46 CFR 308.533 - Closing report, Form MA-313.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 8 2014-10-01 2014-10-01 false Closing report, Form MA-313. 308.533 Section 308.533 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Cargo Insurance Open Policy War Risk Cargo Insurance § 308.533 Closing report, Form MA-313. This...

Closed-form dynamics of a hexarot parallel manipulator by means of the principle of virtual work

NASA Astrophysics Data System (ADS)

Pedrammehr, Siamak; Nahavandi, Saeid; Abdi, Hamid

2018-04-01

In this research, a systematic approach to solving the inverse dynamics of hexarot manipulators is addressed using the methodology of virtual work. For the first time, a closed form of the mathematical formulation of the standard dynamic model is presented for this class of mechanisms. An efficient algorithm for solving this closed-form dynamic model of the mechanism is developed and it is used to simulate the dynamics of the system for different trajectories. Validation of the proposed model is performed using SimMechanics and it is shown that the results of the proposed mathematical model match with the results obtained by the SimMechanics model.

A Closed-Form Error Model of Straight Lines for Improved Data Association and Sensor Fusing

PubMed Central

2018-01-01

Linear regression is a basic tool in mobile robotics, since it enables accurate estimation of straight lines from range-bearing scans or in digital images, which is a prerequisite for reliable data association and sensor fusing in the context of feature-based SLAM. This paper discusses, extends and compares existing algorithms for line fitting applicable also in the case of strong covariances between the coordinates at each single data point, which must not be neglected if range-bearing sensors are used. Besides, in particular, the determination of the covariance matrix is considered, which is required for stochastic modeling. The main contribution is a new error model of straight lines in closed form for calculating quickly and reliably the covariance matrix dependent on just a few comprehensible and easily-obtainable parameters. The model can be applied widely in any case when a line is fitted from a number of distinct points also without a priori knowledge of the specific measurement noise. By means of extensive simulations, the performance and robustness of the new model in comparison to existing approaches is shown. PMID:29673205

Analytic Closed-Form Solution of a Mixed Layer Model for Stratocumulus Clouds

NASA Astrophysics Data System (ADS)

Akyurek, Bengu Ozge

Stratocumulus clouds play an important role in climate cooling and are hard to predict using global climate and weather forecast models. Thus, previous studies in the literature use observations and numerical simulation tools, such as large-eddy simulation (LES), to solve the governing equations for the evolution of stratocumulus clouds. In contrast to the previous works, this work provides an analytic closed-form solution to the cloud thickness evolution of stratocumulus clouds in a mixed-layer model framework. With a focus on application over coastal lands, the diurnal cycle of cloud thickness and whether or not clouds dissipate are of particular interest. An analytic solution enables the sensitivity analysis of implicitly interdependent variables and extrema analysis of cloud variables that are hard to achieve using numerical solutions. In this work, the sensitivity of inversion height, cloud-base height, and cloud thickness with respect to initial and boundary conditions, such as Bowen ratio, subsidence, surface temperature, and initial inversion height, are studied. A critical initial cloud thickness value that can be dissipated pre- and post-sunrise is provided. Furthermore, an extrema analysis is provided to obtain the minima and maxima of the inversion height and cloud thickness within 24 h. The proposed solution is validated against LES results under the same initial and boundary conditions. Then, the proposed analytic framework is extended to incorporate multiple vertical columns that are coupled by advection through wind flow. This enables a bridge between the micro-scale and the mesoscale relations. The effect of advection on cloud evolution is studied and a sensitivity analysis is provided.

17 CFR 239.14 - Form N-2 for closed end management investment companies registered on Form N-8A.

Code of Federal Regulations, 2010 CFR

2010-04-01

... management investment companies registered on Form N-8A. 239.14 Section 239.14 Commodity and Securities... Registration Statements § 239.14 Form N-2 for closed end management investment companies registered on Form N... closed end management investment companies registered under the Investment Company Act of 1940 on form N...

Optimal Mortgage Refinancing: A Closed Form Solution.

PubMed

Agarwal, Sumit; Driscoll, John C; Laibson, David I

2013-06-01

We derive the first closed-form optimal refinancing rule: Refinance when the current mortgage interest rate falls below the original rate by at least [Formula: see text] In this formula W (.) is the Lambert W -function, [Formula: see text] ρ is the real discount rate, λ is the expected real rate of exogenous mortgage repayment, σ is the standard deviation of the mortgage rate, κ/M is the ratio of the tax-adjusted refinancing cost and the remaining mortgage value, and τ is the marginal tax rate. This expression is derived by solving a tractable class of refinancing problems. Our quantitative results closely match those reported by researchers using numerical methods.

Closed Forms for 4-Parameter Families of Integrals

ERIC Educational Resources Information Center

Dana-Picard, Thierry; Zeitoun, David G.

2009-01-01

We compute closed forms for two multiparameter families of definite integrals, thus obtaining combinatorial formulas. As a consequence, a surprising formula is derived between a definite integral and an improper integral for the same parametric function.

46 CFR 308.533 - Closing report, Form MA-313.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Cargo Insurance Ii-Open Policy War Risk Cargo Insurance § 308.533 Closing report, Form MA-313. This form, which may be obtained from the American War Risk Agency or MARAD, shall be filed in...

46 CFR 308.533 - Closing report, Form MA-313.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Cargo Insurance Ii-Open Policy War Risk Cargo Insurance § 308.533 Closing report, Form MA-313. This form, which may be obtained from the American War Risk Agency or MARAD, shall be filed in...

46 CFR 308.533 - Closing report, Form MA-313.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Cargo Insurance Ii-Open Policy War Risk Cargo Insurance § 308.533 Closing report, Form MA-313. This form, which may be obtained from the American War Risk Agency or MARAD, shall be filed in...

46 CFR 308.533 - Closing report, Form MA-313.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Cargo Insurance Ii-Open Policy War Risk Cargo Insurance § 308.533 Closing report, Form MA-313. This form, which may be obtained from the American War Risk Agency or MARAD, shall be filed in...

Nanoscale phase transition behavior of shape memory alloys — closed form solution of 1D effective modelling

NASA Astrophysics Data System (ADS)

Li, M. P.; Sun, Q. P.

2018-01-01

We investigate the roles of grain size (lg) and grain boundary thickness (lb) on the stress-induced phase transition (PT) behaviors of nanocrystalline shape memory alloys (SMAs) by using a Core-shell type "crystallite-amorphous composite" model. A non-dimensionalized length scale lbarg(=lg /lb) is identified as the governing parameter which is indicative of the energy competition between the crystallite and the grain boundary. Closed form analytical solutions of a reduced effective 1D model with embedded microstructure length scales of lg and lb are presented in this paper. It is shown that, with lbarg reduction, the energy of the elastic non-transformable grain boundary will gradually become dominant in the phase transition process, and eventually bring fundamental changes of the deformation behaviors: breakdown of two-phase coexistence and vanishing of superelastic hysteresis. The predictions are supported by experimental data of nanocrystalline NiTi SMAs.

Modeling of Filament Deposition Rapid Prototyping Process with a Closed form Solution

NASA Astrophysics Data System (ADS)

Devlin, Steven Leon

Fused Deposition Modeling (FDM(TM)) or fused filament fabrication (FFF) systems are extrusion-based technologies used to produce functional or near functional parts from a wide variety of plastic materials. First patented by S. Scott Crump and commercialized by Stratasys, Ltd in the early 1990s, this technology, like many additive manufacturing systems, offers significant opportunities for the design and production of complex part structures that are difficult if not impossible to produce using traditional manufacturing methods. Standing on the shoulders of a twenty-five year old invention, a rapidly growing open-source development community has exponentially driven interest in FFF technology. However, part quality often limits use in final product commercial markets. Development of accurate and repeatable methods for determining material strength in FFF produced parts is essential for wide adoption into mainstream manufacturing. This study builds on the empirical, squeeze flow and intermolecular diffusion model research conducted by David Grewell and Avraham Benatar, applying a combined model to predict auto adhesion or healing to FFF part samples. In this research, an experimental study and numerical modeling were performed in order to drive and validate a closed form heat transfer solution for extrusion processes to develop temperature field models. An extrusion-based 3D printing system, with the capacity to vary deposition speeds and temperatures, was used to fabricate the samples. Standardized specimens of Polylactic Acid (PLA) and Acrylonitrile Butadiene Styrene (ABS) filament were used to fabricate the samples with different speeds and temperatures. Micro-scanning of cut and lapped specimens, using an optical microscope, was performed to find the effect of the speed and the temperature on the geometry of the cross-sections. It was found that by increasing the speed of the extrusion printing, the area of the cross-section and the maximum thickness decrease

A model for closing the inviscid form of the average-passage equation system

NASA Technical Reports Server (NTRS)

Adamczyk, J. J.; Mulac, R. A.; Celestina, M. L.

1985-01-01

A mathematical model is proposed for closing or mathematically completing the system of equations which describes the time average flow field through the blade passages of multistage turbomachinery. These equations referred to as the average passage equation system govern a conceptual model which has proven useful in turbomachinery aerodynamic design and analysis. The closure model is developed so as to insure a consistency between these equations and the axisymmetric through flow equations. The closure model was incorporated into a computer code for use in simulating the flow field about a high speed counter rotating propeller and a high speed fan stage. Results from these simulations are presented.

Exact Closed-form Solutions for Lamb's Problem

NASA Astrophysics Data System (ADS)

Feng, Xi; Zhang, Haiming

2018-04-01

In this article, we report on an exact closed-form solution for the displacement at the surface of an elastic half-space elicited by a buried point source that acts at some point underneath that surface. This is commonly referred to as the 3-D Lamb's problem, for which previous solutions were restricted to sources and receivers placed at the free surface. By means of the reciprocity theorem, our solution should also be valid as a means to obtain the displacements at interior points when the source is placed at the free surface. We manage to obtain explicit results by expressing the solution in terms of elementary algebraic expression as well as elliptic integrals. We anchor our developments on Poisson's ratio 0.25 starting from Johnson's (1974) integral solutions which must be computed numerically. In the end, our closed-form results agree perfectly with the numerical results of Johnson (1974), which strongly confirms the correctness of our explicit formulas. It is hoped that in due time, these formulas may constitute a valuable canonical solution that will serve as a yardstick against which other numerical solutions can be compared and measured.

Exact closed-form solutions for Lamb's problem

NASA Astrophysics Data System (ADS)

Feng, Xi; Zhang, Haiming

2018-07-01

In this paper, we report on an exact closed-form solution for the displacement at the surface of an elastic half-space elicited by a buried point source that acts at some point underneath that surface. This is commonly referred to as the 3-D Lamb's problem for which previous solutions were restricted to sources and receivers placed at the free surface. By means of the reciprocity theorem, our solution should also be valid as a means to obtain the displacements at interior points when the source is placed at the free surface. We manage to obtain explicit results by expressing the solution in terms of elementary algebraic expression as well as elliptic integrals. We anchor our developments on Poisson's ratio 0.25 starting from Johnson's integral solutions which must be computed numerically. In the end, our closed-form results agree perfectly with the numerical results of Johnson, which strongly confirms the correctness of our explicit formulae. It is hoped that in due time, these formulae may constitute a valuable canonical solution that will serve as a yardstick against which other numerical solutions can be compared and measured.

Resolving the biophysics of axon transmembrane polarization in a single closed-form description

DOE Office of Scientific and Technical Information (OSTI.GOV)

Melendy, Robert F., E-mail: rfmelendy@liberty.edu

2015-12-28

When a depolarizing event occurs across a cell membrane there is a remarkable change in its electrical properties. A complete depolarization event produces a considerably rapid increase in voltage that propagates longitudinally along the axon and is accompanied by changes in axial conductance. A dynamically changing magnetic field is associated with the passage of the action potential down the axon. Over 75 years of research has gone into the quantification of this phenomenon. To date, no unified model exist that resolves transmembrane polarization in a closed-form description. Here, a simple but formative description of propagated signaling phenomena in the membranemore » of an axon is presented in closed-form. The focus is on using both biophysics and mathematical methods for elucidating the fundamental mechanisms governing transmembrane polarization. The results presented demonstrate how to resolve electromagnetic and thermodynamic factors that govern transmembrane potential. Computational results are supported by well-established quantitative descriptions of propagated signaling phenomena in the membrane of an axon. The findings demonstrate how intracellular conductance, the thermodynamics of magnetization, and current modulation function together in generating an action potential in a unified closed-form description. The work presented in this paper provides compelling evidence that three basic factors contribute to the propagated signaling in the membrane of an axon. It is anticipated this work will compel those in biophysics, physical biology, and in the computational neurosciences to probe deeper into the classical and quantum features of membrane magnetization and signaling. It is hoped that subsequent investigations of this sort will be advanced by the computational features of this model without having to resort to numerical methods of analysis.« less

On computing closed forms for summations. [polynomials and rational functions

NASA Technical Reports Server (NTRS)

Moenck, R.

1977-01-01

The problem of finding closed forms for a summation involving polynomials and rational functions is considered. A method closely related to Hermite's method for integration of rational functions derived. The method expresses the sum of a rational function as a rational function part and a transcendental part involving derivatives of the gamma function.

Optimal Mortgage Refinancing: A Closed Form Solution

PubMed Central

Agarwal, Sumit; Driscoll, John C.; Laibson, David I.

2013-01-01

We derive the first closed-form optimal refinancing rule: Refinance when the current mortgage interest rate falls below the original rate by at least 1ψ[ϕ+W(−exp(−ϕ))]. In this formula W(.) is the Lambert W-function, ψ=2(ρ+λ)σ,ϕ=1+ψ(ρ+λ)κ∕M(1−τ), ρ is the real discount rate, λ is the expected real rate of exogenous mortgage repayment, σ is the standard deviation of the mortgage rate, κ/M is the ratio of the tax-adjusted refinancing cost and the remaining mortgage value, and τ is the marginal tax rate. This expression is derived by solving a tractable class of refinancing problems. Our quantitative results closely match those reported by researchers using numerical methods. PMID:25843977

Discrimination between closed and open forms of lipases using electrophoretic techniques.

PubMed

Miled, N; Riviere, M; Cavalier, J F; Buono, G; Berti, L; Verger, R

2005-03-15

The enhanced catalytic activity of lipases is often associated with structural changes. The three-dimensional (3D) structures showed that the covalently inhibited lipases exist under their open conformations, in contrast to their native closed forms. We studied the inhibition of various lipases--human and dog gastric lipases, human pancreatic lipase, and Humicola lanuginosa lipase--by the octyl-undecyl phosphonate inhibitor, and we measured the subsequent modifications of their respective electrophoretic mobility. Furthermore, the experimental values of the isoelectric points found for the native (closed) and inhibited (open) lipases are in agreement with theoretical calculations based on the electrostatic potential. We concluded that there is a significant difference in the isoelectric points between the closed (native) and open (inhibited) conformations of the four lipases investigated. Thus, analysis of the electrophoretic pattern is proposed as an easy experimental tool to differentiate between a closed and an open form of a given lipase.

Closed-form summations of Dowker's and related trigonometric sums

NASA Astrophysics Data System (ADS)

Cvijović, Djurdje; Srivastava, H. M.

2012-09-01

Through a unified and relatively simple approach which uses complex contour integrals, particularly convenient integration contours and calculus of residues, closed-form summation formulas for 12 very general families of trigonometric sums are deduced. One of them is a family of cosecant sums which was first summed in closed form in a series of papers by Dowker (1987 Phys. Rev. D 36 3095-101 1989 J. Math. Phys. 30 770-3 1992 J. Phys. A: Math. Gen. 25 2641-8), whose method has inspired our work in this area. All of the formulas derived here involve the higher-order Bernoulli polynomials. This article is part of a special issue of Journal of Physics A: Mathematical and Theoretical in honour of Stuart Dowker's 75th birthday devoted to ‘Applications of zeta functions and other spectral functions in mathematics and physics’.

Hamiltonian BFV-BRST theory of closed quantum cosmological models

NASA Astrophysics Data System (ADS)

Kamenshchik, A. Yu.; Lyakhovich, S. L.

1997-02-01

We introduce and study a new discrete basis of gravity constraints by making use of harmonic expansion for closed cosmological models. The full set of constraints is split into area-preserving spatial diffeomorphisms, forming closed subalgebra, and Virasoro-like generators. Operational Hamiltonian BFV-BRST quantization is performed in the framework of perturbative expansion in the dimensionless parameter, which is a positive power of the ratio of Planckian volume to the volume of the Universe. For the (N + 1)-dimensional generalization of stationary closed Bianchi-I cosmology the nilpotency condition for the BRST operator is examined in the first quantum approximation. It turns out that a certain relationship between the dimensionality of the space and the spectrum of matter fields emerges from the requirement of quantum consistency of the model.

Hamiltonian BFV-BRST theory of closed quantum cosmological models

NASA Astrophysics Data System (ADS)

Kamenshchik, A. Yu.; Lyakhovich, S. L.

1997-08-01

We introduce and study a new discrete basis of gravity constraints by making use of the harmonic expansion for closed cosmological models. The full set of constraints is split into area-preserving spatial diffeomorphisms, forming a closed subalgebra, and Virasoro-like generators. The operatorial Hamiltonian BFV-BRST quantization is performed in the framework of a perturbative expansion in the dimensionless parameter which is a positive power of the ratio of the Planck volume to the volume of the Universe. For the (N + 1) - dimensional generalization of a stationary closed Bianchi-I cosmology the nilpotency condition for the BRST operator is examined in the first quantum approximation. It turns out that a relationship between the dimensionality of the space and the spectrum of matter fields emerges from the requirement of quantum consistency of the model.

A closed-form solution for steady-state coupled phloem/xylem flow using the Lambert-W function.

PubMed

Hall, A J; Minchin, P E H

2013-12-01

A closed-form solution for steady-state coupled phloem/xylem flow is presented. This incorporates the basic Münch flow model of phloem transport, the cohesion model of xylem flow, and local variation in the xylem water potential and lateral water flow along the transport pathway. Use of the Lambert-W function allows this solution to be obtained under much more general and realistic conditions than has previously been possible. Variation in phloem resistance (i.e. viscosity) with solute concentration, and deviations from the Van't Hoff expression for osmotic potential are included. It is shown that the model predictions match those of the equilibrium solution of a numerical time-dependent model based upon the same mechanistic assumptions. The effect of xylem flow upon phloem flow can readily be calculated, which has not been possible in any previous analytical model. It is also shown how this new analytical solution can handle multiple sources and sinks within a complex architecture, and can describe competition between sinks. The model provides new insights into Münch flow by explicitly including interactions with xylem flow and water potential in the closed-form solution, and is expected to be useful as a component part of larger numerical models of entire plants. © 2013 John Wiley & Sons Ltd.

A closed-form analytical model for predicting 3D boundary layer displacement thickness for the validation of viscous flow solvers

NASA Astrophysics Data System (ADS)

Kumar, V. R. Sanal; Sankar, Vigneshwaran; Chandrasekaran, Nichith; Saravanan, Vignesh; Natarajan, Vishnu; Padmanabhan, Sathyan; Sukumaran, Ajith; Mani, Sivabalan; Rameshkumar, Tharikaa; Nagaraju Doddi, Hema Sai; Vysaprasad, Krithika; Sharan, Sharad; Murugesh, Pavithra; Shankar, S. Ganesh; Nejaamtheen, Mohammed Niyasdeen; Baskaran, Roshan Vignesh; Rahman Mohamed Rafic, Sulthan Ariff; Harisrinivasan, Ukeshkumar; Srinivasan, Vivek

2018-02-01

A closed-form analytical model is developed for estimating the 3D boundary-layer-displacement thickness of an internal flow system at the Sanal flow choking condition for adiabatic flows obeying the physics of compressible viscous fluids. At this unique condition the boundary-layer blockage induced fluid-throat choking and the adiabatic wall-friction persuaded flow choking occur at a single sonic-fluid-throat location. The beauty and novelty of this model is that without missing the flow physics we could predict the exact boundary-layer blockage of both 2D and 3D cases at the sonic-fluid-throat from the known values of the inlet Mach number, the adiabatic index of the gas and the inlet port diameter of the internal flow system. We found that the 3D blockage factor is 47.33 % lower than the 2D blockage factor with air as the working fluid. We concluded that the exact prediction of the boundary-layer-displacement thickness at the sonic-fluid-throat provides a means to correctly pinpoint the causes of errors of the viscous flow solvers. The methodology presented herein with state-of-the-art will play pivotal roles in future physical and biological sciences for a credible verification, calibration and validation of various viscous flow solvers for high-fidelity 2D/3D numerical simulations of real-world flows. Furthermore, our closed-form analytical model will be useful for the solid and hybrid rocket designers for the grain-port-geometry optimization of new generation single-stage-to-orbit dual-thrust-motors with the highest promising propellant loading density within the given envelope without manifestation of the Sanal flow choking leading to possible shock waves causing catastrophic failures.

Closed-form solutions and scaling laws for Kerr frequency combs

PubMed Central

Renninger, William H.; Rakich, Peter T.

2016-01-01

A single closed-form analytical solution of the driven nonlinear Schrödinger equation is developed, reproducing a large class of the behaviors in Kerr-comb systems, including bright-solitons, dark-solitons, and a large class of periodic wavetrains. From this analytical framework, a Kerr-comb area theorem and a pump-detuning relation are developed, providing new insights into soliton- and wavetrain-based combs along with concrete design guidelines for both. This new area theorem reveals significant deviation from the conventional soliton area theorem, which is crucial to understanding cavity solitons in certain limits. Moreover, these closed-form solutions represent the first step towards an analytical framework for wavetrain formation, and reveal new parameter regimes for enhanced Kerr-comb performance. PMID:27108810

Bayesian Multiscale Modeling of Closed Curves in Point Clouds

PubMed Central

Gu, Kelvin; Pati, Debdeep; Dunson, David B.

2014-01-01

Modeling object boundaries based on image or point cloud data is frequently necessary in medical and scientific applications ranging from detecting tumor contours for targeted radiation therapy, to the classification of organisms based on their structural information. In low-contrast images or sparse and noisy point clouds, there is often insufficient data to recover local segments of the boundary in isolation. Thus, it becomes critical to model the entire boundary in the form of a closed curve. To achieve this, we develop a Bayesian hierarchical model that expresses highly diverse 2D objects in the form of closed curves. The model is based on a novel multiscale deformation process. By relating multiple objects through a hierarchical formulation, we can successfully recover missing boundaries by borrowing structural information from similar objects at the appropriate scale. Furthermore, the model’s latent parameters help interpret the population, indicating dimensions of significant structural variability and also specifying a ‘central curve’ that summarizes the collection. Theoretical properties of our prior are studied in specific cases and efficient Markov chain Monte Carlo methods are developed, evaluated through simulation examples and applied to panorex teeth images for modeling teeth contours and also to a brain tumor contour detection problem. PMID:25544786

Comments on "A Closed-Form Solution to Tensor Voting: Theory and Applications".

PubMed

Maggiori, Emmanuel; Lotito, Pablo; Manterola, Hugo Luis; del Fresno, Mariana

2014-12-01

We comment on a paper that describes a closed-form formulation to Tensor Voting, a technique to perceptually group clouds of points, usually applied to infer features in images. The authors proved an analytic solution to the technique, a highly relevant contribution considering that the original formulation required numerical integration, a time-consuming task. Their work constitutes the first closed-form expression for the Tensor Voting framework. In this work we first observe that the proposed formulation leads to unexpected results which do not satisfy the constraints for a Tensor Voting output, hence they cannot be interpreted. Given that the closed-form expression is said to be an analytic equivalent solution, unexpected outputs should not be encountered unless there are flaws in the proof. We analyzed the underlying math to find which were the causes of these unexpected results. In this commentary we show that their proposal does not in fact provide a proper analytic solution to Tensor Voting and we indicate the flaws in the proof.

Jet-boundary and Plan-form Corrections for Partial-Span Models with Reflection-Plane, End-Plate, or No End-Plate in a Closed Circular Wind Tunnel

NASA Technical Reports Server (NTRS)

Sivells, James C; Deters, Owen J

1946-01-01

A method is presented for determining the jet-boundary and plan-form corrections necessary for application to test data for a partial-span model with a reflection plane, an end plate, or no end plate in a closed circular wind tunnel. Examples are worked out for a partial-span model with each of the three end conditions in the Langley 19-foot pressure tunnel and the corrections are applied to measured values of lift, drag, pitching-moment, rolling-moment, and yawing-moment coefficients.

A Closed Form Solution for an Unorthodox Trigonometric Integral

ERIC Educational Resources Information Center

Wu, Yan

2009-01-01

A closed form solution for the trigonometric integral [integral]sec[superscript 2k+1]xdx, k=0,1,2,..., is presented in this article. The result will fill the gap in another trigonometric integral [integral]sec[superscript 2m+1] x tan[superscript 2n]xdx, which is neglected by most of the calculus textbooks due to its foreseeable unorthodox solution…

Closed-Form Evaluation of Mutual Coupling in a Planar Array of Circular Apertures

NASA Technical Reports Server (NTRS)

Bailey, M. C.

1996-01-01

The integral expression for the mutual admittance between circular apertures in a planar array is evaluated in closed form. Very good accuracy is realized when compared with values that were obtained by numerical integration. Utilization of this closed-form expression, for all element pairs that are separated by more than one element spacing, yields extremely accurate results and significantly reduces the computation time that is required to analyze the performance of a large electronically scanning antenna array.

A Microstructure-Based Constitutive Model for Superplastic Forming

NASA Astrophysics Data System (ADS)

Jafari Nedoushan, Reza; Farzin, Mahmoud; Mashayekhi, Mohammad; Banabic, Dorel

2012-11-01

A constitutive model is proposed for simulations of hot metal forming processes. This model is constructed based on dominant mechanisms that take part in hot forming and includes intergranular deformation, grain boundary sliding, and grain boundary diffusion. A Taylor type polycrystalline model is used to predict intergranular deformation. Previous works on grain boundary sliding and grain boundary diffusion are extended to drive three-dimensional macro stress-strain rate relationships for each mechanism. In these relationships, the effect of grain size is also taken into account. The proposed model is first used to simulate step strain-rate tests and the results are compared with experimental data. It is shown that the model can be used to predict flow stresses for various grain sizes and strain rates. The yield locus is then predicted for multiaxial stress states, and it is observed that it is very close to the von Mises yield criterion. It is also shown that the proposed model can be directly used to simulate hot forming processes. Bulge forming process and gas pressure tray forming are simulated, and the results are compared with experimental data.

Stars Form Surprisingly Close to Milky Way's Black Hole

NASA Astrophysics Data System (ADS)

2005-10-01

The supermassive black hole at the center of the Milky Way has surprisingly helped spawn a new generation of stars, according to observations from NASA's Chandra X-ray Observatory. This novel mode of star formation may solve several mysteries about the supermassive black holes that reside at the centers of nearly all galaxies. "Massive black holes are usually known for violence and destruction," said Sergei Nayakshin of the University of Leicester, United Kingdom, and coauthor of a paper on this research in an upcoming issue of the Monthly Notices of the Royal Astronomical Society. "So it's remarkable that this black hole helped create new stars, not just destroy them." Black holes have earned their fearsome reputation because any material -- including stars -- that falls within the so-called event horizon is never seen again. However, these new results indicate that the immense disks of gas known to orbit many black holes at a "safe" distance from the event horizon can help nurture the formation of new stars. Animation of Stars Forming Around Black Hole Animation of Stars Forming Around Black Hole This conclusion came from new clues that could only be revealed in X-rays. Until the latest Chandra results, astronomers have disagreed about the origin of a mysterious group of massive stars discovered by infrared astronomers to be orbiting less than a light year from the Milky Way's central black hole, a.k.a. Sagittarius A*, or Sgr A*. At such close distances to Sgr A*, the standard model for star formation predicts that gas clouds from which stars form should have been ripped apart by tidal forces from the black hole. Two models to explain this puzzle have been proposed. In the disk model, the gravity of a dense disk of gas around Sgr A* offsets the tidal forces and allows stars to form; in the migration model, the stars formed in a star cluster far away from the black hole and migrated in to form the ring of massive stars. The migration scenario predicts about a

Development and Retrospective Clinical Assessment of a Patient-Specific Closed-Form Integro-Differential Equation Model of Plasma Dilution.

PubMed

Atlas, Glen; Li, John K-J; Amin, Shawn; Hahn, Robert G

2017-01-01

A closed-form integro-differential equation (IDE) model of plasma dilution (PD) has been derived which represents both the intravenous (IV) infusion of crystalloid and the postinfusion period. Specifically, PD is mathematically represented using a combination of constant ratio, differential, and integral components. Furthermore, this model has successfully been applied to preexisting data, from a prior human study, in which crystalloid was infused for a period of 30 minutes at the beginning of thyroid surgery. Using Euler's formula and a Laplace transform solution to the IDE, patients could be divided into two distinct groups based on their response to PD during the infusion period. Explicitly, Group 1 patients had an infusion-based PD response which was modeled using an exponentially decaying hyperbolic sine function, whereas Group 2 patients had an infusion-based PD response which was modeled using an exponentially decaying trigonometric sine function. Both Group 1 and Group 2 patients had postinfusion PD responses which were modeled using the same combination of hyperbolic sine and hyperbolic cosine functions. Statistically significant differences, between Groups 1 and 2, were noted with respect to the area under their PD curves during both the infusion and postinfusion periods. Specifically, Group 2 patients exhibited a response to PD which was most likely consistent with a preoperative hypovolemia. Overall, this IDE model of PD appears to be highly "adaptable" and successfully fits clinically-obtained human data on a patient-specific basis, during both the infusion and postinfusion periods. In addition, patient-specific IDE modeling of PD may be a useful adjunct in perioperative fluid management and in assessing clinical volume kinetics, of crystalloid solutions, in real time.

Development and Retrospective Clinical Assessment of a Patient-Specific Closed-Form Integro-Differential Equation Model of Plasma Dilution

PubMed Central

Atlas, Glen; Li, John K-J; Amin, Shawn; Hahn, Robert G

2017-01-01

A closed-form integro-differential equation (IDE) model of plasma dilution (PD) has been derived which represents both the intravenous (IV) infusion of crystalloid and the postinfusion period. Specifically, PD is mathematically represented using a combination of constant ratio, differential, and integral components. Furthermore, this model has successfully been applied to preexisting data, from a prior human study, in which crystalloid was infused for a period of 30 minutes at the beginning of thyroid surgery. Using Euler’s formula and a Laplace transform solution to the IDE, patients could be divided into two distinct groups based on their response to PD during the infusion period. Explicitly, Group 1 patients had an infusion-based PD response which was modeled using an exponentially decaying hyperbolic sine function, whereas Group 2 patients had an infusion-based PD response which was modeled using an exponentially decaying trigonometric sine function. Both Group 1 and Group 2 patients had postinfusion PD responses which were modeled using the same combination of hyperbolic sine and hyperbolic cosine functions. Statistically significant differences, between Groups 1 and 2, were noted with respect to the area under their PD curves during both the infusion and postinfusion periods. Specifically, Group 2 patients exhibited a response to PD which was most likely consistent with a preoperative hypovolemia. Overall, this IDE model of PD appears to be highly “adaptable” and successfully fits clinically-obtained human data on a patient-specific basis, during both the infusion and postinfusion periods. In addition, patient-specific IDE modeling of PD may be a useful adjunct in perioperative fluid management and in assessing clinical volume kinetics, of crystalloid solutions, in real time. PMID:29123436

a Weighted Closed-Form Solution for Rgb-D Data Registration

NASA Astrophysics Data System (ADS)

Vestena, K. M.; Dos Santos, D. R.; Oilveira, E. M., Jr.; Pavan, N. L.; Khoshelham, K.

2016-06-01

Existing 3D indoor mapping of RGB-D data are prominently point-based and feature-based methods. In most cases iterative closest point (ICP) and its variants are generally used for pairwise registration process. Considering that the ICP algorithm requires an relatively accurate initial transformation and high overlap a weighted closed-form solution for RGB-D data registration is proposed. In this solution, we weighted and normalized the 3D points based on the theoretical random errors and the dual-number quaternions are used to represent the 3D rigid body motion. Basically, dual-number quaternions provide a closed-form solution by minimizing a cost function. The most important advantage of the closed-form solution is that it provides the optimal transformation in one-step, it does not need to calculate good initial estimates and expressively decreases the demand for computer resources in contrast to the iterative method. Basically, first our method exploits RGB information. We employed a scale invariant feature transformation (SIFT) for extracting, detecting, and matching features. It is able to detect and describe local features that are invariant to scaling and rotation. To detect and filter outliers, we used random sample consensus (RANSAC) algorithm, jointly with an statistical dispersion called interquartile range (IQR). After, a new RGB-D loop-closure solution is implemented based on the volumetric information between pair of point clouds and the dispersion of the random errors. The loop-closure consists to recognize when the sensor revisits some region. Finally, a globally consistent map is created to minimize the registration errors via a graph-based optimization. The effectiveness of the proposed method is demonstrated with a Kinect dataset. The experimental results show that the proposed method can properly map the indoor environment with an absolute accuracy around 1.5% of the travel of a trajectory.

A closed-form solution to tensor voting: theory and applications.

PubMed

Wu, Tai-Pang; Yeung, Sai-Kit; Jia, Jiaya; Tang, Chi-Keung; Medioni, Gérard

2012-08-01

We prove a closed-form solution to tensor voting (CFTV): Given a point set in any dimensions, our closed-form solution provides an exact, continuous, and efficient algorithm for computing a structure-aware tensor that simultaneously achieves salient structure detection and outlier attenuation. Using CFTV, we prove the convergence of tensor voting on a Markov random field (MRF), thus termed as MRFTV, where the structure-aware tensor at each input site reaches a stationary state upon convergence in structure propagation. We then embed structure-aware tensor into expectation maximization (EM) for optimizing a single linear structure to achieve efficient and robust parameter estimation. Specifically, our EMTV algorithm optimizes both the tensor and fitting parameters and does not require random sampling consensus typically used in existing robust statistical techniques. We performed quantitative evaluation on its accuracy and robustness, showing that EMTV performs better than the original TV and other state-of-the-art techniques in fundamental matrix estimation for multiview stereo matching. The extensions of CFTV and EMTV for extracting multiple and nonlinear structures are underway.

Escaping or connecting? Characteristics of youth who form close online relationships.

PubMed

Wolak, Janis; Mitchell, Kimberly J; Finkelhor, David

2003-02-01

We used data from a US national sample of Internet users, ages 10-17 (N=1501), to explore the characteristics of youth who had formed close relationships with people they met on the Internet (n=210). Girls who had high levels of conflict with parents or were highly troubled were more likely than other girls to have close online relationships, as were boys who had low levels of communication with parents or were highly troubled, compared to other boys. Age, race and aspects of Internet use were also related. We know little about the nature or quality of the close online relationships, but youth with these sorts of problems may be more vulnerable to online exploitation and to other possible ill effects of online relationships. At the same time, these relationships may have helpful aspects.

A closed form slug test theory for high permeability aquifers.

PubMed

Ostendorf, David W; DeGroot, Don J; Dunaj, Philip J; Jakubowski, Joseph

2005-01-01

We incorporate a linear estimate of casing friction into the analytical slug test theory of Springer and Gelhar (1991) for high permeability aquifers. The modified theory elucidates the influence of inertia and casing friction on consistent, closed form equations for the free surface, pressure, and velocity fluctuations for overdamped and underdamped conditions. A consistent, but small, correction for kinetic energy is included as well. A characteristic velocity linearizes the turbulent casing shear stress so that an analytical solution for attenuated, phase shifted pressure fluctuations fits a single parameter (damping frequency) to transducer data from any depth in the casing. Underdamped slug tests of 0.3, 0.6, and 1 m amplitudes at five transducer depths in a 5.1 cm diameter PVC well 21 m deep in the Plymouth-Carver Aquifer yield a consistent hydraulic conductivity of 1.5 x 10(-3) m/s. The Springer and Gelhar (1991) model underestimates the hydraulic conductivity for these tests by as much as 25% by improperly ascribing smooth turbulent casing friction to the aquifer. The match point normalization of Butler (1998) agrees with our fitted hydraulic conductivity, however, when friction is included in the damping frequency. Zurbuchen et al. (2002) use a numerical model to establish a similar sensitivity of hydraulic conductivity to nonlinear casing friction.

Delay chemical master equation: direct and closed-form solutions

PubMed Central

Leier, Andre; Marquez-Lago, Tatiana T.

2015-01-01

The stochastic simulation algorithm (SSA) describes the time evolution of a discrete nonlinear Markov process. This stochastic process has a probability density function that is the solution of a differential equation, commonly known as the chemical master equation (CME) or forward-Kolmogorov equation. In the same way that the CME gives rise to the SSA, and trajectories of the latter are exact with respect to the former, trajectories obtained from a delay SSA are exact representations of the underlying delay CME (DCME). However, in contrast to the CME, no closed-form solutions have so far been derived for any kind of DCME. In this paper, we describe for the first time direct and closed solutions of the DCME for simple reaction schemes, such as a single-delayed unimolecular reaction as well as chemical reactions for transcription and translation with delayed mRNA maturation. We also discuss the conditions that have to be met such that such solutions can be derived. PMID:26345616

Delay chemical master equation: direct and closed-form solutions.

PubMed

Leier, Andre; Marquez-Lago, Tatiana T

2015-07-08

The stochastic simulation algorithm (SSA) describes the time evolution of a discrete nonlinear Markov process. This stochastic process has a probability density function that is the solution of a differential equation, commonly known as the chemical master equation (CME) or forward-Kolmogorov equation. In the same way that the CME gives rise to the SSA, and trajectories of the latter are exact with respect to the former, trajectories obtained from a delay SSA are exact representations of the underlying delay CME (DCME). However, in contrast to the CME, no closed-form solutions have so far been derived for any kind of DCME. In this paper, we describe for the first time direct and closed solutions of the DCME for simple reaction schemes, such as a single-delayed unimolecular reaction as well as chemical reactions for transcription and translation with delayed mRNA maturation. We also discuss the conditions that have to be met such that such solutions can be derived.

An efficient closed-form solution for acoustic emission source location in three-dimensional structures

DOE Office of Scientific and Technical Information (OSTI.GOV)

Li, Xibing; Dong, Longjun, E-mail: csudlj@163.com; Australian Centre for Geomechanics, The University of Western Australia, Crawley, 6009

This paper presents an efficient closed-form solution (ECS) for acoustic emission(AE) source location in three-dimensional structures using time difference of arrival (TDOA) measurements from N receivers, N ≥ 6. The nonlinear location equations of TDOA are simplified to linear equations. The unique analytical solution of AE sources for unknown velocity system is obtained by solving the linear equations. The proposed ECS method successfully solved the problems of location errors resulting from measured deviations of velocity as well as the existence and multiplicity of solutions induced by calculations of square roots in existed close-form methods.

A simple closed-form solution for assessing concentration uncertainty

NASA Astrophysics Data System (ADS)

de Barros, F. P. J.; Fiori, Aldo; Bellin, Alberto

2011-12-01

We propose closed-form approximate solutions for the moments of a nonreactive tracer that can be used in applications, such as risk analysis. This is in line with the tenet that analytical solutions provide useful information, with minimum cost, during initial site characterization efforts and can serve as a preliminary screening tool when used with prior knowledge. We show that with the help of a few assumptions, the first-order solutions of the concentration moments proposed by Fiori and Dagan (2000) can be further simplified to assume a form similar to well-known deterministic solutions, therefore facilitating their use in applications. A highly anisotropic formation is assumed, and we neglect the transverse components of the two-particle correlation trajectory. The proposed solution compares well with the work of Fiori and Dagan while presenting the same simplicity of use of existing solutions for homogeneous porous media.

A model of oil-generation in a waterlogged and closed system

NASA Astrophysics Data System (ADS)

Zhigao, He

This paper presents a new model on synthetic effects on oil-generation in a waterlogged and closed system. It is suggested based on information about oil in high pressure layers (including gas dissolved in oil), marsh gas and its fermentative solution, fermentation processes and mechanisms, gaseous hydrocarbons of carbonate rocks by acid treatment, oil-field water, recent and ancient sediments, and simulation experiments of artificial marsh gas and biological action. The model differs completely from the theory of oil-generation by thermal degradation of kerogen but stresses the synthetic effects of oil-generation in special waterlogged and closed geological systems, the importance of pressure in oil-forming processes, and direct oil generation by micro-organisms. Oil generated directly by micro-organisms is a particular biochemical reaction. Another feature of this model is that generation, migration and accumulation of petroleum are considered as a whole.

Closed form expressions for ABER and capacity over EGK fading channel in presence of CCI

NASA Astrophysics Data System (ADS)

Singh, S. Pratap; Kumar, Sanjay

2017-03-01

Goal of next generation wireless communication system is to achieve very high data rate. Femto-cell is one of the possibilities to achieve the above target. However, co-channel interference (CCI) is the important concern in femto-cell. This paper presents closed form expressions for average bit error rate (ABER) and capacity for different adaptive schemes under extended generalised-K (EGK) fading channel in the presence of CCI. A novel conditional unified expression (CUE) is derived, which results different conditional error probability and normalised average capacity. Using CUE, a generic expression for ABER is obtained. In addition, closed form expressions for ABER for different modulation schemes under EGK fading channel in presence of CCI are also derived. Further, it is shown that generic ABER expression results into ABER of different modulation schemes. Besides, the closed form expressions of capacity for different adaptive schemes under EGK in presence of CCI are derived. Finally, analytical and simulated results are obtained with excellent agreement.

A General Closed-Form Solution for the Lunar Reconnaissance Orbiter (LRO) Antenna Pointing System

NASA Technical Reports Server (NTRS)

Shah, Neerav; Chen, J. Roger; Hashmall, Joseph A.

2010-01-01

antenna orientation. The nominal geometry for the HGA involves an outer gimbal axis that is exactly perpendicular to the inner gimbal axis, and a target direction that is exactly perpendicular to the outer gimbal axis. For this nominal geometry, closed-form solutions of the desired gimbal angles are simple to get for a desired target direction specified in the spacecraft body fame. If the gimbal axes and the antenna boresight are slightly misaligned, the nominal closed-form solution is not sufficiently accurate for computing the gimbal angles needed to point at a target. In this situation, either a general closed-form solution has to be developed for a mechanism with general geometries, or a correction scheme has to be applied to the nominal closed-form solutions. The latter has been adopted for Solar Dynamics Observatory (SDO) as can be seen in Reference 1, and the former has been used for LRO. The advantage of the general closed-form solution is the use of a small number of parameters for the correction of nominal solutions, especially in the regions near singularities. Singularities here refer to cases when the nominal closed-form solutions have two or more solutions. Algorithm complexity, however, is the disadvantage of the general closed-form solution.

Closed-form recursive formula for an optimal tracker with terminal constraints

NASA Technical Reports Server (NTRS)

Juang, J.-N.; Turner, J. D.; Chun, H. M.

1984-01-01

Feedback control laws are derived for a class of optimal finite time tracking problems with terminal constraints. Analytical solutions are obtained for the feedback gain and the closed-loop response trajectory. Such formulations are expressed in recursive forms so that a real-time computer implementation becomes feasible. Two examples are given to illustrate the validity and usefulness of the formulations.

Cosmic ray antiprotons in closed galaxy model

NASA Technical Reports Server (NTRS)

Protheroe, R.

1981-01-01

The flux of secondary antiprotons expected for the leaky-box model was calculated as well as that for the closed galaxy model of Peters and Westergard (1977). The antiproton/proton ratio observed at several GeV is a factor of 4 higher than the prediction for the leaky-box model but is consistent with that predicted for the closed galaxy model. New low energy data is not consistent with either model. The possibility of a primary antiproton component is discussed.

Closed-form recursive formula for an optimal tracker with terminal constraints

NASA Technical Reports Server (NTRS)

Juang, J. N.; Turner, J. D.; Chun, H. M.

1986-01-01

Feedback control laws are derived for a class of optimal finite time tracking problems with terminal constraints. Analytical solutions are obtained for the feedback gain and the closed-loop response trajectory. Such formulations are expressed in recursive forms so that a real-time computer implementation becomes feasible. An example involving the feedback slewing of a flexible spacecraft is given to illustrate the validity and usefulness of the formulations.

Probing the closed-loop model of mRNA translation in living cells

PubMed Central

Archer, Stuart K; Shirokikh, Nikolay E; Hallwirth, Claus V; Beilharz, Traude H; Preiss, Thomas

2015-01-01

The mRNA closed-loop, formed through interactions between the cap structure, poly(A) tail, eIF4E, eIF4G and PAB, features centrally in models of eukaryotic translation initiation, although direct support for its existence in vivo is not well established. Here, we investigated the closed-loop using a combination of mRNP isolation from rapidly cross-linked cells and high-throughput qPCR. Using the interaction between these factors and the opposing ends of mRNAs as a proxy for the closed-loop, we provide evidence that it is prevalent for eIF4E/4G-bound but unexpectedly sparse for PAB1-bound mRNAs, suggesting it primarily occurs during a distinct phase of polysome assembly. We observed mRNA-specific variation in the extent of closed-loop formation, consistent with a role for polysome topology in the control of gene expression. PMID:25826658

Differential Models for B-Type Open-Closed Topological Landau-Ginzburg Theories

NASA Astrophysics Data System (ADS)

Babalic, Elena Mirela; Doryn, Dmitry; Lazaroiu, Calin Iuliu; Tavakol, Mehdi

2018-05-01

We propose a family of differential models for B-type open-closed topological Landau-Ginzburg theories defined by a pair (X,W), where X is any non-compact Calabi-Yau manifold and W is any holomorphic complex-valued function defined on X whose critical set is compact. The models are constructed at cochain level using smooth data, including the twisted Dolbeault algebra of polyvector-valued forms and a twisted Dolbeault category of holomorphic factorizations of W. We give explicit proposals for cochain level versions of the bulk and boundary traces and for the bulk-boundary and boundary-bulk maps of the Landau-Ginzburg theory. We prove that most of the axioms of an open-closed TFT (topological field theory) are satisfied on cohomology and conjecture that the remaining two axioms (namely non-degeneracy of bulk and boundary traces and the topological Cardy constraint) are also satisfied.

An exact closed form solution for constant area compressible flow with friction and heat transfer

NASA Technical Reports Server (NTRS)

Sturas, J. I.

1971-01-01

The well-known differential equation for the one-dimensional flow of a compressible fluid with heat transfer and wall friction has no known solution in closed form for the general case. This report presents a closed form solution for the special case of constant heat flux per unit length and constant specific heat. The solution was obtained by choosing the square of a dimensionless flow parameter as one of the independent variables to describe the flow. From this exact solution, an approximate simplified form is derived that is applicable for predicting subsonic flow performance characteristics for many types of constant area passages in internal flow. The data included in this report are considered sufficiently accurate for use as a guide in analyzing and designing internal gas flow systems.

Closed-form solutions for a class of optimal quadratic regulator problems with terminal constraints

NASA Technical Reports Server (NTRS)

Juang, J.-N.; Turner, J. D.; Chun, H. M.

1984-01-01

Closed-form solutions are derived for coupled Riccati-like matrix differential equations describing the solution of a class of optimal finite time quadratic regulator problems with terminal constraints. Analytical solutions are obtained for the feedback gains and the closed-loop response trajectory. A computational procedure is presented which introduces new variables for efficient computation of the terminal control law. Two examples are given to illustrate the validity and usefulness of the theory.

SU-F-T-144: Analytical Closed Form Approximation for Carbon Ion Bragg Curves in Water

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tuomanen, S; Moskvin, V; Farr, J

2016-06-15

Purpose: Semi-empirical modeling is a powerful computational method in radiation dosimetry. A set of approximations exist for proton ion depth dose distribution (DDD) in water. However, the modeling is more complicated for carbon ions due to fragmentation. This study addresses this by providing and evaluating a new methodology for DDD modeling of carbon ions in water. Methods: The FLUKA, Monte Carlo (MC) general-purpose transport code was used for simulation of carbon DDDs for energies of 100–400 MeV in water as reference data model benchmarking. Based on Thomas Bortfeld’s closed form equation approximating proton Bragg Curves as a basis, we derivedmore » the critical constants for a beam of Carbon ions by applying models of radiation transport by Lee et. al. and Geiger to our simulated Carbon curves. We hypothesized that including a new exponential (κ) residual distance parameter to Bortfeld’s fluence reduction relation would improve DDD modeling for carbon ions. We are introducing an additional term to be added to Bortfeld’s equation to describe fragmentation tail. This term accounts for the pre-peak dose from nuclear fragments (NF). In the post peak region, the NF transport will be treated as new beams utilizing the Glauber model for interaction cross sections and the Abrasion- Ablation fragmentation model. Results: The carbon beam specific constants in the developed model were determined to be : p= 1.75, β=0.008 cm-1, γ=0.6, α=0.0007 cm MeV, σmono=0.08, and the new exponential parameter κ=0.55. This produced a close match for the plateau part of the curve (max deviation 6.37%). Conclusion: The derived semi-empirical model provides an accurate approximation of the MC simulated clinical carbon DDDs. This is the first direct semi-empirical simulation for the dosimetry of therapeutic carbon ions. The accurate modeling of the NF tail in the carbon DDD will provide key insight into distal edge dose deposition formation.« less

Gating of Connexin Channels by transjunctional-voltage: Conformations and models of open and closed states.

PubMed

Bargiello, Thaddeus A; Oh, Seunghoon; Tang, Qingxiu; Bargiello, Nicholas K; Dowd, Terry L; Kwon, Taekyung

2018-01-01

Voltage is an important physiologic regulator of channels formed by the connexin gene family. Connexins are unique among ion channels in that both plasma membrane inserted hemichannels (undocked hemichannels) and intercellular channels (aggregates of which form gap junctions) have important physiological roles. The hemichannel is the fundamental unit of gap junction voltage-gating. Each hemichannel displays two distinct voltage-gating mechanisms that are primarily sensitive to a voltage gradient formed along the length of the channel pore (the transjunctional voltage) rather than sensitivity to the absolute membrane potential (V m or V i-o ). These transjunctional voltage dependent processes have been termed V j - or fast-gating and loop- or slow-gating. Understanding the mechanism of voltage-gating, defined as the sequence of voltage-driven transitions that connect open and closed states, first and foremost requires atomic resolution models of the end states. Although ion channels formed by connexins were among the first to be characterized structurally by electron microscopy and x-ray diffraction in the early 1980's, subsequent progress has been slow. Much of the current understanding of the structure-function relations of connexin channels is based on two crystal structures of Cx26 gap junction channels. Refinement of crystal structure by all-atom molecular dynamics and incorporation of charge changing protein modifications has resulted in an atomic model of the open state that arguably corresponds to the physiologic open state. Obtaining validated atomic models of voltage-dependent closed states is more challenging, as there are currently no methods to solve protein structure while a stable voltage gradient is applied across the length of an oriented channel. It is widely believed that the best approach to solve the atomic structure of a voltage-gated closed ion channel is to apply different but complementary experimental and computational methods and to use

Stresses in adhesively bonded joints - A closed-form solution

NASA Technical Reports Server (NTRS)

Delale, F.; Erdogan, F.; Aydinoglu, M. N.

1981-01-01

The general plane strain problem of adhesively bonded structures consisting of two different, orthotropic adherends is considered, under the assumption that adherend thicknesses are constant and small in relation to the lateral dimensions of the bonded region, so that they may be treated as plates. The problem is reduced to a system of differential equations for the adhesive stresses which is solved in closed form, with a single lap joint and a stiffened plate under various loading conditions being considered as examples. It is found that the plate theory used in the analysis not only predicts the correct trend for adhesive stresses but gives surprisingly accurate results, the solution being obtained by assuming linear stress-strain relations for the adhesive.

Closed-form solutions for linear regulator-design of mechanical systems including optimal weighting matrix selection

NASA Technical Reports Server (NTRS)

Hanks, Brantley R.; Skelton, Robert E.

1991-01-01

This paper addresses the restriction of Linear Quadratic Regulator (LQR) solutions to the algebraic Riccati Equation to design spaces which can be implemented as passive structural members and/or dampers. A general closed-form solution to the optimal free-decay control problem is presented which is tailored for structural-mechanical systems. The solution includes, as subsets, special cases such as the Rayleigh Dissipation Function and total energy. Weighting matrix selection is a constrained choice among several parameters to obtain desired physical relationships. The closed-form solution is also applicable to active control design for systems where perfect, collocated actuator-sensor pairs exist. Some examples of simple spring mass systems are shown to illustrate key points.

Magnetohydrodynamic viscous flow over a nonlinearly moving surface: Closed-form solutions

NASA Astrophysics Data System (ADS)

Fang, Tiegang

2014-05-01

In this paper, the magnetohydrodynamic (MHD) flow over a nonlinearly (power-law velocity) moving surface is investigated analytically and solutions are presented for a few special conditions. The solutions are obtained in closed forms with hyperbolic functions. The effects of the magnetic, the wall moving, and the mass transpiration parameters are discussed. These solutions are important to show the flow physics as well as to be used as bench mark problems for numerical validation and development of new solution schemes.

Closed-form analytical solutions of high-temperature heat pipe startup and frozen startup limitation

NASA Technical Reports Server (NTRS)

Cao, Y.; Faghri, A.

1992-01-01

Previous numerical and experimental studies indicate that the high-temperature heat pipe startup process is characterized by a moving hot zone with relatively sharp fronts. Based on the above observation, a flat-front model for an approximate analytical solution is proposed. A closed-form solution related to the temperature distribution in the hot zone and the hot zone length as a function of time are obtained. The analytical results agree well with the corresponding experimental data, and provide a quick prediction method for the heat pipe startup performance. Finally, a heat pipe limitation related to the frozen startup process is identified, and an explicit criterion for the high-temperature heat pipe startup is derived. The frozen startup limit identified in this paper provides a fundamental guidance for high-temperature heat pipe design.

Closed-form solution for static pull-in voltage of electrostatically actuated clamped-clamped micro/nano beams under the effect of fringing field and van der Waals force

NASA Astrophysics Data System (ADS)

Bhojawala, V. M.; Vakharia, D. P.

2017-12-01

This investigation provides an accurate prediction of static pull-in voltage for clamped-clamped micro/nano beams based on distributed model. The Euler-Bernoulli beam theory is used adapting geometric non-linearity of beam, internal (residual) stress, van der Waals force, distributed electrostatic force and fringing field effects for deriving governing differential equation. The Galerkin discretisation method is used to make reduced-order model of the governing differential equation. A regime plot is presented in the current work for determining the number of modes required in reduced-order model to obtain completely converged pull-in voltage for micro/nano beams. A closed-form relation is developed based on the relationship obtained from curve fitting of pull-in instability plots and subsequent non-linear regression for the proposed relation. The output of regression analysis provides Chi-square (χ 2) tolerance value equals to 1  ×  10-9, adjusted R-square value equals to 0.999 29 and P-value equals to zero, these statistical parameters indicate the convergence of non-linear fit, accuracy of fitted data and significance of the proposed model respectively. The closed-form equation is validated using available data of experimental and numerical results. The relative maximum error of 4.08% in comparison to several available experimental and numerical data proves the reliability of the proposed closed-form equation.

The soil water characteristic as new class of closed-form parametric expressions for the flow duration curve

NASA Astrophysics Data System (ADS)

Sadegh, M.; Vrugt, J. A.; Gupta, H. V.; Xu, C.

2016-04-01

The flow duration curve is a signature catchment characteristic that depicts graphically the relationship between the exceedance probability of streamflow and its magnitude. This curve is relatively easy to create and interpret, and is used widely for hydrologic analysis, water quality management, and the design of hydroelectric power plants (among others). Several mathematical expressions have been proposed to mimic the FDC. Yet, these efforts have not been particularly successful, in large part because available functions are not flexible enough to portray accurately the functional shape of the FDC for a large range of catchments and contrasting hydrologic behaviors. Here, we extend the work of Vrugt and Sadegh (2013) and introduce several commonly used models of the soil water characteristic as new class of closed-form parametric expressions for the flow duration curve. These soil water retention functions are relatively simple to use, contain between two to three parameters, and mimic closely the empirical FDCs of 430 catchments of the MOPEX data set. We then relate the calibrated parameter values of these models to physical and climatological characteristics of the watershed using multivariate linear regression analysis, and evaluate the regionalization potential of our proposed models against those of the literature. If quality of fit is of main importance then the 3-parameter van Genuchten model is preferred, whereas the 2-parameter lognormal, 3-parameter GEV and generalized Pareto models show greater promise for regionalization.

Mathematical modeling relevant to closed artificial ecosystems

USGS Publications Warehouse

DeAngelis, D.L.

2003-01-01

The mathematical modeling of ecosystems has contributed much to the understanding of the dynamics of such systems. Ecosystems can include not only the natural variety, but also artificial systems designed and controlled by humans. These can range from agricultural systems and activated sludge plants, down to mesocosms, microcosms, and aquaria, which may have practical or research applications. Some purposes may require the design of systems that are completely closed, as far as material cycling is concerned. In all cases, mathematical modeling can help not only to understand the dynamics of the system, but also to design methods of control to keep the system operating in desired ranges. This paper reviews mathematical modeling relevant to the simulation and control of closed or semi-closed artificial ecosystems designed for biological production and recycling in applications in space. Published by Elsevier Science Ltd on behalf of COSPAR.

17 CFR 274.11a-1 - Form N-2, registration statement of closed end management investment companies.

Code of Federal Regulations, 2010 CFR

2010-04-01

... statement of closed end management investment companies. 274.11a-1 Section 274.11a-1 Commodity and... management investment companies. This form shall be used as the registration statement to be filed pursuant to section 8(b) of the Investment Company Act of 1940 by closed end management investment companies...

ORBITAL DISTRIBUTIONS OF CLOSE-IN PLANETS AND DISTANT PLANETS FORMED BY SCATTERING AND DYNAMICAL TIDES

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nagasawa, M.; Ida, S., E-mail: nagasawa.m.ad@m.titech.ac.jp

2011-12-01

We investigated the formation of close-in planets (hot Jupiters) by a combination of mutual scattering, Kozai effect, and tidal circularization, through N-body simulations of three gas giant planets, and compared the results with discovered close-in planets. We found that in about 350 cases out of 1200 runs ({approx}30%), the eccentricity of one of the planets is excited highly enough for tidal circularization by mutual close scatterings followed by secular effects due to outer planets, such as the Kozai mechanism, and the planet becomes a close-in planet through the damping of eccentricity and semimajor axis. The formation probability of close-in planetsmore » by such scattering is not affected significantly by the effect of the general relativity and inclusion of inertial modes in addition to fundamental modes in the tides. Detailed orbital distributions of the formed close-in planets and their counterpart distant planets in our simulations were compared with observational data. We focused on the possibility for close-in planets to retain non-negligible eccentricities ({approx}> 0.1) on timescales of {approx}10{sup 9} yr and have high inclinations, because close-in planets in eccentric or highly inclined orbits have recently been discovered. In our simulations we found that as many as 29% of the close-in planets have retrograde orbits, and the retrograde planets tend to have small eccentricities. On the other hand, eccentric close-in planets tend to have orbits of small inclinations.« less

Testing the Role of p21 Activated Kinases in Schwannoma Formation Using a Novel Genetically Engineered Murine Model that Closely Phenocopies Human NF2 Disease

DTIC Science & Technology

2017-06-01

Kinases in Schwannoma Formation Using a Novel Genetically Engineered Murine Model that Closely Phenocopies Human NF2 Disease The views, opinions and...Role of p21 Activated Kinases in Schwannoma Formation Using a Novel Genetically Engineered Murine Model that Closely Phenocopies Human NF2 Disease Form...NOT RETURN YOUR FORM TO THE ABOVE ADDRESS. The major goal of this research project was to genetically and pharmacologically test the requirement of PAK

Intermediate Fidelity Closed Brayton Cycle Power Conversion Model

NASA Technical Reports Server (NTRS)

Lavelle, Thomas M.; Khandelwal, Suresh; Owen, Albert K.

2006-01-01

This paper describes the implementation of an intermediate fidelity model of a closed Brayton Cycle power conversion system (Closed Cycle System Simulation). The simulation is developed within the Numerical Propulsion Simulation System architecture using component elements from earlier models. Of particular interest, and power, is the ability of this new simulation system to initiate a more detailed analysis of compressor and turbine components automatically and to incorporate the overall results into the general system simulation.

Induced seismicity closed-form traffic light system for actuarial decision-making during deep fluid injections.

PubMed

Mignan, A; Broccardo, M; Wiemer, S; Giardini, D

2017-10-19

The rise in the frequency of anthropogenic earthquakes due to deep fluid injections is posing serious economic, societal, and legal challenges to many geo-energy and waste-disposal projects. Existing tools to assess such problems are still inherently heuristic and mostly based on expert elicitation (so-called clinical judgment). We propose, as a complementary approach, an adaptive traffic light system (ATLS) that is function of a statistical model of induced seismicity. It offers an actuarial judgement of the risk, which is based on a mapping between earthquake magnitude and risk. Using data from six underground reservoir stimulation experiments, mostly from Enhanced Geothermal Systems, we illustrate how such a data-driven adaptive forecasting system could guarantee a risk-based safety target. The proposed model, which includes a linear relationship between seismicity rate and flow rate, as well as a normal diffusion process for post-injection, is first confirmed to be representative of the data. Being integrable, the model yields a closed-form ATLS solution that is both transparent and robust. Although simulations verify that the safety target is consistently ensured when the ATLS is applied, the model from which simulations are generated is validated on a limited dataset, hence still requiring further tests in additional fluid injection environments.

Closed form of the Baker-Campbell-Hausdorff formula for the generators of semisimple complex Lie algebras

NASA Astrophysics Data System (ADS)

Matone, Marco

2016-11-01

Recently it has been introduced an algorithm for the Baker-Campbell-Hausdorff (BCH) formula, which extends the Van-Brunt and Visser recent results, leading to new closed forms of BCH formula. More recently, it has been shown that there are 13 types of such commutator algebras. We show, by providing the explicit solutions, that these include the generators of the semisimple complex Lie algebras. More precisely, for any pair, X, Y of the Cartan-Weyl basis, we find W, linear combination of X, Y, such that exp (X) exp (Y)=exp (W). The derivation of such closed forms follows, in part, by using the above mentioned recent results. The complete derivation is provided by considering the structure of the root system. Furthermore, if X, Y, and Z are three generators of the Cartan-Weyl basis, we find, for a wide class of cases, W, a linear combination of X, Y and Z, such that exp (X) exp (Y) exp (Z)=exp (W). It turns out that the relevant commutator algebras are type 1c-i, type 4 and type 5. A key result concerns an iterative application of the algorithm leading to relevant extensions of the cases admitting closed forms of the BCH formula. Here we provide the main steps of such an iteration that will be developed in a forthcoming paper.

Wave propagation in strain gradient poroelastic medium with microinertia: closed-form and finite element solutions

NASA Astrophysics Data System (ADS)

Rosi, Giuseppe; Scala, Ilaria; Nguyen, Vu-Hieu; Naili, Salah

2017-06-01

This article is about ultrasonic wave propagation in microstructured porous media. The classic Biot's model is enriched using a strain gradient approach to be able to capture high-order effects when the wavelength approaches the characteristic size of the microstructure. In order to reproduce actual transmission/reflection experiments performed on poroelastic samples, and to validate the choice of the model, the computation of the time domain response is necessary, as it allows for a direct comparison with experimental results. For obtaining the time response, we use two strategies: on the one hand we compute the closed form solution by using the Laplace and Fourier transforms techniques; on the other hand we used a finite element method. The results are presented for a transmission/reflection test performed on a poroelastic sample immersed in water. The effects introduced by the strain gradient terms are visible in the time response and in agreement with experimental observations. The results can be exploited in characterization of mechanical properties of poroelastic media by enhancing the reliability of quantitative ultrasound techniques.

Closed-loop Habitation Air Revitalization Model for Regenerative Life Support Systems

NASA Technical Reports Server (NTRS)

Hart, Maxwell M.

1991-01-01

The primary function of any life support system is to keep the crew alive by providing breathable air, potable water, edible food, and for disposal of waste. In a well-balanced or regenerative life support system, the various components are each using what is available and producing what is needed by other components so that there will always be enough chemicals in the form in which they are needed. Humans are not just users, but also one of the participating parts of the system. If a system could continuously recycle the original chemicals, this would make it virtually a Closed-loop Habitation (CH). Some difficulties in trying to create a miniature version of a CH are briefly discussed. In a miniature CH, a minimal structure must be provided and the difference must be made up by artificial parts such as physicochemical systems that perform the conversions that the Earth can achieve naturally. To study the interactions of these parts, a computer model was designed that simulates a miniature CH with emphasis on the air revitalization part. It is called the Closed-loop Habitation Air Revitalization Model (CHARM).

Closed-form nonlinear frequency of flexoelectric nanobeams with surface and nonlocal effects under closed circuit electric field

NASA Astrophysics Data System (ADS)

Barati, Mohammad Reza

2018-02-01

Nonlocal and surface effects on nonlinear vibration characteristics of a flexoelectric nanobeams under magnetic field are examined. Eringen’s nonlocal elasticity as well as surface elasticity theories are employed to describe the size-dependency of the flexoelectric nanobeam. Also, flexoelectricity is an important size-dependent phenomena for piezoelectric structures at nanoscale, related to the strain gradient-electric polarization coupling. After the derivation of governing equation via Hamilton’s principle, Galerkin method is employed to satisfy boundary conditions. Also, analytical procedures are implemented to obtain the closed-form nonlinear frequency of flexoelectric nanobeam. It is showed that magnetic field intensity, flexoelectric parameter, nonlocal parameter, elastic foundation and applied voltage on the top surface of the nanobeam have great influences on nonlinear vibration frequency.

Electrons in a closed galaxy model of cosmic rays

NASA Technical Reports Server (NTRS)

Ramaty, R.; Westergaard, N. J.

1976-01-01

The consistency of positrons and electrons was studied using a propagation model in which the cosmic rays are stopped by nuclear collisions or energy losses before they can escape from the galaxy (the closed-galaxy model). The fact that no inconsistency was found between the predictions and the data implies that the protons which produce the positrons by nuclear reactions could have their origin in a large number of distant sources, as opposed to the heavier nuclei which in this model come from a more limited set of sources. The closed-galaxy model predicts steep electron and positron spectra at high energies. None of these are inconsistent with present measurements; but future measurements of the spectrum of high-energy positrons could provide a definite test for the model. The closed-galaxy model also predicts that the interstellar electron intensity below a few GeV is larger than that implied by other models. The consequence of this result is that electron bremsstrahlung is responsible for about 50% of the galactic gamma-ray emission at photon energies greater than 100 MeV.

Star-forming Filament Models

DOE Office of Scientific and Technical Information (OSTI.GOV)

Myers, Philip C., E-mail: pmyers@cfa.harvard.edu

2017-03-20

New models of star-forming filamentary clouds are presented in order to quantify their properties and to predict their evolution. These 2D axisymmetric models describe filaments that have no core, one low-mass core, and one cluster-forming core. They are based on Plummer-like cylinders and spheroids that are bounded by a constant-density surface of finite extent. In contrast to 1D Plummer-like models, they have specific values of length and mass, they approximate observed column density maps, and their distributions of column density ( N -pdfs) are pole-free. Each model can estimate the star-forming potential of a core-filament system by identifying the zonemore » of gas dense enough to form low-mass stars and by counting the number of enclosed thermal Jeans masses. This analysis suggests that the Musca central filament may be near the start of its star-forming life, with enough dense gas to make its first ∼3 protostars, while the Coronet filament is near the midpoint of its star formation, with enough dense gas to add ∼8 protostars to its ∼20 known stars. In contrast, L43 appears to be near the end of its star-forming life, since it lacks enough dense gas to add any new protostars to the two young stellar objectsalready known.« less

46 CFR 308.534 - Certificate to be attached to closing report, Form MA-313-A.

Code of Federal Regulations, 2010 CFR

2010-10-01

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Code of Federal Regulations, 2012 CFR

2012-10-01

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Code of Federal Regulations, 2011 CFR

2011-10-01

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Code of Federal Regulations, 2013 CFR

2013-10-01

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2014-10-01

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Closed-form solution for Eshelby's elliptic inclusion in antiplane elasticity using complex variable

NASA Astrophysics Data System (ADS)

Chen, Y. Z.

2013-12-01

This paper provides a closed-form solution for the Eshelby's elliptic inclusion in antiplane elasticity. In the formulation, the prescribed eigenstarins are not only for the uniform distribution, but also for the linear form. After using the complex variable and the conformal mapping, the continuation condition for the traction and displacement along the interface in the physical plane can be reduced to a condition along the unit circle. The relevant complex potentials defined in the inclusion and the matrix can be separated from the continuation conditions of the traction and displacement along the interface. The expressions of the real strains and stresses in the inclusion from the assumed eigenstrains are presented. Results for the case of linear distribution of eigenstrain are first obtained in the paper.

Closed-loop model identification of cooperative manipulators holding deformable objects

NASA Astrophysics Data System (ADS)

Alkathiri, A. A.; Akmeliawati, R.; Azlan, N. Z.

2017-11-01

This paper presents system identification to obtain the closed-loop models of a couple of cooperative manipulators in a system, which function to hold deformable objects. The system works using the master-slave principle. In other words, one of the manipulators is position-controlled through encoder feedback, while a force sensor gives feedback to the other force-controlled manipulator. Using the closed-loop input and output data, the closed-loop models, which are useful for model-based control design, are estimated. The criteria for model validation are a 95% fit between the measured and simulated output of the estimated models and residual analysis. The results show that for both position and force control respectively, the fits are 95.73% and 95.88%.

Numerical and Experimental Studies on Crash Characteristics of Closed Form Thin—Walled Steel Sections

NASA Astrophysics Data System (ADS)

Veerasamy, M.; Srinivasan, K.; Prakash, Raghu V.

2010-10-01

The crash behavior of Cold Rolled Mild Steel (CRMS) closed form thin section was studied by conducting compressive tests at loading velocities of 5 mm/min and 1000 mm/min. The numerical simulations were conducted for the same experimental conditions to understand the deformation shape, peak forces and energy absorption capacity of sections at different impact velocities. The simulation results correlated well with the experimental results.

A computational study of the open and closed forms of the N-lobe human serum transferrin apoprotein.

PubMed

Rinaldo, David; Field, Martin J

2003-12-01

Human serum transferrin tightly binds ferric ions in the blood stream but is able to release them in cells by a process involving receptor-mediated endocytosis and decrease in pH. Iron binding and release are accompanied by a large conformation change. In this study, we investigate theoretically the open and closed forms of the N-lobe human serum transferrin apoprotein by performing pKa calculations and molecular dynamics and free-energy simulations. In agreement with the hypothesis based on the x-ray crystal structures, our calculations show that there is a shift in the pKa values of the lysines forming the dilysine trigger when the conformation changes. We argue, however, that simple electrostatic repulsion between the lysines is not sufficient to trigger domain opening and, instead, propose an alternative explanation for the dilysine-trigger effect. Analysis of the molecular dynamics and free-energy results indicate that the open form is more mobile than the closed form and is much more stable at pH 5.3, in large part due to entropic effects. Despite a lower free energy, the dynamics simulation of the open form shows that it is flexible enough to sample conformations that are consistent with iron binding.

Closed-Form 3-D Localization for Single Source in Uniform Circular Array with a Center Sensor

NASA Astrophysics Data System (ADS)

Bae, Eun-Hyon; Lee, Kyun-Kyung

A novel closed-form algorithm is presented for estimating the 3-D location (azimuth angle, elevation angle, and range) of a single source in a uniform circular array (UCA) with a center sensor. Based on the centrosymmetry of the UCA and noncircularity of the source, the proposed algorithm decouples and estimates the 2-D direction of arrival (DOA), i.e. azimuth and elevation angles, and then estimates the range of the source. Notwithstanding a low computational complexity, the proposed algorithm provides an estimation performance close to that of the benchmark estimator 3-D MUSIC.

Hippocampal closed-loop modeling and implications for seizure stimulation design.

PubMed

Sandler, Roman A; Song, Dong; Hampson, Robert E; Deadwyler, Sam A; Berger, Theodore W; Marmarelis, Vasilis Z

2015-10-01

Traditional hippocampal modeling has focused on the series of feedforward synapses known as the trisynaptic pathway. However, feedback connections from CA1 back to the hippocampus through the entorhinal cortex (EC) actually make the hippocampus a closed-loop system. By constructing a functional closed-loop model of the hippocampus, one may learn how both physiological and epileptic oscillations emerge and design efficient neurostimulation patterns to abate such oscillations. Point process input-output models where estimated from recorded rodent hippocampal data to describe the nonlinear dynamical transformation from CA3 → CA1, via the schaffer-collateral synapse, and CA1 → CA3 via the EC. Each Volterra-like subsystem was composed of linear dynamics (principal dynamic modes) followed by static nonlinearities. The two subsystems were then wired together to produce the full closed-loop model of the hippocampus. Closed-loop connectivity was found to be necessary for the emergence of theta resonances as seen in recorded data, thus validating the model. The model was then used to identify frequency parameters for the design of neurostimulation patterns to abate seizures. Deep-brain stimulation (DBS) is a new and promising therapy for intractable seizures. Currently, there is no efficient way to determine optimal frequency parameters for DBS, or even whether periodic or broadband stimuli are optimal. Data-based computational models have the potential to be used as a testbed for designing optimal DBS patterns for individual patients. However, in order for these models to be successful they must incorporate the complex closed-loop structure of the seizure focus. This study serves as a proof-of-concept of using such models to design efficient personalized DBS patterns for epilepsy.

Testing Feedback Models with Nearby Star Forming Regions

NASA Astrophysics Data System (ADS)

Doran, E.; Crowther, P.

2012-12-01

The feedback from massive stars plays a crucial role in the evolution of galaxies. Accurate modelling of this feedback is essential in understanding distant star forming regions. Young nearby, high mass (> 104 M⊙) clusters such as R136 (in the 30 Doradus region) are ideal test beds for population synthesis since they host large numbers of spatially resolved massive stars at a pre-supernovae stage. We present a quantitative comparison of empirical calibrations of radiative and mechanical feedback from individual stars in R136, with instantaneous burst predictions from the popular Starburst99 evolution synthesis code. We find that empirical results exceed predictions by factors of ˜3-9, as a result of limiting simulations to an upper limit of 100 M⊙. 100-300 M⊙ stars should to be incorporated in population synthesis models for high mass clusters to bring predictions into close agreement with empirical results.

Closed-form solutions for linear regulator design of mechanical systems including optimal weighting matrix selection

NASA Technical Reports Server (NTRS)

Hanks, Brantley R.; Skelton, Robert E.

1991-01-01

Vibration in modern structural and mechanical systems can be reduced in amplitude by increasing stiffness, redistributing stiffness and mass, and/or adding damping if design techniques are available to do so. Linear Quadratic Regulator (LQR) theory in modern multivariable control design, attacks the general dissipative elastic system design problem in a global formulation. The optimal design, however, allows electronic connections and phase relations which are not physically practical or possible in passive structural-mechanical devices. The restriction of LQR solutions (to the Algebraic Riccati Equation) to design spaces which can be implemented as passive structural members and/or dampers is addressed. A general closed-form solution to the optimal free-decay control problem is presented which is tailored for structural-mechanical system. The solution includes, as subsets, special cases such as the Rayleigh Dissipation Function and total energy. Weighting matrix selection is a constrained choice among several parameters to obtain desired physical relationships. The closed-form solution is also applicable to active control design for systems where perfect, collocated actuator-sensor pairs exist.

Special-case closed form of the Baker-Campbell-Hausdorff formula

NASA Astrophysics Data System (ADS)

Van-Brunt, Alexander; Visser, Matt

2015-06-01

The Baker-Campbell-Hausdorff formula is a general result for the quantity Z(X,Y)=ln ({{e}X}{{e}Y}), where X and Y are not necessarily commuting. For completely general commutation relations between X and Y, (the free Lie algebra), the general result is somewhat unwieldy. However in specific physics applications the commutator [X,Y], while non-zero, might often be relatively simple, which sometimes leads to explicit closed form results. We consider the special case [X,Y]=uX+vY+cI, and show that in this case the general result reduces to Furthermore we explicitly evaluate the symmetric function f(u,v)=f(v,u), demonstrating that and relate this to previously known results. For instance this result includes, but is considerably more general than, results obtained from either the Heisenberg commutator [P,Q]=-i\\hbar I or the creation-destruction commutator [a,{{a}\\dagger }]=I.

Closed-form Jensen-Renyi divergence for mixture of Gaussians and applications to group-wise shape registration.

PubMed

Wang, Fei; Syeda-Mahmood, Tanveer; Vemuri, Baba C; Beymer, David; Rangarajan, Anand

2009-01-01

In this paper, we propose a generalized group-wise non-rigid registration strategy for multiple unlabeled point-sets of unequal cardinality, with no bias toward any of the given point-sets. To quantify the divergence between the probability distributions--specifically Mixture of Gaussians--estimated from the given point sets, we use a recently developed information-theoretic measure called Jensen-Renyi (JR) divergence. We evaluate a closed-form JR divergence between multiple probabilistic representations for the general case where the mixture models differ in variance and the number of components. We derive the analytic gradient of the divergence measure with respect to the non-rigid registration parameters, and apply it to numerical optimization of the group-wise registration, leading to a computationally efficient and accurate algorithm. We validate our approach on synthetic data, and evaluate it on 3D cardiac shapes.

Simscape Modeling of a Custom Closed-Volume Tank

NASA Technical Reports Server (NTRS)

Fischer, Nathaniel P.

2015-01-01

The library for Mathworks Simscape does not currently contain a model for a closed volume fluid tank where the ullage pressure is variable. In order to model a closed-volume variable ullage pressure tank, it was necessary to consider at least two separate cases: a vertical cylinder, and a sphere. Using library components, it was possible to construct a rough model for the cylindrical tank. It was not possible to construct a model for a spherical tank, using library components, due to the variable area. It was decided that, for these cases, it would be preferable to create a custom library component to represent each case, using the Simscape language. Once completed, the components were added to models, where filling and draining the tanks could be simulated. When the models were performing as expected, it was necessary to generate code from the models and run them in Trick (a real-time simulation program). The data output from Trick was then compared to the output from Simscape and found to be within acceptable limits.

Hippocampal closed-loop modeling and implications for seizure stimulation design

NASA Astrophysics Data System (ADS)

Sandler, Roman A.; Song, Dong; Hampson, Robert E.; Deadwyler, Sam A.; Berger, Theodore W.; Marmarelis, Vasilis Z.

2015-10-01

Objective. Traditional hippocampal modeling has focused on the series of feedforward synapses known as the trisynaptic pathway. However, feedback connections from CA1 back to the hippocampus through the entorhinal cortex (EC) actually make the hippocampus a closed-loop system. By constructing a functional closed-loop model of the hippocampus, one may learn how both physiological and epileptic oscillations emerge and design efficient neurostimulation patterns to abate such oscillations. Approach. Point process input-output models where estimated from recorded rodent hippocampal data to describe the nonlinear dynamical transformation from CA3 → CA1, via the schaffer-collateral synapse, and CA1 → CA3 via the EC. Each Volterra-like subsystem was composed of linear dynamics (principal dynamic modes) followed by static nonlinearities. The two subsystems were then wired together to produce the full closed-loop model of the hippocampus. Main results. Closed-loop connectivity was found to be necessary for the emergence of theta resonances as seen in recorded data, thus validating the model. The model was then used to identify frequency parameters for the design of neurostimulation patterns to abate seizures. Significance. Deep-brain stimulation (DBS) is a new and promising therapy for intractable seizures. Currently, there is no efficient way to determine optimal frequency parameters for DBS, or even whether periodic or broadband stimuli are optimal. Data-based computational models have the potential to be used as a testbed for designing optimal DBS patterns for individual patients. However, in order for these models to be successful they must incorporate the complex closed-loop structure of the seizure focus. This study serves as a proof-of-concept of using such models to design efficient personalized DBS patterns for epilepsy.

Hippocampal Closed-Loop Modeling and Implications for Seizure Stimulation Design

PubMed Central

Sandler, Roman A.; Song, Dong; Hampson, Robert E.; Deadwyler, Sam A.; Berger, Theodore W.; Marmarelis, Vasilis Z.

2016-01-01

Objective Traditional hippocampal modeling has focused on the series of feedforward synapses known as the trisynaptic pathway. However, feedback connections from CA1 back to the hippocampus through the Entorhinal Cortex (EC) actually make the hippocampus a closed-loop system. By constructing a functional closed-loop model of the hippocampus, one may learn how both physiological and epileptic oscillations emerge and design efficient neurostimulation patterns to abate such oscillations. Approach Point process input-output models where estimated from recorded rodent hippocampal data to describe the nonlinear dynamical transformation from CA3→CA1, via the Schaffer-Collateral synapse, and CA1→CA3 via the EC. Each Volterra-like subsystem was composed of linear dynamics (Principal Dynamic Modes) followed by static nonlinearities. The two subsystems were then wired together to produce the full closed-loop model of the hippocampus. Main Results Closed-loop connectivity was found to be necessary for the emergence of theta resonances as seen in recorded data, thus validating the model. The model was then used to identify frequency parameters for the design of neurostimulation patterns to abate seizures. Significance DBS is a new and promising therapy for intractable seizures. Currently, there is no efficient way to determine optimal frequency parameters for DBS, or even whether periodic or broadband stimuli are optimal. Data-based computational models have the potential to be used as a testbed for designing optimal DBS patterns for individual patients. However, in order for these models to be successful they must incorporate the complex closed-loop structure of the seizure focus. This study serves as a proof-of-concept of using such models to design efficient personalized DBS patterns for epilepsy. PMID:26355815

A parallel offline CFD and closed-form approximation strategy for computationally efficient analysis of complex fluid flows

NASA Astrophysics Data System (ADS)

Allphin, Devin

Computational fluid dynamics (CFD) solution approximations for complex fluid flow problems have become a common and powerful engineering analysis technique. These tools, though qualitatively useful, remain limited in practice by their underlying inverse relationship between simulation accuracy and overall computational expense. While a great volume of research has focused on remedying these issues inherent to CFD, one traditionally overlooked area of resource reduction for engineering analysis concerns the basic definition and determination of functional relationships for the studied fluid flow variables. This artificial relationship-building technique, called meta-modeling or surrogate/offline approximation, uses design of experiments (DOE) theory to efficiently approximate non-physical coupling between the variables of interest in a fluid flow analysis problem. By mathematically approximating these variables, DOE methods can effectively reduce the required quantity of CFD simulations, freeing computational resources for other analytical focuses. An idealized interpretation of a fluid flow problem can also be employed to create suitably accurate approximations of fluid flow variables for the purposes of engineering analysis. When used in parallel with a meta-modeling approximation, a closed-form approximation can provide useful feedback concerning proper construction, suitability, or even necessity of an offline approximation tool. It also provides a short-circuit pathway for further reducing the overall computational demands of a fluid flow analysis, again freeing resources for otherwise unsuitable resource expenditures. To validate these inferences, a design optimization problem was presented requiring the inexpensive estimation of aerodynamic forces applied to a valve operating on a simulated piston-cylinder heat engine. The determination of these forces was to be found using parallel surrogate and exact approximation methods, thus evidencing the comparative

Applying Computer Models to Realize Closed-Loop Neonatal Oxygen Therapy.

PubMed

Morozoff, Edmund; Smyth, John A; Saif, Mehrdad

2017-01-01

Within the context of automating neonatal oxygen therapy, this article describes the transformation of an idea verified by a computer model into a device actuated by a computer model. Computer modeling of an entire neonatal oxygen therapy system can facilitate the development of closed-loop control algorithms by providing a verification platform and speeding up algorithm development. In this article, we present a method of mathematically modeling the system's components: the oxygen transport within the patient, the oxygen blender, the controller, and the pulse oximeter. Furthermore, within the constraints of engineering a product, an idealized model of the neonatal oxygen transport component may be integrated effectively into the control algorithm of a device, referred to as the adaptive model. Manual and closed-loop oxygen therapy performance were defined in this article by 3 criteria in the following order of importance: percent duration of SpO2 spent in normoxemia (target SpO2 ± 2.5%), hypoxemia (less than normoxemia), and hyperoxemia (more than normoxemia); number of 60-second periods <85% SpO2 and >95% SpO2; and number of manual adjustments. Results from a clinical evaluation that compared the performance of 3 closed-loop control algorithms (state machine, proportional-integral-differential, and adaptive model) with manual oxygen therapy on 7 low-birth-weight ventilated preterm babies, are presented. Compared with manual therapy, all closed-loop control algorithms significantly increased the patients' duration in normoxemia and reduced hyperoxemia (P < 0.05). The number of manual adjustments was also significantly reduced by all of the closed-loop control algorithms (P < 0.05). Although the performance of the 3 control algorithms was equivalent, it is suggested that the adaptive model, with its ease of use, may have the best utility.

Comment on ‘Special-case closed form of the Baker-Campbell-Hausdorff formula’

NASA Astrophysics Data System (ADS)

Lo, C. F.

2016-05-01

Recently Van-Brunt and Visser (2015 J. Phys. A: Math. Theor. 48 225207) succeeded in explicitly evaluating the Baker-Campbell-Hausdorff (BCH) expansion series for the noncommuting operators X and Y, provided that the two operators satisfy the commutation relation: [X,Y]={uX}+{vY}+{cI}, and the operator I commutes with both of them. In this comment we show that the closed-form BCH formula of this special case can be straightforwardly derived by the means of the Wei-Norman theorem and no summation of the infinite series is needed.

Closed Field Coronal Heating Models Inspired by Wave Turbulence

NASA Astrophysics Data System (ADS)

Downs, C.; Lionello, R.; Mikic, Z.; Linker, J.; Velli, M. M.

2013-12-01

To simulate the energy balance of coronal plasmas on macroscopic scales, we often require the specification of the coronal heating mechanism in some functional form. To go beyond empirical formulations and to build a more physically motivated heating function, we investigate the wave-turbulence dissipation (WTD) phenomenology for the heating of closed coronal loops. To do so, we employ an implementation of non-WKB equations designed to capture the large-scale propagation, reflection, and dissipation of wave turbulence along a loop. The parameter space of this model is explored by solving the coupled WTD and hydrodynamic equations in 1D for an idealized loop, and the relevance to a range of solar conditions is established by computing solutions for several hundred loops extracted from a realistic 3D coronal field. Due to the implicit dependence of the WTD heating model on loop geometry and plasma properties along the loop and at the footpoints, we find that this model can significantly reduce the number of free parameters when compared to traditional empirical heating models, and still robustly describe a broad range of quiet-sun and active region conditions. The importance of the self-reflection term in producing realistic heating scale heights and thermal non-equilibrium cycles is discussed, and preliminary 3D thermodynamic MHD simulations using this formulation are presented. Research supported by NASA and NSF.

46 CFR 308.535 - Certificate to be attached to final closing report, Form MA-313-B.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 8 2014-10-01 2014-10-01 false Certificate to be attached to final closing report, Form MA-313-B. 308.535 Section 308.535 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Cargo Insurance Open Policy War Risk Cargo Insurance § 308...

Closed-Form Jensen-Renyi Divergence for Mixture of Gaussians and Applications to Group-Wise Shape Registration*

PubMed Central

Wang, Fei; Syeda-Mahmood, Tanveer; Vemuri, Baba C.; Beymer, David; Rangarajan, Anand

2010-01-01

In this paper, we propose a generalized group-wise non-rigid registration strategy for multiple unlabeled point-sets of unequal cardinality, with no bias toward any of the given point-sets. To quantify the divergence between the probability distributions – specifically Mixture of Gaussians – estimated from the given point sets, we use a recently developed information-theoretic measure called Jensen-Renyi (JR) divergence. We evaluate a closed-form JR divergence between multiple probabilistic representations for the general case where the mixture models differ in variance and the number of components. We derive the analytic gradient of the divergence measure with respect to the non-rigid registration parameters, and apply it to numerical optimization of the group-wise registration, leading to a computationally efficient and accurate algorithm. We validate our approach on synthetic data, and evaluate it on 3D cardiac shapes. PMID:20426043

The Experiences in Close Relationship Scale (ECR)-short form: reliability, validity, and factor structure.

PubMed

Wei, Meifen; Russell, Daniel W; Mallinckrodt, Brent; Vogel, David L

2007-04-01

We developed a 12-item, short form of the Experiences in Close Relationship Scale (ECR; Brennan, Clark, & Shaver, 1998) across 6 studies. In Study 1, we examined the reliability and factor structure of the measure. In Studies 2 and 3, we cross-validated the reliability, factor structure, and validity of the short form measure; whereas in Study 4, we examined test-retest reliability over a 1-month period. In Studies 5 and 6, we further assessed the reliability, factor structure, and validity of the short version of the ECR when administered as a stand-alone instrument. Confirmatory factor analyses indicated that 2 factors, labeled Anxiety and Avoidance, provided a good fit to the data after removing the influence of response sets. We found validity to be equivalent for the short and the original versions of the ECR across studies. Finally, the results were comparable when we embedded the short form within the original version of the ECR and when we administered it as a stand-alone measure.

Quantitative accuracy of the closed-form least-squares solution for targeted SPECT.

PubMed

Shcherbinin, S; Celler, A

2010-10-07

The aim of this study is to investigate the quantitative accuracy of the closed-form least-squares solution (LSS) for single photon emission computed tomography (SPECT). The main limitation for employing this method in actual clinical reconstructions is the computational cost related to operations with a large-sized system matrix. However, in some clinical situations, the size of the system matrix can be decreased using targeted reconstruction. For example, some oncology SPECT studies are characterized by intense tracer uptakes that are localized in relatively small areas, while the remaining parts of the patient body have only a low activity background. Conventional procedures reconstruct the activity distribution in the whole object, which leads to relatively poor image accuracy/resolution for tumors while computer resources are wasted, trying to rebuild diagnostically useless background. In this study, we apply a concept of targeted reconstruction to SPECT phantom experiments imitating such oncology scans. Our approach includes two major components: (i) disconnection of the entire imaging system of equations and extraction of only those parts that correspond to the targets, i.e., regions of interest (ROI) encompassing active containers/tumors and (ii) generation of the closed-form LSS for each target ROI. We compared these ROI-based LSS with those reconstructed by the conventional MLEM approach. The analysis of the five processed cases from two phantom experiments demonstrated that the LSS approach outperformed MLEM in terms of the noise level inside ROI. On the other hand, MLEM better recovered total activity if the number of iterations was large enough. For the experiment without background activity, the ROI-based LSS led to noticeably better spatial activity distribution inside ROI. However, the distributions pertaining to both approaches were practically identical for the experiment with the concentration ratio 7:1 between the containers and the background.

Closed-form eigensolutions of nonviscously, nonproportionally damped systems based on continuous damping sensitivity

NASA Astrophysics Data System (ADS)

Lázaro, Mario

2018-01-01

In this paper, nonviscous, nonproportional, vibrating structures are considered. Nonviscously damped systems are characterized by dissipative mechanisms which depend on the history of the response velocities via hereditary kernel functions. Solutions of the free motion equation lead to a nonlinear eigenvalue problem involving mass, stiffness and damping matrices. Viscoelasticity leads to a frequency dependence of this latter. In this work, a novel closed-form expression to estimate complex eigenvalues is derived. The key point is to consider the damping model as perturbed by a continuous fictitious parameter. Assuming then the eigensolutions as function of this parameter, the computation of the eigenvalues sensitivity leads to an ordinary differential equation, from whose solution arises the proposed analytical formula. The resulting expression explicitly depends on the viscoelasticity (frequency derivatives of the damping function), the nonproportionality (influence of the modal damping matrix off-diagonal terms). Eigenvectors are obtained using existing methods requiring only the corresponding eigenvalue. The method is validated using a numerical example which compares proposed with exact ones and with those determined from the linear first order approximation in terms of the damping matrix. Frequency response functions are also plotted showing that the proposed approach is valid even for moderately or highly damped systems.

Integration Of Heat Transfer Coefficient In Glass Forming Modeling With Special Interface Element

NASA Astrophysics Data System (ADS)

Moreau, P.; César de Sá, J.; Grégoire, S.; Lochegnies, D.

2007-05-01

Numerical modeling of the glass forming processes requires the accurate knowledge of the heat exchange between the glass and the forming tools. A laboratory testing is developed to determine the evolution of the heat transfer coefficient in different glass/mould contact conditions (contact pressure, temperature, lubrication…). In this paper, trials are performed to determine heat transfer coefficient evolutions in experimental conditions close to the industrial blow-and-blow process conditions. In parallel of this work, a special interface element is implemented in a commercial Finite Element code in order to deal with heat transfer between glass and mould for non-meshing meshes and evolutive contact. This special interface element, implemented by using user subroutines, permits to introduce the previous heat transfer coefficient evolutions in the numerical modelings at the glass/mould interface in function of the local temperatures, contact pressures, contact time and kind of lubrication. The blow-and-blow forming simulation of a perfume bottle is finally performed to assess the special interface element performance.

Effective closed form mathematical approach to determine kinetic constants of NR vulcanized with sulphur and accelerators at different concentrations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Milani, Gabriele, E-mail: milani@stru.polimi.it, E-mail: gabriele.milani@polimi.it; Hanel, Thomas; Donetti, Raffaella

2015-03-10

The basic reaction scheme due to Han and co-workers for NR vulcanized with sulphur is adopted and modified taking into account the single contributions of the different accelerators, focusing in particular on some experimental data ad hoc obtained at Pirelli’s laboratories, where NR was vulcanized at different temperatures (from 150 to 180 °C) and concentrations of sulphur, using TBBS and DPG in the mixture as co-agents. Typically, the chain reactions are initiated by the formation of macro-compounds that are responsible of the formation of the unmatured crosslinked polymer. This first reaction depends on the reciprocal concentrations of all components andmore » their chemical nature. In presence of two accelerators, it was considered that the reactions between each single accelerator and the NR raw material occur in parallel, making the reasonable assumption that there are no mutual reactions between the two accelerators. From the kinetic scheme adopted, a closed form solution was found for the crosslink density, with the only limitation that the induction period is excluded from computations. Even kinetic constants are evaluated in closed form, avoiding a numerically demanding least-squares best fitting on rheometer experimental data. Two series of experiments available, relying into rheometer curves at different temperatures and different concentrations of sulphur and accelerator, are utilized to evaluate the fitting capabilities of the mathematical model. Very good agreement between numerical output and experimental data is experienced in all cases analysed.« less

Closed-form confidence intervals for functions of the normal mean and standard deviation.

PubMed

Donner, Allan; Zou, G Y

2012-08-01

Confidence interval methods for a normal mean and standard deviation are well known and simple to apply. However, the same cannot be said for important functions of these parameters. These functions include the normal distribution percentiles, the Bland-Altman limits of agreement, the coefficient of variation and Cohen's effect size. We present a simple approach to this problem by using variance estimates recovered from confidence limits computed for the mean and standard deviation separately. All resulting confidence intervals have closed forms. Simulation results demonstrate that this approach performs very well for limits of agreement, coefficients of variation and their differences.

CFORM- LINEAR CONTROL SYSTEM DESIGN AND ANALYSIS: CLOSED FORM SOLUTION AND TRANSIENT RESPONSE OF THE LINEAR DIFFERENTIAL EQUATION

NASA Technical Reports Server (NTRS)

Jamison, J. W.

1994-01-01

CFORM was developed by the Kennedy Space Center Robotics Lab to assist in linear control system design and analysis using closed form and transient response mechanisms. The program computes the closed form solution and transient response of a linear (constant coefficient) differential equation. CFORM allows a choice of three input functions: the Unit Step (a unit change in displacement); the Ramp function (step velocity); and the Parabolic function (step acceleration). It is only accurate in cases where the differential equation has distinct roots, and does not handle the case for roots at the origin (s=0). Initial conditions must be zero. Differential equations may be input to CFORM in two forms - polynomial and product of factors. In some linear control analyses, it may be more appropriate to use a related program, Linear Control System Design and Analysis (KSC-11376), which uses root locus and frequency response methods. CFORM was written in VAX FORTRAN for a VAX 11/780 under VAX VMS 4.7. It has a central memory requirement of 30K. CFORM was developed in 1987.

A closed-loop multi-level model of glucose homeostasis

PubMed Central

Uluseker, Cansu; Simoni, Giulia; Dauriz, Marco; Matone, Alice

2018-01-01

Background The pathophysiologic processes underlying the regulation of glucose homeostasis are considerably complex at both cellular and systemic level. A comprehensive and structured specification for the several layers of abstraction of glucose metabolism is often elusive, an issue currently solvable with the hierarchical description provided by multi-level models. In this study we propose a multi-level closed-loop model of whole-body glucose homeostasis, coupled with the molecular specifications of the insulin signaling cascade in adipocytes, under the experimental conditions of normal glucose regulation and type 2 diabetes. Methodology/Principal findings The ordinary differential equations of the model, describing the dynamics of glucose and key regulatory hormones and their reciprocal interactions among gut, liver, muscle and adipose tissue, were designed for being embedded in a modular, hierarchical structure. The closed-loop model structure allowed self-sustained simulations to represent an ideal in silico subject that adjusts its own metabolism to the fasting and feeding states, depending on the hormonal context and invariant to circadian fluctuations. The cellular level of the model provided a seamless dynamic description of the molecular mechanisms downstream the insulin receptor in the adipocytes by accounting for variations in the surrounding metabolic context. Conclusions/Significance The combination of a multi-level and closed-loop modeling approach provided a fair dynamic description of the core determinants of glucose homeostasis at both cellular and systemic scales. This model architecture is intrinsically open to incorporate supplementary layers of specifications describing further individual components influencing glucose metabolism. PMID:29420588

Propagation of sound waves through a linear shear layer: A closed form solution

NASA Technical Reports Server (NTRS)

Scott, J. N.

1978-01-01

Closed form solutions are presented for sound propagation from a line source in or near a shear layer. The analysis was exact for all frequencies and was developed assuming a linear velocity profile in the shear layer. This assumption allowed the solution to be expressed in terms of parabolic cyclinder functions. The solution is presented for a line monopole source first embedded in the uniform flow and then in the shear layer. Solutions are also discussed for certain types of dipole and quadrupole sources. Asymptotic expansions of the exact solutions for small and large values of Strouhal number gave expressions which correspond to solutions previously obtained for these limiting cases.

Communication: From close-packed to topologically close-packed: Formation of Laves phases in moderately polydisperse hard-sphere mixtures

NASA Astrophysics Data System (ADS)

Lindquist, Beth A.; Jadrich, Ryan B.; Truskett, Thomas M.

2018-05-01

Particle size polydispersity can help to inhibit crystallization of the hard-sphere fluid into close-packed structures at high packing fractions and thus is often employed to create model glass-forming systems. Nonetheless, it is known that hard-sphere mixtures with modest polydispersity still have ordered ground states. Here, we demonstrate by computer simulation that hard-sphere mixtures with increased polydispersity fractionate on the basis of particle size and a bimodal subpopulation favors the formation of topologically close-packed C14 and C15 Laves phases in coexistence with a disordered phase. The generality of this result is supported by simulations of hard-sphere mixtures with particle-size distributions of four different forms.

Kinematics and dynamics of robotic systems with multiple closed loops

NASA Astrophysics Data System (ADS)

Zhang, Chang-De

The kinematics and dynamics of robotic systems with multiple closed loops, such as Stewart platforms, walking machines, and hybrid manipulators, are studied. In the study of kinematics, focus is on the closed-form solutions of the forward position analysis of different parallel systems. A closed-form solution means that the solution is expressed as a polynomial in one variable. If the order of the polynomial is less than or equal to four, the solution has analytical closed-form. First, the conditions of obtaining analytical closed-form solutions are studied. For a Stewart platform, the condition is found to be that one rotational degree of freedom of the output link is decoupled from the other five. Based on this condition, a class of Stewart platforms which has analytical closed-form solution is formulated. Conditions of analytical closed-form solution for other parallel systems are also studied. Closed-form solutions of forward kinematics for walking machines and multi-fingered grippers are then studied. For a parallel system with three three-degree-of-freedom subchains, there are 84 possible ways to select six independent joints among nine joints. These 84 ways can be classified into three categories: Category 3:3:0, Category 3:2:1, and Category 2:2:2. It is shown that the first category has no solutions; the solutions of the second category have analytical closed-form; and the solutions of the last category are higher order polynomials. The study is then extended to a nearly general Stewart platform. The solution is a 20th order polynomial and the Stewart platform has a maximum of 40 possible configurations. Also, the study is extended to a new class of hybrid manipulators which consists of two serially connected parallel mechanisms. In the study of dynamics, a computationally efficient method for inverse dynamics of manipulators based on the virtual work principle is developed. Although this method is comparable with the recursive Newton-Euler method for

Stresses in adhesively bonded joints: A closed form solution. [plate theory

NASA Technical Reports Server (NTRS)

Delale, F.; Erdogan, F.; Aydinoglu, M. N.

1980-01-01

The plane strain of adhesively bonded structures which consist of two different orthotropic adherents is considered. Assuming that the thicknesses of the adherends are constant and are small in relation to the lateral dimensions of the bonded region, the adherends are treated as plates. The transverse shear effects in the adherends and the in-plane normal strain in the adhesive are taken into account. The problem is reduced to a system of differential equations for the adhesive stresses which is solved in closed form. A single lap joint and a stiffened plate under various loading conditions are considered as examples. To verify the basic trend of the solutions obtained from the plate theory a sample problem is solved by using the finite element method and by treating the adherends and the adhesive as elastic continua. The plate theory not only predicts the correct trend for the adhesive stresses but also gives rather surprisingly accurate results.

Integration Of Heat Transfer Coefficient In Glass Forming Modeling With Special Interface Element

DOE Office of Scientific and Technical Information (OSTI.GOV)

Moreau, P.; Gregoire, S.; Lochegnies, D.

2007-05-17

Numerical modeling of the glass forming processes requires the accurate knowledge of the heat exchange between the glass and the forming tools. A laboratory testing is developed to determine the evolution of the heat transfer coefficient in different glass/mould contact conditions (contact pressure, temperature, lubrication...). In this paper, trials are performed to determine heat transfer coefficient evolutions in experimental conditions close to the industrial blow-and-blow process conditions. In parallel of this work, a special interface element is implemented in a commercial Finite Element code in order to deal with heat transfer between glass and mould for non-meshing meshes and evolutivemore » contact. This special interface element, implemented by using user subroutines, permits to introduce the previous heat transfer coefficient evolutions in the numerical modelings at the glass/mould interface in function of the local temperatures, contact pressures, contact time and kind of lubrication. The blow-and-blow forming simulation of a perfume bottle is finally performed to assess the special interface element performance.« less

Forming three-dimensional closed shapes from two-dimensional soft ribbons by controlled buckling

NASA Astrophysics Data System (ADS)

Aoki, Michio; Juang, Jia-Yang

2018-02-01

Conventional manufacturing techniques-moulding, machining and casting-exist to produce three-dimensional (3D) shapes. However, these industrial processes are typically geared for mass production and are not directly applicable to residential settings, where inexpensive and versatile tools are desirable. Moreover, those techniques are, in general, not adequate to process soft elastic materials. Here, we introduce a new concept of forming 3D closed hollow shapes from two-dimensional (2D) elastic ribbons by controlled buckling. We numerically and experimentally characterize how the profile and thickness of the ribbon determine its buckled shape. We find a 2D master profile with which various elliptical 3D shapes can be formed. More complex natural and artificial hollow shapes, such as strawberry, hourglass and wheel, can also be achieved via strategic design and pattern engraving on the ribbons. The nonlinear response of the post-buckling regime is rationalized through finite-element analysis, which shows good quantitative agreement with experiments. This robust fabrication should complement conventional techniques and provide a rich arena for future studies on the mechanics and new applications of elastic hollow structures.

Closed-form Capacity Expressions for the α-μ Fading Channel with SC Diversity under Different Adaptive Transmission Strategies

NASA Astrophysics Data System (ADS)

Mohamed, Refaat; Ismail, Mahmoud H.; Newagy, Fatma; Mourad, Heba M.

2013-03-01

Stemming from the fact that the α-μ fading distribution is one of the very general fading models used in the literature to describe the small scale fading phenomenon, in this paper, closed-form expressions for the Shannon capacity of the α-μ fading channel operating under four main adaptive transmission strategies are derived assuming integer values for μ. These expressions are derived for the case of no diversity as well as for selection combining diversity with independent and identically distributed branches. The obtained expressions reduce to those previously derived in the literature for the Weibull as well as the Rayleigh fading cases, which are both special cases of the α-μ channel. Numerical results are presented for the capacity under the four adaptive transmission strategies and the effect of the fading parameter as well as the number of diversity branches is studied.

Model-Driven Safety Analysis of Closed-Loop Medical Systems

PubMed Central

Pajic, Miroslav; Mangharam, Rahul; Sokolsky, Oleg; Arney, David; Goldman, Julian; Lee, Insup

2013-01-01

In modern hospitals, patients are treated using a wide array of medical devices that are increasingly interacting with each other over the network, thus offering a perfect example of a cyber-physical system. We study the safety of a medical device system for the physiologic closed-loop control of drug infusion. The main contribution of the paper is the verification approach for the safety properties of closed-loop medical device systems. We demonstrate, using a case study, that the approach can be applied to a system of clinical importance. Our method combines simulation-based analysis of a detailed model of the system that contains continuous patient dynamics with model checking of a more abstract timed automata model. We show that the relationship between the two models preserves the crucial aspect of the timing behavior that ensures the conservativeness of the safety analysis. We also describe system design that can provide open-loop safety under network failure. PMID:24177176

Model-Driven Safety Analysis of Closed-Loop Medical Systems.

PubMed

Pajic, Miroslav; Mangharam, Rahul; Sokolsky, Oleg; Arney, David; Goldman, Julian; Lee, Insup

2012-10-26

In modern hospitals, patients are treated using a wide array of medical devices that are increasingly interacting with each other over the network, thus offering a perfect example of a cyber-physical system. We study the safety of a medical device system for the physiologic closed-loop control of drug infusion. The main contribution of the paper is the verification approach for the safety properties of closed-loop medical device systems. We demonstrate, using a case study, that the approach can be applied to a system of clinical importance. Our method combines simulation-based analysis of a detailed model of the system that contains continuous patient dynamics with model checking of a more abstract timed automata model. We show that the relationship between the two models preserves the crucial aspect of the timing behavior that ensures the conservativeness of the safety analysis. We also describe system design that can provide open-loop safety under network failure.

Generalized closed form solutions for feasible dimension limit and pull-in characteristics of nanocantilever under the Influences of van der Waals and Casimir forces

NASA Astrophysics Data System (ADS)

Mukherjee, Banibrata; Sen, Siddhartha

2018-04-01

This paper presents generalized closed form expressions for determining the dimension limit for the basic design parameters as well as the pull-in characteristics of a nanocantilever beam under the influences of van der Waals and Casimir forces. The coupled nonlinear electromechanical problem of electrostatic nanocantilever is formulated in nondimensional form with Galerkin’s approximation considering the effects of these intermolecular forces and fringe field. The resulting integrals and higher order polynomials are solved numerically to derive the closed form expressions for maximum permissible detachment length, minimum feasible gap spacing and critical pull-in limit. The derived expressions are compared and validated as well with several reported literature showing reasonable agreement. The major advantages of the proposed closed form expressions are that, they do not contain any complex mathematical term or operation unlike in reported literature and thus they will serve as convenient tools for the NEMS community in successful design of various electrostatically actuated nanosystems.

Efficient dynamic modeling of manipulators containing closed kinematic loops

NASA Astrophysics Data System (ADS)

Ferretti, Gianni; Rocco, Paolo

An approach to efficiently solve the forward dynamics problem for manipulators containing closed chains is proposed. The two main distinctive features of this approach are: the dynamics of the equivalent open loop tree structures (any closed loop can be in general modeled by imposing some additional kinematic constraints to a suitable tree structure) is computed through an efficient Newton Euler formulation; the constraint equations relative to the most commonly adopted closed chains in industrial manipulators are explicitly solved, thus, overcoming the redundancy of Lagrange's multipliers method while avoiding the inefficiency due to a numerical solution of the implicit constraint equations. The constraint equations considered for an explicit solution are those imposed by articulated gear mechanisms and planar closed chains (pantograph type structures). Articulated gear mechanisms are actually used in all industrial robots to transmit motion from actuators to links, while planar closed chains are usefully employed to increase the stiffness of the manipulators and their load capacity, as well to reduce the kinematic coupling of joint axes. The accuracy and the efficiency of the proposed approach are shown through a simulation test.

Iterative LQG Controller Design Through Closed-Loop Identification

NASA Technical Reports Server (NTRS)

Hsiao, Min-Hung; Huang, Jen-Kuang; Cox, David E.

1996-01-01

This paper presents an iterative Linear Quadratic Gaussian (LQG) controller design approach for a linear stochastic system with an uncertain open-loop model and unknown noise statistics. This approach consists of closed-loop identification and controller redesign cycles. In each cycle, the closed-loop identification method is used to identify an open-loop model and a steady-state Kalman filter gain from closed-loop input/output test data obtained by using a feedback LQG controller designed from the previous cycle. Then the identified open-loop model is used to redesign the state feedback. The state feedback and the identified Kalman filter gain are used to form an updated LQC controller for the next cycle. This iterative process continues until the updated controller converges. The proposed controller design is demonstrated by numerical simulations and experiments on a highly unstable large-gap magnetic suspension system.

Closed loop models for analyzing engineering requirements for simulators

NASA Technical Reports Server (NTRS)

Baron, S.; Muralidharan, R.; Kleinman, D.

1980-01-01

A closed loop analytic model, incorporating a model for the human pilot, (namely, the optimal control model) that would allow certain simulation design tradeoffs to be evaluated quantitatively was developed. This model was applied to a realistic flight control problem. The resulting model is used to analyze both overall simulation effects and the effects of individual elements. The results show that, as compared to an ideal continuous simulation, the discrete simulation can result in significant performance and/or workload penalties.

A Soil Temperature Model for Closed Canopied Forest Stands

Treesearch

James M. Vose; Wayne T. Swank

1991-01-01

A microcomputer-based soil temperature model was developed to predict temperature at the litter-soil interface and soil temperatures at three depths (0.10 m, 0.20 m, and 1.25 m) under closed forest canopies. Comparisons of predicted and measured soil temperatures indicated good model performance under most conditions. When generalized parameters describing soil...

Four Closely Related HIV-1 CRF01_AE/CRF07_BC Recombinant Forms Identified in East China.

PubMed

Li, Fan; Li, Yuxueyun; Feng, Yi; Hu, Jing; Ruan, Yuhua; Xing, Hui; Shao, Yiming

2017-07-01

Five near full-length genomes of novel second-generation HIV-1 recombinant virus (JS150021, JS150029, JS150129, JS150132, and AH150183) were identified from five HIV-positive people in Jiangsu and Anhui province, east China. Phylogenic analyses showed that these five sequences are all composed of two well-established circulating recombinant forms (CRFs) CRF07_BC and CRF01_AE, grouped into four new discovered recombinant forms, which show several very similar but not identical recombinant breakpoints. The four recombinant forms are also identified to be a sort of family or related viruses, seems to be the results of different recombination events. The emergence of a serious new closely related CRF07_BC/CRF01_AE recombinant strain indicates the increasing complexity of sexual transmission of the HIV-1 epidemic in China.

A new approach towards image based virtual 3D city modeling by using close range photogrammetry

NASA Astrophysics Data System (ADS)

Singh, S. P.; Jain, K.; Mandla, V. R.

2014-05-01

3D city model is a digital representation of the Earth's surface and it's related objects such as building, tree, vegetation, and some manmade feature belonging to urban area. The demand of 3D city modeling is increasing day to day for various engineering and non-engineering applications. Generally three main image based approaches are using for virtual 3D city models generation. In first approach, researchers used Sketch based modeling, second method is Procedural grammar based modeling and third approach is Close range photogrammetry based modeling. Literature study shows that till date, there is no complete solution available to create complete 3D city model by using images. These image based methods also have limitations This paper gives a new approach towards image based virtual 3D city modeling by using close range photogrammetry. This approach is divided into three sections. First, data acquisition process, second is 3D data processing, and third is data combination process. In data acquisition process, a multi-camera setup developed and used for video recording of an area. Image frames created from video data. Minimum required and suitable video image frame selected for 3D processing. In second section, based on close range photogrammetric principles and computer vision techniques, 3D model of area created. In third section, this 3D model exported to adding and merging of other pieces of large area. Scaling and alignment of 3D model was done. After applying the texturing and rendering on this model, a final photo-realistic textured 3D model created. This 3D model transferred into walk-through model or in movie form. Most of the processing steps are automatic. So this method is cost effective and less laborious. Accuracy of this model is good. For this research work, study area is the campus of department of civil engineering, Indian Institute of Technology, Roorkee. This campus acts as a prototype for city. Aerial photography is restricted in many country

Forming three-dimensional closed shapes from two-dimensional soft ribbons by controlled buckling

PubMed Central

Aoki, Michio

2018-01-01

Conventional manufacturing techniques—moulding, machining and casting—exist to produce three-dimensional (3D) shapes. However, these industrial processes are typically geared for mass production and are not directly applicable to residential settings, where inexpensive and versatile tools are desirable. Moreover, those techniques are, in general, not adequate to process soft elastic materials. Here, we introduce a new concept of forming 3D closed hollow shapes from two-dimensional (2D) elastic ribbons by controlled buckling. We numerically and experimentally characterize how the profile and thickness of the ribbon determine its buckled shape. We find a 2D master profile with which various elliptical 3D shapes can be formed. More complex natural and artificial hollow shapes, such as strawberry, hourglass and wheel, can also be achieved via strategic design and pattern engraving on the ribbons. The nonlinear response of the post-buckling regime is rationalized through finite-element analysis, which shows good quantitative agreement with experiments. This robust fabrication should complement conventional techniques and provide a rich arena for future studies on the mechanics and new applications of elastic hollow structures. PMID:29515894

Closed-form Static Analysis with Inertia Relief and Displacement-Dependent Loads Using a MSC/NASTRAN DMAP Alter

NASA Technical Reports Server (NTRS)

Barnett, Alan R.; Widrick, Timothy W.; Ludwiczak, Damian R.

1995-01-01

Solving for the displacements of free-free coupled systems acted upon by static loads is commonly performed throughout the aerospace industry. Many times, these problems are solved using static analysis with inertia relief. This solution technique allows for a free-free static analysis by balancing the applied loads with inertia loads generated by the applied loads. For some engineering applications, the displacements of the free-free coupled system induce additional static loads. Hence, the applied loads are equal to the original loads plus displacement-dependent loads. Solving for the final displacements of such systems is commonly performed using iterative solution techniques. Unfortunately, these techniques can be time-consuming and labor-intensive. Since the coupled system equations for free-free systems with displacement-dependent loads can be written in closed-form, it is advantageous to solve for the displacements in this manner. Implementing closed-form equations in static analysis with inertia relief is analogous to implementing transfer functions in dynamic analysis. Using a MSC/NASTRAN DMAP Alter, displacement-dependent loads have been included in static analysis with inertia relief. Such an Alter has been used successfully to solve efficiently a common aerospace problem typically solved using an iterative technique.

Rings from Close Encounters

NASA Astrophysics Data System (ADS)

Kohler, Susanna

2016-09-01

Weve recently discovered narrow sets of rings around two minor planets orbiting in our solar system. How did these rings form? A new study shows that they could be a result of close encounters between the minor planets and giants like Jupiter or Neptune.Unexpected Ring SystemsPositions of the centaurs in our solar system (green). Giant planets (red), Jupiter trojans (grey), scattered disk objects (tan) and Kuiper belt objects (blue) are also shown. [WilyD]Centaurs are minor planets in our solar system that orbit between Jupiter and Neptune. These bodies of which there are roughly 44,000 with diameters larger than 1 km have dynamically unstable orbits that cross paths with those of one or more giant planets.Recent occultation observations of two centaurs, 10199 Chariklo and 2060 Chiron, revealed that these bodies both host narrow ring systems. Besides our four giant planets, Chariklo and Chiron are the only other bodies in the solar system known to have rings. But how did these rings form?Scientists have proposed several models, implicating collisions, disruption of a primordial satellite, or dusty outgassing. But a team of scientists led by Ryuki Hyodo (Paris Institute of Earth Physics, Kobe University) has recently proposed an alternative scenario: what if the rings were formed from partial disruption of the centaur itself, after it crossed just a little too close to a giant planet?Tidal Forces from a GiantHyodo and collaborators first used past studies of centaur orbits to estimate that roughly 10% of centaurs experience close encounters (passing within a distance of ~2x the planetary radius) with a giant planet during their million-year lifetime. The team then performed a series of simulations of close encounters between a giant planet and a differentiated centaur a body in which the rocky material has sunk to form a dense silicate core, surrounded by an icy mantle.Some snapshots of simulation outcomes (click for a closer look!) for different initial states of

Fisheries Closed Areas Strengthen Scallop Larval Settlement and Connectivity Among Closed Areas and Across International Open Fishing Grounds: A Model Study.

PubMed

Davies, Kimberley T A; Gentleman, W C; DiBacco, C; Johnson, C L

2015-09-01

This study examined whether a measured increase in average body size of adult sea scallops inside three fishery closed areas on Georges Bank (GB), United States (US), was sufficient to increase larval supply to closed areas and open fishing areas in both US and Canadian areas of the Bank. The effects of adult scallop density-at-size and fecundity-at-size on egg production were compared among open and closed fishery areas, countries, and time periods before and after the closed areas were established. Estimated egg production was then used to define spawning conditions in a coupled biological-physical larval tracking model that simulated larval development, mortality, and dispersal. Results showed that order of magnitude increases in larval settlement after closure were facilitated by increases in size-dependant egg production inside and dispersal from Closed Areas I and II, but not Nantucket Lightship Closed Area. The distributions of both egg production and larval settlement became more uniform across the Bank, causing the relative contribution of Canadian larvae to US scallop aggregations to decrease after establishment of Closed Areas I and II. Decreases in small and medium-sized scallop density in Canada and decreases in large scallops over the US-Southern Flank after closure caused local declines in egg production but were not sufficient to negatively affect larval settlement at the regional scale. Our model suggests that the establishment of fishery closed areas on GB considerably strengthened larval supply and settlement within and among several adult scallop aggregations.

Fisheries Closed Areas Strengthen Scallop Larval Settlement and Connectivity Among Closed Areas and Across International Open Fishing Grounds: A Model Study

NASA Astrophysics Data System (ADS)

Davies, Kimberley T. A.; Gentleman, W. C.; DiBacco, C.; Johnson, C. L.

2015-09-01

This study examined whether a measured increase in average body size of adult sea scallops inside three fishery closed areas on Georges Bank (GB), United States (US), was sufficient to increase larval supply to closed areas and open fishing areas in both US and Canadian areas of the Bank. The effects of adult scallop density-at-size and fecundity-at-size on egg production were compared among open and closed fishery areas, countries, and time periods before and after the closed areas were established. Estimated egg production was then used to define spawning conditions in a coupled biological-physical larval tracking model that simulated larval development, mortality, and dispersal. Results showed that order of magnitude increases in larval settlement after closure were facilitated by increases in size-dependant egg production inside and dispersal from Closed Areas I and II, but not Nantucket Lightship Closed Area. The distributions of both egg production and larval settlement became more uniform across the Bank, causing the relative contribution of Canadian larvae to US scallop aggregations to decrease after establishment of Closed Areas I and II. Decreases in small and medium-sized scallop density in Canada and decreases in large scallops over the US-Southern Flank after closure caused local declines in egg production but were not sufficient to negatively affect larval settlement at the regional scale. Our model suggests that the establishment of fishery closed areas on GB considerably strengthened larval supply and settlement within and among several adult scallop aggregations.

Closed-loop control of epileptiform activities in a neural population model using a proportional-derivative controller

NASA Astrophysics Data System (ADS)

Wang, Jun-Song; Wang, Mei-Li; Li, Xiao-Li; Ernst, Niebur

2015-03-01

Epilepsy is believed to be caused by a lack of balance between excitation and inhibitation in the brain. A promising strategy for the control of the disease is closed-loop brain stimulation. How to determine the stimulation control parameters for effective and safe treatment protocols remains, however, an unsolved question. To constrain the complex dynamics of the biological brain, we use a neural population model (NPM). We propose that a proportional-derivative (PD) type closed-loop control can successfully suppress epileptiform activities. First, we determine the stability of root loci, which reveals that the dynamical mechanism underlying epilepsy in the NPM is the loss of homeostatic control caused by the lack of balance between excitation and inhibition. Then, we design a PD type closed-loop controller to stabilize the unstable NPM such that the homeostatic equilibriums are maintained; we show that epileptiform activities are successfully suppressed. A graphical approach is employed to determine the stabilizing region of the PD controller in the parameter space, providing a theoretical guideline for the selection of the PD control parameters. Furthermore, we establish the relationship between the control parameters and the model parameters in the form of stabilizing regions to help understand the mechanism of suppressing epileptiform activities in the NPM. Simulations show that the PD-type closed-loop control strategy can effectively suppress epileptiform activities in the NPM. Project supported by the National Natural Science Foundation of China (Grant Nos. 61473208, 61025019, and 91132722), ONR MURI N000141010278, and NIH grant R01EY016281.

Modeling and forecasting foreign exchange daily closing prices with normal inverse Gaussian

NASA Astrophysics Data System (ADS)

Teneng, Dean

2013-09-01

We fit the normal inverse Gaussian(NIG) distribution to foreign exchange closing prices using the open software package R and select best models by Käärik and Umbleja (2011) proposed strategy. We observe that daily closing prices (12/04/2008 - 07/08/2012) of CHF/JPY, AUD/JPY, GBP/JPY, NZD/USD, QAR/CHF, QAR/EUR, SAR/CHF, SAR/EUR, TND/CHF and TND/EUR are excellent fits while EGP/EUR and EUR/GBP are good fits with a Kolmogorov-Smirnov test p-value of 0.062 and 0.08 respectively. It was impossible to estimate normal inverse Gaussian parameters (by maximum likelihood; computational problem) for JPY/CHF but CHF/JPY was an excellent fit. Thus, while the stochastic properties of an exchange rate can be completely modeled with a probability distribution in one direction, it may be impossible the other way around. We also demonstrate that foreign exchange closing prices can be forecasted with the normal inverse Gaussian (NIG) Lévy process, both in cases where the daily closing prices can and cannot be modeled by NIG distribution.

Porous Media Approach for Modeling Closed Cell Foam

NASA Technical Reports Server (NTRS)

Ghosn, Louis J.; Sullivan, Roy M.

2006-01-01

In order to minimize boil off of the liquid oxygen and liquid hydrogen and to prevent the formation of ice on its exterior surface, the Space Shuttle External Tank (ET) is insulated using various low-density, closed-cell polymeric foams. Improved analysis methods for these foam materials are needed to predict the foam structural response and to help identify the foam fracture behavior in order to help minimize foam shedding occurrences. This presentation describes a continuum based approach to modeling the foam thermo-mechanical behavior that accounts for the cellular nature of the material and explicitly addresses the effect of the internal cell gas pressure. A porous media approach is implemented in a finite element frame work to model the mechanical behavior of the closed cell foam. The ABAQUS general purpose finite element program is used to simulate the continuum behavior of the foam. The soil mechanics element is implemented to account for the cell internal pressure and its effect on the stress and strain fields. The pressure variation inside the closed cells is calculated using the ideal gas laws. The soil mechanics element is compatible with an orthotropic materials model to capture the different behavior between the rise and in-plane directions of the foam. The porous media approach is applied to model the foam thermal strain and calculate the foam effective coefficient of thermal expansion. The calculated foam coefficients of thermal expansion were able to simulate the measured thermal strain during heat up from cryogenic temperature to room temperature in vacuum. The porous media approach was applied to an insulated substrate with one inch foam and compared to a simple elastic solution without pore pressure. The porous media approach is also applied to model the foam mechanical behavior during subscale laboratory experiments. In this test, a foam layer sprayed on a metal substrate is subjected to a temperature variation while the metal substrate is

Closed Form Equations for the Preliminary Design of a Heat-Pipe-Cooled Leading Edge

NASA Technical Reports Server (NTRS)

Glass, David E.

1998-01-01

A set of closed form equations for the preliminary evaluation and design of a heat-pipe-cooled leading edge is presented. The set of equations can provide a leading-edge designer with a quick evaluation of the feasibility of using heat-pipe cooling. The heat pipes can be embedded in a metallic or composite structure. The maximum heat flux, total integrated heat load, and thermal properties of the structure and heat-pipe container are required input. The heat-pipe operating temperature, maximum surface temperature, heat-pipe length, and heat pipe-spacing can be estimated. Results using the design equations compared well with those from a 3-D finite element analysis for both a large and small radius leading edge.

12 CFR Appendix H to Part 226 - Closed-End Model Forms and Clauses

Code of Federal Regulations, 2010 CFR

2018-01-01

... Payment Summary Model Clause (§ 226.18(s)) H-4(F)—Adjustable-Rate Mortgage or Step-Rate Mortgage Interest Rate and Payment Summary Model Clause (§ 226.18(s)) H-4(G)—Mortgage with Negative Amortization Interest Rate and Payment Summary Model Clause (§ 226.18(s)) H-4(H)—Fixed-Rate Mortgage with Interest-Only...

Dynamic simulation of perturbation responses in a closed-loop virtual arm model.

PubMed

Du, Yu-Fan; He, Xin; Lan, Ning

2010-01-01

A closed-loop virtual arm (VA) model has been developed in SIMULINK environment by adding spinal reflex circuits and propriospinal neural networks to the open-loop VA model developed in early study [1]. An improved virtual muscle model (VM4.0) is used to speed up simulation and to generate more precise recruitment of muscle force at low levels of muscle activation. Time delays in the reflex loops are determined by their synaptic connections and afferent transmission back to the spinal cord. Reflex gains are properly selected so that closed-loop responses are stable. With the closed-loop VA model, we are developing an approach to evaluate system behaviors by dynamic simulation of perturbation responses. Joint stiffness is calculated based on simulated perturbation responses by a least-squares algorithm in MATLAB. This method of dynamic simulation will be essential for further evaluation of feedforward and reflex control of arm movement and position.

16 CFR 313.2 - Model privacy form and examples.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 16 Commercial Practices 1 2013-01-01 2013-01-01 false Model privacy form and examples. 313.2... PRIVACY OF CONSUMER FINANCIAL INFORMATION § 313.2 Model privacy form and examples. (a) Model privacy form. Use of the model privacy form in appendix A of this part, consistent with the instructions in appendix...

16 CFR 313.2 - Model privacy form and examples.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 16 Commercial Practices 1 2012-01-01 2012-01-01 false Model privacy form and examples. 313.2... PRIVACY OF CONSUMER FINANCIAL INFORMATION § 313.2 Model privacy form and examples. (a) Model privacy form. Use of the model privacy form in appendix A of this part, consistent with the instructions in appendix...

16 CFR 313.2 - Model privacy form and examples.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 16 Commercial Practices 1 2014-01-01 2014-01-01 false Model privacy form and examples. 313.2... PRIVACY OF CONSUMER FINANCIAL INFORMATION § 313.2 Model privacy form and examples. (a) Model privacy form. Use of the model privacy form in appendix A of this part, consistent with the instructions in appendix...

17 CFR 160.2 - Model privacy form and examples.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 17 Commodity and Securities Exchanges 1 2011-04-01 2011-04-01 false Model privacy form and... PRIVACY OF CONSUMER FINANCIAL INFORMATION § 160.2 Model privacy form and examples. (a) Model privacy form. Use of the model privacy form in appendix A of this part, consistent with the instructions in appendix...

16 CFR 313.2 - Model privacy form and examples.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 16 Commercial Practices 1 2011-01-01 2011-01-01 false Model privacy form and examples. 313.2... PRIVACY OF CONSUMER FINANCIAL INFORMATION § 313.2 Model privacy form and examples. (a) Model privacy form. Use of the model privacy form in appendix A of this part, consistent with the instructions in appendix...

17 CFR 160.2 - Model privacy form and examples.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 17 Commodity and Securities Exchanges 1 2010-04-01 2010-04-01 false Model privacy form and... PRIVACY OF CONSUMER FINANCIAL INFORMATION § 160.2 Model privacy form and examples. (a) Model privacy form. Use of the model privacy form in appendix A of this part, consistent with the instructions in appendix...

16 CFR 313.2 - Model privacy form and examples.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 16 Commercial Practices 1 2010-01-01 2010-01-01 false Model privacy form and examples. 313.2... PRIVACY OF CONSUMER FINANCIAL INFORMATION § 313.2 Model privacy form and examples. (a) Model privacy form. Use of the model privacy form in appendix A of this part, consistent with the instructions in appendix...

A New Closed Form Approximation for BER for Optical Wireless Systems in Weak Atmospheric Turbulence

NASA Astrophysics Data System (ADS)

Kaushik, Rahul; Khandelwal, Vineet; Jain, R. C.

2018-04-01

Weak atmospheric turbulence condition in an optical wireless communication (OWC) is captured by log-normal distribution. The analytical evaluation of average bit error rate (BER) of an OWC system under weak turbulence is intractable as it involves the statistical averaging of Gaussian Q-function over log-normal distribution. In this paper, a simple closed form approximation for BER of OWC system under weak turbulence is given. Computation of BER for various modulation schemes is carried out using proposed expression. The results obtained using proposed expression compare favorably with those obtained using Gauss-Hermite quadrature approximation and Monte Carlo Simulations.

12 CFR 332.2 - Model privacy form and examples.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 12 Banks and Banking 5 2012-01-01 2012-01-01 false Model privacy form and examples. 332.2 Section... POLICY PRIVACY OF CONSUMER FINANCIAL INFORMATION § 332.2 Model privacy form and examples. (a) Model privacy form. Use of the model privacy form in appendix A of this part, consistent with the instructions...

12 CFR 216.2 - Model privacy form and examples.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 12 Banks and Banking 2 2014-01-01 2014-01-01 false Model privacy form and examples. 216.2 Section... PRIVACY OF CONSUMER FINANCIAL INFORMATION (REGULATION P) § 216.2 Model privacy form and examples. (a) Model privacy form. Use of the model privacy form in appendix A of this part, consistent with the...

17 CFR 160.2 - Model privacy form and examples.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 17 Commodity and Securities Exchanges 1 2013-04-01 2013-04-01 false Model privacy form and... PRIVACY OF CONSUMER FINANCIAL INFORMATION UNDER TITLE V OF THE GRAMM-LEACH-BLILEY ACT § 160.2 Model privacy form and examples. (a) Model privacy form. Use of the model privacy form in appendix A of this...

12 CFR 332.2 - Model privacy form and examples.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 12 Banks and Banking 5 2014-01-01 2014-01-01 false Model privacy form and examples. 332.2 Section... POLICY PRIVACY OF CONSUMER FINANCIAL INFORMATION § 332.2 Model privacy form and examples. (a) Model privacy form. Use of the model privacy form in appendix A of this part, consistent with the instructions...

12 CFR 216.2 - Model privacy form and examples.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 12 Banks and Banking 2 2012-01-01 2012-01-01 false Model privacy form and examples. 216.2 Section... PRIVACY OF CONSUMER FINANCIAL INFORMATION (REGULATION P) § 216.2 Model privacy form and examples. (a) Model privacy form. Use of the model privacy form in appendix A of this part, consistent with the...

17 CFR 160.2 - Model privacy form and examples.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 17 Commodity and Securities Exchanges 1 2012-04-01 2012-04-01 false Model privacy form and... PRIVACY OF CONSUMER FINANCIAL INFORMATION UNDER TITLE V OF THE GRAMM-LEACH-BLILEY ACT § 160.2 Model privacy form and examples. (a) Model privacy form. Use of the model privacy form in appendix A of this...

12 CFR 716.2 - Model privacy form and examples.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 12 Banks and Banking 7 2013-01-01 2013-01-01 false Model privacy form and examples. 716.2 Section... PRIVACY OF CONSUMER FINANCIAL INFORMATION § 716.2 Model privacy form and examples. (a) Model privacy form. Use of the model privacy form in Appendix A of this part, consistent with the instructions in Appendix...

12 CFR 216.2 - Model privacy form and examples.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 12 Banks and Banking 2 2013-01-01 2013-01-01 false Model privacy form and examples. 216.2 Section... PRIVACY OF CONSUMER FINANCIAL INFORMATION (REGULATION P) § 216.2 Model privacy form and examples. (a) Model privacy form. Use of the model privacy form in appendix A of this part, consistent with the...

12 CFR 332.2 - Model privacy form and examples.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 12 Banks and Banking 4 2011-01-01 2011-01-01 false Model privacy form and examples. 332.2 Section... POLICY PRIVACY OF CONSUMER FINANCIAL INFORMATION § 332.2 Model privacy form and examples. (a) Model privacy form. Use of the model privacy form in Appendix A of this part, consistent with the instructions...

17 CFR 160.2 - Model privacy form and examples.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 17 Commodity and Securities Exchanges 2 2014-04-01 2014-04-01 false Model privacy form and... (CONTINUED) PRIVACY OF CONSUMER FINANCIAL INFORMATION UNDER TITLE V OF THE GRAMM-LEACH-BLILEY ACT § 160.2 Model privacy form and examples. (a) Model privacy form. Use of the model privacy form in appendix A of...

12 CFR 716.2 - Model privacy form and examples.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 12 Banks and Banking 7 2012-01-01 2012-01-01 false Model privacy form and examples. 716.2 Section... PRIVACY OF CONSUMER FINANCIAL INFORMATION § 716.2 Model privacy form and examples. (a) Model privacy form. Use of the model privacy form in Appendix A of this part, consistent with the instructions in Appendix...

12 CFR 332.2 - Model privacy form and examples.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 12 Banks and Banking 5 2013-01-01 2013-01-01 false Model privacy form and examples. 332.2 Section... POLICY PRIVACY OF CONSUMER FINANCIAL INFORMATION § 332.2 Model privacy form and examples. (a) Model privacy form. Use of the model privacy form in appendix A of this part, consistent with the instructions...

12 CFR 216.2 - Model privacy form and examples.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 12 Banks and Banking 2 2011-01-01 2011-01-01 false Model privacy form and examples. 216.2 Section... PRIVACY OF CONSUMER FINANCIAL INFORMATION (REGULATION P) § 216.2 Model privacy form and examples. (a) Model privacy form. Use of the model privacy form in appendix A of this part, consistent with the...

12 CFR 216.2 - Model privacy form and examples.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 12 Banks and Banking 2 2010-01-01 2010-01-01 false Model privacy form and examples. 216.2 Section... PRIVACY OF CONSUMER FINANCIAL INFORMATION (REGULATION P) § 216.2 Model privacy form and examples. (a) Model privacy form. Use of the model privacy form in appendix A of this part, consistent with the...

12 CFR 332.2 - Model privacy form and examples.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 12 Banks and Banking 4 2010-01-01 2010-01-01 false Model privacy form and examples. 332.2 Section... POLICY PRIVACY OF CONSUMER FINANCIAL INFORMATION § 332.2 Model privacy form and examples. (a) Model privacy form. Use of the model privacy form in Appendix A of this part, consistent with the instructions...

12 CFR 716.2 - Model privacy form and examples.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Model privacy form and examples. 716.2 Section... PRIVACY OF CONSUMER FINANCIAL INFORMATION § 716.2 Model privacy form and examples. (a) Model privacy form. Use of the model privacy form in Appendix A of this part, consistent with the instructions in Appendix...

31 CFR 50.17 - Use of model forms.

Code of Federal Regulations, 2010 CFR

2010-07-01

... requirement if it uses NAIC Model Disclosure Form No. 2. (2) An insurer that is required to make the... with the disclosure requirement if it uses NAIC Model Disclosure Form No. 1. Such an insurer may also use the same NAIC Model Disclosure Form No. 1 to comply with the notice requirement of section 105(c...

12 CFR 716.2 - Model privacy form and examples.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 12 Banks and Banking 6 2011-01-01 2011-01-01 false Model privacy form and examples. 716.2 Section... PRIVACY OF CONSUMER FINANCIAL INFORMATION § 716.2 Model privacy form and examples. (a) Model privacy form. Use of the model privacy form in appendixA of this part, consistent with the instructions in appendixA...

On Closed Shells in Nuclei

DOE R&D Accomplishments Database

Mayer, M. G.

1948-02-01

It has been suggested in the past that special numbers of neutrons or protons in the nucleus form a particularly stable configuration.{sup1} The complete evidence for this has never been summarized, nor is it generally recognized how convincing this evidence is. That 20 neutrons or protons (Ca{sup40}) form a closed shell is predicted by the Hartree model. A number of calculations support this fact.{sup2} These considerations will not be repeated here. In this paper, the experimental facts indicating a particular stability of shells of 50 and 82 protons and of 50, 82, and 126 neutrons will be listed.

A classical model for closed-loop diagrams of binary liquid mixtures

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schnitzler, J.v.; Prausnitz, J.M.

1994-03-01

A classical lattice model for closed-loop temperature-composition phase diagrams has been developed. It considers the effect of specific interactions, such as hydrogen bonding, between dissimilar components. This van Laar-type model includes a Flory-Huggins term for the excess entropy of mixing. It is applied to several liquid-liquid equilibria of nonelectrolytes, where the molecules of the two components differ in size. The model is able to represent the observed data semi-quantitatively, but in most cases it is not flexible enough to predict all parts of the closed loop quantitatively. The ability of the model to represent different binary systems is discussed. Finally,more » attention is given to a correction term, concerning the effect of concentration fluctuations near the upper critical solution temperature.« less

Art form as an object of cognitive modeling (towards development of Vygotsky`s semiotic model)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dmitriev, V.; Perlovsky, L.I.

1996-12-31

We suggest a further development of Vygotsky`s esthetic-semiotic model. First, we discuss Vygotsky`s model originally developed for the analysis of Ivan Bunin`s story {open_quotes}Light Breath{close_quotes}. Vygotsky analyzes formal methods used by Bunin to achieve a specific esthetic effect of {open_quote}lightness{close_quotes} while describing {open_quotes}dirty{close_quotes} events of everyday life. According to Vygotsky, this effect is achieved by ordering of events in a non-linear fashion. Vygotsky creams an airy pattern of smooth lines connecting events of story that he first orders linearly in time. And, he insists that this airy pattern creates an impression of airy lightness. In the language of semiotics, themore » esthetic effect is created by a specific structural organization of signs. Second, we present our critique of Vygotsky`s model. Although, we do not agree with Vygotsky`s sometimes moralistic judgements, and we consider the dynamics between inner personal values and received moral values to be more complicated than implied in his judgements, our critique in this paper is limited to the structure of his semiotic model. We emphasize that Vygotsky`s model does not explicitly account for a hierarchy of multiple levels of semiotic analysis. His analysis regularly slips from one level to another: (1) a lever of cognitive perception by a regular reader is confused with a level of creative genius of a writer; (2) {open_quotes}open{close_quotes} time of real world is mixed up with {open_quote}closed{close_quote} time of the story; (3) events are not organized by the hierarchy of their importance, nor in real world, nor in the inner model of the personages, nor in the story.« less

Periodic and Aperiodic Close Packing: A Spontaneous Hard-Sphere Model.

ERIC Educational Resources Information Center

van de Waal, B. W.

1985-01-01

Shows how to make close-packed models from balloons and table tennis balls to illustrate structural features of clusters and organometallic cluster-compounds (which are of great interest in the study of chemical reactions). These models provide a very inexpensive and tactile illustration of the organization of matter for concrete operational…

Modeling Gas Exchange in a Closed Plant Growth Chamber

NASA Technical Reports Server (NTRS)

Cornett, J. D.; Hendrix, J. E.; Wheeler, R. M.; Ross, C. W.; Sadeh, W. Z.

1994-01-01

Fluid transport models for fluxes of water vapor and CO2 have been developed for one crop of wheat and three crops of soybean grown in a closed plant a growth chamber. Correspondence among these fluxes is discussed. Maximum fluxes of gases are provided for engineering design requirements of fluid recycling equipment in growth chambers. Furthermore, to investigate the feasibility of generalized crop models, dimensionless representations of water vapor fluxes are presented. The feasibility of such generalized models and the need for additional data are discussed.

Modeling gas exchange in a closed plant growth chamber

NASA Technical Reports Server (NTRS)

Cornett, J. D.; Hendrix, J. E.; Wheeler, R. M.; Ross, C. W.; Sadeh, W. Z.

1994-01-01

Fluid transport models for fluxes of water vapor and CO2 have been developed for one crop of wheat and three crops of soybean grown in a closed plant growth chamber. Correspondence among these fluxes is discussed. Maximum fluxes of gases are provided for engineering design requirements of fluid recycling equipment in growth chambers. Furthermore, to investigate the feasibility of generalized crop models, dimensionless representations of water vapor fluxes are presented. The feasibility of such generalized models and the need for additional data are discussed.

Modeling Production Plant Forming Processes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rhee, M; Becker, R; Couch, R

2004-09-22

Engineering has simulation tools and experience in modeling forming processes. Y-12 personnel have expressed interest in validating our tools and experience against their manufacturing process activities such as rolling, casting, and forging etc. We have demonstrated numerical capabilities in a collaborative DOE/OIT project with ALCOA that is nearing successful completion. The goal was to use ALE3D to model Alcoa's slab rolling process in order to demonstrate a computational tool that would allow Alcoa to define a rolling schedule that would minimize the probability of ingot fracture, thus reducing waste and energy consumption. It is intended to lead to long-term collaborationmore » with Y-12 and perhaps involvement with other components of the weapons production complex. Using simulations to aid in design of forming processes can: decrease time to production; reduce forming trials and associated expenses; and guide development of products with greater uniformity and less scrap.« less

Effects of urban form on the urban heat island effect based on spatial regression model.

PubMed

Yin, Chaohui; Yuan, Man; Lu, Youpeng; Huang, Yaping; Liu, Yanfang

2018-09-01

The urban heat island (UHI) effect is becoming more of a concern with the accelerated process of urbanization. However, few studies have examined the effect of urban form on land surface temperature (LST) especially from an urban planning perspective. This paper used spatial regression model to investigate the effects of both land use composition and urban form on LST in Wuhan City, China, based on the regulatory planning management unit. Landsat ETM+ image data was used to estimate LST. Land use composition was calculated by impervious surface area proportion, vegetated area proportion, and water proportion, while urban form indicators included sky view factor (SVF), building density, and floor area ratio (FAR). We first tested for spatial autocorrelation of urban LST, which confirmed that a traditional regression method would be invalid. A spatial error model (SEM) was chosen because its parameters were better than a spatial lag model (SLM). The results showed that urban form metrics should be the focus for mitigation efforts of UHI effects. In addition, analysis of the relationship between urban form and UHI effect based on the regulatory planning management unit was helpful for promoting corresponding UHI effect mitigation rules in practice. Finally, the spatial regression model was recommended to be an appropriate method for dealing with problems related to the urban thermal environment. Results suggested that the impact of urbanization on the UHI effect can be mitigated not only by balancing various land use types, but also by optimizing urban form, which is even more effective. This research expands the scientific understanding of effects of urban form on UHI by explicitly analyzing indicators closely related to urban detailed planning at the level of regulatory planning management unit. In addition, it may provide important insights and effective regulation measures for urban planners to mitigate future UHI effects. Copyright © 2018 Elsevier B.V. All

Emotional closeness to parents and grandparents: A moderated mediation model predicting adolescent adjustment.

PubMed

Attar-Schwartz, Shalhevet

2015-09-01

Warm and emotionally close relationships with parents and grandparents have been found in previous studies to be linked with better adolescent adjustment. The present study, informed by Family Systems Theory and Intergenerational Solidarity Theory, uses a moderated mediation model analyzing the contribution of the dynamics of these intergenerational relationships to adolescent adjustment. Specifically, it examines the mediating role of emotional closeness to the closest grandparent in the relationship between emotional closeness to a parent (the offspring of the closest grandparent) and adolescent adjustment difficulties. The model also examines the moderating role of emotional closeness to parents in the relationship between emotional closeness to grandparents and adjustment difficulties. The study was based on a sample of 1,405 Jewish Israeli secondary school students (ages 12-18) who completed a structured questionnaire. It was found that emotional closeness to the closest grandparent was more strongly associated with reduced adjustment difficulties among adolescents with higher levels of emotional closeness to their parents. In addition, adolescent adjustment and emotional closeness to parents was partially mediated by emotional closeness to grandparents. Examining the family conditions under which adolescents' relationships with grandparents is stronger and more beneficial for them can help elucidate variations in grandparent-grandchild ties and expand our understanding of the mechanisms that shape child outcomes. (c) 2015 APA, all rights reserved).

Enabling comparative modeling of closely related genomes: Example genus Brucella

DOE PAGES

Faria, José P.; Edirisinghe, Janaka N.; Davis, James J.; ...

2014-03-08

For many scientific applications, it is highly desirable to be able to compare metabolic models of closely related genomes. In this study, we attempt to raise awareness to the fact that taking annotated genomes from public repositories and using them for metabolic model reconstructions is far from being trivial due to annotation inconsistencies. We are proposing a protocol for comparative analysis of metabolic models on closely related genomes, using fifteen strains of genus Brucella, which contains pathogens of both humans and livestock. This study lead to the identification and subsequent correction of inconsistent annotations in the SEED database, as wellmore » as the identification of 31 biochemical reactions that are common to Brucella, which are not originally identified by automated metabolic reconstructions. We are currently implementing this protocol for improving automated annotations within the SEED database and these improvements have been propagated into PATRIC, Model-SEED, KBase and RAST. This method is an enabling step for the future creation of consistent annotation systems and high-quality model reconstructions that will support in predicting accurate phenotypes such as pathogenicity, media requirements or type of respiration.« less

Enabling comparative modeling of closely related genomes: Example genus Brucella

DOE Office of Scientific and Technical Information (OSTI.GOV)

Faria, José P.; Edirisinghe, Janaka N.; Davis, James J.

For many scientific applications, it is highly desirable to be able to compare metabolic models of closely related genomes. In this study, we attempt to raise awareness to the fact that taking annotated genomes from public repositories and using them for metabolic model reconstructions is far from being trivial due to annotation inconsistencies. We are proposing a protocol for comparative analysis of metabolic models on closely related genomes, using fifteen strains of genus Brucella, which contains pathogens of both humans and livestock. This study lead to the identification and subsequent correction of inconsistent annotations in the SEED database, as wellmore » as the identification of 31 biochemical reactions that are common to Brucella, which are not originally identified by automated metabolic reconstructions. We are currently implementing this protocol for improving automated annotations within the SEED database and these improvements have been propagated into PATRIC, Model-SEED, KBase and RAST. This method is an enabling step for the future creation of consistent annotation systems and high-quality model reconstructions that will support in predicting accurate phenotypes such as pathogenicity, media requirements or type of respiration.« less

Hencky's model for elastomer forming process

NASA Astrophysics Data System (ADS)

Oleinikov, A. A.; Oleinikov, A. I.

2016-08-01

In the numerical simulation of elastomer forming process, Henckys isotropic hyperelastic material model can guarantee relatively accurate prediction of strain range in terms of large deformations. It is shown, that this material model prolongate Hooke's law from the area of infinitesimal strains to the area of moderate ones. New representation of the fourth-order elasticity tensor for Hencky's hyperelastic isotropic material is obtained, it possesses both minor symmetries, and the major symmetry. Constitutive relations of considered model is implemented into MSC.Marc code. By calculating and fitting curves, the polyurethane elastomer material constants are selected. Simulation of equipment for elastomer sheet forming are considered.

Microstructure-based hyperelastic models for closed-cell solids

PubMed Central

Wyatt, Hayley

2017-01-01

For cellular bodies involving large elastic deformations, mesoscopic continuum models that take into account the interplay between the geometry and the microstructural responses of the constituents are developed, analysed and compared with finite-element simulations of cellular structures with different architecture. For these models, constitutive restrictions for the physical plausibility of the material responses are established, and global descriptors such as nonlinear elastic and shear moduli and Poisson’s ratio are obtained from the material characteristics of the constituents. Numerical results show that these models capture well the mechanical responses of finite-element simulations for three-dimensional periodic structures of neo-Hookean material with closed cells under large tension. In particular, the mesoscopic models predict the macroscopic stiffening of the structure when the stiffness of the cell-core increases. PMID:28484340

Microstructure-based hyperelastic models for closed-cell solids.

PubMed

Mihai, L Angela; Wyatt, Hayley; Goriely, Alain

2017-04-01

For cellular bodies involving large elastic deformations, mesoscopic continuum models that take into account the interplay between the geometry and the microstructural responses of the constituents are developed, analysed and compared with finite-element simulations of cellular structures with different architecture. For these models, constitutive restrictions for the physical plausibility of the material responses are established, and global descriptors such as nonlinear elastic and shear moduli and Poisson's ratio are obtained from the material characteristics of the constituents. Numerical results show that these models capture well the mechanical responses of finite-element simulations for three-dimensional periodic structures of neo-Hookean material with closed cells under large tension. In particular, the mesoscopic models predict the macroscopic stiffening of the structure when the stiffness of the cell-core increases.

Microstructure-based hyperelastic models for closed-cell solids

NASA Astrophysics Data System (ADS)

Mihai, L. Angela; Wyatt, Hayley; Goriely, Alain

2017-04-01

For cellular bodies involving large elastic deformations, mesoscopic continuum models that take into account the interplay between the geometry and the microstructural responses of the constituents are developed, analysed and compared with finite-element simulations of cellular structures with different architecture. For these models, constitutive restrictions for the physical plausibility of the material responses are established, and global descriptors such as nonlinear elastic and shear moduli and Poisson's ratio are obtained from the material characteristics of the constituents. Numerical results show that these models capture well the mechanical responses of finite-element simulations for three-dimensional periodic structures of neo-Hookean material with closed cells under large tension. In particular, the mesoscopic models predict the macroscopic stiffening of the structure when the stiffness of the cell-core increases.

12 CFR 1016.2 - Model privacy form and examples.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 12 Banks and Banking 8 2013-01-01 2013-01-01 false Model privacy form and examples. 1016.2 Section 1016.2 Banks and Banking BUREAU OF CONSUMER FINANCIAL PROTECTION PRIVACY OF CONSUMER FINANCIAL INFORMATION (REGULATION P) § 1016.2 Model privacy form and examples. (a) Model privacy form. Use of the model...

12 CFR 1016.2 - Model privacy form and examples.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 12 Banks and Banking 8 2014-01-01 2014-01-01 false Model privacy form and examples. 1016.2 Section 1016.2 Banks and Banking BUREAU OF CONSUMER FINANCIAL PROTECTION PRIVACY OF CONSUMER FINANCIAL INFORMATION (REGULATION P) § 1016.2 Model privacy form and examples. (a) Model privacy form. Use of the model...

12 CFR 1016.2 - Model privacy form and examples.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 12 Banks and Banking 8 2012-01-01 2012-01-01 false Model privacy form and examples. 1016.2 Section 1016.2 Banks and Banking BUREAU OF CONSUMER FINANCIAL PROTECTION PRIVACY OF CONSUMER FINANCIAL INFORMATION (REGULATION P) § 1016.2 Model privacy form and examples. (a) Model privacy form. Use of the model...

MSC/NASTRAN DMAP Alter Used for Closed-Form Static Analysis With Inertia Relief and Displacement-Dependent Loads

NASA Technical Reports Server (NTRS)

1996-01-01

Solving for the displacements of free-free coupled systems acted upon by static loads is a common task in the aerospace industry. Often, these problems are solved by static analysis with inertia relief. This technique allows for a free-free static analysis by balancing the applied loads with the inertia loads generated by the applied loads. For some engineering applications, the displacements of the free-free coupled system induce additional static loads. Hence, the applied loads are equal to the original loads plus the displacement-dependent loads. A launch vehicle being acted upon by an aerodynamic loading can have such applied loads. The final displacements of such systems are commonly determined with iterative solution techniques. Unfortunately, these techniques can be time consuming and labor intensive. Because the coupled system equations for free-free systems with displacement-dependent loads can be written in closed form, it is advantageous to solve for the displacements in this manner. Implementing closed-form equations in static analysis with inertia relief is analogous to implementing transfer functions in dynamic analysis. An MSC/NASTRAN (MacNeal-Schwendler Corporation/NASA Structural Analysis) DMAP (Direct Matrix Abstraction Program) Alter was used to include displacement-dependent loads in static analysis with inertia relief. It efficiently solved a common aerospace problem that typically has been solved with an iterative technique.

12 CFR 573.2 - Model privacy form and examples.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 12 Banks and Banking 6 2014-01-01 2012-01-01 true Model privacy form and examples. 573.2 Section 573.2 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY PRIVACY OF CONSUMER FINANCIAL INFORMATION § 573.2 Model privacy form and examples. (a) Model privacy form. Use of the model...

12 CFR 40.2 - Model privacy form and examples.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 12 Banks and Banking 1 2011-01-01 2011-01-01 false Model privacy form and examples. 40.2 Section 40.2 Banks and Banking COMPTROLLER OF THE CURRENCY, DEPARTMENT OF THE TREASURY PRIVACY OF CONSUMER FINANCIAL INFORMATION § 40.2 Model privacy form and examples. (a) Model privacy form. Use of the model...

12 CFR 573.2 - Model privacy form and examples.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 12 Banks and Banking 5 2011-01-01 2011-01-01 false Model privacy form and examples. 573.2 Section 573.2 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY PRIVACY OF CONSUMER FINANCIAL INFORMATION § 573.2 Model privacy form and examples. (a) Model privacy form. Use of the model...

12 CFR 40.2 - Model privacy form and examples.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 12 Banks and Banking 1 2014-01-01 2014-01-01 false Model privacy form and examples. 40.2 Section 40.2 Banks and Banking COMPTROLLER OF THE CURRENCY, DEPARTMENT OF THE TREASURY PRIVACY OF CONSUMER FINANCIAL INFORMATION § 40.2 Model privacy form and examples. (a) Model privacy form. Use of the model...

12 CFR 40.2 - Model privacy form and examples.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 12 Banks and Banking 1 2013-01-01 2013-01-01 false Model privacy form and examples. 40.2 Section 40.2 Banks and Banking COMPTROLLER OF THE CURRENCY, DEPARTMENT OF THE TREASURY PRIVACY OF CONSUMER FINANCIAL INFORMATION § 40.2 Model privacy form and examples. (a) Model privacy form. Use of the model...

12 CFR 573.2 - Model privacy form and examples.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 12 Banks and Banking 6 2012-01-01 2012-01-01 false Model privacy form and examples. 573.2 Section 573.2 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY PRIVACY OF CONSUMER FINANCIAL INFORMATION § 573.2 Model privacy form and examples. (a) Model privacy form. Use of the model...

12 CFR 573.2 - Model privacy form and examples.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 12 Banks and Banking 6 2013-01-01 2012-01-01 true Model privacy form and examples. 573.2 Section 573.2 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY PRIVACY OF CONSUMER FINANCIAL INFORMATION § 573.2 Model privacy form and examples. (a) Model privacy form. Use of the model...

12 CFR 40.2 - Model privacy form and examples.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 12 Banks and Banking 1 2012-01-01 2012-01-01 false Model privacy form and examples. 40.2 Section 40.2 Banks and Banking COMPTROLLER OF THE CURRENCY, DEPARTMENT OF THE TREASURY PRIVACY OF CONSUMER FINANCIAL INFORMATION § 40.2 Model privacy form and examples. (a) Model privacy form. Use of the model...

12 CFR 40.2 - Model privacy form and examples.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 12 Banks and Banking 1 2010-01-01 2010-01-01 false Model privacy form and examples. 40.2 Section 40.2 Banks and Banking COMPTROLLER OF THE CURRENCY, DEPARTMENT OF THE TREASURY PRIVACY OF CONSUMER FINANCIAL INFORMATION § 40.2 Model privacy form and examples. (a) Model privacy form. Use of the model...

12 CFR 573.2 - Model privacy form and examples.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Model privacy form and examples. 573.2 Section 573.2 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY PRIVACY OF CONSUMER FINANCIAL INFORMATION § 573.2 Model privacy form and examples. (a) Model privacy form. Use of the model...

The role of shape complexity in the detection of closed contours.

PubMed

Wilder, John; Feldman, Jacob; Singh, Manish

2016-09-01

The detection of contours in noise has been extensively studied, but the detection of closed contours, such as the boundaries of whole objects, has received relatively little attention. Closed contours pose substantial challenges not present in the simple (open) case, because they form the outlines of whole shapes and thus take on a range of potentially important configural properties. In this paper we consider the detection of closed contours in noise as a probabilistic decision problem. Previous work on open contours suggests that contour complexity, quantified as the negative log probability (Description Length, DL) of the contour under a suitably chosen statistical model, impairs contour detectability; more complex (statistically surprising) contours are harder to detect. In this study we extended this result to closed contours, developing a suitable probabilistic model of whole shapes that gives rise to several distinct though interrelated measures of shape complexity. We asked subjects to detect either natural shapes (Exp. 1) or experimentally manipulated shapes (Exp. 2) embedded in noise fields. We found systematic effects of global shape complexity on detection performance, demonstrating how aspects of global shape and form influence the basic process of object detection. Copyright © 2015 Elsevier Ltd. All rights reserved.

A closed form, physical optics expression for the radar cross section of a perfectly conducting flat plate over a dielectric half-space

NASA Astrophysics Data System (ADS)

Anastassiu, Hristos T.

2003-04-01

The physical optics approximation is employed in the derivation of a closed form expression for the radar cross section (RCS) of a flat, perfectly conducting plate of various shapes, located over a dielectric, possibly lossy half-space. The half-space is assumed to lie in the far field region of the plate. The well-known "four-path model" is invoked in a first-order approximation of the half-space contribution to the scattering mechanisms. Numerical results are compared to a reference, Moment Method solution, and the agreement is investigated, to assess the accuracy of the approximations used. The analytical expressions derived can facilitate very fast RCS calculations for realistic scatterers, such as ships in a sea environment, or aircraft flying low over the ground.

Kinetics of color development of melanoidins formed from fructose/amino acid model systems.

PubMed

Echavarría, A P; Pagán, J; Ibarz, A

2014-03-01

The formation of soluble melanoidins from a single combination of sugar (fructose) and amino acid model systems were evaluated kinetically. The selected amino acids, commonly found in apple juice and highly reactive in the Maillard reaction, were asparagine, aspartic acid, and glutamic acid. The effect of these reagents and the treatment at different temperatures (50 , 85 , and 100 ) during 96 h on the color intensity of the melanoidin formed was measured by absorbance at different wavelengths (280, 325, 405, and 420 nm). The absorbance of the melanoidin formed from all model systems was located on the wavelength of 405 nm, that is, the area of the visible spectrum close to the UV region. The color of the melanoidins was directly measured using the CIELAB color space system. A first-order kinetic model was applied to the evolution of the ΔE * (color difference) and L * (lightness) of the color. The fructose/aspartic acid model system values of a * (redness) and b * (yellowness) were found in the brown-red zone. Therefore, the color development of the melanoidins was influenced by the type of amino acid and temperature. Especially, it is thought that the a * and b * values can be used to explain the differences among the amino acids in the color development of melanoidins.

An approximate closed-form solution for lead lag damping of rotor blades in hover

NASA Technical Reports Server (NTRS)

Peters, D. A.

1975-01-01

Simple stability methods are used to derive an approximate, closed-form expression for the lead-lag damping of rotor blades in hover. Destabilizing terms are shown to be a result of two dynamic mechanisms. First, the destabilizing aerodynamic forces that can occur when blade lift is higher than a critical value are maximized when the blade motion is in a straight line equidistant from the blade chord and the average direction of the air flow velocity. This condition occurs when the Coriolis terms vanish and when the elastic coupling terms align the blade motion with this least stable direction. Second, the nonconservative stiffness terms that result from pitch-flap or pitch-lag coupling can add or subtract energy from the system depending upon whether the motion of the blade tip is clockwise or counterclockwise.

Cognitive processes and conflict in close relationships: an attribution-efficacy model.

PubMed

Fincham, F D; Bradbury, T N

1987-12-01

A recently proposed model of cognitive processes underlying conflict in close relationships (Doherty, 1978, 1981a, 1981b) is revised and tested in two studies. Central to the original model are the causal attributions made for conflict and the perceived efficacy or ability to resolve conflict. The model is revised to incorporate judgments of responsibility and to provide a closer link to self-efficacy theory. The first study examines attributions and efficacy expectations in mother-child relationships. As anticipated, only weak evidence was obtained for predictions retained from the original model, high-lighting the relationship-specific nature of cognitive processes for conflict in families. A second study examines husband-wife relationships and provides evidence for the usefulness of an attribution-efficacy model for marital conflict. The attributional component of the model received greater support than that pertaining to efficacy expectations. In both studies, support was obtained for the proposal that the relation between conflict dimensions (e.g., blame) and causal dimensions is mediated by judgments of responsibility. The significance of the revisions to Doherty's model for understanding conflict in close relationships is discussed, and several avenues for further research are outlined.

A Tissue Propagation Model for Validating Close-Proximity Biomedical Radiometer Measurements

NASA Technical Reports Server (NTRS)

Bonds, Q.; Herzig, P.; Weller, T.

2016-01-01

The propagation of thermally-generated electromagnetic emissions through stratified human tissue is studied herein using a non-coherent mathematical model. The model is developed to complement subsurface body temperature measurements performed using a close proximity microwave radiometer. The model takes into account losses and reflections as thermal emissions propagate through the body, before being emitted at the skin surface. The derivation is presented in four stages and applied to the human core phantom, a physical representation of a stomach volume of skin, muscle, and blood-fatty tissue. A drop in core body temperature is simulated via the human core phantom and the response of the propagation model is correlated to the radiometric measurement. The results are comparable, with differences on the order of 1.5 - 3%. Hence the plausibility of core body temperature extraction via close proximity radiometry is demonstrated, given that the electromagnetic characteristics of the stratified tissue layers are known.

A New Model of Tracheostomy Care: Closing the Research-Practice Gap

DTIC Science & Technology

2003-01-01

521 A New Model of Tracheostomy Care: Closing the Research –Practice Gap Joel St. Clair Abstract Performance improvements have brought about...and it continues to close the research - practice gap . The WRAMC Department of Nursing is presently developing similar evidence-based procedures for... Research -Practice Gap 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK

17 CFR 248.2 - Model privacy form: rule of construction.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Model privacy form: rule of... Safeguarding Personal Information § 248.2 Model privacy form: rule of construction. (a) Model privacy form. Use of the model privacy form in Appendix A to Subpart A of this part, consistent with the instructions...

Mathematical form models of tree trunks

Treesearch

Rudolfs Ozolins

2000-01-01

Assortment structure analysis of tree trunks is a characteristic and proper problem that can be solved by using mathematical modeling and standard computer programs. Mathematical form model of tree trunks consists of tapering curve equations and their parameters. Parameters for nine species were obtained by processing measurements of 2,794 model trees and studying the...

Novel Model of Frontal Impact Closed Head Injury in the Rat

PubMed Central

Kilbourne, Michael; Kuehn, Reed; Tosun, Cigdem; Caridi, John; Keledjian, Kaspar; Bochicchio, Grant; Scalea, Thomas; Gerzanich, Volodymyr

2009-01-01

Abstract Frontal impact, closed head trauma is a frequent cause of traumatic brain injury (TBI) in motor vehicle and sports accidents. Diffuse axonal injury (DAI) is common in humans and experimental animals, and results from shearing forces that develop within the anisotropic brain. Because the specific anisotropic properties of the brain are axis-dependent, the anatomical site where force is applied as well as the resultant acceleration, be it linear, rotational, or some combination, are important determinants of the resulting pattern of brain injury. Available rodent models of closed head injury do not reproduce the frontal impact commonly encountered in humans. Here we describe a new rat model of closed head injury that is a modification of the impact-acceleration model of Marmarou. In our model (the Maryland model), the impact force is applied to the anterior part of the cranium and produces TBI by causing anterior-posterior plus sagittal rotational acceleration of the brain inside the intact cranium. Skull fractures, prolonged apnea, and mortality were absent. The animals exhibited petechial hemorrhages, DAI marked by a bead-like pattern of β-amyloid precursor protein (β-APP) in damaged axons, and widespread upregulation of β-APP in neurons, with regions affected including the orbitofrontal cortex (coup), corpus callosum, caudate, putamen, thalamus, cerebellum, and brainstem. Activated caspase-3 was prominent in hippocampal neurons and Purkinje cells at the grey-white matter junction of the cerebellum. Neurobehavioral dysfunction, manifesting as reduced spontaneous exploration, lasted more than 1 week. We conclude that the Maryland model produces diffuse injuries that may be relevant to human brain injury. PMID:19929375

Couple Infertility: From the Perspective of the Close-Relationship Model.

ERIC Educational Resources Information Center

Higgins, Barbara S.

1990-01-01

Presents Close-Relationship Model as comprehensive framework in which to examine interrelated nature of causes and effects of infertility on marital relationship. Includes these factors: physical and psychological characteristics of both partners; joint, couple characteristics; physical and social environment; and relationship itself. Discusses…

Closed-form analysis of fiber-matrix interface stresses under thermo-mechanical loadings

NASA Technical Reports Server (NTRS)

Naik, Rajiv A.; Crews, John H., Jr.

1992-01-01

Closed form techniques for calculating fiber matrix (FM) interface stresses, using repeating square and diamond regular arrays, were presented for a unidirectional composite under thermo-mechanical loadings. An Airy's stress function micromechanics approach from the literature, developed for calculating overall composite moduli, was extended in the present study to compute FM interface stresses for a unidirectional graphite/epoxy (AS4/3501-6) composite under thermal, longitudinal, transverse, transverse shear, and longitudinal shear loadings. Comparison with finite element results indicate excellent agreement of the FM interface stresses for the square array. Under thermal and longitudinal loading, the square array has the same FM peak stresses as the diamond array. The square array predicted higher stress concentrations under transverse normal and longitudinal shear loadings than the diamond array. Under transverse shear loading, the square array had a higher stress concentration while the diamond array had a higher radial stress concentration. Stress concentration factors under transverse shear and longitudinal shear loadings were very sensitive to fiber volume fraction. The present analysis provides a simple way to calculate accurate FM interface stresses for both the square and diamond array configurations.

Comparison of closed loop model with flight test results

NASA Technical Reports Server (NTRS)

George, F. L.

1981-01-01

An analytic technique capable of predicting the landing characteristics of proposed aircraft configurations in the early stages of design was developed. In this analysis, a linear pilot-aircraft closed loop model was evaluated using experimental data generated with the NT-33 variable stability in-flight simulator. The pilot dynamics are modeled as inner and outer servo loop closures around aircraft pitch attitude, and altitude rate-of-change respectively. The landing flare maneuver is of particular interest as recent experience with military and other highly augmented vehicles shows this task to be relatively demanding, and potentially a critical design point. A unique feature of the pilot model is the incorporation of an internal model of the pilot's desired flight path for the flare maneuver.

Integrated multiple-model adaptive fault identification and reconfigurable fault-tolerant control for Lead-Wing close formation systems

NASA Astrophysics Data System (ADS)

Liu, Chun; Jiang, Bin; Zhang, Ke

2018-03-01

This paper investigates the attitude and position tracking control problem for Lead-Wing close formation systems in the presence of loss of effectiveness and lock-in-place or hardover failure. In close formation flight, Wing unmanned aerial vehicle movements are influenced by vortex effects of the neighbouring Lead unmanned aerial vehicle. This situation allows modelling of aerodynamic coupling vortex-effects and linearisation based on optimal close formation geometry. Linearised Lead-Wing close formation model is transformed into nominal robust H-infinity models with respect to Mach hold, Heading hold, and Altitude hold autopilots; static feedback H-infinity controller is designed to guarantee effective tracking of attitude and position while manoeuvring Lead unmanned aerial vehicle. Based on H-infinity control design, an integrated multiple-model adaptive fault identification and reconfigurable fault-tolerant control scheme is developed to guarantee asymptotic stability of close-loop systems, error signal boundedness, and attitude and position tracking properties. Simulation results for Lead-Wing close formation systems validate the efficiency of the proposed integrated multiple-model adaptive control algorithm.

Atmosphere Behavior in Gas-Closed Mouse-Algal Systems: An Experimental and Modelling Study

NASA Technical Reports Server (NTRS)

Averner, M. M.; Moore, B., III; Bartholomew, I.; Wharton, R.

1985-01-01

A dual approach of mathematical modelling and laboratory experimentation aimed at examining the gas exchange characteristics of artificial animal/plant systems closed to the ambient atmosphere was initiated. The development of control techniques and management strategies for maintaining the atmospheric levels of carbon dioxide and oxygen at physiological levels is examined. A mathematical model simulating the atmospheric behavior in these systems was developed and an experimental gas closed system was constructed. These systems are described and preliminary results are presented.

Normal forms for reduced stochastic climate models

PubMed Central

Majda, Andrew J.; Franzke, Christian; Crommelin, Daan

2009-01-01

The systematic development of reduced low-dimensional stochastic climate models from observations or comprehensive high-dimensional climate models is an important topic for atmospheric low-frequency variability, climate sensitivity, and improved extended range forecasting. Here techniques from applied mathematics are utilized to systematically derive normal forms for reduced stochastic climate models for low-frequency variables. The use of a few Empirical Orthogonal Functions (EOFs) (also known as Principal Component Analysis, Karhunen–Loéve and Proper Orthogonal Decomposition) depending on observational data to span the low-frequency subspace requires the assessment of dyad interactions besides the more familiar triads in the interaction between the low- and high-frequency subspaces of the dynamics. It is shown below that the dyad and multiplicative triad interactions combine with the climatological linear operator interactions to simultaneously produce both strong nonlinear dissipation and Correlated Additive and Multiplicative (CAM) stochastic noise. For a single low-frequency variable the dyad interactions and climatological linear operator alone produce a normal form with CAM noise from advection of the large scales by the small scales and simultaneously strong cubic damping. These normal forms should prove useful for developing systematic strategies for the estimation of stochastic models from climate data. As an illustrative example the one-dimensional normal form is applied below to low-frequency patterns such as the North Atlantic Oscillation (NAO) in a climate model. The results here also illustrate the short comings of a recent linear scalar CAM noise model proposed elsewhere for low-frequency variability. PMID:19228943

7 CFR 1942.123 - Loan closing.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 13 2010-01-01 2009-01-01 true Loan closing. 1942.123 Section 1942.123 Agriculture... Loan closing. (a) Ordering loan checks. Checks will not be ordered until: (1) Form FmHA or its... closing instructions, except for those actions which are to be completed on the date of loan closing or...

12 CFR Appendix B to Part 202 - Model Application Forms

Code of Federal Regulations, 2014 CFR

2014-01-01

... 12 Banks and Banking 2 2014-01-01 2014-01-01 false Model Application Forms B Appendix B to Part... CREDIT OPPORTUNITY ACT (REGULATION B) Pt. 202, App. B Appendix B to Part 202—Model Application Forms 1... appear on the creditor's form. 3. If a creditor uses an appropriate Appendix B model form, or modifies a...

A model to determine open or closed cellular convection

NASA Technical Reports Server (NTRS)

Helfand, H. M.; Kalnay, E.

1981-01-01

A simple mechanism is proposed to explain the observed presence in the atmosphere of open or closed cellular convection. If convection is produced by cooling concentrated near the top of the cloud layer, as in radiative cooling of stratus clouds, it develops strong descending currents which are compensated by weak ascent over most of the horizontal area, and closed cells result. Conversely, heating concentrated near the bottom of a layer, as when an air mass is heated by warm water, results in strong ascending currents compensated by weak descent over most of the area, or open cells. This mechanism is similar to the one suggested by Stommel (1962) to explain the smallness of the oceans' sinking regions. The mechanism is studied numerically by means of a two-dimensional, nonlinear Boussinesq model.

Atmosphere behavior in gas-closed mouse-algal systems - An experimental and modelling study

NASA Technical Reports Server (NTRS)

Averner, M. M.; Moore, B., III; Bartholomew, I.; Wharton, R.

1984-01-01

A NASA-sponsored research program initiated using mathematical modelling and laboratory experimentation aimed at examining the gas-exchange characteristics of artificial animal/plant systems closed to the ambient atmosphere is studied. The development of control techniques and management strategies for maintaining the atmospheric levels of carbon dioxide and oxygen at physiological levels is considered. A mathematical model simulating the behavior of a gas-closed mouse-algal system under varying environmental conditions is described. To verify and validate the model simulations, an analytical system with which algal growth and gas exchange characteristics can be manipulated and measured is designed, fabricated, and tested. The preliminary results are presented.

Numerical modelling of closed-cell aluminium foam under dynamic loading

NASA Astrophysics Data System (ADS)

Hazell, Paul; Kader, M. A.; Islam, M. A.; Escobedo, J. P.; Saadatfar, M.

2015-06-01

Closed-cell aluminium foams are extensively used in aerospace and automobile industries. The understanding of their behaviour under impact loading conditions is extremely important since impact problems are directly related to design of these engineering structures. This research investigates the response of a closed-cell aluminium foam (CYMAT) subjected to dynamic loading using the finite element software ABAQUS/explicit. The aim of this research is to numerically investigate the material and structural properties of closed-cell aluminium foam under impact loading conditions with interest in shock propagation and its effects on cell wall deformation. A μ-CT based 3D foam geometry is developed to simulate the local cell collapse behaviours. A number of numerical techniques are applied for modelling the crush behaviour of aluminium foam to obtain the more accurate results. The simulation results are compared with experimental data. Comparison of the results shows a good correlation between the experimental results and numerical predictions.

Development of a Prototype Model-Form Uncertainty Knowledge Base

NASA Technical Reports Server (NTRS)

Green, Lawrence L.

2016-01-01

Uncertainties are generally classified as either aleatory or epistemic. Aleatory uncertainties are those attributed to random variation, either naturally or through manufacturing processes. Epistemic uncertainties are generally attributed to a lack of knowledge. One type of epistemic uncertainty is called model-form uncertainty. The term model-form means that among the choices to be made during a design process within an analysis, there are different forms of the analysis process, which each give different results for the same configuration at the same flight conditions. Examples of model-form uncertainties include the grid density, grid type, and solver type used within a computational fluid dynamics code, or the choice of the number and type of model elements within a structures analysis. The objectives of this work are to identify and quantify a representative set of model-form uncertainties and to make this information available to designers through an interactive knowledge base (KB). The KB can then be used during probabilistic design sessions, so as to enable the possible reduction of uncertainties in the design process through resource investment. An extensive literature search has been conducted to identify and quantify typical model-form uncertainties present within aerospace design. An initial attempt has been made to assemble the results of this literature search into a searchable KB, usable in real time during probabilistic design sessions. A concept of operations and the basic structure of a model-form uncertainty KB are described. Key operations within the KB are illustrated. Current limitations in the KB, and possible workarounds are explained.

Closed loop models for analyzing the effects of simulator characteristics. [digital simulation of human operators

NASA Technical Reports Server (NTRS)

Baron, S.; Muralidharan, R.; Kleinman, D. L.

1978-01-01

The optimal control model of the human operator is used to develop closed loop models for analyzing the effects of (digital) simulator characteristics on predicted performance and/or workload. Two approaches are considered: the first utilizes a continuous approximation to the discrete simulation in conjunction with the standard optimal control model; the second involves a more exact discrete description of the simulator in a closed loop multirate simulation in which the optimal control model simulates the pilot. Both models predict that simulator characteristics can have significant effects on performance and workload.

Simulation of root forms using cellular automata model

NASA Astrophysics Data System (ADS)

Winarno, Nanang; Prima, Eka Cahya; Afifah, Ratih Mega Ayu

2016-02-01

This research aims to produce a simulation program for root forms using cellular automata model. Stephen Wolfram in his book entitled "A New Kind of Science" discusses the formation rules based on the statistical analysis. In accordance with Stephen Wolfram's investigation, the research will develop a basic idea of computer program using Delphi 7 programming language. To best of our knowledge, there is no previous research developing a simulation describing root forms using the cellular automata model compared to the natural root form with the presence of stone addition as the disturbance. The result shows that (1) the simulation used four rules comparing results of the program towards the natural photographs and each rule had shown different root forms; (2) the stone disturbances prevent the root growth and the multiplication of root forms had been successfully modeled. Therefore, this research had added some stones, which have size of 120 cells placed randomly in the soil. Like in nature, stones cannot be penetrated by plant roots. The result showed that it is very likely to further develop the program of simulating root forms by 50 variations.

Simulation of root forms using cellular automata model

DOE Office of Scientific and Technical Information (OSTI.GOV)

Winarno, Nanang, E-mail: nanang-winarno@upi.edu; Prima, Eka Cahya; Afifah, Ratih Mega Ayu

This research aims to produce a simulation program for root forms using cellular automata model. Stephen Wolfram in his book entitled “A New Kind of Science” discusses the formation rules based on the statistical analysis. In accordance with Stephen Wolfram’s investigation, the research will develop a basic idea of computer program using Delphi 7 programming language. To best of our knowledge, there is no previous research developing a simulation describing root forms using the cellular automata model compared to the natural root form with the presence of stone addition as the disturbance. The result shows that (1) the simulation usedmore » four rules comparing results of the program towards the natural photographs and each rule had shown different root forms; (2) the stone disturbances prevent the root growth and the multiplication of root forms had been successfully modeled. Therefore, this research had added some stones, which have size of 120 cells placed randomly in the soil. Like in nature, stones cannot be penetrated by plant roots. The result showed that it is very likely to further develop the program of simulating root forms by 50 variations.« less

31 CFR 50.17 - Use of model forms.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 31 Money and Finance: Treasury 1 2011-07-01 2011-07-01 false Use of model forms. 50.17 Section 50.17 Money and Finance: Treasury Office of the Secretary of the Treasury TERRORISM RISK INSURANCE PROGRAM Disclosures as Conditions for Federal Payment § 50.17 Use of model forms. (a) Policies in force on...

31 CFR 50.17 - Use of model forms.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 31 Money and Finance: Treasury 1 2014-07-01 2014-07-01 false Use of model forms. 50.17 Section 50.17 Money and Finance: Treasury Office of the Secretary of the Treasury TERRORISM RISK INSURANCE PROGRAM Disclosures as Conditions for Federal Payment § 50.17 Use of model forms. (a) Policies in force on...

31 CFR 50.17 - Use of model forms.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 31 Money and Finance: Treasury 1 2012-07-01 2012-07-01 false Use of model forms. 50.17 Section 50.17 Money and Finance: Treasury Office of the Secretary of the Treasury TERRORISM RISK INSURANCE PROGRAM Disclosures as Conditions for Federal Payment § 50.17 Use of model forms. (a) Policies in force on...

31 CFR 50.17 - Use of model forms.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 31 Money and Finance: Treasury 1 2013-07-01 2013-07-01 false Use of model forms. 50.17 Section 50.17 Money and Finance: Treasury Office of the Secretary of the Treasury TERRORISM RISK INSURANCE PROGRAM Disclosures as Conditions for Federal Payment § 50.17 Use of model forms. (a) Policies in force on...

12 CFR Appendix A to Part 704 - Model Forms

Code of Federal Regulations, 2011 CFR

2011-01-01

... 12 Banks and Banking 6 2011-01-01 2011-01-01 false Model Forms A Appendix A to Part 704 Banks and... Pt. 704, App. A Appendix A to Part 704—Model Forms This appendix contains sample forms intended for... corporate credit union. (8) Paid-in capital is perpetual maturity and noncumulative dividend. I have read...

12 CFR Appendix A to Part 704 - Model Forms

Code of Federal Regulations, 2010 CFR

2010-01-01

... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Model Forms A Appendix A to Part 704 Banks and... Pt. 704, App. A Appendix A to Part 704—Model Forms This appendix contains sample forms intended for... corporate credit union. (8) Paid-in capital is perpetual maturity and noncumulative dividend. I have read...

Vacuum effects over the closing of enterocutaneous fistulae: a mathematical modeling approach.

PubMed

Cattoni, D I; Chara, O

2008-01-01

Enterocutaneous fistulae are pathological communications between the intestinal lumen and the abdominal skin. Under surgery the mortality of this pathology is very high, therefore a vacuum applying system has been carried previously on attempting to close these fistulae. The objective of this article is the understanding of how these treatments might work through deterministic mathematical modelling. Four models are here proposed based on several assumptions involving: the conservation of the flow in the fistula, a low enough Reynolds number justifying a laminar flow, the use of Poiseuille law to model the movement of the fistulous liquid, as well as phenomenological equations including the fistula tissue and intermediate chamber compressibility. Interestingly, the four models show fistulae closing behaviour during experimental time (t<60 sec). To compare the models, both, simulations and pressure measurements, carried out on the vacuum connected to the patients, are performed. Time course of pressure are then simulated (from each model) and fitted to the experimental data. The model which best describes actual measurements shows exponential pumping flux kinetics. Applying this model, numerical relationship between the fistula compressibility and closure time is presented. The models here developed would contribute to clarify the treatment mechanism and, eventually, improve the fistulae treatment.

Closed-form expressions for flip angle variation that maximize total signal in T1-weighted rapid gradient echo MRI.

PubMed

Drobnitzky, Matthias; Klose, Uwe

2017-03-01

Magnetization-prepared rapid gradient-echo (MPRAGE) sequences are commonly employed for T1-weighted structural brain imaging. Following a contrast preparation radiofrequency (RF) pulse, the data acquisition proceeds under nonequilibrium conditions of the relaxing longitudinal magnetization. Variation of the flip angle can be used to maximize total available signal. Simulated annealing or greedy algorithms have so far been published to numerically solve this problem, with signal-to-noise ratios optimized for clinical imaging scenarios by adhering to a predefined shape of the signal evolution. We propose an unconstrained optimization of the MPRAGE experiment that employs techniques from resource allocation theory. A new dynamic programming solution is introduced that yields closed-form expressions for optimal flip angle variation. Flip angle series are proposed that maximize total transverse magnetization (Mxy) for a range of physiologic T1 values. A 3D MPRAGE sequence is modified to allow for a controlled variation of the excitation angle. Experiments employing a T1 contrast phantom are performed at 3T. 1D acquisitions without phase encoding permit measurement of the temporal development of Mxy. Image mean signal and standard deviation for reference flip angle trains are compared in 2D measurements. Signal profiles at sharp phantom edges are acquired to access image blurring related to nonuniform Mxy development. A novel closed-form expression for flip angle variation is found that constitutes the optimal policy to reach maximum total signal. It numerically equals previously published results of other authors when evaluated under their simplifying assumptions. Longitudinal magnetization (Mz) is exhaustively used without causing abrupt changes in the measured MR signal, which is a prerequisite for artifact free images. Phantom experiments at 3T verify the expected benefit for total accumulated k-space signal when compared with published flip angle series. Describing

Noncommutative-geometry model for closed bosonic strings

NASA Technical Reports Server (NTRS)

Sen, Siddhartha; Holman, R.

1987-01-01

It is shown how Witten's (1986) noncommutative geometry may be extended to describe the closed bosonic string. For closed strings, an explicit representation is provided of the integral operator needed to construct an action and of an associative product on string fields. The proper choice of the action of the integral operator and the associative product in order to give rise to a reasonable theory is explained, and the consequences of such a choice are discussed. It is shown that the ghost numbers of the operator and associative product can be chosen arbitrarily for both open and closed strings, and that this construct can be used as an action for interacting closed bosonic strings.

Closed Form Solutions for Unsteady Free Convection Flow of a Second Grade Fluid over an Oscillating Vertical Plate

PubMed Central

Ali, Farhad; Khan, Ilyas; Shafie, Sharidan

2014-01-01

Closed form solutions for unsteady free convection flows of a second grade fluid near an isothermal vertical plate oscillating in its plane using the Laplace transform technique are established. Expressions for velocity and temperature are obtained and displayed graphically for different values of Prandtl number Pr, thermal Grashof number Gr, viscoelastic parameter α, phase angle ωτ and time τ. Numerical values of skin friction τ 0 and Nusselt number Nu are shown in tables. Some well-known solutions in literature are reduced as the limiting cases of the present solutions. PMID:24551033

Closed-loop supply chain models with considering the environmental impact.

PubMed

Mohajeri, Amir; Fallah, Mohammad

2014-01-01

Global warming and climate changes created by large scale emissions of greenhouse gases are a worldwide concern. Due to this, the issue of green supply chain management has received more attention in the last decade. In this study, a closed-loop logistic concept which serves the purposes of recycling, reuse, and recovery required in a green supply chain is applied to integrate the environmental issues into a traditional logistic system. Here, we formulate a comprehensive closed-loop model for the logistics planning considering profitability and ecological goals. In this way, we can achieve the ecological goal reducing the overall amount of CO2 emitted from journeys. Moreover, the profitability criterion can be supported in the cyclic network with the minimum costs and maximum service level. We apply three scenarios and develop problem formulations for each scenario corresponding to the specified regulations and investigate the effect of the regulation on the preferred transport mode and the emissions. To validate the models, some numerical experiments are worked out and a comparative analysis is investigated.

Closed-Loop Supply Chain Models with Considering the Environmental Impact

PubMed Central

Fallah, Mohammad

2014-01-01

Global warming and climate changes created by large scale emissions of greenhouse gases are a worldwide concern. Due to this, the issue of green supply chain management has received more attention in the last decade. In this study, a closed-loop logistic concept which serves the purposes of recycling, reuse, and recovery required in a green supply chain is applied to integrate the environmental issues into a traditional logistic system. Here, we formulate a comprehensive closed-loop model for the logistics planning considering profitability and ecological goals. In this way, we can achieve the ecological goal reducing the overall amount of CO2 emitted from journeys. Moreover, the profitability criterion can be supported in the cyclic network with the minimum costs and maximum service level. We apply three scenarios and develop problem formulations for each scenario corresponding to the specified regulations and investigate the effect of the regulation on the preferred transport mode and the emissions. To validate the models, some numerical experiments are worked out and a comparative analysis is investigated. PMID:25309960

12 CFR Appendix A to Part 213 - Model Forms

Code of Federal Regulations, 2010 CFR

2010-01-01

... 12 Banks and Banking 2 2010-01-01 2010-01-01 false Model Forms A Appendix A to Part 213 Banks and Banking FEDERAL RESERVE SYSTEM BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM CONSUMER LEASING (REGULATION M) Pt. 213, App. A Appendix A to Part 213—Model Forms A-1Model Open-End or Finance Vehicle Lease...

12 CFR Appendix A to Part 213 - Model Forms

Code of Federal Regulations, 2011 CFR

2011-01-01

... 12 Banks and Banking 2 2011-01-01 2011-01-01 false Model Forms A Appendix A to Part 213 Banks and Banking FEDERAL RESERVE SYSTEM BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM CONSUMER LEASING (REGULATION M) Pt. 213, App. A Appendix A to Part 213—Model Forms A-1Model Open-End or Finance Vehicle Lease...

Close-form expression of one-tap normalized LMS carrier phase recovery in optical communication systems

NASA Astrophysics Data System (ADS)

Xu, Tianhua; Jacobsen, Gunnar; Popov, Sergei; Li, Jie; Liu, Tiegen; Zhang, Yimo

2016-10-01

The performance of long-haul high speed coherent optical fiber communication systems is significantly degraded by the laser phase noise and the equalization enhanced phase noise (EEPN). In this paper, the analysis of the one-tap normalized least-mean-square (LMS) carrier phase recovery (CPR) is carried out and the close-form expression is investigated for quadrature phase shift keying (QPSK) coherent optical fiber communication systems, in compensating both laser phase noise and equalization enhanced phase noise. Numerical simulations have also been implemented to verify the theoretical analysis. It is found that the one-tap normalized least-mean-square algorithm gives the same analytical expression for predicting CPR bit-error-rate (BER) floors as the traditional differential carrier phase recovery, when both the laser phase noise and the equalization enhanced phase noise are taken into account.

A mechanistic model for the prediction of in-use moisture uptake by packaged dosage forms.

PubMed

Remmelgas, Johan; Simonutti, Anne-Laure; Ronkvist, Asa; Gradinarsky, Lubomir; Löfgren, Anders

2013-01-30

A mechanistic model for the prediction of in-use moisture uptake of solid dosage forms in bottles is developed. The model considers moisture transport into the bottle and moisture uptake by the dosage form both when the bottle is closed and when it is open. Experiments are carried out by placing tablets and desiccant canisters in bottles and monitoring their moisture content. Each bottle is opened once a day to remove one tablet or desiccant canister. Opening the bottle to remove a tablet or canister also causes some exchange of air between the bottle headspace and the environment. In order to ascertain how this air exchange might depend on the customer, tablets and desiccant canisters are removed from the bottles by either carefully removing only one or by pouring all of the tablets or desiccant canisters out of the bottle, removing one, and pouring the remaining ones back into the bottle. The predictions of the model are found to be in good agreement with experimental data for moisture sorption by desiccant canisters. Moreover, it is found experimentally that the manner in which the tablets or desiccant canisters were removed does not appreciably affect their moisture content. Copyright © 2012 Elsevier B.V. All rights reserved.

Dependence of cell adhesion on extracellular matrix materials formed on pore bridge boundaries by nanopore opening and closing geometry.

PubMed

Kim, Sueon; Han, Dong Yeol; Chen, Zhenzhong; Lee, Won Gu

2018-04-30

In this study, we report experimental results for characterization of the growth and formation of pore bridge materials that modified the adhesion structures of cells cultured on nanomembranes with opening and closing geometry. To perform the proof-of-concept experiments, we fabricated two types of anodized alumina oxide substrates with single-sided opening (i.e., one side open, but closed at the other side) and double-sided opening (i.e., both sides open). In our experiment, we compared the densities of pores formed and of bridge materials which differently act as connective proteins depending on the size of pores. The results show that the pore opening geometry can be used to promote the net contact force between pores, resulting in the growth and formation of pore bridge materials before and after cell culture. The results also imply that the bridge materials can be used to attract the structural protrusion of filopodia that can promote the adhesion of cell-to-cell and cell-to-pore bridge. It is observed that the shape and size of cellular structures of filopodia depend on the presence of pore bridge materials. Overall, this observation brought us a significant clue that cells cultured on nanopore substrates would change the adhesion property depending on not only the formation of nanopores formed on the surface of topological substrates, but also that of pore bridge materials by its morphological growth.

Why Do Some Estuaries Close: A Model of Estuary Entrance Morphodynamics.

NASA Astrophysics Data System (ADS)

McSweeney, S. L.; Kennedy, D. M.; Rutherfurd, I.

2014-12-01

Intermittently Closed/Open Coastal Lakes/Lagoons (ICOLLs) are a form of wave-dominated, microtidal estuary that experience periodic closure in times of low river flow. ICOLL entrance morphodynamics are complex due to the interaction between wave, tidal and fluvial processes. Managers invest substantial funds to artificially open ICOLLs as they flood surrounding property and infrastructure, and have poor water quality. Existing studies examine broad scale processes but do not identify the main drivers of entrance condition. In this research, the changes in entrance geomorphology were surveyed before and after artificial entrance openings in three ICOLLs in Victoria, Australia. Changes in morphology were related to continuous measures of sediment volume, water level, tide and wave energy. A six-stage quantitative phase model of entrance geomorphology and hydrodynamics is presented to illustrate the spatio-temporal variability in ICOLL entrance morphodynamics. Phases include: breakout; channel expansion with rapid outflow; open with tidal exchange; initial berm rebuilding with tidal attenuation; partial berm recovery with rising water levels; closed with perched water levels. Entrance breakout initiates incision of a pilot channel to the ocean, whereby basin water levels then decline and channel expansion as the headcut migrates landwards. Peak outflow velocities of 5 m/s-3 were recorded and channel dimensions increased over 6 hrs to 3.5 m deep and 140 m wide. When tidal, a clear semi-diurnal signal is superimposed upon an otherwise stable water level. Deep-water wave energy was transferred 1.8 km upstream of the rivermouth with bores present in the basin. Berm rebuilding occurred by littoral drift and cross-shore transport once outflow ceased and microscale bedform features, particularly antidunes, contributed to sediment progradation. Phase duration is dependant on how high the estuary was perched above mean sea level, tidal prism extent, and onshore sediment supply

A Novel Closed-Head Model of Mild Traumatic Brain Injury Using Focal Primary Overpressure Blast to the Cranium in Mice

PubMed Central

Guley, Natalie H.; Rogers, Joshua T.; Del Mar, Nobel A.; Deng, Yunping; Islam, Rafiqul M.; D'Surney, Lauren; Ferrell, Jessica; Deng, Bowei; Hines-Beard, Jessica; Bu, Wei; Ren, Huiling; Elberger, Andrea J.; Marchetta, Jeffrey G.; Rex, Tonia S.; Honig, Marcia G.

2016-01-01

Abstract Mild traumatic brain injury (TBI) from focal head impact is the most common form of TBI in humans. Animal models, however, typically use direct impact to the exposed dura or skull, or blast to the entire head. We present a detailed characterization of a novel overpressure blast system to create focal closed-head mild TBI in mice. A high-pressure air pulse limited to a 7.5 mm diameter area on the left side of the head overlying the forebrain is delivered to anesthetized mice. The mouse eyes and ears are shielded, and its head and body are cushioned to minimize movement. This approach creates mild TBI by a pressure wave that acts on the brain, with minimal accompanying head acceleration-deceleration. A single 20-psi blast yields no functional deficits or brain injury, while a single 25–40 psi blast yields only slight motor deficits and brain damage. By contrast, a single 50–60 psi blast produces significant visual, motor, and neuropsychiatric impairments and axonal damage and microglial activation in major fiber tracts, but no contusive brain injury. This model thus reproduces the widespread axonal injury and functional impairments characteristic of closed-head mild TBI, without the complications of systemic or ocular blast effects or head acceleration that typically occur in other blast or impact models of closed-skull mild TBI. Accordingly, our model provides a simple way to examine the biomechanics, pathophysiology, and functional deficits that result from TBI and can serve as a reliable platform for testing therapies that reduce brain pathology and deficits. PMID:26414413

Functional form diagnostics for Cox's proportional hazards model.

PubMed

León, Larry F; Tsai, Chih-Ling

2004-03-01

We propose a new type of residual and an easily computed functional form test for the Cox proportional hazards model. The proposed test is a modification of the omnibus test for testing the overall fit of a parametric regression model, developed by Stute, González Manteiga, and Presedo Quindimil (1998, Journal of the American Statistical Association93, 141-149), and is based on what we call censoring consistent residuals. In addition, we develop residual plots that can be used to identify the correct functional forms of covariates. We compare our test with the functional form test of Lin, Wei, and Ying (1993, Biometrika80, 557-572) in a simulation study. The practical application of the proposed residuals and functional form test is illustrated using both a simulated data set and a real data set.

SC-GRAPPA: Self-constraint noniterative GRAPPA reconstruction with closed-form solution.

PubMed

Ding, Yu; Xue, Hui; Ahmad, Rizwan; Ting, Samuel T; Simonetti, Orlando P

2012-12-01

Parallel MRI (pMRI) reconstruction techniques are commonly used to reduce scan time by undersampling the k-space data. GRAPPA, a k-space based pMRI technique, is widely used clinically because of its robustness. In GRAPPA, the missing k-space data are estimated by solving a set of linear equations; however, this set of equations does not take advantage of the correlations within the missing k-space data. All k-space data in a neighborhood acquired from a phased-array coil are correlated. The correlation can be estimated easily as a self-constraint condition, and formulated as an extra set of linear equations to improve the performance of GRAPPA. The authors propose a modified k-space based pMRI technique called self-constraint GRAPPA (SC-GRAPPA) which combines the linear equations of GRAPPA with these extra equations to solve for the missing k-space data. Since SC-GRAPPA utilizes a least-squares solution of the linear equations, it has a closed-form solution that does not require an iterative solver. The SC-GRAPPA equation was derived by incorporating GRAPPA as a prior estimate. SC-GRAPPA was tested in a uniform phantom and two normal volunteers. MR real-time cardiac cine images with acceleration rate 5 and 6 were reconstructed using GRAPPA and SC-GRAPPA. SC-GRAPPA showed a significantly lower artifact level, and a greater than 10% overall signal-to-noise ratio (SNR) gain over GRAPPA, with more significant SNR gain observed in low-SNR regions of the images. SC-GRAPPA offers improved pMRI reconstruction, and is expected to benefit clinical imaging applications in the future.

Topology Model of the Flow around a Submarine Hull Form

DTIC Science & Technology

2015-12-01

UNCLASSIFIED Topology Model of the Flow around a Submarine Hull Form S.-K. Lee Maritime Division Defence Science and Technology Group DST-Group–TR...3177 ABSTRACT A topology model constructed from surface-streamer visualisation describes the flow around a generic conventional submarine hull form at...pure yaw angles of 0 ◦, 10 ◦ and 18 ◦. The model is used to develop equations for sway-force and yaw-moment coefficients which relate to the hull - form

7 CFR 1927.54 - Requirements for closing agents.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 12 2010-01-01 2010-01-01 false Requirements for closing agents. 1927.54 Section 1927... PROGRAM REGULATIONS TITLE CLEARANCE AND LOAN CLOSING Real Estate Title Clearance and Loan Closing § 1927.54 Requirements for closing agents. (a) Form of title certification. State Offices are directed to...

Closed-form solutions of the Wheeler-DeWitt equation in a scalar-vector field cosmological model by Lie symmetries

NASA Astrophysics Data System (ADS)

Paliathanasis, Andronikos; Vakili, Babak

2016-01-01

We apply as selection rule to determine the unknown functions of a cosmological model the existence of Lie point symmetries for the Wheeler-DeWitt equation of quantum gravity. Our cosmological setting consists of a flat Friedmann-Robertson-Walker metric having the scale factor a( t), a scalar field with potential function V(φ ) minimally coupled to gravity and a vector field of its kinetic energy is coupled with the scalar field by a coupling function f(φ ). Then, the Lie symmetries of this dynamical system are investigated by utilizing the behavior of the corresponding minisuperspace under the infinitesimal generator of the desired symmetries. It is shown that by applying the Lie symmetry condition the form of the coupling function and also the scalar field potential function may be explicitly determined so that we are able to solve the Wheeler-DeWitt equation. Finally, we show how we can use the Lie symmetries in order to construct conservation laws and exact solutions for the field equations.

Analytical close-form solutions to the elastic fields of solids with dislocations and surface stress

NASA Astrophysics Data System (ADS)

Ye, Wei; Paliwal, Bhasker; Ougazzaden, Abdallah; Cherkaoui, Mohammed

2013-07-01

The concept of eigenstrain is adopted to derive a general analytical framework to solve the elastic field for 3D anisotropic solids with general defects by considering the surface stress. The formulation shows the elastic constants and geometrical features of the surface play an important role in determining the elastic fields of the solid. As an application, the analytical close-form solutions to the stress fields of an infinite isotropic circular nanowire are obtained. The stress fields are compared with the classical solutions and those of complex variable method. The stress fields from this work demonstrate the impact from the surface stress when the size of the nanowire shrinks but becomes negligible in macroscopic scale. Compared with the power series solutions of complex variable method, the analytical solutions in this work provide a better platform and they are more flexible in various applications. More importantly, the proposed analytical framework profoundly improves the studies of general 3D anisotropic materials with surface effects.

A Study on Ganui-Dae's External Form and Its Modeling for Ganui-Dae's External Form and Its Modeling for Restoration

NASA Astrophysics Data System (ADS)

Lee, Min-Soo; Lee, Yong Sam; Jeon, Jun Hyeok; Kim, Sang Hyuk

2013-12-01

Ganui-Dae, built in the reign of King Sejong, Joseon Dynasty, is a comprehensive observatory. It has various instruments for observation and time signal such as Ganui, Gyupyo(Gnomon), water-hammering type Honui and Honsang, and so on. Studying on Ganui-Dae has been focused on its location, history, criterion, etc, so far. However, studying on its external form and construction method has been conducted insufficiently. This study suggests the model for restoration of Ganui-Dae. The model is based on the analysis about external form of Ganui-Dae in various antique maps, and its construction method in those days.

Abundant closed form solutions of the conformable time fractional Sawada-Kotera-Ito equation using (G‧ / G) -expansion method

NASA Astrophysics Data System (ADS)

Al-Shawba, Altaf Abdulkarem; Gepreel, K. A.; Abdullah, F. A.; Azmi, A.

2018-06-01

In current study, we use the (G‧ / G) -expansion method to construct the closed form solutions of the seventh order time fractional Sawada-Kotera-Ito (TFSKI) equation based on conformable fractional derivative. As a result, trigonometric, hyperbolic and rational functions solutions with arbitrary constants are obtained. When the arbitrary constants are taken some special values, the periodic and soliton solutions are obtained from the travelling wave solutions. The obtained solutions are new and not found elsewhere. The effect of the fractional order on some of these solutions are represented graphically to illustrate the behavior of the exact solutions when the parameter take some special choose.

New developments in tribomechanical modeling of automotive sheet steel forming

NASA Astrophysics Data System (ADS)

Khandeparkar, Tushar; Chezan, Toni; van Beeck, Jeroen

2018-05-01

Forming of automotive sheet metal body panels is a complex process influenced by both the material properties and contact conditions in the forming tooling. Material properties are described by the material constitutive behavior and the material flow into the forming die can be described by the tribological system. This paper investigates the prediction accuracy of the forming process using the Tata Steel state of the art description of the material constitutive behavior in combination with different friction models. A cross-die experiment is used to investigate the accuracy of local deformation modes typically seen in automotive sheet metal forming operations. Results of advanced friction models as well as the classical Coulomb friction description are compared to the experimentally measured strain distribution and material draw-in. Two hot-dip galvanized coated steel forming grades were used for the investigations. The results show that the accuracy of the simulation is not guaranteed by the advanced friction models for the entire investigated blank holder force range, both globally and locally. A measurable difference between the calculated and measured local strains is seen for both studied models even in the case where the global indicator, i.e. the draw-in, is well predicted.

Modeling close encounters with massive asteroids: a Markovian approach. An application to the Vesta family

NASA Astrophysics Data System (ADS)

Carruba, V.; Roig, F.; Michtchenko, T. A.; Ferraz-Mello, S.; Nesvorný, D.

2007-04-01

Context: Nearly all members of the Vesta family cross the orbits of (4) Vesta, one of the most massive asteroids in the main belt, and some of them approach it closely. When mutual velocities during such close encounters are low, the trajectory of the small body can be gravitationally deflected, consequently changing its heliocentric orbital elements. While the effect of a single close encounter may be small, repeated close encounters may significantly change the proper element distribution of members of asteroid families. Aims: We develop a model of the long-term effect of close encounters with massive asteroids, so as to be able to predict how far former members of the Vesta family could have drifted away from the family. Methods: We first developed a new symplectic integrator that simulates both the effects of close encounters and the Yarkovsky effect. We analyzed the results of a simulation involving a fictitious Vesta family, and propagated the asteroid proper element distribution using the probability density function (pdf hereafter), i.e. the function that describes the probability of having an encounter that modifies a proper element x by Δx, for all the possible values of Δx. Given any asteroids' proper element distribution at time t, the distribution at time t+T may be predicted if the pdf is known (Bachelier 1900, Théorie de la spéculation; Hughes 1995, Random Walks and Random Environments, Vol. I). Results: We applied our new method to the problem of V-type asteroids outside the Vesta family (i.e., the 31 currently known asteroids in the inner asteroid belt that have the same spectral type of members as the Vesta family, but that are outside the limits of the dynamical family) and determined that at least ten objects have a significant diffusion probability over the minimum estimated age of the Vesta family of 1.2 Gyr (Carruba et al. 2005, A&A, 441, 819). These objects can therefore be explained in the framework of diffusion via repeated close

The fundamental closed-form solution of control-related states of kth order S3PR system with left-side non-sharing resource places of Petri nets

NASA Astrophysics Data System (ADS)

Chao, Daniel Yuh; Yu, Tsung Hsien

2016-01-01

Due to the state explosion problem, it has been unimaginable to enumerate reachable states for Petri nets. Chao broke the barrier earlier by developing the very first closed-form solution of the number of reachable and other states for marked graphs and the kth order system. Instead of using first-met bad marking, we propose 'the moment to launch resource allocation' (MLR) as a partial deadlock avoidance policy for a large, real-time dynamic resource allocation system. Presently, we can use the future deadlock ratio of the current state as the indicator of MLR due to which the ratio can be obtained real-time by a closed-form formula. This paper progresses the application of an MLR concept one step further on Gen-Left kth order systems (one non-sharing resource place in any position of the left-side process), which is also the most fundamental asymmetric net structure, by the construction of the system's closed-form solution of the control-related states (reachable, forbidden, live and deadlock states) with a formula depending on the parameters of k and the location of the non-sharing resource. Here, we kick off a new era of real-time, dynamic resource allocation decisions by constructing a generalisation formula of kth order systems (Gen-Left) with r* on the left side but at arbitrary locations.

A LabVIEW model incorporating an open-loop arterial impedance and a closed-loop circulatory system.

PubMed

Cole, R T; Lucas, C L; Cascio, W E; Johnson, T A

2005-11-01

While numerous computer models exist for the circulatory system, many are limited in scope, contain unwanted features or incorporate complex components specific to unique experimental situations. Our purpose was to develop a basic, yet multifaceted, computer model of the left heart and systemic circulation in LabVIEW having universal appeal without sacrificing crucial physiologic features. The program we developed employs Windkessel-type impedance models in several open-loop configurations and a closed-loop model coupling a lumped impedance and ventricular pressure source. The open-loop impedance models demonstrate afterload effects on arbitrary aortic pressure/flow inputs. The closed-loop model catalogs the major circulatory waveforms with changes in afterload, preload, and left heart properties. Our model provides an avenue for expanding the use of the ventricular equations through closed-loop coupling that includes a basic coronary circuit. Tested values used for the afterload components and the effects of afterload parameter changes on various waveforms are consistent with published data. We conclude that this model offers the ability to alter several circulatory factors and digitally catalog the most salient features of the pressure/flow waveforms employing a user-friendly platform. These features make the model a useful instructional tool for students as well as a simple experimental tool for cardiovascular research.

Building Facade Modeling Under Line Feature Constraint Based on Close-Range Images

NASA Astrophysics Data System (ADS)

Liang, Y.; Sheng, Y. H.

2018-04-01

To solve existing problems in modeling facade of building merely with point feature based on close-range images , a new method for modeling building facade under line feature constraint is proposed in this paper. Firstly, Camera parameters and sparse spatial point clouds data were restored using the SFM , and 3D dense point clouds were generated with MVS; Secondly, the line features were detected based on the gradient direction , those detected line features were fit considering directions and lengths , then line features were matched under multiple types of constraints and extracted from multi-image sequence. At last, final facade mesh of a building was triangulated with point cloud and line features. The experiment shows that this method can effectively reconstruct the geometric facade of buildings using the advantages of combining point and line features of the close - range image sequence, especially in restoring the contour information of the facade of buildings.

Feasibility of Close-Range Photogrammetric Models for Geographic Information System

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhou, Luke; /Rice U.

2011-06-22

The objective of this project was to determine the feasibility of using close-range architectural photogrammetry as an alternative three dimensional modeling technique in order to place the digital models in a geographic information system (GIS) at SLAC. With the available equipment and Australis photogrammetry software, the creation of full and accurate models of an example building, Building 281 on SLAC campus, was attempted. After conducting several equipment tests to determine the precision achievable, a complete photogrammetric survey was attempted. The dimensions of the resulting models were then compared against the true dimensions of the building. A complete building model wasmore » not evidenced to be obtainable using the current equipment and software. This failure was likely attributable to the limits of the software rather than the precision of the physical equipment. However, partial models of the building were shown to be accurate and determined to still be usable in a GIS. With further development of the photogrammetric software and survey procedure, the desired generation of a complete three dimensional model is likely still feasible.« less

Application of closed-form solutions to a mesh point field in silicon solar cells

NASA Technical Reports Server (NTRS)

Lamorte, M. F.

1985-01-01

A computer simulation method is discussed that provides for equivalent simulation accuracy, but that exhibits significantly lower CPU running time per bias point compared to other techniques. This new method is applied to a mesh point field as is customary in numerical integration (NI) techniques. The assumption of a linear approximation for the dependent variable, which is typically used in the finite difference and finite element NI methods, is not required. Instead, the set of device transport equations is applied to, and the closed-form solutions obtained for, each mesh point. The mesh point field is generated so that the coefficients in the set of transport equations exhibit small changes between adjacent mesh points. Application of this method to high-efficiency silicon solar cells is described; and the method by which Auger recombination, ambipolar considerations, built-in and induced electric fields, bandgap narrowing, carrier confinement, and carrier diffusivities are treated. Bandgap narrowing has been investigated using Fermi-Dirac statistics, and these results show that bandgap narrowing is more pronounced and that it is temperature-dependent in contrast to the results based on Boltzmann statistics.

Cycle-averaged dynamics of a periodically driven, closed-loop circulation model

NASA Technical Reports Server (NTRS)

Heldt, T.; Chang, J. L.; Chen, J. J. S.; Verghese, G. C.; Mark, R. G.

2005-01-01

Time-varying elastance models have been used extensively in the past to simulate the pulsatile nature of cardiovascular waveforms. Frequently, however, one is interested in dynamics that occur over longer time scales, in which case a detailed simulation of each cardiac contraction becomes computationally burdensome. In this paper, we apply circuit-averaging techniques to a periodically driven, closed-loop, three-compartment recirculation model. The resultant cycle-averaged model is linear and time invariant, and greatly reduces the computational burden. It is also amenable to systematic order reduction methods that lead to further efficiencies. Despite its simplicity, the averaged model captures the dynamics relevant to the representation of a range of cardiovascular reflex mechanisms. c2004 Elsevier Ltd. All rights reserved.

Integrating Entropy and Closed Frequent Pattern Mining for Social Network Modelling and Analysis

NASA Astrophysics Data System (ADS)

Adnan, Muhaimenul; Alhajj, Reda; Rokne, Jon

The recent increase in the explicitly available social networks has attracted the attention of the research community to investigate how it would be possible to benefit from such a powerful model in producing effective solutions for problems in other domains where the social network is implicit; we argue that social networks do exist around us but the key issue is how to realize and analyze them. This chapter presents a novel approach for constructing a social network model by an integrated framework that first preparing the data to be analyzed and then applies entropy and frequent closed patterns mining for network construction. For a given problem, we first prepare the data by identifying items and transactions, which arc the basic ingredients for frequent closed patterns mining. Items arc main objects in the problem and a transaction is a set of items that could exist together at one time (e.g., items purchased in one visit to the supermarket). Transactions could be analyzed to discover frequent closed patterns using any of the well-known techniques. Frequent closed patterns have the advantage that they successfully grab the inherent information content of the dataset and is applicable to a broader set of domains. Entropies of the frequent closed patterns arc used to keep the dimensionality of the feature vectors to a reasonable size; it is a kind of feature reduction process. Finally, we analyze the dynamic behavior of the constructed social network. Experiments were conducted on a synthetic dataset and on the Enron corpus email dataset. The results presented in the chapter show that social networks extracted from a feature set as frequent closed patterns successfully carry the community structure information. Moreover, for the Enron email dataset, we present an analysis to dynamically indicate the deviations from each user's individual and community profile. These indications of deviations can be very useful to identify unusual events.

Globally optimal grouping for symmetric closed boundaries by combining boundary and region information.

PubMed

Stahl, Joachim S; Wang, Song

2008-03-01

Many natural and man-made structures have a boundary that shows a certain level of bilateral symmetry, a property that plays an important role in both human and computer vision. In this paper, we present a new grouping method for detecting closed boundaries with symmetry. We first construct a new type of grouping token in the form of symmetric trapezoids by pairing line segments detected from the image. A closed boundary can then be achieved by connecting some trapezoids with a sequence of gap-filling quadrilaterals. For such a closed boundary, we define a unified grouping cost function in a ratio form: the numerator reflects the boundary information of proximity and symmetry and the denominator reflects the region information of the enclosed area. The introduction of the region-area information in the denominator is able to avoid a bias toward shorter boundaries. We then develop a new graph model to represent the grouping tokens. In this new graph model, the grouping cost function can be encoded by carefully designed edge weights and the desired optimal boundary corresponds to a special cycle with a minimum ratio-form cost. We finally show that such a cycle can be found in polynomial time using a previous graph algorithm. We implement this symmetry-grouping method and test it on a set of synthetic data and real images. The performance is compared to two previous grouping methods that do not consider symmetry in their grouping cost functions.

Open and partially closed models of the solar wind interaction with outer planet magnetospheres: the case of Saturn

NASA Astrophysics Data System (ADS)

Belenkaya, Elena S.; Cowley, Stanley W. H.; Alexeev, Igor I.; Kalegaev, Vladimir V.; Pensionerov, Ivan A.; Blokhina, Marina S.; Parunakian, David A.

2017-12-01

A wide variety of interactions take place between the magnetized solar wind plasma outflow from the Sun and celestial bodies within the solar system. Magnetized planets form magnetospheres in the solar wind, with the planetary field creating an obstacle in the flow. The reconnection efficiency of the solar-wind-magnetized planet interaction depends on the conditions in the magnetized plasma flow passing the planet. When the reconnection efficiency is very low, the interplanetary magnetic field (IMF) does not penetrate the magnetosphere, a condition that has been widely discussed in the recent literature for the case of Saturn. In the present paper, we study this issue for Saturn using Cassini magnetometer data, images of Saturn's ultraviolet aurora obtained by the HST, and the paraboloid model of Saturn's magnetospheric magnetic field. Two models are considered: first, an open model in which the IMF penetrates the magnetosphere, and second, a partially closed model in which field lines from the ionosphere go to the distant tail and interact with the solar wind at its end. We conclude that the open model is preferable, which is more obvious for southward IMF. For northward IMF, the model calculations do not allow us to reach definite conclusions. However, analysis of the observations available in the literature provides evidence in favor of the open model in this case too. The difference in magnetospheric structure for these two IMF orientations is due to the fact that the reconnection topology and location depend on the relative orientation of the IMF vector and the planetary dipole magnetic moment. When these vectors are parallel, two-dimensional reconnection occurs at the low-latitude neutral line. When they are antiparallel, three-dimensional reconnection takes place in the cusp regions. Different magnetospheric topologies determine different mapping of the open-closed boundary in the ionosphere, which can be considered as a proxy for the poleward edge of the

A hydrophobic gate in an ion channel: the closed state of the nicotinic acetylcholine receptor

NASA Astrophysics Data System (ADS)

Beckstein, Oliver; Sansom, Mark S. P.

2006-06-01

The nicotinic acetylcholine receptor (nAChR) is the prototypic member of the 'Cys-loop' superfamily of ligand-gated ion channels which mediate synaptic neurotransmission, and whose other members include receptors for glycine, γ-aminobutyric acid and serotonin. Cryo-electron microscopy has yielded a three-dimensional structure of the nAChR in its closed state. However, the exact nature and location of the channel gate remains uncertain. Although the transmembrane pore is constricted close to its center, it is not completely occluded. Rather, the pore has a central hydrophobic zone of radius about 3 Å. Model calculations suggest that such a constriction may form a hydrophobic gate, preventing movement of ions through a channel. We present a detailed and quantitative simulation study of the hydrophobic gating model of the nicotinic receptor, in order to fully evaluate this hypothesis. We demonstrate that the hydrophobic constriction of the nAChR pore indeed forms a closed gate. Potential of mean force (PMF) calculations reveal that the constriction presents a barrier of height about 10 kT to the permeation of sodium ions, placing an upper bound on the closed channel conductance of 0.3 pS. Thus, a 3 Å radius hydrophobic pore can form a functional barrier to the permeation of a 1 Å radius Na+ ion. Using a united-atom force field for the protein instead of an all-atom one retains the qualitative features but results in differing conductances, showing that the PMF is sensitive to the detailed molecular interactions.

Existence of standard models of conic fibrations over non-algebraically-closed fields

DOE Office of Scientific and Technical Information (OSTI.GOV)

Avilov, A A

2014-12-31

We prove an analogue of Sarkisov's theorem on the existence of a standard model of a conic fibration over an algebraically closed field of characteristic different from two for three-dimensional conic fibrations over an arbitrary field of characteristic zero with an action of a finite group. Bibliography: 16 titles.

Epistemic companions: shared reality development in close relationships.

PubMed

Rossignac-Milon, Maya; Higgins, E Tory

2018-01-11

We propose a framework outlining the development of shared reality in close relationships. In this framework, we attempt to integrate disparate close relationship phenomena under the conceptual umbrella of shared reality. We argue that jointly satisfying epistemic needs-making sense of the world together-plays an important but under-appreciated role in establishing and maintaining close relationships. Specifically, we propose that dyads progress through four cumulative phases in which new forms of shared reality emerge. Relationships are often initiated when people discover Shared Feelings, which then facilitate the co-construction of dyad-specific Shared Practices. Partners then form an interdependent web of Shared Coordination and ultimately develop a Shared Identity. Each emergent form of shared reality continues to evolve throughout subsequent phases, and, if neglected, can engender relationship dissolution. Copyright © 2018 Elsevier Ltd. All rights reserved.

A power-law coupled three-form dark energy model

NASA Astrophysics Data System (ADS)

Yao, Yan-Hong; Yan, Yang-Jie; Meng, Xin-He

2018-02-01

We consider a field theory model of coupled dark energy which treats dark energy as a three-form field and dark matter as a spinor field. By assuming the effective mass of dark matter as a power-law function of the three-form field and neglecting the potential term of dark energy, we obtain three solutions of the autonomous system of evolution equations, including a de Sitter attractor, a tracking solution and an approximate solution. To understand the strength of the coupling, we confront the model with the latest Type Ia Supernova, Baryon Acoustic Oscillations and Cosmic Microwave Background radiation observations, with the conclusion that the combination of these three databases marginalized over the present dark matter density parameter Ω _{m0} and the present three-form field κ X0 gives stringent constraints on the coupling constant, - 0.017< λ <0.047 (2σ confidence level), by which we present the model's applicable parameter range.

New closed-form approximation for skin chromophore mapping.

PubMed

Välisuo, Petri; Kaartinen, Ilkka; Tuchin, Valery; Alander, Jarmo

2011-04-01

The concentrations of blood and melanin in skin can be estimated based on the reflectance of light. Many models for this estimation have been built, such as Monte Carlo simulation, diffusion models, and the differential modified Beer-Lambert law. The optimization-based methods are too slow for chromophore mapping of high-resolution spectral images, and the differential modified Beer-Lambert is not often accurate enough. Optimal coefficients for the differential Beer-Lambert model are calculated by differentiating the diffusion model, optimized to the normal skin spectrum. The derivatives are then used in predicting the difference in chromophore concentrations from the difference in absorption spectra. The accuracy of the method is tested both computationally and experimentally using a Monte Carlo multilayer simulation model, and the data are measured from the palm of a hand during an Allen's test, which modulates the blood content of skin. The correlations of the given and predicted blood, melanin, and oxygen saturation levels are correspondingly r = 0.94, r = 0.99, and r = 0.73. The prediction of the concentrations for all pixels in a 1-megapixel image would take ∼ 20 min, which is orders of magnitude faster than the methods based on optimization during the prediction.

Modeling and closed-loop control of hypnosis by means of bispectral index (BIS) with isoflurane.

PubMed

Gentilini, A; Rossoni-Gerosa, M; Frei, C W; Wymann, R; Morari, M; Zbinden, A M; Schnider, T W

2001-08-01

A model-based closed-loop control system is presented to regulate hypnosis with the volatile anesthetic isoflurane. Hypnosis is assessed by means of the bispectral index (BIS), a processed parameter derived from the electroencephalogram. Isoflurane is administered through a closed-circuit respiratory system. The model for control was identified on a population of 20 healthy volunteers. It consists of three parts: a model for the respiratory system, a pharmacokinetic model and a pharmacodynamic model to predict BIS at the effect compartment. A cascaded internal model controller is employed. The master controller compares the actual BIS and the reference value set by the anesthesiologist and provides expired isoflurane concentration references to the slave controller. The slave controller maneuvers the fresh gas anesthetic concentration entering the respiratory system. The controller is designed to adapt to different respiratory conditions. Anti-windup measures protect against performance degradation in the event of saturation of the input signal. Fault detection schemes in the controller cope with BIS and expired concentration measurement artifacts. The results of clinical studies on humans are presented.

Synthesis of a control model for a liquid nitrogen cooled, closed circuit, cryogenic nitrogen wind tunnel and its validation

NASA Technical Reports Server (NTRS)

Balakrishna, S.; Goglia, G. L.

1979-01-01

The details of the efforts to synthesize a control-compatible multivariable model of a liquid nitrogen cooled, gaseous nitrogen operated, closed circuit, cryogenic pressure tunnel are presented. The synthesized model was transformed into a real-time cryogenic tunnel simulator, and this model is validated by comparing the model responses to the actual tunnel responses of the 0.3 m transonic cryogenic tunnel, using the quasi-steady-state and the transient responses of the model and the tunnel. The global nature of the simple, explicit, lumped multivariable model of a closed circuit cryogenic tunnel is demonstrated.

Closed-Form Solutions for a Circular Tunnel in Elastic-Brittle-Plastic Ground with the Original and Generalized Hoek-Brown Failure Criteria

NASA Astrophysics Data System (ADS)

Chen, Ran; Tonon, Fulvio

2011-03-01

The paper presents a closed-form solution for the convergence curve of a circular tunnel in an elasto-brittle-plastic rock mass with both the Hoek-Brown and generalized Hoek-Brown failure criteria, and a linear flow rule, i.e., the ratio between the minor and major plastic strain increments is constant. The improvement over the original solution of Brown et al. (J Geotech Eng ASCE 109(1):15-39, 1983) consists of taking into account the elastic strain variation in the plastic annulus, which was assumed to be fixed in the original solution by Brown et al. The improvement over Carranza-Torres' solution (Int J Rock Mech Min Sci 41(Suppl 1):629-639, 2004) consists of providing a closed-form solution, rather than resorting to numerical integration of an ordinary differential equation. The presented solution, by rigorously following the theory of plasticity, takes into account that the elastic strain components change with radial and circumferential stress changes within the plastic annulus. For the original Hoek-Brown failure criterion, disregarding the elastic strain change leads to underestimate the convergence by up to 55%. For a rock mass failing according to the generalized Hoek-Brown failure criterion, using the original failure criterion leads to a high probability (97%) of underestimating the convergence by up to 100%. As a consequence, the onset or degree of squeezing may be underestimated, and the loading on the support/reinforcement calculated with the convergence/confinement method may be largely underestimated.

Did the Mississippian Lodgepole buildup at Dickinson Field (North Dakota) form as a gas seep ({open_quotes}vent{close_quotes}) community?

DOE Office of Scientific and Technical Information (OSTI.GOV)

Longman, M.W.

1996-10-01

The Lower Mississippian Lodgepole carbonate buildup reservoir at Dickinson Field in Stark County, North Dakota, has been widely reported as being a Waulsortian (or Waulsortian-like) mound. The term {open_quotes}Waulsortian mound{close_quotes} is used for a variety of Early Mississippian carbonate buildups that share a number of features including an abundance of carbonate mud, a {open_quotes}framework{close_quotes} of organisms such as fenestrate bryozoans and crinoids that tended to trap or baffle sediment, and a general absence of marine-cemented reef framework. Although the age of the Lodgepole mound at Dickinson Field qualifies it to be a Waulsortian mound, petrographic study of cores reveals thatmore » the reservoir rocks are quite unlike those in true Waulsortian mounds. Instead of being dominated by carbonate mud, the Lodgepole mound core is dominated by marine cement. Furthermore, ostracods and microbial limestones are common in the mound core where they occur with crinoid debris and small amounts of bryozoan, coral, and brachiopod debris. The abundant microbial limestones and marine cement indicate that the Dickinson mound formed as a lithified reef on the sea floor rather than as a Waulsortian mud mound. The microbial limestones, marine cement, and common ostracods in the mount core, and the fact that the mound nucleated almost directly o top of the Bakken Shale, suggest that the Dickinson Lodgepole mound formed at the site of a submarine spring and gas seep.« less

Microstructure based model for sound absorption predictions of perforated closed-cell metallic foams.

PubMed

Chevillotte, Fabien; Perrot, Camille; Panneton, Raymond

2010-10-01

Closed-cell metallic foams are known for their rigidity, lightness, thermal conductivity as well as their low production cost compared to open-cell metallic foams. However, they are also poor sound absorbers. Similarly to a rigid solid, a method to enhance their sound absorption is to perforate them. This method has shown good preliminary results but has not yet been analyzed from a microstructure point of view. The objective of this work is to better understand how perforations interact with closed-cell foam microstructure and how it modifies the sound absorption of the foam. A simple two-dimensional microstructural model of the perforated closed-cell metallic foam is presented and numerically solved. A rough three-dimensional conversion of the two-dimensional results is proposed. The results obtained with the calculation method show that the perforated closed-cell foam behaves similarly to a perforated solid; however, its sound absorption is modulated by the foam microstructure, and most particularly by the diameters of both perforation and pore. A comparison with measurements demonstrates that the proposed calculation method yields realistic trends. Some design guides are also proposed.

A Model for Developing Clinical Analytics Capacity: Closing the Loops on Outcomes to Optimize Quality.

PubMed

Eggert, Corinne; Moselle, Kenneth; Protti, Denis; Sanders, Dale

2017-01-01

Closed Loop Analytics© is receiving growing interest in healthcare as a term referring to information technology, local data and clinical analytics working together to generate evidence for improvement. The Closed Loop Analytics model consists of three loops corresponding to the decision-making levels of an organization and the associated data within each loop - Patients, Protocols, and Populations. The authors propose that each of these levels should utilize the same ecosystem of electronic health record (EHR) and enterprise data warehouse (EDW) enabled data, in a closed-loop fashion, with that data being repackaged and delivered to suit the analytic and decision support needs of each level, in support of better outcomes.

Detection of no-model input-output pairs in closed-loop systems.

PubMed

Potts, Alain Segundo; Alvarado, Christiam Segundo Morales; Garcia, Claudio

2017-11-01

The detection of no-model input-output (IO) pairs is important because it can speed up the multivariable system identification process, since all the pairs with null transfer functions are previously discarded and it can also improve the identified model quality, thus improving the performance of model based controllers. In the available literature, the methods focus just on the open-loop case, since in this case there is not the effect of the controller forcing the main diagonal in the transfer matrix to one and all the other terms to zero. In this paper, a modification of a previous method able to detect no-model IO pairs in open-loop systems is presented, but adapted to perform this duty in closed-loop systems. Tests are performed by using the traditional methods and the proposed one to show its effectiveness. Copyright © 2017 ISA. Published by Elsevier Ltd. All rights reserved.

Modelling the development of defects during composite reinforcements and prepreg forming.

PubMed

Boisse, P; Hamila, N; Madeo, A

2016-07-13

Defects in composite materials are created during manufacture to a large extent. To avoid them as much as possible, it is important that process simulations model the onset and the development of these defects. It is then possible to determine the manufacturing conditions that lead to the absence or to the controlled presence of such defects. Three types of defects that may appear during textile composite reinforcement or prepreg forming are analysed and modelled in this paper. Wrinkling is one of the most common flaws that occur during textile composite reinforcement forming processes. The influence of the different rigidities of the textile reinforcement is studied. The concept of 'locking angle' is questioned. A second type of unusual behaviour of fibrous composite reinforcements that can be seen as a flaw during their forming process is the onset of peculiar 'transition zones' that are directly related to the bending stiffness of the fibres. The 'transition zones' are due to the bending stiffness of fibres. The standard continuum mechanics of Cauchy is not sufficient to model these defects. A second gradient approach is presented that allows one to account for such unusual behaviours and to master their onset and development during forming process simulations. Finally, the large slippages that may occur during a preform forming are discussed and simulated with meso finite-element models used for macroscopic forming. This article is part of the themed issue 'Multiscale modelling of the structural integrity of composite materials'. © 2016 The Author(s).

12 CFR Appendix C to Part 41 - Model Forms for Opt-Out Notices

Code of Federal Regulations, 2012 CFR

2012-01-01

... 12 Banks and Banking 1 2012-01-01 2012-01-01 false Model Forms for Opt-Out Notices C Appendix C to... Pt. 41, App. C Appendix C to Part 41—Model Forms for Opt-Out Notices a. Although use of the model... comply with § 41.23(a)(2) of this part. C-1 Model Form for Initial Opt-out Notice (Single-Affiliate...

12 CFR Appendix C to Part 41 - Model Forms for Opt-Out Notices

Code of Federal Regulations, 2010 CFR

2010-01-01

... 12 Banks and Banking 1 2010-01-01 2010-01-01 false Model Forms for Opt-Out Notices C Appendix C to... Pt. 41, App. C Appendix C to Part 41—Model Forms for Opt-Out Notices a. Although use of the model... comply with § 41.23(a)(2) of this part. C-1 Model Form for Initial Opt-out Notice (Single-Affiliate...

Reduced-form air quality modeling for community-scale ...

EPA Pesticide Factsheets

Transportation plays an important role in modern society, but its impact on air quality has been shown to have significant adverse effects on public health. Numerous reviews (HEI, CDC, WHO) summarizing findings of hundreds of studies conducted mainly in the last decade, conclude that exposures to traffic emissions near roads are a public health concern. The Community LINE Source Model (C-LINE) is a web-based model designed to inform the community user of local air quality impacts due to roadway vehicles in their region of interest using a simplified modeling approach. Reduced-form air quality modeling is a useful tool for examining what-if scenarios of changes in emissions, such as those due to changes in traffic volume, fleet mix, or vehicle speed. Examining various scenarios of air quality impacts in this way can identify potentially at-risk populations located near roadways, and the effects that a change in traffic activity may have on them. C-LINE computes dispersion of primary mobile source pollutants using meteorological conditions for the region of interest and computes air-quality concentrations corresponding to these selected conditions. C-LINE functionality has been expanded to model emissions from port-related activities (e.g. ships, trucks, cranes, etc.) in a reduced-form modeling system for local-scale near-port air quality analysis. This presentation describes the Community modeling tools C-LINE and C-PORT that are intended to be used by local gove

SOLPS modeling of the effect on plasma detachment of closing the lower divertor in DIII-D

DOE PAGES

Sang, C. F.; Stangeby, P. C.; Guo, H. Y.; ...

2016-12-15

SOLPS modeling has been carried out to assess the effect of tightly closing the lower divertor in DIII-D, which at present is almost fully open, on the achievement of cold dissipative/detached divertor conditions. To isolate the impact of other factors on the divertor plasma solution and to make direct comparisons, most of the parameters including the meshes were kept as similar as possible. Only the neutral baffling was modified to compare a fully open divertor with a tightly closed one. The modeling shows that the tightly closed divertor greatly improves trapping of recycling neutrals, thereby increasing radiative and charge exchangemore » losses in the divertor and reducing the electron temperature T et and deposited power density q dep at the target plate. Furthermore, the closed structure enables the divertor plasma to enter into highly dissipative and detached divertor conditions at a significantly lower upstream density. The effects of divertor closure on the neutral density and pressure, and their correlation with the divertor plasma conditions are also demonstrated. The effect of molecular D 2- ion D + elastic collisions and neutral-neutral collisions on the divertor plasma solution are assessed.« less

Modelling the development of defects during composite reinforcements and prepreg forming

PubMed Central

Hamila, N.; Madeo, A.

2016-01-01

Defects in composite materials are created during manufacture to a large extent. To avoid them as much as possible, it is important that process simulations model the onset and the development of these defects. It is then possible to determine the manufacturing conditions that lead to the absence or to the controlled presence of such defects. Three types of defects that may appear during textile composite reinforcement or prepreg forming are analysed and modelled in this paper. Wrinkling is one of the most common flaws that occur during textile composite reinforcement forming processes. The influence of the different rigidities of the textile reinforcement is studied. The concept of ‘locking angle’ is questioned. A second type of unusual behaviour of fibrous composite reinforcements that can be seen as a flaw during their forming process is the onset of peculiar ‘transition zones’ that are directly related to the bending stiffness of the fibres. The ‘transition zones’ are due to the bending stiffness of fibres. The standard continuum mechanics of Cauchy is not sufficient to model these defects. A second gradient approach is presented that allows one to account for such unusual behaviours and to master their onset and development during forming process simulations. Finally, the large slippages that may occur during a preform forming are discussed and simulated with meso finite-element models used for macroscopic forming. This article is part of the themed issue ‘Multiscale modelling of the structural integrity of composite materials’. PMID:27242300

Model of wealth and goods dynamics in a closed market

NASA Astrophysics Data System (ADS)

Ausloos, Marcel; Peķalski, Andrzej

2007-01-01

A simple computer simulation model of a closed market on a fixed network with free flow of goods and money is introduced. The model contains only two variables: the amount of goods and money beside the size of the system. An initially flat distribution of both variables is presupposed. We show that under completely random rules, i.e. through the choice of interacting agent pairs on the network and of the exchange rules that the market stabilizes in time and shows diversification of money and goods. We also indicate that the difference between poor and rich agents increases for small markets, as well as for systems in which money is steadily deduced from the market through taxation. It is also found that the price of goods decreases when taxes are introduced, likely due to the less availability of money.

12 CFR Appendix B to Part 230 - Model Clauses and Sample Forms

Code of Federal Regulations, 2010 CFR

2010-01-01

... 12 Banks and Banking 3 2010-01-01 2010-01-01 false Model Clauses and Sample Forms B Appendix B to... SYSTEM TRUTH IN SAVINGS (REGULATION DD) Pt. 230, App. B Appendix B to Part 230—Model Clauses and Sample Forms Table of contents B-1—Model Clauses for Account Disclosures (Section 230.4(b)) B-2—Model Clauses...

Free-form geometric modeling by integrating parametric and implicit PDEs.

PubMed

Du, Haixia; Qin, Hong

2007-01-01

Parametric PDE techniques, which use partial differential equations (PDEs) defined over a 2D or 3D parametric domain to model graphical objects and processes, can unify geometric attributes and functional constraints of the models. PDEs can also model implicit shapes defined by level sets of scalar intensity fields. In this paper, we present an approach that integrates parametric and implicit trivariate PDEs to define geometric solid models containing both geometric information and intensity distribution subject to flexible boundary conditions. The integrated formulation of second-order or fourth-order elliptic PDEs permits designers to manipulate PDE objects of complex geometry and/or arbitrary topology through direct sculpting and free-form modeling. We developed a PDE-based geometric modeling system for shape design and manipulation of PDE objects. The integration of implicit PDEs with parametric geometry offers more general and arbitrary shape blending and free-form modeling for objects with intensity attributes than pure geometric models.

Ising model versus normal form game

NASA Astrophysics Data System (ADS)

Galam, Serge; Walliser, Bernard

2010-02-01

The 2-spin Ising model in statistical mechanics and the 2×2 normal form game in game theory are compared. All configurations allowed by the second are recovered by the first when the only concern is about Nash equilibria. But it holds no longer when Pareto optimum considerations are introduced as in the prisoner’s dilemma. This gap can nevertheless be filled by adding a new coupling term to the Ising model, even if that term has up to now no physical meaning. An individual complete bilinear objective function is thus found to be sufficient to reproduce all possible configurations of a 2×2 game. Using this one-to-one mapping new perspectives for future research in both fields can be envisioned.

12 CFR Appendix C to Part 717 - Model Forms for Opt-Out Notices

Code of Federal Regulations, 2010 CFR

2010-01-01

.... Although use of the model forms is not required, use of the model forms in this appendix (as applicable... from liability afforded by use of the model forms. These changes may not be so extensive as to affect... score” for accuracy, such as “payment history,” “credit history,” “payoff status,” or “claims history...

12 CFR Appendix C to Part 334 - Model Forms for Opt-Out Notices

Code of Federal Regulations, 2010 CFR

2010-01-01

.... Although use of the model forms is not required, use of the model forms in this Appendix (as applicable... from liability afforded by use of the model forms. These changes may not be so extensive as to affect... score” for accuracy, such as “payment history,” “credit history,” “payoff status,” or “claims history...

12 CFR Appendix C to Part 571 - Model Forms for Opt-Out Notices

Code of Federal Regulations, 2010 CFR

2010-01-01

... model forms is not required, use of the model forms in this Appendix (as applicable) complies with the... by use of the model forms. These changes may not be so extensive as to affect the substance, clarity... as “payment history,” “credit history,” “payoff status,” or “claims history.” 3. Substituting a...

A closed-loop model of the respiratory system: focus on hypercapnia and active expiration.

PubMed

Molkov, Yaroslav I; Shevtsova, Natalia A; Park, Choongseok; Ben-Tal, Alona; Smith, Jeffrey C; Rubin, Jonathan E; Rybak, Ilya A

2014-01-01

Breathing is a vital process providing the exchange of gases between the lungs and atmosphere. During quiet breathing, pumping air from the lungs is mostly performed by contraction of the diaphragm during inspiration, and muscle contraction during expiration does not play a significant role in ventilation. In contrast, during intense exercise or severe hypercapnia forced or active expiration occurs in which the abdominal "expiratory" muscles become actively involved in breathing. The mechanisms of this transition remain unknown. To study these mechanisms, we developed a computational model of the closed-loop respiratory system that describes the brainstem respiratory network controlling the pulmonary subsystem representing lung biomechanics and gas (O2 and CO2) exchange and transport. The lung subsystem provides two types of feedback to the neural subsystem: a mechanical one from pulmonary stretch receptors and a chemical one from central chemoreceptors. The neural component of the model simulates the respiratory network that includes several interacting respiratory neuron types within the Bötzinger and pre-Bötzinger complexes, as well as the retrotrapezoid nucleus/parafacial respiratory group (RTN/pFRG) representing the central chemoreception module targeted by chemical feedback. The RTN/pFRG compartment contains an independent neural generator that is activated at an increased CO2 level and controls the abdominal motor output. The lung volume is controlled by two pumps, a major one driven by the diaphragm and an additional one activated by abdominal muscles and involved in active expiration. The model represents the first attempt to model the transition from quiet breathing to breathing with active expiration. The model suggests that the closed-loop respiratory control system switches to active expiration via a quantal acceleration of expiratory activity, when increases in breathing rate and phrenic amplitude no longer provide sufficient ventilation. The model

The association of an inability to form and maintain close relationships due to a medical condition with anxiety and depressive disorders.

PubMed

Simning, Adam; Seplaki, Christopher L; Conwell, Yeates

2016-03-15

While low social support is a risk factor for mental illness, anxiety and depression's relationship with social impairment specifically resulting from a medical condition is poorly understood. We hypothesize that when a medical illness makes it difficult for people to form and maintain close relationships with others, they will be at increased risk for anxiety and depression. Two nationally representative surveys, the National Comorbidity Survey-Replication and National Latino and Asian American Study, included 6805 adults with at least one medical illness and information on social impairment attributed to a medical condition. The Composite International Diagnostic Interview evaluated a 12-month history of anxiety and depressive disorders. 8.2% of our sample had at least moderate difficulty in forming and maintaining close relationships due to a medical condition. In bivariate analyses, younger age, Latino ethnicity, less education, worse financial status, more chronic illnesses, physical health and discomfort, and problems with mobility, home management, and self-care were associated with this social impairment. In multivariable analyses accounting for possible confounders, there was a dose-dependent relationship between social impairment and the prevalence of anxiety and depression. Data are cross-sectional and our analyses are therefore unable to determine cause-and-effect relationships. Among adults with one or more medical conditions, social impairment attributed to medical illness was associated with a significantly greater odds of anxiety and depression. Further clarification of this relationship could inform more targeted, personalized interventions to prevent and/or alleviate mental illness in those with chronic medical conditions. Copyright © 2016 Elsevier B.V. All rights reserved.

Closed-form solution for the Wigner phase-space distribution function for diffuse reflection and small-angle scattering in a random medium.

PubMed

Yura, H T; Thrane, L; Andersen, P E

2000-12-01

Within the paraxial approximation, a closed-form solution for the Wigner phase-space distribution function is derived for diffuse reflection and small-angle scattering in a random medium. This solution is based on the extended Huygens-Fresnel principle for the optical field, which is widely used in studies of wave propagation through random media. The results are general in that they apply to both an arbitrary small-angle volume scattering function, and arbitrary (real) ABCD optical systems. Furthermore, they are valid in both the single- and multiple-scattering regimes. Some general features of the Wigner phase-space distribution function are discussed, and analytic results are obtained for various types of scattering functions in the asymptotic limit s > 1, where s is the optical depth. In particular, explicit results are presented for optical coherence tomography (OCT) systems. On this basis, a novel way of creating OCT images based on measurements of the momentum width of the Wigner phase-space distribution is suggested, and the advantage over conventional OCT images is discussed. Because all previous published studies regarding the Wigner function are carried out in the transmission geometry, it is important to note that the extended Huygens-Fresnel principle and the ABCD matrix formalism may be used successfully to describe this geometry (within the paraxial approximation). Therefore for completeness we present in an appendix the general closed-form solution for the Wigner phase-space distribution function in ABCD paraxial optical systems for direct propagation through random media, and in a second appendix absorption effects are included.

Towards Industrial Application of Damage Models for Sheet Metal Forming

NASA Astrophysics Data System (ADS)

Doig, M.; Roll, K.

2011-05-01

Due to global warming and financial situation the demand to reduce the CO2-emission and the production costs leads to the permanent development of new materials. In the automotive industry the occupant safety is an additional condition. Bringing these arguments together the preferable approach for lightweight design of car components, especially for body-in-white, is the use of modern steels. Such steel grades, also called advanced high strength steels (AHSS), exhibit a high strength as well as a high formability. Not only their material behavior but also the damage behavior of AHSS is different compared to the performances of standard steels. Conventional methods for the damage prediction in the industry like the forming limit curve (FLC) are not reliable for AHSS. Physically based damage models are often used in crash and bulk forming simulations. The still open question is the industrial application of these models for sheet metal forming. This paper evaluates the Gurson-Tvergaard-Needleman (GTN) model and the model of Lemaitre within commercial codes with a goal of industrial application.

Minding the close relationship.

PubMed

Harvey, J H; Omarzu, J

1997-01-01

In this theoretical analysis, we argue that a process referred to as minding is essential for a couple to feel mutually close and satisfied in a close relationship over a long period Minding represents a package of mutual self-disclosure, other forms of goal-oriented behavior aimed at facilitating the relationship, and attributions about self's and other's motivations, intentions, and Mort in the relationship. Self-disclosure and attribution activities in minding are aimed at getting to know the other, trying to understand the other's motivations and deeper disposition as they pertain to the relationship, and showing respect and acceptance for knowledge gained about other. We link the concept of minding to other major ideas and literatures about how couples achieve closeness: self-disclosure and social penetration, intimacy, empathy and empathic accuracy, and love and self-expansion. We argue that the minding process articulated here has not previously been delineated and that it is a useful composite notion about essential steps in bonding among humans. We also argue that the minding concept stretches our understanding of the interface of attribution and close relationships. We present research possibilities and implications and consider possible alternative positions and counter arguments about the merits of the minding idea for close relationship satisfaction.

Exact closed-form solution of the hyperbolic equation of string vibrations with material relaxation properties taken into account

NASA Astrophysics Data System (ADS)

Kudinov, I. V.; Kudinov, V. A.

2014-09-01

The differential equation of damped string vibrations was obtained with the finite speed of extension and strain propagation in the Hooke's law formula taken into account. In contrast to the well-known equations, the obtained equation contains the first and third time derivatives of the displacement and the mixed derivative with respect to the space and time variables. Separation of variables was used to obtain its exact closed-form solution, whose analysis showed that, for large values of the relaxation coefficient, the string return to the initial state after its escape from equilibrium is accompanied by high-frequency low-amplitude damped vibrations, which occur on the initial time interval only in the region of positive displacements. And in the limit, for some large values of the relaxation coefficient, the string return to the initial state occurs practically without any oscillatory process.

Closed loop insulin delivery in diabetes.

PubMed

Battelino, Tadej; Omladič, Jasna Šuput; Phillip, Moshe

2015-06-01

The primary goal of type 1 diabetes treatment is attaining near-normal glucose values. This currently remains out of reach for most people with type 1 diabetes despite intensified insulin treatment in the form of insulin analogues, educational interventions, continuous glucose monitoring, and sensor augmented insulin pump. The main remaining problem is risk of hypoglycaemia, which cannot be sufficiently reduced in all patient groups. Additionally, patients' burn-out often develops with years of tedious day-to-day diabetes management, rendering available diabetes-related technology less efficient. Over the past 40 years, several attempts have been made towards computer-programmed insulin delivery in the form of closed loop, with faster developments especially in the past decade. Automated insulin delivery has reduced human error in glycaemic control and considerably lessened the burden of routine self-management. In this chapter, data from randomized controlled trials with closed-loop insulin delivery that included type 1 diabetes population are summarized, and an evidence-based vision for possible routine utilization of closed loop is provided. Copyright © 2015 Elsevier Ltd. All rights reserved.

Home-Based Risk of Falling Assessment Test Using a Closed-Loop Balance Model.

PubMed

Ayena, Johannes C; Zaibi, Helmi; Otis, Martin J-D; Menelas, Bob-Antoine J

2016-12-01

The aim of this study is to improve and facilitate the methods used to assess risk of falling at home among older people through the computation of a risk of falling in real time in daily activities. In order to increase a real time computation of the risk of falling, a closed-loop balance model is proposed and compared with One-Leg Standing Test (OLST). This balance model allows studying the postural response of a person having an unpredictable perturbation. Twenty-nine volunteers participated in this study for evaluating the effectiveness of the proposed system which includes seventeen elder participants: ten healthy elderly ( 68.4 ±5.5 years), seven Parkinson's disease (PD) subjects ( 66.28 ±8.9 years), and twelve healthy young adults ( 28.27 ±3.74 years). Our work suggests that there is a relationship between OLST score and the risk of falling based on center of pressure measurement with four low cost force sensors located inside an instrumented insole, which could be predicted using our suggested closed-loop balance model. For long term monitoring at home, this system could be included in a medical electronic record and could be useful as a diagnostic aid tool.

Finite element modelling of chain-die forming for ultra-high strength steel

NASA Astrophysics Data System (ADS)

Majji, Raju; Xiang, Yang; Ding, Scott; Yang, Chunhui

2017-10-01

There has been a high demand for weight reduction in automotive vehicles while maintaining passenger safety. A potential steel material to achieve this is Ultra High Strength Steel (UHSS). As a high strength material, it is difficult to be formed with desired profiles using traditional sheet metal forming processes such as Cold Roll Forming. To overcome this problem, a potentially alternative solution is Chain-die Forming (CDF), recently developed. The basic principal of the CDF is to fully combine roll forming and bending processes. The main advantage of this process is the elongated deformation length that significantly increases effective roll radius. This study focuses on identifying issues with the CDF by using CAD modelling, Motion Analysis and Finite Element Analysis (FEA) to devise solutions and construct a more reliable process in an optimal design sense. Some attempts on finite element modelling and simulation of the CDF were conducted using relatively simple models in literature and the research was still not sufficient enough for optimal design of a typical CDF for UHSS. Therefore two numerical models of Chain-die Forming process are developed in this study, including a) one having a set of rolls similar to roll forming but with a large radius, i.e., 20 meters; and b) the other one with dies and punch segments similar to a typical CDF machine. As a case study, to form a 60° channel with single pass was conducted using these two devised models for a comparison. The obtained numerical results clearly show the CDF could generate less residual stress, low strain and small springback of a single pass for the 60° UHSS channel. The design analysis procedure proposed in this study could greatly help the mechanical designers to devise a cost-effective and reliable CDF process for forming UHSS.

Consolidation modelling for thermoplastic composites forming simulation

NASA Astrophysics Data System (ADS)

Xiong, H.; Rusanov, A.; Hamila, N.; Boisse, P.

2016-10-01

Pre-impregnated thermoplastic composites are widely used in the aerospace industry for their excellent mechanical properties, Thermoforming thermoplastic prepregs is a fast manufacturing process, the automotive industry has shown increasing interest in this manufacturing processes, in which the reconsolidation is an essential stage. The model of intimate contact is investigated as the consolidation model, compression experiments have been launched to identify the material parameters, several numerical tests show the influents of the temperature and pressure applied during processing. Finally, a new solid-shell prismatic element has been presented for the simulation of consolidation step in the thermoplastic composites forming process.

12 CFR Appendix C to Part 571 - Model Forms for Opt-Out Notices

Code of Federal Regulations, 2014 CFR

2014-01-01

... 12 Banks and Banking 6 2014-01-01 2012-01-01 true Model Forms for Opt-Out Notices C Appendix C to... REPORTING Pt. 571, App. C Appendix C to Part 571—Model Forms for Opt-Out Notices a. Although use of the... comply with § 571.23(a)(2) of this part. C-1Model Form for Initial Opt-out Notice (Single-Affiliate...

12 CFR Appendix C to Part 571 - Model Forms for Opt-Out Notices

Code of Federal Regulations, 2011 CFR

2011-01-01

... 12 Banks and Banking 5 2011-01-01 2011-01-01 false Model Forms for Opt-Out Notices C Appendix C to... REPORTING Pt. 571, App. C Appendix C to Part 571—Model Forms for Opt-Out Notices a. Although use of the... comply with § 571.23(a)(2) of this part. C-1Model Form for Initial Opt-out Notice (Single-Affiliate...

12 CFR Appendix C to Part 717 - Model Forms for Opt-Out Notices

Code of Federal Regulations, 2013 CFR

2013-01-01

... 12 Banks and Banking 7 2013-01-01 2013-01-01 false Model Forms for Opt-Out Notices C Appendix C to... FAIR CREDIT REPORTING Pt. 717, App. C Appendix C to Part 717—Model Forms for Opt-Out Notices a... the treatment of opt-outs by joint consumers to comply with § 717.23(a)(2) of this part. C-1Model Form...

12 CFR Appendix C to Part 571 - Model Forms for Opt-Out Notices

Code of Federal Regulations, 2013 CFR

2013-01-01

... 12 Banks and Banking 6 2013-01-01 2012-01-01 true Model Forms for Opt-Out Notices C Appendix C to... REPORTING Pt. 571, App. C Appendix C to Part 571—Model Forms for Opt-Out Notices a. Although use of the... comply with § 571.23(a)(2) of this part. C-1Model Form for Initial Opt-out Notice (Single-Affiliate...

12 CFR Appendix C to Part 222 - Model Forms for Opt-Out Notices

Code of Federal Regulations, 2011 CFR

2011-01-01

... 12 Banks and Banking 3 2011-01-01 2011-01-01 false Model Forms for Opt-Out Notices C Appendix C to... SYSTEM FAIR CREDIT REPORTING (REGULATION V) Pt. 222, App. C Appendix C to Part 222—Model Forms for Opt... of opt-outs by joint consumers to comply with § 222.23(a)(2) of this part. C-1Model Form for Initial...

12 CFR Appendix C to Part 717 - Model Forms for Opt-Out Notices

Code of Federal Regulations, 2011 CFR

2011-01-01

... 12 Banks and Banking 6 2011-01-01 2011-01-01 false Model Forms for Opt-Out Notices C Appendix C to... FAIR CREDIT REPORTING Pt. 717, App. C Appendix C to Part 717—Model Forms for Opt-Out Notices a... the treatment of opt-outs by joint consumers to comply with § 717.23(a)(2) of this part. C-1Model Form...

The Kroll-Lee-Zumino Model and Pion Form Factors

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dominguez, C. A.; Loewe, M.

2010-08-04

At the one loop level, we make use of the renormalizable Abelian quantum field theory model of Kroll, Lee, and Zumino (KLZ) in order to compute the vertex corrections to the tree-level, Vector Meson Dominance (VMD) electromagnetic pion form factor. This result, together with the one-loop vacuum polarization contribution, implies an electromagnetic pion form factor which is in outstanding agreement with data in the whole range of accessible momentum transfers in the space-like region. The time-like form factor, which reproduces the Gounaris-Sakurai formula at and near the rho-meson peak, remains unaffected by the vertex correction at order O(g{sup 2}). Wemore » also use the KLZ model to compute the pion scalar radius at the one loop level, finding S = 0.40 fm{sup 2}. From this value we find for the low energy constant of chiral perturbation theory l{sub 4} = 3.4.« less

Modelling microbial exchanges between forms of soil nitrogen in contrasting ecosystems

NASA Astrophysics Data System (ADS)

Pansu, M.; Machado, D.; Bottner, P.; Sarmiento, L.

2014-02-01

Although nitrogen (N) is often combined with carbon (C) in organic molecules, C passes from the air to the soil through plant photosynthesis, whereas N passes from the soil to plants through a chain of microbial conversions. However, dynamic models do not fully consider the microorganisms at the centre of exchange processes between organic and mineral forms of N. This study monitored the transfer of 14C and 15N between plant materials, microorganisms, humified compartments, and inorganic forms in six very different ecosystems along an altitudinal transect. The microbial conversions of the 15N forms appear to be strongly linked to the previously modelled C cycle, and the same equations and parameters can be used to model both C and N cycles. The only difference is in the modelling of the flows between microbial and inorganic forms. The processes of mineralization and immobilization of N appear to be regulated by a two-way microbial exchange depending on the C : N ratios of microorganisms and available substrates. The MOMOS (Modelling of Organic Matter of Soils) model has already been validated for the C cycle and also appears to be valid for the prediction of microbial transformations of N forms. This study shows that the hypothesis of microbial homeostasis can give robust predictions at global scale. However, the microbial populations did not appear to always be independent of the external constraints. At some altitudes their C : N ratio could be better modelled as decreasing during incubation and increasing with increasing C storage in cold conditions. The ratio of potentially mineralizable-15N/inorganic-15N and the 15N stock in the plant debris and the microorganisms was modelled as increasing with altitude, whereas the 15N storage in stable humus was modelled as decreasing with altitude. This predicts that there is a risk that mineralization of organic reserves in cold areas may increase global warming.

Virtual Habitat -a dynamic simulation of closed life support systems -human model status

NASA Astrophysics Data System (ADS)

Markus Czupalla, M. Sc.; Zhukov, Anton; Hwang, Su-Au; Schnaitmann, Jonas

In order to optimize Life Support Systems on a system level, stability questions must be in-vestigated. To do so the exploration group of the Technical University of Munich (TUM) is developing the "Virtual Habitat" (V-HAB) dynamic LSS simulation software. V-HAB shall provide the possibility to conduct dynamic simulations of entire mission scenarios for any given LSS configuration. The Virtual Habitat simulation tool consists of four main modules: • Closed Environment Module (CEM) -monitoring of compounds in a closed environment • Crew Module (CM) -dynamic human simulation • P/C Systems Module (PCSM) -dynamic P/C subsystems • Plant Module (PM) -dynamic plant simulation The core module of the simulation is the dynamic and environment sensitive human module. Introduced in its basic version in 2008, the human module has been significantly updated since, increasing its capabilities and maturity significantly. In this paper three newly added human model subsystems (thermal regulation, digestion and schedule controller) are introduced touching also on the human stress subsystem which is cur-rently under development. Upon the introduction of these new subsystems, the integration of these into the overall V-HAB human model is discussed, highlighting the impact on the most important I/F. The overall human model capabilities shall further be summarized and presented based on meaningful test cases. In addition to the presentation of the results, the correlation strategy for the Virtual Habitat human model shall be introduced assessing the models current confidence level and giving an outlook on the future correlation strategy. Last but not least, the remaining V-HAB mod-ules shall be introduced shortly showing how the human model is integrated into the overall simulation.

Compilation of a near-infrared library for the construction of quantitative models of amoxicillin and potassium clavulanate oral dosage forms

NASA Astrophysics Data System (ADS)

Zou, Wen-bo; Chong, Xiao-meng; Wang, Yan; Hu, Chang-qin

2018-05-01

The accuracy of NIR quantitative models depends on calibration samples with concentration variability. Conventional sample collecting methods have some shortcomings especially the time-consuming which remains a bottleneck in the application of NIR models for Process Analytical Technology (PAT) control. A study was performed to solve the problem of sample selection collection for construction of NIR quantitative models. Amoxicillin and potassium clavulanate oral dosage forms were used as examples. The aim was to find a normal approach to rapidly construct NIR quantitative models using an NIR spectral library based on the idea of a universal model [2021]. The NIR spectral library of amoxicillin and potassium clavulanate oral dosage forms was defined and consisted of spectra of 377 batches of samples produced by 26 domestic pharmaceutical companies, including tablets, dispersible tablets, chewable tablets, oral suspensions, and granules. The correlation coefficient (rT) was used to indicate the similarities of the spectra. The samples’ calibration sets were selected from a spectral library according to the median rT of the samples to be analyzed. The rT of the samples selected was close to the median rT. The difference in rT of those samples was 1.0% to 1.5%. We concluded that sample selection is not a problem when constructing NIR quantitative models using a spectral library versus conventional methods of determining universal models. The sample spectra with a suitable concentration range in the NIR models were collected quickly. In addition, the models constructed through this method were more easily targeted.

Usefulness of thermographic analysis to control temperature homogeneity in the development and implementation of a closed recirculating CO2 chemohyperthermia model.

PubMed

Padilla-Valverde, David; Sanchez-Garcia, Susana; García-Santos, Esther; Marcote-Ibañez, Carlos; Molina-Robles, Mercedes; Martín-Fernández, Jesús; Villarejo-Campos, Pedro

2016-09-30

To determine the effectiveness of thermography to control the distribution of abdominal temperature in the development of a closed chemohyperthermia model. For thermographic analysis, we divided the abdominopelvic cavity into nine regions according to a modification of carcinomatosis peritoneal index. A difference of 2.5 °C between and within the quadrants, and thermographic colours, were used as asymmetric criteria. Preclinical study:· Rats Model: Six athymic nude rats, male, rnu/rnu. They were treated with closed technique and open technique. Porcine Model: 12 female large white pigs. Four were treated with open technique and eight with closed recirculation CO 2 technique. Clinical Pilot Study, EUDRACT 2011-006319-69: 18 patients with ovarian cancer were treated with cytoreductive surgery and hyperthermia intraperitoneal chemotherapy, HIPEC, with a closed recirculating CO 2 system. Thermographic control and intra-abdominal temperature assessment was performed at the baseline, when outflow temperature reached 41 °C, and at 30´. The thermographic images showed a higher homogeneity of the intra-abdominal temperature in the closed model respect to the open technique. The thermogram showed a temperature distribution homogeneity when starting the circulation of chemotherapy. There was correlation between the temperature thermographic map in the closed porcine model and pilot study, and reached inflow and outflow temperatures, at half time of HIPEC, of 42/41.4 °C and 42 ± 0.2/41 ± 0.8 °C, respectively. There was no significant impact to the core temperature of patients after reaching the homogeneous temperature distribution. To control homogeneity of temperature distribution is feasible using infra-red digital images in a closed HIPEC with CO 2 recirculation.

Scenario-based, closed-loop model predictive control with application to emergency vehicle scheduling

NASA Astrophysics Data System (ADS)

Goodwin, Graham. C.; Medioli, Adrian. M.

2013-08-01

Model predictive control has been a major success story in process control. More recently, the methodology has been used in other contexts, including automotive engine control, power electronics and telecommunications. Most applications focus on set-point tracking and use single-sequence optimisation. Here we consider an alternative class of problems motivated by the scheduling of emergency vehicles. Here disturbances are the dominant feature. We develop a novel closed-loop model predictive control strategy aimed at this class of problems. We motivate, and illustrate, the ideas via the problem of fluid deployment of ambulance resources.

Birkhoff Normal Form for Some Nonlinear PDEs

NASA Astrophysics Data System (ADS)

Bambusi, Dario

We consider the problem of extending to PDEs Birkhoff normal form theorem on Hamiltonian systems close to nonresonant elliptic equilibria. As a model problem we take the nonlinear wave equation FORM="DISPLAY" DISC="MATH"> with Dirichlet boundary conditions on [0,π] g is an analytic skewsymmetric function which vanishes for u=0 and is periodic with period 2π in the x variable. We prove, under a nonresonance condition which is fulfilled for most g's, that for any integer M there exists a canonical transformation that puts the Hamiltonian in Birkhoff normal form up to a reminder of order M. The canonical transformation is well defined in a neighbourhood of the origin of a Sobolev type phase space of sufficiently high order. Some dynamical consequences are obtained. The technique of proof is applicable to quite general semilinear equations in one space dimension.

WHEN DID ROUND DISK GALAXIES FORM?

DOE Office of Scientific and Technical Information (OSTI.GOV)

Takeuchi, T. M.; Ohta, K.; Yuma, S.

2015-03-01

When and how galaxy morphology, such as the disk and bulge seen in the present-day universe, emerged is still not clear. In the universe at z ≳ 2, galaxies with various morphologies are seen, and star-forming galaxies at z ∼ 2 show the intrinsic shape of bar-like structures. Then, when did the round disk structure form? Here we take a simple and straightforward approach to see the epoch when a round disk galaxy population emerged by constraining the intrinsic shape statistically based on the apparent axial ratio distribution of galaxies. We derived the distributions of the apparent axial ratios inmore » the rest-frame optical light (∼5000 Å) of star-forming main-sequence galaxies at 2.5 > z > 1.4, 1.4 > z > 0.85, and 0.85 > z > 0.5, and found that their apparent axial ratios show peaky distributions at z ≳ 0.85, while a rather flat distribution at the lower redshift. By using a tri-axial model (A > B > C) for the intrinsic shape, we found that the best-fit models give the peaks of the B/A distribution of 0.81 ± 0.04, 0.84 ± 0.04, and 0.92 ± 0.05 at 2.5 > z > 1.4, 1.4 > z > 0.85, and 0.85 > z > 0.5, respectively. The last value is close to the local value of 0.95. Thickness (C/A) is ∼0.25 at all the redshifts and is close to the local value (0.21). The results indicate that the shape of the star-forming galaxies in the main sequence changes gradually, and that the round disk is established at around z ∼ 0.9. The establishment of the round disk may be due to the cessation of a violent interaction between galaxies or the growth of a bulge and/or a supermassive black hole residing at the center of a galaxy that dissolves the bar structure.« less

Numerical modeling of cold room's hinged door opening and closing processes

NASA Astrophysics Data System (ADS)

Carneiro, R.; Gaspar, P. D.; Silva, P. D.; Domingues, L. C.

2016-06-01

The need of rationalize energy consumption in agrifood industry has fasten the development of methodologies to improve the thermal and energy performances of cold rooms. This paper presents a three-dimensional (3D) transient Computational Fluid Dynamics (CFD) modelling of a cold room to evaluate the air infiltration rate through hinged doors. A species transport model is used for modelling the tracer gas concentration decay technique. Numerical predictions indicate that air temperature difference between spaces affects the air infiltration. For this case study, the infiltration rate increases 0.016 m3 s-1 per K of air temperature difference. The knowledge about the evolution of air infiltration during door opening/closing times allows to draw some conclusions about its influence on the air conditions inside the cold room, as well as to suggest best practices and simple technical improvements that can minimize air infiltration, and consequently improve thermal performance and energy consumption rationalization.

The use of normal forms for analysing nonlinear mechanical vibrations

PubMed Central

Neild, Simon A.; Champneys, Alan R.; Wagg, David J.; Hill, Thomas L.; Cammarano, Andrea

2015-01-01

A historical introduction is given of the theory of normal forms for simplifying nonlinear dynamical systems close to resonances or bifurcation points. The specific focus is on mechanical vibration problems, described by finite degree-of-freedom second-order-in-time differential equations. A recent variant of the normal form method, that respects the specific structure of such models, is recalled. It is shown how this method can be placed within the context of the general theory of normal forms provided the damping and forcing terms are treated as unfolding parameters. The approach is contrasted to the alternative theory of nonlinear normal modes (NNMs) which is argued to be problematic in the presence of damping. The efficacy of the normal form method is illustrated on a model of the vibration of a taut cable, which is geometrically nonlinear. It is shown how the method is able to accurately predict NNM shapes and their bifurcations. PMID:26303917

Dancing to CHANGA: a self-consistent prediction for close SMBH pair formation time-scales following galaxy mergers

NASA Astrophysics Data System (ADS)

Tremmel, M.; Governato, F.; Volonteri, M.; Quinn, T. R.; Pontzen, A.

2018-04-01

We present the first self-consistent prediction for the distribution of formation time-scales for close supermassive black hole (SMBH) pairs following galaxy mergers. Using ROMULUS25, the first large-scale cosmological simulation to accurately track the orbital evolution of SMBHs within their host galaxies down to sub-kpc scales, we predict an average formation rate density of close SMBH pairs of 0.013 cMpc-3 Gyr-1. We find that it is relatively rare for galaxy mergers to result in the formation of close SMBH pairs with sub-kpc separation and those that do form are often the result of Gyr of orbital evolution following the galaxy merger. The likelihood and time-scale to form a close SMBH pair depends strongly on the mass ratio of the merging galaxies, as well as the presence of dense stellar cores. Low stellar mass ratio mergers with galaxies that lack a dense stellar core are more likely to become tidally disrupted and deposit their SMBH at large radii without any stellar core to aid in their orbital decay, resulting in a population of long-lived `wandering' SMBHs. Conversely, SMBHs in galaxies that remain embedded within a stellar core form close pairs in much shorter time-scales on average. This time-scale is a crucial, though often ignored or very simplified, ingredient to models predicting SMBH mergers rates and the connection between SMBH and star formation activity.

Hybrid Modeling for Testing Intelligent Software for Lunar-Mars Closed Life Support

NASA Technical Reports Server (NTRS)

Malin, Jane T.; Nicholson, Leonard S. (Technical Monitor)

1999-01-01

Intelligent software is being developed for closed life support systems with biological components, for human exploration of the Moon and Mars. The intelligent software functions include planning/scheduling, reactive discrete control and sequencing, management of continuous control, and fault detection, diagnosis, and management of failures and errors. Four types of modeling information have been essential to system modeling and simulation to develop and test the software and to provide operational model-based what-if analyses: discrete component operational and failure modes; continuous dynamic performance within component modes, modeled qualitatively or quantitatively; configuration of flows and power among components in the system; and operations activities and scenarios. CONFIG, a multi-purpose discrete event simulation tool that integrates all four types of models for use throughout the engineering and operations life cycle, has been used to model components and systems involved in the production and transfer of oxygen and carbon dioxide in a plant-growth chamber and between that chamber and a habitation chamber with physicochemical systems for gas processing.

Viscous and thermal modelling of thermoplastic composites forming process

NASA Astrophysics Data System (ADS)

Guzman, Eduardo; Liang, Biao; Hamila, Nahiene; Boisse, Philippe

2016-10-01

Thermoforming thermoplastic prepregs is a fast manufacturing process. It is suitable for automotive composite parts manufacturing. The simulation of thermoplastic prepreg forming is achieved by alternate thermal and mechanical analyses. The thermal properties are obtained from a mesoscopic analysis and a homogenization procedure. The forming simulation is based on a viscous-hyperelastic approach. The thermal simulations define the coefficients of the mechanical model that depend on the temperature. The forming simulations modify the boundary conditions and the internal geometry of the thermal analyses. The comparison of the simulation with an experimental thermoforming of a part representative of automotive applications shows the efficiency of the approach.

Forest forming process and dynamic vegetation models under global change

Treesearch

A. Shvidenko; E. Gustafson

2009-01-01

The paper analyzes mathematical models that are used to project the dynamics of forest ecosystems on different spatial and temporal scales. Landscape disturbance and succession models (LDSMs) are of a particular interest for studying the forest forming process in Northern Eurasia. They have a solid empirical background and are able to model ecological processes under...

Atmosphere behavior in gas-closed mouse-algal systems: An experimental and modelling study

NASA Astrophysics Data System (ADS)

Averner, Maurice M.; Moore, Berrien; Bartholomew, Irene; Wharton, Robert

Concepts of biologically-based regenerative life support systems anticipate the use of photosynthetic organisms for air revitalization. However, mismatches in the rates of production and uptake of oxygen or carbon dioxide between the crew and the plants will lead to an accumulation or depletion of these gases beyond tolerable limits. One method for correcting these atmospheric changes is to use physicochemical devices. This would conflict with the constraint of minimal size and weight imposed upon the successful development of a competitive bioregenerative system. An alternate control strategy is based upon reducing the gas exchange mismatch by manipulation of those environmental parameters known to affect plant or algae gas exchange ratios. We have initiated a research program using a dual approach of mathematical modelling and laboratory experimentation aimed at examining the gas exchange characteristics of artificial animal/plant systems closed to the ambient atmosphere. Our goal is to develop control techniques and management strategies for maintaining the atmospheric levels of carbon dioxide and oxygen at physiological levels. A mathematical model simulating the atmospheric behavior in these systems has been developed and an experimental gas-closed system has been constructed. These will be described and preliminary results will be presented.

12 CFR Appendix G to Part 1026 - Open-End Model Forms and Clauses

Code of Federal Regulations, 2013 CFR

2013-01-01

... 12 Banks and Banking 8 2013-01-01 2013-01-01 false Open-End Model Forms and Clauses G Appendix G...) Pt. 1026, App. G Appendix G to Part 1026—Open-End Model Forms and Clauses G-1Balance Computation Methods Model Clauses (Home-equity Plans) (§§ 1026.6 and 1026.7) G-1(A)Balance Computation Methods Model...

12 CFR Appendix G to Part 1026 - Open-End Model Forms and Clauses

Code of Federal Regulations, 2012 CFR

2012-01-01

... 12 Banks and Banking 8 2012-01-01 2012-01-01 false Open-End Model Forms and Clauses G Appendix G...) Pt. 1026, App. G Appendix G to Part 1026—Open-End Model Forms and Clauses G-1Balance Computation Methods Model Clauses (Home-equity Plans) (§§ 1026.6 and 1026.7) G-1(A)Balance Computation Methods Model...

12 CFR Appendix G to Part 1026 - Open-End Model Forms and Clauses

Code of Federal Regulations, 2014 CFR

2014-01-01

... 12 Banks and Banking 9 2014-01-01 2014-01-01 false Open-End Model Forms and Clauses G Appendix G...) Pt. 1026, App. G Appendix G to Part 1026—Open-End Model Forms and Clauses G-1Balance Computation Methods Model Clauses (Home-equity Plans) (§§ 1026.6 and 1026.7) G-1(A)Balance Computation Methods Model...

Inflation in a closed universe

NASA Astrophysics Data System (ADS)

Ratra, Bharat

2017-11-01

To derive a power spectrum for energy density inhomogeneities in a closed universe, we study a spatially-closed inflation-modified hot big bang model whose evolutionary history is divided into three epochs: an early slowly-rolling scalar field inflation epoch and the usual radiation and nonrelativistic matter epochs. (For our purposes it is not necessary to consider a final dark energy dominated epoch.) We derive general solutions of the relativistic linear perturbation equations in each epoch. The constants of integration in the inflation epoch solutions are determined from de Sitter invariant quantum-mechanical initial conditions in the Lorentzian section of the inflating closed de Sitter space derived from Hawking's prescription that the quantum state of the universe only include field configurations that are regular on the Euclidean (de Sitter) sphere section. The constants of integration in the radiation and matter epoch solutions are determined from joining conditions derived by requiring that the linear perturbation equations remain nonsingular at the transitions between epochs. The matter epoch power spectrum of gauge-invariant energy density inhomogeneities is not a power law, and depends on spatial wave number in the way expected for a generalization to the closed model of the standard flat-space scale-invariant power spectrum. The power spectrum we derive appears to differ from a number of other closed inflation model power spectra derived assuming different (presumably non de Sitter invariant) initial conditions.

Correlation techniques to determine model form in robust nonlinear system realization/identification

NASA Technical Reports Server (NTRS)

Stry, Greselda I.; Mook, D. Joseph

1991-01-01

The fundamental challenge in identification of nonlinear dynamic systems is determining the appropriate form of the model. A robust technique is presented which essentially eliminates this problem for many applications. The technique is based on the Minimum Model Error (MME) optimal estimation approach. A detailed literature review is included in which fundamental differences between the current approach and previous work is described. The most significant feature is the ability to identify nonlinear dynamic systems without prior assumption regarding the form of the nonlinearities, in contrast to existing nonlinear identification approaches which usually require detailed assumptions of the nonlinearities. Model form is determined via statistical correlation of the MME optimal state estimates with the MME optimal model error estimates. The example illustrations indicate that the method is robust with respect to prior ignorance of the model, and with respect to measurement noise, measurement frequency, and measurement record length.

PROCESS OF FORMING POWDERED MATERIAL

DOEpatents

Glatter, J.; Schaner, B.E.

1961-07-14

A process of forming high-density compacts of a powdered ceramic material is described by agglomerating the powdered ceramic material with a heat- decompossble binder, adding a heat-decompossble lubricant to the agglomerated material, placing a quantity of the material into a die cavity, pressing the material to form a compact, pretreating the compacts in a nonoxidizing atmosphere to remove the binder and lubricant, and sintering the compacts. When this process is used for making nuclear reactor fuel elements, the ceramic material is an oxide powder of a fissionsble material and after forming, the compacts are placed in a cladding tube which is closed at its ends by vapor tight end caps, so that the sintered compacts are held in close contact with each other and with the interior wall of the cladding tube.

Water Vapor Effects on Silica-Forming Ceramics

NASA Technical Reports Server (NTRS)

Opila, E. J.; Greenbauer-Seng, L. (Technical Monitor)

2000-01-01

Silica-forming ceramics such as SiC and Si3N4 are proposed for applications in combustion environments. These environments contain water vapor as a product of combustion. Oxidation of silica-formers is more rapid in water vapor than in oxygen. Parabolic oxidation rates increase with the water vapor partial pressure with a power law exponent value close to one. Molecular water vapor is therefore the mobile species in silica. Rapid oxidation rates and large amounts of gases generated during the oxidation reaction in high water vapor pressures may result in bubble formation in the silica and nonprotective scale formation. It is also shown that silica reacts with water vapor to form Si(OH)4(g). Silica volatility has been modeled using a laminar flow boundary layer controlled reaction equation. Silica volatility depends on the partial pressure of water vapor, the total pressure, and the gas velocity. Simultaneous oxidation and volatilization reactions have been modeled with paralinear kinetics.

Models of Voltage-Dependent Conformational Changes in NaChBac Channels

PubMed Central

Shafrir, Yinon; Durell, Stewart R.; Guy, H. Robert

2008-01-01

Models of the transmembrane region of the NaChBac channel were developed in two open/inactivated and several closed conformations. Homology models of NaChBac were developed using crystal structures of Kv1.2 and a Kv1.2/2.1 chimera as templates for open conformations, and MlotiK and KcsA channels as templates for closed conformations. Multiple molecular-dynamic simulations were performed to refine and evaluate these models. A striking difference between the S4 structures of the Kv1.2-like open models and MlotiK-like closed models is the secondary structure. In the open model, the first part of S4 forms an α-helix, and the last part forms a 310 helix, whereas in the closed model, the first part of S4 forms a 310 helix, and the last part forms an α-helix. A conformational change that involves this type of transition in secondary structure should be voltage-dependent. However, this transition alone is not sufficient to account for the large gating charge movement reported for NaChBac channels and for experimental results in other voltage-gated channels. To increase the magnitude of the motion of S4, we developed another model of an open/inactivated conformation, in which S4 is displaced farther outward, and a number of closed models in which S4 is displaced farther inward. A helical screw motion for the α-helical part of S4 and a simple axial translation for the 310 portion were used to develop models of these additional conformations. In our models, four positively charged residues of S4 moved outwardly during activation, across a transition barrier formed by highly conserved hydrophobic residues on S1, S2, and S3. The S4 movement was coupled to an opening of the activation gate formed by S6 through interactions with the segment linking S4 to S5. Consistencies of our models with experimental studies of NaChBac and Kv channels are discussed. PMID:18641074

Introducing and Sustaining Close Reading and Writing through Poetry

ERIC Educational Resources Information Center

Timmermans, Karren M.; Johnson, Angie

2017-01-01

Close reading of poetry scaffolds readers and writers as they come to understand the form and function of poetry and transfer those skills to writing. In this teaching tip, the authors explain a way in which primary teachers can introduce close reading and move young students toward composing and presenting poetry.

Pole-zero form fractional model identification in frequency domain

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mansouri, R.; Djamah, T.; Djennoune, S.

2009-03-05

This paper deals with system identification in the frequency domain using non integer order models given in the pole-zero form. The usual identification techniques cannot be used in this case because of the non integer orders of differentiation which makes the problem strongly nonlinear. A general identification method based on Levenberg-Marquardt algorithm is developed and allows to estimate the (2n+2m+1) parameters of the model. Its application to identify the ''skin effect'' of a squirrel cage induction machine modeling is then presented.

[Closed-loop management model of clinical investigational product for new drug of traditional Chinese medicine].

PubMed

Wu, Ping; Zhang, Jian-Wu

2013-09-01

This paper discussed the management regulations and technical requirements of clinical investigational product for new drug of traditional Chinese medicine, analyzed some common problems on the management of them, and proposed the establishment of closed-loop management model and management requirements in various aspects.

Igneous proceses and closed system evolution of the Tharsis region of Mars

NASA Astrophysics Data System (ADS)

Finnerty, A. A.; Phillips, R. J.; Banerdt, W. B.

1988-09-01

A quantitative petrologic model for the evolution of the Tharsis region on Mars is presented, which is consistent with global gravity and topography data. It is demonstrated that it is possible to form and support the topographic relief of the Tharsis plateau by a closed-system mass-conservative nearly isostatic process involving generation of magmas from a mantle source region. Extrusion and/or intrusion (or underplating) of such magmas allows low-pressure solidification, with a consequent increase in volume relative to that which would be possible in the high-pressure source region, leading to elevated topology. The distribution of densities with depth obtained by the model is quantitatively consistent with the isostatic models of Sleep and Phillips (1979, 1985).

The Influence of Closeness Centrality on Lexical Processing

PubMed Central

Goldstein, Rutherford; Vitevitch, Michael S.

2017-01-01

The present study examined how the network science measure known as closeness centrality (which measures the average distance between a node and all other nodes in the network) influences lexical processing. In the mental lexicon, a word such as CAN has high closeness centrality, because it is close to many other words in the lexicon. Whereas, a word such as CURE has low closeness centrality because it is far from other words in the lexicon. In an auditory lexical decision task (Experiment 1) participants responded more quickly to words with high closeness centrality. In Experiment 2 an auditory lexical decision task was again used, but with a wider range of stimulus characteristics. Although, there was no main effect of closeness centrality in Experiment 2, an interaction between closeness centrality and frequency of occurrence was observed on reaction times. The results are explained in terms of partial activation gradually strengthening over time word-forms that are centrally located in the phonological network. PMID:29018396

12 CFR Appendix G to Part 226 - Open-End Model Forms and Clauses

Code of Federal Regulations, 2013 CFR

2013-01-01

... 12 Banks and Banking 3 2013-01-01 2013-01-01 false Open-End Model Forms and Clauses G Appendix G... RESERVE SYSTEM (CONTINUED) TRUTH IN LENDING (REGULATION Z) Pt. 226, App. G Appendix G to Part 226—Open-End Model Forms and Clauses G-1Balance Computation Methods Model Clauses (Home-equity Plans) (§§ 226.6 and...

12 CFR Appendix G to Part 226 - Open-End Model Forms and Clauses

Code of Federal Regulations, 2012 CFR

2012-01-01

... 12 Banks and Banking 3 2012-01-01 2012-01-01 false Open-End Model Forms and Clauses G Appendix G... RESERVE SYSTEM TRUTH IN LENDING (REGULATION Z) Pt. 226, App. G Appendix G to Part 226—Open-End Model Forms and Clauses G-1Balance Computation Methods Model Clauses (Home-equity Plans) (§§ 226.6 and 226.7) G-1...

Closed-loop stability of linear quadratic optimal systems in the presence of modeling errors

NASA Technical Reports Server (NTRS)

Toda, M.; Patel, R.; Sridhar, B.

1976-01-01

The well-known stabilizing property of linear quadratic state feedback design is utilized to evaluate the robustness of a linear quadratic feedback design in the presence of modeling errors. Two general conditions are obtained for allowable modeling errors such that the resulting closed-loop system remains stable. One of these conditions is applied to obtain two more particular conditions which are readily applicable to practical situations where a designer has information on the bounds of modeling errors. Relations are established between the allowable parameter uncertainty and the weighting matrices of the quadratic performance index, thereby enabling the designer to select appropriate weighting matrices to attain a robust feedback design.

Movement Forms: A Graph-Dynamic Perspective.

PubMed

Saltzman, Elliot; Holt, Ken

2014-01-01

The focus of this paper is on characterizing the physical movement forms (e.g., walk, crawl, roll, etc.) that can be used to actualize abstract, functionally-specified behavioral goals (e.g., locomotion). Emphasis is placed on how such forms are distinguished from one another, in part, by the set of topological patterns of physical contact between agent and environment (i.e., the set of physical graphs associated with each form) and the transitions among these patterns displayed over the course of performance (i.e., the form's physical graph dynamics ). Crucial in this regard is the creation and dissolution of loops in these graphs, which can be related to the distinction between open and closed kinematic chains. Formal similarities are described within the theoretical framework of task-dynamics between physically-closed kinematic chains (physical loops) that are created during various movement forms and functionally-closed kinematic chains (functional loops) that are associated with task-space control of end-effectors; it is argued that both types of loop must be flexibly incorporated into the coordinative structures that govern skilled action. Final speculation is focused on the role of graphs and their dynamics, not only in processes of coordination and control for individual agents, but also in processes of inter-agent coordination and the coupling of agents with (non-sentient) environmental objects.

High-entropy alloys in hexagonal close-packed structure

DOE PAGES

Gao, Michael C.; Zhang, B.; Guo, S. M.; ...

2015-08-28

The microstructures and properties of high-entropy alloys (HEAs) based on the face-centered cubic and body-centered cubic structures have been studied extensively in the literature, but reports on HEAs in the hexagonal close-packed (HCP) structure are very limited. Using an efficient strategy in combining phase diagram inspection, CALPHAD modeling, and ab initio molecular dynamics simulations, a variety of new compositions are suggested that may hold great potentials in forming single-phase HCP HEAs that comprise rare earth elements and transition metals, respectively. Lastly, experimental verification was carried out on CoFeReRu and CoReRuV using X-ray diffraction, scanning electron microscopy, and energy dispersion spectroscopy.

Paleodynamics of large closed lakes as a standard for climate modeling data verification

NASA Astrophysics Data System (ADS)

Kislov, Alexander

2015-04-01

Observed and reconstructed variations of large lakes can serve as a standard for assessing the quality of the model run off simulated by climate models. It provides the opportunity to assess whether models designed for future scenarios are skillful in 'out-of sample' climate change experiments. Based on general ideas about the laws of temporal dynamics relating to massive inertial objects, slow changes of the lake level under the semi-steady climate state can be represented as resulting from the accumulation of small anomalies in the water regime; it appears like a kind of "self-developing" system. To test this hypothesis, the water balance model of the Caspian Sea (CS) was used. Time scale for the CS is estimated as ~20 years. Model is interpreted as stochastic, and from this perspective, it is a Langevin equation that incorporates the action of precipitation and evaporation like random white noise, so that the whole can be thought of as an analogue of Brownian motion. Under these conditions, the CS palaeostages during the Holocene is represented by a system undergoing random walk. It should be emphasized that modeling results are interpreted from the probabilistic point of view, despite the fact that the model is deterministically based on the physical law of conservation of water mass. Despite the CS, another candidate to be as a potential evaluation tool for climate model simulations is the Black Sea (BS) until its merger with the Mediterranean. Therefore, although the image of the CS, BS and other lakes within the climate models is very simplified (or absent), changes in the levels could be used to assess the ability of climate models to reproduce the water budget over the catchment areas. For the CS or the BS, they are the large parts of the East European Plane and can be as indicators of climate model quality. However, the use of reconstructed data of other closed lakes is problematic. It is due to its water budget components cannot be simulated with needed

Closed-Form and Numerically-Stable Solutions to Problems Related to the Optimal Two-Impulse Transfer Between Specified Terminal States of Keplerian Orbits

NASA Technical Reports Server (NTRS)

Senent, Juan

2011-01-01

The first part of the paper presents some closed-form solutions to the optimal two-impulse transfer between fixed position and velocity vectors on Keplerian orbits when some constraints are imposed on the magnitude of the initial and final impulses. Additionally, a numerically-stable gradient-free algorithm with guaranteed convergence is presented for the minimum delta-v two-impulse transfer. In the second part of the paper, cooperative bargaining theory is used to solve some two-impulse transfer problems when the initial and final impulses are carried by different vehicles or when the goal is to minimize the delta-v and the time-of-flight at the same time.

Is the linear modeling technique good enough for optimal form design? A comparison of quantitative analysis models.

PubMed

Lin, Yang-Cheng; Yeh, Chung-Hsing; Wang, Chen-Cheng; Wei, Chun-Chun

2012-01-01

How to design highly reputable and hot-selling products is an essential issue in product design. Whether consumers choose a product depends largely on their perception of the product image. A consumer-oriented design approach presented in this paper helps product designers incorporate consumers' perceptions of product forms in the design process. The consumer-oriented design approach uses quantification theory type I, grey prediction (the linear modeling technique), and neural networks (the nonlinear modeling technique) to determine the optimal form combination of product design for matching a given product image. An experimental study based on the concept of Kansei Engineering is conducted to collect numerical data for examining the relationship between consumers' perception of product image and product form elements of personal digital assistants (PDAs). The result of performance comparison shows that the QTTI model is good enough to help product designers determine the optimal form combination of product design. Although the PDA form design is used as a case study, the approach is applicable to other consumer products with various design elements and product images. The approach provides an effective mechanism for facilitating the consumer-oriented product design process.

Is the Linear Modeling Technique Good Enough for Optimal Form Design? A Comparison of Quantitative Analysis Models

PubMed Central

Lin, Yang-Cheng; Yeh, Chung-Hsing; Wang, Chen-Cheng; Wei, Chun-Chun

2012-01-01

How to design highly reputable and hot-selling products is an essential issue in product design. Whether consumers choose a product depends largely on their perception of the product image. A consumer-oriented design approach presented in this paper helps product designers incorporate consumers' perceptions of product forms in the design process. The consumer-oriented design approach uses quantification theory type I, grey prediction (the linear modeling technique), and neural networks (the nonlinear modeling technique) to determine the optimal form combination of product design for matching a given product image. An experimental study based on the concept of Kansei Engineering is conducted to collect numerical data for examining the relationship between consumers' perception of product image and product form elements of personal digital assistants (PDAs). The result of performance comparison shows that the QTTI model is good enough to help product designers determine the optimal form combination of product design. Although the PDA form design is used as a case study, the approach is applicable to other consumer products with various design elements and product images. The approach provides an effective mechanism for facilitating the consumer-oriented product design process. PMID:23258961

A photochemical kinetic model for solid dosage forms.

PubMed

Carvalho, Thiago C; La Cruz, Thomas E; Tábora, Jose E

2017-11-01

Photochemical kinetic models to describe the solution phase degradation of pharmaceutical compounds have been extensively reported, but formalisms applicable to the solid phase under polychromatic light have not received as much attention. The objective of this study was to develop a mathematical model to describe the solid state photodegradation of pharmaceutical powder materials under different area/volumetric scales and light exposure conditions. The model considered the previous formalism presented for photodegradation kinetics in solution phase with important elements applied to static powder material being irradiated with a polychromatic light source. The model also included the influence of optical phenomena (i.e. reflectance, scattering factors, etc.) by applying Beer-Lambert law to light attenuation, including effects of powder density. Drug substance and drug product intermediates (blends and tablet cores) were exposed to different light sources and intensities. The model reasonably predicted the photodegradation levels of powder beds of drug substance and drug product intermediates under white and yellow lights with intensities around 5-11kLux. Importantly, the model estimates demonstrated that the reciprocity law for photoreactions was held. Further model evaluation showed that, due to light attenuation, the powder bed is in virtual darkness at cake depths greater than 500μm. At 100μm, the photodegradation of the investigated compound is expected to be close to 100% in 10days under white fluorescent halophosphate light at 9.5kLux. For tablets, defining the volume over exposed surface area ratio is more challenging. Nevertheless, the model can consider a bracket between worst and best cases to provide a reasonable photodegradation estimate. This tool can be significantly leveraged to simulate different light exposure scenarios while assessing photostability risk in order to define appropriate control strategy in manufacturing. Copyright © 2017

Thermal form-factor approach to dynamical correlation functions of integrable lattice models

NASA Astrophysics Data System (ADS)

Göhmann, Frank; Karbach, Michael; Klümper, Andreas; Kozlowski, Karol K.; Suzuki, Junji

2017-11-01

We propose a method for calculating dynamical correlation functions at finite temperature in integrable lattice models of Yang-Baxter type. The method is based on an expansion of the correlation functions as a series over matrix elements of a time-dependent quantum transfer matrix rather than the Hamiltonian. In the infinite Trotter-number limit the matrix elements become time independent and turn into the thermal form factors studied previously in the context of static correlation functions. We make this explicit with the example of the XXZ model. We show how the form factors can be summed utilizing certain auxiliary functions solving finite sets of nonlinear integral equations. The case of the XX model is worked out in more detail leading to a novel form-factor series representation of the dynamical transverse two-point function.

EnKF with closed-eye period - bridging intermittent model structural errors in soil hydrology

NASA Astrophysics Data System (ADS)

Bauser, Hannes H.; Jaumann, Stefan; Berg, Daniel; Roth, Kurt

2017-04-01

The representation of soil water movement exposes uncertainties in all model components, namely dynamics, forcing, subscale physics and the state itself. Especially model structural errors in the description of the dynamics are difficult to represent and can lead to an inconsistent estimation of the other components. We address the challenge of a consistent aggregation of information for a manageable specific hydraulic situation: a 1D soil profile with TDR-measured water contents during a time period of less than 2 months. We assess the uncertainties for this situation and detect initial condition, soil hydraulic parameters, small-scale heterogeneity, upper boundary condition, and (during rain events) the local equilibrium assumption by the Richards equation as the most important ones. We employ an iterative Ensemble Kalman Filter (EnKF) with an augmented state. Based on a single rain event, we are able to reduce all uncertainties directly, except for the intermittent violation of the local equilibrium assumption. We detect these times by analyzing the temporal evolution of estimated parameters. By introducing a closed-eye period - during which we do not estimate parameters, but only guide the state based on measurements - we can bridge these times. The introduced closed-eye period ensured constant parameters, suggesting that they resemble the believed true material properties. The closed-eye period improves predictions during periods when the local equilibrium assumption is met, but consequently worsens predictions when the assumption is violated. Such a prediction requires a description of the dynamics during local non-equilibrium phases, which remains an open challenge.

Closed-form analytical solutions for assessing the consequences of sea-level rise on unconfined sloping island aquifers

NASA Astrophysics Data System (ADS)

Chesnaux, R.

2016-04-01

Closed-form analytical solutions for assessing the consequences of sea-level rise on fresh groundwater oceanic island lenses are provided for the cases of both strip and circular islands. Solutions are proposed for directly calculating the change in the thickness of the lens, the changes in volume and the changes in travel time of fresh groundwater within island aquifers. The solutions apply for homogenous aquifers recharged by surface infiltration and discharged by a down-gradient, fixed-head boundary. They also take into account the inland shift of the ocean due to land surface inundation, this shift being determined by the coastal slope of inland aquifers. The solutions are given for two simple island geometries: circular islands and strip islands. Base case examples are presented to illustrate, on one hand, the amplitude of the change of the fresh groundwater lens thickness and the volume depletion of the lens in oceanic island with sea-level rise, and on the other hand, the shortening of time required for groundwater to discharge into the ocean. These consequences can now be quantified and may help decision-makers to anticipate the effects of sea-level rise on fresh groundwater availability in oceanic island aquifers.

Three Dimensional Architecture of Membrane-Embedded MscS in the Closed Conformation

PubMed Central

Vásquez, Valeria; Sotomayor, Marcos; Cortes, D. Marien; Roux, Benoît; Schulten, Klaus; Perozo, Eduardo

2009-01-01

The mechanosensitive channel of small conductance (MscS) is part of a coordinated response to osmotic challenges in E. coli. MscS opens as a result of membrane tension changes, thereby releasing small solutes and effectively acting as an osmotic safety valve. Both, the functional state depicted by its crystal structure and its gating mechanism remain unclear. Here, we combine site-directed spin labeling, electron paramagnetic resonance (EPR) spectroscopy, and molecular dynamics simulations with novel energy restraints based on experimental EPR data to investigate the native transmembrane and periplasmic molecular architecture of closed MscS in a lipid bilayer. In the closed conformation, MscS shows a more compact transmembrane domain than in the crystal structure, characterized by a realignment of the transmembrane segments towards the normal of the membrane. The previously unresolved NH2-terminus forms a short helical hairpin capping the extracellular ends of TM1 and TM2 and in close interaction with the bilayer interface. The present three-dimensional model of membrane-embedded MscS in the closed state represents a key step in determining the molecular mechanism of MscS gating. PMID:18343404

Squashed Toric Sigma Models and Mock Modular Forms

NASA Astrophysics Data System (ADS)

Gupta, Rajesh Kumar; Murthy, Sameer

2018-05-01

We study a class of two-dimensional N}=(2,2)} sigma models called squashed toric sigma models, using their Gauged Linear Sigma Models (GLSM) description. These models are obtained by gauging the global {U(1)} symmetries of toric GLSMs and introducing a set of corresponding compensator superfields. The geometry of the resulting vacuum manifold is a deformation of the corresponding toric manifold in which the torus fibration maintains a constant size in the interior of the manifold, thus producing a neck-like region. We compute the elliptic genus of these models, using localization, in the case when the unsquashed vacuum manifolds obey the Calabi-Yau condition. The elliptic genera have a non-holomorphic dependence on the modular parameter {τ} coming from the continuum produced by the neck. In the simplest case corresponding to squashed {C / Z_{2 the elliptic genus is a mixed mock Jacobi form which coincides with the elliptic genus of the {N=(2,2)} {SL(2,R) / U(1)} cigar coset.

13 CFR 120.194 - Use of computer forms.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 13 Business Credit and Assistance 1 2014-01-01 2014-01-01 false Use of computer forms. 120.194... Applying to All Business Loans Computerized Sba Forms § 120.194 Use of computer forms. Any Applicant or Participant may use computer generated SBA application forms, closing forms, and other forms designated by SBA...

13 CFR 120.194 - Use of computer forms.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 13 Business Credit and Assistance 1 2012-01-01 2012-01-01 false Use of computer forms. 120.194... Applying to All Business Loans Computerized Sba Forms § 120.194 Use of computer forms. Any Applicant or Participant may use computer generated SBA application forms, closing forms, and other forms designated by SBA...

13 CFR 120.194 - Use of computer forms.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 13 Business Credit and Assistance 1 2013-01-01 2013-01-01 false Use of computer forms. 120.194... Applying to All Business Loans Computerized Sba Forms § 120.194 Use of computer forms. Any Applicant or Participant may use computer generated SBA application forms, closing forms, and other forms designated by SBA...

13 CFR 120.194 - Use of computer forms.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 13 Business Credit and Assistance 1 2011-01-01 2011-01-01 false Use of computer forms. 120.194... Applying to All Business Loans Computerized Sba Forms § 120.194 Use of computer forms. Any Applicant or Participant may use computer generated SBA application forms, closing forms, and other forms designated by SBA...

13 CFR 120.194 - Use of computer forms.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Use of computer forms. 120.194... Applying to All Business Loans Computerized Sba Forms § 120.194 Use of computer forms. Any Applicant or Participant may use computer generated SBA application forms, closing forms, and other forms designated by SBA...

On Closed Timelike Curves and Warped Brane World Models

NASA Astrophysics Data System (ADS)

Slagter, Reinoud Jan

2013-09-01

At first glance, it seems possible to construct in general relativity theory causality violating solutions. The most striking one is the Gott spacetime. Two cosmic strings, approaching each other with high velocity, could produce closed timelike curves. It was quickly recognized that this solution violates physical boundary conditions. The effective one particle generator becomes hyperbolic, so the center of mass is tachyonic. On a 5-dimensional warped spacetime, it seems possible to get an elliptic generator, so no obstruction is encountered and the velocity of the center of mass of the effective particle has an overlap with the Gott region. So a CTC could, in principle, be constructed. However, from the effective 4D field equations on the brane, which are influenced by the projection of the bulk Weyl tensor on the brane, it follows that no asymptotic conical space time is found, so no angle deficit as in the 4D counterpart model. This could also explain why we do not observe cosmic strings.

16 CFR Appendix C to Part 698 - Model Forms for Affiliate Marketing Opt-Out Notices

Code of Federal Regulations, 2012 CFR

2012-01-01

... Notices C Appendix C to Part 698 Commercial Practices FEDERAL TRADE COMMISSION THE FAIR CREDIT REPORTING ACT MODEL FORMS AND DISCLOSURES Pt. 698, App. C Appendix C to Part 698—Model Forms for Affiliate... of opt-outs by joint consumers to comply with § 680.23(a)(2) of part 680. C-1 Model Form for Initial...

16 CFR Appendix C to Part 698 - Model Forms for Affiliate Marketing Opt-Out Notices

Code of Federal Regulations, 2014 CFR

2014-01-01

... Notices C Appendix C to Part 698 Commercial Practices FEDERAL TRADE COMMISSION THE FAIR CREDIT REPORTING ACT MODEL FORMS AND DISCLOSURES Pt. 698, App. C Appendix C to Part 698—Model Forms for Affiliate... of opt-outs by joint consumers to comply with § 680.23(a)(2) of part 680. C-1 Model Form for Initial...

16 CFR Appendix C to Part 698 - Model Forms for Affiliate Marketing Opt-Out Notices

Code of Federal Regulations, 2013 CFR

2013-01-01

... Notices C Appendix C to Part 698 Commercial Practices FEDERAL TRADE COMMISSION THE FAIR CREDIT REPORTING ACT MODEL FORMS AND DISCLOSURES Pt. 698, App. C Appendix C to Part 698—Model Forms for Affiliate... of opt-outs by joint consumers to comply with § 680.23(a)(2) of part 680. C-1 Model Form for Initial...

Orbital stability close to asteroid 624 Hektor using the polyhedral model

NASA Astrophysics Data System (ADS)

Jiang, Yu; Baoyin, Hexi; Li, Hengnian

2018-03-01

We investigate the orbital stability close to the unique L4-point Jupiter binary Trojan asteroid 624 Hektor. The gravitational potential of 624 Hektor is calculated using the polyhedron model with observational data of 2038 faces and 1021 vertexes. Previous studies have presented three different density values for 624 Hektor. The equilibrium points in the gravitational potential of 624 Hektor with different density values have been studied in detail. There are five equilibrium points in the gravitational potential of 624 Hektor no matter the density value. The positions, Jacobian, eigenvalues, topological cases, stability, as well as the Hessian matrix of the equilibrium points are investigated. For the three different density values the number, topological cases, and the stability of the equilibrium points with different density values are the same. However, the positions of the equilibrium points vary with the density value of the asteroid 624 Hektor. The outer equilibrium points move away from the asteroid's mass center when the density increases, and the inner equilibrium point moves close to the asteroid's mass center when the density increases. There exist unstable periodic orbits near the surface of 624 Hektor. We calculated an orbit near the primary's equatorial plane of this binary Trojan asteroid; the results indicate that the orbit remains stable after 28.8375 d.

Structures of closed and open states of a voltage-gated sodium channel

PubMed Central

Lenaeus, Michael J.; Gamal El-Din, Tamer M.; Ramanadane, Karthik; Pomès, Régis; Zheng, Ning; Catterall, William A.

2017-01-01

Bacterial voltage-gated sodium channels (BacNavs) serve as models of their vertebrate counterparts. BacNavs contain conserved voltage-sensing and pore-forming domains, but they are homotetramers of four identical subunits, rather than pseudotetramers of four homologous domains. Here, we present structures of two NaVAb mutants that capture tightly closed and open states at a resolution of 2.8–3.2 Å. Introduction of two humanizing mutations in the S6 segment (NaVAb/FY: T206F and V213Y) generates a persistently closed form of the activation gate in which the intracellular ends of the four S6 segments are drawn tightly together to block ion permeation completely. This construct also revealed the complete structure of the four-helix bundle that forms the C-terminal domain. In contrast, truncation of the C-terminal 40 residues in NavAb/1–226 captures the activation gate in an open conformation, revealing the open state of a BacNav with intact voltage sensors. Comparing these structures illustrates the full range of motion of the activation gate, from closed with its orifice fully occluded to open with an orifice of ∼10 Å. Molecular dynamics and free-energy simulations confirm designation of NaVAb/1–226 as an open state that allows permeation of hydrated Na+, and these results also support a hydrophobic gating mechanism for control of ion permeation. These two structures allow completion of a closed–open–inactivated conformational cycle in a single voltage-gated sodium channel and give insight into the structural basis for state-dependent binding of sodium channel-blocking drugs. PMID:28348242

Atmosphere Expansion and Mass Loss of Close-orbit Giant Exoplanets Heated by Stellar XUV. I. Modeling of Hydrodynamic Escape of Upper Atmospheric Material

NASA Astrophysics Data System (ADS)

Shaikhislamov, I. F.; Khodachenko, M. L.; Sasunov, Yu. L.; Lammer, H.; Kislyakova, K. G.; Erkaev, N. V.

2014-11-01

In the present series of papers we propose a consistent description of the mass loss process. To study in a comprehensive way the effects of the intrinsic magnetic field of a close-orbit giant exoplanet (a so-called hot Jupiter) on atmospheric material escape and the formation of a planetary inner magnetosphere, we start with a hydrodynamic model of an upper atmosphere expansion in this paper. While considering a simple hydrogen atmosphere model, we focus on the self-consistent inclusion of the effects of radiative heating and ionization of the atmospheric gas with its consequent expansion in the outer space. Primary attention is paid to an investigation of the role of the specific conditions at the inner and outer boundaries of the simulation domain, under which different regimes of material escape (free and restricted flow) are formed. A comparative study is performed of different processes, such as X-ray and ultraviolet (XUV) heating, material ionization and recombination, H_3^ + cooling, adiabatic and Lyα cooling, and Lyα reabsorption. We confirm the basic consistency of the outcomes of our modeling with the results of other hydrodynamic models of expanding planetary atmospheres. In particular, we determine that, under the typical conditions of an orbital distance of 0.05 AU around a Sun-type star, a hot Jupiter plasma envelope may reach maximum temperatures up to ~9000 K with a hydrodynamic escape speed of ~9 km s-1, resulting in mass loss rates of ~(4-7) · 1010 g s-1. In the range of the considered stellar-planetary parameters and XUV fluxes, that is close to the mass loss in the energy-limited case. The inclusion of planetary intrinsic magnetic fields in the model is a subject of the follow-up paper (Paper II).

Closed Loop System Identification with Genetic Algorithms

NASA Technical Reports Server (NTRS)

Whorton, Mark S.

2004-01-01

High performance control design for a flexible space structure is challenging since high fidelity plant models are di.cult to obtain a priori. Uncertainty in the control design models typically require a very robust, low performance control design which must be tuned on-orbit to achieve the required performance. Closed loop system identi.cation is often required to obtain a multivariable open loop plant model based on closed-loop response data. In order to provide an accurate initial plant model to guarantee convergence for standard local optimization methods, this paper presents a global parameter optimization method using genetic algorithms. A minimal representation of the state space dynamics is employed to mitigate the non-uniqueness and over-parameterization of general state space realizations. This control-relevant system identi.cation procedure stresses the joint nature of the system identi.cation and control design problem by seeking to obtain a model that minimizes the di.erence between the predicted and actual closed-loop performance.

Simple equations to simulate closed-loop recycling liquid-liquid chromatography: Ideal and non-ideal recycling models.

PubMed

Kostanyan, Artak E

2015-12-04

The ideal (the column outlet is directly connected to the column inlet) and non-ideal (includes the effects of extra-column dispersion) recycling equilibrium-cell models are used to simulate closed-loop recycling counter-current chromatography (CLR CCC). Simple chromatogram equations for the individual cycles and equations describing the transport and broadening of single peaks and complex chromatograms inside the recycling closed-loop column for ideal and non-ideal recycling models are presented. The extra-column dispersion is included in the theoretical analysis, by replacing the recycling system (connecting lines, pump and valving) by a cascade of Nec perfectly mixed cells. To evaluate extra-column contribution to band broadening, two limiting regimes of recycling are analyzed: plug-flow, Nec→∞, and maximum extra-column dispersion, Nec=1. Comparative analysis of ideal and non-ideal models has shown that when the volume of the recycling system is less than one percent of the column volume, the influence of the extra-column processes on the CLR CCC separation may be neglected. Copyright © 2015 Elsevier B.V. All rights reserved.

Close-up analysis of aircraft ice accretion

NASA Technical Reports Server (NTRS)

Hansman, R. John; Breuer, Kenneth S.; Hazan, Didier; Reehorst, Andrew; Vargas, Mario

1993-01-01

Various types of ice formation have been studied by analysis of high magnification video observations. All testing was conducted in the NASA Lewis Icing Research Tunnel (IRT). A faired 8.9 cm (3.5 in.) diameter metal-clad cylinder and a 5.1 (2 in.) aluminum cylinder were observed by close-up and overview video cameras for several wind tunnel conditions. These included close-up grazing angle, close-up side view, as well as overhead and side overview cameras. Still photographs were taken at the end of each spray along with tracings of the subsequent ice shape. While in earlier tests only the stagnation region was observed, the entire area from the stagnation line to the horn region of glaze ice shapes was observed in this test. The modes or horn formation have been identified within the range of conditions observed. In the horn region, Horn Type A ice is formed by 'dry' feather growth into the flow direction and Horn Type B is formed by a 'wet' growth normal to the surface. The feather growth occurs when the freezing fraction is near unity and roughness elements exist to provide an initial growth site.

Apoptosis generates mechanical forces that close the lens vesicle in the chick embryo

NASA Astrophysics Data System (ADS)

Oltean, Alina; Taber, Larry A.

2018-03-01

During the initial stages of eye development, optic vesicles grow laterally outward from both sides of the forebrain and come into contact with the surrounding surface ectoderm (SE). Within the region of contact, these layers then thicken locally to create placodes and invaginate to form the optic cup (primitive retina) and lens vesicle (LV), respectively. This paper examines the biophysical mechanisms involved in LV formation, which consists of three phases: (1) lens placode formation; (2) invagination to create the lens pit (LP); and (3) closure to form a complete ellipsoidally shaped LV. Previous studies have suggested that extracellular matrix deposited between the SE and optic vesicle causes the lens placode to form by locally constraining expansion of the SE as it grows, while actomyosin contraction causes this structure to invaginate. Here, using computational modeling and experiments on chick embryos, we confirm that these mechanisms for Phases 1 and 2 are physically plausible. Our results also suggest, however, that they are not sufficient to close the LP during Phase 3. We postulate that apoptosis provides an additional mechanism by removing cells near the LP opening, thereby decreasing its circumference and generating tension that closes the LP. This hypothesis is supported by staining that shows a ring of cell death located around the LP opening during closure. Inhibiting apoptosis in cultured embryos using caspase inhibitors significantly reduced LP closure, and results from a finite-element model indicate that closure driven by cell death is plausible. Taken together, our results suggest an important mechanical role for apoptosis in lens development.

Modeling the Spray Forming of H13 Steel Tooling

NASA Astrophysics Data System (ADS)

Lin, Yaojun; McHugh, Kevin M.; Zhou, Yizhang; Lavernia, Enrique J.

2007-07-01

On the basis of a numerical model, the temperature and liquid fraction of spray-formed H13 tool steel are calculated as a function of time. Results show that a preheated substrate at the appropriate temperature can lead to very low porosity by increasing the liquid fraction in the deposited steel. The calculated cooling rate can lead to a microstructure consisting of martensite, lower bainite, retained austenite, and proeutectoid carbides in as-spray-formed material. In the temperature range between the solidus and liquidus temperatures, the calculated temperature of the spray-formed material increases with increasing substrate preheat temperature, resulting in a very low porosity by increasing the liquid fraction of the deposited steel. In the temperature region where austenite decomposition occurs, the substrate preheat temperature has a negligible influence on the cooling rate of the spray-formed material. On the basis of the calculated results, it is possible to generate sufficient liquid fraction during spray forming by using a high growth rate of the deposit without preheating the substrate, and the growth rate of the deposit has almost no influence on the cooling rate in the temperature region of austenite decomposition.

Model Checking Techniques for Assessing Functional Form Specifications in Censored Linear Regression Models.

PubMed

León, Larry F; Cai, Tianxi

2012-04-01

In this paper we develop model checking techniques for assessing functional form specifications of covariates in censored linear regression models. These procedures are based on a censored data analog to taking cumulative sums of "robust" residuals over the space of the covariate under investigation. These cumulative sums are formed by integrating certain Kaplan-Meier estimators and may be viewed as "robust" censored data analogs to the processes considered by Lin, Wei & Ying (2002). The null distributions of these stochastic processes can be approximated by the distributions of certain zero-mean Gaussian processes whose realizations can be generated by computer simulation. Each observed process can then be graphically compared with a few realizations from the Gaussian process. We also develop formal test statistics for numerical comparison. Such comparisons enable one to assess objectively whether an apparent trend seen in a residual plot reects model misspecification or natural variation. We illustrate the methods with a well known dataset. In addition, we examine the finite sample performance of the proposed test statistics in simulation experiments. In our simulation experiments, the proposed test statistics have good power of detecting misspecification while at the same time controlling the size of the test.

The Evaluation Of Therapeutic Efficacy and Safety Profile of Simvastatin Prodrug Micelles in a Closed Fracture Mouse Model

PubMed Central

Zhang, Yijia; Jia, Zhenshan; Yuan, Hongjiang; Dusad, Anand; Ren, Ke; Wei, Xin; Fehringer, Edward V.; Purdue, P. Edward; Daluiski, Aaron; Goldring, Steven R.; Wang, Dong

2016-01-01

Purpose To evaluate the therapeutic efficiency of a micellar prodrug formulation of simvastatin (SIM/SIM-mPEG) and explore its safety in a closed femoral fracture mouse model. Methods The amphiphilic macromolecular prodrug of simvastatin (SIM-mPEG) was synthesized and formulated together with free simvastatin into micelles. It was also labeled with a near infrared dye for in vivo imaging purpose. A closed femoral fracture mouse model was established using a three-point bending device. The mice with established closed femoral fracture were treated with SIM/SIM-mPEG micelle, using free simvastatin and saline as controls. The therapeutic efficacy of the micelles was evaluated using a high-resolution micro-CT. Serum biochemistry and histology analyses were performed to explore the potential toxicity of the micelle formulation. Results Near Infrared Fluorescence (NIRF) imaging confirmed the passive targeting of SIM/SIM-mPEG micelles to the bone lesion of the mice with closed femoral fracture. The micelle was found to promote fracture healing with an excellent safety profile. In addition, the accelerated healing of the femoral fracture also helped to prevent disuse-associated same-side tibia bone loss accompanying the femur fracture. Conclusion SIM/SIM-mPEG micelle was found to be an effective and safe treatment for closed femoral fracture repair in mice. The evidence obtained in this study suggests that it may have the potential to be translated into a novel therapy for clinical management of skeletal fractures and non-union. PMID:27164897

Closing the contrast gap between testbed and model prediction with WFIRST-CGI shaped pupil coronagraph

NASA Astrophysics Data System (ADS)

Zhou, Hanying; Nemati, Bijan; Krist, John; Cady, Eric; Prada, Camilo M.; Kern, Brian; Poberezhskiy, Ilya

2016-07-01

JPL has recently passed an important milestone in its technology development for a proposed NASA WFIRST mission coronagraph: demonstration of better than 1x10-8 contrast over broad bandwidth (10%) on both shaped pupil coronagraph (SPC) and hybrid Lyot coronagraph (HLC) testbeds with the WFIRST obscuration pattern. Challenges remain, however, in the technology readiness for the proposed mission. One is the discrepancies between the achieved contrasts on the testbeds and their corresponding model predictions. A series of testbed diagnoses and modeling activities were planned and carried out on the SPC testbed in order to close the gap. A very useful tool we developed was a derived "measured" testbed wavefront control Jacobian matrix that could be compared with the model-predicted "control" version that was used to generate the high contrast dark hole region in the image plane. The difference between these two is an estimate of the error in the control Jacobian. When the control matrix, which includes both amplitude and phase, was modified to reproduce the error, the simulated performance closely matched the SPC testbed behavior in both contrast floor and contrast convergence speed. This is a step closer toward model validation for high contrast coronagraphs. Further Jacobian analysis and modeling provided clues to the possible sources for the mismatch: DM misregistration and testbed optical wavefront error (WFE) and the deformable mirror (DM) setting for correcting this WFE. These analyses suggested that a high contrast coronagraph has a tight tolerance in the accuracy of its control Jacobian. Modifications to both testbed control model as well as prediction model are being implemented, and future works are discussed.

QSAR models for removal rates of organic pollutants adsorbed by in situ formed manganese dioxide under acid condition.

PubMed

Su, Pingru; Zhu, Huicen; Shen, Zhemin

2016-02-01

Manganese dioxide formed in oxidation process by potassium permanganate exhibits promising adsorptive capacity which can be utilized to remove organic pollutants in wastewater. However, the structure variances of organic molecules lead to wide difference of adsorption efficiency. Therefore, it is of great significance to find a general relationship between removal rate of organic compounds and their quantum parameters. This study focused on building up quantitative structure activity relationship (QSAR) models based on experimental removal rate (r(exp)) of 25 organic compounds and 17 quantum parameters of each organic compounds computed by Gaussian 09 and Material Studio 6.1. The recommended model is rpre = -0.502-7.742 f(+)x + 0.107 E HOMO + 0.959 q(H(+)) + 1.388 BOx. Both internal and external validations of the recommended model are satisfied, suggesting optimum stability and predictive ability. The definition of applicability domain and the Y-randomization test indicate all the prediction is reliable and no possibility of chance correlation. The recommended model contains four variables, which are closely related to adsorption mechanism. f(+)x reveals the degree of affinity for nucleophilic attack. E HOMO represents the difficulty of electron loss. q(H(+)) reflect the distribution of partial charge between carbon and hydrogen atom. BO x shows the stability of a molecule.

Model-independent and fast determination of optical functions in storage rings via multiturn and closed-orbit data

NASA Astrophysics Data System (ADS)

Riemann, Bernard; Grete, Patrick; Weis, Thomas

2011-06-01

Multiturn (or turn-by-turn) data acquisition has proven to be a new source of direct measurements for Twiss parameters in storage rings. On the other hand, closed-orbit measurements are a long-known tool for analyzing closed-orbit perturbations with conventional beam position monitor (BPM) systems and are necessarily available at every storage ring. This paper aims at combining the advantages of multiturn measurements and closed-orbit data. We show that only two multiturn BPMs and four correctors in one localized drift space in the storage ring (diagnostic drift) are sufficient for model-independent and absolute measuring of β and φ functions at all BPMs, including the conventional ones, instead of requiring all BPMs being equipped with multiturn electronics.

Terrestrial Planet Formation Around Close Binary Stars

NASA Technical Reports Server (NTRS)

Lissauer, Jack J.; Quintana, Elisa V.

2003-01-01

Most stars reside in multiple star systems; however, virtually all models of planetary growth have assumed an isolated single star. Numerical simulations of the collapse of molecular cloud cores to form binary stars suggest that disks will form within such systems. Observations indirectly suggest disk material around one or both components within young binary star systems. If planets form at the right places within such circumstellar disks, they can remain in stable orbits within the binary star systems for eons. We are simulating the late stages of growth of terrestrial planets around close binary stars, using a new, ultrafast, symplectic integrator that we have developed for this purpose. The sum of the masses of the two stars is one solar mass, and the initial disk of planetary embryos is the same as that used for simulating the late stages of terrestrial planet growth within our Solar System and in the Alpha Centauri wide binary star system. Giant planets &are included in the simulations, as they are in most simulations of the late stages of terrestrial planet accumulation in our Solar System. When the stars travel on a circular orbit with semimajor axis of up to 0.1 AU about their mutual center of mass, the planetary embryos grow into a system of terrestrial planets that is statistically identical to those formed about single stars, but a larger semimajor axis and/or a significantly eccentric binary orbit can lead to significantly more dynamically hot terrestrial planet systems.

Closed Brayton cycle power conversion systems for nuclear reactors :

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wright, Steven A.; Lipinski, Ronald J.; Vernon, Milton E.

2006-04-01

This report describes the results of a Sandia National Laboratories internally funded research program to study the coupling of nuclear reactors to gas dynamic Brayton power conversion systems. The research focused on developing integrated dynamic system models, fabricating a 10-30 kWe closed loop Brayton cycle, and validating these models by operating the Brayton test-loop. The work tasks were performed in three major areas. First, the system equations and dynamic models for reactors and Closed Brayton Cycle (CBC) systems were developed and implemented in SIMULINKTM. Within this effort, both steady state and dynamic system models for all the components (turbines, compressors,more » reactors, ducting, alternators, heat exchangers, and space based radiators) were developed and assembled into complete systems for gas cooled reactors, liquid metal reactors, and electrically heated simulators. Various control modules that use proportional-integral-differential (PID) feedback loops for the reactor and the power-conversion shaft speed were also developed and implemented. The simulation code is called RPCSIM (Reactor Power and Control Simulator). In the second task an open cycle commercially available Capstone C30 micro-turbine power generator was modified to provide a small inexpensive closed Brayton cycle test loop called the Sandia Brayton test-Loop (SBL-30). The Capstone gas-turbine unit housing was modified to permit the attachment of an electrical heater and a water cooled chiller to form a closed loop. The Capstone turbine, compressor, and alternator were used without modification. The Capstone systems nominal operating point is 1150 K turbine inlet temperature at 96,000 rpm. The annular recuperator and portions of the Capstone control system (inverter) and starter system also were reused. The rotational speed of the turbo-machinery is controlled by adjusting the alternator load by using the electrical grid as the load bank. The SBL-30 test loop was operated at

Demonstration of close-coupled barriers for subsurface containment of buried waste

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dwyer, B.P.

1996-05-01

A close-coupled barrier is produced by first installing a conventional cement grout curtain followed by a thin inner lining of a polymer grout. The resultant barrier is a cement polymer composite that has economic benefits derived from the cement and performance benefits from the durable and resistant polymer layer. Close-coupled barrier technology is applicable for final, interim, or emergency containment of subsurface waste forms. Consequently, when considering the diversity of technology application, the construction emplacement and material technology maturity, general site operational requirements, and regulatory compliance incentives, the close-coupled barrier system provides an alternative for any hazardous or mixed wastemore » remediation plan. This paper discusses the installation of a close-coupled barrier and the subsequent integrity verification. The demonstration was installed at a benign site at the Hanford Geotechnical Test Facility, 400 Area, Hanford, Washington. The composite barrier was emplaced beneath a 7,500 liter tank. The tank was chosen to simulate a typical DOE Complex waste form. The stresses induced on the waste form were evaluated during barrier construction. The barrier was constructed using conventional jet grouting techniques. Drilling was completed at a 45{degree} angle to the ground, forming a conical shaped barrier with the waste form inside the cone. Two overlapping rows of cylindrical cement columns were grouted in a honeycomb fashion to form the secondary backdrop barrier layer. The primary barrier, a high molecular weight polymer manufactured by 3M Company, was then installed providing a relatively thin inner liner for the secondary barrier. The primary barrier was emplaced by panel jet grouting with a dual wall drill stem, two phase jet grouting system.« less

12 CFR Appendix C to Part 1022 - Model Forms for Opt-Out Notices

Code of Federal Regulations, 2014 CFR

2014-01-01

...-Affiliate Notice) C-4Model Form for Renewal Notice (Joint Notice) C-5Model Form for Voluntary “No Marketing... Marketing]/[Marketing Opt-Out] • [Name of Affiliate] is providing this notice. • [Optional: Federal law gives you the right to limit some but not all marketing from our affiliates. Federal law also requires...

Electrochemical Corrosion Studies for Modeling Metallic Waste Form Release Rates

DOE Office of Scientific and Technical Information (OSTI.GOV)

Poineau, Frederic; Tamalis, Dimitri

The isotope 99Tc is an important fission product generated from nuclear power production. Because of its long half-life (t 1/2 = 2.13 ∙ 10 5 years) and beta-radiotoxicity (β⁻ = 292 keV), it is a major concern in the long-term management of spent nuclear fuel. In the spent nuclear fuel, Tc is present as an alloy with Mo, Ru, Rh, and Pd called the epsilon-phase, the relative amount of which increases with fuel burn-up. In some separation schemes for spent nuclear fuel, Tc would be separated from the spent fuel and disposed of in a durable waste form. Technetium wastemore » forms under consideration include metallic alloys, oxide ceramics and borosilicate glass. In the development of a metallic waste form, after separation from the spent fuel, Tc would be converted to the metal, incorporated into an alloy and the resulting waste form stored in a repository. Metallic alloys under consideration include Tc–Zr alloys, Tc–stainless steel alloys and Tc–Inconel alloys (Inconel is an alloy of Ni, Cr and iron which is resistant to corrosion). To predict the long-term behavior of the metallic Tc waste form, understanding the corrosion properties of Tc metal and Tc alloys in various chemical environments is needed, but efforts to model the behavior of Tc metallic alloys are limited. One parameter that should also be considered in predicting the long-term behavior of the Tc waste form is the ingrowth of stable Ru that occurs from the radioactive decay of 99Tc ( 99Tc → 99Ru + β⁻). After a geological period of time, significant amounts of Ru will be present in the Tc and may affect its corrosion properties. Studying the effect of Ru on the corrosion behavior of Tc is also of importance. In this context, we studied the electrochemical behavior of Tc metal, Tc-Ni alloys (to model Tc-Inconel alloy) and Tc-Ru alloys in acidic media. The study of Tc-U alloys has also been performed in order to better understand the nature of Tc in metallic spent fuel. Computational

Implementation of virtual models from sheet metal forming simulation into physical 3D colour models using 3D printing

NASA Astrophysics Data System (ADS)

Junk, S.

2016-08-01

Today the methods of numerical simulation of sheet metal forming offer a great diversity of possibilities for optimization in product development and in process design. However, the results from simulation are only available as virtual models. Because there are any forming tools available during the early stages of product development, physical models that could serve to represent the virtual results are therefore lacking. Physical 3D-models can be created using 3D-printing and serve as an illustration and present a better understanding of the simulation results. In this way, the results from the simulation can be made more “comprehensible” within a development team. This paper presents the possibilities of 3D-colour printing with particular consideration of the requirements regarding the implementation of sheet metal forming simulation. Using concrete examples of sheet metal forming, the manufacturing of 3D colour models will be expounded upon on the basis of simulation results.

Genome-Wide Analysis of Gene-Gene and Gene-Environment Interactions Using Closed-Form Wald Tests.

PubMed

Yu, Zhaoxia; Demetriou, Michael; Gillen, Daniel L

2015-09-01

Despite the successful discovery of hundreds of variants for complex human traits using genome-wide association studies, the degree to which genes and environmental risk factors jointly affect disease risk is largely unknown. One obstacle toward this goal is that the computational effort required for testing gene-gene and gene-environment interactions is enormous. As a result, numerous computationally efficient tests were recently proposed. However, the validity of these methods often relies on unrealistic assumptions such as additive main effects, main effects at only one variable, no linkage disequilibrium between the two single-nucleotide polymorphisms (SNPs) in a pair or gene-environment independence. Here, we derive closed-form and consistent estimates for interaction parameters and propose to use Wald tests for testing interactions. The Wald tests are asymptotically equivalent to the likelihood ratio tests (LRTs), largely considered to be the gold standard tests but generally too computationally demanding for genome-wide interaction analysis. Simulation studies show that the proposed Wald tests have very similar performances with the LRTs but are much more computationally efficient. Applying the proposed tests to a genome-wide study of multiple sclerosis, we identify interactions within the major histocompatibility complex region. In this application, we find that (1) focusing on pairs where both SNPs are marginally significant leads to more significant interactions when compared to focusing on pairs where at least one SNP is marginally significant; and (2) parsimonious parameterization of interaction effects might decrease, rather than increase, statistical power. © 2015 WILEY PERIODICALS, INC.

Quantitative model of super-Arrhenian behavior in glass forming materials

NASA Astrophysics Data System (ADS)

Caruthers, J. M.; Medvedev, G. A.

2018-05-01

The key feature of glass forming liquids is the super-Arrhenian temperature dependence of the mobility, where the mobility can increase by ten orders of magnitude or more as the temperature is decreased if crystallization does not intervene. A fundamental description of the super-Arrhenian behavior has been developed; specifically, the logarithm of the relaxation time is a linear function of 1 /U¯x , where U¯x is the independently determined excess molar internal energy and B is a material constant. This one-parameter mobility model quantitatively describes data for 21 glass forming materials, which are all the materials where there are sufficient experimental data for analysis. The effect of pressure on the loga mobility is also described using the same U¯x(T ,p ) function determined from the difference between the liquid and crystalline internal energies. It is also shown that B is well correlated with the heat of fusion. The prediction of the B /U¯x model is compared to the Adam and Gibbs 1 /T S¯x model, where the B /U¯x model is significantly better in unifying the full complement of mobility data. The implications of the B /U¯x model for the development of a fundamental description of glass are discussed.

An introductory characterization of a combat-casualty-care relevant swine model of closed head injury resulting from exposure to explosive blast.

PubMed

Bauman, Richard A; Ling, Geoffrey; Tong, Lawrence; Januszkiewicz, Adolph; Agoston, Dennis; Delanerolle, Nihal; Kim, Young; Ritzel, Dave; Bell, Randy; Ecklund, James; Armonda, Rocco; Bandak, Faris; Parks, Steven

2009-06-01

Explosive blast has been extensively used as a tactical weapon in Operation Iraqi Freedom (OIF) and more recently in Operation Enduring Freedom(OEF). The polytraumatic nature of blast injuries is evidence of their effectiveness,and brain injury is a frequent and debilitating form of this trauma. In-theater clinical observations of brain-injured casualties have shown that edema, intracranial hemorrhage, and vasospasm are the most salient pathophysiological characteristics of blast injury to the brain. Unfortunately, little is known about exactly how an explosion produces these sequelae as well as others that are less well documented. Consequently, the principal objective of the current report is to present a swine model of explosive blast injury to the brain. This model was developed during Phase I of the DARPA (Defense Advanced Research Projects Agency) PREVENT (Preventing Violent Explosive Neurotrauma) blast research program. A second objective is to present data that illustrate the capabilities of this model to study the proximal biomechanical causes and the resulting pathophysiological, biochemical,neuropathological, and neurological consequences of explosive blast injury to the swine brain. In the concluding section of this article, the advantages and limitations of the model are considered, explosive and air-overpressure models are compared, and the physical properties of an explosion are identified that potentially contributed to the in-theater closed head injuries resulting from explosions of improvised explosive devices (IEDs).

Modeling Closed Equilibrium Systems of H2O-Dissolved CO2-Solid CaCO3.

PubMed

Tenno, Toomas; Uiga, Kalev; Mashirin, Alexsey; Zekker, Ivar; Rikmann, Ergo

2017-04-27

In many places in the world, including North Estonia, the bedrock is limestone, which consists mainly of CaCO 3 . Equilibrium processes in water involving dissolved CO 2 and solid CaCO 3 play a vital role in many biological and technological systems. The solubility of CaCO 3 in water is relatively low. Depending on the concentration of dissolved CO 2 , the solubility of CaCO 3 changes, which determines several important ground- and wastewater parameters, for example, Ca 2+ concentration and pH. The distribution of ions and molecules in the closed system solid H 2 O-dissolved CO 2 -solid CaCO 3 is described in terms of a structural scheme. Mathematical models were developed for the calculation of pH and concentrations of ions and molecules (Ca 2+ , CO 3 2- , HCO 3 - , H 2 CO 3 , CO 2 , H + , and OH - ) in the closed equilibrium system at different initial concentrations of CO 2 in the water phase using an iteration method. The developed models were then experimentally validated.

Modeling and FE Simulation of Quenchable High Strength Steels Sheet Metal Hot Forming Process

NASA Astrophysics Data System (ADS)

Liu, Hongsheng; Bao, Jun; Xing, Zhongwen; Zhang, Dejin; Song, Baoyu; Lei, Chengxi

2011-08-01

High strength steel (HSS) sheet metal hot forming process is investigated by means of numerical simulations. With regard to a reliable numerical process design, the knowledge of the thermal and thermo-mechanical properties is essential. In this article, tensile tests are performed to examine the flow stress of the material HSS 22MnB5 at different strains, strain rates, and temperatures. Constitutive model based on phenomenological approach is developed to describe the thermo-mechanical properties of the material 22MnB5 by fitting the experimental data. A 2D coupled thermo-mechanical finite element (FE) model is developed to simulate the HSS sheet metal hot forming process for U-channel part. The ABAQUS/explicit model is used conduct the hot forming stage simulations, and ABAQUS/implicit model is used for accurately predicting the springback which happens at the end of hot forming stage. Material modeling and FE numerical simulations are carried out to investigate the effect of the processing parameters on the hot forming process. The processing parameters have significant influence on the microstructure of U-channel part. The springback after hot forming stage is the main factor impairing the shape precision of hot-formed part. The mechanism of springback is advanced and verified through numerical simulations and tensile loading-unloading tests. Creep strain is found in the tensile loading-unloading test under isothermal condition and has a distinct effect on springback. According to the numerical and experimental results, it can be concluded that springback is mainly caused by different cooling rats and the nonhomogengeous shrink of material during hot forming process, the creep strain is the main factor influencing the amount of the springback.

Movement Forms: A Graph-Dynamic Perspective

PubMed Central

Saltzman, Elliot; Holt, Ken

2014-01-01

The focus of this paper is on characterizing the physical movement forms (e.g., walk, crawl, roll, etc.) that can be used to actualize abstract, functionally-specified behavioral goals (e.g., locomotion). Emphasis is placed on how such forms are distinguished from one another, in part, by the set of topological patterns of physical contact between agent and environment (i.e., the set of physical graphs associated with each form) and the transitions among these patterns displayed over the course of performance (i.e., the form’s physical graph dynamics). Crucial in this regard is the creation and dissolution of loops in these graphs, which can be related to the distinction between open and closed kinematic chains. Formal similarities are described within the theoretical framework of task-dynamics between physically-closed kinematic chains (physical loops) that are created during various movement forms and functionally-closed kinematic chains (functional loops) that are associated with task-space control of end-effectors; it is argued that both types of loop must be flexibly incorporated into the coordinative structures that govern skilled action. Final speculation is focused on the role of graphs and their dynamics, not only in processes of coordination and control for individual agents, but also in processes of inter-agent coordination and the coupling of agents with (non-sentient) environmental objects. PMID:24910507

Lunar Tire Close-up

NASA Image and Video Library

2017-02-23

This is a close-up of an exact replica of the Apollo-era Lunar Roving Vehicle Wheel, of which twelve originals still rest on the surface of the Moon. The tire was designed to flex under load, without air, and was formed from a mesh of plated piano wire. Metal straps were hand riveted onto the mesh to reduce sinking into loose lunar soils. These replica wheels were tested in NASA Glenn's SLOPE Lab to establish a baseline for future improvements.

Method of Forming a Hot Film Sensor System on a Model

NASA Technical Reports Server (NTRS)

Tran, Sang Q. (Inventor)

1998-01-01

A method of forming a hot film sensor directly on a model is provided. A polyimide solution is sprayed onto the model. The model so sprayed is then heated in air. The steps of spraying and heating are repeated until a polyimide film of desired thickness is achieved on the model. The model with the polyimide film thereon is then thoroughly dried in air. One or more hot film sensors and corresponding electrical conducting leads are then applied directly onto the polyimide film.

Use of the reciprocity theorem for a closed form solution of scattering of the lowest axially symmetric torsional wave mode by a defect in a pipe.

PubMed

Lee, Jaesun; Achenbach, Jan D; Cho, Younho

2018-03-01

Guided waves can effectively be used for inspection of large scale structures. Surface corrosion is often found as major defect type in large scale structures such as pipelines. Guided wave interaction with surface corrosion can provide useful information for sizing and classification. In this paper, the elastodynamic reciprocity theorem is used to formulate and solve complicated scattering problems in a simple manner. The approach has already been applied to scattering of Rayleigh and Lamb waves by defects to produce closed form solutions of amplitude of scattered waves. In this paper, the scattering of the lowest axially symmetric torsional mode, which is widely used in commercial applications, is analyzed by the reciprocity theorem. In the present paper, the theorem is used to determine the scattering of the lowest torsional mode by a tapered defect that was earlier considered experimentally and numerically by the finite element method. It is shown that by the presented method it is simple to obtain the ratio of amplitudes of scattered torsional modes for a tapered notch. The results show a good agreement with earlier numerical results. The wave field superposition technique in conjunction with the reciprocity theorem simplifies the solution of the scattering problem to yield a closed form solution which can play a significant role in quantitative signal interpretation. Copyright © 2017 Elsevier B.V. All rights reserved.

A Closed Network Queue Model of Underground Coal Mining Production, Failure, and Repair

NASA Technical Reports Server (NTRS)

Lohman, G. M.

1978-01-01

Underground coal mining system production, failures, and repair cycles were mathematically modeled as a closed network of two queues in series. The model was designed to better understand the technological constraints on availability of current underground mining systems, and to develop guidelines for estimating the availability of advanced mining systems and their associated needs for spares as well as production and maintenance personnel. It was found that: mine performance is theoretically limited by the maintainability ratio, significant gains in availability appear possible by means of small improvements in the time between failures the number of crews and sections should be properly balanced for any given maintainability ratio, and main haulage systems closest to the mine mouth require the most attention to reliability.

Similarity Metrics for Closed Loop Dynamic Systems

NASA Technical Reports Server (NTRS)

Whorton, Mark S.; Yang, Lee C.; Bedrossian, Naz; Hall, Robert A.

2008-01-01

To what extent and in what ways can two closed-loop dynamic systems be said to be "similar?" This question arises in a wide range of dynamic systems modeling and control system design applications. For example, bounds on error models are fundamental to the controller optimization with modern control design methods. Metrics such as the structured singular value are direct measures of the degree to which properties such as stability or performance are maintained in the presence of specified uncertainties or variations in the plant model. Similarly, controls-related areas such as system identification, model reduction, and experimental model validation employ measures of similarity between multiple realizations of a dynamic system. Each area has its tools and approaches, with each tool more or less suited for one application or the other. Similarity in the context of closed-loop model validation via flight test is subtly different from error measures in the typical controls oriented application. Whereas similarity in a robust control context relates to plant variation and the attendant affect on stability and performance, in this context similarity metrics are sought that assess the relevance of a dynamic system test for the purpose of validating the stability and performance of a "similar" dynamic system. Similarity in the context of system identification is much more relevant than are robust control analogies in that errors between one dynamic system (the test article) and another (the nominal "design" model) are sought for the purpose of bounding the validity of a model for control design and analysis. Yet system identification typically involves open-loop plant models which are independent of the control system (with the exception of limited developments in closed-loop system identification which is nonetheless focused on obtaining open-loop plant models from closed-loop data). Moreover the objectives of system identification are not the same as a flight test and

Inflation in the closed FLRW model and the CMB

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bonga, Béatrice; Gupt, Brajesh; Yokomizo, Nelson, E-mail: bpb165@psu.edu, E-mail: bgupt@gravity.psu.edu, E-mail: yokomizo@gravity.psu.edu

2016-10-01

Recent cosmic microwave background (CMB) observations put strong constraints on the spatial curvature via estimation of the parameter Ω{sub k} assuming an almost scale invariant primordial power spectrum. We study the evolution of the background geometry and gauge-invariant scalar perturbations in an inflationary closed FLRW model and calculate the primordial power spectrum. We find that the inflationary dynamics is modified due to the presence of spatial curvature, leading to corrections to the nearly scale invariant power spectrum at the end of inflation. When evolved to the surface of last scattering, the resulting temperature anisotropy spectrum ( C {sup TT}{sub ℓ})more » shows deficit of power at low multipoles (ℓ < 20). By comparing our results with the recent Planck data we discuss the role of spatial curvature in accounting for CMB anomalies and in the estimation of the parameter Ω{sub k}. Since the curvature effects are limited to low multipoles, the Planck estimation of cosmological parameters remains robust under inclusion of positive spatial curvature.« less

Various forms of indexing HDMR for modelling multivariate classification problems

DOE Office of Scientific and Technical Information (OSTI.GOV)

Aksu, Çağrı; Tunga, M. Alper

2014-12-10

The Indexing HDMR method was recently developed for modelling multivariate interpolation problems. The method uses the Plain HDMR philosophy in partitioning the given multivariate data set into less variate data sets and then constructing an analytical structure through these partitioned data sets to represent the given multidimensional problem. Indexing HDMR makes HDMR be applicable to classification problems having real world data. Mostly, we do not know all possible class values in the domain of the given problem, that is, we have a non-orthogonal data structure. However, Plain HDMR needs an orthogonal data structure in the given problem to be modelled.more » In this sense, the main idea of this work is to offer various forms of Indexing HDMR to successfully model these real life classification problems. To test these different forms, several well-known multivariate classification problems given in UCI Machine Learning Repository were used and it was observed that the accuracy results lie between 80% and 95% which are very satisfactory.« less

17 CFR Appendix to Subpart B of... - Model Forms

Code of Federal Regulations, 2014 CFR

2014-04-01

...) REGULATIONS S-P, S-AM, AND S-ID Regulation S-AM: Limitations on Affiliate Marketing Pt. 248, Subpt. B, App...—Model Form for Initial Opt Out Notice (Single-Affiliate Notice)—[Your Choice to Limit Marketing]/[Marketing Opt Out] • [Name of Affiliate] is providing this notice. • [Optional: Federal law gives you the...

17 CFR Appendix to Subpart B of... - Model Forms

Code of Federal Regulations, 2013 CFR

2013-04-01

...) REGULATIONS S-P AND S-AM Regulation S-AM: Limitations on Affiliate Marketing Pt. 248, Subpt. B, App. Appendix...—Model Form for Initial Opt Out Notice (Single-Affiliate Notice)—[Your Choice to Limit Marketing]/[Marketing Opt Out] • [Name of Affiliate] is providing this notice. • [Optional: Federal law gives you the...

17 CFR Appendix to Subpart B of... - Model Forms

Code of Federal Regulations, 2012 CFR

2012-04-01

...) REGULATIONS S-P AND S-AM Regulation S-AM: Limitations on Affiliate Marketing Pt. 248, Subpt. B, App. Appendix...—Model Form for Initial Opt Out Notice (Single-Affiliate Notice)—[Your Choice to Limit Marketing]/[Marketing Opt Out] • [Name of Affiliate] is providing this notice. • [Optional: Federal law gives you the...

17 CFR Appendix to Subpart B of... - Model Forms

Code of Federal Regulations, 2011 CFR

2011-04-01

...) REGULATIONS S-P AND S-AM Regulation S-AM: Limitations on Affiliate Marketing Pt. 248, Subpt. B, App. Appendix...—Model Form for Initial Opt Out Notice (Single-Affiliate Notice)—[Your Choice to Limit Marketing]/[Marketing Opt Out] • [Name of Affiliate] is providing this notice. • [Optional: Federal law gives you the...

In Situ Monitoring and Modeling of the Solution-Mediated Polymorphic Transformation of Rifampicin: From Form II to Form I.

PubMed

Guo, Nannan; Hou, Baohong; Wang, Na; Xiao, Yan; Huang, Jingjing; Guo, Yanmei; Zong, Shuyi; Hao, Hongxun

2018-01-01

In this article, the solution-mediated polymorphic transformation of rifampicin was investigated and simulated in 3 solvents at 30°C. The solid-state form I and form II of rifampicin was characterized by powder X-ray diffraction, scanning electron microscopy, thermogravimetric analysis, Raman spectroscopy, and Fourier transform infrared spectroscopy (FTIR). To explore the relative stability, solubility data of form I and form II of rifampicin in butan-1-ol were determined using a dynamical method. In addition, Raman spectroscopy and focused beam reflectance measurement were used to in situ monitor the transformation of rifampicin from form II to form I. The liquid state concentration of rifampicin was measured by UV spectroscopic method. To investigate the effect of solvent on transformation, the transformation experiments were carried out in 3 solvents. Furthermore, a mathematical model was built to describe the kinetics of dissolution, nucleation, and growth processes during transformation by using experimental data. By combination of experimental and simulation results, it was found that the transformation process of rifampicin is controlled by dissolution of form II in heptane, whereas the transformation in hexane and octane was firstly controlled by dissolution of solid-state form and then controlled by growth of form I. Copyright © 2018 American Pharmacists Association®. Published by Elsevier Inc. All rights reserved.

Parameter estimation in linear models of the human operator in a closed loop with application of deterministic test signals

NASA Technical Reports Server (NTRS)

Vanlunteren, A.; Stassen, H. G.

1973-01-01

Parameter estimation techniques are discussed with emphasis on unbiased estimates in the presence of noise. A distinction between open and closed loop systems is made. A method is given based on the application of external forcing functions consisting of a sun of sinusoids; this method is thus based on the estimation of Fourier coefficients and is applicable for models with poles and zeros in open and closed loop systems.

Design of a radio telescope surface segment actuator based on a form-closed eccentric cam

NASA Astrophysics Data System (ADS)

Smith, David R.

2014-07-01

As radio telescopes have reached larger diameters and higher frequencies, it is typically not possible to meet their surface accuracy specifications using passive homology-based designs. The most common solution to this problem in the current generation of large, high-frequency radio telescopes is to employ a system of linear actuators to correct the surface shape of the primary reflector. The exact specifications of active surface actuators vary with the telescope. However, they have many common features, some of which drive their design. In general, these actuators must provide precise and repeatable positioning under significant loads during operation and they must withstand even higher loads for survival conditions. For general safety, they typically must hold position in the event of a power failure and must incorporate position limits, whether electrical, mechanical, or both. Because the number of actuators is generally high for large active surfaces (hundreds or even thousands of actuators), they must also be reliable and of reasonable individual cost. Finally, for maximum flexibility in their installation, they must be compact. This paper presents a concept for an active surface actuator based on a form-closed eccentric cam (kinematically, a Scotch Yoke mechanism). Such a design is limited in stroke, but offers potential advantages in terms of manufacture, compactness, measurement, and survival loading. The paper demonstrates that some of the expected advantages cannot be practically realized, due to dimensions that are driven by survival loading conditions. As a result, this concept is likely to offer an advantage over conventional screw-type actuators only for cases where actuator runaway and stall are the driving considerations.

Modeling Multiple Human-Automation Distributed Systems using Network-form Games

NASA Technical Reports Server (NTRS)

Brat, Guillaume

2012-01-01

The paper describes at a high-level the network-form game framework (based on Bayes net and game theory), which can be used to model and analyze safety issues in large, distributed, mixed human-automation systems such as NextGen.

Hydrological Modeling of the Jezero Crater Outlet-Forming Flood

NASA Technical Reports Server (NTRS)

Fassett, C. I.; Goudge, T. A.

2017-01-01

Abundant evidence exists for lakes on Mars both from orbital observations [e.g., 1-3] and in situ exploration [e.g., 4-5]. These lakes can be divided into two classes: those that were hydrologically closed, so their source valley(s) terminated at the basin [3], and those that were hydrologically open, where there was sufficient flow from inlet valley(s) to cause the lake to breach and form an outlet valley [2]. It is easier to be confident from orbital data alone that a standing body of water must have existed in open basins, because there is no other way for their perched outlet valleys to form. The majority of basins fed by valley networks, rather than by isolated inlet valleys, are open [6], with some important exceptions (e.g., Gale Crater). Jezero crater (Fig. 1) is one of the most well-studied open basin paleolakes on Mars, with a breach that re-mains well above the lowest part of the crater floor, and two sedimentary fans at its northwestern margin that are likely deltaic in origin [7-9]. CRISM observations of these sediments indicate they host a variety of alteration minerals [9-11], including smectite and carbonate, and both the mineralogy of the sediments and their settings suggest they have a strong potential for preserving organic materials [10]. As a result, Jezero is a strong candidate landing site for the Mars 2020 rover. Approximate formative discharges have been estimated for its well-preserved western fan (Q approximately 500m3/s) [7], but to our knowledge, no estimates for the dis-charges associated with formation and incision of its outlet valley have been presented. Indeed, only a few studies [e.g., 12-14] have attempted to reconstruct the formation of outlet breaches broadly similar to Jezero anywhere on Mars, despite the apparent commonality of basins with large outlets [e.g., 2]. The outlet valley formed as a dam breach when the lake overflowed. In such an event, the growth and incision of the breach is directly coupled to flood discharge

Finding the Two-Way Street: Women from Mother-Present/Father-Absent Homes and Their Ability to Make Close Female Friendships

ERIC Educational Resources Information Center

Marote, Melissa A.

2011-01-01

This heuristic study involving seven coresearchers, which included the author, explores the experiences of women from mother-present/father-absent homes and their ability to form and maintain close female friendships. The heuristic research model was chosen to provide the opportunity to conduct research in a very personalized, collaborative way…

Model-Based, Closed-Loop Control of PZT Creep for Cavity Ring-Down Spectroscopy.

PubMed

McCartt, A D; Ognibene, T J; Bench, G; Turteltaub, K W

2014-09-01

Cavity ring-down spectrometers typically employ a PZT stack to modulate the cavity transmission spectrum. While PZTs ease instrument complexity and aid measurement sensitivity, PZT hysteresis hinders the implementation of cavity-length-stabilized, data-acquisition routines. Once the cavity length is stabilized, the cavity's free spectral range imparts extreme linearity and precision to the measured spectrum's wavelength axis. Methods such as frequency-stabilized cavity ring-down spectroscopy have successfully mitigated PZT hysteresis, but their complexity limits commercial applications. Described herein is a single-laser, model-based, closed-loop method for cavity length control.

Closed Small Cell Clouds

Atmospheric Science Data Center

2013-04-19

... (right)   The structure of tightly packed "closed cells" in a layer of marine stratocumulus over the southeastern Pacific Ocean ... they are bright and abundant, and reflect a large amount of solar energy toward space. They are difficult to represent in climate models ...

Fragmentation of urban forms and the environmental consequences: results from a high-spatial resolution model system

NASA Astrophysics Data System (ADS)

Tang, U. W.; Wang, Z. S.

2008-10-01

Each city has its unique urban form. The importance of urban form on sustainable development has been recognized in recent years. Traditionally, air quality modelling in a city is in a mesoscale with grid resolution of kilometers, regardless of its urban form. This paper introduces a GIS-based air quality and noise model system developed to study the built environment of highly compact urban forms. Compared with traditional mesoscale air quality model system, the present model system has a higher spatial resolution down to individual buildings along both sides of the street. Applying the developed model system in the Macao Peninsula with highly compact urban forms, the average spatial resolution of input and output data is as high as 174 receptor points per km2. Based on this input/output dataset with a high spatial resolution, this study shows that even the highly compact urban forms can be fragmented into a very small geographic scale of less than 3 km2. This is due to the significant temporal variation of urban development. The variation of urban form in each fragment in turn affects air dispersion, traffic condition, and thus air quality and noise in a measurable scale.

SOYCHMBR.I - A model designed for the study of plant growth in a closed chamber

NASA Technical Reports Server (NTRS)

Reinhold, C.

1982-01-01

The analytical model SOYCHMBER.I, an update and alteration of the SOYMOD/OARDC model, for describing the total processes experienced by a plant in a controlled mass environment is outlined. The model is intended for use with growth chambers for examining plant growth in a completely controlled environment, leading toward a data base for the design of spacecraft food supply systems. SOYCHMBER.I accounts for the assimilation, respiration, and partitioning of photosynthate and nitrogen compounds among leaves, stems, roots, and potentially, flowers of the soybean plant. The derivation of the governing equations is traced, and the results of the prediction of CO2 dynamics for a seven day experiment with rice in a closed chamber are reported, together with data from three model runs for soybean. It is concluded that the model needs expansion to account for factors such as relative humidity.

A mixed model for the relationship between climate and human cranial form.

PubMed

Katz, David C; Grote, Mark N; Weaver, Timothy D

2016-08-01

We expand upon a multivariate mixed model from quantitative genetics in order to estimate the magnitude of climate effects in a global sample of recent human crania. In humans, genetic distances are correlated with distances based on cranial form, suggesting that population structure influences both genetic and quantitative trait variation. Studies controlling for this structure have demonstrated significant underlying associations of cranial distances with ecological distances derived from climate variables. However, to assess the biological importance of an ecological predictor, estimates of effect size and uncertainty in the original units of measurement are clearly preferable to significance claims based on units of distance. Unfortunately, the magnitudes of ecological effects are difficult to obtain with distance-based methods, while models that produce estimates of effect size generally do not scale to high-dimensional data like cranial shape and form. Using recent innovations that extend quantitative genetics mixed models to highly multivariate observations, we estimate morphological effects associated with a climate predictor for a subset of the Howells craniometric dataset. Several measurements, particularly those associated with cranial vault breadth, show a substantial linear association with climate, and the multivariate model incorporating a climate predictor is preferred in model comparison. Previous studies demonstrated the existence of a relationship between climate and cranial form. The mixed model quantifies this relationship concretely. Evolutionary questions that require population structure and phylogeny to be disentangled from potential drivers of selection may be particularly well addressed by mixed models. Am J Phys Anthropol 160:593-603, 2016. © 2015 Wiley Periodicals, Inc. © 2015 Wiley Periodicals, Inc.

The closing behavior of mechanical aortic heart valve prostheses.

PubMed

Lu, Po-Chien; Liu, Jia-Shing; Huang, Ren-Hong; Lo, Chi-Wen; Lai, Ho-Cheng; Hwang, Ned H C

2004-01-01

Mechanical artificial heart valves rely on reverse flow to close their leaflets. This mechanism creates regurgitation and water hammer effects that may form cavitations, damage blood cells, and cause thromboembolism. This study analyzes closing mechanisms of monoleaflet (Medtronic Hall 27), bileaflet (Carbo-Medics 27; St. Jude Medical 27; Duromedics 29), and trileaflet valves in a circulatory mock loop, including an aortic root with three sinuses. Downstream flow field velocity was measured via digital particle image velocimetry (DPIV). A high speed camera (PIVCAM 10-30 CCD video camera) tracked leaflet movement at 1000 frames/s. All valves open in 40-50 msec, but monoleaflet and bileaflet valves close in much less time (< 35 msec) than the trileaflet valve (>75 msec). During acceleration phase of systole, the monoleaflet forms a major and minor flow, the bileaflet has three jet flows, and the trileaflet produces a single central flow like physiologic valves. In deceleration phase, the aortic sinus vortices hinder monoleaflet and bileaflet valve closure until reverse flows and high negative transvalvular pressure push the leaflets rapidly for a hard closure. Conversely, the vortices help close the trileaflet valve more softly, probably causing less damage, lessening back flow, and providing a washing effect that may prevent thrombosis formation.

Stress distribution in the temporo-mandibular joint discs during jaw closing: a high-resolution three-dimensional finite-element model analysis.

PubMed

Savoldelli, Charles; Bouchard, Pierre-Olivier; Loudad, Raounak; Baque, Patrick; Tillier, Yannick

2012-07-01

This study aims at analysing the stresses distribution in the temporomandibular joint (TMJ) using a complete high-resolution finite element model (FE Model). This model is used here to analyse the stresses distribution in the discs during a closing jaw cycle. In the end, this model enables the prediction of the stress evolution in the TMJ disc submitted to various loadings induced by mandibular trauma, surgery or parafunction. The geometric data for the model were obtained from MRI and CT scans images of a healthy male patient. Surface and volume meshes were successively obtained using a 3D image segmentation software (AMIRA(®)). Bone components of skull and mandible, both of joint discs, temporomandibular capsules and ligaments and dental arches were meshed as separate bodies. The volume meshes were transferred to the FE analysis software (FORGE(®)). Material properties were assigned for each region. Boundary conditions for closing jaw simulations were represented by different load directions of jaws muscles. The von Mises stresses distribution in both joint discs during closing conditions was analyzed. The pattern of von Mises stresses in the TMJ discs is non-symmetric and changed continuously during jaw movement. Maximal stress is reached on the surface disc in areas in contact with others bodies. The three-dimension finite element model of masticatory system will make it possible to simulate different conditions that appear to be important in the cascade of events leading to joint damage.

Additive Manufacturing Modeling and Simulation A Literature Review for Electron Beam Free Form Fabrication

NASA Technical Reports Server (NTRS)

Seufzer, William J.

2014-01-01

Additive manufacturing is coming into industrial use and has several desirable attributes. Control of the deposition remains a complex challenge, and so this literature review was initiated to capture current modeling efforts in the field of additive manufacturing. This paper summarizes about 10 years of modeling and simulation related to both welding and additive manufacturing. The goals were to learn who is doing what in modeling and simulation, to summarize various approaches taken to create models, and to identify research gaps. Later sections in the report summarize implications for closed-loop-control of the process, implications for local research efforts, and implications for local modeling efforts.

Bidisperse silica nanoparticles close-packed monolayer on silicon substrate by three step spin method

NASA Astrophysics Data System (ADS)

Khanna, Sakshum; Marathey, Priyanka; Utsav, Chaliawala, Harsh; Mukhopadhyay, Indrajit

2018-05-01

We present the studies on the structural properties of monolayer Bidisperse silica (SiO2) nanoparticles (BDS) on Silicon (Si-100) substrate using spin coating technique. The Bidisperse silica nanoparticle was synthesised by the modified sol-gel process. Nanoparticles on the substrate are generally assembled in non-close/close-packed monolayer (CPM) form. The CPM form is obtained by depositing the colloidal suspension onto the silicon substrate using complex techniques. Here we report an effective method for forming a monolayer of bidisperse silica nanoparticle by three step spin coating technique. The samples were prepared by mixing the monodisperse solutions of different particles size 40 and 100 nm diameters. The bidisperse silica nanoparticles were self-assembled on the silicon substrate forming a close-packed monolayer film. The scanning electron microscope images of bidisperse films provided in-depth film structure of the film. The maximum surface coverage obtained was around 70-80%.

Regression models of monthly water-level change in and near the Closed Basin Division of the San Luis Valley, south-central Colorado

USGS Publications Warehouse

Watts, Kenneth R.

1995-01-01

The Bureau of Reclamation is developing a water-resource project, the Closed Basin Division, in the San Luis Valley of south-central Colorado that is designed to salvage unconfined ground water that currently is discharged as evapotranspiration. The water table in and near the 130,000-acre Closed Basin Division area will be lowered by an annual withdrawal of as much as 100,000 acre-feet of ground water from the unconfined aquifer. The legislation authorizing the project limits resulting drawdown of the water table in preexisting irrigation and domestic wells outside the Closed Basin Division to a maximum of 2 feet. Water levels in the closed basin in the northern part of the San Luis Valley historically have fluctuated more than 2 feet in response to water-use practices and variation of climatically controlled recharge and discharge. Declines of water levels in nearby wells that are caused by withdrawals in the Closed Basin Division can be quantified if water-level fluctuations that result from other water-use practices and climatic variations can be estimated. This study was done to evaluate water-level change at selected observation wells in and near the Closed Basin Division. Regression models of monthly water-level change were developed to predict monthly water-level change in 46 selected observation wells. Predictions of monthly water-level change are based on one or more of the following: elapsed time, cosine and sine functions with an annual period, streamflow depletion of the Rio Grande, electrical use for agricultural purposes, runoff into the closed basin, precipitation, and mean air temperature. Regression models for five of the wells include only an intercept term and either an elapsed-time term or terms determined by the cosine and sine functions. Regression models for the other 41 wells include 1 to 4 of the 5 other variables, which can vary from month to month and from year to year. Serial correlation of the residuals was detected in 24 of the

Closed Loop Control of Oxygen Delivery and Oxygen Generation

DTIC Science & Technology

2017-08-01

AFRL-SA-WP-SR-2017-0024 Closed Loop Control of Oxygen Delivery and Oxygen Generation Dr. Jay Johannigman1, Richard Branson1...for failing to comply with a collection of information if it does not display a currently valid OMB control number. PLEASE DO NOT RETURN YOUR FORM TO...TITLE AND SUBTITLE Closed Loop Control of Oxygen Delivery and Oxygen Generation 5a. CONTRACT NUMBER FA8650-10-2-6140 5b. GRANT NUMBER

Crenactin from Pyrobaculum calidifontis is closely related to actin in structure and forms steep helical filaments

PubMed Central

Izoré, Thierry; Duman, Ramona; Kureisaite-Ciziene, Danguole; Löwe, Jan

2014-01-01

Polymerising proteins of the actin family are nearly ubiquitous. Crenactins, restricted to Crenarchaea, are more closely related to actin than bacterial MreB. Crenactins occur in gene clusters hinting at an unknown, but conserved function. We solved the crystal structure of crenactin at 3.2 Å resolution. The protein crystallises as a continuous right-handed helix with 8 subunits per complete turn, spanning 419 Å. The structure of crenactin shows several loops that are longer than in actin, but overall, crenactin is closely related to eukaryotic actin, with an RMSD of 1.6 Å. Crenactin filaments imaged by electron microscopy showed polymers with very similar helical parameters. PMID:24486010

Evaluating Nextgen Closely Spaced Parallel Operations Concepts with Validated Human Performance Models: Flight Deck Guidelines

NASA Technical Reports Server (NTRS)

Hooey, Becky Lee; Gore, Brian Francis; Mahlstedt, Eric; Foyle, David C.

2013-01-01

The objectives of the current research were to develop valid human performance models (HPMs) of approach and land operations; use these models to evaluate the impact of NextGen Closely Spaced Parallel Operations (CSPO) on pilot performance; and draw conclusions regarding flight deck display design and pilot-ATC roles and responsibilities for NextGen CSPO concepts. This document presents guidelines and implications for flight deck display designs and candidate roles and responsibilities. A companion document (Gore, Hooey, Mahlstedt, & Foyle, 2013) provides complete scenario descriptions and results including predictions of pilot workload, visual attention and time to detect off-nominal events.

24 CFR 3285.803 - Interior close-up.

Code of Federal Regulations, 2010 CFR

2010-04-01

...: Specific designs must be approved by a DAPIA and included in the home manufacturer installation... DEVELOPMENT MODEL MANUFACTURED HOME INSTALLATION STANDARDS Exterior and Interior Close-Up § 3285.803 Interior... doors. (b) Interior close up items necessary to join all sections of the home or items subject to...

24 CFR 3285.801 - Exterior close-up.

Code of Federal Regulations, 2010 CFR

2010-04-01

... home manufacturer must provide materials and designs for mate-line gaskets or other methods designed to... DEVELOPMENT MODEL MANUFACTURED HOME INSTALLATION STANDARDS Exterior and Interior Close-Up § 3285.801 Exterior close-up. (a) Exterior siding and roofing necessary to join all sections of the home must be installed...

Closing the Loop for Memory Prostheses: Detecting the Role of Hippocampal Neural Ensembles Using Nonlinear Models

PubMed Central

Hampson, Robert E.; Song, Dong; Chan, Rosa H.M.; Sweatt, Andrew J.; Riley, Mitchell R.; Goonawardena, Anushka V.; Marmarelis, Vasilis Z.; Gerhardt, Greg A.; Berger, Theodore W.; Deadwyler, Sam A.

2012-01-01

A major factor involved in providing closed loop feedback for control of neural function is to understand how neural ensembles encode online information critical to the final behavioral endpoint. This issue was directly assessed in rats performing a short-term delay memory task in which successful encoding of task information is dependent upon specific spatiotemporal firing patterns recorded from ensembles of CA3 and CA1 hippocampal neurons. Such patterns, extracted by a specially designed nonlinear multi-input multi-output (MIMO) nonlinear mathematical model, were used to predict successful performance online via a closed loop paradigm which regulated trial difficulty (time of retention) as a function of the “strength” of stimulus encoding. The significance of the MIMO model as a neural prosthesis has been demonstrated by substituting trains of electrical stimulation pulses to mimic these same ensemble firing patterns. This feature was used repeatedly to vary “normal” encoding as a means of understanding how neural ensembles can be “tuned” to mimic the inherent process of selecting codes of different strength and functional specificity. The capacity to enhance and tune hippocampal encoding via MIMO model detection and insertion of critical ensemble firing patterns shown here provides the basis for possible extension to other disrupted brain circuitry. PMID:22498704

Agreement in the determination of preformed wire shape templates on plaster models and customized digital arch form diagrams on digital models.

PubMed

Camardella, Leonardo Tavares; Sá, Maiara da Silva Bezerra; Guimarães, Luciana Campos; Vilella, Beatriz de Souza; Vilella, Oswaldo de Vasconcellos

2018-03-01

The aim of this study was to verify the accuracy of preformed wire shape templates on plaster models and those of customized digital arch form diagrams on digital models. Twenty pairs of dental plaster models were randomly selected from the archives of the Department of Orthodontics of Federal Fluminense University, Niterói, Rio de Janeiro, Brazil. All plaster model samples were scanned in a plaster model scanner to create the respective digital models. Three examiners defined the arch form on the mandibular arch of these models by selecting the ideal preformed wire shape template on each plaster model or by making a customized digital arch form on the digital models using a digital arch form customization tool. These 2 arch forms were superimposed by the best-fit method. The greatest differences in the 6 regions on the superimposed arches were evaluated. Each examiner presented a descriptive analysis with the means, standard deviation, and minimum and maximum intervals of the differences on the superimpositions. Intraclass correlation coefficient and paired t tests were used to evaluate the accuracy of the superimpositions. Among the 6 regions analyzed in the superimpositions, the largest differences in the anterior and premolar regions were considered clinically insignificant, whereas the largest differences in the right molar region, especially the second molar area, were considered clinically significant by all 3 examiners. The intraclass correlation coefficients showed a weak correlation in the premolar region and moderate correlations in the anterior and molar regions. The paired t test showed statistically significant differences in the left anterior and premolar regions. The superimpositions between the arch forms on plaster and digital models were considered accurate, and the differences were not clinically significant, with the exception of the second molar area. Despite the favorable results, the requirement of correcting some software problems may

A simple model for indentation creep

NASA Astrophysics Data System (ADS)

Ginder, Ryan S.; Nix, William D.; Pharr, George M.

2018-03-01

A simple model for indentation creep is developed that allows one to directly convert creep parameters measured in indentation tests to those observed in uniaxial tests through simple closed-form relationships. The model is based on the expansion of a spherical cavity in a power law creeping material modified to account for indentation loading in a manner similar to that developed by Johnson for elastic-plastic indentation (Johnson, 1970). Although only approximate in nature, the simple mathematical form of the new model makes it useful for general estimation purposes or in the development of other deformation models in which a simple closed-form expression for the indentation creep rate is desirable. Comparison to a more rigorous analysis which uses finite element simulation for numerical evaluation shows that the new model predicts uniaxial creep rates within a factor of 2.5, and usually much better than this, for materials creeping with stress exponents in the range 1 ≤ n ≤ 7. The predictive capabilities of the model are evaluated by comparing it to the more rigorous analysis and several sets of experimental data in which both the indentation and uniaxial creep behavior have been measured independently.

Using artificial neural networks to model aluminium based sheet forming processes and tools details

NASA Astrophysics Data System (ADS)

Mekras, N.

2017-09-01

In this paper, a methodology and a software system will be presented concerning the use of Artificial Neural Networks (ANNs) for modeling aluminium based sheet forming processes. ANNs models’ creation is based on the training of the ANNs using experimental, trial and historical data records of processes’ inputs and outputs. ANNs models are useful in cases that processes’ mathematical models are not accurate enough, are not well defined or are missing e.g. in cases of complex product shapes, new material alloys, new process requirements, micro-scale products, etc. Usually, after the design and modeling of the forming tools (die, punch, etc.) and before mass production, a set of trials takes place at the shop floor for finalizing processes and tools details concerning e.g. tools’ minimum radii, die/punch clearance, press speed, process temperature, etc. and in relation with the material type, the sheet thickness and the quality achieved from the trials. Using data from the shop floor trials and forming theory data, ANNs models can be trained and created, and can be used to estimate processes and tools final details, hence supporting efficient set-up of processes and tools before mass production starts. The proposed ANNs methodology and the respective software system are implemented within the EU H2020 project LoCoMaTech for the aluminium-based sheet forming process HFQ (solution Heat treatment, cold die Forming and Quenching).

On open and closed field line regions in Tsyganenko's field model and their possible associations with horse collar auroras

NASA Technical Reports Server (NTRS)

Birn, J.; Hones, E. W., Jr.; Craven, J. D.; Frank, L. A.; Elphinstone, R. D.; Stern, D. P.

1991-01-01

The boundary between open and closed field lines is investigated in the empirical Tsyganenko (1987) magnetic field model. All field lines extending to distances beyond -70 R(E), the tailward velocity limit of the Tsyganenko model are defined as open, while all other field lines, which cross the equatorial plane earthward of -70 R(E) and are connected with the earth at both ends, are assumed closed. It is found that this boundary at the surface of the earth, identified as the polar cap boundary, can exhibit the arrowhead shape, pointed toward the sun, which is found in horse collar auroras. For increasing activity levels, the polar cap increases in area and becomes rounder, so that the arrowhead shape is less pronounced. The presence of a net B(y) component can also lead to considerable rounding of the open flux region. The arrowhead shape is found to be closely associated with the increase of B(z) from the midnight region to the flanks of the tail, consistent with a similar increase of the plasma sheet thickness.

CLOSED-FIELD CORONAL HEATING DRIVEN BY WAVE TURBULENCE

DOE Office of Scientific and Technical Information (OSTI.GOV)

Downs, Cooper; Lionello, Roberto; Mikić, Zoran

To simulate the energy balance of coronal plasmas on macroscopic scales, we often require the specification of the coronal heating mechanism in some functional form. To go beyond empirical formulations and to build a more physically motivated heating function, we investigate the wave-turbulence-driven (WTD) phenomenology for the heating of closed coronal loops. Our implementation is designed to capture the large-scale propagation, reflection, and dissipation of wave turbulence along a loop. The parameter space of this model is explored by solving the coupled WTD and hydrodynamic evolution in 1D for an idealized loop. The relevance to a range of solar conditionsmore » is also established by computing solutions for over one hundred loops extracted from a realistic 3D coronal field. Due to the implicit dependence of the WTD heating model on loop geometry and plasma properties along the loop and at the footpoints, we find that this model can significantly reduce the number of free parameters when compared to traditional empirical heating models, and still robustly describe a broad range of quiet-Sun and active region conditions. The importance of the self-reflection term in producing relatively short heating scale heights and thermal nonequilibrium cycles is also discussed.« less

Closed-field Coronal Heating Driven by Wave Turbulence

NASA Astrophysics Data System (ADS)

Downs, Cooper; Lionello, Roberto; Mikić, Zoran; Linker, Jon A.; Velli, Marco

2016-12-01

To simulate the energy balance of coronal plasmas on macroscopic scales, we often require the specification of the coronal heating mechanism in some functional form. To go beyond empirical formulations and to build a more physically motivated heating function, we investigate the wave-turbulence-driven (WTD) phenomenology for the heating of closed coronal loops. Our implementation is designed to capture the large-scale propagation, reflection, and dissipation of wave turbulence along a loop. The parameter space of this model is explored by solving the coupled WTD and hydrodynamic evolution in 1D for an idealized loop. The relevance to a range of solar conditions is also established by computing solutions for over one hundred loops extracted from a realistic 3D coronal field. Due to the implicit dependence of the WTD heating model on loop geometry and plasma properties along the loop and at the footpoints, we find that this model can significantly reduce the number of free parameters when compared to traditional empirical heating models, and still robustly describe a broad range of quiet-Sun and active region conditions. The importance of the self-reflection term in producing relatively short heating scale heights and thermal nonequilibrium cycles is also discussed.

Using Shock Waves to Improve the Acoustic Properties of Closed-Cell Foams

NASA Astrophysics Data System (ADS)

Brouillette, M.; Hébert, C.; Atalla, N.; Doutres, O.

Foam microstructure can be seen as a collection of interlinked struts forming a packing of cells interconnected to others through pores. Materials with a totality of pores closed by thin membranes are called closed-cell foams. The filtration and acoustic efficiency of closed-cell foams is poor compared to open-cell foams since it is very difficult for the fluid or the acoustic waves to penetrate inside the material.

Coupling sensing to crop models for closed-loop plant production in advanced life support systems

NASA Astrophysics Data System (ADS)

Cavazzoni, James; Ling, Peter P.

1999-01-01

We present a conceptual framework for coupling sensing to crop models for closed-loop analysis of plant production for NASA's program in advanced life support. Crop status may be monitored through non-destructive observations, while models may be independently applied to crop production planning and decision support. To achieve coupling, environmental variables and observations are linked to mode inputs and outputs, and monitoring results compared with model predictions of plant growth and development. The information thus provided may be useful in diagnosing problems with the plant growth system, or as a feedback to the model for evaluation of plant scheduling and potential yield. In this paper, we demonstrate this coupling using machine vision sensing of canopy height and top projected canopy area, and the CROPGRO crop growth model. Model simulations and scenarios are used for illustration. We also compare model predictions of the machine vision variables with data from soybean experiments conducted at New Jersey Agriculture Experiment Station Horticulture Greenhouse Facility, Rutgers University. Model simulations produce reasonable agreement with the available data, supporting our illustration.

Model-Based, Closed-Loop Control of PZT Creep for Cavity Ring-Down Spectroscopy

PubMed Central

McCartt, A D; Ognibene, T J; Bench, G; Turteltaub, K W

2014-01-01

Cavity ring-down spectrometers typically employ a PZT stack to modulate the cavity transmission spectrum. While PZTs ease instrument complexity and aid measurement sensitivity, PZT hysteresis hinders the implementation of cavity-length-stabilized, data-acquisition routines. Once the cavity length is stabilized, the cavity’s free spectral range imparts extreme linearity and precision to the measured spectrum’s wavelength axis. Methods such as frequency-stabilized cavity ring-down spectroscopy have successfully mitigated PZT hysteresis, but their complexity limits commercial applications. Described herein is a single-laser, model-based, closed-loop method for cavity length control. PMID:25395738

Algorithms for a Closed-Loop Artificial Pancreas: The Case for Model Predictive Control

PubMed Central

Bequette, B. Wayne

2013-01-01

The relative merits of model predictive control (MPC) and proportional-integral-derivative (PID) control are discussed, with the end goal of a closed-loop artificial pancreas (AP). It is stressed that neither MPC nor PID are single algorithms, but rather are approaches or strategies that may be implemented very differently by different engineers. The primary advantages to MPC are that (i) constraints on the insulin delivery rate (and/or insulin on board) can be explicitly included in the control calculation; (ii) it is a general framework that makes it relatively easy to include the effect of meals, exercise, and other events that are a function of the time of day; and (iii) it is flexible enough to include many different objectives, from set-point tracking (target) to zone (control to range). In the end, however, it is recognized that the control algorithm, while important, represents only a portion of the effort required to develop a closed-loop AP. Thus, any number of algorithms/approaches can be successful—the engineers involved in the design must have experience with the particular technique, including the important experience of implementing the algorithm in human studies and not simply through simulation studies. PMID:24351190

CFD investigation of pentamaran ship model with chine hull form on the resistance characteristics

NASA Astrophysics Data System (ADS)

Yanuar; Sulistyawati, W.

2018-03-01

This paper presents an investigation of pentamaran hull form with chine hull form to the effects of outriggers position, asymmetry, and deadrise angles on the resistance characteristics. The investigation to the resistance characteristics by modelling pentamaran hull form using chine with symmetrical main hull and asymmetric outboard on the variation deadrise angles: 25°, 30°, 35° and Froude number 0,1 to 0,7. On calm water resistance characteristics of six pentamaran models with chine-hull form examined by variation of deadrise angles by using CFD. Comparation with Wigley hull form, the maximum resistance drag reduction of the chine hull form was reduced by 15.81% on deadrise 25°, 13.8% on deadrise 30°, and 20.38% on deadrise 35°. While the smallest value of total resistance coefficient was generated from chine 35° at R/L:1/14 and R/L:1/7. Optimum hull form for minimum resistance has been obtained, so it is interesting to continue with angle of entrance and stem angle of hull for further research.

77 FR 46632 - Closed Captioning of Internet Protocol-Delivered Video Programming: Implementation of the Twenty...

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