolation, and suggest that deep boreholes may be a viable alternative to mined repositories for disposal of both HLW and UNF. (authors)« less

  17. 10 CFR 960.5-2-5 - Environmental quality.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... REPOSITORY Preclosure Guidelines Environment, Socioeconomics, and Transportation § 960.5-2-5 Environmental... repository siting, construction, operation, closure, and decommissioning, and projected environmental impacts... of the repository or its support facilities on, a component of the National Park System, the National...

  18. 10 CFR 60.1 - Purpose and scope.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES General..., special nuclear, and byproduct material at a geologic repository operations area sited, constructed, or... at a geologic repository operations area sited, constructed, or operated at Yucca Mountain, Nevada...

  19. 10 CFR 60.31 - Construction authorization.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... REPOSITORIES Licenses Construction Authorization § 60.31 Construction authorization. Upon review and... in a geologic repository operations area of the design proposed without unreasonable risk to the...: (1) DOE has described the proposed geologic repository including but not limited to: (i) The geologic...

  20. 10 CFR 960.5-2-6 - Socioeconomic impacts.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... REPOSITORY Preclosure Guidelines Environment, Socioeconomics, and Transportation § 960.5-2-6 Socioeconomic... and/or economic impacts induced in communities and surrounding regions by repository siting... significant repository-related impacts on community services, housing supply and demand, and the finances of...

  1. 10 CFR 60.15 - Site characterization.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES Licenses... the geologic repository to the extent practical. (2) The number of exploratory boreholes and shafts... characterization. (3) To the extent practical, exploratory boreholes and shafts in the geologic repository...

  2. 10 CFR 960.5-1 - System guidelines.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... REPOSITORY Preclosure Guidelines § 960.5-1 System guidelines. (a) Qualifying conditions—(1) Preclosure... radioactive materials to restricted and unrestricted areas during repository operation and closure shall meet... repository siting, construction, operation, closure, and decommissioning the public and the environment shall...

  3. Uncertainty quantification applied to the radiological characterization of radioactive waste.

    PubMed

    Zaffora, B; Magistris, M; Saporta, G; Chevalier, J-P

    2017-09-01

    This paper describes the process adopted at the European Organization for Nuclear Research (CERN) to quantify uncertainties affecting the characterization of very-low-level radioactive waste. Radioactive waste is a by-product of the operation of high-energy particle accelerators. Radioactive waste must be characterized to ensure its safe disposal in final repositories. Characterizing radioactive waste means establishing the list of radionuclides together with their activities. The estimated activity levels are compared to the limits given by the national authority of the waste disposal. The quantification of the uncertainty affecting the concentration of the radionuclides is therefore essential to estimate the acceptability of the waste in the final repository but also to control the sorting, volume reduction and packaging phases of the characterization process. The characterization method consists of estimating the activity of produced radionuclides either by experimental methods or statistical approaches. The uncertainties are estimated using classical statistical methods and uncertainty propagation. A mixed multivariate random vector is built to generate random input parameters for the activity calculations. The random vector is a robust tool to account for the unknown radiological history of legacy waste. This analytical technique is also particularly useful to generate random chemical compositions of materials when the trace element concentrations are not available or cannot be measured. The methodology was validated using a waste population of legacy copper activated at CERN. The methodology introduced here represents a first approach for the uncertainty quantification (UQ) of the characterization process of waste produced at particle accelerators. Copyright © 2017 Elsevier Ltd. All rights reserved.

  4. A scoping review of online repositories of quality improvement projects, interventions and initiatives in healthcare.

    PubMed

    Bytautas, Jessica P; Gheihman, Galina; Dobrow, Mark J

    2017-04-01

    Quality improvement (QI) is becoming an important focal point for health systems. There is increasing interest among health system stakeholders to learn from and share experiences on the use of QI methods and approaches in their work. Yet there are few easily accessible, online repositories dedicated to documenting QI activity. We conducted a scoping review of publicly available, web-based QI repositories to (i) identify current approaches to sharing information on QI practices; (ii) categorise these approaches based on hosting, scope and size, content acquisition and eligibility, content format and search, and evaluation and engagement characteristics; and (iii) review evaluations of the design, usefulness and impact of their online QI practice repositories. The search strategy consisted of traditional database and grey literature searches, as well as expert consultation, with the ultimate aim of identifying and describing QI repositories of practices undertaken in a healthcare context. We identified 13 QI repositories and found substantial variation across the five categories. The QI repositories used different terminology (eg, practices vs case studies) and approaches to content acquisition, and varied in terms of primary areas of focus. All provided some means for organising content according to categories or themes and most provided at least rudimentary keyword search functionality. Notably, none of the QI repositories included evaluations of their impact. With growing interest in sharing and spreading best practices and increasing reliance on QI as a key contributor to health system performance, the role of QI repositories is likely to expand. Designing future QI repositories based on knowledge of the range and type of features available is an important starting point for improving their usefulness and impact. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  5. Migration of the Gaudi and LHCb software repositories from CVS to Subversion

    NASA Astrophysics Data System (ADS)

    Clemencic, M.; Degaudenzi, H.; LHCb Collaboration

    2011-12-01

    A common code repository is of primary importance in a distributed development environment such as large HEP experiments. CVS (Concurrent Versions System) has been used in the past years at CERN for the hosting of shared software repositories, among which were the repositories for the Gaudi Framework and the LHCb software projects. Many developers around the world produced alternative systems to share code and revisions among several developers, mainly to overcome the limitations in CVS, and CERN has recently started a new service for code hosting based on the version control system Subversion. The differences between CVS and Subversion and the way the code was organized in Gaudi and LHCb CVS repositories required careful study and planning of the migration. Special care was used to define the organization of the new Subversion repository. To avoid as much as possible disruption in the development cycle, the migration has been gradual with the help of tools developed explicitly to hide the differences between the two systems. The principles guiding the migration steps, the organization of the Subversion repository and the tools developed will be presented, as well as the problems encountered both from the librarian and the user points of view.

  6. Decision Tree Repository and Rule Set Based Mingjiang River Estuarine Wetlands Classifaction

    NASA Astrophysics Data System (ADS)

    Zhang, W.; Li, X.; Xiao, W.

    2018-05-01

    The increasing urbanization and industrialization have led to wetland losses in estuarine area of Mingjiang River over past three decades. There has been increasing attention given to produce wetland inventories using remote sensing and GIS technology. Due to inconsistency training site and training sample, traditionally pixel-based image classification methods can't achieve a comparable result within different organizations. Meanwhile, object-oriented image classification technique shows grate potential to solve this problem and Landsat moderate resolution remote sensing images are widely used to fulfill this requirement. Firstly, the standardized atmospheric correct, spectrally high fidelity texture feature enhancement was conducted before implementing the object-oriented wetland classification method in eCognition. Secondly, we performed the multi-scale segmentation procedure, taking the scale, hue, shape, compactness and smoothness of the image into account to get the appropriate parameters, using the top and down region merge algorithm from single pixel level, the optimal texture segmentation scale for different types of features is confirmed. Then, the segmented object is used as the classification unit to calculate the spectral information such as Mean value, Maximum value, Minimum value, Brightness value and the Normalized value. The Area, length, Tightness and the Shape rule of the image object Spatial features and texture features such as Mean, Variance and Entropy of image objects are used as classification features of training samples. Based on the reference images and the sampling points of on-the-spot investigation, typical training samples are selected uniformly and randomly for each type of ground objects. The spectral, texture and spatial characteristics of each type of feature in each feature layer corresponding to the range of values are used to create the decision tree repository. Finally, with the help of high resolution reference images, the random sampling method is used to conduct the field investigation, achieve an overall accuracy of 90.31 %, and the Kappa coefficient is 0.88. The classification method based on decision tree threshold values and rule set developed by the repository, outperforms the results obtained from the traditional methodology. Our decision tree repository and rule set based object-oriented classification technique was an effective method for producing comparable and consistency wetlands data set.

  7. Data Collection, Collaboration, Analysis, and Publication Using the Open Data Repository's (ODR) Data Publisher

    NASA Astrophysics Data System (ADS)

    Lafuente, B.; Stone, N.; Bristow, T.; Keller, R. M.; Blake, D. F.; Downs, R. T.; Pires, A.; Dateo, C. E.; Fonda, M.

    2017-12-01

    In development for nearly four years, the Open Data Repository's (ODR) Data Publisher software has become a useful tool for researchers' data needs. Data Publisher facilitates the creation of customized databases with flexible permission sets that allow researchers to share data collaboratively while improving data discovery and maintaining ownership rights. The open source software provides an end-to-end solution from collection to final repository publication. A web-based interface allows researchers to enter data, view data, and conduct analysis using any programming language supported by JupyterHub (http://www.jupyterhub.org). This toolset makes it possible for a researcher to store and manipulate their data in the cloud from any internet capable device. Data can be embargoed in the system until a date selected by the researcher. For instance, open publication can be set to a date that coincides with publication of data analysis in a third party journal. In conjunction with teams at NASA Ames and the University of Arizona, a number of pilot studies are being conducted to guide the software development so that it allows them to publish and share their data. These pilots include (1) the Astrobiology Habitable Environments Database (AHED), a central searchable repository designed to promote and facilitate the integration and sharing of all the data generated by the diverse disciplines in astrobiology; (2) a database containing the raw and derived data products from the CheMin instrument on the MSL rover Curiosity (http://odr.io/CheMin), featuring a versatile graphing system, instructions and analytical tools to process the data, and a capability to download data in different formats; and (3) the Mineral Evolution project, which by correlating the diversity of mineral species with their ages, localities, and other measurable properties aims to understand how the episodes of planetary accretion and differentiation, plate tectonics, and origin of life lead to a selective evolution of mineral species through changes in temperature, pressure, and composition. Ongoing development will complete integration of third party meta-data standards and publishing data to the semantic web. This project is supported by the Science-Enabling Research Activity (SERA) and NASA NNX11AP82A, MSL.

  8. Comparison of the Environment, Health, And Safety Characteristics of Advanced Thorium- Uranium and Uranium-Plutonium Fuel Cycles

    NASA Astrophysics Data System (ADS)

    Ault, Timothy M.

    The environment, health, and safety properties of thorium-uranium-based (''thorium'') fuel cycles are estimated and compared to those of analogous uranium-plutonium-based (''uranium'') fuel cycle options. A structured assessment methodology for assessing and comparing fuel cycle is refined and applied to several reference fuel cycle options. Resource recovery as a measure of environmental sustainability for thorium is explored in depth in terms of resource availability, chemical processing requirements, and radiological impacts. A review of available experience and recent practices indicates that near-term thorium recovery will occur as a by-product of mining for other commodities, particularly titanium. The characterization of actively-mined global titanium, uranium, rare earth element, and iron deposits reveals that by-product thorium recovery would be sufficient to satisfy even the most intensive nuclear demand for thorium at least six times over. Chemical flowsheet analysis indicates that the consumption of strong acids and bases associated with thorium resource recovery is 3-4 times larger than for uranium recovery, with the comparison of other chemical types being less distinct. Radiologically, thorium recovery imparts about one order of magnitude larger of a collective occupational dose than uranium recovery. Moving to the entire fuel cycle, four fuel cycle options are compared: a limited-recycle (''modified-open'') uranium fuel cycle, a modified-open thorium fuel cycle, a full-recycle (''closed'') uranium fuel cycle, and a closed thorium fuel cycle. A combination of existing data and calculations using SCALE are used to develop material balances for the four fuel cycle options. The fuel cycle options are compared on the bases of resource sustainability, waste management (both low- and high-level waste, including used nuclear fuel), and occupational radiological impacts. At steady-state, occupational doses somewhat favor the closed thorium option while low-level waste volumes slightly favor the closed uranium option, although uncertainties are significant in both cases. The high-level waste properties (radioactivity, decay heat, and ingestion radiotoxicity) all significantly favor the closed fuel cycle options (especially the closed thorium option), but an alternative measure of key fission product inventories that drive risk in a repository slightly favors the uranium fuel cycles due to lower production of iodine-129. Resource requirements are much lower for the closed fuel cycle options and are relatively similar between thorium and uranium. In additional to the steady-state results, a variety of potential transition pathways are considered for both uranium and thorium fuel cycle end-states. For dose, low-level waste, and fission products contributing to repository risk, the differences among transition impacts largely reflected the steady-state differences. However, the HLW properties arrived at a distinctly opposite result in transition (strongly favoring uranium, whereas thorium was strongly favored at steady-state), because used present-day fuel is disposed without being recycled given that uranium-233, rather than plutonium, is the primarily fissile nuclide at the closed thorium fuel cycle's steady-state. Resource consumption was the only metric was strongly influenced by the specific transition pathway selected, favoring those pathways that more quickly arrived at steady-state through higher breeding ratio assumptions regardless of whether thorium or uranium was used.

  9. ROSA P : The National Transportation Library’s Repository and Open Science Access Portal

    DOT National Transportation Integrated Search

    2018-01-01

    The National Transportation Library (NTL) was founded as an all-digital repository of US DOT research reports, technical publications and data products. NTLs primary public offering is ROSA P, the Repository and Open Science Access Portal. An open...

  10. 10 CFR 960.3-3 - Consultation.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... ENERGY GENERAL GUIDELINES FOR THE PRELIMINARY SCREENING OF POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY..., operation, closure, decommissioning, licensing, or regulation of a repository. Written responses to written... purpose of determining the suitability of such area for the development of a repository, the DOE shall...

  11. 10 CFR 60.32 - Conditions of construction authorization.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... GEOLOGIC REPOSITORIES Licenses Construction Authorization § 60.32 Conditions of construction authorization... changes to the features of the geologic repository and the procedures authorized. The restrictions that... setting as well as measures related to the design and construction of the geologic repository operations...

  12. An Automated Acquisition System for Media Exploitation

    DTIC Science & Technology

    2008-06-01

    on the acquisition station, AcqMan will pull out the SHA256 image hash, and the device’s model, serial number, and manufacturer. 2. Query the ADOMEX...Repository Using the data collected above, AcqMan will query the ADOMEX repository. The ADOMEX repository will respond to the query with the SHA256 ’s of...whose SHA256s do not match. The last category will be a list of images that the ADOMEX repository already has and that the acquisition station can

  13. NA-42 TI Shared Software Component Library FY2011 Final Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Knudson, Christa K.; Rutz, Frederick C.; Dorow, Kevin E.

    The NA-42 TI program initiated an effort in FY2010 to standardize its software development efforts with the long term goal of migrating toward a software management approach that will allow for the sharing and reuse of code developed within the TI program, improve integration, ensure a level of software documentation, and reduce development costs. The Pacific Northwest National Laboratory (PNNL) has been tasked with two activities that support this mission. PNNL has been tasked with the identification, selection, and implementation of a Shared Software Component Library. The intent of the library is to provide a common repository that is accessiblemore » by all authorized NA-42 software development teams. The repository facilitates software reuse through a searchable and easy to use web based interface. As software is submitted to the repository, the component registration process captures meta-data and provides version control for compiled libraries, documentation, and source code. This meta-data is then available for retrieval and review as part of library search results. In FY2010, PNNL and staff from the Remote Sensing Laboratory (RSL) teamed up to develop a software application with the goal of replacing the aging Aerial Measuring System (AMS). The application under development includes an Advanced Visualization and Integration of Data (AVID) framework and associated AMS modules. Throughout development, PNNL and RSL have utilized a common AMS code repository for collaborative code development. The AMS repository is hosted by PNNL, is restricted to the project development team, is accessed via two different geographic locations and continues to be used. The knowledge gained from the collaboration and hosting of this repository in conjunction with PNNL software development and systems engineering capabilities were used in the selection of a package to be used in the implementation of the software component library on behalf of NA-42 TI. The second task managed by PNNL is the development and continued maintenance of the NA-42 TI Software Development Questionnaire. This questionnaire is intended to help software development teams working under NA-42 TI in documenting their development activities. When sufficiently completed, the questionnaire illustrates that the software development activities recorded incorporate significant aspects of the software engineering lifecycle. The questionnaire template is updated as comments are received from NA-42 and/or its development teams and revised versions distributed to those using the questionnaire. PNNL also maintains a list of questionnaire recipients. The blank questionnaire template, the AVID and AMS software being developed, and the completed AVID AMS specific questionnaire are being used as the initial content to be established in the TI Component Library. This report summarizes the approach taken to identify requirements, search for and evaluate technologies, and the approach taken for installation of the software needed to host the component library. Additionally, it defines the process by which users request access for the contribution and retrieval of library content.« less

  14. 10 CFR 960.4 - Postclosure guidelines.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... REPOSITORY Postclosure Guidelines § 960.4 Postclosure guidelines. The guidelines in this subpart specify the factors to be considered in evaluating and comparing sites on the basis of expected repository performance... NRC and EPA regulations. These requirements must be met by the repository system, which contains...

  15. 10 CFR 60.3 - License required.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES General... byproduct material at a geologic repository operations area except as authorized by a license issued by the Commission pursuant to this part. (b) DOE shall not commence construction of a geologic repository operations...

  16. Asset Reuse of Images from a Repository

    ERIC Educational Resources Information Center

    Herman, Deirdre

    2014-01-01

    According to Markus's theory of reuse, when digital repositories are deployed to collect and distribute organizational assets, they supposedly help ensure accountability, extend information exchange, and improve productivity. Such repositories require a large investment due to the continuing costs of hardware, software, user licenses, training,…

  17. 10 CFR 60.17 - Contents of site characterization plan.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... GEOLOGIC REPOSITORIES Licenses Preapplication Review § 60.17 Contents of site characterization plan. The... construction authorization for a geologic repository operations area; (4) Criteria, developed pursuant to... area for the location of a geologic repository; and (5) Any other information which the Commission, by...

  18. 10 CFR 960.4-2-2 - Geochemistry.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... REPOSITORY Postclosure Guidelines § 960.4-2-2 Geochemistry. (a) Qualifying condition. The present and... future, not affect or would favorably affect the ability of the geologic repository to isolate the waste... subjected to expected repository conditions, would remain unaltered or would alter to mineral assemblages...

  19. 17 CFR 49.3 - Procedures for registration.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... if the Commission finds that such swap data repository is appropriately organized, and has the...) SWAP DATA REPOSITORIES § 49.3 Procedures for registration. (a) Application procedures. (1) An applicant, person or entity desiring to be registered as a swap data repository shall file electronically an...

  20. Biological Web Service Repositories Review.

    PubMed

    Urdidiales-Nieto, David; Navas-Delgado, Ismael; Aldana-Montes, José F

    2017-05-01

    Web services play a key role in bioinformatics enabling the integration of database access and analysis of algorithms. However, Web service repositories do not usually publish information on the changes made to their registered Web services. Dynamism is directly related to the changes in the repositories (services registered or unregistered) and at service level (annotation changes). Thus, users, software clients or workflow based approaches lack enough relevant information to decide when they should review or re-execute a Web service or workflow to get updated or improved results. The dynamism of the repository could be a measure for workflow developers to re-check service availability and annotation changes in the services of interest to them. This paper presents a review on the most well-known Web service repositories in the life sciences including an analysis of their dynamism. Freshness is introduced in this paper, and has been used as the measure for the dynamism of these repositories. © 2017 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA.

  1. Finding relevant biomedical datasets: the UC San Diego solution for the bioCADDIE Retrieval Challenge

    PubMed Central

    Wei, Wei; Ji, Zhanglong; He, Yupeng; Zhang, Kai; Ha, Yuanchi; Li, Qi; Ohno-Machado, Lucila

    2018-01-01

    Abstract The number and diversity of biomedical datasets grew rapidly in the last decade. A large number of datasets are stored in various repositories, with different formats. Existing dataset retrieval systems lack the capability of cross-repository search. As a result, users spend time searching datasets in known repositories, and they typically do not find new repositories. The biomedical and healthcare data discovery index ecosystem (bioCADDIE) team organized a challenge to solicit new indexing and searching strategies for retrieving biomedical datasets across repositories. We describe the work of one team that built a retrieval pipeline and examined its performance. The pipeline used online resources to supplement dataset metadata, automatically generated queries from users’ free-text questions, produced high-quality retrieval results and achieved the highest inferred Normalized Discounted Cumulative Gain among competitors. The results showed that it is a promising solution for cross-database, cross-domain and cross-repository biomedical dataset retrieval. Database URL: https://github.com/w2wei/dataset_retrieval_pipeline PMID:29688374

  2. Batch sorption results for neptunium transport through Yucca Mountain tuffs. Yucca Mountain Site Characterization Program milestone 3349

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Triay, I.R.; Cotter, C.R.; Huddleston, M.H.

    1996-09-01

    We studied the sorption of neptunium onto tuffs characteristic of the proposed nuclear waste repository at Yucca Mountain, Nevada. The neptunium was in the Np(V) oxidation state under oxidizing conditions in groundwaters from two wells located close to the repository site (J-13 and UE-25 p No.1). We used devitrified, vitric, zeolitic (with emphasis on clinoptilolite-rich samples), and calcite-rich tuffs characteristic of the geology of the site. Neptunium sorbed well onto calcite and calcite-rich tuffs, indicating that a significant amount of neptunium retardation can be expected under fractured-flow scenarios because of calcite coating of the fractures. Neptunium sorption onto clinoptilolite-rich zeoliticmore » tuffs in J-13 well water (pH from 7 to 8.5) was moderate, increased with decreasing pH, and correlated to surface area and amount of clinoptilolite. Neptunium sorbed poorly onto zeolitic tuffs from UE-25 p No.1 groundwater (pH from 7 to 9) and onto devitrified and vitric tuffs from J-13 and UE-25 p No.1 waters (pH from 7 to 9). Iron oxides appeared to be passivated in tuffs, not seeming to contribute to the observed neptunium sorption, even though neptunium sorption onto synthetic iron oxide is significant.« less

  3. Climate Data Analytics Workflow Management

    NASA Astrophysics Data System (ADS)

    Zhang, J.; Lee, S.; Pan, L.; Mattmann, C. A.; Lee, T. J.

    2016-12-01

    In this project we aim to pave a novel path to create a sustainable building block toward Earth science big data analytics and knowledge sharing. Closely studying how Earth scientists conduct data analytics research in their daily work, we have developed a provenance model to record their activities, and to develop a technology to automatically generate workflows for scientists from the provenance. On top of it, we have built the prototype of a data-centric provenance repository, and establish a PDSW (People, Data, Service, Workflow) knowledge network to support workflow recommendation. To ensure the scalability and performance of the expected recommendation system, we have leveraged the Apache OODT system technology. The community-approved, metrics-based performance evaluation web-service will allow a user to select a metric from the list of several community-approved metrics and to evaluate model performance using the metric as well as the reference dataset. This service will facilitate the use of reference datasets that are generated in support of the model-data intercomparison projects such as Obs4MIPs and Ana4MIPs. The data-centric repository infrastructure will allow us to catch richer provenance to further facilitate knowledge sharing and scientific collaboration in the Earth science community. This project is part of Apache incubator CMDA project.

  4. Using Object Storage Technology vs Vendor Neutral Archives for an Image Data Repository Infrastructure.

    PubMed

    Bialecki, Brian; Park, James; Tilkin, Mike

    2016-08-01

    The intent of this project was to use object storage and its database, which has the ability to add custom extensible metadata to an imaging object being stored within the system, to harness the power of its search capabilities, and to close the technology gap that healthcare faces. This creates a non-disruptive tool that can be used natively by both legacy systems and the healthcare systems of today which leverage more advanced storage technologies. The base infrastructure can be populated alongside current workflows without any interruption to the delivery of services. In certain use cases, this technology can be seen as a true alternative to the VNA (Vendor Neutral Archive) systems implemented by healthcare today. The scalability, security, and ability to process complex objects makes this more than just storage for image data and a commodity to be consumed by PACS (Picture Archiving and Communication System) and workstations. Object storage is a smart technology that can be leveraged to create vendor independence, standards compliance, and a data repository that can be mined for truly relevant content by adding additional context to search capabilities. This functionality can lead to efficiencies in workflow and a wealth of minable data to improve outcomes into the future.

  5. An Introduction to SPEAR (Seismogram Picking Error from Analyst Review)

    NASA Astrophysics Data System (ADS)

    Zeiler, C. P.; Velasco, A. A.; Anderson, D.; Pingitore, N. E.

    2008-12-01

    A grassroots initiative began in February of 2008 at the University of Texas at El Paso to understand how seismologists measure earthquakes. The Seismogram Picking Error from Analyst Review (SPEAR) project is designed to be a forum where seismologists can propose, discuss and experimentally test theories on proper procedures to identify and measure seismic phases. We outline the history of seismogram analysis and explore areas of seismogram analysis that still need to be defined. The main concern for SPEAR, at this time, is the impact of picking errors produced by merging earthquake catalogs. Our initial effort has been to establish a common data set for seismologists to pick. The preliminary studies from this data set have shown that significant bias between authors of catalogs may exist. We provide techniques to ensure that these biases can be identified and correctly managed to provide accurate mergers of earthquake measurements. The overall goal of SPEAR is to provide a repository of information to aid seismologists in comparing and sharing measurements. We want to document in the repository and explore all aspects of the picking process, from the basics of learning how to read a seismogram to complex transformations and enhancements of signals. Your participation in SPEAR will aid the seismological community to close the knowledge gaps that exist in seismogram analysis.

  6. Collaborative Information Retrieval Method among Personal Repositories

    NASA Astrophysics Data System (ADS)

    Kamei, Koji; Yukawa, Takashi; Yoshida, Sen; Kuwabara, Kazuhiro

    In this paper, we describe a collaborative information retrieval method among personal repositorie and an implementation of the method on a personal agent framework. We propose a framework for personal agents that aims to enable the sharing and exchange of information resources that are distributed unevenly among individuals. The kernel of a personal agent framework is an RDF(resource description framework)-based information repository for storing, retrieving and manipulating privately collected information, such as documents the user read and/or wrote, email he/she exchanged, web pages he/she browsed, etc. The repository also collects annotations to information resources that describe relationships among information resources and records of interaction between the user and information resources. Since the information resources in a personal repository and their structure are personalized, information retrieval from other users' is an important application of the personal agent. A vector space model with a personalized concept-base is employed as an information retrieval mechanism in a personal repository. Since a personalized concept-base is constructed from information resources in a personal repository, it reflects its user's knowledge and interests. On the other hand, it leads to another problem while querying other users' personal repositories; that is, simply transferring query requests does not provide desirable results. To solve this problem, we propose a query equalization scheme based on a relevance feedback method for collaborative information retrieval between personalized concept-bases. In this paper, we describe an implementation of the collaborative information retrieval method and its user interface on the personal agent framework.

  7. Organizing Scientific Data Sets: Studying Similarities and Differences in Metadata and Subject Term Creation

    ERIC Educational Resources Information Center

    White, Hollie C.

    2012-01-01

    Background: According to Salo (2010), the metadata entered into repositories are "disorganized" and metadata schemes underlying repositories are "arcane". This creates a challenging repository environment in regards to personal information management (PIM) and knowledge organization systems (KOSs). This dissertation research is…

  8. Worth the Work

    ERIC Educational Resources Information Center

    Schaffhauser, Dian

    2010-01-01

    Even in the age of Google, digital repositories can add tremendous value to an institution. Yet creating and maintaining these collections is no small task. Digital repository advocates will concede that the challenges in building and maintaining these collections can daunt even the most intrepid supporters. Three repository directors share their…

  9. Collaboration Nation: The Building of the Welsh Repository Network

    ERIC Educational Resources Information Center

    Knowles, Jacqueline

    2010-01-01

    Purpose: The purpose of this paper is to disseminate information about the Welsh Repository Network (WRN), innovative work being undertaken to build an integrated network of institutional digital repositories. A collaborative approach, in particular through the provision of centralised technical and organisational support, has demonstrated…

  10. 76 FR 81950 - Privacy Act; System of Records

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-29

    ... ``Consolidated Data Repository'' (09-90-1000). This system of records is being amended to include records... Repository'' (SORN 09-90-1000). OIG is adding record sources to the system. This system fulfills our..., and investigations of the Medicare and Medicaid programs. SYSTEM NAME: Consolidated Data Repository...

  11. 10 CFR 60.22 - Filing and distribution of application.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... GEOLOGIC REPOSITORIES Licenses License Applications § 60.22 Filing and distribution of application. (a) An application for a construction authorization for a high-level radioactive waste repository at a geologic repository operations area, and an application for a license to receive and possess source, special nuclear...

  12. 10 CFR 960.4-2-5 - Erosion.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... ENERGY GENERAL GUIDELINES FOR THE PRELIMINARY SCREENING OF POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY... exhumation would not be expected to occur during the first one million years after repository closure. (c... the ability of the geologic repository to isolate the waste. (d) Disqualifying condition. The site...

  13. 10 CFR 960.3-2 - Siting process.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... REPOSITORY Implementation Guidelines § 960.3-2 Siting process. The siting process begins with site screening... first repository before the enactment of the Act, and the identification of such sites was made after... identification of potentially acceptable sites for the second and subsequent repositories shall be conducted in...

  14. 76 FR 14057 - Notice of Inventory Completion: University of Wyoming, Anthropology Department, Human Remains...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-15

    ...: University of Wyoming, Anthropology Department, Human Remains Repository, Laramie, WY AGENCY: National Park... Anthropology Department, Human Remains Repository, Laramie, WY. The human remains and associated funerary... the human remains was made by University of Wyoming, Anthropology Department, Human Remains Repository...

  15. TRAC Searchable Research Library

    DTIC Science & Technology

    2016-05-01

    network accessible document repository for technical documents and similar document artifacts. We used a model-based approach using the Vector...demonstration and model refinement. 14. SUBJECT TERMS Knowledge Management, Document Repository , Digital Library, Vector Directional Data Model...27 Figure D1. Administrator Repository Upload Page. ................................................................... D-2 Figure D2

  16. 10 CFR 960.5-2-4 - Offsite installations and operations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... SITES FOR A NUCLEAR WASTE REPOSITORY Preclosure Guidelines Preclosure Radiological Safety § 960.5-2-4... operations, including atomic energy defense activities, (1) will not significantly affect repository siting...), when considered together with emissions from repository operation and closure, will not be likely to...

  17. Microsoft Repository Version 2 and the Open Information Model.

    ERIC Educational Resources Information Center

    Bernstein, Philip A.; Bergstraesser, Thomas; Carlson, Jason; Pal, Shankar; Sanders, Paul; Shutt, David

    1999-01-01

    Describes the programming interface and implementation of the repository engine and the Open Information Model for Microsoft Repository, an object-oriented meta-data management facility that ships in Microsoft Visual Studio and Microsoft SQL Server. Discusses Microsoft's component object model, object manipulation, queries, and information…

  18. 10 CFR 2.1027 - Sua sponte.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Applicable to Proceedings for the Issuance of Licenses for the Receipt of High-Level Radioactive Waste at a... construction authorization for a high-level radioactive waste repository at a geologic repository operations...-level radioactive waste at a geologic repository operations area under parts 60 or 63 of this chapter...

  19. A comparative study of discrete fracture network and equivalent continuum models for simulating flow and transport in the far field of a hypothetical nuclear waste repository in crystalline host rock

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hadgu, Teklu; Karra, Satish; Kalinina, Elena

    One of the major challenges of simulating flow and transport in the far field of a geologic repository in crystalline host rock is related to reproducing the properties of the fracture network over the large volume of rock with sparse fracture characterization data. Various approaches have been developed to simulate flow and transport through the fractured rock. The approaches can be broadly divided into Discrete Fracture Network (DFN) and Equivalent Continuum Model (ECM). The DFN explicitly represents individual fractures, while the ECM uses fracture properties to determine equivalent continuum parameters. In this paper, we compare DFN and ECM in termsmore » of upscaled observed transport properties through generic fracture networks. The major effort was directed on making the DFN and ECM approaches similar in their conceptual representations. This allows for separating differences related to the interpretation of the test conditions and parameters from the differences between the DFN and ECM approaches. The two models are compared using a benchmark test problem that is constructed to represent the far field (1 × 1 × 1 km 3) of a hypothetical repository in fractured crystalline rock. The test problem setting uses generic fracture properties that can be expected in crystalline rocks. The models are compared in terms of the: 1) effective permeability of the domain, and 2) nonreactive solute breakthrough curves through the domain. The principal differences between the models are mesh size, network connectivity, matrix diffusion and anisotropy. We demonstrate how these differences affect the flow and transport. Finally, we identify the factors that should be taken in consideration when selecting an approach most suitable for the site-specific conditions.« less

  20. A comparative study of discrete fracture network and equivalent continuum models for simulating flow and transport in the far field of a hypothetical nuclear waste repository in crystalline host rock

    DOE PAGES

    Hadgu, Teklu; Karra, Satish; Kalinina, Elena; ...

    2017-07-28

    One of the major challenges of simulating flow and transport in the far field of a geologic repository in crystalline host rock is related to reproducing the properties of the fracture network over the large volume of rock with sparse fracture characterization data. Various approaches have been developed to simulate flow and transport through the fractured rock. The approaches can be broadly divided into Discrete Fracture Network (DFN) and Equivalent Continuum Model (ECM). The DFN explicitly represents individual fractures, while the ECM uses fracture properties to determine equivalent continuum parameters. In this paper, we compare DFN and ECM in termsmore » of upscaled observed transport properties through generic fracture networks. The major effort was directed on making the DFN and ECM approaches similar in their conceptual representations. This allows for separating differences related to the interpretation of the test conditions and parameters from the differences between the DFN and ECM approaches. The two models are compared using a benchmark test problem that is constructed to represent the far field (1 × 1 × 1 km 3) of a hypothetical repository in fractured crystalline rock. The test problem setting uses generic fracture properties that can be expected in crystalline rocks. The models are compared in terms of the: 1) effective permeability of the domain, and 2) nonreactive solute breakthrough curves through the domain. The principal differences between the models are mesh size, network connectivity, matrix diffusion and anisotropy. We demonstrate how these differences affect the flow and transport. Finally, we identify the factors that should be taken in consideration when selecting an approach most suitable for the site-specific conditions.« less

  1. Characterize Eruptive Processes at Yucca Mountain, Nevada

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    G. Valentine

    2001-12-20

    This Analysis/Model Report (AMR), ''Characterize Eruptive Processes at Yucca Mountain, Nevada'', presents information about natural volcanic systems and the parameters that can be used to model their behavior. This information is used to develop parameter-value distributions appropriate for analysis of the consequences of volcanic eruptions through a potential repository at Yucca Mountain. Many aspects of this work are aimed at resolution of the Igneous Activity Key Technical Issue (KTI) as identified by the Nuclear Regulatory Commission (NRC 1998, p. 3), Subissues 1 and 2, which address the probability and consequence of igneous activity at the proposed repository site, respectively. Withinmore » the framework of the Disruptive Events Process Model Report (PMR), this AMR provides information for the calculations in two other AMRs ; parameters described herein are directly used in calculations in these reports and will be used in Total System Performance Assessment (TSPA). Compilation of this AMR was conducted as defined in the Development Plan, except as noted. The report begins with considerations of the geometry of volcanic feeder systems, which are of primary importance in predicting how much of a potential repository would be affected by an eruption. This discussion is followed by one of the physical and chemical properties of the magmas, which influences both eruptive styles and mechanisms for interaction with radioactive waste packages. Eruptive processes including the ascent velocity of magma at depth, the onset of bubble nucleation and growth in the rising magmas, magma fragmentation, and velocity of the resulting gas-particle mixture are then discussed. The duration of eruptions, their power output, and mass discharge rates are also described. The next section summarizes geologic constraints regarding the interaction between magma and waste packages. Finally, they discuss bulk grain size produced by relevant explosive eruptions and grain shapes.« less

  2. NATIONAL GEOSCIENCE DATA REPOSITORY SYSTEM PHASE III: IMPLEMENTATION AND OPERATION OF THE REPOSITORY

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Marcus Milling

    2003-04-01

    The NGDRS has facilitated 85% of cores, cuttings, and other data identified available for transfer to the public sector. Over 12 million linear feet of cores and cuttings, in addition to large numbers of paleontological samples and are now available for public use. To date, with industry contributions for program operations and data transfers, the NGDRS project has realized a 6.5 to 1 return on investment to Department of Energy funds. Large-scale transfers of seismic data have been evaluated, but based on the recommendation of the NGDRS steering committee, cores have been given priority because of the vast scale ofmore » the seismic data problem relative to the available funding. The rapidly changing industry conditions have required that the primary core and cuttings preservation strategy evolve as well. Additionally, the NGDRS clearinghouse is evaluating the viability of transferring seismic data covering the western shelf of the Florida Gulf Coast. AGI remains actively involved in working to realize the vision of the National Research Council's report of geoscience data preservation. GeoTrek has been ported to Linux and MySQL, ensuring a purely open-source version of the software. This effort is key in ensuring long-term viability of the software so that is can continue basic operation regardless of specific funding levels. Work has commenced on a major revision of GeoTrek, using the open-source MapServer project and its related MapScript language. This effort will address a number of key technology issues that appear to be rising for 2002, including the discontinuation of the use of Java in future Microsoft operating systems. Discussions have been held regarding establishing potential new public data repositories, with hope for final determination in 2002.« less

  3. NATIONAL GEOSCIENCE DATA REPOSITORY SYSTEM PHASE III: IMPLEMENTATION AND OPERATION OF THE REPOSITORY

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Marcus Milling

    2002-10-01

    The NGDRS has facilitated 85% of cores, cuttings, and other data identified available for transfer to the public sector. Over 12 million linear feet of cores and cuttings, in addition to large numbers of paleontological samples and are now available for public use. To date, with industry contributions for program operations and data transfers, the NGDRS project has realized a 6.5 to 1 return on investment to Department of Energy funds. Large-scale transfers of seismic data have been evaluated, but based on the recommendation of the NGDRS steering committee, cores have been given priority because of the vast scale ofmore » the seismic data problem relative to the available funding. The rapidly changing industry conditions have required that the primary core and cuttings preservation strategy evolve as well. Additionally, the NGDRS clearinghouse is evaluating the viability of transferring seismic data covering the western shelf of the Florida Gulf Coast. AGI remains actively involved in working to realize the vision of the National Research Council's report of geoscience data preservation. GeoTrek has been ported to Linux and MySQL, ensuring a purely open-source version of the software. This effort is key in ensuring long-term viability of the software so that is can continue basic operation regardless of specific funding levels. Work has commenced on a major revision of GeoTrek, using the open-source MapServer project and its related MapScript language. This effort will address a number of key technology issues that appear to be rising for 2002, including the discontinuation of the use of Java in future Microsoft operating systems. Discussions have been held regarding establishing potential new public data repositories, with hope for final determination in 2002.« less

  4. Canadian Open Genetics Repository (COGR): a unified clinical genomics database as a community resource for standardising and sharing genetic interpretations.

    PubMed

    Lerner-Ellis, Jordan; Wang, Marina; White, Shana; Lebo, Matthew S

    2015-07-01

    The Canadian Open Genetics Repository is a collaborative effort for the collection, storage, sharing and robust analysis of variants reported by medical diagnostics laboratories across Canada. As clinical laboratories adopt modern genomics technologies, the need for this type of collaborative framework is increasingly important. A survey to assess existing protocols for variant classification and reporting was delivered to clinical genetics laboratories across Canada. Based on feedback from this survey, a variant assessment tool was made available to all laboratories. Each participating laboratory was provided with an instance of GeneInsight, a software featuring versioning and approval processes for variant assessments and interpretations and allowing for variant data to be shared between instances. Guidelines were established for sharing data among clinical laboratories and in the final outreach phase, data will be made readily available to patient advocacy groups for general use. The survey demonstrated the need for improved standardisation and data sharing across the country. A variant assessment template was made available to the community to aid with standardisation. Instances of the GeneInsight tool were provided to clinical diagnostic laboratories across Canada for the purpose of uploading, transferring, accessing and sharing variant data. As an ongoing endeavour and a permanent resource, the Canadian Open Genetics Repository aims to serve as a focal point for the collaboration of Canadian laboratories with other countries in the development of tools that take full advantage of laboratory data in diagnosing, managing and treating genetic diseases. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  5. The real-time fMRI neurofeedback based stratification of Default Network Regulation Neuroimaging data repository.

    PubMed

    McDonald, Amalia R; Muraskin, Jordan; Dam, Nicholas T Van; Froehlich, Caroline; Puccio, Benjamin; Pellman, John; Bauer, Clemens C C; Akeyson, Alexis; Breland, Melissa M; Calhoun, Vince D; Carter, Steven; Chang, Tiffany P; Gessner, Chelsea; Gianonne, Alyssa; Giavasis, Steven; Glass, Jamie; Homann, Steven; King, Margaret; Kramer, Melissa; Landis, Drew; Lieval, Alexis; Lisinski, Jonathan; Mackay-Brandt, Anna; Miller, Brittny; Panek, Laura; Reed, Hayley; Santiago, Christine; Schoell, Eszter; Sinnig, Richard; Sital, Melissa; Taverna, Elise; Tobe, Russell; Trautman, Kristin; Varghese, Betty; Walden, Lauren; Wang, Runtang; Waters, Abigail B; Wood, Dylan C; Castellanos, F Xavier; Leventhal, Bennett; Colcombe, Stanley J; LaConte, Stephen; Milham, Michael P; Craddock, R Cameron

    2017-02-01

    This data descriptor describes a repository of openly shared data from an experiment to assess inter-individual differences in default mode network (DMN) activity. This repository includes cross-sectional functional magnetic resonance imaging (fMRI) data from the Multi Source Interference Task, to assess DMN deactivation, the Moral Dilemma Task, to assess DMN activation, a resting state fMRI scan, and a DMN neurofeedback paradigm, to assess DMN modulation, along with accompanying behavioral and cognitive measures. We report technical validation from n=125 participants of the final targeted sample of 180 participants. Each session includes acquisition of one whole-brain anatomical scan and whole-brain echo-planar imaging (EPI) scans, acquired during the aforementioned tasks and resting state. The data includes several self-report measures related to perseverative thinking, emotion regulation, and imaginative processes, along with a behavioral measure of rapid visual information processing. Technical validation of the data confirms that the tasks deactivate and activate the DMN as expected. Group level analysis of the neurofeedback data indicates that the participants are able to modulate their DMN with considerable inter-subject variability. Preliminary analysis of behavioral responses and specifically self-reported sleep indicate that as many as 73 participants may need to be excluded from an analysis depending on the hypothesis being tested. The present data are linked to the enhanced Nathan Kline Institute, Rockland Sample and builds on the comprehensive neuroimaging and deep phenotyping available therein. As limited information is presently available about individual differences in the capacity to directly modulate the default mode network, these data provide a unique opportunity to examine DMN modulation ability in relation to numerous phenotypic characteristics. Copyright © 2016 Elsevier Inc. All rights reserved.

  6. Raising orphans from a metadata morass: A researcher's guide to re-use of public 'omics data.

    PubMed

    Bhandary, Priyanka; Seetharam, Arun S; Arendsee, Zebulun W; Hur, Manhoi; Wurtele, Eve Syrkin

    2018-02-01

    More than 15 petabases of raw RNAseq data is now accessible through public repositories. Acquisition of other 'omics data types is expanding, though most lack a centralized archival repository. Data-reuse provides tremendous opportunity to extract new knowledge from existing experiments, and offers a unique opportunity for robust, multi-'omics analyses by merging metadata (information about experimental design, biological samples, protocols) and data from multiple experiments. We illustrate how predictive research can be accelerated by meta-analysis with a study of orphan (species-specific) genes. Computational predictions are critical to infer orphan function because their coding sequences provide very few clues. The metadata in public databases is often confusing; a test case with Zea mays mRNA seq data reveals a high proportion of missing, misleading or incomplete metadata. This metadata morass significantly diminishes the insight that can be extracted from these data. We provide tips for data submitters and users, including specific recommendations to improve metadata quality by more use of controlled vocabulary and by metadata reviews. Finally, we advocate for a unified, straightforward metadata submission and retrieval system. Copyright © 2017 Elsevier B.V. All rights reserved.

  7. ETHNOS: A versatile electronic tool for the development and curation of national genetic databases

    PubMed Central

    2010-01-01

    National and ethnic mutation databases (NEMDBs) are emerging online repositories, recording extensive information about the described genetic heterogeneity of an ethnic group or population. These resources facilitate the provision of genetic services and provide a comprehensive list of genomic variations among different populations. As such, they enhance awareness of the various genetic disorders. Here, we describe the features of the ETHNOS software, a simple but versatile tool based on a flat-file database that is specifically designed for the development and curation of NEMDBs. ETHNOS is a freely available software which runs more than half of the NEMDBs currently available. Given the emerging need for NEMDB in genetic testing services and the fact that ETHNOS is the only off-the-shelf software available for NEMDB development and curation, its adoption in subsequent NEMDB development would contribute towards data content uniformity, unlike the diverse contents and quality of the available gene (locus)-specific databases. Finally, we allude to the potential applications of NEMDBs, not only as worldwide central allele frequency repositories, but also, and most importantly, as data warehouses of individual-level genomic data, hence allowing for a comprehensive ethnicity-specific documentation of genomic variation. PMID:20650823

  8. ETHNOS : A versatile electronic tool for the development and curation of national genetic databases.

    PubMed

    van Baal, Sjozef; Zlotogora, Joël; Lagoumintzis, George; Gkantouna, Vassiliki; Tzimas, Ioannis; Poulas, Konstantinos; Tsakalidis, Athanassios; Romeo, Giovanni; Patrinos, George P

    2010-06-01

    National and ethnic mutation databases (NEMDBs) are emerging online repositories, recording extensive information about the described genetic heterogeneity of an ethnic group or population. These resources facilitate the provision of genetic services and provide a comprehensive list of genomic variations among different populations. As such, they enhance awareness of the various genetic disorders. Here, we describe the features of the ETHNOS software, a simple but versatile tool based on a flat-file database that is specifically designed for the development and curation of NEMDBs. ETHNOS is a freely available software which runs more than half of the NEMDBs currently available. Given the emerging need for NEMDB in genetic testing services and the fact that ETHNOS is the only off-the-shelf software available for NEMDB development and curation, its adoption in subsequent NEMDB development would contribute towards data content uniformity, unlike the diverse contents and quality of the available gene (locus)-specific databases. Finally, we allude to the potential applications of NEMDBs, not only as worldwide central allele frequency repositories, but also, and most importantly, as data warehouses of individual-level genomic data, hence allowing for a comprehensive ethnicity-specific documentation of genomic variation.

  9. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Barr, G.E.; Borns, D.J.; Fridrich, C.

    A comprehensive collection of scenarios is presented that connect initiating tectonic events with radionuclide releases by logical and physically possible combinations or sequences of features, events and processes. The initiating tectonic events include both discrete faulting and distributed rock deformation developed through the repository and adjacent to it, as well as earthquake-induced ground motion and changes in tectonic stress at the site. The effects of these tectonic events include impacts on the engineered-barrier system, such as container rupture and failure of repository tunnels. These effects also include a wide range of hydrologic effects such as changes in pathways and flowmore » rates in the unsaturated and saturated zones, changes in the water-table configuration, and in the development of perched-water systems. These scenarios are intended go guide performance-assessment analyses and to assist principal investigators in how essential field, laboratory, and calculational studies are used. This suite of scenarios will help ensure that all important aspects of the system disturbance related to a tectonic scenario are captured in numerical analyses. It also provides a record of all options considered by project analysts to provide documentation required for licensing agreement. The final portion of this report discusses issues remaining to be addressed with respect to tectonic activity. 105 refs.« less

  10. Radioactively contaminated electric arc furnace dust as an addition to the immobilization mortar in low- and medium-activity repositories.

    PubMed

    Castellote, Marta; Menéndez, Esperanza; Andrade, Carmen; Zuloaga, Pablo; Navarro, Mariano; Ordóñez, Manuel

    2004-05-15

    Electric arc furnace dust (EAFD), generated by the steel-making industry, is in itself an intrinsic hazardous waste; however, the case may also be that scrap used in the process is accidentally contaminated by radioactive elements such as cesium. In this case the resulting EAFD is to be handled as radioactive waste, being duly confined in low- and medium-activity repositories (LMAR). What this paper studies is the reliability of using this radioactive EAFD as an addition in the immobilization mortar of the containers of the LMAR, that is, from the point of view of the durability. Different mixes of mortar containing different percentages of EAFD have been subjected to flexural and compressive strength, initial and final setting time, XRD study, total porosity and pore size distribution, determination of the chloride diffusion coefficient, dimensional stability tests, hydration heat, workability of the fresh mix, and leaching behavior. What is deduced from the results is that for the conditions used in this research, (cement + sand) can be replaced by EAFD upto a ratio [EAFD/(cement + EAFD)] of 46% in the immobilization mortar of LMAR, apparently without any loss in the long-term durability properties of the mortar.

  11. Science, institutional archives and open access: an overview and a pilot survey on the Italian cancer research institutions.

    PubMed

    Poltronieri, Elisabetta; Truccolo, Ivana; Di Benedetto, Corrado; Castelli, Mauro; Mazzocut, Mauro; Cognetti, Gaetana

    2010-12-20

    The Open Archive Initiative (OAI) refers to a movement started around the '90 s to guarantee free access to scientific information by removing the barriers to research results, especially those related to the ever increasing journal subscription prices. This new paradigm has reshaped the scholarly communication system and is closely connected to the build up of institutional repositories (IRs) conceived to the benefit of scientists and research bodies as a means to keep possession of their own literary production. The IRs are high-value tools which permit authors to gain visibility by enabling rapid access to scientific material (not only publications) thus increasing impact (citation rate) and permitting a multidimensional assessment of research findings. A survey was conducted in March 2010 to mainly explore the managing system in use for archiving the research finding adopted by the Italian Scientific Institutes for Research, Hospitalization and Health Care (IRCCS) of the oncology area within the Italian National Health Service (Servizio Sanitario Nazionale, SSN). They were asked to respond to a questionnaire intended to collect data about institutional archives, metadata formats and posting of full-text documents. The enquiry concerned also the perceived role of the institutional repository DSpace ISS, built up by the Istituto Superiore di Sanità (ISS) and based on a XML scheme for encoding metadata. Such a repository aims at acting as a unique reference point for the biomedical information produced by the Italian research institutions. An in-depth analysis has also been performed on the collection of information material addressed to patients produced by the institutions surveyed. The survey respondents were 6 out of 9. The results reveal the use of different practices and standard among the institutions concerning: the type of documentation collected, the software adopted, the use and format of metadata and the conditions of accessibility to the IRs. The Italian research institutions in the field of oncology are moving the first steps towards the philosophy of OA. The main effort should be the implementation of common procedures also in order to connect scientific publications to researchers curricula. In this framework, an important effort is represented by the project of ISS aimed to set a common interface able to allow migration of data from partner institutions to the OA compliant repository DSpace ISS.

  12. Effects of Heat Generation on Nuclear Waste Disposal in Salt

    NASA Astrophysics Data System (ADS)

    Clayton, D. J.

    2008-12-01

    Disposal of nuclear waste in salt is an established technology, as evidenced by the successful operations of the Waste Isolation Pilot Plant (WIPP) since 1999. The WIPP is located in bedded salt in southeastern New Mexico and is a deep underground facility for transuranic (TRU) nuclear waste disposal. There are many advantages for placing radioactive wastes in a geologic bedded-salt environment. One desirable mechanical characteristic of salt is that it flows plastically with time ("creeps"). The rate of salt creep is a strong function of temperature and stress differences. Higher temperatures and deviatoric stresses increase the creep rate. As the salt creeps, induced fractures may be closed and eventually healed, which then effectively seals the waste in place. With a backfill of crushed salt emplaced around the waste, the salt creep can cause the crushed salt to reconsolidate and heal to a state similar to intact salt, serving as an efficient seal. Experiments in the WIPP were conducted to investigate the effects of heat generation on the important phenomena and processes in and around the repository (Munson et al. 1987; 1990; 1992a; 1992b). Brine migration towards the heaters was induced from the thermal gradient, while salt creep rates showed an exponential dependence on temperature. The project "Backfill and Material Behavior in Underground Salt Repositories, Phase II" (BAMBUS II) studied the crushed salt backfill and material behavior with heat generation at the Asse mine located near Remlingen, Germany (Bechthold et al. 2004). Increased salt creep rates and significant reconsolidation of the crushed salt were observed at the termination of the experiment. Using the data provided from both projects, exploratory modeling of the thermal-mechanical response of salt has been conducted with varying thermal loading and waste spacing. Increased thermal loading and decreased waste spacing drive the system to higher temperatures, while both factors are desired to reduce costs, as well as decrease the overall footprint of the repository. Higher temperatures increase the rate of salt creep which then effectively seals the waste quicker. Data of the thermal-mechanical response of salt at these higher temperatures is needed to further validate the exploratory modeling and provide meaningful constraints on the repository design. Sandia is a multi program laboratory operated by Sandia Corporation, a Lockheed Martin Company, for the United States Department of Energy's National Nuclear Security Administration under Contract DE-AC04- 94AL85000.

  13. Science, institutional archives and open access: an overview and a pilot survey on the Italian cancer research institutions

    PubMed Central

    2010-01-01

    Background The Open Archive Initiative (OAI) refers to a movement started around the '90s to guarantee free access to scientific information by removing the barriers to research results, especially those related to the ever increasing journal subscription prices. This new paradigm has reshaped the scholarly communication system and is closely connected to the build up of institutional repositories (IRs) conceived to the benefit of scientists and research bodies as a means to keep possession of their own literary production. The IRs are high-value tools which permit authors to gain visibility by enabling rapid access to scientific material (not only publications) thus increasing impact (citation rate) and permitting a multidimensional assessment of research findings. Methods A survey was conducted in March 2010 to mainly explore the managing system in use for archiving the research finding adopted by the Italian Scientific Institutes for Research, Hospitalization and Health Care (IRCCS) of the oncology area within the Italian National Health Service (Servizio Sanitario Nazionale, SSN). They were asked to respond to a questionnaire intended to collect data about institutional archives, metadata formats and posting of full-text documents. The enquiry concerned also the perceived role of the institutional repository DSpace ISS, built up by the Istituto Superiore di Sanità (ISS) and based on a XML scheme for encoding metadata. Such a repository aims at acting as a unique reference point for the biomedical information produced by the Italian research institutions. An in-depth analysis has also been performed on the collection of information material addressed to patients produced by the institutions surveyed. Results The survey respondents were 6 out of 9. The results reveal the use of different practices and standard among the institutions concerning: the type of documentation collected, the software adopted, the use and format of metadata and the conditions of accessibility to the IRs. Conclusions The Italian research institutions in the field of oncology are moving the first steps towards the philosophy of OA. The main effort should be the implementation of common procedures also in order to connect scientific publications to researchers curricula. In this framework, an important effort is represented by the project of ISS aimed to set a common interface able to allow migration of data from partner institutions to the OA compliant repository DSpace ISS. PMID:21172002

  14. Repository Drift Backfilling Demonstrator

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Londe, I.; Dubois, J.Ph.; Bauer, C.

    2008-07-01

    The 'Backfilling Demonstrator' is one of the technological demonstrators developed by ANDRA in the framework of the feasibility studies for a geological repository for high-level long-lived (HL-LL waste) within a clay formation. The demonstrator concerns the standard and supporting backfills as defined in Andra's 2005 design. The standard backfill is intended to fill up almost all drifts of the underground repository in order to limit any deformation of the rock after the degradation of the drift lining. The supporting backfill only concerns a small portion of the volume to be backfilled in order to counter the swelling pressure of themore » swelling clay contained in the sealing structures. The first objective of the demonstrator was to show the possibility of manufacturing a satisfactory backfill, in spite of the exiguity of the underground structures, and of reusing as much as possible the argillite muck. For the purpose of this experiment, the argillite muck was collected on Andra's work-site for the implementation of an underground research laboratory. Still ongoing, the second objective is to follow up the long-term evolution of the backfill. Approximately 200 m{sup 3} of compacted backfill material have been gathered in a large concrete tube simulating a repository drift. The standard backfill was manufactured exclusively with argillite. The supporting backfill was made by forming a mixture of argillite and sand. Operations were carried out mostly at Richwiller, close to Mulhouse, France. The objectives of the demonstrator were met: an application method was tested and proven satisfactory. The resulting dry densities are relatively high, although the moduli of deformation do not always reach the set goal. The selected objective for the demonstrator was a dry density corresponding to a relatively high compaction level (95% of the standard Proctor optimum [SPO]), for both pure argillite and the argillite-sand mixture. The plate-percussion compaction technique was used and proved satisfactory. The measured dry densities are higher than the 95%-SPO objective. The implementation rates remain very low due to the experimental conditions involved. The metal supply mode would need to be revised before any industrial application is contemplated. The Demonstrator Program started in August 2004 and is followed up today over the long term. With that objective in mind, sensors and a water-saturation system have been installed. (author)« less

  15. Strong evidence for a genetic contribution to late-onset Alzheimer's disease mortality: a population-based study.

    PubMed

    Kauwe, John S K; Ridge, Perry G; Foster, Norman L; Cannon-Albright, Lisa A

    2013-01-01

    Alzheimer's disease (AD) is an international health concern that has a devastating effect on patients and families. While several genetic risk factors for AD have been identified much of the genetic variance in AD remains unexplained. There are limited published assessments of the familiality of Alzheimer's disease. Here we present the largest genealogy-based analysis of AD to date. We assessed the familiality of AD in The Utah Population Database (UPDB), a population-based resource linking electronic health data repositories for the state with the computerized genealogy of the Utah settlers and their descendants. We searched UPDB for significant familial clustering of AD to evaluate the genetic contribution to disease. We compared the Genealogical Index of Familiality (GIF) between AD individuals and randomly selected controls and estimated the Relative Risk (RR) for a range of family relationships. Finally, we identified pedigrees with a significant excess of AD deaths. The GIF analysis showed that pairs of individuals dying from AD were significantly more related than expected. This excess of relatedness was observed for both close and distant relationships. RRs for death from AD among relatives of individuals dying from AD were significantly increased for both close and more distant relatives. Multiple pedigrees had a significant excess of AD deaths. These data strongly support a genetic contribution to the observed clustering of individuals dying from AD. This report is the first large population-based assessment of the familiality of AD mortality and provides the only reported estimates of relative risk of AD mortality in extended relatives to date. The high-risk pedigrees identified show a true excess of AD mortality (not just multiple cases) and are greater in depth and width than published AD pedigrees. The presence of these high-risk pedigrees strongly supports the possibility of rare predisposition variants not yet identified.

  16. Research on wild relatives of fruit and nut crops at the Davis repository

    USDA-ARS?s Scientific Manuscript database

    The USDA germplasm repository in Davis is responsible for acquiring, conserving and distributing a broad spectrum of diversity of subtropical and temperate fruit and nut species germplasm to stakeholders around the world. Currently the repository holds over 7000 accessions of germplasm including Act...

  17. 17 CFR 49.2 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION SWAP DATA REPOSITORIES § 49.2... indirectly, controls, is controlled by, or is under common control with, the swap data repository. (2) Asset... “commercial use” means the use of swap data held and maintained by a registered swap data repository for a...

  18. 17 CFR 49.2 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION SWAP DATA REPOSITORIES § 49.2... indirectly, controls, is controlled by, or is under common control with, the swap data repository. (2) Asset... “commercial use” means the use of swap data held and maintained by a registered swap data repository for a...

  19. 75 FR 54528 - Privacy Act of 1974: Implementation of Exemptions United States Citizenship and Immigration...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-08

    ... States Citizenship and Immigration Services-012 Citizenship and Immigration Data Repository System of... and Immigration Data Repository System of Records system of records and this proposed rulemaking. In... Repository (CIDR). The Privacy Act embodies fair information principles in a statutory framework governing...

  20. 10 CFR 60.41 - Standards for issuance of a license.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... REPOSITORIES Licenses License Issuance and Amendment § 60.41 Standards for issuance of a license. A license to receive and possess source, special nuclear, or byproduct material at a geologic repository operations area may be issued by the Commission upon finding that: (a) Construction of the geologic repository...

  1. Factors Affecting Faculty Acceptance and Use of Institutional Repositories in Thailand

    ERIC Educational Resources Information Center

    Ammarukleart, Sujira

    2017-01-01

    Institutional repositories have been introduced as an innovative and alternative technology for scholarly communication and have received considerable attention from scholars across disciplines and around the globe. While some universities in Thailand have developed and implemented institutional repositories for nearly a decade, knowledge of the…

  2. Structure, Features, and Faculty Content in ARL Member Repositories

    ERIC Educational Resources Information Center

    Mercer, Holly; Koenig, Jay; McGeachin, Robert B.; Tucker, Sandra L.

    2011-01-01

    Questions about the optimal way to present repository content to authors, submitters, and end-users, prompted this study. The authors examined, through an observation and a survey, the institutional repositories of peer institutions in the ARL for good practices related to the presentation and organization of faculty-authored institutional…

  3. 75 FR 64643 - Reporting of Security-Based Swap Transaction Data

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-20

    ... information relating to pre-enactment security-based swaps to a registered security-based swap data repository... within 60 days after a registered security- based swap data repository commences operations to receive... repository,\\8\\ and security- based swap execution facility.\\9\\ The Commission has issued an advance notice of...

  4. 75 FR 16360 - Dan Kane; Receipt of Petition for Rulemaking

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-01

    ... certainties in light of the current administration's proposed defunding of the Yucca Mountain Repository for... construction of a mined geologic repository for spent nuclear fuel (Yucca Mountain) from the U.S. Department of... Mountain repository be discontinued for what the petitioner believes are political reasons. The petitioner...

  5. 76 FR 53454 - Privacy Act System of Records

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-26

    ... statutory responsibilities of the OIG; and Acting as a repository and source for information necessary to... in matters relating to the statutory responsibilities of the OIG; and 7. Acting as a repository and.... Acting as a repository and source for information necessary to fulfill the reporting requirements of the...

  6. 76 FR 14058 - Notice of Inventory Completion: University of Wyoming, Anthropology Department, Human Remains...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-15

    ...: University of Wyoming, Anthropology Department, Human Remains Repository, Laramie, WY AGENCY: National Park... Repository, Laramie, WY. The human remains were removed from the east side of the Big Horn Mountains in the... made by University of Wyoming, Anthropology Department, Human Remains Repository, professional staff in...

  7. Building Connections, Collections, and Communities: Increasing the Visibility and Impact of Extension through Institutional Repositories

    ERIC Educational Resources Information Center

    Inefuku, Harrison W.; Franz, Nancy K.

    2015-01-01

    Over the past 20 years, university libraries have developed and manage institutional repositories--digital libraries that provide free, public access to the research, scholarship, and publications of their university's faculty, staff, and students. Although underused by Extension professionals, institutional repositories are powerful tools that…

  8. 78 FR 16713 - Board Meeting; April 16, 2013; Richland, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-18

    ... in a repository. Pursuant to its authority under section 5051 of Public Law 100-203, Nuclear Waste... facility in preparation for eventual disposal in a deep geologic repository. State, local, and regional... DOE's work related to the potential direct disposal in a deep geologic repository of existing SNF...

  9. Ontological Modeling of Educational Resources: A Proposed Implementation for Greek Schools

    ERIC Educational Resources Information Center

    Poulakakis, Yannis; Vassilakis, Kostas; Kalogiannakis, Michail; Panagiotakis, Spyros

    2017-01-01

    In eLearning context searching for suitable educational material is still a challenging issue. During the last two decades, various digital repositories, such as Learning Object Repositories, institutional repositories and latterly Open Educational Resources, have been developed to accommodate collections of learning material that can be used for…

  10. 76 FR 14062 - Notice of Inventory Completion: U.S. Department of the Interior, Bureau of Indian Affairs...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-15

    ... Department, Human Remains Repository, Laramie, WY AGENCY: National Park Service, Interior. ACTION: Notice..., and in the possession of the University of Wyoming, Anthropology Department, Human Remains Repository... University of Wyoming, Anthropology Department, Human Remains Repository, professional staff in consultation...

  11. Types of Online Hierarchical Repository Structures

    ERIC Educational Resources Information Center

    Hershkovitz, Arnon; Azran, Ronit; Hardof-Jaffe, Sharon; Nachmias, Rafi

    2011-01-01

    This study presents an empirical investigation of online hierarchical repositories of items presented to university students in Web-supported course websites, using Web mining methods. To this end, data from 1747 courses were collected, and the use of online repositories of content items in these courses was examined. At a later stage, courses…

  12. 10 CFR 960.3-1-4-2 - Site nomination for characterization.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... SITES FOR A NUCLEAR WASTE REPOSITORY Implementation Guidelines § 960.3-1-4-2 Site nomination for... types under expected repository conditions; evaluations of natural and man-made analogs of the repository and its subsystems, such as geothermally active areas, underground excavations, and case histories...

  13. 10 CFR 60.44 - Changes, tests, and experiments.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... REPOSITORIES Licenses License Issuance and Amendment § 60.44 Changes, tests, and experiments. (a)(1) Following authorization to receive and possess source, special nuclear, or byproduct material at a geologic repository operations area, the DOE may (i) make changes in the geologic repository operations area as described in the...

  14. Evolution of a Digital Repository: One Institution's Experience

    ERIC Educational Resources Information Center

    Owen, Terry M.

    2011-01-01

    In this article, the development of a digital repository is examined, specifically how the focus on acquiring content for the repository has transitioned from faculty-published research to include the gray literature produced by the research centers on campus, including unpublished technical reports and undergraduate research from honors programs.…

  15. Embracing the Future: Embedding Digital Repositories in Higher Education Institutions. Research Brief

    ERIC Educational Resources Information Center

    Hoorens, Stijn; van Dijk, Lidia Villalba; van Stolk, Christian

    2009-01-01

    This briefing paper captures the key findings and recommendations of a study commissioned by the Joint Information Systems Committee on aspects of the strategic commitment of institutions to repository sustainability. This project, labelled EMBRACE (EMBedding Repositories And Consortial Enhancement), is aimed at enhancing the functionality,…

  16. 77 FR 58321 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-20

    ... through http://www.regulations.gov or in hard copy at the site information repositories. Locations, contacts, phone numbers and viewing hours are: Regional Site Information Repository: U.S. EPA Record Center... Repository: New Hanover County Public Library 28401, 201 Chestnut Street, Wilmington, North Carolina 28401...

  17. Developing an Integrated Institutional Repository at Imperial College London

    ERIC Educational Resources Information Center

    Afshari, Fereshteh; Jones, Richard

    2007-01-01

    Purpose: This paper aims to demonstrate how a highly integrated approach to repository development and deployment can be beneficial in producing a successful archive. Design/methodology/approach: Imperial College London undertook a significant specifications process to gather and formalise requirements for its repository system. This was done…

  18. The Microbiology of Subsurface, Salt-Based Nuclear Waste Repositories: Using Microbial Ecology, Bioenergetics, and Projected Conditions to Help Predict Microbial Effects on Repository Performance

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Swanson, Juliet S.; Cherkouk, Andrea; Arnold, Thuro

    This report summarizes the potential role of microorganisms in salt-based nuclear waste repositories using available information on the microbial ecology of hypersaline environments, the bioenergetics of survival under high ionic strength conditions, and “repository microbiology” related studies. In areas where microbial activity is in question, there may be a need to shift the research focus toward feasibility studies rather than studies that generate actual input for performance assessments. In areas where activity is not necessary to affect performance (e.g., biocolloid transport), repository-relevant data should be generated. Both approaches will lend a realistic perspective to a safety case/performance scenario that willmore » most likely underscore the conservative value of that case.« less

  19. The Waste Isolation Pilot Plant transuranic waste repository: A sleeping beauty

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Eriksson, L.G.

    On May 13, 1998, crowning a 24-year United States Department of Energy effort, the US Environmental Protection Agency certified that the deep geological repository for safe disposal of long-lived, transuranic radioactive waste proposed by the DOE at the Waste Isolation Pilot Plant site in New Mexico complied with all applicable environmental radiation protection standards and compliance criteria. Pursuant to the applicable law, the WIPP Land Withdrawal Act of 1992, as amended in 1997, at the decision of the secretary of energy, the WIPP repository could open 30 calendar days after receiving the EPA certification. The secretary of energy announced Maymore » 13, 1998, that he intended to open the WIPP TRUW repository by June 14, 1998. However, at the end of 1998, the opening of the WIPP TRUW repository remains hostage to time-consuming, hazardous-waste-permitting procedures by the state of New Mexico Environment Department and two legal actions. Based on the EPA-verified high safety and the demonstrated risk reduction to both current and future generations offered by the WIPP TRUW repository, it is concluded that the WIPP TRUW repository is a sleeping beauty that will awake, perhaps in stages, and begin its important mission in 1999.« less

  20. Using Linked Open Data and Semantic Integration to Search Across Geoscience Repositories

    NASA Astrophysics Data System (ADS)

    Mickle, A.; Raymond, L. M.; Shepherd, A.; Arko, R. A.; Carbotte, S. M.; Chandler, C. L.; Cheatham, M.; Fils, D.; Hitzler, P.; Janowicz, K.; Jones, M.; Krisnadhi, A.; Lehnert, K. A.; Narock, T.; Schildhauer, M.; Wiebe, P. H.

    2014-12-01

    The MBLWHOI Library is a partner in the OceanLink project, an NSF EarthCube Building Block, applying semantic technologies to enable knowledge discovery, sharing and integration. OceanLink is testing ontology design patterns that link together: two data repositories, Rolling Deck to Repository (R2R), Biological and Chemical Oceanography Data Management Office (BCO-DMO); the MBLWHOI Library Institutional Repository (IR) Woods Hole Open Access Server (WHOAS); National Science Foundation (NSF) funded awards; and American Geophysical Union (AGU) conference presentations. The Library is collaborating with scientific users, data managers, DSpace engineers, experts in ontology design patterns, and user interface developers to make WHOAS, a DSpace repository, linked open data enabled. The goal is to allow searching across repositories without any of the information providers having to change how they manage their collections. The tools developed for DSpace will be made available to the community of users. There are 257 registered DSpace repositories in the United Stated and over 1700 worldwide. Outcomes include: Integration of DSpace with OpenRDF Sesame triple store to provide SPARQL endpoint for the storage and query of RDF representation of DSpace resources, Mapping of DSpace resources to OceanLink ontology, and DSpace "data" add on to provide resolvable linked open data representation of DSpace resources.

  1. Digital Repositories and the Question of Data Usefulness

    NASA Astrophysics Data System (ADS)

    Hughes, J. S.; Downs, R. R.

    2017-12-01

    The advent of ISO standards for trustworthy long-term digital repositories provides both a set of principles to develop long-term data repositories and the instruments to assess them for trustworthiness. Such mandatory high-level requirements are broad enough to be achievable, to some extent, by many scientific data centers, archives, and other repositories. But the requirement that the data be useful in the future, the requirement that is usually considered to be most relevant to the value of the repository for its user communities, largely remains subject to various interpretations and misunderstanding. However, current and future users will be relying on repositories to preserve and disseminate the data and information needed to discover, understand, and utilize these resources to support their research, learning, and decision-making objectives. Therefore, further study is needed to determine the approaches that can be adopted by repositories to make data useful to future communities of users. This presentation will describe approaches for enabling scientific data and related information, such as software, to be useful for current and potential future user communities and will present the methodology chosen to make one science discipline's data useful for both current and future users. The method uses an ontology-based information model to define and capture the information necessary to make the data useful for contemporary and future users.

  2. US/German Collaboration in Salt Repository Research, Design and Operation - 13243

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Steininger, Walter; Hansen, Frank; Biurrun, Enrique

    2013-07-01

    Recent developments in the US and Germany [1-3] have precipitated renewed efforts in salt repository investigations and related studies. Both the German rock salt repository activities and the US waste management programs currently face challenges that may adversely affect their respective current and future state-of-the-art core capabilities in rock salt repository science and technology. The research agenda being pursued by our respective countries leverages collective efforts for the benefit of both programs. The topics addressed by the US/German salt repository collaborations align well with the findings and recommendations summarized in the January 2012 US Blue Ribbon Commission on America's Nuclearmore » Future (BRC) report [4] and are consistent with the aspirations of the key topics of the Strategic Research Agenda of the Implementing Geological Disposal of Radioactive Waste Technology Platform (IGD-TP) [5]. Against this background, a revival of joint efforts in salt repository investigations after some years of hibernation has been undertaken to leverage collective efforts in salt repository research, design, operations, and related issues for the benefit of respective programs and to form a basis for providing an attractive, cost-effective insurance against the premature loss of virtually irreplaceable scientific expertise and institutional memory. (authors)« less

  3. Soil moisture transport in arid site vadose zones. [Evaluation of Hanford as national site for radioactive waste storage

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Brownell, L.E.; Backer, J.G.; Isaacson, R.E.

    1975-07-01

    Data are presented from measurements of soil moisture at the Hanford Reservation. Possible mechanisms for moisture transport in arid and semi-arid climates were studied. Measurements for the lysimeter experiment and the thermocouple psychrometer experiment were continued with a new series of measurements using closely spaced sensors installed to a depth of 1.52 meters. During the 1973-1974 water year the percolation envelope of higher moisture content penetrated to a depth of four meters in the closed-bottom lysimeter and then was eliminated by upward transport of water in late summer. Precipitation during the 1973-1974 water year percolated to a depth of aboutmore » six meters in the open-bottom lysimeter and remains as a residual perched envelope. The increase over normal percolation was due in part to a residual envelope of higher moisture content from the previous water year. Results obtained indicate the advantages of Hanford as a site for a national repository for radioactive waste. (CH)« less

  4. Neurogenetics in Child Neurology: Redefining a Discipline in the Twenty-first Century.

    PubMed

    Kaufmann, Walter E

    2016-12-01

    Increasing knowledge on genetic etiology of pediatric neurologic disorders is affecting the practice of the specialty. I reviewed here the history of pediatric neurologic disorder classification and the role of genetics in the process. I also discussed the concept of clinical neurogenetics, with its role in clinical practice, education, and research. Finally, I propose a flexible model for clinical neurogenetics in child neurology in the twenty-first century. In combination with disorder-specific clinical programs, clinical neurogenetics can become a home for complex clinical issues, repository of genetic diagnostic advances, educational resource, and research engine in child neurology.

  5. Characterize Framework for Igneous Activity at Yucca Mountain, Nevada

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    F. Perry; B. Youngs

    2000-11-06

    The purpose of this Analysis/Model (AMR) report is twofold. (1) The first is to present a conceptual framework of igneous activity in the Yucca Mountain region (YMR) consistent with the volcanic and tectonic history of this region and the assessment of this history by experts who participated in the Probabilistic Volcanic Hazard Analysis (PVHA) (CRWMS M&O 1996). Conceptual models presented in the PVHA are summarized and extended in areas in which new information has been presented. Alternative conceptual models are discussed as well as their impact on probability models. The relationship between volcanic source zones defined in the PVHA andmore » structural features of the YMR are described based on discussions in the PVHA and studies presented since the PVHA. (2) The second purpose of the AMR is to present probability calculations based on PVHA outputs. Probability distributions are presented for the length and orientation of volcanic dikes within the repository footprint and for the number of eruptive centers located within the repository footprint (conditional on the dike intersecting the repository). The probability of intersection of a basaltic dike within the repository footprint was calculated in the AMR ''Characterize Framework for Igneous Activity at Yucca Mountain, Nevada'' (CRWMS M&O 2000g) based on the repository footprint known as the Enhanced Design Alternative [EDA II, Design B (CRWMS M&O 1999a; Wilkins and Heath 1999)]. Then, the ''Site Recommendation Design Baseline'' (CRWMS M&O 2000a) initiated a change in the repository design, which is described in the ''Site Recommendation Subsurface Layout'' (CRWMS M&O 2000b). Consequently, the probability of intersection of a basaltic dike within the repository footprint has also been calculated for the current repository footprint, which is called the 70,000 Metric Tons of Uranium (MTU) No-Backfill Layout (CRWMS M&O 2000b). The calculations for both footprints are presented in this AMR. In addition, the probability of an eruptive center(s) forming within the repository footprint is calculated and presented in this AMR for both repository footprint designs. This latter type of calculation was not included in the PVHA.« less

  6. Bedside, classroom and bench: collaborative strategies to generate evidence-based knowledge for nursing practice.

    PubMed

    Weaver, Charlotte A; Warren, Judith J; Delaney, Connie

    2005-12-01

    The rise of evidence-base practice (EBP) as a standard for care delivery is rapidly emerging as a global phenomenon that is transcending political, economic and geographic boundaries. Evidence-based nursing (EBN) addresses the growing body of nursing knowledge supported by different levels of evidence for best practices in nursing care. Across all health care, including nursing, we face the challenge of how to most effectively close the gap between what is known and what is practiced. There is extensive literature on the barriers and difficulties of translating research findings into practical application. While the literature refers to this challenge as the "Bench to Bedside" lag, this paper presents three collaborative strategies that aim to minimize this gap. The Bedside strategy proposes to use the data generated from care delivery and captured in the massive data repositories of electronic health record (EHR) systems as empirical evidence that can be analysed to discover and then inform best practice. In the Classroom strategy, we present a description for how evidence-based nursing knowledge is taught in a baccalaureate nursing program. And finally, the Bench strategy describes applied informatics in converting paper-based EBN protocols into the workflow of clinical information systems. Protocols are translated into reference and executable knowledge with the goal of placing the latest scientific knowledge at the fingertips of front line clinicians. In all three strategies, information technology (IT) is presented as the underlying tool that makes this rapid translation of nursing knowledge into practice and education feasible.

  7. Analysis of fluid flow and solute transport through a single fracture with variable apertures intersecting a canister: Comparison between fractal and Gaussian fractures

    NASA Astrophysics Data System (ADS)

    Liu, L.; Neretnieks, I.

    Canisters with spent nuclear fuel will be deposited in fractured crystalline rock in the Swedish concept for a final repository. The fractures intersect the canister holes at different angles and they have variable apertures and therefore locally varying flowrates. Our previous model with fractures with a constant aperture and a 90° intersection angle is now extended to arbitrary intersection angles and stochastically variable apertures. It is shown that the previous basic model can be simply amended to account for these effects. More importantly, it has been found that the distributions of the volumetric and the equivalent flow rates are all close to the Normal for both fractal and Gaussian fractures, with the mean of the distribution of the volumetric flow rate being determined solely by the hydraulic aperture, and that of the equivalent flow rate being determined by the mechanical aperture. Moreover, the standard deviation of the volumetric flow rates of the many realizations increases with increasing roughness and spatial correlation length of the aperture field, and so does that of the equivalent flow rates. Thus, two simple statistical relations can be developed to describe the stochastic properties of fluid flow and solute transport through a single fracture with spatially variable apertures. This obviates, then, the need to simulate each fracture that intersects a canister in great detail, and allows the use of complex fractures also in very large fracture network models used in performance assessment.

  8. PROBABILISTIC RISK ANALYSIS OF RADIOACTIVE WASTE DISPOSALS - a case study

    NASA Astrophysics Data System (ADS)

    Trinchero, P.; Delos, A.; Tartakovsky, D. M.; Fernandez-Garcia, D.; Bolster, D.; Dentz, M.; Sanchez-Vila, X.; Molinero, J.

    2009-12-01

    The storage of contaminant material in superficial or sub-superficial repositories, such as tailing piles for mine waste or disposal sites for low and intermediate nuclear waste, poses a potential threat for the surrounding biosphere. The minimization of these risks can be achieved by supporting decision-makers with quantitative tools capable to incorporate all source of uncertainty within a rigorous probabilistic framework. A case study is presented where we assess the risks associated to the superficial storage of hazardous waste close to a populated area. The intrinsic complexity of the problem, involving many events with different spatial and time scales and many uncertainty parameters is overcome by using a formal PRA (probabilistic risk assessment) procedure that allows decomposing the system into a number of key events. Hence, the failure of the system is directly linked to the potential contamination of one of the three main receptors: the underlying karst aquifer, a superficial stream that flows near the storage piles and a protection area surrounding a number of wells used for water supply. The minimal cut sets leading to the failure of the system are obtained by defining a fault-tree that incorporates different events including the failure of the engineered system (e.g. cover of the piles) and the failure of the geological barrier (e.g. clay layer that separates the bottom of the pile from the karst formation). Finally the probability of failure is quantitatively assessed combining individual independent or conditional probabilities that are computed numerically or borrowed from reliability database.

  9. A University Library Creates a Digital Repository for Documenting and Disseminating Community Engagement

    ERIC Educational Resources Information Center

    Miller, William A.; Billings, Marilyn

    2012-01-01

    Digital repositories are new tools for documenting the accumulated scholarly work produced at academic institutions and disseminating that material broadly via the internet. Digital repositories support all file types and can be adapted to meet the custom design specifications of individual institutions. A section for community engagement…

  10. Using OAI-PMH and METS for Exporting Metadata and Digital Objects between Repositories

    ERIC Educational Resources Information Center

    Bell, Jonathan; Lewis, Stuart

    2006-01-01

    Purpose: To examine the relationship between deposit of electronic theses in institutional and archival repositories. Specifically the paper considers the automated export of theses for deposit in the archival repository in continuation of the existing arrangement in Wales for paper-based theses. Design/methodology/approach: The paper presents a…

  11. 77 FR 3745 - Establishment of a One-Year Retention Period for Patent-Related Papers That Have Been Scanned...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-25

    ... File Wrapper System or the Supplemental Complex Repository for Examiners AGENCY: United States Patent... (IFW) or the Supplemental Complex Repository for Examiners (SCORE). The USPTO has considered the... Supplemental Complex Repository for Examiners, 76 FR 53667 (August 29, 2011), 1370 Off. Gaz. Pat. Office 211...

  12. The World Sugarcane and Related Grasses Collection at USDA/ARS Genebank Repository in Miami, Florida, USA

    USDA-ARS?s Scientific Manuscript database

    In early 1980’s the USDA-ARS established the National Plant Germplasm System (NPGS) a network of gene banks to preserve genetic resources of importance to National and International agriculture. The National Clonal Germplasm Repository (NCGR) in Miami, Florida is one of these repositories. This repo...

  13. 10 CFR 960.5-2-1 - Population density and distribution.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... SITES FOR A NUCLEAR WASTE REPOSITORY Preclosure Guidelines Preclosure Radiological Safety § 960.5-2-1... repository operation and closure, (1) the expected average radiation dose to members of the public within any...) Disqualifying conditions. A site shall be disqualified if— (1) Any surface facility of a repository would be...

  14. 75 FR 54642 - Privacy Act of 1974; United States Citizenship and Immigration Services-012 Citizenship and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-08

    ... Repository System of Records AGENCY: Privacy Office, DHS. ACTION: Notice of Privacy Act system of records... Immigration Services 012 Citizenship and Immigration Data Repository System of Records.'' Citizenship and Immigration Data Repository is a mirror copy of USCIS's major immigrant and non-immigrant benefits databases...

  15. 75 FR 66110 - Guidelines for Use of Stored Specimens and Access to Ancillary Data and Proposed Cost Schedule...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-27

    ... repository of datasets from completed studies, biospecimens, and ancillary data. The Division intends to make... Sharing Policy. The Division has established an internal committee, the Biospecimen Repository Access and Data Sharing Committee (BRADSC), to oversee the repository access and data sharing program. The purpose...

  16. 10 CFR 960.3-2-1 - Site screening for potentially acceptable sites.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY Implementation Guidelines § 960.3-2-1 Site screening for... first repository, the process shall begin with site-screening activities that consider large land masses... repositories, the Secretary shall first identify the State within which the site is located in a decision-basis...

  17. Institutional Repositories, Open Access, and Scholarly Communication: A Study of Conflicting Paradigms

    ERIC Educational Resources Information Center

    Cullen, Rowena; Chawner, Brenda

    2011-01-01

    The Open Access movement of the past decade, and institutional repositories developed by universities and academic libraries as a part of that movement, have openly challenged the traditional scholarly communication system. This article examines the growth of repositories around the world, and summarizes a growing body of evidence of the response…

  18. 77 FR 22632 - Privacy Act of 1974; System of Records

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-16

    ...--Repository (SCIDO-R)-VA'' (108VA11S) as set forth in the Federal Register 74 FR 11185-11186 dated March 16.... SUPPLEMENTARY INFORMATION: The Spinal Cord Injury and Disorders Outcomes--Repository (SCIDO-R) provides a registry of veterans with spinal cord injury and disorders (SCI&D). This repository contains pertinent...

  19. 75 FR 8742 - Notice of Inventory Completion: Stephen F. Austin State University, Nacogdoches, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-25

    ... repository of the anthropology lab some time after 1975. No known individual was identified. No associated... the repository of the Stephen F. Austin State University anthropology lab. No known individual was.... The human remains are located in the repository of the Stephen F. Austin State University anthropology...

  20. Digital Libraries and Repositories in India: An Evaluative Study

    ERIC Educational Resources Information Center

    Mittal, Rekha; Mahesh, G.

    2008-01-01

    Purpose: The purpose of this research is to identify and evaluate the collections within digital libraries and repositories in India available in the public domain. Design/methodology/approach: The digital libraries and repositories were identified through a study of the literature, as well as internet searching and browsing. The resulting digital…

  1. 10 CFR 960.3-2-2-2 - Selection of sites within geohydrologic settings.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... OF POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY Implementation Guidelines § 960.3-2-2-2 Selection... nominated as suitable for characterization. For purposes of the second and subsequent repositories, due... suitable for the development of a repository under the qualifying condition of each guideline specified in...

  2. 75 FR 81371 - Privacy Act of 1974: Implementation of Exemptions; Department of Homeland Security/United States...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-28

    ... Citizenship and Immigration Services- 012 Citizenship and Immigration Data Repository System of Records AGENCY... Immigration Data Repository System of Records'' from certain provisions of the Privacy Act. Specifically, the... Immigration Services-012 Citizenship and Immigration Data Repository System of Records'' from one or more...

  3. Creating Complex Repository Collections, Such as Journals, with Manakin

    ERIC Educational Resources Information Center

    Koenig, Jack; Mikeal, Adam

    2010-01-01

    Purpose: The purpose of this paper is to report on a devised method of collection organisation within a DSpace repository using a Manakin theme and descriptive metadata. Design/methodology/approach: Using a Manakin theme, a user interface for a repository collection containing the contents of a serial was created to divide the collection into…

  4. History, Context, and Policies of a Learning Object Repository

    ERIC Educational Resources Information Center

    Simpson, Steven Marshall

    2016-01-01

    Learning object repositories, a form of digital libraries, are robust systems that provide educators new ways to search for educational resources, collaborate with peers, and provide instruction to students in unique and varied ways. This study examines a learning object repository created by a large suburban school district to increase teaching…

  5. 78 FR 22350 - Self-Regulatory Organizations; ICE Clear Credit LLC; Notice of Filing and Order Granting...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-15

    ... governing security-based swap data repositories and security-based swap reporting. See, e.g., Pub. L. No... Depository Trust & Clearing Corporation (``DTCC''), in conjunction with DTCC Data Repository (U.S.) LLC.\\40... 75208 (Dec. 2, 2010); Security-Based Swap Data Repository Registration, Duties, and Core Principles...

  6. 75 FR 61373 - Proposed Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-05

    ... located at the community map repository (see below) for exact locations of all BFEs to be changed. Send... located at the community map repository (see below) for exact locations of all BFEs to be changed. Send.... Please refer to the revised Flood Insurance Rate Map located at the community map repository (see below...

  7. 76 FR 61649 - Proposed Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-05

    ... Insurance Rate Map located at the community map repository (see below) for exact locations of all BFEs to be... Insurance Rate Map located at the community map repository (see below) for exact locations of all BFEs to be... revised Flood Insurance Rate Map located at the community map repository (see below) for exact locations...

  8. Three-dimensional thermal analysis of a high-level waste repository

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Altenbach, T.J.

    1979-04-01

    The analysis used the TRUMP computer code to evaluate the thermal fields for six repository scenarios that studied the effects of room ventilation, room backfill, and repository thermal diffusivity. The results for selected nodes are presented as plots showing the effect of temperature as a function of time. 15 figures, 6 tables.

  9. Data Stewardship throughout the Ocean Research Data Life Cycle

    NASA Astrophysics Data System (ADS)

    Chandler, Cynthia; Groman, Robert; Allison, Molly; Wiebe, Peter; Glover, David

    2013-04-01

    The Biological and Chemical Oceanography Data Management Office (BCO-DMO) works in partnership with ocean science investigators to publish data from research projects funded by the Biological and Chemical Oceanography Sections and the Office of Polar Programs Antarctic Organisms & Ecosystems Program (OPP ANT) at the U.S. National Science Foundation. Since 2006, researchers have been contributing data to the BCO-DMO data system, and it has developed into a rich repository of data from ocean, coastal and Great Lakes research programs. The end goals of the BCO-DMO are to ensure preservation of NSF funded project data and to provide open access to those data; achievement of those goals is attained through successful completion of a series of related phases. BCO-DMO has developed an end-to-end data stewardship process that includes all phases of the data life cycle: (1) providing data management advice to investigators during the proposal writing stage; (2) registering their funded project at BCO-DMO; (3) adding data and supporting documentation to the BCO-DMO data repository; (4) providing geospatial and text-based data access systems that support data discovery, access, display, assessment, integration, and export of data resources; (5) exploring mechanisms for exchange of data with complementary repositories; (6) publication of data sets to provide publishers of the peer-reviewed literature with citable references (Digital Object Identifiers) and to encourage proper citation and attribution of data sets in the future and (7) submission of final data sets for preservation in the appropriate long-term data archive. Strategic development of collaborative partnerships with complementary data management organizations is essential to sustainable coverage of the full data life cycle from research proposal through preservation of the final data products. Development and incorporation of controlled vocabularies, domain-specific ontologies and globally unique, persistent identifiers to unambiguously identify resources of interest curated by and available from BCO-DMO have significantly enabled progress toward interoperability with partner systems. Several important components have emerged from early collaborative relationships: (1) identifying a trusted authoritative source of complementary content and the appropriate contact; (2) determining the globally unique, persistent identifier for resources of interest and (3) negotiating the requisite syntactic and semantic exchange systems. An added benefit is the ability to use globally unique, persistent resource identifiers to identify and compare related content in other repositories, thus enabling us to improve the accuracy of content in the BCO-DMO data collection. Results from a recent community discussion at the January 2013 Federation of Earth Science Information Partners (ESIP) meeting will be presented. Mindful of the NSF EarthCube initiative in the United States, the ESIP discussion was an effort to identify commonalities and differences in the way different communities meet the challenges of data stewardship throughout the full data life cycle and to determine any gaps that currently exist. BCO-DMO: http://bco-dmo.org ESIP: http://esipfed.org/

  10. Preliminary safety analysis of the Baita Bihor radioactive waste repository, Romania

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Little, Richard; Bond, Alex; Watson, Sarah

    2007-07-01

    A project funded under the European Commission's Phare Programme 2002 has undertaken an in-depth analysis of the operational and post-closure safety of the Baita Bihor repository. The repository has accepted low- and some intermediate-level radioactive waste from industry, medical establishments and research activities since 1985 and the current estimate is that disposals might continue for around another 20 to 35 years. The analysis of the operational and post-closure safety of the Baita Bihor repository was carried out in two iterations, with the second iteration resulting in reduced uncertainties, largely as a result taking into account new information on the hydrologymore » and hydrogeology of the area, collected as part of the project. Impacts were evaluated for the maximum potential inventory that might be available for disposal to Baita Bihor for a number of operational and postclosure scenarios and associated conceptual models. The results showed that calculated impacts were below the relevant regulatory criteria. In light of the assessment, a number of recommendations relating to repository operation, optimisation of repository engineering and waste disposals, and environmental monitoring were made. (authors)« less

  11. Remediation by in-situ solidification/stabilisation of Ardeer landfill, Scotland

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wyllie, M.; Esnault, A.; Barker, P.

    1997-12-31

    The Ardeer Landfill site at ICI Explosives factory on the west coast of Scotland had been a repository for waste from the site for 40 years. In order to safeguard the local environment ICI Explosives, with approval of Local Authorities and the Clyde River Purification Board put into action a programme of investigation and planning which culminated in the in-situ treatment of 10,000 m3 of waste within the landfill by a deep mixing method using the {open_quotes}Colmix{close_quotes} system. The paper describes in varying degrees of detail the remediation from investigation to the execution of the in-situ stabilisation and presents themore » post construction monitoring results.« less

  12. Carbon dioxide (CO2) sequestration in deep saline aquifers and formations: Chapter 3

    USGS Publications Warehouse

    Rosenbauer, Robert J.; Thomas, Burt

    2010-01-01

    Carbon dioxide (CO2) capture and sequestration in geologic media is one among many emerging strategies to reduce atmospheric emissions of anthropogenic CO2. This chapter looks at the potential of deep saline aquifers – based on their capacity and close proximity to large point sources of CO2 – as repositories for the geologic sequestration of CO2. The petrochemical characteristics which impact on the suitability of saline aquifers for CO2 sequestration and the role of coupled geochemical transport models and numerical tools in evaluating site feasibility are also examined. The full-scale commercial CO2 sequestration project at Sleipner is described together with ongoing pilot and demonstration projects.

  13. Repository Planning, Design, and Engineering: Part II-Equipment and Costing.

    PubMed

    Baird, Phillip M; Gunter, Elaine W

    2016-08-01

    Part II of this article discusses and provides guidance on the equipment and systems necessary to operate a repository. The various types of storage equipment and monitoring and support systems are presented in detail. While the material focuses on the large repository, the requirements for a small-scale startup are also presented. Cost estimates and a cost model for establishing a repository are presented. The cost model presents an expected range of acquisition costs for the large capital items in developing a repository. A range of 5,000-7,000 ft(2) constructed has been assumed, with 50 frozen storage units, to reflect a successful operation with growth potential. No design or engineering costs, permit or regulatory costs, or smaller items such as the computers, software, furniture, phones, and barcode readers required for operations have been included.

  14. An open repositories network development for medical teaching resources.

    PubMed

    Soula, Gérard; Darmoni, Stefan; Le Beux, Pierre; Renard, Jean-Marie; Dahamna, Badisse; Fieschi, Marius

    2010-01-01

    The lack of interoperability between repositories of heterogeneous and geographically widespread data is an obstacle to the diffusion, sharing and reutilization of those data. We present the development of an open repositories network taking into account both the syntactic and semantic interoperability of the different repositories and based on international standards in this field. The network is used by the medical community in France for the diffusion and sharing of digital teaching resources. The syntactic interoperability of the repositories is managed using the OAI-PMH protocol for the exchange of metadata describing the resources. Semantic interoperability is based, on one hand, on the LOM standard for the description of resources and on MESH for the indexing of the latter and, on the other hand, on semantic interoperability management designed to optimize compliance with standards and the quality of the metadata.

  15. High Integrity Can Design Interfaces

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Shaber, E.L.

    1998-08-01

    The National Spent Nuclear Fuel Program is chartered with facilitating the disposition of DOE-owned spent nuclear fuel to allow disposal at a geologic repository. This is done through coordination with the repository program and by assisting DOE Site owners of SNF with needed information, standardized requirements, packaging approaches, etc. The High Integrity Can (HIC) will be manufactured to provide a substitute or barrier enhancement for normal fuel geometry and cladding. The can would be nested inside the DOE standardized canister which is designed to interface with the repository waste package. The HIC approach may provide the following benefits over typicalmore » canning approaches for DOE SNF. (a) It allows ready calculation and management of criticality issues for miscellaneous. (b) It segments and further isolates damaged or otherwise problem materials from normal SNF in the repository package. (c) It provides a very long term corrosion barrier. (d) It provides an extra internal pressure barrier for particulates, gaseous fission products, hydrogen, and water vapor. (e) It delays any potential release of fission products to the repository environment. (f) It maintains an additional level of fuel geometry control during design basis accidents, rock-fall, and seismic events. (g) When seal welded, it could provide the additional containment required for shipments involving plutonium content in excess of 20 Ci. (10 CFR 71.63.b) if integrated with an appropriate cask design. Long term corrosion protection is central to the HIC concept. The material selected for the HIC (Hastelloy C-22) has undergone extensive testing for repository service. The most severe theoretical interactions between iron, repository water containing chlorides and other repository construction materials have been tested. These expected chemical species have not been shown capable of corroding the selected HIC material. Therefore, the HIC should provide a significant barrier to DOE SNF dispersal long after most commercial SNF has degraded and begun moving into the repository environment.« less

  16. The Challenges of Releasing Human Data for Analysis

    NASA Technical Reports Server (NTRS)

    Fitts, Mary; Van Baalen, Mary; Johnson-Throop, Kathy; Lee, Lesley; Havelka, Jacque; Wear, Mary; Thomas, Diedre M.

    2011-01-01

    The NASA Johnson Space Center s (NASA JSC) Committee for the Protection of Human Subjects (CPHS) recently approved the formation of two human data repositories: the Lifetime Surveillance of Astronaut Health Repository (LSAH-R) for clinical data and the Life Sciences Data Archive Repository (LSDA-R) for research data. The establishment of these repositories forms the foundation for the release of data and information beyond the scope for which the data was originally collected. The release of clinical and research data and information is primarily managed by two NASA groups: the Evidence Base Working Group (EBWG), consisting of members of both repositories, and the LSAH Policy Board. The goal of unifying these repositories and their processes is to provide a mutually supportive approach to handling medical and research data, to enhance the use of medical and research data to reduce risk, and to promote the understanding of space physiology, countermeasures and other mitigation strategies. Over the past year, both repositories have received over 100 data and information requests from a wide variety of requesters. The disposition of these requests has highlighted the challenges faced when attempting to make data collected on a unique set of subjects available beyond the original intent for which the data were collected. As the EBWG works through each request, many considerations must be factored into account when deciding what data can be shared and how - from the Privacy Act of 1974 and the Health Insurance Portability and Accountability Act (HIPAA), to NASA s Health Information Management System (10HIMS) and Human Experimental and Research Data Records (10HERD) access requirements. Additional considerations include the presence of the data in the repositories and vetting requesters for legitimacy of their use of the data. Additionally, fair access must be ensured for intramural, as well as extramural investigators. All of this must be considered in the formulation of the charters, policies and workflows for the human data repositories at NASA.

  17. Sharing individual participant data from clinical trials: an opinion survey regarding the establishment of a central repository.

    PubMed

    Tudur Smith, Catrin; Dwan, Kerry; Altman, Douglas G; Clarke, Mike; Riley, Richard; Williamson, Paula R

    2014-01-01

    Calls have been made for increased access to individual participant data (IPD) from clinical trials, to ensure that complete evidence is available. However, despite the obvious benefits, progress towards this is frustratingly slow. In the meantime, many systematic reviews have already collected IPD from clinical trials. We propose that a central repository for these IPD should be established to ensure that these datasets are safeguarded and made available for use by others, building on the strengths and advantages of the collaborative groups that have been brought together in developing the datasets. Evaluate the level of support, and identify major issues, for establishing a central repository of IPD. On-line survey with email reminders. 71 reviewers affiliated with the Cochrane Collaboration's IPD Meta-analysis Methods Group were invited to participate. 30 (42%) invitees responded: 28 (93%) had been involved in an IPD review and 24 (80%) had been involved in a randomised trial. 25 (83%) agreed that a central repository was a good idea and 25 (83%) agreed that they would provide their IPD for central storage. Several benefits of a central repository were noted: safeguarding and standardisation of data, increased efficiency of IPD meta-analyses, knowledge advancement, and facilitating future clinical, and methodological research. The main concerns were gaining permission from trial data owners, uncertainty about the purpose of the repository, potential resource implications, and increased workload for IPD reviewers. Restricted access requiring approval, data security, anonymisation of data, and oversight committees were highlighted as issues under governance of the repository. There is support in this community of IPD reviewers, many of whom are also involved in clinical trials, for storing IPD in a central repository. Results from this survey are informing further work on developing a repository of IPD which is currently underway by our group.

  18. Revision history aware repositories of computational models of biological systems.

    PubMed

    Miller, Andrew K; Yu, Tommy; Britten, Randall; Cooling, Mike T; Lawson, James; Cowan, Dougal; Garny, Alan; Halstead, Matt D B; Hunter, Peter J; Nickerson, David P; Nunns, Geo; Wimalaratne, Sarala M; Nielsen, Poul M F

    2011-01-14

    Building repositories of computational models of biological systems ensures that published models are available for both education and further research, and can provide a source of smaller, previously verified models to integrate into a larger model. One problem with earlier repositories has been the limitations in facilities to record the revision history of models. Often, these facilities are limited to a linear series of versions which were deposited in the repository. This is problematic for several reasons. Firstly, there are many instances in the history of biological systems modelling where an 'ancestral' model is modified by different groups to create many different models. With a linear series of versions, if the changes made to one model are merged into another model, the merge appears as a single item in the history. This hides useful revision history information, and also makes further merges much more difficult, as there is no record of which changes have or have not already been merged. In addition, a long series of individual changes made outside of the repository are also all merged into a single revision when they are put back into the repository, making it difficult to separate out individual changes. Furthermore, many earlier repositories only retain the revision history of individual files, rather than of a group of files. This is an important limitation to overcome, because some types of models, such as CellML 1.1 models, can be developed as a collection of modules, each in a separate file. The need for revision history is widely recognised for computer software, and a lot of work has gone into developing version control systems and distributed version control systems (DVCSs) for tracking the revision history. However, to date, there has been no published research on how DVCSs can be applied to repositories of computational models of biological systems. We have extended the Physiome Model Repository software to be fully revision history aware, by building it on top of Mercurial, an existing DVCS. We have demonstrated the utility of this approach, when used in conjunction with the model composition facilities in CellML, to build and understand more complex models. We have also demonstrated the ability of the repository software to present version history to casual users over the web, and to highlight specific versions which are likely to be useful to users. Providing facilities for maintaining and using revision history information is an important part of building a useful repository of computational models, as this information is useful both for understanding the source of and justification for parts of a model, and to facilitate automated processes such as merges. The availability of fully revision history aware repositories, and associated tools, will therefore be of significant benefit to the community.

  19. Task-Based Navigation of a Taxonomy Interface to a Digital Repository

    ERIC Educational Resources Information Center

    Khoo, Christopher S. G.; Wang, Zhonghong; Chaudhry, Abdus Sattar

    2012-01-01

    Introduction: This is a study of hierarchical navigation; how users browse a taxonomy-based interface to an organizational repository to locate information resources. The study is part of a project to develop a taxonomy for an library and information science department to organize resources and support user browsing in a digital repository.…

  20. 17 CFR 43.3 - Method and timing for real-time public reporting.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... § 43.5. (3) Prohibitions on disclosure of data. (i) If there is a registered swap data repository for... disclosure is made no earlier than the transmittal of such data to a registered swap data repository for... such data by a registered swap data repository unless: (A) Such disclosure is made no earlier than the...

  1. 17 CFR 45.10 - Reporting to a single swap data repository.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... the swap data repository to which the first report of required swap creation data is made pursuant to... designated contract market that reports required swap creation data as required by § 45.3 shall report all... of the swap data repository to which required swap creation data is reported by the swap execution...

  2. 17 CFR 45.10 - Reporting to a single swap data repository.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ..., which shall be the swap data repository to which the first report of required swap creation data is made... designated contract market that reports required swap creation data as required by § 45.3 shall report all... of the swap data repository to which required swap creation data is reported by the swap execution...

  3. 17 CFR 45.10 - Reporting to a single swap data repository.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... the swap data repository to which the first report of required swap creation data is made pursuant to... designated contract market that reports required swap creation data as required by § 45.3 shall report all... of the swap data repository to which required swap creation data is reported by the swap execution...

  4. Planting Seeds for a Successful Institutional Repository: Role of the Archivist as Manager, Designer, and Policymaker

    ERIC Educational Resources Information Center

    Watterworth, Melissa

    2009-01-01

    Recent surveys indicate that many colleges and universities have reached a pivotal moment in assessing the function and future development of their institutional repositories. Other surveys convey that archivists are participating in the development and implementation of institutional repositories at a variety of levels and have contributed to the…

  5. 75 FR 78892 - Reporting Certain Post-Enactment Swap Transactions

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-17

    ...)--to a registered swap data repository (``SDR'') or to the Commission. Each category of data is subject... expired by that date. \\5\\ The term ``swap data repository'' is defined in Section 1a(48) of the CEA to... date of the enactment of this subsection shall be reported to a registered swap data repository or the...

  6. 76 FR 53667 - Establishing a One-Year Retention Period for Patent-Related Papers That Have Been Scanned Into...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-29

    ... System or the Supplemental Complex Repository for Examiners AGENCY: United States Patent and Trademark... been scanned into the Image File Wrapper system (IFW) or the Supplemental Complex Repository for..., the USPTO had fully deployed SCORE, a data repository system designed to augment IFW with the capture...

  7. 75 FR 70025 - Notice of Inventory Completion: U.S. Department of the Interior, Bureau of Reclamation, Pacific...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-16

    ... Repository, Nespelem, WA AGENCY: National Park Service, Interior. ACTION: Notice. Notice is hereby given in... Repository, Nespelem, WA. The human remains were removed from Grant County, WA. This notice is published as... Washington State University. In 2006, they were transferred to the Colville Tribal Repository for curation...

  8. The Situation of Open Access Institutional Repositories in Spain: 2009 Report

    ERIC Educational Resources Information Center

    Melero, Remedios; Abadal, Ernest; Abad, Francisca; Rodriguez-Gairin, Josep Manel

    2009-01-01

    Introduction: The DRIVER I project drew up a detailed report of European repositories based on data gathered in a survey in which Spain's participation was very low. This created a highly distorted image of the implementation of repositories in Spain. This study aims to analyse the current state of Spanish open-access institutional repositories…

  9. The Efficacy of Institutional Repositories: Reflections on the Development of a Personalised Collection on UPSpace

    ERIC Educational Resources Information Center

    Olivier, Elsabe

    2007-01-01

    There is much speculation that the development of institutional repositories will impact on or even change the traditional scholarly communication process. The purpose of this conversation is to introduce the reader to the use of and response to institutional repositories which were initiated by the Open Access Initiative. The concept of…

  10. Repository Collection Policies: Is a Liberal and Inclusive Policy Helpful or Harmful?

    ERIC Educational Resources Information Center

    Bankier, Jean-Gabriel; Smith, Courtney

    2010-01-01

    Institutional repositories have been established by most university libraries but their level of success has varied. Determining what belongs in such repositories has been the subject of some discussion but research would suggest that a broader rather than narrower compass is a positive approach to adopt. By seeking out a variety of content types,…

  11. 10 CFR 960.3-2-3 - Recommendation of sites for characterization.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY Implementation Guidelines § 960.3-2-3 Recommendation of sites... characterization for the selection of the first repository, the Secretary shall recommend in writing to the..., and, after the first repository, consideration of regionality in §§ 960.3-1-1, 960.3-1-2, and 960.3-1...

  12. A Comparison of Subject and Institutional Repositories in Self-Archiving Practices

    ERIC Educational Resources Information Center

    Xia, Jingfeng

    2008-01-01

    The disciplinary culture theory presumes that if a scholar has been familiar with self-archiving through an existing subject-based repository, this scholar will be more enthusiastic about contributing his/her research to an institutional repository than one who has not had the experience. To test the theory, this article examines self-archiving…

  13. 75 FR 62435 - Agency Information Collection Activities: Submission for the Office of Management and Budget (OMB...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-08

    ... Proposed Geologic Repository at Yucca Mountain, Nevada.'' 3. Current OMB approval number: 3150-0199. [[Page... potential high-level waste geologic repository site, or wishing to participate in a license application review for the potential geologic repository. 7. An estimate of the number of annual responses: 3. 8. The...

  14. 77 FR 70190 - Agency Information Collection Activities: Submission for the Office of Management and Budget (OMB...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-23

    ... Repositories.'' 3. Current OMB approval number: 3150-0127. 4. The form number if applicable: N/A. 5. How often... the NRC staff regarding review of a potential high-level radioactive waste geologic repository site, or wishing to participate in a license application review for a potential geologic repository (other...

  15. Collaborative Learning Utilizing a Domain-Based Shared Data Repository to Enhance Learning Outcomes

    ERIC Educational Resources Information Center

    Lubliner, David; Widmeyer, George; Deek, Fadi P.

    2009-01-01

    The objective of this study was to determine whether there was a quantifiable improvement in learning outcomes by integrating course materials in a 4-year baccalaureate program, utilizing a knowledge repository with a conceptual map that spans a discipline. Two new models were developed to provide the framework for this knowledge repository. A…

  16. My Three Wishes for Digital Repositories. Building Digital Libraries

    ERIC Educational Resources Information Center

    Huwe, Terence K.

    2005-01-01

    In this column on digital repository management, the author defines three areas within the sphere of digital repositories that need work. The first two pertain to information architecture, while the last one pertains to taking action. The author's first "wish" is for top-notch library Web sites that act as a gateway to any sphere of knowledge. He…

  17. Preliminary performance assessment for the Waste Isolation Pilot Plant, December 1992. Volume 5, Uncertainty and sensitivity analyses of gas and brine migration for undisturbed performance

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1993-08-01

    Before disposing of transuranic radioactive waste in the Waste Isolation Pilot Plant (WIPP), the United States Department of Energy (DOE) must evaluate compliance with applicable long-term regulations of the United States Environmental Protection Agency (EPA). Sandia National Laboratories is conducting iterative performance assessments (PAs) of the WIPP for the DOE to provide interim guidance while preparing for a final compliance evaluation. This volume of the 1992 PA contains results of uncertainty and sensitivity analyses with respect to migration of gas and brine from the undisturbed repository. Additional information about the 1992 PA is provided in other volumes. Volume 1 containsmore » an overview of WIPP PA and results of a preliminary comparison with 40 CFR 191, Subpart B. Volume 2 describes the technical basis for the performance assessment, including descriptions of the linked computational models used in the Monte Carlo analyses. Volume 3 contains the reference data base and values for input parameters used in consequence and probability modeling. Volume 4 contains uncertainty and sensitivity analyses with respect to the EPA`s Environmental Standards for the Management and Disposal of Spent Nuclear Fuel, High-Level and Transuranic Radioactive Wastes (40 CFR 191, Subpart B). Finally, guidance derived from the entire 1992 PA is presented in Volume 6. Results of the 1992 uncertainty and sensitivity analyses indicate that, conditional on the modeling assumptions and the assigned parameter-value distributions, the most important parameters for which uncertainty has the potential to affect gas and brine migration from the undisturbed repository are: initial liquid saturation in the waste, anhydrite permeability, biodegradation-reaction stoichiometry, gas-generation rates for both corrosion and biodegradation under inundated conditions, and the permeability of the long-term shaft seal.« less

  18. Mechanical and thermomechanical calculations related to the storage of spent nuclear-fuel assemblies in granite

    NASA Astrophysics Data System (ADS)

    Butkovich, T. R.

    1981-08-01

    A generic test of the geologic storage of spent-fuel assemblies from an operating nuclear reactor is being made by the Lawrence Livermore National Laboratory at the US Department of Energy's Nevada Test Site. The spent-fuel assemblies were emplaced at a depth of 420 m (1370 ft) below the surface in a typical granite and will be retrieved at a later time. The early time, close-in thermal history of this type of repository is being simulated with spent-fuel and electrically heated canisters in a central drift, with auxiliary heaters in two parallel side drifts. Prior to emplacement of the spent-fuel canister, preliminary calculations were made using a pair of existing finite-element codes. Calculational modeling of a spent-fuel repository requires a code with a multiple capability. The effects of both the mining operation and the thermal load on the existing stress fields and the resultant displacements of the rock around the repository must be calculated. The thermal loading for each point in the rock is affected by heat transfer through conduction, radiation, and normal convection, as well as by ventilation of the drifts. Both the ADINA stress code and the compatible ADINAT heat-flow code were used to perform the calculations because they satisfied the requirements of this project. ADINAT was adapted to calculate radiative and convective heat transfer across the drifts and to model the effects of ventilation in the drifts, while the existing isotropic elastic model was used with the ADINA code. The results of the calculation are intended to provide a base with which to compare temperature, stress, and displacement data taken during the planned 5-y duration of the test. In this way, it will be possible to determine how the existing jointing in the rock influences the results as compared with a homogeneous, isotropic rock mass. Later, new models will be introduced into ADINA to account for the effects of jointing.

  19. Yucca Mountain Project Subsurface Facilities Design

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    A. Linden; R.S. Saunders; R.J. Boutin

    2002-11-19

    Four units of the Topopah Springs formation (volcanic tuff) are considered for the proposed repository: the upper lithophysal, the middle non-lithophysal, the lower lithophysal, and the lower non-lithophysal. Yucca Mountain was recently designated the site for a proposed repository to dispose of spent nuclear fuel and high-level radioactive waste. Work is proceeding to advance the design of subsurface facilities to accommodate emplacing waste packages in the proposed repository. This paper summarized recent progress in the design of subsurface layout of the proposed repository. The original Site Recommendation (SR) concept for the subsurface design located the repository largely within the lowermore » lithophysal zone (approximately 73%) of the Topopah The Site Recommendation characterized area suitable for emplacement consisted of the primary upper block, the lower block and the southern upper block extension. The primary upper block accommodated the mandated 70,000 metric tons of heavy metal (MTHM) at a 1.45 kW/m hear heat load. Based on further study of the Site Recommendation concept, the proposed repository siting area footprint was modified to make maximum use of available site characterization data, and thus, reduce uncertainties associated with performance assessment. As a result of this study, a modified repository footprint has been proposed and is presently being review for acceptance by the DOE. A panel design concept was developed to reduce overall costs and reduce the overall emplacement schedule. This concept provides flexibility to adjust the proposed repository subsurface layout with time, as it makes it unnecessary to ''commit'' to development of a large single panel at the earliest stages of construction. A description of the underground layout configuration and influencing factors that affect the layout configuration are discussed in the report.« less

  20. 3D numerical modelling of the thermal state of deep geological nuclear waste repositories

    NASA Astrophysics Data System (ADS)

    Butov, R. A.; Drobyshevsky, N. I.; Moiseenko, E. V.; Tokarev, Yu. N.

    2017-09-01

    One of the important aspects of the high-level radioactive waste (HLW) disposal in deep geological repositories is ensuring the integrity of the engineered barriers which is, among other phenomena, considerably influenced by the thermal loads. As the HLW produce significant amount of heat, the design of the repository should maintain the balance between the cost-effectiveness of the construction and the sufficiency of the safety margins, including those imposed on the thermal conditions of the barriers. The 3D finite-element computer code FENIA was developed as a tool for simulation of thermal processes in deep geological repositories. Further the models for mechanical phenomena and groundwater hydraulics will be added resulting in a fully coupled thermo-hydro-mechanical (THM) solution. The long-term simulations of the thermal state were performed for two possible layouts of the repository. One was based on the proposed project of Russian repository, and another features larger HLW amount within the same space. The obtained results describe the spatial and temporal evolution of the temperature filed inside the repository and in the surrounding rock for 3500 years. These results show that practically all generated heat was ultimately absorbed by the host rock without any significant temperature increase. Still in the short time span even in case of smaller amount of the HLW the temperature maximum exceeds 100 °C, and for larger amount of the HLW the local temperature remains above 100 °C for considerable time. Thus, the substantiation of the long-term stability of the repository would require an extensive study of the materials properties and behaviour in order to remove the excessive conservatism from the simulations and to reduce the uncertainty of the input data.

  1. Simulation of fluid flow and energy transport processes associated with high-level radioactive waste disposal in unsaturated alluvium

    USGS Publications Warehouse

    Pollock, David W.

    1986-01-01

    Many parts of the Great Basin have thick zones of unsaturated alluvium which might be suitable for disposing of high-level radioactive wastes. A mathematical model accounting for the coupled transport of energy, water (vapor and liquid), and dry air was used to analyze one-dimensional, vertical transport above and below an areally extensive repository. Numerical simulations were conducted for a hypothetical repository containing spent nuclear fuel and located 100 m below land surface. Initial steady state downward water fluxes of zero (hydrostatic) and 0.0003 m yr−1were considered in an attempt to bracket the likely range in natural water flux. Predicted temperatures within the repository peaked after approximately 50 years and declined slowly thereafter in response to the decreasing intensity of the radioactive heat source. The alluvium near the repository experienced a cycle of drying and rewetting in both cases. The extent of the dry zone was strongly controlled by the mobility of liquid water near the repository under natural conditions. In the case of initial hydrostatic conditions, the dry zone extended approximately 10 m above and 15 m below the repository. For the case of a natural flux of 0.0003 m yr−1 the relative permeability of water near the repository was initially more than 30 times the value under hydrostatic conditions, consequently the dry zone extended only about 2 m above and 5 m below the repository. In both cases a significant perturbation in liquid saturation levels persisted for several hundred years. This analysis illustrates the extreme sensitivity of model predictions to initial conditions and parameters, such as relative permeability and moisture characteristic curves, that are often poorly known.

  2. Audit of a Scientific Data Center for Certification as a Trustworthy Digital Repository: A Case Study

    NASA Astrophysics Data System (ADS)

    Downs, R. R.; Chen, R. S.

    2011-12-01

    Services that preserve and enable future access to scientific data are necessary to ensure that the data that are being collected today will be available for use by future generations of scientists. Many data centers, archives, and other digital repositories are working to improve their ability to serve as long-term stewards of scientific data. Trust in sustainable data management and preservation capabilities of digital repositories can influence decisions to use these services to deposit or obtain scientific data. Building on the Open Archival Information System (OAIS) Reference Model developed by the Consultative Committee for Space Data Systems (CCSDS) and adopted by the International Organization for Standardization as ISO 14721:2003, new standards are being developed to improve long-term data management processes and documentation. The Draft Information Standard ISO/DIS 16363, "Space data and information transfer systems - Audit and certification of trustworthy digital repositories" offers the potential to evaluate digital repositories objectively in terms of their trustworthiness as long-term stewards of digital resources. In conjunction with this, the CCSDS and ISO are developing another draft standard for the auditing and certification process, ISO/DIS 16919, "Space data and information transfer systems - Requirements for bodies providing audit and certification of candidate trustworthy digital repositories". Six test audits were conducted of scientific data centers and archives in Europe and the United States to test the use of these draft standards and identify potential improvements for the standards and for the participating digital repositories. We present a case study of the test audit conducted on the NASA Socioeconomic Data and Applications Center (SEDAC) and describe the preparation, the audit process, recommendations received, and next steps to obtain certification as a trustworthy digital repository, after approval of the ISO/DIS standards.

  3. Corrosion behaviour of steel rebars embedded in a concrete designed for the construction of an intermediate-level radioactive waste disposal facility

    NASA Astrophysics Data System (ADS)

    Duffó, G. S.; Arva, E. A.; Schulz, F. M.; Vazquez, D. R.

    2013-07-01

    The National Atomic Energy Commission of the Argentine Republic is developing a nuclear waste disposal management programme that contemplates the design and construction of a facility for the final disposal of intermediate-level radioactive wastes. The repository is based on the use of multiple, independent and redundant barriers. The major components are made in reinforced concrete so, the durability of these structures is an important aspect for the facility integrity. This work presents an investigation performed on an instrumented reinforced concrete prototype specifically designed for this purpose, to study the behaviour of an intermediate level radioactive waste disposal facility from the rebar corrosion point of view. The information obtained will be used for the final design of the facility in order to guarantee a service life more or equal than the foreseen durability for this type of facilities.

  4. Preliminary access routes and cost study analyses for seven potentially acceptable salt sites: Final report, October 1984

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1987-02-01

    This report analyzes highway and railroad access to seven potentially acceptable salt repository sites: Richton Dome and Cypress Creek Dome in Mississippi, Vacherie Dome in Louisiana, Swisher County and Deaf Smith County in Texas, and Davis Canyon and Lavender Canyon in utah. The objectives of the study were to investigate the routing of reasonable access corridors to the sites, describe major characteristics of each route, and estimate the costs for constructing or upgrading highways and railroads. The routes used in the analysis are not necessarily recommended or preferred over other routes, nor do they represent an implied final selection. Detailedmore » engineering studies must be performed for the Davis Canyon and Lavender Canyon highway access before the analyzed routes can be considered to be viable. 20 refs., 7 figs., 3 tabs.« less

  5. Serial interpolation for secure membership testing and matching in a secret-split archive

    DOEpatents

    Kroeger, Thomas M.; Benson, Thomas R.

    2016-12-06

    The various technologies presented herein relate to analyzing a plurality of shares stored at a plurality of repositories to determine whether a secret from which the shares were formed matches a term in a query. A threshold number of shares are formed with a generating polynomial operating on the secret. A process of serially interpolating the threshold number of shares can be conducted whereby a contribution of a first share is determined, a contribution of a second share is determined while seeded with the contribution of the first share, etc. A value of a final share in the threshold number of shares can be determined and compared with the search term. In the event of the value of the final share and the search term matching, the search term matches the secret in the file from which the shares are formed.

  6. Durability of a reinforced concrete designed for the construction of an intermediate-level radioactive waste disposal facility

    NASA Astrophysics Data System (ADS)

    Duffó, G. S.; Arva, E. A.; Schulz, F. M.; Vazquez, D. R.

    2012-01-01

    The National Atomic Energy Commission of the Argentine Republic is developing a nuclear waste disposal management programme that contemplates the design and construction of a facility for the final disposal of intermediate-level radioactive wastes. The repository is based on the use of multiple, independent and redundant barriers. The major components are made in reinforced concrete so, the durability of these structures is an important aspect for the facility integrity. This work presents an investigation performed on a reinforced concrete specifically designed for this purpose, to predict the service life of the intermediate level radioactive waste disposal facility from data obtained with several techniques. Results obtained with corrosion sensors embedded in a concrete prototype are also included. The information obtained will be used for the final design of the facility in order to guarantee a service life more or equal than the foreseen durability for this type of facilities.

  7. The expert explorer: a tool for hospital data visualization and adverse drug event rules validation.

    PubMed

    Băceanu, Adrian; Atasiei, Ionuţ; Chazard, Emmanuel; Leroy, Nicolas

    2009-01-01

    An important part of adverse drug events (ADEs) detection is the validation of the clinical cases and the assessment of the decision rules to detect ADEs. For that purpose, a software called "Expert Explorer" has been designed by Ideea Advertising. Anonymized datasets have been extracted from hospitals into a common repository. The tool has 3 main features. (1) It can display hospital stays in a visual and comprehensive way (diagnoses, drugs, lab results, etc.) using tables and pretty charts. (2) It allows designing and executing dashboards in order to generate knowledge about ADEs. (3) It finally allows uploading decision rules obtained from data mining. Experts can then review the rules, the hospital stays that match the rules, and finally give their advice thanks to specialized forms. Then the rules can be validated, invalidated, or improved (knowledge elicitation phase).

  8. Uncertainty and sensitivity analysis for two-phase flow in the vicinity of the repository in the 1996 performance assessment for the Waste Isolation Pilot Plant: Undisturbed conditions

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    HELTON,JON CRAIG; BEAN,J.E.; ECONOMY,K.

    2000-05-19

    Uncertainty and sensitivity analysis results obtained in the 1996 performance assessment for the Waste Isolation Pilot Plant are presented for two-phase flow the vicinity of the repository under undisturbed conditions. Techniques based on Latin hypercube sampling, examination of scatterplots, stepwise regression analysis, partial correlation analysis and rank transformation are used to investigate brine inflow, gas generation repository pressure, brine saturation and brine and gas outflow. Of the variables under study, repository pressure is potentially the most important due to its influence on spallings and direct brine releases, with the uncertainty in its value being dominated by the extent to whichmore » the microbial degradation of cellulose takes place, the rate at which the corrosion of steel takes place, and the amount of brine that drains from the surrounding disturbed rock zone into the repository.« less

  9. Managing the nation`s nuclear waste. Site descriptions: Cypress Creek, Davis Canyon, Deaf Smith, Hanford Reference, Lavender Canyon, Richton Dome, Swisher, Vacherie Dome, and Yucca Mountain

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    1985-12-31

    In 1982, the Congress enacted the Nuclear Waste Policy Act (Public Law 97-425), which established a comprehensive national program directed toward siting, constructing, and operating geologic repositories for the permanent disposal of high-level radioactive waste. In February 1983, the United States Department of Energy (DOE) identified the nine referenced repository locations as potentially acceptable sites for a mined geologic repository. These sites have been evaluated in accordance with the DOE`s General Guidelines for the Recommendation of Sites for Nuclear Waste Repositories. The DOE findings and determinations are based on the evaluations contained in the draft Environmental Assessments (EA). A finalmore » EA will be prepared after considering the comments received on the draft EA. The purpose of this document is to provide the public with specific site information on each potential repository location.« less

  10. An ontology based information system for the management of institutional repository's collections

    NASA Astrophysics Data System (ADS)

    Tsolakidis, A.; Kakoulidis, P.; Skourlas, C.

    2015-02-01

    In this paper we discuss a simple methodological approach to create, and customize institutional repositories for the domain of the technological education. The use of the open source software platform of DSpace is proposed to build up the repository application and provide access to digital resources including research papers, dissertations, administrative documents, educational material, etc. Also the use of owl ontologies is proposed for indexing and accessing the various, heterogeneous items stored in the repository. Customization and operation of a platform for the selection and use of terms or parts of similar existing owl ontologies is also described. This platform could be based on the open source software Protégé that supports owl, is widely used, and also supports visualization, SPARQL etc. The combined use of the owl platform and the DSpace repository form a basis for creating customized ontologies, accommodating the semantic metadata of items and facilitating searching.

  11. Large-Scale In-situ Experiments to Determine Geochemical Alterations and Microbial Activities at the Geological Repository

    NASA Astrophysics Data System (ADS)

    Choung, S.; Francis, A. J.; Um, W.; Choi, S.; Kim, S.; Park, J.; Kim, S.

    2013-12-01

    The countries that have generated nuclear power have facing problems on the disposal of accumulated radioactive wastes. Geological disposal method has been chosen in many countries including Korea. A safety issue after the closure of geological repository has been raised, because microbial activities lead overpressure in the underground facilities through gas production. In particular, biodegradable organic materials derived from low- and intermediate-level radioactive wastes play important role on microbial activities in the geological repository. This study performed large scale in-situ experiments using organic wastes and groundwater, and investigated geochemical alteration and microbial activities at early stage (~63 days) as representative of the period, after closure of the geological repository. The geochemical alteration controlled significantly the microorganism types and populations. Database of the biogeochemical alteration facilitates prediction of radionuclides' mobility and establishment of remedial strategy against unpredictable accidents and hazards at early stage right after closure of the geological repository.

  12. Disposal of high-level nuclear waste above the water table in arid regions

    USGS Publications Warehouse

    Roseboom, Eugene H.

    1983-01-01

    Locating a repository in the unsaturated zone of arid regions eliminates or simplifies many of the technological problems involved in designing a repository for operation below the water table and predicting its performance. It also offers possible accessibility and ease of monitoring throughout the operational period and possible retrieval of waste long after. The risks inherent in such a repository appear to be no greater than in one located in the saturated zone; in fact, many aspects of such a repository's performance will be much easier to predict and the uncertainties will be reduced correspondingly. A major new concern would be whether future climatic changes could produce significant consequences due to possible rise of the water table or increased flux of water through the repository. If spent fuel were used as a waste form, a second new concern would be the rates of escape of gaseous iodine-129 and carbon-14 to the atmosphere.

  13. Potential Future Igneous Activity at Yucca Mountain, Nevada

    NASA Astrophysics Data System (ADS)

    Cline, M.; Perry, F. V.; Valentine, G. A.; Smistad, E.

    2005-12-01

    Location, timing, and volumes of post-Miocene volcanic activity, along with expert judgement, provide the basis for assessing the probability of future volcanism intersecting a proposed repository for nuclear waste at Yucca Mountain, Nevada. Analog studies of eruptive centers in the region that may represent the style and extent of possible future igneous activity at Yucca Mountain have aided in defining the consequence scenarios for intrusion into and eruption through a proposed repository. Modeling of magmatic processes related to magma/proposed repository interactions has been used to assess the potential consequences of a future igneous event through a proposed repository at Yucca Mountain. Results of work to date indicate future igneous activity in the Yucca Mountain region has a very low probability of intersecting the proposed repository. Probability of a future event intersecting a proposed repository at Yucca Mountain is approximately 1.7 X 10-8 per year. Since completion of the Probabilistic Volcanic Hazard Assessment (PVHA) in 1996, anomalies representing potential buried volcanic centers have been identified from aeromagnetic surveys. A re-assessment of the hazard is currently underway to evaluate the probability of intersection in light of new information and to estimate the probability of one or more volcanic conduits located in the proposed repository along a dike that intersects the proposed repository. U.S. Nuclear Regulatory Commission regulations for siting and licensing a proposed repository require that the consequences of a disruptive event (igneous event) with annual probability greater than 1 X 10-8 be evaluated. Two consequence scenarios are considered; 1) igneous intrusion-groundwater transport case and 2) volcanic eruptive case. These scenarios equate to a dike or dike swarm intersecting repository drifts containing waste packages, formation of a conduit leading to a volcanic eruption through the repository that carries the contents of the waste packages into the atmosphere, deposition of a tephra sheet, and redistribution of the contaminated ash. In both cases radioactive material is released to the accessible environment either through groundwater transport or through the atmospheric dispersal and deposition. Six Quaternary volcanic centers exist within 20 km of Yucca Mountain. Lathrop Wells cone (LWC), the youngest (approximately 75,000 yrs), is a well-preserved cinder cone with associated flows and tephra sheet that provides an excellent analogue for consequence studies related to future volcanism. Cone, lavas, hydrovolcanic ash, and ash-fall tephra have been examined to estimate eruptive volume and eruption type. LWC ejecta volumes suggest basaltic volcanism may be waning in the Yucca Mountain region.. The eruptive products indicate a sequence of initial fissure fountaining, early Strombolian ash and lapilli deposition forming the scoria cone, a brief hydrovolcanic pulse (possibly limited to the NW sector), and a violent Strombolian phase. Mathematical models have been developed to represent magmatic processes and their consequences on proposed repository performance. These models address dike propagation, magma interaction and flow into drifts, eruption through the proposed repository, and post intrusion/eruption effects. These models continue to be refined to reduce the uncertainty associated with the consequences from a possible future igneous event.

  14. 10 CFR Appendix II to Part 960 - NRC and EPA Requirements for Preclosure Repository Performance

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 4 2012-01-01 2012-01-01 false NRC and EPA Requirements for Preclosure Repository Performance II Appendix II to Part 960 Energy DEPARTMENT OF ENERGY GENERAL GUIDELINES FOR THE PRELIMINARY SCREENING OF POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY Pt. 960, App. II Appendix II to Part 960—NRC and...

  15. 10 CFR Appendix II to Part 960 - NRC and EPA Requirements for Preclosure Repository Performance

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 4 2011-01-01 2011-01-01 false NRC and EPA Requirements for Preclosure Repository Performance II Appendix II to Part 960 Energy DEPARTMENT OF ENERGY GENERAL GUIDELINES FOR THE PRELIMINARY SCREENING OF POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY Pt. 960, App. II Appendix II to Part 960—NRC and...

  16. 10 CFR Appendix II to Part 960 - NRC and EPA Requirements for Preclosure Repository Performance

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 4 2013-01-01 2013-01-01 false NRC and EPA Requirements for Preclosure Repository Performance II Appendix II to Part 960 Energy DEPARTMENT OF ENERGY GENERAL GUIDELINES FOR THE PRELIMINARY SCREENING OF POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY Pt. 960, App. II Appendix II to Part 960—NRC and...

  17. 10 CFR Appendix I to Part 960 - NRC and EPA Requirements for Postclosure Repository Performance

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 4 2013-01-01 2013-01-01 false NRC and EPA Requirements for Postclosure Repository Performance I Appendix I to Part 960 Energy DEPARTMENT OF ENERGY GENERAL GUIDELINES FOR THE PRELIMINARY SCREENING OF POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY Pt. 960, App. I Appendix I to Part 960—NRC and...

  18. 10 CFR Appendix II to Part 960 - NRC and EPA Requirements for Preclosure Repository Performance

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 4 2014-01-01 2014-01-01 false NRC and EPA Requirements for Preclosure Repository Performance II Appendix II to Part 960 Energy DEPARTMENT OF ENERGY GENERAL GUIDELINES FOR THE PRELIMINARY SCREENING OF POTENTIAL SITES FOR A NUCLEAR WASTE REPOSITORY Pt. 960, App. II Appendix II to Part 960—NRC and...

  19. If SWORD Is the Answer, What Is the Question?: Use of the Simple Web-Service Offering Repository Deposit Protocol

    ERIC Educational Resources Information Center

    Lewis, Stuart; Hayes, Leonie; Newton-Wade, Vanessa; Corfield, Antony; Davis, Richard; Donohue, Tim; Wilson, Scott

    2009-01-01

    Purpose: The purpose of this paper is to describe the repository deposit protocol, Simple Web-service Offering Repository Deposit (SWORD), its development iteration, and some of its potential use cases. In addition, seven case studies of institutional use of SWORD are provided. Design/methodology/approach: The paper describes the recent…

  20. Personal Spaces in Public Repositories as a Facilitator for Open Educational Resource Usage

    ERIC Educational Resources Information Center

    Cohen, Anat; Reisman, Sorel; Sperling, Barbra Bied

    2015-01-01

    Learning object repositories are a shared, open and public space; however, the possibility and ability of personal expression in an open, global, public space is crucial. The aim of this study is to explore personal spaces in a big learning object repository as a facilitator for adoption of Open Educational Resources (OER) into teaching practices…

  1. Making the Most of What We Have Got: Enhancing the RADAR Repository to Support Research Planning

    ERIC Educational Resources Information Center

    Pike, Dawn; Siminson, Nicola Jane

    2017-01-01

    This article discusses how RADAR, the institutional repository (IR) at the Glasgow School of Art (GSA), has been modified to house an Annual Research Planning (ARP) template. A case study on the implementation of this research planning tool will outline the role that a repository and its staff can play in supporting individuals, enhancing…

  2. Crowdsourcing Content to Promote Community and Collection Development in Public Libraries

    ERIC Educational Resources Information Center

    Carr, Melissa Eleftherion

    2013-01-01

    With the Poetry Center at San Francisco State University, the author has begun to build an open-access digital repository for poetry chapbooks. The repository is essentially a chapbook exchange: a place for poets to share their current works. Users are invited to share their chapbooks via upload and as such gain access to the chapbook repository.…

  3. Development and Implementation of a Learning Object Repository for French Teaching and Learning: Issues and Promises

    ERIC Educational Resources Information Center

    Caws, Catherine

    2008-01-01

    This paper discusses issues surrounding the development of a learning object repository (FLORE) for teaching and learning French at the postsecondary level. An evaluation based on qualitative and quantitative data was set up in order to better assess how second-language (L2) students in French perceived the integration of this new repository into…

  4. Attitudes to the Rights and Rewards for Author Contributions to Repositories for Teaching and Learning

    ERIC Educational Resources Information Center

    Bates, Melanie; Loddington, Steve; Manuel, Sue; Oppenheim, Charles

    2007-01-01

    In the United Kingdom over the past few years there has been a dramatic growth of national and regional repositories to collect and disseminate resources related to teaching and learning. Most notable of these are the Joint Information Systems Committee's Online Repository for [Learning and Teaching] Materials as well as the Higher Education…

  5. Institutional Repositories in the UK: What Can the Google User Find There?

    ERIC Educational Resources Information Center

    Markland, Margaret

    2006-01-01

    This study investigates the efficiency of the Google search engine at retrieving items from 26 UK Institutional Repositories, covering a wide range of subject areas. One item is chosen from each repository and four searches are carried out: two keyword searches and two full title searches, each using both Google and then Google Scholar. A further…

  6. Centralized mouse repositories.

    PubMed

    Donahue, Leah Rae; Hrabe de Angelis, Martin; Hagn, Michael; Franklin, Craig; Lloyd, K C Kent; Magnuson, Terry; McKerlie, Colin; Nakagata, Naomi; Obata, Yuichi; Read, Stuart; Wurst, Wolfgang; Hörlein, Andreas; Davisson, Muriel T

    2012-10-01

    Because the mouse is used so widely for biomedical research and the number of mouse models being generated is increasing rapidly, centralized repositories are essential if the valuable mouse strains and models that have been developed are to be securely preserved and fully exploited. Ensuring the ongoing availability of these mouse strains preserves the investment made in creating and characterizing them and creates a global resource of enormous value. The establishment of centralized mouse repositories around the world for distributing and archiving these resources has provided critical access to and preservation of these strains. This article describes the common and specialized activities provided by major mouse repositories around the world.

  7. Centralized Mouse Repositories

    PubMed Central

    Donahue, Leah Rae; de Angelis, Martin Hrabe; Hagn, Michael; Franklin, Craig; Lloyd, K. C. Kent; Magnuson, Terry; McKerlie, Colin; Nakagata, Naomi; Obata, Yuichi; Read, Stuart; Wurst, Wolfgang; Hörlein, Andreas; Davisson, Muriel T.

    2013-01-01

    Because the mouse is used so widely for biomedical research and the number of mouse models being generated is increasing rapidly, centralized repositories are essential if the valuable mouse strains and models that have been developed are to be securely preserved and fully exploited. Ensuring the ongoing availability of these mouse strains preserves the investment made in creating and characterizing them and creates a global resource of enormous value. The establishment of centralized mouse repositories around the world for distributing and archiving these resources has provided critical access to and preservation of these strains. This article describes the common and specialized activities provided by major mouse repositories around the world. PMID:22945696

  8. Digitizing dissertations for an institutional repository: a process and cost analysis.

    PubMed

    Piorun, Mary; Palmer, Lisa A

    2008-07-01

    This paper describes the Lamar Soutter Library's process and costs associated with digitizing 300 doctoral dissertations for a newly implemented institutional repository at the University of Massachusetts Medical School. Project tasks included identifying metadata elements, obtaining and tracking permissions, converting the dissertations to an electronic format, and coordinating workflow between library departments. Each dissertation was scanned, reviewed for quality control, enhanced with a table of contents, processed through an optical character recognition function, and added to the institutional repository. Three hundred and twenty dissertations were digitized and added to the repository for a cost of $23,562, or $0.28 per page. Seventy-four percent of the authors who were contacted (n = 282) granted permission to digitize their dissertations. Processing time per title was 170 minutes, for a total processing time of 906 hours. In the first 17 months, full-text dissertations in the collection were downloaded 17,555 times. Locally digitizing dissertations or other scholarly works for inclusion in institutional repositories can be cost effective, especially if small, defined projects are chosen. A successful project serves as an excellent recruitment strategy for the institutional repository and helps libraries build new relationships. Challenges include workflow, cost, policy development, and copyright permissions.

  9. A laboratory validation study of the time-lapse oscillatory pumping test for leakage detection in geological repositories

    NASA Astrophysics Data System (ADS)

    Sun, Alexander Y.; Lu, Jiemin; Islam, Akand

    2017-05-01

    Geologic repositories are extensively used for disposing byproducts in mineral and energy industries. The safety and reliability of these repositories are a primary concern to environmental regulators and the public. Time-lapse oscillatory pumping test (OPT) has been introduced recently as a pressure-based technique for detecting potential leakage in geologic repositories. By routinely conducting OPT at a number of pulsing frequencies, an operator may identify the potential repository anomalies in the frequency domain, alleviating the ambiguity caused by reservoir noise and improving the signal-to-noise ratio. Building on previous theoretical and field studies, this work performed a series of laboratory experiments to validate the concept of time-lapse OPT using a custom made, stainless steel tank under relatively high pressures. The experimental configuration simulates a miniature geologic storage repository consisting of three layers (i.e., injection zone, caprock, and above-zone aquifer). Results show that leakage in the injection zone led to deviations in the power spectrum of observed pressure data, and the amplitude of which also increases with decreasing pulsing frequencies. The experimental results are further analyzed by developing a 3D flow model, using which the model parameters are estimated through frequency domain inversion.

  10. Can Data Repositories Help Find Effective Treatments for Complex Diseases?

    PubMed Central

    Farber, Gregory K.

    2016-01-01

    There are many challenges to developing treatments for complex diseases. This review explores the question of whether it is possible to imagine a data repository that would increase the pace of understanding complex diseases sufficiently well to facilitate the development of effective treatments. First, consideration is given to the amount of data that might be needed for such a data repository and whether the existing data storage infrastructure is enough. Several successful data repositories are then examined to see if they have common characteristics. An area of science where unsuccessful attempts to develop a data infrastructure is then described to see what lessons could be learned for a data repository devoted to complex disease. Then, a variety of issues related to sharing data are discussed. In some of these areas, it is reasonably clear how to move forward. In other areas, there are significant open questions that need to be addressed by all data repositories. Using that baseline information, the question of whether data archives can be effective in understanding a complex disease is explored. The major goal of such a data archive is likely to be identifying biomarkers that define sub-populations of the disease. PMID:27018167

  11. Can data repositories help find effective treatments for complex diseases?

    PubMed

    Farber, Gregory K

    2017-05-01

    There are many challenges to developing treatments for complex diseases. This review explores the question of whether it is possible to imagine a data repository that would increase the pace of understanding complex diseases sufficiently well to facilitate the development of effective treatments. First, consideration is given to the amount of data that might be needed for such a data repository and whether the existing data storage infrastructure is enough. Several successful data repositories are then examined to see if they have common characteristics. An area of science where unsuccessful attempts to develop a data infrastructure is then described to see what lessons could be learned for a data repository devoted to complex disease. Then, a variety of issues related to sharing data are discussed. In some of these areas, it is reasonably clear how to move forward. In other areas, there are significant open questions that need to be addressed by all data repositories. Using that baseline information, the question of whether data archives can be effective in understanding a complex disease is explored. The major goal of such a data archive is likely to be identifying biomarkers that define sub-populations of the disease. Published by Elsevier Ltd.

  12. Integrating repositories with fuel cycles: The airport authority model

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Forsberg, C.

    2012-07-01

    The organization of the fuel cycle is a legacy of World War II and the cold war. Fuel cycle facilities were developed and deployed without consideration of the waste management implications. This led to the fuel cycle model of a geological repository site with a single owner, a single function (disposal), and no other facilities on site. Recent studies indicate large economic, safety, repository performance, nonproliferation, and institutional incentives to collocate and integrate all back-end facilities. Site functions could include geological disposal of spent nuclear fuel (SNF) with the option for future retrievability, disposal of other wastes, reprocessing with fuelmore » fabrication, radioisotope production, other facilities that generate significant radioactive wastes, SNF inspection (navy and commercial), and related services such as SNF safeguards equipment testing and training. This implies a site with multiple facilities with different owners sharing some facilities and using common facilities - the repository and SNF receiving. This requires a different repository site institutional structure. We propose development of repository site authorities modeled after airport authorities. Airport authorities manage airports with government-owned runways, collocated or shared public and private airline terminals, commercial and federal military facilities, aircraft maintenance bases, and related operations - all enabled and benefiting the high-value runway asset and access to it via taxi ways. With a repository site authority the high value asset is the repository. The SNF and HLW receiving and storage facilities (equivalent to the airport terminal) serve the repository, any future reprocessing plants, and others with needs for access to SNF and other wastes. Non-public special-built roadways and on-site rail lines (equivalent to taxi ways) connect facilities. Airport authorities are typically chartered by state governments and managed by commissions with members appointed by the state governor, county governments, and city governments. This structure (1) enables state and local governments to work together to maximize job and tax benefits to local communities and the state, (2) provides a mechanism to address local concerns such as airport noise, and (3) creates an institutional structure with large incentives to maximize the value of the common asset, the runway. A repository site authority would have a similar structure and be the local interface to any national waste management authority. (authors)« less

  13. Electrochemical behavior of Alloy 22 and friction type rock bolt

    NASA Astrophysics Data System (ADS)

    Rahman, Md Sazzadur

    Alloy 22 (Ni-22Cr-13Mo-3Fe-3W) is a candidate alloy for the outer shell of spent nuclear materials storage containers in the Yucca Mountain High Level Nuclear Waste Repository because of its excellent corrosion resistance. The nuclear waste container is cylindrical in shape and the end caps are welded. Typically, Alloy 22 retains the high temperature single phase cubic structure near room temperature, but topologically close packed (TCP) phases such as mu, P, sigma etc. and Cr rich carbides can form during thermal aging and welding. Rock bolts that are used for reinforcing subsurface tunnels are generally made of carbon or low alloy steels; these are being used in the nuclear repository tunnel. The corrosion behavior of these rock bolts have not been systematically evaluated under the environmental conditions of the repository. The ground waters at the Yucca Mountain (YM) repository permeate through the pores of the rock mass, and have propensity to corrode the rock bolts and waste package container. The environmental (aerated and deaerated) conditions influence the rate of corrosion in these material; these have not been systematically evaluated yet under the repository environment. In this study, the corrosion behavior of Alloy 22 and a friction type rock bolts was investigated as a function of temperature and concentration in complex multi-ionic electrolytes. Simulated electrolyte of YM ground water found in the repository environment was made in different concentrations (1X, 10X, and 100X). The interaction of simulated electrolytes in aerated and deaerated condition with Alloy 22 and low alloy steel of friction type rock bolt (split tapered cylinder type commercial design) has been investigated. Polarization resistance method was used to measure the corrosion rates. We found that the corrosion rate of Alloy 22 was higher in the deaerated electrolyte as compared to the aerated. The presence of oxygen in the electrolyte during aeration is conducive to formation of passive films that inhibits the corrosion process. The temperature dependency of the corrosion rate was affected by aeration and deaeration of the electrolytes. Another study related to corrosion behavior of weld Alloy 22 was undertaken to understand electrochemical behavior of welded structures. Corrosion studies were carried out in more aggressive electrolyte (0.1M HCl at 66°C) after solution annealing at 1121°C for 1 hr. In the as-welded structure a dendritic microstructure was observed in the weld region. However, after solution annealing these dendrites are not observed; suggesting homogenization of the grains. Three different specimens were made out from a welded Alloy 22 plates with large welded surface; weld interface, half weld and base metal away from the weld and heat affected zone, and corrosion rates of all these samples were measured. The results showed that the corrosion resistance of the solution annealed was higher in all three specimens than those of as-welded specimens. Corrosion rates of friction type set rock bolts (split set) were measured at 25°C, 45°C, 65°C and 90°C using 1X, 10X and 100X concentration of electrolyte both in aerated and deaerated conditions. The corrosion rates of rock bolts in 1X and 10X electrolyte showed ranged from ˜30 to 200mum/yr for deaerated and 150 to 1600 mum/yr for aerated. In summary, we have investigated the electrochemical behavior of the Alloy 22 and steels that have significance to the YM nuclear repository. The effects of temperature, type of electrolyte, condition of the alloys on the corrosion rates are reported.

  14. Airborne microorganisms cultivable on naturally ventilated document repositories of the National Archive of Cuba.

    PubMed

    Borrego, Sofía; Perdomo, Ivette

    2016-02-01

    The quality of the indoor air can provide very useful information for the artwork conservation. The aim of the study was to evaluate the microbial concentration inside six document repositories of the National Archive of the Republic of Cuba in two months of 1 year. The repositories are large, high, and have a natural cross-ventilation system. The microbial sampling was done in July 2010 (summer or rainy month) and February 2011 (winter or dry month) using the SAS Super 100 biocollector at 100 L/min. An appropriate selective culture media were used to isolate fungi and bacteria. A high total microbial concentration on the north side of the building in two studied months was observed. The fungal concentrations were significantly higher in July 2010 in all repositories, while the bacterial concentrations were significantly higher mostly in February 2011 only in repositories located on the first and second floor of the building. Eight fungal genera in the indoor air of all environments were isolated. Regardless of the side of the analyzed building, Penicillium, Aspergillus, and Cladosporium were the predominant genera. Aspergillus flavus and Aspergillus niger were the species isolated in almost all of the analyzed repositories in the studied months. Gram-positive bacteria prevailed among bacterial groups isolated from indoor air repositories, and some percentages corresponded to the genera Bacillus and Streptomyces. In Cuba, the temperature and relative humidity are high during the whole year but the natural ventilation plays an important role in retarding microbial growth on materials.

  15. Comparison of cardiac output optimization with an automated closed-loop goal-directed fluid therapy versus non standardized manual fluid administration during elective abdominal surgery: first prospective randomized controlled trial.

    PubMed

    Lilot, Marc; Bellon, Amandine; Gueugnon, Marine; Laplace, Marie-Christine; Baffeleuf, Bruno; Hacquard, Pauline; Barthomeuf, Felicie; Parent, Camille; Tran, Thomas; Soubirou, Jean-Luc; Robinson, Philip; Bouvet, Lionel; Vassal, Olivia; Lehot, Jean-Jacques; Piriou, Vincent

    2018-01-27

    An intraoperative automated closed-loop system for goal-directed fluid therapy has been successfully tested in silico, in vivo and in a clinical case-control matching. This trial compared intraoperative cardiac output (CO) in patients managed with this closed-loop system versus usual practice in an academic medical center. The closed-loop system was connected to a CO monitoring system and delivered automated colloid fluid boluses. Moderate to high-risk abdominal surgical patients were randomized either to the closed-loop or the manual group. Intraoperative final CO was the primary endpoint. Secondary endpoints were intraoperative overall mean cardiac index (CI), increase from initial to final CI, intraoperative fluid volume and postoperative outcomes. From January 2014 to November 2015, 46 patients were randomized. There was a lower initial CI (2.06 vs. 2.51 l min -1 m -2 , p = 0.042) in the closed-loop compared to the control group. No difference in final CO and in overall mean intraoperative CI was observed between groups. A significant relative increase from initial to final CI values was observed in the closed-loop but not the control group (+ 28.6%, p = 0.006 vs. + 1.2%, p = 0.843). No difference was found for intraoperative fluid management and postoperative outcomes between groups. There was no significant impact on the primary study endpoint, but this was found in a context of unexpected lower initial CI in the closed-loop group.Trial registry number ID-RCB/EudraCT: 2013-A00770-45. ClinicalTrials.gov Identifier NCT01950845, date of registration: 17 September 2013.

  16. The ROCTAPUS Closed-Circuit Television Program Final Report. Priority Country Area Program Evaluation Series: Report No. 10.

    ERIC Educational Resources Information Center

    Lamont, Ann; Fowler, Clifford F.

    Two 1980 surveys of school staff, team member interviews, and examination of project films and documents supplied information for final evaluation of the ROCTAPUS (Really Outstanding Color Television About Practically Unlimited Subjects) program, a closed-circuit, magazine format, videotaped, television series intended to enrich the experiential…

  17. 76 FR 23795 - Low-Power Television and Translator Upgrade Program: Notice of Final Closing Date

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-28

    .... 110418247-1247-01] Low-Power Television and Translator Upgrade Program: Notice of Final Closing Date AGENCY... receipt of applications for the Low-Power Television and Translator Upgrade Program (Upgrade Program) will... Rules to Establish Rules for Digital Low Power Television, Television Translator, and Television Booster...

  18. A successful search for hidden Barbarians in the Watsonia asteroid family

    NASA Astrophysics Data System (ADS)

    Cellino, A.; Bagnulo, S.; Tanga, P.; Novaković, B.; Delbò, M.

    2014-03-01

    Barbarians, so named after the prototype of this class (234) Barbara, are a rare class of asteroids exhibiting anomalous polarimetric properties. Their very distinctive feature is that they show negative polarization at relatively large phase angles, where all `normal' asteroids show positive polarization. The origin of the Barbarian phenomenon is unclear, but it seems to be correlated with the presence of anomalous abundances of spinel, a mineral usually associated with the so-called calcium-aluminium-rich inclusions (CAIs) on meteorites. Since CAIs are samples of the oldest solid matter identified in our Solar system, Barbarians are very interesting targets for investigations. Inspired by the fact that some of the few known Barbarians are members of, or very close to, the dynamical family of Watsonia, we have checked whether this family is a major repository of Barbarians, in order to obtain some hints about their possible collisional origin. We have measured the linear polarization of a sample of nine asteroids which are members of the Watsonia family within the phase-angle range 17°-21°. We found that seven of them exhibit the peculiar Barbarian polarization signature, and we conclude that the Watsonia family is a repository of Barbarian asteroids. The new Barbarians identified in our analysis will be important to confirm the possible link between the Barbarian phenomenon and the presence of spinel on the surface.

  19. Gas and water flow in an excavation-induced fracture network around an underground drift: A case study for a radioactive waste repository in clay rock

    NASA Astrophysics Data System (ADS)

    de La Vaissière, Rémi; Armand, Gilles; Talandier, Jean

    2015-02-01

    The Excavation Damaged Zone (EDZ) surrounding a drift, and in particular its evolution, is being studied for the performance assessment of a radioactive waste underground repository. A specific experiment (called CDZ) was designed and implemented in the Meuse/Haute-Marne Underground Research Laboratory (URL) in France to investigate the EDZ. This experiment is dedicated to study the evolution of the EDZ hydrogeological properties (conductivity and specific storage) of the Callovo-Oxfordian claystone under mechanical compression and artificial hydration. Firstly, a loading cycle applied on a drift wall was performed to simulate the compression effect from bentonite swelling in a repository drift (bentonite is a clay material to be used to seal drifts and shafts for repository closure purpose). Gas tests (permeability tests with nitrogen and tracer tests with helium) were conducted during the first phase of the experiment. The results showed that the fracture network within the EDZ was initially interconnected and opened for gas flow (particularly along the drift) and then progressively closed with the increasing mechanical stress applied on the drift wall. Moreover, the evolution of the EDZ after unloading indicated a self-sealing process. Secondly, the remaining fracture network was resaturated to demonstrate the ability to self-seal of the COx claystone without mechanical loading by conducting from 11 to 15 repetitive hydraulic tests with monitoring of the hydraulic parameters. During this hydration process, the EDZ effective transmissivity dropped due to the swelling of the clay materials near the fracture network. The hydraulic conductivity evolution was relatively fast during the first few days. Low conductivities ranging at 10-10 m/s were observed after four months. Conversely, the specific storage showed an erratic evolution during the first phase of hydration (up to 60 days). Some uncertainty remains on this parameter due to volumetric strain during the sealing of the fractures. The hydration was stopped after one year and cross-hole hydraulic tests were performed to determine more accurately the specific storage as well as the hydraulic conductivity at a meter-scale. All hydraulic conductivity values measured at the injection interval and at the observation intervals were all below 10-10 m/s. Moreover, the preferential inter-connectivity along the drift disappeared. Specific storage values at the observation and injection intervals were similar. Furthermore they were in agreement with the value obtained at the injection interval within the second hydration phase (60 days after starting hydration). The graphical abstract synthesizes the evolution of the hydraulic/gas conductivity for 8 intervals since the beginning of the CDZ experiment. The conductivity limit of 10-10 m/s corresponds to the lower bound hydraulic definition of the EDZ and it is demonstrated that EDZ can be sealed. This is a significant result in the demonstration of the long-term safety of a repository.

  20. The SoRReL papers: Recent publications of the Software Reuse Repository Lab

    NASA Technical Reports Server (NTRS)

    Eichmann, David A. (Editor)

    1992-01-01

    The entire publication is presented of some of the papers recently published by the SoRReL. Some typical titles are as follows: Design of a Lattice-Based Faceted Classification System; A Hybrid Approach to Software Reuse Repository Retrieval; Selecting Reusable Components Using Algebraic Specifications; Neural Network-Based Retrieval from Reuse Repositories; and A Neural Net-Based Approach to Software Metrics.

  1. Can Web 2.0 Enhance Community Participation in an Institutional Repository? The Case of PocketKnowledge at Teachers College, Columbia University

    ERIC Educational Resources Information Center

    Cocciolo, Anthony

    2010-01-01

    This project investigates if a Web 2.0 approach to designing an institutional repository can positively impact community participation. To study this, two institutional repositories (one Web 2.0, the other not) are used within the same institution. Results indicate that the use of a Web 2.0 approach significantly enhances community participation.…

  2. Engaging Researchers with the World's First Scholarly Arts Repositories: Ten Years after the UK's Kultur Project

    ERIC Educational Resources Information Center

    Meece, Stephanie; Robinson, Amy; Gramstadt, Marie-Therese

    2017-01-01

    Open access institutional repositories can be ill-equipped to manage the complexity of research outputs from departments of fine arts, media, drama, music, cultural heritage, and the creative arts in general. The U.K.-based Kultur project was funded to create a flexible multimedia repository model using EPrints software. The project launched the…

  3. Doing Your Science While You're in Orbit

    NASA Astrophysics Data System (ADS)

    Green, Mark L.; Miller, Stephen D.; Vazhkudai, Sudharshan S.; Trater, James R.

    2010-11-01

    Large-scale neutron facilities such as the Spallation Neutron Source (SNS) located at Oak Ridge National Laboratory need easy-to-use access to Department of Energy Leadership Computing Facilities and experiment repository data. The Orbiter thick- and thin-client and its supporting Service Oriented Architecture (SOA) based services (available at https://orbiter.sns.gov) consist of standards-based components that are reusable and extensible for accessing high performance computing, data and computational grid infrastructure, and cluster-based resources easily from a user configurable interface. The primary Orbiter system goals consist of (1) developing infrastructure for the creation and automation of virtual instrumentation experiment optimization, (2) developing user interfaces for thin- and thick-client access, (3) provide a prototype incorporating major instrument simulation packages, and (4) facilitate neutron science community access and collaboration. The secure Orbiter SOA authentication and authorization is achieved through the developed Virtual File System (VFS) services, which use Role-Based Access Control (RBAC) for data repository file access, thin-and thick-client functionality and application access, and computational job workflow management. The VFS Relational Database Management System (RDMS) consists of approximately 45 database tables describing 498 user accounts with 495 groups over 432,000 directories with 904,077 repository files. Over 59 million NeXus file metadata records are associated to the 12,800 unique NeXus file field/class names generated from the 52,824 repository NeXus files. Services that enable (a) summary dashboards of data repository status with Quality of Service (QoS) metrics, (b) data repository NeXus file field/class name full text search capabilities within a Google like interface, (c) fully functional RBAC browser for the read-only data repository and shared areas, (d) user/group defined and shared metadata for data repository files, (e) user, group, repository, and web 2.0 based global positioning with additional service capabilities are currently available. The SNS based Orbiter SOA integration progress with the Distributed Data Analysis for Neutron Scattering Experiments (DANSE) software development project is summarized with an emphasis on DANSE Central Services and the Virtual Neutron Facility (VNF). Additionally, the DANSE utilization of the Orbiter SOA authentication, authorization, and data transfer services best practice implementations are presented.

  4. Phase III: Implementation and Operation of the Repository

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None, None

    1998-07-01

    The metadata catalog was brought online for public access May 14, 1998. Since then dozens of users have registered and began to access the system. The system was demonstrated at the AAPG annual meeting in Salt Lake City and the EAGE (European Association of Geoscientists and Engineers) annual meeting in Leipzig, Germany. Hart Publications and PTTC "NetworkNews" have published articles about the metadata catalog, and articles for the AAPG Explorer and GSA Today are being developed. A back-up system at AGI headquarters was established. In support of the metadata catalog system, a leased-line Internet connection and two servers were installed.more » Porting of the GeoTrek server software to the new systems has begun. The back-up system will be operational during the 3 rd quarter of 1998 and will serve the NGDRS needs during periods when access to the site in Houston is down. Additionally, experimentation with new data types and deployment schemes will be tested on the system at AGI. The NGDRS has picked-up additional endorsements from the American Association of State Geologists, the MMS Outer Continental Shelf Policy Committee, and a new endorsement is being formulated by the AAPG Core Preservation Committee for consideration by the AAPG Executive Committee. The Texas Bureau of Economic Geology (BEG) is currently geocoding the well locations for the metadata catalog. Also, they have solicited proposals for the development of a core inventory control system that will work hand-in-hand with GeoTrek. A contract for that system will probably be given during the 3 rd quarter of 1998. The Texas Railroad Commission proposes to test the application of GeoTrek for accessing data in a joint project with the BEG. Several data transfer projects are underway. Vastar has committed to the transfer of 2D Appalachian seismic lines to the NDGRS clearinghouse. Receiving repositories have been identified and the final preparations are being made for transfer to these public repositories. Discussions have been initiated with the State of Oregon concerning listing their 400 oil and gas well and 50 geothermal well cores and logs on the metadata catalog. Additionally, discussions continue with the Stapleton Development Corporation concerning the transfer of facilities in Denver for use as a central core repository. A letter of intent for the facility's transfer is being reviewed.« less

  5. Diagnostic imaging learning resources evaluated by students and recent graduates.

    PubMed

    Alexander, Kate; Bélisle, Marilou; Dallaire, Sébastien; Fernandez, Nicolas; Doucet, Michèle

    2013-01-01

    Many learning resources can help students develop the problem-solving abilities and clinical skills required for diagnostic imaging. This study explored veterinary students' perceptions of the usefulness of a variety of learning resources. Perceived resource usefulness was measured for different levels of students and for academic versus clinical preparation. Third-year (n=139) and final (fifth) year (n=105) students and recent graduates (n=56) completed questionnaires on perceived usefulness of each resource. Resources were grouped for comparison: abstract/low complexity (e.g., notes, multimedia presentations), abstract/high complexity (e.g., Web-based and film case repositories), concrete/low complexity (e.g., large-group "clicker" workshops), and concrete/high complexity (e.g., small-group interpretation workshops). Lower-level students considered abstract/low-complexity resources more useful for academic preparation and concrete resources more useful for clinical preparation. Higher-level students/recent graduates also considered abstract/low-complexity resources more useful for academic preparation. For all levels, lecture notes were considered highly useful. Multimedia slideshows were an interactive complement to notes. The usefulness of a Web-based case repository was limited by accessibility problems and difficulty. Traditional abstract/low-complexity resources were considered useful for more levels and contexts than expected. Concrete/high-complexity resources need to better represent clinical practice to be considered more useful for clinical preparation.

  6. Studies concerning the durability of concrete vaults for intermediate level radioactive waste disposal: Electrochemical monitoring and corrosion aspects

    NASA Astrophysics Data System (ADS)

    Duffó, G. S.; Farina, S. B.; Arva, E. A.; Giordano, C. M.; Lafont, C. J.

    2006-11-01

    The Argentine Atomic Energy Commission (CNEA) is responsible of the development of a management nuclear waste disposal programme. This programme contemplates the design and construction of a facility for the final disposal of intermediate-level radioactive waste. The proposed concept is the near-surface monolithic repository similar to those in operation in El Cabril, Spain. The design of this type of repository is based on the use of multiple, independent and redundant barriers. Since the vault and cover are major components of the engineered barriers, the durability of these concrete structures is an important aspect for the facilities integrity. This work presents a laboratory and field investigation performed for the last 6 years on reinforced concrete specimens, in order to predict the service life of the intermediate level radioactive waste disposal vaults from data obtained from electrochemical techniques. On the other hand, the development of sensors that allow on-line measurements of rebar corrosion potential and corrosion current density; incoming oxygen flow that reaches the metal surface; concrete electrical resistivity and chloride concentration is shown. Those sensors, properly embedded in a new full scale vault (nowadays in construction), will allow the monitoring of the corrosion process of the steel rebars embedded in thestructure.

  7. Examination of Data Accession at the National Snow and Ice Data Center

    NASA Astrophysics Data System (ADS)

    Scott, D. J.; Booker, L.

    2017-12-01

    The National Snow and Ice Data Center (NSIDC) stewards nearly 750 publicly available snow and ice data sets that support research into our world's frozen realms. NSIDC data management is primarily supported by the National Aeronautics and Space Administration (NASA), the National Science Foundation (NSF) and the National Oceanic and Atmospheric Administration (NOAA), and most of the data we archive and distribute is assigned to NSIDC through the funding agency programs. In addition to these mandates, NSIDC has historically offered data stewardship to researchers wanting to properly preserve and increase visibility of their research data under our primary programs (NASA, NSF, NOAA). With publishers now requiring researchers to deliver data to a repository prior to the publication of their data-related papers, we have seen an increase in researcher-initiated data accession requests. This increase is pushing us to reexamine our process to ensure timeliness in the acquisition and release of these data. In this presentation, we will discuss the support and value a researcher receives by submitting data to a trustworthy repository. We will examine NSIDC's data accession practices, and the challenges of a consistent process across NSIDC's multiple funding sponsors. Finally, we will share recent activities related to improving our process and ideas we have for enhancing the overall data accession experience.

  8. Final environmental impact statement. Management of commercially generated radioactive waste. Volume 3. Public comments hearing board report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1980-10-01

    This EIS analyzes the significant environmental impacts that could occur if various technologies for management and disposal of high-level and transuranic wastes from commercial nuclear power reactors were to be developed and implemented. This EIS will serve as the environmental input for the decision on which technology, or technologies, will be emphasized in further research and development activities in the commercial waste management program. The action proposed in this EIS is to (1) adopt a national strategy to develop mined geologic repositories for disposal of commercially generated high-level and transuranic radioactive waste (while continuing to examine subseabed and very deepmore » hole disposal as potential backup technologies) and (2) conduct a R and D program to develop such facilities and the necessary technology to ensure the safe long-term containment and isolation of these wastes. The Department has considered in this statement: development of conventionally mined deep geologic repositories for disposal of spent fuel from nuclear power reactors and/or radioactive fuel reprocessing wastes; balanced development of several alternative disposal methods; and no waste disposal action. This volume contains written public comments and hearing board responses and reports offered on the draft statement.« less

  9. FY94 CAG trip reports, CAG memos and other products: Volume 2. Final report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    1994-12-15

    The Yucca Mountain Site Characterization Project (YMP) of the US DOE is tasked with designing, constructing, and operating an Exploratory Studies Facility (ESF) at Yucca Mountain, Nevada. The purpose of the YMP is to provide detailed characterization of the Yucca Mountain site for the potential mined geologic repository for permanent disposal of high-level radioactive waste. Detailed characterization of properties of the site are to be conducted through a wide variety of short-term and long-term in-situ tests. Testing methods require the installation of a large number of test instruments and sensors with a variety of functions. These instruments produce analog andmore » digital data that must be collected, processed, stored, and evaluated in an attempt to predict performance of the repository. The Integrated Data and Control System (IDCS) is envisioned as a distributed data acquisition that electronically acquires and stores data from these test instruments. IDCS designers are responsible for designing and overseeing the procurement of the system, IDCS Operation and Maintenance operates and maintains the installed system, and the IDCS Data Manager is responsible for distribution of IDCS data to participants. This report is a compilation of trip reports, interoffice memos, and other memos relevant to Computer Applications Group, Inc., work on this project.« less

  10. The ALICE Electronic Logbook

    NASA Astrophysics Data System (ADS)

    Altini, V.; Carena, F.; Carena, W.; Chapeland, S.; Chibante Barroso, V.; Costa, F.; Divià, R.; Fuchs, U.; Makhlyueva, I.; Roukoutakis, F.; Schossmaier, K.; Soòs, C.; Vande Vyvre, P.; Von Haller, B.; ALICE Collaboration

    2010-04-01

    All major experiments need tools that provide a way to keep a record of the events and activities, both during commissioning and operations. In ALICE (A Large Ion Collider Experiment) at CERN, this task is performed by the Alice Electronic Logbook (eLogbook), a custom-made application developed and maintained by the Data-Acquisition group (DAQ). Started as a statistics repository, the eLogbook has evolved to become not only a fully functional electronic logbook, but also a massive information repository used to store the conditions and statistics of the several online systems. It's currently used by more than 600 users in 30 different countries and it plays an important role in the daily ALICE collaboration activities. This paper will describe the LAMP (Linux, Apache, MySQL and PHP) based architecture of the eLogbook, the database schema and the relevance of the information stored in the eLogbook to the different ALICE actors, not only for near real time procedures but also for long term data-mining and analysis. It will also present the web interface, including the different used technologies, the implemented security measures and the current main features. Finally it will present the roadmap for the future, including a migration to the web 2.0 paradigm, the handling of the database ever-increasing data volume and the deployment of data-mining tools.

  11. Formulating a low-alkalinity, high-resistance and low-heat concrete for radioactive waste repositories

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cau Dit Coumes, Celine; Courtois, Simone; Nectoux, Didier

    2006-12-15

    Investigations were carried out in order to formulate and characterize low-alkalinity and low-heat cements which would be compatible with an underground waste repository environment. Several systems comprising Ordinary Portland Cement (OPC), a fast-reacting pozzolan (silica fume (SF) or metakaolin (MK)) and, in some cases, a slow-reacting product (fly ash (FA) or blastfurnace slag (BFS)) were compared. Promising results were obtained with some binary mixtures of OPC and SF, and with some ternary blends of OPC, SF and FA or BFS: pH of water in equilibrium with the fully hydrated cements dropped below 11. Dependence of the properties of standard mortarsmore » on the high contents of FA and SF in the low-pH blends was examined. Combining SF and FA seemed attractive since SF compensated for the low reactivity of FA, while FA allowed to reduce the water demand, and dimensional variations of the mortars. Finally, low-heat ({delta}T < 20 deg. C under semi-adiabatic conditions) and high strength ({approx} 70-80 MPa) concretes were prepared from two low-pH cements: a binary blend made from 60% of OPC and 40% of SF, and a ternary blend including 37.5% OPC, 32.5% SF and 30% FA.« less

  12. D Cultural Heritage Documentation: a Comparison Between Different Photogrammetric Software and Their Products

    NASA Astrophysics Data System (ADS)

    Gagliolo, S.; Ausonio, E.; Federici, B.; Ferrando, I.; Passoni, D.; Sguerso, D.

    2018-05-01

    The conservation of Cultural Heritage depends on the availability of means and resources and, consequently, on the possibility to make effective operations of data acquisition. In facts, on the one hand the creation of data repositories allows the description of the present state-of-art, in order to preserve the testimonial value and to permit the fruition. On the other hand, data acquisition grants a metrical knowledge, which is particularly useful for a direct restoration of the surveyed objects, through the analysis of their 3D digital models. In the last decades, the continuous increase and improvement of 3D survey techniques and of tools for the geometric and digital data management have represented a great support to the development of documentary activities. In particular, Photogrammetry is a survey technique highly appropriate in the creation of data repositories in the field of Cultural Heritage, thanks to its advantages of cheapness, flexibility, speed, and the opportunity to ensure the operators' safety in hazardous areas too. In order to obtain a complete documentation, the high precision of the on-site operations must be coupled with an effective post-processing phase. Hence, a comparison among some of the photogrammetric software currently available was performed by the authors, with a particular attention to the workflow completeness and the final products quality.

  13. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    Some of the major technical questions associated with the burial of radioactive high-level wastes in geologic formations are related to the thermal environments generated by the waste and the impact of this dissipated heat on the surrounding environment. The design of a high level waste storage facility must be such that the temperature variations that occur do not adversely affect operating personnel and equipment. The objective of this investigation was to assist OWI by determining the thermal environment that would be experienced by personnel and equipment in a waste storage facility in salt. Particular emphasis was placed on determining themore » maximum floor and air temperatures with and without ventilation in the first 30 years after waste emplacement. The assumed facility design differs somewhat from those previously analyzed and reported, but many of the previous parametric surveys are useful for comparison. In this investigation a number of 2-dimensional and 3-dimensional simulations of the heat flow in a repository have been performed on the HEATING5 and TRUMP heat transfer codes. The representative repository constructs used in the simulations are described, as well as the computational models and computer codes. Results of the simulations are presented and discussed. Comparisons are made between the recent results and those from previous analyses. Finally, a summary of study limitations, comparisons, and conclusions is given.« less

  14. PACOM: A Versatile Tool for Integrating, Filtering, Visualizing, and Comparing Multiple Large Mass Spectrometry Proteomics Data Sets.

    PubMed

    Martínez-Bartolomé, Salvador; Medina-Aunon, J Alberto; López-García, Miguel Ángel; González-Tejedo, Carmen; Prieto, Gorka; Navajas, Rosana; Salazar-Donate, Emilio; Fernández-Costa, Carolina; Yates, John R; Albar, Juan Pablo

    2018-04-06

    Mass-spectrometry-based proteomics has evolved into a high-throughput technology in which numerous large-scale data sets are generated from diverse analytical platforms. Furthermore, several scientific journals and funding agencies have emphasized the storage of proteomics data in public repositories to facilitate its evaluation, inspection, and reanalysis. (1) As a consequence, public proteomics data repositories are growing rapidly. However, tools are needed to integrate multiple proteomics data sets to compare different experimental features or to perform quality control analysis. Here, we present a new Java stand-alone tool, Proteomics Assay COMparator (PACOM), that is able to import, combine, and simultaneously compare numerous proteomics experiments to check the integrity of the proteomic data as well as verify data quality. With PACOM, the user can detect source of errors that may have been introduced in any step of a proteomics workflow and that influence the final results. Data sets can be easily compared and integrated, and data quality and reproducibility can be visually assessed through a rich set of graphical representations of proteomics data features as well as a wide variety of data filters. Its flexibility and easy-to-use interface make PACOM a unique tool for daily use in a proteomics laboratory. PACOM is available at https://github.com/smdb21/pacom .

  15. SATORI: a system for ontology-guided visual exploration of biomedical data repositories.

    PubMed

    Lekschas, Fritz; Gehlenborg, Nils

    2018-04-01

    The ever-increasing number of biomedical datasets provides tremendous opportunities for re-use but current data repositories provide limited means of exploration apart from text-based search. Ontological metadata annotations provide context by semantically relating datasets. Visualizing this rich network of relationships can improve the explorability of large data repositories and help researchers find datasets of interest. We developed SATORI-an integrative search and visual exploration interface for the exploration of biomedical data repositories. The design is informed by a requirements analysis through a series of semi-structured interviews. We evaluated the implementation of SATORI in a field study on a real-world data collection. SATORI enables researchers to seamlessly search, browse and semantically query data repositories via two visualizations that are highly interconnected with a powerful search interface. SATORI is an open-source web application, which is freely available at http://satori.refinery-platform.org and integrated into the Refinery Platform. nils@hms.harvard.edu. Supplementary data are available at Bioinformatics online.

  16. Geochemical Results of Lysimeter Sampling at the Manning Canyon Repository in the Mercur Mining District, Utah

    USGS Publications Warehouse

    Earle, John; Choate, LaDonna

    2010-01-01

    This report presents chemical characteristics of transient unsaturated-zone water collected by lysimeter from the Manning Canyon repository site in Utah. Data collected by U.S. Geological Survey and U.S. Department of the Interior, Bureau of Land Management scientists under an intragovernmental order comprise the existing body of hydrochemical information on unsaturated-zone conditions at the site and represent the first effort to characterize the chemistry of the soil pore water surrounding the repository. Analyzed samples showed elevated levels of arsenic, barium, chromium, and strontium, which are typical of acidic mine drainage. The range of major-ion concentrations generally showed expected soil values. Although subsequent sampling is necessary to determine long-term effects of the repository, current results provide initial data concerning reactive processes of precipitation on the mine tailings and waste rock stored at the site and provide information on the effectiveness of reclamation operations at the Manning Canyon repository.

  17. Assuring the Quality of Agricultural Learning Repositories: Issues for the Learning Object Metadata Creation Process of the CGIAR

    NASA Astrophysics Data System (ADS)

    Zschocke, Thomas; Beniest, Jan

    The Consultative Group on International Agricultural Re- search (CGIAR) has established a digital repository to share its teaching and learning resources along with descriptive educational information based on the IEEE Learning Object Metadata (LOM) standard. As a critical component of any digital repository, quality metadata are critical not only to enable users to find more easily the resources they require, but also for the operation and interoperability of the repository itself. Studies show that repositories have difficulties in obtaining good quality metadata from their contributors, especially when this process involves many different stakeholders as is the case with the CGIAR as an international organization. To address this issue the CGIAR began investigating the Open ECBCheck as well as the ISO/IEC 19796-1 standard to establish quality protocols for its training. The paper highlights the implications and challenges posed by strengthening the metadata creation workflow for disseminating learning objects of the CGIAR.

  18. DataONE: Gateway to Earth and Environmental Data Repositories

    NASA Astrophysics Data System (ADS)

    Koskela, R.; Michener, W. K.; Vieglais, D.; Budden, A. E.

    2017-12-01

    DataONE (Data Observation Network for Earth) is a National Science Foundation DataNet project that enables universal access to data and also facilitates researchers in fulfilling their need for data management and in providing secure and permanent access to their data. DataONE offers the scientific community a suite of tools and training materials that cover all aspects of the data life cycle from data collection, to management, analysis and publication. Data repositories affiliated with DataONE are referred to as Member Nodes and represent large regional, national and international research networks, agencies, and other institutions. As part of the DataONE Federation, the repositories gain access to a range of value-added services to support their users. These services include usage tracking and reporting, content replication, and the ability to register the services created by the repository. In addition, DataONE and the California Digital Library manage ONEShare, a repository that accepts content submitted through Dash, a platform allowing researchers to easily describe, deposit and share their research data.

  19. A Preliminary Performance Assessment for Salt Disposal of High-Level Nuclear Waste - 12173

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lee, Joon H.; Clayton, Daniel; Jove-Colon, Carlos

    2012-07-01

    A salt repository is one of the four geologic media currently under study by the U.S. DOE Office of Nuclear Energy to support the development of a long-term strategy for geologic disposal of commercial used nuclear fuel (UNF) and high-level radioactive waste (HLW). The immediate goal of the generic salt repository study is to develop the necessary modeling tools to evaluate and improve the understanding of the repository system response and processes relevant to long-term disposal of UNF and HLW in a salt formation. The current phase of this study considers representative geologic settings and features adopted from previous studiesmore » for salt repository sites. For the reference scenario, the brine flow rates in the repository and underlying interbeds are very low, and transport of radionuclides in the transport pathways is dominated by diffusion and greatly retarded by sorption on the interbed filling materials. I-129 is the dominant annual dose contributor at the hypothetical accessible environment, but the calculated mean annual dose is negligibly small. For the human intrusion (or disturbed) scenario, the mean mass release rate and mean annual dose histories are very different from those for the reference scenario. Actinides including Pu-239, Pu-242 and Np-237 are major annual dose contributors, and the calculated peak mean annual dose is acceptably low. A performance assessment model for a generic salt repository has been developed incorporating, where applicable, representative geologic settings and features adopted from literature data for salt repository sites. The conceptual model and scenario for radionuclide release and transport from a salt repository were developed utilizing literature data. The salt GDS model was developed in a probabilistic analysis framework. The preliminary performance analysis for demonstration of model capability is for an isothermal condition at the ambient temperature for the near field. The capability demonstration emphasizes key attributes of a salt repository that are potentially important to the long-term safe disposal of UNF and HLW. The analysis presents and discusses the results showing repository responses to different radionuclide release scenarios (undisturbed and human intrusion). For the reference (or nominal or undisturbed) scenario, the brine flow rates in the repository and underlying interbeds are very low, and transport of radionuclides in the transport pathways is dominated by diffusion and greatly retarded by sorption on the interbed filling materials. I-129 (non-sorbing and unlimited solubility with a very long half-life) is the dominant annual dose contributor at the hypothetical accessible environment, but the calculated mean annual dose is negligibly small that there is no meaningful consequence for the repository performance. For the human intrusion (or disturbed) scenario analysis, the mean mass release rate and mean annual dose histories are very different from those for the reference scenario analysis. Compared to the reference scenario, the relative annual dose contributions by soluble, non-sorbing fission products, particularly I-129, are much lower than by actinides including Pu-239, Pu-242 and Np-237. The lower relative mean annual dose contributions by the fission product radionuclides are due to their lower total inventory available for release (i.e., up to five affected waste packages), and the higher mean annual doses by the actinides are the outcome of the direct release of the radionuclides into the overlying aquifer having high water flow rates, thereby resulting in an early arrival of higher concentrations of the radionuclides at the biosphere drinking water well prior to their significant decay. The salt GDS model analysis has also identified the following future recommendations and/or knowledge gaps to improve and enhance the confidence of the future repository performance analysis. - Repository thermal loading by UNF and HLW, and the effect on the engineered barrier and near-field performance. - Closure and consolidation of salt rocks by creep deformation under the influence of thermal perturbation, and the effect on the engineered barrier and near-field performance. - Brine migration and radionuclide transport under the influence of thermal perturbation in generic salt repository environment, and the effect on the engineered barrier and near-field performance and far-field performance. - Near-field geochemistry and radionuclide mobility in generic salt repository environment (high ionic strength brines, elevated temperatures and chemically reducing condition). - Degradation of engineer barrier components (waste package, waste canister, waste forms, etc.) in a generic salt repository environment (high ionic strength brines, elevated temperatures and chemically reducing condition). - Waste stream types and inventory estimates, particularly for reprocessing high-level waste. (authors)« less

  20. The Geant4 physics validation repository

    NASA Astrophysics Data System (ADS)

    Wenzel, H.; Yarba, J.; Dotti, A.

    2015-12-01

    The Geant4 collaboration regularly performs validation and regression tests. The results are stored in a central repository and can be easily accessed via a web application. In this article we describe the Geant4 physics validation repository which consists of a relational database storing experimental data and Geant4 test results, a java API and a web application. The functionality of these components and the technology choices we made are also described.

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