Space Suit Environment Testing of the Orion Atmosphere Revitalization Technology

NASA Technical Reports Server (NTRS)

Button, Amy B.; Sweterlitsch, Jeffrey J.; Cox, Marlon R.

2010-01-01

An amine-based carbon dioxide (CO2) and water vapor sorbent in pressure-swing regenerable beds has been developed by Hamilton Sundstrand and baselined for the Orion Atmosphere Revitalization System (ARS). In three previous years at this conference, reports were presented on extensive Johnson Space Center (JSC) testing of this technology. That testing was performed in a sea-level pressure environment with both simulated and real human metabolic loads, and in both open and closed-loop configurations. The Orion ARS is designed to also support space-suited operations in a depressurized cabin, so the next step in developmental testing at JSC was to test the ARS technology in a typical closed space suit-loop environment with low-pressure oxygen inside the process loop and vacuum outside the loop. This was the first instance of low-pressure, high-oxygen, closed-loop testing of the Orion ARS technology, and it was conducted with simulated human metabolic loads in March 2009. The test investigated pressure drops and flow balancing through two different styles of prototype suit umbilical connectors. General swing-bed performance was tested with both umbilical configurations, as well as with a short jumper line installed in place of the umbilicals. Other interesting results include observations on the thermal effects of swing-bed operation in a vacuum environment and a recommendation of cycle time to maintain acceptable suit atmospheric CO2 and moisture levels.

Singlet oxygen generator for a supersonic chemical oxygen iodine laser: parametric study and recovery of chemicals

NASA Astrophysics Data System (ADS)

Spalek, Otomar; Kodymova, Jarmila

1997-04-01

A jet singlet oxygen generator for a supersonic chemical oxygen-iodine laser was studied including singlet delta oxygen, O2(1(Delta) g), and residual chlorine concentration measurements. The investigation was intended mainly for a water vapor measurement in gas effluent of generator in dependence on properties of liquid jets: a chemical composition and temperature of the input liquid (alkaline solution of hydrogen peroxide), a liquid jets diameter and their geometrical arrangement. Effects of these parameters on output power of a small-scale supersonic laser were studied as well. Possible approaches to a chemical fuels management in a chemical oxygen-iodine laser for industrial applications are considered. An 'open loop' cycle with a possible use of sodium hydroxide, and a 'closed loop' cycle with a regeneration of both potassium hydroxide and hydrogen peroxide are discussed.

A low power flash-FPGA based brain implant micro-system of PID control.

PubMed

Lijuan Xia; Fattah, Nabeel; Soltan, Ahmed; Jackson, Andrew; Chester, Graeme; Degenaar, Patrick

2017-07-01

In this paper, we demonstrate that a low power flash FPGA based micro-system can provide a low power programmable interface for closed-loop brain implant inter- faces. The proposed micro-system receives recording local field potential (LFP) signals from an implanted probe, performs closed-loop control using a first order control system, then converts the signal into an optogenetic control stimulus pattern. Stimulus can be implemented through optoelectronic probes. The long term target is for both fundamental neuroscience applications and for clinical use in treating epilepsy. Utilizing our device, closed-loop processing consumes only 14nJ of power per PID cycle compared to 1.52μJ per cycle for a micro-controller implementation. Compared to an application specific digital integrated circuit, flash FPGA's are inherently programmable.

Full-Authority Fault-Tolerant Electronic Engine Control Systems for Variable Cycle Engines.

DTIC Science & Technology

1981-12-01

Geometry or Fuel Flow Scheduled as a Function of Engine State, i.e. FIGV = f( N1 C2 ) Closed Loop - Geometry or Fuel Flow Modulated To Maintain an Engine...Low Pressure Turbine Inlet Area (A41) Closed Loop (Integral) N2, T22 Core Stream Exhaust Nozzle Area (AJE) Closed Loop (Integral) N1 , T2 Duct Stream...to remain at the breakpoint value while low rotor speed reference ( N1 reference) is scheduled to decrease as a function of power lever angle (PLA), to

Gas Foil Bearing Technology Advancements for Closed Brayton Cycle Turbines

NASA Technical Reports Server (NTRS)

Howard, Samuel A.; Bruckner, Robert J.; DellaCorte, Christopher; Radil, Kevin C.

2007-01-01

Closed Brayton Cycle (CBC) turbine systems are under consideration for future space electric power generation. CBC turbines convert thermal energy from a nuclear reactor, or other heat source, to electrical power using a closed-loop cycle. The operating fluid in the closed-loop is commonly a high pressure inert gas mixture that cannot tolerate contamination. One source of potential contamination in a system such as this is the lubricant used in the turbomachine bearings. Gas Foil Bearings (GFB) represent a bearing technology that eliminates the possibility of contamination by using the working fluid as the lubricant. Thus, foil bearings are well suited to application in space power CBC turbine systems. NASA Glenn Research Center is actively researching GFB technology for use in these CBC power turbines. A power loss model has been developed, and the effects of a very high ambient pressure, start-up torque, and misalignment, have been observed and are reported here.

Non-Nuclear Validation Test Results of a Closed Brayton Cycle Test-Loop

NASA Astrophysics Data System (ADS)

Wright, Steven A.

2007-01-01

Both NASA and DOE have programs that are investigating advanced power conversion cycles for planetary surface power on the moon or Mars, or for next generation nuclear power plants on earth. Although open Brayton cycles are in use for many applications (combined cycle power plants, aircraft engines), only a few closed Brayton cycles have been tested. Experience with closed Brayton cycles coupled to nuclear reactors is even more limited and current projections of Brayton cycle performance are based on analytic models. This report describes and compares experimental results with model predictions from a series of non-nuclear tests using a small scale closed loop Brayton cycle available at Sandia National Laboratories. A substantial amount of testing has been performed, and the information is being used to help validate models. In this report we summarize the results from three kinds of tests. These tests include: 1) test results that are useful for validating the characteristic flow curves of the turbomachinery for various gases ranging from ideal gases (Ar or Ar/He) to non-ideal gases such as CO2, 2) test results that represent shut down transients and decay heat removal capability of Brayton loops after reactor shut down, and 3) tests that map a range of operating power versus shaft speed curve and turbine inlet temperature that are useful for predicting stable operating conditions during both normal and off-normal operating behavior. These tests reveal significant interactions between the reactor and balance of plant. Specifically these results predict limited speed up behavior of the turbomachinery caused by loss of load, the conditions for stable operation, and for direct cooled reactors, the tests reveal that the coast down behavior during loss of power events can extend for hours provided the ultimate heat sink remains available.

Closed cycle electric discharge laser design investigation

NASA Technical Reports Server (NTRS)

Baily, P. K.; Smith, R. C.

1978-01-01

Closed cycle CO2 and CO electric discharge lasers were studied. An analytical investigation assessed scale-up parameters and design features for CO2, closed cycle, continuous wave, unstable resonator, electric discharge lasing systems operating in space and airborne environments. A space based CO system was also examined. The program objectives were the conceptual designs of six CO2 systems and one CO system. Three airborne CO2 designs, with one, five, and ten megawatt outputs, were produced. These designs were based upon five minute run times. Three space based CO2 designs, with the same output levels, were also produced, but based upon one year run times. In addition, a conceptual design for a one megawatt space based CO laser system was also produced. These designs include the flow loop, compressor, and heat exchanger, as well as the laser cavity itself. The designs resulted in a laser loop weight for the space based five megawatt system that is within the space shuttle capacity. For the one megawatt systems, the estimated weight of the entire system including laser loop, solar power generator, and heat radiator is less than the shuttle capacity.

Preliminary design of a supercritical CO2 wind tunnel

NASA Astrophysics Data System (ADS)

Re, B.; Rurale, A.; Spinelli, A.; Guardone, A.

2017-03-01

The preliminary design of a test-rig for non-ideal compressible-fluid flows of carbon dioxide is presented. The test-rig is conceived to investigate supersonic flows that are relevant to the study of non-ideal compressible-fluid flows in the close proximity of the critical point and of the liquid-vapor saturation curve, to the investigation of drop nucleation in compressors operating with supercritical carbon dioxide and and to the study of flow conditions similar to those encountered in turbines for Organic Rankine Cycle applications. Three different configurations are presented and examined: a batch-operating test-rig, a closed-loop Brayton cycle and a closed-loop Rankine cycle. The latter is preferred for its versatility and for economic reasons. A preliminary design of the main components is reported, including the heat exchangers, the chiller, the pumps and the test section.

Relative stability of the open and closed conformations of the active site loop of streptavidin

NASA Astrophysics Data System (ADS)

Ignacio J., General; Meirovitch, Hagai

2011-01-01

The eight-residue surface loop, 45-52 (Ser, Ala, Val, Gly, Asn, Ala, Glu, Ser), of the homotetrameric protein streptavidin has a "closed" conformation in the streptavidin-biotin complex, where the corresponding binding affinity is one of the strongest found in nature (ΔG ˜ -18 kcal/mol). However, in most of the crystal structures of apo (unbound) streptavidin, the loop conformation is "open" and typically exhibits partial disorder and high B-factors. Thus, it is plausible to assume that the loop structure is changed from open to closed upon binding of biotin, and the corresponding difference in free energy, ΔF = Fopen - Fclosed in the unbound protein, should therefore be considered in the total absolute free energy of binding. ΔF (which has generally been neglected) is calculated here using our "hypothetical scanning molecular-dynamics" (HSMD) method. We use a protein model in which only the atoms closest to the loop are considered (the "template") and they are fixed in the x-ray coordinates of the free protein; the x-ray conformation of the closed loop is attached to the same (unbound) template and both systems are capped with the same sphere of TIP3P water. Using the force field of the assisted model building with energy refinement (AMBER), we carry out two separate MD simulations (at temperature T = 300 K), starting from the open and closed conformations, where only the atoms of the loop and water are allowed to move (the template-water and template-loop interactions are considered). The absolute Fopen and Fclosed (of loop + water) are calculated from these trajectories, where the loop and water contributions are obtained by HSMD and a thermodynamic integration (TI) process, respectively. The combined HSMD-TI procedure leads to total (loop + water) ΔF = -27.1 ± 2.0 kcal/mol, where the entropy TΔS constitutes 34% of ΔF, meaning that the effect of S is significant and should not be ignored. Also, ΔS is positive, in accord with the high flexibility of the open loop observed in crystal structures, while the energy ΔE is unexpectedly negative, thus also adding to the stability of the open loop. The loop and the 250 capped water molecules are the largest system studied thus far, which constitutes a test for the efficiency of HSMD-TI; this efficiency and technical issues related to the implementation of the method are also discussed. Finally, the result for ΔF is a prediction that will be considered in the calculation of the absolute free energy of binding of biotin to streptavidin, which constitutes our next project.

Close-up view of sugar crystals in a water bubble within a metal loop on Expedition Six

NASA Image and Video Library

2003-03-15

ISS006-E-39299 (15 March 2003) --- A close up view of sugar crystals in a water bubble within a 50-millimeter (mm) metal loop was photographed by an Expedition Six crewmember. The experiment took place in the Destiny laboratory on the International Space Station (ISS).

Phase III integrated water recovery testing at MSFC - Partially closed hygiene loop and open potable loop results and lessons learned

NASA Technical Reports Server (NTRS)

Bagdigian, R. M.; Traweek, M. S.; Griffith, G. K.; Griffin, M. R.

1991-01-01

A series of tests has been conducted at the NASA Marshall Space Flight Center (MSFC) to evaluate the performance of a predevelopment water recovery system. Potable, hygiene, and urine reclamation subsystems were integrated with end-use equipment items and successfully operated in open and partially closed-loop modes, with man-in-the-loop, for a total of 28 days. Several significant subsystem physical anomalies were encountered during testing. Reclaimed potable and hygiene water generally met the current Space Station Freedom (SSF) water quality specifications for inorganic and microbiological constituents, but exceeded the maximum allowable concentrations for Total Organic Carbon (TOC). This paper summarizes the test objectives, system design, test activities/protocols, significant results/anomalies, and major lessons learned.

Space Suit Environment Testing of the Orion Atmosphere Revitalization Technology

NASA Technical Reports Server (NTRS)

Lin, Amy; Sweterlitsch, Jeffrey; Cox, Marlon

2009-01-01

An amine-based carbon dioxide (CO2) and water vapor sorbent in pressure-swing regenerable beds has been developed by Hamilton Sundstrand and baselined for the Orion Atmosphere Revitalization System (ARS). In two previous years at this conference, reports were presented on extensive Johnson Space Center (JSC) testing of this technology in a sea-level pressure environment with simulated human metabolic loads. Another paper at this year s conference discusses similar testing with real human metabolic loads, including some closed-loop testing with emergency breathing masks. The Orion ARS is designed to also support extravehicular activity operations from a depressurized cabin. The next step in developmental testing at JSC was, therefore, to test this ARS technology in a typical closed space suit loop environment with low-pressure pure oxygen inside the process loop and vacuum outside the loop. This was the first instance of low-pressure oxygen loop testing of a new Orion ARS technology, and was conducted with simulated human metabolic loads in December 2008. The test investigated pressure drops through two different styles of prototype suit umbilical connectors and general swing-bed performance with both umbilical configurations as well as with a short jumper line installed in place of the umbilicals. Other interesting results include observations on the thermal effects of swing-bed operation in a vacuum environment and a recommendation of cycle time to maintain acceptable atmospheric CO2 and moisture levels.

On the feasibility of closed-loop control of intra-aortic balloon pumping

NASA Technical Reports Server (NTRS)

Clark, J. W., Jr.; Bourland, H. M.; Kane, G. R.

1973-01-01

A closed-loop control scheme for the control of intra-aortic balloon pumping has been developed and tested in dog experiments. A performance index reflecting the general objectives of balloon-assist pumping is developed and a modified steepest ascent control algorithm is utilized for the selection of a proper operating point for the balloon during its pumping cycle. This paper attempts to indicate the feasibility of closed-loop control of balloon pumping, and particularly its flexibility in achieving both diastolic augmentation of mean aortic pressure and control of the level of end-diastolic pressure (EDP) an important factor in reducing heart work.

Closed-cycle gas dynamic laser design investigation

NASA Technical Reports Server (NTRS)

Ketch, G. W.; Young, W. E.

1977-01-01

A conceptual design study was made of a closed cycle gas-dynamic laser to provide definition of the major components in the laser loop. The system potential application is for long range power transmission by way of high power laser beams to provide satellite propulsion energy for orbit changing or station keeping. A parametric cycle optimization was conducted to establish the thermodynamic requirements for the system components. A conceptual design was conducted of the closed cycle system and the individual components to define physical characteristics and establish the system size and weight. Technology confirmation experimental demonstration programs were outlined to develop, evaluate, and demonstrate the technology base needed for this closed cycle GDL system.

77 FR 20059 - License Amendment To Increase the Maximum Reactor Power Level, Florida Power & Light Company...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-03

... surface evaporation. The canals are a closed recirculating loop that serves as the ultimate heat sink for...) for water discharges to an onsite closed-loop recirculation cooling canal system. The seasonal... to 90 [deg]F (21 [deg]C to 32 [deg]C). Additionally, the CCS water is hyper-saline (twice the...

Shock Position Control for Mode Transition in a Turbine Based Combined Cycle Engine Inlet Model

NASA Technical Reports Server (NTRS)

Csank, Jeffrey T.; Stueber, Thomas J.

2013-01-01

A dual flow-path inlet for a turbine based combined cycle (TBCC) propulsion system is to be tested in order to evaluate methodologies for performing a controlled inlet mode transition. Prior to experimental testing, simulation models are used to test, debug, and validate potential control algorithms which are designed to maintain shock position during inlet disturbances. One simulation package being used for testing is the High Mach Transient Engine Cycle Code simulation, known as HiTECC. This paper discusses the development of a mode transition schedule for the HiTECC simulation that is analogous to the development of inlet performance maps. Inlet performance maps, derived through experimental means, describe the performance and operability of the inlet as the splitter closes, switching power production from the turbine engine to the Dual Mode Scram Jet. With knowledge of the operability and performance tradeoffs, a closed loop system can be designed to optimize the performance of the inlet. This paper demonstrates the design of the closed loop control system and benefit with the implementation of a Proportional-Integral controller, an H-Infinity based controller, and a disturbance observer based controller; all of which avoid inlet unstart during a mode transition with a simulated disturbance that would lead to inlet unstart without closed loop control.

Phase III Integrated Water Recovery Testing at MSFC - Closed hygiene and potable loop test results and lesson learned

NASA Technical Reports Server (NTRS)

Holder, Donald W., Jr.; Bagdigian, Robert M.

1992-01-01

A series of tests has been conducted at the NASA Marshall Space Flight Center (MSFC) to evaluate the performance of a Space Station Freedom (SSF) pre-development water recovery system. Potable, hygiene, and urine reclamation subsystems were integrated with end-use equipment items and successfully operated for a total of 35 days, including 23 days in closed-loop mode with man-in-the-loop. Although several significant subsystem physical anomalies were encountered, reclaimed potable and hygiene water routinely met current SSF water quality specifications. This paper summarizes the test objectives, system design, test activities/protocols, significant results/anomalies, and major lessons learned.

Method for spinning up a three-axis controlled spacecraft

NASA Technical Reports Server (NTRS)

Vorlicek, Preston L. (Inventor)

1988-01-01

A three-axis controlled spacecraft (1), typically a satellite, is spun up about its roll axis (20) prior to firing a motor (2), i.e., a perigee kick motor, to achieve the requisite degree of angular momentum stiffness. Thrusters (21) for imparting rotation about the roll axis (20) are activated in open-loop fashion, typically at less than full duty cycle. Cross-axis torques induced by this rotational motion are compensated for by means of closed control loops for each of the pitch and yaw axes (30, 40, respectively). Each closed control loop combines a prebias torque (72) with torques (75, 74) representative of position and rate feedback information, respectively. A deadband (52) within each closed control loop can be widened during the spinup, to conserve fuel. Position feedback information (75) in each of the control loops is disabled upon saturation of the gyroscope associated with the roll axis (20).

The Life Cycle Evaluation Model of External Diseconomy of Open-loop Supply Chain

NASA Astrophysics Data System (ADS)

Liu, Qian; Hu, Tianjun

2017-08-01

In recent years, with the continuous deterioration of pollution, resource space is gradually narrowed, the number of waste items increased, people began to use the method of recycling on waste products to ease the pressure on the environment. This paper adopted the external diseconomy of open-loop supply chain as the research object and constructed the model by the life cycle evaluation method, comparative analysis through the case. This paper also concludes that the key to solving the problem is to realize the closed-loop supply chain and building reverse logistics system is of great significance.

CLOSED-LOOP TREATMENT OF ELECTROLYTIC AND ELECTROLESS NICKEL RINSE WATER BY POINT-OF-USE ION EXCHANGE: A CASE STUDY.

EPA Science Inventory

Closed-Loop Treatment of Electrolytic and Electroless Nickel Rinse Water by Point-Of-Use Ion Exchange: A Case Study.

Dave Szlag1, Joe Leonhardt2, Albert Foster1, Mike Goss1 and Paul Bolger1.
1 U.S. EPA, National Risk Management Research Laboratory, 26 W. M. L. King D...

Biological life support systems for a Mars mission planetary base: Problems and prospects

NASA Astrophysics Data System (ADS)

Tikhomirov, A. A.; Ushakova, S. A.; Kovaleva, N. P.; Lamaze, B.; Lobo, M.; Lasseur, Ch.

The study develops approaches to designing biological life support systems for the Mars mission - for the flight conditions and for a planetary base - using experience of the Institute of Biophysics of the Siberian Branch of the Russian Academy of Sciences (IBP SB RAS) with the Bios-3 system and ESA's experience with the MELISSA program. Variants of a BLSS based on using Chlorella and/or Spirulina and higher plants for the flight period of the Mars mission are analyzed. It is proposed constructing a BLSS with a closed-loop material cycle for gas and water and for part of human waste. A higher-plant-based BLSS with the mass exchange loop closed to various degrees is proposed for a Mars planetary base. Various versions of BLSS configuration and degree of closure of mass exchange are considered, depending on the duration of the Mars mission, the diet of the crew, and some other conditions. Special consideration is given to problems of reliability and sustainability of material cycling in BLSS, which are related to production of additional oxygen inside the system. Technologies of constructing BLSS of various configurations are proposed and substantiated. Reasons are given for using physicochemical methods in BLSS as secondary tools both during the flight and the stay on Mars.

Water cooling system for an air-breathing hypersonic test vehicle

NASA Technical Reports Server (NTRS)

Petley, Dennis H.; Dziedzic, William M.

1993-01-01

This study provides concepts for hypersonic experimental scramjet test vehicles which have low cost and low risk. Cryogenic hydrogen is used as the fuel and coolant. Secondary water cooling systems were designed. Three concepts are shown: an all hydrogen cooling system, a secondary open loop water cooled system, and a secondary closed loop water cooled system. The open loop concept uses high pressure helium (15,000 psi) to drive water through the cooling system while maintaining the pressure in the water tank. The water flows through the turbine side of the turbopump to pump hydrogen fuel. The water is then allowed to vent. In the closed loop concept high pressure, room temperature, compressed liquid water is circulated. In flight water pressure is limited to 6000 psi by venting some of the water. Water is circulated through cooling channels via an ejector which uses high pressure gas to drive a water jet. The cooling systems are presented along with finite difference steady-state and transient analysis results. The results from this study indicate that water used as a secondary coolant can be designed to increase experimental test time, produce minimum venting of fluid and reduce overall development cost.

The coal-fired gas turbine locomotive - A new look

NASA Technical Reports Server (NTRS)

Liddle, S. G.; Bonzo, B. B.; Purohit, G. P.

1983-01-01

Advances in turbomachine technology and novel methods of coal combustion may have made possible the development of a competitive coal fired gas turbine locomotive engine. Of the combustor, thermodynamic cycle, and turbine combinations presently assessed, an external combustion closed cycle regenerative gas turbine with a fluidized bed coal combustor is judged to be the best suited for locomotive requirements. Some merit is also discerned in external combustion open cycle regenerative systems and internal combustion open cycle regenerative gas turbine systems employing a coal gasifier. The choice of an open or closed cycle depends on the selection of a working fluid and the relative advantages of loop pressurization, with air being the most attractive closed cycle working fluid on the basis of cost.

Evaluation and control of microbial and chemical contamination in dialysis water plants of Italian nephrology wards.

PubMed

Totaro, M; Casini, B; Valentini, P; Miccoli, M; Giorgi, S; Porretta, A; Privitera, G; Lopalco, P L; Baggiani, A

2017-10-01

Patients receiving haemodialysis are exposed to a large volume of dialysis fluid. The Italian Society of Nephrology (ISN) has published guidelines and microbial quality standards on dialysis water (DW) and solutions to ensure patient safety. To identify microbial and chemical hazards, and evaluate the quality of disinfection treatment in DW plants. In 2015 and 2016, water networks and DW plants (closed loop and online monitors) of nine dialysis wards of Italian hospitals, hosting 162 dialysis beds overall, were sampled on a monthly basis to determine the parameters provided by ISN guidelines. Chlorinated drinking water was desalinated by reverse osmosis and distributed to the closed loop which feeds all online monitors. Disinfection with peracetic acid was performed in all DW plants on a monthly basis. Over the 24-month study period, seven out of nine DW plants (78%) recorded negative results for all investigated parameters. Closed loop contamination with Burkholderia cepacia was detected in a DW plant from January 2015 to March 2015. Pseudomonas aeruginosa was isolated from March 2016 to May 2016 in the closed loop of another DW plant. These microbial contaminations were eradicated by shock disinfection with sodium hypochlorite and peracetic acid, followed by water flushing. These results highlight the importance of chemical and physical methods of DW disinfection. The maintenance of control measures in water plants hosted in dialysis wards ensures a microbial risk reduction for all dialysis patients. Copyright © 2017 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.

Effects of backlash and dead band on temperature control of the primary loop of a conceptual nuclear Brayton space powerplant

NASA Technical Reports Server (NTRS)

Petrick, E. J.

1973-01-01

An analytical study was made of the stability of a closed-loop liquid-lithium temperature control of the primary loop of a conceptual nuclear Brayton space powerplant. The operating point was varied from 20 to 120 percent of design. A describing-function technique was used to evaluate the effects of temperature dead band and control coupling backlash. From the system investigation, it was predicted that a limit cycle will not exist with a temperature dead band, but a limit cycle will not exist when backlash is present. The results compare favorably with a digital computer simulation.

Closed-loop endo-atmospheric ascent guidance for reusable launch vehicle

NASA Astrophysics Data System (ADS)

Sun, Hongsheng

This dissertation focuses on the development of a closed-loop endo-atmospheric ascent guidance algorithm for the 2nd generation reusable launch vehicle. Special attention has been given to the issues that impact on viability, complexity and reliability in on-board implementation. The algorithm is called once every guidance update cycle to recalculate the optimal solution based on the current flight condition, taking into account atmospheric effects and path constraints. This is different from traditional ascent guidance algorithms which operate in a simple open-loop mode inside atmosphere, and later switch to a closed-loop vacuum ascent guidance scheme. The classical finite difference method is shown to be well suited for fast solution of the constrained optimal three-dimensional ascent problem. The initial guesses for the solutions are generated using an analytical vacuum optimal ascent guidance algorithm. Homotopy method is employed to gradually introduce the aerodynamic forces to generate the optimal solution from the optimal vacuum solution. The vehicle chosen for this study is the Lockheed Martin X-33 lifting-body reusable launch vehicle. To verify the algorithm presented in this dissertation, a series of open-loop and closed-loop tests are performed for three different missions. Wind effects are also studied in the closed-loop simulations. For comparison, the solutions for the same missions are also obtained by two independent optimization softwares. The results clearly establish the feasibility of closed-loop endo-atmospheric ascent guidance of rocket-powered launch vehicles. ATO cases are also tested to assess the adaptability of the algorithm to autonomously incorporate the abort modes.

Flight Engineer Donald R. Pettit looks closely at Sodium Chloride within a 50-millimeter metal loop

NASA Image and Video Library

2003-03-12

ISS006-E-39142 (12 March 2003) --- Astronaut Donald R. Pettit, Expedition Six NASA ISS science officer, looks closely at a water bubble within a 50-millimeter metal loop. The experiment took place in the Destiny laboratory on the International Space Station (ISS).

Experimental investigation on thermal performance of a closed loop pulsating heat pipe (CLPHP) using methanol and distilled water at different filling ratios

NASA Astrophysics Data System (ADS)

Rahman, Md. Lutfor; Swarna, Anindita Dhar; Ahmed, Syed Nasif Uddin; Perven, Sanjida; Ali, Mohammad

2016-07-01

Pulsating Heat Pipes, the new two-phase heat transfer devices, with no counter current flow between liquid and vapor have become a modern topic for research in the field of thermal management. This paper focuses on the performance of methanol and distilled water as working fluid in a closed loop pulsating heat pipe (CLPHP). This performances are compared in terms of thermal resistance, heat transfer co-efficient, and evaporator and condenser wall temperature with variable heat inputs. Methanol and Distilled water are selected for their lower surface tension, dynamic viscosity and sensible heat. A closed loop PHP made of copper with 2mm ID and 2.5mm OD having total 8 loops are supplied with power input varied from 10W to 60W. During the experiment the PHP is kept vertical, while the filling ratio (FR) is increased gradually from 40% to 70% with 10% increment. The optimum filling ratio for a minimum thermal resistance is found to be 60% and 40% for distilled water and methanol respectively and methanol is found to be the better working fluid compared to distilled water in terms of its lower thermal resistance and higher heat transfer coefficient.

Cycle-averaged dynamics of a periodically driven, closed-loop circulation model

NASA Technical Reports Server (NTRS)

Heldt, T.; Chang, J. L.; Chen, J. J. S.; Verghese, G. C.; Mark, R. G.

2005-01-01

Time-varying elastance models have been used extensively in the past to simulate the pulsatile nature of cardiovascular waveforms. Frequently, however, one is interested in dynamics that occur over longer time scales, in which case a detailed simulation of each cardiac contraction becomes computationally burdensome. In this paper, we apply circuit-averaging techniques to a periodically driven, closed-loop, three-compartment recirculation model. The resultant cycle-averaged model is linear and time invariant, and greatly reduces the computational burden. It is also amenable to systematic order reduction methods that lead to further efficiencies. Despite its simplicity, the averaged model captures the dynamics relevant to the representation of a range of cardiovascular reflex mechanisms. c2004 Elsevier Ltd. All rights reserved.

Conceptual design of a thermal control system for an inflatable lunar habitat module

NASA Technical Reports Server (NTRS)

Gadkari, Ketan; Goyal, Sanjay K.; Vanniasinkam, Joseph

1991-01-01

NASA is considering the establishment of a manned lunar base within the next few decades. To house and protect the crew from the harsh lunar environment, a habitat is required. A proposed habitat is an spherical, inflatable module. Heat generated in the module must be rejected to maintain a temperature suitable for human habitation. This report presents a conceptual design of a thermal control system for an inflatable lunar module. The design solution includes heat acquisition, heat transport, and heat rejection subsystems. The report discusses alternative designs and design solutions for each of the three subsystems mentioned above. Alternative subsystems for heat acquisition include a single water-loop, a single air-loop, and a double water-loop. The vapor compression cycle, vapor absorption cycle, and metal hydride absorption cycle are the three alternative transport subsystems. Alternative rejection subsystems include flat plate radiators, the liquid droplet radiator, and reflux boiler radiators. Feasibility studies on alternatives of each subsystem showed that the single water-loop, the vapor compression cycle, and the reflux boiler radiator were the most feasible alternatives. The design team combined the three subsystems to come up with an overall system design. Methods of controlling the system to adapt it for varying conditions within the module and in the environment are presented. Finally, the report gives conclusions and recommendations for further study of thermal control systems for lunar applications.

Industrial wastewater re-use: closure of water cycle in the main water consuming industries--the example of paper mills.

PubMed

Mauchauffee, S; Denieul, M-P; Coste, M

2012-01-01

Paper mill, chemistry, textile and food processing industries are high water consumers. Within the framework of the European project Aquafit4Use, the possibility to close the on-site water loop is studied. The aim is to find new technologies or innovative treatment trains to produce water that is 'fit for use' in the industrial process; an example of a paper mill is given. Laboratory-scale tests on nine technologies were carried out to determine the best suitable treatment train: anaerobic process (already on site) --> aerobic process (already on site) --> Flexible Fibre Filter Module --> softening --> nanofiltration --> evapoconcentration or ozonation on nanofiltration (NF) concentrate. This treatment train is currently compared on site at pilot scale to another treatment train including some modifications on the existing on-site biological treatment: anaerobic process --> softening --> membrane bioreactor --> nanofiltration --> evapoconcentration or ozonation of NF concentrate.

Radiology reporting: a closed-loop cycle from order entry to results communication.

PubMed

Weiss, David L; Kim, Woojin; Branstetter, Barton F; Prevedello, Luciano M

2014-12-01

With the increasing prevalence of PACS over the past decade, face-to-face image review among health care providers has become a rarity. This change has resulted in increasing dependence on fast and accurate communication in radiology. Turnaround time expectations are now conveyed in minutes rather than hours or even days. Ideal modern radiology communication is a closed-loop cycle with multiple interoperable applications contributing to the final product. The cycle starts with physician order entry, now often performed through the electronic medical record, with clinical decision support to ensure that the most effective imaging study is ordered. Radiology reports are now almost all in electronic format. The majority are produced using speech recognition systems. Optimization of this software use can alleviate some, if not all, of the inherent user inefficiencies in this type of reporting. Integrated third-party software applications that provide data mining capability are extremely helpful in both academic and clinical settings. The closed-loop ends with automated communication of imaging results. Software products for this purpose should facilitate use of levels of alert, automated escalation to providers, and recording of audit trails of reports received. The multiple components of reporting should be completely interoperable with each other, as well as with the PACS, the RIS, and the electronic medical record. This integration will maximize radiologist efficiency and minimize the possibility of communication error. Copyright © 2014. Published by Elsevier Inc.

Closed Loop Experiment Manager (CLEM)-An Open and Inexpensive Solution for Multichannel Electrophysiological Recordings and Closed Loop Experiments.

PubMed

Hazan, Hananel; Ziv, Noam E

2017-01-01

There is growing need for multichannel electrophysiological systems that record from and interact with neuronal systems in near real-time. Such systems are needed, for example, for closed loop, multichannel electrophysiological/optogenetic experimentation in vivo and in a variety of other neuronal preparations, or for developing and testing neuro-prosthetic devices, to name a few. Furthermore, there is a need for such systems to be inexpensive, reliable, user friendly, easy to set-up, open and expandable, and possess long life cycles in face of rapidly changing computing environments. Finally, they should provide powerful, yet reasonably easy to implement facilities for developing closed-loop protocols for interacting with neuronal systems. Here, we survey commercial and open source systems that address these needs to varying degrees. We then present our own solution, which we refer to as Closed Loop Experiments Manager (CLEM). CLEM is an open source, soft real-time, Microsoft Windows desktop application that is based on a single generic personal computer (PC) and an inexpensive, general-purpose data acquisition board. CLEM provides a fully functional, user-friendly graphical interface, possesses facilities for recording, presenting and logging electrophysiological data from up to 64 analog channels, and facilities for controlling external devices, such as stimulators, through digital and analog interfaces. Importantly, it includes facilities for running closed-loop protocols written in any programming language that can generate dynamic link libraries (DLLs). We describe the application, its architecture and facilities. We then demonstrate, using networks of cortical neurons growing on multielectrode arrays (MEA) that despite its reliance on generic hardware, its performance is appropriate for flexible, closed-loop experimentation at the neuronal network level.

Closed Loop Experiment Manager (CLEM)—An Open and Inexpensive Solution for Multichannel Electrophysiological Recordings and Closed Loop Experiments

PubMed Central

Hazan, Hananel; Ziv, Noam E.

2017-01-01

There is growing need for multichannel electrophysiological systems that record from and interact with neuronal systems in near real-time. Such systems are needed, for example, for closed loop, multichannel electrophysiological/optogenetic experimentation in vivo and in a variety of other neuronal preparations, or for developing and testing neuro-prosthetic devices, to name a few. Furthermore, there is a need for such systems to be inexpensive, reliable, user friendly, easy to set-up, open and expandable, and possess long life cycles in face of rapidly changing computing environments. Finally, they should provide powerful, yet reasonably easy to implement facilities for developing closed-loop protocols for interacting with neuronal systems. Here, we survey commercial and open source systems that address these needs to varying degrees. We then present our own solution, which we refer to as Closed Loop Experiments Manager (CLEM). CLEM is an open source, soft real-time, Microsoft Windows desktop application that is based on a single generic personal computer (PC) and an inexpensive, general-purpose data acquisition board. CLEM provides a fully functional, user-friendly graphical interface, possesses facilities for recording, presenting and logging electrophysiological data from up to 64 analog channels, and facilities for controlling external devices, such as stimulators, through digital and analog interfaces. Importantly, it includes facilities for running closed-loop protocols written in any programming language that can generate dynamic link libraries (DLLs). We describe the application, its architecture and facilities. We then demonstrate, using networks of cortical neurons growing on multielectrode arrays (MEA) that despite its reliance on generic hardware, its performance is appropriate for flexible, closed-loop experimentation at the neuronal network level. PMID:29093659

Comparison between solar utilization of a closed microalgae-based bio-loop and that of a stand-alone photovoltaic system.

PubMed

Jin, Qiang; Chen, Lei; Li, Aimin; Liu, Fuqiang; Long, Chao; Shan, Aidang; Borthwick, Alistair G L

2015-05-01

This study compared the solar energy utilization of a closed microalgae-based bio-loop for energy efficient production of biogas with fertilizer recovery against that of a stand-alone photovoltaic (PV) system. The comparison was made from the perspective of broad life cycle assessment, simultaneously taking exergy to be the functional unit. The results indicated that the bio-loop was more environmentally competitive than an equivalent stand-alone PV system, but had higher economic cost due to high energy consumption during the operational phase. To fix the problem, a patented, interior pressurization scheduling method was used to operate the bio-loop, with microalgae and aerobic bacterial placed together in the same reactor. As a result, the overall environmental impact and total investment were respectively reduced by more than 75% and 84%, a vast improvement on the bio-loop. Copyright © 2014 Elsevier Ltd. All rights reserved.

Dynamics of the active site loops in catalyzing aminoacylation reaction in seryl and histidyl tRNA synthetases.

PubMed

Dutta, Saheb; Kundu, Soumya; Saha, Amrita; Nandi, Nilashis

2018-03-01

Aminoacylation reaction is the first step of protein biosynthesis. The catalytic reorganization at the active site of aminoacyl tRNA synthetases (aaRSs) is driven by the loop motions. There remain lacunae of understanding concerning the catalytic loop dynamics in aaRSs. We analyzed the functional loop dynamics in seryl tRNA synthetase from Methanopyrus kandleri ( mk SerRS) and histidyl tRNA synthetases from Thermus thermophilus ( tt HisRS), respectively, using molecular dynamics. Results confirm that the motif 2 loop and other active site loops are flexible spots within the catalytic domain. Catalytic residues of the loops form a network of interaction with the substrates to form a reactive state. The loops undergo transitions between closed state and open state and the relaxation of the constituent residues occurs in femtosecond to nanosecond time scale. Order parameters are higher for constituent catalytic residues which form a specific network of interaction with the substrates to form a reactive state compared to the Gly residues within the loop. The development of interaction is supported from mutation studies where the catalytic domain with mutated loop exhibits unfavorable binding energy with the substrates. During the open-close motion of the loops, the catalytic residues make relaxation by ultrafast librational motion as well as fast diffusive motion and subsequently relax rather slowly via slower diffusive motion. The Gly residues act as a hinge to facilitate the loop closing and opening by their faster relaxation behavior. The role of bound water is analyzed by comparing implicit solvent-based and explicit solvent-based simulations. Loops fail to form catalytically competent geometry in absence of water. The present result, for the first time reveals the nature of the active site loop dynamics in aaRS and their influence on catalysis.

Louisiana offshore terminal authority environmental monitoring

DOT National Transportation Integrated Search

2002-09-01

The current Louisiana Offshore Oil Port (LOOP) monitoring program includes seasonal monitoring of aquatic and marine resources, sediment composition, and water quality on a five-year cycle. These data provide an update to the existing long-term LOOP ...

Inventory decision in a closed-loop supply chain with inspection, sorting, and waste disposal

NASA Astrophysics Data System (ADS)

Dwicahyani, A. R.; Jauhari, W. A.; Kurdhi, N. A.

2016-02-01

The study of returned item inventory management in a closed-loop supply chain system has become an important issue in recent years. So far, investigations about inventory decision making in a closed-loop supply chain system have been confined to traditional forward and reverse oriented material flow supply chain. In this study, we propose an integrated inventory model consisting a supplier, a manufacturer, and a retailer where the manufacturer inspects all of the returned items collected from the customers and classifies them as recoverable or waste. Returned items that recovered through the remanufacturing process and the newly manufactured products are then used to meet the demand of the retailer. However, some recovered items which are not comparable to the ones in quality, classified as refurbished items, are sold to a secondary market at a reduced price. This study also suggests that the flow of returned items is controlled by a decision variable, namely an acceptance quality level of recoverable item in the system. We apply multiple remanufacturing cycle and multiple production cycle policy to the proposed model and give the corresponding iterative procedure to determine the optimal solutions. Further, numerical examples are presented for illustrative purpose.

Integrated design of cryogenic refrigerator and liquid-nitrogen circulation loop for HTS cable

NASA Astrophysics Data System (ADS)

Chang, Ho-Myung; Ryu, Ki Nam; Yang, Hyung Suk

2016-12-01

A new concept of cryogenic cooling system is proposed and investigated for application to long-length HTS cables. One of major obstacles to the cable length of 1 km or longer is the difficulty in circulating liquid nitrogen (LN) along the cables, since the temperature rise and pressure drop of LN flow could be excessively large. This study attempts a breakthrough by integrating the refrigerator with the LN circulation loop in order to eliminate the cryogenic LN pumps, and generate a large LN flow with the power of compressors at ambient temperature. A variety of thermodynamic structures are investigated on standard and modified Claude cycles, where nitrogen is used as refrigerant and the LN circulation loop is included as part of the closed cycle. Four proposed cycles are fully analyzed and optimized with a process simulator (Aspen HYSYS) to evaluate the FOM (figure of merit) and examine the feasibility. The modified dual-pressure cycle cooled with expander stream is recommended for long HTS cables.

High-Performance Computing Data Center Cooling System Energy Efficiency |

Science.gov Websites

approaches involve a cooling distribution unit (CDU) (2), which interfaces with the facility cooling loop and to the energy recovery water (ERW) loop (5), which is a closed-loop system. There are three heat rejection options for this IT load: When possible, heat energy from the energy recovery loop is transferred

Advancing the Food-Energy-Water Nexus: Closing Nutrient Loops in Arid River Corridors.

PubMed

Mortensen, Jacob G; González-Pinzón, Ricardo; Dahm, Clifford N; Wang, Jingjing; Zeglin, Lydia H; Van Horn, David J

2016-08-16

Closing nutrient loops in terrestrial and aquatic ecosystems is integral to achieve resource security in the food-energy-water (FEW) nexus. We performed multiyear (2005-2008), monthly sampling of instream dissolved inorganic nutrient concentrations (NH4-N, NO3-N, soluble reactive phosphorus-SRP) along a ∼ 300-km arid-land river (Rio Grande, NM) and generated nutrient budgets to investigate how the net source/sink behavior of wastewater and irrigated agriculture can be holistically managed to improve water quality and close nutrient loops. Treated wastewater on average contributed over 90% of the instream dissolved inorganic nutrients (101 kg/day NH4-N, 1097 kg/day NO3-N, 656 kg/day SRP). During growing seasons, the irrigation network downstream of wastewater outfalls retained on average 37% of NO3-N and 45% of SRP inputs, with maximum retention exceeding 60% and 80% of NO3-N and SRP inputs, respectively. Accurate quantification of NH4-N retention was hindered by low loading and high variability. Nutrient retention in the irrigation network and instream processes together limited downstream export during growing seasons, with total retention of 33-99% of NO3-N inputs and 45-99% of SRP inputs. From our synoptic analysis, we identify trade-offs associated with wastewater reuse for agriculture within the scope of the FEW nexus and propose strategies for closing nutrient loops in arid-land rivers.

Role of the Iron Axial Ligands of Heme Carrier HasA in Heme Uptake and Release*

PubMed Central

Caillet-Saguy, Célia; Piccioli, Mario; Turano, Paola; Lukat-Rodgers, Gudrun; Wolff, Nicolas; Rodgers, Kenton R.; Izadi-Pruneyre, Nadia; Delepierre, Muriel; Lecroisey, Anne

2012-01-01

The hemophore protein HasA from Serratia marcescens cycles between two states as follows: the heme-bound holoprotein, which functions as a carrier of the metal cofactor toward the membrane receptor HasR, and the heme-free apoprotein fishing for new porphyrin to be taken up after the heme has been delivered to HasR. Holo- and apo-forms differ for the conformation of the two loops L1 and L2, which provide the axial ligands of the iron through His32 and Tyr75, respectively. In the apo-form, loop L1 protrudes toward the solvent far away from loop L2; in the holoprotein, closing of the loops on the heme occurs upon establishment of the two axial coordination bonds. We have established that the two variants obtained via single point mutations of either axial ligand (namely H32A and Y75A) are both in the closed conformation. The presence of the heme and one out of two axial ligands is sufficient to establish a link between L1 and L2, thanks to the presence of coordinating solvent molecules. The latter are stabilized in the iron coordination environment by H-bond interactions with surrounding protein residues. The presence of such a water molecule in both variants is revealed here through a set of different spectroscopic techniques. Previous studies had shown that heme release and uptake processes occur via intermediate states characterized by a Tyr75-iron-bound form with open conformation of loop L1. Here, we demonstrate that these states do not naturally occur in the free protein but can only be driven by the interaction with the partner proteins. PMID:22700962

Thermal control systems for low-temperature heat rejection on a lunar base

NASA Technical Reports Server (NTRS)

Sridhar, K. R.; Gottmann, Matthias

1992-01-01

In this report, Rankine-cycle heat pumps and absorption heat pumps (ammonia-water and lithium bromide-water) have been analyzed and optimized for a lunar base cooling load of 100 kW. For the Rankine cycle, a search of several commonly used commercial refrigerants provided R11 and R717 as possible working fluids. Hence, the Rankine-cycle analysis has been performed for both R11 and R717. Two different configurations were considered for the system--one in which the heat pump is directly connected to the rejection loop and another in which a heat exchanger connects the heat pump to the rejection loop. For a marginal increase in mass, the decoupling of the rejection loop and the radiator from the heat pump provides greater reliability of the system and better control. Hence, the decoupled system is the configuration of choice. The optimal TCS mass for a 100 kW cooling load at 270 K was 5940 kg at a radiator temperature of 362 K. R11 was the working fluid in the heat pump, and R717 was the transport fluid in the rejection loop. Two TCS's based on an absorption-cycle heat pump were considered, one with an ammonia-water mixture and the other with a lithium bromide-water mixture as the working fluid. A complete cycle analysis was performed for these systems. The system components were approximated as heat exchangers with no internal pressure drop for the mass estimate. This simple approach underpredicts the mass of the systems, but is a good 'optimistic' first approximation to the TCS mass in the absence of reliable component mass data. The mass estimates of the two systems reveal that, in spite of this optimistic estimate, the absorption heat pumps are not competitive with the Rankine-cycle heat pumps. Future work at the systems level will involve similar analyses for the Brayton- and Stirling-cycle heat pumps. The analyses will also consider the operation of the pump under partial-load conditions. On the component level, a capillary evaporator will be designed, built, and tested in order to investigate its suitability in lunar base TCS and microgravity two-phase applications.

Advanced Multi-Effect Distillation System for Desalination Using Waste Heat fromGas Brayton Cycles

DOE Office of Scientific and Technical Information (OSTI.GOV)

Haihua Zhao; Per F. Peterson

2012-10-01

Generation IV high temperature reactor systems use closed gas Brayton Cycles to realize high thermal efficiency in the range of 40% to 60%. The waste heat is removed through coolers by water at substantially greater average temperature than in conventional Rankine steam cycles. This paper introduces an innovative Advanced Multi-Effect Distillation (AMED) design that can enable the production of substantial quantities of low-cost desalinated water using waste heat from closed gas Brayton cycles. A reference AMED design configuration, optimization models, and simplified economics analysis are presented. By using an AMED distillation system the waste heat from closed gas Brayton cyclesmore » can be fully utilized to desalinate brackish water and seawater without affecting the cycle thermal efficiency. Analysis shows that cogeneration of electricity and desalinated water can increase net revenues for several Brayton cycles while generating large quantities of potable water. The AMED combining with closed gas Brayton cycles could significantly improve the sustainability and economics of Generation IV high temperature reactors.« less

Performance of Water Recirculation Loop Maintenance Components for the Advanced Spacesuit Water Membrane Evaporator

NASA Technical Reports Server (NTRS)

Rector, Tony; Peyton, Barbara M.; Steele, John W.; Makinen, Janice; Bue, Grant C.; Campbell, Colin

2014-01-01

Water loop maintenance components to maintain the water quality of the Advanced Spacesuit Water Membrane Evaporation (SWME) water recirculation loop have undergone a comparative performance evaluation with a second SWME water recirculation loop with no water quality maintenance. Results show the benefits of periodic water maintenance. The SWME is a heat rejection device under development at the NASA Johnson Space Center to perform thermal control for advanced spacesuits. One advantage to this technology is the potential for a significantly greater degree of tolerance to contamination when compared to the existing Sublimator technology. The driver for the evaluation of water recirculation maintenance components was to further enhance this advantage through the leveraging of fluid loop management lessons learned from the International Space Station (ISS). A bed design that was developed for a UTAS military application, and considered for a potential ISS application with the Urine Processor Assembly, provided a low pressure drop means for water maintenance in a recirculation loop. The bed design is coupled with high capacity ion exchange resins, organic adsorbents, and a cyclic methodology developed for the Extravehicular Mobility Unit (EMU) Transport Water loop. The maintenance cycle included the use of a biocide delivery component developed for ISS to introduce a biocide in a microgravity compatible manner for the Internal Active Thermal Control System (IATCS). The leveraging of these water maintenance technologies to the SWME recirculation loop is a unique demonstration of applying the valuable lessons learned on the ISS to the next generation of manned spaceflight Environmental Control and Life Support System (ECLSS) hardware.

Performance of Water Recirculation Loop Maintentance Components for the Advanced Spacesuit Water Membrane Evaporator

NASA Technical Reports Server (NTRS)

Rector, Tony; Peyton, Barbara; Steele, John W.; Bue, Grant C.; Campbell, Colin; Makinen, Janice

2014-01-01

Water loop maintenance components to maintain the water quality of the Advanced Spacesuit Water Membrane Evaporation (SWME) water recirculation loop have undergone a comparative performance evaluation with a second SWME water recirculation loop with no water quality maintenance. Results show the benefits of periodic water maintenance. The SWME is a heat rejection device under development at the NASA Johnson Space Center to perform thermal control for advanced spacesuits. One advantage to this technology is the potential for a significantly greater degree of tolerance to contamination when compared to the existing Sublimator technology. The driver for the evaluation of water recirculation maintenance components was to further enhance this advantage through the leveraging of fluid loop management lessonslearned from the International Space Station (ISS). A bed design that was developed for a UTAS military application, and considered for a potential ISS application with the Urine Processor Assembly, provided a low pressure drop means for water maintenance in a recirculation loop. The bed design is coupled with high capacity ion exchange resins, organic adsorbents, and a cyclic methodology developed for the Extravehicular Mobility Unit (EMU) Transport Water loop. The maintenance cycle included the use of a biocide delivery component developed for ISS to introduce a biocide in a microgravity-compatible manner for the Internal Active Thermal Control System (IATCS). The leveraging of these water maintenance technologies to the SWME recirculation loop is a unique demonstration of applying the valuable lessons learned on the ISS to the next generation of manned spaceflight Environmental Control and Life Support System (ECLSS) hardware.

Perspectives for a better understanding of the metabolic integration of photorespiration within a complex plant primary metabolism network

USDA-ARS?s Scientific Manuscript database

Photorespiration is an important high flux metabolic pathway that is found in all oxygen-producing photosynthetic organisms. It is often viewed as a closed loop that recycles carbon to fuel the Calvin cycle. However, the photorespiratory cycle is known to interact with several primary metabolic path...

Close-loop Dynamic Stall Control on a Pitching Airfoil

NASA Astrophysics Data System (ADS)

Giles, Ian; Corke, Thomas

2017-11-01

A closed-loop control scheme utilizing a plasma actuator to control dynamic stall is presented. The plasma actuator is located at the leading-edge of a pitching airfoil. It initially pulses at an unsteady frequency that perturbs the boundary layer flow over the suction surface of the airfoil. As the airfoil approaches and enters stall, the amplification of the unsteady disturbance is detected by an onboard pressure sensor also located near the leading edge. Once detected, the actuator is switched to a higher voltage control state that in static airfoil experiments would reattach the flow. The threshold level of the detection is a parameter in the control scheme. Three stall regimes were examined: light, medium, and deep stall, that were defined by their stall penetration angles. The results showed that in general, the closed-loop control scheme was effective at controlling dynamic stall. The cycle-integrated lift improved in all cases, and increased by as much as 15% at the lowest stall penetration angle. As important, the cycle-integrated aerodynamic damping coefficient also increased in all cases, and was made to be positive at the light stall regime where it traditionally is negative. The latter is important in applications where negative damping can lead to stall flutter.

Performance of Water Recirculation Loop Maintenance Components for the Advanced Spacesuit Water Membrane Evaporator

NASA Technical Reports Server (NTRS)

Rector, Tony; Peyton, Barbara M.; Steele, John W.; Makinen, Janice; Bue, Grant C.; Campbell, Colin

2014-01-01

Water loop maintenance components to maintain the water quality of the Advanced Spacesuit Water Membrane Evaporation (SWME) water recirculation loop have undergone a comparative performance evaluation with a recirculating control loop which had no water quality maintenance. Results show that periodic water maintenance can improve performance of the SWME. The SWME is a heat rejection device under development at the NASA Johnson Space Center to perform thermal control for advanced spacesuits. One advantage of this technology is the potential for a significantly greater degree of tolerance to contamination when compared to the existing sublimator technology. The driver for the evaluation of water recirculation maintenance components was to enhance the robustness of the SWME through the leveraging of fluid loop management lessons learned from the International Space Station (ISS). A patented bed design that was developed for a United Technologies Aerospace System military application provided a low pressure drop means for water maintenance in the SWME recirculation loop. The bed design is coupled with high capacity ion exchange resins, organic adsorbents, and a cyclic methodology developed for the Extravehicular Mobility Unit (EMU) Transport Water loop. The maintenance cycle included the use of a biocide delivery component developed for the ISS to introduce a biocide in a microgravity compatible manner for the Internal Active Thermal Control System (IATCS). The leveraging of these water maintenance technologies to the SWME recirculation loop is a unique demonstration of applying the valuable lessons learned on the ISS to the next generation of manned spaceflight Environmental Control and Life Support System (ECLSS) hardware.

An analysis of hydrogen production via closed-cycle schemes. [thermochemical processings from water

NASA Technical Reports Server (NTRS)

Chao, R. E.; Cox, K. E.

1975-01-01

A thermodynamic analysis and state-of-the-art review of three basic schemes for production of hydrogen from water: electrolysis, thermal water-splitting, and multi-step thermochemical closed cycles is presented. Criteria for work-saving thermochemical closed-cycle processes are established, and several schemes are reviewed in light of such criteria. An economic analysis is also presented in the context of energy costs.

76 FR 71379 - Florida Power & Light Company, Turkey Point, Units 3 and 4; Draft Environmental Assessment and...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-17

... recirculating loop that serves as the ultimate heat sink for PTN Units 3 and 4. The CCS is operated under an...) permit from the FDEP (NPDES permit number FL0001562) for water discharges to an onsite closed-loop..., the CCS water is hyper-saline (twice the salinity of Biscayne Bay) with seasonal variations ranging...

Closed-loop control of zebrafish response using a bioinspired robotic-fish in a preference test

PubMed Central

Kopman, Vladislav; Laut, Jeffrey; Polverino, Giovanni; Porfiri, Maurizio

2013-01-01

In this paper, we study the response of zebrafish to a robotic-fish whose morphology and colour pattern are inspired by zebrafish. Experiments are conducted in a three-chambered instrumented water tank where a robotic-fish is juxtaposed with an empty compartment, and the preference of live subjects is scored as the mean time spent in the vicinity of the tank's two lateral sides. The tail-beating of the robotic-fish is controlled in real-time based on feedback from fish motion to explore a spectrum of closed-loop systems, including proportional and integral controllers. Closed-loop control systems are complemented by open-loop strategies, wherein the tail-beat of the robotic-fish is independent of the fish motion. The preference space and the locomotory patterns of fish for each experimental condition are analysed and compared to understand the influence of real-time closed-loop control on zebrafish response. The results of this study show that zebrafish respond differently to the pattern of tail-beating motion executed by the robotic-fish. Specifically, the preference and behaviour of zebrafish depend on whether the robotic-fish tail-beating frequency is controlled as a function of fish motion and how such closed-loop control is implemented. PMID:23152102

A theory of how active behavior stabilises neural activity: Neural gain modulation by closed-loop environmental feedback

PubMed Central

2018-01-01

During active behaviours like running, swimming, whisking or sniffing, motor actions shape sensory input and sensory percepts guide future motor commands. Ongoing cycles of sensory and motor processing constitute a closed-loop feedback system which is central to motor control and, it has been argued, for perceptual processes. This closed-loop feedback is mediated by brainwide neural circuits but how the presence of feedback signals impacts on the dynamics and function of neurons is not well understood. Here we present a simple theory suggesting that closed-loop feedback between the brain/body/environment can modulate neural gain and, consequently, change endogenous neural fluctuations and responses to sensory input. We support this theory with modeling and data analysis in two vertebrate systems. First, in a model of rodent whisking we show that negative feedback mediated by whisking vibrissa can suppress coherent neural fluctuations and neural responses to sensory input in the barrel cortex. We argue this suppression provides an appealing account of a brain state transition (a marked change in global brain activity) coincident with the onset of whisking in rodents. Moreover, this mechanism suggests a novel signal detection mechanism that selectively accentuates active, rather than passive, whisker touch signals. This mechanism is consistent with a predictive coding strategy that is sensitive to the consequences of motor actions rather than the difference between the predicted and actual sensory input. We further support the theory by re-analysing previously published two-photon data recorded in zebrafish larvae performing closed-loop optomotor behaviour in a virtual swim simulator. We show, as predicted by this theory, that the degree to which each cell contributes in linking sensory and motor signals well explains how much its neural fluctuations are suppressed by closed-loop optomotor behaviour. More generally we argue that our results demonstrate the dependence of neural fluctuations, across the brain, on closed-loop brain/body/environment interactions strongly supporting the idea that brain function cannot be fully understood through open-loop approaches alone. PMID:29342146

A theory of how active behavior stabilises neural activity: Neural gain modulation by closed-loop environmental feedback.

PubMed

Buckley, Christopher L; Toyoizumi, Taro

2018-01-01

During active behaviours like running, swimming, whisking or sniffing, motor actions shape sensory input and sensory percepts guide future motor commands. Ongoing cycles of sensory and motor processing constitute a closed-loop feedback system which is central to motor control and, it has been argued, for perceptual processes. This closed-loop feedback is mediated by brainwide neural circuits but how the presence of feedback signals impacts on the dynamics and function of neurons is not well understood. Here we present a simple theory suggesting that closed-loop feedback between the brain/body/environment can modulate neural gain and, consequently, change endogenous neural fluctuations and responses to sensory input. We support this theory with modeling and data analysis in two vertebrate systems. First, in a model of rodent whisking we show that negative feedback mediated by whisking vibrissa can suppress coherent neural fluctuations and neural responses to sensory input in the barrel cortex. We argue this suppression provides an appealing account of a brain state transition (a marked change in global brain activity) coincident with the onset of whisking in rodents. Moreover, this mechanism suggests a novel signal detection mechanism that selectively accentuates active, rather than passive, whisker touch signals. This mechanism is consistent with a predictive coding strategy that is sensitive to the consequences of motor actions rather than the difference between the predicted and actual sensory input. We further support the theory by re-analysing previously published two-photon data recorded in zebrafish larvae performing closed-loop optomotor behaviour in a virtual swim simulator. We show, as predicted by this theory, that the degree to which each cell contributes in linking sensory and motor signals well explains how much its neural fluctuations are suppressed by closed-loop optomotor behaviour. More generally we argue that our results demonstrate the dependence of neural fluctuations, across the brain, on closed-loop brain/body/environment interactions strongly supporting the idea that brain function cannot be fully understood through open-loop approaches alone.

Fermentation as a first step in carbon and nutrient recovery in regenerative life support systems

NASA Astrophysics Data System (ADS)

Luther, Amanda; Lasseur, Christophe; Rebeyre, Pierre; Clauwaert, Peter; Rabaey, Korneel; Ronsse, Frederik; Zhang, Dong Dong; López Barreiro, Diego; Prins, Wolter

2016-07-01

Long term manned space missions, such as the establishment of a base on Mars, will require a regenerative means of supplying the basic resources (i.e., food, water, oxygen) necessary to support human life. The MELiSSA-loop is a closed loop compartmentalized artificial aquatic ecosystem designed to recover water, carbon, and nutrients from solid organic wastes (e.g., inedible food waste and feces) for the regeneration of food and oxygen for humans. The first step in this loop is a strictly anaerobic fermentation unit operated as a membrane bioreactor. In this step the aim is to maximize the hydrolysis of complex organic compounds into simple molecules (CO2, ammonia, volatile fatty acids, …) which can be consumed by plants and bacteria downstream to produce food again. Optimal steady state fermentation of a standardized homogeneous mixture of beets, lettuce, wheat straw, toilet paper, feces, and water was demonstrated to recover approximately 50% of the influent carbon as soluble organics in the effluent through anaerobic fermentation. Approximately 10% of the influent COD was converted to CO2, with the remaining ~40% retained as a mixture of undigested solids and biomass. Approximately 50% of the influent nitrogen was recovered in the effluent, 97% of which was in the form of ammonia. Similar results have been obtained at both lab and pilot scale. With only 10% of the carbon driven to CO2 through this fermentation, a major challenge at this moment for the MELiSSA-loop is closing the carbon cycle, by completely oxidizing the carbon in the organic waste and non-edible parts of the plant into CO2 for higher plants and algae to fix again for food production. To further improve the overall degradation we are investigating the integration of a high temperature and pressure, sub- or near critical water conditions to improve the degradation of fibrous material with the addition of an oxidant (hydrogen peroxide, H2O2) under sub- or near critical conditions to further enhanced the oxidation to CO2. The conversion of the soluble organic compounds (mainly volatile fatty acids) into CO2 is being investigated with bio-anodic oxidation in a microbial electrolysis cell. In this way, the energy present in the organic compounds is recovered without excessive biological sludge production.

Closed-Loop Control of Humidification for Artifact Reduction in Capacitive ECG Measurements.

PubMed

Leicht, Lennart; Eilebrecht, Benjamin; Weyer, Soren; Leonhardt, Steffen; Teichmann, Daniel

2017-04-01

Recording biosignals without the need for direct skin contact offers new opportunities for ubiquitous health monitoring. Electrodes with capacitive coupling have been shown to be suitable for the monitoring of electrical potentials on the body surface, in particular ECG. However, due to triboelectric charge generation and motion artifacts, signal and thus diagnostic quality is inferior to galvanic coupling. Active closed-loop humidification of capacitive electrodes is proposed in this work as a new concept to improve signal quality. A capacitive ECG recording system integrated into a common car seat is presented. It can regulate the micro climate at the interface of electrode and patient by actively dispensing water vapour and monitoring humidity in a closed-loop approach. As a regenerative water reservoir, silica gel is used. The system was evaluated with respect to subjective and objective ECG signal quality. Active humidification was found to have a significant positive effect in case of previously poor quality. Also, it had no diminishing effect in case of already good signal quality.

Electric stimulation of the tuberomamillary nucleus affects epileptic activity and sleep-wake cycle in a genetic absence epilepsy model.

PubMed

Blik, Vitaliya

2015-01-01

Deep brain stimulation (DBS) is a promising approach for epilepsy treatment, but the optimal targets and parameters of stimulation are yet to be investigated. Tuberomamillary nucleus (TMN) is involved in EEG desynchronization-one of the proposed mechanisms for DBS action. We studied whether TMN stimulation could interfere with epileptic spike-wave discharges (SWDs) in WAG/Rij rats with inherited absence epilepsy and whether such stimulation would affect sleep-wake cycle. EEG and video registration were used to determine SWD occurrence and stages of sleep and wake during three-hours recording sessions. Stimulation (100Hz) was applied in two modes: closed-loop (with previously determined interruption threshold intensity) or open-loop mode (with 50% or 70% threshold intensity). Closed-loop stimulation successfully interrupted SWDs but elevated their number by 148 ± 54% compared to baseline. It was accompanied by increase in number of episodes but not total duration of both active and passive wakefulness. Open-loop stimulation with amplitude 50% threshold did not change measured parameters, though 70% threshold stimulation reduced SWDs number by 40 ± 9%, significantly raised the amount of active wakefulness and decreased the amount of both slow-wave and rapid eye movement sleep. These results suggest that the TMN is unfavorable as a target for DBS as its stimulation may cause alterations in sleep-wake cycle. A careful choosing of parameters and control of sleep-wake activity is necessary when applying DBS in epilepsy. Copyright © 2014 Elsevier B.V. All rights reserved.

Close-up view of Sodium Chloride crystals in a water bubble on Expedition Six.

NASA Image and Video Library

2003-03-13

ISS006-E-39211 (13 March 2003) --- A close up view of sodium chloride crystals in a water bubble within a 50-millimeter metal loop was photographed by an Expedition Six crewmember. The experiment took place in the Destiny laboratory on the International Space Station (ISS).

Close-up view of Sodium Chloride crystals in a water bubble on Expedition Six.

NASA Image and Video Library

2003-03-14

ISS006-E-39238 (14 March 2003) --- A close up view of sodium chloride crystals in a water bubble within a 50-millimeter metal loop was photographed by an Expedition Six crewmember. The experiment took place in the Destiny laboratory on the International Space Station (ISS).

Numerical analysis of radial inward flow turbine for CO2 based closed loop Brayton cycle

NASA Astrophysics Data System (ADS)

Kisan, Jadhav Amit; Govardhan, M.

2017-06-01

Last few decades have witnessed a phenomenal growth in the demand for power, which has driven the suppliers to find new sources of energy and increase the efficiency of power generation process. Power generation cycles are either steam based Rankine cycle or closed loop Brayton cycles providing an efficiency of 30 to 40%. An upcoming technology in this regard is the CO2 based Brayton cycle operating near the critical region which has applications in vast areas. Power generation of CO2 based Brayton cycle can vary from few kilowatts for waste heat recovery to hundreds of megawatts in sodium cooled fast reactors. A CO2 based Brayton cycle is being studied for power generation especially in mid-sized concentrated solar power plants by numerous research groups around the world. One of the main components of such a setting is its turbine. Simulating the flow conditions inside the turbine becomes very crucial in order to accurately predict the performance of the system. The flow inside radial inflow turbine is studied at various inlet temperatures and mass flow rates in order to predict the behavior of the turbine under various boundary conditions. The performance investigation of the turbine system is done on the basis of parameters such as total efficiency, pressure ratio, and power coefficient. Effect of different inlet stagnation temperature and exit mass flow rates on these parameters is also studied. Results obtained are encouraging for the use of CO2 as working fluid in Brayton cycle.

First Human Testing of the Orion Atmosphere Revitalization Technology

NASA Technical Reports Server (NTRS)

Lin, Amy; Sweterlitsch, Jeffrey

2009-01-01

An amine-based carbon dioxide (CO2) and water vapor sorbent in pressure-swing regenerable beds has been developed by Hamilton Sundstrand and baselined for the Orion Atmosphere Revitalization System (ARS). In two previous years at this conference, reports were presented on extensive Johnson Space Center (JSC) testing of the technology in a representative environment with simulated human metabolic loads. The next step in developmental testing at JSC was to replace the simulated humans with real humans; this testing was conducted in the spring of 2008. This first instance of human testing of a new Orion ARS technology included several cases in a sealed Orion-equivalent free volume and three cases using emergency breathing masks connected directly to the ARS loop. Significant test results presented in this paper include comparisons between the standard metabolic rates for CO2 and water vapor production published in Orion requirements documents and real-world rate ranges observed with human test subjects. Also included are qualitative assessments of process flow rate and closed-loop pressure-cycling tolerability while using the emergency masks. Recommendations for modifications to the Orion ARS design and operation, based on the test results, conclude the paper.

First Human Testing of the Orion Atmosphere Revitalization Technology

NASA Technical Reports Server (NTRS)

Lin, Amy; Sweterlitsch, Jeffrey

2008-01-01

An amine-based carbon dioxide (CO2) and water vapor sorbent in pressure-swing regenerable beds has been developed by Hamilton Sundstrand and baselined for the Orion Atmosphere Revitalization System (ARS). In two previous years at this conference, reports were presented on extensive Johnson Space Center (JSC) testing of the technology in a representative environment with simulated human metabolic loads. The next step in developmental testing at JSC was to replace the simulated humans with real humans; this testing was conducted in the spring of 2008. This first instance of human testing of a new Orion ARS technology included several cases in a sealed Orione-quivalent free volume and three cases using emergency breathing masks connected directly to the ARS loop. Significant test results presented in this paper include comparisons between the standard metabolic rates for CO2 and water vapor production published in Orion requirements documents and real-world rate ranges observed with human test subjects. Also included are qualitative assessments of process flow rate and closed-loop pressure-cycling tolerability while using the emergency masks. Recommendations for modifications to the Orion ARS design and operation, based on the test results, conclude the paper.

Ammonia Offgassing from SA9T

NASA Technical Reports Server (NTRS)

Monje, Oscar; Nolek, Sara D.; Wheeler, Raymond M.

2011-01-01

NH3 is a degradation product of SA9T, a solid-amine sorbent developed by Hamilton Sundstrand, that is continually emitted into the gas stream being conditioned by this sorbent. NH3 offgassing rates were measured using FTIR spectroscopy using a packed bed at similar contact times as offgassing tests conducted at Hamilton Sundstrand and at the Ames Research Center. The bed was challenged with moist air at several flow rates and humidities and NH3 concentration of the effluent was measured for several hours. The NH3 offgassing rates in open-loop testing were calculated from the steady state outlet NH3 concentration and flow rate. NH3 offgassing rates from SA9T were found to be influenced by the contact time with the adsorbent (flow rate) and by the humidity of the inlet gas stream, which are consistent with previous studies. Closed-loop vacuum-swing adsorption cycling rates verified that NH3 offgassing continues when a constant source of water vapor is present.

Bioethanol production from Scenedesmus obliquus sugars: the influence of photobioreactors and culture conditions on biomass production.

PubMed

Miranda, J R; Passarinho, P C; Gouveia, L

2012-10-01

A closed-loop vertical tubular photobioreactor (PBR), specially designed to operate under conditions of scarce flat land availability and irregular solar irradiance conditions, was used to study the potential of Scenedesmus obliquus biomass/sugar production. The results obtained were compared to those from an open-raceway pond and a closed-bubble column. The influence of the type of light source and the regime (natural vs artificial and continuous vs light/dark cycles) on the growth of the microalga and the extent of the sugar accumulation was studied in both PBRs. The best type of reactor studied was a closed-loop PBR illuminated with natural light/dark cycles. In all the cases, the relationship between the nitrate depletion and the sugar accumulation was observed. The microalga Scenedesmus was cultivated for 53 days in a raceway pond (4,500 L) and accumulated a maximum sugar content of 29 % g/g. It was pre-treated for carrying out ethanol fermentation assays, and the highest ethanol concentration obtained in the hydrolysate fermented by Kluyveromyces marxianus was 11.7 g/L.

Tool for the Integrated Dynamic Numerical Propulsion System Simulation (NPSS)/Turbine Engine Closed-Loop Transient Analysis (TTECTrA) User's Guide

NASA Technical Reports Server (NTRS)

Chin, Jeffrey C.; Csank, Jeffrey T.

2016-01-01

The Tool for Turbine Engine Closed-Loop Transient Analysis (TTECTrA ver2) is a control design tool thatenables preliminary estimation of transient performance for models without requiring a full nonlinear controller to bedesigned. The program is compatible with subsonic engine models implemented in the MATLAB/Simulink (TheMathworks, Inc.) environment and Numerical Propulsion System Simulation (NPSS) framework. At a specified flightcondition, TTECTrA will design a closed-loop controller meeting user-defined requirements in a semi or fully automatedfashion. Multiple specifications may be provided, in which case TTECTrA will design one controller for each, producing acollection of controllers in a single run. Each resulting controller contains a setpoint map, a schedule of setpointcontroller gains, and limiters; all contributing to transient characteristics. The goal of the program is to providesteady-state engine designers with more immediate feedback on the transient engine performance earlier in the design cycle.

Brayton cycle heat exchanger and duct assembly (HXDA, preliminary design and technology tests

NASA Technical Reports Server (NTRS)

Coombs, M. G.; Morse, C. J.; Graves, R. F.; Gibson, J. C.

1972-01-01

A preliminary design of the heat exchanger and duct assembly (HXDA) for a 60 kwe, closed loop, Brayton cycle space power system is presented. This system is weight optimized within the constraints imposed by the defined structural and operational requirements. Also presented are the results of several small scale tests, directed to obtaining specific design data and/or the resolution of a design approach for long life Brayton cycle heat exchanger systems.

Coral mucus fuels the sponge loop in warm- and cold-water coral reef ecosystems

PubMed Central

Rix, Laura; de Goeij, Jasper M.; Mueller, Christina E.; Struck, Ulrich; Middelburg, Jack J.; van Duyl, Fleur C.; Al-Horani, Fuad A.; Wild, Christian; Naumann, Malik S.; van Oevelen, Dick

2016-01-01

Shallow warm-water and deep-sea cold-water corals engineer the coral reef framework and fertilize reef communities by releasing coral mucus, a source of reef dissolved organic matter (DOM). By transforming DOM into particulate detritus, sponges play a key role in transferring the energy and nutrients in DOM to higher trophic levels on Caribbean reefs via the so-called sponge loop. Coral mucus may be a major DOM source for the sponge loop, but mucus uptake by sponges has not been demonstrated. Here we used laboratory stable isotope tracer experiments to show the transfer of coral mucus into the bulk tissue and phospholipid fatty acids of the warm-water sponge Mycale fistulifera and cold-water sponge Hymedesmia coriacea, demonstrating a direct trophic link between corals and reef sponges. Furthermore, 21–40% of the mucus carbon and 32–39% of the nitrogen assimilated by the sponges was subsequently released as detritus, confirming a sponge loop on Red Sea warm-water and north Atlantic cold-water coral reefs. The presence of a sponge loop in two vastly different reef environments suggests it is a ubiquitous feature of reef ecosystems contributing to the high biogeochemical cycling that may enable coral reefs to thrive in nutrient-limited (warm-water) and energy-limited (cold-water) environments. PMID:26740019

Coral mucus fuels the sponge loop in warm- and cold-water coral reef ecosystems.

PubMed

Rix, Laura; de Goeij, Jasper M; Mueller, Christina E; Struck, Ulrich; Middelburg, Jack J; van Duyl, Fleur C; Al-Horani, Fuad A; Wild, Christian; Naumann, Malik S; van Oevelen, Dick

2016-01-07

Shallow warm-water and deep-sea cold-water corals engineer the coral reef framework and fertilize reef communities by releasing coral mucus, a source of reef dissolved organic matter (DOM). By transforming DOM into particulate detritus, sponges play a key role in transferring the energy and nutrients in DOM to higher trophic levels on Caribbean reefs via the so-called sponge loop. Coral mucus may be a major DOM source for the sponge loop, but mucus uptake by sponges has not been demonstrated. Here we used laboratory stable isotope tracer experiments to show the transfer of coral mucus into the bulk tissue and phospholipid fatty acids of the warm-water sponge Mycale fistulifera and cold-water sponge Hymedesmia coriacea, demonstrating a direct trophic link between corals and reef sponges. Furthermore, 21-40% of the mucus carbon and 32-39% of the nitrogen assimilated by the sponges was subsequently released as detritus, confirming a sponge loop on Red Sea warm-water and north Atlantic cold-water coral reefs. The presence of a sponge loop in two vastly different reef environments suggests it is a ubiquitous feature of reef ecosystems contributing to the high biogeochemical cycling that may enable coral reefs to thrive in nutrient-limited (warm-water) and energy-limited (cold-water) environments.

Long-Duration Testing of a Temperature-Swing Adsorption Compressor for Carbon Dioxide for Closed-Loop Air Revitalization Systems

NASA Technical Reports Server (NTRS)

Rosen, Micha; Mulloth, Lila; Varghese, Mini

2005-01-01

This paper describes the results of long-duration testing of a temperature-swing adsorption compressor that has application in the International Space Station (ISS) and future spacecraft for closing the air revitalization loop. The air revitalization system of the ISS operates in an open loop mode and relies on the resupply of oxygen and other consumables from Earth for the life support of astronauts. A compressor is required for delivering the carbon dioxide from a removal assembly to a reduction unit to recover oxygen and thereby closing the air-loop. The TSAC is a solid-state compressor that has the capability to remove CO2 from a low-pressure source, and subsequently store, compress, and deliver at a higher pressure as required by a processor. The TSAC is an ideal interface device for CO2 removal and reduction units in the air revitalization loop of a spacecraft for oxygen recovery. The TSAC was developed and its operation was successfully verified in integration tests with the flight-like Carbon Dioxide Removal Assembly (CDRA) at Marshall Space Flight Center prior to the long-duration tests. Long-duration tests reveal the impacts of repeated thermal cycling on the compressor components and the adsorbent material.

Toward a hydro-political water cycle: virtual water,hydrology and international political economy

NASA Astrophysics Data System (ADS)

Greco, Francesca

2014-05-01

At the light of global food trade, no water cycle can be considered "closed" under a political point of view. While the hydrological cycle is a circular closed environment, if we open up our perspectives to social sciences, we will demonstrate how, thanks to virtual water, it is today possible to elaborate how much water 'enters or leave' any water body under the form crop-export, in terms of " water used for the production of agri-food products'. This new 'hydro-political cycle' will be discussed at the light of different theoretical perspectives: food trade theories, hydrology, international water law, socio-economic metabolism, material flow analysis.

A study on single lane-change manoeuvres for determining rearward amplification of multi-trailer articulated heavy vehicles with active trailer steering systems

NASA Astrophysics Data System (ADS)

Wang, Qiushi; He, Yuping

2016-01-01

The Society of Automotive Engineers issued a test procedure, SAE-J2179, to determine the rearward amplification (RA) of multi-trailer articulated heavy vehicles (MTAHVs). Built upon the procedure, the International Organization for Standardization released the test manoeuvres, ISO-14791, for evaluating directional performance of MTAHVs. For the RA measures, ISO-14791 recommends two single lane-change manoeuvres: (1) an open-loop procedure with a single sine-wave steering input; and (2) a closed-loop manoeuvre with a single sine-wave lateral acceleration input. For an articulated vehicle with active trailer steering (ATS), the RA measure in lateral acceleration under the open-loop manoeuvre was not in good agreement with that under the closed-loop manoeuvre. This observation motivates the research on the applicability of the two manoeuvres for the RA measures of MTAHVs with ATS. It is reported that transient response under the open-loop manoeuvre often leads to asymmetric curve of tractor lateral acceleration [Winkler CB, Fancher PS, Bareket Z, Bogard S, Johnson G, Karamihas S, Mink C. Heavy vehicle size and weight - test procedures for minimum safety performance standards. Final technical report, NHTSA, US DOT, contract DTNH22-87-D-17174, University of Michigan Transportation Research Institute, Report No. UMTRI-92-13; 1992]. To explore the effect of the transient response, a multiple cycle sine-wave steering input (MCSSI) manoeuvre is proposed. Simulation demonstrates that the steady-state RA measures of an MTAHV with and without ATS under the MCSSI manoeuvre are in excellent agreement with those under the closed-loop manoeuvre. It is indicated that between the two manoeuvres by ISO-14791, the closed-loop manoeuvre is more applicable for determining the RA measures of MTAHVs with ATS.

CLOSED-FIELD CORONAL HEATING DRIVEN BY WAVE TURBULENCE

DOE Office of Scientific and Technical Information (OSTI.GOV)

Downs, Cooper; Lionello, Roberto; Mikić, Zoran

To simulate the energy balance of coronal plasmas on macroscopic scales, we often require the specification of the coronal heating mechanism in some functional form. To go beyond empirical formulations and to build a more physically motivated heating function, we investigate the wave-turbulence-driven (WTD) phenomenology for the heating of closed coronal loops. Our implementation is designed to capture the large-scale propagation, reflection, and dissipation of wave turbulence along a loop. The parameter space of this model is explored by solving the coupled WTD and hydrodynamic evolution in 1D for an idealized loop. The relevance to a range of solar conditionsmore » is also established by computing solutions for over one hundred loops extracted from a realistic 3D coronal field. Due to the implicit dependence of the WTD heating model on loop geometry and plasma properties along the loop and at the footpoints, we find that this model can significantly reduce the number of free parameters when compared to traditional empirical heating models, and still robustly describe a broad range of quiet-Sun and active region conditions. The importance of the self-reflection term in producing relatively short heating scale heights and thermal nonequilibrium cycles is also discussed.« less

Closed-field Coronal Heating Driven by Wave Turbulence

NASA Astrophysics Data System (ADS)

Downs, Cooper; Lionello, Roberto; Mikić, Zoran; Linker, Jon A.; Velli, Marco

2016-12-01

To simulate the energy balance of coronal plasmas on macroscopic scales, we often require the specification of the coronal heating mechanism in some functional form. To go beyond empirical formulations and to build a more physically motivated heating function, we investigate the wave-turbulence-driven (WTD) phenomenology for the heating of closed coronal loops. Our implementation is designed to capture the large-scale propagation, reflection, and dissipation of wave turbulence along a loop. The parameter space of this model is explored by solving the coupled WTD and hydrodynamic evolution in 1D for an idealized loop. The relevance to a range of solar conditions is also established by computing solutions for over one hundred loops extracted from a realistic 3D coronal field. Due to the implicit dependence of the WTD heating model on loop geometry and plasma properties along the loop and at the footpoints, we find that this model can significantly reduce the number of free parameters when compared to traditional empirical heating models, and still robustly describe a broad range of quiet-Sun and active region conditions. The importance of the self-reflection term in producing relatively short heating scale heights and thermal nonequilibrium cycles is also discussed.

Closing the loop of the soil water retention curve

USGS Publications Warehouse

Lu, Ning; Alsherif, N; Wayllace, Alexandra; Godt, Jonathan W.

2015-01-01

The authors, to their knowledge for the first time, produced two complete principal soil water retention curves (SWRCs) under both positive and negative matric suction regimes. An innovative testing technique combining the transient water release and imbibition method (TRIM) and constant flow method (CFM) was used to identify the principal paths of SWRC in the positive pore-water pressure regime under unsaturated conditions. A negative matric suction of 9.8 kPa is needed to reach full saturation or close the loop of the SWRC for a silty soil. This work pushes the understanding of the interaction of soil and water into new territory by quantifying the boundaries of the SWRC over the entire suction domain, including both wetting and drying conditions that are relevant to field conditions such as slope wetting under heavy rainfall or rapid groundwater table rise in earthen dams or levees.

Continental Growth and Mantle Hydration as Earth System Feedback Cycles and possible Effects of the Biosphere

NASA Astrophysics Data System (ADS)

Höning, D.; Spohn, T.

2016-12-01

The evolution of Earth is charcterized by intertwined feedback cycles. We focus on two feedback cycles that include the mantle water budget and the continental crust and study possible effects of the Earth's biosphere. The first feedback loop includes cycling of water into the mantle at subduction zones and outgassing at volcanic chains and mid-ocean ridges. Water will reduce the viscosity of mantle rock, and therefore the speed of mantle convection and plate subduction will increase with the mantle water concentration, eventually enhancing the rates of mantle water regassing and outgassing. A second feedback loop includes the production and erosion of continental crust. Continents grow by volcanism above subduction zones, whose total length is determined by the total area of the continents. Furthermore, the erosion rate of the continents is proportional to the total surface area of continental crust. The rate of sediment subduction affects the rate of transport of water to the mantle and the production rate of new continental crust. We present a model that includes both cycles and show how the system develops stable and unstable fixed points in a plane defined by mantle water concentration and surface are of continents. The stable points represent either an Earth mostly covered by continents and a wet mantle or an Earth mostly covered by oceans with a dry mantle. The presently observed Earth is inbetween these extreme states but the state is intrinsically unstable. We couple the feedback model to a parameterized thermal evolution model. We show how Earth evolved towards its present unstable state. We argue that other feedback cycles such as the carbonate silicate cycle may act to stabilize the present state, however. By enhancing continental weathering and erosion, and eventually the sediment transport into subduction zones, the biosphere impacts both feedback cycles and might play a crucial role in regulating Earth's system and keep continental crust coverage and mantle water budget at its present day state.

Closed loop statistical performance analysis of N-K knock controllers

NASA Astrophysics Data System (ADS)

Peyton Jones, James C.; Shayestehmanesh, Saeed; Frey, Jesse

2017-09-01

The closed loop performance of engine knock controllers cannot be rigorously assessed from single experiments or simulations because knock behaves as a random process and therefore the response belongs to a random distribution also. In this work a new method is proposed for computing the distributions and expected values of the closed loop response, both in steady state and in response to disturbances. The method takes as its input the control law, and the knock propensity characteristic of the engine which is mapped from open loop steady state tests. The method is applicable to the 'n-k' class of knock controllers in which the control action is a function only of the number of cycles n since the last control move, and the number k of knock events that have occurred in this time. A Cumulative Summation (CumSum) based controller falls within this category, and the method is used to investigate the performance of the controller in a deeper and more rigorous way than has previously been possible. The results are validated using onerous Monte Carlo simulations, which confirm both the validity of the method and its high computational efficiency.

Volitional control of anticipatory ocular pursuit responses under stabilised image conditions in humans.

PubMed

Barnes, G; Goodbody, S; Collins, S

1995-01-01

Ocular pursuit responses have been examined in humans in three experiments in which the pursuit target image has been fully or partially stabilised on the fovea by feeding a recorded eye movement signal back to drive the target motion. The objective was to establish whether subjects could volitionally control smooth eye movement to reproduce trajectories of target motion in the absence of a concurrent target motion stimulus. In experiment 1 subjects were presented with a target moving with a triangular waveform in the horizontal axis with a frequency of 0.325 Hz and velocities of +/- 10-50 degrees/s. The target was illuminated twice per cycle for pulse durations (PD) of 160-640 ms as it passed through the centre position; otherwise subjects were in darkness. Subjects initially tracked the target motion in a conventional closed-loop mode for four cycles. Prior to the next target presentation the target image was stabilised on the fovea, so that any target motion generated resulted solely from volitional eye movement. Subjects continued to make anticipatory smooth eye movements both to the left and the right with a velocity trajectory similar to that observed in the closed-loop phase. Peak velocity in the stabilised-image mode was highly correlated with that in the prior closed-loop phase, but was slightly less (84% on average). In experiment 2 subjects were presented with a continuously illuminated target that was oscillated sinusoidally at frequencies of 0.2-1.34 Hz and amplitudes of +/- 5-20 degrees. After four cycles of closed-loop stimulation the image was stabilised on the fovea at the time of peak target displacement. Subjects continued to generate an oscillatory smooth eye velocity pattern that mimicked the sinusoidal motion of the previous closed-loop phase for at least three further cycles. The peak eye velocity generated ranged from 57-95% of that in the closed-loop phase at frequencies up to 0.8 Hz but decreased significantly at 1.34 Hz. In experiment 3 subjects were presented with a stabilised display throughout and generated smooth eye movements with peak velocity up to 84 degrees/s in the complete absence of any prior external target motion stimulus, by transferring their attention alternately to left and right of the centre of the display. Eye velocity was found to be dependent on the eccentricity of the centre of attention and the frequency of alternation. When the target was partially stabilised on the retina by feeding back only a proportion (Kf = 0.6-0.9) of the eye movement signal to drive the target, subjects were still able to generate smooth movements at will, even though the display did not move as far or as fast as the eye. Peak eye velocity decreased as Kf decreased, suggesting that there was a continuous competitive interaction between the volitional drive and the visual feedback provided by the relative motion of the display with respect to the retina. These results support the evidence for two separate mechanisms of smooth eye movement control in ocular pursuit: reflex control from retinal velocity error feedback and volitional control from an internal source. Arguments are presented to indicate how smooth pursuit may be controlled by matching a voluntarily initiated estimate of the required smooth movement, normally derived from storage of past re-afferent information, against current visual feedback information. Such a mechanism allows preemptive smooth eye movements to be made that can overcome the inherent delays in the visual feedback pathway.

Modeling and Simulation of a Parametrically Resonant Micromirror With Duty-Cycled Excitation.

PubMed

Shahid, Wajiha; Qiu, Zhen; Duan, Xiyu; Li, Haijun; Wang, Thomas D; Oldham, Kenn R

2014-12-01

High frequency large scanning angle electrostatically actuated microelectromechanical systems (MEMS) mirrors are used in a variety of applications involving fast optical scanning. A 1-D parametrically resonant torsional micromirror for use in biomedical imaging is analyzed here with respect to operation by duty-cycled square waves. Duty-cycled square wave excitation can have significant advantages for practical mirror regulation and/or control. The mirror's nonlinear dynamics under such excitation is analyzed in a Hill's equation form. This form is used to predict stability regions (the voltage-frequency relationship) of parametric resonance behavior over large scanning angles using iterative approximations for nonlinear capacitance behavior of the mirror. Numerical simulations are also performed to obtain the mirror's frequency response over several voltages for various duty cycles. Frequency sweeps, stability results, and duty cycle trends from both analytical and simulation methods are compared with experimental results. Both analytical models and simulations show good agreement with experimental results over the range of duty cycled excitations tested. This paper discusses the implications of changing amplitude and phase with duty cycle for robust open-loop operation and future closed-loop operating strategies.

Clearing the Air: New Approaches to Life Support in Outer Space

NASA Technical Reports Server (NTRS)

Knox, J.; Howard, D.

2008-01-01

This article reports on research into atmospheric revitalization systems for long-term space travel and the use ofCOMSOL Multiphysics to understand how structured sorbents can be used to improve the performance of adsorption processes via thermal management. We are developing the next generation of atmosphere revitalization systems, which will reach for new levels of resource conservation via a high percentage of loop closure. For example, a high percentage of carbon dioxide, exhaled by crew, can be converted via reaction to drinking water, closing the loop from human metabolic waste to supply. Adsorption processes play a lead role in these new/closed loop systems.

Diversity of microbial communities correlated to physiochemical parameters in a digestion basin of a zero-discharge mariculture system.

PubMed

Cytryn, Eddie; Gelfand, Ilya; Barak, Yoram; van Rijn, Jaap; Minz, Dror

2003-01-01

Bacterial community structure and physiochemical parameters were examined in a sedimentation basin of a zero-discharge mariculture system. The system consisted of an intensively stocked fish basin from which water was recirculated through two separate treatment loops. Surface water from the basin was pumped over a trickling filter in one loop while bottom-water was recirculated through a sedimentation basin followed by a fluidized bed reactor in the other. Ammonia oxidation to nitrate in the trickling filter and organic matter digestion together with nitrate reduction in the sedimentation basin and fluidized bed reactor, allowed zero-discharge operation of the system. Relatively high concentrations of oxygen, nitrate, sulphate and organic matter detected simultaneously in the digestion basin suggested the potential for a wide range of microbially-mediated transformation processes. In this study, physiochemical parameters were correlated to bacterial diversity and distribution in horizontal and vertical profiles within this basin in an effort to obtain a basic understanding of the chemical and microbial processes in this system. Chemical activity and microbial diversity, the latter measured by denaturing gradient gel electrophoresis (DGGE) analysis of polymerase chain reaction (PCR) amplified 16S rDNA fragments, were higher in the sludge layer than in the overlying aqueous layer of the basin. Chemical parameters in sludge samples close to the basin inlet suggested enhanced microbial activity relative to other sampling areas with evidence of both nitrate and sulphate reduction. Four of the nine DGGE bands identified in this zone were affiliated with the Bacteroidetes phylum. Detected sequences closely related to sequences of organisms involved in the sulphur cycle included Desulfovibrio, Dethiosulfovibrio and apparent sulphur oxidizers from the gamma-proteobacteria. In addition, a number of sequences from the beta and alpha-proteobacteria were identified.

Performance of the Extravehicular Mobility Unit (EMU) Airlock Coolant Loop Remediation (A/L CLR) Hardware - Final

NASA Technical Reports Server (NTRS)

Steele, John W.; Rector, Tony; Gazda, Daniel; Lewis, John

2011-01-01

An EMU water processing kit (Airlock Coolant Loop Recovery -- A/L CLR) was developed as a corrective action to Extravehicular Mobility Unit (EMU) coolant flow disruptions experienced on the International Space Station (ISS) in May of 2004 and thereafter. A conservative duty cycle and set of use parameters for A/L CLR use and component life were initially developed and implemented based on prior analysis results and analytical modeling. Several initiatives were undertaken to optimize the duty cycle and use parameters of the hardware. Examination of post-flight samples and EMU Coolant Loop hardware provided invaluable information on the performance of the A/L CLR and has allowed for an optimization of the process. The intent of this paper is to detail the evolution of the A/L CLR hardware, efforts to optimize the duty cycle and use parameters, and the final recommendations for implementation in the post-Shuttle retirement era.

Gas engine heat pump cycle analysis. Volume 1: Model description and generic analysis

NASA Astrophysics Data System (ADS)

Fischer, R. D.

1986-10-01

The task has prepared performance and cost information to assist in evaluating the selection of high voltage alternating current components, values for component design variables, and system configurations and operating strategy. A steady-state computer model for performance simulation of engine-driven and electrically driven heat pumps was prepared and effectively used for parametric and seasonal performance analyses. Parametric analysis showed the effect of variables associated with design of recuperators, brine coils, domestic hot water heat exchanger, compressor size, engine efficiency, insulation on exhaust and brine piping. Seasonal performance data were prepared for residential and commercial units in six cities with system configurations closely related to existing or contemplated hardware of the five GRI engine contractors. Similar data were prepared for an advanced variable-speed electric unit for comparison purposes. The effect of domestic hot water production on operating costs was determined. Four fan-operating strategies and two brine loop configurations were explored.

Sabatier Reactor System Integration with Microwave Plasma Methane Pyrolysis Post-Processor for Closed-Loop Hydrogen Recovery

NASA Technical Reports Server (NTRS)

Abney, Morgan B.; Miller, Lee A.; Williams, Tom

2010-01-01

The Carbon Dioxide Reduction Assembly (CRA) designed and developed for the International Space Station (ISS) represents the state-of-the-art in carbon dioxide reduction (CDRe) technology. The CRA produces water and methane by reducing carbon dioxide with hydrogen via the Sabatier reaction. The water is recycled to the Oxygen Generation Assembly (OGA) and the methane is vented overboard resulting in a net loss of hydrogen. The proximity to earth and the relative ease of logistics resupply from earth allow for a semi-closed system on ISS. However, long-term manned space flight beyond low earth orbit (LEO) dictates a more thoroughly closed-loop system involving significantly higher recovery of hydrogen, and subsequent recovery of oxygen, to minimize costs associated with logistics resupply beyond LEO. The open-loop ISS system for CDRe can be made closed-loop for follow-on missions by further processing methane to recover hydrogen. For this purpose, a process technology has been developed that employs a microwave-generated plasma to reduce methane to hydrogen and acetylene resulting in 75% theoretical recovery of hydrogen. In 2009, a 1-man equivalent Plasma Pyrolysis Assembly (PPA) was delivered to the National Aeronautics and Space Administration (NASA) for technical evaluation. The PPA has been integrated with a Sabatier Development Unit (SDU). The integrated process configuration incorporates a sorbent bed to eliminate residual carbon dioxide and water vapor in the Sabatier methane product stream before it enters the PPA. This paper provides detailed information on the stand-alone and integrated performance of both the PPA and SDU. Additionally, the integrated test stand design and anticipated future work are discussed.

Comparison of Five System Identification Algorithms for Rotorcraft Higher Harmonic Control

NASA Technical Reports Server (NTRS)

Jacklin, Stephen A.

1998-01-01

This report presents an analysis and performance comparison of five system identification algorithms. The methods are presented in the context of identifying a frequency-domain transfer matrix for the higher harmonic control (HHC) of helicopter vibration. The five system identification algorithms include three previously proposed methods: (1) the weighted-least- squares-error approach (in moving-block format), (2) the Kalman filter method, and (3) the least-mean-squares (LMS) filter method. In addition there are two new ones: (4) a generalized Kalman filter method and (5) a generalized LMS filter method. The generalized Kalman filter method and the generalized LMS filter method were derived as extensions of the classic methods to permit identification by using more than one measurement per identification cycle. Simulation results are presented for conditions ranging from the ideal case of a stationary transfer matrix and no measurement noise to the more complex cases involving both measurement noise and transfer-matrix variation. Both open-loop identification and closed- loop identification were simulated. Closed-loop mode identification was more challenging than open-loop identification because of the decreasing signal-to-noise ratio as the vibration became reduced. The closed-loop simulation considered both local-model identification, with measured vibration feedback and global-model identification with feedback of the identified uncontrolled vibration. The algorithms were evaluated in terms of their accuracy, stability, convergence properties, computation speeds, and relative ease of implementation.

Experimentally Determined Overall Heat Transfer Coefficients for Spacesuit Liquid Cooled Garments

NASA Technical Reports Server (NTRS)

Bue, Grant; Rhodes, Richard; Anchondo, Ian; Westheimer, David; Campbell, Colin; Vogel, Matt; Vonaue, Walt; Conger, Bruce; Stein, James

2015-01-01

A Human-In-The-Loop (HITL) Portable Life Support System 2.0 (PLSS 2.0) test has been conducted at NASA Johnson Space Center in the PLSS Development Laboratory from October 27, 2014 to December 19, 2014. These closed-loop tests of the PLSS 2.0 system integrated with human subjects in the Mark III Suit at 3.7 psi to 4.3 psi above ambient pressure performing treadmill exercise at various metabolic rates from standing rest to 3000 BTU/hr (880 W). The bulk of the PLSS 2.0 was at ambient pressure but effluent water vapor from the Spacesuit Water Membrane Evaporator (SWME) and the Auxiliary Membrane Evaporator (Mini-ME), and effluent carbon dioxide from the Rapid Cycle Amine (RCA) were ported to vacuum to test performance of these components in flight-like conditions. One of the objectives of this test was to determine the overall heat transfer coefficient (UA) of the Liquid Cooling Garment (LCG). The UA, an important factor for modeling the heat rejection of an LCG, was determined in a variety of conditions by varying inlet water temperature, flow rate, and metabolic rate. Three LCG configurations were tested: the Extravehicular Mobility Unit (EMU) LCG, the Oceaneering Space Systems (OSS) LCG, and the OSS auxiliary LCG. Other factors influencing accurate UA determination, such as overall heat balance, LCG fit, and the skin temperature measurement, will also be discussed.

Experimentally Determined Heat Transfer Coefficients for Spacesuit Liquid Cooled Garments

NASA Technical Reports Server (NTRS)

Bue, Grant; Watts, Carly; Rhodes, Richard; Anchondo, Ian; Westheimer, David; Campbell, Colin; Vonau, Walt; Vogel, Matt; Conger, Bruce

2015-01-01

A Human-In-The-Loop (HITL) Portable Life Support System 2.0 (PLSS 2.0) test has been conducted at NASA Johnson Space Center in the PLSS Development Laboratory from October 27, 2014 to December 19, 2014. These closed-loop tests of the PLSS 2.0 system integrated with human subjects in the Mark III Suit at 3.7 psi to 4.3 psi above ambient pressure performing treadmill exercise at various metabolic rates from standing rest to 3000 BTU/hr (880 W). The bulk of the PLSS 2.0 was at ambient pressure but effluent water vapor from the Spacesuit Water Membrane Evaporator (SWME) and the Auxiliary Membrane Evaporator (Mini-ME), and effluent carbon dioxide from the Rapid Cycle Amine (RCA) were ported to vacuum to test performance of these components in flight-like conditions. One of the objectives of this test was to determine the heat transfer coefficient (UA) of the Liquid Cooling Garment (LCG). The UA, an important factor for modeling the heat rejection of an LCG, was determined in a variety of conditions by varying inlet water temperature, flowrate, and metabolic rate. Three LCG configurations were tested: the Extravehicular Mobility Unit (EMU) LCG, the Oceaneering Space Systems (OSS) LCG, and the OSS auxiliary LCG. Other factors influencing accurate UA determination, such as overall heat balance, LCG fit, and the skin temperature measurement, will also be discussed.

View of salt crystals inserted within a 50mm metal loop in the U.S. Laboratory

NASA Image and Video Library

2003-03-15

ISS006-E-39339 (15 March 2003) --- A close up view of sodium chloride crystals in a water bubble within a 50-millimeter metal loop was photographed by an Expedition Six crewmember. The experiment took place in the Destiny laboratory on the International Space Station (ISS).

Heat-transfer analysis of double-pipe heat exchangers for indirect-cycle SCW NPP

NASA Astrophysics Data System (ADS)

Thind, Harwinder

SuperCritical-Water-cooled Reactors (SCWRs) are being developed as one of the Generation-IV nuclear-reactor concepts. SuperCritical Water (SCW) Nuclear Power Plants (NPPs) are expected to have much higher operating parameters compared to current NPPs, i.e., pressure of about 25 MPa and outlet temperature up to 625 °C. This study presents the heat transfer analysis of an intermediate Heat exchanger (HX) design for indirect-cycle concepts of Pressure-Tube (PT) and Pressure-Vessel (PV) SCWRs. Thermodynamic configurations with an intermediate HX gives a possibility to have a single-reheat option for PT and PV SCWRs without introducing steam-reheat channels into a reactor. Similar to the current CANDU and Pressurized Water Reactor (PWR) NPPs, steam generators separate the primary loop from the secondary loop. In this way, the primary loop can be completely enclosed in a reactor containment building. This study analyzes the heat transfer from a SCW primary (reactor) loop to a SCW and Super-Heated Steam (SHS) secondary (turbine) loop using a double-pipe intermediate HX. The numerical model is developed with MATLAB and NIST REFPROP software. Water from the primary loop flows through the inner pipe, and water from the secondary loop flows through the annulus in the counter direction of the double-pipe HX. The analysis on the double-pipe HX shows temperature and profiles of thermophysical properties along the heated length of the HX. It was found that the pseudocritical region has a significant effect on the temperature profiles and heat-transfer area of the HX. An analysis shows the effect of variation in pressure, temperature, mass flow rate, and pipe size on the pseudocritical region and the heat-transfer area of the HX. The results from the numerical model can be used to optimize the heat-transfer area of the HX. The higher pressure difference on the hot side and higher temperature difference between the hot and cold sides reduces the pseudocritical-region length, thus decreases the heat-transfer surface area of the HX.

Simple equations to simulate closed-loop recycling liquid-liquid chromatography: Ideal and non-ideal recycling models.

PubMed

Kostanyan, Artak E

2015-12-04

The ideal (the column outlet is directly connected to the column inlet) and non-ideal (includes the effects of extra-column dispersion) recycling equilibrium-cell models are used to simulate closed-loop recycling counter-current chromatography (CLR CCC). Simple chromatogram equations for the individual cycles and equations describing the transport and broadening of single peaks and complex chromatograms inside the recycling closed-loop column for ideal and non-ideal recycling models are presented. The extra-column dispersion is included in the theoretical analysis, by replacing the recycling system (connecting lines, pump and valving) by a cascade of Nec perfectly mixed cells. To evaluate extra-column contribution to band broadening, two limiting regimes of recycling are analyzed: plug-flow, Nec→∞, and maximum extra-column dispersion, Nec=1. Comparative analysis of ideal and non-ideal models has shown that when the volume of the recycling system is less than one percent of the column volume, the influence of the extra-column processes on the CLR CCC separation may be neglected. Copyright © 2015 Elsevier B.V. All rights reserved.

Accurate predictor-corrector skip entry guidance for low lift-to-drag ratio spacecraft

NASA Astrophysics Data System (ADS)

Enmi, Y.; Qian, W.; He, K.; Di, D.

2018-06-01

This paper develops numerical predictor-corrector skip en try guidance for vehicles with low lift-to-drag L/D ratio during the skip entry phase of a Moon return mission. The guidance method is composed of two parts: trajectory planning before entry and closed-loop gu idance during skip entry. The result of trajectory planning before entry is able to present an initial value for predictor-corrector algorithm in closed-loop guidance for fast convergence. The magnitude of bank angle, which is parameterized as a linear function of the range-to-go, is modulated to satisfy the downrange requirements. The sign of the bank ang le is determined by the bank-reversal logic. The predictor-corrector algorithm repeatedly applied onboard in each guidance cycle to realize closed-loop guidance in the skip entry phase. The effectivity of the proposed guidance is validated by simulations in nominal conditions, including skip entry, loft entry, and direct entry, as well as simulations in dispersion conditions considering the combination disturbance of the entry interface, the aerodynamic coefficients, the air density, and the mass of the vehicle.

Emissions performance of abatement technologies over the proposed EEC extra-urban driving cycle

DOE Office of Scientific and Technical Information (OSTI.GOV)

VanBeckhoven, L.C.; Rijkeboer, R.C.

1989-01-01

The definition of what is likely to be the new EEC extra-urban cycle has made it possible to determine the emission characteristics of cars fitted with different emissions control equipment. Central to the evaluation program were three versions of experimental lean and dilute burn engines compared with engine modifications and open and closed loop three-way catalyst systems. This paper describes the evaluation program and evaluates its results.

Visualizing Active-Site Dynamics in Single Crystals of HePTP: Opening of the WPD Loop Involves Coordinated Movement of the E Loop

DOE Office of Scientific and Technical Information (OSTI.GOV)

D Critton; L Tautz; R Page

2011-12-31

Phosphotyrosine hydrolysis by protein tyrosine phosphatases (PTPs) involves substrate binding by the PTP loop and closure over the active site by the WPD loop. The E loop, located immediately adjacent to the PTP and WPD loops, is conserved among human PTPs in both sequence and structure, yet the role of this loop in substrate binding and catalysis is comparatively unexplored. Hematopoietic PTP (HePTP) is a member of the kinase interaction motif (KIM) PTP family. Compared to other PTPs, KIM-PTPs have E loops that are unique in both sequence and structure. In order to understand the role of the E loopmore » in the transition between the closed state and the open state of HePTP, we identified a novel crystal form of HePTP that allowed the closed-state-to-open-state transition to be observed within a single crystal form. These structures, which include the first structure of the HePTP open state, show that the WPD loop adopts an 'atypically open' conformation and, importantly, that ligands can be exchanged at the active site, which is critical for HePTP inhibitor development. These structures also show that tetrahedral oxyanions bind at a novel secondary site and function to coordinate the PTP, WPD, and E loops. Finally, using both structural and kinetic data, we reveal a novel role for E-loop residue Lys182 in enhancing HePTP catalytic activity through its interaction with Asp236 of the WPD loop, providing the first evidence for the coordinated dynamics of the WPD and E loops in the catalytic cycle, which, as we show, is relevant to multiple PTP families.« less

System identification from closed-loop data with known output feedback dynamics

NASA Technical Reports Server (NTRS)

Phan, Minh; Juang, Jer-Nan; Horta, Lucas G.; Longman, Richard W.

1992-01-01

This paper presents a procedure to identify the open loop systems when it is operating under closed loop conditions. First, closed loop excitation data are used to compute the system open loop and closed loop Markov parameters. The Markov parameters, which are the pulse response samples, are then used to compute a state space representation of the open loop system. Two closed loop configurations are considered in this paper. The closed loop system can have either a linear output feedback controller or a dynamic output feedback controller. Numerical examples are provided to illustrate the proposed closed loop identification method.

Closed loop steam cooled airfoil

DOEpatents

Widrig, Scott M.; Rudolph, Ronald J.; Wagner, Gregg P.

2006-04-18

An airfoil, a method of manufacturing an airfoil, and a system for cooling an airfoil is provided. The cooling system can be used with an airfoil located in the first stages of a combustion turbine within a combined cycle power generation plant and involves flowing closed loop steam through a pin array set within an airfoil. The airfoil can comprise a cavity having a cooling chamber bounded by an interior wall and an exterior wall so that steam can enter the cavity, pass through the pin array, and then return to the cavity to thereby cool the airfoil. The method of manufacturing an airfoil can include a type of lost wax investment casting process in which a pin array is cast into an airfoil to form a cooling chamber.

Resilience of microbial communities in a simulated drinking water distribution system subjected to disturbances: role of conditionally rare taxa and potential implications for antibiotic-resistant bacteria

EPA Science Inventory

Many US water utilities using chloramine as their secondary disinfectant have experienced nitrification episodes that detrimentally impact water quality in their distribution systems. A semi-closed pipe-loop chloraminated drinking water distribution system (DWDS) simulator was u...

A coupled human-water system from a systems dynamics perspective

NASA Astrophysics Data System (ADS)

Kuil, Linda; Blöschl, Günter; Carr, Gemma

2013-04-01

Traditionally, models used in hydrological studies have frequently assumed stationarity. Moreover, human-induced water resources management activities are often included as external forcings in water cycle dynamics. However, considering humans' current impact on the water cycle in terms of a growing population, river basins increasingly being managed and a climate considerably changing, it has recently been questioned whether this is still correct. Furthermore, research directed at the evolution of water resources and society has shown that the components constituting the human-water system are changing interdependently. Goal of this study is therefore to approach water cycle dynamics from an integrated perspective in which humans are considered as endogenous forces to the system. The method used to model a coupled, urban human-water system is system dynamics. In system dynamics, particular emphasis is placed on feedback loops resulting in dynamic behavior. Time delays and non-linearity can relatively easily be included, making the method appropriate for studying complex systems that change over time. The approach of this study is as follows. First, a conceptual model is created incorporating the key components of the urban human-water system. Subsequently, only those components are selected that are both relevant and show causal loop behavior. Lastly, the causal narratives are translated into mathematical relationships. The outcome will be a simple model that shows only those characteristics with which we are able to explore the two-way coupling between the societal behavior and the water system we depend on.

Modeling and Simulation of a Parametrically Resonant Micromirror With Duty-Cycled Excitation

PubMed Central

Shahid, Wajiha; Qiu, Zhen; Duan, Xiyu; Li, Haijun; Wang, Thomas D.; Oldham, Kenn R.

2014-01-01

High frequency large scanning angle electrostatically actuated microelectromechanical systems (MEMS) mirrors are used in a variety of applications involving fast optical scanning. A 1-D parametrically resonant torsional micromirror for use in biomedical imaging is analyzed here with respect to operation by duty-cycled square waves. Duty-cycled square wave excitation can have significant advantages for practical mirror regulation and/or control. The mirror’s nonlinear dynamics under such excitation is analyzed in a Hill’s equation form. This form is used to predict stability regions (the voltage-frequency relationship) of parametric resonance behavior over large scanning angles using iterative approximations for nonlinear capacitance behavior of the mirror. Numerical simulations are also performed to obtain the mirror’s frequency response over several voltages for various duty cycles. Frequency sweeps, stability results, and duty cycle trends from both analytical and simulation methods are compared with experimental results. Both analytical models and simulations show good agreement with experimental results over the range of duty cycled excitations tested. This paper discusses the implications of changing amplitude and phase with duty cycle for robust open-loop operation and future closed-loop operating strategies. PMID:25506188

Space Life Support Engineering Program

NASA Technical Reports Server (NTRS)

Seagrave, Richard C.

1993-01-01

This report covers the second year of research relating to the development of closed-loop long-term life support systems. Emphasis was directed toward concentrating on the development of dynamic simulation techniques and software and on performing a thermodynamic systems analysis in an effort to begin optimizing the system needed for water purification. Four appendices are attached. The first covers the ASPEN modeling of the closed loop Environmental Control Life Support System (ECLSS) and its thermodynamic analysis. The second is a report on the dynamic model development for water regulation in humans. The third regards the development of an interactive computer-based model for determining exercise limitations. The fourth attachment is an estimate of the second law thermodynamic efficiency of the various units comprising an ECLSS.

Conformational motions regulate phosphoryl transfer in related protein tyrosine phosphatases

PubMed Central

Whittier, Sean K.; Hengge, Alvan C.; Loria, J. Patrick

2014-01-01

Many studies have implicated a role for conformational motions during the catalytic cycle, acting to optimize the binding pocket or facilitate product release, but a more intimate role in the chemical reaction has not been described. We address this by monitoring active-site loop motion in two protein tyrosine phosphatases (PTPs) using NMR spectroscopy. The PTPs, YopH and PTP1B, have very different catalytic rates, however we find in both that the active-site loop closes to its catalytically competent position at rates that mirror the phosphotyrosine cleavage kinetics. This loop contains the catalytic acid, suggesting that loop closure occurs concomitantly with the protonation of the leaving group tyrosine and explains the different kinetics of two otherwise chemically and mechanistically indistinguishable enzymes. PMID:23970698

Biocides: Capturing bugs and bigger markets

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hairston, D.W.

1995-10-01

Deep in the dark interior of cooling water towers, intake streams and purifiers, there is a jungle. Hundreds of thousands of microorganisms dwell in algae and biofilm, breeding mutant and increasingly resistant strains of bacteria. For biocide manufacturers, the imperative is to find better ways to control the proliferation of the microscopic bugs. Some of the most robust demand for biocides is in the cooling water market, particularly as industrial water treatment continues to switch from gaseous chlorine to bromine compounds. The trend toward closed-loop and faster cycles for process water treatment will require more biological control. Biocides are expectedmore » to benefit from that trend, but in pulp and paper operations, chlorine dioxide may reap the biggest gains. Also making inroads is an electrolytic system that uses ClO{sub 2} to control microorganisms in cooling towers. Despite growing demand for safe and more-effective biocides in Europe and the US, new product development is stymied by the rigorous and costly process of getting regulatory approval. In the US, EPA registration can cost $5--10 million and take 5 to 10 years.« less

Thermal boundary layer due to sudden heating of fluid

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kurkal, K.R.; Munukutla, S.

This paper proposes to solve computationally the heat-transfer problems (introduced by Munukutla and Venkataraman, 1988) related to a closed-cycle pulsed high-power laser flow loop. The continuity and the momentum equations as well as the unsteady energy equation are solved using the Keller-Box method. The solutions were compared with the steady-state solutions at large times, and the comparison was found to be excellent. Empirical formulas are proposed for calculating the time-dependent boundary-layer thickness and mass-heat transfer, that can be used by laser flow loop designers. 6 refs.

Thermal boundary layer due to sudden heating of fluid

NASA Astrophysics Data System (ADS)

Kurkal, K. R.; Munukutla, S.

1989-10-01

This paper proposes to solve computationally the heat-transfer problems (introduced by Munukutla and Venkataraman, 1988) related to a closed-cycle pulsed high-power laser flow loop. The continuity and the momentum equations as well as the unsteady energy equation are solved using the Keller-Box method. The solutions were compared with the steady-state solutions at large times, and the comparison was found to be excellent. Empirical formulas are proposed for calculating the time-dependent boundary-layer thickness and mass-heat transfer, that can be used by laser flow loop designers.

BLSS: A Contribution to Future Life Support

NASA Technical Reports Server (NTRS)

Skoog, A. I.

1985-01-01

The problem of the supply of basic life supporting ingredients was analyzed. Storage volume and launch weight of water, oxygen and food in a conventional nonregenerable life support system are directly proportional to the crew size and the length of the mission. Because of spacecraft payload limitations this requires that the carbon, or food, recycling loop, the third and final part in the life support system, be closed to further reduce logistics cost. Advanced life support systems need to be developed in which metabolic waste products are regenerated and food is produced. Biological life support systems (BLSS) satisfy the space station environmental control functions and close the food cycle. Numerous scientific space experiments were delineated, the results of which are applicable to the support of BLSS concepts. Requirements and concepts are defined and the feasibility of BLSS for space application are analyzed. The BLSS energy mass relation, and the possibilities to influence it to achieve advantages for the BLSS are determined. A program for the development of BLSS is proposed.

An optimal open/closed-loop control method with application to a pre-stressed thin duralumin plate

NASA Astrophysics Data System (ADS)

Nadimpalli, Sruthi Raju

The excessive vibrations of a pre-stressed duralumin plate, suppressed by a combination of open-loop and closed-loop controls, also known as open/closed-loop control, is studied in this thesis. The two primary steps involved in this process are: Step (I) with an assumption that the closed-loop control law is proportional, obtain the optimal open-loop control by direct minimization of the performance measure consisting of energy at terminal time and a penalty on open-loop control force via calculus of variations. If the performance measure also involves a penalty on closed-loop control effort then a Fourier based method is utilized. Step (II) the energy at terminal time is minimized numerically to obtain optimal values of feedback gains. The optimal closed-loop control gains obtained are used to describe the displacement and the velocity of open-loop, closed-loop and open/closed-loop controlled duralumin plate.

Advanced physical-chemical life support systems research

NASA Technical Reports Server (NTRS)

Evanich, Peggy L.

1988-01-01

A proposed NASA space research and technology development program will provide adequate data for designing closed loop life support systems for long-duration manned space missions. This program, referred to as the Pathfinder Physical-Chemical Closed Loop Life Support Program, is to identify and develop critical chemical engineering technologies for the closure of air and water loops within the spacecraft, surface habitats or mobility devices. Computerized simulation can be used both as a research and management tool. Validated models will guide the selection of the best known applicable processes and in the development of new processes. For the integration of the habitat system, a biological subsystem would be introduced to provide food production and to enhance the physical-chemical life support functions on an ever-increasing basis.

Plant Biomass Leaching for Nutrient Recovery in Closed Loop Systems Project

NASA Technical Reports Server (NTRS)

Zeitlin, Nancy P.; Wheeler, Raymond (Compiler); Lunn, Griffin

2015-01-01

Plants will be important for food and O2 production during long term human habitation in space. Recycling of nutrients (e.g., from waste materials) could reduce the resupply costs of fertilizers for growing these plants. Work at NASA's Kennedy Space Center has shown that ion exchange resins can extract fertilizer (plant essential nutrients) from human waste water, after which the residual brine could be treated with electrodialysis to recover more water and produce high value chemicals (e.g., acids and bases). In habitats with significant plant production, inedible biomass becomes a major source of solid waste. To "close the loop" we also need to recover useful nutrients and fertilizer from inedible biomass. We are investigating different approaches to retrieve nutrients from inedible plant biomass, including physical leaching with water, processing the biomass in bioreactors, changing the pH of leaching processing, and/or conducting multiple leaches of biomass residues.

Putting one step before the other: distinct activation pathways for Cdk1 and Cdk2 bring order to the mammalian cell cycle

PubMed Central

Merrick, Karl A.; Fisher, Robert P.

2010-01-01

Eukaryotic cell division is controlled by the activity of cyclin-dependent kinases (CDKs). Cdk1 and Cdk2, which function at different stages of the mammalian cell cycle, both require cyclin-binding and phosphorylation of the activation (T-) loop for full activity, but differ with respect to the order in which the two steps occur in vivo. To form stable complexes with either of its partners—cyclins A and B—Cdk1 must be phosphorylated on its T-loop, but that phosphorylation in turn depends on the presence of cyclin. Cdk2 can follow a kinetically distinct path to activation in which T-loop phosphorylation precedes cyclin-binding, and thereby out-compete the more abundant Cdk1 for limiting amounts of cyclin A. Mathematical modeling suggests this could be a principal basis for the temporal ordering of CDK activation during S phase, which may dictate the sequence in which replication origins fire. Still to be determined are how: 1) the activation machinery discriminates between closely related CDKs, and 2) coordination of the cell cycle is affected when this mechanism of pathway insulation breaks down. PMID:20139727

Approaches to lunar base life support

NASA Technical Reports Server (NTRS)

Brown, M. F.; Edeen, M. A.

1990-01-01

Various approaches to reliable, low maintenance, low resupply regenerative long-term life support for lunar base application are discussed. The first approach utilizes Space Station Freedom physiochemical systems technology which has closed air and water loops with approximately 99 and 90 percent closure respectively, with minor subsystem changes to the SSF baseline improving the level of water resupply for the water loop. A second approach would be a physiochemical system, including a solid waste processing system and improved air and water loop closure, which would require only food and nitrogen for resupply. A hybrid biological/physiochemical life support system constitutes the third alternative, incorporating some level of food production via plant growth into the life support system. The approaches are described in terms of mass, power, and resupply requirements; and the potential evolution of a small, initial outpost to a large, self-sustaining base is discussed.

Achieving Change through Reflective Practice: Closing the Loop.

ERIC Educational Resources Information Center

Page, Susie; Meerabeau, Liz

2000-01-01

A study in which reflection was used to identify nurses' learning needs regarding cardiopulmonary resuscitation found that an unexpected outcome of reflection was "apathy": action issues were not prioritized or acted upon. In order to effect changes in practice, planning and management of change should be part of the reflective cycle.…

Managing a closed-loop supply chain inventory system with learning effects

NASA Astrophysics Data System (ADS)

Jauhari, Wakhid Ahmad; Dwicahyani, Anindya Rachma; Hendaryani, Oktiviandri; Kurdhi, Nughthoh Arfawi

2018-02-01

In this paper, we propose a closed-loop supply chain model consisting of a retailer and a manufacturer. We intend to investigate the impact of learning in regular production, remanufacturing and reworking. The customer demand is assumed deterministic and will be satisfied from both regular production and remanufacturing process. The return rate of used items depends on quality. We propose a mathematical model with the objective is to maximize the joint total profit by simultaneously determining the length of ordering cycle for the retailer and the number of regular production and remanufacturing cycle. The algorithm is suggested for finding the optimal solution. A numerical example is presented to illustrate the application of using a proposed model. The results show that the integrated model performs better in reducing total cost compared to the independent model. The total cost is most affected by the changes in the values of unit production cost and acceptable quality level. In addition, the changes in the defective items proportion and the fraction of holding costs significantly influence the retailer's ordering period.

Low chemical concentrating steam generating cycle

DOEpatents

Mangus, James D.

1983-01-01

A steam cycle for a nuclear power plant having two optional modes of operation. A once-through mode of operation uses direct feed of coolant water to an evaporator avoiding excessive chemical concentration buildup. A recirculation mode of operation uses a recirculation loop to direct a portion of flow from the evaporator back through the evaporator to effectively increase evaporator flow.

A Closed Loop System Using a Brine Reservoir to Replace Fresh Water as the Frac Fluid Source

EPA Pesticide Factsheets

A non-fresh water source, the Debolt formation, has been proposed and tested in the laboratory and field for application as a fracturing fluid in shale gas formations, with potential to replace much of the fresh water used in the Horn River Basin.

Effects of protonation state of Asp181 and position of active site water molecules on the conformation of PTP1B.

PubMed

Ozcan, Ahmet; Olmez, Elif Ozkirimli; Alakent, Burak

2013-05-01

In protein tyrosine phosphatase 1B (PTP1B), the flexible WPD loop adopts a closed conformation (WPDclosed ) in the active state of PTP1B, bringing the catalytic Asp181 close to the active site pocket, while WPD loop is in an open conformation (WPDopen ) in the inactive state. Previous studies showed that Asp181 may be protonated at physiological pH, and ordered water molecules exist in the active site. In the current study, molecular dynamics simulations are employed at different Asp181 protonation states and initial positions of active site water molecules, and compared with the existing crystallographic data of PTP1B. In WPDclosed conformation, the active site is found to maintain its conformation only in the protonated state of Asp181 in both free and liganded states, while Asp181 is likely to be deprotonated in WPDopen conformation. When the active site water molecule network that is a part of the free WPDclosed crystal structure is disrupted, intermediate WPD loop conformations, similar to that in the PTPRR crystal structure, are sampled in the MD simulations. In liganded PTP1B, one active site water molecule is found to be important for facilitating the orientation of Cys215 and the phosphate ion, thus may play a role in the reaction. In conclusion, conformational stability of WPD loop, and possibly catalytic activity of PTP1B, is significantly affected by the protonation state of Asp181 and position of active site water molecules, showing that these aspects should be taken into consideration both in MD simulations and inhibitor design. Copyright © 2013 Wiley Periodicals, Inc.

Closed Field Coronal Heating Models Inspired by Wave Turbulence

NASA Astrophysics Data System (ADS)

Downs, C.; Lionello, R.; Mikic, Z.; Linker, J.; Velli, M. M.

2013-12-01

To simulate the energy balance of coronal plasmas on macroscopic scales, we often require the specification of the coronal heating mechanism in some functional form. To go beyond empirical formulations and to build a more physically motivated heating function, we investigate the wave-turbulence dissipation (WTD) phenomenology for the heating of closed coronal loops. To do so, we employ an implementation of non-WKB equations designed to capture the large-scale propagation, reflection, and dissipation of wave turbulence along a loop. The parameter space of this model is explored by solving the coupled WTD and hydrodynamic equations in 1D for an idealized loop, and the relevance to a range of solar conditions is established by computing solutions for several hundred loops extracted from a realistic 3D coronal field. Due to the implicit dependence of the WTD heating model on loop geometry and plasma properties along the loop and at the footpoints, we find that this model can significantly reduce the number of free parameters when compared to traditional empirical heating models, and still robustly describe a broad range of quiet-sun and active region conditions. The importance of the self-reflection term in producing realistic heating scale heights and thermal non-equilibrium cycles is discussed, and preliminary 3D thermodynamic MHD simulations using this formulation are presented. Research supported by NASA and NSF.

Dynamic analysis of concentrated solar supercritical CO2-based power generation closed-loop cycle

DOE PAGES

Osorio, Julian D.; Hovsapian, Rob; Ordonez, Juan C.

2016-01-01

Here, the dynamic behavior of a concentrated solar power (CSP) supercritical CO 2 cycle is studied under different seasonal conditions. The system analyzed is composed of a central receiver, hot and cold thermal energy storage units, a heat exchanger, a recuperator, and multi-stage compression-expansion subsystems with intercoolers and reheaters between compressors and turbines respectively. Energy models for each component of the system are developed in order to optimize operating and design parameters such as mass flow rate, intermediate pressures and the effective area of the recuperator to lead to maximum efficiency. Our results show that the parametric optimization leads themore » system to a process efficiency of about 21 % and a maximum power output close to 1.5 MW. The thermal energy storage allows the system to operate for several hours after sunset. This operating time is approximately increased from 220 to 480 minutes after optimization. The hot and cold thermal energy storage also lessens the temperature fluctuations by providing smooth changes of temperatures at the turbines and compressors inlets. Our results indicate that concentrated solar systems using supercritical CO 2 could be a viable alternative to satisfying energy needs in desert areas with scarce water and fossil fuel resources.« less

[Design of medical devices management system supporting full life-cycle process management].

PubMed

Su, Peng; Zhong, Jianping

2014-03-01

Based on the analysis of the present status of medical devices management, this paper optimized management process, developed a medical devices management system with Web technologies. With information technology to dynamic master the use of state of the entire life-cycle of medical devices. Through the closed-loop management with pre-event budget, mid-event control and after-event analysis, improved the delicacy management level of medical devices, optimized asset allocation, promoted positive operation of devices.

Closed-Loop Control Better than Open-Loop Control of Profofol TCI Guided by BIS: A Randomized, Controlled, Multicenter Clinical Trial to Evaluate the CONCERT-CL Closed-Loop System

PubMed Central

Zhang, Xuena; Wu, Anshi; Yao, Shanglong; Xue, Zhanggang; Yue, Yun

2015-01-01

Background The CONCERT-CL closed-loop infusion system designed by VERYARK Technology Co., Ltd. (Guangxi, China) is an innovation using TCI combined with closed-loop controlled intravenous anesthesia under the guide of BIS. In this study we performed a randomized, controlled, multicenter study to compare closed-loop control and open-loop control of propofol by using the CONCERT-CL closed-loop infusion system. Methods 180 surgical patients from three medical centers undergone TCI intravenous anesthesia with propofol and remifentanil were randomly assigned to propofol closed-loop group and propofol opened-loop groups. Primary outcome was global score (GS, GS = (MDAPE+Wobble)/% of time of bispectral index (BIS) 40-60). Secondary outcomes were doses of the anesthetics and emergence time from anesthesia, such as, time to tracheal extubation. Results There were 89 and 86 patients in the closed-loop and opened-loop groups, respectively. GS in the closed-loop groups (22.21±8.50) were lower than that in the opened-loop group (27.19±15.26) (p=0.009). The higher proportion of time of BIS between 40 and 60 was also observed in the closed-loop group (84.11±9.50%), while that was 79.92±13.17% in the opened-loop group, (p=0.016). No significant differences in propofol dose and time of tracheal extubation were observed. The frequency of propofol regulation in the closed-loop group (31.55±9.46 times/hr) was obverse higher than that in the opened-loop group (6.84±6.21 times/hr) (p=0.000). Conclusion The CONCERT-CL closed-loop infusion system can automatically regulate the TCI of propofol, maintain the BIS value in an adequate range and reduce the workload of anesthesiologists better than open-loop system. Trial Registration ChiCTR ChiCTR-OOR-14005551 PMID:25886041

Low cycle fatigue properties of MAR-M-246 Hf in hydrogen. [a cast nickel-base alloy

NASA Technical Reports Server (NTRS)

Warren, J. R.

1979-01-01

The transverse, low cycle fatigue properties were determined for directionally solidified and single crystal samples of a cast nickel-base alloy proposed for use in space propulsion systems in pure or partial high pressure hydrogen environments at elevated temperatures. The test temperature was 760 C (1400F) and the pressure of the gaseous hydrogen was 34.5 MPa (5000 psig). Low cycle fatique life was established by strain controlled testing using smooth specimens and a servohydraulic closed-loop test machine modified with a high pressure environmental chamber. Results and conclusions are discussed.

Laser Cooling the Diatomic Molecule CaH

NASA Astrophysics Data System (ADS)

Velasquez, Joe, III; Di Rosa, Michael

2014-06-01

To laser-cool a species, a closed (or nearly closed) cycle is required to dissipate translational energy through many directed laser-photon absorption and subsequent randomly-directed spontaneous emission events. Many atoms lend themselves to such a closed-loop cooling cycle. Attaining laser-cooled molecular species is challenging because of their inherently complex internal structure, yet laser-cooling molecules could lead to studies in interesting chemical dynamics among other applications. Typically, laser-cooled atoms are assembled into molecules through photoassociation or Feschbach resonance. CaH is one of a few molecules whose internal structure is quite atom-like, allowing a nearly closed cycle without the need for many repumping lasers. We will also present our work-to-date on laser cooling this molecule. We employ traditional pulsed atomic/molecular beam techniques with a laser vaporization source to generate species with well-defined translational energies over a narrow range of velocity. In this way, we can apply laser-cooling to most species in the beam along a single dimension (the beam's axis). This project is funded by the LDRD program of the Los Alamos National Laboratory.

System Mass Variation and Entropy Generation in 100k We Closed-Brayton-Cycle Space Power Systems

NASA Technical Reports Server (NTRS)

Barrett, Michael J.; Reid, Bryan M.

2004-01-01

State-of-the-art closed-Brayton-cycle (CBC) space power systems were modeled to study performance trends in a trade space characteristic of interplanetary orbiters. For working-fluid molar masses of 48.6, 39.9, and 11.9 kg/kmol, peak system pressures of 1.38 and 3.0 MPa and compressor pressure ratios ranging from 1.6 to 2.4, total system masses were estimated. System mass increased as peak operating pressure increased for all compressor pressure ratios and molar mass values examined. Minimum mass point comparison between 72 percent He at 1.38 MPa peak and 94 percent He at 3.0 MPa peak showed an increase in system mass of 14 percent. Converter flow loop entropy generation rates were calculated for 1.38 and 3.0 MPa peak pressure cases. Physical system behavior was approximated using a pedigreed NASA Glenn modeling code, Closed Cycle Engine Program (CCEP), which included realistic performance prediction for heat exchangers, radiators and turbomachinery.

System Mass Variation and Entropy Generation in 100-kWe Closed-Brayton-Cycle Space Power Systems

NASA Technical Reports Server (NTRS)

Barrett, Michael J.; Reid, Bryan M.

2004-01-01

State-of-the-art closed-Brayton-cycle (CBC) space power systems were modeled to study performance trends in a trade space characteristic of interplanetary orbiters. For working-fluid molar masses of 48.6, 39.9, and 11.9 kg/kmol, peak system pressures of 1.38 and 3.0 MPa and compressor pressure ratios ranging from 1.6 to 2.4, total system masses were estimated. System mass increased as peak operating pressure increased for all compressor pressure ratios and molar mass values examined. Minimum mass point comparison between 72 percent He at 1.38 MPa peak and 94 percent He at 3.0 MPa peak showed an increase in system mass of 14 percent. Converter flow loop entropy generation rates were calculated for 1.38 and 3.0 MPa peak pressure cases. Physical system behavior was approximated using a pedigreed NASA Glenn modeling code, Closed Cycle Engine Program (CCEP), which included realistic performance prediction for heat exchangers, radiators and turbomachinery.

Spelling Lesson: Tetratecture.

ERIC Educational Resources Information Center

American School and University, 1981

1981-01-01

Reedy Creek Elementary School in Kissimmee (Florida) is the state's first earth-sheltered school. The 22-inch average depth of the earth on the roof, a closed loop water source heat pump, and a solar collector system for hot water are expected to reduce energy costs by 50 percent. (Author/MLF)

Closed Cycle Magnetohydrodynamic Nuclear Space Power Generation Using Helium/Xenon Working Plasma

NASA Technical Reports Server (NTRS)

Litchford, R. J.; Harada, N.

2005-01-01

A multimegawatt-class nuclear fission powered closed cycle magnetohydrodynamic space power plant using a helium/xenon working gas has been studied, to include a comprehensive system analysis. Total plant efficiency was expected to be 55.2 percent including pre-ionization power. The effects of compressor stage number, regenerator efficiency, and radiation cooler temperature on plant efficiency were investigated. The specific mass of the power generation plant was also examined. System specific mass was estimated to be 3 kg/kWe for a net electrical output power of 1 MWe, 2-3 kg/kWe at 2 MWe, and approx.2 kg/KWe at >3 MWe. Three phases of research and development plan were proposed: (1) Phase I-proof of principle, (2) Phase II-demonstration of power generation, and (3) Phase III-prototypical closed loop test.

Linkages between terrestrial ecosystems and the atmosphere

NASA Technical Reports Server (NTRS)

Bretherton, Francis; Dickinson, Robert E.; Fung, Inez; Moore, Berrien, III; Prather, Michael; Running, Steven W.; Tiessen, Holm

1992-01-01

The primary research issue in understanding the role of terrestrial ecosystems in global change is analyzing the coupling between processes with vastly differing rates of change, from photosynthesis to community change. Representing this coupling in models is the central challenge to modeling the terrestrial biosphere as part of the earth system. Terrestrial ecosystems participate in climate and in the biogeochemical cycles on several temporal scales. Some of the carbon fixed by photosynthesis is incorporated into plant tissue and is delayed from returning to the atmosphere until it is oxidized by decomposition or fire. This slower (i.e., days to months) carbon loop through the terrestrial component of the carbon cycle, which is matched by cycles of nutrients required by plants and decomposers, affects the increasing trend in atmospheric CO2 concentration and imposes a seasonal cycle on that trend. Moreover, this cycle includes key controls over biogenic trace gas production. The structure of terrestrial ecosystems, which responds on even longer time scales (annual to century), is the integrated response to the biogeochemical and environmental constraints that develop over the intermediate time scale. The loop is closed back to the climate system since it is the structure of ecosystems, including species composition, that sets the terrestrial boundary condition in the climate system through modification of surface roughness, albedo, and, to a great extent, latent heat exchange. These separate temporal scales contain explicit feedback loops which may modify ecosystem dynamics and linkages between ecosystems and the atmosphere. The long-term change in climate, resulting from increased atmospheric concentrations of greenhouse gases (e.g., CO2, CH4, and nitrous oxide (N2O)) will further modify the global environment and potentially induce further ecosystem change. Modeling these interactions requires coupling successional models to biogeochemical models to physiological models that describe the exchange of water, energy, and biogenic trace gases between the vegetation and the atmosphere at fine time scales. There does not appear to be any obvious way to allow direct reciprocal coupling of atmospheric general circulation models (GCM's), which inherently run with fine time steps, to ecosystem or successional models, which have coarse temporal resolution, without the interposition of physiological canopy models. This is equally true for biogeochemical models of the exchange of carbon dioxide and trace gases. This coupling across time scales is nontrivial and sets the focus for the modeling strategy.

Simultaneous treatment of SO2 containing stack gases and waste water

NASA Technical Reports Server (NTRS)

Poradek, J. C.; Collins, D. D. (Inventor)

1978-01-01

A process for simultaneously removing sulfur dioxide from stack gases and the like and purifying waste water such as derived from domestic sewage is described. A portion of the gas stream and a portion of the waste water, the latter containing dissolved iron and having an acidic pH, are contacted in a closed loop gas-liquid scrubbing zone to effect absorption of the sulfur dioxide into the waste water. A second portion of the gas stream and a second portion of the waste water are controlled in an open loop gas-liquid scrubbing zone. The second portion of the waste water contains a lesser amount of iron than the first portion of the waste water. Contacting in the openloop scrubbing zone is sufficient to acidify the waste water which is then treated to remove solids originally present.

Extraction of urea and ammonium ion

NASA Technical Reports Server (NTRS)

Anselmi, R. T.; Husted, R. R.; Schulz, J. R.

1977-01-01

Water purification system keeps urea and ammonium ion concentration below toxic limits in recirculated water of closed loop aquatic habitat. Urea is first converted to ammonium ions and carbon dioxide by enzygmatic action. Ammonium ions are removed by ion exchange. Bioburden is controlled by filtration through 0.45 micron millipore filters.

Close-up view of Sodium Chloride crystals in a water bubble on Expedition Six.

NASA Image and Video Library

2003-03-14

ISS006-E-39236 (14 March 2003) --- A view of sodium chloride crystals in a water bubble within a 50-millimeter metal loop was photographed by an Expedition Six crewmember. The experiment took place in the Destiny laboratory on the International Space Station (ISS).

Bioextraction potential of seaweed in Denmark - An instrument for circular nutrient management.

PubMed

Seghetta, Michele; Tørring, Ditte; Bruhn, Annette; Thomsen, Marianne

2016-09-01

The aim of the study is to assess the efficacy of seaweed for circular nutrient management to reduce eutrophication levels in the aquatic environment. We performed a comparative Life Cycle Assessment (LCA) of two reference waste management systems treating seaweed as biowaste, i.e. landfill disposal and combustion, and an alternative scenario using the seaweed Saccharina latissima as a resource for biobased fertilizer production. Life Cycle Impact Assessment (LCIA) methods were improved by using a cradle-to-cradle approach, quantifying fate factors for nitrogen and phosphorus loss from fertilized agriculture to the aquatic environment. We also differentiated between nitrogen- and phosphorus-limited marine water to improve the traditional freshwater impact category, making this indicator suitable for decision support in relation to coastal water management schemes. Offshore cultivation of Saccharina latissima with an average productivity of 150Mg/km(2) in Danish waters in 2014 was applied to a cultivation scenario of 208km(2). The bioresource scenario performs better than conventional biowaste management systems, delivering a net reduction in aquatic eutrophication levels of 32.29kgNeq. and 16.58kgPO4(3-)eq. per Mg (dry weight) of seaweed, quantified by the ReCiPe and CML impact assessment methods, respectively. Seaweed cultivation, harvest and reuse of excess nutrients from the aquatic environment is a promising approach for sustainable resource cycling in a future regenerative economy that exploits manmade emissions as a resource for closed loop biobased production while significantly reducing eutrophication levels in 3 out of 7 Danish river basin districts. We obtained at least 10% bioextraction of phosphorus manmade emissions (10%, 89% and >100%) and contributed significantly to local nitrogen reduction goals according to the Water Framework Directive (23%, 78% and >100% of the target). Copyright © 2016 Elsevier B.V. All rights reserved.

Life cycle assessment of bottled water: A case study of Green2O products.

PubMed

Horowitz, Naomi; Frago, Jessica; Mu, Dongyan

2018-06-01

This study conducted a full life cycle analysis of bottled water on four types of bottles: ENSO, PLA (corn based), recycled PET, and regular (petroleum based) PET, to discern which bottle material is more beneficial to use in terms of environmental impacts. PET bottles are the conventional bottles used that are not biodegradable and accumulate in landfills. PLA corn based bottles are derived from an organic substance and are degradable under certain environmental conditions. Recycled PET bottles are purified PET bottles that were disposed of and are used in a closed loop system. An ENSO bottle contains a special additive which is designed to help the plastic bottle degrade after disposed of in a landfill. The results showed that of all fourteen impact categories examined, the recycled PET and ENSO bottles were generally better than the PLA and regular PET bottles; however, the ENSO had the highest impacts in the categories of global warming and respiratory organics, and the recycled PET had the highest impact in the eutrophication category. The life cycle stages that were found to have the highest environmental impacts were the bottle manufacturing stage and the bottled water distribution to storage stage. Analysis of the mixed bottle material based on recycled PET resin and regular PET resin was discussed as well, in which key impact categories were identified. The PLA bottle contained extremely low impacts in the carcinogens, respiratory organics and global warming categories, yet it still contained the highest impacts in seven of the fourteen categories. Overall, the results demonstrate that the usage of more sustainable bottles, such as biodegradable ENSO bottles and recycled PET bottles, appears to be a viable option for decreasing impacts of the bottled water industry on the environment. Published by Elsevier Ltd.

A limit-cycle self-organizing map architecture for stable arm control.

PubMed

Huang, Di-Wei; Gentili, Rodolphe J; Katz, Garrett E; Reggia, James A

2017-01-01

Inspired by the oscillatory nature of cerebral cortex activity, we recently proposed and studied self-organizing maps (SOMs) based on limit cycle neural activity in an attempt to improve the information efficiency and robustness of conventional single-node, single-pattern representations. Here we explore for the first time the use of limit cycle SOMs to build a neural architecture that controls a robotic arm by solving inverse kinematics in reach-and-hold tasks. This multi-map architecture integrates open-loop and closed-loop controls that learn to self-organize oscillatory neural representations and to harness non-fixed-point neural activity even for fixed-point arm reaching tasks. We show through computer simulations that our architecture generalizes well, achieves accurate, fast, and smooth arm movements, and is robust in the face of arm perturbations, map damage, and variations of internal timing parameters controlling the flow of activity. A robotic implementation is evaluated successfully without further training, demonstrating for the first time that limit cycle maps can control a physical robot arm. We conclude that architectures based on limit cycle maps can be organized to function effectively as neural controllers. Copyright © 2016 Elsevier Ltd. All rights reserved.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chatterton, Mike

The Recovery Act: Districtwide Geothermal Heating Conversion project performed by the Blaine County School District was part of a larger effort by the District to reduce operating costs, address deferred maintenance items, and to improve the learning environment of the students. This project evaluated three options for the ground source which were Open-Loop Extraction/Re-injection wells, Closed-Loop Vertical Boreholes, and Closed-Loop Horizontal Slinky approaches. In the end the Closed-Loop Horizontal Slinky approach had the lowest total cost of ownership but the majority of the sites associated with this project did not have enough available ground area to install the system somore » the second lowest option was used (Open-Loop). In addition to the ground source, this project looked at ways to retrofit existing HVAC systems with new high efficiency systems. The end result was the installation of distributed waterto- air heat pumps with water-to-water heat pumps installed to act as boilers/chillers for areas with a high ventilation demand such as they gymnasiums. A number of options were evaluated and the lowest total cost of ownership approach was implemented in the majority of the facilities. The facilities where the lowest total cost of ownership approaches was not selected were done to maintain consistency of the systems from facility to facility. This project had a number of other benefits to the Blaine County public. The project utilizes guaranteed energy savings to justify the levy funds expended. The project also developed an educational dashboard that can be used in the classrooms and to educate the community on the project and its performance. In addition, the majority of the installation work was performed by contractors local to Blaine County which acted as an economic stimulus to the area during a period of recession.« less

Nonazeotropic Heat Pump

NASA Technical Reports Server (NTRS)

Ealker, David H.; Deming, Glenn

1991-01-01

Heat pump collects heat from water circulating in heat-rejection loop, raises temperature of collected heat, and transfers collected heat to water in separate pipe. Includes sealed motor/compressor with cooling coils, evaporator, and condenser, all mounted in outer housing. Gradients of temperature in evaporator and condenser increase heat-transfer efficiency of vapor-compression cycle. Intended to recover relatively-low-temperature waste heat and use it to make hot water.

CLOSED-LOOP STRIPPING ANALYSIS (CLSA) OF ...

EPA Pesticide Factsheets

Synthetic musk compounds have been found in surface water, fish tissues, and human breast milk. Current techniques for separating these compounds from fish tissues require tedious sample clean-upprocedures A simple method for the deterrnination of these compounds in fish tissues has been developed. Closed-loop stripping of saponified fish tissues in a I -L Wheaton purge-and-trap vessel is used to strip compounds with high vapor pressures such as synthetic musks from the matrix onto a solid sorbent (Abselut Nexus). This technique is useful for screening biological tissues that contain lipids for musk compounds. Analytes are desorbed from the sorbent trap sequentially with polar and nonpolar solvents, concentrated, and directly analyzed by high resolution gas chromatography coupled to a mass spectrometer operating in the selected ion monitoring mode. In this paper, we analyzed two homogenized samples of whole fish tissues with spiked synthetic musk compounds using closed-loop stripping analysis (CLSA) and pressurized liquid extraction (PLE). The analytes were not recovered quantitatively but the extraction yield was sufficiently reproducible for at least semi-quantitative purposes (screening). The method was less expensive to implement and required significantly less sample preparation than the PLE technique. The research focused on in the subtasks is the development and application of state-of the-art technologies to meet the needs of the public, Office of Water,

The Physical/Chemical Closed-Loop Life Support Research Project

NASA Technical Reports Server (NTRS)

Bilardo, Vincent J., Jr.

1990-01-01

The various elements of the Physical/Chemical Closed-Loop Life Support Research Project (P/C CLLS) are described including both those currently funded and those planned for implementation at ARC and other participating NASA field centers. The plan addresses the entire range of regenerative life support for Space Exploration Initiative mission needs, and focuses initially on achieving technology readiness for the Initial Lunar Outpost by 1995-97. Project elements include water reclamation, air revitalization, solid waste management, thermal and systems control, and systems integration. Current analysis estimates that each occupant of a space habitat will require a total of 32 kg/day of supplies to live and operate comfortably, while an ideal P/C CLLS system capable of 100 percent reclamation of air and water, but excluding recycling of solid wastes or foods, will reduce this requirement to 3.4 kg/day.

Partial synchronization of relaxation oscillators with repulsive coupling in autocatalytic integrate-and-fire model and electrochemical experiments

NASA Astrophysics Data System (ADS)

Kori, Hiroshi; Kiss, István Z.; Jain, Swati; Hudson, John L.

2018-04-01

Experiments and supporting theoretical analysis are presented to describe the synchronization patterns that can be observed with a population of globally coupled electrochemical oscillators close to a homoclinic, saddle-loop bifurcation, where the coupling is repulsive in the electrode potential. While attractive coupling generates phase clusters and desynchronized states, repulsive coupling results in synchronized oscillations. The experiments are interpreted with a phenomenological model that captures the waveform of the oscillations (exponential increase) followed by a refractory period. The globally coupled autocatalytic integrate-and-fire model predicts the development of partially synchronized states that occur through attracting heteroclinic cycles between out-of-phase two-cluster states. Similar behavior can be expected in many other systems where the oscillations occur close to a saddle-loop bifurcation, e.g., with Morris-Lecar neurons.

SELF-ORGANIZATION OF RECONNECTING PLASMAS TO MARGINAL COLLISIONALITY IN THE SOLAR CORONA

DOE Office of Scientific and Technical Information (OSTI.GOV)

Imada, S.; Zweibel, E. G.

We explore the suggestions by Uzdensky and Cassak et al. that coronal loops heated by magnetic reconnection should self-organize to a state of marginal collisionality. We discuss their model of coronal loop dynamics with a one-dimensional hydrodynamic calculation. We assume that many current sheets are present, with a distribution of thicknesses, but that only current sheets thinner than the ion skin depth can rapidly reconnect. This assumption naturally causes a density-dependent heating rate which is actively regulated by the plasma. We report nine numerical simulation results of coronal loop hydrodynamics in which the absolute values of the heating rates aremore » different but their density dependences are the same. We find two regimes of behavior, depending on the amplitude of the heating rate. In the case that the amplitude of heating is below a threshold value, the loop is in stable equilibrium. Typically, the upper and less dense part of a coronal loop is collisionlessly heated and conductively cooled. When the amplitude of heating is above the threshold, the conductive flux to the lower atmosphere required to balance collisionless heating drives an evaporative flow which quenches fast reconnection, ultimately cooling and draining the loop until the cycle begins again. The key elements of this cycle are gravity and the density dependence of the heating function. Some additional factors are present, including pressure-driven flows from the loop top, which carry a large enthalpy flux and play an important role in reducing the density. We find that on average the density of the system is close to the marginally collisionless value.« less

Influence of acid rain upon water plumbosolvency.

PubMed Central

Moore, M R

1985-01-01

The West of Scotland has had particular problems in the past associated with soft acidic water supplies and uptake of lead from domestic plumbing systems by such water. As a consequence of this, health problems related to overexposure to lead have been identified. The current debate on acidification of ground waters by acid rain is therefore particularly pertinent to this area. Studies have shown that even a modest decrease in pH will result in very substantial increase in plumbosolvency. This was found to be of particular importance in the city of Glasgow and town of Ayr, where prior to water treatment, pH values were 6.3 and 5.4, respectively, and where, consequentially, large numbers of homes did not comply with lead in water standards. Closed-loop lime-dosing systems were introduced in both Glasgow and Ayr to increase the pH with immediate decrease in the lead content of the water and, subsequently, blood lead concentrations of the subjects living in these areas. Such closed-loop systems will compensate for any acidity in water supplies, whether of natural origin or originating from acid rain precipitation. However, when such treatment has not been applied, any increase in water acidity due to acid rain which is, in many cases, already unacceptable. which is, in many cases, already unacceptable. PMID:4076078

New mud system produces solids-free, reusable water

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1996-02-01

The Corpus Christi, Texas, based Cameron Equipment Co., Inc., has developed a closed-loop mud treating system that removes solids from water-based systems and leaves the separated fluid clean and chemical free enough to be re-used directly on the rig. The system has been successfully applied by a Gulf of Mexico operator in areas where zero discharge is required. The alternative mud conditions program offered by the developers is called the Cameron Fluid Recycling System. Designed for closed-loop water-based fluids, the system is a new method of removing solids from normally discharged fluids such as drilling mud, waste and wash water,more » or any other water-based fluid that contains undesirable solids. The patented method efficiently produces end products that are (1) dry solids; and (2) essentially 100% solids-free fluid that can be re-used in the same mud system. All excess drilling mud, and all wash water that would normally go to the reserve pit or a cuttings barge are collected in a tank. Recycled fluid is compatible with the mud system fluid, no harmful chemicals are used, and pH is not altered.« less

Determination of musks and other fragrance compounds at ng/L levels using CLSA (closed loop stripping analysis) and GC/MS detection.

PubMed

Mitjans, D; Ventura, F

2004-01-01

Closed loop stripping analysis (CLSA), a suitable tool for the determination of volatile and semivolatile compounds at low trace levels (ng/l), has been used to determine and quantify seven selected musks and two fragrances (Acetyl cedrene and Amberonne). The obtained extracts are analyzed by high resolution gas chromatography coupled to mass spectrometry (GC/MS) operating in the SIM mode. Quality parameters such as limit of detection; matrix effects; precision expressed as repeatability and reproducibility relative standard deviations of the method and an estimation of the uncertainty have been evaluated. The method has been applied to the analysis of wastewater effluents, surface water and tap water from different places in Europe. All samples contained differents musks at ng/l levels with the polycyclic musks Galaxolide and Tonalide and both fragrances, Amberonne and Acetyl cedrene, being the most abundant. These results suggest the importance of studying and controlling the presence of these ubiquitous environmental compounds in water systems.

The Orion Atmosphere Revitalization Technology in Manned Ambient Pressure Space Suit Testing

NASA Technical Reports Server (NTRS)

Button, Amy; Sweterlitsch, Jeffrey

2011-01-01

An amine-based carbon dioxide (CO2) and water vapor sorbent in pressure-swing regenerable beds has been developed by Hamilton Sundstrand and baselined for the Atmosphere Revitalization System (ARS) for moderate duration missions of the Orion Multipurpose Crew Vehicle. The Orion ARS is designed to support not only open-cabin operations, tests of which have been reported in previous years at this conference, but also closed space suit-loop operations. A previous low-pressure suit loop test was performed with a human metabolic simulator, and humans wearing emergency masks were tested in a closed-loop configuration before that. In late 2011, simple tests were performed in a suit-loop configuration with human test subjects in prototype space suits with prototype umbilicals at ambient and two slightly above-ambient pressures. Trace contaminant filters and a prototype blower were also incorporated into the test rig. This paper discusses the performance of the ARS technology in that 2011 test configuration.

Solar heating and hot water system installed at Arlington Raquetball Club, Arlington, Virginia

NASA Technical Reports Server (NTRS)

1981-01-01

A solar space and water heating system is described. The solar energy system consists of 2,520 sq. ft. of flat plate solar collectors and a 4,000 gallon solar storage tank. The transfer medium in the forced closed loop is a nontoxic antifreeze solution (50 percent water, 50 percent propylene glycol). The service hot water system consists of a preheat coil (60 ft. of 1 1/4 in copper tubing) located in the upper third of the solar storage tank and a recirculation loop between the preheat coil and the existing electric water heaters. The space heating system consists of two separate water to air heat exchangers located in the ducts of the existing space heating/cooling systems. The heating water is supplied from the solar storage tank. Extracts from site files, specification references for solar modifications to existing building heating and hot water systems, and installation, operation and maintenance instructions are included.

Superheat recovery system shakes savings out of A/C systems

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1985-09-01

One of the most productive and least expensive methods of recovering waste heat is a system that reclaims the excess energy or superheat generated by closed-loop-air conditioning or refrigeration cycles. Installed recently in 72 Steak N' Shakes restaurants as part of a total energy conservation package, it has helped cut gas bills by more than 70%.

A minimal mathematical model combining several regulatory cycles from the budding yeast cell cycle.

PubMed

Sriram, K; Bernot, G; Képès, F

2007-11-01

A novel topology of regulatory networks abstracted from the budding yeast cell cycle is studied by constructing a simple nonlinear model. A ternary positive feedback loop with only positive regulations is constructed with elements that activates the subsequent element in a clockwise fashion. A ternary negative feedback loop with only negative regulations is constructed with the elements that inhibit the subsequent element in an anticlockwise fashion. Positive feedback loop exhibits bistability, whereas the negative feedback loop exhibits limit cycle oscillations. The novelty of the topology is that the corresponding elements in these two homogeneous feedback loops are linked by the binary positive feedback loops with only positive regulations. This results in the emergence of mixed feedback loops in the network that displays complex behaviour like the coexistence of multiple steady states, relaxation oscillations and chaos. Importantly, the arrangement of the feedback loops brings in the notion of checkpoint in the model. The model also exhibits domino-like behaviour, where the limit cycle oscillations take place in a stepwise fashion. As the aforementioned topology is abstracted from the budding yeast cell cycle, the events that govern the cell cycle are considered for the present study. In budding yeast, the sequential activation of the transcription factors, cyclins and their inhibitors form mixed feedback loops. The transcription factors that involve in the positive regulation in a clockwise orientation generates ternary positive feedback loop, while the cyclins and their inhibitors that involve in the negative regulation in an anticlockwise orientation generates ternary negative feedback loop. The mutual regulation between the corresponding elements in the transcription factors and the cyclins and their inhibitors generates binary positive feedback loops. The bifurcation diagram constructed for the whole system can be related to the different events of the cell cycle in terms of dynamical system theory. The checkpoint mechanism that plays an important role in different phases of the cell cycle are accounted for by silencing appropriate feedback loops in the model.

Numerical Analysis of Combined Well and Open-Closed Loops Geothermal (CWG) Systems

NASA Astrophysics Data System (ADS)

Park, Yu-Chul

2016-04-01

Open-loop geothermal heat pump (GHP) system and closed-loop heat pump systems have been used in Korea to reduce emission of greenhouse gases such as carbon dioxide (CO2). The GHP systems have the pros and cons, for example, the open-loop GHP system is good energy-efficient and the closed-loop GHP system requires minimum maintenance costs. The open-loop GHP system can be used practically only with large amount of groundwater supply. The closed-loop GHP system can be used with high costs of initial installation. The performance and efficiency of the GHP system depend on the characteristics of the GHP system itself in addition to the geologic conditions. To overcome the cons of open-loop or closed-loop GHP system, the combined well and open-closed loops geothermal (CWG) system was designed. The open-loop GHP system is surrounded with closed-loop GHP systems in the CWG system. The geothermal energy in closed-loop GHP systems is supplied by the groundwater pumped by the open-loop GHP system. In this study, 2 different types of the CWG systems (small aperture hybrid CWG system and large aperture CWG system) are estimated using numerical simulation models in the aspect of energy efficiency. This work was supported by the New & Renewable Energy Core Technology Program of the Korea Institute of Energy Technology Evaluation and Planning (KETEP), granted financial resource from the Ministry of Trade, Industry & Energy, Republic of Korea. (No.20153030111120).

Potential and benefits of closed loop ECLS systems on the ISS.

PubMed

Raatschen, W; Preiss, H

2001-01-01

To close open loops for long manned missions in space is a big challenge for aeronautic engineers throughout the world. The paper's focus is on the oxygen reclamation from carbon dioxide within a space habitat. A brief description of the function principle of a fixed alkaline electrolyzer, a solid amine carbon dioxide concentrator and a Sabatier reactor is given. By combining these devices to an air revitalization system the technical and economical benefits are explained. Astrium's Air Revitalization System (ARES) as a potential future part of the International Space Station's Environmental Control and Life Support System would close the oxygen loop. The amount of oxygen, needed for an ISS crew of seven astronauts could be provided by ARES. The upload of almost 1500 kg of water annually for oxygen generation through the onboard electrolyzer would be reduced by more than 1000 kg, resulting in savings of more than 30M$ per year. Additionally, the payload capacity of supply flights would be increased by this amount of mass. Further possibilities are addressed to combine ECLS mass flows with those of the power, propulsion and attitude control systems. Such closed loop approaches will contribute to ease long time missions (e. g. Mars, Moon) from a cost and logistic point of view. The hardware realization of Astrium's space-sized operating ARES is shown and test results of continuous and intermittent closed chamber tests are presented. c2001 Astrium GmbH. Published by Elsevier Science Ltd.

Mechanical-thermal noise in drive-mode of a silicon micro-gyroscope.

PubMed

Yang, Bo; Wang, Shourong; Li, Hongsheng; Zhou, Bailing

2009-01-01

A new closed-loop drive scheme which decouples the phase and the gain of the closed-loop driving system was designed in a Silicon Micro-Gyroscope (SMG). We deduce the system model of closed-loop driving and use stochastic averaging to obtain an approximate "slow" system that clarifies the effect of thermal noise. The effects of mechanical-thermal noise on the driving performance of the SMG, including the noise spectral density of the driving amplitude and frequency, are derived. By calculating and comparing the noise amplitude due to thermal noise both in the opened-loop driving and in the closed-loop driving, we find that the closed-loop driving does not reduce the RMS noise amplitude. We observe that the RMS noise frequency can be reduced by increasing the quality factor and the drive amplitude in the closed-loop driving system. The experiment and simulation validate the feasibility of closed-loop driving and confirm the validity of the averaged equation and its stablility criterion. The experiment and simulation results indicate the electrical noise of closed-loop driving circuitry is bigger than the mechanical-thermal noise and as the driving mass decreases, the mechanical-thermal noise may get bigger than the electrical noise of the closed-loop driving circuitry.

Ultrafast pulse lasers jump to macro applications

NASA Astrophysics Data System (ADS)

Griebel, Martin; Lutze, Walter; Scheller, Torsten

2016-03-01

Ultrafast Lasers have been proven for several micro applications, e.g. stent cutting, for many years. Within its development of applications Jenoptik has started to use ultrafast lasers in macro applications in the automotive industry. The JenLas D2.fs-lasers with power output control via AOM is an ideal tool for closed loop controlled material processing. Jenoptik enhanced his well established sensor controlled laser weakening process for airbag covers to a new level. The patented process enables new materials using this kind of technology. One of the most sensitive cover materials is genuine leather. As a natural product it is extremely inhomogeneous and sensitive for any type of thermal load. The combination of femtosecond pulse ablation and closed loop control by multiple sensor array opens the door to a new quality level of defined weakening. Due to the fact, that the beam is directed by scanning equipment the process can be split in multiple cycles additionally reducing the local energy input. The development used the 5W model as well as the latest 10W release of JenLas D2.fs and achieved amazing processing speeds which directly fulfilled the requirements of the automotive industry. Having in mind that the average cycle time of automotive processes is about 60s, trials had been done of processing weakening lines in genuine leather of 1.2mm thickness. Parameters had been about 15 cycles with 300mm/s respectively resulting in an average speed of 20mm/s and a cycle time even below 60s. First samples had already given into functional and aging tests and passed successfully.

The Electron Runaround: Understanding Electric Circuit Basics through a Classroom Activity

ERIC Educational Resources Information Center

Singh, Vandana

2010-01-01

Several misconceptions abound among college students taking their first general physics course, and to some extent pre-engineering physics students, regarding the physics and applications of electric circuits. Analogies used in textbooks, such as those that liken an electric circuit to a piped closed loop of water driven by a water pump, do not…

Closing the Loop on Space Waste

NASA Astrophysics Data System (ADS)

Meier, A. J.; Hintze, P. E.

2018-02-01

A heat transfer study of mission mixed waste streams in a reactor hot zone, along with solid, tar, and water recovery. This research enables reliability and benefit on waste conversion systems to manage our environmental impact, on- and off-Earth.

Recuperative supercritical carbon dioxide cycle

DOEpatents

Sonwane, Chandrashekhar; Sprouse, Kenneth M; Subbaraman, Ganesan; O'Connor, George M; Johnson, Gregory A

2014-11-18

A power plant includes a closed loop, supercritical carbon dioxide system (CLS-CO.sub.2 system). The CLS-CO.sub.2 system includes a turbine-generator and a high temperature recuperator (HTR) that is arranged to receive expanded carbon dioxide from the turbine-generator. The HTR includes a plurality of heat exchangers that define respective heat exchange areas. At least two of the heat exchangers have different heat exchange areas.

Methodology for Software Reliability Prediction. Volume 1.

DTIC Science & Technology

1987-11-01

SPACECRAFT 0 MANNED SPACECRAFT B ATCH SYSTEM AIRBORNE AVIONICS 0 UNMANNED EVENT C014TROL a REAL TIME CLOSED 0 UNMANNED SPACECRAFT LOOP OPERATINS SPACECRAFT...software reliability. A Software Reliability Measurement Framework was established which spans the life cycle of a software system and includes the...specification, prediction, estimation, and assessment of software reliability. Data from 59 systems , representing over 5 million lines of code, were

Note: A dual temperature closed loop batch reactor for determining the partitioning of trace gases within CO2-water systems.

PubMed

Warr, Oliver; Rochelle, Christopher A; Masters, Andrew J; Ballentine, Christopher J

2016-01-01

An experimental approach is presented which can be used to determine partitioning of trace gases within CO2-water systems. The key advantages of this system are (1) The system can be isolated with no external exchange, making it ideal for experiments with conservative tracers. (2) Both phases can be sampled concurrently to give an accurate composition at each phase at any given time. (3) Use of a lower temperature flow loop outside of the reactor removes contamination and facilitates sampling. (4) Rapid equilibration at given pressure/temperature conditions is significantly aided by stirring and circulating the water phase using a magnetic stirrer and high-pressure liquid chromatography pump, respectively.

Natural selection for costly nutrient recycling in simulated microbial metacommunities.

PubMed

Boyle, Richard A; Williams, Hywel T P; Lenton, Timothy M

2012-11-07

Recycling of essential nutrients occurs at scales from microbial communities to global biogeochemical cycles, often in association with ecological interactions in which two or more species utilise each others' metabolic by-products. However, recycling loops may be unstable; sequences of reactions leading to net recycling may be parasitised by side-reactions causing nutrient loss, while some reactions in any closed recycling loop are likely to be costly to participants. Here we examine the stability of nutrient recycling loops in an individual-based ecosystem model based on microbial functional types that differ in their metabolism. A supplied nutrient is utilised by a "source" functional type, generating a secondary nutrient that is subsequently used by two other types-a "mutualist" that regenerates the initial nutrient at a growth rate cost, and a "parasite" that produces a refractory waste product but does not incur any additional cost. The three functional types are distributed across a metacommunity in which separate patches are linked by a stochastic diffusive migration process. Regions of high mutualist abundance feature high levels of nutrient recycling and increased local population density leading to greater export of individuals, allowing the source-mutualist recycling loop to spread across the system. Individual-level selection favouring parasites is balanced by patch-level selection for high productivity, indirectly favouring mutualists due to the synergistic productivity benefits of the recycling loop they support. This suggests that multi-level selection may promote nutrient cycling and thereby help to explain the apparent ubiquity and stability of nutrient recycling in nature.

Round Trip Energy Efficiency of NASA Glenn Regenerative Fuel Cell System

NASA Technical Reports Server (NTRS)

Garcia, Christopher P.; Chang, Bei-jiann; Johnson, Donald W.; Bents, David J.; Scullin, Vincent J.; Jakupca, Ian J.; Scullin, Vincent J.; Jakupca, Ian J.

2006-01-01

NASA Glenn Research Center (GRC) has recently demonstrated a Polymer Electrolyte Membrane (PEM) based hydrogen/oxygen regenerative fuel cell system (RFCS) that operated for a charge/discharge cycle with round trip efficiency (RTE) greater than 50 percent. The regenerative fuel cell system (RFCS) demonstrated closed loop energy storage over a pressure range of 90 to 190 psig. In charge mode, a constant electrical power profile of 7.1 kWe was absorbed by the RFCS and stored as pressurized hydrogen and oxygen gas. In discharge mode, the system delivered 3 to 4 kWe of electrical power along with product water. Fuel cell and electrolyzer power profiles and polarization performance are documented in this paper. Individual cell performance and the variation of cell voltages within the electrochemical stacks are also reported. Fuel cell efficiency, electrolyzer efficiency, and the system RTE were calculated from the test data and are included below.

A closed-loop air revitalization process technology demonstrator

NASA Astrophysics Data System (ADS)

Mulloth, Lila; Perry, Jay; Luna, Bernadette; Kliss, Mark

Demonstrating a sustainable, reliable life support system process design that possesses the capability to close the oxygen cycle to the greatest extent possible is required for extensive surface exploration of the Moon and Mars by humans. A conceptual closed-loop air revitalization system process technology demonstrator that combines the CO2 removal, recovery, and reduction and oxygen generation operations in a single compact envelope is described. NASA has developed, and in some cases flown, process technologies for capturing metabolic CO2 from air, reducing CO2 to H2O and CH4, electrolyzing H2O to O2, and electrolyzing CO2 to O2 and CO among a number of candidates. Traditionally, these processes either operate in parallel with one another or have not taken full benefit of a unit operation-based design approach to take complete advantage of the synergy between individual technologies. The appropriate combination of process technologies must capitalize on the advantageous aspects of individual technologies while eliminating or transforming the features that limit their feasibility when considered alone. Such a process technology integration approach also provides advantages of optimized mass, power and volume characteristics for the hardware embodiment. The conceptual air revitalization system process design is an ideal technology demonstrator for the critically needed closed-loop life support capabilities for long duration human exploration of the lunar surface and extending crewed space exploration toward Mars. The conceptual process design incorporates low power CO2 removal, process gas drying, and advanced engineered adsorbents being developed by NASA and industry.

Closed-loop Habitation Air Revitalization Model for Regenerative Life Support Systems

NASA Technical Reports Server (NTRS)

Hart, Maxwell M.

1991-01-01

The primary function of any life support system is to keep the crew alive by providing breathable air, potable water, edible food, and for disposal of waste. In a well-balanced or regenerative life support system, the various components are each using what is available and producing what is needed by other components so that there will always be enough chemicals in the form in which they are needed. Humans are not just users, but also one of the participating parts of the system. If a system could continuously recycle the original chemicals, this would make it virtually a Closed-loop Habitation (CH). Some difficulties in trying to create a miniature version of a CH are briefly discussed. In a miniature CH, a minimal structure must be provided and the difference must be made up by artificial parts such as physicochemical systems that perform the conversions that the Earth can achieve naturally. To study the interactions of these parts, a computer model was designed that simulates a miniature CH with emphasis on the air revitalization part. It is called the Closed-loop Habitation Air Revitalization Model (CHARM).

Exploring the life cycle management of industrial solid waste in the case of copper slag.

PubMed

Song, Xiaolong; Yang, Jianxin; Lu, Bin; Li, Bo

2013-06-01

Industrial solid waste has potential impacts on soil, water and air quality, as well as human health, during its whole life stages. A framework for the life cycle management of industrial solid waste, which integrates the source reduction process, is presented and applied to copper slag management. Three management scenarios of copper slag are developed: (i) production of cement after electric furnace treatment, (ii) production of cement after flotation, and (iii) source reduction before the recycling process. A life cycle assessment is carried out to estimate the environmental burdens of these three scenarios. Life cycle assessment results showed that the environmental burdens of the three scenarios are 2710.09, 2061.19 and 2145.02 Pt respectively. In consideration of the closed-loop recycling process, the environmental performance of the flotation approach excelled that of the electric furnace approach. Additionally, although flash smelting promotes the source reduction of copper slag compared with bath smelting, it did not reduce the overall environmental burdens resulting from the complete copper slag management process. Moreover, it led to the shifting of environmental burdens from ecosystem quality damage and resources depletion to human health damage. The case study shows that it is necessary to integrate the generation process into the whole life cycle of industrial solid waste, and to make an integrated assessment for quantifying the contribution of source reduction, rather than to simply follow the priority of source reduction and the hierarchy of waste management.

Induced natural convection thermal cycling device

DOEpatents

Heung, Leung Kit [Aiken, SC

2002-08-13

A device for separating gases, especially isotopes, by thermal cycling of a separation column using a pressure vessel mounted vertically and having baffled sources for cold and heat. Coils at the top are cooled with a fluid such as liquid nitrogen. Coils at the bottom are either electrical resistance coils or a tubular heat exchange. The sources are shrouded with an insulated "top hat" and simultaneously opened and closed at the outlets to cool or heat the separation column. Alternatively, the sources for cold and heat are mounted separately outside the vessel and an external loop is provided for each circuit.

A Concept for Power Cycling the Electronics of CALICE-AHCAL with the Train Structure of ILC

NASA Astrophysics Data System (ADS)

Göottlicher, Peter; The Calice-Collaboration

Particle flow algorithm calorimetry requires high granularity three-dimensional readout. The tight power requirement of 40 μW/channel is reached by enabling readout ASIC currents only during beam delivery, corresponding to a 1% duty cycle. EMI noise caused by current switching needs to be minimized by the power system and this paper presents ideas, simulations and first measurements for minimizing disturbances. A carefully design of circuits, printed circuit boards, grounding scheme and use of floating supplies allows current loops to be closed locally, stabilized voltages and minimal currents in the metal structures.

Colorado Springs dedicates zero-discharge coal plant. [Ray D. Nixon plant

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hennessy, M.; Zeien, C.T.

1980-12-01

The zero-discharge Ray D. Nixon coal-fired power plant was designed to treat and recycle effluents in a region with limited water supplies. The site purchase included groundwater rights and some diversion rights, but a properly-managed local aquifer was determined to be adequate. The closed-loop design recovers 95 percent of the water for reuse. The overall water-management system produces adequate water and treats effluents at less cost and with higher water-quality protection than alternate systems. (DCK)

Drought Contingency Planning on Fixed Army Installations.

DTIC Science & Technology

1987-04-01

U’- ’w w w w w~w u U u ~~u.~.~ kJb " " a, USA-CERL TECHNICAL REPORT N-87/14S. T~FL~U April 1987 Closed-Loop Water Conservation/ C4~ US Army Corps...These reservoirs constitute a major water management system, and are operated together to maximize benefits. As shown, relatively low levels of water ...lowered water level. Thus, valley-floor water levels lower than those of record probably indicate drought emergency or disaster. 24 Piezometric surface

Spacecraft Water Exposure Guidelines For Selected Contaminants. Volume 3

NASA Technical Reports Server (NTRS)

2008-01-01

Construction of the International Space Station (ISS)a multinational effort began in 1999. In its present configuration, the ISS is expected to carry a crew of three to six astronauts for up to 180 days (d). Because the space station is a closed and complex environment, some contamination of its internal atmosphere and water system is unavoidable. Several hundred chemical contaminants are likely to be found in the closed-loop atmosphere and recycled water of the ISS. To protect space crews from contaminants in potable and hygiene water, the National Aeronautics and Space Administration (NASA) requested that the National Research Council (NRC) provide guidance on how to develop water exposure guidelines and subsequently review NASA's development of the exposure guidelines for specific chemicals.

Exploration Life Support Critical Questions for Future Human Space Missions

NASA Technical Reports Server (NTRS)

Kwert, Michael K.; Barta, Daniel J.; McQuillan, Jeff

2010-01-01

Exploration Life Support (ELS) is a current project under NASA's Exploration Systems Mission Directorate. The ELS Project plans, coordinates and implements the development of advanced life support technologies for human exploration missions in space. Recent work has focused on closed loop atmosphere and water systems for long duration missions, including habitats and pressurized rovers. But, what are the critical questions facing life support system developers for these and other future human missions? This paper explores those questions and how progress in the development of ELS technologies can help answer them. The ELS Project includes the following Elements: Atmosphere Revitalization Systems, Water Recovery Systems, Waste Management Systems, Habitation Engineering, Systems Integration, Modeling and Analysis, and Validation and Testing, which includes the Sub-Elements Flight Experiments and Integrated Testing. Systems engineering analysis by ELS seeks to optimize overall mission architectures by considering all the internal and external interfaces of the life support system and the potential for reduction or reuse of commodities. In particular, various sources and sinks of water and oxygen are considered along with the implications on loop closure and the resulting launch mass requirements. Systems analysis will be validated through the data gathered from integrated testing, which will demonstrate the interfaces of a closed loop life support system. By applying a systematic process for defining, sorting and answering critical life support questions, the ELS project is preparing for a variety of future human space missions

Limit Cycle Bifurcations by Perturbing a Piecewise Hamiltonian System with a Double Homoclinic Loop

NASA Astrophysics Data System (ADS)

Xiong, Yanqin

2016-06-01

This paper is concerned with the bifurcation problem of limit cycles by perturbing a piecewise Hamiltonian system with a double homoclinic loop. First, the derivative of the first Melnikov function is provided. Then, we use it, together with the analytic method, to derive the asymptotic expansion of the first Melnikov function near the loop. Meanwhile, we present the first coefficients in the expansion, which can be applied to study the limit cycle bifurcation near the loop. We give sufficient conditions for this system to have 14 limit cycles in the neighborhood of the loop. As an application, a piecewise polynomial Liénard system is investigated, finding six limit cycles with the help of the obtained method.

A proof-of-principle simulation for closed-loop control based on preexisting experimental thalamic DBS-enhanced instrumental learning.

PubMed

Wang, Ching-Fu; Yang, Shih-Hung; Lin, Sheng-Huang; Chen, Po-Chuan; Lo, Yu-Chun; Pan, Han-Chi; Lai, Hsin-Yi; Liao, Lun-De; Lin, Hui-Ching; Chen, Hsu-Yan; Huang, Wei-Chen; Huang, Wun-Jhu; Chen, You-Yin

Deep brain stimulation (DBS) has been applied as an effective therapy for treating Parkinson's disease or essential tremor. Several open-loop DBS control strategies have been developed for clinical experiments, but they are limited by short battery life and inefficient therapy. Therefore, many closed-loop DBS control systems have been designed to tackle these problems by automatically adjusting the stimulation parameters via feedback from neural signals, which has been reported to reduce the power consumption. However, when the association between the biomarkers of the model and stimulation is unclear, it is difficult to develop an optimal control scheme for other DBS applications, i.e., DBS-enhanced instrumental learning. Furthermore, few studies have investigated the effect of closed-loop DBS control for cognition function, such as instrumental skill learning, and have been implemented in simulation environments. In this paper, we proposed a proof-of-principle design for a closed-loop DBS system, cognitive-enhancing DBS (ceDBS), which enhanced skill learning based on in vivo experimental data. The ceDBS acquired local field potential (LFP) signal from the thalamic central lateral (CL) nuclei of animals through a neural signal processing system. A strong coupling of the theta oscillation (4-7 Hz) and the learning period was found in the water reward-related lever-pressing learning task. Therefore, the theta-band power ratio, which was the averaged theta band to averaged total band (1-55 Hz) power ratio, could be used as a physiological marker for enhancement of instrumental skill learning. The on-line extraction of the theta-band power ratio was implemented on a field-programmable gate array (FPGA). An autoregressive with exogenous inputs (ARX)-based predictor was designed to construct a CL-thalamic DBS model and forecast the future physiological marker according to the past physiological marker and applied DBS. The prediction could further assist the design of a closed-loop DBS controller. A DBS controller based on a fuzzy expert system was devised to automatically control DBS according to the predicted physiological marker via a set of rules. The simulated experimental results demonstrate that the ceDBS based on the closed-loop control architecture not only reduced power consumption using the predictive physiological marker, but also achieved a desired level of physiological marker through the DBS controller. Copyright © 2017 Elsevier Inc. All rights reserved.

A Comparison of Supercritical Carbon Dioxide Power Cycle Configurations with an Emphasis on CSP Applications (Presentation)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Neises, T.; Turchi, C.

2013-09-01

Recent research suggests that an emerging power cycle technology using supercritical carbon dioxide (s-CO2) operated in a closed-loop Brayton cycle offers the potential of equivalent or higher cycle efficiency versus supercritical or superheated steam cycles at temperatures relevant for CSP applications. Preliminary design-point modeling suggests that s-CO2 cycle configurations can be devised that have similar overall efficiency but different temperature and/or pressure characteristics. This paper employs a more detailed heat exchanger model than previous work to compare the recompression and partial cooling cycles, two cycles with high design-point efficiencies, and illustrates the potential advantages of the latter. Integration of themore » cycles into CSP systems is studied, with a focus on sensible heat thermal storage and direct s-CO2 receivers. Results show the partial cooling cycle may offer a larger temperature difference across the primary heat exchanger, thereby potentially reducing heat exchanger cost and improving CSP receiver efficiency.« less

Coherent Structures and Evolution of Vorticity in Short-Crested Breaking Surface Waves

NASA Astrophysics Data System (ADS)

Kirby, James; Derakhti, Morteza

2017-11-01

We employ a multi-phase LES/VOF code to study turbulence and coherent structures generated during breaking of short-crested surface water waves. We examine the evolution of coherent vortex structures evolving at the scale of the width of the breaking event, and their long-time interaction with smaller vortex loops formed by the local instability of the breaking crest. Long-time results are often characterized by the detachment of the larger scale vortex loop from the surface and formation of a closed vortex ring. The evolution of circulation for the vortical flow field is examined. The initial concentration of forcing close to the free surface leads to spatial distributions of both span-wise and vertical vorticity distributions which are concentrated close to the surface. This result, which persists into shallow water, is at odds with the basic simplicity of the Peregrine mechanism, suggesting that even shallow flows such as the surf zone should be regarded as being forced (in dissipative situations) by a wave-induced surface stress rather than a uniform-over-depth body force. The localized forcing leads to the development of a complex pattern of stream-wise vorticity, comparable in strength to the vertical and span-wise components, and also persist into shallow water. NSF OCE-1435147.

Open Cascades as Simple Solutions to Providing Ultrasensitivity and Adaptation in Cellular Signaling

PubMed Central

Srividhya, Jeyaraman; Li, Yongfeng; Pomerening, Joseph R.

2011-01-01

Cell signaling is achieved predominantly by reversible phosphorylation-dephosphorylation reaction cascades. Up until now, circuits conferring adaptation have all required the presence of a cascade with some type of closed topology: negative–feedback loop with a buffering node, or incoherent feedforward loop with a proportioner node. In this paper—using Goldbeter and Koshland-type expressions—we propose a differential equation model to describe a generic, open signaling cascade that elicits an adaptation response. This is accomplished by coupling N phosphorylation–dephosphorylation cycles unidirectionally, without any explicit feedback loops. Using this model, we show that as the length of the cascade grows, the steady states of the downstream cycles reach a limiting value. In other words, our model indicates that there are a minimum number of cycles required to achieve a maximum in sensitivity and amplitude in the response of a signaling cascade. We also describe for the first time that the phenomenon of ultrasensitivity can be further subdivided into three sub–regimes, separated by sharp stimulus threshold values: OFF, OFF-ON-OFF, and ON. In the OFF-ON-OFF regime, an interesting property emerges. In the presence of a basal amount of activity, the temporal evolution of early cycles yields damped peak responses. On the other hand, the downstream cycles switch rapidly to a higher activity state for an extended period of time, prior to settling to an OFF state (OFF-ON-OFF). This response arises from the changing dynamics between a feed–forward activation module and dephosphorylation reactions. In conclusion, our model gives the new perspective that open signaling cascades embedded in complex biochemical circuits may possess the ability to show a switch–like adaptation response, without the need for any explicit feedback circuitry. PMID:21566270

Solar water-heating system for the Ingham County geriatric medical care facility, Okemos, Michigan. Operational and maintenance instruction manual

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

The objectives of the Ingham County Solar Project include: the demonstration of a major operational supplement to fossil fuels, thereby reducing the demand for non-renewable energy sources, demonstration of the economic and technical feasibility of solar systems as an important energy supplement over the expected life of the building, and to encourage Michigan industry to produce and incorporate solar systems in their own facility. The Ingham County solar system consists of approximately 10,000 square feet of solar collectors connected in a closed configuration loop. The primary loop solution is a mixture of water and propylene glycol which flows through themore » tube side of a heat exchanger connected to the primary storage tank. The heat energy which is supplied to the primary storage tank is subsequently utilized to increase the temperature of the laundry water, kitchen water, and domestic potable water.« less

Operational and maintenance instruction manual for the Ingham County Geriatric Medical Care Facility solar water-heating system

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

The Ingham County solar system consists of approximately 10,000 square feet of solar collectors connected in a closed configuration loop. The primary loop solution is a 1:12 mixture of water and propylene glycol which flows through the tube side of a heat exchanger connected to the primary storage tank. The heat energy which is supplied to the primary storage tank is subsequently used to preheat the temperature of the laundry water, kitchen water, and domestic potable water. Included in this report are: detailed drawings and flow chart; operational methodology; preventive maintenance instructions; general instructions and safety precautions; and a correctivemore » maintenance and tabulation of failure modes. Appendices include: manufacturers technical manual and component specifications; IBM data sensors and responsibilities; digital county monitor operations manual; and on site monitor operations manual. Reference CAPE-2834. (LS)« less

NEWS Climatology Project: The State of the Water Cycle at Continental to Global Scales

NASA Technical Reports Server (NTRS)

Rodell, Matthew; LEcuyer, Tristan; Beaudoing, Hiroko Kato; Olson, Bill

2011-01-01

NASA's Energy and Water Cycle Study (NEWS) program fosters collaborative research towards improved quantification and prediction of water and energy cycle consequences of climate change. In order to measure change, it is first necessary to describe current conditions. The goal of the NEWS Water and Energy Cycle Climatology project is to develop "state of the global water cycle" and "state of the global energy cycle" assessments based on data from modern ground and space based observing systems and data integrating models. The project is a multiinstitutional collaboration with more than 20 active contributors. This presentation will describe results of the first stage of the water budget analysis, whose goal was to characterize the current state of the water cycle on mean monthly, continental scales. We examine our success in closing the water budget within the expected uncertainty range and the effects of forcing budget closure as a method for refining individual flux estimates.

Human life support during interplanetary travel and domicile. III - Mars expedition system trade study

NASA Technical Reports Server (NTRS)

Seshan, P. K.; Ferrall, Joseph F.; Rohatgi, Naresh K.

1991-01-01

Several alternative configurations of life-support systems (LSSs) for a Mars missions are compared analytically on a quantitative basis in terms of weight, volume, and power. A baseline technology set is utilized for the illustrations of systems including totally open loop, carbon dioxide removal only, partially closed loop, and totally closed loop. The analytical model takes advantage of a modular, top-down hierarchical breakdown of LSS subsystems into functional elements that represent individual processing technologies. The open-loop systems are not competitive in terms of weight for both long-duration orbiters and short-duration lander vehicles, and power demands are lowest with the open loop and highest with the closed loop. The closed-loop system can reduce vehicle weight by over 70,000 lbs and thereby overcome the power penalty of 1600 W; the closed-loop variety is championed as the preferred system for a Mars expedition.

Molecular dynamics simulation study of hydrogen bonding in aqueous poly(ethylene oxide) solutions.

PubMed

Smith, G D; Bedrov, D; Borodin, O

2000-12-25

A molecular dynamics simulation study of hydrogen bonding in poly(ethylene oxide) (PEO)/water solutions was performed. PEO-water and water-water hydrogen bonding manifested complex dependence on both composition and temperature. Strong water clustering in concentrated solutions was seen. Saturation of hydrogen bonding at w(p) approximately equal to 0.5 and a dramatic decrease in PEO-water hydrogen bonding with increasing temperature, consistent with experimentally observed closed-loop phase behavior, were observed. Little tendency toward intermolecular bridging of PEO chains by water molecules was seen.

Space shuttle main engine definition (phase B). Volume 2: Avionics. [for space shuttle

NASA Technical Reports Server (NTRS)

1971-01-01

The advent of the space shuttle engine with its requirements for high specific impulse, long life, and low cost have dictated a combustion cycle and a closed loop control system to allow the engine components to run close to operating limits. These performance requirements, combined with the necessity for low operational costs, have placed new demands on rocket engine control, system checkout, and diagnosis technology. Based on considerations of precision environment, and compatibility with vehicle interface commands, an electronic control, makes available many functions that logically provide the information required for engine system checkout and diagnosis.

Decision-Assist and Closed-Loop Control of Fluid Therapy

DTIC Science & Technology

2012-03-30

achieve target endpoints while reducing fluid needs in experimental models of hemorrhage. During the previous funding cycle, along with our... IABP ) (standard of care blood pressure monitor "gold standard") in cardiac surgical patients to blood pressure recorded by the WVSM. Rational for...WVSM vs Gold standard IABP 2) History of neuropraxia 3) Refusal to consent 4) Failure to obtain radial artery cannulation Ten CPB Patients were

Electronic Warfare Closed Loop Laboratory (EWCLL) Antenna Motor Software and Hardware Development

DTIC Science & Technology

2016-09-01

ARL-TN-0779 ● SEP 2016 US Army Research Laboratory Electronic Warfare Closed Loop Laboratory (EWCLL) Antenna Motor Software and...Electronic Warfare Closed Loop Laboratory (EWCLL) Antenna Motor Software and Hardware Development by Neal Tesny Sensors and Electron Devices Directorate...TITLE AND SUBTITLE Electronic Warfare Closed Loop Laboratory (EWCLL) Antenna Motor Software and Hardware Development 5a. CONTRACT NUMBER 5b

Closed-loop spontaneous baroreflex transfer function is inappropriate for system identification of neural arc but partly accurate for peripheral arc: predictability analysis

PubMed Central

Kamiya, Atsunori; Kawada, Toru; Shimizu, Shuji; Sugimachi, Masaru

2011-01-01

Abstract Although the dynamic characteristics of the baroreflex system have been described by baroreflex transfer functions obtained from open-loop analysis, the predictability of time-series output dynamics from input signals, which should confirm the accuracy of system identification, remains to be elucidated. Moreover, despite theoretical concerns over closed-loop system identification, the accuracy and the predictability of the closed-loop spontaneous baroreflex transfer function have not been evaluated compared with the open-loop transfer function. Using urethane and α-chloralose anaesthetized, vagotomized and aortic-denervated rabbits (n = 10), we identified open-loop baroreflex transfer functions by recording renal sympathetic nerve activity (SNA) while varying the vascularly isolated intracarotid sinus pressure (CSP) according to a binary random (white-noise) sequence (operating pressure ± 20 mmHg), and using a simplified equation to calculate closed-loop-spontaneous baroreflex transfer function while matching CSP with systemic arterial pressure (AP). Our results showed that the open-loop baroreflex transfer functions for the neural and peripheral arcs predicted the time-series SNA and AP outputs from measured CSP and SNA inputs, with r2 of 0.8 ± 0.1 and 0.8 ± 0.1, respectively. In contrast, the closed-loop-spontaneous baroreflex transfer function for the neural arc was markedly different from the open-loop transfer function (enhanced gain increase and a phase lead), and did not predict the time-series SNA dynamics (r2; 0.1 ± 0.1). However, the closed-loop-spontaneous baroreflex transfer function of the peripheral arc partially matched the open-loop transfer function in gain and phase functions, and had limited but reasonable predictability of the time-series AP dynamics (r2, 0.7 ± 0.1). A numerical simulation suggested that a noise predominantly in the neural arc under resting conditions might be a possible mechanism responsible for our findings. Furthermore, the predictabilities of the neural arc transfer functions obtained in open-loop and closed-loop conditions were validated by closed-loop pharmacological (phenylephrine and nitroprusside infusions) pressure interventions. Time-series SNA responses to drug-induced AP changes predicted by the open-loop transfer function matched closely the measured responses (r2, 0.9 ± 0.1), whereas SNA responses predicted by closed-loop-spontaneous transfer function deviated greatly and were the inverse of measured responses (r, −0.8 ± 0.2). These results indicate that although the spontaneous baroreflex transfer function obtained by closed-loop analysis has been believed to represent the neural arc function, it is inappropriate for system identification of the neural arc but is essentially appropriate for the peripheral arc under resting conditions, when compared with open-loop analysis. PMID:21486839

How The Army Can Be An Environmental Paragon Through Energy

DTIC Science & Technology

2005-04-01

with recycled energy efficient material . Installing solar heating and solar energy devices on all new buildings will allow water to be heated ...ground heat exchanger , heat pump, and ductwork to deliver the air. The heat exchanger consists of pipes (a loop) buried under the ground close to a...building. Water or water plus antifreeze flows through the heat exchanger pipes absorbing heat (in the winter) and giving up heat (in the summer

Conditions for Stabilizability of Linear Switched Systems

NASA Astrophysics Data System (ADS)

Minh, Vu Trieu

2011-06-01

This paper investigates some conditions that can provide stabilizability for linear switched systems with polytopic uncertainties via their closed loop linear quadratic state feedback regulator. The closed loop switched systems can stabilize unstable open loop systems or stable open loop systems but in which there is no solution for a common Lyapunov matrix. For continuous time switched linear systems, we show that if there exists solution in an associated Riccati equation for the closed loop systems sharing one common Lyapunov matrix, the switched linear systems are stable. For the discrete time switched systems, we derive a Linear Matrix Inequality (LMI) to calculate a common Lyapunov matrix and solution for the stable closed loop feedback systems. These closed loop linear quadratic state feedback regulators guarantee the global asymptotical stability for any switched linear systems with any switching signal sequence.

Note: A dual temperature closed loop batch reactor for determining the partitioning of trace gases within CO{sub 2}-water systems

DOE Office of Scientific and Technical Information (OSTI.GOV)

Warr, Oliver, E-mail: oliver.warr@earth.ox.ac.uk; Ballentine, Christopher J.; Rochelle, Christopher A.

An experimental approach is presented which can be used to determine partitioning of trace gases within CO{sub 2}-water systems. The key advantages of this system are (1) The system can be isolated with no external exchange, making it ideal for experiments with conservative tracers. (2) Both phases can be sampled concurrently to give an accurate composition at each phase at any given time. (3) Use of a lower temperature flow loop outside of the reactor removes contamination and facilitates sampling. (4) Rapid equilibration at given pressure/temperature conditions is significantly aided by stirring and circulating the water phase using a magneticmore » stirrer and high-pressure liquid chromatography pump, respectively.« less

Pump, and earth-testable spacecraft capillary heat transport loop using augmentation pump and check valves

NASA Technical Reports Server (NTRS)

Baker, David (Inventor)

1998-01-01

A spacecraft includes heat-generating payload equipment, and a heat transport system with a cold plate thermally coupled to the equipment and a capillary-wick evaporator, for evaporating coolant liquid to cool the equipment. The coolant vapor is coupled to a condenser and in a loop back to the evaporator. A heated coolant reservoir is coupled to the loop for pressure control. If the wick is not wetted, heat transfer will not begin or continue. A pair of check valves are coupled in the loop, and the heater is cycled for augmentation pumping of coolant to and from the reservoir. This augmentation pumping, in conjunction with the check valves, wets the wick. The wick liquid storage capacity allows the augmentation pump to provide continuous pulsed liquid flow to assure continuous vapor transport and a continuously operating heat transport system. The check valves are of the ball type to assure maximum reliability. However, any type of check valve can be used, including designs which are preloaded in the closed position. The check valve may use any ball or poppet material which resists corrosion. For optimum performance during testing on Earth, the ball or poppet would have neutral buoyancy or be configured in a closed position when the heat transport system is not operating. The ball may be porous to allow passage of coolant vapor.

Portable Nanomesh Creates Safer Drinking Water

NASA Technical Reports Server (NTRS)

2008-01-01

Providing astronauts with clean water is essential to space exploration to ensure the health and well-being of crewmembers away from Earth. For the sake of efficient and safe long-term space travel, NASA constantly seeks to improve the process of filtering and re-using wastewater in closed-loop systems. Because it would be impractical for astronauts to bring months (or years) worth of water with them, reducing the weight and space taken by water storage through recycling and filtering as much water as possible is crucial. Closed-loop systems using nanotechnology allow wastewater to be cleaned and reused while keeping to a minimum the amount of drinking water carried on missions. Current high-speed filtration methods usually require electricity, and methods without electricity usually prove impractical or slow. Known for their superior strength and electrical conductivity, carbon nanotubes measure only a few nanometers in diameter; a nanometer is one billionth of a meter, or roughly one hundred-thousandth the width of a human hair. Nanotubes have improved water filtration by eliminating the need for chemical treatments, significant pressure, and heavy water tanks, which makes the new technology especially appealing for applications where small, efficient, lightweight materials are required, whether on Earth or in space. "NASA will need small volume, effective water purification systems for future long-duration space flight," said Johnson Space Center s Karen Pickering. NASA advances in water filtration with nanotechnology are now also protecting human health in the most remote areas of Earth.

Passive decay heat removal system for water-cooled nuclear reactors

DOEpatents

Forsberg, Charles W.

1991-01-01

A passive decay-heat removal system for a water-cooled nuclear reactor employs a closed heat transfer loop having heat-exchanging coils inside an open-topped, insulated box located inside the reactor vessel, below its normal water level, in communication with a condenser located outside of containment and exposed to the atmosphere. The heat transfer loop is located such that the evaporator is in a position where, when the water level drops in the reactor, it will become exposed to steam. Vapor produced in the evaporator passes upward to the condenser above the normal water level. In operation, condensation in the condenser removes heat from the system, and the condensed liquid is returned to the evaporator. The system is disposed such that during normal reactor operations where the water level is at its usual position, very little heat will be removed from the system, but during emergency, low water level conditions, substantial amounts of decay heat will be removed.

Facility for generating crew waste water product for ECLSS testing

NASA Technical Reports Server (NTRS)

Buitekant, Alan; Roberts, Barry C.

1990-01-01

An End-use Equipment Facility (EEF) has been constructed which is used to simulate water interfaces between the Space Station Freedom Environmental Control and Life Support Systems (ECLSS) and man systems. The EEF is used to generate waste water to be treated by ECLSS water recovery systems. The EEF will also be used to close the water recovery loop by allowing test subjects to use recovered hygiene and potable water during several phases of testing. This paper describes the design and basic operation of the EEF.

Determination of organic carbon and ionic accountability of various waste and product waters derived from ECLSS water recovery tests and Spacelab humidity condensate

NASA Technical Reports Server (NTRS)

Carter, Donald L.; Cole, Harold; Habercom, Mark; Griffith, Guy

1992-01-01

The development of a closed-loop water recovery system for Space Station Freedom involves many technical challenges associated with contaminant removal. Attention is presently given to the characterization of contaminants constituting total organic carbon (TOC), and to the Hubaux and Vos (1970) statistical model for low level TOC that has been employed. A tabulation is given for TOC accountability in the case of both potable and hygiene waters.

Photocatalytic post-treatment in waste water reclamation systems

NASA Technical Reports Server (NTRS)

Cooper, Gerald; Ratcliff, Matthew A.; Verostko, Charles E.

1989-01-01

A photocatalytic water purification process is described which effectively oxidizes organic impurities common to reclaimed waste waters and humidity condensates to carbon dioxide at ambient temperatures. With this process, total organic carbon concentrations below 500 ppb are readily achieved. The temperature dependence of the process is well described by the Arrhenius equation and an activation energy barrier of 3.5 Kcal/mole. The posttreatment approach for waste water reclamation described here shows potential for integration with closed-loop life support systems.

18 CFR 1304.205 - Other water-use facilities.

Code of Federal Regulations, 2014 CFR

2014-04-01

... concrete boat launching ramp with associated driveway may be located within the access corridor... concrete is allowable; asphalt is not permitted. (b) Tables or benches for cleaning fish are permitted on... adjacent structures during winter drawdown. (h) Closed loop heat exchanges for residential heat pump...

18 CFR 1304.205 - Other water-use facilities.

Code of Federal Regulations, 2013 CFR

2013-04-01

... concrete boat launching ramp with associated driveway may be located within the access corridor... concrete is allowable; asphalt is not permitted. (b) Tables or benches for cleaning fish are permitted on... adjacent structures during winter drawdown. (h) Closed loop heat exchanges for residential heat pump...

18 CFR 1304.205 - Other water-use facilities.

Code of Federal Regulations, 2012 CFR

2012-04-01

... concrete boat launching ramp with associated driveway may be located within the access corridor... concrete is allowable; asphalt is not permitted. (b) Tables or benches for cleaning fish are permitted on... adjacent structures during winter drawdown. (h) Closed loop heat exchanges for residential heat pump...

Review article: closed-loop systems in anesthesia: is there a potential for closed-loop fluid management and hemodynamic optimization?

PubMed

Rinehart, Joseph; Liu, Ngai; Alexander, Brenton; Cannesson, Maxime

2012-01-01

Closed-loop (automated) controllers are encountered in all aspects of modern life in applications ranging from air-conditioning to spaceflight. Although these systems are virtually ubiquitous, they are infrequently used in anesthesiology because of the complexity of physiologic systems and the difficulty in obtaining reliable and valid feedback data from the patient. Despite these challenges, closed-loop systems are being increasingly studied and improved for medical use. Two recent developments have made fluid administration a candidate for closed-loop control. First, the further description and development of dynamic predictors of fluid responsiveness provides a strong parameter for use as a control variable to guide fluid administration. Second, rapid advances in noninvasive monitoring of cardiac output and other hemodynamic variables make goal-directed therapy applicable for a wide range of patients in a variety of clinical care settings. In this article, we review the history of closed-loop controllers in clinical care, discuss the current understanding and limitations of the dynamic predictors of fluid responsiveness, and examine how these variables might be incorporated into a closed-loop fluid administration system.

Space life support engineering program

NASA Technical Reports Server (NTRS)

Seagrave, Richard C.

1991-01-01

This report covers the first six months of work performed under the NASA University Grant awarded to Iowa State University to perform research on two topics relating to the development of closed-loop long-term life support systems. A comprehensive study to develop software to simulate the dynamic operation of water reclamation systems in long-term closed-loop life support systems is being carried out as part of an overall program for the design of systems for a Mars voyage. This project is being done in parallel with a similar effort in the Department of Chemistry to develop durable accurate low-cost sensors for monitoring of trace chemical and biological species in recycled water supplies. Aspen-Plus software is being used on a group of high-performance workstations to develop the steady state descriptions for a number of existing technologies. Following completion, a dynamic simulation package will be developed for determining the response of such systems to changes in the metabolic needs of the crew and to upsets in system hardware performance.

Finite Feedback Cycling in Structural Equation Models

ERIC Educational Resources Information Center

Hayduk, Leslie A.

2009-01-01

In models containing reciprocal effects, or longer causal loops, the usual effect estimates assume that any effect touching a loop initiates an infinite cycling of effects around that loop. The real world, in contrast, might permit only finite feedback cycles. I use a simple hypothetical model to demonstrate that if the world permits only a few…

Comparative assessment of the efficacy of closed helical loop and T-loop for space closure in lingual orthodontics-a finite element study.

PubMed

Chacko, Ajay; Tikku, Tripti; Khanna, Rohit; Maurya, Rana Pratap; Srivastava, Kamna

2018-05-28

Retraction in lingual orthodontics has biomechanical differences when compared to labial orthodontics, which is not yet established. Thus, we have intended to compare the biomechanical characteristics of closed helical loop and T-loop on 1 mm activation with 30° of compensatory curvatures during retraction in lingual orthodontics. STb lingual brackets were indirectly bonded to maxillary typhodont model that was scanned to obtain FEM model. Closed helical loop (2 × 7 mm) and T-loop (6 × 2 × 7 mm) of 0.016″ × 0.016″ TMA wire were modeled without preactivation bends. Preactivation bends at 30° were given in the software. Boundary conditions were set. The force (F) and moment (M) of both the loops were determined on 1 mm activation, using ANSYS software. M/F ratio was also calculated for both the loops. T-loop exerted less force, thus increased M/F ratio as compared to closed helical loop on 1 mm activation. When torque has to be preserved in the anterior segment during retraction in lingual orthodontics, T-loop can be preferred over closed helical loop.

Gas Foil Bearing Misalignment and Unbalance Effects

NASA Technical Reports Server (NTRS)

Howard, Samuel A.

2008-01-01

The effects of misalignment and unbalance on gas foil bearings are presented. The future of U.S. space exploration includes plans to conduct science missions aboard space vehicles, return humans to the Moon, and place humans on Mars. All of these endeavors are of long duration, and require high amounts of electrical power for propulsion, life support, mission operations, etc. One potential source of electrical power of sufficient magnitude and duration is a nuclear-fission-based system. The system architecture would consist of a nuclear reactor heat source with the resulting thermal energy converted to electrical energy through a dynamic power conversion and heat rejection system. Various types of power conversion systems can be utilized, but the Closed Brayton Cycle (CBC) turboalternator is one of the leading candidates. In the CBC, an inert gas heated by the reactor drives a turboalternator, rejects excess heat to space through a heat exchanger, and returns to the reactor in a closed loop configuration. The use of the CBC for space power and propulsion is described in more detail in the literature (Mason, 2003). In the CBC system just described, the process fluid is a high pressure inert gas such as argon, krypton, or a helium-xenon mixture. Due to the closed loop nature of the system and the associated potential for damage to components in the system, contamination of the working fluid is intolerable. Since a potential source of contamination is the lubricant used in conventional turbomachinery bearings, Gas Foil Bearings (GFB) have high potential for the rotor support system. GFBs are compliant, hydrodynamic journal and thrust bearings that use a gas, such as the CBC working fluid, as their lubricant. Thus, GFBs eliminate the possibility of contamination due to lubricant leaks into the closed loop system. Gas foil bearings are currently used in many commercial applications, both terrestrial and aerospace. Aircraft Air Cycle Machines (ACMs) and ground-based microturbines have demonstrated histories of successful long-term operation using GFBs (Heshmat et al., 2000). Small aircraft propulsion engines, helicopter gas turbines, and high-speed electric motors are potential future applications.

Cadmium cycling in the water column of the Kuroshio-Oyashio Extension region: Insights from dissolved and particulate isotopic composition

NASA Astrophysics Data System (ADS)

Yang, Shun-Chung; Zhang, Jing; Sohrin, Yoshiki; Ho, Tung-Yuan

2018-07-01

We measured dissolved and particulate Cd isotopic composition in the water column of a meridional transect across the Kuroshio-Oyashio Extension region in a Japanese GEOTRACES cruise to investigate the relative influence of physical and biogeochemical processes on Cd cycling in the Northwestern Pacific Ocean. Located at 30-50°N along 165°E, the transect across the extension region possesses dramatic hydrographic contrast. Cold surface water and a relatively narrow and shallow thermocline characterizes the Oyashio Extension region in contrast to a relatively warm and highly stratified surface water and thermocline in the Kuroshio Extension region. The contrasting hydrographic distinction at the study site provides us with an ideal platform to investigate the spatial variations of Cd isotope fractionation systems in the ocean. Particulate samples demonstrated biologically preferential uptake of light Cd isotopes, and the fractionation effect varied dramatically in the surface water of the two regions, with relatively large fractionation factors in the Oyashio region. Based on the relationship of dissolved Cd concentrations and isotopic composition, we found that a closed system fractionation model can reasonably explain the relationship in the Kuroshio region. However, using dissolved Cd isotopic data, either a closed system or steady-state open system fractionation model may explain the relationship in the surface water of the Oyashio region. Particulate δ114/110Cd data further supports that the surface water of the Oyashio region matches a steady-state open system model more closely. Contrary to the surface water, the distribution of potential density exhibits comparable patterns with Cd elemental and isotopic composition in the thermocline and deep water in the two extension regions, showing that physical processes are the dominant forcing controlling Cd cycling in the deep waters. The results demonstrate that Cd isotope fractionation can match either a closed or open system Rayleigh fractionation model, depending on the relative contribution of physical and biogeochemical processes on its cycling.

Global water cycle amplifying at less than the Clausius-Clapeyron rate

PubMed Central

Skliris, Nikolaos; Zika, Jan D.; Nurser, George; Josey, Simon A.; Marsh, Robert

2016-01-01

A change in the cycle of water from dry to wet regions of the globe would have far reaching impact on humanity. As air warms, its capacity to hold water increases at the Clausius-Clapeyron rate (CC, approximately 7% °C−1). Surface ocean salinity observations have suggested the water cycle has amplified at close to CC following recent global warming, a result that was found to be at odds with state-of the art climate models. Here we employ a method based on water mass transformation theory for inferring changes in the water cycle from changes in three-dimensional salinity. Using full depth salinity observations we infer a water cycle amplification of 3.0 ± 1.6% °C−1 over 1950–2010. Climate models agree with observations in terms of a water cycle amplification (4.3 ± 2.0% °C−1) substantially less than CC adding confidence to projections of total water cycle change under greenhouse gas emission scenarios. PMID:27934946

Global water cycle amplifying at less than the Clausius-Clapeyron rate.

PubMed

Skliris, Nikolaos; Zika, Jan D; Nurser, George; Josey, Simon A; Marsh, Robert

2016-12-09

A change in the cycle of water from dry to wet regions of the globe would have far reaching impact on humanity. As air warms, its capacity to hold water increases at the Clausius-Clapeyron rate (CC, approximately 7% °C -1 ). Surface ocean salinity observations have suggested the water cycle has amplified at close to CC following recent global warming, a result that was found to be at odds with state-of the art climate models. Here we employ a method based on water mass transformation theory for inferring changes in the water cycle from changes in three-dimensional salinity. Using full depth salinity observations we infer a water cycle amplification of 3.0 ± 1.6% °C -1 over 1950-2010. Climate models agree with observations in terms of a water cycle amplification (4.3 ± 2.0% °C -1 ) substantially less than CC adding confidence to projections of total water cycle change under greenhouse gas emission scenarios.

Global water cycle amplifying at less than the Clausius-Clapeyron rate

NASA Astrophysics Data System (ADS)

Skliris, Nikolaos; Zika, Jan D.; Nurser, George; Josey, Simon A.; Marsh, Robert

2016-12-01

A change in the cycle of water from dry to wet regions of the globe would have far reaching impact on humanity. As air warms, its capacity to hold water increases at the Clausius-Clapeyron rate (CC, approximately 7% °C-1). Surface ocean salinity observations have suggested the water cycle has amplified at close to CC following recent global warming, a result that was found to be at odds with state-of the art climate models. Here we employ a method based on water mass transformation theory for inferring changes in the water cycle from changes in three-dimensional salinity. Using full depth salinity observations we infer a water cycle amplification of 3.0 ± 1.6% °C-1 over 1950-2010. Climate models agree with observations in terms of a water cycle amplification (4.3 ± 2.0% °C-1) substantially less than CC adding confidence to projections of total water cycle change under greenhouse gas emission scenarios.

Testing of a Neon Loop Heat Pipe for Large Area Cryocooling

NASA Technical Reports Server (NTRS)

Ku, Jentung; Robinson, Franklin Lee

2014-01-01

Cryocooling of large areas such as optics, detector arrays, and cryogenic propellant tanks is required for future NASA missions. A cryogenic loop heat pipe (CLHP) can provide a closed-loop cooling system for this purpose and has many advantages over other devices in terms of reduced mass, reduced vibration, high reliability, and long life. A neon CLHP was tested extensively in a thermal vacuum chamber using a cryopump as the heat sink to characterize its transient and steady performance and verify its ability to cool large areas or components. Tests conducted included loop cool-down from the ambient temperature, startup, power cycle, heat removal capability, loop capillary limit and recovery from a dry-out, low power operation, and long duration steady state operation. The neon CLHP demonstrated robust operation. The loop could be cooled from the ambient temperature to subcritical temperatures very effectively, and could start successfully by applying power to both the pump and evaporator without any pre-conditioning. It could adapt to changes in the pump power andor evaporator power, and reach a new steady state very quickly. The evaporator could remove heat loads between 0.25W and 4W. When the pump capillary limit was exceeded, the loop could resume its normal function by reducing the pump power. Steady state operations were demonstrated for up to 6 hours. The ability of the neon loop to cool large areas was therefore successfully verified.

Feasibility of Neurapheresis™ as a Therapy for Multidrug Resistant Gram-negative Bacterial Meningitis

PubMed Central

Ballard, Christi; Ashraf, Bilal; Ejikeme, Tiffany; Hansen, Brenda; Charalambous, Lefko; Pagadala, Promila; Sharma-Kuinkel, Batu K; Giamberardino, Charles; Hedstrom, Blake; Verbick, Laura Zitella; Mccabe, Aaron; Lad, Shivanand P; Fowler, Vance; Perfect, John R

2017-01-01

Abstract Background The World Health Organization has identified Pseudomonas, Acinetobacter and Klebsiella (PAK) as three multidrug resistant (MDR) gram-negative pathogens that pose a threat to human health. The greatest threat lies in hospitals, nursing homes, and patients with devices such as intravenous catheters and ventilators. Gram-negative bacterial meningitis (GBM) manifests when these bacteria invade the central nervous system. Due to the threat of increasing antibiotic resistance and the high mortality associated with MDR GBM, we have tested a closed-loop, extracorporeal cerebrospinal fluid (CSF) filtration system (NeurapheresisTM) for its applicability in this context. Here we demonstrate feasibility of Neurapheresis for MDR GBM and characterize system parameters for bacterial clearance. Methods PAK cultures were grown and diluted to 1 × 107 cells/mL in artificial CSF or Luria-Miller broth. Both single pass and closed loop filtration were performed with various tangential flow filtration (TFF) and dead-end filter paradigms. Samples were taken either immediately post-filter or after every full CSF volume cycle (150 mL) during a long-term closed loop experiment. Bacterial load, endotoxin and cytokines were quantified. Results In single pass tests, 5kDa and 100kDa TFF filters and 0.2µm and 0.45µm dead-end filters excluded all PAK organisms completely. The 100kDa and 5kDa TFF filters significantly reduced endotoxin concentration by >95% and >99% of baseline, respectively. The 5 kDa TFF filters produced a 2-log (>99%) reduction in cytokines (IL-1ra, IL-6, TNF, CRP, and CXCL10). In closed-loop experiments, both TFF filters demonstrated a 1–2 Log CFU (90–99%) reduction of all PAK organisms over 4 filtration cycles. Conclusion Neurapheresis shows potential to be an efficient multi-modal tool for controlling and treating MDR GBM in this in vitro model. Extending closed loop filtration over time demonstrates capability for rapid sterilization of the CSF. Future iterations may include adjunctive intrathecal drug delivery to further accelerate elimination of bacteria. Reduction of both endotoxin and cytokines by Neurapheresis may have significant implications for controlling the damaging neuro-inflammatory response during MDR GBM. Disclosures B. Hedstrom, Minnetronix, Inc.: Employee, Salary; L. Zitella Verbick, Minnetronix, Inc.: Employee, Salary; A. Mccabe, Minnetronix, Inc.: Employee, Salary; S. P. Lad, Minnetronix, Inc.: Collaborator and Scientific Advisor, Licensing agreement or royalty, Research grant and Research support; V. Fowler Jr., Pfizer, Novartis, Galderma, Novadigm, Durata, Debiopharm, Genentech, Achaogen, Affinium, Medicines Co., Cerexa, Tetraphase, Trius, MedImmune, Bayer, Theravance, Cubist, Basilea, Affinergy, Janssen, xBiotech, Contrafect: Consultant, Consulting fee; NIH, MedImmune, Cerexa/Forest/Actavis/Allergan, Pfizer, Advanced Liquid Logics, Theravance, Novartis, Cubist/Merck; Medical Biosurfaces; Locus; Affinergy; Contrafect; Karius: Grant Investigator, Grant recipient; Green Cross, Cubist, Cerexa, Durata, Theravance; Debiopharm: Consultant, Consulting fee; UpToDate: Royalties, Royalties

Closed-loop fiber optic gyroscope with homodyne detection

NASA Astrophysics Data System (ADS)

Zhu, Yong; Qin, BingKun; Chen, Shufen

1996-09-01

Interferometric fiber optic gyroscope (IFOG) has been analyzed with autocontrol theory in this paper. An open-loop IFOG system is not able to restrain the bias drift, but a closed-loop IFOG system can do it very well using negative feedback in order to suppress zero drift. The result of our theoretic analysis and computer simulation indicate that the bias drift of a closed-loop system is smaller than an open- loop one.

Bifurcation of Limit Cycles in a Near-Hamiltonian System with a Cusp of Order Two and a Saddle

NASA Astrophysics Data System (ADS)

Bakhshalizadeh, Ali; Zangeneh, Hamid R. Z.; Kazemi, Rasool

In this paper, the asymptotic expansion of first-order Melnikov function of a heteroclinic loop connecting a cusp of order two and a hyperbolic saddle for a planar near-Hamiltonian system is given. Next, we consider the limit cycle bifurcations of a hyper-elliptic Liénard system with this kind of heteroclinic loop and study the least upper bound of limit cycles bifurcated from the period annulus inside the heteroclinic loop, from the heteroclinic loop itself and the center. We find that at most three limit cycles can be bifurcated from the period annulus, also we present different distributions of bifurcated limit cycles.

Closed bioregenerative life support systems: Applicability to hot deserts

NASA Astrophysics Data System (ADS)

Polyakov, Yuriy S.; Musaev, Ibrahim; Polyakov, Sergey V.

2010-09-01

Water scarcity in hot deserts, which cover about one-fifth of the Earth's land area, along with rapid expansion of hot deserts into arable lands is one of the key global environmental problems. As hot deserts are extreme habitats characterized by the availability of solar energy with a nearly complete absence of organic life and water, space technology achievements in designing closed ecological systems may be applicable to the design of sustainable settlements in the deserts. This review discusses the key space technology findings for closed biogenerative life support systems (CBLSS), which can simultaneously produce food, water, nutrients, fertilizers, process wastes, and revitalize air, that can be applied to hot deserts. Among them are the closed cycle of water and the acceleration of the cycling times of carbon, biogenic compounds, and nutrients by adjusting the levels of light intensity, temperature, carbon dioxide, and air velocity over plant canopies. Enhanced growth of algae and duckweed at higher levels of carbon dioxide and light intensity can be important to provide complete water recycling and augment biomass production. The production of fertilizers and nutrients can be enhanced by applying the subsurface flow wetland technology and hyper-thermophilic aerobic bacteria for treating liquid and solid wastes. The mathematical models, optimization techniques, and non-invasive measuring techniques developed for CBLSS make it possible to monitor and optimize the performance of such closed ecological systems. The results of long-duration experiments performed in BIOS-3, Biosphere 2, Laboratory Biosphere, and other ground-based closed test facilities suggest that closed water cycle can be achieved in hot-desert bioregenerative systems using the pathways of evapotranspiration, condensation, and biological wastewater treatment technologies. We suggest that the state of the art in the CBLSS design along with the possibility of using direct sunlight for photosynthesis and recent advances in photovoltaic engineering can be used as a basis for building sustainable settlements producing food, water, and energy in hot deserts.

Water-soluble mercury ion sensing based on the thymine-Hg2+-thymine base pair using retroreflective Janus particle as an optical signaling probe.

PubMed

Chun, Hyeong Jin; Kim, Saemi; Han, Yong Duk; Kim, Dong Woo; Kim, Ka Ram; Kim, Hyo-Sop; Kim, Jae-Ho; Yoon, Hyun C

2018-05-01

Herein, we report an optical sensing platform for mercury ions (Hg 2+ ) in water based on the integration of Hg 2+ -mediated thymine-thymine (T-T) stabilization, a biotinylated stem-loop DNA probe, and a streptavidin-modified retroreflective Janus particle (SA-RJP). Two oligonucleotide probes, including a stem-loop DNA probe and an assistant DNA probe, were utilized. In the absence of Hg 2+ , the assistant DNA probe does not hybridize with the stem-loop probe due to their T-T mismatch, so the surface-immobilized stem-loop DNA probe remains a closed hairpin structure. In the presence of Hg 2+ , the DNA forms a double-stranded structure with the loop region via Hg 2+ -mediated T-T stabilization. This DNA hybridization induces stretching of the stem-loop DNA probe, exposing biotin. To translate these Hg 2+ -mediated structural changes in DNA probe into measurable signal, SA-RJP, an optical signaling label, is applied to recognize the exposed biotin. The number of biospecifically bound SA-RJPs is proportional to the concentration of Hg 2+ , so that the concentration of Hg 2+ can be quantitatively analyzed by counting the number of RJPs. Using the system, a highly selective and sensitive measurement of Hg 2+ was accomplished with a limit of detection of 0.027nM. Considering the simplified optical instrumentation required for retroreflection-based RJP counting, RJP-assisted Hg 2+ measurement can be accomplished in a much easier and inexpensive manner. Moreover, the detection of Hg 2+ in real drinking water samples including tap and commercial bottled water was successfully carried out. Copyright © 2018 Elsevier B.V. All rights reserved.

Low Speed and High Speed Correlation of SMART Active Flap Rotor Loads

NASA Technical Reports Server (NTRS)

Kottapalli, Sesi B. R.

2010-01-01

Measured, open loop and closed loop data from the SMART rotor test in the NASA Ames 40- by 80- Foot Wind Tunnel are compared with CAMRAD II calculations. One open loop high-speed case and four closed loop cases are considered. The closed loop cases include three high-speed cases and one low-speed case. Two of these high-speed cases include a 2 deg flap deflection at 5P case and a test maximum-airspeed case. This study follows a recent, open loop correlation effort that used a simple correction factor for the airfoil pitching moment Mach number. Compared to the earlier effort, the current open loop study considers more fundamental corrections based on advancing blade aerodynamic conditions. The airfoil tables themselves have been studied. Selected modifications to the HH-06 section flap airfoil pitching moment table are implemented. For the closed loop condition, the effect of the flap actuator is modeled by increased flap hinge stiffness. Overall, the open loop correlation is reasonable, thus confirming the basic correctness of the current semi-empirical modifications; the closed loop correlation is also reasonable considering that the current flap model is a first generation model. Detailed correlation results are given in the paper.

Application of a Loop-Type Laboratory Biofilm Reactor to the Evaluation of Biofilm for Some Metallic Materials and Polymers such as Urinary Stents and Catheters.

PubMed

Kanematsu, Hideyuki; Kudara, Hikonaru; Kanesaki, Shun; Kogo, Takeshi; Ikegai, Hajime; Ogawa, Akiko; Hirai, Nobumitsu

2016-10-11

A laboratory biofilm reactor (LBR) was modified to a new loop-type closed system in order to evaluate novel stents and catheter materials using 3D optical microscopy and Raman spectroscopy. Two metallic specimens, pure nickel and cupronickel (80% Cu-20% Ni), along with two polymers, silicone and polyurethane, were chosen as examples to ratify the system. Each set of specimens was assigned to the LBR using either tap water or an NB (Nutrient broth based on peptone from animal foods and beef extract mainly)-cultured solution with E-coli formed over 48-72 h. The specimens were then analyzed using Raman Spectroscopy. 3D optical microscopy was employed to corroborate the Raman Spectroscopy results for only the metallic specimens since the inherent roughness of the polymer specimens made such measurements difficult. The findings suggest that the closed loop-type LBR together with Raman spectroscopy analysis is a useful method for evaluating biomaterials as a potential urinary system.

TREAT Neutronics Analysis of Water-Loop Concept Accommodating LWR 9-rod Bundle

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hill, Connie M.; Woolstenhulme, Nicolas E.; Parry, James R.

Abstract. Simulation of a variety of transient conditions has been successfully achieved in the Transient Reactor Test (TREAT) facility during operation between 1959 and 1994 to support characterization and safety analysis of nuclear fuels and materials. A majority of previously conducted tests were focused on supporting sodium-cooled fast reactor (SFR) designs. Experiments evolved in complexity. Simulation of thermal-hydraulic conditions expected to be encountered by fuels and materials in a reactor environment was realized in the development of TREAT sodium loop experiment vehicles. These loops accommodated up to 7-pin fuel bundles and served to simulate more closely the reactor environment whilemore » safely delivering large quantities of energy into the test specimen. Some of the immediate TREAT restart operations will be focused on testing light water reactor (LWR) accident tolerant fuels (ATF). Similar to the sodium loop objectives, a water loop concept, developed and analyzed in the 1990’s, aimed at achieving thermal-hydraulic conditions encountered in commercial power reactors. The historic water loop concept has been analyzed in the context of a reactivity insertion accident (RIA) simulation for high burnup LWR 2-pin and 3-pin fuel bundles. Findings showed sufficient energy could be deposited into the specimens for evaluation. Similar results of experimental feasibility for the water loop concept (past and present) have recently been obtained using MCNP6.1 with ENDF/B-VII.1 nuclear data libraries. The old water loop concept required only two central TREAT core grid spaces. Preparation for future experiments has resulted in a modified water loop conceptual design designated the TREAT water environment recirculating loop (TWERL). The current TWERL design requires nine TREAT core grid spaces in order to place the water recirculating pump under the TREAT core. Due to the effectiveness of water moderation, neutronics analysis shows that removal of seven additional TREAT fuel elements to facilitate the experiment will not inhibit the ability to successfully simulate a RIA for the 2-pin or 3-pin bundle. This new water loop design leaves room for accommodating a larger fuel pin bundle than previously analyzed. The 7-pin fuel bundle in a hexagonal array with similar spacing of fuel pins in a SFR fuel assembly was considered the minimum needed for one central fuel pin to encounter the most correct thermal conditions. The 9-rod fuel bundle in a square array similar in spacing to pins in a LWR fuel assembly would be considered the LWR equivalent. MCNP analysis conducted on a preliminary LWR 9-rod bundle design shows that sufficient energy deposition into the central pin can be achieved well within range to investigate fuel and cladding performance in a simulated RIA. This is achieved by surrounding the flow channel with an additional annulus of water. Findings also show that a highly significant increase in TREAT to specimen power coupling factor (PCF) within the central pin can be achieved by surrounding the experiment with one to two rings of TREAT upgrade fuel assemblies. The experiment design holds promise for the performance evaluation of PWR fuel at extremely high burnup under similar reactor environment conditions.« less

Barriers to improving tracheostomy care in low and middle income countries: our experience of a 23 patient closed loop audit cycle.

PubMed

Sutton, Liam; Mozaffari, Mona; Mintarti, Anna; Narula, Antony; Indrasari, Sagung Rai; Lechner, Matthias

2018-05-26

There is scope for improvement in tracheostomy care in low and middle income countries. Improvement in documentation can be achieved with professional staff education and does not require a costly intervention. Availability of equipment is a hurdle to the improvement of tracheostomy care. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

In vitro and in vivo testing of glucose-responsive insulin-delivery microdevices in diabetic rats.

PubMed

Chu, Michael K L; Chen, Jian; Gordijo, Claudia R; Chiang, Simon; Ivovic, Alexander; Koulajian, Khajag; Giacca, Adria; Wu, Xiao Yu; Sun, Yu

2012-07-21

We have developed glucose-responsive implantable microdevices for closed-loop delivery of insulin and conducted in vivo testing of these devices in diabetic rats. The microdevices consist of an albumin-based bioinorganic membrane that utilizes glucose oxidase (GOx), catalase (CAT) and manganese dioxide (MnO(2)) nanoparticles to convert a change in the environmental glucose level to a pH stimulus, which regulates the volume of pH-sensitive hydrogel nanoparticles and thereby the permeability of the membrane. The membrane is integrated with microfabricated PDMS (polydimethylsiloxane) structures to form compact, stand-alone microdevices, which do not require tethering wires or tubes. During in vitro testing, the microdevices showed glucose-responsive insulin release over multiple cycles at clinically relevant glucose concentrations. In vivo, the microdevices were able to counter hyperglycemia in diabetic rats over a one-week period. The in vitro and in vivo testing results demonstrated the efficacy of closed-loop biosensing and rapid response of the 'smart' insulin delivery devices.

A Model for Developing Clinical Analytics Capacity: Closing the Loops on Outcomes to Optimize Quality.

PubMed

Eggert, Corinne; Moselle, Kenneth; Protti, Denis; Sanders, Dale

2017-01-01

Closed Loop Analytics© is receiving growing interest in healthcare as a term referring to information technology, local data and clinical analytics working together to generate evidence for improvement. The Closed Loop Analytics model consists of three loops corresponding to the decision-making levels of an organization and the associated data within each loop - Patients, Protocols, and Populations. The authors propose that each of these levels should utilize the same ecosystem of electronic health record (EHR) and enterprise data warehouse (EDW) enabled data, in a closed-loop fashion, with that data being repackaged and delivered to suit the analytic and decision support needs of each level, in support of better outcomes.

Strain actuated aeroelastic control

NASA Technical Reports Server (NTRS)

Lazarus, Kenneth B.

1992-01-01

Viewgraphs on strain actuated aeroelastic control are presented. Topics covered include: structural and aerodynamic modeling; control law design methodology; system block diagram; adaptive wing test article; bench-top experiments; bench-top disturbance rejection: open and closed loop response; bench-top disturbance rejection: state cost versus control cost; wind tunnel experiments; wind tunnel gust alleviation: open and closed loop response at 60 mph; wind tunnel gust alleviation: state cost versus control cost at 60 mph; wind tunnel command following: open and closed loop error at 60 mph; wind tunnel flutter suppression: open loop flutter speed; and wind tunnel flutter suppression: closed loop state cost curves.

Design and Calibration of the US Army Research Laboratory (ARL) Closed Loop Laboratory Radio Frequency (RF) Propagation Section

DTIC Science & Technology

2016-10-01

ARL-TR-7860 ● OCT 2016 US Army Research Laboratory Design and Calibration of the US Army Research Laboratory (ARL) Closed Loop ...ARL-TR-7860 ● OCT 2016 US Army Research Laboratory Design and Calibration of the US Army Research Laboratory (ARL) Closed Loop Laboratory...Design and Calibration of the US Army Research Laboratory (ARL) Closed Loop Laboratory Radio Frequency (RF) Propagation Section 5a. CONTRACT NUMBER

Hypoglycaemia incidence and recovery during home use of hybrid closed-loop insulin delivery in adults with type 1 diabetes.

PubMed

Ruan, Yue; Bally, Lia; Thabit, Hood; Leelarathna, Lalantha; Hartnell, Sara; Tauschmann, Martin; Wilinska, Malgorzata E; Evans, Mark L; Mader, Julia K; Kojzar, Harald; Dellweg, Sibylle; Benesch, Carsten; Arnolds, Sabine; Pieber, Thomas R; Hovorka, Roman

2018-03-25

Glucose excursion was assessed prior to and post hypoglycaemia to increase understanding of hypoglycaemia incidence and recovery during hybrid closed-loop insulin delivery. We retrospectively analysed data from 60 adults with type 1 diabetes who received, in a crossover randomized design, day-and-night hybrid closed-loop insulin delivery and insulin pump therapy, the latter with or without real-time continuous glucose monitoring. Over 4-week study periods, we identified hypoglycaemic episodes, defined as sensor glucose <3.0 mmol/L, and analysed sensor glucose relative to the onset of hypoglycaemia. We identified 377 hypoglycaemic episodes during hybrid closed-loop intervention vs 662 during control intervention (P < .001), with a predominant reduction of nocturnal hypoglycaemia. The slope of sensor glucose prior to hypoglycaemia was steeper during closed-loop intervention than during control intervention (P < .01), while insulin delivery was reduced (P < .01). During both day and night, participants recovered from hypoglycaemia faster when treated by closed-loop intervention. At 120 minutes post hypoglycaemia, sensor glucose levels were higher during closed-loop intervention compared to the control period (P < .05). In conclusion, closed-loop intervention reduces the risk of hypoglycaemia, particularly overnight, with swift recovery from hypoglycaemia leading to higher 2-hour post-hypoglycaemia glucose levels. © 2018 John Wiley & Sons Ltd.

Combining Charge Couple Devices and Rate Sensors for the Feedforward Control System of a Charge Coupled Device Tracking Loop.

PubMed

Tang, Tao; Tian, Jing; Zhong, Daijun; Fu, Chengyu

2016-06-25

A rate feed forward control-based sensor fusion is proposed to improve the closed-loop performance for a charge couple device (CCD) tracking loop. The target trajectory is recovered by combining line of sight (LOS) errors from the CCD and the angular rate from a fiber-optic gyroscope (FOG). A Kalman filter based on the Singer acceleration model utilizes the reconstructive target trajectory to estimate the target velocity. Different from classical feed forward control, additive feedback loops are inevitably added to the original control loops due to the fact some closed-loop information is used. The transfer function of the Kalman filter in the frequency domain is built for analyzing the closed loop stability. The bandwidth of the Kalman filter is the major factor affecting the control stability and close-loop performance. Both simulations and experiments are provided to demonstrate the benefits of the proposed algorithm.

A Closed-loop Brain Computer Interface to a Virtual Reality Avatar: Gait Adaptation to Visual Kinematic Perturbations

PubMed Central

Luu, Trieu Phat; He, Yongtian; Brown, Samuel; Nakagome, Sho; Contreras-Vidal, Jose L.

2016-01-01

The control of human bipedal locomotion is of great interest to the field of lower-body brain computer interfaces (BCIs) for rehabilitation of gait. While the feasibility of a closed-loop BCI system for the control of a lower body exoskeleton has been recently shown, multi-day closed-loop neural decoding of human gait in a virtual reality (BCI-VR) environment has yet to be demonstrated. In this study, we propose a real-time closed-loop BCI that decodes lower limb joint angles from scalp electroencephalography (EEG) during treadmill walking to control the walking movements of a virtual avatar. Moreover, virtual kinematic perturbations resulting in asymmetric walking gait patterns of the avatar were also introduced to investigate gait adaptation using the closed-loop BCI-VR system over a period of eight days. Our results demonstrate the feasibility of using a closed-loop BCI to learn to control a walking avatar under normal and altered visuomotor perturbations, which involved cortical adaptations. These findings have implications for the development of BCI-VR systems for gait rehabilitation after stroke and for understanding cortical plasticity induced by a closed-loop BCI system. PMID:27713915

Virtual grasping: closed-loop force control using electrotactile feedback.

PubMed

Jorgovanovic, Nikola; Dosen, Strahinja; Djozic, Damir J; Krajoski, Goran; Farina, Dario

2014-01-01

Closing the control loop by providing somatosensory feedback to the user of a prosthesis is a well-known, long standing challenge in the field of prosthetics. Various approaches have been investigated for feedback restoration, ranging from direct neural stimulation to noninvasive sensory substitution methods. Although there are many studies presenting closed-loop systems, only a few of them objectively evaluated the closed-loop performance, mostly using vibrotactile stimulation. Importantly, the conclusions about the utility of the feedback were partly contradictory. The goal of the current study was to systematically investigate the capability of human subjects to control grasping force in closed loop using electrotactile feedback. We have developed a realistic experimental setup for virtual grasping, which operated in real time, included a set of real life objects, as well as a graphical and dynamical model of the prosthesis. We have used the setup to test 10 healthy, able bodied subjects to investigate the role of training, feedback and feedforward control, robustness of the closed loop, and the ability of the human subjects to generalize the control to previously "unseen" objects. Overall, the outcomes of this study are very optimistic with regard to the benefits of feedback and reveal various, practically relevant, aspects of closed-loop control.

Using Pyrolysis and its Bioproducts to Help Close the Loop in Sustainable Life Support Systems

NASA Technical Reports Server (NTRS)

McCoy, LaShelle E.

2012-01-01

The next step in human exploration of space is beyond low Earth orbit and possibly to sites such as the Moon and Mars. Resupply of critical life support components for missions such as these are difficult or impossible. Life support processes for closing the loop of water, oxygen and carbon have to be identified .. Currently, there are many technologies proposed for terrestrial missions for waste, water, air processing and the creation of consumables. There are a variety of different approaches, but few address all of these issues simultaneously. One candidate is pyrolysis; a method where waste streams can be heated in the absence of oxygen to undergo a thermochemical conversion producing a series of bioproducts. Bioproducts like biochar made from non-edible biomass and human solid waste can possibly provide valuable benefits such as waste reduction, regolith fertilization for increased food production, and become a consumable for water processing and air revitalization systems. Syngas containing hydrogen, carbon monoxide and cbon dioxide, can be converted to methane and dimethyl ether to create propellants. Bio-oils can be utilized as a heating fuel or fed to bioreactors that utilize oil-eating microbes. Issues such as carbon sequestration and subsequent carbon balance of the closed system and identifying ideal process methods to achieve the highest quality products, whilst being energy friendly, will also be addressed.

High performance liquid chromatography column efficiency enhancement by zero dead volume recycling and practical approach using park and recycle arrangement.

PubMed

Minarik, Marek; Franc, Martin; Minarik, Milan

2018-06-15

A new instrumental approach to recycling HPLC is described. The concept is based on fast reintroduction of incremental peak sections back onto the separation column. The re-circulation is performed within a closed loop containing only the column and two synchronized switching valves. By having HPLC pump out of the cycle, the method minimizes peak broadening due to dead volume. As a result the efficiency is dramatically increased allowing for the most demanding analytical applications. In addition, a parking loop is employed for temporary storage of analytes from the middle section of the separated mixture prior to their recycling. Copyright © 2018 Elsevier B.V. All rights reserved.

Bandwidth controller for phase-locked-loop

NASA Technical Reports Server (NTRS)

Brockman, Milton H. (Inventor)

1992-01-01

A phase locked loop utilizing digital techniques to control the closed loop bandwidth of the RF carrier phase locked loop in a receiver provides high sensitivity and a wide dynamic range for signal reception. After analog to digital conversion, a digital phase locked loop bandwidth controller provides phase error detection with automatic RF carrier closed loop tracking bandwidth control to accommodate several modes of transmission.

A Methodology to Assess the Capability of Engine Designs to Meet Closed-Loop Performance and Operability Requirements

NASA Technical Reports Server (NTRS)

Zinnecker, Alicia M.; Csank, Jeffrey

2015-01-01

Designing a closed-loop controller for an engine requires balancing trade-offs between performance and operability of the system. One such trade-off is the relationship between the 95 percent response time and minimum high-pressure compressor (HPC) surge margin (SM) attained during acceleration from idle to takeoff power. Assuming a controller has been designed to meet some specification on response time and minimum HPC SM for a mid-life (nominal) engine, there is no guarantee that these limits will not be violated as the engine ages, particularly as it reaches the end of its life. A characterization for the uncertainty in this closed-loop system due to aging is proposed that defines elliptical boundaries to estimate worst-case performance levels for a given control design point. The results of this characterization can be used to identify limiting design points that bound the possible controller designs yielding transient results that do not exceed specified limits in response time or minimum HPC SM. This characterization involves performing Monte Carlo simulation of the closed-loop system with controller constructed for a set of trial design points and developing curve fits to describe the size and orientation of each ellipse; a binary search procedure is then employed that uses these fits to identify the limiting design point. The method is demonstrated through application to a generic turbofan engine model in closed-loop with a simplified controller; it is found that the limit for which each controller was designed was exceeded by less than 4.76 percent. Extension of the characterization to another trade-off, that between the maximum high-pressure turbine (HPT) entrance temperature and minimum HPC SM, showed even better results: the maximum HPT temperature was estimated within 0.76 percent. Because of the accuracy in this estimation, this suggests another limit that may be taken into consideration during design and analysis. It also demonstrates the extension of the characterization to other attributes that contribute to the performance or operability of the engine. Metrics are proposed that, together, provide information on the shape of the trade-off between response time and minimum HPC SM, and how much each varies throughout the life cycle, at the limiting design points. These metrics also facilitate comparison of the expected transient behavior for multiple engine models.

A Methodology to Assess the Capability of Engine Designs to Meet Closed-loop Performance and Operability Requirements

NASA Technical Reports Server (NTRS)

Zinnecker, Alicia M.; Csank, Jeffrey T.

2015-01-01

Designing a closed-loop controller for an engine requires balancing trade-offs between performance and operability of the system. One such trade-off is the relationship between the 95% response time and minimum high-pressure compressor (HPC) surge margin (SM) attained during acceleration from idle to takeoff power. Assuming a controller has been designed to meet some specification on response time and minimum HPC SM for a mid-life (nominal) engine, there is no guarantee that these limits will not be violated as the engine ages, particularly as it reaches the end of its life. A characterization for the uncertainty in this closed-loop system due to aging is proposed that defines elliptical boundaries to estimate worst-case performance levels for a given control design point. The results of this characterization can be used to identify limiting design points that bound the possible con- troller designs yielding transient results that do not exceed specified limits in response time or minimum HPC SM. This characterization involves performing Monte Carlo simulation of the closed-loop system with controller constructed for a set of trial design points and developing curve fits to describe the size and orientation of each ellipse; a binary search procedure is then employed that uses these fits to identify the limiting design point. The method is demonstrated through application to a generic turbofan engine model in closed- loop with a simplified controller; it is found that the limit for which each controller was designed was exceeded by less than 4.76%. Extension of the characterization to another trade-off, that between the maximum high-pressure turbine (HPT) entrance temperature and minimum HPC SM, showed even better results: the maximum HPT temperature was estimated within 0.76%. Because of the accuracy in this estimation, this suggests another limit that may be taken into consideration during design and analysis. It also demonstrates the extension of the characterization to other attributes that contribute to the performance or operability of the engine. Metrics are proposed that, together, provide information on the shape of the trade-off between response time and minimum HPC SM, and how much each varies throughout the life cycle, at the limiting design points. These metrics also facilitate comparison of the expected transient behavior for multiple engine models.

Numerical investigation on pulsating heat pipes with nitrogen or hydrogen

NASA Astrophysics Data System (ADS)

Y Han, D.; Sun, X.; Gan, Z. H.; Y Luo, R.; Pfotenhauer, J. M.; Jiao, B.

2017-12-01

With flexible structure and excellent performance, pulsating heat pipes (PHP) are regarded as a great solution to distribute cooling power for cryocoolers. The experiments on PHPs with cryogenic fluids have been carried out, indicating their efficient performances in cryogenics. There are large differences in physical properties between the fluids at room and cryogenic temperature, resulting in their different heat transfer and oscillation characteristics. Up to now, the numerical investigations on cryogenic fluids have rarely been carried out. In this paper, the model of the closed-loop PHP with multiple liquid slugs and vapor plugs is performed with nitrogen and hydrogen as working fluids, respectively. The effects of heating wall temperature on the performance of close-looped PHPs are investigated and compared with that of water PHP.

Bubble Dynamics in Polymer Solutions Undergoing Shear.

DTIC Science & Technology

1985-04-01

cavitation bubble in water has been established as the fundamental theoretical approach to understanding this phenomenon. LA_ Laser -induced...cavitation inception. 1-2 Polymer effects on cavity appearance. 2-1 Spherical laser -induced bubble dynamics. 2-2 Vapor cavity jet formation. 2-3 Bubble...distilled water. 2-6B Nonspherical bubble dynamics in dilute polymer. 3-1 Closed-loop hydraulic cavitation tunnel. 3-2 Laser system optical components. 3-3

Monitoring Digital Closed-Loop Feedback Systems

NASA Technical Reports Server (NTRS)

Katz, Richard; Kleyner, Igor

2011-01-01

A technique of monitoring digital closed-loop feedback systems has been conceived. The basic idea is to obtain information on the performances of closed-loop feedback circuits in such systems to aid in the determination of the functionality and integrity of the circuits and of performance margins. The need for this technique arises as follows: Some modern digital systems include feedback circuits that enable other circuits to perform with precision and are tolerant of changes in environment and the device s parameters. For example, in a precision timing circuit, it is desirable to make the circuit insensitive to variability as a result of the manufacture of circuit components and to the effects of temperature, voltage, radiation, and aging. However, such a design can also result in masking the indications of damaged and/or deteriorating components. The present technique incorporates test circuitry and associated engineering-telemetry circuitry into an embedded system to monitor the closed-loop feedback circuits, using spare gates that are often available in field programmable gate arrays (FPGAs). This technique enables a test engineer to determine the amount of performance margin in the system, detect out of family circuit performance, and determine one or more trend(s) in the performance of the system. In one system to which the technique has been applied, an ultra-stable oscillator is used as a reference for internal adjustment of 12 time-to-digital converters (TDCs). The feedback circuit produces a pulse-width-modulated signal that is fed as a control input into an amplifier, which controls the circuit s operating voltage. If the circuit s gates are determined to be operating too slowly or rapidly when their timing is compared with that of the reference signal, then the pulse width increases or decreases, respectively, thereby commanding the amplifier to increase or reduce, respectively, its output level, and "adjust" the speed of the circuits. The nominal frequency of the TDC s pulse width modulated outputs is approximately 40 kHz. In this system, the technique is implemented by means of a monitoring circuit that includes a 20-MHz sampling circuit and a 24-bit accumulator with a gate time of 10 ms. The monitoring circuit measures the duty cycle of each of the 12 TDCs at a repetition rate of 28 Hz. The accumulator content is reset to all zeroes at the beginning of each measurement period and is then incremented or decremented based of the value of the state of the pulse width modulated signal. Positive or negative values in the accumulator correspond to duty cycles greater or less, respectively, than 50 percent.

DEMONSTRATION OF A CLOSED LOOP REUSE SYSTEM IN A FIBERGLAS TEXTILE PLANT

EPA Science Inventory

The report describes work done toward providing a totally recycled water system for Owens-Corning's textile fiber manufacturing plant at Anderson, SC. (The work was based on pre-1968 pilot plant work by Owens-Corning that resulted in development of totally recycled industrial was...

Biological Life Support Systems

NASA Technical Reports Server (NTRS)

1997-01-01

Session MP2 includes short reports on: (1) Crew Regenerative Life Support in Long Duration Space Missions; (2) Bioconversion Systems for Food and Water on Long Term Space Missions; (3) Novel Laboratory Approaches to Multi-purpose Aquatic Biogenerative Closed-Loop Food Production Systems; and (4) Artificial Neural Network Derived Plant Growth Models.

Closed-loop carrier phase synchronization techniques motivated by likelihood functions

NASA Technical Reports Server (NTRS)

Tsou, H.; Hinedi, S.; Simon, M.

1994-01-01

This article reexamines the notion of closed-loop carrier phase synchronization motivated by the theory of maximum a posteriori phase estimation with emphasis on the development of new structures based on both maximum-likelihood and average-likelihood functions. The criterion of performance used for comparison of all the closed-loop structures discussed is the mean-squared phase error for a fixed-loop bandwidth.

A Review: Using Pyrolysis and its Bioproducts to Help Close the Loop in Sustainable Life Support Systems

NASA Technical Reports Server (NTRS)

McCoy, LaShelle E.

2013-01-01

The next step in human exploration of space is beyond low Earth orbit and possibly to sites such as the Moon and Mars. Resupply of critical life support components for missions such as these are difficult or impossible. Life support processes for closing the loop of water, oxygen and carbon have to be identified. Currently, there are many technologies proposed for terrestrial missions for waste, water, air processing. and the creation of consumables. There are a variety of different approaches, but few address all of these issues simultaneously. One candidate is pyrolysis; a method where waste streams can be heated in the absence of oxygen to undergo a thermochemical conversion producing a series of bioproducts. Bioproducts like biochar made from non-edible biomass and human solid waste can possibly provide valuable benefits such as waste reduction, regolith fertilization for increased food production, and become a consumable for water processing and air revitalization systems. Syngas containing hydrogen, carbon monoxide and carbon dioxide, can be converted to methane and dimethyl ether to create propellants. Bio-oils can be utilized as a heating fuel or fed to bioreactors that utilize oil-eating microbes.

Simplified formula for mean cycle-slip time of phase-locked loops with steady-state phase error.

NASA Technical Reports Server (NTRS)

Tausworthe, R. C.

1972-01-01

Previous work shows that the mean time from lock to a slipped cycle of a phase-locked loop is given by a certain double integral. Accurate numerical evaluation of this formula for the second-order loop is extremely vexing because the difference between exponentially large quantities is involved. The presented article demonstrates a method in which a much-reduced precision program can be used to obtain the mean first-cycle slip time for a loop of arbitrary degree tracking at a specified SNR and steady-state phase error. It also presents a simple approximate formula that is asymptotically tight at higher loop SNR.

DIRECT-CYCLE, BOILING-WATER NUCLEAR REACTOR

DOEpatents

Harrer, J.M.; Fromm, L.W. Jr.; Kolba, V.M.

1962-08-14

A direct-cycle boiling-water nuclear reactor is described that employs a closed vessel and a plurality of fuel assemblies, each comprising an outer tube closed at its lower end, an inner tube, fuel rods in the space between the tubes and within the inner tube. A body of water lying within the pressure vessel and outside the fuel assemblies is converted to saturated steam, which enters each fuel assembly at the top and is converted to superheated steam in the fuel assembly while it is passing therethrough first downward through the space between the inner and outer tubes of the fuel assembly and then upward through the inner tube. (AEC)

78 FR 19585 - Drawbridge Operation Regulations; China Basin, San Francisco, CA

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-02

... scheduled CycleSF, a community event. This deviation allows the bridge to remain in the closed-to-navigation... above Mean High Water in the closed-to-navigation position. The draw opens on signal if at least one... allow participants in the CycleSF to cross the bridge during the event. This temporary deviation has...

A comparative approach to closed-loop computation.

PubMed

Roth, E; Sponberg, S; Cowan, N J

2014-04-01

Neural computation is inescapably closed-loop: the nervous system processes sensory signals to shape motor output, and motor output consequently shapes sensory input. Technological advances have enabled neuroscientists to close, open, and alter feedback loops in a wide range of experimental preparations. The experimental capability of manipulating the topology-that is, how information can flow between subsystems-provides new opportunities to understand the mechanisms and computations underlying behavior. These experiments encompass a spectrum of approaches from fully open-loop, restrained preparations to the fully closed-loop character of free behavior. Control theory and system identification provide a clear computational framework for relating these experimental approaches. We describe recent progress and new directions for translating experiments at one level in this spectrum to predictions at another level. Operating across this spectrum can reveal new understanding of how low-level neural mechanisms relate to high-level function during closed-loop behavior. Copyright © 2013 Elsevier Ltd. All rights reserved.

Production and Field Planting of Vegetative Propagules for Restoration of Redhead Grass and Sago Pondweed in Chesapeake Bay

DTIC Science & Technology

2009-08-01

submerged aquatic vegetation (SAV) have been lost from shallow waters of Chesapeake Bay (Orth and Moore 1983) and other coastal ecosystems worldwide...a mixture of ambient estuarine water from the Choptank River (a tributary of Chesapeake Bay) and freshwater (tap) needed to maintain a salinity of 7...with a mixture of freshwater and ambient estuarine water (to maintain a salinity of 10) that was circulated through a closed- loop recirculation system

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fathi, Nima; McDaniel, Patrick; Vorobieff, Peter

The aim of this paper is evaluating the efficiency of a novel combined solar-nuclear cycle. CFD-Thermal analysis is performed to apply the available surplus heat from the nuclear cycle and measure the available kinetic energy of air for the turbine of a solar chimney power plant system (SCPPS). The presented idea helps to decrease the thermal pollution and handle the water shortage supply for water plant by replacing the cooling tower by solar chimney power plant to get the surplus heat from the available warm air in the secondary loop of the reactor. By applying this idea to a typicalmore » 1000 MW nuclear power plant with a 0.33 thermal efficiency, we can increase it to 0.39.« less

Solar Metal Sulfate-Ammonia Based Thermochemical Water Splitting Cycle for Hydrogen Production

NASA Technical Reports Server (NTRS)

T-Raissi, Ali (Inventor); Muradov, Nazim (Inventor); Huang, Cunping (Inventor)

2014-01-01

Two classes of hybrid/thermochemical water splitting processes for the production of hydrogen and oxygen have been proposed based on (1) metal sulfate-ammonia cycles (2) metal pyrosulfate-ammonia cycles. Methods and systems for a metal sulfate MSO.sub.4--NH3 cycle for producing H2 and O2 from a closed system including feeding an aqueous (NH3)(4)SO3 solution into a photoctalytic reactor to oxidize the aqueous (NH3)(4)SO3 into aqueous (NH3)(2)SO4 and reduce water to hydrogen, mixing the resulting aqueous (NH3)(2)SO4 with metal oxide (e.g. ZnO) to form a slurry, heating the slurry of aqueous (NH4)(2)SO4 and ZnO(s) in the low temperature reactor to produce a gaseous mixture of NH3 and H2O and solid ZnSO4(s), heating solid ZnSO4 at a high temperature reactor to produce a gaseous mixture of SO2 and O2 and solid product ZnO, mixing the gaseous mixture of SO2 and O2 with an NH3 and H2O stream in an absorber to form aqueous (NH4)(2)SO3 solution and separate O2 for aqueous solution, recycling the resultant solution back to the photoreactor and sending ZnO to mix with aqueous (NH4)(2)SO4 solution to close the water splitting cycle wherein gaseous H2 and O2 are the only products output from the closed ZnSO4--NH3 cycle.

A Summary of Closed Brayton Cycle Development Activities at NASA

NASA Technical Reports Server (NTRS)

Mason, Lee S.

2009-01-01

NASA has been involved in the development of Closed Brayton Cycle (CBC) power conversion technology since the 1960's. CBC systems can be coupled to reactor, isotope, or solar heat sources and offer the potential for high efficiency, long life, and scalability to high power. In the 1960's and 1970's, NASA and industry developed the 10 kW Brayton Rotating Unit (BRU) and the 2 kW mini-BRU demonstrating technical feasibility and performance, In the 1980's, a 25 kW CBC Solar Dynamic (SD) power system option was developed for Space Station Freedom and the technology was demonstrated in the 1990's as part of the 2 kW SO Ground Test Demonstration (GTD). Since the early 2000's, NASA has been pursuing CBC technology for space reactor applications. Before it was cancelled, the Jupiter Icy Moons Orbiter (HMO) mission was considering a 100 kWclass CBC system coupled to a gas-cooled fission reactor. Currently, CBC technology is being explored for Fission Surface Power (FSP) systems to provide base power on the moon and Mars. These recent activities have resulted in several CBC-related technology development projects including a 50 kW Alternator Test Unit, a 20 kW Dual Brayton Test Loop, a 2 kW Direct Drive Gas Brayton Test Loop, and a 12 kW FSP Power Conversion Unit design.

Multiday Fully Closed Loop Insulin Delivery in Monitored Outpatient Conditions

ClinicalTrials.gov

2014-04-29

To Demonstrate That the Closed Loop System Can be Used Safely Over a Few Consecutive Days.; To Assess Effectiveness in Maintaining Patients' Glucose Levels in the Target Range of 70 to 180 mg/dl, Measured by Blood Glucose Sensor.; To Evaluate the User Experience With a Closed Loop System

Closed Loop Vibrational Control: Theory and Applications

DTIC Science & Technology

1993-10-01

the open loop system dynamics will be close to that of Bit. However, in general, in a closed loop system with a specified feedback co-’ - oller , for...Juang, and G. Rodriguez , "Formulations and Applications of Large Structure Actuator and Sensor Placements," Second VPI & SU/AIAA Symposium on Dynamics

Trace organic solutes in closed-loop forward osmosis applications: influence of membrane fouling and modeling of solute build-up.

PubMed

D'Haese, Arnout; Le-Clech, Pierre; Van Nevel, Sam; Verbeken, Kim; Cornelissen, Emile R; Khan, Stuart J; Verliefde, Arne R D

2013-09-15

In this study, trace organics transport in closed-loop forward osmosis (FO) systems was assessed. The FO systems considered, consisted of an FO unit and a nanofiltration (NF) or reverse osmosis (RO) unit, with the draw solution circulating between both units. The rejection of trace organics by FO, NF and RO was tested. It was found that the rejection rates of FO were generally comparable with NF and lower than RO rejection rates. To assess the influence of fouling in FO on trace organics rejection, FO membranes were fouled with sodium alginate, bovine serum albumin or by biofilm growth, after which trace organics rejection was tested. A negative influence of fouling on FO rejection was found which was limited in most cases, while it was significant for some compounds such as paracetamol and naproxen, indicating specific compound-foulant interactions. The transport mechanism of trace organics in FO was tested, in order to differentiate between diffusive and convective transport. The concentration of trace organics in the final product water and the build-up of trace organics in the draw solution were modeled assuming the draw solution was reconcentrated by NF/RO and taking into account different transport mechanisms for the FO membrane and different rejection rates by NF/RO. Modeling results showed that if the FO rejection rate is lower than the RO rejection rate (as is the case for most compounds tested), the added value of the FO-RO cycle compared to RO only at steady-state was small for diffusively and negative for convectively transported trace organics. Modeling also showed that trace organics accumulate in the draw solution. Copyright © 2013 Elsevier Ltd. All rights reserved.

Non-Toxic, Low-Freezing, Drop-In Replacement Heat Transfer Fluids

NASA Technical Reports Server (NTRS)

Cutbirth, J. Michael

2012-01-01

A non-toxic, non-flammable, low-freezing heat transfer fluid is being developed for drop-in replacement within current and future heat transfer loops currently using water or alcohol-based coolants. Numerous water-soluble compounds were down-selected and screened for toxicological, physical, chemical, compatibility, thermodynamic, and heat transfer properties. Two fluids were developed, one with a freezing point near 0 C, and one with a suppressed freezing point. Both fluids contain an additive package to improve material compatibility and microbial resistance. The optimized sub-zero solution had a freezing point of 30 C, and a freezing volume expansion of 10-percent of water. The toxicity of the solutions was experimentally determined as LD(50) greater than 5g/kg. The solutions were found to produce minimal corrosion with materials identified by NASA as potentially existing in secondary cooling loops. Thermal/hydrodynamic performance exceeded that of glycol-based fluids with comparable freezing points for temperatures Tf greater than 20 C. The additive package was demonstrated as a buffering agent to compensate for CO2 absorption, and to prevent microbial growth. The optimized solutions were determined to have physically/chemically stable shelf lives for freeze/thaw cycles and longterm test loop tests.

Development of a Test for Evaluation of the Hydrothermal Stability of Sorbents Used in Closed-Loop CO2 Removal Systems

NASA Technical Reports Server (NTRS)

Knox, James C.; Gauto, Hernando; Miller, Lee A.

2015-01-01

The International Space Station Carbon Dioxide Removal Assembly uses zeolite 5A molecular sieve material packed into beds for the capture of cabin CO2. The beds are cyclically heated to drive off the CO2 and restore the removal capacity. Over time, the sorbent material has been found to break down resulting in dust that restricts flow through the beds. Humidity adsorbed in the 5A zeolite when it is heated is a suspected cause of this sorbent degradation. To evaluate the impact of adsorbed water during thermal cycling, the Hydrothermal Stability Test was developed. The test configuration provides comparative side-by-side flow restriction data for two sorbent materials at specifically controlled humidity levels. While the initial focus of the testing is on 5A zeolite materials currently used on the ISS, the system will also be used to evaluate future candidate materials. This paper describes the approach, the test system, current results, and future testing.

Development status of regenerable solid amine CO2 control systems

NASA Technical Reports Server (NTRS)

Colling, A. K., Jr.; Nalette, T. A.; Cusick, R. J.; Reysa, R. P.

1985-01-01

The development history of solid amine/water desorbed (SAWD) CO2 control systems is reviewed. The design of the preprototype SAWD I CO2 system on the basis of a three-man metabolic load at the 3.8 mm Hg ambient CO2 level, and the functions of the CO2 removal, CO2 storage/delivery, controller, and life test laboratory support packages are described. The development of a full-scale multiple canister SAWD II preprototype system, which is capable of conducting the CO2 removal/concentration function in a closed-loop atmosphere revitalization system during zero-gravity operation, is examined. The operation of the SAWD II system, including the absorption and desorption cycles, is analyzed. A reduction in the thermal mass of the canister and the system's energy transfer technique result in efficient energy use. The polyether foam, nylon felt, nickel foam, spring retained, and metal bellows bed tests performed to determine the design of the zero-gravity canister are studied; metal bellows are selected for the canister's configuration.

Crystal structure of a polyhistidine-tagged recombinant catalytic subunit of cAMP-dependent protein kinase complexed with the peptide inhibitor PKI(5-24) and adenosine.

PubMed

Narayana, N; Cox, S; Shaltiel, S; Taylor, S S; Xuong, N

1997-04-15

The crystal structure of the hexahistidine-tagged mouse recombinant catalytic subunit (H6-rC) of cAMP-dependent protein kinase (cAPK), complexed with a 20-residue peptide inhibitor from the heat-stable protein kinase inhibitor PKI(5-24) and adenosine, was determined at 2.2 A resolution. Novel crystallization conditions were required to grow the ternary complex crystals. The structure was refined to a final crystallographic R-factor of 18.2% with good stereochemical parameters. The "active" enzyme adopts a "closed" conformation as found in rC:PKI(5-24) [Knighton et al. (1991a,b) Science 253, 407-414, 414-420] and packs in a similar manner with the peptide providing a major contact surface. This structure clearly defines the subsites of the unique nucleotide binding site found in the protein kinase family. The adenosine occupies a mostly hydrophobic pocket at the base of the cleft between the two lobes and is completely buried. The missing triphosphate moiety of ATP is filled with a water molecule (Wtr 415) which replaces the gamma-phosphate of ATP. The glycine-rich loop between beta1 and beta2 helps to anchor the phosphates while the ribose ring is buried beneath beta-strand 2. Another ordered water molecule (Wtr 375) is pentacoordinated with polar atoms from adenosine, Leu 49 in beta-strand 1, Glu 127 in the linker strand between the two lobes, Tyr 330, and a third water molecule, Wtr 359. The conserved nucleotide fold can be defined as a lid comprised of beta-strand 1, the glycine-rich loop, and beta-strand 2. The adenine ring is buried beneath beta-strand 1 and the linker strand (120-127) that joins the small and large lobes. The C-terminal tail containing Tyr 330, a segment that lies outside the conserved core, covers this fold and anchors it in a closed conformation. The main-chain atoms of the flexible glycine-rich loop (residues 50-55) in the ATP binding domain have a mean B-factor of 41.4 A2. This loop is quite mobile, in striking contrast to the other conserved loops that converge at the active site cleft. The catalytic loop (residues 166-171) and the Mg2+ positioning loop (residues 184-186) are a stable part of the large lobe and have low B-factors in all structures solved to date. The stability of the glycine-rich loop is highly dependent on the ligands that occupy the active site cleft with maximum stability achieved in the ternary complex containing Mg x ATP and the peptide inhibitor. In this ternary complex the gamma-phosphate is secured between both lobes by hydrogen bonds to the backbone amide of Ser 53 in the glycine-rich loop and the amino group of Lys 168 in the catalytic loop. In the adenosine ternary complex the water molecule replacing the gamma-phosphate hydrogen bonds between Lys 168 and Asp 166 and makes no contact with the small lobe. This glycine-rich loop is thus the most mobile component of the active site cleft, with the tip of the loop being highly sensitive to what occupies the gamma-subsite.

Brayton-cycle heat exchanger technology program

NASA Technical Reports Server (NTRS)

Killackey, J. J.; Coombs, M. G.; Graves, R. F.; Morse, C. J.

1976-01-01

The following five tasks designed to advance this development of heat exchanger systems for close loop Brayton cycle power systems are presented: (1) heat transfer and pressure drop data for a finned tubular heat transfer matrix. The tubes are arranged in a triangular array with copper stainless steel laminate strips helically wound on the tubes to form a disk fin geometry; (2) the development of a modularized waste heat exchanger. Means to provide verified double containment are described; (3) the design, fabrication, and test of compact plate fin heat exchangers representative of full scale Brayton cycle recuperators; (4) the analysis and design of bellows suitable for operation at 1600 F and 200 psia for 1,000 cycles and 50,000 hours creep life; and (5) screening tests used to select a low cost braze alloy with the desirable attributes of a gold base alloy. A total of 22 different alloys were investigated; the final selection was Nicrobraz 30.

Closed-loop thrust and pressure profile throttling of a nitrous oxide/hydroxyl-terminated polybutadiene hybrid rocket motor

NASA Astrophysics Data System (ADS)

Peterson, Zachary W.

Hybrid motors that employ non-toxic, non-explosive components with a liquid oxidizer and a solid hydrocarbon fuel grain have inherently safe operating characteristics. The inherent safety of hybrid rocket motors offers the potential to greatly reduce overall operating costs. Another key advantage of hybrid rocket motors is the potential for in-flight shutdown, restart, and throttle by controlling the pressure drop between the oxidizer tank and the injector. This research designed, developed, and ground tested a closed-loop throttle controller for a hybrid rocket motor using nitrous oxide and hydroxyl-terminated polybutadiene as propellants. The research simultaneously developed closed-loop throttle algorithms and lab scale motor hardware to evaluate the fidelity of the throttle simulations and algorithms. Initial open-loop motor tests were performed to better classify system parameters and to validate motor performance values. Deep-throttle open-loop tests evaluated limits of stable thrust that can be achieved on the test hardware. Open-loop tests demonstrated the ability to throttle the motor to less than 10% of maximum thrust with little reduction in effective specific impulse and acoustical stability. Following the open-loop development, closed-loop, hardware-in-the-loop tests were performed. The closed-loop controller successfully tracked prescribed step and ramp command profiles with a high degree of fidelity. Steady-state accuracy was greatly improved over uncontrolled thrust.

Kasza: design of a closed water system for the greenhouse horticulture.

PubMed

van der Velde, Raphaël T; Voogt, Wim; Pickhardt, Pieter W

2008-01-01

The need for a closed and sustainable water system in greenhouse areas is stimulated by the implementation in the Netherlands of the European Framework Directive. The Dutch national project Kasza: Design of a Closed Water System for the Greenhouse Horticulture will provide information how the water system in a greenhouse horticulture area can be closed. In this paper the conceptual design of two systems to close the water cycle in a greenhouse area is described. The first system with reverse osmosis system can be used in areas where desalination is required in order to be able to use the recycle water for irrigation of all crops. The second system with advanced oxidation using UV and peroxide can be applied in areas with more salt tolerant crops and good (low sodium) water sources for irrigation. Both systems are financially feasible in new greenhouse areas with substantial available recycle water. (c) IWA Publishing 2008.

INTESTINAL OBSTRUCTION

PubMed Central

Whipple, G. H.; Stone, H. B.; Bernheim, B. M.

1913-01-01

Closed duodenal loops may be made in dogs by ligatures placed just below the pancreatic duct and just beyond the duodenojejunal junction, together with a posterior gastro-enterostomy. These closed duodenal loop dogs die with symptoms like those of patients suffering from volvulus or high intestinal obstruction. This duodenal loop may simulate closely a volvulus in which there has been no vascular disturbance. Dogs with closed duodenal loops which have been washed out carefully survive a little longer on the average than animals with unwashed loops. The duration of life in the first instance is one to three days, with an average of about forty-eight hours. The dogs usually lose considerable fluid by vomiting and diarrhea. A weak pulse, low blood pressure and temperature are usually conspicuous in the last stages. Autopsy shows more or less splanchnic congestion which may be most marked in the mucosa of the upper small intestine. The peritoneum is usually clear and the closed loop may be distended with thin fluid, or collapsed, and contain only a small amount of pasty brown material. The mucosa of the loop may show ulceration and even perforation, but in the majority of cases it is intact and exhibits only a moderate congestion. Simple intestinal obstruction added to a closed duodenal loop does not modify the result in any manner, but it may hasten the fatal outcome. The liver plays no essential role as a protective agent against this poison, for a dog with an Eck fistula may live three days with a closed loop. A normal dog reacts to intraportal injection and to intravenous injection of the toxic substance in an identical manner. Drainage of this loop under certain conditions may not interfere with the general health over a period of weeks or months. Excision of the part of the duodenum included in this loop causes no disturbance. The material from the closed duodenal loops contains no bile, pancreatic juice, gastric juice, or split products from the food. It can be formed in no other way than by the activity of the intestinal mucosa and the growth of the intestinal bacteria. This material after dilution, autolysis, sterilization, and filtration produces a characteristic effect when introduced intravenously. When in toxic doses it causes a profound drop in blood pressure, general collapse, drop in temperature, salivation, vomiting, and profuse diarrhea, which is often blood-stained. Splanchnic congestion is the conspicuous feature at autopsy and shows especially in the villi of the duodenal and jejunal mucosæ. Adrenalin, during this period of low blood pressure and splanchnic congestion, will cause the usual reaction when given intravenously, but applied locally or given intravenously it causes no bleaching of the engorged intestinal mucosa. Secretin is not found in the duodenal loop fluid, and the loop material does not influence the pancreatic secretion. Intraportal injection of the toxic material gives a reaction similar to intravenous injection. Intraperitoneal and subcutaneous injections produce a relatively slow reaction which closely resembles the picture seen in the closed duodenal loop dog. In both cases there is a relatively slow absorption, but the splanchnic congestion and other findings, though less intense, are present in both groups. There seems, therefore, to be no escape from the conclusion that a poisonous substance is formed in this closed duodenal loop which is absorbed from it and causes intoxication and death. Injection of this toxic substance into a normal dog gives intoxication and a reaction more intense but similar to that developing in a closed-loop dog. PMID:19867644

78 FR 58535 - Hydropower Regulatory Efficiency Act of 2013; Supplemental Notice of Workshop

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-24

... license for hydropower development at non-powered dams and closed-loop pumped storage projects in... for licensing hydropower development at non-powered dams and closed-loop pumped storage projects... closed- loop pumped storage) affect the steps included in a two-year process? 3.9 Should there be a...

Results on reuse of reclaimed shower water

NASA Technical Reports Server (NTRS)

Verostko, Charles E.; Garcia, Rafael; Pierson, Duane L.; Reysa, Richard P.; Irbe, Robert

1986-01-01

The Waste Water Recovery System that has been used in conjunction with a microgravity whole body shower to test a closed loop shower water reclamation system applicable to the NASA Space Station employs a Thermoelectric Integrated Hollow Fiber Membrane Evaporation Subsystem. Attention is given to the suitability of a Space Shuttle soap for such crew showers, the effects of shower water on the entire system, and the purification qualities of the recovered water. The chemical pretreatment of the shower water for microorganism control involved activated carbon, mixed ion exchange resin beds, and iodine bactericide dispensing units. The water was recycled five times, demonstrating the feasibility of reuse.

The Effects of Closed-Loop Medical Devices on the Autonomy and Accountability of Persons and Systems.

PubMed

Kellmeyer, Philipp; Cochrane, Thomas; Müller, Oliver; Mitchell, Christine; Ball, Tonio; Fins, Joseph J; Biller-Andorno, Nikola

2016-10-01

Closed-loop medical devices such as brain-computer interfaces are an emerging and rapidly advancing neurotechnology. The target patients for brain-computer interfaces (BCIs) are often severely paralyzed, and thus particularly vulnerable in terms of personal autonomy, decisionmaking capacity, and agency. Here we analyze the effects of closed-loop medical devices on the autonomy and accountability of both persons (as patients or research participants) and neurotechnological closed-loop medical systems. We show that although BCIs can strengthen patient autonomy by preserving or restoring communicative abilities and/or motor control, closed-loop devices may also create challenges for moral and legal accountability. We advocate the development of a comprehensive ethical and legal framework to address the challenges of emerging closed-loop neurotechnologies like BCIs and stress the centrality of informed consent and refusal as a means to foster accountability. We propose the creation of an international neuroethics task force with members from medical neuroscience, neuroengineering, computer science, medical law, and medical ethics, as well as representatives of patient advocacy groups and the public.

75 FR 16576 - Credit for Renewable Electricity Production, Refined Coal Production, and Indian Coal Production...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-01

..., open-loop biomass, geothermal energy, solar energy, small irrigation power, municipal solid waste... electricity produced from closed-loop biomass, open-loop biomass, geothermal energy, solar energy, small... electricity produced from the qualified energy resources of wind, closed-loop biomass, geothermal energy, and...

77 FR 21835 - Credit for Renewable Electricity Production, Refined Coal Production, and Indian Coal Production...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-11

..., open-loop biomass, geothermal energy, solar energy, small irrigation power, municipal solid waste... electricity produced from closed-loop biomass, open-loop biomass, geothermal energy, solar energy, small... electricity produced from the qualified energy resources of wind, closed-loop biomass, geothermal energy, and...

76 FR 21947 - Credit for Renewable Electricity Production, Refined Coal Production, and Indian Coal Production...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-19

..., open-loop biomass, geothermal energy, solar energy, small irrigation power, municipal solid waste... electricity produced from closed-loop biomass, open-loop biomass, geothermal energy, solar energy, small... electricity produced from the qualified energy resources of wind, closed-loop biomass, geothermal energy, and...

Loop-bed combustion apparatus

DOEpatents

Shang, Jer-Yu; Mei, Joseph S.; Slagle, Frank D.; Notestein, John E.

1984-01-01

The present invention is directed to a combustion apparatus in the configuration of a oblong annulus defining a closed loop. Particulate coal together with a sulfur sorbent such as sulfur or dolomite is introduced into the closed loop, ignited, and propelled at a high rate of speed around the loop. Flue gas is withdrawn from a location in the closed loop in close proximity to an area in the loop where centrifugal force imposed upon the larger particulate material maintains these particulates at a location spaced from the flue gas outlet. Only flue gas and smaller particulates resulting from the combustion and innerparticle grinding are discharged from the combustor. This structural arrangement provides increased combustion efficiency due to the essentially complete combustion of the coal particulates as well as increased sulfur absorption due to the innerparticle grinding of the sorbent which provides greater particle surface area.

CLOSED-LOOP TREATMENT OF ELECTROLYTIC AND ELECTROLESS NICKEL RINSE WATER BY POINT-OF-USE ION EXCHANGE: A CASE STUDY

EPA Science Inventory

Many recent pilot tests have demonstrated the benefits and cost effectiveness of point-of-use treatment technologies as opposed to centralized wastewater treatment for all sizes of plating facilities. A 9-month case study at a small plating facility in Cincinnati, OH utilizing po...

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gerard, R.; Malekian, C.; Meessen, O.

The Leak Before Break (LBB) concept allows to eliminate from the design basis the double-ended guillotine break of the primary loop piping, provided it can be demonstrated by a fracture mechanics analysis that a through-wall flaw, of a size giving rise to a leakage still well detectable by the plant leak detection systems, remains stable even under accident conditions (including the Safe Shutdown Earthquake (SSE)). This concept was successfully applied to the primary loop piping of several Belgian Pressurized Water Reactor (PWR) units, operated by the Utility Electrabel. One of the main benefits is to permit justification of supports inmore » the primary loop and justification of the integrity of the reactor pressure vessel and internals in case of a Loss Of Coolant Accident (LOCA) in stretch-out conditions. For two of the Belgian PWR units, the LBB approach also made it possible to reduce the number of large hydraulic snubbers installed on the primary coolant pumps. Last but not least, the LBB concept also facilitates the steam generator replacement operations, by eliminating the need for some pipe whip restraints located close to the steam generator. In addition to the U.S. regulatory requirements, the Belgian safety authorities impose additional requirements which are described in details in a separate paper. An novel aspect of the studies performed in Belgium is the way in which residual loads in the primary loop are taken into account. Such loads may result from displacements imposed to close the primary loop in a steam generator replacement operation, especially when it is performed using the {open_quote}two cuts{close_quotes} technique. The influence of such residual loads on the LBB margins is discussed in details and typical results are presented.« less

Preliminary demonstration of a robust controller design method

NASA Technical Reports Server (NTRS)

Anderson, L. R.

1980-01-01

Alternative computational procedures for obtaining a feedback control law which yields a control signal based on measurable quantitites are evaluated. The three methods evaluated are: (1) the standard linear quadratic regulator design model; (2) minimization of the norm of the feedback matrix, k via nonlinear programming subject to the constraint that the closed loop eigenvalues be in a specified domain in the complex plane; and (3) maximize the angles between the closed loop eigenvectors in combination with minimizing the norm of K also via the constrained nonlinear programming. The third or robust design method was chosen to yield a closed loop system whose eigenvalues are insensitive to small changes in the A and B matrices. The relationship between orthogonality of closed loop eigenvectors and the sensitivity of closed loop eigenvalues is described. Computer programs are described.

Automated hybrid closed-loop control with a proportional-integral-derivative based system in adolescents and adults with type 1 diabetes: individualizing settings for optimal performance.

PubMed

Ly, Trang T; Weinzimer, Stuart A; Maahs, David M; Sherr, Jennifer L; Roy, Anirban; Grosman, Benyamin; Cantwell, Martin; Kurtz, Natalie; Carria, Lori; Messer, Laurel; von Eyben, Rie; Buckingham, Bruce A

2017-08-01

Automated insulin delivery systems, utilizing a control algorithm to dose insulin based upon subcutaneous continuous glucose sensor values and insulin pump therapy, will soon be available for commercial use. The objective of this study was to determine the preliminary safety and efficacy of initialization parameters with the Medtronic hybrid closed-loop controller by comparing percentage of time in range, 70-180 mg/dL (3.9-10 mmol/L), mean glucose values, as well as percentage of time above and below target range between sensor-augmented pump therapy and hybrid closed-loop, in adults and adolescents with type 1 diabetes. We studied an initial cohort of 9 adults followed by a second cohort of 15 adolescents, using the Medtronic hybrid closed-loop system with the proportional-integral-derivative with insulin feed-back (PID-IFB) algorithm. Hybrid closed-loop was tested in supervised hotel-based studies over 4-5 days. The overall mean percentage of time in range (70-180 mg/dL, 3.9-10 mmol/L) during hybrid closed-loop was 71.8% in the adult cohort and 69.8% in the adolescent cohort. The overall percentage of time spent under 70 mg/dL (3.9 mmol/L) was 2.0% in the adult cohort and 2.5% in the adolescent cohort. Mean glucose values were 152 mg/dL (8.4 mmol/L) in the adult cohort and 153 mg/dL (8.5 mmol/L) in the adolescent cohort. Closed-loop control using the Medtronic hybrid closed-loop system enables adaptive, real-time basal rate modulation. Initializing hybrid closed-loop in clinical practice will involve individualizing initiation parameters to optimize overall glucose control. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Direct-contact closed-loop heat exchanger

DOEpatents

Berry, Gregory F.; Minkov, Vladimir; Petrick, Michael

1984-01-01

A high temperature heat exchanger with a closed loop and a heat transfer liquid within the loop, the closed loop having a first horizontal channel with inlet and outlet means for providing direct contact of a first fluid at a first temperature with the heat transfer liquid, a second horizontal channel with inlet and outlet means for providing direct contact of a second fluid at a second temperature with the heat transfer liquid, and means for circulating the heat transfer liquid.

MELiSSA Pilot Plant: A facility for ground demonstration of a closed life support system

NASA Astrophysics Data System (ADS)

Godia, Francesc; Fossen, Arnaud; Peiro, Enrique; Gerbi, Olivier; Dussap, Gilles; Leys, Natalie; Arnau, Carolina; Milian, Ernest

MELiSSA (Micro Ecological Life Support System Alternative) is an international collaborative effort focused on the development of a Life Support System for long-term Space missions. The goals of the MELiSSA loop are the recovery of food, water and oxygen from wastes, i.e. CO2 and organic wastes, using light as a source of energy. It is conceived as a series of compartments, each one performing a specific function within this cycle, inspired in the terrestrial ecological systems. Each one of the compartments is colonized with specific bacteria or higher plants depending on its dedicated function. Therefore, its design and operational conditions should guarantee that only a given specific biological activity takes place in each compartment. Moreover, this has to be done in a controlled manner, both at the subsystems level (i.e., compartments) and at the overall system level (i.e., complete loop). In order to achieve the complete operation of such a Closed Ecological System, in a first step each compartment has to be developed at individual level, and its operation demonstrated under its associated control law. In a second step, the complete loop needs to be integrated by the connection of the different compartments in the gas, loop and solid phases. An extensive demonstration of MELiSSA loop under terrestrial conditions is a mandatory step in the process of its adaptation to space. This is the main goal of the MPP. The demonstration scenario for the MPP is the respiration equivalent of a human being, and production of 20 percent of the diet of one person. To serve this goal, the different compartments of the MELiSSA loop have been designed and sized at the pilot scale level, and further characterized. Nowadays, the focus of the MELiSSA Pilot Plant is on the integration of its compartments. To this end, the integration challenge is concentrated in three compartments devoted to the following functions: nitrification (Compartment 3, an axenic co-culture of Nitrosomonas europaea and Nitrobacter winogradskyi), edible biomass and oxygen production (Compartment 4a, an axenic co-culture of Arthrospira platensis) and oxygen consumers (Compartment 5, rats isolator). The presentation will focus on all the necessary elements to achieve this integration, particularly in the start-up of continuous operation of the bioreactors and on the key challenges addressed in the integration of the gas phase of two compartments, 4a and 5, one producing O2 and one consuming it. The design of the integration conditions to ensure the functionality of all the elements will also be discussed. Keywords:, MELiSSA, Pilot Plant, Integration, Arthrospira platensis, Nitrosomonas europaea, Nitrobacter winogradskyi

Closed-Loop Control of Complex Networks: A Trade-Off between Time and Energy

NASA Astrophysics Data System (ADS)

Sun, Yong-Zheng; Leng, Si-Yang; Lai, Ying-Cheng; Grebogi, Celso; Lin, Wei

2017-11-01

Controlling complex nonlinear networks is largely an unsolved problem at the present. Existing works focus either on open-loop control strategies and their energy consumptions or on closed-loop control schemes with an infinite-time duration. We articulate a finite-time, closed-loop controller with an eye toward the physical and mathematical underpinnings of the trade-off between the control time and energy as well as their dependence on the network parameters and structure. The closed-loop controller is tested on a large number of real systems including stem cell differentiation, food webs, random ecosystems, and spiking neuronal networks. Our results represent a step forward in developing a rigorous and general framework to control nonlinear dynamical networks with a complex topology.

DC servomechanism parameter identification: a Closed Loop Input Error approach.

PubMed

Garrido, Ruben; Miranda, Roger

2012-01-01

This paper presents a Closed Loop Input Error (CLIE) approach for on-line parametric estimation of a continuous-time model of a DC servomechanism functioning in closed loop. A standard Proportional Derivative (PD) position controller stabilizes the loop without requiring knowledge on the servomechanism parameters. The analysis of the identification algorithm takes into account the control law employed for closing the loop. The model contains four parameters that depend on the servo inertia, viscous, and Coulomb friction as well as on a constant disturbance. Lyapunov stability theory permits assessing boundedness of the signals associated to the identification algorithm. Experiments on a laboratory prototype allows evaluating the performance of the approach. Copyright © 2011 ISA. Published by Elsevier Ltd. All rights reserved.

Dislocation dynamics simulations of interactions between gliding dislocations and radiation induced prismatic loops in zirconium

NASA Astrophysics Data System (ADS)

Drouet, Julie; Dupuy, Laurent; Onimus, Fabien; Mompiou, Frédéric; Perusin, Simon; Ambard, Antoine

2014-06-01

The mechanical behavior of Pressurized Water Reactor fuel cladding tubes made of zirconium alloys is strongly affected by neutron irradiation due to the high density of radiation induced dislocation loops. In order to investigate the interaction mechanisms between gliding dislocations and loops in zirconium, a new nodal dislocation dynamics code, adapted to Hexagonal Close Packed metals, has been used. Various configurations have been systematically computed considering different glide planes, basal or prismatic, and different characters, edge or screw, for gliding dislocations with -type Burgers vectors. Simulations show various interaction mechanisms such as (i) absorption of a loop on an edge dislocation leading to the formation of a double super-jog, (ii) creation of a helical turn, on a screw dislocation, that acts as a strong pinning point or (iii) sweeping of a loop by a gliding dislocation. It is shown that the clearing of loops is more favorable when the dislocation glides in the basal plane than in the prismatic plane explaining the easy dislocation channeling in the basal plane observed after neutron irradiation by transmission electron microscopy.

Application of a Loop-Type Laboratory Biofilm Reactor to the Evaluation of Biofilm for Some Metallic Materials and Polymers such as Urinary Stents and Catheters

PubMed Central

Kanematsu, Hideyuki; Kudara, Hikonaru; Kanesaki, Shun; Kogo, Takeshi; Ikegai, Hajime; Ogawa, Akiko; Hirai, Nobumitsu

2016-01-01

A laboratory biofilm reactor (LBR) was modified to a new loop-type closed system in order to evaluate novel stents and catheter materials using 3D optical microscopy and Raman spectroscopy. Two metallic specimens, pure nickel and cupronickel (80% Cu-20% Ni), along with two polymers, silicone and polyurethane, were chosen as examples to ratify the system. Each set of specimens was assigned to the LBR using either tap water or an NB (Nutrient broth based on peptone from animal foods and beef extract mainly)—cultured solution with E-coli formed over 48–72 h. The specimens were then analyzed using Raman Spectroscopy. 3D optical microscopy was employed to corroborate the Raman Spectroscopy results for only the metallic specimens since the inherent roughness of the polymer specimens made such measurements difficult. The findings suggest that the closed loop-type LBR together with Raman spectroscopy analysis is a useful method for evaluating biomaterials as a potential urinary system. PMID:28773945

Energy Conversion Advanced Heat Transport Loop and Power Cycle

DOE Office of Scientific and Technical Information (OSTI.GOV)

Oh, C. H.

2006-08-01

The Department of Energy and the Idaho National Laboratory are developing a Next Generation Nuclear Plant (NGNP) to serve as a demonstration of state-of-the-art nuclear technology. The purpose of the demonstration is two fold 1) efficient low cost energy generation and 2) hydrogen production. Although a next generation plant could be developed as a single-purpose facility, early designs are expected to be dual-purpose. While hydrogen production and advanced energy cycles are still in its early stages of development, research towards coupling a high temperature reactor, electrical generation and hydrogen production is under way. Many aspects of the NGNP must bemore » researched and developed in order to make recommendations on the final design of the plant. Parameters such as working conditions, cycle components, working fluids, and power conversion unit configurations must be understood. Three configurations of the power conversion unit were demonstrated in this study. A three-shaft design with 3 turbines and 4 compressors, a combined cycle with a Brayton top cycle and a Rankine bottoming cycle, and a reheated cycle with 3 stages of reheat were investigated. An intermediate heat transport loop for transporting process heat to a High Temperature Steam Electrolysis (HTSE) hydrogen production plant was used. Helium, CO2, and an 80% nitrogen, 20% helium mixture (by weight) were studied to determine the best working fluid in terms cycle efficiency and development cost. In each of these configurations the relative component size were estimated for the different working fluids. The relative size of the turbomachinery was measured by comparing the power input/output of the component. For heat exchangers the volume was computed and compared. Parametric studies away from the baseline values of the three-shaft and combined cycles were performed to determine the effect of varying conditions in the cycle. This gives some insight into the sensitivity of these cycles to various operating conditions as well as trade offs between efficiency and capital cost. Prametric studies were carried out on reactor outlet temperature, mass flow, pressure, and turbine cooling. Recommendations on the optimal working fluid for each configuration were made. A steady state model comparison was made with a Closed Brayton Cycle (CBC) power conversion system developed at Sandia National Laboratory (SNL). A preliminary model of the CBC was developed in HYSYS for comparison. Temperature and pressure ratio curves for the Capstone turbine and compressor developed at SNL were implemented into the HYSYS model. A comparison between the HYSYS model and SNL loop demonstrated power output predicted by HYSYS was much larger than that in the experiment. This was due to a lack of a model for the electrical alternator which was used to measure the power from the SNL loop. Further comparisons of the HYSYS model and the CBC data are recommended. Engineering analyses were performed for several configurations of the intermediate heat transport loop that transfers heat from the nuclear reactor to the hydrogen production plant. The analyses evaluated parallel and concentric piping arrangements and two different working fluids, including helium and a liquid salt. The thermal-hydraulic analyses determined the size and insulation requirements for the hot and cold leg pipes in the different configurations. Economic analyses were performed to estimate the cost of the va« less

Full-scale 3-D finite element modeling of a two-loop pressurized water reactor for heat transfer, thermal–mechanical cyclic stress analysis, and environmental fatigue life estimation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mohanty, Subhasish; Soppet, William K.; Majumdar, Saurindranath

This paper discusses a system-level finite element model of a two-loop pressurized water reactor (PWR). Based on this model, system-level heat transfer analysis and subsequent sequentially coupled thermal-mechanical stress analysis were performed for typical thermal-mechanical fatigue cycles. The in-air fatigue lives of example components, such as the hot and cold legs, were estimated on the basis of stress analysis results, ASME in-air fatigue life estimation criteria, and fatigue design curves. Furthermore, environmental correction factors and associated PWR environment fatigue lives for the hot and cold legs were estimated by using estimated stress and strain histories and the approach described inmore » US-NRC report: NUREG-6909.« less

Water cycles in closed ecological systems: effects of atmospheric pressure.

PubMed

Rygalov, Vadim Y; Fowler, Philip A; Metz, Joannah M; Wheeler, Raymond M; Bucklin, Ray A

2002-01-01

In bioregenerative life support systems that use plants to generate food and oxygen, the largest mass flux between the plants and their surrounding environment will be water. This water cycle is a consequence of the continuous change of state (evaporation-condensation) from liquid to gas through the process of transpiration and the need to transfer heat (cool) and dehumidify the plant growth chamber. Evapotranspiration rates for full plant canopies can range from ~1 to 10 L m-2 d-1 (~1 to 10 mm m-2 d-1), with the rates depending primarily on the vapor pressure deficit (VPD) between the leaves and the air inside the plant growth chamber. VPD in turn is dependent on the air temperature, leaf temperature, and current value of relative humidity (RH). Concepts for developing closed plant growth systems, such as greenhouses for Mars, have been discussed for many years and the feasibility of such systems will depend on the overall system costs and reliability. One approach for reducing system costs would be to reduce the operating pressure within the greenhouse to reduce structural mass and gas leakage. But managing plant growth environments at low pressures (e.g., controlling humidity and heat exchange) may be difficult, and the effects of low-pressure environments on plant growth and system water cycling need further study. We present experimental evidence to show that water saturation pressures in air under isothermal conditions are only slightly affected by total pressure, but the overall water flux from evaporating surfaces can increase as pressure decreases. Mathematical models describing these observations are presented, along with discussion of the importance for considering "water cycles" in closed bioregenerative life support systems.

Water cycles in closed ecological systems: effects of atmospheric pressure

NASA Technical Reports Server (NTRS)

Rygalov, Vadim Y.; Fowler, Philip A.; Metz, Joannah M.; Wheeler, Raymond M.; Bucklin, Ray A.; Sager, J. C. (Principal Investigator)

2002-01-01

In bioregenerative life support systems that use plants to generate food and oxygen, the largest mass flux between the plants and their surrounding environment will be water. This water cycle is a consequence of the continuous change of state (evaporation-condensation) from liquid to gas through the process of transpiration and the need to transfer heat (cool) and dehumidify the plant growth chamber. Evapotranspiration rates for full plant canopies can range from 1 to 10 L m-2 d-1 (1 to 10 mm m-2 d-1), with the rates depending primarily on the vapor pressure deficit (VPD) between the leaves and the air inside the plant growth chamber. VPD in turn is dependent on the air temperature, leaf temperature, and current value of relative humidity (RH). Concepts for developing closed plant growth systems, such as greenhouses for Mars, have been discussed for many years and the feasibility of such systems will depend on the overall system costs and reliability. One approach for reducing system costs would be to reduce the operating pressure within the greenhouse to reduce structural mass and gas leakage. But managing plant growth environments at low pressures (e.g., controlling humidity and heat exchange) may be difficult, and the effects of low-pressure environments on plant growth and system water cycling need further study. We present experimental evidence to show that water saturation pressures in air under isothermal conditions are only slightly affected by total pressure, but the overall water flux from evaporating surfaces can increase as pressure decreases. Mathematical models describing these observations are presented, along with discussion of the importance for considering "water cycles" in closed bioregenerative life support systems.

Experimental study on heat transfer to supercritical water flowing through tubes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhao, M.; Gu, H.; Cheng, X.

2012-07-01

A test facility named SWAMUP (Supercritical Water Multi-Purpose Loop) has been constructed in Shanghai Jiao Tong Univ. to investigate heat transfer and pressure drop through tubes and rod bundles. SWAMUP is a closed loop with operating pressure up to 30 MPa, outlet-water temperature up to 550 deg. C, and mass flow rate up to 5 t/h. In this paper, experimental study has been carried out on heat transfer of supercritical water flowing vertically through tubes (ID=7.6 and 10 mm). A large number of test points in tubes has been obtained with a wide range of heat flux (200-1500 kw/m{sup 2})more » and mass flux (450-2000 kg/m{sup 2}s). Test results showed that heat transfer deterioration (HTD) caused by buoyancy effect only appears in upward flow and HTD caused by acceleration effect appears both in upward flow and downward flow. The heat transfer coefficients (HTC) produced in tube tests were compared with existing heat transfer correlations. (authors)« less

Closing the Feedback Loop Is Not Enough: The Assessment Spiral

ERIC Educational Resources Information Center

Wehlburg, Catherine M.

2007-01-01

For quite some time, the call to close the feedback loop has been heard throughout higher education. Faculty and administrators have paid attention, and now they can more easily than ever point to the fact that at their institution, the feedback loop is almost always closed. As reviewers from accreditation teams visit campuses, they often hear…

78 FR 62322 - Hydropower Regulatory Efficiency Act of 2013; Notice of Rescheduled Two-Year Licensing Process...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-16

... at non-powered dams and closed-loop pumped storage projects in compliance with section 6 of the... process for licensing hydropower development at non-powered dams and closed-loop pumped storage projects...-powered dam versus closed- loop pumped storage) affect the steps included in a two-year process? 3.9...

Conceptualization and validation of an open-source closed-loop deep brain stimulation system in rat.

PubMed

Wu, Hemmings; Ghekiere, Hartwin; Beeckmans, Dorien; Tambuyzer, Tim; van Kuyck, Kris; Aerts, Jean-Marie; Nuttin, Bart

2015-04-21

Conventional deep brain stimulation (DBS) applies constant electrical stimulation to specific brain regions to treat neurological disorders. Closed-loop DBS with real-time feedback is gaining attention in recent years, after proved more effective than conventional DBS in terms of pathological symptom control clinically. Here we demonstrate the conceptualization and validation of a closed-loop DBS system using open-source hardware. We used hippocampal theta oscillations as system input, and electrical stimulation in the mesencephalic reticular formation (mRt) as controller output. It is well documented that hippocampal theta oscillations are highly related to locomotion, while electrical stimulation in the mRt induces freezing. We used an Arduino open-source microcontroller between input and output sources. This allowed us to use hippocampal local field potentials (LFPs) to steer electrical stimulation in the mRt. Our results showed that closed-loop DBS significantly suppressed locomotion compared to no stimulation, and required on average only 56% of the stimulation used in open-loop DBS to reach similar effects. The main advantages of open-source hardware include wide selection and availability, high customizability, and affordability. Our open-source closed-loop DBS system is effective, and warrants further research using open-source hardware for closed-loop neuromodulation.

Conceptualization and validation of an open-source closed-loop deep brain stimulation system in rat

PubMed Central

Wu, Hemmings; Ghekiere, Hartwin; Beeckmans, Dorien; Tambuyzer, Tim; van Kuyck, Kris; Aerts, Jean-Marie; Nuttin, Bart

2015-01-01

Conventional deep brain stimulation (DBS) applies constant electrical stimulation to specific brain regions to treat neurological disorders. Closed-loop DBS with real-time feedback is gaining attention in recent years, after proved more effective than conventional DBS in terms of pathological symptom control clinically. Here we demonstrate the conceptualization and validation of a closed-loop DBS system using open-source hardware. We used hippocampal theta oscillations as system input, and electrical stimulation in the mesencephalic reticular formation (mRt) as controller output. It is well documented that hippocampal theta oscillations are highly related to locomotion, while electrical stimulation in the mRt induces freezing. We used an Arduino open-source microcontroller between input and output sources. This allowed us to use hippocampal local field potentials (LFPs) to steer electrical stimulation in the mRt. Our results showed that closed-loop DBS significantly suppressed locomotion compared to no stimulation, and required on average only 56% of the stimulation used in open-loop DBS to reach similar effects. The main advantages of open-source hardware include wide selection and availability, high customizability, and affordability. Our open-source closed-loop DBS system is effective, and warrants further research using open-source hardware for closed-loop neuromodulation. PMID:25897892

Performance constraints and compensation for teleoperation with delay

NASA Technical Reports Server (NTRS)

Mclaughlin, J. S.; Staunton, B. D.

1989-01-01

A classical control perspective is used to characterize performance constraints and evaluate compensation techniques for teleoperation with delay. Use of control concepts such as open and closed loop performance, stability, and bandwidth yield insight to the delay problem. Teleoperator performance constraints are viewed as an open loop time delay lag and as a delay-induced closed loop bandwidth constraint. These constraints are illustrated with a simple analytical tracking example which is corroborated by a real time, 'man-in-the-loop' tracking experiment. The experiment also provides insight to those controller characteristics which are unique to a human operator. Predictive displays and feedforward commands are shown to provide open loop compensation for delay lag. Low pass filtering of telemetry or feedback signals is interpreted as closed loop compensation used to maintain a sufficiently low bandwidth for stability. A new closed loop compensation approach is proposed that uses a reactive (or force feedback) hand controller to restrict system bandwidth by impeding operator inputs.

Overnight closed-loop insulin delivery with model predictive control: assessment of hypoglycemia and hyperglycemia risk using simulation studies.

PubMed

Wilinska, Malgorzata E; Budiman, Erwin S; Taub, Marc B; Elleri, Daniela; Allen, Janet M; Acerini, Carlo L; Dunger, David B; Hovorka, Roman

2009-09-01

Hypoglycemia and hyperglycemia during closed-loop insulin delivery based on subcutaneous (SC) glucose sensing may arise due to (1) overdosing and underdosing of insulin by control algorithm and (2) difference between plasma glucose (PG) and sensor glucose, which may be transient (kinetics origin and sensor artifacts) or persistent (calibration error [CE]). Using in silico testing, we assessed hypoglycemia and hyperglycemia incidence during over-night closed loop. Additionally, a comparison was made against incidence observed experimentally during open-loop single-night in-clinic studies in young people with type 1 diabetes mellitus (T1DM) treated by continuous SC insulin infusion. Simulation environment comprising 18 virtual subjects with T1DM was used to simulate overnight closed-loop study with a model predictive control (MPC) algorithm. A 15 h experiment started at 17:00 and ended at 08:00 the next day. Closed loop commenced at 21:00 and continued for 11 h. At 18:00, protocol included meal (50 g carbohydrates) accompanied by prandial insulin. The MPC algorithm advised on insulin infusion every 15 min. Sensor glucose was obtained by combining model-calculated noise-free interstitial glucose with experimentally derived transient and persistent sensor artifacts associated with FreeStyle Navigator (FSN). Transient artifacts were obtained from FSN sensor pairs worn by 58 subjects with T1DM over 194 nighttime periods. Persistent difference due to FSN CE was quantified from 585 FSN sensor insertions, yielding 1421 calibration sessions from 248 subjects with diabetes. Episodes of severe (PG < or = 36 mg/dl) and significant (PG < or = 45 mg/dl) hypoglycemia and significant hyperglycemia (PG > or = 300 mg/dl) were extracted from 18,000 simulated closed-loop nights. Severe hypoglycemia was not observed when FSN CE was less than 45%. Hypoglycemia and hyperglycemia incidence during open loop was assessed from 21 overnight studies in 17 young subjects with T1DM (8 males; 13.5 +/- 3.6 years of age; body mass index 21.0 +/- 4.0 kg/m2; duration diabetes 6.4 +/- 4.1 years; hemoglobin A1c 8.5% +/- 1.8%; mean +/- standard deviation) participating in the Artificial Pancreas Project at Cambridge. Severe and significant hypoglycemia during simulated closed loop occurred 0.75 and 17.11 times per 100 person years compared to 1739 and 3479 times per 100 person years during experimental open loop, respectively. Significant hyperglycemia during closed loop and open loop occurred 75 and 15,654 times per 100 person years, respectively. The incidence of severe and significant hypoglycemia reduced 2300- and 200-fold, respectively, during stimulated overnight closed loop with MPC compared to that observed during open-loop overnight clinical studies in young subjects with T1DM. Hyperglycemia was 200 times less likely. Overnight closed loop with the FSN and the MPC algorithm is expected to reduce substantially the risk of hypoglycemia and hyperglycemia. 2009 Diabetes Technology Society.

Fundamental Physics and Practical Applications of Electromagnetic Local Flow Control in High Speed Flows (Rutgers)

DTIC Science & Technology

2010-02-16

field. Techniques utilizing this design use an open- loop control and no flow monitoring sensors are required. Conversely, reactive (or closed - loop ...and closed (dashed line) configuration. 38 closed configuration described above, the ambiguity in the critical limits of the transition...flow; a new vortex is then shed from the cavity leading edge, closing the feedback loop .[31] Open cavities with an L/D approximately greater than

Direct-contact closed-loop heat exchanger

DOEpatents

Berry, G.F.; Minkov, V.; Petrick, M.

1981-11-02

A high temperature heat exchanger is disclosed which has a closed loop and a heat transfer liquid within the loop, the closed loop having a first horizontal channel with inlet and outlet means for providing direct contact of a first fluid at a first temperature with the heat transfer liquid, a second horizontal channel with inlet and outlet means for providing direct contact of a second fluid at a second temperature with the heat transfer liquid, and means for circulating the heat transfer liquid.

Intraoperative stroke volume optimization using stroke volume, arterial pressure, and heart rate: closed-loop (learning intravenous resuscitator) versus anesthesiologists.

PubMed

Rinehart, Joseph; Chung, Elena; Canales, Cecilia; Cannesson, Maxime

2012-10-01

The authors compared the performance of a group of anesthesia providers to closed-loop (Learning Intravenous Resuscitator [LIR]) management in a simulated hemorrhage scenario using cardiac output monitoring. A prospective cohort study. In silico simulation. University hospital anesthesiologists and the LIR closed-loop fluid administration system. Using a patient simulator, a 90-minute simulated hemorrhage protocol was run, which included a 1,200-mL blood loss over 30 minutes. Twenty practicing anesthesiology providers were asked to manage this scenario by providing fluids and vasopressor medication at their discretion. The simulation program was also run 20 times with the LIR closed-loop algorithm managing fluids and an additional 20 times with no intervention. Simulated patient weight, height, heart rate, mean arterial pressure, and cardiac output (CO) were similar at baseline. The mean stroke volume, the mean arterial pressure, CO, and the final CO were higher in the closed-loop group than in the practitioners group, and the coefficient of variance was lower. The closed-loop group received slightly more fluid (2.1 v 1.9 L, p < 0.05) than the anesthesiologist group. Despite the roughly similar volumes of fluid given, the closed-loop maintained more stable hemodynamics than the practitioners primarily because the fluid was given earlier in the protocol and CO optimized before the hemorrhage began, whereas practitioners tended to resuscitate well but only after significant hemodynamic change indicated the need. Overall, these data support the potential usefulness of this closed-loop algorithm in clinical settings in which dynamic predictors are not available or applicable. Published by Elsevier Inc.

Assessing performance of closed-loop insulin delivery systems by continuous glucose monitoring: drawbacks and way forward.

PubMed

Hovorka, Roman; Nodale, Marianna; Haidar, Ahmad; Wilinska, Malgorzata E

2013-01-01

We investigated whether continuous glucose monitoring (CGM) levels can accurately assess glycemic control while directing closed-loop insulin delivery. Data were analyzed retrospectively from 33 subjects with type 1 diabetes who underwent closed-loop and conventional pump therapy on two separate nights. Glycemic control was evaluated by reference plasma glucose and contrasted against three methods based on Navigator (Abbott Diabetes Care, Alameda, CA) CGM levels. Glucose mean and variability were estimated by unmodified CGM levels with acceptable clinical accuracy. Time when glucose was in target range was overestimated by CGM during closed-loop nights (CGM vs. plasma glucose median [interquartile range], 86% [65-97%] vs. 75% [59-91%]; P=0.04) but not during conventional pump therapy (57% [32-72%] vs. 51% [29-68%]; P=0.82) providing comparable treatment effect (mean [SD], 28% [29%] vs. 23% [21%]; P=0.11). Using the CGM measurement error of 15% derived from plasma glucose-CGM pairs (n=4,254), stochastic interpretation of CGM gave unbiased estimate of time in target during both closed-loop (79% [62-86%] vs. 75% [59-91%]; P=0.24) and conventional pump therapy (54% [33-66%] vs. 51% [29-68%]; P=0.44). Treatment effect (23% [24%] vs. 23% [21%]; P=0.96) and time below target were accurately estimated by stochastic CGM. Recalibrating CGM using reference plasma glucose values taken at the start and end of overnight closed-loop was not superior to stochastic CGM. CGM is acceptable to estimate glucose mean and variability, but without adjustment it may overestimate benefit of closed-loop. Stochastic CGM provided unbiased estimate of time when glucose is in target and below target and may be acceptable for assessment of closed-loop in the outpatient setting.

Comparison of cardiac output optimization with an automated closed-loop goal-directed fluid therapy versus non standardized manual fluid administration during elective abdominal surgery: first prospective randomized controlled trial.

PubMed

Lilot, Marc; Bellon, Amandine; Gueugnon, Marine; Laplace, Marie-Christine; Baffeleuf, Bruno; Hacquard, Pauline; Barthomeuf, Felicie; Parent, Camille; Tran, Thomas; Soubirou, Jean-Luc; Robinson, Philip; Bouvet, Lionel; Vassal, Olivia; Lehot, Jean-Jacques; Piriou, Vincent

2018-01-27

An intraoperative automated closed-loop system for goal-directed fluid therapy has been successfully tested in silico, in vivo and in a clinical case-control matching. This trial compared intraoperative cardiac output (CO) in patients managed with this closed-loop system versus usual practice in an academic medical center. The closed-loop system was connected to a CO monitoring system and delivered automated colloid fluid boluses. Moderate to high-risk abdominal surgical patients were randomized either to the closed-loop or the manual group. Intraoperative final CO was the primary endpoint. Secondary endpoints were intraoperative overall mean cardiac index (CI), increase from initial to final CI, intraoperative fluid volume and postoperative outcomes. From January 2014 to November 2015, 46 patients were randomized. There was a lower initial CI (2.06 vs. 2.51 l min -1 m -2 , p = 0.042) in the closed-loop compared to the control group. No difference in final CO and in overall mean intraoperative CI was observed between groups. A significant relative increase from initial to final CI values was observed in the closed-loop but not the control group (+ 28.6%, p = 0.006 vs. + 1.2%, p = 0.843). No difference was found for intraoperative fluid management and postoperative outcomes between groups. There was no significant impact on the primary study endpoint, but this was found in a context of unexpected lower initial CI in the closed-loop group.Trial registry number ID-RCB/EudraCT: 2013-A00770-45. ClinicalTrials.gov Identifier NCT01950845, date of registration: 17 September 2013.

Dynamic simulation of perturbation responses in a closed-loop virtual arm model.

PubMed

Du, Yu-Fan; He, Xin; Lan, Ning

2010-01-01

A closed-loop virtual arm (VA) model has been developed in SIMULINK environment by adding spinal reflex circuits and propriospinal neural networks to the open-loop VA model developed in early study [1]. An improved virtual muscle model (VM4.0) is used to speed up simulation and to generate more precise recruitment of muscle force at low levels of muscle activation. Time delays in the reflex loops are determined by their synaptic connections and afferent transmission back to the spinal cord. Reflex gains are properly selected so that closed-loop responses are stable. With the closed-loop VA model, we are developing an approach to evaluate system behaviors by dynamic simulation of perturbation responses. Joint stiffness is calculated based on simulated perturbation responses by a least-squares algorithm in MATLAB. This method of dynamic simulation will be essential for further evaluation of feedforward and reflex control of arm movement and position.

Perception as a closed-loop convergence process.

PubMed

Ahissar, Ehud; Assa, Eldad

2016-05-09

Perception of external objects involves sensory acquisition via the relevant sensory organs. A widely-accepted assumption is that the sensory organ is the first station in a serial chain of processing circuits leading to an internal circuit in which a percept emerges. This open-loop scheme, in which the interaction between the sensory organ and the environment is not affected by its concurrent downstream neuronal processing, is strongly challenged by behavioral and anatomical data. We present here a hypothesis in which the perception of external objects is a closed-loop dynamical process encompassing loops that integrate the organism and its environment and converging towards organism-environment steady-states. We discuss the consistency of closed-loop perception (CLP) with empirical data and show that it can be synthesized in a robotic setup. Testable predictions are proposed for empirical distinction between open and closed loop schemes of perception.

Perception as a closed-loop convergence process

PubMed Central

Ahissar, Ehud; Assa, Eldad

2016-01-01

Perception of external objects involves sensory acquisition via the relevant sensory organs. A widely-accepted assumption is that the sensory organ is the first station in a serial chain of processing circuits leading to an internal circuit in which a percept emerges. This open-loop scheme, in which the interaction between the sensory organ and the environment is not affected by its concurrent downstream neuronal processing, is strongly challenged by behavioral and anatomical data. We present here a hypothesis in which the perception of external objects is a closed-loop dynamical process encompassing loops that integrate the organism and its environment and converging towards organism-environment steady-states. We discuss the consistency of closed-loop perception (CLP) with empirical data and show that it can be synthesized in a robotic setup. Testable predictions are proposed for empirical distinction between open and closed loop schemes of perception. DOI: http://dx.doi.org/10.7554/eLife.12830.001 PMID:27159238

Open-Loop HIRF Experiments Performed on a Fault Tolerant Flight Control Computer

NASA Technical Reports Server (NTRS)

Koppen, Daniel M.

1997-01-01

During the third quarter of 1996, the Closed-Loop Systems Laboratory was established at the NASA Langley Research Center (LaRC) to study the effects of High Intensity Radiated Fields on complex avionic systems and control system components. This new facility provided a link and expanded upon the existing capabilities of the High Intensity Radiated Fields Laboratory at LaRC that were constructed and certified during 1995-96. The scope of the Closed-Loop Systems Laboratory is to place highly integrated avionics instrumentation into a high intensity radiated field environment, interface the avionics to a real-time flight simulation that incorporates aircraft dynamics, engines, sensors, actuators and atmospheric turbulence, and collect, analyze, and model aircraft performance. This paper describes the layout and functionality of the Closed-Loop Systems Laboratory, and the open-loop calibration experiments that led up to the commencement of closed-loop real-time flight experiments.

Competition and quality in health care markets: a differential-game approach.

PubMed

Brekke, Kurt R; Cellini, Roberto; Siciliani, Luigi; Straume, Odd Rune

2010-07-01

We investigate the effect of competition on quality in health care markets with regulated prices taking a differential game approach, in which quality is a stock variable. Using a Hotelling framework, we derive the open-loop solution (health care providers set the optimal investment plan at the initial period) and the feedback closed-loop solution (providers move investments in response to the dynamics of the states). Under the closed-loop solution competition is more intense in the sense that providers observe quality in each period and base their investment on this information. If the marginal provision cost is constant, the open-loop and closed-loop solutions coincide, and the results are similar to the ones obtained by static models. If the marginal provision cost is increasing, investment and quality are lower in the closed-loop solution (when competition is more intense). In this case, static models tend to exaggerate the positive effect of competition on quality.

The NEWS Water Cycle Climatology

NASA Astrophysics Data System (ADS)

Rodell, M.; Beaudoing, H. K.; L'Ecuyer, T.; Olson, W. S.

2012-12-01

NASA's Energy and Water Cycle Study (NEWS) program fosters collaborative research towards improved quantification and prediction of water and energy cycle consequences of climate change. In order to measure change, it is first necessary to describe current conditions. The goal of the first phase of the NEWS Water and Energy Cycle Climatology project was to develop "state of the global water cycle" and "state of the global energy cycle" assessments based on data from modern ground and space based observing systems and data integrating models. The project was a multi-institutional collaboration with more than 20 active contributors. This presentation will describe the results of the water cycle component of the first phase of the project, which include seasonal (monthly) climatologies of water fluxes over land, ocean, and atmosphere at continental and ocean basin scales. The requirement of closure of the water budget (i.e., mass conservation) at various scales was exploited to constrain the flux estimates via an optimization approach that will also be described. Further, error assessments were included with the input datasets, and we examine these in relation to inferred uncertainty in the optimized flux estimates in order to gauge our current ability to close the water budget within an expected uncertainty range.

The NEWS Water Cycle Climatology

NASA Technical Reports Server (NTRS)

Rodell, Matthew; Beaudoing, Hiroko Kato; L'Ecuyer, Tristan; William, Olson

2012-01-01

NASA's Energy and Water Cycle Study (NEWS) program fosters collaborative research towards improved quantification and prediction of water and energy cycle consequences of climate change. In order to measure change, it is first necessary to describe current conditions. The goal of the first phase of the NEWS Water and Energy Cycle Climatology project was to develop "state of the global water cycle" and "state of the global energy cycle" assessments based on data from modern ground and space based observing systems and data integrating models. The project was a multi-institutional collaboration with more than 20 active contributors. This presentation will describe the results of the water cycle component of the first phase of the project, which include seasonal (monthly) climatologies of water fluxes over land, ocean, and atmosphere at continental and ocean basin scales. The requirement of closure of the water budget (i.e., mass conservation) at various scales was exploited to constrain the flux estimates via an optimization approach that will also be described. Further, error assessments were included with the input datasets, and we examine these in relation to inferred uncertainty in the optimized flux estimates in order to gauge our current ability to close the water budget within an expected uncertainty range.

Probing the closed-loop model of mRNA translation in living cells

PubMed Central

Archer, Stuart K; Shirokikh, Nikolay E; Hallwirth, Claus V; Beilharz, Traude H; Preiss, Thomas

2015-01-01

The mRNA closed-loop, formed through interactions between the cap structure, poly(A) tail, eIF4E, eIF4G and PAB, features centrally in models of eukaryotic translation initiation, although direct support for its existence in vivo is not well established. Here, we investigated the closed-loop using a combination of mRNP isolation from rapidly cross-linked cells and high-throughput qPCR. Using the interaction between these factors and the opposing ends of mRNAs as a proxy for the closed-loop, we provide evidence that it is prevalent for eIF4E/4G-bound but unexpectedly sparse for PAB1-bound mRNAs, suggesting it primarily occurs during a distinct phase of polysome assembly. We observed mRNA-specific variation in the extent of closed-loop formation, consistent with a role for polysome topology in the control of gene expression. PMID:25826658

A Highly Efficient Six-Stroke Internal Combustion Engine Cycle with Water Injection for In-Cylinder Exhaust Heat Recovery

DOE Office of Scientific and Technical Information (OSTI.GOV)

Conklin, Jim; Szybist, James P

2010-01-01

A concept is presented here that adds two additional strokes to the four-stroke Otto or Diesel cycle that has the potential to increase fuel efficiency of the basic cycle. The engine cycle can be thought of as a 4 stroke Otto or Diesel cycle followed by a 2-stroke heat recovery steam cycle. Early exhaust valve closing during the exhaust stroke coupled with water injection are employed to add an additional power stroke at the end of the conventional four-stroke Otto or Diesel cycle. An ideal thermodynamics model of the exhaust gas compression, water injection at top center, and expansion wasmore » used to investigate this modification that effectively recovers waste heat from both the engine coolant and combustion exhaust gas. Thus, this concept recovers energy from two waste heat sources of current engine designs and converts heat normally discarded to useable power and work. This concept has the potential of a substantial increase in fuel efficiency over existing conventional internal combustion engines, and under appropriate injected water conditions, increase the fuel efficiency without incurring a decrease in power density. By changing the exhaust valve closing angle during the exhaust stroke, the ideal amount of exhaust can be recompressed for the amount of water injected, thereby minimizing the work input and maximizing the mean effective pressure of the steam expansion stroke (MEPsteam). The value of this exhaust valve closing for maximum MEPsteam depends on the limiting conditions of either one bar or the dew point temperature of the expansion gas/moisture mixture when the exhaust valve opens to discard the spent gas mixture in the sixth stroke. The range of MEPsteam calculated for the geometry of a conventional gasoline spark-ignited internal combustion engine and for plausible water injection parameters is from 0.75 to 2.5 bars. Typical combustion mean effective pressures (MEPcombustion) of naturally aspirated gasoline engines are up to 10 bar, thus this concept has the potential to significantly increase the engine efficiency and fuel economy while not resulting in a decrease in power density.« less

Water Electrolyzers and the Zero-Point Energy

NASA Astrophysics Data System (ADS)

King, M. B.

The gas emitted from popular water electrolyzer projects manifests unusual energetic anomalies, which include vaporizing tungsten when used in a welding torch and running internal combustion engines on small quantities of the gas. Some claim to run generators in closed loop fashion solely on the gas from the electrolyzer, which is powered solely from the generator. Most investigators believe the energy is from burning hydrogen. A hypothesis is proposed that the dominant energy is not coming from hydrogen, but rather it is coming from charged water gas clusters, which activate and coherently trap zero-point energy.

A Close Loop Low-Power and High Speed 130 nm CMOS Sample and Hold Circuit Based on Switched Capacitor for ADC Module

NASA Astrophysics Data System (ADS)

Nasir, Z.; Ruslan, S. H.

2017-08-01

A sample and hold (S/H) block is typically used as an analogue to digital interface in the analogue to digital converter (ADC) system. Since ADC is widely used in processing signals, the power consumption of the ADC must be lowered to conserve energy. Therefore the S/H circuit must be of a low powered too. Sampling phase and hold phase are the two phases of the operation cycle of the S/H circuit. Switched capacitor (SC) techniques have been developed in order to allow the integration on a single silicon chip of both digital and analogue functions. By controlling switches around the SC, the SC circuit works by passing charge into and out of a capacitor. SC circuits are suitable for on chip implementations because they replace a resistor with switches and capacitors. In this research, a closed-loop sample and hold circuit based on SC is designed and simulated with Cadence EDA tools. The schematic, layout, and simulation of the circuit is done using generic Silterra 130 nm technology file. All the analysis is done using Virtuoso Analog Design Environment. Layout and schematic are drawn using Virtuoso Schematic Editor and Virtuoso Layout Editor, Calibre is used for post layout simulation. The closed loop S/H circuit based on SC is successfully designed and able to sample and hold the analogue input waveform. The power consumption of the circuit is 0.919 mW and the propagation delay is 64.96 ps.

Controlling calcium precipitation in an integrated anaerobic-aerobic treatment system of a "zero-discharge" paper mill.

PubMed

van Lier, J B; Boncz, M A

2002-01-01

The pulp and paper industry uses significant amounts of water and energy for the paper production process. Closing the water cycles in this industry, therefore, promises large benefits for the environment and has the potential of huge cost savings for the industry. Closing the water cycle on the other hand also introduces problems with process water quality, quality of the end-product and scaling, owing to increased water contamination. An inline treatment system is discussed in which anaerobic-aerobic bioreactors perform a central role for removing both organic and inorganic pollutants from the process water cycle. In the proposed set-up, the organic compounds are converted to methane gas and reused for energy supply, while sulphur compounds are stripped from the process cycle and calcium carbonate is removed by precipitation. Improved control of the treatment system will direct the inorganic precipitates to a location where it does not adversely affect paper production and process water treatment. A simulation program for triggering and controlling CaCO3 precipitation was developed that takes both biological conversions and all relevant chemical equilibria in the system into account. Simulation results are in good agreement with data gathered in a full-scale "zero-emission" paper plant and indicate that control of CaCO3 precipitation can be improved, e.g. in the aerobic post-treatment. Alternatively, a separate precipitation unit could be considered.

Closed-Loop HIRF Experiments Performed on a Fault Tolerant Flight Control Computer

NASA Technical Reports Server (NTRS)

Belcastro, Celeste M.

1997-01-01

ABSTRACT Closed-loop HIRF experiments were performed on a fault tolerant flight control computer (FCC) at the NASA Langley Research Center. The FCC used in the experiments was a quad-redundant flight control computer executing B737 Autoland control laws. The FCC was placed in one of the mode-stirred reverberation chambers in the HIRF Laboratory and interfaced to a computer simulation of the B737 flight dynamics, engines, sensors, actuators, and atmosphere in the Closed-Loop Systems Laboratory. Disturbances to the aircraft associated with wind gusts and turbulence were simulated during tests. Electrical isolation between the FCC under test and the simulation computer was achieved via a fiber optic interface for the analog and discrete signals. Closed-loop operation of the FCC enabled flight dynamics and atmospheric disturbances affecting the aircraft to be represented during tests. Upset was induced in the FCC as a result of exposure to HIRF, and the effect of upset on the simulated flight of the aircraft was observed and recorded. This paper presents a description of these closed- loop HIRF experiments, upset data obtained from the FCC during these experiments, and closed-loop effects on the simulated flight of the aircraft.

Closed-Loop- and Decision-Assist-Guided Fluid Therapy of Human Hemorrhage.

PubMed

Hundeshagen, Gabriel; Kramer, George C; Ribeiro Marques, Nicole; Salter, Michael G; Koutrouvelis, Aristides K; Li, Husong; Solanki, Daneshvari R; Indrikovs, Alexander; Seeton, Roger; Henkel, Sheryl N; Kinsky, Michael P

2017-10-01

We sought to evaluate the efficacy, efficiency, and physiologic consequences of automated, endpoint-directed resuscitation systems and compare them to formula-based bolus resuscitation. Experimental human hemorrhage and resuscitation. Clinical research laboratory. Healthy volunteers. Subjects (n = 7) were subjected to hemorrhage and underwent a randomized fluid resuscitation scheme on separate visits 1) formula-based bolus resuscitation; 2) semiautonomous (decision assist) fluid administration; and 3) fully autonomous (closed loop) resuscitation. Hemodynamic variables, volume shifts, fluid balance, and cardiac function were monitored during hemorrhage and resuscitation. Treatment modalities were compared based on resuscitation efficacy and efficiency. All approaches achieved target blood pressure by 60 minutes. Following hemorrhage, the total amount of infused fluid (bolus resuscitation: 30 mL/kg, decision assist: 5.6 ± 3 mL/kg, closed loop: 4.2 ± 2 mL/kg; p < 0.001), plasma volume, extravascular volume (bolus resuscitation: 17 ± 4 mL/kg, decision assist: 3 ± 1 mL/kg, closed loop: -0.3 ± 0.3 mL/kg; p < 0.001), body weight, and urinary output remained stable under decision assist and closed loop and were significantly increased under bolus resuscitation. Mean arterial pressure initially decreased further under bolus resuscitation (-10 mm Hg; p < 0.001) and was lower under bolus resuscitation than closed loop at 20 minutes (bolus resuscitation: 57 ± 2 mm Hg, closed loop: 69 ± 4 mm Hg; p = 0.036). Colloid osmotic pressure (bolus resuscitation: 19.3 ± 2 mm Hg, decision assist, closed loop: 24 ± 0.4 mm Hg; p < 0.05) and hemoglobin concentration were significantly decreased after bolus fluid administration. We define efficacy of decision-assist and closed-loop resuscitation in human hemorrhage. In comparison with formula-based bolus resuscitation, both semiautonomous and autonomous approaches were more efficient in goal-directed resuscitation of hemorrhage. They provide favorable conditions for the avoidance of over-resuscitation and its adverse clinical sequelae. Decision-assist and closed-loop resuscitation algorithms are promising technological solutions for constrained environments and areas of limited resources.

Bacteriophage in polar inland waters

USGS Publications Warehouse

Säwström, Christin; Lisle, John; Anesio, A.M.; Priscu, John C.; Laybourn-Parry, J.

2008-01-01

Bacteriophages are found wherever microbial life is present and play a significant role in aquatic ecosystems. They mediate microbial abundance, production, respiration, diversity, genetic transfer, nutrient cycling and particle size distribution. Most studies of bacteriophage ecology have been undertaken at temperate latitudes. Data on bacteriophages in polar inland waters are scant but the indications are that they play an active and dynamic role in these microbially dominated polar ecosystems. This review summarises what is presently known about polar inland bacteriophages, ranging from subglacial Antarctic lakes to glacial ecosystems in the Arctic. The review examines interactions between bacteriophages and their hosts and the abiotic and biotic variables that influence these interactions in polar inland waters. In addition, we consider the proportion of the bacteria in Arctic and Antarctic lake and glacial waters that are lysogenic and visibly infected with viruses. We assess the relevance of bacteriophages in the microbial loop in the extreme environments of Antarctic and Arctic inland waters with an emphasis on carbon cycling.

The water cycle in closed ecological systems: perspectives from the Biosphere 2 and Laboratory Biosphere systems

NASA Astrophysics Data System (ADS)

Nelson, Mark; Dempster, William; Allen, John P.

To achieve sustainable and healthy closed ecological systems requires successful solutions to the challenge of closing the water cycle - recycling wastewater/soil leachate and evaporateed water and supplying water of required quality as needed for different needs within the facility. Engineering Biosphere 2, the first multi-biome closed ecological system, total footprint of the airtight area is 12,700 m2 with a combined volume of 200,000 m3 with a total water capacity of some 6 x 106 liters of water presented a complex challenge because it included human inhabitants, their agricultural and technical systems, as well as a range of analogue ecosystems ranging from rainforest to desert, freshwater ecologies to mini-ocean coral reef ecosystems. By contrast, the Laboratory Biosphere - a small (40m3 volume) soil-based plant growth facility with a footprint of 15m3 - is a very simplified system, but with some similar issues such as salinity management and the provision of water quality sufficient for plant growth. In Biosphere 2, water needs included supplying potable water for people and domestic animals, irrigation water for a wide variety of food crops, and recycling and recovering soil nutrients from wastewater. In the wilderness biomes, adequately freshwater was needed for terrestrial ecosystems and maintaining appropriate salinity and pH in aquatic/marine ecosystems. The largest reservoirs in Biosphere 2 were the ocean/marsh with some 4x106 liters, soil with 2 x 106 liters, primary storage tanks with a capacity for up to 8 x 105 liters and storage tanks for condensate collection and mixing tanks with 1.5 x 105 liters to supply irrigation for farm and wilderness ecosystems. Other reservoirs were far smaller - humidity in the atmosphere (2 x 103 liters), streams in the rainforest and savannah, and seasonal pools in the desert were orders of magnitude smaller (8 x 103 liters). Key technologies included condensation from humidity in the airhandlers and from the glass spaceframe to produce high quality freshwater, purification of nutrients from ocean waters with first algae mats and then protein skimmers, wastewater treatment with constructed wetlands and desalination through reverse osmosis and flash evaporation were key to recycling water with appropriate quality throughout the Biosphere 2 facility. Wastewater from all human uses and the domestic animals in Biosphere 2 was treated and recycling through a series of constructed wetlands, which had hydraulic loading of 0.9-1.1 m3 day-1 (240-290 gal d-1). Plant production in the wetland treatment system produced 1210 kg dry weight of emergent and floating aquatic plant wetland used as fodder for the domestic animals and remaining nutrients/water was reused as part of the agricultural irrigation supply. There were pools of water with recycling times of days to weeks and others with far longer cycling times within Biosphere 2. By contrast, the Laboratory Biosphere with a total water reservoir of less than 500 litres has far quicker cycling rapidity. However, just as in Biosphere 2, humidity in the Laboratory Biosphere is a very small reservoir of water. The amount of water passing through the air in the course of a 12-hour operational day is two orders of magnitude greater than the amount stored in the air. Thus evaporation, condensation and soil leachate collection are vital parts of the recycle system just as in Biosphere 2. The water cycle and sustainable water recycling in closed ecological systems presents problems requiring further research to resolve - such as how to control buildup of salinity in materially-closed ecosystems and effective ways to retain nutrients in optimal quantity and useable form for plant growth which are common to closed ecological systems of whatever size. These issues have relevance to a global environment increasingly facing water shortages and the task of maintaining water quality for human and ecosystem health.

Electrochemical Ion-Exchange Regeneration and Fluidized Bed Crystallization for Zero-Liquid-Discharge Water Softening.

PubMed

Chen, Yingying; Davis, Jake R; Nguyen, Chi H; Baygents, James C; Farrell, James

2016-06-07

This research investigated the use of an electrochemical system for regenerating ion-exchange media and for promoting the crystallization of hardness minerals in a fluidized bed crystallization reactor (FBCR). The closed-loop process eliminates the creation of waste brine solutions that are normally produced when regenerating ion-exchange media. A bipolar membrane electrodialysis stack was used to generate acids and bases from 100 mM salt solutions. The acid was used to regenerate weak acid cation (WAC) ion-exchange media used for water softening. The base solutions were used to absorb CO2 gas and to provide a source of alkalinity for removing noncarbonate hardness by WAC media operated in H(+) form. The base solutions were also used to promote the crystallization of CaCO3 and Mg(OH)2 in a FBCR. The overall process removes hardness ions from the water being softened and replaces them with H(+) ions, slightly decreasing the pH value of the softened water. The current utilization efficiency for acid and base production was ∼75% over the operational range of interest, and the energy costs for producing acids and bases were an order of magnitude lower than the costs for purchasing acid and base in bulk quantities. Ion balances indicate that the closed-loop system will accumulate SO4(2-), Cl(-), and alkali metal ions. Acid and base balances indicate that for a typical water, small amounts of base will be accumulated.

Atmospheric Water Balance and Variability in the MERRA-2 Reanalysis

NASA Technical Reports Server (NTRS)

Bosilovich, Michael G.; Robertson, Franklin R.; Takacs, Lawrence; Molod, Andrea; Mocko, David

2017-01-01

Closing and balancing Earths global water cycle remains a challenge for the climate community. Observations are limited in duration, global coverage, and frequency, and not all water cycle terms are adequately observed. Reanalyses aim to fill the gaps through the assimilation of as many atmospheric water vapor observations as possible. Former generations of reanalyses have demonstrated a number of systematic problems that have limited their use in climate studies, especially regarding low-frequency trends. This study characterizes the NASA Modern-Era Retrospective Analysis for Research and Applications version 2 (MERRA-2) water cycle relative to contemporary reanalyses and observations. MERRA-2 includes measures intended to minimize the spurious global variations related to in homogeneity in the observational record. The global balance and cycling of water from ocean to land is presented, with special attention given to the water vapor analysis increment and the effects of the changing observing system. While some systematic regional biases can be identified,MERRA-2 produces temporally consistent time series of total column water and transport of water from ocean to land. However, the interannual variability of ocean evaporation is affected by the changing surface-wind-observing system, and precipitation variability is closely related to the evaporation. The surface energy budget is also strongly influenced by the interannual variability of the ocean evaporation. Furthermore, evaluating the relationship of temperature and water vapor indicates that the variations of water vapor with temperature are weaker in satellite data reanalyses, not just MERRA-2, than determined by observations, atmospheric models, or reanalyses without water vapor assimilation.

CLOSED-LOOP STRIPPING ANALYSIS (CLSA) OF SYNTHETIC MUSK COMPOUNDS FROM FISH TISSUES WITH MEASUREMENT BY GAS CHROMATOGRAPHY-MASS SPECTROMETRY WITH SELECTED-ION MONITORING

EPA Science Inventory

Synthetic musk compounds have been found in surface water, fish tissues, and human breast milk. Current techniques for separating these compounds from fish tissues require tedious sample clean-upprocedures A simple method for the deterrnination of these compounds in fish tissues ...

Closing the Loop--Improving Energy Management in Schools. Energy Research Group Report.

ERIC Educational Resources Information Center

Isaacs, Nigel; Donn, Michael

A study of the energy savings potential in New Zealand schools demonstrates that considerable reductions in energy costs can be achieved through energy management. An initial examination of available 1985 light, heat, and water expenditures for 268 secondary schools (84 percent of the secondary schools in New Zealand) is followed by the selection…

Control of Supercavitating Vehicles using Transverse Jets

DTIC Science & Technology

2016-03-15

Experimental Technique All experiments reported here were conducted at the Naval Undersea Warfare Center (NUWC) closed loop research water tunnel in Newport...mass of moving parts of the assembly. The second element considered was tte loss term associated with flow restriction across the orifice which was...W. Henoch, Hydrodynamics Branch, Naval Undersea Warfare Center, Newport, RI. 49

CLOSED-LOOP STRIPPING ANALYSIS (CLSA) OF SYNTHETIC MUSK COMPOUNDS FROM FISH TISSUES WITH MEASUREMENT BY OC/MS/SIM

EPA Science Inventory

Synthetic musk compounds are used as inexpensive fragrance materials for the production
of perfumes and as additives to soap, detergent, and shampoo. They have been found in surface water, fish tissues, and human breast milk. The ubiquity of this class of compounds in the env...

Predictive lethal proarrhythmic risk evaluation using a closed-loop-circuit cell network with human induced pluripotent stem cells derived cardiomyocytes

NASA Astrophysics Data System (ADS)

Nomura, Fumimasa; Hattori, Akihiro; Terazono, Hideyuki; Kim, Hyonchol; Odaka, Masao; Sugio, Yoshihiro; Yasuda, Kenji

2016-06-01

For the prediction of lethal arrhythmia occurrence caused by abnormality of cell-to-cell conduction, we have developed a next-generation in vitro cell-to-cell conduction assay, i.e., a quasi in vivo assay, in which the change in spatial cell-to-cell conduction is quantitatively evaluated from the change in waveforms of the convoluted electrophysiological signals from lined-up cardiomyocytes on a single closed loop of a microelectrode of 1 mm diameter and 20 µm width in a cultivation chip. To evaluate the importance of the closed-loop arrangement of cardiomyocytes for prediction, we compared the change in waveforms of convoluted signals of the responses in the closed-loop circuit arrangement with that of the response of cardiomyocyte clusters using a typical human ether a go-go related gene (hERG) ion channel blocker, E-4031. The results showed that (1) waveform prolongation and fluctuation both in the closed loops and clusters increased depending on the E-4031 concentration increase. However, (2) only the waveform signals in closed loops showed an apparent temporal change in waveforms from ventricular tachycardia (VT) to ventricular fibrillation (VF), which is similar to the most typical cell-to-cell conductance abnormality. The results indicated the usefulness of convoluted waveform signals of a closed-loop cell network for acquiring reproducible results acquisition and more detailed temporal information on cell-to-cell conduction.

Design and Certification of the Extravehicular Activity Mobility Unit (EMU) Water Processing Jumper

NASA Technical Reports Server (NTRS)

Peterson, Laurie J.; Neumeyer, Derek J.; Lewis, John F.

2006-01-01

The Extravehicular Mobility Units (EMUs) onboard the International Space Station (ISS) experienced a failure due to cooling water contamination from biomass and corrosion byproducts forming solids around the EMU pump rotor. The coolant had no biocide and a low pH which induced biofilm growth and corrosion precipitates, respectively. NASA JSC was tasked with building hardware to clean the ionic, organic, and particulate load from the EMU coolant loop before and after Extravehicular Activity (EVAs). Based on a return sample of the EMU coolant loop, the chemical load was well understood, but there was not sufficient volume of the returned sample to analyze particulates. Through work with EMU specialists, chemists, (EVA) Mission Operations Directorate (MOD) representation, safety and mission assurance, astronaut crew, and team engineers, requirements were developed for the EMU Water Processing hardware (sometimes referred to as the Airlock Coolant Loop Recovery [A/L CLR] system). Those requirements ranged from the operable level of ionic, organic, and particulate load, interfaces to the EMU, maximum cycle time, operating pressure drop, flow rate, and temperature, leakage rates, and biocide levels for storage. Design work began in February 2005 and certification was completed in April 2005 to support a return to flight launch date of May 12, 2005. This paper will discuss the details of the design and certification of the EMU Water Processing hardware and its components

Status of the DOE /STOR/-sponsored national program on hydrogen production from water via thermochemical cycles

NASA Technical Reports Server (NTRS)

Baker, C. E.

1977-01-01

A pure thermochemical cycle is a system of linked regenerative chemical reactions which accepts only water and heat and produces hydrogen. Thermochemical cycles are potentially a more efficient and cheaper means of producing hydrogen from water than is the generation of electricity followed by electrolysis. The Energy Storage Systems Division of the Department of Energy is currently funding a national program on thermochemical hydrogen production. The National Aeronautics and Space Administration is responsible for the technical management of this program. The goal is to develop a cycle which can potentially operate with an efficiency greater than 40% using a heat source providing a maximum available temperature of 1150 K. A closed bench-scale demonstration of such a cycle would follow. This cycle would be labeled a 'reference cycle' and would serve as a baseline against which future cycles would be compared.

Closing the Loop: A Study of How the National Survey of Student Engagement (NSSE) Is Used for Decision-Making and Planning in Student Affairs

ERIC Educational Resources Information Center

McCaul, Jennifer Lee

2015-01-01

"Closing the loop" is a commonly used phrase in discussing cyclical processes, such as the area of outcomes assessment in higher education. Increased interest in accountability and a shift in accreditation focus have necessitated that higher education institutions are closing the assessment loop and creating a culture of evidence to…

Tonic accommodation predicts closed-loop accommodation responses.

PubMed

Liu, Chunming; Drew, Stefanie A; Borsting, Eric; Escobar, Amy; Stark, Lawrence; Chase, Christopher

2016-12-01

The purpose of this study is to examine the potential relationship between tonic accommodation (TA), near work induced TA-adaptation and the steady state closed-loop accommodation response (AR). Forty-two graduate students participated in the study. Various aspects of their accommodation system were objectively measured using an open-field infrared auto-refractor (Grand Seiko WAM-5500). Tonic accommodation was assessed in a completely dark environment. The association between TA and closed-loop AR was assessed using linear regression correlations and t-test comparisons. Initial mean baseline TA was 1.84diopter (D) (SD±1.29D) with a wide distribution range (-0.43D to 5.14D). For monocular visual tasks, baseline TA was significantly correlated with the closed-loop AR. The slope of the best fit line indicated that closed-loop AR varied by approximately 0.3D for every 1D change in TA. This ratio was consistent across a variety of viewing distances and different near work tasks, including both static targets and continuous reading. Binocular reading conditions weakened the correlation between baseline TA and AR, although results remained statistically significant. The 10min near reading task with a 3D demand did not reveal significant near work induced TA-adaptation for either monocular or binocular conditions. Consistently, the TA-adaptation did not show any correlation with AR during reading. This study found a strong association between open-loop TA and closed-loop AR across a variety of viewing distances and different near work tasks. Difference between the correlations under monocular and binocular reading condition suggests a potential role for vergence compensation during binocular closed-loop AR. Copyright © 2016 Elsevier Ltd. All rights reserved.

Dynamic Testing of the NASA Hypersonic Project Combined Cycle Engine Testbed for Mode Transition Experiments

NASA Technical Reports Server (NTRS)

2011-01-01

NASA is interested in developing technology that leads to more routine, safe, and affordable access to space. Access to space using airbreathing propulsion systems has potential to meet these objectives based on Airbreathing Access to Space (AAS) system studies. To this end, the NASA Fundamental Aeronautics Program (FAP) Hypersonic Project is conducting fundamental research on a Turbine Based Combined Cycle (TBCC) propulsion system. The TBCC being studied considers a dual flow-path inlet system. One flow-path includes variable geometry to regulate airflow to a turbine engine cycle. The turbine cycle provides propulsion from take-off to supersonic flight. The second flow-path supports a dual-mode scramjet (DMSJ) cycle which would be initiated at supersonic speed to further accelerate the vehicle to hypersonic speed. For a TBCC propulsion system to accelerate a vehicle from supersonic to hypersonic speed, a critical enabling technology is the ability to safely and effectively transition from the turbine to the DMSJ-referred to as mode transition. To experimentally test methods of mode transition, a Combined Cycle Engine (CCE) Large-scale Inlet testbed was designed with two flow paths-a low speed flow-path sized for a turbine cycle and a high speed flow-path designed for a DMSJ. This testbed system is identified as the CCE Large-Scale Inlet for Mode Transition studies (CCE-LIMX). The test plan for the CCE-LIMX in the NASA Glenn Research Center (GRC) 10- by 10-ft Supersonic Wind Tunnel (10x10 SWT) is segmented into multiple phases. The first phase is a matrix of inlet characterization (IC) tests to evaluate the inlet performance and establish the mode transition schedule. The second phase is a matrix of dynamic system identification (SysID) experiments designed to support closed-loop control development at mode transition schedule operating points for the CCE-LIMX. The third phase includes a direct demonstration of controlled mode transition using a closed loop control system developed with the data obtained from the first two phases. Plans for a fourth phase include mode transition experiments with a turbine engine. This paper, focusing on the first two phases of experiments, presents developed operational and analysis tools for streamlined testing and data reduction procedures.

Double closed-loop cascade control for lower limb exoskeleton with elastic actuation.

PubMed

Zhu, Yanhe; Zheng, Tianjiao; Jin, Hongzhe; Yang, Jixing; Zhao, Jie

2015-01-01

Unlike traditional rigid actuators, the significant features of Series Elastic Actuator (SEA) are stable torque control, lower output impedance, impact resistance and energy storage. Recently, SEA has been applied in many exoskeletons. In such applications, a key issue is how to realize the human-exoskeleton movement coordination. In this paper, double closed-loop cascade control for lower limb exoskeleton with SEA is proposed. This control method consists of inner SEA torque loop and outer contact force loop. Utilizing the SEA torque control with a motor velocity loop, actuation performances of SEA are analyzed. An integrated exoskeleton control system is designed, in which joint angles are calculated by internal encoders and resolvers and contact forces are gathered by external pressure sensors. The double closed-loop cascade control model is established based on the feedback signals of internal and external sensor. Movement experiments are accomplished in our prototype of lower limb exoskeleton. Preliminary results indicate the exoskeleton movements with pilot can be realized stably by utilizing this double closed-loop cascade control method. Feasibility of the SEA in our exoskeleton robot and effectiveness of the control method are verified.

Closed-loop analysis and control of a non-inverting buck-boost converter

NASA Astrophysics Data System (ADS)

Chen, Zengshi; Hu, Jiangang; Gao, Wenzhong

2010-11-01

In this article, a cascade controller is designed and analysed for a non-inverting buck-boost converter. The fast inner current loop uses sliding mode control. The slow outer voltage loop uses the proportional-integral (PI) control. Stability analysis and selection of PI gains are based on the nonlinear closed-loop error dynamics incorporating both the inner and outer loop controllers. The closed-loop system is proven to have a nonminimum phase structure. The voltage transient due to step changes of input voltage or resistance is predictable. The operating range of the reference voltage is discussed. The controller is validated by a simulation circuit. The simulation results show that the reference output voltage is well-tracked under system uncertainties or disturbances, confirming the validity of the proposed controller.

Process for thermochemically producing hydrogen

DOEpatents

Bamberger, Carlos E.; Richardson, Donald M.

1976-01-01

Hydrogen is produced by the reaction of water with chromium sesquioxide and strontium oxide. The hydrogen producing reaction is combined with other reactions to produce a closed chemical cycle for the thermal decomposition of water.

Ingham County Geriatric Medical Care Facility solar water-heating system refurbishments. Final technical report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

The tasks of the refurbishment of a damaged solar water heating system are outlined. The system is a closed loop, 50% glycol antifreeze system consisting of 14 rows of 6 series manifolds each containing 6 solar collectors connected in parallel for a total of 504 modules. The Wyle Laboratories' test report for the Revere Model 132 flat plate collector is appended. A collector test plan and photographs are also appended. Reference CAPE-2834. (LS)

Window-closing safety system

DOEpatents

McEwan, Thomas E.

1997-01-01

A safety device includes a wire loop embedded in the glass of a passenger car window and routed near the closing leading-edge of the window. The wire loop carries microwave pulses around the loop to and from a transceiver with separate output and input ports. An evanescent field only and inch or two in radius is created along the wire loop by the pulses. Just about any object coming within the evanescent field will dramatically reduce the energy of the microwave pulses received back by the transceiver. Such a loss in energy is interpreted as a closing area blockage, and electrical interlocks are provided to halt or reverse a power window motor that is actively trying to close the window.

Window-closing safety system

DOEpatents

McEwan, T.E.

1997-08-26

A safety device includes a wire loop embedded in the glass of a passenger car window and routed near the closing leading-edge of the window. The wire loop carries microwave pulses around the loop to and from a transceiver with separate output and input ports. An evanescent field only an inch or two in radius is created along the wire loop by the pulses. Just about any object coming within the evanescent field will dramatically reduce the energy of the microwave pulses received back by the transceiver. Such a loss in energy is interpreted as a closing area blockage, and electrical interlocks are provided to halt or reverse a power window motor that is actively trying to close the window. 5 figs.

Comparison of control structures for a bidirectional high-frequency dc-dc converter

NASA Astrophysics Data System (ADS)

Himmelstoss, Felix A.; Kolar, Johann W.; Zach, Franz C.

1989-08-01

A system for dc-dc power conversion based on a buck-boost converter topology is presented. It makes power flow in both directions possible. The possibility of bidirectional power flow is useful for certain applications, such as uninterruptable power supplies. Starting from a structural diagram the transfer function of the system is derived. The controller for the converter is then designed. It is made up of a simple voltage controller, a voltage controller with an inner loop current controller (cascade control) and with two kinds of state space control. The transfer functions of the different system parts are derived and dimensioning guidelines for the controller sections are presented. The closed loop behavior of the bidirectional converter for the different control structures is analyzed based on simulation using duty cycle averaging. Bodediagrams and step responses are shown.

A Sensor Failure Simulator for Control System Reliability Studies

NASA Technical Reports Server (NTRS)

Melcher, K. J.; Delaat, J. C.; Merrill, W. C.; Oberle, L. G.; Sadler, G. G.; Schaefer, J. H.

1986-01-01

A real-time Sensor Failure Simulator (SFS) was designed and assembled for the Advanced Detection, Isolation, and Accommodation (ADIA) program. Various designs were considered. The design chosen features an IBM-PC/XT. The PC is used to drive analog circuitry for simulating sensor failures in real-time. A user defined scenario describes the failure simulation for each of the five incoming sensor signals. Capabilities exist for editing, saving, and retrieving the failure scenarios. The SFS has been tested closed-loop with the Controls Interface and Monitoring (CIM) unit, the ADIA control, and a real-time F100 hybrid simulation. From a productivity viewpoint, the menu driven user interface has proven to be efficient and easy to use. From a real-time viewpoint, the software controlling the simulation loop executes at greater than 100 cycles/sec.

A sensor failure simulator for control system reliability studies

NASA Astrophysics Data System (ADS)

Melcher, K. J.; Delaat, J. C.; Merrill, W. C.; Oberle, L. G.; Sadler, G. G.; Schaefer, J. H.

A real-time Sensor Failure Simulator (SFS) was designed and assembled for the Advanced Detection, Isolation, and Accommodation (ADIA) program. Various designs were considered. The design chosen features an IBM-PC/XT. The PC is used to drive analog circuitry for simulating sensor failures in real-time. A user defined scenario describes the failure simulation for each of the five incoming sensor signals. Capabilities exist for editing, saving, and retrieving the failure scenarios. The SFS has been tested closed-loop with the Controls Interface and Monitoring (CIM) unit, the ADIA control, and a real-time F100 hybrid simulation. From a productivity viewpoint, the menu driven user interface has proven to be efficient and easy to use. From a real-time viewpoint, the software controlling the simulation loop executes at greater than 100 cycles/sec.

Structural robustness with suboptimal responses for linear state space model

NASA Technical Reports Server (NTRS)

Keel, L. H.; Lim, Kyong B.; Juang, Jer-Nan

1989-01-01

A relationship between the closed-loop eigenvalues and the amount of perturbations in the open-loop matrix is addressed in the context of performance robustness. If the allowable perturbation ranges of elements of the open-loop matrix A and the desired tolerance of the closed-loop eigenvalues are given such that max(j) of the absolute value of Delta-lambda(j) (A+BF) should be less than some prescribed value, what is a state feedback controller F which satisfies the closed-loop eigenvalue perturbation-tolerance requirement for a class of given perturbation in A? The paper gives an algorithm to design such a controller. Numerical examples are included for illustration.

Bidirectional neural interface: Closed-loop feedback control for hybrid neural systems.

PubMed

Chou, Zane; Lim, Jeffrey; Brown, Sophie; Keller, Melissa; Bugbee, Joseph; Broccard, Frédéric D; Khraiche, Massoud L; Silva, Gabriel A; Cauwenberghs, Gert

2015-01-01

Closed-loop neural prostheses enable bidirectional communication between the biological and artificial components of a hybrid system. However, a major challenge in this field is the limited understanding of how these components, the two separate neural networks, interact with each other. In this paper, we propose an in vitro model of a closed-loop system that allows for easy experimental testing and modification of both biological and artificial network parameters. The interface closes the system loop in real time by stimulating each network based on recorded activity of the other network, within preset parameters. As a proof of concept we demonstrate that the bidirectional interface is able to establish and control network properties, such as synchrony, in a hybrid system of two neural networks more significantly more effectively than the same system without the interface or with unidirectional alternatives. This success holds promise for the application of closed-loop systems in neural prostheses, brain-machine interfaces, and drug testing.

Domain Hierarchy and closed Loops (DHcL): a server for exploring hierarchy of protein domain structure

PubMed Central

Koczyk, Grzegorz; Berezovsky, Igor N.

2008-01-01

Domain hierarchy and closed loops (DHcL) (http://sitron.bccs.uib.no/dhcl/) is a web server that delineates energy hierarchy of protein domain structure and detects domains at different levels of this hierarchy. The server also identifies closed loops and van der Waals locks, which constitute a structural basis for the protein domain hierarchy. The DHcL can be a useful tool for an express analysis of protein structures and their alternative domain decompositions. The user submits a PDB identifier(s) or uploads a 3D protein structure in a PDB format. The results of the analysis are the location of domains at different levels of hierarchy, closed loops, van der Waals locks and their interactive visualization. The server maintains a regularly updated database of domains, closed loop and van der Waals locks for all X-ray structures in PDB. DHcL server is available at: http://sitron.bccs.uib.no/dhcl. PMID:18502776

Novel imaging closed loop control strategy for heliostats

NASA Astrophysics Data System (ADS)

Bern, Gregor; Schöttl, Peter; Heimsath, Anna; Nitz, Peter

2017-06-01

Central Receiver Systems use up to thousands of heliostats to concentrate solar radiation. The precise control of heliostat aiming points is crucial not only for efficiency but also for reliable plant operation. Besides the calibration of open loop control systems, closed loop tracking strategies are developed to address a precise and efficient aiming strategy. The need for cost reductions in the heliostat field intensifies the motivation for economic closed loop control systems. This work introduces an approach for a closed loop heliostat tracking strategy using image analysis and signal modulation. The approach aims at the extraction of heliostat focal spot position within the receiver domain by means of a centralized remote vision system decoupled from the rough conditions close to the focal area. Taking an image sequence of the receiver while modulating a signal on different heliostats, their aiming points are retrieved. The work describes the methodology and shows first results from simulations and practical tests performed in small scale, motivating further investigation and deployment.

The influence of visual feedback from the recent past on the programming of grip aperture is grasp-specific, shared between hands, and mediated by sensorimotor memory not task set.

PubMed

Tang, Rixin; Whitwell, Robert L; Goodale, Melvyn A

2015-05-01

Goal-directed movements, such as reaching out to grasp an object, are necessarily constrained by the spatial properties of the target such as its size, shape, and position. For example, during a reach-to-grasp movement, the peak width of the aperture formed by the thumb and fingers in flight (peak grip aperture, PGA) is linearly related to the target's size. Suppressing vision throughout the movement (visual open loop) has a small though significant effect on this relationship. Visual open loop conditions also produce a large increase in the PGA compared to when vision is available throughout the movement (visual closed loop). Curiously, this differential effect of the availability of visual feedback is influenced by the presentation order: the difference in PGA between closed- and open-loop trials is smaller when these trials are intermixed (an effect we have called 'homogenization'). Thus, grasping movements are affected not only by the availability of visual feedback (closed loop or open loop) but also by what happened on the previous trial. It is not clear, however, whether this carry-over effect is mediated through motor (or sensorimotor) memory or through the interference of different task sets for closed-loop and open-loop feedback that determine when the movements are fully specified. We reasoned that sensorimotor memory, but not a task set for closed and open loop feedback, would be specific to the type of response. We tested this prediction in a condition in which pointing to targets was alternated with grasping those same targets. Critically, in this condition, when pointing was performed in open loop, grasping was always performed in closed loop (and vice versa). Despite the fact that closed- and open-loop trials were alternating in this condition, we found no evidence for homogenization of the PGA. Homogenization did occur, however, in a follow-up experiment in which grasping movements and visual feedback were alternated between the left and the right hand, indicating that sensorimotor (or motor) memory can operate both within and between hands when the response type is kept the same. In a final experiment, we ruled out the possibility that simply alternating the hand used to perform the grasp interferes with motor or sensorimotor memory. We did this by showing that when the hand was alternated within a block of exclusively closed- or open-loop trials, homogenization of the PGA did not occur. Taken together, the results suggest that (1) interference from simply switching between task sets for closed or open-loop feedback or from switching between the hands cannot account homogenization in the PGA and that (2) the programming and execution of grasps can borrow not only from grasping movements executed in the past by the same hand, but also from grasping movements executed with the other hand. Copyright © 2015 Elsevier B.V. All rights reserved.

Time delay compensation for closed-loop insulin delivery systems: a simulation study.

PubMed

Reboldi, G P; Home, P D; Calabrese, G; Fabietti, P G; Brunetti, P; Massi Benedetti, M

1991-06-01

Closed loop insulin therapy certainly represents the best possible approach to insulin replacement. However, present limitations preclude wider application of the so-called artificial pancreas. Therefore, a thorough understanding of these limitations is needed to design better systems for future long-term use. The present simulation study was design: to obtain better information on the impact of the measurement delay of currently available closed-loop devices both during closed-loop insulin delivery and blood glucose clamp studies, and to design and test a time delay compensator based on the method originally described by O.J. Smith. Simulations were performed on a Compaq Deskpro 486/25 personal computer under MS-DOS operating system using Simnon rel. 3.00 software. There was a direct relationship between measurement delay and amount of insulin delivered, i.e., the longer the delay the higher the insulin dose needed to control a rise in blood glucose; the closed-loop response in presence of a time delay was qualitatively impaired both during insulin delivery and blood glucose clamp studies; time delay compensation was effective in reducing the insulin dose and improving controller stability during the early phase of clamp studies. However, the robustness of a Smith's predictor-based controller should be carefully evaluated before implementation in closed-loop systems can be considered.

A review of implantable biosensors for closed-loop glucose control and other drug delivery applications.

PubMed

Scholten, Kee; Meng, Ellis

2018-06-15

Closed-loop drug delivery promises autonomous control of pharmacotherapy through the continuous monitoring of biomarker levels. For decades, researchers have strived for portable closed-loop systems capable of treating ambulatory patients with chronic conditions such as diabetes mellitus. After years of development, the first of these systems have left the laboratory and entered commercial use. This long-awaited advance reflects recent development of chronically stable implantable biosensors able to accurately measure biomarker levels in vivo. This review discusses the role of implantable biosensors in closed-loop drug delivery applications, with the intent to provide a resource for engineers and researchers studying such systems. We provide an overview of common biosensor designs and review the principle challenges in implementing long indwelling sensors: namely device sensitivity, selectivity, and lifetime. This review examines novel advances in transducer design, biological interface, and material biocompatibility, with a focus on recent academic and commercial work which provide successful strategies to overcome perennial challenges. This review focuses primarily on the topics of closed-loop glucose control and continuous glucose monitoring biosensors, which make up the overwhelming majority of published research in this area. We conclude with an overview of recent advances in closed-loop systems targeting applications outside blood glucose management. Copyright © 2018 Elsevier B.V. All rights reserved.

Irradiation Testing Vehicles for Fast Reactors from Open Test Assemblies to Closed Loops

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sienicki, James J.; Grandy, Christopher

A review of irradiation testing vehicle approaches and designs that have been incorporated into past Sodium-Cooled Fast Reactors (SFRs) or envisioned for incorporation has been carried out. The objective is to understand the essential features of the approaches and designs so that they can inform test vehicle designs for a future U.S. Fast Test Reactor. Fast test reactor designs examined include EBR-II, FFTF, JOYO, BOR-60, PHÉNIX, JHR, and MBIR. Previous designers exhibited great ingenuity in overcoming design and operational challenges especially when the original reactor plant’s mission changed to an irradiation testing mission as in the EBRII reactor plant. Themore » various irradiation testing vehicles can be categorized as: Uninstrumented open assemblies that fit into core locations; Instrumented open test assemblies that fit into special core locations; Self-contained closed loops; and External closed loops. A special emphasis is devoted to closed loops as they are regarded as a very desirable feature of a future U.S. Fast Test Reactor. Closed loops are an important technology for irradiation of fuels and materials in separate controlled environments. The impact of closed loops on the design of fast reactors is also discussed in this report.« less

Pre-frontal control of closed-loop limbic neurostimulation by rodents using a brain-computer interface

NASA Astrophysics Data System (ADS)

Widge, Alik S.; Moritz, Chet T.

2014-04-01

Objective. There is great interest in closed-loop neurostimulators that sense and respond to a patient's brain state. Such systems may have value for neurological and psychiatric illnesses where symptoms have high intraday variability. Animal models of closed-loop stimulators would aid preclinical testing. We therefore sought to demonstrate that rodents can directly control a closed-loop limbic neurostimulator via a brain-computer interface (BCI). Approach. We trained rats to use an auditory BCI controlled by single units in prefrontal cortex (PFC). The BCI controlled electrical stimulation in the medial forebrain bundle, a limbic structure involved in reward-seeking. Rigorous offline analyses were performed to confirm volitional control of the neurostimulator. Main results. All animals successfully learned to use the BCI and neurostimulator, with closed-loop control of this challenging task demonstrated at 80% of PFC recording locations. Analysis across sessions and animals confirmed statistically robust BCI control and specific, rapid modulation of PFC activity. Significance. Our results provide a preliminary demonstration of a method for emotion-regulating closed-loop neurostimulation. They further suggest that activity in PFC can be used to control a BCI without pre-training on a predicate task. This offers the potential for BCI-based treatments in refractory neurological and mental illness.

A Graphical Method for Estimation of Barometric Efficiency from Continuous Data - Concepts and Application to a Site in the Piedmont, Air Force Plant 6, Marietta, Georgia

USGS Publications Warehouse

Gonthier, Gerard

2007-01-01

A graphical method that uses continuous water-level and barometric-pressure data was developed to estimate barometric efficiency. A plot of nearly continuous water level (on the y-axis), as a function of nearly continuous barometric pressure (on the x-axis), will plot as a line curved into a series of connected elliptical loops. Each loop represents a barometric-pressure fluctuation. The negative of the slope of the major axis of an elliptical loop will be the ratio of water-level change to barometric-pressure change, which is the sum of the barometric efficiency plus the error. The negative of the slope of the preferred orientation of many elliptical loops is an estimate of the barometric efficiency. The slope of the preferred orientation of many elliptical loops is approximately the median of the slopes of the major axes of the elliptical loops. If water-level change that is not caused by barometric-pressure change does not correlate with barometric-pressure change, the probability that the error will be greater than zero will be the same as the probability that it will be less than zero. As a result, the negative of the median of the slopes for many loops will be close to the barometric efficiency. The graphical method provided a rapid assessment of whether a well was affected by barometric-pressure change and also provided a rapid estimate of barometric efficiency. The graphical method was used to assess which wells at Air Force Plant 6, Marietta, Georgia, had water levels affected by barometric-pressure changes during a 2003 constant-discharge aquifer test. The graphical method was also used to estimate barometric efficiency. Barometric-efficiency estimates from the graphical method were compared to those of four other methods: average of ratios, median of ratios, Clark, and slope. The two methods (the graphical and median-of-ratios methods) that used the median values of water-level change divided by barometric-pressure change appeared to be most resistant to error caused by barometric-pressure-independent water-level change. The graphical method was particularly resistant to large amounts of barometric-pressure-independent water-level change, having an average and standard deviation of error for control wells that was less than one-quarter that of the other four methods. When using the graphical method, it is advisable that more than one person select the slope or that the same person fits the same data several times to minimize the effect of subjectivity. Also, a long study period should be used (at least 60 days) to ensure that loops affected by large amounts of barometric-pressure-independent water-level change do not significantly contribute to error in the barometric-efficiency estimate.

Design and Off-design Performance of 100 Kwe-class Brayton Power Conversion Systems

NASA Technical Reports Server (NTRS)

Johnson, Paul K.; Mason, Lee S.

2005-01-01

The NASA Glenn Research Center in-house computer model Closed Cycle Engine Program (CCEP) was used to explore the design trade space and off-design performance characteristics of 100 kWe-class recuperated Closed Brayton Cycle (CBC) power conversion systems. Input variables for a potential design point included the number of operating units (1, 2, 4), cycle peak pressure (0.5, 1, 2 MPa), and turbo-alternator shaft speed (30, 45, 60 kRPM). The design point analysis assumed a fixed turbine inlet temperature (1150 K), compressor inlet temperature (400 K), working-fluid molecular weight (40 g/mol), compressor pressure ratio (2.0), recuperator effectiveness (0.95), and a Sodium-Potassium (NaK) pumped-loop radiator. The design point options were compared on the basis of thermal input power, radiator area, and mass. For a nominal design point with defined Brayton components and radiator area, off-design cases were examined by reducing turbine inlet temperature (as low as 900 K), reducing shaft speed (as low as 50% of nominal), and circulating a percentage (up to 20%) of the compressor exit flow back to the gas cooler. The off-design examination sought approaches to reduce thermal input power without freezing the radiator.

Effect of closed-loop order processing on the time to initial antimicrobial therapy.

PubMed

Panosh, Nicole; Rew, Richardd; Sharpe, Michelle

2012-08-15

The results of a study comparing the average time to initiation of i.v. antimicrobial therapy with closed-versus open-loop order entry and processing are reported. A retrospective cohort study was performed to compare order-to-administration times for initial doses of i.v. antimicrobials before and after a closed-loop order-processing system including computerized prescriber order entry (CPOE) was implemented at a large medical center. A total of 741 i.v. antimicrobial administrations to adult patients during designated five-month preimplementation and postimplementation study periods were assessed. Drug-use reports generated by the pharmacy database were used to identify order-entry times, and medication administration records were reviewed to determine times of i.v. antimicrobial administration. The mean ± S.D. order-to-administration times before and after the implementation of the CPOE system and closed-loop order processing were 3.18 ± 2.60 and 2.00 ± 1.89 hours, respectively, a reduction of 1.18 hours (p < 0.0001). Closed-loop order processing was associated with significant reductions in the average time to initiation of i.v. therapy in all patient care areas evaluated (cardiology, general medicine, and oncology). The study results suggest that CPOE-based closed-loop order processing can play an important role in achieving compliance with current practice guidelines calling for increased efforts to ensure the prompt initiation of i.v. antimicrobials for severe infections (e.g., sepsis, meningitis). Implementation of a closed-loop order-processing system resulted in a significant decrease in order-to-administration times for i.v. antimicrobial therapy.

An investigation into closed-loop treatment of neurological disorders based on sensing mitochondrial dysfunction.

PubMed

Adams, Scott D; Kouzani, Abbas Z; Tye, Susannah J; Bennet, Kevin E; Berk, Michael

2018-02-13

Dynamic feedback based closed-loop medical devices offer a number of advantages for treatment of heterogeneous neurological conditions. Closed-loop devices integrate a level of neurobiological feedback, which allows for real-time adjustments to be made with the overarching aim of improving treatment efficacy and minimizing risks for adverse events. One target which has not been extensively explored as a potential feedback component in closed-loop therapies is mitochondrial function. Several neurodegenerative and psychiatric disorders including Parkinson's disease, Major Depressive disorder and Bipolar disorder have been linked to perturbations in the mitochondrial respiratory chain. This paper investigates the potential to monitor this mitochondrial function as a method of feedback for closed-loop neuromodulation treatments. A generic model of the closed-loop treatment is developed to describe the high-level functions of any system designed to control neural function based on mitochondrial response to stimulation, simplifying comparison and future meta-analysis. This model has four key functional components including: a sensor, signal manipulator, controller and effector. Each of these components are described and several potential technologies for each are investigated. While some of these candidate technologies are quite mature, there are still technological gaps remaining. The field of closed-loop medical devices is rapidly evolving, and whilst there is a lot of interest in this area, widespread adoption has not yet been achieved due to several remaining technological hurdles. However, the significant therapeutic benefits offered by this technology mean that this will be an active area for research for years to come.

Sensory feedback in prosthetics: a standardized test bench for closed-loop control.

PubMed

Dosen, Strahinja; Markovic, Marko; Hartmann, Cornelia; Farina, Dario

2015-03-01

Closing the control loop by providing sensory feedback to the user of a prosthesis is an important challenge, with major impact on the future of prosthetics. Developing and comparing closed-loop systems is a difficult task, since there are many different methods and technologies that can be used to implement each component of the system. Here, we present a test bench developed in Matlab Simulink for configuring and testing the closed-loop human control system in standardized settings. The framework comprises a set of connected generic blocks with normalized inputs and outputs, which can be customized by selecting specific implementations from a library of predefined components. The framework is modular and extensible and it can be used to configure, compare and test different closed-loop system prototypes, thereby guiding the development towards an optimal system configuration. The use of the test bench was demonstrated by investigating two important aspects of closed-loop control: performance of different electrotactile feedback interfaces (spatial versus intensity coding) during a pendulum stabilization task and feedforward methods (joystick versus myocontrol) for force control. The first experiment demonstrated that in the case of trained subjects the intensity coding might be superior to spatial coding. In the second experiment, the control of force was rather poor even with a stable and precise control interface (joystick), demonstrating that inherent characteristics of the prosthesis can be an important limiting factor when considering the overall effectiveness of the closed-loop control. The presented test bench is an important instrument for investigating different aspects of human manual control with sensory feedback.

Gait adaptation to visual kinematic perturbations using a real-time closed-loop brain-computer interface to a virtual reality avatar

NASA Astrophysics Data System (ADS)

Phat Luu, Trieu; He, Yongtian; Brown, Samuel; Nakagome, Sho; Contreras-Vidal, Jose L.

2016-06-01

Objective. The control of human bipedal locomotion is of great interest to the field of lower-body brain-computer interfaces (BCIs) for gait rehabilitation. While the feasibility of closed-loop BCI systems for the control of a lower body exoskeleton has been recently shown, multi-day closed-loop neural decoding of human gait in a BCI virtual reality (BCI-VR) environment has yet to be demonstrated. BCI-VR systems provide valuable alternatives for movement rehabilitation when wearable robots are not desirable due to medical conditions, cost, accessibility, usability, or patient preferences. Approach. In this study, we propose a real-time closed-loop BCI that decodes lower limb joint angles from scalp electroencephalography (EEG) during treadmill walking to control a walking avatar in a virtual environment. Fluctuations in the amplitude of slow cortical potentials of EEG in the delta band (0.1-3 Hz) were used for prediction; thus, the EEG features correspond to time-domain amplitude modulated potentials in the delta band. Virtual kinematic perturbations resulting in asymmetric walking gait patterns of the avatar were also introduced to investigate gait adaptation using the closed-loop BCI-VR system over a period of eight days. Main results. Our results demonstrate the feasibility of using a closed-loop BCI to learn to control a walking avatar under normal and altered visuomotor perturbations, which involved cortical adaptations. The average decoding accuracies (Pearson’s r values) in real-time BCI across all subjects increased from (Hip: 0.18 ± 0.31 Knee: 0.23 ± 0.33 Ankle: 0.14 ± 0.22) on Day 1 to (Hip: 0.40 ± 0.24 Knee: 0.55 ± 0.20 Ankle: 0.29 ± 0.22) on Day 8. Significance. These findings have implications for the development of a real-time closed-loop EEG-based BCI-VR system for gait rehabilitation after stroke and for understanding cortical plasticity induced by a closed-loop BCI-VR system.

Tensile and Fatigue Testing and Material Hardening Model Development for 508 LAS Base Metal and 316 SS Similar Metal Weld under In-air and PWR Primary Loop Water Conditions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mohanty, Subhasish; Soppet, William; Majumdar, Saurin

This report provides an update on an assessment of environmentally assisted fatigue for light water reactor components under extended service conditions. This report is a deliverable in September 2015 under the work package for environmentally assisted fatigue under DOE’s Light Water Reactor Sustainability program. In an April 2015 report we presented a baseline mechanistic finite element model of a two-loop pressurized water reactor (PWR) for systemlevel heat transfer analysis and subsequent thermal-mechanical stress analysis and fatigue life estimation under reactor thermal-mechanical cycles. In the present report, we provide tensile and fatigue test data for 508 low-alloy steel (LAS) base metal,more » 508 LAS heat-affected zone metal in 508 LAS–316 stainless steel (SS) dissimilar metal welds, and 316 SS-316 SS similar metal welds. The test was conducted under different conditions such as in air at room temperature, in air at 300 oC, and under PWR primary loop water conditions. Data are provided on materials properties related to time-independent tensile tests and time-dependent cyclic tests, such as elastic modulus, elastic and offset strain yield limit stress, and linear and nonlinear kinematic hardening model parameters. The overall objective of this report is to provide guidance to estimate tensile/fatigue hardening parameters from test data. Also, the material models and parameters reported here can directly be used in commercially available finite element codes for fatigue and ratcheting evaluation of reactor components under in-air and PWR water conditions.« less

Systems-level feedback regulation of cell cycle transitions in Ostreococcus tauri.

PubMed

Kapuy, Orsolya; Vinod, P K; Bánhegyi, Gábor; Novák, Béla

2018-05-01

Ostreococcus tauri is the smallest free-living unicellular organism with one copy of each core cell cycle genes in its genome. There is a growing interest in this green algae due to its evolutionary origin. Since O. tauri is diverged early in the green lineage, relatively close to the ancestral eukaryotic cell, it might hold a key phylogenetic position in the eukaryotic tree of life. In this study, we focus on the regulatory network of its cell division cycle. We propose a mathematical modelling framework to integrate the existing knowledge of cell cycle network of O. tauri. We observe that feedback loop regulation of both G1/S and G2/M transitions in O. tauri is conserved, which can make the transition bistable. This is essential to make the transition irreversible as shown in other eukaryotic organisms. By performing sequence analysis, we also predict the presence of the Greatwall/PP2A pathway in the cell cycle of O. tauri. Since O. tauri cell cycle machinery is conserved, the exploration of the dynamical characteristic of the cell division cycle will help in further understanding the regulation of cell cycle in higher eukaryotes. Copyright © 2018 Elsevier Masson SAS. All rights reserved.

Principles of establishing material cycling with a high degree of closure in the experimental model of a BTLSS intended for a rated "fraction of a human"

NASA Astrophysics Data System (ADS)

Tikhomirov, Alexander A.; Ushakova, Sofya; Velichko, Vladimir; Tikhomirova, Natalia; Shikhov, Valentin; Trifonov, Sergey V.

2016-07-01

A promising way to develop future biotechnical life support systems (BTLSS) is to construct experimental models and establish the cycling intended for a fraction of a human. Being of relatively low cost, such models provide an opportunity to test effectively closed process that could be further transferred to the real BTLSS with humans. Researchers of the IBP SB RAS are developing an adequate BTLSS model with the loops closed to a high degree. To attain high closure of mass exchange processes, plants in the phototrophic compartment are cultivated under intensive lighting conditions, created by using modern LED irradiators of enhanced power, equipped with lens optics. The higher plant compartment has been renewed and broadened by including soybean plants, which improve the vegetable part of the human diet and make it more diverse. It is very important that the operation of the physicochemical installation for waste mineralization fully matches the composition of the atmosphere of plant growth chambers: the purified gaseous components of this installation enter the common atmosphere of the system, without causing any deviations from the norm in the gaseous composition. This proves the eco-friendliness of the developed physicochemical method of waste mineralization and shows that the gaseous components resulting from waste mineralization can be included in the system mass exchange. A system for including human respiration into the gas exchange of the BTLSS has been developed and tested; the associated gas exchange and water exchange dynamics have been analyzed. Results of the functioning of the experimental model of the BTLSS for several months are proposed for discussion in order to get insight into the formation of dynamic characteristics of cycling processes and factors determining them. The study was supported by the grant of the Russian Science Foundation (Project 14-14-00599) and carried out at the IBP SB RAS.

Solar Collector Mirror for Brayton Power System

NASA Image and Video Library

1966-09-21

NASA’s Lewis Research Center conducted extensive research programs in the 1960s and 1970s to develop systems that provide electrical power in space. One system, the Brayton cycle engine, converted solar thermal energy into electrical power. This system operated on a closed-loop Brayton thermodynamic cycle. The Brayton system relied on this large mirror to collect radiation from the sun. The mirror concentrated the Sun's rays on a heat storage receiver which warmed the Brayton system’s working fluid, a helium-xenon gas mixture. The heated fluid powered the system’s generator which produced power. In the mid-1960s Lewis researchers constructed this 30-foot diameter prototype of a parabolic solar mirror for the Brayton cycle system. The mirror had to be rigid, impervious to micrometeorite strikes, and lightweight. This mirror was comprised of twelve 1-inch thick magnesium plate sections that were coated with aluminum. The mirror could be compactly broken into its sections for launch.

Advanced Shock Position Control for Mode Transition in a Turbine Based Combined Cycle Engine Inlet Model

NASA Technical Reports Server (NTRS)

Csank, Jeffrey T.; Stueber, Thomas J.

2013-01-01

A dual flow-path inlet system is being tested to evaluate methodologies for a Turbine Based Combined Cycle (TBCC) propulsion system to perform a controlled inlet mode transition. Prior to experimental testing, simulation models are used to test, debug, and validate potential control algorithms. One simulation package being used for testing is the High Mach Transient Engine Cycle Code simulation, known as HiTECC. This paper discusses the closed loop control system, which utilizes a shock location sensor to improve inlet performance and operability. Even though the shock location feedback has a coarse resolution, the feedback allows for a reduction in steady state error and, in some cases, better performance than with previous proposed pressure ratio based methods. This paper demonstrates the design and benefit with the implementation of a proportional-integral controller, an H-Infinity based controller, and a disturbance observer based controller.

Antenna Linear-Quadratic-Gaussian (LQG) Ccontrollers: Properties, Limits of Performance, and Tuning

NASA Technical Reports Server (NTRS)

Gawronski, Wodek K.

2004-01-01

The LQG controllers significantly improve antenna tracking precision, but their tuning is a trial-and-error process. A control engineer has two tools to tune an LQG controller: the choice of coordinate system of the controller, and the selection of weights of the LQG performance index. The paper selects the coordinates of the open-loop model that simplify the shaping of the closed-loop performance. and analyzes the impact of thc weights on the antenna closed-loop bandwidth, disturbance rejection properties, and antenna acceleration. Finally, it presents the LQG controller tuning procedure that rationally shapes the closed-loop performance.

Solar heat transport fluids for solar energy collection systems: A collection of quarterly reports

NASA Technical Reports Server (NTRS)

1978-01-01

Noncorrosive fluid subsystem is being developed that is compatible with closed-loop solar heating and combined heating and hot water systems. The system is also to be compatible with both metallic and nonmetallic plumbing systems, and any combination of these. At least 100 gallons of each type of fluid recommended by the contractor will be delivered.

Analytical interferences of mercuric chloride preservative in environmental water samples: Determination of organic compounds isolated by continuous liquid-liquid extraction or closed-loop stripping

USGS Publications Warehouse

Foreman, W.T.; Zaugg, S.D.; Falres, L.M.; Werner, M.G.; Leiker, T.J.; Rogerson, P.F.

1992-01-01

Analytical interferences were observed during the determination of organic compounds in groundwater samples preserved with mercuric chloride. The nature of the interference was different depending on the analytical isolation technique employed. (1) Water samples extracted with dichloromethane by continuous liquid-liquid extraction (CLLE) and analyzed by gas chromatography/mass spectrometry revealed a broad HgCl2 'peak' eluting over a 3-5-min span which interfered with the determination of coeluting organic analytes. Substitution of CLLE for separatory funnel extraction in EPA method 508 also resulted in analytical interferences from the use of HgCl2 preservative. (2) Mercuric chloride was purged, along with organic contaminants, during closed-loop stripping (CLS) of groundwater samples and absorbed onto the activated charcoal trap. Competitive sorption of the HgCl2 by the trap appeared to contribute to the observed poor recoveries for spiked organic contaminants. The HgCl2 was not displaced from the charcoal with the dichloromethane elution solvent and required strong nitric acid to achieve rapid, complete displacement. Similar competitive sorption mechanisms might also occur in other purge and trap methods when this preservative is used.

A control system design approach for flexible spacecraft

NASA Technical Reports Server (NTRS)

Silverberg, L. M.

1985-01-01

A control system design approach for flexible spacecraft is presented. The control system design is carried out in two steps. The first step consists of determining the ideal control system in terms of a desirable dynamic performance. The second step consists of designing a control system using a limited number of actuators that possess a dynamic performance that is close to the ideal dynamic performance. The effects of using a limited number of actuators is that the actual closed-loop eigenvalues differ from the ideal closed-loop eigenvalues. A method is presented to approximate the actual closed-loop eigenvalues so that the calculation of the actual closed-loop eigenvalues can be avoided. Depending on the application, it also may be desirable to apply the control forces as impulses. The effect of digitizing the control to produce the appropriate impulses is also examined.

Geometrical criteria for characterizing open and closed states of WPD-loop in PTP1B

NASA Astrophysics Data System (ADS)

Shinde, Ranajit Nivrutti; Elizabeth Sobhia, M.

2012-06-01

Distinctive movement of WPD-loop occurs during the catalysis of phosphotyrosine by protein tyrosine phosphatase 1B (PTP1B). This loop is in the "open" state in apo-form whereas it is catalytically competent in the "closed" state. During the closure of this loop, unique hydrogen bond interactions are formed between different residues of the PTP1B. Present study examines such interactions from the available 118 crystal structures of PTP1B. It gives insights into the five novel hydrogen bonds essentially formed in the "closed" loop structures. Additionally, the study provides distance ranges between the atoms involved in the hydrogen bonds. This information can be used as a geometrical criterion in the characterization of conformational state of the WPD-loop especially in the molecular dynamics simulations.

78 FR 20176 - Credit for Renewable Electricity Production, Refined Coal Production, and Indian Coal Production...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-03

... electricity from closed-loop biomass, open-loop biomass, geothermal energy, solar energy, small irrigation..., geothermal energy, solar energy, small irrigation power, municipal solid waste, qualified hydropower... from the qualified energy resources of wind, closed-loop biomass, geothermal energy, and solar energy...

In-situ measurement of processing properties during fabrication in a production tool

NASA Technical Reports Server (NTRS)

Kranbuehl, D. E.; Haverty, P.; Hoff, M.; Loos, A. C.

1988-01-01

Progress is reported on the use of frequency-dependent electromagnetic measurements (FDEMs) as a single, convenient technique for continuous in situ monitoring of polyester cure during fabrication in a laboratory and manufacturing environment. Preliminary FDEM sensor and modeling work using the Loss-Springer model in order to develop an intelligent closed-loop, sensor-controlled cure process is described. FDEMs using impedance bridges in the Hz to MHz region is found to be ideal for automatically monitoring polyester processing properties continuously throughout the cure cycle.

A Satellite View of Global Water and Energy Cycling

NASA Astrophysics Data System (ADS)

Houser, P. R.

2012-12-01

The global water cycle describes liquid, solid and vapor water dynamics as it moves through the atmosphere, oceans and land. Life exists because of water, and civilization depends on adapting to the constraints imposed by water availability. The carbon, water and energy cycles are strongly interdependent - energy is moved through evaporation and condensation, and photosynthesis is closely related to transpiration. There are significant knowledge gaps about water storage, fluxes and dynamics - we currently do not really know how much water is stored in snowpacks, groundwater or reservoirs. The view from space offers a vision for water science advancement. This vision includes observation, understanding, and prediction advancements that will improve water management and to inform water-related infrastructure that planning to provide for human needs and to protect the natural environment. The water cycle science challenge is to deploy a series of coordinated earth observation satellites, and to integrate in situ and space-borne observations to quantify the key water-cycle state variables and fluxes. The accompanying societal challenge is to integrate this information along with water cycle physics, and ecosystems and societal considerations as a basis for enlightened water resource management and to protect life and property from effects of water cycle extremes. Better regional to global scale water-cycle observations and predictions need to be readily available to reduce loss of life and property caused by water-related hazards. To this end, the NASA Energy and Water cycle Study (NEWS) has been documenting the satellite view of the water cycle with a goal of enabling improved, observationally based, predictions of water and energy cycle consequences of Earth system variability and change. NEWS has fostered broad interdisciplinary collaborations to study experimental and operational satellite observations and has developed analysis tools for characterizing air/sea fluxes, ocean circulation, atmospheric states, radiative balances, land surface states, sub-surface hydrology, snow and ice. This presentation will feature an overview of recent progress towards this challenge, and lay out the plan for coordination with complementary international efforts.

Investigation of surface water behavior during glaze ice accretion

NASA Technical Reports Server (NTRS)

Hansman, R. John, Jr.; Turnock, Stephen R.

1988-01-01

Microvideo observations of glaze ice accretions on 1-in-diameter cylinders in a closed-loop refrigerated wind tunnel were obtained to study factors controlling the behavior of unfrozen surface water during glaze ice accretion. Three zones of surface water behavior were noted, each with a characteristic roughness. The effect of substrate thermal and roughness properties on ice accretions was also studied. The contact angle and hysteresis were found to increase sharply at temperatures just below 0 C, explaining the high resistance to motion of water beads observed on accreting glaze ice surfaces. Based on the results, a simple multizone modification to the current glaze ice accretion model is proposed.

Limit Cycle Bifurcations Near a Piecewise Smooth Generalized Homoclinic Loop with a Saddle-Fold Point

NASA Astrophysics Data System (ADS)

Liang, Feng; Wang, Dechang

In this paper, we suppose that a planar piecewise Hamiltonian system, with a straight line of separation, has a piecewise generalized homoclinic loop passing through a Saddle-Fold point, and assume that there exists a family of piecewise smooth periodic orbits near the loop. By studying the asymptotic expansion of the first order Melnikov function corresponding to the period annulus, we obtain the formulas of the first six coefficients in the expansion, based on which, we provide a lower bound for the maximal number of limit cycles bifurcated from the period annulus. As applications, two concrete systems are considered. Especially, the first one reveals that a quadratic piecewise Hamiltonian system can have five limit cycles near a generalized homoclinic loop under a quadratic piecewise smooth perturbation. Compared with the smooth case [Horozov & Iliev, 1994; Han et al., 1999], three more limit cycles are found.

Enabling Medical Device Interoperability for the Integrated Clinical Environment

DTIC Science & Technology

2016-02-01

Pajic M, Mangharam R, Sokolsky O, Arney D, Goldman JM, Lee I. Model-Driven Safety Analysis of Closed - Loop Medical Systems. IEEE Transactions on...Manigel J, Osborn D, Roellike T, Weininger S, Westenskow D, “Development of a Standard for Physiologic Closed Loop Controllers in Medical Devices...3 2010. 27. Arney D, Pajic M, Goldman JM, Lee I, Mangharam R, Sokolsky O, “Toward Patient Safety in Closed - Loop Medical Device Systems,” In

Closed Loop Control of Oxygen Delivery and Oxygen Generation

DTIC Science & Technology

2017-08-01

AFRL-SA-WP-SR-2017-0024 Closed Loop Control of Oxygen Delivery and Oxygen Generation Dr. Jay Johannigman1, Richard Branson1...for failing to comply with a collection of information if it does not display a currently valid OMB control number. PLEASE DO NOT RETURN YOUR FORM TO...TITLE AND SUBTITLE Closed Loop Control of Oxygen Delivery and Oxygen Generation 5a. CONTRACT NUMBER FA8650-10-2-6140 5b. GRANT NUMBER

Closed-loop model identification of cooperative manipulators holding deformable objects

NASA Astrophysics Data System (ADS)

Alkathiri, A. A.; Akmeliawati, R.; Azlan, N. Z.

2017-11-01

This paper presents system identification to obtain the closed-loop models of a couple of cooperative manipulators in a system, which function to hold deformable objects. The system works using the master-slave principle. In other words, one of the manipulators is position-controlled through encoder feedback, while a force sensor gives feedback to the other force-controlled manipulator. Using the closed-loop input and output data, the closed-loop models, which are useful for model-based control design, are estimated. The criteria for model validation are a 95% fit between the measured and simulated output of the estimated models and residual analysis. The results show that for both position and force control respectively, the fits are 95.73% and 95.88%.

Optimum design point for a closed-cycle OTEC system

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ikegami, Yasuyuki; Uehara, Haruo

1994-12-31

Performance analysis is performed for optimum design point of a closed-cycle Ocean Thermal Energy Conversion (OTEC) system. Calculations are made for an OTEC model plant with a gross power of 100 MW, which was designed by the optimization method proposed by Uehara and Ikegami for the design conditions of 21 C--29 C warm sea water temperature and 4 C cold sea water temperature. Ammonia is used as working fluid. Plate type evaporator and condenser are used as heat exchangers. The length of the cold sea water pipe is 1,000 m. This model plant is a floating-type OTEC plant. The objectivemore » function of optimum design point is defined as the total heat transfer area of heat exchangers per the annual net power.« less

Sub-Poissonian light and photocurrent shot-noise suppression in closed opto-electronic loop

NASA Technical Reports Server (NTRS)

Masalov, A. V.; Putilin, A. A.; Vasilyev, Michael V.

1994-01-01

We examine experimentally photocurrent noise reduction in the opto-electronic closed loop. Photocurrent noise density 12.5 dB below the shot-noise was observed. So large suppression was not reached in previous experiments and cannot be explained in terms of an ordinary sub-Poissonian light in the loop. We propose the concept of anticorrelation state for the description of light in the loop.

40 CFR 63.166 - Standards: Sampling connection systems.

Code of Federal Regulations, 2013 CFR

2013-07-01

... defined in 40 CFR part 261. (c) In-situ sampling systems and sampling systems without purges are exempt..., closed-loop, or closed-vent system, except as provided in § 63.162(b) of this subpart. Gases displaced...-purge, closed-loop, or closed-vent system as required in paragraph (a) of this section shall: (1) Return...

Heat Rejection Concepts for Lunar Fission Surface Power Applications

NASA Technical Reports Server (NTRS)

Siamidis, John

2006-01-01

This paper describes potential heat rejection design concepts for lunar surface Brayton power conversion systems. Brayton conversion systems are currently under study by NASA for surface power applications. Surface reactors may be used for the moon to power human outposts enabling extended stays and closed loop life support. The Brayton Heat Rejection System (HRS) must dissipate waste heat generated by the power conversion system due to inefficiencies in the thermal-to-electric conversion process. Space Brayton conversion system designs tend to optimize at efficiencies of about 20 to 25 percent with radiator temperatures in the 400 K to 600 K range. A notional HRS was developed for a 100 kWe-class Brayton power system that uses a pumped water heat transport loop coupled to a water heat pipe radiator. The radiator panels employ a tube and fin construction consisting of regularly-spaced circular heat pipes contained within two composite facesheets. The water heat pipes interface to the coolant through curved sections partially contained within the cooling loop. The paper evaluates various design parameters including radiator panel orientation, coolant flow path, and facesheet thickness. Parameters were varied to compare design options on the basis of H2O pump pressure rise and required power, heat pipe unit power and radial flux, radiator area, radiator panel areal mass, and overall HRS mass.

Arbuscular mycorrhizal fungi improve photosynthetic energy use efficiency and decrease foliar construction cost under recurrent water deficit in woody evergreen species.

PubMed

Barros, Vanessa; Frosi, Gabriella; Santos, Mariana; Ramos, Diego Gomes; Falcão, Hiram Marinho; Santos, Mauro Guida

2018-06-01

Plants suffer recurrent cycles of water deficit in semiarid regions and have several mechanisms to tolerate low water availability. Thus, arbuscular mycorrhizal fungi (AMF) can alleviate deleterious effects of stress. In this study, Cynophalla flexuosa plants, a woody evergreen species from semiarid, when associated with AMF were exposed to two consecutive cycles of water deficit. Leaf primary metabolism, specific leaf area (SLA), leaf construction cost (CC) and photosynthetic energy use efficiency (PEUE) were measured. The maximum stress occurred on seven days (cycle 1) and ten days (cycle 2) after suspending irrigation (photosynthesis close to zero). The rehydration was performed for three days after each maximum stress. In both cycles, plants submitted to water deficit showed reduced gas exchange and leaf relative water content. However, Drought + AMF plants had significantly larger leaf relative water content in cycle 2. At cycle 1, the SLA was larger in non-inoculated plants, while CC was higher in inoculated plants. At cycle 2, Drought + AMF treatment had lower CC and large SLA compared to control, and high PEUE compared to Drought plants. These responses suggest AMFs increase tolerance of C. flexuosa to recurrent water deficit, mainly in cycle 2, reducing the CC, promoting the improvement of SLA and PEUE, leading to higher photosynthetic area. Thus, our result emphasizes the importance of studies on recurrence of water deficit, a common condition in semiarid environments. Copyright © 2018 Elsevier Masson SAS. All rights reserved.

Development of an advanced spacecraft water and waste materials processing system

NASA Technical Reports Server (NTRS)

Murray, R. W.; Schelkopf, J. D.; Middleton, R. L.

1975-01-01

An Integrated Waste Management-Water System (WM-WS) which uses radioisotopes for thermal energy is described and results of its trial in a 4-man, 180 day simulated space mission are presented. It collects urine, feces, trash, and wash water in zero gravity, processes the wastes to a common evaporator, distills and catalytically purifies the water, and separates and incinerates the solid residues using little oxygen and no chemical additives or expendable filters. Technical details on all subsystems are given along with performance specifications. Data on recovered water and heat loss obtained in test trials are presented. The closed loop incinerator and other projects underway to increase system efficiency and capacity are discussed.

Enceladus and Europa: How Does Hydrothermal Activity Begin at the Surface?

NASA Technical Reports Server (NTRS)

Matson, D. L.; Castillo-Rogez, J. C.; Johnson, T. V.; Lunine, J. I.; Davies, A. G.

2011-01-01

The question of how the surface hydrothermal activity (e.g., eruptive plumes and heat flow) is initiated can be addressed within the frame-work of our "Perrier Ocean" model. This model delivers the necessary heat and chemicals to support the heat flow and plumes observed by Cassini in Enceladus' South Polar Region. The model employs closed-loop circulation of water from a sub-surface ocean. The ocean is the main reservoir of heat and chemicals, including dissolved gases. As ocean water moves up toward the surface, pressure is re-duced and gases exsolve forming bubbles. This bub-bly mixture is less dense than the icy crust and the buoyant ocean-water mixture rises toward the surface. Near the surface, heat and chemicals, including some volatiles, are delivered to the chambers in which plumes form and also to shallow reservoirs that keep the surface ice "warm". (Plume operations, per se, are as described by Schmidt et al. and Postberg et al. and are adopted by us.) After transferring heat, the water cools, bubbles contract and dissolve, and the mixture is now relatively dense. It descends through cracks in the crust and returns to the ocean. Once the closed-loop circulation has started it is self-sustaining. Loss of water via the erupting plumes is relatively negligible compared to the amount needed to maintain the heat flow.We note that the activity described herein for the the "Perrier-Ocean" model could, a priori, apply to all small icy bodies that sheltered an interior ocean at some point in their history.

"It Is Definitely a Game Changer": A Qualitative Study of Experiences with In-home Overnight Closed-Loop Technology Among Adults with Type 1 Diabetes.

PubMed

Hendrieckx, Christel; Poole, Lucinda A; Sharifi, Amin; Jayawardene, Dilshani; Loh, Margaret M; Horsburgh, Jodie C; Bach, Leon A; Colman, Peter G; Kumareswaran, Kavita; Jenkins, Alicia J; MacIsaac, Richard J; Ward, Glenn M; Grosman, Benyamin; Roy, Anirban; O'Neal, David N; Speight, Jane

2017-07-01

This qualitative study explored trial participants' experiences of four nights of in-home closed loop. Sixteen adults with type 1 diabetes, who completed a randomized crossover trial, were interviewed after four consecutive nights of closed-loop. Interviews were audio recorded, transcribed, and analyzed with a coding framework developed to identify the main themes. Participants had a mean age of 42 ± 10 years, nine were women; mean diabetes duration was 27 ± 7 years, and all were using insulin pumps. Overall, first impressions were positive. Participants found closed-loop easy to use and understand. Most experienced more stable overnight glucose levels, although for some these were similar to usual care or higher than they expected. Compared with their usual treatment, they noticed the proactive nature of the closed-loop, being able to predict trends and deliver micro amounts of insulin. Most reported technical glitches or inconveniences during one or more nights, such as transmission problems, problematic connectivity between devices, ongoing alarms despite addressing low glucose levels, and sensor inaccuracy. Remote monitoring by the trial team and their own hypoglycemic awareness contributed to feelings of trust and safety. Although rare, safety concerns were raised, related to feeling unsure whether the system would respond in time to falling glucose levels. This study provides relevant insights for implementation of closed-loop in the real world. For people with diabetes who are less familiar with technology, remote monitoring for the first few days may provide reassurance, strengthen their trust/skills, and make closed-loop an acceptable option for more people with type 1 diabetes.

The DOE water cycle pilot study.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Miller, N. L.; King, A. W.; Miller, M. A.

In 1999, the U.S. Global Change Research Program (USGCRP) formed a Water Cycle Study Group (Hornberger et al. 2001) to organize research efforts in regional hydrologic variability, the extent to which this variability is caused by human activity, and the influence of ecosystems. The USGCRP Water Cycle Study Group was followed by a U.S. Department of Energy (DOE) Water Cycle Research Plan (Department of Energy 2002) that outlined an approach toward improving seasonal-to-interannual hydroclimate predictability and closing a regional water budget. The DOE Water Cycle Research Plan identified key research areas, including a comprehensive long-term observational database to support modelmore » development, and to develop a better understanding of the relationship between the components of local water budgets and large scale processes. In response to this plan, a multilaboratory DOE Water Cycle Pilot Study (WCPS) demonstration project began with a focus on studying the water budget and its variability at multiple spatial scales. Previous studies have highlighted the need for continued efforts to observationally close a local water budget, develop a numerical model closure scheme, and further quantify the scales in which predictive accuracy are optimal. A concerted effort within the National Oceanic and Atmospheric Administration (NOAA)-funded Global Energy and Water Cycle Experiment (GEWEX) Continental-scale International Project (GCIP) put forth a strategy to understand various hydrometeorological processes and phenomena with an aim toward closing the water and energy budgets of regional watersheds (Lawford 1999, 2001). The GCIP focus on such regional budgets includes the measurement of all components and reduction of the error in the budgets to near zero. To approach this goal, quantification of the uncertainties in both measurements and modeling is required. Model uncertainties within regional climate models continue to be evaluated within the Program to Intercompare Regional Climate Simulations (Takle et al. 1999), and model uncertainties within land surface models are being evaluated within the Program to Intercompare Land Surface Schemes (e.g., Henderson-Sellers 1993; Wood et al. 1998; Lohmann et al. 1998). In the context of understanding the water budget at watershed scales, the following two research questions that highlight DOE's unique water isotope analysis and high-performance modeling capabilities were posed as the foci of this pilot study: (1) Can the predictability of the regional water budget be improved using high-resolution model simulations that are constrained and validated with new hydrospheric water measurements? (2) Can water isotopic tracers be used to segregate different pathways through the water cycle and predict a change in regional climate patterns? To address these questions, numerical studies using regional atmospheric-land surface models and multiscale land surface hydrologic models were generated and, to the extent possible, the results were evaluated with observations. While the number of potential processes that may be important in the local water budget is large, several key processes were examined in detail. Most importantly, a concerted effort was made to understand water cycle processes and feedbacks at the land surface-atmosphere interface at spatial scales ranging from 30 m to hundreds of kilometers. A simple expression for the land surface water budget at the watershed scale is expressed as {Delta}S = P + G{sub in} - ET - Q - G{sub out}, where {Delta}S is the change in water storage, P is precipitation, ET is evapotranspiration, Q is streamflow, G{sub in} is groundwater entering the watershed, and G{sub out} is groundwater leaving the watershed, per unit time. The WCPS project identified data gaps and necessary model improvements that will lead to a more accurate representation of the terms in Eq. (1). Table 1 summarizes the components of this water cycle pilot study and the respective participants. The following section provides a description of the surface observation and modeling sites. This is followed by a section on model analyses, and then the summary and concluding remarks.« less

AQUILA Remotely Piloted Vehicle System Technology Demonstrator (RPV-STD) Program. Volume I. System Description and Capabilities

DTIC Science & Technology

1979-04-01

tools, simplification of equipment interfaces involved in manual operations to provide simple system preparation, closing flight control inner loops ...alti- tude, and heading rate. The closed loops operate in three primary modes: cruise, dead reckoning, and approach. The aircraft is stabilized by...onboard closed loops , so the operator is not required to maintain hands-on operation to keep it in the air. The operator is able to command airspeed

Plastic flexible films waste management - A state of art review.

PubMed

Horodytska, O; Valdés, F J; Fullana, A

2018-04-21

Plastic flexible films are increasingly used in many applications due to their lightness and versatility. In 2014, the amount of plastic films represented 34% of total plastic packaging produced in UK. The flexible film waste generation rises according to the increase in number of applications. Currently, in developed countries, about 50% of plastics in domestic waste are films. Moreover, about 615,000 tonnes of agricultural flexible waste are generated in the EU every year. A review of plastic films recycling has been conducted in order to detect the shortcomings and establish guidelines for future research. This paper reviews plastic films waste management technologies from two different sources: post-industrial and post-consumer. Clean and homogeneous post-industrial waste is recycled through closed-loop or open-loop mechanical processes. The main differences between these methods are the quality and the application of the recycled materials. Further research should be focused on closing the loops to obtain the highest environmental benefits of recycling. This could be accomplished through minimizing the material degradation during mechanical processes. Regarding post-consumer waste, flexible films from agricultural and packaging sectors have been assessed. The agricultural films and commercial and industrial flexible packaging are recycled through open-loop mechanical recycling due to existing selective waste collection routes. Nevertheless, the contamination from the use phase adversely affects the quality of recycled plastics. Therefore, upgrading of current washing lines is required. On the other hand, household flexible packaging shows the lowest recycling rates mainly because of inefficient sorting technologies. Delamination and compatibilization methods should be further developed to ensure the recycling of multilayer films. Finally, Life Cycle Assessment (LCA) studies on waste management have been reviewed. A lack of thorough LCA on plastic films waste management systems was identified. Copyright © 2018 Elsevier Ltd. All rights reserved.

Closed loop problems in biomechanics. Part II--an optimization approach.

PubMed

Vaughan, C L; Hay, J G; Andrews, J G

1982-01-01

A closed loop problem in biomechanics may be defined as a problem in which there are one or more closed loops formed by the human body in contact with itself or with an external system. Under certain conditions the problem is indeterminate--the unknown forces and torques outnumber the equations. Force transducing devices, which would help solve this problem, have serious drawbacks, and existing methods are inaccurate and non-general. The purposes of the present paper are (1) to develop a general procedure for solving closed loop problems; (2) to illustrate the application of the procedure; and (3) to examine the validity of the procedure. A mathematical optimization approach is applied to the solution of three different closed loop problems--walking up stairs, vertical jumping and cartwheeling. The following conclusions are drawn: (1) the method described is reasonably successful for predicting horizontal and vertical reaction forces at the distal segments although problems exist for predicting the points of application of these forces; (2) the results provide some support for the notion that the human neuromuscular mechanism attempts to minimize the joint torques and thus, to a certain degree, the amount of muscular effort; (3) in the validation procedure it is desirable to have a force device for each of the distal segments in contact with a fixed external system; and (4) the method is sufficiently general to be applied to all classes of closed loop problems.

Closed-loop for type 1 diabetes - an introduction and appraisal for the generalist.

PubMed

Bally, Lia; Thabit, Hood; Hovorka, Roman

2017-01-23

Rapid progress over the past decade has been made with the development of the 'Artificial Pancreas', also known as the closed-loop system, which emulates the feedback glucose-responsive functionality of the pancreatic beta cell. The recent FDA approval of the first hybrid closed-loop system makes the Artificial Pancreas a realistic therapeutic option for people with type 1 diabetes. In anticipation of its advent into clinical care, we provide a primer and appraisal of this novel therapeutic approach in type 1 diabetes for healthcare professionals and non-specialists in the field. Randomised clinical studies in outpatient and home settings have shown improved glycaemic outcomes, reduced risk of hypoglycaemia and positive user attitudes. User input and interaction with existing closed-loop systems, however, are still required. Therefore, management of user expectations, as well as training and support by healthcare providers are key to ensure optimal uptake, satisfaction and acceptance of the technology. An overview of closed-loop technology and its clinical implications are discussed, complemented by our extensive hands-on experience with closed-loop system use during free daily living. The introduction of the artificial pancreas into clinical practice represents a milestone towards the goal of improving the care of people with type 1 diabetes. There remains a need to understand the impact of user interaction with the technology, and its implication on current diabetes management and care.

The effects of spaceflight on open-loop and closed-loop postural control mechanisms: human neurovestibular studies on SLS-2

NASA Technical Reports Server (NTRS)

Collins, J. J.; De Luca, C. J.; Pavlik, A. E.; Roy, S. H.; Emley, M. S.; Young, L. R. (Principal Investigator)

1995-01-01

Stabilogram-diffusion analysis was used to examine how prolonged periods in microgravity affect the open-loop and closed-loop postural control mechanisms. It was hypothesized that following spaceflight: (1) the effective stochastic activity of the open-loop postural control schemes in astronauts is increased; (2) the effective stochastic activity and uncorrelated behavior, respectively, of the closed-loop postural control mechanisms in astronauts are increased; and (3) astronauts utilized open-loop postural controls schemes for shorter time intervals and smaller displacements. Four crew members and two alternates from the 14-day Spacelab Life Sciences 2 Mission were included in the study. Each subject was tested under eyes-open, quiet-standing conditions on multiple preflight and postflight days. The subjects' center-of-pressure trajectories were measured with a force platform and analyzed according to stabilogram-diffusion analysis. It was found that the effective stochastic activity of the open-loop postural control schemes in three of the four crew members was increased following spaceflight. This result is interpreted as an indication that there may be in-flight adaptations to higher-level descending postural control pathways, e.g., a postflight increase in the tonic activation of postural muscles. This change may also be the consequence of a compensatory (e.g., "stiffening") postural control strategy that is adopted by astronauts to account for general feeling of postflight unsteadiness. The crew members, as a group, did not exhibit any consistent preflight/postflight differences in the steady-state behavior of their closed-loop postural control mechanisms or in the functional interaction of their open-loop and closed-loop postural control mechanisms. These results are interpreted as indications that although there may be in-flight adaptations to the vestibular system and/or proprioceptive system, input from the visual system can compensate for such changes during undisturbed stance.

Architecture and inherent robustness of a bacterial cell-cycle control system.

PubMed

Shen, Xiling; Collier, Justine; Dill, David; Shapiro, Lucy; Horowitz, Mark; McAdams, Harley H

2008-08-12

A closed-loop control system drives progression of the coupled stalked and swarmer cell cycles of the bacterium Caulobacter crescentus in a near-mechanical step-like fashion. The cell-cycle control has a cyclical genetic circuit composed of four regulatory proteins with tight coupling to processive chromosome replication and cell division subsystems. We report a hybrid simulation of the coupled cell-cycle control system, including asymmetric cell division and responses to external starvation signals, that replicates mRNA and protein concentration patterns and is consistent with observed mutant phenotypes. An asynchronous sequential digital circuit model equivalent to the validated simulation model was created. Formal model-checking analysis of the digital circuit showed that the cell-cycle control is robust to intrinsic stochastic variations in reaction rates and nutrient supply, and that it reliably stops and restarts to accommodate nutrient starvation. Model checking also showed that mechanisms involving methylation-state changes in regulatory promoter regions during DNA replication increase the robustness of the cell-cycle control. The hybrid cell-cycle simulation implementation is inherently extensible and provides a promising approach for development of whole-cell behavioral models that can replicate the observed functionality of the cell and its responses to changing environmental conditions.

Operation and maintenance of the SOL-DANCE building solar system. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1980-07-29

The Sol-Dance building solar heating system consists of 136 flat plate solar collectors divided evenly into two separate building systems, each providing its total output to a common thermal storage tank. An aromatic base transformer oil is circulated through a closed loop consisting of the collectors and a heat exchanger. Water from the thermal storage tank is passed through the same heat exchanger where heat from the oil is given up to the thermal storage. Back-up heat is provided by air source heat pumps. Heat is transferred from the thermal storage to the living space by liquid-to-air coils in themore » distribution ducts. Separate domestic hot water systems are provided for each building. The system consists of 2 flat plate collectors with a single 66 gallon storage tank with oil circulated in a closed loop through an external tube and shell heat exchanger. Some problems encountered and lessons learned during the project construction are listed as well as beneficial aspects and a project description. As-built drawings are provided as well as system photographs. An acceptance test plan is provided that checks the collection, thermal storage, and space and water heating subsystems and the total system installation. Predicted performance data are tabulated. Details are discussed regarding operation, maintenance, and repair, and manufacturers data are provided. (LEW)« less

Inverse spin Hall effect in a closed loop circuit

DOE Office of Scientific and Technical Information (OSTI.GOV)

Omori, Y.; Auvray, F.; Wakamura, T.

We present measurements of inverse spin Hall effects (ISHEs), in which the conversion of a spin current into a charge current via the ISHE is detected not as a voltage in a standard open circuit but directly as the charge current generated in a closed loop. The method is applied to the ISHEs of Bi-doped Cu and Pt. The derived expression of ISHE for the loop structure can relate the charge current flowing into the loop to the spin Hall angle of the SHE material and the resistance of the loop.

Carbon cycling in a zero-discharge mariculture system.

PubMed

Schneider, Kenneth; Sher, Yonatan; Erez, Jonathan; van Rijn, Jaap

2011-03-01

Interest in mariculture systems will rise in the near future due to the decreased ability of the ocean to supply the increasing demand for seafood. We present a trace study using stable carbon and nitrogen isotopes and chemical profiles of a zero-discharge mariculture system stocked with the gilthead seabream (Sparus aurata). Water quality maintenance in the system is based on two biofiltration steps. Firstly, an aerobic treatment step comprising a trickling filter in which ammonia is oxidized to nitrate. Secondly, an anaerobic step comprised of a digestion basin and a fluidized bed reactor where excess organic matter and nitrate are removed. Dissolved inorganic carbon and alkalinity values were higher in the anaerobic loop than in the aerobic loop, in agreement with the main biological processes taking place in the two treatment steps. The δ13C of the dissolved inorganic carbon (δ13C(DIC)) was depleted in 13C in the anaerobic loop as compared to the aerobic loop by 2.5-3‰. This is in agreement with the higher dissolved inorganic carbon concentrations in the anaerobic loop and the low water retention time and the chemolithotrophic activity of the aerobic loop. The δ13C and δ15N of organic matter in the mariculture system indicated that fish fed solely on feed pellets. Compared to feed pellets and particulate organic matter, the sludge in the digestion basin was enriched in 15N while δ13C was not significantly different. This latter finding points to an intensive microbial degradation of the organic matter taking place in the anaerobic treatment step of the system. Copyright © 2011 Elsevier Ltd. All rights reserved.

Insulin delivery and nocturnal glucose control in children and adolescents with type 1 diabetes.

PubMed

Tauschmann, Martin; Hovorka, Roman

2017-12-01

Nocturnal glucose control remains challenging in children and adolescents with type 1 diabetes due to highly variable overnight insulin requirements. The issue may be addressed by glucose responsive insulin delivery based on real-time continuous glucose measurements. Areas covered: This review outlines recent developments of glucose responsive insulin delivery systems from a paediatric perspective. We cover threshold-based suspend application, predictive low glucose suspend, and more advanced single hormone and dual-hormone closed-loop systems. Approaches are evaluated in relation to nocturnal glucose control particularly during outpatient randomised controlled trials. Expert opinion: Significant progress translating research from controlled clinical centre settings to free-living unsupervised home studies have been achieved over the past decade. Nocturnal glycaemic control can be improved whilst reducing the risk of hypoglycaemia with closed-loop systems. Following the US regulatory approval of the first hybrid closed-loop system in non-paediatric population, large multinational closed-loop clinical trials and pivotal studies including paediatric populations are underway or in preparation to facilitate the use of closed-loop systems in clinical practice.

Simulation of cortico-basal ganglia oscillations and their suppression by closed loop deep brain stimulation.

PubMed

Grant, Peadar F; Lowery, Madeleine M

2013-07-01

A new model of deep brain stimulation (DBS) is presented that integrates volume conduction effects with a neural model of pathological beta-band oscillations in the cortico-basal ganglia network. The model is used to test the clinical hypothesis that closed-loop control of the amplitude of DBS may be possible, based on the average rectified value of beta-band oscillations in the local field potential. Simulation of closed-loop high-frequency DBS was shown to yield energy savings, with the magnitude of the energy saved dependent on the strength of coupling between the subthalamic nucleus and the remainder of the cortico-basal ganglia network. When closed-loop DBS was applied to a strongly coupled cortico-basal ganglia network, the stimulation energy delivered over a 480 s period was reduced by up to 42%. Greater energy reductions were observed for weakly coupled networks, as the stimulation amplitude reduced to zero once the initial desynchronization had occurred. The results provide support for the application of closed-loop high-frequency DBS based on electrophysiological biomarkers.

Effect of ambient pressure variation on closed loop gas system for India based Neutrino Observatory (INO)

NASA Astrophysics Data System (ADS)

Satyanarayana, B.; Majumder, G.; Mondal, N. K.; Kalmani, S. D.; Shinde, R. R.; Joshi, A.

2014-10-01

Pilot unit of a closed loop gas mixing and distribution system for the INO project was designed and is being operated with 1.8meters × 1.9meters RPCs for about two years. A number of studies on controlling the flow and optimisation of the gas mixture through the RPC stack were carried out during this period. The gas system essentially measures and attempts to maintain absolute pressure inside the RPC gas volume. During typical Mumbai monsoon seasons, the barometric pressure changes rather rapidly, due to which the gas system fails to maintain the set differential pressure between the ambience and the RPC gas volume. As the safety bubblers on the RPC gas input lines are set to work on fixed pressure differentials, the ambient pressure changes lead to either venting out and thus wasting gas through safety bubblers or over pressuring the RPCs gas volume and thus degrading its performance. The above problem also leads to gas mixture contamination through minute leaks in gas gap. The problem stated above was solved by including the ambient barometric pressure as an input parameter in the closed loop. Using this, it is now possible to maintain any set differential pressure between the ambience and RPC gas volumes between 0 to 20mm of water column, thus always ensuring a positive pressure inside the RPC gas volume with respect to the ambience. This has resulted in improved performance of the gas system by maintaining the constant gas flow and reducing the gas toping up frequency. In this paper, we will highlight the design features and improvements of the closed loop gas system. We will present some of the performance studies and considerations for scaling up the system to be used with the engineering module and then followed by Iron Calorimeter detector (ICAL), which is designed to deploy about 30,000 RPCs of 1.8meters × 1.9 meters in area.

Guided Inquiry Learning With Sea Water Battery Project

NASA Astrophysics Data System (ADS)

Mashudi, A.

2017-02-01

Science learning process is expected to produce valuable product, innovative and real learning environment, and provide memorable learning experience. That orientation can be contained in Inquiry Based Learning. SMP N 4 Juwana is located close to the beach. That’s why, Sea Water Battery Project is very suitable to be applied in learning activity as an effort to fulfill the renewable energy based on local wisdom. This study aims to increase interest, activity and achievement of students. Learning implementation stage, namely : Constructing Sea Water Battery project, observation, group presentations, and feedback. Sea Water Battery is renewable energy battery from materials easily found around the learner. The materials used are copper plate as the anode, zinc plate as the cathode and sea water as the electrolyte. Average score of students Interest on the first cycle 76, while on the second cycle 85. Average score of students Activity on the first cycle 76 and on the second cycle 86. Average score of students achievement on the first cycle 75, while on the second cycle 84. This learning process gave nurturant effect for students to keep innovating and construct engineering technology for the future.

The design of components for an advanced Rankine cycle test facility.

NASA Technical Reports Server (NTRS)

Bond, J. A.

1972-01-01

The design of a facility for testing components of an advanced Rankine cycle power system is summarized. The facility is a three-loop system in which lithium, potassium and NaK-78 are the working fluids of the primary, secondary and heat-rejection loops, respectively. Design bases and performance predictions for the major loop components, including the lithium heater and the potassium boiler, condenser and preheater, are outlined.

Estrous cycle and food availability affect feeding induced by amygdala 5-HT receptor blockade.

PubMed

Parker, Graham C; Bishop, Christopher; Coscina, Donald V

2002-04-01

We have recently reported that bilateral infusions of the 5-HT receptor antagonist metergoline (MET) into the posterior basolateral amygdala (pBLA) elicit feeding in female rats tested at mid-light cycle. The present study was performed to determine whether (1) testing at two different phases of the estrous cycle, and/or (2) the palatability of the food might modify this effect. Subjects were 18 adult females with bilateral pBLA cannulae. Following familiarization with Froot Loops cereal, a within-subjects design tested all animals for 1- and 2-h food intake under 2 Drug (0.3 nmol MET vs. Vehicle), 2 Estrous Cycle (diestrus vs. estrus) and 2 Food (lab chow vs. Froot Loops) conditions. Rats weighed more at diestrus than at proestrus (P<.05) or estrus (P<.005). Multivariate analyses of variance (MANOVAs) revealed a preference for Froot Loops over lab chow (P<.0001). MET increased feeding regardless of food type (P<.0001). Rats ate more Froot Loops (P<.01), but not lab chow, at diestrus vs. estrus. A three-way interaction (P<.05) showed rats ate more during the first hour in estrus than in diestrus to lab chow but not Froot Loops. These data suggest pBLA MET differentially affects feeding over the estrous cycle depending on the palatability of food available.

Lidar-based wake tracking for closed-loop wind farm control

NASA Astrophysics Data System (ADS)

Raach, Steffen; Schlipf, David; Cheng, Po Wen

2016-09-01

This work presents two advancements towards closed-loop wake redirecting of a wind turbine. First, a model-based estimation approach is presented which uses a nacelle-based lidar system facing downwind to obtain information about the wake. A reduced order wake model is described which is then used in the estimation to track the wake. The tracking is demonstrated with lidar measurement data from an offshore campaign and with simulated lidar data from a SOWFA simulation. Second, a controller for closed-loop wake steering is presented. It uses the wake tracking information to set the yaw actuator of the wind turbine to redirect the wake to a desired position. Altogether, this paper aims to present the concept of closed-loop wake redirecting and gives a possible solution to it.

Closed-Loop and Activity-Guided Optogenetic Control

PubMed Central

Grosenick, Logan; Marshel, James H.; Deisseroth, Karl

2016-01-01

Advances in optical manipulation and observation of neural activity have set the stage for widespread implementation of closed-loop and activity-guided optical control of neural circuit dynamics. Closing the loop optogenetically (i.e., basing optogenetic stimulation on simultaneously observed dynamics in a principled way) is a powerful strategy for causal investigation of neural circuitry. In particular, observing and feeding back the effects of circuit interventions on physiologically relevant timescales is valuable for directly testing whether inferred models of dynamics, connectivity, and causation are accurate in vivo. Here we highlight technical and theoretical foundations as well as recent advances and opportunities in this area, and we review in detail the known caveats and limitations of optogenetic experimentation in the context of addressing these challenges with closed-loop optogenetic control in behaving animals. PMID:25856490

Sheet Membrane Spacesuit Water Membrane Evaporator

NASA Technical Reports Server (NTRS)

Bue, Grant; Trevino, Luis; Zapata, Felipe; Dillion, Paul; Castillo, Juan; Vonau, Walter; Wilkes, Robert; Vogel, Matthew; Frodge, Curtis

2013-01-01

A document describes a sheet membrane spacesuit water membrane evaporator (SWME), which allows for the use of one common water tank that can supply cooling water to the astronaut and to the evaporator. Test data showed that heat rejection performance dropped only 6 percent after being subjected to highly contaminated water. It also exhibited robustness with respect to freezing and Martian atmospheric simulation testing. Water was allowed to freeze in the water channels during testing that simulated a water loop failure and vapor backpressure valve failure. Upon closing the backpressure valve and energizing the pump, the ice eventually thawed and water began to flow with no apparent damage to the sheet membrane. The membrane evaporator also serves to de-gas the water loop from entrained gases, thereby eliminating the need for special degassing equipment such as is needed by the current spacesuit system. As water flows through the three annular water channels, water evaporates with the vapor flowing across the hydrophobic, porous sheet membrane to the vacuum side of the membrane. The rate at which water evaporates, and therefore, the rate at which the flowing water is cooled, is a function of the difference between the water saturation pressure on the water side of the membrane, and the pressure on the vacuum side of the membrane. The primary theory is that the hydrophobic sheet membrane retains water, but permits vapor pass-through when the vapor side pressure is less than the water saturation pressure. This results in evaporative cooling of the remaining water.

Study of the Open Loop and Closed Loop Oscillator Techniques

DOE Office of Scientific and Technical Information (OSTI.GOV)

Imel, George R.; Baker, Benjamin; Riley, Tony

This report presents the progress and completion of a five-year study undertaken at Idaho State University of the measurement of very small worth reactivity samples comparing open and closed loop oscillator techniques.The study conclusively demonstrated the equivalency of the two techniques with regard to uncertainties in reactivity values, i.e., limited by reactor noise. As those results are thoroughly documented in recent publications, in this report we will concentrate on the support work that was necessary. For example, we describe in some detail the construction and calibration of a pilot rod for the closed loop system. We discuss the campaign tomore » measure the required reactor parameters necessary for inverse-kinetics. Finally, we briefly discuss the transfer of the open loop technique to other reactor systems.« less

Study of the open loop and closed loop oscillator techniques

DOE Office of Scientific and Technical Information (OSTI.GOV)

Baker, Benjamin; Riley, Tony; Langbehn, Adam

This paper presents some aspects of a five year study undertaken at Idaho State University of the measurement of very small worth reactivity samples comparing open and closed loop oscillator techniques. The study conclusively demonstrated the equivalency of the two techniques with regard to uncertainties in reactivity values, i.e., limited by reactor noise. As those results are thoroughly documented in recent publications, in this paper we will concentrate on the support work that was necessary. For example, we describe in some detail the construction and calibration of a pilot rod for the closed loop system. We discuss the campaign tomore » measure the required reactor parameters necessary for inverse-kinetics. Finally, we briefly discuss the transfer of the open loop technique to other reactor systems. (authors)« less

Methods and apparatus for broadband frequency comb stabilization

DOEpatents

Cox, Jonathan A; Kaertner, Franz X

2015-03-17

Feedback loops can be used to shift and stabilize the carrier-envelope phase of a frequency comb from a mode-locked fibers laser or other optical source. Compared to other frequency shifting and stabilization techniques, feedback-based techniques provide a wideband closed-loop servo bandwidth without optical filtering, beam pointing errors, or group velocity dispersion. It also enables phase locking to a stable reference, such as a Ti:Sapphire laser, continuous-wave microwave or optical source, or self-referencing interferometer, e.g., to within 200 mrad rms from DC to 5 MHz. In addition, stabilized frequency combs can be coherently combined with other stable signals, including other stabilized frequency combs, to synthesize optical pulse trains with pulse durations of as little as a single optical cycle. Such a coherent combination can be achieved via orthogonal control, using balanced optical cross-correlation for timing stabilization and balanced homodyne detection for phase stabilization.

Open-cycle magnetohydrodynamic power plant based upon direct-contact closed-loop high-temperature heat exchanger

DOEpatents

Berry, G.F.; Minkov, V.; Petrick, M.

1981-11-02

A magnetohydrodynamic (MHD) power generating system is described in which ionized combustion gases with slag and seed are discharged from an MHD combustor and pressurized high temperature inlet air is introduced into the combustor for supporting fuel combustion at high temperatures necessary to ionize the combustion gases, and including a heat exchanger in the form of a continuous loop with a circulating heat transfer liquid such as copper oxide. The heat exchanger has an upper horizontal channel for providing direct contact between the heat transfer liquid and the combustion gases to cool the gases and condense the slag which thereupon floats on the heat transfer liquid and can be removed from the channel, and a lower horizontal channel for providing direct contact between the heat transfer liquid and pressurized air for preheating the inlet air. The system further includes a seed separator downstream of the heat exchanger.

Open-cycle magnetohydrodynamic power plant based upon direct-contact closed-loop high-temperature heat exchanger

DOEpatents

Berry, Gregory F.; Minkov, Vladimir; Petrick, Michael

1988-01-05

A magnetohydrodynamic (MHD) power generating system in which ionized combustion gases with slag and seed are discharged from an MHD combustor and pressurized high temperature inlet air is introduced into the combustor for supporting fuel combustion at high temperatures necessary to ionize the combustion gases, and including a heat exchanger in the form of a continuous loop with a circulating heat transfer liquid such as copper oxide. The heat exchanger has an upper horizontal channel for providing direct contact between the heat transfer liquid and the combustion gases to cool the gases and condense the slag which thereupon floats on the heat transfer liquid and can be removed from the channel, and a lower horizontal channel for providing direct contact between the heat transfer liquid and pressurized air for preheating the inlet air. The system further includes a seed separator downstream of the heat exchanger.

Open-cycle magnetohydrodynamic power plant based upon direct-contact closed-loop high-temperature heat exchanger

DOEpatents

Berry, Gregory F.; Minkov, Vladimir; Petrick, Michael

1988-01-01

A magnetohydrodynamic (MHD) power generating system in which ionized combustion gases with slag and seed are discharged from an MHD combustor and pressurized high temperature inlet air is introduced into the combustor for supporting fuel combustion at high temperatures necessary to ionize the combustion gases, and including a heat exchanger in the form of a continuous loop with a circulating heat transfer liquid such as copper oxide. The heat exchanger has an upper horizontal channel for providing direct contact between the heat transfer liquid and the combustion gases to cool the gases and condense the slag which thereupon floats on the heat transfer liquid and can be removed from the channel, and a lower horizontal channel for providing direct contact between the heat transfer liquid and pressurized air for preheating the inlet air. The system further includes a seed separator downstream of the heat exchanger.

The water cycle in closed ecological systems: Perspectives from the Biosphere 2 and Laboratory Biosphere systems

NASA Astrophysics Data System (ADS)

Nelson, Mark; Dempster, W. F.; Allen, J. P.

2009-12-01

To achieve sustainable, healthy closed ecological systems requires solutions to challenges of closing the water cycle - recycling wastewater/irrigation water/soil medium leachate and evaporated water and supplying water of required quality as needed for different needs within the facility. Engineering Biosphere 2, the first multi-biome closed ecological system within a total airtight footprint of 12,700 m 2 with a combined volume of 200,000 m 3 with a total water capacity of some 6 × 10 6 L of water was especially challenging because it included human inhabitants, their agricultural and technical systems, as well as five analogue ecosystems ranging from rainforest to desert, freshwater ecologies to saltwater systems like mangrove and mini-ocean coral reef ecosystems. By contrast, the Laboratory Biosphere - a small (40 m 3 volume) soil-based plant growth facility with a footprint of 15 m 2 - is a very simplified system, but with similar challenges re salinity management and provision of water quality suitable for plant growth. In Biosphere 2, water needs included supplying potable water for people and domestic animals, irrigation water for a wide variety of food crops, and recycling and recovering soil nutrients from wastewater. In the wilderness biomes, providing adequately low salinity freshwater terrestrial ecosystems and maintaining appropriate salinity and pH in aquatic/marine ecosystems were challenges. The largest reservoirs in Biosphere 2 were the ocean/marsh with some 4 × 10 6 L, soil with 1 to 2 × 10 6 l, primary storage tank with 0 to 8 × 10 5 L and storage tanks for condensate and soil leachate collection and mixing tanks with a capacity of 1.6 × 10 5 L to supply irrigation for farm and wilderness ecosystems. Other reservoirs were far smaller - humidity in the atmosphere (2 × 10 3 L), streams in the rainforest and savannah, and seasonal pools in the desert were orders of magnitude smaller (8 × 10 4 L). Key technologies included condensation from humidity in the air handlers and from the glass space frame to produce high quality freshwater, wastewater treatment with constructed wetlands and desalination through reverse osmosis and flash evaporation were key to recycling water with appropriate quality throughout the Biosphere 2 facility. Wastewater from all human uses and the domestic animals in Biosphere 2 was treated and recycled through a series of constructed wetlands, which had hydraulic loading of 0.9-1.1 m 3 day -1 (240-290 gal d -1). Plant production in the wetland treatment system produced 1210 kg dry weight of emergent and floating aquatic plant wetland which was used as fodder for the domestic animals while remaining nutrients/water was reused as part of the agricultural irrigation supply. There were pools of water with recycling times of days to weeks and others with far longer cycling times within Biosphere 2. By contrast, the Laboratory Biosphere with a total water reservoir of less than 500 L has far quicker cycling rapidity: for example, atmospheric residence time for water vapor was 5-20 min in the Laboratory Biosphere vs. 1-4 h in Biosphere 2, as compared with 9 days in the Earth's biosphere. Just as in Biosphere 2, humidity in the Laboratory Biosphere amounts to a very small reservoir of water. The amount of water passing through the air in the course of a 12-h operational day is two orders of magnitude greater than the amount stored in the air. Thus, evaporation and condensation collection are vital parts of the recycle system just as in Biosphere 2. The water cycle and sustainable water recycling in closed ecological systems presents problems requiring further research - such as how to control buildup of salinity in materially closed ecosystems and effective ways to retain nutrients in optimal quantity and useable form for plant growth. These issues are common to all closed ecological systems of whatever size, including planet Earth's biosphere and are relevant to a global environment facing increasing water shortages while maintaining water quality for human and ecosystem health. Modular biospheres offer a test bed where technical methods of resolving these problems can be tested for feasibility.

The effects of recycling loops in food waste management in Japan: based on the environmental and economic evaluation of food recycling.

PubMed

Takata, Miki; Fukushima, Kazuyo; Kino-Kimata, Noriko; Nagao, Norio; Niwa, Chiaki; Toda, Tatsuki

2012-08-15

In Japan, a revised Food Recycling Law went into effect in 2007 to promote a "recycling loop" that requires food industries to purchase farm products that are grown using food waste-derived compost/animal feed. To realize and expand food recycling, it is necessary to evaluate how the recycling facilities work in the recycling loop. The purpose of this study is to assess the environmental and economic efficiency of the food recycling facilities that are involved in the recycling loop, which are also known as looped facilities. The global warming potential and running cost of five looped facilities were evaluated by LCA (life cycle assessment) and LCC (life cycle cost) approaches: machine integrated compost, windrow compost, liquid feed, dry feed, and bio-gasification. The LCA results showed low total GHG (greenhouse gas) emissions of -126 and -49 kg-CO(2)/t-waste, respectively, for dry feed and bio-gasification facilities, due to a high substitution effect. The LCC study showed a low running cost for composting facilities of -15,648 and -18,955 yen/t-waste, respectively, due to high revenue from the food waste collection. It was found that the mandatory reporting of food waste emitters to the government increased collection fees; however, the collection fee in animal feed facilities was relatively low because food waste was collected at a low price or nutritious food waste was purchased to produce quality feed. In the characterisation survey of various treatment methods, the composting facilities showed a relatively low environmental impact and a high economic efficiency. Animal feed facilities had a wide distribution of the total GHG emissions, depending on both the energy usage during the drying process and the substitution effect, which were related to the water content of the food waste and the number of recycled products. In comparison with incineration, the majority of the food recycling facilities showed low GHG emissions and economic effectiveness. This paper also reported on the effects of recycling loops by comparing looped and non-looped animal feed facilities, and confirmed that the looped facilities were economically effective, due to an increased amount of food waste collection. Copyright © 2012 Elsevier B.V. All rights reserved.

A digital wireless system for closed-loop inhibition of nociceptive signals

NASA Astrophysics Data System (ADS)

Zuo, Chao; Yang, Xiaofei; Wang, Yang; Hagains, Christopher E.; Li, Ai-Ling; Peng, Yuan B.; Chiao, J.-C.

2012-10-01

Neurostimulation of the spinal cord or brain has been used to inhibit nociceptive signals in pain management applications. Nevertheless, most of the current neurostimulation models are based on open-loop system designs. There is a lack of closed-loop systems for neurostimulation in research with small freely-moving animals and in future clinical applications. Based on our previously developed analog wireless system for closed-loop neurostimulation, a digital wireless system with real-time feedback between recorder and stimulator modules has been developed to achieve multi-channel communication. The wireless system includes a wearable recording module, a wearable stimulation module and a transceiver connected to a computer for real-time and off-line data processing, display and storage. To validate our system, wide dynamic range neurons in the spinal cord dorsal horn have been recorded from anesthetized rats in response to graded mechanical stimuli (brush, pressure and pinch) applied in the hind paw. The identified nociceptive signals were used to automatically trigger electrical stimulation at the periaqueductal gray in real time to inhibit their own activities by the closed-loop design. Our digital wireless closed-loop system has provided a simplified and efficient method for further study of pain processing in freely-moving animals and potential clinical application in patients. Groups 1, 2 and 3 contributed equally to this project.

Antenna Linear-Quadratic-Gaussian (LQG) Controllers: Properties, Limits of Performance, and Tuning Procedure

NASA Technical Reports Server (NTRS)

Gawronski, W.

2004-01-01

Wind gusts are the main disturbances that depreciate tracking precision of microwave antennas and radiotelescopes. The linear-quadratic-Gaussian (LQG) controllers - as compared with the proportional-and-integral (PI) controllers significantly improve the tracking precision in wind disturbances. However, their properties have not been satisfactorily understood; consequently, their tuning is a trial-and-error process. A control engineer has two tools to tune an LQG controller: the choice of coordinate system of the controller model and the selection of weights of the LQG performance index. This article analyzes properties of an open- and closed-loop antenna. It shows that the proper choice of coordinates of the open-loop model simplifies the shaping of the closed-loop performance. The closed-loop properties are influenced by the LQG weights. The article shows the impact of the weights on the antenna closed-loop bandwidth, disturbance rejection properties, and antenna acceleration. The bandwidth and the disturbance rejection characterize the antenna performance, while the acceleration represents the performance limit set by the antenna hardware (motors). The article presents the controller tuning procedure, based on the coordinate selection and the weight properties. The procedure rationally shapes the closed-loop performance, as an alternative to the trial-and-error approach.

Quantitative Feedback Technique (QFT): Bridging the Gap

DTIC Science & Technology

2003-05-01

with Eq. (2) illustrates: (a) the effect of changes of the uncertainty set P(s) upon the output of the closed -loop control system is reduced by the...Bridging the Gap root-locus technique the dominant closed -loop poles are determined for a ζ= 0.45. Table 3 presents the required value of Kx and...degree of decoupling will have been enhanced. Method 1 is then more readily applicable, with the additional benefit of reduced closed -loop BW. E.R.2

An Investigation Relating Longitudinal Pilot-Induced Oscillation Tendency Rating to Describing Function Predictions for Rate-Limited Actuators

DTIC Science & Technology

2004-03-01

2-15 2-10. Pitch Tracking Closed Loop System for Gap Criterion...................................... 2-16 2-11. Four Resulting Gap ...Level 1 Minimize Resonance Closed Loop Bode Diagram ( ) ( ) s sCommand θ θ ( ) ( ) s sCommand θ θ         BWω 2-16 Gap Criterion...System for Gap Criterion In modern fly-by-wire aircraft, feedback is an integral part of obtaining more desirable closed loop flying qualities

Parameter estimation in linear models of the human operator in a closed loop with application of deterministic test signals

NASA Technical Reports Server (NTRS)

Vanlunteren, A.; Stassen, H. G.

1973-01-01

Parameter estimation techniques are discussed with emphasis on unbiased estimates in the presence of noise. A distinction between open and closed loop systems is made. A method is given based on the application of external forcing functions consisting of a sun of sinusoids; this method is thus based on the estimation of Fourier coefficients and is applicable for models with poles and zeros in open and closed loop systems.

A training rule which guarantees finite-region stability for a class of closed-loop neural-network control systems.

PubMed

Kuntanapreeda, S; Fullmer, R R

1996-01-01

A training method for a class of neural network controllers is presented which guarantees closed-loop system stability. The controllers are assumed to be nonlinear, feedforward, sampled-data, full-state regulators implemented as single hidden-layer neural networks. The controlled systems must be locally hermitian and observable. Stability of the closed-loop system is demonstrated by determining a Lyapunov function, which can be used to identify a finite stability region about the regulator point.

Tracking performance and cycle slipping in the all-digital symbol synchronizer loop of the block 5 receiver

NASA Astrophysics Data System (ADS)

Aung, M.

1992-11-01

Computer simulated noise performance of the symbol synchronizer loop (SSL) in the Block 5 receiver is compared with the theoretical noise performance. Good agreement is seen at the higher loop SNR's (SNR(sub L)'s), with gradual degradation as the SNR(sub L) is decreased. For the different cases simulated, cycle slipping is observed (within the simulation time of 10(exp 4) seconds) at SNR(sub L)'s below different thresholds, ranging from 6 to 8.5 dB, comparable to that of a classical phase-locked loop. An important point, however, is that to achieve the desired loop SNR above the seemingly low threshold to avoid cycle slipping, a large data-to-loop-noise power ratio, P(sub D)/(N(sub 0)B(sub L)), is necessary (at least 13 dB larger than the desired SNR(sub L) in the optimum case and larger otherwise). This is due to the large squaring loss (greater than or equal to 13 dB) inherent in the SSL. For the special case of symbol rates approximately equaling the loop update rate, a more accurate equivalent model accounting for an extra loop update period delay (characteristic of the SSL phase detector design) is derived. This model results in a more accurate estimation of the noise-equivalent bandwidth of the loop.

Tracking performance and cycle slipping in the all-digital symbol synchronizer loop of the block 5 receiver

NASA Technical Reports Server (NTRS)

Aung, M.

1992-01-01

Computer simulated noise performance of the symbol synchronizer loop (SSL) in the Block 5 receiver is compared with the theoretical noise performance. Good agreement is seen at the higher loop SNR's (SNR(sub L)'s), with gradual degradation as the SNR(sub L) is decreased. For the different cases simulated, cycle slipping is observed (within the simulation time of 10(exp 4) seconds) at SNR(sub L)'s below different thresholds, ranging from 6 to 8.5 dB, comparable to that of a classical phase-locked loop. An important point, however, is that to achieve the desired loop SNR above the seemingly low threshold to avoid cycle slipping, a large data-to-loop-noise power ratio, P(sub D)/(N(sub 0)B(sub L)), is necessary (at least 13 dB larger than the desired SNR(sub L) in the optimum case and larger otherwise). This is due to the large squaring loss (greater than or equal to 13 dB) inherent in the SSL. For the special case of symbol rates approximately equaling the loop update rate, a more accurate equivalent model accounting for an extra loop update period delay (characteristic of the SSL phase detector design) is derived. This model results in a more accurate estimation of the noise-equivalent bandwidth of the loop.

Molecular genetic analysis of circadian timekeeping in Drosophila

PubMed Central

Hardin, Paul E.

2014-01-01

A genetic screen for mutants that alter circadian rhythms in Drosophila identified the first clock gene - the period (per) gene. The per gene is a central player within a transcriptional feedback loop that represents the core mechanism for keeping circadian time in Drosophila and other animals. The per feedback loop, or core loop, is interlocked with the Clock (Clk) feedback loop, but whether the Clk feedback loop contributes to circadian timekeeping is not known. A series of distinct molecular events are thought to control transcriptional feedback in the core loop. The time it takes to complete these events should take much less than 24h, thus delays must be imposed at different steps within the core loop. As new clock genes are identified, the molecular mechanisms responsible for these delays have been revealed in ever-increasing detail, and provide an in depth accounting of how transcriptional feedback loops keep circadian time. The phase of these feedback loops shift to maintain synchrony with environmental cycles, the most reliable of which is light. Although a great deal is known about cell-autonomous mechanisms of light-induced phase shifting by CRYPTOCHROME (CRY), much less is known about non-cell autonomous mechanisms. CRY mediates phase shifts through an uncharacterized mechanism in certain brain oscillator neurons, and carries out a dual role as a photoreceptor and transcription factor in other tissues. Here I will review how transcriptional feedback loops function to keep time in Drosophila, how they impose delays to maintain a 24h cycle, and how they maintain synchrony with environmental light:dark cycles. The transcriptional feedback loops that keep time in Drosophila are well conserved in other animals, thus what we learn about these loops in Drosophila should continue to provide insight into the operation of analogous transcriptional feedback loops in other animals. PMID:21924977

Development of near real time performance measurements for closed-loop signal systems (CLS) using historical traffic data from existing loop detectors and signal timing data.

DOT National Transportation Integrated Search

2014-10-01

The overarching goal of this research project was to investigate the potential for the NCDOT Central Office Signal Timing : (COST) Section to monitor and assess the quality of field deployed closed-loop signal system plans using the data inherent in ...

A closed loop wireless power transmission system using a commercial RFID transceiver for biomedical applications.

PubMed

Kiani, Mehdi; Ghovanloo, Maysam

2009-01-01

This paper presents a standalone closed loop wireless power transmission system that is built around a commercial off-the-shelf (COTS) radio frequency identification (RFID) transceiver (MLX90121) operating at 13.56 MHz. It can be used for inductively powering implantable biomedical devices in a closed loop fashion. Any changes in the distance and misalignment between transmitter and receiver coils in near-field wireless power transmission can cause a significant change in the received power, which can cause either malfunction or excessive heat dissipation. RFID transceivers are often used open loop. However, their back telemetry capability can be utilized to stabilize the received voltage on the implant. Our measurements showed that the delivered power to the transponder was maintained at 1.48 mW over a range of 6 to 12 cm, while the transmitter power consumption changed from 0.3 W to 1.21 W. The closed loop system can also oppose voltage variations as a result of sudden changes in load current.

An RFID-Based Closed-Loop Wireless Power Transmission System for Biomedical Applications.

PubMed

Kiani, Mehdi; Ghovanloo, Maysam

2010-04-01

This brief presents a standalone closed-loop wireless power transmission system that is built around a commercial off-the-shelf (COTS) radio-frequency identification (RFID) reader (TRF7960) operating at 13.56 MHz. It can be used for inductively powering implantable biomedical devices in a closed loop. Any changes in the distance and misalignment between transmitter and receiver coils in near-field wireless power transmission can cause a significant change in the received power, which can cause either a malfunction or excessive heat dissipation. RFID circuits are often used in an open loop. However, their back telemetry capability can be utilized to stabilize the received voltage on the implant. Our measurements showed that the delivered power to the transponder was maintained at 11.2 mW over a range of 0.5 to 2 cm, while the transmitter power consumption changed from 78 mW to 1.1 W. The closed-loop system can also oppose voltage variations as a result of sudden changes in the load current.

Electrical crosstalk-coupling measurement and analysis for digital closed loop fibre optic gyro

NASA Astrophysics Data System (ADS)

Jin, Jing; Tian, Hai-Ting; Pan, Xiong; Song, Ning-Fang

2010-03-01

The phase modulation and the closed-loop controller can generate electrical crosstalk-coupling in digital closed-loop fibre optic gyro. Four electrical cross-coupling paths are verified by the open-loop testing approach. It is found the variation of ramp amplitude will lead to the alternation of gyro bias. The amplitude and the phase parameters of the electrical crosstalk signal are measured by lock-in amplifier, and the variation of gyro bias is confirmed to be caused by the alternation of phase according to the amplitude of the ramp. A digital closed-loop fibre optic gyro electrical crosstalk-coupling model is built by approximating the electrical cross-coupling paths as a proportion and integration segment. The results of simulation and experiment show that the modulation signal electrical crosstalk-coupling can cause the dead zone of the gyro when a small angular velocity is inputted, and it could also lead to a periodic vibration of the bias error of the gyro when a large angular velocity is inputted.

Closed Loop System Identification with Genetic Algorithms

NASA Technical Reports Server (NTRS)

Whorton, Mark S.

2004-01-01

High performance control design for a flexible space structure is challenging since high fidelity plant models are di.cult to obtain a priori. Uncertainty in the control design models typically require a very robust, low performance control design which must be tuned on-orbit to achieve the required performance. Closed loop system identi.cation is often required to obtain a multivariable open loop plant model based on closed-loop response data. In order to provide an accurate initial plant model to guarantee convergence for standard local optimization methods, this paper presents a global parameter optimization method using genetic algorithms. A minimal representation of the state space dynamics is employed to mitigate the non-uniqueness and over-parameterization of general state space realizations. This control-relevant system identi.cation procedure stresses the joint nature of the system identi.cation and control design problem by seeking to obtain a model that minimizes the di.erence between the predicted and actual closed-loop performance.

Gait adaptation to visual kinematic perturbations using a real-time closed-loop brain computer interface to a virtual reality avatar

PubMed Central

Luu, Trieu Phat; He, Yongtian; Brown, Samuel; Nakagame, Sho; Contreras-Vidal, Jose L.

2017-01-01

Objective The control of human bipedal locomotion is of great interest to the field of lower-body brain computer interfaces (BCIs) for gait rehabilitation. While the feasibility of closed-loop BCI systems for the control of a lower body exoskeleton has been recently shown, multi-day closed-loop neural decoding of human gait in a BCI virtual reality (BCI-VR) environment has yet to be demonstrated. BCI-VR systems provide valuable alternatives for movement rehabilitation when wearable robots are not desirable due to medical conditions, cost, accessibility, usability, or patient preferences. Approach In this study, we propose a real-time closed-loop BCI that decodes lower limb joint angles from scalp electroencephalography (EEG) during treadmill walking to control a walking avatar in a virtual environment. Fluctuations in the amplitude of slow cortical potentials of EEG in the delta band (0.1 – 3 Hz) were used for prediction; thus, the EEG features correspond to time-domain amplitude modulated (AM) potentials in the delta band. Virtual kinematic perturbations resulting in asymmetric walking gait patterns of the avatar were also introduced to investigate gait adaptation using the closed-loop BCI-VR system over a period of eight days. Main results Our results demonstrate the feasibility of using a closed-loop BCI to learn to control a walking avatar under normal and altered visuomotor perturbations, which involved cortical adaptations. The average decoding accuracies (Pearson’s r values) in real-time BCI across all subjects increased from (Hip: 0.18 ± 0.31; Knee: 0.23 ± 0.33; Ankle: 0.14 ± 0.22) on Day 1 to (Hip: 0.40 ± 0.24; Knee: 0.55 ± 0.20; Ankle: 0.29 ± 0.22) on Day 8. Significance These findings have implications for the development of a real-time closed-loop EEG-based BCI-VR system for gait rehabilitation after stroke and for understanding cortical plasticity induced by a closed-loop BCI-VR system. PMID:27064824

Home Use of Day-and-Night Hybrid Closed-Loop Insulin Delivery in Suboptimally Controlled Adolescents With Type 1 Diabetes: A 3-Week, Free-Living, Randomized Crossover Trial.

PubMed

Tauschmann, Martin; Allen, Janet M; Wilinska, Malgorzata E; Thabit, Hood; Acerini, Carlo L; Dunger, David B; Hovorka, Roman

2016-11-01

This study evaluated the feasibility, safety, and efficacy of day-and-night hybrid closed-loop insulin delivery in adolescents with type 1 diabetes under free-living conditions. In an open-label randomized crossover study, 12 suboptimally controlled adolescents on insulin pump therapy (mean ± SD age 14.6 ± 3.1 years; HbA 1c 69 ± 8 mmol/mol [8.5 ± 0.7%]; duration of diabetes 7.8 ± 3.5 years) underwent two 21-day periods in which hybrid closed-loop insulin delivery was compared with sensor-augmented insulin pump therapy in random order. During the closed-loop intervention, a model predictive algorithm automatically directed insulin delivery between meals and overnight. Participants used a bolus calculator to administer prandial boluses. The proportion of time that sensor glucose was in the target range (3.9-10 mmol/L; primary end point) was increased during the closed-loop intervention compared with sensor-augmented insulin pump therapy by 18.8 ± 9.8 percentage points (mean ± SD; P < 0.001), the mean sensor glucose level was reduced by 1.8 ± 1.3 mmol/L (P = 0.001), and the time spent above target was reduced by 19.3 ± 11.3 percentage points (P < 0.001). The time spent with sensor glucose levels below 3.9 mmol/L was low and comparable between interventions (median difference 0.4 [interquartile range -2.2 to 1.3] percentage points; P = 0.33). Improved glucose control during closed-loop was associated with increased variability of basal insulin delivery (P < 0.001) and an increase in the total daily insulin dose (53.5 [39.5-72.1] vs. 51.5 [37.6-64.3] units/day; P = 0.006). Participants expressed positive attitudes and experience with the closed-loop system. Free-living home use of day-and-night closed-loop in suboptimally controlled adolescents with type 1 diabetes is safe, feasible, and improves glucose control without increasing the risk of hypoglycemia. Larger and longer studies are warranted. © 2016 by the American Diabetes Association.

Gait adaptation to visual kinematic perturbations using a real-time closed-loop brain-computer interface to a virtual reality avatar.

PubMed

Luu, Trieu Phat; He, Yongtian; Brown, Samuel; Nakagame, Sho; Contreras-Vidal, Jose L

2016-06-01

The control of human bipedal locomotion is of great interest to the field of lower-body brain-computer interfaces (BCIs) for gait rehabilitation. While the feasibility of closed-loop BCI systems for the control of a lower body exoskeleton has been recently shown, multi-day closed-loop neural decoding of human gait in a BCI virtual reality (BCI-VR) environment has yet to be demonstrated. BCI-VR systems provide valuable alternatives for movement rehabilitation when wearable robots are not desirable due to medical conditions, cost, accessibility, usability, or patient preferences. In this study, we propose a real-time closed-loop BCI that decodes lower limb joint angles from scalp electroencephalography (EEG) during treadmill walking to control a walking avatar in a virtual environment. Fluctuations in the amplitude of slow cortical potentials of EEG in the delta band (0.1-3 Hz) were used for prediction; thus, the EEG features correspond to time-domain amplitude modulated potentials in the delta band. Virtual kinematic perturbations resulting in asymmetric walking gait patterns of the avatar were also introduced to investigate gait adaptation using the closed-loop BCI-VR system over a period of eight days. Our results demonstrate the feasibility of using a closed-loop BCI to learn to control a walking avatar under normal and altered visuomotor perturbations, which involved cortical adaptations. The average decoding accuracies (Pearson's r values) in real-time BCI across all subjects increased from (Hip: 0.18 ± 0.31; Knee: 0.23 ± 0.33; Ankle: 0.14 ± 0.22) on Day 1 to (Hip: 0.40 ± 0.24; Knee: 0.55 ± 0.20; Ankle: 0.29 ± 0.22) on Day 8. These findings have implications for the development of a real-time closed-loop EEG-based BCI-VR system for gait rehabilitation after stroke and for understanding cortical plasticity induced by a closed-loop BCI-VR system.

A LabVIEW model incorporating an open-loop arterial impedance and a closed-loop circulatory system.

PubMed

Cole, R T; Lucas, C L; Cascio, W E; Johnson, T A

2005-11-01

While numerous computer models exist for the circulatory system, many are limited in scope, contain unwanted features or incorporate complex components specific to unique experimental situations. Our purpose was to develop a basic, yet multifaceted, computer model of the left heart and systemic circulation in LabVIEW having universal appeal without sacrificing crucial physiologic features. The program we developed employs Windkessel-type impedance models in several open-loop configurations and a closed-loop model coupling a lumped impedance and ventricular pressure source. The open-loop impedance models demonstrate afterload effects on arbitrary aortic pressure/flow inputs. The closed-loop model catalogs the major circulatory waveforms with changes in afterload, preload, and left heart properties. Our model provides an avenue for expanding the use of the ventricular equations through closed-loop coupling that includes a basic coronary circuit. Tested values used for the afterload components and the effects of afterload parameter changes on various waveforms are consistent with published data. We conclude that this model offers the ability to alter several circulatory factors and digitally catalog the most salient features of the pressure/flow waveforms employing a user-friendly platform. These features make the model a useful instructional tool for students as well as a simple experimental tool for cardiovascular research.

An Environmental for Hardware-in-the-Loop Formation Navigation and Control

NASA Technical Reports Server (NTRS)

Burns, Rich; Naasz, Bo; Gaylor, Dave; Higinbotham, John

2004-01-01

Recent interest in formation flying satellite systems has spurred a considerable amount of research in the relative navigation and control of satellites. Development in this area has included new estimation and control algorithms as well as sensor and actuator development specifically geared toward the relative control problem. This paper describes a simulation facility, the Formation Flying Test Bed (FFTB) at NASA Goddard Space Flight Center, which allows engineers to test new algorithms for the formation flying problem with relevant GN&C hardware in a closed loop simulation. The FFTB currently supports the inclusion of GPS receiver hardware in the simulation loop. Support for satellite crosslink ranging technology is at a prototype stage. This closed-loop, hardware inclusive simulation capability permits testing of navigation and control software in the presence of the actual hardware with which the algorithms must interact. This capability provides the navigation or control developer with a perspective on how the algorithms perform as part of the closed-loop system. In this paper, the overall design and evolution of the FFTB are presented. Each component of the FFTB is then described. Interfaces between the components of the FFTB are shown and the interfaces to and between navigation and control software are described. Finally, an example of closed-loop formation control with GPS receivers in the loop is presented.

40 CFR 1048.110 - How must my engines diagnose malfunctions?

Code of Federal Regulations, 2011 CFR

2011-07-01

... engine-diagnostic requirements apply for engines equipped with three-way catalysts and closed-loop... malfunction whenever the air-fuel ratio does not cross stoichiometry for one minute of intended closed-loop...

Indirect Identification of Linear Stochastic Systems with Known Feedback Dynamics

NASA Technical Reports Server (NTRS)

Huang, Jen-Kuang; Hsiao, Min-Hung; Cox, David E.

1996-01-01

An algorithm is presented for identifying a state-space model of linear stochastic systems operating under known feedback controller. In this algorithm, only the reference input and output of closed-loop data are required. No feedback signal needs to be recorded. The overall closed-loop system dynamics is first identified. Then a recursive formulation is derived to compute the open-loop plant dynamics from the identified closed-loop system dynamics and known feedback controller dynamics. The controller can be a dynamic or constant-gain full-state feedback controller. Numerical simulations and test data of a highly unstable large-gap magnetic suspension system are presented to demonstrate the feasibility of this indirect identification method.

Study on the temperature control mechanism of the tritium breeding blanket for CFETR

NASA Astrophysics Data System (ADS)

Liu, Changle; Qiu, Yang; Zhang, Jie; Zhang, Jianzhong; Li, Lei; Yao, Damao; Li, Guoqiang; Gao, Xiang; Wu, Songtao; Wan, Yuanxi

2017-12-01

The Chinese fusion engineering testing reactor (CFETR) will demonstrate tritium self- sufficiency using a tritium breeding blanket for the tritium fuel cycle. The temperature control mechanism (TCM) involves the tritium production of the breeding blanket and has an impact on tritium self-sufficiency. In this letter, the CFETR tritium target is addressed according to its missions. TCM research on the neutronics and thermal hydraulics issues for the CFETR blanket is presented. The key concerns regarding the blanket design for tritium production under temperature field control are depicted. A systematic theory on the TCM is established based on a multiplier blanket model. In particular, a closed-loop method is developed for the mechanism with universal function solutions, which is employed in the CFETR blanket design activity for tritium production. A tritium accumulation phenomenon is found close to the coolant in the blanket interior, which has a very important impact on current blanket concepts using water coolant inside the blanket. In addition, an optimal tritium breeding ratio (TBR) method based on the TCM is proposed, combined with thermal hydraulics and finite element technology. Meanwhile, the energy gain factor is adopted to estimate neutron heat deposition, which is a key parameter relating to the blanket TBR calculations, considering the structural factors. This work will benefit breeding blanket engineering for the CFETR reactor in the future.

Atmosphere and water quality monitoring on Space Station Freedom

NASA Technical Reports Server (NTRS)

Niu, William

1990-01-01

In Space Station Freedom air and water will be supplied in closed loop systems. The monitoring of air and water qualities will ensure the crew health for the long mission duration. The Atmosphere Composition Monitor consists of the following major instruments: (1) a single focusing mass spectrometer to monitor major air constituents and control the oxygen/nitrogen addition for the Space Station; (2) a gas chromatograph/mass spectrometer to detect trace contaminants; (3) a non-dispersive infrared spectrometer to determine carbon monoxide concentration; and (4) a laser particle counter for measuring particulates in the air. An overview of the design and development concepts for the air and water quality monitors is presented.

Closure of regenerative life support systems: results of the Lunar-Mars Life Support Test Project

NASA Astrophysics Data System (ADS)

Barta, D.; Henninger, D.; Edeen, M.; Lewis, J.; Smith, F.; Verostko, C.

Future long duration human exploration missions away from Earth will require closed-loop regenerative life support systems to reduce launch mass reduce dependency on resupply and increase the level of mission self sufficiency Such systems may be based on the integration of biological and physiocochemical processes to produce potable water breathable atmosphere and nutritious food from metabolic and other mission wastes Over the period 1995 to 1998 a series of ground-based tests were conducted at the National Aeronautics and Space Administration Johnson Space Center to evaluate the performance of advanced closed-loop life support technologies with real human metabolic and hygiene loads Named the Lunar-Mars Life Support Test Project LMLSTP four integrated human tests were conducted with increasing duration complexity and closure The first test LMLSTP Phase I was designed to demonstrate the ability of higher plants to revitalize cabin atmosphere A single crew member spent 15 days within an atmospherically closed chamber containing 11 2 square meters of actively growing wheat Atmospheric carbon dioxide and oxygen levels were maintained by control of the rate of photosynthesis through manipulation of light intensity or the availability of carbon dioxide and included integrated physicochemical systems During the second and third tests LMLSTP Phases II IIa four crew members spent 30 days and 60 days respectively in a larger sealed chamber Advanced physicochemical life support hardware was used to regenerate the atmosphere and produce potable water

Regenerative life support system research and concepts

NASA Technical Reports Server (NTRS)

1988-01-01

Life support systems that involve recycling of atmospheres, water, food and waste are so complex that models incorporating all the interactions and relationships are vital to design, development, simulations, and ultimately to control of space qualified systems. During early modeling studies, FORTRAN and BASIC programs were used to obtain numerical comparisons of the performance of different regenerative concepts. Recently, models were made by combining existing capabilities with expert systems to establish an Intelligent Design Support Environment for simpliflying user interfaces and to address the need for the engineering aspects. Progress was also made toward modeling and evaluating the operational aspects of closed loop life support systems using Time-step and Dynamic simulations over a period of time. Example models are presented which show the status and potential of developed modeling techniques. For instance, closed loop systems involving algae systeMs for atmospheric purification and food supply augmentation, plus models employing high plants and solid waste electrolysis are described and results of initial evaluations are presented.

Microstructure evolution of recrystallized Zircaloy-4 under charged particles irradiation

NASA Astrophysics Data System (ADS)

Gaumé, M.; Onimus, F.; Dupuy, L.; Tissot, O.; Bachelet, C.; Mompiou, F.

2017-11-01

Recrystallized zirconium alloys are used as nuclear fuel cladding tubes of Pressurized Water Reactors. During operation, these alloys are submitted to fast neutron irradiation which leads to their in-reactor deformation and to a change of their mechanical properties. These phenomena are directly related to the microstructure evolution under irradiation and especially to the formation of -type dislocation loops. In the present work, the radiation damage evolution in recrystallized Zircaloy-4 has been studied using charged particles irradiation. The loop nucleation and growth kinetics, and also the helical climb of linear dislocations, were observed in-situ using a High Voltage Electron Microscope (HVEM) under 1 MeV electron irradiation at 673 and 723 K. In addition, 600 keV Zr+ ion irradiations were conducted at the same temperature. Transmission Electron Microscopy (TEM) characterizations have been performed after both types of irradiations, and show dislocation loops with a Burgers vector belonging to planes close to { 10 1 bar 0 } first order prismatic planes. The nature of the loops has been characterized. Only interstitial dislocation loops have been observed after ion irradiation at 723 K. However, after electron irradiation conducted at 673 and 723 K, both interstitial and vacancy loops were observed, the proportion of interstitial loops increasing as the temperature is increased. The loop growth kinetics analysis shows that as the temperature increases, the loop number density decreases and the loop growth rate tends to increase. An increase of the flux leads to an increase of the loop number density and a decrease of the loop growth rate. The results are compared to previous works and discussed in the light of point defects diffusion.

77 FR 55416 - Drawbridge Operation Regulations; Long Island, New York Inland Waterway From East Rockaway Inlet...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-10

...: The Loop Parkway Bridge, mile 0.7, across Long Creek has a vertical clearance in the closed position... deviation the Loop Parkway Bridge and the Meadowbrook Parkway Bridge may remain in the closed position... operation of the Loop Parkway Bridge, mile 0.7, across Long Creek, and the Meadowbrook Parkway Bridge, mile...

Pulsatile desynchronizing delayed feedback for closed-loop deep brain stimulation

PubMed Central

Lysyansky, Borys; Rosenblum, Michael; Pikovsky, Arkady; Tass, Peter A.

2017-01-01

High-frequency (HF) deep brain stimulation (DBS) is the gold standard for the treatment of medically refractory movement disorders like Parkinson’s disease, essential tremor, and dystonia, with a significant potential for application to other neurological diseases. The standard setup of HF DBS utilizes an open-loop stimulation protocol, where a permanent HF electrical pulse train is administered to the brain target areas irrespectively of the ongoing neuronal dynamics. Recent experimental and clinical studies demonstrate that a closed-loop, adaptive DBS might be superior to the open-loop setup. We here combine the notion of the adaptive high-frequency stimulation approach, that aims at delivering stimulation adapted to the extent of appropriately detected biomarkers, with specifically desynchronizing stimulation protocols. To this end, we extend the delayed feedback stimulation methods, which are intrinsically closed-loop techniques and specifically designed to desynchronize abnormal neuronal synchronization, to pulsatile electrical brain stimulation. We show that permanent pulsatile high-frequency stimulation subjected to an amplitude modulation by linear or nonlinear delayed feedback methods can effectively and robustly desynchronize a STN-GPe network of model neurons and suggest this approach for desynchronizing closed-loop DBS. PMID:28273176

Control of nitrification/denitrification in an onsite two-chamber intermittently aerated membrane bioreactor with alkalinity and carbon addition: Model and experiment.

PubMed

Perera, Mahamalage Kusumitha; Englehardt, James D; Tchobanoglous, George; Shamskhorzani, Reza

2017-05-15

Denitrifying membrane bioreactors (MBRs) are being found useful in water reuse treatment systems, including net-zero water (nearly closed-loop), non-reverse osmosis-based, direct potable reuse (DPR) systems. In such systems nitrogen may need to be controlled in the MBR to meet the nitrate drinking water standard in the finished water. To achieve efficient nitrification and denitrification, the addition of alkalinity and external carbon may be required, and control of the carbon feed rate is then important. In this work, an onsite, two-chamber aerobic nitrifying/denitrifying MBR, representing one unit process of a net-zero water, non-reverse osmosis-based DPR system, was modeled as a basis for control of the MBR internal recycling rate, aeration rate, and external carbon feed rate. Specifically, a modification of the activated sludge model ASM2dSMP was modified further to represent the rate of recycling between separate aerobic and anoxic chambers, rates of carbon and alkalinity feed, and variable aeration schedule, and was demonstrated versus field data. The optimal aeration pattern for the modeled reactor configuration and influent matrix was found to be 30 min of aeration in a 2 h cycle (104 m 3 air/d per 1 m 3 /d average influent), to ultimately meet the nitrate drinking water standard. Optimal recycling ratios (inter-chamber flow to average daily flow) were found to be 1.5 and 3 during rest and mixing periods, respectively. The model can be used to optimize aeration pattern and recycling ratio in such MBRs, with slight modifications to reflect reactor configuration, influent matrix, and target nitrogen species concentrations, though some recalibration may be required. Copyright © 2017 Elsevier Ltd. All rights reserved.

Deletion of a unique loop in the mycobacterial F-ATP synthase γ subunit sheds light on its inhibitory role in ATP hydrolysis-driven H(+) pumping.

PubMed

Hotra, Adam; Suter, Manuel; Biuković, Goran; Ragunathan, Priya; Kundu, Subhashri; Dick, Thomas; Grüber, Gerhard

2016-05-01

The F1 FO -ATP synthase is one of the enzymes that is essential to meet the energy requirement of both the proliferating aerobic and hypoxic dormant stages of the life cycle of mycobacteria. Most F-ATP synthases consume ATP in the α3 :β3 headpiece to drive the γ subunit, which couples ATP cleavage with proton pumping in the c ring of FO via the bottom of the γ subunit. ATPase-driven H(+) pumping is latent in mycobacteria. The presence of a unique 14 amino acid residue loop of the mycobacterial γ subunit has been described and aligned in close vicinity to the c-ring loop Priya R et al. (2013) J Bioenerg Biomembr 45, 121-129 Here, we used inverted membrane vesicles (IMVs) of fast-growing Mycobacterium smegmatis and a variety of covalent and non-covalent inhibitors to characterize the ATP hydrolysis activity of the F-ATP synthase inside IMVs. These vesicles formed a platform to investigate the function of the unique mycobaterial γ loop by deleting the respective loop-encoding sequence (γ166-179 ) in the genome of M. smegmatis. ATP hydrolysis-driven H(+) pumping was observed in IMVs containing the Δγ166-179 mutant protein but not for IMVs containing the wild-type F-ATP synthase. In addition, when compared to the wild-type enzyme, IMVs containing the Δγ166-179 mutant protein showed increased ATP cleavage and lower levels of ATP synthesis, demonstrating that the loop affects ATPase activity, ATPase-driven H(+) pumping and ATP synthesis. These results further indicate that the loop may affect coupling of ATP hydrolysis and synthesis in a different mode. © 2016 Federation of European Biochemical Societies.

Assessment and Accommodation of Thermal Expansion of the Internal Active Thermal Control System Coolant During Launch to On-Orbit Activation of International Space Station Elements

NASA Technical Reports Server (NTRS)

Edwards, Darryl; Ungar, Eugene K.; Holt, James M.

2002-01-01

The International Space Station (ISS) employs an Internal Active Thermal Control System (IATCS) comprised of several single-phase water coolant loops. These coolant loops are distributed throughout the ISS pressurized elements. The primary element coolant loops (i.e. U.S. Laboratory module) contain a fluid accumulator to accomodate thermal expansion of the system. Other element coolant loops are parasitic (i.e. Airlock), have no accumulator, and require an alternative approach to insure that the system maximum design pressure (MDP) is not exceeded during the Launch to Activation (LTA) phase. During this time the element loops is a stand alone closed system. The solution approach for accomodating thermal expansion was affected by interactions of system components and their particular limitations. The mathematical solution approach was challenged by the presence of certain unknown or not readily obtainable physical and thermodynamic characteristics of some system components and processes. The purpose of this paper is to provide a brief description of a few of the solutions that evolved over time, a novel mathematical solution to eliminate some of the unknowns or derive the unknowns experimentally, and the testing and methods undertaken.

Assessment and Accommodation of Thermal Expansion of the Internal Active Thermal Control System Coolant During Launch to On-Orbit Activation of International Space Station Elements

NASA Technical Reports Server (NTRS)

Edwards, J. Darryl; Ungar, Eugene K.; Holt, James M.; Turner, Larry D. (Technical Monitor)

2001-01-01

The International Space Station (ISS) employs an Internal Active Thermal Control System (IATCS) comprised of several single-phase water coolant loops. These coolant loops are distributed throughout the ISS pressurized elements. The primary element coolant loops (i.e., US Laboratory module) contain a fluid accumulator to accommodate thermal expansion of the system. Other element coolant loops are parasitic (i.e., Airlock), have no accumulator, and require an alternative approach to insure that the system Maximum Design Pressure (MDP) is not exceeded during the Launch to Activation phase. During this time the element loop is a stand alone closed individual system. The solution approach for accommodating thermal expansion was affected by interactions of system components and their particular limitations. The mathematical solution approach was challenged by the presence of certain unknown or not readily obtainable physical and thermodynamic characteristics of some system components and processes. The purpose of this paper is to provide a brief description of a few of the solutions that evolved over time, a novel mathematical solution to eliminate some of the unknowns or derive the unknowns experimentally, and the testing and methods undertaken.

Whole glove permeation of cyclohexanol through disposable nitrile gloves on a dextrous robot hand and comparison with the modified closed-loop ASTM F739 method 1. No fist clenching.

PubMed

Mathews, Airek R; Que Hee, Shane S

2017-04-01

The aim was to develop a whole glove permeation method for cyclohexanol to generate permeation parameter data for a non-moving dextrous robot hand (normalized breakthrough time t b , standardized breakthrough time t s , steady state permeation rate P s , and diffusion coefficient D). Four types of disposable powderless, unsupported, and unlined nitrile gloves from the same producer were investigated: Safeskin Blue and Kimtech Science Blue, Purple, and Sterling. The whole glove method developed involved a peristaltic pump for water circulation through chemically resistant Viton tubing to continually wash the inner surface of the test glove via holes in the tubing, a dextrous robot hand operated by a microprocessor, a chemically protective nitrile glove to protect the robot hand, an incubator to maintain 35°C temperature, and a hot plate to maintain 35°C at the sampling point of the circulating water. Aliquots of 1.0 mL were sampled at regular time intervals for the first 60 min followed by removal of 0.5 mL aliquots every hour to 8 hr. Quantification was by the internal standard method after gas chromatography-selective ion electron impact mass spectrometry using a non-polar capillary column. The individual glove values of t b and t s differed for the ASTM closed loop method except for Safeskin Blue, but did not for the whole glove method. Most of the kinetic parameters agreed within an order of magnitude for the two techniques. The order of most protective to least protective glove was Blue and Safeskin, then Purple followed by Sterling for the whole gloves. The analogous order for the modified F739 ASTM closed loop method was: Safeskin, Blue, Purple, and Sterling, almost the same as for the whole glove. The Sterling glove was "not recommended" from the modified ASTM data, and was "poor" from the whole glove data.

Tandem dissolution of UO 3 in amide-based acidic ionic liquid and in situ electrodeposition of UO 2 with regeneration of the ionic liquid: a closed cycle

DOE PAGES

Wanigasekara, Eranda; Freiderich, John W.; Sun, Xiao-Guang; ...

2016-05-19

A closed cycle is demonstrated for the tandem dissolution and electroreduction of UO 3 to UO 2 with regeneration of the acidic ionic liquid. The dissolution is achieved by use of the acidic ionic liquid N,N-dimethylacetimidium bis(trifluoromethanesulfonimide) in 1-ethyl-3-methylimidazolium bis(trifluoromethanesulfonimide) serving as the diluent. Bulk electrolysis performed at 1.0 V vs. Ag reference yields a dark brown-black uranium deposit (UO 2) on the cathode. Anodic oxidation of water in the presence of dimethylacetamide regenerates the acidic ionic liquid. We have demonstrated the individual steps in the cycle together with a sequential dissolution, electroreduction, and regeneration cycle.

Tandem dissolution of UO 3 in amide-based acidic ionic liquid and in situ electrodeposition of UO 2 with regeneration of the ionic liquid: a closed cycle

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wanigasekara, Eranda; Freiderich, John W.; Sun, Xiao-Guang

A closed cycle is demonstrated for the tandem dissolution and electroreduction of UO 3 to UO 2 with regeneration of the acidic ionic liquid. The dissolution is achieved by use of the acidic ionic liquid N,N-dimethylacetimidium bis(trifluoromethanesulfonimide) in 1-ethyl-3-methylimidazolium bis(trifluoromethanesulfonimide) serving as the diluent. Bulk electrolysis performed at 1.0 V vs. Ag reference yields a dark brown-black uranium deposit (UO 2) on the cathode. Anodic oxidation of water in the presence of dimethylacetamide regenerates the acidic ionic liquid. We have demonstrated the individual steps in the cycle together with a sequential dissolution, electroreduction, and regeneration cycle.

Comparison of the Shack-Hartmann and plenoptic sensor in closed-loop adaptive optics system

NASA Astrophysics Data System (ADS)

Jiang, Pengzhi; Xu, Jieping; Liang, Yonghui; Mao, Hongjun

2016-03-01

The wavefront sensor is used in adaptive optics (AO) to detect the atmospheric distortion, which feeds back to the deformable mirror to compensate for this distortion. While the Shack-Hartmann sensor has been widely used, the plenoptic sensor was proposed in recent years. The two different wavefront sensing methods have different interpretations and numerical consequences, though they are both slope-based. The plenoptic sensor is compared with the Shack-Hartmann sensor in a closed-loop AO system. Simulations are performed to investigate their performances under closed-loop conditions. The plenoptic sensors both without and with modulation are discussed. The results show that the closed-loop performance of the plenoptic sensor without modulation is worse than that of the Shack-Hartmann sensor when the star for observation is brighter than magnitude 7, but better when the star is fainter. The closed-loop performance of the plenoptic sensor could be improved by modulation, except for the faint star. In summary, the limiting magnitude of the astronomical AO system may be improved by using the plenoptic sensor instead of the Shack-Hartmann sensor, and the modulation of the plenoptic sensor is more suitable for the bright star.

Water and energy link in the cities of the future - achieving net zero carbon and pollution emissions footprint.

PubMed

Novotny, V

2011-01-01

This article discusses the link between water conservation, reclamation, reuse and energy use as related to the goal of achieving the net zero carbon emission footprint in future sustainable cities. It defines sustainable ecocities and outlines quantitatively steps towards the reduction of energy use due to water and used water flows, management and limits in linear and closed loop water/stormwater/wastewater management systems. The three phase water energy nexus diagram may have a minimum inflection point beyond which reduction of water demand may not result in a reduction of energy and carbon emissions. Hence, water conservation is the best alternative solution to water shortages and minimizing the carbon footprint. A marginal water/energy chart is developed and proposed to assist planners in developing future ecocities and retrofitting older communities to achieve sustainability.

Conceptual design and evaluation of selected Space Station concepts, volume 2

NASA Technical Reports Server (NTRS)

1983-01-01

The partially closed cycle environmental control and Life Support Subsystems is examined. Components of the system include air pressure control, heat control, water management, air and water quality monitors, fire detection and suppression, personnel escape, and EVA support subsystems.

Design and Off-Design Performance of 100 kWe-Class Brayton Power Conversion Systems

NASA Technical Reports Server (NTRS)

Johnson, Paul K.; Mason, Lee S.

2005-01-01

The NASA Glenn Research Center in-house computer model Closed Cycle Engine Program (CCEP) was used to explore the design trade space and off-design performance characteristics of 100 kWe-class recuperated Closed Brayton Cycle (CBC) power conversion systems. Input variables for a potential design point included the number of operating units (1, 2, 4), cycle peak pressure (0.5, 1, 2 MPa), and turbo-alternator shaft speed (30, 45, 60 kRPM). The design point analysis assumed a fixed turbine inlet temperature (1150 K), compressor inlet temperature (400 K), helium-xenon working-fluid molecular weight (40 g/mol), compressor pressure ratio (2.0), recuperator effectiveness (0.95), and a Sodium-Potassium (NaK) pumped-loop radiator. The design point options were compared on the basis of thermal input power, radiator area, and mass. For a nominal design point with defined Brayton components and radiator area, off-design cases were examined by reducing turbine inlet temperature (as low as 900 K), reducing shaft speed (as low as 50 percent of nominal), and circulating a percentage (up to 20 percent) of the compressor exit flow back to the gas cooler. The off-design examination sought approaches to reduce thermal input power without freezing the radiator.

Design and Off-Design Performance of 100 kWe-Class Brayton Power Conversion Systems

NASA Astrophysics Data System (ADS)

Johnson, Paul K.; Mason, Lee S.

2005-02-01

The NASA Glenn Research Center in-house computer model Closed Cycle Engine Program (CCEP) was used to explore the design trade space and off-design performance characteristics of 100 kWe-class recuperated Closed Brayton Cycle (CBC) power conversion systems. Input variables for a potential design point included the number of operating units (1, 2, 4), cycle peak pressure (0.5, 1, 2 MPa), and turbo-alternator shaft speed (30,45, 60 kRPM). The design point analysis assumed a fixed turbine inlet temperature (1150 K), compressor inlet temperature (400 K), helium-xenon working-fluid molecular weight (40 g/mol), compressor pressure ratio (2.0), recuperator effectiveness (0.95), and a Sodium-Potassium (NaK) pumped-loop radiator. The design point options were compared on the basis of thermal input power, radiator area, and mass. For a nominal design point with defined Brayton components and radiator area, off-design cases were examined by reducing turbine inlet temperature (as low as 900 K), reducing shaft speed (as low as 50% of nominal), and circulating a percentage (up to 20%) of the compressor exit flow back to the gas cooler. The off-design examination sought approaches to reduce thermal input power without freezing the radiator.

A closed-loop photon beam control study for the Advanced Light Source

DOE Office of Scientific and Technical Information (OSTI.GOV)

Portmann, G.; Bengtsson, J.

1993-05-01

The third generation Advanced Light Source (ALS) will produce extremely bright photon beams using undulators and wigglers. In order to position the photon beams accurate to the micron level, a closed-loop feedback system is being developed. Using photon position monitors and dipole corrector magnets, a closed-loop system can automatically compensate for modeling uncertainties and exogenous disturbances. The following paper will present a dynamics model for the perturbations of the closed orbit of the electron beam in the ALS storage ring including the vacuum chamber magnetic field penetration effects. Using this reference model, two closed-loop feedback algorithms will be compared --more » a classical PI controller and a two degree-of-freedom approach. The two degree-of-freedom method provides superior disturbance rejection while maintaining the desired performance goals. Both methods will address the need to gain schedule the controller due to the time varying dynamics introduced by changing field strengths when scanning the insertion devices.« less

Application of frequency domain handling qualities criteria to the longitudinal landing task

NASA Technical Reports Server (NTRS)

Sarrafian, S. K.; Powers, B. G.

1985-01-01

Three frequency-domain handling qualities criteria have been applied to the observed data to correlate the actual pilot ratings assigned to generic transport configurations with stability augmentation during the longitudinal landing task. The criteria are based on closed-loop techniques using pitch attitude, altitude rate at the pilot station, and altitude at the pilot station as dominating control parameters during this task. It is found that most promising results are obtained with altitude control performed by closing an inner loop on pitch attitude and closing an outer loop on altitude.

Non-polynomial closed string field theory: loops and conformal maps

NASA Astrophysics Data System (ADS)

Hua, Long; Kaku, Michio

1990-11-01

Recently, we proposed the complete classical action for the non-polynomial closed string field theory, which succesfully reproduced all closed string tree amplitudes. (The action was simultaneously proposed by the Kyoto group). In this paper, we analyze the structure of the theory. We (a) compute the explicit conformal map for all g-loop, p-puncture diagrams, (b) compute all one-loop, two-puncture maps in terms of hyper-elliptic functions, and (c) analyze their modular structure. We analyze, but do not resolve, the question of modular invariance.

Closed-loop systems for drug delivery.

PubMed

Fields, Aaron M; Fields, Kevin M; Cannon, Jeremy W

2008-08-01

To discuss closed-loop systems, the engineering behind them, and the application of these systems. The literature demonstrates that closed-loop systems can be used for controlling the depth of anesthesia, muscle relaxation, blood pressure, intravascular volume, and blood glucose levels. The future anesthesiologist may devote less time to easily delegated tasks when in the operating room. The ability of computers to maintain variables in a set range allows some tasks to be automated. Although monitoring of these systems will never be completely eliminated, the necessity for minute-to-minute intervention may.

Study and development of an air conditioning system operating on a magnetic heat pump cycle (design and testing of flow directors)

NASA Astrophysics Data System (ADS)

Wang, Pao-Lien

1992-09-01

This report describes the fabrication, design of flow director, fluid flow direction analysis and testing of flow director of a magnetic heat pump. The objectives of the project are: (1) to fabricate a demonstration magnetic heat pump prototype with flow directors installed; and (2) analysis and testing of flow director and to make sure working fluid loops flow through correct directions with minor mixing. The prototype was fabricated and tested at the Development Testing Laboratory of Kennedy Space Center. The magnetic heat pump uses rear earth metal plates rotate in and out of a magnetic field in a clear plastic housing with water flowing through the rotor plates to provide temperature lift. Obtaining the proper water flow direction has been a problem. Flow directors were installed as flow barriers between separating point of two parallel loops. Function of flow directors were proven to be excellent both analytically and experimentally.

Study and development of an air conditioning system operating on a magnetic heat pump cycle (design and testing of flow directors)

NASA Technical Reports Server (NTRS)

Wang, Pao-Lien

1992-01-01

This report describes the fabrication, design of flow director, fluid flow direction analysis and testing of flow director of a magnetic heat pump. The objectives of the project are: (1) to fabricate a demonstration magnetic heat pump prototype with flow directors installed; and (2) analysis and testing of flow director and to make sure working fluid loops flow through correct directions with minor mixing. The prototype was fabricated and tested at the Development Testing Laboratory of Kennedy Space Center. The magnetic heat pump uses rear earth metal plates rotate in and out of a magnetic field in a clear plastic housing with water flowing through the rotor plates to provide temperature lift. Obtaining the proper water flow direction has been a problem. Flow directors were installed as flow barriers between separating point of two parallel loops. Function of flow directors were proven to be excellent both analytically and experimentally.

Bifurcation phenomena in an impulsive model of non-basal testosterone regulation

NASA Astrophysics Data System (ADS)

Zhusubaliyev, Zhanybai T.; Churilov, Alexander N.; Medvedev, Alexander

2012-03-01

Complex nonlinear dynamics in a recent mathematical model of non-basal testosterone regulation are investigated. In agreement with biological evidence, the pulsatile (non-basal) secretion of testosterone is modeled by frequency and amplitude modulated feedback. It is shown that, in addition to already known periodic motions with one and two pulses in the least period of a closed-loop system solution, cycles of higher periodicity and chaos are present in the model in hand. The broad range of exhibited dynamic behaviors makes the model highly promising in model-based signal processing of hormone data.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bodenheimer, Annette M.; Meilleur, Flora

Trichoderma reesei Cel7A efficiently hydrolyses cellulose. We report here the crystallographic structures of the wild-type TrCel7A catalytic domain (CD) in an open state and, for the first time, in a closed state. Molecular dynamics (MD) simulations indicate that the loops along the CD tunnel move in concerted motions. Together, the crystallographic and MD data suggest that the CD cycles between the tense and relaxed forms that are characteristic of work producing enzymes. Analysis of the interactions formed by R251 provides a structural rationale for the concurrent decrease in product inhibition and catalytic efficiency measured for product-binding site mutants.

Solar heat transport fluid

NASA Technical Reports Server (NTRS)

1978-01-01

The progress made on the development and delivery of noncorrosive fluid subsystems is reported. These subsystems are to be compatible with closed-loop solar heating or combined heating and hot water systems. They are also to be compatible with both metallic and non-metallic plumbing systems. At least 100 gallons of each type of fluid recommended by the contractor will be delivered under the contract. The performance testing of a number of fluids is described.

Experimental and numerical studies on the treatment of wet astronaut trash by forced-convection drying

NASA Astrophysics Data System (ADS)

Arquiza, J. M. R. Apollo; Morrow, Robert; Remiker, Ross; Hunter, Jean B.

2017-09-01

During long-term space missions, astronauts generate wet trash, including food containers with uneaten portions, moist hygiene wipes and wet paper towels. This waste produces two problems: the loss of water and the generation of odors and health hazards by microbial growth. These problems are solved by a closed-loop, forced-convection, heat-pump drying system which stops microbial activity by both pasteurization and desiccation, and recovers water in a gravity-independent porous media condensing heat exchanger. A transient, pseudo-homogeneous continuum model for the drying of wet ersatz trash was formulated for this system. The model is based on the conservation equations for energy and moisture applied to the air and solid phases and includes the unique trash characteristic of having both dry and wet solids. Experimentally determined heat and mass transfer coefficients, together with the moisture sorption equilibrium relationship for the wet material are used in the model. The resulting system of differential equations is solved by the finite-volume method as implemented by the commercial software COMSOL. Model simulations agreed well with experimental data under certain conditions. The validated model will be used in the optimization of the entire closed-loop system consisting of fan, air heater, dryer vessel, heat-pump condenser, and heat-recovery modules.

Day-and-Night Hybrid Closed-Loop Insulin Delivery in Adolescents With Type 1 Diabetes: A Free-Living, Randomized Clinical Trial.

PubMed

Tauschmann, Martin; Allen, Janet M; Wilinska, Malgorzata E; Thabit, Hood; Stewart, Zoë; Cheng, Peiyao; Kollman, Craig; Acerini, Carlo L; Dunger, David B; Hovorka, Roman

2016-07-01

To evaluate feasibility, safety, and efficacy of day-and-night hybrid closed-loop insulin delivery in adolescents with type 1 diabetes under free-living conditions without remote monitoring or supervision. In an open-label, randomized, free-living, crossover study design, 12 adolescents receiving insulin pump therapy (mean [±SD] age 15.4 ± 2.6 years; HbA1c 8.3 ± 0.9%; duration of diabetes 8.2 ± 3.4 years) underwent two 7-day periods of sensor-augmented insulin pump therapy or hybrid closed-loop insulin delivery without supervision or remote monitoring. During the closed-loop insulin delivery, a model predictive algorithm automatically directed insulin delivery between meals and overnight; prandial boluses were administered by participants using a bolus calculator. The proportion of time when the sensor glucose level was in the target range (3.9-10 mmol/L) was increased during closed-loop insulin delivery compared with sensor-augmented pump therapy (72 vs. 53%, P < 0.001; primary end point), the mean glucose concentration was lowered (8.7 vs. 10.1 mmol/L, P = 0.028), and the time spent above the target level was reduced (P = 0.005) without changing the total daily insulin amount (P = 0.55). The time spent in the hypoglycemic range was low and comparable between interventions. Unsupervised day-and-night hybrid closed-loop insulin delivery at home is feasible and safe in young people with type 1 diabetes. Compared with sensor-augmented insulin pump therapy, closed-loop insulin delivery may improve glucose control without increasing the risk of hypoglycemia in adolescents with suboptimally controlled type 1 diabetes. © 2016 by the American Diabetes Association. Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered.

Closing the Referral Loop: an Analysis of Primary Care Referrals to Specialists in a Large Health System.

PubMed

Patel, Malhar P; Schettini, Priscille; O'Leary, Colin P; Bosworth, Hayden B; Anderson, John B; Shah, Kevin P

2018-05-01

Ideally, a referral from a primary care physician (PCP) to a specialist results in a completed specialty appointment with results available to the PCP. This is defined as "closing the referral loop." As health systems grow more complex, regulatory bodies increase vigilance, and reimbursement shifts towards value, closing the referral loop becomes a patient safety, regulatory, and financial imperative. To assess the ability of a large health system to close the referral loop, we used electronic medical record (EMR)-generated data to analyze referrals from a large primary care network to 20 high-volume specialties between July 1, 2015 and June 30, 2016. The primary metric was documented specialist appointment completion rate. Explanatory analyses included documented appointment scheduling rate, individual clinic differences, appointment wait times, and geographic distance to appointments. Of the 103,737 analyzed referral scheduling attempts, only 36,072 (34.8%) resulted in documented complete appointments. Low documented appointment scheduling rates (38.9% of scheduling attempts lacked appointment dates), individual clinic differences in closing the referral loop, and significant differences in wait times and distances to specialists between complete and incomplete appointments drove this gap. Other notable findings include high variation in wait times among specialties and correlation between high wait times and low documented appointment completion rates. The rate of closing the referral loop in this health system is low. Low appointment scheduling rates, individual clinic differences, and patient access issues of wait times and geographic proximity explain much of the gap. This problem is likely common among large health systems with complex provider networks and referral scheduling. Strategies that improve scheduling, decrease variation among clinics, and improve patient access will likely improve rates of closing the referral loop. More research is necessary to determine the impact of these changes and other potential driving factors.

Multi-MW Closed Cycle MHD Nuclear Space Power Via Nonequilibrium He/Xe Working Plasma

NASA Technical Reports Server (NTRS)

Litchford, Ron J.; Harada, Nobuhiro

2011-01-01

Prospects for a low specific mass multi-megawatt nuclear space power plant were examined assuming closed cycle coupling of a high-temperature fission reactor with magnetohydrodynamic (MHD) energy conversion and utilization of a nonequilibrium helium/xenon frozen inert plasma (FIP). Critical evaluation of performance attributes and specific mass characteristics was based on a comprehensive systems analysis assuming a reactor operating temperature of 1800 K for a range of subsystem mass properties. Total plant efficiency was expected to be 55.2% including plasma pre-ionization power, and the effects of compressor stage number, regenerator efficiency and radiation cooler temperature on plant efficiency were assessed. Optimal specific mass characteristics were found to be dependent on overall power plant scale with 3 kg/kWe being potentially achievable at a net electrical power output of 1-MWe. This figure drops to less than 2 kg/kWe when power output exceeds 3 MWe. Key technical issues include identification of effective methods for non-equilibrium pre-ionization and achievement of frozen inert plasma conditions within the MHD generator channel. A three-phase research and development strategy is proposed encompassing Phase-I Proof of Principle Experiments, a Phase-II Subscale Power Generation Experiment, and a Phase-III Closed-Loop Prototypical Laboratory Demonstration Test.

Staged regenerative sorption heat pump

NASA Technical Reports Server (NTRS)

Jones, Jack A. (Inventor)

1995-01-01

A regenerative adsorbent heat pump process and system for cooling and heating a space. A sorbent is confined in a plurality of compressors of which at least four are first stage and at least four are second stage. The first stage operates over a first pressure region and the second stage over a second pressure region which is higher than the first. Sorbate from the first stage enters the second stage. The sorbate loop includes a condenser, expansion valve, evaporator and the compressors. A single sorbate loop can be employed for single-temperature-control such as air conditioning and heating. Two sorbate loops can be used for two-temperature-control as in a refrigerator and freezer. The evaporator temperatures control the freezer and refrigerator temperatures. Alternatively the refrigerator temperature can be cooled by the freezer with one sorbate loop. A heat transfer fluid is circulated in a closed loop which includes a radiator and the compressors. Low temperature heat is exhausted by the radiator. High temperature heat is added to the heat transfer fluid entering the compressors which are desorbing vapor. Heat is transferred from compressors which are sorbing vapor to the heat transfer fluid, and from the heat transfer fluid to the compressors which are desorbing vapor. Each compressor is subjected to the following phases, heating to its highest temperature, cooling down from its highest temperature, cooling to its lowest temperature, and warming up from its lowest temperature. The phases are repeated to complete a cycle and regenerate heat.

Non-active site mutations disturb the loop dynamics, dimerization, viral budding and egress of VP40 of the Ebola virus.

PubMed

Balmith, Marissa; Soliman, Mahmoud E S

2017-02-28

The first account of the dynamic features of the loop region of VP40 of the Ebola virus (EboV) using accelerated molecular dynamics (aMD) simulations is reported herein. Due to its major role in the Ebola life cycle, VP40 is considered a promising therapeutic target. The available experimental data on the N-terminal domain (NTD) loop indicates that mutations K127A, T129A and N130A demonstrate an unrecognized role for NTD-plasma membrane (PM) interaction for efficient VP40-PM localization, oligomerization, matrix assembly and egress. Despite experimental results, the molecular description of VP40 and the information it can provide still remain vague. Therefore, to gain further molecular insight into the effect of mutations on the loop region of VP40 and its effects on the overall protein conformation and VP40 dimerization, aMD simulations and post-dynamic analyses were employed for wildtype (WT) and mutant systems. The results showed significant variations in the presence of mutations as per RMSF, RMSD, R g , PCA and distance calculations in comparison to the WT. These results could provide researchers with insight with regards to the conformational aspects concerning VP40 and its close relation to the experimental data. We believe that the results presented in this study will ultimately provide a useful understanding of the structural landscape of the loop region of VP40, which would contribute towards the discovery of novel EboV inhibitors.

Miniature Fourier transform spectrometer with a dual closed-loop controlled electrothermal micromirror.

PubMed

Han, Fengtian; Wang, Wei; Zhang, Xiaoyang; Xie, Huikai

2016-10-03

A large piston-displacement electrothermal micromirror with closed-loop control of both piston scan and tilting of the mirror plate is demonstrated for use in a miniature Fourier transform spectrometer. Constant scan velocity in an ultra large piston scan range has been demonstrated by the proposed closed-loop piston control scheme which can be easily implemented without considerably increasing system complexity. The experimental results show that the usable linear scan range generated by the micromirror has been extended up to 505 μm. The measured spectral resolution in a compact spectrometer reaches 20 cm^-1, or 0.57 nm at 532 nm wavelength. Compared to other presented systems, this microspectrometer will benefit from the closed-loop thermal actuator approach utilizing both the piston servo and tilt control to provide more consistent spectral response, improved spectral resolution and enhanced robustness to disturbances.

Robust fast controller design via nonlinear fractional differential equations.

PubMed

Zhou, Xi; Wei, Yiheng; Liang, Shu; Wang, Yong

2017-07-01

A new method for linear system controller design is proposed whereby the closed-loop system achieves both robustness and fast response. The robustness performance considered here means the damping ratio of closed-loop system can keep its desired value under system parameter perturbation, while the fast response, represented by rise time of system output, can be improved by tuning the controller parameter. We exploit techniques from both the nonlinear systems control and the fractional order systems control to derive a novel nonlinear fractional order controller. For theoretical analysis of the closed-loop system performance, two comparison theorems are developed for a class of fractional differential equations. Moreover, the rise time of the closed-loop system can be estimated, which facilitates our controller design to satisfy the fast response performance and maintain the robustness. Finally, numerical examples are given to illustrate the effectiveness of our methods. Copyright © 2017 ISA. Published by Elsevier Ltd. All rights reserved.

Similarity Metrics for Closed Loop Dynamic Systems

NASA Technical Reports Server (NTRS)

Whorton, Mark S.; Yang, Lee C.; Bedrossian, Naz; Hall, Robert A.

2008-01-01

To what extent and in what ways can two closed-loop dynamic systems be said to be "similar?" This question arises in a wide range of dynamic systems modeling and control system design applications. For example, bounds on error models are fundamental to the controller optimization with modern control design methods. Metrics such as the structured singular value are direct measures of the degree to which properties such as stability or performance are maintained in the presence of specified uncertainties or variations in the plant model. Similarly, controls-related areas such as system identification, model reduction, and experimental model validation employ measures of similarity between multiple realizations of a dynamic system. Each area has its tools and approaches, with each tool more or less suited for one application or the other. Similarity in the context of closed-loop model validation via flight test is subtly different from error measures in the typical controls oriented application. Whereas similarity in a robust control context relates to plant variation and the attendant affect on stability and performance, in this context similarity metrics are sought that assess the relevance of a dynamic system test for the purpose of validating the stability and performance of a "similar" dynamic system. Similarity in the context of system identification is much more relevant than are robust control analogies in that errors between one dynamic system (the test article) and another (the nominal "design" model) are sought for the purpose of bounding the validity of a model for control design and analysis. Yet system identification typically involves open-loop plant models which are independent of the control system (with the exception of limited developments in closed-loop system identification which is nonetheless focused on obtaining open-loop plant models from closed-loop data). Moreover the objectives of system identification are not the same as a flight test and hence system identification error metrics are not directly relevant. In applications such as launch vehicles where the open loop plant is unstable it is similarity of the closed-loop system dynamics of a flight test that are relevant.

Feasibility of outpatient fully integrated closed-loop control: first studies of wearable artificial pancreas.

PubMed

Kovatchev, Boris P; Renard, Eric; Cobelli, Claudio; Zisser, Howard C; Keith-Hynes, Patrick; Anderson, Stacey M; Brown, Sue A; Chernavvsky, Daniel R; Breton, Marc D; Farret, Anne; Pelletier, Marie-Josée; Place, Jérôme; Bruttomesso, Daniela; Del Favero, Simone; Visentin, Roberto; Filippi, Alessio; Scotton, Rachele; Avogaro, Angelo; Doyle, Francis J

2013-07-01

To evaluate the feasibility of a wearable artificial pancreas system, the Diabetes Assistant (DiAs), which uses a smart phone as a closed-loop control platform. Twenty patients with type 1 diabetes were enrolled at the Universities of Padova, Montpellier, and Virginia and at Sansum Diabetes Research Institute. Each trial continued for 42 h. The United States studies were conducted entirely in outpatient setting (e.g., hotel or guest house); studies in Italy and France were hybrid hospital-hotel admissions. A continuous glucose monitoring/pump system (Dexcom Seven Plus/Omnipod) was placed on the subject and was connected to DiAs. The patient operated the system via the DiAs user interface in open-loop mode (first 14 h of study), switching to closed-loop for the remaining 28 h. Study personnel monitored remotely via 3G or WiFi connection to DiAs and were available on site for assistance. The total duration of proper system communication functioning was 807.5 h (274 h in open-loop and 533.5 h in closed-loop), which represented 97.7% of the total possible time from admission to discharge. This exceeded the predetermined primary end point of 80% system functionality. This study demonstrated that a contemporary smart phone is capable of running outpatient closed-loop control and introduced a prototype system (DiAs) for further investigation. Following this proof of concept, future steps should include equipping insulin pumps and sensors with wireless capabilities, as well as studies focusing on control efficacy and patient-oriented clinical outcomes.

Control of a flexible link by shaping the closed loop frequency response function through optimised feedback filters

NASA Astrophysics Data System (ADS)

Del Vescovo, D.; D'Ambrogio, W.

1995-01-01

A frequency domain method is presented to design a closed-loop control for vibration reduction flexible mechanisms. The procedure is developed on a single-link flexible arm, driven by one rotary degree of freedom servomotor, although the same technique may be applied to similar systems such as supports for aerospace antennae or solar panels. The method uses the structural frequency response functions (FRFs), thus avoiding system identification, that produces modeling uncertainties. Two closed-loops are implemented: the inner loop uses acceleration feedback with the aim of making the FRF similar to that of an equivalent rigid link; the outer loop feeds back displacements to achieve a fast positioning response and null steady state error. In both cases, the controller type is established a priori, while actual characteristics are defined by an optimisation procedure in which the relevant FRF is constrained into prescribed bounds and stability is taken into account.

Evaluation of Bosch-Based Systems Using Non-Traditional Catalysts at Reduced Temperatures

NASA Technical Reports Server (NTRS)

Abney, Morgan B.; Mansell, J. Matthew

2011-01-01

Oxygen and water resupply make open loop atmosphere revitalization (AR) systems unfavorable for long-term missions beyond low Earth orbit. Crucial to closing the AR loop are carbon dioxide reduction systems with low mass and volume, minimal power requirements, and minimal consumables. For this purpose, NASA is exploring using Bosch-based systems. The Bosch process is favorable over state-of-the-art Sabatier-based processes due to complete loop closure. However, traditional operation of the Bosch required high reaction temperatures, high recycle rates, and significant consumables in the form of catalyst resupply due to carbon fouling. A number of configurations have been proposed for next-generation Bosch systems. First, alternative catalysts (catalysts other than steel wool) can be used in a traditional single-stage Bosch reactor to improve reaction kinetics and increase carbon packing density. Second, the Bosch reactor may be split into separate stages wherein the first reactor stage is dedicated to carbon monoxide and water formation via the reverse water-gas shift reaction and the second reactor stage is dedicated to carbon formation. A series system will enable maximum efficiency of both steps of the Bosch reaction, resulting in optimized operation and maximum carbon formation rate. This paper details the results of testing of both single-stage and two-stage Bosch systems with alternative catalysts at reduced temperatures. These results are compared to a traditional Bosch system operated with a steel wool catalyst.

Storage of Renewable Energy by Reduction of CO2 with Hydrogen.

PubMed

Züttel, Andreas; Mauron, Philippe; Kato, Shunsuke; Callini, Elsa; Holzer, Marco; Huang, Jianmei

2015-01-01

The main difference between the past energy economy during the industrialization period which was mainly based on mining of fossil fuels, e.g. coal, oil and methane and the future energy economy based on renewable energy is the requirement for storage of the energy fluxes. Renewable energy, except biomass, appears in time- and location-dependent energy fluxes as heat or electricity upon conversion. Storage and transport of energy requires a high energy density and has to be realized in a closed materials cycle. The hydrogen cycle, i.e. production of hydrogen from water by renewable energy, storage and use of hydrogen in fuel cells, combustion engines or turbines, is a closed cycle. However, the hydrogen density in a storage system is limited to 20 mass% and 150 kg/m(3) which limits the energy density to about half of the energy density in fossil fuels. Introducing CO(2) into the cycle and storing hydrogen by the reduction of CO(2) to hydrocarbons allows renewable energy to be converted into synthetic fuels with the same energy density as fossil fuels. The resulting cycle is a closed cycle (CO(2) neutral) if CO(2) is extracted from the atmosphere. Today's technology allows CO(2) to be reduced either by the Sabatier reaction to methane, by the reversed water gas shift reaction to CO and further reduction of CO by the Fischer-Tropsch synthesis (FTS) to hydrocarbons or over methanol to gasoline. The overall process can only be realized on a very large scale, because the large number of by-products of FTS requires the use of a refinery. Therefore, a well-controlled reaction to a specific product is required for the efficient conversion of renewable energy (electricity) into an easy to store liquid hydrocarbon (fuel). In order to realize a closed hydrocarbon cycle the two major challenges are to extract CO(2) from the atmosphere close to the thermodynamic limit and to reduce CO(2) with hydrogen in a controlled reaction to a specific hydrocarbon. Nanomaterials with nanopores and the unique surface structures of metallic clusters offer new opportunities for the production of synthetic fuels.

Enhanced Performance Controller Design for Stochastic Systems by Adding Extra State Estimation onto the Existing Closed Loop Control

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhou, Yuyang; Zhang, Qichun; Wang, Hong

To enhance the performance of the tracking property , this paper presents a novel control algorithm for a class of linear dynamic stochastic systems with unmeasurable states, where the performance enhancement loop is established based on Kalman filter. Without changing the existing closed loop with the PI controller, the compensative controller is designed to minimize the variances of the tracking errors using the estimated states and the propagation of state variances. Moreover, the stability of the closed-loop systems has been analyzed in the mean-square sense. A simulated example is included to show the effectiveness of the presented control algorithm, wheremore » encouraging results have been obtained.« less

Contribution of seawater recirculation to submarine groundwater discharge and related nutrient fluxes in two tropical bays

NASA Astrophysics Data System (ADS)

Vautier, Camille; Dulaiova, Henrietta

2017-04-01

Hawaiian coastal waters suffer from excess terrestrial nutrient loading, most of which comes from submarine groundwater discharge (SGD). This study quantifies and distinguishes the role of the fresh terrestrial and tidally pumped salt water components of SGD into the nearshore zone of two reefs on the island of Oahu: Maunalua Bay and Kāneohe Bay. The two components of SGD are characterized using isotopic techniques, and the study mainly focuses on the less understood recirculation component. A two-step approach is implemented: first, a conceptual model of groundwater circulation is established; second, nutrient fluxes associated with seawater recirculation are quantified. Groundwater circulation through the beach berm is quantified and characterized using 222Rn and 224Ra activity measurements. Nutrient fluxes are obtained by coupling nutrient concentration measurements and discharge estimates. The isotopic signatures inform us about the influence of the tidal cycle on groundwater circulation. 222Rn, 224Ra, and δ18O isotopes are used to derive apparent ages of the infiltrated seawater and allow us to quantify recirculation rates. The method is also complemented with the use of silicate concentration as tracers of the recirculation process. The trends in apparent ages observed in pore water in Maunalua match previously published conceptual groundwater circulation models and show a sequentially aging pore water circulation loop. However, the ages obtained in Kāneohe suggest a different tidal pumping dynamic that lacks a circulation loop, perhaps resulting from the absence of freshwater discharge. Derived nutrient fluxes show that the autochthonous production of inorganic nitrogen and phosphorus that occurs during seawater recirculation has a significant impact on nutrient cycles in the nearshore areas of the bays. This result suggests that seawater recirculation should be taken into account in biogeochemical studies of coastal areas.

An Environment for Hardware-in-the-Loop Formation Navigation and Control Simulation

NASA Technical Reports Server (NTRS)

Burns, Rich

2004-01-01

Recent interest in formation flying satellite systems has spurred a considerable amount of research in the relative navigation and control of satellites. Development in this area has included new estimation and control algorithms as well as sensor and actuator development specifically geared toward the relative control problem. This paper describes a simulation facility, the Formation Flying Testbed (FFTB) at NASA's Goddard Space Flight Center, which allows engineers to test new algorithms for the formation flying problem with relevant GN&C hardware in a closed loop simulation. The FFTB currently supports the injection of GPS receiver hardware into the simulation loop, and support for satellite crosslink ranging technology is at a prototype stage. This closed-loop, hardware inclusive simulation capability permits testing of navigation and control software in the presence of the actual hardware with which the algorithms must interact. This capability provides the navigation or control developer with a perspective on how the algorithms perform as part of the closed-loop system. In this paper, the overall design and evolution of the FFTB are presented. Each component of the FFTB is then described in detail. Interfaces between the components of the FFTB are shown and the interfaces to and between navigation and control software are described in detail. Finally, an example of closed-loop formation control with GPS receivers in the loop is presented and results are analyzed.

Operation of a cascade air conditioning system with two-phase loop

DOE Office of Scientific and Technical Information (OSTI.GOV)

Feng, Yinshan; Wang, Jinliang; Zhao, Futao

A method of operating a heat transfer system includes starting operation of a first heat transfer fluid vapor/compression circulation loop including a fluid pumping mechanism, a heat exchanger for rejecting thermal energy from a first heat transfer fluid, and a heat absorption side of an internal heat exchanger. A first conduit in a closed fluid circulation loop circulates the first heat transfer fluid therethrough. Operation of a second two-phase heat transfer fluid circulation loop is started after starting operation of the first heat transfer fluid circulation loop. The second heat transfer fluid circulation loop transfers heat to the first heatmore » transfer fluid circulation loop through the internal heat exchanger and includes a heat rejection side of the internal heat exchanger, a liquid pump, and a heat exchanger evaporator. A second conduit in a closed fluid circulation loop circulates a second heat transfer fluid therethrough.« less

Exploration Life Support Critical Questions for Future Human Space Missions

NASA Technical Reports Server (NTRS)

Ewert, Michael K.; Barta, Daniel J.; McQuillan, Jeff

2009-01-01

Exploration Life Support (ELS) is a project under NASA s Exploration Technology Development Program. The ELS Project plans, coordinates and implements the development of advanced life support technologies for human exploration missions in space. Recent work has focused on closed loop atmosphere and water systems for a lunar outpost, including habitats and pressurized rovers. But, what are the critical questions facing life support system developers for these and other future human missions? This paper explores those questions and discusses how progress in the development of ELS technologies can help answer them. The ELS Project includes Atmosphere Revitalization Systems (ARS), Water Recovery Systems (WRS), Waste Management Systems (WMS), Habitation Engineering, Systems Integration, Modeling and Analysis (SIMA), and Validation and Testing, which includes the sub-elements Flight Experiments and Integrated Testing. Systems engineering analysis by ELS seeks to optimize the overall mission architecture by considering all the internal and external interfaces of the life support system and the potential for reduction or reuse of commodities. In particular, various sources and sinks of water and oxygen are considered along with the implications on loop closure and the resulting launch mass requirements.

Shifting the closed-loop spectrum in the optimal linear quadratic regulator problem for hereditary systems

NASA Technical Reports Server (NTRS)

Gibson, J. S.; Rosen, I. G.

1985-01-01

In the optimal linear quadratic regulator problem for finite dimensional systems, the method known as an alpha-shift can be used to produce a closed-loop system whose spectrum lies to the left of some specified vertical line; that is, a closed-loop system with a prescribed degree of stability. This paper treats the extension of the alpha-shift to hereditary systems. As infinite dimensions, the shift can be accomplished by adding alpha times the identity to the open-loop semigroup generator and then solving an optimal regulator problem. However, this approach does not work with a new approximation scheme for hereditary control problems recently developed by Kappel and Salamon. Since this scheme is among the best to date for the numerical solution of the linear regulator problem for hereditary systems, an alternative method for shifting the closed-loop spectrum is needed. An alpha-shift technique that can be used with the Kappel-Salamon approximation scheme is developed. Both the continuous-time and discrete-time problems are considered. A numerical example which demonstrates the feasibility of the method is included.

Shifting the closed-loop spectrum in the optimal linear quadratic regulator problem for hereditary systems

NASA Technical Reports Server (NTRS)

Gibson, J. S.; Rosen, I. G.

1987-01-01

In the optimal linear quadratic regulator problem for finite dimensional systems, the method known as an alpha-shift can be used to produce a closed-loop system whose spectrum lies to the left of some specified vertical line; that is, a closed-loop system with a prescribed degree of stability. This paper treats the extension of the alpha-shift to hereditary systems. As infinite dimensions, the shift can be accomplished by adding alpha times the identity to the open-loop semigroup generator and then solving an optimal regulator problem. However, this approach does not work with a new approximation scheme for hereditary control problems recently developed by Kappel and Salamon. Since this scheme is among the best to date for the numerical solution of the linear regulator problem for hereditary systems, an alternative method for shifting the closed-loop spectrum is needed. An alpha-shift technique that can be used with the Kappel-Salamon approximation scheme is developed. Both the continuous-time and discrete-time problems are considered. A numerical example which demonstrates the feasibility of the method is included.

Design Construction and Operation of a Supercritical Carbon Dioxide (sCO 2) Loop for Investigation of Dry Cooling and Natural Circulation Potential for Use in Advanced Small Modular Reactors Utilizing sCO 2 Power Conversion Cycles.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Middleton, Bobby D.; Rodriguez, Salvador B.; Carlson, Matthew David

This report outlines the work completed for a Laboratory Directed Research and Development project at Sandia National Laboratories from October 2012 through September 2015. An experimental supercritical carbon dioxide (sCO 2 ) loop was designed, built, and o perated. The experimental work demonstrated that sCO 2 can be uti lized as the working fluid in an air - cooled, natural circulation configuration to transfer heat from a source to the ultimate heat sink, which is the surrounding ambient environment in most ca ses. The loop was also operated in an induction - heated, water - cooled configuration that allows formore » measurements of physical parameters that are difficult to isolate in the air - cooled configuration. Analysis included the development of two computational flu id dynamics models. Future work is anticipated to answer questions that were not covered in this project.« less

Solar heating and hot water system installed at Southeast of Saline, Unified School District 306, Mentor, Kansas

NASA Technical Reports Server (NTRS)

1979-01-01

The solar system, installed in a new building, was designed to provide 52 percent of the estimated annual space heating load and 84 percent of the estimated annual potable hot water requirement. The liquid flat plate collectors are ground-mounted and cover a total area of 5125 square feet. The system will provide supplemental heat for the school's closed-loop water-to-air heat pump system and domestic hot water. The storage medium is water inside steel tanks with a capacity of 11,828 gallons for space heating and 1,600 gallons for domestic hot water. The solar heating facility is described and drawings are presented of the completed system which was declared operational in September 1978, and has functioned successfully since.

Physical-chemical treatment of wastes: a way to close turnover of elements in LSS

NASA Astrophysics Data System (ADS)

Kudenko, Yu A.; Gribovskaya, I. V.; Zolotukhin, I. G.

2000-05-01

"Man-plants-physical-chemical unit" system designed for space stations or terrestrial ecohabitats to close steady-state mineral, water and gas exchange is proposed. The physical-chemical unit is to mineralize all inedible plant wastes and physiological human wastes (feces, urine, gray water) by electromagnetically activated hydrogen peroxide in an oxidation reactor. The final product is a mineralized solution containing all elements balanced for plants' requirements. The solution has been successfully used in experiments to grow wheat, beans and radish. The solution was reusable: the evaporated moisture was replenished by the phytotron condensate. Sodium salination of plants was precluded by evaporating reactor-mineralized urine to sodium saturation concentration to crystallize out NaCl which can be used as food for the crew. The remaining mineralized product was brought back for nutrition of plants. The gas composition of the reactor comprises O 2, N 2, CO 2, NH 3, H 2. At the reactor's output hydrogen and oxygen were catalyzed into water, NH 3 was converted in a water trap into NH 4 and used for nutrition of plants. A special accessory at the reactor's output may produce hydrogen peroxide from intrasystem water and gas which makes possible to close gas loops between LSS components.

Physical/chemical closed-loop water-recycling

NASA Technical Reports Server (NTRS)

Herrmann, Cal C.; Wydeven, Theodore

1991-01-01

Water needs, water sources, and means for recycling water are examined in terms appropriate to the water quality requirements of a small crew and spacecraft intended for long duration exploration missions. Inorganic, organic, and biological hazards are estimated for waste water sources. Sensitivities to these hazards for human uses are estimated. The water recycling processes considered are humidity condensation, carbon dioxide reduction, waste oxidation, distillation, reverse osmosis, pervaporation, electrodialysis, ion exchange, carbon sorption, and electrochemical oxidation. Limitations and applications of these processes are evaluated in terms of water quality objectives. Computerized simulation of some of these chemical processes is examined. Recommendations are made for development of new water recycling technology and improvement of existing technology for near term application to life support systems for humans in space. The technological developments are equally applicable to water needs on Earth, in regions where extensive water recycling is needed or where advanced water treatment is essential to meet EPA health standards.

Identification of FOPDT and SOPDT process dynamics using closed loop test.

PubMed

Bajarangbali, Raghunath; Majhi, Somanath; Pandey, Saurabh

2014-07-01

In this paper, identification of stable and unstable first order, second order overdamped and underdamped process dynamics with time delay is presented. Relay with hysteresis is used to induce a limit cycle output and using this information, unknown process model parameters are estimated. State space based generalized analytical expressions are derived to achieve accurate results. To show the performance of the proposed method expressions are also derived for systems with a zero. In real time systems, measurement noise is an important issue during identification of process dynamics. A relay with hysteresis reduces the effect of measurement noise, in addition a new multiloop control strategy is proposed to recover the original limit cycle. Simulation results are included to validate the effectiveness of the proposed method. Copyright © 2014 ISA. Published by Elsevier Ltd. All rights reserved.

Closed-loop assisted versus manual goal-directed fluid therapy during high-risk abdominal surgery: a case-control study with propensity matching.

PubMed

Rinehart, Joseph; Lilot, Marc; Lee, Christine; Joosten, Alexandre; Huynh, Trish; Canales, Cecilia; Imagawa, David; Demirjian, Aram; Cannesson, Maxime

2015-03-19

Goal-directed fluid therapy strategies have been shown to benefit moderate- to high-risk surgery patients. Despite this, these strategies are often not implemented. The aim of this study was to assess a closed-loop fluid administration system in a surgical cohort and compare the results with those for matched patients who received manual management. Our hypothesis was that the patients receiving closed-loop assistance would spend more time in a preload-independent state, defined as percentage of case time with stroke volume variation less than or equal to 12%. Patients eligible for the study were all those over 18 years of age scheduled for hepatobiliary, pancreatic or splenic surgery and expected to receive intravascular arterial blood pressure monitoring as part of their anesthetic care. The closed-loop resuscitation target was selected by the primary anesthesia team, and the system was responsible for implementation of goal-directed fluid therapy during surgery. Following completion of enrollment, each study patient was matched to a non-closed-loop assisted case performed during the same time period using a propensity match to reduce bias. A total of 40 patients were enrolled, 5 were ultimately excluded and 25 matched pairs were selected from among the remaining 35 patients within the predefined caliper distance. There was no significant difference in fluid administration between groups. The closed-loop group spent a significantly higher portion of case time in a preload-independent state (95 ± 6% of case time versus 87 ± 14%, P =0.008). There was no difference in case mean or final stroke volume index (45 ± 10 versus 43 ± 9 and 45 ± 11 versus 42 ± 11, respectively) or mean arterial pressure (79 ± 8 versus 83 ± 9). Case end heart rate was significantly lower in the closed-loop assisted group (77 ± 10 versus 88 ± 13, P =0.003). In this case-control study with propensity matching, clinician use of closed-loop assistance resulted in a greater portion of case time spent in a preload-independent state throughout surgery compared with manual delivery of goal-directed fluid therapy. ClinicalTrials.gov Identifier: NCT02020863. Registered 19 December 2013.

The brain-computer interface cycle.

PubMed

van Gerven, Marcel; Farquhar, Jason; Schaefer, Rebecca; Vlek, Rutger; Geuze, Jeroen; Nijholt, Anton; Ramsey, Nick; Haselager, Pim; Vuurpijl, Louis; Gielen, Stan; Desain, Peter

2009-08-01

Brain-computer interfaces (BCIs) have attracted much attention recently, triggered by new scientific progress in understanding brain function and by impressive applications. The aim of this review is to give an overview of the various steps in the BCI cycle, i.e., the loop from the measurement of brain activity, classification of data, feedback to the subject and the effect of feedback on brain activity. In this article we will review the critical steps of the BCI cycle, the present issues and state-of-the-art results. Moreover, we will develop a vision on how recently obtained results may contribute to new insights in neurocognition and, in particular, in the neural representation of perceived stimuli, intended actions and emotions. Now is the right time to explore what can be gained by embracing real-time, online BCI and by adding it to the set of experimental tools already available to the cognitive neuroscientist. We close by pointing out some unresolved issues and present our view on how BCI could become an important new tool for probing human cognition.

Phase-lock loop frequency control and the dropout problem

NASA Technical Reports Server (NTRS)

Attwood, S.; Kline, A. J.

1968-01-01

Technique automatically sets the frequency of narrow band phase-lock loops within automatic lock-in-range. It presets a phase-lock loop to a desired center frequency with a closed loop electronic frequency discriminator and holds the phase-lock loop to that center frequency until lock is achieved.

POWER GENERATION FROM LIQUID METAL NUCLEAR FUEL

DOEpatents

Dwyer, O.E.

1958-12-23

A nuclear reactor system is described wherein the reactor is the type using a liquid metal fuel, such as a dispersion of fissile material in bismuth. The reactor is designed ln the form of a closed loop having a core sectlon and heat exchanger sections. The liquid fuel is clrculated through the loop undergoing flssion in the core section to produce heat energy and transferrlng this heat energy to secondary fluids in the heat exchanger sections. The fission in the core may be produced by a separate neutron source or by a selfsustained chain reaction of the liquid fuel present in the core section. Additional auxiliary heat exchangers are used in the system to convert water into steam which drives a turbine.

Magnetohydrodynamics (MHD) Engineering Test Facility (ETF) 200 MWe power plant Conceptual Design Engineering Report (CDER)

NASA Technical Reports Server (NTRS)

1981-01-01

The reference conceptual design of the magnetohydrodynamic (MHD) Engineering Test Facility (ETF), a prototype 200 MWe coal-fired electric generating plant designed to demonstrate the commercial feasibility of open cycle MHD, is summarized. Main elements of the design, systems, and plant facilities are illustrated. System design descriptions are included for closed cycle cooling water, industrial gas systems, fuel oil, boiler flue gas, coal management, seed management, slag management, plant industrial waste, fire service water, oxidant supply, MHD power ventilating

Magnetohydrodynamics (MHD) Engineering Test Facility (ETF) 200 MWe power plant Conceptual Design Engineering Report (CDER)

NASA Astrophysics Data System (ADS)

1981-09-01

The reference conceptual design of the magnetohydrodynamic (MHD) Engineering Test Facility (ETF), a prototype 200 MWe coal-fired electric generating plant designed to demonstrate the commercial feasibility of open cycle MHD, is summarized. Main elements of the design, systems, and plant facilities are illustrated. System design descriptions are included for closed cycle cooling water, industrial gas systems, fuel oil, boiler flue gas, coal management, seed management, slag management, plant industrial waste, fire service water, oxidant supply, MHD power ventilating

Classical and adaptive control of ex vivo skeletal muscle contractions using Functional Electrical Stimulation (FES)

PubMed Central

Shoemaker, Adam; Grange, Robert W.; Abaid, Nicole; Leonessa, Alexander

2017-01-01

Functional Electrical Stimulation is a promising approach to treat patients by stimulating the peripheral nerves and their corresponding motor neurons using electrical current. This technique helps maintain muscle mass and promote blood flow in the absence of a functioning nervous system. The goal of this work is to control muscle contractions from FES via three different algorithms and assess the most appropriate controller providing effective stimulation of the muscle. An open-loop system and a closed-loop system with three types of model-free feedback controllers were assessed for tracking control of skeletal muscle contractions: a Proportional-Integral (PI) controller, a Model Reference Adaptive Control algorithm, and an Adaptive Augmented PI system. Furthermore, a mathematical model of a muscle-mass-spring system was implemented in simulation to test the open-loop case and closed-loop controllers. These simulations were carried out and then validated through experiments ex vivo. The experiments included muscle contractions following four distinct trajectories: a step, sine, ramp, and square wave. Overall, the closed-loop controllers followed the stimulation trajectories set for all the simulated and tested muscles. When comparing the experimental outcomes of each controller, we concluded that the Adaptive Augmented PI algorithm provided the best closed-loop performance for speed of convergence and disturbance rejection. PMID:28273101

Efficiently computing exact geodesic loops within finite steps.

PubMed

Xin, Shi-Qing; He, Ying; Fu, Chi-Wing

2012-06-01

Closed geodesics, or geodesic loops, are crucial to the study of differential topology and differential geometry. Although the existence and properties of closed geodesics on smooth surfaces have been widely studied in mathematics community, relatively little progress has been made on how to compute them on polygonal surfaces. Most existing algorithms simply consider the mesh as a graph and so the resultant loops are restricted only on mesh edges, which are far from the actual geodesics. This paper is the first to prove the existence and uniqueness of geodesic loop restricted on a closed face sequence; it contributes also with an efficient algorithm to iteratively evolve an initial closed path on a given mesh into an exact geodesic loop within finite steps. Our proposed algorithm takes only an O(k) space complexity and an O(mk) time complexity (experimentally), where m is the number of vertices in the region bounded by the initial loop and the resultant geodesic loop, and k is the average number of edges in the edge sequences that the evolving loop passes through. In contrast to the existing geodesic curvature flow methods which compute an approximate geodesic loop within a predefined threshold, our method is exact and can apply directly to triangular meshes without needing to solve any differential equation with a numerical solver; it can run at interactive speed, e.g., in the order of milliseconds, for a mesh with around 50K vertices, and hence, significantly outperforms existing algorithms. Actually, our algorithm could run at interactive speed even for larger meshes. Besides the complexity of the input mesh, the geometric shape could also affect the number of evolving steps, i.e., the performance. We motivate our algorithm with an interactive shape segmentation example shown later in the paper.

40 CFR 125.84 - As an owner or operator of a new facility, what must I do to comply with this subpart?

Code of Federal Regulations, 2011 CFR

2011-07-01

... ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS CRITERIA AND STANDARDS FOR THE NATIONAL POLLUTANT DISCHARGE ELIMINATION SYSTEM Requirements Applicable to Cooling Water Intake Structures for New Facilities... that which can be attained by a closed-cycle recirculating cooling water system; (2) You must design...

Analysis & Tools to Spur Increased Deployment of “Waste Heat” Rejection/Recycling Hybrid Ground-source Heat Pump Systems in Hot, Arid or Semiarid Climates Like Texas

DOE Office of Scientific and Technical Information (OSTI.GOV)

Masada, Glenn; Moon, Tess

2013-09-01

This project team analyzed supplemental heat rejection/recovery (SHR) devices or systems that could be used in hybrid ground source heat pump (HGHP) systems located in arid or semi-arid regions in southwestern U.S. Identification of effective SHR solutions would enhance the deployment of ground source heat pumps (GHP) in these regions. In a parallel effort, the team developed integrated GHP models that coupled the building load, heat pump, and ground loop subsystems and which could be applied to residential and commercial office buildings. Then GHP and HGHP performances could be compared in terms of operational performance and life-cycle costs. Several potentialmore » SHR devices were analyzed by applying two strategies: 1) to remove heat directly from the water in the ground loop before it enters the ground and 2) to remove heat in the refrigerant loop of the vapor compression cycle (VCC) of the heat pump so less heat is transferred to the water loop at the condenser of the VCC. Cooling towers, adsorption coolers, and thermoelectric liquid coolers were included in strategy 1, and expanded desuperheaters, thermosyphons, and an optimized VCC were included in strategy 2. Of all SHR devices analyzed, only the cooling tower provided a cost-effective performance enhancement. For the integrated GHP model, the project team selected the building load model HAMBASE and its powerful computational Simulink/MatLab platform, empirical performance map models of the heat pumps based upon manufacturers’ performance data, and a ground loop model developed by Oklahoma State University and rewritten for this project in Simulink/MatLab. The design process used GLHEPRO, also from Oklahoma State University, to size the borehole fields. The building load and ground loop models were compared with simulations from eQuest, ASHRAE 140-2008 standards, EnergyPlus, and GLHEPRO and were found to predict those subsystems’ performance well. The integrated GHP model was applied to a 195m 2 (2100ft 2) residential building and a 4,982m 2 (53,628ft 2) three-story commercial office building, and it ran 10-15 year simulations. The integrated GHP model and its Simulink platform provided residential data, ranging from seconds to years, and commercial office building data, ranging from minutes to years. A cooling tower model was coupled to the base case integrated GHP model for the residential building and the resulting HGHP system provided a cost-effective solution for the Austin, TX location. Simulations for both the residential and commercial building models were run with varying degrees of SHR (device/system not identified) and the results were found to significantly decrease installation costs, increase heat pump efficiency (lower entering water temperature), and prolong the lifetime of the borehole field. Lifetime cycle costs were estimated from the simulation results. Sensitivity studies on system operating performance and lifetime costs were performed on design parameters, such as construction materials, borehole length, borehole configuration and spacing, grout conductivity, and effects of SHR. While some of the results are intuitive, these studies provided quantitative estimates of improved performance and cost. One of the most important results of this sensitivity study is that overall system performance is very sensitive to these design parameters and that modeling and simulation are essential tools to design cost-effective systems.« less

A closed life-support system for space colonies

NASA Technical Reports Server (NTRS)

Johnson, R. D.; Jebens, H. J.; Sweet, H. C.

1977-01-01

In 1975, a system design study was performed to examine a completely self-contained system for a permanent colony of 10,000 inhabitants in space. Fundamental to this design was the life support system. Since resupply from earth is prohibitive in transportation costs, it was decided to use a closed system with the initial supply of oxygen coming from processing of lunar ores, and the supply of carbon, nitrogen and hydrogen from earth. The problem of life support was treated starting with the nutritional and metabolic requirements for the human population, creating a food and water chain sufficient to supply these demands, adding the additional requirements for the animal and plant sources in the food chain, feeding back useful waste products, supplying water as required from different sources, and closing the loop by processing organic wastes into CO2. This concept places the burden of the system upon plants for O2 generation and waste processing the CO2 generation.

Failure Analysis of Network Based Accessible Pedestrian Signals in Closed-Loop Operation

DOT National Transportation Integrated Search

2011-03-01

The potential failure modes of a network based accessible pedestrian system were analyzed to determine the limitations and benefits of closed-loop operation. The vulnerabilities of the system are accessed using the industry standard process known as ...

Analysis and design of a 3rd order velocity-controlled closed-loop for MEMS vibratory gyroscopes.

PubMed

Wu, Huan-ming; Yang, Hai-gang; Yin, Tao; Jiao, Ji-wei

2013-09-18

The time-average method currently available is limited to analyzing the specific performance of the automatic gain control-proportional and integral (AGC-PI) based velocity-controlled closed-loop in a micro-electro-mechanical systems (MEMS) vibratory gyroscope, since it is hard to solve nonlinear functions in the time domain when the control loop reaches to 3rd order. In this paper, we propose a linearization design approach to overcome this limitation by establishing a 3rd order linear model of the control loop and transferring the analysis to the frequency domain. Order reduction is applied on the built linear model's transfer function by constructing a zero-pole doublet, and therefore mathematical expression of each control loop's performance specification is obtained. Then an optimization methodology is summarized, which reveals that a robust, stable and swift control loop can be achieved by carefully selecting the system parameters following a priority order. Closed-loop drive circuits are designed and implemented using 0.35 μm complementary metal oxide semiconductor (CMOS) process, and experiments carried out on a gyroscope prototype verify the optimization methodology that an optimized stability of the control loop can be achieved by constructing the zero-pole doublet, and disturbance rejection capability (D.R.C) of the control loop can be improved by increasing the integral term.

Camera Based Closed Loop Control for Partial Penetration Welding of Overlap Joints

NASA Astrophysics Data System (ADS)

Abt, F.; Heider, A.; Weber, R.; Graf, T.; Blug, A.; Carl, D.; Höfler, H.; Nicolosi, L.; Tetzlaff, R.

Welding of overlap joints with partial penetration in automotive applications is a challenging process, since the laser power must be set very precisely to achieve a proper connection between the two joining partners without damaging the backside of the sheet stack. Even minor changes in welding conditions can lead to bad results. To overcome this problem a camera based closed loop control for partial penetration welding of overlap joints was developed. With this closed loop control it is possible to weld such configurations with a stable process result even under changing welding conditions.

Closed loop models for analyzing the effects of simulator characteristics. [digital simulation of human operators

NASA Technical Reports Server (NTRS)

Baron, S.; Muralidharan, R.; Kleinman, D. L.

1978-01-01

The optimal control model of the human operator is used to develop closed loop models for analyzing the effects of (digital) simulator characteristics on predicted performance and/or workload. Two approaches are considered: the first utilizes a continuous approximation to the discrete simulation in conjunction with the standard optimal control model; the second involves a more exact discrete description of the simulator in a closed loop multirate simulation in which the optimal control model simulates the pilot. Both models predict that simulator characteristics can have significant effects on performance and workload.

A novel Cs-(129)Xe atomic spin gyroscope with closed-loop Faraday modulation.

PubMed

Fang, Jiancheng; Wan, Shuangai; Qin, Jie; Zhang, Chen; Quan, Wei; Yuan, Heng; Dong, Haifeng

2013-08-01

We report a novel Cs-(129)Xe atomic spin gyroscope (ASG) with closed-loop Faraday modulation method. This ASG requires approximately 30 min to start-up and 110 °C to operate. A closed-loop Faraday modulation method for measurement of the optical rotation was used in this ASG. This method uses an additional Faraday modulator to suppress the laser intensity fluctuation and Faraday modulator thermal induced fluctuation. We theoretically and experimentally validate this method in the Cs-(129)Xe ASG and achieved a bias stability of approximately 3.25 °∕h.

Variability of Insulin Requirements Over 12 Weeks of Closed-Loop Insulin Delivery in Adults With Type 1 Diabetes.

PubMed

Ruan, Yue; Thabit, Hood; Leelarathna, Lalantha; Hartnell, Sara; Willinska, Malgorzata E; Dellweg, Sibylle; Benesch, Carsten; Mader, Julia K; Holzer, Manuel; Kojzar, Harald; Evans, Mark L; Pieber, Thomas R; Arnolds, Sabine; Hovorka, Roman

2016-05-01

To quantify variability of insulin requirements during closed-loop insulin delivery. We retrospectively analyzed overnight, daytime, and total daily insulin amounts delivered during a multicenter closed-loop trial involving 32 adults with type 1 diabetes. Participants applied hybrid day-and-night closed-loop insulin delivery under free-living home conditions over 12 weeks. The coefficient of variation was adopted to measure variability of insulin requirements in individual subjects. Data were analyzed from 1,918 nights, 1,883 daytime periods and 1,564 total days characterized by closed-loop use over 85% of time. Variability of overnight insulin requirements (mean [SD] coefficient of variation 31% [4]) was nearly twice as high as variability of total daily requirements (17% [3], P < 0.001) and was also higher than variability of daytime insulin requirements (22% [4], P < 0.001). Overnight insulin requirements were significantly more variable than daytime and total daily amounts. This may explain why some people with type 1 diabetes report frustrating variability in morning glycemia. © 2016 by the American Diabetes Association. Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered.

Closed-Loop Neuromorphic Benchmarks

PubMed Central

Stewart, Terrence C.; DeWolf, Travis; Kleinhans, Ashley; Eliasmith, Chris

2015-01-01

Evaluating the effectiveness and performance of neuromorphic hardware is difficult. It is even more difficult when the task of interest is a closed-loop task; that is, a task where the output from the neuromorphic hardware affects some environment, which then in turn affects the hardware's future input. However, closed-loop situations are one of the primary potential uses of neuromorphic hardware. To address this, we present a methodology for generating closed-loop benchmarks that makes use of a hybrid of real physical embodiment and a type of “minimal” simulation. Minimal simulation has been shown to lead to robust real-world performance, while still maintaining the practical advantages of simulation, such as making it easy for the same benchmark to be used by many researchers. This method is flexible enough to allow researchers to explicitly modify the benchmarks to identify specific task domains where particular hardware excels. To demonstrate the method, we present a set of novel benchmarks that focus on motor control for an arbitrary system with unknown external forces. Using these benchmarks, we show that an error-driven learning rule can consistently improve motor control performance across a randomly generated family of closed-loop simulations, even when there are up to 15 interacting joints to be controlled. PMID:26696820

Material Data Representation of Hysteresis Loops for Hastelloy X Using Artificial Neural Networks

NASA Technical Reports Server (NTRS)

Alam, Javed; Berke, Laszlo; Murthy, Pappu L. N.

1993-01-01

The artificial neural network (ANN) model proposed by Rumelhart, Hinton, and Williams is applied to develop a functional approximation of material data in the form of hysteresis loops from a nickel-base superalloy, Hastelloy X. Several different ANN configurations are used to model hysteresis loops at different cycles for this alloy. The ANN models were successful in reproducing the hysteresis loops used for its training. However, because of sharp bends at the two ends of hysteresis loops, a drift occurs at the corners of the loops where loading changes to unloading and vice versa (the sharp bends occurred when the stress-strain curves were reproduced by adding stress increments to the preceding values of the stresses). Therefore, it is possible only to reproduce half of the loading path. The generalization capability of the network was tested by using additional data for two other hysteresis loops at different cycles. The results were in good agreement. Also, the use of ANN led to a data compression ratio of approximately 22:1.

LCA of waste prevention activities: a case study for drinking water in Italy.

PubMed

Nessi, Simone; Rigamonti, Lucia; Grosso, Mario

2012-10-15

The strategic relevance of waste prevention has considerably increased worldwide during recent years, such that the current European legislation requires the preparation of national waste prevention programmes in which reduction objectives and measures are identified. In such a context, it is possible to recognise how, in order to correctly evaluate the environmental consequences of a prevention activity, a life cycle perspective should be employed. This allows us to go beyond the simple reduction of the generated waste which, alone, does not automatically imply achieving better overall environmental performance, especially when this reduction is not pursued through the simple reduction of consumption. In this study, the energetic and environmental performance of two waste prevention activities considered particularly meaningful for the Italian context were evaluated using life cycle assessment (LCA) methodology. The two activities were the utilisation of public network water (two scenarios) and of refillable bottled water (two scenarios) for drinking purposes, instead of one-way bottled water (three scenarios). The energy demand and specific potential impacts of the four waste prevention scenarios and of the three baseline scenarios were compared with the aim of evaluating whether, and under what conditions, the analysed prevention activities are actually associated with overall energetic and environmental benefits. In typical conditions, the use of public network water directly from the tap results in the best scenario, while if water is withdrawn from public fountains, its further transportation by private car can involve significant impacts. The use of refillable PET bottled water seems the preferable scenario for packaged water consumption, if refillable bottles are transported to local distributors along the same (or a lower) distance as one-way bottles to retailers. The use of refillable glass bottled water is preferable to one-way bottled water only if a distance beneath 150 km separates bottling plants from local distributors and retailers (except for eutrophication indicator which is always slightly worse). To reduce waste generation and to achieve meaningful potential savings of natural resources, energy and greenhouse gas emissions, a reduction in one-way bottled water consumption in Italy is recommended in favour of the use of public network water and of the establishment of short distance-PET bottles based refilling systems. The development of closed loop recycling of one-way PET bottles, and especially the reduction of the distance along which one-way bottled water is transported, are also important. Copyright © 2012 Elsevier Ltd. All rights reserved.

Water Purification

NASA Technical Reports Server (NTRS)

1992-01-01

Silver ionization water purification technology was originally developed for Apollo spacecraft. It was later used to cleanse swimming pools and has now been applied to industrial cooling towers and process coolers. Sensible Technologies, Inc. has added two other technologies to the system, which occupies only six square feet. It is manufactured in three capacities, and larger models are custom built on request. The system eliminates scale, corrosion, algae, bacteria and debris, and because of the NASA technology, viruses and waterborne bacteria are also destroyed. Applications include a General Motors cooling tower, amusement parks, ice manufacture and a closed-loop process cooling system.